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sulpiride and Hypertension

sulpiride has been researched along with Hypertension in 21 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"Plasma prolactin concentrations and prolactinaemic response to sulpiride, a prolactin releaser with pituitary dopamine receptor blocking activity, were examined in 16 subjects with mild essential hypertension and in 20 patients with long-sustained essential hypertension."7.66[Excessive prolactinemic response to sulpiride in patients with mild essential hypertension. Index of diminished hypothalamic dopaminergic activity]. ( Bertolutti, T; Di Chiara, F; Geatti, O; Paladini, G; Sponza, E, 1980)
"Plasma prolactin concentrations and prolactinaemic response to sulpiride, a prolactin releaser with pituitary dopamine receptor blocking activity, were examined in 16 subjects with mild essential hypertension and in 20 patients with long-sustained essential hypertension."3.66[Excessive prolactinemic response to sulpiride in patients with mild essential hypertension. Index of diminished hypothalamic dopaminergic activity]. ( Bertolutti, T; Di Chiara, F; Geatti, O; Paladini, G; Sponza, E, 1980)
"sulpiride."1.27Central and peripheral dopaminergic mechanisms in the cardiovascular actions of pergolide in neurogenic hypertensive dogs. ( Barrett, RJ; Lokhandwala, MF, 1983)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199015 (71.43)18.7374
1990's3 (14.29)18.2507
2000's3 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kruchenko, ZhO1
Henry, A1
Charpiat, B1
Vial, T1
Franchini, S1
Cuilleret, FJ1
Milon, H1
Barrett, RJ3
Lokhandwala, MF2
Paladini, G1
Sponza, E1
Geatti, O1
Di Chiara, F1
Bertolutti, T1
Licata, G1
Scaffidi, A1
Kirouac, GJ1
Ganguly, PK1
Vachvanichsanong, P1
Sela, S1
Sidhu, A1
Lucas-Teixeira, VA1
Vieira-Coelho, MA1
Serrão, P1
Pestana, M1
Soares-da-Silva, P1
Plouin, PF1
Menard, J2
Corvol, P2
Frisina, N1
De Luca, A1
Costa, G1
Buemi, M1
Macrì, I1
Nicita-Mauro, V1
Kinsolving, CR1
Watkins, BE1
Borrelli, AR1
Kaiser, FC1
Wu, ES1
Lucarini, AR1
Arrighi, P1
Favilla, S1
Simonini, N1
Salvetti, A1
Plevová, J1
Sochor, K1
Boleloucký, Z1
Słowińska-Srzednicka, J1
Puciłowska, J1
Zgliczyński, S1
Cavero, I1
Lorrain, J1
Di Paola, ED1
Lhoste, F1
Payen, B1
Dennis, T1
Scatton, B1
Lombardi, C1
De Cotiis, R1
Spedini, C1
Missale, C1
Memo, M1
Spano, PF1
Kau, ST1
Lal, H1
Yaden, S1
Bisseliches, F1
Alexandre, JM1
Bohuon, C1
Heurtault, JP1
Tcherdakoff, P1
Vaysse, JC1
Milliez, P1

Trials

3 trials available for sulpiride and Hypertension

ArticleYear
The influence of dopamine-1 receptor blockade on the humoral and renal effects of low-dose atrial natriuretic factor in human hypertensives.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6

    Topics: Adult; Atrial Natriuretic Factor; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Fem

1989
Reversal by the selective D-2 dopamine receptor blocker sulpiride of the hypotensive effect of co-dergocrine in elderly hypertensives.
    European journal of clinical pharmacology, 1987, Volume: 33, Issue:5

    Topics: Aged; Aged, 80 and over; Clinical Trials as Topic; Dihydroergotoxine; Female; Humans; Hypertension;

1987
[Hypertensive episodes triggered by sulpiride].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1974, Apr-20, Volume: 50, Issue:19

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Catecholamines; Female; Humans; Hypertension; Male; Middle Age

1974

Other Studies

18 other studies available for sulpiride and Hypertension

ArticleYear
[The effect of D2-receptor blockade on the normal and stress-induced activity of the prefrontal cortex neurons in SHR rats].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2009, Volume: 55, Issue:3

    Topics: Action Potentials; Animals; Behavior, Animal; Conditioning, Classical; Dopamine Antagonists; Dopamin

2009
Pheochromocytoma unmasked by amisulpride and tiapride.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:5

    Topics: Adult; Amisulpride; Antipsychotic Agents; Calcium Channel Blockers; Headache; Humans; Hypertension;

2005
Central and peripheral dopaminergic mechanisms in the cardiovascular actions of pergolide in neurogenic hypertensive dogs.
    European journal of pharmacology, 1983, Dec-23, Volume: 96, Issue:3-4

    Topics: Animals; Blood Pressure; Cardiovascular Agents; Cardiovascular System; Central Nervous System; Dogs;

1983
[Excessive prolactinemic response to sulpiride in patients with mild essential hypertension. Index of diminished hypothalamic dopaminergic activity].
    Minerva medica, 1980, Sep-01, Volume: 71, Issue:31

    Topics: Adult; Dopamine; Female; Humans; Hypertension; Hypothalamus; Male; Middle Aged; Prolactin; Renin; Su

1980
Presynaptic dopamine receptor stimulation and the antihypertensive action of pergolide in experimental neurogenic hypertension.
    Proceedings of the Western Pharmacology Society, 1982, Volume: 25

    Topics: Animals; Antihypertensive Agents; Dogs; Electric Stimulation; Ergolines; Female; Hemodynamics; Hyper

1982
[Hypertensive crisis caused by oral administration of sulpiride].
    Minerva cardioangiologica, 1981, Volume: 29, Issue:5

    Topics: Depression; Female; Humans; Hypertension; Middle Aged; Pulmonary Edema; Sulpiride

1981
Up-regulation of dopamine receptors in the brain of the spontaneously hypertensive rat: an autoradiographic analysis.
    Neuroscience, 1993, Volume: 52, Issue:1

    Topics: Animals; Autoradiography; Benzazepines; Blood Pressure; Body Weight; Brain Chemistry; Hypertension;

1993
Absence of DA1/DA2 dopamine receptor interactions in proximal tubules of spontaneously hypertensive rats.
    The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 2

    Topics: Affinity Labels; Animals; Binding Sites; Binding, Competitive; Dopamine Agonists; Dopamine Antagonis

1996
[Amisulpride--a neuroleptic agent for all phases of schizophrenia].
    Der Nervenarzt, 1999, Volume: 70, Issue:3 Suppl Am

    Topics: Amisulpride; Antipsychotic Agents; Chronic Disease; Humans; Hyperkinesis; Hypertension; Risk Factors

1999
Salt intake and sensitivity of intestinal and renal Na+-K+ atpase to inhibition by dopamine in spontaneous hypertensive and Wistar-Kyoto rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2000, Volume: 22, Issue:5

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Diet, Sodium-Restricted; Dopami

2000
Hypertensive crisis in patient with phaeochromocytoma given metoclopramide.
    Lancet (London, England), 1976, Dec-18, Volume: 2, Issue:7999

    Topics: Adrenal Gland Neoplasms; Blood Pressure; Humans; Hypertension; Metoclopramide; Pheochromocytoma; Sul

1976
[Hyperprolactinemia induced with sulpiride in patients with essential arterial hypertension].
    Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:2

    Topics: Adult; Female; Humans; Hypertension; Middle Aged; Prolactin; Renin; Sodium; Sulpiride; Water-Electro

1978
Flavodilol: a new antihypertensive agent.
    Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:1

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Autonomic Nervo

1989
Sulpirid in patients hospitalized in an internal ward.
    Activitas nervosa superior, 1989, Volume: 31, Issue:4

    Topics: Adult; Back Pain; Chlorprothixene; Depression; Female; Hospitalization; Humans; Hypertension; Male;

1989
Arterial hypertension in acromegaly: altered dopaminergic control of aldosterone secretion.
    Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:11

    Topics: Acromegaly; Adrenocorticotropic Hormone; Adult; Aldosterone; Cosyntropin; Female; Humans; Hypertensi

1987
Pharmacological, hemodynamic and biochemical mechanisms involved in the blood pressure lowering effects of pergolide, in normotensive and hypertensive dogs.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Denervation; Dogs; Electric Stimulation; Ergolines;

1985
Myocardial and vascular actions of amiloride in spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2

    Topics: Amiloride; Animals; Atropine; Blood Pressure; Cardiovascular System; Cimetidine; Dose-Response Relat

1986
Discriminative stimuli produced by clonidine in spontaneously hypertensive rats: generalization to antihypertensive drugs with different mechanisms of action.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:1

    Topics: Animals; Antihypertensive Agents; Clonidine; Discrimination Learning; Dose-Response Relationship, Dr

1985