ouabain has been researched along with Hypertension in 534 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 230 (43.07) | 18.7374 |
| 1990's | 131 (24.53) | 18.2507 |
| 2000's | 106 (19.85) | 29.6817 |
| 2010's | 62 (11.61) | 24.3611 |
| 2020's | 5 (0.94) | 2.80 |
| Authors | Studies |
|---|---|
| El-Mallakh, RS; Gao, Y; Hamlyn, J; Roberts, M | 1 |
| Huang, J; Lai, X; Li, J; Pan, Y; Qin, F; Wen, H; Yang, T; Yu, J; Zhong, X | 1 |
| Castro, MM; Couto, GK; Ishikawa, FM; Parente, JM; Rossoni, LV; Tomazelli, CA; Xavier, FE | 1 |
| Hamlyn, JM; Leenen, FHH; Wang, HW | 1 |
| Cao, B; Li, J; Wang, Q; Yue, J; Zheng, M; Zhou, X | 1 |
| Kaaja, RJ; Nicholls, MG | 1 |
| Casanova, P; Citterio, L; Lanzani, C; Manunta, P; Messaggio, E; Simonini, M | 2 |
| Davis, J; Oparil, S | 1 |
| Dong, M; Feng, YM; Hao, JP; Ji, X; Qie, LY; Shi, H; Zhang, CM; Zhang, J | 1 |
| Fürstenwerth, H | 1 |
| Paczula, A; Piecha, G; Wiecek, A | 1 |
| Aileru, AA; Diz, DI; Jeffers, AB; Pulgar, VM; Rashad, HM | 1 |
| Garvin, JL; Gonzalez-Vicente, A | 1 |
| Rossoni, LV; Wenceslau, CF | 1 |
| Khandelia, H; Kopec, W; Loubet, B; Poulsen, H | 1 |
| Axelband, F; Carmona, AK; Dias, J; Ferrão, FM; Lara, LS; Vieyra, A | 1 |
| Guo, C; Liu, M; Ren, Y | 1 |
| Gao, H; Ji, X; Liu, X; Qiu, J; Shen, L; Wang, Y; You, B; Zhao, S | 1 |
| Bianchi, G; Ferrandi, M; Ferrari, P; Manunta, P; Molinari, I; Rastaldi, MP | 1 |
| Al-Bader, M; Ghadhanfar, E; Turcani, M | 1 |
| Couto, GK; Davel, AP; Peres, EC; Rossoni, LV; Wenceslau, CF; Xavier, FE | 1 |
| Ark, M; Aypar, E; Demirtaş, A; Gözübüyük, G; Ozdemir, A; Şahan, G; Turan, NN | 1 |
| Hamlyn, JM; Manunta, P | 3 |
| Takahashi, H | 1 |
| Brioni, E; Casamassima, N; Citterio, L; Delli Carpini, S; Gatti, G; Hamlyn, JM; Lanzani, C; Manunta, P; Messaggio, E; Simonini, M; Zagato, L | 1 |
| Blaustein, MP; Hamlyn, JM | 5 |
| Brioni, E; Casamassima, N; Hamlyn, JM; Lanzani, C; Manunta, P; Messaggio, E; Simonini, M; Tentori, S; Zagato, L | 1 |
| Conner, CD; DuPlessis, M; Ketchem, CJ; Khundmiri, SJ; Lederer, ED; Merchant, M; Murray, RD; Wilkey, D | 1 |
| Andronikashvili, I; Kantaria, N; Pantsulaia, I; Simonia, G | 1 |
| Adrogué, HJ; Madias, NE | 1 |
| Scheiner-Bobis, G; Schoner, W | 3 |
| Alonso, MJ; Beltrán, AE; Briones, AM; Hernanz, R; Martín, A; Salaices, M; Tejerina, T | 1 |
| Alonso, MJ; Padilha, AS; Peçanha, FM; Salaices, M; Vassallo, DV | 1 |
| Blaustein, MP; Chen, L; Hamlyn, JM; Iwamoto, T; Izuka, M; Kinsey, SP; Kotlikoff, MI; Lingrel, JB; Philipson, KD; Raina, H; Song, H; Wier, WG; Zhang, J | 1 |
| Gabor, A; Leenen, FH | 1 |
| Alonso, MJ; Briones, AM; Cogolludo, AL; Padilha, AS; Pérez-Vizcaino, F; Salaices, M; Vassallo, DV | 1 |
| Bianchi, G; Citterio, L; Florio, M; Hamlyn, JM; Kouznetsova, T; Lanzani, C; Manunta, P; Messaggio, E; Modica, R; Staessen, JA; Tripodi, G; Zagato, L | 1 |
| Dean, S; Dostanic-Larson, I; Hou, X; Lingrel, JB; Moseley, AE; Theriault, SF; Van Huysse, JW; Wu, H | 1 |
| Bagrov, AY; Fedorova, OV; Shapiro, JI | 2 |
| Davel, AP; Fukuda, LE; Rossoni, LV; Xavier, FE | 1 |
| Caruso-Neves, C; Gomes-Quintana, E; Landgraf, SS; Lara, LS; Líbano-Soares, JD; Lopes, AG; Queiroz-Madeira, EP; Sudo, RT; Takiya, CM; Wengert, M; Zapata-Sudo, G | 1 |
| Berra-Romani, R; Blaustein, MP; Hamlyn, JM; Izuka, M; Karashima, E; Mauban, JR; Raina, H; Wier, WG; Zhang, J; Zulian, A | 1 |
| Amin, MS; Leenen, FH; Reza, E; Wang, H | 1 |
| Chen, XY; Liu, YF; Xu, RC; Xu, ZW | 1 |
| Brands, MW; Carneiro, FS; Carneiro, ZN; Giachini, FR; Lima, VV; Tostes, RC; Webb, RC | 1 |
| Baryshnikov, SG; Berra-Romani, R; Beskina, O; Blaustein, MP; Golovina, VA; Hamlyn, JM; Mazzocco-Spezzia, A; Papparella, I; Pulina, MV; Zulian, A | 1 |
| Bertorello, AM; Jaitovich, A | 1 |
| Ferrari, P | 1 |
| Yuan, ZY; Zhang, YR | 1 |
| Liu, J; Xie, ZJ | 1 |
| Betlehem, J; Cseh, J; Cziráki, A; Fehér, E; Gaszner, B; Kõszegi, T; Lányi, É; Markó, L; Nagy, G; Sulyok, E; Wittmann, I | 1 |
| Carpini, SD; Casamassima, N; Gatti, G; Hamlyn, JM; Manunta, P; Messaggio, E; Zagato, L | 1 |
| Leenen, FH | 1 |
| Bianchi, G; Citterio, L; Lanzani, C; Manunta, P | 1 |
| Padilha, AS; Siman, FD; Stefanon, I; Vassallo, DV | 1 |
| Funder, JW | 1 |
| Argiolas, G; Bianchi, G; Bracale, M; Brioni, E; Casamassima, N; Glorioso, N; Hamlyn, JM; Lanzani, C; Manunta, P; Messaggio, E; Simonini, M | 1 |
| Ge, H; Jiang, X; Lü, ZR; Ren, YP | 1 |
| Iwamoto, T; Kita, S | 3 |
| Argiolas, G; Bianchi, G; Carpini, SD; Citterio, L; Cusi, D; Ferrandi, M; Ferrari, P; Glorioso, N; Lanzani, C; Macciardi, F; Manunta, P; Messaggio, E; Salvi, E; Staessen, JA; Tripodi, G; Valentini, G | 1 |
| Bacchieri, A; Barton, J; Bianchi, G; Citterio, L; de Leeuw, PW; Dłużniewski, M; Espositi, ED; Ferrari, P; Glorioso, N; Januszewicz, A; Kawecka-Jaszcz, K; Lanzani, C; Manunta, P; Milyagin, V; Nikitin, Y; Souček, M; Staessen, JA; Stolarz-Skrzypek, K; Thijs, L; Timio, M; Tykarski, A; Valentini, G | 1 |
| Davel, AP; Rossoni, LV; Wenceslau, CF; Xavier, FE | 1 |
| Huang, BS; Leenen, FH | 8 |
| Serrão, MP; Silva, E; Soares-da-Silva, P | 1 |
| Betlehem, J; Gaszner, B; Lányi, E; Markó, L; Mérei, A; Molnár, GA; Nagy, G; Németh, K; Szijártó, IA; Wittmann, I | 1 |
| Dostanic, I; Hou, X; Lingrel, JB; Van Huysse, JW; Wu, H | 1 |
| Batista, PR; Padilha, AS; Salaices, M; Siman, FD; Vassallo, DV | 1 |
| Citterio, L; Lanzani, C; Manunta, P | 1 |
| Blaustein, MP; Chen, L; Golovina, VA; Hamlyn, JM; Leenen, FH; Pallone, TL; Van Huysse, JW; Wier, WG; Zhang, J | 1 |
| Lingrel, JB; Loreaux, EL; Lorenz, JN; Oshiro, N | 1 |
| Gupta, S; Liu, J; Malhotra, D; Najjar, SM; Shapiro, JI; Xie, Z; Yan, Y | 1 |
| Abraham, NG; Csongradi, E; Drummond, HA; Gousette, MU; Stec, DE; Storm, MV | 1 |
| Antos, LK; Blaustein, MP; Golovina, VA; Linde, CI | 1 |
| Cui, X; Feng, H; Gao, H; Liu, X; Zhao, S | 1 |
| Davydovs'ka, TL; Dmytrenko, OV; Pobigaĭlo, LS; Radchenko, NV; Sagach, VF; Shapoval, LM; Stepanenko, LH; Vavilova, HL | 1 |
| Kapoor, N; Kaur, G; Mohan, P; Prasad, R; Singh, MJ; Sri Nageswari, K | 1 |
| Alonso, MJ; Barker, LA; Briones, AM; Miguel, M; Rossoni, LV; Salaices, M; Vassallo, DV | 1 |
| Barker, LA; dos Santos, L; Rossoni, LV; Vassallo, DV | 1 |
| Bauer, N; Grünbaum, EG; Hambarchian, N; Kirch, U; Kost, H; Krämer, U; Moeller, H; Müller-Ehmsen, J; Neu, H; Schoner, W; Schweitzer, T; Schwinger, R; Weitkamp, C | 1 |
| Dobesová, Z; Kunes, J; Vokurková, M; Zicha, J | 1 |
| Brooks, DP; Edwards, RM; Pullen, MA | 1 |
| Csermely, P; Pándics, T; Rosta, K; Somogyi, J; Szalay, J; Vér, A | 1 |
| Agalakova, NI; Bagrov, AY; Fedorova, OV; Lakatta, EG; Talan, MI | 1 |
| Alonso, MJ; Balfagón, G; Márquez-Rodas, I; Rossoni, LV; Salaices, M; Vassallo, DV; Xavier, FE | 1 |
| Huang, BS; Leenen, FH; Van Vliet, BN | 1 |
| Huang, BS; Kent, MA; Leenen, FH; Van Huysse, JW | 1 |
| Alonso, MJ; Balfagón, G; Rossoni, LV; Salaices, M; Vassallo, DV; Xavier, FE | 1 |
| Dostanic, I; Lingrel, JB; Lorenz, JN; Paul, RJ; Theriault, S; Van Huysse, JW | 1 |
| Huang, BS; Leenen, FH; Wang, H | 2 |
| Arai, Y; Blaustein, MP; Iwamoto, T; Katsuragi, T; Kita, S; Komuro, I; Wakimoto, K; Yoshida, S; Zhang, J | 1 |
| Danilczyk, U; Penninger, J | 1 |
| Bianchi, G; Ferrari, P; Staessen, JA | 1 |
| Bagrov, AY; Fedorova, OV | 1 |
| Buckalew, VM | 1 |
| Bianchi, G; Ferrandi, M; Ferrari, P; Manunta, P | 1 |
| Bianchi, G; De Tommasi, E; Forleo, C; Guida, P; Hamlyn, JM; Iacoviello, M; Lucarelli, K; Manunta, P; Messaggio, E; Pitzalis, MV; Rizzon, P; Romito, R | 1 |
| Gullans, SR; Haupert, GT; Jensen, RV; Murrell, JR; Randall, JD; Rosoff, J; Zhao, JL | 1 |
| Ge, H; Lui, ZR; Ren, YP | 1 |
| Lü, ZR; Ren, YP | 1 |
| Acceto, R; Bacchieri, A; Bianchi, G; Brand, E; Burnier, M; Celis, H; Citterio, L; de Leeuw, PW; Ferrari, P; Filipovský, J; Fournier, A; Kawecka-Jaszcz, K; Kuznetsova, T; Manunta, P; Nikitin, Y; O'Brien, ET; Redón, J; Staessen, JA; Thijs, L; Valentini, G | 1 |
| Dostanic-Larson, I; Lingrel, JB; Lorenz, JN; Van Huysse, JW | 1 |
| Barassi, P; Bianchi, G; Ferrandi, M; Ferrari, P; Minotti, E; Molinari, I; Torielli, L; Tripodi, G | 1 |
| Ghishan, FK; Kiela, PR; Liu, J; Malhotra, D; Oweis, S; Shapiro, JI; Wu, L; Xie, Z; Zhao, H | 1 |
| Huang, RW; Lü, ZR; Ren, YP | 1 |
| Davenport, L; Fink, GD; Thakali, K; Watts, SW | 1 |
| Danchuk, S; Ianosi-Irimie, M; Kamano, Y; Nogawa, T; Pettit, GR; Puschett, JB; Rabon, E; Vu, H; Wiese, T | 1 |
| Blaustein, MP; Chen, L; Hamilton, BP; Zhang, J | 1 |
| Bianchi, G; Ferrandi, M; Ferrari, P; Valentini, G | 1 |
| Blaustein, MP; Hamilton, BP | 1 |
| Alonso, MJ; Arribas, SM; Briones, AM; González, MC; Rossoni, LV; Salaices, M; Xavier, FE | 1 |
| Babeanu, S; Bianchi, G; Brand, E; Brand-Herrmann, SM; Casiglia, E; Cwynar, M; Filipovský, J; Grodzicki, T; Kawecka-Jaszcz, K; Kuznetsova, T; Nikitin, Y; Peleska, J; Staessen, JA; Stolarz, K; Struijker-Boudier, H; Thijs, L; Tikhonoff, V; Wojciechowska, W | 1 |
| Ferrandi, M; Ferrari, P; Manunta, P; Messaggio, E | 1 |
| Cheung, WJ; El-Shahat, E; Kent, MA; Leenen, FH; Tan, J; Wang, H; White, R | 1 |
| Abe, M; Cowley, AW; Kaldunski, M; Liang, M; O'Connor, P; Roman, RJ | 1 |
| Amanso, AM; Carvalho, CR; Falcochio, D; Moreira, CM; Rossoni, LV; Tanoue, CU; Vassallo, DV; Xavier, FE | 1 |
| Amin, MS; Huang, BS; Leenen, FH | 1 |
| Iwamoto, T | 1 |
| Haddy, FJ | 4 |
| Komiyama, Y; Takahashi, H | 1 |
| Guo, N; Jiang, X; Lü, ZR | 1 |
| Ge, H; Lü, ZR | 1 |
| Bianchi, G; Ferrandi, M; Ferrari, P; Manunta, P; Valentini, G | 1 |
| Noël, F; Quintas, LE; Wibo, M | 1 |
| Citterio, L; Ferrandi, M; Lanzani, C; Manunta, P | 1 |
| Bełtowski, J; Borkowska, E; Marciniak, A; Wójcicka, G | 1 |
| Bianchi, G; Ferrandi, M; Ferrari, P; Molinari, I | 1 |
| Bagrov, AY; Conrady, AO; Kalinkin, AL; Merkulova, NK; Rotari, OP; Shlyakhto, EV; Sviryaev, YV; Zvartau, NE | 1 |
| Blaustein, MP; Hamlyn, JM; Pallone, TL | 1 |
| Alkadhi, K; Alzoubi, K | 1 |
| Epstein, FH | 1 |
| Anderson, DE; Bagrov, AY; Fedorova, OV; Kashkin, VA; Lakatta, EG; Longo, DL; Metzler, JD; Morrell, CH | 1 |
| Bianchi, G; Burnier, M; Casamassima, N; Citterio, L; Hamlyn, JM; Lanzani, C; Maillard, M; Manunta, P; Simonini, M; Stella, P; Tantardini, C | 1 |
| Dostanic-Larson, I; Lasko, V; Lingrel, JB; Loreaux, EL; Lorenz, JN; Paul, RJ; Schnetzer, JR | 1 |
| Ogata, E; Sekine, K; Yamakawa, K | 1 |
| Fujii, J; Seki, A; Suzuki, K; Takayama, Y; Yamaoki, K | 1 |
| Graves, SW; Williams, GH | 1 |
| Cloix, JF; Crabos, M; Delva, P; Henning, G; Meyer, P | 1 |
| Beugras, JP; Cirillo, M; David-Dufilho, M; Devynck, MA; Meyer, P | 1 |
| Baudouin-Legros, M; de Thé, H; Delva, P; Deray, G; Devynck, MA; Meyer, P; Pernollet, MG; Rosenfeld, J; Wauquier, I | 1 |
| Cloix, JF; De Thé, H; Devynck, MA; Elghozi, JL; Kamal, LA; Lacerda-Jacomini, LC; Meyer, P; Pernollet, MG; Rosenfeld, JB | 1 |
| Baudouin-Legros, M; Cloix, JF; Crabos, M; Delva, P; Deray, G; Devynck, MA; Henning, G; Pernollet, MG; Rieu, M; Wauquier, I | 1 |
| Kricka, LJ; Weissberg, PL; West, MJ; Wilkins, MR | 1 |
| Altura, BM; Altura, BT | 1 |
| Hilton, PJ; Jones, RB; Poston, L; Richardson, PJ | 1 |
| Bing, RF; Heagerty, AM; Milner, M; Swales, JD; Thurston, H | 1 |
| Kricka, LJ; Weissberg, PL; Wilkins, MR | 1 |
| Birks, RI; Langlois, S | 1 |
| Cloix, JF; de The, H; Devynck, MA; Kamal, LA; Meyer, P; Pernollet, MG; Rosenfeld, JB | 1 |
| de Thé, H; Devynck, MA; Elghozi, JL; Meyer, P; Pernollet, MG; Rosenfeld, J | 1 |
| Haddy, FJ; Pamnani, MB | 5 |
| Bolli, P; Bühler, FR; Hulthén, UL; Kiowski, W | 2 |
| Cirillo, M; David-Dufilho, M; Devynck, MA | 1 |
| Nordenfelt, I; Ohlsson, O; Sallerfors, B | 1 |
| Dagher, G; Devynck, MA; Garay, RP; Meyer, P; Pernollet, MG | 1 |
| Folkow, B; Göthberg, G; Jandhyala, B | 1 |
| Mulvany, MJ; Nilsson, H; Nyborg, N | 1 |
| Helber, A; Wambach, G | 1 |
| Adragna, N; Bize, I; Canessa, M; Dagher, G; Garay, R; Meyer, P; Solomon, H; Tosteson, DC | 1 |
| Bonting, SL; De Pont, JJ; Schuurmans Stekhoven, FM; Swarts, HG; Thien, TA; Van't Laar, A | 1 |
| Bertrand, E; Dagher, G; Garay, RP; Meyer, P; Nazaret, C | 1 |
| De Mendonca, M; Garay, R; Grichois, ML; Herubel, A; Knorr, A; Meyer, P; Toumi, K | 1 |
| Harlan, DM; Mann, GV | 1 |
| Blaustein, MP; Hamilton, BP; Hamlyn, JM; Kowarski, AA; Levinson, PD; Ringel, R; Schaeffer, J | 1 |
| Cole, CH | 1 |
| Devynck, MA; Meyer, P; Pernollet, MG; Rosenfeld, JB | 1 |
| De The, H; Devynck, MA; Meyer, P; Pernollet, MG; Rosenfeld, JB | 1 |
| Cloix, JF; de The, H; Devynck, MA; Elghozi, JL; Kamal, L; Meyer, P; Pernollet, MG; Rosenfeld, J | 1 |
| Johansen, T; Klitgaard, NA; Pedersen, KE; Rokkedal Nielsen, J | 1 |
| Kojima, I | 1 |
| Canessa, M | 1 |
| Cheung, DW | 1 |
| Bing, RF; Heagerty, AM; Riozzi, A; Swales, JD; Thurston, H | 1 |
| Fleming, WW; Menear, D; Westfall, DP; Wong, SK | 1 |
| Borghetti, A; Montanari, A; Novarini, A; Sani, E; Schianchi, P; Simoni, I | 1 |
| Da Silva, J; Milne, FJ | 1 |
| Ijichi, H; Iyoda, I; Nakagawa, M; Okajima, H; Sasaki, S; Takahashi, H; Takeda, K; Yoshimura, M | 1 |
| Bin Talib, HK; Chipperfield, AR; Semple, PF | 1 |
| Hough, K; Rho, JH | 1 |
| Chien, YW; Zhao, GS | 1 |
| Bramley, PM; Millar, JA; Paulin, JM; Simpson, FO | 1 |
| Gray, HH; Hilton, PJ; Johnson, VE; Poston, L | 1 |
| Morgan, DB; Rubython, J | 1 |
| Slosberg, BN; Wolowyk, MW | 1 |
| Johansen, T; Klitgaard, NA; Nielsen, JR; Pedersen, KE | 4 |
| Brod, J; Hengstenberg, JH; Kleinschmidt, TG; Schaeffer, J | 1 |
| de Estable-Puig, RF; Estable-Puig, JF; Manz, HJ | 1 |
| Bayley, S; Chiodini, P; Dobbs, RJ; Phillips, RJ; Robinson, BF; Wilson, P | 1 |
| Horie, R; Igawa, T; Ikeda, K; Kanbe, T; Kihara, M; Mori, K; Nara, Y; Yamori, Y | 1 |
| Dagher, G; Garay, RP; Hannaert, P; Maridonneau, I; Meyer, P; Nazaret, C | 1 |
| Conklin, DJ; Simon, G; Soong, LB | 1 |
| Ben-Ishay, D; De Mendonca, M; Garay, RP; Grichois, ML; Knorr, A; Meyer, P | 1 |
| Mulvany, MJ | 3 |
| Friedman, SM; McIndoe, RA; Spieckermann, G | 1 |
| Matsuka, H | 1 |
| Ayachi, S; Brown, AM | 1 |
| Corgier, M; Gheyouche, R; Le Fur, G; Uzan, A | 1 |
| Ambrosioni, E; Costa, FV; Magnani, B; Montebugnoli, L; Tartagni, F | 1 |
| Beevers, DG; West, MJ; Woods, KL | 1 |
| Balzan, S; Bartolini, V; Buzzigoli, G; Donato, L; Ghione, S | 1 |
| Bohr, DF; Webb, RC | 2 |
| Ku, DD; Overbeck, HW; Pamnani, MB | 1 |
| Dagher, G; Garay, RP; Meyer, P | 1 |
| Clough, DL; Haddy, FJ; Huot, SJ; Pamnani, MB | 1 |
| Chen, S; Haddy, FJ; Hamlyn, JM; Manunta, P; Pamnani, MB; Yuan, C | 1 |
| Hales, CA; Haupert, GT; Janssens, SP; Kachoris, C; Parker, WL | 1 |
| Gonick, HC; Prins, BA; Purdy, RE; Weiler, EW | 1 |
| Harmsen, E; Huang, BS; Leenen, FH | 1 |
| Bianchi, G; Ferrandi, M; Ferrari, P; Florio, M; Minotti, E; Salardi, S | 2 |
| Deng, LY; Li, JS; Schiffrin, EL | 1 |
| Arii, H; Demura, H; Katsumori, K; Kuroki, H; Maruyama, A; Naruse, K; Naruse, M; Saito, S; Wasada, T; Watanabe, Y | 1 |
| Krasnikova, LT; Mazaev, AV; Vikhert, OA | 1 |
| Chakir, M; Lehoux, S; Lortie, M; Plante, GE | 1 |
| Ferrannini, E; Mattei, P; Natali, A; Salvetti, A; Taddei, S; Virdis, A | 1 |
| Marín, J; Peiró, C; Redondo, J; Rodríguez-Mañas, L; Salaices, M; Sánchez-Ferrer, CF | 1 |
| Golinski, P; Neusser, M; Spieker, C; Tepel, M; Zhu, Z; Zidek, W | 1 |
| Burnard, SL; Head, RJ; Howe, PR; King, RA; McMurchie, EJ; Patten, GS | 1 |
| Amler, E; Burkhard, M; Cester, N; Kotyk, A; Mazzanti, L; Romanini, C; Salvolini, E; Staffolani, R | 1 |
| Hamilton, BP; Hamlyn, JM; Manunta, P; Rogowski, AC | 1 |
| Atrakchi, A; Carlsen, RC; Gray, SD; Pickar, JG | 1 |
| Fort, C; Gomez-Sanchez, CE; Gomez-Sanchez, EP | 1 |
| Amler, E; Cester, N; Kotyk, A; Magnanelli, R; Mazzanti, L; Romanini, C | 1 |
| Gupta, RK; Jelicks, LA | 1 |
| Golinski, P; Holthues, J; Mehring, N; Neusser, M; Tepel, M; Zhu, Z; Zidek, W | 1 |
| Burnard, SL; Head, RJ; Howe, PR; McMurchie, EJ; Patten, GS; Smith, RM | 1 |
| Arribas, S; Balfagón, G; Marín, J; Ponte, A; Salaices, M | 1 |
| Cacciafesta, M; Carlomagno, A; De Angelis, C; Ferri, C; Guidoni, L; Luciani, AM; Rosi, A; Santucci, A; Scuteri, A; Viti, V | 1 |
| Bin Talib, HK; Zicha, J | 1 |
| Goto, A; Hui, C; Nagoshi, H; Sasabe, M; Sugimoto, T; Yagi, N; Yamada, K | 1 |
| Chen, NH; Ding, JH; Wang, YL | 1 |
| Bauer, S; Husseini, S; Raffelsiefer, A; Tepel, M; Zidek, W | 1 |
| Masuyama, Y; Nishio, I; Tsuda, K | 2 |
| Demura, H; Horiba, N; Inagami, T; Kurimoto, F; Naruse, K; Naruse, M; Tamura, M; Tanabe, A; Watanabe, Y; Yoshimoto, T | 1 |
| Bachmann, J; Barenbrock, M; Ganten, D; Rahn, KH; Spieker, C; Tepel, M; Theilmeier, G; Zidek, W | 1 |
| Doris, PA | 3 |
| de Jong, PA; Didden, MA; Hoekstra, MP; Schellekens, A; Vollebergh, JH | 1 |
| Bohen, E; Chen, S; Haddy, FJ; Hamlyn, JM; Manunta, P; Pamnani, MB; Yeun, J; Yuan, CM | 1 |
| Ellstrom, DR; Foster, CD; Honeyman, TW; Scheid, CR | 1 |
| Kazennov, AM; Ogorodnikova, LE | 1 |
| Buzzaccarini, F; Campagnolo, M; Ceolotto, G; Giusto, M; Marzola, M; Mozzato, MG; Pessina, AC; Semplicini, A; Simonella, C | 1 |
| Biagini, G; Cester, N; Mazzanti, L; Pugnaloni, A; Rabini, RA; Romanini, C; Salvolini, E; Staffolani, R | 1 |
| De Toni, R; Hamlyn, JM; Manunta, P; Pavan, E; Pessina, AC; Rossi, G; Semplicini, A | 1 |
| Bailey, RR; Charles, CJ; Lewis, LK; Lynn, KL; Nicholls, MG; Pidgeon, GB; Rademaker, MT; Richards, AM; Yandle, TG | 1 |
| Lombard, JH; Stekiel, WJ | 1 |
| Lewis, LK; Nicholls, MG; Pidgeon, GB; Richards, AM; Yandle, TG | 1 |
| Hamilton, BP; Hamlyn, JM; Manunta, P | 2 |
| Boura, AL; Giles, WB; Leitch, IM; Read, MA; Walters, WA | 1 |
| Blaustein, MP | 1 |
| Alonso, MJ; Hernández, C; Marín, J; Ponte, A; Sánchez-Ferrer, CF | 1 |
| Atarashi, K; Goto, A; Hazama, H; Hirata, Y; Kimura, K; Omata, M; Uehara, Y; Yamada, K | 1 |
| Ensign, A; Graves, SW; Hollenberg, NK; Krep, HH; Lazarus, M; Price, DA; Soszynski, PA | 1 |
| Rashed, SM; Songu-Mize, E; Varner, KJ; Vassallo, DV | 1 |
| Arakawa, K; Ideishi, M; Kinoshita, A; Koga, M; Miura, S; Sakai, T; Sasaguri, M; Shindo, M; Tanaka, H; Tashiro, E | 1 |
| Ando, K; Fujita, T; Shimosawa, T | 1 |
| Budzikowski, AS; Leenen, FH | 1 |
| Husted, RF; Stokes, JB; Takahashi, T | 1 |
| de Wardener, HE | 3 |
| Hara, K; Kimura, Y; Komiyama, Y; Masuda, M; Mori, T; Munakata, M; Murakami, T; Nishimura, N; Okuda, K; Takahashi, H | 1 |
| Goto, A; Omata, M; Yamada, K | 1 |
| Amler, E; Cester, N; Lucarelli, G; Mazzanti, L; Rabini, RA; Salvolini, E; Staffolani, R; Tranquilli, AL; Zolese, G | 1 |
| Bianchi, G; Cerri, A; Fedrizzi, G; Ferrari, P; Gobbini, M; Melloni, P; Quadri, L; Sputore, S; Torri, M | 1 |
| Amaral, SM; Rossoni, LV; Songu-Mize, E; Vassallo, DV | 1 |
| Galajada, P; Lichardus, B; Martinka, E; Mokan, M; Ochodnicky, M; Straka, S | 1 |
| Angulo, J; Llergo, JL; Marín, J; Peiró, C; Rodríguez-Mañas, L; Sánchez-Ferrer, CF | 1 |
| Bianchi, G | 1 |
| Budzikowski, AS; Huang, BS; Leenen, FH | 1 |
| Fukuo, K; Hirotani, A; Kitano, S; Morimoto, S; Nakahashi, T; Nishibe, A; Ogihara, T; Yasuda, O | 1 |
| Goto, A; Yamada, K | 2 |
| Anderson, DE; Bagrov, AY; Fedorova, OV | 1 |
| Hong, JH; Hur, GM; Hwang, BD; Jeon, JR; Kim, JB; Lee, JH; Lim, K; Seok, JH | 1 |
| Lu, Z; Wang, H; Yuan, W | 1 |
| Leenen, FH; Veerasingham, SJ | 1 |
| Bianchi, G; Ferrandi, M; Ferrari, P; Melloni, P; Minotti, E; Padoani, G; Torielli, L; Tripodi, G | 1 |
| Gonick, HC; Khalil-Manesh, F; Prins, BA; Purdy, RE; Sensharma, DK; Weiler, EW | 1 |
| Alvarez de Sotomayor, M; Herrera, MD; Marhuenda, E; Pérez-Guerrero, C | 1 |
| Arumanayagam, M; Rogers, M | 1 |
| Bianchi, G; Ciurlino, D; Cusi, D; Ferrandi, M; Hamlyn, JM; Manunta, P; Rivera, R; Stella, P | 1 |
| Buralli, S; Ghiadoni, L; Salvetti, A; Taddei, S; Virdis, A | 1 |
| Huang, BS; Kudlac, M; Kumarathasan, R; Leenen, FH | 1 |
| Adarichev, VA; Devlin, AM; Dominiczak, AF; Hamet, P; Maximova, NV; Orlov, SN; Postnov, YV; Sun, YL; Tremblay, J | 1 |
| Marín, J; Redondo, J | 1 |
| Bezrukov, VV; Dubileĭ, TO; Rushkevych, IuIe | 1 |
| Briones, A; Manso, AM; Marín, J; Pacheco, ME; Redondo, J; Rodríguez-Martínez, MA; Salaices, M | 1 |
| Leenen, FH; Vahid-Ansari, F; Veerasingham, SJ | 1 |
| Dalton, GR; Evans, SJ; Levi, AJ | 1 |
| Dong, XH; Hirose, S; Komiyama, Y; Kosaka, C; Masaki, H; Masuda, M; Nishimura, N; Takahashi, H | 1 |
| Alfazema, L; Dawnay, A; Harwood, S; Perrett, D | 1 |
| Lu, ZR; Wang, H; Yuan, WQ | 1 |
| Schoner, W | 2 |
| Graves, SW; Hollenberg, NK; Markides, KE | 1 |
| Goecke, IA; Irribarra, V; Marusic, ET; Michea, L | 1 |
| Leenen, FH; Zhang, J | 1 |
| Huang, BS; Leenen, FH; Van Huysse, J; White, R; Zhao, X | 1 |
| Agalakova, NI; Bagrov, AY; Fedorova, OV; Kolodkin, NI; Lakatta, EG | 1 |
| Ando, K; Fujita, T; Omi, N; Shimosawa, T; Takahashi, K | 1 |
| Aileru, AA; De Albuquerque, A; Hamilton, MJ; Hamlyn, JM; Manunta, P; Shah, JR; Weinreich, D | 1 |
| Carr, F; Dobesová, Z; Dominiczak, AF; Kunes, J; McBride, MW; Negrin, CD; Vokurková, M; Zicha, J | 1 |
| Akintürk, IH; Hehrlein, FW; Jäger, H; Scheiner-Bobis, G; Wozniak, G | 1 |
| Pinto, VD; Rossoni, LV; Vassallo, DV | 1 |
| Dang, C; Lu, Z; Tian, G | 1 |
| Deng, AY; Dutil, J; Hamet, P; Orlov, SN | 1 |
| Lu, Z; Ren, H; Wang, H; Yuan, W; Yuan, Y | 1 |
| Alonso, MJ; Marín, J; Rossoni, LV; Salaices, M; Vassallo, DV | 1 |
| Hamet, P; Orlov, SN; Taurin, S | 1 |
| Edmondson, RP; Hilton, PJ; Jones, NF; Thomas, RD | 1 |
| Biol, MC; Sassard, J; Vincent, M | 1 |
| Clough, DL; Haddy, FJ; Pamnani, MB | 2 |
| Friedman, SM; Nakashima, M | 2 |
| Gnüchtel, U; Nitschkoff, S; Wallrabe, D | 1 |
| Barrillon, A; Grand, A | 1 |
| Horie, R; Nara, Y; Ohtaka, M; Yamori, Y | 1 |
| Brown, AM; Saum, WR; Tuley, FH | 1 |
| Adler, AM; Orolov, SN; Postnov, IuV; Shevchenko, AS; Sidorskiĭ, AL | 1 |
| Orlov, SN; Postnov, IuV; Shevchenko, AS | 1 |
| Bianchi, G; Ferrario, RG; Foulkes, R; Salvati, P | 1 |
| Buckley, JP; Chelly, JE; Doursout, MF; Liang, YY | 1 |
| Higuchi, M; Miyagi, H; Moromizato, H; Nakayama, M; Sakanashi, M | 2 |
| Fujito, K; Koide, H; Numahata, H; Yokomatsu, M | 1 |
| Husseini, S; Tepel, M; Wischniowski, H; Zidek, W | 1 |
| Uchiyama, M | 1 |
| Dobesová, Z; Klír, P; Kren, V; Kunes, J; Pravenec, M; Talib, HK; Zicha, J | 1 |
| Kojima, T; Sekihara, H; Yazaki, Y | 1 |
| Rüegg, UT | 1 |
| Talib, HK; Zicha, J | 1 |
| Ikeda, M; Miyamori, I; Morise, T; Okamoto, S; Takeda, R | 1 |
| Falase, AO; Lawal, SO; Okunade, WG; Olorunsogo, OO | 1 |
| Ferrandi, M; Ferrari, P; Hanozet, GM; Parenti, P; Villa, M | 1 |
| Goh, CR; Oh, VM; Taylor, EA | 1 |
| Hashimoto, T; Kaguchi, Y; Kuriyama, S; Nakamura, K; Sakai, O | 1 |
| Kimura, K; Masuyama, Y; Nishio, I; Shima, H; Tsuda, K | 1 |
| Goto, A; Hui, C; Sugimoto, T; Yagi, N; Yamada, K | 1 |
| Songu-Mize, E | 1 |
| Aloamaka, CP; Ebeigbe, AB; Obiefuna, PC; Sofola, OA | 1 |
| Bin Talib, HK; Duhm, J; Zicha, J | 1 |
| Biagiarelli, B; Canestrari, F; De Crescentini, S; Galli, F; Gheller, G | 1 |
| Akabane, S; Ashida, T; Kawano, Y; Kuramochi, M; Omae, T; Yoshimi, H | 1 |
| Orlov, SN; Pokudin, NI; Postnov, YV | 1 |
| Prabhakaran, VM; Sampson, CA; Vasdev, S | 1 |
| Barlow, GK; Berry, TD; Hasstedt, SJ; Hopkins, PN; Hunt, SC; Kuida, H; Stults, BM; Williams, RR; Wu, LL | 1 |
| Heller, J; Janata, J; Kamarádová, S | 1 |
| Gnüchtel, U; Gross, V; Grossmann, M | 1 |
| Alpert, BS; Songu-Mize, E; Willey, ES | 1 |
| Devynck, MA; Le Quan Sang, KH; Meyer, P; Pernollet, MG | 1 |
| Hasegawa, T; Iimura, O; Kikuchi, K; Kobayakawa, H; Komura, H; Nishimura, M; Nozawa, A; Yamaji, I | 1 |
| Clough, DL; Haddy, FJ; Pamnani, MB; Whitehorn, WV | 1 |
| Ambrosioni, E; Borghi, C; Boschi, S; Costa, FV; deVries, D; Lu, ZR; Munarini, A | 1 |
| Bracchino, P; Cavaletto, M; Ferrero, P; Giunta, C; Pessione, E; Pizzuto, M | 1 |
| Comte, L; Drüeke, T; Hennessen, U; Lacour, B; McCarron, DA; Steuf, MC | 1 |
| Ang, LM; Oh, VM; Taylor, EA | 1 |
| Goto, A; Ishii, M; Sugimoto, T; Yamada, K | 1 |
| Buckley, JP; Chelly, JE; Doursout, MF; Lawrence, C; Liang, YY; Wouters, P | 1 |
| Duhm, J; Zicha, J | 1 |
| De Mendonça, M; Garthoff, B; Kazda, S; Knorr, A; Morich, F | 1 |
| De Cree, J; Demoen, B; Leempoels, J; Verhaegen, H | 1 |
| Orlov, SN; Postnov, YV | 1 |
| Aranyi, Z; Czinner, A; Koltai, G | 2 |
| Aviv, A; Hopp, L; Khalil, F; Kino, M; Searle, BM; Tamura, H; Tokushige, A | 2 |
| Oh, VM; Taylor, EA | 1 |
| Fukuzaki, H; Furuta, Y; Kariya, K; Saito, K; Sano, H; Yamanishi, J | 1 |
| Chimori, K; Kosaka, J; Miura, K; Miyazaki, S; Sakanaka, A; Yasuda, K | 1 |
| Friedman, SM; McIndoe, RA; Tanaka, M | 1 |
| Fineberg, NS; Smith, JB; Wade, MB; Weinberger, MH | 5 |
| de Mendonça, M; Devynck, MA; Grichois, ML; Meyer, P; Pernollet, MG; Wauquier, I | 1 |
| Engel, CR; Simon, G | 1 |
| Kuske, R; Moreth, K; Renner, D; Schoner, W; Wizemann, V | 1 |
| Ashihara, T; Imaizumi, T; Nakamura, M; Takeshita, A; Yamamoto, K | 1 |
| Aguilera, MT; Coca, A; De la Sierra, A; Urbano Márquez, A | 1 |
| Mansy, H; Thomas, TH; Wilkinson, R | 1 |
| Humphries, KH; Nowaczynski, W; Pudek, MR; Seccombe, DW | 1 |
| Garay, RP; Senn, N | 1 |
| Masuyama, Y; Shima, H; Tsuda, K; Tsuda, S | 1 |
| Aperia, A; Bertorello, A; Fukuda, Y; Melzi, ML; Muldin, I; Sereni, F | 1 |
| Chimori, K; Dodo, S; Goi, R; Goto, S; Hayashi, H; Izai, M; Miura, K; Miyazaki, S; Yasuda, K | 1 |
| Balzan, S; Biver, P; Fantoni, M; Genovesi-Ebert, A; Ghione, S; Montali, U | 1 |
| Capra, C; Degan, M; Delva, P; Fallo, F; Lechi, A; Lechi, C; Mantero, F; Menegazzi, M; Steele, A | 1 |
| Abitbol, JP; Garay, R; Girerd, X; Hannaert, P; Laurent, S; Safar, M | 1 |
| Düsing, R; Freitag, T; Glänzer, K; Kramer, HJ; Krück, F; Schlebusch, H; Schönfeld, J; Sorger, M | 1 |
| Cloix, JF; Crabos, M; Devynck, MA; Elghozi, JL; Henning, G; Kamal, LA; Lacerda-Jacomini, LC; Meyer, P; Pernollet, MG; Rosenfeld, JB | 1 |
| Lamb, FS; Myers, JH; Webb, RC | 1 |
| Pedrinelli, R; Salvetti, A; Taddei, S | 1 |
| Abel, ED; Harker, M; Ng, LL | 1 |
| Boero, R; Deabate, MC; Guarena, C; Piccoli, G; Quarello, F; Rolando, B; Rosati, C | 1 |
| Arosio, E; Delva, P; Guzzo, P; Lechi, A; Lechi, C; Sinigaglia, D; Steele, A | 1 |
| Ijichi, H; Ikegaki, I; Matsuzawa, M; Okabayashi, H; Suga, K; Takahashi, H; Yoshimura, M | 1 |
| Devynck, MA; Grichois, ML; Meyer, P; Pernollet, MG; Wauquier, I | 1 |
| Del Greco, F; Finn, M; Quintanilla, AP; Weffer, MI | 1 |
| Alaghband-Zadeh, J; de Wardener, HE; Holland, S; MacGregor, GA; Millett, J | 1 |
| Bryant, HJ; Haddy, FJ; Pamnani, MB | 1 |
| Kelly, RA | 2 |
| Cloix, JF; Crabos, M; Grichois, ML; Meyer, P | 1 |
| Ibata, Y; Ijichi, H; Ikegaki, I; Matsuzawa, M; Murakami, S; Okabayashi, H; Okamura, H; Suga, K; Takahashi, H; Yoshimura, M | 1 |
| Masuyama, Y; Nishio, I; Tsuda, K; Tsuda, S | 1 |
| Chen, CC; Lin-Shiau, SY | 1 |
| Hasegawa, T; Kumahara, Y; Masugi, F; Ogihara, T | 2 |
| Magargal, WW; Overbeck, HW; Shikuma, R; Wallick, ET | 1 |
| Boero, R; Deabate, MC; Forneris, G; Guarena, C; Piccoli, G; Quarello, F; Rosati, C | 1 |
| Ashen, MD; Forrest, B; Hamlyn, JM; Rogowski, AC; White, RJ | 1 |
| Maling, TJ; Siebers, RW | 1 |
| Moura, AM; Worcel, M | 1 |
| Gonick, H; Khalil-Manesh, F; Weiler, E | 1 |
| Kimura, S; Meguro, Y; Miura, Y; Noshiro, T; Ohashi, H; Sano, N; Sugawara, T; Takahashi, M; Toriyabe, S; Watanabe, H | 1 |
| Cloix, JF; Devynck, MA; Grichois, ML; Guicheney, P; Meyer, P; Pernollet, MG | 1 |
| Aoki, K; Honma, C; Kikuchi, K; Kobayakawa, H; Kudoh, C; Nishimura, M; Nozawa, A; Sakamoto, T; Shimazaki, M; Yamamoto, M | 1 |
| Daman Willems, CE; Dillon, MJ; Shah, V; Uchiyama, M | 1 |
| Cloix, JF; Devynck, MA; Henning, G; Meyer, P; Pernollet, MG; Wainer, IW | 1 |
| Akera, T; Fink, GD; Nirasawa, Y; Temma, K | 1 |
| Kravtsov, GM; Postnov, IuV; Postnova, NA | 1 |
| Müller, S; Walter, U | 1 |
| Brent, D; Gault, MH; Johnson, E; Longerich, L; Vasdev, S | 1 |
| Hasegawa, T; Imai, N; Kumahara, Y; Masugi, F; Nagano, M; Ogihara, T; Tabuchi, Y | 1 |
| Fukuzaki, H; Furuta, Y; Okishio, T; Saito, K; Sano, H | 1 |
| Hilton, PJ | 3 |
| Hasegawa, T; Higashimori, K; Kumahara, K; Masugi, F; Nagano, M; Ogihara, T; Terano, Y; Tomii, A | 1 |
| Del Greco, F; Koh, H; Primera, MI; Quintanilla, AP; Rahman, M | 1 |
| Allen, JC; Kahn, AM; Navran, SS | 1 |
| Kuske, R; Moreth, K; Renner, D; Schoner, W | 1 |
| Gless, KH; Hunstein, W; Schaz, K; Schütz, V; Sütterlin, U | 1 |
| Jest, P; Johansen, T; Klitgaard, NA; Nielsen, JR; Pedersen, KE | 1 |
| Bing, RF; Brand, SC; Heagerty, AM; Riozzi, A; Swales, JD; Thurston, H | 1 |
| Deray, G; Devynck, MA; Meyer, P; Pernollet, MG; Rosenfeld, J; Touam, A; Zingraff, J | 1 |
| Graziadei, L; Pedrinelli, R; Salvetti, A; Taddei, S | 1 |
| Cloix, JF; Crabos, M; Meyer, P | 1 |
| Roulston, JE; Traill, K; Wathen, CG | 1 |
| Abe, K; Kasai, Y; Kohzuki, M; Masugi, F; Omata, K; Sato, M; Takeuchi, K; Tanno, M; Yasujima, M; Yoshinaga, K | 1 |
| Diez, J; Garay, RP; Hannaert, P | 1 |
| Moreth, K; Renner, D; Schoner, W | 1 |
| Berman, MA; Chalew, SA; Hamilton, BP; Hamlyn, JM; Pinkas, GA; Ringel, RE | 1 |
| Bonadonna, G; Corradini, P; Delva, P; Lechi, A; Lechi, C; Polignano, R | 1 |
| Cloix, JF; Crabos, M; Grichois, ML; Guicheney, P; Meyer, P | 1 |
| de Mendonça, M; Devynck, MA; Garay, RP; Grichois, ML; Meyer, P; Pernollet, MG; Thormann, B; Wauquier, I | 1 |
| Iwasaki, T; Kawai, Y; Miyata, S; Morita, S; Nagai, K | 1 |
| Halpern, W; Osol, G | 1 |
| Aviv, A; Hopp, L; Kuriyama, S; Lasker, N; Tamura, H | 1 |
| Hunt, SC; Stults, BM; Williams, RR; Wu, LL | 1 |
| Bruner, CA; Fink, GD; Mangiapane, ML; Webb, RC | 1 |
| Mir, MA; Narayanan, G; Newcombe, R; Spurlock, G; Weeks, S | 1 |
| Fukuzaki, H; Hattori, K; Hirouchi, H; Omatsu, T; Saito, K; Sano, H | 1 |
| Mattiasson, I; Ohlin, H | 1 |
| Chiba, S; Katsuyama, Y; Tada, A; Tsukada, M; Zenda, H | 1 |
| Kjeldsen, K; Nørgaard, A | 1 |
| Kjeldsen, K | 1 |
| Baudouin-Legros, M; Guicheney, P; Meyer, P; Valtier, D | 1 |
| Buckalew, VM; Campbell, WG; Morris, M; Rauch, AL | 1 |
| Ito, H; Kwan, CY; Murakami, M; Seo, Y; Watari, H | 1 |
| Bealer, SL; Caldwell, RW; Songu-Mize, E | 1 |
| Aviv, A; Hopp, L; Kino, M; Searle, BM; Tamura, H; Tokushige, A | 2 |
| Jones, JC; MacGregor, GA; Markandu, ND; Sagnella, GA; Shore, AC | 1 |
| Cheung, HC; Ong, RL | 1 |
| Gray, HH; Hilton, PJ; Richardson, PJ | 1 |
| Bruner, CA; Jokelainen, PT; Myers, JH; Sing, CF; Webb, RC | 1 |
| Arosio, E; Bonadonna, G; Corradini, P; Covi, G; de Togni, P; Lechi, A; Lechi, C; Polignano, R; Sinigaglia, D | 1 |
| Hall, JL; Lamb, FS; Mecca, TE; Webb, RC | 1 |
| Jones, AW; Magliola, L; McMahon, EG | 1 |
| Major, TC; Moreland, RS; Webb, RC | 1 |
| Aronson, JK; Boon, NA; Grahame-Smith, DG; Harper, C | 1 |
| Boero, R; Guarena, C; Piccoli, G; Quarello, F | 1 |
| Borghi, L; Montanari, A; Novarini, A; Sani, E; Schianchi, P; Simoni, I | 1 |
| Ely, D; Folkow, B; Friberg, P; Karlström, G; Nilsson, H | 1 |
| Deray, G; Devynck, MA; Meyer, P; Pernollet, MG; Rieu, M | 1 |
| Adragna, NC; Lauf, PK; Perkins, CM | 1 |
| Godon, JP; Krzesinski, JM; Rorive, GL | 1 |
| Cloix, JF; Crabos, M; Deray, G; Devynck, MA; Meyer, P; Pernollet, MG; Rieu, M; Wainer, IW | 1 |
| Beynon, GW; Jones, JC; MacGregor, GA; Markandu, ND; Sagnella, GA; Shore, AC | 1 |
| Battaner, E; García Pérez, J; Getino, MA; Marrero, F; Martín Vasallo, P | 1 |
| Garay, RP; Nazaret, C | 1 |
| Marwood, JF; Monaghan, JC; Stokes, GS | 1 |
| Bravo, EL; Gardner, JD; Lapey, A; Simopoulos, P | 1 |
| Kuchii, M; Kurahashi, K; Shibata, S | 1 |
| Fiorentini, C; Guazzi, M; Magrini, F; Polese, A | 1 |
| Abelmann, WH; Kumar, R; Yankopoulos, NA | 1 |
| Arbeit, S; Delman, AJ; Escher, JW | 1 |
| McArdle, B; Schott, GD | 1 |
| Schoffeniels, E | 1 |
| Di Lieto, M; Ettinger, S; Gould, L; Lyon, AF; McGinn, FX | 1 |
| Ducloux, G; Fossati, G; Wache, F; Warembourg, H | 1 |
| Braunwald, E; Covell, JW; Maroko, PR; Ross, J; Watanabe, T | 1 |
| Abelmann, WH; Adler, LN; Federici, EE; Kawai, C; Yankopoulos, NA | 1 |
88 review(s) available for ouabain and Hypertension
| Article | Year |
|---|---|
Sodium pumps, ouabain and aldosterone in the brain: A neuromodulatory pathway underlying salt-sensitive hypertension and heart failure.
Topics: Aldosterone; Animals; Brain; Heart Failure; Humans; Hypertension; Ouabain; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase | 2020 |
Does the hormone "endogenous ouabain" exist in the human circulation?
Topics: Blood Pressure; Cardiotonic Agents; Dissent and Disputes; Female; Heart Failure; Humans; Hypertension; Ouabain; Pregnancy; Quackery; Renal Insufficiency; Wedge Argument | 2018 |
Endogenous Ouabain and Related Genes in the Translation from Hypertension to Renal Diseases.
Topics: Animals; Calmodulin-Binding Proteins; Humans; Hypertension; Kidney Diseases; Ouabain | 2018 |
Novel Medical Treatments for Hypertension and Related Comorbidities.
Topics: Aminopeptidases; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Endothelin Receptor Antagonists; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Ouabain; ras Proteins; Receptors, Vasoactive Intestinal Peptide; Sodium-Hydrogen Exchanger 3; Vaccines | 2018 |
Cardiotonic Steroids-A Possible Link Between High-Salt Diet and Organ Damage.
Topics: Animals; Blood Pressure; Cardiac Glycosides; Humans; Hypertension; Ouabain; Risk Factors; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase | 2019 |
Endogenous cardiotonic steroids in kidney failure: a review and an hypothesis.
Topics: Bufanolides; Cardiac Glycosides; Disease Progression; Ganglia, Sympathetic; Humans; Hypertension; Kidney Failure, Chronic; Neuronal Plasticity; Ouabain; Renal Insufficiency, Chronic; Sympathetic Nervous System | 2015 |
[Laboratory Medicine Learned Through Research on the Pathogenesis of Hypertension].
Topics: Animals; Baroreflex; Central Nervous System; Digitalis; Epithelial Sodium Channels; Humans; Hyperaldosteronism; Hypertension; Kidney; Medical Laboratory Science; Obesity; Ouabain; Renin-Angiotensin System; Research; Sodium, Dietary; Sympathetic Nervous System | 2015 |
Endogenous Ouabain: Recent Advances and Controversies.
Topics: Adrenal Cortex; Animals; Blood Pressure Determination; Cardiovascular Diseases; Female; Humans; Hypertension; Kidney Diseases; Male; Mice; Needs Assessment; Ouabain; Sodium-Potassium-Exchanging ATPase | 2016 |
Sodium and potassium in the pathogenesis of hypertension: focus on the brain.
Topics: Aldosterone; Angiotensin II; Animals; Brain; Humans; Hypertension; Ouabain; Oxidative Stress; Potassium; Renin-Angiotensin System; Sodium; Sympathetic Nervous System; Vascular Resistance | 2017 |
Role of endogenous cardiotonic steroids in sodium homeostasis.
Topics: Adrenal Cortex; Animals; Bufanolides; Cardiac Glycosides; Cardiotonic Agents; Digoxin; Homeostasis; Humans; Hypertension; Kidney Tubules, Proximal; Natriuresis; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase; Vasoconstrictor Agents | 2008 |
The pump, the exchanger, and endogenous ouabain: signaling mechanisms that link salt retention to hypertension.
Topics: Animals; Disease Models, Animal; Humans; Hypertension; Ouabain; Signal Transduction; Sodium Chloride; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase | 2009 |
[Endogenous cardioactive steroids--a new class of steroid hormones].
Topics: Amphibians; Animals; Atrial Natriuretic Factor; Bufanolides; Cardenolides; Hormones; Humans; Hypertension; Mammals; Ouabain; Plant Growth Regulators; Saponins; Sodium Chloride, Dietary; Steroids | 2009 |
Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targets.
Topics: Animals; Blood Pressure; Bufanolides; Cardiac Glycosides; Cardiotonic Agents; Diabetes Mellitus; Enzyme Inhibitors; Female; Heart Failure; Humans; Hypertension; Ouabain; Pre-Eclampsia; Pregnancy; Signal Transduction; Sodium-Potassium-Exchanging ATPase | 2009 |
Salt, Na+,K+-ATPase and hypertension.
Topics: Animals; Humans; Hypertension; Muscle, Smooth, Vascular; Ouabain; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; Vascular Resistance | 2010 |
Rostafuroxin: an ouabain-inhibitor counteracting specific forms of hypertension.
Topics: Androstanols; Animals; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Clinical Trials, Phase II as Topic; Disease Models, Animal; ErbB Receptors; Humans; Hypertension; Kidney; Mutation; Ouabain; Polymorphism, Genetic; Signal Transduction; Sodium; Sodium-Potassium-Exchanging ATPase; src-Family Kinases | 2010 |
The sodium pump and cardiotonic steroids-induced signal transduction protein kinases and calcium-signaling microdomain in regulation of transporter trafficking.
Topics: Animals; Bufanolides; Calcium Signaling; Humans; Hypertension; Kidney Tubules, Proximal; Ouabain; Protein Kinases; Protein Transport; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 2010 |
Signaling mechanisms that link salt retention to hypertension: endogenous ouabain, the Na(+) pump, the Na(+)/Ca(2+) exchanger and TRPC proteins.
Topics: Adrenal Cortex; Animals; Blood Pressure; Calcium Signaling; Cardiotonic Agents; Digoxin; Endothelium, Vascular; Humans; Hypertension; Ion Transport; Kidney; Myocytes, Smooth Muscle; Ouabain; Pituitary Gland; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; TRPC Cation Channels | 2010 |
Endogenous ouabain in renal Na(+) handling and related diseases.
Topics: Adrenal Glands; Angiotensin II; Animals; Cell Proliferation; Diuretics; Drosophila; Epinephrine; Heart Failure; Homeostasis; Humans; Hypertension; Kidney; Myocytes, Cardiac; Myocytes, Smooth Muscle; Ouabain; Renal Insufficiency; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Vasoconstriction | 2010 |
The central role of the brain aldosterone-"ouabain" pathway in salt-sensitive hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Choroid Plexus; Ependyma; Epithelial Sodium Channels; Humans; Hypertension; Ion Transport; Kidney; Membrane Potentials; Neurons; Ouabain; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Sodium; Water-Electrolyte Balance | 2010 |
Endogenous cardiotonic steroids and salt-sensitive hypertension.
Topics: Amphibians; Animals; Biological Transport; Blood Pressure; Fibrosis; Humans; Hypertension; Kidney; Kidney Diseases; Ouabain; Rodentia; Sodium; Sodium-Potassium-Exchanging ATPase | 2010 |
Genetics of primary hypertension: the clinical impact of adducin polymorphisms.
Topics: Animals; Blood Pressure; Calmodulin-Binding Proteins; Diuretics; Humans; Hypertension; Kidney Tubules; Ouabain; Polymorphism, Genetic; Sodium | 2010 |
Aldosterone, hypertension and heart failure: insights from clinical trials.
Topics: Aldosterone; Animals; Anticholesteremic Agents; Atorvastatin; Clinical Trials as Topic; Dihydrotestosterone; Drug Therapy, Combination; Enzyme Inhibitors; Female; Heart Failure; Heptanoic Acids; Humans; Hydrocortisone; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Mice; Mineralocorticoid Receptor Antagonists; Ouabain; Pyrroles; Quinolines; Rats; Spironolactone | 2010 |
Endogenous ouabain: a link between sodium intake and hypertension.
Topics: Aldosterone; Diet; Humans; Hypertension; Nutritional Status; Ouabain; Receptors, Cell Surface; Risk Factors; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary | 2011 |
[Mechanisms for linking high salt intake to vascular tone: role of Na(+) pump and Na(+)/Ca²(+) exchanger coupling].
Topics: Animals; Calcium; Calcium Signaling; Cardiac Glycosides; Cytosol; Humans; Hypertension; Mice; Muscle Tonus; Muscle, Smooth, Vascular; Ouabain; Rats; Sodium; Sodium Chloride, Dietary; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase | 2010 |
Mineralocorticoid actions in the brain and hypertension.
Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Brain; Cerebrospinal Fluid; Cytochrome P-450 CYP11B2; Epithelial Sodium Channels; Humans; Hypertension; Mineralocorticoids; Ouabain; Pressoreceptors; Renin-Angiotensin System | 2011 |
Hypertensive effects of the iv administration of picomoles of ouabain.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium; Cardiotonic Agents; Central Nervous System; Humans; Hypertension; Injections, Intravenous; Norepinephrine; Ouabain; Peptidyl-Dipeptidase A; Rats; Renin-Angiotensin System; Sodium-Potassium-Exchanging ATPase | 2011 |
Polymorphisms, hypertension and thiazide diuretics.
Topics: Biomarkers, Pharmacological; Calmodulin-Binding Proteins; Diuretics; Genetic Association Studies; Genome-Wide Association Study; Humans; Hydrochlorothiazide; Hypertension; Ouabain; Polymorphism, Genetic | 2011 |
How NaCl raises blood pressure: a new paradigm for the pathogenesis of salt-dependent hypertension.
Topics: Animals; Cardiotonic Agents; Female; Humans; Hypertension; Hypothalamus; Male; Mice; Ouabain; Pregnancy; Rats; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; Sympathetic Nervous System | 2012 |
[Functional interaction between Na(+)/Ca(2+) exchanger and sodium-transporting proteins in plasma membrane microdomains].
Topics: Calcium Signaling; Hypertension; Membrane Microdomains; Muscle Tonus; Muscle, Smooth, Vascular; Ouabain; Sodium-Calcium Exchanger | 2012 |
Salt sensitivity, endogenous ouabain and hypertension.
Topics: Animals; Blood Pressure; Brain; Homeostasis; Humans; Hypertension; Ouabain; Sodium Chloride | 2013 |
[New steroid hormone family: endogenous cardiac glycosides and their role in physiologic and pathologic conditions].
Topics: Cardiac Glycosides; Gene Expression Regulation; Heart Failure; Hormones; Humans; Hypertension; Ouabain; Signal Transduction; Sodium-Potassium-Exchanging ATPase | 2004 |
Adducin polymorphism: detection and impact on hypertension and related disorders.
Topics: Animals; Calmodulin-Binding Proteins; Cardiovascular Diseases; Humans; Hypertension; Kidney Diseases; Ouabain; Polymorphism, Genetic | 2005 |
Cardenolide and bufadienolide ligands of the sodium pump. How they work together in NaCl sensitive hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Bufanolides; Cardenolides; Humans; Hypertension; Ligands; Ouabain; Rats; Rats, Inbred Dahl; Renin-Angiotensin System; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 2005 |
Endogenous digitalis-like factors. An historical overview.
Topics: Animals; Cardenolides; Digitalis Glycosides; Digoxin; History, 21st Century; Humans; Hypertension; Natriuretic Agents; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase | 2005 |
The endogenous ouabain: molecular basis of its role in hypertension and cardiovascular complications.
Topics: Animals; Blood Pressure; Humans; Hypertension; Ouabain; Rats; Rats, Inbred SHR; Risk Factors; Sodium Chloride | 2005 |
[A novel hormone found in circulation--endogenous ouabain].
Topics: Adrenal Cortex; Animals; Antibodies; Humans; Hypertension; Nephrotic Syndrome; Ouabain; Sodium-Potassium-Exchanging ATPase | 2005 |
Ouabain antagonists as antihypertensive agents.
Topics: Androstanols; Animals; Antihypertensive Agents; Humans; Hypertension; Ouabain; Rats; Rats, Inbred SHR; Sodium-Potassium-Exchanging ATPase | 2005 |
How does salt retention raise blood pressure?
Topics: Animals; Blood Pressure; Humans; Hypertension; Kidney; Ouabain; Sodium Chloride; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; Water-Electrolyte Imbalance | 2006 |
Rostafuroxin: an ouabain antagonist that corrects renal and vascular Na+-K+- ATPase alterations in ouabain and adducin-dependent hypertension.
Topics: Androstanols; Animals; Antihypertensive Agents; Blood Vessels; Calmodulin-Binding Proteins; Humans; Hypertension; Kidney; Ouabain; Sodium-Potassium-Exchanging ATPase; Treatment Outcome | 2006 |
Sodium excretion as a modulator of genetic associations with cardiovascular phenotypes in the European Project on Genes in Hypertension.
Topics: Blood Pressure; Calmodulin-Binding Proteins; Cytochrome P-450 CYP11B2; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Ouabain; Peptidyl-Dipeptidase A; Phenotype; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Sodium | 2006 |
A new antihypertensive agent that antagonizes the prohypertensive effect of endogenous ouabain and adducin.
Topics: Androstanols; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Humans; Hypertension; Ouabain; Risk Factors; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 2006 |
Hypertension, Na+/Ca2+ exchanger, and Na+, K+-ATPase.
Topics: Androstanols; Aniline Compounds; Animals; Blood Pressure; Calcium; Cardiac Glycosides; Cardiovascular System; Cell Membrane; Humans; Hypertension; Kidney; Muscle, Smooth, Vascular; Ouabain; Phenyl Ethers; Protein Binding; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary; Vasoconstriction | 2006 |
The central role of the brain in salt-sensitive hypertension.
Topics: Blood Pressure; Brain; Bufanolides; Calmodulin-Binding Proteins; Cerebrospinal Fluid; Cytochrome P-450 Enzyme System; Endosomal Sorting Complexes Required for Transport; Enzyme Inhibitors; Epithelial Sodium Channels; Humans; Hypertension; Immediate-Early Proteins; Nedd4 Ubiquitin Protein Ligases; Ouabain; Protein Serine-Threonine Kinases; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Mineralocorticoid; Receptors, Vasopressin; Renal Insufficiency; Renin-Angiotensin System; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary; Transcription, Genetic; Ubiquitin-Protein Ligases; Vasoconstrictor Agents | 2006 |
[Salt-sensitive hypertension and Na+/Ca2+ exchange: old and new mechanisms for linking high salt intake to vascular tone].
Topics: Animals; Animals, Genetically Modified; Hypertension; Mice; Ouabain; Rats; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary | 2006 |
Role of dietary salt in hypertension.
Topics: Animals; Blood Pressure; Diet, Sodium-Restricted; Disease Models, Animal; Enzyme Inhibitors; Humans; Hypertension; Ouabain; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase | 2006 |
[Endogenous digitalis-like factor].
Topics: Animals; Bufanolides; Cardenolides; Epithelial Sodium Channels; Humans; Hypertension; Kidney Tubules; Natriuretic Agents; Ouabain; Saponins; Sodium; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Vascular Resistance | 2006 |
Adducin polymorphisms and the treatment of hypertension.
Topics: Animals; Calmodulin-Binding Proteins; Diuretics; Humans; Hypertension; Multigene Family; Ouabain; Polymorphism, Genetic | 2007 |
Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth.
Topics: Animals; Antihypertensive Agents; Antineoplastic Agents; Blood Pressure; Bufanolides; Calcium; Cardiac Glycosides; Cardiovascular System; Cell Death; Cell Proliferation; Diabetes Mellitus; Digoxin; Humans; Hypertension; Molecular Structure; Myocardial Contraction; Myocytes, Cardiac; Neoplasms; Ouabain; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship | 2007 |
Ouabain-dependent signaling in caveolae as a novel therapeutic target for hypertension.
Topics: Androstanols; Animals; Antihypertensive Agents; Calmodulin-Binding Proteins; Caveolae; Humans; Hypertension; Ouabain; Rats; Signal Transduction | 2006 |
Role of long-term potentiation of sympathetic ganglia (gLTP) in hypertension.
Topics: Aging; Animals; Blood Pressure; Disease Models, Animal; Electric Stimulation; Ganglia, Sympathetic; Humans; Hypertension; Long-Term Potentiation; Obesity; Ouabain; Rats; Rats, Inbred SHR; Rats, Zucker; Receptors, Serotonin; Stress, Psychological | 2007 |
Magnesium ions and contraction of vascular smooth muscles: relationship to some vascular diseases.
Topics: Animals; Calcium; Diabetes Mellitus; Humans; Hypertension; Isoproterenol; Magnesium; Magnesium Deficiency; Muscle Contraction; Muscle, Smooth, Vascular; Neurotransmitter Agents; Ouabain; Potassium; Prostaglandins; Vascular Diseases; Vascular Resistance; Vasomotor System | 1981 |
The vascular Na+-K+ pump in low renin hypertension.
Topics: Adenosine Triphosphatases; Animals; Ca(2+) Mg(2+)-ATPase; Dogs; Humans; Hypertension; Ion Channels; Kidney; Kinetics; Male; Muscle, Smooth, Vascular; Myocardium; Ouabain; Peptides; Potassium; Rats; Renin; Sodium; Sodium-Potassium-Exchanging ATPase | 1984 |
The polymorphism of red cell Na and K transport in essential hypertension: findings, controversies, and perspectives.
Topics: Biological Transport; Erythrocytes; Humans; Hypertension; Kinetics; Lithium; Ouabain; Potassium; Sodium | 1984 |
[Pathology of cerebral edema. II. Experimental models and modifying agents].
Topics: Animals; Brain Edema; Brain Injuries; Brain Ischemia; Brain Neoplasms; Cats; Disease Models, Animal; Freezing; Hypertension; Hypotonic Solutions; Ouabain; Radiation Injuries, Experimental; Rats; Triethyltin Compounds | 1981 |
Disorders of body fluid balance: a new look into the mechanisms of disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Body Fluids; Capillary Permeability; Cardiotonic Agents; Diabetes Mellitus, Experimental; Diuretics; Dogs; Extravasation of Diagnostic and Therapeutic Materials; Female; Humans; Hypertension; Ischemia; Kidney; Kidney Failure, Chronic; Male; Microcirculation; Ouabain; Rats; Renal Circulation; Water-Electrolyte Imbalance | 1995 |
Endogenous ouabain, sodium balance and blood pressure.
Topics: Adrenal Cortex; Animals; Blood Pressure; Cardiotonic Agents; Humans; Hypertension; Ouabain; Sodium; Water-Electrolyte Balance | 1996 |
Endogenous ouabain, sodium balance and blood pressure: a review and a hypothesis.
Topics: Adrenal Gland Neoplasms; Animals; Blood Pressure; Brain; Cardiotonic Agents; Humans; Hypertension; Ouabain; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Water-Electrolyte Balance | 1996 |
Endogenous ouabain: role in the pathogenesis of hypertension.
Topics: Animals; Hypertension; Ouabain | 1996 |
Endogenous inhibitors of the Na,K pump.
Topics: Animals; Ascorbic Acid; Enzyme Inhibitors; Humans; Hypertension; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase | 1996 |
Franz Volhard Lecture 1996. Sodium transport inhibitors and hypertension.
Topics: Animals; Enzyme Inhibitors; Humans; Hypertension; Hypothalamus; Natriuresis; Ouabain; Peptides; Plants; Sodium-Potassium-Exchanging ATPase | 1996 |
Evidence-based medicine.
Topics: Animals; Blood Pressure; Cardiomegaly; Evidence-Based Medicine; Humans; Hypertension; Kidney; Nitric Oxide; Ouabain; Sodium-Potassium-Exchanging ATPase | 1998 |
Brain "ouabain", a neurosteroid, mediates sympathetic hyperactivity in salt-sensitive hypertension.
Topics: Animals; Brain; Cardiovascular System; Enzyme Inhibitors; Humans; Hypertension; Ouabain; Rats; Rats, Inbred SHR; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary; Steroids; Sympathetic Nervous System | 1998 |
An approach to the development of novel antihypertensive drugs: potential role of sodium pump inhibitors.
Topics: Animals; Antihypertensive Agents; Drug Design; Enzyme Inhibitors; Humans; Hypertension; Ouabain; Rats; Sodium; Sodium-Potassium-Exchanging ATPase | 1998 |
Vascular sodium pump: endothelial modulation and alterations in some pathological processes and aging.
Topics: Aging; Animals; Blood Vessels; Cardenolides; Diabetes Mellitus; Digoxin; Endothelium, Vascular; Humans; Hypertension; Nitric Oxide; Norepinephrine; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase; Vasodilation | 1999 |
Experimental studies on myocardial stretch and ventricular arrhythmia in hypertrophied and non-hypertrophied hearts.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Death, Sudden, Cardiac; Dogs; Electrocardiography; Gadolinium; Heart; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Isoproterenol; Meta-Analysis as Topic; Models, Cardiovascular; Myocardial Contraction; Myocardium; Nifedipine; Ouabain; Quinolines; Randomized Controlled Trials as Topic; Rats; Rats, Inbred SHR; Rats, Wistar; Ryanodine; Thiadiazines; Vasodilator Agents | 2000 |
Putative roles of ouabainlike compound in hypertension: revisited.
Topics: Animals; Cardenolides; Digoxin; Humans; Hypertension; Ouabain; Saponins | 2000 |
Ouabain, a new steroid hormone of adrenal gland and hypothalamus.
Topics: Adrenal Cortex; Adrenal Glands; Animals; Blood Pressure; Cattle; Hormones; Humans; Hypertension; Hypothalamus; Ouabain; Rats; White People | 2000 |
Endogenous cardiotonic steroids.
Topics: Androstanols; Animals; Antihypertensive Agents; Bufanolides; Cardenolides; Cardiac Glycosides; Cardiotonic Agents; Enzyme Inhibitors; Heart; Humans; Hypertension; Molecular Structure; Ouabain; Sodium-Potassium-Exchanging ATPase | 2001 |
Abnormalities of sodium pump function in hypertension and the role of endogenous cardiotonic steroids.
Topics: Absorption; Animals; Blood Pressure; Bufanolides; Cardiac Glycosides; Energy Metabolism; Humans; Hypertension; Kidney; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase | 2001 |
The hypothalamus and hypertension.
Topics: Acetylcholine; Angiotensins; Animals; Blood Pressure; Brain; Catecholamines; Enzyme Inhibitors; gamma-Aminobutyric Acid; Hemostatics; Histamine; Humans; Hypertension; Hypothalamus; Kidney; Neurons; Nitric Oxide; Ouabain; Peptides; Serotonin; Thyrotropin-Releasing Hormone; Vasopressins | 2001 |
[Incompatibility and interference of the major cardiologic drugs. Their undesirable effects].
Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Bradycardia; Cardiac Glycosides; Digitalis Glycosides; Disopyramide; Drug Interactions; Drug Synergism; Humans; Hypertension; Hypokalemia; Isoproterenol; Lidocaine; Monoamine Oxidase Inhibitors; Ouabain; Phenytoin; Prenylamine; Procainamide; Quinidine | 1976 |
Ouabain, digitalis-like factors and hypertension.
Topics: Animals; Blood Pressure; Blood Proteins; Cardenolides; Digitalis Glycosides; Digoxin; Humans; Hypertension; Ion Transport; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase | 1992 |
Ouabain--a link in the genesis of high blood pressure?
Topics: Cardiac Glycosides; Hypertension; Kidney; Muscle, Smooth; Natriuretic Agents; Ouabain | 1992 |
Endogenous ouabain: implications for cardiovascular disease diagnosis and therapy.
Topics: Blood Pressure; Blood Volume; Heart Failure; Humans; Hypertension; Ouabain; Water-Electrolyte Balance | 1992 |
Digoxin-like immunoreactivity: is it still worth measuring?
Topics: Animals; Blood Proteins; Cardenolides; Cross Reactions; Digoxin; Humans; Hypertension; Kidney Diseases; Ouabain; Radioimmunoassay; Saponins; Sodium-Potassium-Exchanging ATPase | 1991 |
Na+ and K+ transport alterations in hypertension.
Topics: Animals; Biological Transport; Erythrocytes; Humans; Hypertension; Ouabain; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase | 1991 |
Ion transport across plasma membrane in primary hypertension.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport, Active; Calcium; Cell Membrane; Cesium; Diffusion; Electrochemistry; Humans; Hypertension; Ion Channels; Kinetics; Magnesium; Mathematics; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rubidium; Sodium; Sodium-Potassium-Exchanging ATPase; Tissue Distribution | 1985 |
Changes in sodium pump activity and vascular contraction.
Topics: Animals; Calcium; Cell Membrane Permeability; Humans; Hypertension; In Vitro Techniques; Ion Channels; Muscle, Smooth, Vascular; Neurons; Neurotransmitter Agents; Ouabain; Potassium; Sodium; Vascular Resistance; Vasoconstriction | 1985 |
Pharmacologic agents for the in vivo detection of vascular sodium transport defects in hypertension.
Topics: Amiloride; Animals; Biological Transport, Active; Canrenone; Humans; Hypertension; Ion Channels; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase; Vascular Diseases | 1987 |
Pathophysiological role of cation transport and natriuretic factors in hypertension.
Topics: Animals; Calcium; Dogs; Humans; Hypertension; Muscle, Smooth, Vascular; Natriuretic Agents; Ouabain; Potassium; Rats; Rats, Inbred SHR; Sarcolemma; Sodium; Sodium-Potassium-Exchanging ATPase | 1987 |
Endogenous cardiac glycosidelike compounds.
Topics: Animals; Binding Sites; Blood Proteins; Blood Volume; Brain; Cardenolides; Digoxin; Humans; Hypertension; Lipids; Ouabain; Rats; Saponins; Sodium-Potassium-Exchanging ATPase; Steroids; Vertebrates | 1987 |
Characteristics of hypertensive patients with increased plasma Na+-K+ pump inhibitory activity.
Topics: Adult; Age Factors; ATPase Inhibitory Protein; Black People; Blood Proteins; Female; Glucosephosphate Dehydrogenase; Humans; Hypertension; Kidney Function Tests; Leukocytes; Male; Middle Aged; Ouabain; Proteins; Renin; Rubidium; Sex Factors; Sodium-Potassium-Exchanging ATPase | 1985 |
Cellular sodium transport in essential hypertension.
Topics: Animals; Biological Transport; Disease Models, Animal; Drug Resistance; Erythrocytes; Humans; Hypertension; Leukocytes; Lithium; Models, Biological; Natriuretic Agents; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase | 1986 |
Membrane transport of ions in hypertension: a review.
Topics: Animals; Biological Transport, Active; Blood Pressure; Cell Membrane; Cell Membrane Permeability; Humans; Hypertension; Membrane Fluidity; Models, Biological; Norepinephrine; Ouabain; Potassium; Rats; Rats, Inbred SHR; Sodium; Sodium-Potassium-Exchanging ATPase; Stress, Physiological | 1986 |
Evidence for a circulating Na,K-pump inhibitor in essential hypertension.
Topics: Animals; Blood Pressure; Dogs; Erythrocytes; Humans; Hypertension; Kidney; Leukocytes; Muscle, Smooth, Vascular; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase | 1986 |
Regulation of the concentration of 3H-ouabain binding sites in mammalian skeletal muscle--effects of age, K-depletion, thyroid status and hypertension.
Topics: Age Factors; Animals; Binding Sites; Digitalis Glycosides; Female; Guinea Pigs; Homeostasis; Humans; Hypertension; Hypokalemia; In Vitro Techniques; Male; Mice; Muscles; Myocardium; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sodium; Thyroid Diseases; Tritium | 1987 |
Evidence for a circulating sodium-potassium pump inhibitor in low renin hypertension.
Topics: Animals; Arteries; ATPase Inhibitory Protein; Blood Proteins; Blood Volume; Humans; Hypertension; Ouabain; Proteins; Renin; Rubidium | 1985 |
Ionic composition of the arterial wall.
Topics: Animals; Aorta; Arteries; Calcium; Carotid Arteries; Chlorine; Dinitrophenols; Dogs; Electric Stimulation; Electrolytes; Extracellular Space; Femoral Artery; Humans; Hydrogen-Ion Concentration; Hypertension; Jejunum; Methods; Muscle, Smooth; Nitrobenzenes; Ouabain; Potassium; Potassium Isotopes; Rabbits; Rats; Sodium; Sodium Isotopes; Time Factors | 1969 |
9 trial(s) available for ouabain and Hypertension
| Article | Year |
|---|---|
Selective association of endogenous ouabain with subclinical organ damage in treated hypertensive patients.
Topics: Aged; Antihypertensive Agents; Biomarkers; Blood Pressure Monitoring, Ambulatory; Carotid Artery, Common; Catecholamines; Chronic Disease; Circadian Rhythm; Diabetes Mellitus, Type 2; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney Diseases; Male; Middle Aged; Natriuretic Peptide, Brain; Ouabain; Peptide Fragments; Risk Factors | 2011 |
Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies.
Topics: Androstanols; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Female; Genetic Loci; Humans; Hydrochlorothiazide; Hypertension; Intramolecular Transferases; Kidney; Losartan; Male; Middle Aged; Mutant Proteins; Ouabain; Placebos; Polymorphism, Single Nucleotide; Systole; Time Factors; Transfection | 2010 |
Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin.
Topics: Adult; Aldosterone; Androstanols; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Cross-Over Studies; Double-Blind Method; Europe; Female; Humans; Hypertension; Male; Middle Aged; Mutation; Ouabain; Renin; Sodium; Sodium-Potassium-Exchanging ATPase; Time Factors; Treatment Outcome | 2011 |
OASIS-HT: design of a pharmacogenomic dose-finding study.
Topics: Administration, Oral; Adult; Androstanols; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Molecular Conformation; Ouabain; Risk Factors; Time Factors; Treatment Outcome | 2005 |
Endogenous sodium pump inhibitors and age-associated increases in salt sensitivity of blood pressure in normotensives.
Topics: Adult; Age Factors; Aged; Aging; Blood Pressure; Body Mass Index; Bufanolides; Enzyme Inhibitors; Female; Humans; Hypertension; Linear Models; Middle Aged; Models, Biological; Natriuresis; Ouabain; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; Systole; Time Factors; Up-Regulation | 2008 |
Effects of canrenoate on red cell sodium transport and calf flow in essential hypertension.
Topics: Adult; Biological Transport; Blood Pressure; Canrenoic Acid; Captopril; Erythrocytes; Female; Humans; Hypertension; Infusions, Intravenous; Leg; Male; Middle Aged; Ouabain; Regional Blood Flow; Renin; Sodium; Vascular Resistance | 1993 |
Sodium pump numbers and cation transport of lymphocytes in pregnancy-induced hypertension.
Topics: Adult; Biological Transport, Active; Female; Humans; Hypertension; Lymphocytes; Ouabain; Pregnancy; Pregnancy Complications, Cardiovascular; Rubidium Radioisotopes; Sodium; Sodium-Potassium-Exchanging ATPase | 1990 |
Ketanserin and red blood cell sodium content in hypertension.
Topics: Adult; Aged; Erythrocyte Deformability; Erythrocytes; Humans; Hypertension; Ketanserin; Middle Aged; Myocardial Infarction; Ouabain; Piperidines; Serotonin; Serotonin Antagonists; Sodium | 1985 |
Sympathetic vasoconstriction as a mechanism of action of ouabain in forearm arterioles of hypertensive patients.
Topics: Arterioles; Female; Forearm; Humans; Hypertension; Male; Ouabain; Regional Blood Flow; Sympathomimetics; Vasoconstrictor Agents; Vasomotor System | 1989 |
437 other study(ies) available for ouabain and Hypertension
| Article | Year |
|---|---|
Sleep deprivation is associated with increased circulating levels of endogenous ouabain: Potential role in bipolar disorder.
Topics: Animals; Bipolar Disorder; Humans; Hypertension; Mice; Ouabain; Sleep Deprivation; Sodium-Potassium-Exchanging ATPase | 2022 |
Effects of renal denervation on endogenous ouabain in spontaneously hypertensive rats.
Topics: Animals; Denervation; Hypertension; Kidney; Male; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Sodium; Sodium-Potassium-Exchanging ATPase | 2023 |
Small artery remodeling and stiffening in deoxycorticosterone acetate-salt hypertensive rats involves the interaction between endogenous ouabain/Na + K + -ATPase/cSrc signaling.
Topics: Acetates; Adenosine Triphosphatases; Animals; Blood Pressure; Desoxycorticosterone; Desoxycorticosterone Acetate; ErbB Receptors; Hypertension; Mesenteric Arteries; Ouabain; Rats | 2023 |
Ouabain regulates kidney metabolic profiling in rat offspring of intrauterine growth restriction induced by low-protein diet.
Topics: Animals; Arginine; Diet, Protein-Restricted; Female; Fetal Development; Fetal Growth Retardation; Fetal Weight; Hypertension; Kidney; Kidney Diseases; Kidney Glomerulus; Male; Metabolomics; Ouabain; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2020 |
Role of GSPE in improving early cerebral vascular damage by inhibition of Profilin-1 expression in a ouabain-induced hypertension model.
Topics: Animals; Blood Pressure; Grape Seed Extract; Hypertension; Male; Nitric Oxide Synthase Type III; Ouabain; Proanthocyanidins; Profilins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Remodeling | 2018 |
Comment on: Endogenous Ouabain and Related Genes in the Translation from Hypertension to Renal Diseases, Int. J. Mol. Sci. 2018, 19, 1948.
Topics: Humans; Hypertension; Kidney Diseases; Ouabain | 2019 |
Reply: "Comment on: Endogenous Ouabain and Related Genes in the Translation from Hypertension to Renal Diseases".
Topics: Animals; Genes; Humans; Hypertension; Kidney Diseases; Ouabain; Rats | 2019 |
Increased constrictor tone induced by ouabain treatment in rats.
Topics: Animals; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Female; Heart; Hypertension; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Myometrium; Ouabain; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2013 |
Angiotensin II-induced hypertension increases plasma membrane Na pump activity by enhancing Na entry in rat thick ascending limbs.
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension; Loop of Henle; Male; Ouabain; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Potassium-Exchanging ATPase | 2013 |
Rostafuroxin ameliorates endothelial dysfunction and oxidative stress in resistance arteries from deoxycorticosterone acetate-salt hypertensive rats: the role of Na+K+-ATPase/ cSRC pathway.
Topics: Androstanols; Animals; Antihypertensive Agents; Blood Pressure; Cyclooxygenase 2; Desoxycorticosterone Acetate; Endothelium, Vascular; Humans; Hypertension; Male; Mesenteric Arteries; NADPH Oxidases; Ouabain; Oxidative Stress; Rats; Rats, Wistar; Signal Transduction; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; src-Family Kinases; Vascular Resistance; Vasodilation | 2014 |
Molecular mechanism of Na(+),K(+)-ATPase malfunction in mutations characteristic of adrenal hypertension.
Topics: Adrenal Gland Diseases; Binding Sites; Cations, Monovalent; Humans; Hypertension; Molecular Dynamics Simulation; Mutation; Ouabain; Protein Binding; Sodium; Sodium-Potassium-Exchanging ATPase; Static Electricity; Water | 2014 |
ANG-(3-4) inhibits renal Na+-ATPase in hypertensive rats through a mechanism that involves dissociation of ANG II receptors, heterodimers, and PKA.
Topics: Adenosine Triphosphatases; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Cation Transport Proteins; Cyclic AMP-Dependent Protein Kinases; Dipeptides; Hypertension; Imidazoles; Kidney Tubules, Proximal; Ouabain; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Sodium; Sodium-Potassium-Exchanging ATPase | 2014 |
Effect of ouabain on the pathogenesis of hypertension in rats.
Topics: Animals; Blood Pressure; Digoxin; Hypertension; In Situ Hybridization; Male; Ouabain; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 2014 |
Proliferating cell nuclear antigen involved in the repair process of ouabain-induced brain damage independent of hypertension in rats.
Topics: Animals; Blood Pressure; Hypertension; Immunohistochemistry; Male; Ouabain; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Sodium-Potassium-Exchanging ATPase | 2014 |
Rostafuroxin protects from podocyte injury and proteinuria induced by adducin genetic variants and ouabain.
Topics: Androstanols; Animals; Antihypertensive Agents; Calmodulin-Binding Proteins; Disease Models, Animal; Female; Genetic Variation; Hypertension; Kidney; Male; Mice; Mice, Knockout; Ouabain; Podocytes; Proteinuria; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 2014 |
Wistar rats resistant to the hypertensive effects of ouabain exhibit enhanced cardiac vagal activity and elevated plasma levels of calcitonin gene-related peptide.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Cardiotonic Agents; Hypertension; Male; Ouabain; Rats; Rats, Wistar; Vagus Nerve | 2014 |
Enhanced Na⁺, K⁺-ATPase activity and endothelial modulation decrease phenylephrine-induced contraction in aorta from ouabain-treated normotensive and hypertensive rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cyclooxygenase 2; Endothelium, Vascular; Hypertension; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Ouabain; Phenylephrine; Rats, Inbred SHR; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Species Specificity; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2014 |
Chronic ouabain treatment induces Rho kinase activation.
Topics: Amides; Animals; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Male; Myosin-Light-Chain Phosphatase; Ouabain; Phenylephrine; Potassium Chloride; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases | 2015 |
Lanosterol Synthase Gene Polymorphisms and Changes in Endogenous Ouabain in the Response to Low Sodium Intake.
Topics: Adolescent; Adult; Aged; Blood Pressure; Diet, Sodium-Restricted; Enzyme Inhibitors; Female; Genotype; Humans; Hypertension; Intramolecular Transferases; Male; Middle Aged; Ouabain; Polymorphism, Genetic; RNA; Young Adult | 2016 |
Endogenous ouabain and aldosterone are coelevated in the circulation of patients with essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Essential Hypertension; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Natriuresis; Ouabain; Renin; Sodium Chloride, Dietary | 2016 |
Low dose ouabain stimulates NaK ATPase α1 subunit association with angiotensin II type 1 receptor in renal proximal tubule cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Hypertension; Kidney Tubules, Proximal; Mice; Ouabain; Peptidyl-Dipeptidase A; Phosphorylation; Protein Binding; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Transfection | 2016 |
ASSOSIATION OF ENDOGENOUS CARDIOTONIC STEROIDS WITH SALT-SENSITIVITY OF BLOOD PRESSURE IN GEORGIAN POPULATION.
Topics: Blood Pressure; Bufanolides; Cardiac Glycosides; Case-Control Studies; Female; Georgia (Republic); Humans; Hypertension; Male; Ouabain; Sex Factors; Sodium Chloride, Dietary | 2016 |
Ouabain treatment increases nitric oxide bioavailability and decreases superoxide anion production in cerebral vessels.
Topics: Animals; Cerebral Arteries; Enzyme Inhibitors; Hypertension; Male; Nitric Oxide; Ouabain; Rats; Rats, Wistar; Superoxides; Vasoconstriction; Vasodilation | 2008 |
Ouabain treatment changes the role of endothelial factors in rat resistance arteries.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Cardiotonic Agents; Cyclooxygenase 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Heart Rate; Hypertension; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Ouabain; Phenylephrine; Rats; Rats, Wistar | 2008 |
Mechanisms in the PVN mediating local and central sodium-induced hypertension in Wistar rats.
Topics: Aldosterone; Amiloride; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Cerebrospinal Fluid; Diuretics; Dose-Response Relationship, Drug; Eplerenone; Heart Rate; Hypertension; Injections, Intraventricular; Losartan; Ouabain; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Sodium; Spironolactone | 2009 |
Activation of BKCa channels by nitric oxide prevents coronary artery endothelial dysfunction in ouabain-induced hypertensive rats.
Topics: Animals; Coronary Vessels; Endothelium, Vascular; Hydrazines; Hypertension; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Male; Nitric Oxide; Ouabain; Potassium Channels; Pyrazoles; Pyridines; Rats; Rats, Wistar; Vasodilation | 2009 |
Steroid biosynthesis and renal excretion in human essential hypertension: association with blood pressure and endogenous ouabain.
Topics: 3-Hydroxysteroid Dehydrogenases; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Pressure; Cholesterol Side-Chain Cleavage Enzyme; Cohort Studies; Female; Haplotypes; Humans; Hypertension; Male; Middle Aged; Ouabain; Polymorphism, Single Nucleotide; Potassium; Sodium | 2009 |
Enhanced pressor response to increased CSF sodium concentration and to central ANG I in heterozygous alpha2 Na+ -K+ -ATPase knockout mice.
Topics: Angiotensin I; Animals; Blood Pressure; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Heart Rate; Hypertension; Hypothalamus; Injections, Intraventricular; Male; Mice; Mice, Knockout; Ouabain; Renin-Angiotensin System; Sodium; Sodium-Potassium-Exchanging ATPase | 2009 |
Chronic ouabain treatment exacerbates blood pressure elevation in spontaneously hypertensive rats: the role of vascular mechanisms.
Topics: Acetylcholine; Animals; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Endothelium, Vascular; Hypertension; In Vitro Techniques; Indomethacin; Male; Ouabain; Pentanoic Acids; Phenylephrine; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thromboxane-A Synthase; Vasoconstriction; Vasodilation | 2009 |
Na(+)-ATPase in spontaneous hypertensive rats: possible AT(1) receptor target in the development of hypertension.
Topics: Angiotensin II; Animals; Enzyme Activation; Hypertension; Kidney Tubules, Proximal; Kinetics; Losartan; Male; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Sodium-Potassium-Exchanging ATPase | 2010 |
Low-dose ouabain constricts small arteries from ouabain-hypertensive rats: implications for sustained elevation of vascular resistance.
Topics: Acetylcholine; Animals; Blood Pressure; Caffeine; Calcium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Male; Mesenteric Arteries; Ouabain; Phenylephrine; Phosphodiesterase Inhibitors; Potassium; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2009 |
Sodium transport in the choroid plexus and salt-sensitive hypertension.
Topics: Amiloride; Animals; Biological Transport; Choroid Plexus; Disease Models, Animal; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Hypertension; Male; Ouabain; Rats; Rats, Inbred Dahl; Rats, Wistar; RNA, Messenger; Sodium; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary | 2009 |
[Protective effects of ouabain conjugated peptide from Ph.D.-7 Library on vascular endothelial cell].
Topics: Amino Acid Sequence; Base Sequence; Cell Death; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation, Enzymologic; Hypertension; Oligopeptides; Ouabain; Peptide Library; RNA, Messenger; Sequence Analysis, DNA; Sodium; Sodium-Potassium-Exchanging ATPase; Time Factors; Up-Regulation | 2009 |
A key role for Na+/K+-ATPase in the endothelium-dependent oscillatory activity of mouse small mesenteric arteries.
Topics: Animals; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Ouabain; Sodium-Potassium-Exchanging ATPase; Vascular Resistance | 2009 |
Upregulation of Na+ and Ca2+ transporters in arterial smooth muscle from ouabain-induced hypertensive rats.
Topics: Animals; Blotting, Western; Calcium Channels; Cardiotonic Agents; Fluorescent Dyes; Fura-2; Homeostasis; Hypertension; Image Processing, Computer-Assisted; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; TRPC Cation Channels; TRPC6 Cation Channel; Up-Regulation | 2010 |
Dopamine-mediated inhibition of renal Na+/K+-ATPase in HK-2 cells is reduced by ouabain.
Topics: Blotting, Western; Cardiotonic Agents; Cell Culture Techniques; Cell Line; Cyclic AMP; Dopamine; Dopamine Agonists; Fenoldopam; Humans; Hypertension; Immunoprecipitation; Ion Transport; Kidney Tubules, Proximal; Ouabain; Phosphorylation; Receptors, Dopamine D1; RNA, Messenger; Sodium; Sodium-Potassium-Exchanging ATPase | 2010 |
A low concentration of ouabain (0.18 microg/kg) enhances hypertension in spontaneously hypertensive rats by inhibiting the Na+ pump and activating the renin-angiotensin system.
Topics: Animals; Antihypertensive Agents; Enzyme Inhibitors; Hypertension; Male; Ouabain; Phenylephrine; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium-Potassium-Exchanging ATPase | 2010 |
Endogenous ouabain and the renin-angiotensin-aldosterone system: distinct effects on Na handling and blood pressure in human hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Kidney Tubules; Linear Models; Male; Middle Aged; Natriuresis; Ouabain; Renin; Renin-Angiotensin System; Sodium | 2011 |
[Role of renal sympathetic nerves in renal sodium transport in ouabain-hypertensive rats].
Topics: Animals; Hypertension; Kidney; Male; Ouabain; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channels; Sympathetic Nervous System | 2010 |
Long-term ouabain treatment impairs vascular function in resistance arteries.
Topics: Animals; Cyclooxygenase 2; Endothelium, Vascular; Hypertension; Male; Mesenteric Arteries; Nitric Oxide; Ouabain; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Systole; Vascular Resistance; Vasoconstriction | 2011 |
Age-dependent effect of ouabain on renal Na+,K+-ATPase.
Topics: Age Factors; Animals; Blood Pressure; Cardiotonic Agents; Hypertension; Kidney Tubules, Proximal; Male; Ouabain; Rats; Rats, Inbred WKY; Sodium; Sodium-Potassium-Exchanging ATPase | 2011 |
Effects of mono- and dual blockade of the renin-angiotensin system on markers of cardiovascular status in hypertensive patients with mild and moderate renal failure.
Topics: Aged; Albumins; Arteries; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cardiovascular Physiological Phenomena; Catecholamines; Cross-Sectional Studies; Diabetic Nephropathies; Female; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Nephrosclerosis; Ouabain; Peptide Fragments; Renal Insufficiency; Renin-Angiotensin System; Retrospective Studies | 2011 |
Hypertension from chronic central sodium chloride in mice is mediated by the ouabain-binding site on the Na,K-ATPase α₂-isoform.
Topics: Animals; Binding Sites; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brain; Cardenolides; Disease Models, Animal; Heart Rate; Hypertension; Infusions, Intraventricular; Mice; Mice, Knockout; Mice, Transgenic; Mutation; Ouabain; Saponins; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Telemetry; Time Factors | 2011 |
DOCA-salt hypertension does not require the ouabain-sensitive binding site of the α2 Na,K-ATPase.
Topics: Animals; Binding Sites; Blood Pressure; Bufanolides; Desoxycorticosterone; Digoxin; Hypertension; Immunoglobulin Fab Fragments; Mice; Myocardial Contraction; Ouabain; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 2012 |
Ouabain and insulin induce sodium pump endocytosis in renal epithelium.
Topics: Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Endocytosis; Enzyme Inhibitors; Hypertension; Hypoglycemic Agents; Immunoprecipitation; Insulin; Kidney Tubules, Proximal; Male; Mice; Mice, Knockout; Ouabain; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Swine; Urothelium | 2012 |
Expression of heme oxygenase-1 in thick ascending loop of henle attenuates angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Furosemide; Heme Oxygenase-1; Hypertension; Loop of Henle; Mice; Mice, Transgenic; Ouabain; Rubidium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Uromodulin | 2012 |
Nanomolar ouabain increases NCX1 expression and enhances Ca2+ signaling in human arterial myocytes: a mechanism that links salt to increased vascular resistance?
Topics: Adolescent; Adult; Aged; Animals; Blood Pressure; Blotting, Western; Calcium Signaling; Cardenolides; Cell Membrane; Cell Shape; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Female; Homeostasis; Humans; Hypertension; Immunohistochemistry; Inositol 1,4,5-Trisphosphate Receptors; Male; Mammary Arteries; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Ouabain; Rats; Saponins; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium Chloride; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Time Factors; TRPC Cation Channels; Up-Regulation; Vascular Resistance; Young Adult | 2012 |
Grape seed proanthocyanidin extracts enhance endothelial nitric oxide synthase expression through 5'-AMP activated protein kinase/Surtuin 1-Krüpple like factor 2 pathway and modulate blood pressure in ouabain induced hypertensive rats.
Topics: AMP-Activated Protein Kinases; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Grape Seed Extract; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Kruppel-Like Transcription Factors; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Ouabain; Phytotherapy; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Seeds; Sirtuin 1; Vitis | 2012 |
[Effect of the Na+, K(+)-ATPase modulation in neurons of the medulla oblongata on hemodynamic effects in spontaneously hypertensive rats].
Topics: Animals; Blood Pressure; Cardiotonic Agents; Enzyme Activation; Hemodynamics; Hypertension; Injections, Intraventricular; Microinjections; Neurons; Olivary Nucleus; Ouabain; Potassium Magnesium Aspartate; Rats; Rats, Inbred SHR; Reticular Formation; Sodium-Potassium-Exchanging ATPase; Solitary Nucleus | 2012 |
Alteration in ouabain-sensitive sodium potassium pump of erythrocytes during pregnancy induced hypertension: a kinetic study.
Topics: Enzyme Inhibitors; Erythrocytes; Female; Humans; Hypertension; Kinetics; Ouabain; Pregnancy; Sodium-Potassium-Exchanging ATPase | 2002 |
Ouabain-induced hypertension is accompanied by increases in endothelial vasodilator factors.
Topics: Animals; Biological Factors; Blood Pressure; Cardiotonic Agents; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Guanidines; Hypertension; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ouabain; Phenylephrine; Potassium Channel Blockers; Rats; Rats, Wistar; Tetraethylammonium; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2002 |
Ouabain changes arterial blood pressure and vascular reactivity to phenylephrine in L-NAME-induced hypertension.
Topics: Animals; Blood Pressure; Drug Synergism; Hypertension; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Ouabain; Phenylephrine; Potassium Channels; Rats; Rats, Wistar | 2003 |
Ouabain as a mammalian hormone.
Topics: Adult; Animals; Blood Pressure; Cardiac Glycosides; Cardiotonic Agents; Cattle; Cholesterol; Dogs; Exercise; Exercise Test; Hormones; Humans; Hypertension; Immunoglobulin mu-Chains; Middle Aged; Ouabain; Physical Conditioning, Animal; Reference Values; Steroids | 2003 |
Membrane ion transport in erythrocytes of salt hypertensive Dahl rats and their F2 hybrids: the importance of cholesterol.
Topics: Animals; Biological Transport; Blood Pressure; Bumetanide; Cholesterol; Diuretics; Enzyme Inhibitors; Erythrocyte Membrane; Hypertension; Male; Ouabain; Rats; Rats, Inbred Dahl; Rubidium; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; Triglycerides | 2003 |
Characterization of the neutralizing activity of digoxin-specific Fab toward ouabain-like steroids.
Topics: Animals; Digoxin; Enzyme-Linked Immunosorbent Assay; Humans; Hypertension; Immunoglobulin Fab Fragments; Ouabain; Rats; Sodium-Potassium-Exchanging ATPase; Steroids; Tritium | 2004 |
Coordinated shifts in Na/K-ATPase isoforms and their endogenous ligands during cardiac hypertrophy and failure in NaCl-sensitive hypertension.
Topics: Animals; Bufanolides; Cardiac Output, Low; Cardiomegaly; Enzyme Inhibitors; Hypertension; Isoenzymes; Ligands; Male; Ouabain; Rats; Rats, Inbred Dahl; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 2004 |
Neurogenic nitric oxide release increases in mesenteric arteries from ouabain hypertensive rats.
Topics: Animals; Electric Stimulation; Enzyme Inhibitors; Hypertension; Indazoles; Male; Mesenteric Arteries; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Ouabain; Rats; Rats, Wistar; Tritium; Vasoconstriction | 2004 |
Increases in CSF [Na+] precede the increases in blood pressure in Dahl S rats and SHR on a high-salt diet.
Topics: Animals; Aorta, Abdominal; Blood Pressure; Brain; Cardenolides; Cardiotonic Agents; Digoxin; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Immunoglobulin Fab Fragments; Injections, Intraventricular; Male; Osmolar Concentration; Ouabain; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Saponins; Sodium; Sodium Chloride, Dietary; Telemetry | 2004 |
Brain Na+,K+-ATPase isozyme activity and protein expression in ouabain-induced hypertension.
Topics: Animals; Blood Pressure; Cerebral Cortex; Down-Regulation; Enzyme Inhibitors; Hypertension; Hypothalamus; Immunoglobulin Fab Fragments; Injections, Intraventricular; Injections, Subcutaneous; Isoenzymes; Male; Medulla Oblongata; Microsomes; Ouabain; Pons; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 2004 |
Ouabain-induced hypertension alters the participation of endothelial factors in alpha-adrenergic responses differently in rat resistance and conductance mesenteric arteries.
Topics: Animals; Antihypertensive Agents; Blotting, Western; Cardiotonic Agents; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Losartan; Male; Mesenteric Arteries; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; Ouabain; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha; Vascular Resistance; Vasoconstrictor Agents | 2004 |
The alpha2-isoform of Na-K-ATPase mediates ouabain-induced hypertension in mice and increased vascular contractility in vitro.
Topics: Anesthesia; Animals; Aorta; Blood Pressure; Cardiotonic Agents; Endothelium, Vascular; Genotype; Hypertension; In Vitro Techniques; Isomerism; Mice; Ouabain; Portal Vein; Restraint, Physical; Sodium-Potassium-Exchanging ATPase; Vasoconstriction | 2005 |
Chronic central infusion of aldosterone leads to sympathetic hyperreactivity and hypertension in Dahl S but not Dahl R rats.
Topics: Aldosterone; Animals; Baroreflex; Blood Pressure; Cardiotonic Agents; Heart Rate; Hypertension; Injections, Intraventricular; Male; Ouabain; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Stress, Physiological; Sympathetic Nervous System | 2005 |
Salt-sensitive hypertension is triggered by Ca2+ entry via Na+/Ca2+ exchanger type-1 in vascular smooth muscle.
Topics: Alternative Splicing; Aniline Compounds; Animals; Blood Pressure; Calcium; Hypertension; Immunoblotting; Immunohistochemistry; Male; Mesenteric Arteries; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Ouabain; Phenyl Ethers; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Sodium-Calcium Exchanger; Vasoconstriction | 2004 |
Hypertension with a grain of salt.
Topics: Alternative Splicing; Aniline Compounds; Animals; Blood Pressure; Calcium; Hypertension; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Ouabain; Phenyl Ethers; Sodium Chloride, Dietary; Sodium-Calcium Exchanger | 2004 |
High circulating levels of endogenous ouabain in the offspring of hypertensive and normotensive individuals.
Topics: Adult; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Echocardiography, Doppler; Family Health; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Linear Models; Male; Ouabain | 2005 |
Endogenous ouabain: upregulation of steroidogenic genes in hypertensive hypothalamus but not adrenal.
Topics: Adrenal Glands; Animals; Cholesterol Side-Chain Cleavage Enzyme; Hypertension; Hypothalamus; Multienzyme Complexes; Oligonucleotide Array Sequence Analysis; Ouabain; PC12 Cells; Polymerase Chain Reaction; Progesterone Reductase; Rats; RNA Interference; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Steroid Isomerases | 2005 |
[Renal sodium handling in ouabain-hypertensive rats].
Topics: Animals; Hypertension; Kidney Tubules, Proximal; Lithium; Male; Natriuresis; Ouabain; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium | 2005 |
The highly conserved cardiac glycoside binding site of Na,K-ATPase plays a role in blood pressure regulation.
Topics: Adrenocorticotropic Hormone; Animals; Binding Sites; Blood Pressure; Cardiac Glycosides; Conserved Sequence; Drug Resistance; Genetic Engineering; Humans; Hypertension; Mice; Ouabain; Protein Isoforms; Sodium-Potassium-Exchanging ATPase | 2005 |
Cardiac glycoside downregulates NHE3 activity and expression in LLC-PK1 cells.
Topics: Animals; Cardiotonic Agents; Cell Culture Techniques; Down-Regulation; Epithelial Cells; Humans; Hypertension; Kidney Tubules, Proximal; Male; Ouabain; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Water-Electrolyte Balance | 2006 |
Ouabain at pathological concentrations might induce damage in human vascular endothelial cells.
Topics: Aorta; Cell Death; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Humans; Hypertension; Ouabain; Shal Potassium Channels; Umbilical Veins | 2006 |
Pleiotropic effects of hydrogen peroxide in arteries and veins from normotensive and hypertensive rats.
Topics: Animals; Aorta, Thoracic; Calcium; Desoxycorticosterone; Drug Synergism; Extracellular Fluid; Hydrogen Peroxide; Hypertension; Male; Ouabain; Oxidants; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Vasoconstriction; Vasodilation; Venae Cavae | 2006 |
Resibufogenin corrects hypertension in a rat model of human preeclampsia.
Topics: Animals; Blood Pressure; Bufanolides; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Hypertension; Isoenzymes; Molecular Structure; Ouabain; Pre-Eclampsia; Pregnancy; Rats; Sodium-Potassium-Exchanging ATPase | 2006 |
Molecular mechanisms linking sodium to hypertension: report of a symposium.
Topics: Animals; Humans; Hypertension; Ouabain; Protein Subunits; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Vasoconstriction | 2006 |
Alterations in structure and mechanics of resistance arteries from ouabain-induced hypertensive rats.
Topics: Adaptation, Physiological; Animals; Biomechanical Phenomena; Elasticity; Hypertension; Male; Mesenteric Arteries; Ouabain; Rats; Rats, Wistar; Vascular Resistance | 2006 |
Central and peripheral renin-angiotensin systems in ouabain-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Cardiotonic Agents; Central Nervous System; Heart; Heart Rate; Hypertension; Kidney; Male; Ouabain; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A; Peripheral Nervous System; Preoptic Area; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Subfornical Organ | 2006 |
Effect of sodium delivery on superoxide and nitric oxide in the medullary thick ascending limb.
Topics: Animals; Biological Availability; Biological Transport; Enzyme Inhibitors; Hydrogen Peroxide; Hypertension; Kidney Medulla; Loop of Henle; Male; Nitric Oxide; Ouabain; Oxidative Stress; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sodium; Sodium Chloride; Superoxides | 2006 |
Ouabain-induced hypertension enhances left ventricular contractility in rats.
Topics: Adaptation, Physiological; Animals; Blood Pressure; Calcium-Transporting ATPases; Cardiotonic Agents; Heart Ventricles; Hypertension; In Vitro Techniques; Male; Myocardial Contraction; Myosin Heavy Chains; Myosins; Ouabain; Papillary Muscles; Protein Isoforms; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Potassium-Exchanging ATPase; Ventricular Function; Ventricular Function, Left | 2006 |
[Contribution of endothelin and its receptors to ouabain-induced hypertension in rats].
Topics: Animals; Endothelins; Hypertension; Immunohistochemistry; Male; Myocardium; Ouabain; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
[Changes in renal sodium transport during hypertension development in ouabain-hypertensive rats].
Topics: Animals; Blood Pressure; Creatinine; Hypertension; Ion Transport; Kidney Tubules, Proximal; Male; Ouabain; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium | 2006 |
Targeting Ouabain- and Adducin-dependent mechanisms of hypertension and cardiovascular remodeling as a novel pharmacological approach.
Topics: Androstanols; Animals; Antihypertensive Agents; Calmodulin-Binding Proteins; Cardiovascular System; Humans; Hypertension; Models, Cardiovascular; Ouabain; Sodium-Potassium-Exchanging ATPase | 2007 |
Na+/K+-ATPase alpha isoforms expression in stroke-prone spontaneously hypertensive rat heart ventricles: effect of salt loading and lacidipine treatment.
Topics: Animals; Calcium Channel Blockers; Cardiomegaly; Dihydropyridines; Heart Ventricles; Hypertension; Isoenzymes; Male; Ouabain; Protein Subunits; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; Stroke | 2007 |
Regulation of renal ouabain-resistant Na+-ATPase by leptin, nitric oxide, reactive oxygen species, and cyclic nucleotides: implications for obesity-associated hypertension.
Topics: Adenosine Triphosphatases; Animals; Cation Transport Proteins; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Hypertension; Kidney Tubules, Proximal; Leptin; Male; Nitric Oxide; Nucleotides, Cyclic; Obesity; Ouabain; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 2007 |
Marinobufagenin in hypertensive patients with obstructive sleep apnea.
Topics: Adult; Blood Pressure Determination; Bufanolides; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Polysomnography; Sleep Apnea, Obstructive | 2006 |
Sodium pumps: ouabain, ion transport, and signaling in hypertension.
Topics: Calcium; Cardiotonic Agents; Carrier Proteins; Enzyme Inhibitors; Humans; Hypertension; Ouabain; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Steroids | 2007 |
Mechanisms of hypertension.
Topics: Cardenolides; Humans; Hypertension; Ouabain; Potassium; Saponins; Sodium; Sodium-Potassium-Exchanging ATPase | 2007 |
Mechanisms of hypertension.
Topics: Cardenolides; Humans; Hypertension; Ouabain; Saponins; Sodium; Sodium-Potassium-Exchanging ATPase | 2007 |
Relationships among endogenous ouabain, alpha-adducin polymorphisms and renal sodium handling in primary hypertension.
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calmodulin-Binding Proteins; Female; Genetic Predisposition to Disease; Humans; Hypertension; Kidney Tubules; Male; Middle Aged; Ouabain; Polymorphism, Single Nucleotide; Sodium | 2008 |
ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit.
Topics: Adrenergic beta-Agonists; Adrenocorticotropic Hormone; Aldosterone; Animals; Binding Sites; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cerebrovascular Circulation; Corticosterone; Disease Models, Animal; Drug Resistance; Enzyme Inhibitors; Genotype; Hypertension; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Mutation; Myocardium; Ouabain; Phenotype; Regional Blood Flow; Renal Circulation; Sodium-Potassium-Exchanging ATPase; Splanchnic Circulation; Telemetry; Time Factors; Vascular Resistance; Vasoconstrictor Agents; Ventricular Function, Left | 2008 |
Na+,K+-ATPase activity and responsiveness of vascular smooth muscle to norepinephrine, angiotensin II and calcium ionophore A23187 in guinea pig aortic strips.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Calcimycin; Calcium; Guinea Pigs; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Sodium-Potassium-Exchanging ATPase; Vasoconstriction | 1984 |
Reduced number of erythrocyte sodium pump units in essential hypertension.
Topics: Adult; Binding Sites; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase | 1984 |
An endogenous ouabain-like factor associated with hypertensive pregnant women.
Topics: Adolescent; Adult; Amniotic Fluid; Blood Pressure; Digoxin; Female; Humans; Hypertension; Ouabain; Pregnancy; Pregnancy Complications, Cardiovascular; Radioimmunoassay; Sodium-Potassium-Exchanging ATPase | 1984 |
[Affinity chromatographic study of the changes in the endogenous Na+-K+-ATPase inhibitor during sodium loading in man].
Topics: Animals; Chromatography, Affinity; Dogs; Enzymes, Immobilized; Humans; Hypertension; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase | 1984 |
[Active calcium and sodium transport by cardiac plasma membranes in the genetically hypertensive rat].
Topics: Animals; Calcium; Calmodulin; Cell Membrane; Hypertension; In Vitro Techniques; Ion Channels; Male; Myocardium; Nifedipine; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sodium; Sodium-Potassium-Exchanging ATPase | 1984 |
[Circulating inhibitor of the Na+-K+ pump in essential hypertension. Physiological and pharmacological variations].
Topics: Animals; Erythrocytes; Humans; Hypertension; In Vitro Techniques; Ion Channels; Male; Ouabain; Potassium; Rats; Rats, Inbred Strains; Sodium; Sodium-Potassium-Exchanging ATPase | 1984 |
Plasma endogenous sodium pump inhibitor in essential hypertension.
Topics: Animals; Blood Platelets; Blood Pressure; Cerebral Ventricles; Erythrocytes; Humans; Hypertension; Male; Ouabain; Protein Binding; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Sodium-Potassium-Exchanging ATPase | 1983 |
Investigation of the endogenous Na+-pump inhibitor in essential hypertension and blood volume expansion.
Topics: Acromegaly; Adult; Animals; ATPase Inhibitory Protein; Blood Proteins; Blood Volume; Digitalis; Erythrocytes; Female; Humans; Hypertension; Ion Channels; Kidney Failure, Chronic; Male; Middle Aged; Ouabain; Plants, Medicinal; Plants, Toxic; Proteins; Rats; Receptors, Drug; Sodium; Sodium-Potassium-Exchanging ATPase | 1984 |
Effects of changes in dietary sodium intake on normotensive subjects with and without a genetic predisposition to essential hypertension.
Topics: Adenosine Triphosphate; Adult; Animals; Biological Assay; Biological Transport; Diet, Sodium-Restricted; Disease Susceptibility; Dogs; Erythrocytes; Humans; Hypertension; Kidney; Luminescent Measurements; Male; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase; Time Factors | 1984 |
The effect of antihypertensive therapy on abnormal leucocyte sodium transport in essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amiloride; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Diastole; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Leukocytes; Male; Middle Aged; Ouabain; Sodium; Sodium Chloride Symporter Inhibitors | 1981 |
Leucocyte membrane sodium transport in normotensive populations: dissociation of abnormalities of sodium efflux from raised blood-pressure.
Topics: Adult; Blood Pressure; Cell Membrane; Cell Membrane Permeability; Female; Humans; Hypertension; Leukocytes; Male; Ouabain; Sodium | 1982 |
Test for circulating Na+-K+ ATPase inhibitors.
Topics: Biological Assay; Firefly Luciferin; Humans; Hypertension; Luciferases; Luminescent Measurements; Ouabain; Sodium-Potassium-Exchanging ATPase | 1983 |
Ouabain-insensitive net sodium influx in erythrocytes of normotensive and essential hypertensive humans.
Topics: Biological Transport, Active; Erythrocytes; Humans; Hypertension; Kinetics; Ouabain; Reference Values; Sodium | 1982 |
Clinical and biochemical approach of a circulating Na+-pump inhibitor.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Benzothiadiazines; Blood Platelets; Diuretics; Erythrocytes; Female; Humans; Hypertension; Ion Channels; Male; Middle Aged; Ouabain; Serotonin; Sodium; Sodium Chloride Symporter Inhibitors; Sodium-Potassium-Exchanging ATPase | 1984 |
Plasma sodium pump inhibitor in essential hypertension and normotensive subjects with hypertensive heredity.
Topics: Adult; Binding, Competitive; Biological Transport, Active; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Peptides; Potassium; Renin; Sodium; Sodium-Potassium-Exchanging ATPase | 1984 |
Forearm vasoconstrictor response to ouabain: studies in patients with mild and moderate essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Epinephrine; Forearm; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Ouabain; Regional Blood Flow; Renin; Sodium-Potassium-Exchanging ATPase; Vascular Resistance; Vasoconstriction | 1984 |
Calmodulin reduces ouabain-sensitive ATPase of cardiac sarcolemmal membranes: high reduction in spontaneously hypertensive rats.
Topics: Adenosine Triphosphatases; Animals; Calcium; Calmodulin; Heart; Hypertension; In Vitro Techniques; Myocardium; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcolemma | 1984 |
Venous volume in offspring of hypertensive patients.
Topics: Adult; Blood Pressure; Blood Volume; Cardiomegaly; Heart Rate; Humans; Hypertension; Male; Ouabain | 1984 |
Inherited defect in a Na+, K-co-transport system in erythrocytes from essential hypertensive patients.
Topics: Binding Sites; Biological Transport; Erythrocyte Membrane; Erythrocytes; Humans; Hypertension; Ouabain; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase | 1980 |
Studies on the role of sodium-potassium-activated ATPase as determinant of vascular reactivity in Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Animals; Barium; Biological Transport, Active; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; In Vitro Techniques; Norepinephrine; Ouabain; Rats; Sodium-Potassium-Exchanging ATPase | 1980 |
Effect of sodium-potassium-dependent ATPase inhibition on noradrenaline-activated calcium sensitivity of mesenteric resistance vessels in adult spontaneously hypertensive rats.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Female; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Rats; Sodium-Potassium-Exchanging ATPase | 1980 |
Na-K-ATPase in erythrocyte ghosts is not a marker for primary hypertension.
Topics: Adult; Cushing Syndrome; Erythrocyte Membrane; Erythrocytes; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Immune Sera; Male; Middle Aged; Ouabain; Sodium-Potassium-Exchanging ATPase | 1981 |
Na countertransport and cotransport in human red cells: function, dysfunction, and genes in essential hypertension.
Topics: 4-Chloromercuribenzenesulfonate; Biological Transport, Active; Erythrocytes; Furosemide; Genes; Humans; Hypertension; Lithium; Ouabain; Phloretin; Potassium; Sodium | 1981 |
Cation fluxes and (Na+ + K+)-activated ATPase activity in erythrocytes of patients with essential hypertension.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine Triphosphate; Adult; Blood Pressure; Cold Temperature; Erythrocytes; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Ouabain; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase | 1981 |
A genetic approach to the geography of hypertension : examination of Na+ - K+ cotransport in Ivory Coast Africans.
Topics: Adolescent; Adult; Aged; Biological Transport, Active; Cote d'Ivoire; Erythrocytes; Female; France; Furosemide; Humans; Hypertension; Male; Middle Aged; Ouabain; Potassium; Sodium | 1981 |
Furosemide and bumetanide-sensitive Na+ fluxes in erythrocytes from genetically hypertensive rats (SHR).
Topics: 4-Chloromercuribenzenesulfonate; Animals; Biological Transport, Active; Bumetanide; Erythrocytes; Furosemide; Genetic Markers; Hypertension; Male; Ouabain; Potassium; Rats; Rats, Inbred Strains; Sodium; Species Specificity | 1981 |
A factor in food which impairs Na+-K+-ATPase in vitro.
Topics: Cacao; Food Analysis; Humans; Hypertension; In Vitro Techniques; Ouabain; Sodium-Potassium-Exchanging ATPase; Tannins; Tea; Vegetables | 1982 |
Humoral factors and the sodium-potassium pump in low renin hypertension.
Topics: Animals; Blood Vessels; Cerebral Ventricles; Hypertension; Ion Channels; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Renin; Rubidium; Sodium-Potassium-Exchanging ATPase | 1982 |
A circulating inhibitor of (Na+ + K+)ATPase associated with essential hypertension.
Topics: Adult; Aged; Calcium; Humans; Hypertension; Male; Middle Aged; Ouabain; Sodium-Potassium-Exchanging ATPase; Vanadium; Water-Electrolyte Balance | 1982 |
Erythrocyte membrane sodium transport in patients with treated and untreated essential hypertension.
Topics: Adult; Erythrocyte Membrane; Erythrocytes; Humans; Hypertension; In Vitro Techniques; Middle Aged; Ouabain; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase | 1983 |
Measurement of digitalis-like compound in plasma: application in studies of essential hypertension.
Topics: Adolescent; Adult; Aged; Binding, Competitive; Child; Digitalis Glycosides; Erythrocyte Membrane; Erythrocytes; Female; Humans; Hypertension; Ion Channels; Male; Middle Aged; Ouabain; Sodium | 1983 |
Endogenous digitalis-like compound in essential hypertension.
Topics: Adult; Aged; Digitalis Glycosides; Female; Humans; Hypertension; Ion Channels; Male; Middle Aged; Ouabain; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase | 1983 |
Circulating digitalis-like compounds in essential hypertension.
Topics: Adult; Aged; Animals; Blood Platelets; Cardiovascular System; Digitalis Glycosides; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Rats; Serotonin; Sodium; Sodium-Potassium-Exchanging ATPase | 1984 |
Ouabain-binding and 86rubidium-uptake in lymphocytes of normal and borderline hypertensive subjects.
Topics: Adult; Binding Sites; Humans; Hypertension; Ion Channels; Lymphocytes; Male; Ouabain; Potassium; Radioisotopes; Rubidium; Sodium | 1983 |
Circulating digitalis-like substance is increased in DOCA-salt hypertension.
Topics: Animals; Chromatography, Gel; Cross Reactions; Desoxycorticosterone; Digitalis Glycosides; Digoxin; Hypertension; Male; Ouabain; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Drug; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 1984 |
The role of a humoral sodium-potassium pump inhibitor in low-renin hypertension.
Topics: Animals; Biological Transport, Active; Disease Models, Animal; Dogs; Humans; Hypertension; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Renin; Rubidium; Sodium | 1983 |
Membrane potential of vascular smooth muscle and hypertension in spontaneously hypertensive rats.
Topics: Aging; Animals; Blood Pressure; Captopril; Hypertension; Male; Membrane Potentials; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium | 1984 |
Noradrenaline: a circulating inhibitor of sodium transport.
Topics: Biological Transport, Active; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Leukocytes; Male; Norepinephrine; Ouabain; Sodium | 1984 |
Sodium-potassium pump sites, as assessed by [3H]-ouabain binding, in aorta and caudal artery of normotensive and spontaneously hypertensive rats.
Topics: Animals; Aorta; Arteries; Binding Sites; Hypertension; Kinetics; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Rats, Inbred Strains; Sodium; Tail; Tritium | 1984 |
Ouabain-resistant, frusemide-sensitive sodium efflux in human lymphocytes: a comparison of normotensive and hypertensive subjects.
Topics: Adult; Biological Transport, Active; Female; Furosemide; Humans; Hypertension; In Vitro Techniques; Lymphocytes; Male; Ouabain; Sodium | 1984 |
Does the natriuretic hormone play a role in hypertension in South African blacks?
Topics: Adult; Black People; Dose-Response Relationship, Drug; Erythrocyte Count; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Potassium; Sodium; South Africa | 1984 |
Centrally-induced vasopressor responses to ouabain are augmented in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cerebral Ventricles; Heart Rate; Hypertension; Injections, Intraventricular; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spinal Cord; Sympathetic Nervous System | 1984 |
Potassium influx into erythrocytes in essential hypertension.
Topics: Adult; Biological Transport; Erythrocytes; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Ouabain; Potassium | 1984 |
Differential stimulation of synaptosomal norepinephrine uptake by high salt diet in Dahl rats.
Topics: Animals; Diet; Hypertension; Hypothalamus; Norepinephrine; Ouabain; Rats; Sodium Chloride; Synaptosomes | 1984 |
Abnormal leucocyte sodium transport in Chinese patients with essential hypertension and their normotensive offsprings.
Topics: Adult; Biological Transport; Blood Pressure; Female; Humans; Hypertension; Leukocytes; Male; Middle Aged; Ouabain; Potassium; Sodium | 1984 |
Evidence against a circulating ouabain-like transport inhibitor as a cause of increased red cell sodium in essential hypertension.
Topics: Adult; Biological Transport; Blood Pressure; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Potassium; Sodium | 1984 |
Sodium transport by leucocytes and erythrocytes in hypertensive subjects and their normotensive relatives.
Topics: Adult; Biological Transport; Erythrocytes; Humans; Hypertension; Leukocytes; Male; Middle Aged; Ouabain; Sodium | 1984 |
The effect of pregnancy and pregnancy induced hypertension on active sodium transport in the erythrocyte.
Topics: Adolescent; Adult; Biological Transport, Active; Cell Membrane Permeability; Erythrocytes; Female; Humans; Hypertension; Kinetics; Ouabain; Potassium; Pregnancy; Pregnancy Complications, Cardiovascular; Sodium | 1983 |
Hypertension: cation transport and the physical properties of erythrocytes.
Topics: Adult; Animals; Blood Sedimentation; Cations; Erythrocytes; Female; Furosemide; Humans; Hypertension; In Vitro Techniques; Male; Middle Aged; Ouabain; Potassium; Rats; Rats, Inbred Strains; Sodium | 1983 |
Ouabain-binding and 86rubidium-uptake in lymphocytes of normal and borderline hypertensive subjects.
Topics: Adult; Humans; Hypertension; Lymphocytes; Male; Ouabain; Potassium; Radioisotopes; Rubidium; Sodium | 1983 |
Investigations on the Na+, K+-pump in erythrocytes of patients with renal hypertension.
Topics: Adult; Biological Transport, Active; Chronic Disease; Erythrocytes; Female; Humans; Hypertension; Hypertension, Renal; Kidney Diseases; Male; Middle Aged; Ouabain; Potassium; Sodium | 1984 |
Natriuretic hormone--the missing link in low renin hypertension?
Topics: Animals; Blood Vessels; Humans; Hypertension; Natriuretic Agents; Ouabain; Proteins; Renin | 1982 |
A functional abnormality of the forearm resistance vessels in men with primary hypertension.
Topics: Adult; Chlorthalidone; Forearm; Humans; Hypertension; Middle Aged; Ouabain; Regional Blood Flow; Sodium; Vascular Resistance | 1983 |
Inhibition of the arteriolar smooth muscle NA+ -K+-pump induces an enhanced vasoconstriction in borderline but not in established essential hypertension.
Topics: Adolescent; Adult; Aged; Arterioles; Biological Transport, Active; Forearm; Humans; Hypertension; In Vitro Techniques; Male; Middle Aged; Muscle, Smooth, Vascular; Ouabain; Potassium; Regional Blood Flow; Sodium; Vascular Resistance; Vasoconstriction | 1983 |
Genetic markers in spontaneously hypertensive rats.
Topics: Animals; Blood Proteins; Cell Membrane Permeability; Clemastine; Disease Models, Animal; Erythrocyte Membrane; Genetic Markers; Hypertension; Ouabain; Rats; Rats, Inbred Strains; Sodium; Species Specificity | 1981 |
Abnormal erythrocyte Na+ K+ cotransport system, a proposed genetic marker of essential hypertension.
Topics: Biological Transport, Active; Cell Membrane Permeability; Erythrocytes; Furosemide; Genetic Markers; Humans; Hypertension; Ouabain; Potassium; Sodium | 1981 |
Further studies of angiopathic serum factor in perinephritic hypertensive dogs.
Topics: Animals; Aorta; Blood Proteins; Creatinine; Culture Techniques; Dinoprost; Dogs; Dose-Response Relationship, Drug; Hexosamines; Hypertension; Male; Ouabain; Potassium; Prostaglandins F; Sodium; Water | 1981 |
Erythrocytic sodium ion transport systems in primary and secondary hypertension of the rat.
Topics: Animals; Bumetanide; Erythrocytes; Female; Furosemide; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Intracellular Fluid; Male; Ouabain; Potassium; Rats; Sodium; Sodium Chloride | 1982 |
Blood pressure regulation and characteristics of small arteries in hypertension.
Topics: Animals; Arteries; Blood Pressure; Calcium; Hypertension; Muscle Contraction; Ouabain; Rats; Rats, Inbred Strains | 1982 |
Ion-selective electrode studies of cell Na components in vascular smooth muscle of WKY and SHR.
Topics: Animals; Electrodes; Hypertension; Male; Methods; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Rats, Inbred Strains; Sodium; Temperature | 1982 |
[Studies on dose-dependent effect of ouabain on right ventricular function and pulmonary circulation].
Topics: Animals; Dogs; Dose-Response Relationship, Drug; Hypertension; In Vitro Techniques; Myocardial Contraction; Ouabain; Pulmonary Circulation; Pulmonary Heart Disease; Vascular Resistance; Vasoconstriction | 1982 |
Hypotensive effects of cardiac glycosides in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cardiac Glycosides; Digitoxin; Hypertension; Injections, Intra-Arterial; Injections, Intraperitoneal; Intubation, Gastrointestinal; Male; Ouabain; Pressoreceptors; Rats | 1980 |
Decrease in [3H]ouabain binding sites in heart and brain from spontaneously hypertensive rats.
Topics: Animals; Binding Sites; Brain; Hypertension; Kinetics; Male; Myocardium; Organ Specificity; Ouabain; Rats; Tritium | 1981 |
Increased intralymphocytic sodium content in essential hypertension: an index of impaired Na+ cellular metabolism.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cells, Cultured; Child; Female; Humans; Hypertension; Lymphocytes; Male; Middle Aged; Ouabain; Sodium; Time Factors | 1981 |
Racial differences in red cell cation transport and their relationship to essential hypertension.
Topics: Adult; Aged; Black or African American; Erythrocytes; Humans; Hypertension; Middle Aged; Ouabain; Radioisotopes; Rubidium; Sodium; West Indies; White People | 1981 |
Comparison of outward and inward Na+/K+ cotransport-mediated fluxes in erythrocytes of essential hypertensive patients. Preliminary results.
Topics: Adult; Biological Transport, Active; Erythrocytes; Furosemide; Humans; Hypertension; Ouabain; Potassium; Sodium | 1981 |
Vascular reactivity in hypertension: altered effect of ouabain.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Hypertension; Manganese; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Ouabain; Rats | 1980 |
Arterial wall "waterlogging" accompanying chronic digoxin treatment in dogs.
Topics: Animals; Blood Pressure; Digoxin; Dogs; Hypertension; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Ouabain; Sodium; Time Factors; Water | 1980 |
An inherited sodium ion-potassium ion cotransport defect in essential hypertension.
Topics: Biological Transport, Active; Erythrocytes; Furosemide; Humans; Hypertension; In Vitro Techniques; Ouabain; Potassium; Sodium | 1980 |
Vascular Na+-K+ pump activity in Dahl S and R rats.
Topics: Animals; Blood Vessels; Hypertension; Male; Ouabain; Potassium; Radioisotopes; Rats; Rubidium; Sodium; Sodium Chloride | 1980 |
Natriuretic Factors and Hypertension. Proceedings of a satellite symposium to the 14th ISH meeting. Sevilla, Spain, June 19-20, 1992.
Topics: Animals; Humans; Hypertension; Natriuretic Agents; Ouabain; Sodium-Potassium-Exchanging ATPase | 1993 |
Role of ouabain-like factors in hypertension: effects of ouabain and certain endogenous ouabain-like factors in hypertension.
Topics: Animals; Blood Pressure; Cardiac Output; Diet, Sodium-Restricted; Enzyme-Linked Immunosorbent Assay; Hypertension; Injections, Intraperitoneal; Kidney; Male; Ouabain; Radioimmunoassay; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Vasoconstriction | 1993 |
Hypothalamic Na+,K(+)-ATPase inhibitor constricts pulmonary arteries of spontaneously hypertensive rats.
Topics: Animals; Dose-Response Relationship, Drug; Hypertension; Hypothalamus; In Vitro Techniques; Male; Ouabain; Phentolamine; Pulmonary Artery; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Vasoconstriction; Verapamil | 1993 |
Comparison of low-molecular-weight plasma and urine Na-K-ATPase inhibitors/hypertensive factors.
Topics: Animals; Binding Sites; Chromatography, High Pressure Liquid; Digoxin; Humans; Hypertension; Kinetics; Molecular Weight; Ouabain; Potassium; Rabbits; Radioimmunoassay; Sodium-Potassium-Exchanging ATPase; Vasoconstriction; Vasoconstrictor Agents | 1993 |
Role of brain ouabain-like activity in the central effects of sodium in rats.
Topics: Animals; Blood Pressure; Hypertension; Hypothalamus; Injections, Intraventricular; Kidney; Male; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium, Dietary; Sympathetic Nervous System | 1993 |
Characteristics of a ouabain-like factor from Milan hypertensive rats.
Topics: Adrenal Glands; Animals; Binding Sites; Calcium-Transporting ATPases; Cattle; Chromatography, High Pressure Liquid; Dogs; Hypertension; Hypothalamus; In Vitro Techniques; Kidney; Male; Ouabain; Potassium; Rats; Sodium-Potassium-Exchanging ATPase | 1993 |
Endothelium-dependent relaxation of small arteries from essential hypertensive patients: mechanisms and comparison with normotensive subjects and with responses of vessels from spontaneously hypertensive rats.
Topics: Acetylcholine; Adult; Animals; Apamin; Arginine; Arterioles; Charybdotoxin; Endothelium, Vascular; Humans; Hypertension; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Middle Aged; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Ouabain; Potassium Chloride; Rats; Rats, Inbred SHR; Scorpion Venoms; Tolbutamide; Vasoconstriction | 1995 |
Insulin resistance is associated with high plasma ouabain-like immunoreactivity concentration in NIDDM.
Topics: Aged; Antibody Specificity; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Humans; Hypertension; Insulin; Insulin Infusion Systems; Insulin Resistance; Male; Middle Aged; Ouabain; Radioimmunoassay; Reference Values; Systole | 1995 |
[Decrease in adenylate cyclase sensitivity to sodium ions in lymphocytes of patients with arterial hypertension].
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Catecholamines; Enzyme Activation; GTP-Binding Proteins; Humans; Hypertension; Isoproterenol; Lymphocytes; Male; Middle Aged; Ouabain; Sodium | 1995 |
Effect of insulin on acetylcholine-induced vasodilation in normotensive subjects and patients with essential hypertension.
Topics: Acetylcholine; Arginine; Case-Control Studies; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Hypertension; Insulin; Male; Middle Aged; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Ouabain; Regional Blood Flow; Sodium-Potassium-Exchanging ATPase; Time Factors; Vasodilation; Vasodilator Agents | 1995 |
Endothelial stimulation of sodium pump in cultured vascular smooth muscle.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Culture Media; Endothelium, Vascular; Hypertension; Male; Muscle, Smooth, Vascular; Ouabain; Phosphorus Radioisotopes; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rubidium Radioisotopes; Sodium; Sodium-Potassium-Exchanging ATPase | 1995 |
Brain 'ouabain,' sodium, and arterial baroreflex in spontaneously hypertensive rats.
Topics: Animals; Arteries; Baroreflex; Brain; Diet, Sodium-Restricted; Heart Rate; Hypertension; Kidney; Male; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sympathetic Nervous System | 1995 |
Effect of Na,K-ATPase inhibition on cytosolic free calcium ions in vascular smooth muscle cells of spontaneously hypertensive and normotensive rats.
Topics: Animals; Aorta; Calcium; Cells, Cultured; Hypertension; Male; Membrane Potentials; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase | 1994 |
Depressed cheek cell sodium transport in human hypertension.
Topics: Amiloride; Biological Transport; Body Mass Index; Bumetanide; Carrier Proteins; Cheek; Epithelium; Female; Humans; Hypertension; Male; Middle Aged; Mouth Mucosa; Ouabain; Protons; Sodium; Sodium Channels; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase | 1994 |
Human hypertensive placenta contains an increased amount of Na,K-ATPase with higher affinity for cardiac glycosides.
Topics: Adult; Cardiac Glycosides; Female; Humans; Hypertension; Microsomes; Ouabain; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular | 1994 |
Ouabain-induced hypertension in the rat: relationships among plasma and tissue ouabain and blood pressure.
Topics: Adrenalectomy; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Kidney; Male; Ouabain; Rats; Rats, Sprague-Dawley; Sodium | 1994 |
Increased Na(+)-K+ pump number and decreased pump activity in soleus muscles in SHR.
Topics: Aging; Animals; Electrolytes; Epinephrine; Hindlimb; Hypertension; Insulin; Male; Membrane Potentials; Muscle Development; Muscles; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rubidium; Sodium-Potassium-Exchanging ATPase | 1994 |
Immunization of Dahl SS/jr rats with an ouabain conjugate mitigates hypertension.
Topics: Animals; Antibodies; Blood Pressure; Hypertension; Immunization; Ouabain; Rats; Rats, Inbred Strains; Sodium Chloride; Urease | 1994 |
Na,K-ATPase from placenta of women with pregnancy-induced hypertension exhibits an increased affinity for cardiac glycosides.
Topics: Anthracenes; Cardiac Glycosides; Female; Fluorescent Dyes; Humans; Hypertension; In Vitro Techniques; Membranes; Microsomes; Ouabain; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Sodium-Potassium-Exchanging ATPase | 1994 |
Nuclear magnetic resonance measurement of intracellular sodium in the perfused normotensive and spontaneously hypertensive rat heart.
Topics: Animals; Cardiac Pacing, Artificial; Hypertension; Intracellular Membranes; Magnetic Resonance Spectroscopy; Male; Myocardium; Ouabain; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Sodium | 1994 |
Reduced cytosolic free sodium concentration in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Animals; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Hypertension; Ionomycin; Male; Muscle, Smooth, Vascular; Ouabain; Propionates; Rats; Rats, Inbred SHR; Rats, Wistar; Sodium | 1994 |
Sodium transport activity in cheek epithelial cells from adolescents at increased risk of hypertension.
Topics: Adolescent; Amiloride; Biological Transport; Cheek; Female; Humans; Hypertension; Male; Mouth Mucosa; Ouabain; Protons; Risk Factors; Sex Characteristics; Sodium; Sodium-Hydrogen Exchangers | 1994 |
Norepinephrine-induced relaxations in rat aorta mediated by endothelial beta adrenoceptors. Impairment by ageing and hypertension.
Topics: Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Hypertension; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Norepinephrine; Ouabain; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Yohimbine | 1994 |
Brain "ouabain" mediates the sympathoexcitatory and hypertensive effects of high sodium intake in Dahl salt-sensitive rats.
Topics: Animals; Blood Pressure; Brain; Heart Rate; Hypertension; Immunoglobulin Fab Fragments; Kidney; Male; Ouabain; Rats; Sodium, Dietary; Sympathetic Nervous System | 1994 |
Erythrocyte Na-K-Cl cotransport activity in low renin essential hypertensive patients. A 23Na nuclear magnetic resonance study.
Topics: Adult; Biological Transport, Active; Blood Pressure; Carrier Proteins; Cell Membrane Permeability; Chlorides; Erythrocytes; Humans; Hypertension; Kallikreins; Magnetic Resonance Spectroscopy; Male; Middle Aged; Ouabain; Potassium; Renin; Sodium; Sodium Isotopes; Sodium-Potassium-Chloride Symporters; Sodium, Dietary | 1994 |
Red cell ouabain-resistant Na+ and K+ transport in Wistar, Brown Norway and spontaneously hypertensive rats.
Topics: Animals; Bumetanide; Cell Membrane Permeability; Drug Resistance; Erythrocytes; Hypertension; Ion Transport; Male; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Wistar; Rubidium; Sodium | 1993 |
Role of ouabainlike compound in rats with reduced renal mass-saline hypertension.
Topics: Animals; Blood Pressure; Hypertension; Male; Nephrectomy; Ouabain; Radioimmunoassay; Rats; Rats, Wistar; Sodium Chloride | 1994 |
Increased heart microsomal Na(+) K(+)-transporting ATPase activity by tetrandrine in spontaneously hypertensive rats.
Topics: Alkaloids; Animals; Antihypertensive Agents; Benzylisoquinolines; Calcium Chloride; Hypertension; Microsomes; Mitochondria, Heart; Myocardium; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase | 1993 |
Increased cytosolic free sodium concentrations in platelets from type 2 (non-insulin-dependent) diabetic patients is associated with hypertension.
Topics: Adult; Aged; Aged, 80 and over; Blood Platelets; Cytosol; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Sodium; Thrombin | 1993 |
Membrane fluidity of erythrocytes and its modulation by ouabain in essential hypertension--an electron paramagnetic resonance study.
Topics: Electron Spin Resonance Spectroscopy; Erythrocytes; Female; Humans; Hypertension; Male; Membrane Fluidity; Middle Aged; Ouabain; Spin Labels | 1993 |
Does plasma immunoreactive ouabain originate from the adrenal gland?
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Cushing Syndrome; Female; Humans; Hyperaldosteronism; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Ouabain; Pheochromocytoma; Radioimmunoassay; Reference Values; Renal Dialysis | 1994 |
Increased cytosolic sodium and reduced Na,K-ATPase activity in transgenic rats.
Topics: Animals; Animals, Genetically Modified; Cells, Cultured; Cytosol; Disease Models, Animal; Hypertension; Kinetics; Lymphocytes; Mice; Ouabain; Rats; Rats, Sprague-Dawley; Renin; Sodium; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence; Time Factors | 1994 |
Ouabain in plasma from spontaneously hypertensive rats.
Topics: Animals; Calcium, Dietary; Chromatography, High Pressure Liquid; Hypertension; Male; Ouabain; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rubidium Radioisotopes; Tritium | 1994 |
Erythrocytic ouabain-sensitive sodium efflux rate constant in pregnancy.
Topics: Adult; Analysis of Variance; Biological Transport, Active; Blood Pressure; Creatinine; Cross-Sectional Studies; Erythrocytes; Female; Humans; Hypertension; Ouabain; Potassium; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Random Allocation; Sodium; Sodium, Dietary; White People | 1993 |
Long-term ouabain administration produces hypertension in rats.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Drug Administration Schedule; Hemodynamics; Hypertension; Injections, Intraperitoneal; Male; Nephrectomy; Ouabain; Rats; Rats, Wistar; Time Factors | 1993 |
Regulation of Na+/H+ exchange in mesenteric arteries from spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Captopril; Carrier Proteins; Hydrogen-Ion Concentration; Hypertension; Male; Mesenteric Arteries; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Hydrogen Exchangers | 1993 |
[The activity and properties of K-pNPphosphatase in membrane preparations of erythrocytes with different polypeptide compositions in Wistar, Wistar-Kyoto and SHR strain rats].
Topics: 4-Nitrophenylphosphatase; Adenosine Triphosphate; Animals; Calcium; Erythrocyte Membrane; Hypertension; Ouabain; Peptides; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 1993 |
Morpho-functional modifications of human syncytiotrophoblast plasma membrane during pregnancy induced hypertension.
Topics: Adult; Case-Control Studies; Cell Membrane; Enzyme Inhibitors; Female; Freeze Fracturing; Giant Cells; Humans; Hypertension; Kinetics; Ouabain; Pregnancy; Pregnancy Complications, Cardiovascular; Protein Conformation; Sodium-Potassium-Exchanging ATPase; Trophoblasts | 1995 |
Immunoreactive endogenous ouabain in primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels.
Topics: Aldosterone; Blood Pressure; Dihydroergotoxine; Dopamine Agonists; Dopamine Antagonists; Female; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Male; Metoclopramide; Middle Aged; Ouabain; Renin; Retrospective Studies | 1995 |
Chronic ouabain infusion does not cause hypertension in sheep.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; Female; Heart Rate; Hypertension; Infusions, Intravenous; Ouabain; Potassium; Pulse; Rats; Renin; Renin-Angiotensin System; Sheep; Sodium; Time Factors | 1996 |
Responses of cremasteric arterioles of spontaneously hypertensive rats to changes in extracellular K+ concentration.
Topics: Animals; Arterioles; Hypertension; Muscle, Skeletal; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase; Vasomotor System | 1995 |
Vascular responses to sodium nitroprusside in the human fetal-placental circulation.
Topics: Adolescent; Adult; Arginine; Blood Pressure; Dinoprost; Enzyme Inhibitors; Female; Fetal Growth Retardation; Fetus; Humans; Hypertension; In Vitro Techniques; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Ouabain; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Vasoconstriction; Vasodilation | 1995 |
Blockade of brain "ouabain" prevents sympathoexcitatory and pressor responses to high sodium in SHR.
Topics: Air; Animals; Blood Pressure; Brain; Diet, Sodium-Restricted; Guanabenz; Hypertension; Immunoglobulin Fab Fragments; Injections, Intraventricular; Male; Ouabain; Physical Stimulation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System | 1996 |
Effect of ageing and hypertension on endothelial modulation of ouabain-induced contraction and sodium pump activity in the rat aorta.
Topics: Aging; Animals; Aorta; Blood Pressure; Endothelium, Vascular; Hypertension; In Vitro Techniques; Male; Norepinephrine; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase; Vasoconstriction; Vasodilation | 1996 |
Ouabainlike compound in hypertension associated with ectopic corticotropin syndrome.
Topics: ACTH Syndrome, Ectopic; Chromatography, High Pressure Liquid; Humans; Hypertension; Lung Neoplasms; Male; Middle Aged; Ouabain | 1996 |
Reversal of sodium pump inhibitor induced vascular smooth muscle contraction with digibind. Stoichiometry and its implications.
Topics: Animals; Aorta; Digoxin; Enzyme Inhibitors; Female; Humans; Hypertension; Immunoglobulin Fab Fragments; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Rabbits; Sodium-Potassium-Exchanging ATPase | 1996 |
Ouabain amplifies contractile responses to phenylephrine in rat tail arteries in hypertension.
Topics: Animals; Arteries; Drug Synergism; Enzyme Inhibitors; Hypertension; Male; Ouabain; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Vasoconstriction; Vasoconstrictor Agents | 1995 |
Role of endogenous ouabain-like substance during graded exercise in hypertensive individuals.
Topics: Adult; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Ouabain; Physical Exertion; Reference Values | 1996 |
Effect of insulin on norepinephrine overflow at peripheral sympathetic nerve endings in young spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Buffers; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Electric Stimulation; Enzyme Inhibitors; Hypertension; Insulin; Male; Nerve Endings; Norepinephrine; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; Sympathetic Nervous System; Yohimbine | 1996 |
Brain "ouabain" and angiotensin II in salt-sensitive hypertension in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Brain; Guanabenz; Hemodynamics; Hypertension; Imidazoles; Immunoglobulin Fab Fragments; Injections, Intraventricular; Losartan; Male; Ouabain; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium Chloride, Dietary; Tetrazoles | 1996 |
Brain 'ouabain' in the median preoptic nucleus mediates sodium-sensitive hypertension in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; gamma-Globulins; Heart Rate; Hypertension; Immunoglobulin Fab Fragments; Injections, Intraventricular; Male; Ouabain; Preoptic Area; Rats; Rats, Inbred SHR; Rats, Wistar; Sodium Chloride; Sodium, Dietary; Stress, Physiological | 1997 |
The basis of higher Na+ transport by inner medullary collecting duct cells from Dahl salt-sensitive rats: implicating the apical membrane Na+ channel.
Topics: Animals; Cell Membrane; Cells, Cultured; Drug Resistance; Electric Conductivity; Hypertension; Ion Transport; Kidney Medulla; Kidney Tubules, Collecting; Kinetics; Ouabain; Phosphorylation; Rats; Rats, Inbred Strains; Sodium; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary | 1997 |
Ouabain and hypertension.
Topics: Animals; Humans; Hypertension; Ouabain; Sodium-Potassium-Exchanging ATPase | 1997 |
Vasodepressor effects of exercise are accompanied by reduced circulating ouabainlike immunoreactivity and normalization of nitric oxide synthesis.
Topics: Adult; Aged; Blood Pressure; Cardenolides; Chromatography, High Pressure Liquid; Diabetes Mellitus; Digoxin; Enzyme-Linked Immunosorbent Assay; Exercise; Female; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Nitrates; Nitric Oxide; Obesity; Ouabain; Saponins | 1997 |
Adrenocorticotropin-induced hypertension in rats: role of ouabain-like compound.
Topics: Adrenocorticotropic Hormone; Animals; Hypertension; Male; Ouabain; Potassium; Rats; Rats, Wistar | 1997 |
Modifications induced by plasma of gestational hypertensive women on the Na+/K+-ATPase obtained from human placenta.
Topics: Adult; Blood Proteins; Enzyme Inhibitors; Female; Humans; Hypertension; Kinetics; Ouabain; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Reference Values; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence | 1997 |
17 beta-(3-furyl)-5 beta-androstane-3 beta, 14 beta, 17 alpha-triol (PST 2238). A very potent antihypertensive agent with a novel mechanism of action.
Topics: Androstanols; Animals; Antihypertensive Agents; Blood Pressure; Enzyme Inhibitors; Hypertension; Kinetics; Molecular Structure; Ouabain; Rats; Rats, Mutant Strains; Sodium-Potassium-Exchanging ATPase | 1997 |
Effects of ouabain on vascular reactivity.
Topics: Animals; Blood Pressure; Hypertension; In Vitro Techniques; Male; Ouabain; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasoconstrictor Agents | 1997 |
Endogenous digoxin-like immunoactivity and diabetes mellitus: facts and hypotheses.
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Digoxin; Glucose; Humans; Hyperinsulinism; Hypertension; Immunoassay; Insulin; Insulin Secretion; Models, Biological; Ouabain | 1997 |
Angiotensin II mediates cell hypertrophy in vascular smooth muscle cultures from hypertensive Ren-2 transgenic rats by an amiloride- and furosemide-sensitive mechanism.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biological Transport; Cell Size; Cells, Cultured; Femoral Artery; Furosemide; Heterozygote; Hypertension; Hypertrophy; Male; Mice; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Sprague-Dawley; Renin; Rubidium | 1997 |
The role of sodium-potassium adenosine triphosphatase in the regulation of membrane fluidity of erythrocytes in spontaneously hypertensive rats: an electron paramagnetic resonance investigation.
Topics: Animals; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Hypertension; Male; Membrane Fluidity; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase | 1997 |
Exogenous ouabain is accumulated in the adrenals and mimics the kinetics of endogenous digitalis-like factor in rats.
Topics: Adrenal Cortex; Adrenalectomy; Animals; Autoradiography; Cardenolides; Cardiotonic Agents; Chromatography, High Pressure Liquid; Cross Reactions; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Kidney; Kinetics; Nephrectomy; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Saponins; Tissue Distribution; Tritium | 1998 |
Plasma marinobufagenin-like and ouabain-like immunoreactivity in adrenocorticotropin-treated rats.
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Body Weight; Bufanolides; Erythrocytes; Heart Rate; Hypertension; Immunoassay; Male; Ouabain; Rats; Rats, Inbred F344; Sarcolemma; Sodium; Sodium-Potassium-Exchanging ATPase; Systole | 1998 |
Aldosterone stimulates Na,K-ATPase activity in basolateral membrane of rat kidney.
Topics: Aldosterone; Animals; Binding Sites; Dactinomycin; Gene Expression Regulation, Enzymologic; Hypertension; Kidney Cortex; Ouabain; Rats; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Transcription, Genetic | 1998 |
Comparative study of the effects of ouabain and digoxin on blood pressure of rats.
Topics: Animals; Blood Pressure; Cardiotonic Agents; Digoxin; Disease Models, Animal; Hypertension; Male; Ouabain; Random Allocation; Rats; Rats, Sprague-Dawley | 1997 |
Both brain angiotensin II and "ouabain" contribute to sympathoexcitation and hypertension in Dahl S rats on high salt intake.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Body Weight; Brain; Cardiotonic Agents; Guanabenz; Hemodynamics; Hypertension; Nitroprusside; Ouabain; Phenylephrine; Rats; Rats, Inbred Dahl; Sodium Chloride; Stress, Physiological | 1998 |
Ouabain- and central sodium-induced hypertension depend on the ventral anteroventral third ventricle region.
Topics: Animals; Cerebral Ventricles; Drug Implants; Excitatory Amino Acid Agonists; Hypertension; Ibotenic Acid; Injections, Intraventricular; Male; Microinjections; Ouabain; Rats; Rats, Wistar; Saline Solution, Hypertonic; Sodium | 1999 |
PST 2238: A new antihypertensive compound that modulates Na,K-ATPase in genetic hypertension.
Topics: Androstanols; Animals; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Heart Rate; Hypertension; Kidney Medulla; Male; Mutation; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred Strains; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Transfection | 1999 |
Na-K-ATPase inhibitor dissociated from hypertension-associated plasma protein.
Topics: 4-Nitrophenylphosphatase; Animals; Binding, Competitive; Blood Proteins; Digoxin; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Femoral Artery; Humans; Hypertension; In Vitro Techniques; Male; Mass Spectrometry; Molecular Weight; Ouabain; Rabbits; Radioimmunoassay; Sodium-Potassium-Exchanging ATPase; Tritium; Vasoconstriction | 1999 |
Brain renin-angiotensin system and ouabain-induced sympathetic hyperactivity and hypertension in Wistar rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arteries; Baroreflex; Brain; Guanabenz; Heart; Hypertension; Injections, Intraventricular; Kidney; Lung; Male; Nervous System Diseases; Ouabain; Rats; Rats, Wistar; Renin-Angiotensin System; Stress, Physiological; Sympathetic Nervous System | 1999 |
Effects of chronic treatment with simvastatin on endothelial dysfunction in spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Cardiotonic Agents; Endothelium, Vascular; Enzyme Inhibitors; Follow-Up Studies; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Nitric Oxide Synthase; Nitroarginine; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Simvastatin; Vasodilation; Vasodilator Agents | 1999 |
Platelet sodium pump and sodium potassium cotransport activity in nonpregnant, normotensive, and hypertensive pregnant women.
Topics: Adult; Blood Platelets; Cardiotonic Agents; Female; Humans; Hypertension; Ouabain; Pregnancy; Pregnancy Complications, Cardiovascular; Proteinuria; Sodium-Potassium-Exchanging ATPase | 1999 |
Left ventricular mass, stroke volume, and ouabain-like factor in essential hypertension.
Topics: Adult; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Ouabain; Regression Analysis; Stroke Volume; Ventricular Function | 1999 |
Vasodilation to bradykinin is mediated by an ouabain-sensitive pathway as a compensatory mechanism for impaired nitric oxide availability in essential hypertensive patients.
Topics: Adaptation, Physiological; Adult; Antioxidants; Ascorbic Acid; Biological Availability; Bradykinin; Drug Combinations; Enzyme Inhibitors; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Ouabain; Reference Values; Vasodilation; Vasodilator Agents | 1999 |
Digoxin prevents ouabain and high salt intake-induced hypertension in rats with sinoaortic denervation.
Topics: Animals; Aorta; Blood Pressure; Cardiotonic Agents; Denervation; Digoxin; Hypertension; Male; Ouabain; Rats; Rats, Wistar; Sodium Chloride, Dietary; Sympathetic Nervous System | 1999 |
Increased Na(+)/H(+) exchanger isoform 1 activity in spontaneously hypertensive rats: lack of mutations within the coding region of NHE1.
Topics: Amiloride; Animals; Aorta; Cells, Cultured; Crosses, Genetic; DNA Mutational Analysis; DNA, Complementary; Female; Genetic Variation; Hypertension; Ion Transport; Male; Muscle Proteins; Muscle, Smooth, Vascular; Ouabain; Polymorphism, Single-Stranded Conformational; Protein Isoforms; Protons; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers | 2000 |
[The hypothalamic and brain stem mechanisms in the development of arterial hypertension during aging].
Topics: Aging; Animals; Blood Pressure; Brain Stem; Cardiotonic Agents; Electric Stimulation; Electrodes, Implanted; Hypertension; Hypothalamus; Norepinephrine; Ouabain; Rabbits; Rats; Rats, Wistar; Vasoconstrictor Agents | 2000 |
Nitric oxide synthase induction by ouabain in vascular smooth muscle cells from normotensive and hypertensive rats.
Topics: Animals; Blotting, Western; Calcimycin; Calcium; Calcium Channel Blockers; Cells, Cultured; Enzyme Induction; Enzyme Inhibitors; Hypertension; Interleukin-1; Intracellular Fluid; Ionophores; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ouabain; Rats; Rats, Inbred SHR; Rats, Wistar | 2000 |
Neuronal Fos-like immunoreactivity in ouabain-induced hypertension.
Topics: Animals; Blood Pressure; Hypertension; Immunohistochemistry; Injections, Subcutaneous; Locus Coeruleus; Male; Neurons; Ouabain; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reference Values; Supraoptic Nucleus | 2000 |
Liquid chromatography mass spectrometric analysis of ouabainlike factor in biological fluid.
Topics: Animals; Cardenolides; Cardiotonic Agents; Chromatography, Liquid; Digoxin; Humans; Hypertension; Mass Spectrometry; Ouabain; PC12 Cells; Rats; Saponins | 2000 |
Analysis of human ouabainlike compound by micellar electrokinetic chromatography.
Topics: Cardenolides; Cardiotonic Agents; Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Digoxin; Humans; Hypertension; Ouabain; Saponins | 2000 |
Differential regulation of the sodium pump alpha-subunit isoform gene by ouabain and digoxin in tissues of rats.
Topics: Animals; Blood Pressure; Cardiotonic Agents; Digoxin; DNA Primers; Gene Expression; Hypertension; Male; Ouabain; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Potassium-Exchanging ATPase | 2000 |
Application of supercritical fluid chromatography to characterize a labile digitalis-like factor.
Topics: Cardenolides; Chromatography, Gas; Chromatography, High Pressure Liquid; Digoxin; Enzyme Inhibitors; Humans; Hypertension; Kidney Failure, Chronic; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase | 2000 |
Reduced Na-K pump but increased Na-K-2Cl cotransporter in aorta of streptozotocin-induced diabetic rat.
Topics: Animals; Aorta; Biological Transport; Blotting, Western; Bumetanide; Carrier Proteins; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diuretics; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Isoenzymes; Male; Muscle Tonus; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase | 2001 |
AT(1) receptor blockers prevent sympathetic hyperactivity and hypertension by chronic ouabain and hypertonic saline.
Topics: Air Movements; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Chronic Disease; Guanabenz; Heart Rate; Hypertension; Injections, Intraventricular; Losartan; Male; Ouabain; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Saline Solution, Hypertonic; Stress, Physiological; Sympathetic Nervous System; Vasoconstrictor Agents | 2001 |
High salt intake and the brain renin--angiotensin system in Dahl salt-sensitive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Brain; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Hypertension; Immunoglobulin Fab Fragments; Injections, Intraventricular; Male; Ouabain; Peptidyl-Dipeptidase A; Radioimmunoassay; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium, Dietary; Spectrometry, Fluorescence | 2001 |
Marinobufagenin, an endogenous alpha-1 sodium pump ligand, in hypertensive Dahl salt-sensitive rats.
Topics: Animals; Blood Pressure; Bufanolides; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Hypertension; Isoenzymes; Kidney; Natriuresis; Ouabain; Rats; Rats, Inbred Dahl; Sodium; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary | 2001 |
Structure-activity relationships for the hypertensinogenic activity of ouabain: role of the sugar and lactone ring.
Topics: Animals; Blood Pressure; Cardiac Glycosides; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Hypertension; Infusions, Intravenous; Lactones; Magnetic Resonance Spectroscopy; Male; Ouabain; Rats; Rats, Sprague-Dawley; Rhamnose; Sodium-Potassium-Exchanging ATPase; Spectrophotometry, Ultraviolet; Steroids; Structure-Activity Relationship | 2001 |
Effects of ouabain on the growth and DNA synthesis of PC12 cells.
Topics: Animals; Cell Division; DNA; Enzyme Inhibitors; Genes, myc; Hypertension; Nerve Growth Factor; Ouabain; PC12 Cells; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase | 2001 |
Synaptic plasticity in sympathetic ganglia from acquired and inherited forms of ouabain-dependent hypertension.
Topics: Action Potentials; Animals; Blood Pressure; Digoxin; Disease Models, Animal; Electrophysiology; Humans; Hypertension; In Vitro Techniques; Long-Term Potentiation; Male; Neuronal Plasticity; Ouabain; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Superior Cervical Ganglion | 2001 |
Altered Na+-K+ pump activity and plasma lipids in salt-hypertensive Dahl rats: relationship to Atp1a1 gene.
Topics: Animals; Blood Pressure; Cholesterol; Enzyme Inhibitors; Erythrocytes; Hypertension; Ion Transport; Lipids; Male; Ouabain; Polymorphism, Genetic; Rats; Rats, Inbred Dahl; Rubidium; Sodium; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 2001 |
Expression of sodium pump isoforms and other sodium or calcium ion transporters in the heart of hypertensive patients.
Topics: Adult; Aged; Animals; Calcium-Transporting ATPases; Cell Membrane; Female; Heart Atria; Humans; Hypertension; Male; Middle Aged; Myocardium; Ouabain; Polymerase Chain Reaction; Protein Isoforms; RNA, Messenger; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 2001 |
Effects of small doses of ouabain on the arterial blood pressure of anesthetized hypertensive and normotensive rats.
Topics: Analysis of Variance; Animals; Blood Pressure; Cardiotonic Agents; Desoxycorticosterone; Disease Models, Animal; Hypertension; Hypertension, Renovascular; Male; Ouabain; Phenylephrine; Rats; Rats, Wistar; Vasoconstriction | 2001 |
Enhanced sympathoexcitatory and pressor responses to central Na+ in Dahl salt-sensitive vs. -resistant rats.
Topics: Adrenergic alpha-Agonists; Age Factors; Animals; Baroreflex; Blood Pressure; Brain; Guanabenz; Heart Rate; Hypertension; Injections, Intraventricular; Kidney; Male; Ouabain; Potassium; Rats; Rats, Inbred Dahl; Rats, Wistar; Sodium; Sodium, Dietary; Sympathetic Nervous System | 2001 |
The change and significance of the Na+-K+-ATPase alpha-subunit in ouabain-hypertensive rats.
Topics: Adrenal Glands; Animals; Binding Sites; Blood Pressure; Electrolytes; Enzyme Inhibitors; Erythrocytes; Hypertension; Male; Ouabain; Rats; Rats, Sprague-Dawley; Reference Values; Sodium-Potassium-Exchanging ATPase | 2001 |
Replacement of (alpha)1-Na-K-ATPase of Dahl rats by Milan rats lowers blood pressure but does not affect its activity.
Topics: Alleles; Animals; Animals, Genetically Modified; Blood Pressure; Enzyme Activation; Erythrocytes; Gene Targeting; Hypertension; Ion Transport; Male; Ouabain; Protein Subunits; Quantitative Trait, Heritable; Rats; Rats, Inbred Dahl; Rats, Inbred Strains; Rubidium Radioisotopes; Sodium Chloride, Dietary; Sodium Radioisotopes; Sodium-Potassium-Exchanging ATPase | 2001 |
Relationship between serum or tissue ouabain and blood pressure in 1k1c hypertensive rats.
Topics: Animals; Blood Pressure; Enzyme-Linked Immunosorbent Assay; Hypertension; Kidney; Male; Ouabain; Random Allocation; Rats; Rats, Sprague-Dawley | 2000 |
Alterations in phenylephrine-induced contractions and the vascular expression of Na+,K+-ATPase in ouabain-induced hypertension.
Topics: Animals; Aorta, Thoracic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Implants; Enzyme Inhibitors; Hypertension; Male; Mesenteric Artery, Superior; Ouabain; Phenylephrine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tail; Vasoconstriction; Vasoconstrictor Agents | 2002 |
The alpha1-Na/K pump does not mediate the involvement of ouabain in the development of hypertension in rats.
Topics: Animals; Aorta; Cations, Monovalent; Cells, Cultured; Dogs; Enzyme Inhibitors; Epithelial Cells; Humans; Hypertension; Isoenzymes; Kidney; Muscle, Smooth, Vascular; Ouabain; Rats; Sodium-Potassium-Exchanging ATPase | 2002 |
Abnormal sodium transport in leucocytes from patients with essential hypertension and the effect of treatment.
Topics: Adrenergic beta-Antagonists; Benzothiadiazines; Biological Transport, Active; Blood Pressure; Clonidine; Diuretics; Female; Humans; Hypertension; Hypertension, Malignant; Leukocytes; Male; Methyldopa; Ouabain; Sodium; Sodium Chloride Symporter Inhibitors; Water | 1975 |
Ouabain-sensitive and -insensitive ATPase activities in the kidney and the liver of spontaneously hypertensive rats.
Topics: Adenosine Triphosphatases; Animals; Female; Hypertension; Kidney; Liver; Male; Ouabain; Rats; Sex Factors; Species Specificity | 1979 |
Altered activity of the sodium-potassium pump in arteries of rats with steroid hypertension.
Topics: Animals; Arteries; Biological Transport, Active; Desoxycorticosterone; Hypertension; Male; Ouabain; Potassium; Rats; Rubidium; Sodium; Sodium-Potassium-Exchanging ATPase | 1978 |
Potassium relaxation of vascular smooth muscle from spontaneously hypertensive rats.
Topics: Animals; Arteries; Female; Hypertension; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ouabain; Potassium; Rats; Sodium-Potassium-Exchanging ATPase | 1979 |
Glass electrode measurement of net Na+ and K+ fluxes in erythrocytes of the spontaneously hypertensive rat.
Topics: Animals; Biological Transport; Blood Pressure; Erythrocytes; Hypertension; Kinetics; Male; Microelectrodes; Ouabain; Potassium; Potentiometry; Rats; Sodium | 1977 |
Evidence for enhanced Na transport in hypertension induced by DOCA in the rat.
Topics: Animals; Biological Transport; Desoxycorticosterone; Hypertension; Male; Ouabain; Potassium; Rats; Sodium | 1978 |
[Changes in noradrenaline-induced vasoconstriction through ouabain blockade of the transmembranal electrolyte distribution].
Topics: Animals; Blood Vessels; Drug Synergism; Ear; Electrolytes; Hypertension; Norepinephrine; Ouabain; Rabbits; Strophanthins; Vasoconstrictor Agents | 1978 |
Ion permeability of erythrocyte membrane in SHR [proceedings].
Topics: Animals; Cell Membrane Permeability; Cerebrovascular Disorders; Erythrocyte Membrane; Erythrocytes; Hypertension; Male; Ouabain; Rats; Sodium | 1977 |
An electrogenic sodium pump and baroreceptor function in normotensive and spontaneously hypertensive rats.
Topics: Action Potentials; Animals; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Hypertension; Lithium; Ouabain; Potassium; Pressoreceptors; Rats; Refractory Period, Electrophysiological; Sodium | 1976 |
[Disruption of erythrocyte membrane permeability for sodium and potassium ions in hypertension].
Topics: Adult; Aged; Cell Membrane Permeability; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Potassium; Sodium | 1976 |
[Disorder of erythrocyte membrane permeability in spontaneous genetic hypertension in rats].
Topics: Animals; Biological Transport; Blood Pressure; Cell Membrane Permeability; Erythrocytes; Hypertension; Male; Ouabain; Rats; Rats, Inbred Strains; Sodium | 1975 |
Differences in ouabain-induced natriuresis between isolated kidneys of Milan hypertensive and normotensive rats.
Topics: Animals; Glomerular Filtration Rate; Hydrochlorothiazide; Hypertension; Kidney; Natriuresis; Ouabain; Rats; Rats, Inbred Strains; Renal Circulation; Vascular Resistance | 1992 |
The ouabain-dependent Na(+)-K+ pump and the brain renin-angiotensin system.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Dogs; Female; Hypertension; Male; Ouabain; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Sodium-Potassium-Exchanging ATPase | 1992 |
Enhancement of vascular contractility by plasma substances obtained from pregnancy-induced hypertension.
Topics: Adult; Animals; Blood Pressure; Dogs; Female; Humans; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Pregnancy; Pregnancy Complications, Cardiovascular; Sodium-Potassium-Exchanging ATPase; Vanadates | 1992 |
Erythrocyte sodium ion transport system in DOC-salt, Goldblatt, and spontaneously hypertensive rats.
Topics: Animals; Bumetanide; Erythrocytes; Hypertension; Hypertension, Renovascular; Ion Transport; Male; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Sodium; Sodium-Potassium-Exchanging ATPase | 1992 |
Ouabainlike factor in Milan hypertensive rats.
Topics: Adrenal Glands; Animals; Brain; Cardenolides; Cattle; Digoxin; Erythrocytes; Hypertension; Hypothalamus; Kidney; Male; Ouabain; Potassium; Rats; Rats, Inbred Strains; Reference Values; Rubidium; Saponins; Sodium-Potassium-Exchanging ATPase | 1992 |
Effect of inhibition of Na, K-ATPase on cytosolic free sodium and calcium in platelets of spontaneously hypertensive rats.
Topics: Animals; Blood Platelets; Calcium; Cytosol; Fura-2; Hypertension; Osmolar Concentration; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium-Potassium-Exchanging ATPase; Thrombin | 1992 |
Maximum binding of ouabain to erythrocytes in relation to a family history of essential hypertension, sodium balance and body weight in normotensive children.
Topics: Adolescent; Age Factors; Blood Pressure; Body Mass Index; Child; Erythrocytes; Family Health; Humans; Hypertension; Kidney Diseases; Ouabain; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary | 1992 |
Association of red blood cell sodium leak with blood pressure in recombinant inbred strains.
Topics: Analysis of Variance; Animals; Biological Transport; Blood Pressure; Bumetanide; Erythrocytes; Furosemide; Genetic Markers; Hybridization, Genetic; Hypertension; Male; Ouabain; Potassium; Rats; Rats, Inbred BN; Rats, Inbred SHR; Rubidium; Sodium | 1992 |
Ouabain as an amplifier of mineralocorticoid-induced hypertension.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Desoxycorticosterone; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Hypertension; Kidney; Male; Myocardium; Organ Size; Ouabain; Rats; Rats, Sprague-Dawley; Renin; Sodium Chloride | 1992 |
Red cell sodium in DOCA-salt hypertension: a Brattleboro study.
Topics: Animals; Biological Transport, Active; Blood Pressure; Bumetanide; Desoxycorticosterone; Erythrocytes; Female; Furosemide; Hematocrit; Hemoglobins; Hypertension; In Vitro Techniques; Kinetics; Nephrectomy; Ouabain; Rats; Rats, Brattleboro; Rubidium; Sodium; Sodium, Dietary | 1992 |
Elevated endogenous digitalis-like substance in hypertensive diabetic patients with a family history of hypertension.
Topics: Aged; Albuminuria; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Digitalis; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Plants, Medicinal; Plants, Toxic; Sodium-Potassium-Exchanging ATPase | 1991 |
Erythrocyte membrane ouabain-sensitive Na+, K(+)-ATPase of hypertensive Nigerians.
Topics: Biological Transport, Active; Erythrocyte Membrane; Humans; Hypertension; Magnesium; Nigeria; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase | 1991 |
Increased Na pump activity in the kidney cortex of the Milan hypertensive rat strain.
Topics: Animals; Cell Membrane; Hypertension; In Vitro Techniques; Kidney Cortex; Kinetics; Ouabain; Potassium; Rats; Rats, Mutant Strains; Sodium; Sodium Dodecyl Sulfate; Sodium-Potassium-Exchanging ATPase | 1991 |
Influence of family history of cryptogenic hypertension, age, sex and race on lymphocyte sodium/potassium pumps.
Topics: Adult; Age Factors; Asian People; Female; Humans; Hypertension; India; Lymphocytes; Male; Middle Aged; Ouabain; Rubidium Radioisotopes; Sex Factors; Sodium-Potassium-Exchanging ATPase; White People | 1991 |
A greater stimulation of Na-H antiport in cultured vascular smooth muscle cells by serum from spontaneously hypertensive rats.
Topics: Amiloride; Animals; Blood Pressure; Carrier Proteins; Cells, Cultured; Hypertension; Male; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rubidium; Sodium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1991 |
Effects of ouabain on membrane fluidity of erythrocytes in essential hypertension. An electron spin resonance study.
Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Erythrocytes; Humans; Hypertension; Membrane Fluidity; Middle Aged; Ouabain; Sodium-Potassium-Exchanging ATPase | 1991 |
[Endogenous ouabain--key to the genesis of hypertension?].
Topics: Animals; Blood Pressure; Cardenolides; Digoxin; Humans; Hypertension; Ouabain; Plasma Volume; Saponins; Sodium-Potassium-Exchanging ATPase | 1991 |
Vascular sodium pump activity kinetics in early and advanced stages of deoxycorticosterone-salt hypertension in rats.
Topics: Animals; Arteries; Body Weight; Desoxycorticosterone; Hypertension; Kinetics; Male; Ouabain; Potassium; Rats; Rats, Inbred Strains; Rubidium; Sodium; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 1991 |
Altered responses of aortic smooth muscle from Sprague-Dawley rats with salt-induced hypertension.
Topics: Animals; Aorta, Thoracic; Calcium Chloride; Hypertension; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Potassium; Rats; Rats, Inbred Strains; Serotonin; Sodium; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 1991 |
Ouabain-like Na+,K(+)-ATPase inhibitory activity of a plasma extract in normal pregnancy and pregnancy induced hypertension.
Topics: Adult; Blood Pressure; Ca(2+) Mg(2+)-ATPase; Digoxin; Erythrocyte Membrane; Female; Humans; Hypertension; Ouabain; Pregnancy; Pregnancy Complications, Cardiovascular; Sodium-Potassium-Exchanging ATPase; Vanadates | 1991 |
[Various properties of the Na+, K(+)-ATPase and the Mg (2+)-ATPase in erythrocytes from normotensive and hypertensive subjects].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Aged; Ca(2+) Mg(2+)-ATPase; Erythrocyte Membrane; Humans; Hypertension; Middle Aged; Ouabain; Sodium-Potassium-Exchanging ATPase | 1991 |
Effects of ouabain and verapamil on endothelin-1-induced contraction of mesenteric artery in young spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Endothelins; Heart Rate; Hypertension; In Vitro Techniques; Isometric Contraction; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction; Verapamil | 1991 |
Brain ouabain and central effects of dietary sodium in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Diet; Guanabenz; Heart Rate; Hypertension; Injections, Intraventricular; Kidney; Male; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rest; Sodium; Stress, Psychological; Sympathetic Nervous System | 1992 |
86Rb and 22Na transport in primary cultured renal cells from spontaneously hypertensive rats.
Topics: Amiloride; Animals; Biological Transport; Carrier Proteins; Cells, Cultured; Furosemide; Hypertension; Kidney; Male; Ouabain; Potassium Radioisotopes; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rubidium; Sodium; Sodium-Potassium-Chloride Symporters | 1991 |
Platelet-free calcium and vascular calcium uptake in ethanol-induced hypertensive rats.
Topics: Administration, Oral; Aldosterone; Animals; Aorta; Blood Platelets; Blood Pressure; Body Weight; Calcium; Creatinine; Drinking; Eating; Ethanol; Hypertension; Magnesium; Male; Ouabain; Potassium; Rats; Rats, Inbred WKY; Renin; Rubidium; Sodium; Systole | 1991 |
Genetic traits related to hypertension and electrolyte metabolism.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiporters; Binding Sites; Carrier Proteins; Child; Child, Preschool; Electrolytes; Genes, Recessive; Humans; Hypertension; Kallikreins; Middle Aged; Ouabain; Pedigree; Skinfold Thickness | 1991 |
Ion transport in erythrocytes of Prague hypertensive rat.
Topics: Animals; Biological Transport; Erythrocytes; Furosemide; Hypertension; Kinetics; Male; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sodium | 1990 |
Erythrocyte sodium transport and renal sodium excretion after saline loading in young and adult spontaneously hypertensive (SHR) and normotensive (WKY) rats.
Topics: Animals; Blood Pressure; Erythrocytes; Hypertension; Kidney; Male; Natriuresis; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium | 1990 |
Race, sex, and family history of hypertension and erythrocyte sodium pump [3H]ouabain binding.
Topics: Adolescent; Black People; Child; Erythrocytes; Female; Humans; Hypertension; Male; Ouabain; Sex Factors; Sodium; Sodium-Potassium-Exchanging ATPase; White People | 1990 |
Plasma digitalis-like activity and cytosolic Ca2+ in essential hypertension.
Topics: Adolescent; Adult; Aged; Blood Platelets; Blood Proteins; Calcium; Cardenolides; Cytosol; Digoxin; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase | 1990 |
The role of Na,K-ATPase inhibitor on pressor responsiveness in patients with benign essential hypertension.
Topics: Adult; Blood Pressure; Calcium; Female; Heart Rate; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Norepinephrine; Ouabain; Pressoreceptors; Sodium-Potassium-Exchanging ATPase | 1990 |
Effects of canrenone on blood pressure in rats with reduced renal mass.
Topics: Animals; Biological Transport, Active; Blood Pressure; Canrenone; Hypertension; Injections, Intramuscular; Male; Myocardium; Nephrectomy; Ouabain; Potassium; Pregnadienes; Rats; Rats, Inbred Strains; Renin; Sodium; Sodium-Potassium-Exchanging ATPase | 1990 |
Purification of a Na+/K+ ATPase inhibitor from borderline hypertensives' plasma.
Topics: Chromatography, High Pressure Liquid; Erythrocytes; Humans; Hypertension; Kinetics; Ouabain; Protein Binding; Rubidium; Sodium-Potassium-Exchanging ATPase; Ultrafiltration | 1990 |
Modulatory effect of some steroid hormones, their glucuronides and ouabain-like compounds on Cavia cobaya kidney Na+,K(+)-ATPase activity.
Topics: Animals; Binding, Competitive; Dose-Response Relationship, Drug; Glucuronates; Guinea Pigs; Hormones; Hypertension; In Vitro Techniques; Kidney; Ligands; Ouabain; Proteins; Sodium-Potassium-Exchanging ATPase; Steroids | 1990 |
Calcium uptake kinetics into brush-border membrane vesicles: higher Vmax in the spontaneously hypertensive rat than in normotensive control.
Topics: Animals; Calcium; Duodenum; Homeostasis; Hypertension; Intestinal Absorption; Intestinal Mucosa; Kinetics; Male; Microvilli; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1990 |
Digitalis-like activity in human plasma: relation to blood pressure and sodium balance.
Topics: Adolescent; Adult; Aged; Animals; Blood Pressure; Cells, Cultured; Digitalis Glycosides; Dogs; Female; Humans; Hypertension; In Vitro Techniques; Kidney Tubules; Male; Middle Aged; Ouabain; Sodium; Sodium, Dietary; Tritium | 1990 |
Effect of gender in centrally induced angiotensin II hypertension in dogs.
Topics: Angiotensin II; Animals; Arteries; Brain; Dogs; Female; Hemodynamics; Hypertension; Injections, Intraventricular; Male; Ouabain; Rubidium; Sex Characteristics; Tail | 1990 |
Sodium content and sodium efflux of mononuclear leucocytes from young subjects at increased risk of developing essential hypertension.
Topics: Adolescent; Adult; Analysis of Variance; Biological Transport, Active; Blood Pressure Determination; Humans; Hypertension; Leukocytes, Mononuclear; Male; Ouabain; Potassium; Risk Factors; Sodium | 1990 |
Kinetics of Na+ and K+ transport in red blood cells of Dahl rats. Effects of age and salt.
Topics: Analysis of Variance; Animals; Biological Transport, Active; Blood Pressure; Erythrocytes; Furosemide; Hypertension; Kinetics; Male; Organ Size; Ouabain; Potassium; Rats; Rats, Inbred Strains; Rubidium; Sodium; Sodium, Dietary; Time Factors | 1990 |
Chronic treatment with nifedipine prevents development of hypertension and abnormal red cell Na+ transport in Dahl-S-rats.
Topics: Animals; Bumetanide; Erythrocyte Membrane; Erythrocytes; Female; Hypertension; In Vitro Techniques; Ion Channels; Magnesium; Magnesium Chloride; Nifedipine; Ouabain; Rats; Rats, Inbred Strains; Sodium | 1985 |
Examination of the ouabain-sensitive Na-K pump in essential hypertensive children of normal body weight.
Topics: Adolescent; Blood Pressure; Body Weight; Child; Erythrocyte Membrane; Erythrocytes; Humans; Hypertension; Ion Channels; Ouabain; Potassium; Sodium | 1985 |
Na+-K+ regulation in cultured vascular smooth muscle cell of the spontaneously hypertensive rat.
Topics: Animals; Biological Transport; Calcium; Carotid Arteries; Cells, Cultured; Hypertension; Ion Channels; Kinetics; Male; Muscle, Smooth, Vascular; Ouabain; Potassium; Radioisotopes; Rats; Rats, Inbred Strains; Rats, Inbred WKY; Rubidium; Sodium; Sodium Radioisotopes | 1986 |
Ouabain binding to cultured vascular smooth muscle cells of the spontaneously hypertensive rat.
Topics: Animals; Carotid Arteries; Cell Membrane Permeability; Cells, Cultured; Hypertension; Ion Channels; Male; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Sodium | 1986 |
Reversible inhibition of leucocyte sodium pumps by a circulating serum factor in essential hypertension.
Topics: Adult; Biological Transport, Active; Female; Humans; Hypertension; Ion Channels; Leukocytes; Male; Middle Aged; Ouabain; Radioisotopes; Rubidium; Sodium | 1986 |
A circulating Na+-K+ATPase inhibitor, erythrocyte sodium transport and hypertension in patients with chronic renal failure.
Topics: Adult; Biological Transport, Active; Enzyme Inhibitors; Erythrocytes; Female; Humans; Hypertension; Ion Channels; Male; Middle Aged; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase; Uremia | 1986 |
Increased sodium influx into erythrocytes in diabetes mellitus and hypertension.
Topics: Adult; Biological Transport, Active; Diabetes Complications; Diabetes Mellitus; Erythrocytes; Female; Humans; Hypertension; Ion Channels; Male; Middle Aged; Ouabain; Potassium; Sodium | 1986 |
Prehypertensive changes in sodium transport induced by deoxycorticosterone acetate in incubated rat tail artery.
Topics: Animals; Arteries; Biological Transport; Blood Pressure; Body Water; Desoxycorticosterone; Hypertension; Intracellular Fluid; Ion Channels; Male; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Sodium; Tail | 1986 |
Sodium pump parameters of red blood cells in men, women and women taking oral contraceptives.
Topics: Adult; Binding Sites; Biological Transport; Contraceptives, Oral; Erythrocytes; Female; Humans; Hypertension; Ion Channels; Male; Middle Aged; Ouabain; Sex Characteristics; Sodium | 1986 |
[Compounds of the digoxin type in essential and experimental hypertension].
Topics: Adenosine Triphosphatases; Animals; Antibody Specificity; Blood Proteins; Cardenolides; Digoxin; Erythrocyte Membrane; Female; Humans; Hypertension; Ion Channels; Kidney; Male; Ouabain; Rats; Rats, Inbred Strains; Saponins | 1986 |
Reduced sodium concentration and increased sodium-potassium pump activity of erythrocytes in human hypertension.
Topics: Binding Sites; Erythrocytes; Humans; Hypertension; Ion Channels; Male; Osmolar Concentration; Ouabain; Potassium; Radioisotopes; Reference Values; Rubidium; Sodium | 1987 |
Sodium pump inhibitor in the serum of patients with essential hypertension and its partial purification from hemofiltrate.
Topics: Animals; Blood; Blood Pressure; Brain; Cattle; Digitalis; Humans; Hypertension; Ion Channels; Ouabain; Plants, Medicinal; Plants, Toxic; Sodium; Ultrafiltration | 1987 |
Augmented vascular responses to ouabain in SHRSP during salt loading.
Topics: Animals; Blood Pressure; Blood Vessels; Diet; Hindlimb; Hypertension; Ion Channels; Male; Nitroprusside; Norepinephrine; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcolemma; Sodium; Vascular Resistance; Vasoconstriction | 1987 |
Sodium transport parameters in erythrocytes of patients with primary aldosteronism.
Topics: Adult; Erythrocytes; Female; Humans; Hyperaldosteronism; Hypertension; Ion Channels; Male; Middle Aged; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase | 1988 |
Abnormal erythrocyte sodium leak in a subset of essential hypertensive patients.
Topics: Adult; Aged; Biological Transport; Bumetanide; Erythrocytes; Female; Humans; Hypertension; Ion Channels; Male; Middle Aged; Ouabain; Potassium; Sodium | 1989 |
Acute sodium loading alters sodium pump in Caucasian hypertensive subjects.
Topics: Adult; Biological Transport; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase | 1989 |
Erythrocyte sodium and sodium flux in relation to hypertension in chronic renal failure.
Topics: Adult; Cells, Cultured; Erythrocyte Aging; Erythrocytes; Female; Furosemide; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Ouabain; Potassium; Sodium; Sodium Channels | 1989 |
Digoxin-like immunoreactivity, displacement of ouabain and inhibition of Na+/K+ ATPase by four steroids known to be increased in essential hypertension.
Topics: Animals; Blood Proteins; Cardenolides; Digoxin; Dogs; Hypertension; Immune Sera; In Vitro Techniques; Kidney; Ouabain; Saponins; Sodium-Potassium-Exchanging ATPase; Steroids | 1989 |
Increased number of ouabain binding sites in lymphocytes from borderline hypertensives.
Topics: Adolescent; Adult; Blood Pressure Determination; Humans; Hypertension; Lymphocytes; Male; Ouabain; Potassium Channels; Receptors, Drug; Sodium Channels; Sodium-Potassium-Exchanging ATPase | 1989 |
Regulation of Na+ and K+ contents in rat thymocytes.
Topics: Animals; Biological Transport; Blood Coagulation Factors; Bumetanide; Dinoprostone; Hypertension; Isoproterenol; Kinetics; Male; Ouabain; Platelet Activating Factor; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Sodium; Sodium Channels; T-Lymphocytes | 1989 |
Facilitatory effects of ouabain and digitalis-like substance on adrenergic transmission in hypertension.
Topics: Animals; Blood Pressure; Digitalis; Hypertension; Male; Nephrectomy; Norepinephrine; Ouabain; Plants, Medicinal; Plants, Toxic; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sodium Chloride; Splanchnic Circulation; Sympathetic Nervous System; Synaptic Transmission | 1989 |
Na,K-ATPase activity in renal tubule cells from Milan hypertensive rats.
Topics: Amphotericin B; Animals; Hypertension; In Vitro Techniques; Kidney Tubules; Loop of Henle; Male; Ouabain; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1989 |
Increased furosemide-sensitive sodium influx into erythrocytes in non-insulin-dependent diabetes mellitus associated with hypertension.
Topics: Adolescent; Adult; Aged; Diabetes Mellitus, Type 2; Erythrocytes; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Ouabain; Potassium; Rubidium Radioisotopes; Sodium; Sodium Channels | 1989 |
Comparison between endogenous digoxin-like immunoreactivity and 86Rb uptake by erythrocytes in extracts of human plasma.
Topics: Adult; Blood Proteins; Cardenolides; Digoxin; Erythrocytes; Humans; Hypertension; Infant, Newborn; Ouabain; Rubidium Radioisotopes; Saponins; Sodium Channels; Sodium-Potassium-Exchanging ATPase | 1989 |
Plasma ouabain-like activity in essential hypertensive patients and in subjects with primary aldosteronism.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cardenolides; Digoxin; Female; Glomerular Filtration Rate; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Ouabain; Protein Binding; Renin; Saponins; Sodium-Potassium-Exchanging ATPase | 1989 |
[Therapeutic response to canrenone of patients with essential hypertension as a function of sodium transport anomalies and ouabain sensitivity of erythrocytes].
Topics: Biological Transport; Canrenone; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Pregnadienes; Sodium Channels; Time Factors | 1989 |
Studies on the role of sodium- and potassium-activated adenosine triphosphatase inhibition in the pathogenesis of human hypertension. Changes in vascular and cardiac function following inhibition of the sodium pump in normotensive subjects and effects of
Topics: Adenosine Triphosphate; Adult; Blood Pressure; Calcium; Erythrocytes; Hemodynamics; Humans; Hypertension; Ion Channels; Male; Nifedipine; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase; Vasoconstriction; Water-Electrolyte Balance | 1985 |
Chemical, experimental, and clinical studies on endogenous ouabain-like substance in hypertension.
Topics: Adult; Aged; Animals; Blood Platelets; Blood Pressure; Female; Humans; Hypertension; Ion Channels; Kidney; Male; Middle Aged; Ouabain; Potassium; Rats; Rats, Inbred Strains; Serotonin; Sodium; Sodium-Potassium-Exchanging ATPase | 1985 |
Norepinephrine-induced phasic activity in tail arteries from genetically hypertensive rats.
Topics: Animals; Arteries; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Hypertension; Ion Channels; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tail; Tetraethylammonium; Tetraethylammonium Compounds | 1985 |
Leucocyte sodium content and sodium pump activity in overweight and lean hypertensives.
Topics: Biological Transport; Female; Humans; Hypertension; Leukocytes; Male; Middle Aged; Obesity; Ouabain; Sodium | 1989 |
Erythrocyte Na+, K+ pump inhibition after saline infusion in essentially hypertensive subjects: effects of canrenone administration.
Topics: Adult; Biological Transport, Active; Blood Pressure; Canrenone; Erythrocytes; Extracellular Space; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Potassium; Pregnadienes; Sodium; Sodium Chloride | 1989 |
Erythrocyte sodium transport and blood pressure in white subjects.
Topics: Adult; Binding Sites; Blood Pressure; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Reference Values; Renin; Sodium; White People | 1989 |
Platelet intracellular free Ca2+ after incubation with plasma from hypertensive patients.
Topics: Adult; Aminoquinolines; Blood Platelets; Calcium; Female; Humans; Hypertension; Male; Middle Aged; Ouabain | 1989 |
Increased 22Na+-influx in lymphocytes from offspring of essential hypertensive patients.
Topics: Adolescent; Adult; Humans; Hypertension; Lymphocytes; Male; Ouabain; Risk Factors; Sodium; Sodium Chloride | 1989 |
Centrally induced vasopressor responses to ouabain in DOCA-salt hypertensive rats.
Topics: Action Potentials; Animals; Blood Pressure; Desoxycorticosterone; Heart Rate; Hypertension; Hypothalamus; Injections, Intraventricular; Ouabain; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Sympathetic Nervous System | 1987 |
[Genetic hypertension in the SHR rat and circulating digitalis compounds].
Topics: Animals; Binding, Competitive; Cross Reactions; Digitalis Glycosides; Erythrocytes; Hypertension; Male; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Sodium; Sodium-Potassium-Exchanging ATPase | 1987 |
Effect of treatment with hydrochlorothiazide on the red cell Na,K-adenosine triphosphatase in men with hypertension.
Topics: Adult; Erythrocytes; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ouabain; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase | 1987 |
Ouabainlike Na+,K+-ATPase inhibitor in the plasma of normotensive and hypertensive humans and rats.
Topics: Animals; Enzyme Activation; Glucosephosphate Dehydrogenase; Guinea Pigs; Histocytochemistry; Humans; Hypertension; Hypothalamus; Kidney Tubules, Proximal; Ouabain; Peptides; Plasma Volume; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary | 1987 |
Humoral sodium transport inhibitor in acute volume expansion and low renin hypertension.
Topics: Animals; Biological Transport, Active; Blood Volume; Dogs; Hot Temperature; Hypertension; Hypertension, Renovascular; Membrane Potentials; Ouabain; Peptides; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Renin; Rubidium; Sodium; Sodium-Potassium-Exchanging ATPase; Uremia | 1987 |
An endogenous digitalis-like compound extracted from human urine: biochemical and chemical studies.
Topics: Adult; Animals; Blood Proteins; Cardenolides; Chromatography, High Pressure Liquid; Digoxin; Erythrocytes; Female; Humans; Hypertension; Kidney; Kinetics; Male; Natriuresis; Ouabain; Rats; Rats, Inbred Strains; Reference Values; Saponins; Serotonin; Sodium-Potassium-Exchanging ATPase | 1987 |
Evidence for a digitalis-like substance in the hypothalamopituitary axis in rats: implications in the central cardiovascular regulation associated with an excess intake of sodium.
Topics: Animals; Blood Pressure; Blood Proteins; Cardenolides; Cardiovascular System; Desoxycorticosterone; Digoxin; Heart Rate; Hypertension; Hypothalamo-Hypophyseal System; Immunohistochemistry; Injections, Intraventricular; Male; Ouabain; Pituitary-Adrenal System; Radioimmunoassay; Rats; Rats, Inbred Strains; Saponins; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary | 1987 |
Effects of ouabain on adrenergic neurotransmission in spontaneously hypertensive rats.
Topics: Animals; Electric Stimulation; Hypertension; Male; Nerve Endings; Norepinephrine; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase; Sympathetic Nervous System; Synaptic Transmission | 1988 |
(Na+ -K+)ATPase activity in erythrocyte membranes of spontaneously, one kidney-one wrapped, and deoxycorticosterone acetate--NaCl hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Electrolytes; Erythrocyte Membrane; Hematocrit; Hypertension; Ouabain; Rats; Rats, Inbred SHR; Sodium-Potassium-Exchanging ATPase | 1988 |
Increase in plasma ouabainlike inhibitor of Na+, K+-ATPase with high sodium intake in patients with essential hypertension.
Topics: Blood Pressure; Blood Volume; Female; Humans; Hypertension; Male; Middle Aged; Natriuresis; Ouabain; Renin; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary | 1987 |
Hypertensive dog plasma inhibits the Na+-K+ pump of cultured vascular smooth muscle.
Topics: Animals; Dogs; Hypertension; Membranes; Muscle, Smooth, Vascular; Ouabain; Rubidium; Sodium-Potassium-Exchanging ATPase | 1988 |
Effects of saline infusion and canrenone on erythrocyte Na+,K+ pump activity.
Topics: Adult; Canrenone; Erythrocytes; Female; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; Ouabain; Pregnadienes; Sodium; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 1988 |
Species sensitivity of the sodium pump to a circulating ouabain-like inhibitor in acute hypervolemia and DOCA hypertension: comparison with ouabain.
Topics: Animals; Blood Volume; Desoxycorticosterone; Humans; Hypertension; Ouabain; Rats; Sheep; Sodium Channels; Species Specificity; Swine | 1988 |
Individual variability in membrane sodium transport during salt loading--evidence against the production of a Na+-K+-ATPase inhibitor in hypertension.
Topics: Adult; Binding Sites; Biological Transport, Active; Erythrocyte Membrane; Humans; Hypertension; Male; Middle Aged; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary | 1988 |
[Ex vivo and in vitro effects of trandolapril on the efflux of 22Na from the caudal artery of the SHR rat. Inhibition of vascular angiotensin II production].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Cell Membrane; Enalapril; Hypertension; Indoles; Male; Ouabain; Rats; Rats, Inbred SHR; Saralasin; Sodium; Sodium Radioisotopes; Tail | 1988 |
Effects of lead and natriuretic hormone on kinetics of sodium-potassium-activated adenosine triphosphatase: possible relevance to hypertension.
Topics: Animals; Cerebral Cortex; Hypertension; In Vitro Techniques; Lead; Natriuretic Agents; Ouabain; Sodium-Potassium-Exchanging ATPase; Swine | 1988 |
A plasma inhibitor of sodium and potassium activated adenosine triphosphatase in patients with essential hypertension.
Topics: Adult; Blood Pressure; Female; Humans; Hypertension; Kinetics; Male; Ouabain; Reference Values; Sodium-Potassium-Exchanging ATPase | 1988 |
Platelet 5-HT content and uptake in essential hypertension: role of endogenous digitalis-like factors and plasma cholesterol.
Topics: Adult; Blood Platelets; Blood Proteins; Cardenolides; Cholesterol; Digoxin; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Saponins; Serotonin; Sodium-Potassium-Exchanging ATPase | 1988 |
The effect of ouabain on pressor responses to infused noradrenaline in patients with essential hypertension.
Topics: Blood Pressure; Humans; Hypertension; Norepinephrine; Ouabain; Renin; Sodium-Potassium-Exchanging ATPase | 1988 |
Sodium transport in erythrocytes: differences between normal children and children with primary and secondary hypertension.
Topics: Adolescent; Biological Transport, Active; Child; Child, Preschool; Erythrocytes; Humans; Hypertension; Hypertension, Renal; Ouabain; Sodium | 1989 |
Affinity chromatography for human Na+, K+-ATPase inhibitors in plasma and urine.
Topics: Animals; Binding, Competitive; Chromatography, Affinity; Chromatography, High Pressure Liquid; Cross Reactions; Digoxin; Dogs; Enzymes, Immobilized; Humans; Hydrolysis; Hypertension; In Vitro Techniques; Kidney; Ouabain; Receptors, Drug; Sodium-Potassium-Exchanging ATPase | 1985 |
In ability of Na+,K+-ATPase inhibitor to cause hypertension in sodium-loaded or deoxycorticosterone-treated one kidney rats.
Topics: Animals; Atropine; Blood Pressure; Desoxycorticosterone; Digitoxin; Enzyme Inhibitors; Hypertension; Kidney; Male; Ouabain; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Sodium; Sodium-Potassium-Exchanging ATPase; Time Factors | 1985 |
[Transmembrane potential and electrogenicity of thrombocyte Na, K-ATPase in different forms of hypertension in rats].
Topics: Animals; Blood Platelets; Desoxycorticosterone; Hypertension; Hypertension, Renal; Male; Membrane Potentials; Ouabain; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence | 1985 |
Evidence for a Na-K-ATPase-inhibitor in erythrocytes of patients with essential hypertension.
Topics: Adolescent; Adult; Cell Separation; Dialysis; Erythrocyte Membrane; Erythrocytes; Hemolysis; Humans; Hypertension; In Vitro Techniques; Male; Middle Aged; Ouabain; Sodium-Potassium-Exchanging ATPase | 1985 |
Dehydroepiandrosterone sulfate as a digitalis like factor in plasma of healthy human adults.
Topics: Adult; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Digitalis; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Plants, Medicinal; Plants, Toxic; Sodium-Potassium-Exchanging ATPase | 1985 |
Sensitive assay and kinetic property of urinary inhibitor of Na+, K+-ATPase in sodium-loaded patients with essential hypertension.
Topics: Binding Sites; Cell Membrane; Humans; Hypertension; Kinetics; Ouabain; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 1985 |
Abnormal relationship between dietary sodium intake and red cell sodium transport in salt-sensitive patients with essential hypertension.
Topics: Adult; Aged; Biological Transport, Active; Diet, Sodium-Restricted; Drug Resistance; Erythrocyte Membrane; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase | 1985 |
Circulating factor with ouabain-like immunoreactivity in patients with primary aldosteronism.
Topics: Antibody Affinity; Humans; Hyperaldosteronism; Hypertension; Ouabain; Sodium-Potassium-Exchanging ATPase | 1986 |
Na-K-adenosine triphosphatase and cation content in the erythrocyte in essential hypertension.
Topics: Blood Pressure; Erythrocytes; Humans; Hypertension; Ouabain; Potassium; Reference Values; Sodium; Sodium-Potassium-Exchanging ATPase | 1986 |
Na+-K+-ATPase in vascular smooth muscle.
Topics: Alkaline Phosphatase; Animals; Aorta; Dogs; Female; Hypertension; Magnesium; Male; Muscle, Smooth, Vascular; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase; Time Factors | 1986 |
Blood pressure in essential hypertension correlates with the concentration of a circulating inhibitor of the sodium pump.
Topics: Adult; Aged; Female; Humans; Hypertension; Lymphocytes; Male; Middle Aged; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase | 1986 |
Intracellular sodium concentration and transport in red cells in essential hypertension, hyperthyroidism, pregnancy and hypokalemia.
Topics: Adult; Biological Transport; Erythrocytes; Female; Humans; Hypertension; Hyperthyroidism; Hypokalemia; Lithium; Male; Ouabain; Pregnancy; Sodium; Sodium-Potassium-Exchanging ATPase | 1986 |
Lymphocyte sodium efflux in normotensive and borderline hypertensive subjects with and without heredity for hypertension.
Topics: Biological Transport, Active; Furosemide; Humans; Hypertension; Lymphocytes; Ouabain; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase | 1986 |
Vascular effects of altered sodium, potassium pump activity.
Topics: Animals; Humans; Hypertension; Muscle Tonus; Muscle, Smooth, Vascular; Ouabain; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase; Vascular Resistance; Vasomotor System | 1986 |
Plasma digitalislike activity in essential hypertension or end-stage renal disease.
Topics: Adult; Aged; Blood Pressure; Digitalis Glycosides; Erythrocytes; Female; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Ouabain; Renal Dialysis; Sodium; Sodium-Potassium-Exchanging ATPase | 1986 |
Excretion of artifactual endogenous digitalis-like factors.
Topics: Animals; Chromatography, Affinity; Desoxycorticosterone; Digoxin; Erythrocyte Membrane; False Positive Reactions; Hypertension; Male; Ouabain; Rats; Rats, Inbred Strains; Rubidium; Sodium-Potassium-Exchanging ATPase | 1986 |
Vascular responses to ouabain and norepinephrine in low and normal renin hypertension.
Topics: Adult; Female; Forearm; Humans; Hypertension; Male; Norepinephrine; Ouabain; Regional Blood Flow; Renin; Sodium-Potassium-Exchanging ATPase; Vascular Resistance | 1986 |
Recent progress on an endogenous digitalislike factor in hypertension.
Topics: Adult; Binding, Competitive; Blood Proteins; Cardenolides; Digoxin; Dose-Response Relationship, Drug; Erythrocytes; Female; Homeostasis; Humans; Hypertension; Male; Middle Aged; Ouabain; Saponins; Sodium; Sodium-Potassium-Exchanging ATPase | 1986 |
Direct demonstration of an inhibitor of sodium, potassium dependent adenosine triphosphatase (Na+, K+-ATPase) in plasma from normotensive and hypertensive subjects.
Topics: Humans; Hypertension; Kinetics; Lithium; Methanol; Ouabain; Reference Values; Sodium-Potassium-Exchanging ATPase | 1986 |
Effects of ouabain on blood pressure regulation in rats.
Topics: Animals; Blood Pressure; Hypertension; Male; Norepinephrine; Ouabain; Rats; Rats, Inbred Strains; Sodium; Sodium-Potassium-Exchanging ATPase | 1986 |
Kinetic study of Na+-K+ pump in erythrocytes from essential hypertensive patients.
Topics: Erythrocytes; Humans; Hypertension; Kinetics; Models, Biological; Ouabain; Reference Values; Sodium; Sodium-Potassium-Exchanging ATPase | 1987 |
A quantitative receptor assay for "digitalis-like" compounds in serum. Demonstration of raised concentrations in essential hypertension and correlation with arterial blood pressure.
Topics: Adolescent; Adult; Binding, Competitive; Blood Pressure; Blood Proteins; Cardenolides; Digoxin; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Ouabain; Radioligand Assay; Receptors, Drug; Saponins; Sodium-Potassium-Exchanging ATPase | 1987 |
Red blood cell Na+,K+-ATPase in men with newly diagnosed or previously treated essential hypertension.
Topics: Adult; Antihypertensive Agents; Biological Transport, Active; Blood Pressure; Erythrocytes; Humans; Hypertension; Male; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase | 1987 |
Measurement by bioluminescence technique of erythrocyte membrane Na+,K+-ATPase activity in hypertensive patients.
Topics: Adult; Erythrocyte Membrane; Female; Humans; Hypertension; Hypertension, Renovascular; Isoquinolines; Luminescent Measurements; Male; Middle Aged; Ouabain; Sodium-Potassium-Exchanging ATPase | 1987 |
Endogenous Na+ transport inhibitor in human hypertension: further biochemical and chemical studies.
Topics: Animals; Blood Platelets; Cardenolides; Chemical Phenomena; Chemistry; Digoxin; Dogs; Humans; Hypertension; Osmolar Concentration; Ouabain; Peptides; Potassium; Rats; Saponins; Serotonin; Sodium; Sodium-Potassium-Exchanging ATPase | 1987 |
Ouabain-like and non-ouabain-like factors in plasma of patients with essential hypertension.
Topics: Adult; ATPase Inhibitory Protein; Blood Proteins; Humans; Hypertension; Immunoassay; Middle Aged; Ouabain; Proteins; Sodium-Potassium-Exchanging ATPase | 1987 |
[Canrenone: an effective antihypertensive in an experimental model of hypertension in which the active transport of sodium is diminished].
Topics: Animals; Antihypertensive Agents; Canrenone; Cell Membrane Permeability; Creatinine; Diuresis; Hypertension; Male; Natriuresis; Ouabain; Pregnadienes; Rats; Renin; Sodium; Urea | 1986 |
Influence of race, sex, and blood pressure on erythrocyte sodium transport in humans.
Topics: Adult; Aged; Antiporters; Biological Transport; Black People; Blood Pressure; Carrier Proteins; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Reference Values; Sex Characteristics; Sodium; White People | 1988 |
Ouabain-induced contraction of vascular smooth muscle in spontaneously hypertensive rats and the effect of hydralazine.
Topics: Aging; Animals; Blood Pressure; Body Weight; Calcium; Calcium Radioisotopes; Hydralazine; Hypertension; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Phentolamine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1988 |
Spontaneous vasomotion in pressurized cerebral arteries from genetically hypertensive rats.
Topics: Animals; Cerebral Arteries; Chlorides; Hypertension; Indomethacin; Manganese; Manganese Compounds; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Vascular Resistance; Vasomotor System | 1988 |
A higher cellular sodium turnover rate in cultured skin fibroblasts from blacks.
Topics: Adult; Black People; Cells, Cultured; Female; Fibroblasts; Humans; Hypertension; Male; Ouabain; Sodium | 1988 |
A digoxin-like factor associates with erythrocyte sodium concentration, sodium transport, and ouabain binding.
Topics: Adult; Aging; Blood Pressure; Blood Proteins; Body Weight; Cardenolides; Child; Digoxin; Erythrocytes; Female; Humans; Hypertension; Male; Ouabain; Protein Binding; Radioimmunoassay; Saponins; Sodium | 1988 |
Area postrema ablation and vascular reactivity in deoxycorticosterone-salt-treated rats.
Topics: Animals; Arteries; Blood Pressure; Desoxycorticosterone; Drug Synergism; Hypertension; Isometric Contraction; Male; Medulla Oblongata; Muscle, Smooth, Vascular; Ouabain; Potassium Chloride; Rats; Rats, Inbred Strains; Serotonin; Sodium Chloride; Vasoconstriction | 1988 |
Relationship between red cell sodium transport, blood pressure, and family history of hypertension.
Topics: Biological Transport; Blood Pressure; Erythrocytes; Furosemide; Humans; Hypertension; Ion Exchange; Medical Records; Middle Aged; Ouabain; Reference Values; Sodium | 1988 |
Effects of oral magnesium on blood pressure and red cell sodium transport in patients receiving long-term thiazide diuretics for hypertension.
Topics: Administration, Oral; Benzothiadiazines; Biological Transport; Blood Pressure; Diuretics; Erythrocytes; Female; Humans; Hypertension; Magnesium; Male; Middle Aged; Ouabain; Sodium; Sodium Chloride Symporter Inhibitors | 1988 |
Sodium and noradrenaline effluxes from platelets in male relatives to hypertensive individuals.
Topics: Adult; Binding Sites; Blood Platelets; Humans; Hypertension; Kinetics; Male; Middle Aged; Norepinephrine; Ouabain; Sodium | 1987 |
Vasoconstrictor effects of endogenous digitalis-like factors extracted from urine of hypertensive patients.
Topics: Animals; Arteries; Blood Proteins; Cardenolides; Digoxin; Dogs; Ear, External; Epinephrine; Humans; Hypertension; In Vitro Techniques; Mesenteric Arteries; Ouabain; Phentolamine; Potassium Chloride; Quinazolines; Saponins; Vasoconstrictor Agents; Verapamil | 1987 |
The 3H-ouabain binding capacity of skeletal muscle from spontaneously hypertensive rats shows marginal changes in comparison to the major effects of differentiation, K-depletion and thyroid status.
Topics: Age Factors; Animals; Catecholamines; Cell Differentiation; Humans; Hypertension; Hyperthyroidism; Hypothyroidism; Insulin; Mice; Muscles; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Drug; Sodium-Potassium-Exchanging ATPase; Thyroid Gland | 1986 |
Reduced serotonin content and uptake in platelets from patients with essential hypertension: is a ouabain-like factor involved?
Topics: Adult; Blood Platelets; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Ouabain; Reference Values; Serotonin | 1987 |
Plasma inhibitors of Na,K-ATPase: relation to salt balance and hypertension.
Topics: Animals; ATPase Inhibitory Protein; Blood Proteins; Blood Volume; Cerebral Hemorrhage; Hypertension; Kidney; Lysophosphatidylcholines; Ouabain; Proteins; Rabbits; Radioligand Assay; Rats; Sodium; Sodium Chloride; Water-Electrolyte Balance | 1987 |
High resolution 23Na-nuclear magnetic resonance study of stroke-prone spontaneously hypertensive rat erythrocytes.
Topics: Animals; Energy Metabolism; Erythrocytes; Hematocrit; Hemolysis; Hypertension; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Osmosis; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium | 1987 |
Effect of DOCA-salt treatment duration and anteroventral third ventricle lesions on a plasma-borne sodium pump inhibitor in rats.
Topics: Animals; ATPase Inhibitory Protein; Biological Transport, Active; Blood Proteins; Cerebral Ventricles; Desoxycorticosterone; Hypertension; In Vitro Techniques; Male; Ouabain; Potassium; Proteins; Rats; Rats, Inbred Strains; Rubidium Radioisotopes; Sodium Chloride | 1987 |
Bumetanide-sensitive sodium-22 transport in vascular smooth muscle cell of the spontaneously hypertensive rat.
Topics: Animals; Biological Transport, Active; Bumetanide; Calcium; Diuretics; Erythrocytes; Hypertension; Kinetics; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Sodium; Sodium Radioisotopes | 1986 |
Evidence for increased levels of a circulating ouabainlike factor in essential hypertension.
Topics: Adult; Aged; Diastole; Erythrocytes; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Ouabain; Potassium; Receptors, Drug; Sodium-Potassium-Exchanging ATPase; Systole | 1986 |
23Na-NMR studies of Na+ interaction with human red cell membranes from normotensives and hypertensives.
Topics: Adolescent; Adult; Erythrocyte Membrane; Female; Humans; Hypertension; Kinetics; Magnetic Resonance Spectroscopy; Male; Middle Aged; Ouabain; Reference Values; Sodium | 1986 |
Effect of serum from patients with essential hypertension on sodium transport in normal leucocytes.
Topics: Biological Transport; Blood Pressure; Humans; Hypertension; Leukocytes; Middle Aged; Ouabain; Sodium | 1986 |
Genetic basis for altered vascular responses to ouabain and potassium-free solution in hypertension.
Topics: Animals; Aorta; Blood Pressure; Crosses, Genetic; Hypertension; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1986 |
Increased basal and thrombin-induced free calcium in platelets of essential hypertensive patients.
Topics: Adult; Angiotensin II; Blood Platelets; Calcium; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Ouabain; Thrombin | 1987 |
Cerebral intraventricular 6-hydroxydopamine prevents vascular changes in the mineralocorticoid hypertensive rat.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Cerebral Ventricles; Desoxycorticosterone; Hydroxydopamines; Hypertension; Muscle, Smooth, Vascular; Ouabain; Oxidopamine; Rats; Rats, Inbred Strains; Vasoconstriction | 1985 |
Alterations in active Na-K transport during mineralocorticoid-salt hypertension in the rat.
Topics: Aldosterone; Animals; Biological Transport, Active; Chlorides; Desoxycorticosterone; Hypertension; Kinetics; Male; Mathematics; Ouabain; Potassium; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride | 1986 |
Contractile responses to ouabain and K+-free solution in aorta from hypertensive rats.
Topics: Amiloride; Animals; Aorta; Dose-Response Relationship, Drug; Hypertension; In Vitro Techniques; Male; Membrane Potentials; Monensin; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sodium | 1986 |
Cation transport functions in vitro in patients with untreated essential hypertension: a comparison of erythrocytes and leucocytes.
Topics: Adult; Aged; Biological Transport; Cardiac Glycosides; Digoxin; Erythrocytes; Female; Humans; Hypertension; In Vitro Techniques; Leukocytes; Male; Middle Aged; Ouabain; Rubidium; Sodium | 1985 |
[The ouabain-sensitive Na-K pump in children with essential hypertension].
Topics: Adolescent; Biological Transport, Active; Child; Female; Humans; Hypertension; Male; Ouabain; Potassium; Sodium | 1985 |
Evaluation of ouabain-insensitive red blood cell cation transport in uremic patients.
Topics: Adult; Aged; Cell Membrane Permeability; Erythrocyte Membrane; Female; Humans; Hypertension; Lithium; Male; Membrane Lipids; Middle Aged; Ouabain; Oxidation-Reduction; Potassium; Renal Dialysis; Sodium; Uremia | 1985 |
Furosemide-sensitive sodium movements in lymphocytes from essential hypertensives.
Topics: Biological Transport; Furosemide; Humans; Hypertension; In Vitro Techniques; Lymphocytes; Ouabain; Sodium | 1985 |
Factors influencing leucocyte sodium transport in hypertension.
Topics: Biological Transport; Humans; Hypertension; Leukocytes; Ouabain; Sodium | 1985 |
Effects of varying salt diets and of ouabain on cardiovascular neuroeffector characteristics and on myogenic resistance vessel activity in SHR and WKY.
Topics: Animals; Diet, Sodium-Restricted; Hypertension; Male; Muscle, Smooth, Vascular; Neuroeffector Junction; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Vascular Resistance | 1985 |
Plasma ouabain-like properties in hypertension and volume expansion.
Topics: Acromegaly; Adult; Blood Volume; Humans; Hypertension; Kidney Failure, Chronic; Middle Aged; Ouabain; Sodium | 1985 |
Cell volume and metabolic dependence of NEM-activated K+-Cl- flux in human red blood cells.
Topics: Adenosine Triphosphate; Biological Transport; Chlorides; Erythrocyte Volume; Erythrocytes; Ethylmaleimide; Humans; Hypertension; In Vitro Techniques; Osmolar Concentration; Ouabain; Potassium; Rubidium | 1985 |
Arguments for the presence of a Na-K ATPase pump inhibitor in the plasma of uremic and essential hypertensive patients.
Topics: Adult; Aged; ATPase Inhibitory Protein; Blood; Blood Proteins; Blood Volume; Humans; Hypertension; Male; Middle Aged; Natriuresis; Ouabain; Posture; Potassium; Proteins; Ultrafiltration; Uremia | 1985 |
Recent advances on endogenous Na+,K+-ATPase inhibitors: clinical investigation and purification.
Topics: Acromegaly; Animals; ATPase Inhibitory Protein; Binding Sites; Brain; Digitalis; Dogs; Dose-Response Relationship, Drug; Erythrocytes; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Kinetics; Ouabain; Plants, Medicinal; Plants, Toxic; Proteins; Swine | 1985 |
Mononuclear leucocyte intracellular free calcium--does it correlate with blood pressure?
Topics: Adult; Aged; Blood Pressure; Calcium; Cytosol; Female; Humans; Hypertension; Leukocytes; Male; Middle Aged; Ouabain | 1985 |
Rubidium and sodium transport across erythrocyte membrane: alterations due to a circulating factor.
Topics: Adult; Biological Transport, Active; Blood Proteins; Dialysis; Erythrocyte Membrane; Female; Humans; Hypertension; In Vitro Techniques; Kinetics; Male; Middle Aged; Ouabain; Plasma; Rubidium; Sodium | 1985 |
Na+ leak in erythrocytes from essential hypertensive patients.
Topics: Adult; Aged; Biological Transport; Bumetanide; Calcium; Cell Membrane Permeability; Erythrocytes; Female; Humans; Hydrogen-Ion Concentration; Hypertension; Kinetics; Lithium; Male; Middle Aged; Ouabain; Potassium; Sodium | 1985 |
Erythrocyte cation transport is sex-related and is modified by oral contraceptives.
Topics: Adult; Biological Transport, Active; Contraceptives, Oral; Erythrocytes; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Ouabain; Potassium; Sex Factors; Sodium | 1985 |
The effect of melittin on Na+ and Rb+ transport in cultured skin fibroblasts of the spontaneously hypertensive rat.
Topics: Animals; Bee Venoms; Biological Transport, Active; Cells, Cultured; Fibroblasts; Hypertension; Melitten; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rubidium; Skin; Sodium | 1985 |
Abnormal membrane sodium transport in Liddle's syndrome.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Biological Transport; Cell Membrane; Child; Erythrocytes; Ethacrynic Acid; Female; Humans; Hypertension; Hypokalemia; In Vitro Techniques; Male; Osmolar Concentration; Ouabain; Potassium; Renal Tubular Transport, Inborn Errors; Renin; Sodium; Sodium Isotopes | 1971 |
A possible etiology of contractility impairment of vascular smooth muscle from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Barium; Blood Pressure; Calcium; Cobalt; Hypertension; In Vitro Techniques; Lanthanum; Manganese; Muscle Contraction; Muscle, Smooth; Nitroglycerin; Norepinephrine; Organ Size; Ouabain; Papaverine; Potassium; Rats; Strontium; Vasoconstrictor Agents | 1973 |
Importance of the adrenergic nervous system in the support of cardiac function in patients with primary arterial hypertension.
Topics: Body Weight; Cardiac Output; Chlorthalidone; Digitalis Glycosides; Glomerular Filtration Rate; Guanethidine; Heart; Heart Failure; Humans; Hypertension; Ouabain; Receptors, Adrenergic; Reserpine; Sympathetic Nervous System; Sympatholytics | 1973 |
Ouabain-induced hypertension in a patient with decompensated hypertensive heart disease.
Topics: Aphasia; Cerebrovascular Disorders; Heart Failure; Hemiplegia; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Injections, Intravenous; Male; Middle Aged; Ouabain | 1973 |
The paced human heart. II. Hemodynamic and ballistocardiographic correlations after digitalis administation.
Topics: Aged; Ballistocardiography; Blood Pressure; Brachial Artery; Cardiac Output; Digitalis; Electrocardiography; Heart; Heart Block; Hemodynamics; Humans; Hypertension; Injections, Intravenous; Middle Aged; Ouabain; Pacemaker, Artificial; Phytotherapy; Plants, Medicinal; Plants, Toxic; Vascular Resistance | 1973 |
Barium-induced skeletal muscle paralysis in the rat, and its relationship to human familial periodic paralysis.
Topics: Adrenal Glands; Animals; Arrhythmias, Cardiac; Barium; Calcium; Female; Hypertension; Hypokalemia; Isoproterenol; Male; Muscle Contraction; Muscles; Muscular Diseases; Ouabain; Paralyses, Familial Periodic; Paralysis; Potassium; Propranolol; Rats; Sodium; Tubocurarine | 1974 |
The effect of stepwise doses of digitalis on hemodynamic function in man.
Topics: Administration, Oral; Animals; Cardiac Catheterization; Cardiac Output; Cardiomyopathies; Chagas Disease; Coronary Disease; Digitalis Glycosides; Digoxin; Dogs; Electrocardiography; Heart Diseases; Hemodynamics; Humans; Hypertension; Male; Mitral Valve Insufficiency; Ouabain; Oxygen Consumption; Phonocardiography | 1970 |
[The 1st lead of the carotid sphygmogram in valvular and arterial heart diseases].
Topics: Adolescent; Adult; Aged; Amyl Nitrite; Aortic Valve Insufficiency; Aortic Valve Stenosis; Arteriosclerosis; Carotid Arteries; Child; Digitalis Glycosides; Female; Humans; Hypertension; Isoproterenol; Male; Middle Aged; Mitral Valve Insufficiency; Mitral Valve Stenosis; Ouabain; Phenylephrine; Propranolol; Pulse | 1969 |
Effects of increased arterial pressure and positive inotropic agents on the severity of myocardial ischemia in the acutely depressed heart.
Topics: Animals; Arteries; Blood Pressure Determination; Coronary Disease; Digitalis Glycosides; Dogs; Heart; Heart Ventricles; Hypertension; Ischemia; Isoproterenol; Ligation; Ouabain; Oxygen Consumption; Prognosis | 1972 |
The hemodynamic effects of ouabain upon the diseased left ventricle.
Topics: Adult; Aortic Valve Stenosis; Arrhythmias, Cardiac; Blood Pressure; Cardiac Catheterization; Cardiac Output; Cardiomyopathies; Female; Heart Conduction System; Heart Rate; Heart Ventricles; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Ouabain | 1968 |