theobromine has been researched along with Hypertension in 23 studies
Theobromine: 3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
theobromine : A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The bioavailability of this polyphenol-rich cocoa powder developed at pilot scale was previously demonstrated in humans." | 1.35 | Antihypertensive effect of a polyphenol-rich cocoa powder industrially processed to preserve the original flavonoids of the cocoa beans. ( Aleixandre, A; Cienfuegos-Jovellanos, E; Miguel, M; Moulay, L; Muguerza, B; Quiñones, Mdel M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (78.26) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.70) | 29.6817 |
| 2010's | 3 (13.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, SB | 1 |
| Li, YF | 1 |
| Mao, ZF | 1 |
| Hu, HH | 1 |
| Ouyang, SH | 1 |
| Wu, YP | 1 |
| Tsoi, B | 1 |
| Gong, P | 1 |
| Kurihara, H | 1 |
| He, RR | 1 |
| Guessous, I | 1 |
| Pruijm, M | 1 |
| Ponte, B | 1 |
| Ackermann, D | 1 |
| Ehret, G | 1 |
| Ansermot, N | 1 |
| Vuistiner, P | 1 |
| Staessen, J | 1 |
| Gu, Y | 1 |
| Paccaud, F | 1 |
| Mohaupt, M | 1 |
| Vogt, B | 1 |
| Pechère-Bertschi, A | 1 |
| Pechère-Berstchi, A | 1 |
| Martin, PY | 1 |
| Burnier, M | 1 |
| Eap, CB | 1 |
| Bochud, M | 1 |
| Cienfuegos-Jovellanos, E | 1 |
| Quiñones, Mdel M | 1 |
| Muguerza, B | 1 |
| Moulay, L | 1 |
| Miguel, M | 1 |
| Aleixandre, A | 1 |
| HACKENBERG, R | 1 |
| HAUSLER, HP | 1 |
| JOB, C | 1 |
| ZELLNER, H | 1 |
| COHEN, BM | 2 |
| KORTGE, P | 1 |
| KUHNE, P | 1 |
| SCHULTZ, GW | 1 |
| SCHENK, H | 1 |
| FRANKE, G | 1 |
| THIEME, HJ | 1 |
| BECKMANN, G | 1 |
| CARLIZZA, L | 1 |
| FUJIHARA, M | 1 |
| TAKAHASHI, I | 1 |
| HAYASHI, K | 1 |
| TANAKA, M | 1 |
| Fahim, M | 1 |
| Mustafa, SJ | 1 |
| Dembowski, U | 1 |
| Marx-Heep, I | 1 |
| Adams, HJ | 1 |
| Tikhonov, VP | 1 |
| Statsenko, ME | 1 |
| Trimarco, B | 1 |
| Lembo, G | 1 |
| De Luca, N | 1 |
| Ricciardelli, B | 1 |
| Rosiello, G | 1 |
| Volpe, M | 1 |
| Orofino, G | 1 |
| Condorelli, M | 1 |
| Quirk, WS | 1 |
| Dengerink, HA | 1 |
| Bademian, MJ | 1 |
| Hall, KW | 1 |
| Wright, JW | 1 |
| Iunusov, RA | 1 |
| Burykh, LN | 1 |
| Sviridova, NI | 1 |
| Shoĭkhet, IN | 1 |
| Treĭvish, VS | 1 |
| Novikova, NN | 1 |
| Rafibekova, ZhS | 1 |
| Radzvilovskaia, ME | 1 |
| Bobusheva, GS | 1 |
| Dzhumagulova, AS | 1 |
| Solerte, SB | 1 |
| Adamo, S | 1 |
| Viola, C | 1 |
| Zambianchi, E | 1 |
| Ferrari, E | 1 |
| Dammann, C | 1 |
3 trials available for theobromine and Hypertension
| Article | Year |
|---|---|
Effects of celiprolol on systemic and forearm circulation in hypertensive patients: a double-blind cross-over study versus metoprolol.
Topics: Adrenergic beta-Antagonists; Adult; Celiprolol; Double-Blind Method; Echocardiography; Female; Forea | 1987 |
[Pentoxifylline and arterial hypertension in diabetes mellitus: long-term results in randomized groups].
Topics: Diabetes Complications; Erythrocyte Deformability; Follow-Up Studies; Humans; Hypertension; Pentoxif | 1985 |
[Experiences with new Cosaldon forms].
Topics: Adult; Aged; Arteriosclerosis; Cholesterol; Dosage Forms; Female; Geriatrics; Humans; Hypertension; | 1969 |
20 other studies available for theobromine and Hypertension
| Article | Year |
|---|---|
Differing chemical compositions of three teas may explain their different effects on acute blood pressure in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Caffeine; Camellia sinensis; Epinephrine; Hypertension; Male; Norepinephrin | 2015 |
Associations of ambulatory blood pressure with urinary caffeine and caffeine metabolite excretions.
Topics: Adult; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Caffeine; Circadian Rhythm | 2015 |
Correction.
Topics: Adult; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Caffeine; Circadian Rhythm | 2016 |
Antihypertensive effect of a polyphenol-rich cocoa powder industrially processed to preserve the original flavonoids of the cocoa beans.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cacao; Flavonoids; Food Handling; Hypertension; Ma | 2009 |
[New perspectives in therapy of hypertonic symptom complex].
Topics: Barbiturates; Humans; Hypertension; Papaverine; Theobromine | 1953 |
[Pharmacological and clinical studies of a water-soluble theobromine derivative. II].
Topics: Angina Pectoris; Arteriosclerosis; Biomedical Research; Hypertension; Theobromine; Vasoconstrictor A | 1954 |
Rauwolfia-barbiturate-xanthine mixtures in the treatment of hypertension.
Topics: Barbiturates; Humans; Hypertension; Phenobarbital; Rauwolfia; Reserpine; Theobromine; Xanthine; Xant | 1957 |
Rauwolfia-barbiturate-xanthine mixtures in the treatment of hypertension.
Topics: Barbiturates; Humans; Hypertension; Phenobarbital; Rauwolfia; Reserpine; Theobromine; Xanthine; Xant | 1957 |
Rauwolfia-barbiturate-xanthine mixtures in the treatment of hypertension.
Topics: Barbiturates; Humans; Hypertension; Phenobarbital; Rauwolfia; Reserpine; Theobromine; Xanthine; Xant | 1957 |
Rauwolfia-barbiturate-xanthine mixtures in the treatment of hypertension.
Topics: Barbiturates; Humans; Hypertension; Phenobarbital; Rauwolfia; Reserpine; Theobromine; Xanthine; Xant | 1957 |
[Analysis of circulation in hypertensive patients after parenteral administration of hydrosoluble theobromine derivatives].
Topics: Biological Phenomena; Blood Circulation; Hypertension; Pharmaceutical Preparations; Physiological Ph | 1957 |
[Therapy of hypertension].
Topics: Antihypertensive Agents; Digitalis; Humans; Hypertension; Secologanin Tryptamine Alkaloids; Theobrom | 1958 |
[Therapy of hypertension with a Rauwolfia combination preparation].
Topics: Alkaloids; Antihypertensive Agents; Digitalis; Digitalis Glycosides; Humans; Hypertension; Rauwolfia | 1958 |
[Treatment of hypertension in geriatrics].
Topics: Aged; Geriatrics; Humans; Hypertension; Oleic Acid; Oleic Acids; Theobromine | 1959 |
[Clinical experimentation with a hydrosoluble derivative of theobromine].
Topics: Asthma; Cardiovascular Diseases; Empirical Research; Hypertension; Research Design; Theobromine | 1961 |
[Experiences with the use of Tonostan tablets].
Topics: Humans; Hypertension; Niacin; Nicotinic Acids; Tablets; Theobromine | 1961 |
Evidence for the presence of A(1) adenosine receptors in the aorta of spontaneously hypertensive rats.
Topics: Adenine; Adenosine; Animals; Aorta; Culture Techniques; Dose-Response Relationship, Drug; Endotheliu | 2001 |
[Angioneuropathies, angiolopathies and other disorders of blood circulation. Treatment in ambulatory patients].
Topics: Adult; Aged; Drug Evaluation; Female; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Obes | 1979 |
[Pharmacologic correction of the adverse effects of beta-adrenoblockaders on the kidneys in patients with hypertension].
Topics: Adult; Aged; Female; Humans; Hypertension; Ischemia; Kidney; Male; Middle Aged; Pentoxifylline; Prop | 1989 |
The effects of pentoxifylline on cochlear blood flow in normotensive and spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cochlea; Dose-Response Relationship, Drug; Hypertension; Infusions, Intrave | 1988 |
[Hemodynamic assessment of anti-angina preparations in treating patients with ischemic heart disease with hypertension].
Topics: Adult; Aged; Coronary Disease; Drug Evaluation; Drug Therapy, Combination; Female; Hemodynamics; Hum | 1987 |
[Pentoxifylline (Trental) in the treatment of chronic glomerulonephritis].
Topics: Adolescent; Adult; Chronic Disease; Drug Evaluation; Female; Glomerulonephritis; Humans; Hypertensio | 1986 |
[Experience with the use of trental in the treatment of essential hypertension].
Topics: Adult; Antihypertensive Agents; Blood Coagulation; Female; Humans; Hypertension; Male; Middle Aged; | 1985 |