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chelerythrine and Hypertension

chelerythrine has been researched along with Hypertension in 9 studies

chelerythrine : A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"The main objectives of this study were to investigate the effects of deoxycorticosterone acetate (DOCA)-induced hypertension on the aortic and mesenteric vascular responses to vasodilator and vasoconstrictor agents and also to elucidate whether protein kinase C (PKC) was involved in these responses, by using chelerythrine and calphostin C, the inhibitors of protein kinase C."3.72Endothelial dysfunction in aortic rings and mesenteric beds isolated from deoxycorticosterone acetate hypertensive rats: possible involvement of protein kinase C. ( Fatehi, M; Fatehi-Hassanabad, Z; Shahidi, MI, 2004)
"Hypertension was induced in rats by abdominal aortic banding (Ab)."1.32Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system. ( Csiszar, A; Kaminski, PM; Koller, A; Ungvari, Z; Wolin, MS, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's6 (66.67)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González Arbeláez, LF1
Ciocci Pardo, A1
Fantinelli, JC1
Mosca, SM1
Pavlova, OO1
Sahach, VF1
Solovĭov, AI1
Fatehi-Hassanabad, Z1
Fatehi, M1
Shahidi, MI1
Ungvari, Z1
Csiszar, A1
Kaminski, PM1
Wolin, MS1
Koller, A1
Plumb, RD1
El-Sherbeeny, NA1
Dixon, LJ1
Hughes, SM1
Devine, AB1
Leahey, WJ1
McVeigh, GE1
Jarajapu, YP1
Knot, HJ1
Ruan, X1
Arendshorst, WJ1
Rosen, B1
Barg, J1
Zimlichman, R1
Rocic, P1
Griffin, TM1
McRae, CN1
Lucchesi, PA1

Other Studies

9 other studies available for chelerythrine and Hypertension

ArticleYear
Cyclosporine-A mimicked the ischemic pre- and postconditioning-mediated cardioprotection in hypertensive rats: Role of PKCε.
    Experimental and molecular pathology, 2016, Volume: 100, Issue:2

    Topics: Animals; Benzophenanthridines; Calcium; Cardiotonic Agents; Cyclosporine; Cytochromes c; Enzyme Inhi

2016
[Effect of inhibiting protein kinase C on calcium sensitivity of contractile apparatus of vascular smooth muscle during vasospasms of different origins].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2003, Volume: 49, Issue:6

    Topics: Actin Cytoskeleton; Alkaloids; Animals; Benzophenanthridines; Calcium; Cell Hypoxia; Endothelium, Va

2003
Endothelial dysfunction in aortic rings and mesenteric beds isolated from deoxycorticosterone acetate hypertensive rats: possible involvement of protein kinase C.
    European journal of pharmacology, 2004, Jun-28, Volume: 494, Issue:2-3

    Topics: Acetylcholine; Alkaloids; Anesthesia; Animals; Aorta, Thoracic; Benzophenanthridines; Blood Pressure

2004
Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.
    The American journal of pathology, 2004, Volume: 165, Issue:1

    Topics: Acetophenones; Acetylcholine; Alkaloids; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; A

2004
NAD(P)H-dependent superoxide production in platelets: the role of angiotensin II and protein kinase C.
    Clinical biochemistry, 2005, Volume: 38, Issue:7

    Topics: Aged; Alkaloids; Angiotensin II; Angiotensin Receptor Antagonists; Benzophenanthridines; Blood Plate

2005
Relative contribution of Rho kinase and protein kinase C to myogenic tone in rat cerebral arteries in hypertension.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 289, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amides; Animals; Benzophenanthridines; Blo

2005
Role of protein kinase C in angiotensin II-induced renal vasoconstriction in genetically hypertensive rats.
    The American journal of physiology, 1996, Volume: 270, Issue:6 Pt 2

    Topics: Alkaloids; Angiotensin II; Animals; Antihypertensive Agents; Benzophenanthridines; Biphenyl Compound

1996
The effects of angiotensin II, endothelin-1, and protein kinase C inhibitor on DNA synthesis and intracellular calcium mobilization in vascular smooth muscle cells from young normotensive and spontaneously hypertensive rats.
    American journal of hypertension, 1999, Volume: 12, Issue:12 Pt 1-2

    Topics: Alkaloids; Angiotensin II; Animals; Benzophenanthridines; Calcium; Cells, Cultured; DNA; Endothelin-

1999
Altered PYK2 phosphorylation by ANG II in hypertensive vascular smooth muscle.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:2

    Topics: Alkaloids; Angiotensin II; Animals; Aorta, Thoracic; Benzophenanthridines; Calcium; Cells, Cultured;

2002