pentylenetetrazole has been researched along with Hypertension in 8 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was to examine the effect on the blood-brain barrier function of a rapid blood pressure elevation and the duration of this pressure during bicuculline and pentylenetetrazol-induced seizures." | 3.68 | The effect of acute hypertension on blood-brain barrier permeability to albumin during experimentally induced epileptic seizures. ( Kaya, M; Oztaş, B, 1991) |
| "In rabbits subjected to bicuculline (BC)- or pentylenetetrazole (PTZ)-seizures of 3 or 20 min duration or to adrenaline-induced hypertension, specific gravity (SG) was measured bilaterally in 15 regional brain areas in order to detect possible associations between the regionally limited blood-brain barrier openings due to these insults (see Nitsch and Klatzo 1983) and the presence of brain edema." | 3.67 | Specific gravity increases and brain water content decreases during short epileptiform seizures in discrete rabbit brain areas. ( Fujiwara, K; Klatzo, I; Kuroiwa, T; Nitsch, C, 1984) |
| "Pentylenetetrazol-induced seizure produces less disruption of the blood-brain barrier in right cerebral hemisphere than in left cerebral hemisphere in female rats." | 1.30 | Asymmetrical changes in blood-brain barrier permeability during pentylenetetrazol-induced seizures and in acute hypertension. ( Oztaş, B, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MORIN, G | 2 |
| CORRIOL, J | 2 |
| Nitsch, C | 1 |
| Fujiwara, K | 1 |
| Kuroiwa, T | 1 |
| Klatzo, I | 1 |
| Oztaş, B | 2 |
| Kaya, M | 1 |
| Chen, G | 1 |
| Ensor, CR | 1 |
| Bohner, B | 1 |
| Secor, HV | 1 |
| DeBardeleben, JF | 1 |
| Beleslin, BB | 1 |
| Beleslin, DB | 1 |
8 other studies available for pentylenetetrazole and Hypertension
| Article | Year |
|---|---|
[Mechanism of arterial hypertension produced by intravenous injection of cardiazol dogs treated with curare and in dogs treated and not treated with chloralose].
Topics: Animals; Chloralose; Curare; Dogs; Hypertension; Hypnotics and Sedatives; Injections, Intravenous; P | 1955 |
[Relation between the hypertensive and epiletogen effects of penta-methylene-tetrazole].
Topics: Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Pentylenetetrazole; Rubiaceae; S | 1957 |
Specific gravity increases and brain water content decreases during short epileptiform seizures in discrete rabbit brain areas.
Topics: Animals; Bicuculline; Blood; Blood-Brain Barrier; Body Water; Brain; Epilepsy; Epinephrine; Hyperten | 1984 |
Asymmetrical changes in blood-brain barrier permeability during pentylenetetrazol-induced seizures and in acute hypertension.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Capillary Permeability; Convulsants; Female; Functiona | 1998 |
The effect of acute hypertension on blood-brain barrier permeability to albumin during experimentally induced epileptic seizures.
Topics: Acute Disease; Albumins; Animals; Bicuculline; Blood Pressure; Blood-Brain Barrier; Evans Blue; Fema | 1991 |
The pharmacology of 2-(ethylamino)-2-(2-thienyl)-cyclohexanone-HCl (CI-634).
Topics: Anesthesia, General; Animals; Blood Pressure; Cardiovascular System; Catalepsy; Cats; Central Nervou | 1969 |
Syntheses and screening of some trifluoromethyl pyrazoles.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antifungal Agents; Blood Pressure; Fluorin | 1971 |
On the mechanism of hypertensive effect of leptazol.
Topics: Animals; Blood Pressure; Female; Hypertension; Male; Pentylenetetrazole; Rats | 1967 |