Compounds > ici 118551

ici 118551 and Hypertension

ici 118551 has been researched along with Hypertension in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19907 (38.89)18.7374
1990's9 (50.00)18.2507
2000's2 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Doggrell, SA1
Harada, N; Isobe, H; Okajima, K; Uchiba, M1
Andrén, L; Dahlöf, B; Hansson, L; Svensson, A1
Borkowski, KR; Quinn, P1
Doggrell, SA; Surman, AJ1
de Champlain, J; Drolet, G; Moreau, P; Yamaguchi, N1
de Boer, RE; Kroezen, PA; Smit, J; Steegstra, MR; Zaagsma, J1
Bernstein, D; Chruscinski, AJ; Desai, KH; Kobilka, BK; Rohrer, DK; Schauble, E1
Cerbai, E; Mugelli, A; Pino, R; Rodriguez, ML1
Flügge, G; Nazarali, AJ; Pinto, JE; Saavedra, JM; Torda, T; Viglione, PN1
Keeton, TK1
Hendley, ED; Knardahl, S1
Bühler, FR; Hoyer, D; Jones, CR; Palacios, JM1
Warren, J1
Boomsma, F; Derkx, FH; Man in 't Veld, AJ; Schalekamp, MA; Vincent, HH1
Harry, JD; Petrie, JC; Robb, OJ; Webster, J; Young, J1
Boomsma, F; Derkx, F; Man in 't Veld, AJ; Schalekamp, MA; Vincent, HH1
DiBona, GF; Jones, S; Koepke, JP1

Trials

4 trial(s) available for ici 118551 and Hypertension

ArticleYear
Antihypertensive mechanism of beta-adrenoceptor antagonism--the role of beta 2-blockade.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1983, Volume: 1, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Forearm; Heart Rate; Humans; Hypertension; Middle Aged; Muscles; Propanolamines; Random Allocation; Receptors, Adrenergic, beta; Regional Blood Flow; Vascular Resistance

1983
Is beta 1-antagonism essential for the antihypertensive action of beta-blockers?
    Hypertension (Dallas, Tex. : 1979), 1987, Volume: 9, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertension; Male; Middle Aged; Propanolamines; Propranolol

1987
Effects of the beta 2-adrenoceptor antagonist ICI 118,551 on blood pressure in hypertensive patients known to respond to beta 1-adrenoceptor antagonists.
    British journal of clinical pharmacology, 1988, Volume: 25, Issue:4

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Propanolamines

1988
Compound ICI 118,551, a beta 2-adrenoceptor antagonist, lowers blood pressure.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1985, Volume: 3, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Double-Blind Method; Humans; Hypertension; Isoproterenol; Male; Propanolamines; Propranolol; Renin

1985

Other Studies

14 other study(ies) available for ici 118551 and Hypertension

ArticleYear
Functional beta1- and beta2-adrenoceptors in the left and right atrium of pre-hypertensive rats.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:10

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Bisoprolol; Blood Pressure; Ethanolamines; Heart Atria; Hypertension; Isoproterenol; Male; Myocardium; Procaterol; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2

2002
Activation of capsaicin-sensitive sensory neurons by carvedilol, a nonselective beta-blocker, in spontaneous hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bisoprolol; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Carbazoles; Carvedilol; Cells, Cultured; Drug Interactions; Female; Humans; Hypertension; Kidney; Male; Mice; Neurons, Afferent; Prazosin; Propanolamines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Regional Blood Flow

2004
Adrenaline and the development of genetic hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3

    Topics: Adrenal Medulla; Adrenergic beta-Antagonists; Albuterol; Animals; Blood Pressure; Delayed-Action Preparations; Drug Implants; Epinephrine; Ethanolamines; Hypertension; Mice; Procaterol; Propanolamines; Rats; Rats, Inbred SHR; Time Factors

1984
Functional beta-adrenoceptors in the left atrium of normotensive and hypertensive rats.
    Journal of autonomic pharmacology, 1994, Volume: 14, Issue:6

    Topics: Animals; Atrial Function; Bisoprolol; Calcium Chloride; Ethanolamines; Heart Atria; Hypertension; Isoproterenol; Male; Procaterol; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta

1994
Role of presynaptic beta 2-adrenergic facilitation in the development and maintenance of DOCA-salt hypertension.
    American journal of hypertension, 1993, Volume: 6, Issue:12

    Topics: Adrenalectomy; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Catecholamines; Desoxycorticosterone; Fenoterol; Heart Rate; Hemorrhage; Hydralazine; Hypertension; Male; Nitroprusside; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Receptors, Presynaptic; Sodium Chloride; Sympathetic Nervous System; Synaptic Transmission

1993
Influence of adrenodemedullation on beta 2- and beta 3-adrenoceptors mediating relaxation of oesophageal smooth muscle of spontaneously hypertensive rats.
    British journal of pharmacology, 1996, Volume: 119, Issue:7

    Topics: Adrenal Medulla; Adrenalectomy; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Esophagus; Ethanolamines; Fenoterol; Hypertension; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Propanolamines; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3

1996
Targeted disruption of the beta2 adrenergic receptor gene.
    The Journal of biological chemistry, 1999, Jun-11, Volume: 274, Issue:24

    Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Energy Metabolism; Epinephrine; Gene Targeting; Heart Rate; Hypertension; Iodocyanopindolol; Isoproterenol; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutagenesis; Physical Conditioning, Animal; Propanolamines; Receptors, Adrenergic, beta-2; Respiration; Vasodilation

1999
Modulation of the pacemaker current If by beta-adrenoceptor subtypes in ventricular myocytes isolated from hypertensive and normotensive rats.
    Cardiovascular research, 1999, Volume: 42, Issue:1

    Topics: Action Potentials; Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Cardiomegaly; Catecholamines; GTP-Binding Protein alpha Subunits, Gi-Go; Hypertension; Imidazoles; Isoproterenol; Male; Myocardium; Norepinephrine; Patch-Clamp Techniques; Pertussis Toxin; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Stimulation, Chemical; Virulence Factors, Bordetella

1999
Increased beta 2-adrenoceptors in the superior cervical ganglia of genetically hypertensive rats.
    Brain research, 1991, Feb-22, Volume: 542, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Binding Sites; Binding, Competitive; Enalapril; Ganglia, Sympathetic; Hypertension; Imidazoles; Iodocyanopindolol; Pindolol; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta

1991
Pindolol increases plasma norepinephrine concentration by stimulation of beta 2-adrenoceptors in conscious spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Norepinephrine; Pindolol; Propanolamines; Rats; Rats, Inbred SHR; Receptors, Adrenergic, beta; Renin

1990
Association between cardiovascular reactivity to stress and hypertension or behavior.
    The American journal of physiology, 1990, Volume: 259, Issue:1 Pt 2

    Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Blood Pressure; Captopril; Cardiovascular Physiological Phenomena; Cardiovascular System; Hypertension; Male; Pressoreceptors; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Renin-Angiotensin System; Stress, Physiological; Vascular Resistance; Vasoconstriction; Vasodilation

1990
Receptor modification in the brains of spontaneously hypertensive and Wistar-Kyoto rats: regionally specific and selective increase in cerebellar beta 2-adrenoceptors.
    British journal of clinical pharmacology, 1990, Volume: 30 Suppl 1

    Topics: Animals; Autoradiography; Brain; Cerebellum; Hypertension; Imidazoles; In Vitro Techniques; Iodocyanopindolol; Male; Pindolol; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta

1990
Adrenaline/hypertension hypothesis.
    Lancet (London, England), 1989, Jan-28, Volume: 1, Issue:8631

    Topics: Adrenergic beta-Antagonists; Epinephrine; Humans; Hypertension; Propanolamines

1989
Alpha 2-adrenoceptors in amygdala control renal sympathetic nerve activity and renal function in conscious spontaneously hypertensive rats.
    Brain research, 1987, Feb-24, Volume: 404, Issue:1-2

    Topics: Amygdala; Animals; Blood Pressure; Consciousness; Guanabenz; Hypertension; Kidney; Male; Propanolamines; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha; Stress, Physiological; Sympathetic Nervous System; Yohimbine

1987