2-acetylaminofluorene has been researched along with Hypertension in 2 studies
2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The levels of N-acetoxy-2-acetylaminofluorene (NA-AAF)-induced unscheduled DNA synthesis (UDS) and of NA-AAF binding to DNA have been determined in resting mononuclear leukocytes from individuals with various smoking habits, heart infarct patients and subjects diagnosed for hypertension." | 7.66 | The effects of smoking, hypertension and cardiovascular disease on the estimation of unscheduled DNA synthesis and covalent binding to DNA induced by N-acetoxy-2-acetylaminofluorene in resting human mononuclear leukocytes. ( Bryngelsson, C; Bryngelsson, T; Franzén, J; Janzon, L; Johansson, BW; Lindholm, L; Pero, RW; Scherstén, B; Trell, E, 1983) |
| "The levels of N-acetoxy-2-acetylaminofluorene (NA-AAF)-induced unscheduled DNA synthesis (UDS) and of NA-AAF binding to DNA have been determined in resting mononuclear leukocytes from individuals with various smoking habits, heart infarct patients and subjects diagnosed for hypertension." | 3.66 | The effects of smoking, hypertension and cardiovascular disease on the estimation of unscheduled DNA synthesis and covalent binding to DNA induced by N-acetoxy-2-acetylaminofluorene in resting human mononuclear leukocytes. ( Bryngelsson, C; Bryngelsson, T; Franzén, J; Janzon, L; Johansson, BW; Lindholm, L; Pero, RW; Scherstén, B; Trell, E, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pero, RW | 1 |
| Bryngelsson, C | 1 |
| Bryngelsson, T | 2 |
| Lindholm, L | 2 |
| Scherstén, B | 1 |
| Trell, E | 1 |
| Janzon, L | 1 |
| Franzén, J | 1 |
| Johansson, BW | 1 |
| Pero, R | 1 |
2 other studies available for 2-acetylaminofluorene and Hypertension
| Article | Year |
|---|---|
The effects of smoking, hypertension and cardiovascular disease on the estimation of unscheduled DNA synthesis and covalent binding to DNA induced by N-acetoxy-2-acetylaminofluorene in resting human mononuclear leukocytes.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Aged; Cell Cycle; DNA; Humans; Hypertension; In V | 1983 |
Hypertension, age, and smoking related to genotoxic sensitivity in human lymphocytes: a population study.
Topics: 2-Acetylaminofluorene; Aged; Aging; Blood Pressure; Cardiovascular Diseases; DNA; Humans; Hypertensi | 1986 |