glyburide has been researched along with Hypertension in 63 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The current study investigated the effects of vildagliptin, a DPP-4 inhibitor, compared to glibenclamide on endothelial function, arterial stiffness, and blood pressure in patients with T2DM and hypertension." | 9.27 | Effect of vildagliptin versus glibenclamide on endothelial function and arterial stiffness in patients with type 2 diabetes and hypertension: a randomized controlled trial. ( Cesarino, CB; Cosenso-Martin, LN; Fernandes, LAB; Giollo-Júnior, LT; Machado, MN; Nakazone, MA; Vilela-Martin, JF; Yugar-Toledo, JC, 2018) |
| "The objective of this study was to examine the effect of the antihyperglycemic agents metformin (insulin sensitizer) and glibenclamide (insulin secretory agent) on the serum level of C-reactive protein (CRP) in well-controlled type 2 diabetics with metabolic syndrome." | 9.10 | Effect of metformin and sulfonylurea on C-reactive protein level in well-controlled type 2 diabetics with metabolic syndrome. ( Akbar, DH, 2003) |
| " Diminished PAME release and its vasorelaxing activity and increased release of angiotensin II in the PVAT suggest a noble role of PVAT in pathogenesis of hypertension." | 7.77 | Role of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertension. ( Chang, HH; Chen, MF; Chen, PY; Chiang, CL; Kuo, JS; Lee, TJ; Lee, YC; Liu, CH; Yeh, JI, 2011) |
| " The improved endothelium-mediated relaxation following ramipril therapy could be attributed to reduced release of cyclo-oxygenase-derived constricting factors and augmented endothelium-dependent hyperpolarization in this type of experimental hypertension." | 7.69 | Ramipril therapy improves arterial dilation in experimental hypertension. ( Hutri-Kähönen, N; Kähönen, M; Pörsti, I; Sallinen, K; Tolvanen, JP; Wu, X, 1997) |
| " The current study investigated the effects of vildagliptin, a DPP-4 inhibitor, compared to glibenclamide on endothelial function, arterial stiffness, and blood pressure in patients with T2DM and hypertension." | 5.27 | Effect of vildagliptin versus glibenclamide on endothelial function and arterial stiffness in patients with type 2 diabetes and hypertension: a randomized controlled trial. ( Cesarino, CB; Cosenso-Martin, LN; Fernandes, LAB; Giollo-Júnior, LT; Machado, MN; Nakazone, MA; Vilela-Martin, JF; Yugar-Toledo, JC, 2018) |
| "The objective of this study was to examine the effect of the antihyperglycemic agents metformin (insulin sensitizer) and glibenclamide (insulin secretory agent) on the serum level of C-reactive protein (CRP) in well-controlled type 2 diabetics with metabolic syndrome." | 5.10 | Effect of metformin and sulfonylurea on C-reactive protein level in well-controlled type 2 diabetics with metabolic syndrome. ( Akbar, DH, 2003) |
| "In type 2 diabetic patients, the vasodilating response to forearm ischemia was the same whether patients were treated with diet treatment alone or with glibenclamide or glimepiride at blood glucose-lowering equipotent closes." | 5.09 | Sulfonylurea treatment of type 2 diabetic patients does not reduce the vasodilator response to ischemia. ( Brunelli, C; Cordera, R; Cordone, S; Olivotti, L; Rossettin, P; Schiavo, M; Spallarossa, P, 2001) |
| " Diminished PAME release and its vasorelaxing activity and increased release of angiotensin II in the PVAT suggest a noble role of PVAT in pathogenesis of hypertension." | 3.77 | Role of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertension. ( Chang, HH; Chen, MF; Chen, PY; Chiang, CL; Kuo, JS; Lee, TJ; Lee, YC; Liu, CH; Yeh, JI, 2011) |
| " Hydrogen sulfide (H(2)S) is a prominent EDRF, since mice lacking its biosynthetic enzyme, cystathionine γ-lyase (CSE), display pronounced hypertension with deficient vasorelaxant responses to acetylcholine." | 3.77 | Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels. ( Amzel, LM; Barodka, VM; Barrow, RK; Berkowitz, DE; Bhunia, AK; Gazi, FK; Gazi, SK; Jung, SM; Mustafa, AK; Sikka, G; Snyder, SH; Steppan, J; Wang, R, 2011) |
| " The improved endothelium-mediated relaxation following ramipril therapy could be attributed to reduced release of cyclo-oxygenase-derived constricting factors and augmented endothelium-dependent hyperpolarization in this type of experimental hypertension." | 3.69 | Ramipril therapy improves arterial dilation in experimental hypertension. ( Hutri-Kähönen, N; Kähönen, M; Pörsti, I; Sallinen, K; Tolvanen, JP; Wu, X, 1997) |
| " During combined treatment with olmesartan plus glibenclamide, no adverse event occurred, and the medications were well tolerated." | 2.72 | Pharmacokinetics and safety of olmesartan medoxomil in combination with glibenclamide in healthy volunteers. ( Bolbrinker, J; Huber, M; Kreutz, R, 2006) |
| "Alloxan 125 mg/kg BW was given intra peritoneal injection on the 8th day to obtain diabetic hypertensive condition." | 1.72 | Blood pressure and blood sugar-lowering effects of purified gambir on diabetic hypertensive Wistar Kyoto rats. ( Abdillah, R; Almahdy, A; Aquista, PG; Armenia, A; Putri, DP; Wahyuni, FS; Zikra, M, 2022) |
| "Cromakalim treatment also prevented alloxan-induced hypercholesterolemia and hypertriglyceridaemia." | 1.31 | Effects of chronic treatment with cromakalim and glibenclamide in alloxan-induced diabetic rats. ( Goyal, RK; Kulkarni, JS; Metha, AA; Santani, DD, 2002) |
| " In conclusion, isolated mesenteric arteries from obese Zucker rats do not show relevant structural changes, and the pharmacodynamic behaviour of such vessels appears to be the same as that of control preparations." | 1.29 | Pharmacodynamic behaviour of isolated resistance vessels obtained from hypertensive-diabetic rats. ( Kam, KL; Pfaffendorf, M; van Zwieten, PA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.59) | 18.7374 |
| 1990's | 30 (47.62) | 18.2507 |
| 2000's | 21 (33.33) | 29.6817 |
| 2010's | 7 (11.11) | 24.3611 |
| 2020's | 4 (6.35) | 2.80 |
| Authors | Studies |
|---|---|
| Armenia, A | 1 |
| Wahyuni, FS | 1 |
| Almahdy, A | 1 |
| Abdillah, R | 1 |
| Aquista, PG | 1 |
| Putri, DP | 1 |
| Zikra, M | 1 |
| Moke, EG | 1 |
| Omogbai, EKI | 1 |
| Osagie-Eweka, SDE | 1 |
| Uchendu, AP | 1 |
| Omogbiya, AI | 1 |
| Ben-Azu, B | 1 |
| Eduviere, AT | 1 |
| Edje, KE | 1 |
| Umukoro, EK | 1 |
| Anachuna, KK | 1 |
| Asiwe, JN | 1 |
| Ahante, E | 1 |
| Oghoghovwe, IJ | 1 |
| Amssayef, A | 1 |
| Ajebli, M | 1 |
| Eddouks, M | 1 |
| Lin, HL | 1 |
| Cheng, PW | 1 |
| Tu, YC | 1 |
| Yeh, BC | 1 |
| Wu, BN | 1 |
| Shen, KP | 1 |
| Cosenso-Martin, LN | 1 |
| Giollo-Júnior, LT | 1 |
| Fernandes, LAB | 1 |
| Cesarino, CB | 1 |
| Nakazone, MA | 1 |
| Machado, MN | 1 |
| Yugar-Toledo, JC | 1 |
| Vilela-Martin, JF | 1 |
| Hung, YC | 1 |
| Lin, CC | 1 |
| Wang, TY | 1 |
| Chang, MP | 1 |
| Sung, FC | 1 |
| Chen, CC | 1 |
| Kamata, Y | 1 |
| Fujita, T | 1 |
| Kato, T | 1 |
| Hayashi, I | 1 |
| Kurosaka, M | 1 |
| Katori, M | 1 |
| Fujita, Y | 1 |
| Majima, M | 1 |
| Bankar, GR | 1 |
| Nampurath, GK | 1 |
| Nayak, PG | 1 |
| Bhattacharya, S | 1 |
| Lee, YC | 1 |
| Chang, HH | 1 |
| Chiang, CL | 1 |
| Liu, CH | 1 |
| Yeh, JI | 1 |
| Chen, MF | 1 |
| Chen, PY | 1 |
| Kuo, JS | 1 |
| Lee, TJ | 1 |
| Mustafa, AK | 1 |
| Sikka, G | 1 |
| Gazi, SK | 1 |
| Steppan, J | 1 |
| Jung, SM | 1 |
| Bhunia, AK | 1 |
| Barodka, VM | 1 |
| Gazi, FK | 1 |
| Barrow, RK | 1 |
| Wang, R | 2 |
| Amzel, LM | 1 |
| Berkowitz, DE | 1 |
| Snyder, SH | 1 |
| Pridjian, G | 1 |
| Semyachkina-Glushkovskaya, OV | 1 |
| Anishchenko, TG | 1 |
| Kuznetsova, AS | 1 |
| Kuznetsova, YV | 1 |
| Bibikova, OA | 1 |
| Sjestnova, AA | 1 |
| Kulkarni, JS | 1 |
| Metha, AA | 1 |
| Santani, DD | 1 |
| Goyal, RK | 1 |
| Kimoto, Y | 1 |
| Kinoshita, H | 2 |
| Nakahata, K | 1 |
| Dojo, M | 1 |
| Iranami, H | 2 |
| Hatano, Y | 2 |
| Akbar, DH | 1 |
| Rosenthal, JH | 1 |
| Balfagón, G | 2 |
| Márquez-Rodas, I | 1 |
| Alvarez, Y | 1 |
| Alonso, MJ | 1 |
| Cachofeiro, V | 1 |
| Salaices, M | 1 |
| Lahera, V | 1 |
| Yosefy, C | 1 |
| Magen, E | 1 |
| Kiselevich, A | 1 |
| Priluk, R | 1 |
| London, D | 1 |
| Volchek, L | 1 |
| Viskoper, RJ | 1 |
| de Moura, RS | 1 |
| Miranda, DZ | 1 |
| Pinto, AC | 1 |
| Sicca, RF | 1 |
| Souza, MA | 1 |
| Rubenich, LM | 1 |
| Carvalho, LC | 1 |
| Rangel, BM | 1 |
| Tano, T | 1 |
| Madeira, SV | 1 |
| Resende, AC | 1 |
| Ghosh, M | 1 |
| Hanna, ST | 1 |
| McNeill, JR | 1 |
| Ménard, J | 1 |
| Payette, H | 1 |
| Baillargeon, JP | 1 |
| Maheux, P | 1 |
| Lepage, S | 1 |
| Tessier, D | 1 |
| Ardilouze, JL | 1 |
| Sankar, D | 1 |
| Rao, MR | 1 |
| Sambandam, G | 1 |
| Pugalendi, KV | 1 |
| Huber, M | 1 |
| Bolbrinker, J | 1 |
| Kreutz, R | 1 |
| Khurana, A | 1 |
| Vinayek, N | 1 |
| Shi, YX | 1 |
| Chen, Y | 1 |
| Zhu, YZ | 1 |
| Huang, GY | 1 |
| Moore, PK | 1 |
| Huang, SH | 1 |
| Yao, T | 1 |
| Zhu, YC | 1 |
| Chen, X | 1 |
| Patel, K | 1 |
| Connors, SG | 1 |
| Mendonca, M | 1 |
| Welch, WJ | 1 |
| Wilcox, CS | 1 |
| Juan, O | 1 |
| Esteban, E | 1 |
| Sotillo, J | 1 |
| Alberola, V | 1 |
| Mozaffari, MS | 1 |
| Schaffer, SW | 1 |
| Blanco-Rivero, J | 1 |
| Gamallo, C | 1 |
| Aras-López, R | 1 |
| Cobeño, L | 1 |
| Cogolludo, A | 1 |
| Pérez-Vizcaino, F | 1 |
| Ferrer, M | 1 |
| Bretzke, G | 1 |
| Taguchi, H | 1 |
| Faraci, FM | 1 |
| Kitazono, T | 2 |
| Heistad, DD | 1 |
| Kam, KL | 2 |
| Pfaffendorf, M | 2 |
| van Zwieten, PA | 2 |
| Ahmad, S | 1 |
| Kau, ST | 1 |
| Zografos, P | 1 |
| Do, ML | 1 |
| Halterman, TJ | 1 |
| McConville, MW | 1 |
| Yochim, CL | 1 |
| Trivedi, S | 1 |
| Howe, BB | 1 |
| Li, JH | 1 |
| Gao, Y | 1 |
| Nishimura, Y | 1 |
| Suzuki, A | 1 |
| Yoshida, K | 1 |
| Clapham, JC | 1 |
| Trail, BK | 1 |
| Hamilton, TC | 1 |
| Press, JB | 1 |
| McNally, JJ | 1 |
| Sanfilippo, PJ | 1 |
| Addo, MF | 1 |
| Loughney, D | 1 |
| Giardino, E | 1 |
| Katz, LB | 1 |
| Falotico, R | 1 |
| Haertlein, BJ | 1 |
| Ayani Almagia, I | 1 |
| Muñoz Muñoz, MJ | 1 |
| Hernández Macías, C | 1 |
| Gutiérrez Herrador, G | 1 |
| Rodríguez Sasiain, JM | 1 |
| Takemoto, T | 1 |
| Eda, M | 1 |
| Okada, T | 1 |
| Sakashita, H | 1 |
| Matzno, S | 1 |
| Gohda, M | 1 |
| Ebisu, H | 1 |
| Nakamura, N | 1 |
| Fukaya, C | 1 |
| Hihara, M | 1 |
| Riddle, MC | 1 |
| Kolias, TJ | 1 |
| Chai, S | 1 |
| Webb, RC | 1 |
| Hayakawa, H | 1 |
| Hirata, Y | 1 |
| Suzuki, E | 1 |
| Sugimoto, T | 2 |
| Matsuoka, H | 1 |
| Kikuchi, K | 1 |
| Nagano, T | 1 |
| Hirobe, M | 1 |
| Mäkynen, H | 1 |
| Kähönen, M | 2 |
| Wu, X | 2 |
| Arvola, P | 1 |
| Pörsti, I | 2 |
| Takaba, H | 1 |
| Nagao, T | 1 |
| Ibayashi, S | 1 |
| Fujii, K | 1 |
| Fujishima, M | 1 |
| Numaguchi, K | 1 |
| Egashira, K | 1 |
| Sakata, M | 1 |
| Shimokawa, H | 1 |
| Takeshita, A | 1 |
| Nishimura, M | 1 |
| Takahashi, H | 1 |
| Nanbu, A | 1 |
| Sakamoto, M | 1 |
| Nakanishi, T | 1 |
| Yoshimura, M | 1 |
| Nakagawa, C | 1 |
| Asayama, J | 1 |
| Tatsumi, T | 1 |
| Matoba, S | 1 |
| Kobara, M | 1 |
| Tanaka, T | 1 |
| Ohta, B | 1 |
| Kawahara, A | 1 |
| Tsuruyama, K | 1 |
| Katamura, M | 1 |
| Nakagawa, M | 1 |
| Hutri-Kähönen, N | 1 |
| Tolvanen, JP | 1 |
| Sallinen, K | 1 |
| Izumi, H | 1 |
| Kawahara, J | 1 |
| Takeuchi, A | 1 |
| Izawa, T | 1 |
| Ogawa, N | 1 |
| Li, MK | 1 |
| Tsui, CP | 1 |
| Sung, JJ | 1 |
| Scremin, OU | 1 |
| Leung, FW | 1 |
| Piccolo, I | 1 |
| Sterzi, R | 1 |
| Thiella, G | 1 |
| Kwan, YW | 1 |
| To, KW | 1 |
| Lau, WM | 1 |
| Tsang, SH | 1 |
| Sunano, S | 1 |
| Watanabe, H | 1 |
| Tanaka, S | 1 |
| Sekiguchi, F | 1 |
| Shimamura, K | 1 |
| Miossec, P | 1 |
| Lormeau, B | 1 |
| Valensi, P | 1 |
| Arthuis, F | 1 |
| Amouroux, J | 1 |
| Attali, JR | 1 |
| Lee, YM | 1 |
| Peng, YY | 1 |
| Sheu, JR | 1 |
| Cheng, CY | 1 |
| Yen, MH | 1 |
| Honda, H | 1 |
| Unemoto, T | 1 |
| Kogo, H | 1 |
| Kakutani, T | 1 |
| Fattinger, K | 1 |
| Funk, C | 1 |
| Pantze, M | 1 |
| Weber, C | 1 |
| Reichen, J | 1 |
| Stieger, B | 1 |
| Meier, PJ | 1 |
| Spallarossa, P | 1 |
| Schiavo, M | 1 |
| Rossettin, P | 1 |
| Cordone, S | 1 |
| Olivotti, L | 1 |
| Cordera, R | 1 |
| Brunelli, C | 1 |
| Birkeland, KI | 1 |
| Chatzipanagiotou, F | 1 |
| Hanssen, KF | 1 |
| Vaaler, S | 1 |
| Miyata, N | 1 |
| Tsuchida, K | 1 |
| Otomo, S | 1 |
| Arauz-Pacheco, C | 1 |
| Ramirez, LC | 1 |
| Rios, JM | 1 |
| Raskin, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 12-week Randomized Study to Compare the Effect of Vildagliptin vs. Glibenclamide Associated to Metformin in Endothelial Function in Patients With Type 2 Diabetes and Hypertension[NCT02145611] | Phase 4 | 50 participants (Actual) | Interventional | 2013-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for glyburide and Hypertension
| Article | Year |
|---|---|
What is new in diabetes?: best articles from the past year.
Topics: Body Weight; Cholesterol, HDL; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Glyburide; | 2012 |
7 trials available for glyburide and Hypertension
| Article | Year |
|---|---|
Effect of vildagliptin versus glibenclamide on endothelial function and arterial stiffness in patients with type 2 diabetes and hypertension: a randomized controlled trial.
Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diabetes Mellitus, Type 2; Endot | 2018 |
Effect of metformin and sulfonylurea on C-reactive protein level in well-controlled type 2 diabetics with metabolic syndrome.
Topics: Blood Glucose; Body Mass Index; C-Reactive Protein; Diabetes Mellitus, Type 2; Female; Glyburide; Hu | 2003 |
Rosiglitazone improves, while Glibenclamide worsens blood pressure control in treated hypertensive diabetic and dyslipidemic subjects via modulation of insulin resistance and sympathetic activity.
Topics: Administration, Oral; Albuminuria; Blood Glucose; Blood Pressure; Body Mass Index; Brachial Artery; | 2004 |
Efficacy of intensive multitherapy for patients with type 2 diabetes mellitus: a randomized controlled trial.
Topics: Adult; Aged; Blood Glucose; Blood Pressure; Cholesterol, LDL; Diabetes Mellitus, Type 2; Dyslipidemi | 2005 |
Pharmacokinetics and safety of olmesartan medoxomil in combination with glibenclamide in healthy volunteers.
Topics: Adolescent; Adult; Antihypertensive Agents; Area Under Curve; Cross-Over Studies; Diabetes Mellitus, | 2006 |
Different takes on the relationship of insulin treatment to blood pressure.
Topics: Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Gl | 1993 |
Sulfonylurea treatment of type 2 diabetic patients does not reduce the vasodilator response to ischemia.
Topics: Aged; Aged, 80 and over; Blood Pressure; Brachial Artery; Diabetes Mellitus, Type 2; Diet, Diabetic; | 2001 |
55 other studies available for glyburide and Hypertension
| Article | Year |
|---|---|
Blood pressure and blood sugar-lowering effects of purified gambir on diabetic hypertensive Wistar Kyoto rats.
Topics: Alloxan; Animals; Antioxidants; Blood Glucose; Blood Pressure; Captopril; Catechin; Diabetes Mellitu | 2022 |
Co-administration of metformin and/or glibenclamide with losartan reverse N
Topics: Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Esters; Glyburide | 2023 |
Aqueous extract of oakmoss produces antihypertensive activity in L-NAME-induced hypertensive rats through sGC-cGMP pathway.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Arterial Pressure; B | 2021 |
The effectiveness comparisons of eugenosedin-A, glibenclamide and pioglitazone on diabetes mellitus induced by STZ/NA and high-fat diet in SHR.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diet, High-Fat; Glyburide; Hypertension; Hy | 2021 |
Oral hypoglycaemic agents and the development of non-fatal cardiovascular events in patients with type 2 diabetes mellitus.
Topics: Administration, Oral; Adult; Aged; Cardiovascular Diseases; Cohort Studies; Comorbidity; Coronary Di | 2013 |
An ATP-sensitive potassium channel blocker suppresses sodium-induced hypertension through increased secretion of urinary kallikrein.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Creatinine; Erythrocytes; Glyburid | 2009 |
A possible correlation between the correction of endothelial dysfunction and normalization of high blood pressure levels by 1,3,4-oxadiazole derivative, an L-type Ca2+ channel blocker in deoxycorticosterone acetate and N(G)-nitro-l-arginine hypertensive r
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Calcium Channel Blockers; Calcium Channels, L-Typ | 2010 |
Role of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertension.
Topics: 4-Aminopyridine; Adipocytes; Adipose Tissue; Angiotensin II; Animals; Aorta; Calcium; Cells, Culture | 2011 |
Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels.
Topics: Acetylcholine; Animals; Aorta; Cells, Cultured; Charybdotoxin; Cystathionine gamma-Lyase; Endotheliu | 2011 |
Mechanisms for vascular effects of androgens in normotensive and hypertensive rats.
Topics: Acetylcholine; Androgens; Animals; Blood Pressure; Endothelium, Vascular; Epoprostenol; Glyburide; H | 2012 |
Effects of chronic treatment with cromakalim and glibenclamide in alloxan-induced diabetic rats.
Topics: Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Cromakalim; Diabetes Mellitus, Expe | 2002 |
Mexiletine differentially modulates vasorelaxation mediated by adenosine triphosphate-sensitive K+ channels in aortas from normotensive and hypertensive rats.
Topics: Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; ATP-Binding Cassette Transporters; Cromakalim; Dos | 2003 |
Acarbose for patients with hypertension and impaired glucose tolerance.
Topics: Acarbose; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Glucose Intolerance; Glyburide; Humans | 2003 |
Aldosterone modulates neural vasomotor response in hypertension: role of calcitonin gene-related peptide.
Topics: Adenine; Adenosine Triphosphate; Aldosterone; Animals; Anti-Arrhythmia Agents; Calcitonin Gene-Relat | 2004 |
Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine.
Topics: Acetylcholine; Administration, Oral; Alcohol Drinking; Animals; Apamin; Atropine; Blood Pressure; Br | 2004 |
Altered vascular reactivity and KATP channel currents in vascular smooth muscle cells from deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Blood Pressure; Canada; Cromakalim; Desoxycorticos | 2004 |
A pilot study of open label sesame oil in hypertensive diabetics.
Topics: Aged; Antihypertensive Agents; Antioxidants; Atenolol; Blood Glucose; Body Mass Index; Diabetes Comp | 2006 |
Case 36-2006: a pregnant woman with new hypertension.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Diabetes, Gestational; Female; Glyburide; Humans | 2007 |
Chronic sodium hydrosulfide treatment decreases medial thickening of intramyocardial coronary arterioles, interstitial fibrosis, and ROS production in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Chemical Analysis; Blood Pressure; Cardiomegaly; Cardiotonic | 2007 |
Acute antihypertensive action of Tempol in the spontaneously hypertensive rat.
Topics: Amitrole; Animals; Antihypertensive Agents; Blood Pressure; Buthionine Sulfoximine; Catalase; Cromak | 2007 |
Atrial flutter and myocardial infarction-like ECG changes as manifestations of left ventricle involvement from lung carcinoma.
Topics: Antihypertensive Agents; Antineoplastic Combined Chemotherapy Protocols; Atrial Flutter; Carboplatin | 2008 |
Effect of pressure overload on cardioprotection of mitochondrial KATP channels and GSK-3beta: interaction with the MPT pore.
Topics: Animals; Cardiotonic Agents; Cyclosporine; Diazoxide; Disease Models, Animal; Glyburide; Glycogen Sy | 2008 |
Decreased expression of aortic KIR6.1 and SUR2B in hypertension does not correlate with changes in the functional role of K(ATP) channels.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; ATP-Binding Cassette Transporters; Blotting, West | 2008 |
[Effect of beta receptor blockers on carbohydrate metabolism].
Topics: Adrenergic beta-Antagonists; Aged; Blood Glucose; Carbohydrate Metabolism; Coronary Disease; Diabete | 1981 |
Relaxation of the aorta during hypoxia is impaired in chronically hypertensive rats.
Topics: Animals; Aorta; Charybdotoxin; Chronic Disease; Glyburide; Hypertension; Hypoxia; Male; Nitroprussid | 1995 |
Drug-induced endothelium-dependent and -independent relaxations in isolated resistance vessels taken from simultaneously hypertensive and streptozotocin-diabetic rats.
Topics: Animals; Benzopyrans; Bradykinin; Calcium; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, | 1994 |
Drug interaction induces hypoglycemia.
Topics: Diabetes Mellitus, Type 2; Drug Interactions; Enalapril; Female; Glyburide; Humans; Hypertension; Hy | 1995 |
Characterization of ATP-sensitive potassium channel-blocking activity of ZENECA ZM181,037, a eukalemic diuretic.
Topics: Acetamides; Adenosine Triphosphate; Administration, Oral; Animals; Benzopyrans; Blood Glucose; Blood | 1994 |
Relaxant effects of calcitonin gene-related peptide on isolated small renal arteries in stroke-prone spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Colforsin; Dose-Response Relationship, Drug | 1994 |
K+ channel activators, acute glucose tolerance and glibenclamide-induced hypoglycaemia in the hypertensive rat.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Benzopyrans; Blood Glucose; Blood Pressure; | 1994 |
Novel thieno[2,3-b]- and [3,4-b]pyrans as potassium channel openers. Thiophene systems--XVII.
Topics: Animals; Antihypertensive Agents; Aorta; Benzopyrans; Cromakalim; Drug Evaluation, Preclinical; Glyb | 1993 |
[Hypoglycemia associated with angiotensin-converting enzyme inhibitors].
Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Diabetes Complications; Di | 1993 |
Novel potassium channel openers: synthesis and pharmacological evaluation of new N-(substituted-3-pyridyl)-N'-alkylthioureas and related compounds.
Topics: 4-Aminopyridine; Amifampridine; Animals; Antihypertensive Agents; Biomechanical Phenomena; Glyburide | 1994 |
Potassium channel antagonists and vascular reactivity in stroke-prone spontaneously hypertensive rats.
Topics: 4-Aminopyridine; Amifampridine; Animals; Apamin; Barium; Cardiovascular System; Carotid Arteries; Ce | 1993 |
Mechanisms for altered endothelium-dependent vasorelaxation in isolated kidneys from experimental hypertensive rats.
Topics: Acetylcholine; Animals; Arginine; Desoxycorticosterone; Endothelium, Vascular; Glyburide; Hypertensi | 1993 |
Endothelial function in deoxycorticosterone-NaCl hypertension: effect of calcium supplementation.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Apamin; Arginine; Blood Pressure; Calcium, Dietary; D | 1996 |
Altered cerebrovascular response to a potassium channel opener in hypertensive rats.
Topics: Adenosine Triphosphate; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; | 1996 |
Coronary vascular ATP-sensitive potassium channels are activated to a greater extent in spontaneously hypertensive rats than in Wistar-Kyoto rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; | 1996 |
Cerebral adenosine triphosphate-sensitive K+ channels may be impaired during acute cerebral ischemia in spontaneously hypertensive rats.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Antidiuretic Hormone Receptor Antagon | 1996 |
Effects of glibenclamide and nicorandil in post-ischaemic contractile dysfunction of perfused hearts in normotensive and spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cardiac Volume; Creatine Kinase; Glyburide; Heart Rate; Hemodynamics; Hyper | 1996 |
Pharmacodynamic behaviour of isolated resistance vessels obtained from hypertensive-diabetic rats.
Topics: Animals; Benzopyrans; Blood Glucose; Calcium Channels; Calcium Chloride; Cromakalim; Glyburide; Hype | 1996 |
Ramipril therapy improves arterial dilation in experimental hypertension.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Cyclooxygenase Inhibitors; Diclofe | 1997 |
In vitro and in vivo vasodilating effects of KRN4884, Ki1769 and Ki3005, pyridinecarboxamidine derivatives.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Dose-Resp | 1997 |
Potassium channels participate in gastric mucosal protection in rats with partial portal vein ligation.
Topics: Animals; Blood Pressure; Gastric Mucosa; Glyburide; Hypertension; Hypoglycemic Agents; Male; Portal | 1998 |
Chorea in hyperglycemia.
Topics: Aged; Aged, 80 and over; Brain; Chorea; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Gl | 1998 |
Comparison of the vascular relaxant effects of ATP-dependent K+ channel openers on aorta and pulmonary artery isolated from spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Adenosine Triphosphate; Aminoquinolines; Animals; Aorta, Thoracic; Apamin; Benzopyrans; Charybdotoxi | 1999 |
Endothelium-derived relaxing, contracting and hyperpolarizing factors of mesenteric arteries of hypertensive and normotensive rats.
Topics: Acetylcholine; Animals; Apamin; Blood Pressure; Body Weight; Bridged Bicyclo Compounds, Heterocyclic | 1999 |
Bone amyloidoma in a diabetic patient with morbid obesity.
Topics: Amyloidosis; Bone Diseases; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Gl | 1999 |
The effects of a newly synthesized ATP-sensitive potassium channel opener, MJ-355, on blood pressure and myocardial ischemia-reperfusion injury in rats.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; ATP-Bind | 1999 |
Different mechanisms for testosterone-induced relaxation of aorta between normotensive and spontaneously hypertensive rats.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Dose-Response R | 1999 |
The role of oxygen-derived free radicals in augmented relaxations to levcromakalim in the aorta from hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Catalase; Cromakalim; Deferoxamine; Dose-Response Relationship, Drug | 2001 |
The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions.
Topics: Animals; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Bind | 2001 |
Relationship between blood pressure and in vivo action of insulin in type II (non-insulin-dependent) diabetic subjects.
Topics: Antihypertensive Agents; Blood Pressure; C-Peptide; Diabetes Mellitus, Type 2; Diet, Diabetic; Femal | 1992 |
Functional changes in potassium channels in carotid arteries from stroke-prone spontaneously hypertensive rats.
Topics: Animals; Benzopyrans; Carotid Arteries; Cerebrovascular Disorders; Cromakalim; Glyburide; Hypertensi | 1990 |
Hypoglycemia induced by angiotensin-converting enzyme inhibitors in patients with non-insulin-dependent diabetes receiving sulfonylurea therapy.
Topics: Captopril; Diabetes Mellitus, Type 2; Enalapril; Glyburide; Humans; Hypertension; Hypoglycemia; Male | 1990 |