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hydroflumethiazide and Hypertension

hydroflumethiazide has been researched along with Hypertension in 43 studies

Hydroflumethiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p822)
hydroflumethiazide : A benzothiadiazine consisting of a 3,4-dihydro-HH-1,2,4-benzothiadiazine bicyclic system dioxygenated on sulfur and carrying trifluoromethyl and aminosulfonyl groups at positions 6 and 7 respectively. A diuretic with actions and uses similar to those of hydrochlorothiazide.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"5 mg and atenolol 50 mg (C-A) in adult black patients with mild to moderate hypertension (a resting supine diastolic blood pressure (DBP) between 95 and 115 mmHg after a two week placebo washout period)."9.07Randomised double-blind comparative study of efficacy and safety of hydroflumethiazide and reserpine and chlortalidone and atenolol in the treatment of mild to moderate hypertension in black patients. ( Maharaj, B; van der Byl, K, 1993)
"A retrospective analysis revealed that 125 geriatric patients had been treated for mild to moderate essential hypertension with a combination drug, each tablet of which contained 50 mg of hydroflumethiazide and 0."7.66Hypertension in the elderly: review of therapy with a hydroflumethiazide-reserpine combination. ( Elkowitz, EB, 1979)
"Propranolol treatment significantly reduced HDL-cholesterol (p < 0."6.67Metabolic effects of propranolol and hydroflumethiazide treatment in Kenyans with mild to moderate essential hypertension. ( Ogola, EN; Orinda, DA; Yonga, GO, 1993)
"Minoxidil seems to be a safe and potent antihypertensive drug for long-term use in severe arterial hypertension, but it cannot be recommended for routine treatment."5.26Long-term experiences with minoxidil in combination treatment of severe arterial hypertension. ( Lederballe Pedersen, O, 1977)
"5 mg and atenolol 50 mg (C-A) in adult black patients with mild to moderate hypertension (a resting supine diastolic blood pressure (DBP) between 95 and 115 mmHg after a two week placebo washout period)."5.07Randomised double-blind comparative study of efficacy and safety of hydroflumethiazide and reserpine and chlortalidone and atenolol in the treatment of mild to moderate hypertension in black patients. ( Maharaj, B; van der Byl, K, 1993)
" The prior treatment of hypertension was achieved by administration of hydroflumethiazide (120 mg/kg/day) and captopril (15-30 mg/kg/day) orally for 4-6 weeks by mixing in drinking water."3.67[Effect of long-term prior antihypertensive treatment on cerebral ischemia induced by bilateral common carotid artery ligation in SHRSR]. ( Inamura, K; Katayama, Y; Nagazumi, A; Shimizu, J; Soeda, T; Sugimoto, S; Suzuki, S; Terashi, A, 1986)
"A retrospective analysis revealed that 125 geriatric patients had been treated for mild to moderate essential hypertension with a combination drug, each tablet of which contained 50 mg of hydroflumethiazide and 0."3.66Hypertension in the elderly: review of therapy with a hydroflumethiazide-reserpine combination. ( Elkowitz, EB, 1979)
"Iodine metabolism and thyroid hormones in blood were studied in 19 men and 11 women who had been treated with thiazides for arterial hypertension from 1 month to 15 years."3.66Influence of thiazides on thyroid parameters in man. ( Bech, K; Hansen, JM; Siersbaek-Nielsen, K; Skovsted, L, 1978)
"Propranolol treatment significantly reduced HDL-cholesterol (p < 0."2.67Metabolic effects of propranolol and hydroflumethiazide treatment in Kenyans with mild to moderate essential hypertension. ( Ogola, EN; Orinda, DA; Yonga, GO, 1993)
" Although the three treatment regimens were similar with respect to safety and efficacy, the reserpine-hydroflumethiazide combination offers the advantages of more convenient dosage at lower cost."2.65Step 2 regimens in hypertension. An assessment. ( Berry, C; Finnerty, FA; Gyftopoulos, A; McKenney, A, 1979)
"Minoxidil seems to be a safe and potent antihypertensive drug for long-term use in severe arterial hypertension, but it cannot be recommended for routine treatment."1.26Long-term experiences with minoxidil in combination treatment of severe arterial hypertension. ( Lederballe Pedersen, O, 1977)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199039 (90.70)18.7374
1990's4 (9.30)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HOBOLTH, N1
GILLHESPY, RO1
VERTES, V1
KATZ, JB1
ROBINOW, SH1
KLINDER, G1
ARMASCRUZ, R1
GOMEZ, R1
MARDONES, J1
PLAZADELOSREYES, M1
STRASBURGER, KH1
KLEPZIG, H1
SEIFFERT, K1
CHRISTIANSEN, J1
HAGERUP, L1
NIELSEN, B1
Kadota, I1
Nishimura, Y1
Ishigami, R1
Yoshida, A1
Kristensen, BO1
Akbar, FA1
Boston, PF1
Chapman, J1
Pearce, MY1
Gifford, RW1
Williams, GW1
Vidt, DG1
Bolen, K1
Acker, C1
Andersen, GS1
Yonga, GO2
Ogola, EN2
Orinda, DA1
Maharaj, B1
van der Byl, K1
Salako, BL1
Kadiri, S1
Pedersen, OL1
Lederballe Pedersen, O1
Elkowitz, EB1
Bech, K1
Skovsted, L1
Siersbaek-Nielsen, K1
Hansen, JM1
Finnerty, FA1
Gyftopoulos, A1
Berry, C1
McKenney, A1
Iriuchijima, J2
Numao, Y2
Olatunde, A1
Akinkugbe, OO1
Carlisle, R1
Inatome, T1
Suzuki, S1
Katayama, Y1
Sugimoto, S1
Inamura, K1
Shimizu, J1
Soeda, T1
Nagazumi, A1
Terashi, A1
Suzuki, Y2
Ina, K1
Yamada, H1
Yamagami, I2
Salako, LA2
Tanaka, N1
Takenouchi, A1
Kjaerulff, J1
Lyngsoe, J1
Jamil, MA1
Cangiano, JL1
Bloomfield, DK1
Kojima, K1
Shinoda, M1
Beevers, DG1
Hamilton, M1
Harpur, JE1
Chiba, Y1
Fukuda, Y1
Kondo, K1
Sakuma, K1
Morioka, M1
Jitsukawa, H1
Imai, T1
Szadkowski, D1
Kann, J1
Gjonnaess, H1
Heimsoth, V1
Hartmann, F1
Damany, SJ1
Munshi, SG1
Shah, RM1

Trials

10 trials available for hydroflumethiazide and Hypertension

ArticleYear
Spironolactone and hydroflumethiazide in the treatment of hypertension.
    The British journal of clinical practice, 1981, Volume: 35, Issue:9

    Topics: Adult; Aged; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydroflumethiazide; Hypert

1981
Metabolic effects of propranolol and hydroflumethiazide treatment in Kenyans with mild to moderate essential hypertension.
    East African medical journal, 1993, Volume: 70, Issue:11

    Topics: Adolescent; Adult; Aged; Drug Monitoring; Female; Humans; Hydroflumethiazide; Hypertension; Kenya; M

1993
Randomised double-blind comparative study of efficacy and safety of hydroflumethiazide and reserpine and chlortalidone and atenolol in the treatment of mild to moderate hypertension in black patients.
    Journal of human hypertension, 1993, Volume: 7, Issue:5

    Topics: Adult; Antihypertensive Agents; Atenolol; Black People; Chlorthalidone; Double-Blind Method; Drug Co

1993
Comparative study of the efficacy and tolerability of hydroflumethiazide versus propranolol in Africans with mild to moderate hypertension.
    East African medical journal, 1993, Volume: 70, Issue:5

    Topics: Adult; Aged; Black People; Blood Pressure; Diastole; Female; Humans; Hydroflumethiazide; Hypertensio

1993
Step 2 regimens in hypertension. An assessment.
    JAMA, 1979, Feb-09, Volume: 241, Issue:6

    Topics: Adult; Aged; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydroflumethiazide; Hyperten

1979
A spironolactone-hydroflumethiazide combination in hypertension.
    The Practitioner, 1971, Volume: 206, Issue:233

    Topics: Adult; Aged; Chlorides; Clinical Trials as Topic; Drug Synergism; Female; Humans; Hydroflumethiazide

1971
A comparative study of spironolactone and hydroflumethiazide alone and together in the treatment of hypertension.
    Guy's Hospital reports, 1971, Volume: 120, Issue:3

    Topics: Administration, Oral; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations;

1971
A double-blind evaluation of the therapeutic efficacy of salutensin versus hydropres-50 in essential hypertension.
    Current therapeutic research, clinical and experimental, 1970, Volume: 12, Issue:2

    Topics: Adult; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; Hydroflumethiazide; Hypertensi

1970
An experiment of prophylactic medication for those with mild hypertension in population.
    Japanese circulation journal, 1965, Volume: 29, Issue:8

    Topics: Adult; Clinical Trials as Topic; Humans; Hydroflumethiazide; Hypertension; Middle Aged; Placebos; Re

1965
[On the treatment of hypertension].
    Die Medizinische Welt, 1965, Sep-11, Volume: 37

    Topics: Clinical Trials as Topic; Humans; Hydroflumethiazide; Hypertension; Phytotherapy; Plants, Medicinal;

1965

Other Studies

33 other studies available for hydroflumethiazide and Hypertension

ArticleYear
Hypotensive action of hydroflumethiazide.
    Acta medica Scandinavica, 1960, Sep-21, Volume: 168

    Topics: Chlorothiazide; Hydroflumethiazide; Hypertension; Hypotension

1960
The antihypertensive activity of hydroflumethiazide with Rauwolfia.
    Journal of the Irish Medical Association, 1962, Volume: 50

    Topics: Alkaloids; Antihypertensive Agents; Chlorothiazide; Hydroflumethiazide; Hypertension; Hypnotics and

1962
Comparison of short term metabolic effects of hydroflumethiazide and hydrochlorothiazide.
    Journal of chronic diseases, 1962, Volume: 15

    Topics: Chlorothiazide; Heart Failure; Humans; Hydrochlorothiazide; Hydroflumethiazide; Hypertension; Ions;

1962
[Treatment of hypertension in long-term patients].
    Deutsches medizinisches Journal, 1963, May-05, Volume: 14

    Topics: Alkaloids; Humans; Hydroflumethiazide; Hypertension; Hypnotics and Sedatives; Rauwolfia

1963
[NATRIURETIC DRUGS].
    Revista medica de Chile, 1963, Volume: 91

    Topics: Acetazolamide; Aldosterone; Ascites; Chlorothiazide; Dexamethasone; Diabetes Insipidus; Diuresis; Di

1963
[THE EFFECT OF A SALURETIC-RESERPINE COMBINATION ON EXERTIONAL BLOOD PRESSURE IN MAN].
    Die Medizinische Welt, 1963, Oct-12, Volume: 41

    Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Diuretics; Humans; Hydroflume

1963
[TREATMENT OF HYPERTENSION IN "THERAPY RESISTANT" CASES].
    Die Medizinische Welt, 1964, Jun-27, Volume: 26

    Topics: Antihypertensive Agents; Drug Therapy; Humans; Hydroflumethiazide; Hypertension; Natriuresis; Reserp

1964
HYPOKALEMIA AND HYPERTENSION; A PRESENTATION OF FOUR CASES INCLUDING A CASE OF PRIMARY ALDOSTERONISM.
    Acta medica Scandinavica, 1964, Volume: 176

    Topics: Adrenal Gland Neoplasms; Drug Therapy; Geriatrics; Heart Arrest; Humans; Hydroflumethiazide; Hyperal

1964
[Effect of a new diuretic agent, Furosemide, on the carbohydrate metabolism].
    Nihon Naibunpi Gakkai zasshi, 1966, Mar-20, Volume: 41, Issue:12

    Topics: Blood Glucose; Blood Urea Nitrogen; Carbohydrate Metabolism; Diabetes Mellitus; Furosemide; Glucose

1966
Aldactide and dytide.
    Drug and therapeutics bulletin, 1967, Oct-13, Volume: 5, Issue:21

    Topics: Edema; Humans; Hydroflumethiazide; Hypertension; Spironolactone

1967
HDL-cholesterol, triglycerides and vascular complications in essential hypertension.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 646

    Topics: Adult; Aged; Cardiovascular Diseases; Cholesterol; Female; Humans; Hydroflumethiazide; Hypertension;

1981
Duration of effect of single daily doses of reserpine and hydroflumethiazide evaluated by noninvasive technology in hypertensive patients.
    Cleveland Clinic quarterly, 1982,Winter, Volume: 49, Issue:4

    Topics: Adult; Aged; Blood Pressure; Blood Pressure Determination; Drug Combinations; Drug Evaluation; Femal

1982
[Antihypertensive effects of hydroflumethiazide and prazosin].
    Ugeskrift for laeger, 1980, Jun-09, Volume: 142, Issue:24

    Topics: Adult; Aged; Drug Therapy, Combination; Female; Humans; Hydroflumethiazide; Hypertension; Male; Midd

1980
Parodoxical rise in urinary albumin levels after treatment of essential hypertension.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1997, Volume: 87, Issue:9

    Topics: Adult; Aged; Albuminuria; Antihypertensive Agents; Creatinine; Female; Humans; Hydroflumethiazide; H

1997
[Treatment of severe hypertension with minoxidil combined with beta-blocking agents and diuretics].
    Ugeskrift for laeger, 1975, Dec-29, Volume: 138, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Body Weight; Diuretics; Drug Therapy, Combination; Female;

1975
Long-term experiences with minoxidil in combination treatment of severe arterial hypertension.
    Acta cardiologica, 1977, Volume: 32, Issue:4

    Topics: Adult; Aged; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydroflumethiazide; Hyperte

1977
Hypertension in the elderly: review of therapy with a hydroflumethiazide-reserpine combination.
    Journal of the American Geriatrics Society, 1979, Volume: 27, Issue:11

    Topics: Aged; Blood Pressure; Drug Combinations; Female; Humans; Hydroflumethiazide; Hypertension; Male; Res

1979
Influence of thiazides on thyroid parameters in man.
    Acta endocrinologica, 1978, Volume: 89, Issue:4

    Topics: Adult; Bendroflumethiazide; Diuretics; Female; Humans; Hydrochlorothiazide; Hydroflumethiazide; Hype

1978
Hypotensive effects of pentobarbital and diuretics on sympathectomized spontaneously hypertensive rats.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 226, Issue:1

    Topics: Abdomen; Animals; Blood Pressure; Hydrochlorothiazide; Hydroflumethiazide; Hypertension; Pentobarbit

1977
Beta-adrenergic blockers in the treatment of hypertension--experience with propranolol at Ibadan, Nigeria.
    East African medical journal, 1977, Volume: 54, Issue:4

    Topics: Adult; Aged; Debrisoquin; Drug Therapy, Combination; Female; Humans; Hydroflumethiazide; Hypertensio

1977
Proceedings: Hypertension in SHR after abdominal sympathectomy.
    Japanese heart journal, 1976, Volume: 17, Issue:3

    Topics: Animals; Blood Pressure; Disease Models, Animal; Hydrochlorothiazide; Hydroflumethiazide; Hypertensi

1976
Sodium metabolism in hypertension: Part III. Effects of hypertensive and antihypertensive agents on sodium metabolism in perfused hearts.
    The Kobe journal of medical sciences, 1976, Volume: 22, Issue:2

    Topics: Amiloride; Animals; Epinephrine; Hydroflumethiazide; Hypertension; Metabolism; Myocardium; Norepinep

1976
[Effect of long-term prior antihypertensive treatment on cerebral ischemia induced by bilateral common carotid artery ligation in SHRSR].
    No to shinkei = Brain and nerve, 1986, Volume: 38, Issue:2

    Topics: Adenosine Triphosphate; Animals; Body Water; Brain; Brain Ischemia; Captopril; Carotid Arteries; Cer

1986
[Pharmacological studies on diuretics. 7. Diuretic activity and mechanism of action of a new thiazide diuretic, penfluzide].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:5

    Topics: Adenosine Triphosphatases; Alkalosis; Animals; Antihypertensive Agents; Bendroflumethiazide; Blood P

1973
Serum electrolytes during long term treatment of hypertension with thiazide diuretics in Nigerians.
    The West African medical journal and Nigerian medical & dental practitioner, 1972, Volume: 21, Issue:4

    Topics: Adult; Electrolytes; Female; Humans; Hydroflumethiazide; Hypertension; Male; Middle Aged; Nigeria; T

1972
[A case of acute erythremia occurring during treatment of diabetes and hypertension].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1972, Volume: 13, Issue:6

    Topics: Chlorothiazide; Diabetes Complications; Diabetes Mellitus; Humans; Hydroflumethiazide; Hypertension;

1972
[The antihypertensive effects of bendroflumethiazide, hydroflumethiazide, trichlormethiazide, chlorthalidone and furosemide].
    Ugeskrift for laeger, 1973, Aug-13, Volume: 135, Issue:33

    Topics: Adult; Aged; Bendroflumethiazide; Chlorthalidone; Diuretics; Female; Furosemide; Humans; Hydroflumet

1973
[Diuretics. 5. Effects of single or combined administration of diuretics in normal or spontaneously hypertensive rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:3

    Topics: Acetazolamide; Aminophylline; Animals; Chlorides; Diuretics; Drug Synergism; Hydrochlorothiazide; Hy

1972
Oral thiazide diuretics in the treatment of hypertension in Nigeria.
    The West African medical journal and Nigerian practitioner, 1971, Volume: 20, Issue:5

    Topics: Adult; Blood Pressure; Female; Humans; Hydroflumethiazide; Hypertension; Male; Middle Aged; Time Fac

1971
The long-term treatment of hypertension with thiazide diuretics.
    Postgraduate medical journal, 1971, Volume: 47, Issue:552

    Topics: Antihypertensive Agents; Benzothiadiazines; Diabetes Mellitus; Diuretics; Female; Gout; Humans; Hydr

1971
Thiazide treatment in pregnancy with special reference to maternal and foetal electrolytes.
    Acta obstetricia et gynecologica Scandinavica, 1968, Volume: 47, Issue:4

    Topics: Adolescent; Adult; Blood Chemical Analysis; Chlorides; Diuretics; Edema; Female; Humans; Hydrochloro

1968
[Studies on uric acid metabolism disorders following administration of saluretics].
    Deutsche medizinische Wochenschrift (1946), 1965, Oct-22, Volume: 90, Issue:43

    Topics: Chlorothiazide; Chlorthalidone; Ethacrynic Acid; Furosemide; Humans; Hydrochlorothiazide; Hydroflume

1965
Clinical evaluation of parenteral hydroflumethiazide--as a diuretc and an hypertensive agent.
    The Journal of the Association of Physicians of India, 1965, Volume: 13, Issue:11

    Topics: Adolescent; Adult; Aged; Child; Diuresis; Edema; Female; Humans; Hydroflumethiazide; Hypertension; M

1965