5-hydroxytryptophan has been researched along with Hypertension in 20 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These results suggest that chronic administration of L-5-HTP provides significant protection against the development of DOCA-induced hypertension, polydipsia, polyuria, and cardiac hypertrophy in rats." | 5.27 | Chronic treatment with L-5-hydroxytryptophan prevents the development of DOCA-salt-induced hypertension in rats. ( Fregly, MJ; Lockley, OE; Sumners, C, 1987) |
| " These results suggest that chronic administration of L-5-HTP was effective in reducing the elevated blood pressure in the DS model." | 1.28 | Reduction in the elevated blood pressure of Dahl salt-sensitive rats treated chronically with L-5-hydroxytryptophan. ( Baron, A; Fregly, MJ; Riesselmann, A, 1991) |
| "Cardiac hypertrophy was associated with Dahl salt-induced hypertension." | 1.28 | Reduction in the elevated blood pressure of Dahl salt-sensitive rats treated chronically with L-5-hydroxytryptophan. ( Baron, A; Fregly, MJ; Riesselmann, A, 1991) |
| " These results suggest that chronic administration of L-5-HTP provides significant protection against the development of DOCA-induced hypertension, polydipsia, polyuria, and cardiac hypertrophy in rats." | 1.27 | Chronic treatment with L-5-hydroxytryptophan prevents the development of DOCA-salt-induced hypertension in rats. ( Fregly, MJ; Lockley, OE; Sumners, C, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (85.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borroni, E | 1 |
| Bohrmann, B | 1 |
| Grueninger, F | 1 |
| Prinssen, E | 1 |
| Nave, S | 1 |
| Loetscher, H | 1 |
| Chinta, SJ | 1 |
| Rajagopalan, S | 1 |
| Rane, A | 1 |
| Siddiqui, A | 1 |
| Ellenbroek, B | 1 |
| Messer, J | 1 |
| Pähler, A | 1 |
| Andersen, JK | 1 |
| Wyler, R | 1 |
| Cesura, AM | 1 |
| Maron, E | 1 |
| Tõru, I | 1 |
| Vasar, V | 1 |
| Shlik, J | 1 |
| Yao, T | 1 |
| Andersson, S | 1 |
| Thoren, P | 1 |
| Nagatsu, T | 1 |
| Fuller, RW | 1 |
| Holland, DR | 1 |
| Yen, TT | 1 |
| Bemis, KG | 1 |
| Stamm, NB | 1 |
| Lindqvist, M | 1 |
| Kehr, W | 1 |
| Carlsson, A | 1 |
| Baron, A | 1 |
| Riesselmann, A | 1 |
| Fregly, MJ | 2 |
| Koulu, M | 1 |
| Saavedra, JM | 1 |
| Bjelogrlic, N | 1 |
| Niwa, M | 1 |
| Agren, H | 1 |
| Linnoila, M | 1 |
| Itskovitz, HD | 2 |
| Werber, JL | 1 |
| Sheridan, AM | 1 |
| Brewer, TF | 2 |
| Stier, CT | 2 |
| Lockley, OE | 1 |
| Sumners, C | 1 |
| Tsai, CF | 1 |
| Lin, MT | 1 |
| Dick, LB | 1 |
| Wynn, N | 1 |
| Denoroy, L | 1 |
| Tappaz, ML | 1 |
| Fety, R | 1 |
| Vincent, M | 1 |
| Renaud, B | 1 |
| Sassard, J | 1 |
| O'Steen, WK | 1 |
| Hall, CE | 1 |
| Hall, OS | 1 |
| Nath, K | 1 |
| Agarwal, SN | 1 |
| Mittal, HS | 1 |
| Singh, KN | 1 |
| Saxena, S | 1 |
| Pant, H | 1 |
| Grollman, A | 1 |
| Krishnamurty, VS | 1 |
| Wardle, EN | 1 |
| Laborit, H | 1 |
| Ozaki, M | 1 |
| Tabei, R | 1 |
| Spector, S | 1 |
| Louis, WJ | 1 |
| Sjoerdsma, A | 1 |
1 trial available for 5-hydroxytryptophan and Hypertension
| Article | Year |
|---|---|
The effect of 5-hydroxytryptophan on cholecystokinin-4-induced panic attacks in healthy volunteers.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adolescent; Adult; Capsules; Cognition Disorders; Double- | 2004 |
19 other studies available for 5-hydroxytryptophan and Hypertension
| Article | Year |
|---|---|
Sembragiline: A Novel, Selective Monoamine Oxidase Type B Inhibitor for the Treatment of Alzheimer's Disease.
Topics: 5-Hydroxytryptophan; Acetamides; Alzheimer Disease; Animals; Astrocytes; Gliosis; Humans; Hypertensi | 2017 |
Long-lasting cardiovascular depressor response following sciatic stimulation in spontaneously hypertensive rats. Evidence for the involvement of central endorphin and serotonin systems.
Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Brompheniramine; Dexamethasone; Electric Stimulation; | 1982 |
[Tyrosine hydroxylase (author's transl)].
Topics: 5-Hydroxytryptophan; Adrenal Glands; Brain; Catecholamines; Chemical Phenomena; Chemistry; Coenzymes | 1976 |
Antihypertensive effects of fluoxetine and L-5-hydroxytryptophan in rats.
Topics: 5-Hydroxytryptophan; Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Drug In | 1979 |
Attempts to measure endogenous levels of dopa and 5-hydroxytryptophan in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Brain Chemistry; Chlorpromazine; Dihydroxyphenylalanine; | 1975 |
Reduction in the elevated blood pressure of Dahl salt-sensitive rats treated chronically with L-5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Body Weight; Cardiomegaly; Desoxycorticosterone; Femal | 1991 |
Serotonin turnover in discrete hypothalamic nuclei and mesencephalic raphe nuclei of young and adult spontaneously hypertensive rats.
Topics: 5-Hydroxytryptophan; Aging; Animals; Hydroxyindoleacetic Acid; Hypertension; Hypothalamus; Kinetics; | 1986 |
5-Hydroxytryptophan and carbidopa in spontaneously hypertensive rats.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain; C | 1989 |
Chronic treatment with L-5-hydroxytryptophan prevents the development of DOCA-salt-induced hypertension in rats.
Topics: 5-Hydroxytryptophan; Administration, Cutaneous; Angiotensin II; Animals; Cardiomegaly; Catecholamine | 1987 |
Pain sensitivity, thermal capability, and brain monoamine turnover in hypertensive rats.
Topics: 5-Hydroxytryptophan; Amines; Animals; Body Temperature Regulation; Brain; Dihydroxyphenylalanine; Hy | 1987 |
Formation of biogenic amines by isolated kidneys of spontaneously hypertensive rats.
Topics: 5-Hydroxytryptophan; Animals; Dopamine; Hypertension; Kidney; Levodopa; Norepinephrine; Perfusion; R | 1986 |
Rate of tryptophan hydroxylation in vivo in brain nuclei of genetically hypertensive rats of the Lyon strain.
Topics: 5-Hydroxytryptophan; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Hydrazines | 1985 |
Hormone influenced hypertension in the male rat. Effect of hydrochlorothiazide.
Topics: 5-Hydroxytryptophan; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiomegaly; Ce | 1969 |
Urinary 5-hydroxyindoleacetic acid in cases of hypertension before and after therapy with guanethidine and methyldopa.
Topics: 5-Hydroxytryptophan; Guanethidine; Humans; Hydroxyindoleacetic Acid; Hypertension; Methyldopa; Serot | 1972 |
Contractile response of the aorta of the normotensive and acute and chronic hypertensive rat.
Topics: 5-Hydroxytryptophan; Acute Disease; Animals; Aorta; Blood Pressure; Calcium; Chronic Disease; Dose-R | 1973 |
The relevance of intravascular coagulation to pre-eclampsia.
Topics: 5-Hydroxytryptophan; Abruptio Placentae; Animals; Blood Coagulation Factors; Desoxycorticosterone; D | 1973 |
[Advantages of restoring the granular catecholamine stock and of SH groups in the treatment of so-called "irreversible" hemorrhagic shock].
Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Cell Membrane Permeability; Chlorpromazine; Dogs; Dopa | 1969 |
Metabolism of monoamines in spontaneously hypertensive rat.
Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Brain; Hypertension; Kidney; Liver; Male; Monoamine Ox | 1966 |
Antihypertensive and noradrenaline-depleting effects of alpha-methyl-5-hydroxytryptophan in the rat.
Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Brain Stem; Female; Hydrazines; Hypertension; Methylty | 1969 |