| Assay ID | Title | Year | Journal | Article |
|---|
| AID741609 | Displacement of [125I]-U2 from human recombinant urotensin2 receptor expressed in human Chem-2 cells after 4 hrs by scintillation proximity assay | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Deconstruction of sulfonamide inhibitors of the urotensin receptor (UT) and design and synthesis of benzylamine and benzylsulfone antagonists. |
| AID741608 | Antagonist activity at recombinant human urotensin2 receptor expressed in CHO cells assessed as inhibition of urotensin2-stimulated Ca2+ mobilization after 1 hr by FLIPR assay | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Deconstruction of sulfonamide inhibitors of the urotensin receptor (UT) and design and synthesis of benzylamine and benzylsulfone antagonists. |
| AID349869 | Binding affinity to urotensin-2 receptor | 2009 | Journal of medicinal chemistry, May-14, Volume: 52, Issue:9
| Sequence-derived three-dimensional pharmacophore models for G-protein-coupled receptors and their application in virtual screening. |
| AID445491 | Oral bioavailability in rat | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Nonpeptide urotensin-II receptor antagonists: a new ligand class based on piperazino-phthalimide and piperazino-isoindolinone subunits. |
| AID445493 | Vasorelaxant activity in Wistar rat thoracic aortic ring assessed as inhibition of KCl-induced contraction at 100 nM | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Nonpeptide urotensin-II receptor antagonists: a new ligand class based on piperazino-phthalimide and piperazino-isoindolinone subunits. |
| AID445489 | Antagonist activity at urotensin 2 receptor in human RMS13 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobilization after 1 hr by FLIPR assay | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Nonpeptide urotensin-II receptor antagonists: a new ligand class based on piperazino-phthalimide and piperazino-isoindolinone subunits. |
| AID445488 | Displacement of [125I]urotensin 2 from urotensin 2 receptor in human RMS13 cells by scintillation proximity assay | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Nonpeptide urotensin-II receptor antagonists: a new ligand class based on piperazino-phthalimide and piperazino-isoindolinone subunits. |
| AID485962 | Antagonist activity at rat urotensin 2 receptor expressed in CHO cells assessed as calcium mobilization at 100 nM by FLIPR | 2010 | Journal of medicinal chemistry, Apr-08, Volume: 53, Issue:7
| Urotensin-II receptor modulators as potential drugs. |
| AID445487 | Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobilization after 1 hr by FLIPR assay | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Nonpeptide urotensin-II receptor antagonists: a new ligand class based on piperazino-phthalimide and piperazino-isoindolinone subunits. |
| AID445494 | Inhibition of ear flushing in Sprague-Dawley rat ear-flush model assessed as complete attenuation of urotensin 2-induced increase in ear pinna temperature at 10 mg/kg, iv administered 15 mins prior to urotensin 2 challenge | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Nonpeptide urotensin-II receptor antagonists: a new ligand class based on piperazino-phthalimide and piperazino-isoindolinone subunits. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346323 | Mouse UT receptor (Urotensin receptor) | 2005 | British journal of pharmacology, Jul, Volume: 145, Issue:5
| Nonpeptidic urotensin-II receptor antagonists I: in vitro pharmacological characterization of SB-706375. |
| AID1346351 | Rat UT receptor (Urotensin receptor) | 2005 | British journal of pharmacology, Jul, Volume: 145, Issue:5
| Nonpeptidic urotensin-II receptor antagonists I: in vitro pharmacological characterization of SB-706375. |
| AID1346328 | Human UT receptor (Urotensin receptor) | 2005 | British journal of pharmacology, Jul, Volume: 145, Issue:5
| Nonpeptidic urotensin-II receptor antagonists I: in vitro pharmacological characterization of SB-706375. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |