Page last updated: 2024-10-21

gallopamil and Hypertension

gallopamil has been researched along with Hypertension in 21 studies

Gallopamil: Coronary vasodilator that is an analog of iproveratril (VERAPAMIL) with one more methoxy group on the benzene ring.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"Systemic and regional hemodynamics were assessed in 10 patients with uncomplicated mild to moderate essential hypertension before and during gallopamil therapy."9.08Systemic and regional hemodynamic effects of gallopamil in patients with essential hypertension. ( Frohlich, ED; Ketelhut, RG; Losem, C; Messerli, FH; Michalewicz, L, 1997)
"In 13 patients, affected by hypertrophic obstructive cardiomyopathy (HOCM) and essential hypertension, antihypertensive-efficacy and effects of a new calcium-channel blocker (gallopamil) associated with a diuretic agent (chlorthalidone) on left ventricular systolic and diastolic performance assessed by phonocardiographic methods."7.67[Gallopamil and chlorthalidone versus atenolol and chlorthalidone in the treatment of obstructive hypertrophic cardiomyopathy in patients with arterial hypertension: polycardiographic evaluation of the systolic and diastolic function of the left ventricle ( Brandini, V; Chieppa, S; De Simone, R; Giuliani, F; Iarussi, D; Langella, S; Lobascio, C, 1989)
"Nitrendipine is a calcium antagonistic 1,4-dihydropyridine derivative with a pronounced antihypertensive activity in animal experiment."5.27Nitrendipine and other calcium entry blockers (calcium antagonists) in hypertension. ( Garthoff, B; Kazda, S; Knorr, A, 1983)
"Systemic and regional hemodynamics were assessed in 10 patients with uncomplicated mild to moderate essential hypertension before and during gallopamil therapy."5.08Systemic and regional hemodynamic effects of gallopamil in patients with essential hypertension. ( Frohlich, ED; Ketelhut, RG; Losem, C; Messerli, FH; Michalewicz, L, 1997)
"In blood pressure (BP) reduction induced by gallopamil, hydralazine and prazosin in patients with essential hypertension a common trend was found in renal prostanoid production which included increased TxB2 excretion and/or augmented TxB2/6-keto-PGF1alfa ratio and, with the exception of response to prazosin, enhanced PGF2alfa excretion."3.68TxA2-PGI2-PGF2 alfa responses in the kidney to blood pressure reduction induced by vasodilator/vasorelaxing agents with different action in patients with essential hypertension. ( Fehér, J; Gachályi, B; Juhász, I; Székács, B, 1993)
"In 13 patients, affected by hypertrophic obstructive cardiomyopathy (HOCM) and essential hypertension, antihypertensive-efficacy and effects of a new calcium-channel blocker (gallopamil) associated with a diuretic agent (chlorthalidone) on left ventricular systolic and diastolic performance assessed by phonocardiographic methods."3.67[Gallopamil and chlorthalidone versus atenolol and chlorthalidone in the treatment of obstructive hypertrophic cardiomyopathy in patients with arterial hypertension: polycardiographic evaluation of the systolic and diastolic function of the left ventricle ( Brandini, V; Chieppa, S; De Simone, R; Giuliani, F; Iarussi, D; Langella, S; Lobascio, C, 1989)
"7 years), with previously untreated essential hypertension and echocardiographically proven left-ventricular hypertrophy, received metoprolol 200 mg daily over a period of 12."3.67[Regression of myocardial hypertrophy in hypertensives on chronic beta-receptor block]. ( Behr, M; Franz, IW; Ketelhut, R; Wiewel, D, 1986)
"Nitrendipine is a calcium antagonistic 1,4-dihydropyridine derivative with a pronounced antihypertensive activity in animal experiment."1.27Nitrendipine and other calcium entry blockers (calcium antagonists) in hypertension. ( Garthoff, B; Kazda, S; Knorr, A, 1983)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199018 (85.71)18.7374
1990's3 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harris, A1
Swamy, VC5
Triggle, DJ5
Waters, DH1
Rutledge, A1
Kazda, S1
Garthoff, B1
Knorr, A1
Nghiem, C2
Pang, CC1
Sutter, MC2
Corbett, DA1
Goldberg, MT2
Triggle, CR2
Székács, B2
Juhász, I2
Gachályi, B1
Fehér, J1
Ketelhut, RG1
Messerli, FH1
Losem, C1
Frohlich, ED1
Michalewicz, L1
Bogoliubov, VM1
Lyskova, MN1
Gribkova, IN1
Kruglova, ZG1
Franz, IW5
Tönnesmann, U3
Behr, U4
Ketelhut, R5
Agrawal, B1
Chieppa, S1
Lobascio, C1
Brandini, V1
Iarussi, D1
Giuliani, F1
Langella, S1
De Simone, R1
Auguet, M1
Delaflotte, S1
Pirotzky, E1
Clostre, F1
Braquet, P1
Wiewel, D1
Behr, M1
Rinaldi, G1
Bohr, D1

Trials

3 trials available for gallopamil and Hypertension

ArticleYear
Systemic and regional hemodynamic effects of gallopamil in patients with essential hypertension.
    Cardiovascular drugs and therapy, 1997, Volume: 11, Issue:1

    Topics: Calcium Channel Blockers; Delayed-Action Preparations; Exercise; Female; Gallopamil; Hemodynamics; H

1997
[Regression of left ventricular hypertrophy in hypertensive patients under long-term therapy with antihypertensive agents].
    Deutsche medizinische Wochenschrift (1946), 1990, Apr-20, Volume: 115, Issue:16

    Topics: Acebutolol; Adult; Antihypertensive Agents; Atenolol; Cardiomegaly; Female; Gallopamil; Humans; Hype

1990
[Regression of left heart hypertrophy in hypertensive patients as a result of antihypertensive therapy].
    Zeitschrift fur Kardiologie, 1989, Volume: 78 Suppl 5

    Topics: Acebutolol; Adult; Antihypertensive Agents; Atenolol; Cardiac Output; Cardiac Volume; Cardiomegaly;

1989

Other Studies

18 other studies available for gallopamil and Hypertension

ArticleYear
Responses to noradrenaline of portal vein strips from normotensive and spontaneously hypertensive rats.
    Journal of autonomic pharmacology, 1980, Volume: 1, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aging; Animals; Blood Pressure; Dioxanes; Gallopamil; Hypertension; In

1980
Calcium-dependence and antagonism of responses to alpha 1- and alpha 2-adrenoceptor agonists in vascular tissues from hypertensive and normotensive rats.
    British journal of pharmacology, 1984, Volume: 83, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Azepines; Blood Pressure; Calcium; Carotid Arte

1984
Nitrendipine and other calcium entry blockers (calcium antagonists) in hypertension.
    Federation proceedings, 1983, Volume: 42, Issue:2

    Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Dogs; Gallopamil; Heart; Hypertension; M

1983
Inhibition by D 600 of norepinephrine- and clonidine-induced responses of the aortae from normotensive (WKY) and spontaneously hypertensive rats (SHR).
    Life sciences, 1982, Jan-04, Volume: 30, Issue:1

    Topics: Animals; Aorta; Calcium Channel Blockers; Clonidine; Gallopamil; Hypertension; In Vitro Techniques;

1982
Inhibition by methoxyverapamil of the responses of smooth muscle from spontaneously hypertensive and normotensive rats.
    Blood vessels, 1982, Volume: 19, Issue:4

    Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Drug Interactions; Gallopamil; Hypertens

1982
Differential effects of D 600 on contractile response of aorta and portal vein from spontaneously hypertensive rats.
    Blood vessels, 1981, Volume: 18, Issue:3

    Topics: Animals; Aorta; Blood Pressure; Calcium; Gallopamil; Hypertension; Muscle Contraction; Portal Vein;

1981
Reactivity of vasa deferentia from spontaneously hypertensive and normotensive Wistar rats.
    Canadian journal of physiology and pharmacology, 1980, Volume: 58, Issue:6

    Topics: Animals; Calcium; Cations; Gallopamil; Hypertension; In Vitro Techniques; Male; Muscle Contraction;

1980
TxA2-PGI2-PGF2 alfa responses in the kidney to blood pressure reduction induced by vasodilator/vasorelaxing agents with different action in patients with essential hypertension.
    Acta physiologica Hungarica, 1993, Volume: 81, Issue:4

    Topics: Adolescent; Adult; Blood Pressure; Dinoprost; Epoprostenol; Female; Gallopamil; Glomerular Filtratio

1993
An analysis of the action of lanthanum on aortic tissue from normotensive and spontaneously hypertensive rats.
    Canadian journal of physiology and pharmacology, 1977, Volume: 55, Issue:5

    Topics: Animals; Aorta, Thoracic; Buffers; Dose-Response Relationship, Drug; Gallopamil; Hydrogen-Ion Concen

1977
[Influence of anti-arrhythmia agents on electrolyte metabolism].
    Kardiologiia, 1976, Volume: 16, Issue:1

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Coronary Disease; Female; Gallopamil; Humans; Hypertension; Mal

1976
Regression of left ventricular hypertrophy from systemic hypertension by gallopamil.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10

    Topics: Adult; Blood Pressure; Cardiomegaly; Echocardiography; Female; Gallopamil; Heart; Humans; Hypertensi

1987
[Gallopamil and chlorthalidone versus atenolol and chlorthalidone in the treatment of obstructive hypertrophic cardiomyopathy in patients with arterial hypertension: polycardiographic evaluation of the systolic and diastolic function of the left ventricle
    Cardiologia (Rome, Italy), 1989, Volume: 34, Issue:8

    Topics: Adult; Aged; Atenolol; Cardiomyopathy, Hypertrophic; Chlorthalidone; Diastole; Drug Evaluation; Drug

1989
Role of endothelium on phenylephrine-triggered contractile events in aorta of spontaneously hypertensive rats.
    Fundamental & clinical pharmacology, 1989, Volume: 3, Issue:6

    Topics: Animals; Aorta, Thoracic; Calcium; Endothelium, Vascular; Gallopamil; Hypertension; Male; Muscle Con

1989
[Regression of myocardial hypertrophy in hypertensives on chronic beta-receptor block].
    Deutsche medizinische Wochenschrift (1946), 1986, Apr-04, Volume: 111, Issue:14

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Cardiomegaly; Carvedilol; Chronic Di

1986
Endothelium-mediated spontaneous response in aortic rings of deoxycorticosterone acetate-hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 13, Issue:3

    Topics: Animals; Aorta, Thoracic; Calcium Chloride; Culture Techniques; Desoxycorticosterone; Dose-Response

1989
Long-term effect of antihypertensive therapy on left ventricular hypertrophy.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1987, Volume: 5, Issue:5

    Topics: Adult; Antihypertensive Agents; Atenolol; Cardiomegaly; Drug Therapy, Combination; Echocardiography;

1987
Ionic permeability and blood pressure.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:4

    Topics: Animals; Aorta; Blood Pressure; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium-Transporting ATPases; Cell Me

1985
Prostanoid response in the kidney of hypertensive subjects as part of renal counteraction to gallopamil-induced blood pressure decrease.
    Acta medica Hungarica, 1988, Volume: 45, Issue:3-4

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Blood Pressure; Dinoprost; Female; Gallopamil; Glomeru

1988