methylmalonic acid has been researched along with Hypertension in 2 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Non-insulin-dependent diabetes mellitus (NIDDM) and hyperhomocysteinemia are both associated with premature vascular disease." | 5.09 | Total homocysteine is associated with nephropathy in non-insulin-dependent diabetes mellitus. ( Allen, RH; Cohen, JA; Estacio, R; Jeffers, BW; Schrier, RW; Stabler, SP, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| He, W | 1 |
| Miao, FJ | 1 |
| Lin, DC | 1 |
| Schwandner, RT | 1 |
| Wang, Z | 1 |
| Gao, J | 1 |
| Chen, JL | 1 |
| Tian, H | 1 |
| Ling, L | 1 |
| Stabler, SP | 1 |
| Estacio, R | 1 |
| Jeffers, BW | 1 |
| Cohen, JA | 1 |
| Allen, RH | 1 |
| Schrier, RW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of a Meat Versus Vegetarian Diet in 12 Healthy Volunteers on the Excretion of Alpha-ketoglutarate Measured in 24-hours Urine[NCT01880281] | 32 participants (Actual) | Interventional | 2013-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for methylmalonic acid and Hypertension
| Article | Year |
|---|---|
Total homocysteine is associated with nephropathy in non-insulin-dependent diabetes mellitus.
Topics: Adult; Aged; Albuminuria; Cystathionine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; | 1999 |
1 other study available for methylmalonic acid and Hypertension
| Article | Year |
|---|---|
Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors.
Topics: Animals; Antihypertensive Agents; Captopril; Cattle; Cell Line; Citric Acid Cycle; Cricetinae; Human | 2004 |