sodium fluoride has been researched along with Hypertension in 16 studies
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we investigated the protective effects of the methanol extract of Azadirachta indica (AI) against sodium fluoride (NaF)-induced hypertension and genotoxicity in rats." | 7.88 | Ameliorative effect of Azadirachta indica on sodium fluoride-induced hypertension through improvement of antioxidant defence system and upregulation of extracellular signal regulated kinase 1/2 signaling. ( Adedapo, AA; Adejumobi, OA; Ajibade, TO; Alaba, BA; Asenuga, ER; Ola-Davies, OE; Omóbòwálé, TO; Oyagbemi, AA; Yakubu, MA, 2018) |
| " This finding was concurrent with significantly increased serum bioavailability of nitric oxide in the hypertensive rats treated with L-arginine and lisinopril." | 5.91 | L-arginine and lisinopril supplementation protects against sodium fluoride-induced nephrotoxicity and hypertension by suppressing mineralocorticoid receptor and angiotensin-converting enzyme 3 activity. ( Adedapo, AA; Adedapo, AD; Adejumobi, OA; Adetona, MO; Ajibade, TO; Aro, AO; Awodele, OA; Kayoka-Kabongo, PN; McGaw, LJ; Nkadimeng, SM; Oguntibeju, OO; Ola-Davies, OE; Omobowale, TO; Oyagbemi, AA; Saba, AB; Tijani, MO; Yakubu, MA, 2023) |
| "Hypertension is one of the silent killers in the world with high mortality and morbidity." | 5.48 | Quercetin attenuates hypertension induced by sodium fluoride via reduction in oxidative stress and modulation of HSP 70/ERK/PPARγ signaling pathways. ( Adedapo, AA; Adejumobi, OA; Afolabi, JM; Ajibade, TO; Arojojoye, OA; Asenuga, ER; Falayi, OO; Hassan, FO; Ochigbo, GO; Ogunpolu, BS; Ola-Davies, OE; Omobowale, TO; Oyagbemi, AA; Saba, AB; Yakubu, MA, 2018) |
| "Rutin co-treatment with NaF normalized blood pressure, lowered Kim-1 and NF-κB expressions, and improved nitric oxide bioavailability." | 5.48 | Ameliorative effect of Rutin on sodium fluoride-induced hypertension through modulation of Kim-1/NF-κB/Nrf2 signaling pathway in rats. ( Adedapo, AA; Adejumobi, OA; Afolabi, JM; Ajibade, TO; Asenuga, ER; Ayodeji, F; Falayi, OO; Hassan, FO; Ogunpolu, BS; Ola-Davies, OE; Omobowale, TO; Oyagbemi, AA; Saba, AB; Yakubu, MA, 2018) |
| " Group A was the control group and received normal saline, Group B was exposed to NaF at 300 ppm (300 mg/L) in drinking water daily for a week, Groups C and D were exposed to 300 ppm (300 mg/L) of NaF and coadministered with Luteolin orally daily at a dosage of 100 mg/kg and 200 mg/kg for the same time point." | 5.48 | Luteolin-mediated Kim-1/NF-kB/Nrf2 signaling pathways protects sodium fluoride-induced hypertension and cardiovascular complications. ( Adedapo, AA; Adejumobi, OA; Afolabi, JM; Ajibade, TO; Asenuga, ER; Falayi, OO; Ogunpolu, BS; Ola-Davies, OE; Omobowale, TO; Oyagbemi, AA; Saba, AB; Yakubu, MA, 2018) |
| " In this study, we investigated the protective effects of the methanol extract of Azadirachta indica (AI) against sodium fluoride (NaF)-induced hypertension and genotoxicity in rats." | 3.88 | Ameliorative effect of Azadirachta indica on sodium fluoride-induced hypertension through improvement of antioxidant defence system and upregulation of extracellular signal regulated kinase 1/2 signaling. ( Adedapo, AA; Adejumobi, OA; Ajibade, TO; Alaba, BA; Asenuga, ER; Ola-Davies, OE; Omóbòwálé, TO; Oyagbemi, AA; Yakubu, MA, 2018) |
| "The aim of this study was to correlate linear (18)F-sodium fluoride accumulation in the femoral arteries as a measure of diffuse mineral deposition in medial elastocalcinosis with cardiovascular risk factors (RFs) and calcified plaque burden (CPB)." | 3.79 | Association of linear ¹⁸F-sodium fluoride accumulation in femoral arteries as a measure of diffuse calcification with cardiovascular risk factors: a PET/CT study. ( Bannas, P; Busch, JD; Derlin, T; Herrmann, J; Janssen, T; Mester, J; Münster, S; Treszl, A; Veldhoen, S, 2013) |
| " Since, losartan, an AT1 receptor antagonist, has been shown to attenuate the L-NAME-induced increase in blood pressure, we undertook the present studies to evaluate whether losartan-induced decreased blood pressure in this model of hypertension is associated with attenuation of enhanced expression of Gi proteins and adenylyl cyclase signalling." | 3.72 | Losartan-induced attenuation of blood pressure in L-NAME hypertensive rats is associated with reversal of the enhanced expression of Gi alpha proteins. ( Anand-Srivastava, MB; Hashim, S, 2004) |
| "Xerostomia is a common chronic health condition that affects a great number of adults and significantly deteriorates quality of life, such that treatment is necessary." | 2.77 | Evaluation of the efficacy of two mouthrinses formulated for the relief of xerostomia of diverse origin in adult subjects. ( Espinoza, I; Lozano, C; Morales-Bozo, I; Ortega-Pinto, A; Plaza, A; Rojas, G; Soto, L; Urzúa, B, 2012) |
| " This finding was concurrent with significantly increased serum bioavailability of nitric oxide in the hypertensive rats treated with L-arginine and lisinopril." | 1.91 | L-arginine and lisinopril supplementation protects against sodium fluoride-induced nephrotoxicity and hypertension by suppressing mineralocorticoid receptor and angiotensin-converting enzyme 3 activity. ( Adedapo, AA; Adedapo, AD; Adejumobi, OA; Adetona, MO; Ajibade, TO; Aro, AO; Awodele, OA; Kayoka-Kabongo, PN; McGaw, LJ; Nkadimeng, SM; Oguntibeju, OO; Ola-Davies, OE; Omobowale, TO; Oyagbemi, AA; Saba, AB; Tijani, MO; Yakubu, MA, 2023) |
| "Hypertension is one of the silent killers in the world with high mortality and morbidity." | 1.48 | Quercetin attenuates hypertension induced by sodium fluoride via reduction in oxidative stress and modulation of HSP 70/ERK/PPARγ signaling pathways. ( Adedapo, AA; Adejumobi, OA; Afolabi, JM; Ajibade, TO; Arojojoye, OA; Asenuga, ER; Falayi, OO; Hassan, FO; Ochigbo, GO; Ogunpolu, BS; Ola-Davies, OE; Omobowale, TO; Oyagbemi, AA; Saba, AB; Yakubu, MA, 2018) |
| "Rutin co-treatment with NaF normalized blood pressure, lowered Kim-1 and NF-κB expressions, and improved nitric oxide bioavailability." | 1.48 | Ameliorative effect of Rutin on sodium fluoride-induced hypertension through modulation of Kim-1/NF-κB/Nrf2 signaling pathway in rats. ( Adedapo, AA; Adejumobi, OA; Afolabi, JM; Ajibade, TO; Asenuga, ER; Ayodeji, F; Falayi, OO; Hassan, FO; Ogunpolu, BS; Ola-Davies, OE; Omobowale, TO; Oyagbemi, AA; Saba, AB; Yakubu, MA, 2018) |
| " Group A was the control group and received normal saline, Group B was exposed to NaF at 300 ppm (300 mg/L) in drinking water daily for a week, Groups C and D were exposed to 300 ppm (300 mg/L) of NaF and coadministered with Luteolin orally daily at a dosage of 100 mg/kg and 200 mg/kg for the same time point." | 1.48 | Luteolin-mediated Kim-1/NF-kB/Nrf2 signaling pathways protects sodium fluoride-induced hypertension and cardiovascular complications. ( Adedapo, AA; Adejumobi, OA; Afolabi, JM; Ajibade, TO; Asenuga, ER; Falayi, OO; Ogunpolu, BS; Ola-Davies, OE; Omobowale, TO; Oyagbemi, AA; Saba, AB; Yakubu, MA, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (18.75) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 8 (50.00) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Ajibade, TO | 6 |
| Awodele, OA | 1 |
| Tijani, MO | 1 |
| Adejumobi, OA | 5 |
| Adetona, MO | 1 |
| Oyagbemi, AA | 6 |
| Adedapo, AD | 1 |
| Omobowale, TO | 6 |
| Aro, AO | 1 |
| Ola-Davies, OE | 5 |
| Saba, AB | 4 |
| Adedapo, AA | 6 |
| Nkadimeng, SM | 1 |
| McGaw, LJ | 1 |
| Kayoka-Kabongo, PN | 1 |
| Oguntibeju, OO | 1 |
| Yakubu, MA | 6 |
| Alaba, BA | 1 |
| Asenuga, ER | 5 |
| Arojojoye, OA | 1 |
| Afolabi, JM | 3 |
| Ogunpolu, BS | 4 |
| Falayi, OO | 3 |
| Hassan, FO | 2 |
| Ochigbo, GO | 1 |
| Ayodeji, F | 1 |
| Janssen, T | 1 |
| Bannas, P | 1 |
| Herrmann, J | 1 |
| Veldhoen, S | 1 |
| Busch, JD | 1 |
| Treszl, A | 1 |
| Münster, S | 1 |
| Mester, J | 1 |
| Derlin, T | 1 |
| Picco, DC | 1 |
| Delbem, AC | 1 |
| Sassaki, KT | 1 |
| Sumida, DH | 1 |
| Antoniali, C | 1 |
| Adejumobi, AO | 1 |
| Ige, TM | 1 |
| Morales-Bozo, I | 1 |
| Rojas, G | 1 |
| Ortega-Pinto, A | 1 |
| Espinoza, I | 1 |
| Soto, L | 1 |
| Plaza, A | 1 |
| Lozano, C | 1 |
| Urzúa, B | 1 |
| Hashim, S | 1 |
| Anand-Srivastava, MB | 1 |
| Chatelain, P | 1 |
| Robberecht, P | 1 |
| De Neef, P | 1 |
| Camus, JC | 1 |
| Christophe, J | 1 |
| Chiu, TH | 1 |
| Chatziantoniou, C | 1 |
| Ruan, X | 1 |
| Arendshorst, WJ | 1 |
| Grekin, RJ | 1 |
| Dumont, CJ | 1 |
| Vollmer, AP | 1 |
| Watts, SW | 1 |
| Webb, RC | 1 |
| Yoshikawa, H | 1 |
| Fukuda, K | 1 |
| Baba, A | 1 |
| Nishio, H | 1 |
| Ueyama, T | 1 |
| Yoshikawa, A | 1 |
| Kuchii, M | 1 |
| Nishio, I | 1 |
| Masuyama, Y | 1 |
| Nelson, KM | 1 |
| Shepherd, RE | 1 |
| Spitzer, JA | 1 |
1 trial available for sodium fluoride and Hypertension
| Article | Year |
|---|---|
Evaluation of the efficacy of two mouthrinses formulated for the relief of xerostomia of diverse origin in adult subjects.
Topics: Adult; Aloe; Arthritis; Burning Mouth Syndrome; Cetylpyridinium; Citric Acid; Cross-Over Studies; De | 2012 |
15 other studies available for sodium fluoride and Hypertension
| Article | Year |
|---|---|
L-arginine and lisinopril supplementation protects against sodium fluoride-induced nephrotoxicity and hypertension by suppressing mineralocorticoid receptor and angiotensin-converting enzyme 3 activity.
Topics: Angiotensins; Animals; Antioxidants; Arginine; Blood Pressure; Dietary Supplements; Humans; Hyperten | 2023 |
Ameliorative effect of Azadirachta indica on sodium fluoride-induced hypertension through improvement of antioxidant defence system and upregulation of extracellular signal regulated kinase 1/2 signaling.
Topics: Animals; Antioxidants; Azadirachta; Blood Pressure; Drinking Water; Heart; Hypertension; Kidney; Mal | 2018 |
Quercetin attenuates hypertension induced by sodium fluoride via reduction in oxidative stress and modulation of HSP 70/ERK/PPARγ signaling pathways.
Topics: Animals; Antioxidants; Blood Pressure; Glutathione; HSP70 Heat-Shock Proteins; Humans; Hypertension; | 2018 |
Ameliorative effect of Rutin on sodium fluoride-induced hypertension through modulation of Kim-1/NF-κB/Nrf2 signaling pathway in rats.
Topics: Animals; Antioxidants; Blood Pressure; Cell Adhesion Molecules; Hypertension; Male; NF-E2-Related Fa | 2018 |
Luteolin-mediated Kim-1/NF-kB/Nrf2 signaling pathways protects sodium fluoride-induced hypertension and cardiovascular complications.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Catalase; Drug Administration Schedule; Electrocar | 2018 |
Association of linear ¹⁸F-sodium fluoride accumulation in femoral arteries as a measure of diffuse calcification with cardiovascular risk factors: a PET/CT study.
Topics: Adult; Aged; Aged, 80 and over; Calcinosis; Cardiovascular Diseases; Diabetes Complications; Female; | 2013 |
The effect of chronic treatment with fluoride on salivary activity, tooth, and bone in spontaneously hypertensive rats (SHR).
Topics: Amylases; Animals; Calcium; Femur; Hardness; Hypertension; Incisor; Proteins; Rats; Rats, Inbred SHR | 2014 |
Sodium fluoride induces hypertension and cardiac complications through generation of reactive oxygen species and activation of nuclear factor kappa beta.
Topics: Animals; Biomarkers; Cariostatic Agents; Hypertension; Kidney; Male; Malondialdehyde; Myocardium; NF | 2017 |
Losartan-induced attenuation of blood pressure in L-NAME hypertensive rats is associated with reversal of the enhanced expression of Gi alpha proteins.
Topics: Adenylyl Cyclases; Animals; Antihypertensive Agents; Blood Pressure; Colforsin; Disease Models, Anim | 2004 |
Thermodependence of basal and stimulated cardiac adenylate cyclase activity in normotensive and spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Guanylyl Imidodiphosphate; Hypertension; Kinetics; Magnes | 1983 |
Age-dependent changes in the myocardial adenylate cyclase of normotensive and spontaneously hypertensive rat.
Topics: Adenylyl Cyclases; Aging; Animals; Body Weight; Hypertension; Isoproterenol; Male; Microsomes; Muscl | 1981 |
Defective G protein activation of the cAMP pathway in rat kidney during genetic hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cholera Toxin; Cyclic AMP; Fenoldopam; GTP-Binding Proteins | 1995 |
Mechanisms in the pressor effects of hepatic portal venous fatty acid infusion.
Topics: Acetylcholine; Aldosterone; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pre | 1997 |
Deficient activity of nucleotide binding regulatory protein coupled with PGE2 receptor in renal medulla of spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Colforsin; Dinoprostone; GTP-Binding Proteins; Hypertension; Kidney Medu | 1990 |
Lipolysis and beta-adrenergic receptor binding on adipocytes of spontaneously hypertensive rats.
Topics: Adipose Tissue; Animals; Cyclic AMP; Dihydroalprenolol; Hypertension; Isoproterenol; Lipolysis; Rats | 1987 |