xanthine has been researched along with Hypertension in 14 studies
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Uric acid and oxidative stress promote cardiovascular diseases, including atherosclerosis and hypertension." | 7.73 | Allopurinol reduces neointimal hyperplasia in the carotid artery ligation model in spontaneously hypertensive rats. ( Hamada, T; Hisatome, I; Igawa, G; Igawa, O; Kaetsu, Y; Matsubara, K; Matsuura, T; Miake, J; Ogino, K; Shigemasa, C; Sugihara, S; Yamamoto, T; Yamamoto, Y; Yoshida, A, 2006) |
| "Serum uric acid and oxypurines (hypoxanthine and xanthine) renal excretion of uric acid and oxypurines as well as plasma adenosine deaminase activity and AMP deaminase activity were studied in 18 patients with essential hypertension and in 17 healthy subjects." | 7.68 | [Value of oxypurines and uric acid in plasma, renal excretion of oxypurines and uric acid as well as plasma adenosine deaminase and AMP deaminase activity in patients with essential hypertension]. ( Banaszak, F; Głuszek, J; Tykarski, A, 1993) |
| "Elevated serum uric acid concentration has been associated with high blood pressure (BP) and hypertension." | 3.85 | Associations of plasma uric acid and purine metabolites with blood pressure in children: the KOALA Birth Cohort Study. ( Arts, IC; Bierau, J; Boonen, A; Pijnenburg, W; Scheepers, LE; Staessen, JA; Stehouwer, CD; Thijs, C, 2017) |
| "Uric acid and oxidative stress promote cardiovascular diseases, including atherosclerosis and hypertension." | 3.73 | Allopurinol reduces neointimal hyperplasia in the carotid artery ligation model in spontaneously hypertensive rats. ( Hamada, T; Hisatome, I; Igawa, G; Igawa, O; Kaetsu, Y; Matsubara, K; Matsuura, T; Miake, J; Ogino, K; Shigemasa, C; Sugihara, S; Yamamoto, T; Yamamoto, Y; Yoshida, A, 2006) |
| "Our objective was to determine whether two methylxanthines, pentoxifylline (PTX) and allopurinol, would have beneficial effects on experimental pregnancy-induced pre-eclampsia- like disease in ewes." | 3.71 | Inhibitory effects of methylxanthines on the pre-eclamptic-like symptoms in ewes. ( Németh, I; Pintér, S; Tálosi, G, 2001) |
| "Serum uric acid and oxypurines (hypoxanthine and xanthine) renal excretion of uric acid and oxypurines as well as plasma adenosine deaminase activity and AMP deaminase activity were studied in 18 patients with essential hypertension and in 17 healthy subjects." | 3.68 | [Value of oxypurines and uric acid in plasma, renal excretion of oxypurines and uric acid as well as plasma adenosine deaminase and AMP deaminase activity in patients with essential hypertension]. ( Banaszak, F; Głuszek, J; Tykarski, A, 1993) |
| "Cerebral blood flow (CBF, by laser Doppler flowmetry) and extracellular cortical concentrations (by microdialysis) of adenosine, inosine, xanthine, hypoxanthine, and lactate were measured together with somatosensory evoked potentials (SEP) in chloralose-anaesthetized spontaneously hypertensive rats (SHR) during relative cerebral ischemia induced by hypotensive hemorrhage." | 3.67 | Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites. ( Carlsson, S; Hagberg, H; Sandberg, M; Skarphedinsson, JO; Thorén, P, 1989) |
| " Enhanced ROS production (especially superoxide anion) causes diminished NO bioavailability and leads to endothelial dysfunction, which occurs for example in impaired vasorelaxation." | 2.42 | [Oxidative stress in hypertension]. ( Bełtowski, J; Jamroz, A; Wójcicka, G, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scheepers, LE | 1 |
| Boonen, A | 1 |
| Pijnenburg, W | 1 |
| Bierau, J | 1 |
| Staessen, JA | 1 |
| Stehouwer, CD | 1 |
| Thijs, C | 1 |
| Arts, IC | 1 |
| Salim, S | 2 |
| Asghar, M | 2 |
| Chugh, G | 2 |
| Taneja, M | 2 |
| Xia, Z | 1 |
| Saha, K | 1 |
| Hovatta, I | 1 |
| Vollert, C | 1 |
| Vu, A | 1 |
| COHEN, BM | 2 |
| RODARI, T | 1 |
| Wójcicka, G | 1 |
| Bełtowski, J | 1 |
| Jamroz, A | 1 |
| Yamamoto, Y | 1 |
| Ogino, K | 1 |
| Igawa, G | 1 |
| Matsuura, T | 1 |
| Kaetsu, Y | 1 |
| Sugihara, S | 1 |
| Matsubara, K | 1 |
| Miake, J | 1 |
| Hamada, T | 1 |
| Yoshida, A | 1 |
| Igawa, O | 1 |
| Yamamoto, T | 1 |
| Shigemasa, C | 1 |
| Hisatome, I | 1 |
| Harkness, RA | 1 |
| Geirsson, RT | 1 |
| McFadyen, IR | 1 |
| Tykarski, A | 1 |
| Głuszek, J | 1 |
| Banaszak, F | 1 |
| Uehara, Y | 1 |
| Kawabata, Y | 1 |
| Hirawa, N | 1 |
| Takada, S | 1 |
| Nagata, T | 1 |
| Numabe, A | 1 |
| Iwai, J | 1 |
| Sugimoto, T | 1 |
| Maenishi, O | 1 |
| Ito, H | 1 |
| Suzuki, T | 1 |
| Klejewski, A | 1 |
| Szcześniak-Chmielecka, A | 1 |
| Zeromska-Cancellaro, M | 1 |
| Urbaniak, T | 1 |
| Tálosi, G | 1 |
| Németh, I | 1 |
| Pintér, S | 1 |
| Skarphedinsson, JO | 1 |
| Sandberg, M | 1 |
| Hagberg, H | 1 |
| Carlsson, S | 1 |
| Thorén, P | 1 |
1 review available for xanthine and Hypertension
| Article | Year |
|---|---|
[Oxidative stress in hypertension].
Topics: Animals; Antioxidants; Biological Availability; Endothelium, Vascular; Fibroblasts; Free Radical Sca | 2004 |
13 other studies available for xanthine and Hypertension
| Article | Year |
|---|---|
Associations of plasma uric acid and purine metabolites with blood pressure in children: the KOALA Birth Cohort Study.
Topics: Blood Pressure; Child; Cohort Studies; Cross-Sectional Studies; Diastole; Female; Humans; Hypertensi | 2017 |
Oxidative stress: a potential recipe for anxiety, hypertension and insulin resistance.
Topics: Animals; Anxiety; Hypertension; Insulin Resistance; Male; Oxidative Stress; Rats; Rats, Sprague-Dawl | 2010 |
Potential contribution of oxidative stress and inflammation to anxiety and hypertension.
Topics: Analysis of Variance; Animals; Anxiety; Brain; Brain-Derived Neurotrophic Factor; Buthionine Sulfoxi | 2011 |
Rauwolfia-barbiturate-xanthine mixtures in the treatment of hypertension.
Topics: Barbiturates; Humans; Hypertension; Phenobarbital; Rauwolfia; Reserpine; Theobromine; Xanthine; Xant | 1957 |
Rauwolfia-barbiturate-xanthine mixtures in the treatment of hypertension.
Topics: Barbiturates; Humans; Hypertension; Phenobarbital; Rauwolfia; Reserpine; Theobromine; Xanthine; Xant | 1957 |
Rauwolfia-barbiturate-xanthine mixtures in the treatment of hypertension.
Topics: Barbiturates; Humans; Hypertension; Phenobarbital; Rauwolfia; Reserpine; Theobromine; Xanthine; Xant | 1957 |
Rauwolfia-barbiturate-xanthine mixtures in the treatment of hypertension.
Topics: Barbiturates; Humans; Hypertension; Phenobarbital; Rauwolfia; Reserpine; Theobromine; Xanthine; Xant | 1957 |
[Combination of Rauwolfia serpentina with a new xanthine derivative in therapy of arterial hypertension].
Topics: Humans; Hypertension; Rauwolfia; Reserpine; Theophylline; Xanthine; Xanthines | 1957 |
Allopurinol reduces neointimal hyperplasia in the carotid artery ligation model in spontaneously hypertensive rats.
Topics: Allopurinol; Animals; Blood Pressure; Carotid Arteries; Cell Proliferation; Cells, Cultured; Heart R | 2006 |
Concentrations of hypoxanthine, xanthine, uridine and urate in amniotic fluid at caesarean section and the association of raised levels with prenatal risk factors and fetal distress.
Topics: Amniotic Fluid; Cesarean Section; Female; Fetal Distress; Fetal Hypoxia; Humans; Hypertension; Hypox | 1983 |
[Value of oxypurines and uric acid in plasma, renal excretion of oxypurines and uric acid as well as plasma adenosine deaminase and AMP deaminase activity in patients with essential hypertension].
Topics: Adenosine Deaminase; Adult; AMP Deaminase; Female; Humans; Hypertension; Hypoxanthine; Hypoxanthines | 1993 |
Possible radical scavenging properties of cicletanine and renal protection in Dahl salt sensitive rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Brain; Epoprostenol; Free Radical Sc | 1993 |
Acceleration of hypertensive cerebral injury by the inhibition of xanthine-xanthine oxidase system in stroke-prone spontaneously hypertensive rats.
Topics: Allopurinol; Amitrole; Animals; Brain; Catalase; Cerebral Cortex; Cerebrovascular Disorders; Enzyme | 1997 |
Plasma purine turnover metabolites in women with normal pregnancy and pregnancy complicated with induced hypertension as compared to fetal well-being indices.
Topics: Adult; Apgar Score; Blood Pressure; Diastole; Female; Gestational Age; Heart Rate, Fetal; Humans; Hy | 2000 |
Inhibitory effects of methylxanthines on the pre-eclamptic-like symptoms in ewes.
Topics: Albumins; Allopurinol; Animals; Bilirubin; Blood Pressure; Fasting; Female; Heme; Hypertension; Hypo | 2001 |
Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites.
Topics: Adenosine; Animals; Brain; Brain Ischemia; Cerebral Hemorrhage; Cerebrovascular Circulation; Extrace | 1989 |