Page last updated: 2024-08-23

lofexidine and Hypertension

lofexidine has been researched along with Hypertension in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199011 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alexander, N; Maronde, RF; Velasquez, M; Vlachakis, ND1
Mehta, J; Mehta, P1
Lopez, LM; Mehta, JL2
Beitman, RE; Kuzma, RJ; McMahon, FG; Morledge, J; Mroczek, W; Rolf, CN; Tsai, TH1
Doppelfeld, IS; Graf, E; Prop, G1
Aigner, A; Schmidt, U1
Garrett, BN; Kaplan, NM1
Dustan, HP; Oparil, S; Smith, LR; Wilkins, LH; Winternitz, SR1
Bloomfield, SS; Conradi, EC; Corns-Hurwitz, RH; Cowart, TD; Degenhart, WJ; Fagan, TC; Gaffney, TE; Grossman, WJ; Harmon, GE; Hsu, CY; Lipicky, RJ; Sinkfield, AW1
Bravo, EL; Fouad, FM; Tarazi, RC; Vidt, DG; Williams, H1

Trials

6 trial(s) available for lofexidine and Hypertension

ArticleYear
Hemodynamic effect of lofexidine with a diuretic in hypertension.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:6

    Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Epinephrine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Isometric Contraction; Male; Middle Aged; Norepinephrine

1983
Comparative efficacy and safety of lofexidine and clonidine given alone or concomitantly with hydrochlorothiazide in hypertensive outpatients.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:8a

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged

1982
Lofexidine, a new, antihypertensive imidazoline derivative. Clinical profile of action with single-drug treatment and in combination with hydrochlorothiazide.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:8a

    Topics: Antihypertensive Agents; Blood Chemical Analysis; Blood Pressure; Clonidine; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged

1982
Lofexidine and clonidine in moderate essential hypertension.
    Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:6

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Random Allocation

1981
Antihypertensive effects of lofexidine in patients with essential hypertension.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Catecholamines; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Humans; Hypertension; Middle Aged; Natriuresis; Potassium

1982
Long-term experience with lofexidine in the treatment of mild-to-moderate essential hypertension.
    Drug intelligence & clinical pharmacy, 1985, Volume: 19, Issue:12

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Random Allocation; Time Factors

1985

Other Studies

5 other study(ies) available for lofexidine and Hypertension

ArticleYear
Platelet function in hypertension and effect of therapy.
    The American journal of cardiology, 1981, Volume: 47, Issue:2

    Topics: Adult; Aged; beta-Thromboglobulin; Blood Platelets; Blood Pressure; Clonidine; Heart Rate; Humans; Hypertension; Kidney Function Tests; Male; Middle Aged; Platelet Count; Platelet Function Tests

1981
Comparative efficacy and safety of lofexidine and clonidine in mild to moderately severe systemic hypertension.
    The American journal of cardiology, 1984, Mar-01, Volume: 53, Issue:6

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Random Allocation

1984
Animal experiments on the cardiovascular effects of lofexidine.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:8a

    Topics: Animals; Cats; Clonidine; Dogs; Drug Interactions; Hemodynamics; Hypertension; Hypertension, Renal; Male; Rats; Rats, Inbred Strains; Species Specificity

1982
Lofexidine in the treatment of hypertension: a twice-daily versus one-daily dose comparison with 24-hour blood pressure monitoring.
    Journal of clinical pharmacology, 1981, Volume: 21, Issue:4

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Catecholamines; Clonidine; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Renin

1981
Early hemodynamic and humoral effects of lofexidine.
    Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Antihypertensive Agents; Catecholamines; Clonidine; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged

1981