mazindol has been researched along with Hypertension in 5 studies
Mazindol: Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate, in compliant patients, the pharmaceutical costs of treating obesity with fenfluramine/mazindol, fenfluramine/phentermine, caffeine/ephedrine, or mazindol relative to the pharmaceutical costs of treating obesity-related comorbid conditions and reducing cardiovascular risk." | 3.70 | Pharmaceutical cost savings of treating obesity with weight loss medications. ( Bray, GA; Greenway, FL; Rood, JC; Ryan, DH; Smith, SR; Tucker, EW, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greenway, FL | 1 |
| Ryan, DH | 1 |
| Bray, GA | 1 |
| Rood, JC | 1 |
| Tucker, EW | 1 |
| Smith, SR | 1 |
| Kocemba, J | 1 |
| Kawecka-Jaszcz, K | 1 |
| Miach, PJ | 1 |
| Thomson, W | 1 |
| Doyle, AE | 1 |
| Louis, WJ | 1 |
| Boakes, AJ | 1 |
| Kujirai, K | 1 |
| Przedborski, S | 1 |
| Kostic, V | 1 |
| Jackson-Lewis, V | 1 |
| Fahn, S | 1 |
| Cadet, JL | 1 |
2 trials available for mazindol and Hypertension
| Article | Year |
|---|---|
[Use of mazindol in the dietetic treatment of obesity in patients with essential hypertension].
Topics: Adult; Clinical Trials as Topic; Female; Humans; Hypertension; Indoles; Male; Mazindol; Middle Aged; | 1978 |
Double-blind cross-over evaluation of mazindol in the treatment of obese hypertensive patients.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Hypertension; Indoles; Male; Mazindol; Middle | 1976 |
3 other studies available for mazindol and Hypertension
| Article | Year |
|---|---|
Pharmaceutical cost savings of treating obesity with weight loss medications.
Topics: Adolescent; Adult; Appetite Depressants; Caffeine; Cardiovascular Diseases; Diabetes Mellitus; Drug | 1999 |
Antagonism of bethanidine by mazindol.
Topics: Bethanidine; Blood Pressure; Guanidines; Humans; Hypertension; Indoles; Male; Mazindol; Middle Aged; | 1977 |
Autoradiography of dopamine receptors and dopamine uptake sites in the spontaneously hypertensive rat.
Topics: Animals; Autoradiography; Benzazepines; Brain; Dopamine; Hydroxydopamines; Hypertension; Mazindol; O | 1990 |