choline has been researched along with Hypertension in 67 studies
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (56.72) | 18.7374 |
| 1990's | 5 (7.46) | 18.2507 |
| 2000's | 8 (11.94) | 29.6817 |
| 2010's | 7 (10.45) | 24.3611 |
| 2020's | 9 (13.43) | 2.80 |
| Authors | Studies |
|---|---|
| Matveeva, MV | 1 |
| Samoilova, YG | 1 |
| Kudlay, DA | 1 |
| He, GD | 1 |
| Liu, XC | 1 |
| Lu, AS | 1 |
| Feng, YQ | 1 |
| Rooney, M | 1 |
| Bottiglieri, T | 1 |
| Wasek-Patterson, B | 1 |
| McMahon, A | 1 |
| Hughes, CF | 1 |
| McCann, A | 1 |
| Horigan, G | 1 |
| Strain, JJ | 1 |
| McNulty, H | 1 |
| Ward, M | 1 |
| Nese, M | 1 |
| Riboli, G | 1 |
| Brighetti, G | 1 |
| Sassi, V | 1 |
| Camela, E | 1 |
| Caselli, G | 1 |
| Sassaroli, S | 1 |
| Borlimi, R | 1 |
| Aucoin, M | 1 |
| Cooley, K | 1 |
| Saunders, PR | 1 |
| Carè, J | 1 |
| Anheyer, D | 1 |
| Medina, DN | 1 |
| Cardozo, V | 1 |
| Remy, D | 1 |
| Hannan, N | 1 |
| Garber, A | 1 |
| Velayos, M | 1 |
| Muñoz-Serrano, AJ | 1 |
| Estefanía-Fernández, K | 1 |
| Sarmiento Caldas, MC | 1 |
| Moratilla Lapeña, L | 1 |
| López-Santamaría, M | 1 |
| López-Gutiérrez, JC | 1 |
| Li, J | 1 |
| Zhang, J | 2 |
| Shen, S | 1 |
| Zhang, B | 2 |
| Yu, WW | 1 |
| Toyoda, H | 1 |
| Huang, DQ | 1 |
| Le, MH | 1 |
| Nguyen, MH | 1 |
| Huang, R | 1 |
| Zhu, L | 1 |
| Wang, J | 6 |
| Xue, L | 1 |
| Liu, L | 4 |
| Yan, X | 2 |
| Huang, S | 1 |
| Li, Y | 7 |
| Xu, T | 2 |
| Li, C | 2 |
| Ji, F | 1 |
| Ming, F | 1 |
| Zhao, Y | 2 |
| Cheng, J | 1 |
| Wang, Y | 4 |
| Zhao, H | 1 |
| Hong, S | 1 |
| Chen, K | 2 |
| Zhao, XA | 1 |
| Zou, L | 1 |
| Sang, D | 1 |
| Shao, H | 1 |
| Guan, X | 1 |
| Chen, X | 2 |
| Chen, Y | 4 |
| Wei, J | 1 |
| Zhu, C | 1 |
| Wu, C | 1 |
| Moore, HB | 1 |
| Barrett, CD | 1 |
| Moore, EE | 1 |
| Jhunjhunwala, R | 1 |
| McIntyre, RC | 1 |
| Moore, PK | 1 |
| Hajizadeh, N | 1 |
| Talmor, DS | 1 |
| Sauaia, A | 1 |
| Yaffe, MB | 1 |
| Liu, C | 3 |
| Lin, Y | 1 |
| Dong, Y | 1 |
| Wu, Y | 1 |
| Bao, Y | 1 |
| Yan, H | 2 |
| Ma, J | 1 |
| Fernández-Cuadros, ME | 1 |
| Albaladejo-Florín, MJ | 1 |
| Álava-Rabasa, S | 1 |
| Usandizaga-Elio, I | 1 |
| Martinez-Quintanilla Jimenez, D | 1 |
| Peña-Lora, D | 1 |
| Neira-Borrajo, I | 1 |
| López-Muñoz, MJ | 1 |
| Rodríguez-de-Cía, J | 1 |
| Pérez-Moro, OS | 1 |
| Abdallah, M | 1 |
| Alsaleh, H | 1 |
| Baradwan, A | 1 |
| Alfawares, R | 1 |
| Alobaid, A | 1 |
| Rasheed, A | 1 |
| Soliman, I | 1 |
| Wendel Garcia, PD | 1 |
| Fumeaux, T | 1 |
| Guerci, P | 1 |
| Heuberger, DM | 1 |
| Montomoli, J | 2 |
| Roche-Campo, F | 1 |
| Schuepbach, RA | 1 |
| Hilty, MP | 1 |
| Poloni, TE | 1 |
| Carlos, AF | 1 |
| Cairati, M | 1 |
| Cutaia, C | 1 |
| Medici, V | 1 |
| Marelli, E | 1 |
| Ferrari, D | 1 |
| Galli, A | 1 |
| Bognetti, P | 1 |
| Davin, A | 1 |
| Cirrincione, A | 1 |
| Ceretti, A | 1 |
| Cereda, C | 1 |
| Ceroni, M | 1 |
| Tronconi, L | 1 |
| Vitali, S | 1 |
| Guaita, A | 1 |
| Leeds, JS | 1 |
| Raviprakash, V | 1 |
| Jacques, T | 1 |
| Scanlon, N | 1 |
| Cundall, J | 1 |
| Leeds, CM | 1 |
| Riva, A | 1 |
| Gray, EH | 1 |
| Azarian, S | 1 |
| Zamalloa, A | 1 |
| McPhail, MJW | 1 |
| Vincent, RP | 1 |
| Williams, R | 1 |
| Chokshi, S | 1 |
| Patel, VC | 1 |
| Edwards, LA | 1 |
| Alqarawi, W | 1 |
| Birnie, DH | 1 |
| Golian, M | 1 |
| Nair, GM | 1 |
| Nery, PB | 1 |
| Klein, A | 1 |
| Davis, DR | 1 |
| Sadek, MM | 1 |
| Neilipovitz, D | 1 |
| Johnson, CB | 1 |
| Green, MS | 1 |
| Redpath, C | 1 |
| Miller, DC | 1 |
| Beamer, P | 1 |
| Billheimer, D | 1 |
| Subbian, V | 1 |
| Sorooshian, A | 1 |
| Campbell, BS | 1 |
| Mosier, JM | 1 |
| Novaretti, JV | 1 |
| Astur, DC | 1 |
| Cavalcante, ELB | 1 |
| Kaleka, CC | 1 |
| Amaro, JT | 1 |
| Cohen, M | 1 |
| Huang, W | 1 |
| Li, T | 1 |
| Ling, Y | 1 |
| Qian, ZP | 1 |
| Zhang, YY | 1 |
| Huang, D | 1 |
| Xu, SB | 1 |
| Liu, XH | 1 |
| Xia, L | 1 |
| Yang, Y | 3 |
| Lu, SH | 1 |
| Lu, HZ | 1 |
| Zhang, R | 2 |
| Ma, JX | 1 |
| Tang, S | 1 |
| Li, CM | 1 |
| Wan, J | 1 |
| Wang, JF | 1 |
| Ma, JQ | 1 |
| Luo, JJ | 1 |
| Chen, HY | 2 |
| Mi, SL | 1 |
| Chen, SY | 1 |
| Su, YG | 1 |
| Ge, JB | 1 |
| Milheiro, SA | 1 |
| Gonçalves, J | 1 |
| Lopes, RMRM | 1 |
| Madureira, M | 1 |
| Lobo, L | 1 |
| Lopes, A | 1 |
| Nogueira, F | 1 |
| Fontinha, D | 1 |
| Prudêncio, M | 1 |
| M Piedade, MF | 1 |
| Pinto, SN | 1 |
| Florindo, PR | 1 |
| Moreira, R | 1 |
| Castillo-Lora, J | 1 |
| Delley, MF | 1 |
| Laga, SM | 1 |
| Mayer, JM | 1 |
| Sutjarit, N | 1 |
| Thongon, N | 1 |
| Weerachayaphorn, J | 1 |
| Piyachaturawat, P | 1 |
| Suksamrarn, A | 1 |
| Suksen, K | 1 |
| Papachristou, DJ | 1 |
| Blair, HC | 1 |
| Hu, Y | 1 |
| Shen, P | 1 |
| Zeng, N | 1 |
| Wang, L | 3 |
| Yan, D | 1 |
| Cui, L | 1 |
| Yang, K | 2 |
| Zhai, C | 1 |
| Yang, M | 1 |
| Lao, X | 1 |
| Sun, J | 1 |
| Ma, N | 1 |
| Wang, S | 2 |
| Ye, W | 1 |
| Guo, P | 1 |
| Rahimi, S | 1 |
| Singh, MP | 1 |
| Gupta, J | 1 |
| Nakanishi, I | 1 |
| Ohkubo, K | 1 |
| Shoji, Y | 1 |
| Fujitaka, Y | 1 |
| Shimoda, K | 1 |
| Matsumoto, KI | 1 |
| Fukuhara, K | 1 |
| Hamada, H | 1 |
| van der Boom, T | 1 |
| Gruppen, EG | 1 |
| Lefrandt, JD | 1 |
| Connelly, MA | 1 |
| Links, TP | 1 |
| Dullaart, RPF | 1 |
| Berry, JD | 1 |
| Bedlack, R | 1 |
| Mathews, D | 1 |
| Agnese, W | 1 |
| Apple, S | 1 |
| Meloncelli, S | 1 |
| Divizia, M | 1 |
| Germani, G | 1 |
| Adefegha, SA | 1 |
| Bottari, NB | 1 |
| Leal, DB | 1 |
| de Andrade, CM | 1 |
| Schetinger, MR | 1 |
| Martínez-Velasco, A | 1 |
| Perez-Ortiz, AC | 1 |
| Antonio-Aguirre, B | 1 |
| Martínez-Villaseñor, L | 1 |
| Lira-Romero, E | 1 |
| Palacio-Pastrana, C | 1 |
| Zenteno, JC | 1 |
| Ramirez, I | 1 |
| Zepeda-Palacio, C | 1 |
| Mendoza-Velásquez, C | 1 |
| Camacho-Ordóñez, A | 1 |
| Ortiz Bibriesca, DM | 1 |
| Estrada-Mena, FJ | 1 |
| Martin, BL | 1 |
| Thompson, LC | 1 |
| Kim, YH | 2 |
| Snow, SJ | 1 |
| Schladweiler, MC | 1 |
| Phillips, P | 1 |
| Harmon, M | 1 |
| King, C | 1 |
| Richards, J | 1 |
| George, I | 1 |
| Haykal-Coates, N | 1 |
| Gilmour, MI | 1 |
| Kodavanti, UP | 1 |
| Hazari, MS | 1 |
| Farraj, AK | 1 |
| Shen, Z | 1 |
| Zou, Y | 1 |
| Gao, K | 1 |
| Lazar, S | 1 |
| Wurtzel, JGT | 1 |
| Ma, P | 1 |
| Goldfinger, LE | 1 |
| Vukelic, M | 1 |
| Laloo, A | 1 |
| Kyttaris, VC | 1 |
| Chen, R | 1 |
| Chen, J | 2 |
| Xun, J | 1 |
| Hu, Z | 1 |
| Huang, Q | 2 |
| Steinhart, C | 1 |
| Shen, Y | 1 |
| Lu, H | 1 |
| Mansuri, A | 1 |
| Lokhande, K | 1 |
| Kore, S | 1 |
| Gaikwad, S | 1 |
| Nawani, N | 1 |
| Swamy, KV | 1 |
| Junnarkar, M | 1 |
| Pawar, S | 1 |
| Shaheen, MY | 1 |
| Basudan, AM | 1 |
| Niazy, AA | 1 |
| van den Beucken, JJJP | 1 |
| Jansen, JA | 1 |
| Alghamdi, HS | 1 |
| Gao, Q | 2 |
| Guo, X | 1 |
| Cao, Y | 1 |
| Jia, X | 1 |
| Xu, S | 1 |
| Lu, C | 2 |
| Zhu, H | 2 |
| Melku, M | 1 |
| Abebe, G | 1 |
| Teketel, A | 1 |
| Asrie, F | 1 |
| Yalew, A | 1 |
| Biadgo, B | 1 |
| Kassa, E | 1 |
| Damtie, D | 1 |
| Anlay, DZ | 1 |
| Ahmed, MFE | 1 |
| Ramadan, H | 1 |
| Seinige, D | 1 |
| Kehrenberg, C | 1 |
| Abd El-Wahab, A | 1 |
| Volkmann, N | 1 |
| Kemper, N | 1 |
| Schulz, J | 1 |
| Hu, MY | 1 |
| Wu, YN | 1 |
| McEvoy, MP | 1 |
| Wang, YF | 1 |
| Cong, WL | 1 |
| Liu, LP | 1 |
| Li, XX | 1 |
| Zhou, CL | 1 |
| Chen, WM | 1 |
| Wei, KL | 1 |
| Tung, SY | 1 |
| Shen, CH | 1 |
| Chang, TS | 1 |
| Yen, CW | 1 |
| Hsieh, YY | 1 |
| Chiu, WN | 1 |
| Hu, JH | 1 |
| Lu, SN | 1 |
| Hung, CH | 1 |
| Alakavuklar, MA | 1 |
| Fuqua, C | 1 |
| Luo, KL | 1 |
| Underwood, RS | 1 |
| Greenwald, I | 1 |
| Elashiry, MM | 1 |
| Elashiry, M | 1 |
| Zeitoun, R | 1 |
| Elsayed, R | 1 |
| Tian, F | 1 |
| Saber, SE | 1 |
| Elashry, SH | 1 |
| Tay, FR | 1 |
| Cutler, CW | 1 |
| O'Dowd, A | 1 |
| Maciel, M | 1 |
| Poole, ST | 1 |
| Jobling, MG | 1 |
| Rollenhagen, JE | 1 |
| Woods, CM | 1 |
| Sincock, SA | 1 |
| McVeigh, AL | 1 |
| Gregory, MJ | 1 |
| Maves, RC | 1 |
| Prouty, MG | 1 |
| Holmes, RK | 1 |
| Savarino, SJ | 1 |
| Mor, MK | 1 |
| Palevsky, PM | 1 |
| Kaufman, JS | 1 |
| Thiessen Philbrook, H | 1 |
| Weisbord, SD | 1 |
| Parikh, CR | 1 |
| John, CM | 1 |
| Phillips, NJ | 1 |
| Jarvis, GA | 1 |
| Zhu, Y | 2 |
| Kilburn, S | 1 |
| Kapoor, M | 1 |
| Chaturvedi, S | 1 |
| Shaw, KJ | 1 |
| Chaturvedi, V | 1 |
| Kong, X | 1 |
| Zhang, T | 1 |
| Xiao, H | 1 |
| Feng, X | 1 |
| Tu, H | 1 |
| Feng, J | 1 |
| Sabet, M | 1 |
| Tarazi, Z | 1 |
| Griffith, DC | 1 |
| Nguyen, F | 1 |
| Guan, P | 1 |
| Guerrero, DT | 1 |
| Kolla, V | 1 |
| Naraparaju, K | 1 |
| Perry, LM | 1 |
| Soberman, D | 1 |
| Pressly, BB | 1 |
| Alferiev, IS | 1 |
| Chorny, M | 1 |
| Brodeur, GM | 1 |
| Gao, X | 2 |
| Cheng, YH | 1 |
| Enten, GA | 1 |
| DeSantis, AJ | 1 |
| Gaponenko, V | 1 |
| Majetschak, M | 1 |
| Kim, DY | 1 |
| Choi, MJ | 1 |
| Ko, TK | 1 |
| Lee, NH | 1 |
| Kim, OH | 1 |
| Cheon, HG | 1 |
| Cai, H | 1 |
| Yip, V | 1 |
| Lee, MV | 1 |
| Wong, S | 1 |
| Saad, O | 1 |
| Ma, S | 1 |
| Ljumanovic, N | 1 |
| Khojasteh, SC | 1 |
| Kamath, AV | 1 |
| Shen, BQ | 1 |
| Cuypers, ML | 1 |
| Chanteux, H | 1 |
| Gillent, E | 1 |
| Bonnaillie, P | 1 |
| Saunders, K | 1 |
| Beckers, C | 1 |
| Delatour, C | 1 |
| Dell'Aiera, S | 1 |
| Ungell, AL | 1 |
| Nicolaï, J | 1 |
| Knapp, AK | 1 |
| Chen, A | 1 |
| Griffin-Nolan, RJ | 1 |
| Baur, LE | 1 |
| Carroll, CJW | 1 |
| Gray, JE | 1 |
| Hoffman, AM | 1 |
| Li, X | 4 |
| Post, AK | 1 |
| Slette, IJ | 1 |
| Collins, SL | 1 |
| Luo, Y | 1 |
| Smith, MD | 1 |
| Temitayo, GI | 1 |
| Olawande, B | 1 |
| Emmanuel, YO | 1 |
| Timothy, AT | 1 |
| Kehinde, O | 1 |
| Susan, LF | 1 |
| Ezra, L | 1 |
| Joseph, OO | 1 |
| Lev, S | 1 |
| Desmarini, D | 1 |
| Liuwantara, D | 1 |
| Sorrell, TC | 1 |
| Hawthorne, WJ | 1 |
| Djordjevic, JT | 1 |
| Verso, MG | 1 |
| Costantino, C | 1 |
| Marrella, A | 1 |
| Immordino, P | 1 |
| Vitale, F | 1 |
| Amodio, E | 1 |
| Wang, YD | 1 |
| Yao, WL | 1 |
| Xin, ZM | 1 |
| Han, TT | 1 |
| Wang, ZG | 1 |
| Chen, L | 1 |
| Cai, C | 1 |
| Zhang, Y | 5 |
| Ba, D | 1 |
| Wen, S | 1 |
| Tian, Q | 1 |
| Lv, W | 1 |
| Cheng, G | 1 |
| Li, N | 1 |
| Yue, XY | 1 |
| Chu, WJ | 1 |
| Chen, Q | 1 |
| Choi, ES | 1 |
| Zhao, X | 3 |
| Zhou, HD | 1 |
| Sun, XF | 1 |
| Sharma, S | 2 |
| Chhoker, S | 1 |
| Xie, C | 1 |
| Ong, EWY | 1 |
| Tan, ZK | 1 |
| Evans, S | 1 |
| Weinheimer, CJ | 1 |
| Kovacs, A | 1 |
| Williams, JW | 1 |
| Randolph, GJ | 1 |
| Jiang, W | 1 |
| Barger, PM | 1 |
| Mann, DL | 1 |
| Liu, J | 3 |
| Huang, Y | 1 |
| Kong, L | 1 |
| Yu, X | 3 |
| Feng, B | 1 |
| Liu, D | 1 |
| Zhao, B | 1 |
| Mendes, GC | 1 |
| Yuan, P | 1 |
| Ge, D | 1 |
| Wang, WM | 1 |
| Fontes, EPB | 1 |
| Li, P | 1 |
| Shan, L | 1 |
| He, P | 1 |
| Katoh, T | 1 |
| Sengoku, T | 1 |
| Hirata, K | 1 |
| Ogata, K | 1 |
| Suga, H | 1 |
| Shun, C | 1 |
| Yong-Yi, J | 1 |
| Mei-Li, C | 1 |
| Shi-Li, L | 1 |
| Jian-Bo, Z | 1 |
| Dan-Li, W | 1 |
| Zhi-Min, G | 1 |
| Ibrahim, AM | 1 |
| Zakhary, SY | 1 |
| Amin, SAW | 1 |
| Ugurlu, M | 1 |
| Fornari, VJ | 1 |
| Hartmann, MSM | 1 |
| Vanni, JR | 1 |
| Rodriguez, R | 1 |
| Langaro, MC | 1 |
| Pelepenko, LE | 1 |
| Zaia, AA | 1 |
| Nakanjako, D | 1 |
| Zalwango, F | 1 |
| Wairagala, P | 1 |
| Luboga, F | 1 |
| Andia Biraro, I | 1 |
| Bukirwa, VD | 1 |
| Mboowa, MG | 1 |
| Cose, S | 1 |
| Seeley, J | 1 |
| Elliott, A | 1 |
| Zhao, G | 1 |
| Sun, P | 1 |
| Hao, S | 1 |
| Wang, X | 1 |
| Qu, G | 1 |
| Xing, Y | 1 |
| Xu, X | 2 |
| Maierhofer, M | 1 |
| Rieger, V | 1 |
| Mayr, T | 1 |
| Liu, Y | 2 |
| Zhang, Q | 1 |
| Bigliardi, AP | 1 |
| Fernandes, CLF | 1 |
| Pinto, EA | 1 |
| Dos Santos, M | 1 |
| Garcia, EM | 1 |
| Baisch, PRM | 1 |
| Soares, MCF | 1 |
| Muccillo-Baisch, AL | 1 |
| da Silva Júnior, FMR | 1 |
| Yu, W | 1 |
| Ju, C | 1 |
| Wang, K | 1 |
| Zheng, Z | 1 |
| Liu, H | 1 |
| Gao, Y | 1 |
| Martínez-Navarro, EM | 1 |
| Cebrián-Tarancón, C | 1 |
| Moratalla-López, N | 1 |
| Lorenzo, C | 1 |
| Alonso, GL | 1 |
| Salinas, RM | 1 |
| Bermúdez de Castro, JM | 1 |
| Modesto-Mata, M | 1 |
| Martín-Francés, L | 1 |
| García-Campos, C | 1 |
| Martínez de Pinillos, M | 1 |
| Martinón-Torres, M | 1 |
| Hasani, M | 1 |
| Wu, F | 2 |
| Warriner, K | 1 |
| Kurz, M | 1 |
| Gretzke, D | 1 |
| Hörlein, R | 1 |
| Turpault, S | 1 |
| Atzrodt, J | 1 |
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| Yao, Y | 1 |
| Ou, X | 1 |
| Zhao, S | 1 |
| Tian, B | 1 |
| Jin, S | 1 |
| Jiang, Z | 1 |
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| Liu, M | 2 |
| Jiang, GD | 1 |
| Mou, LH | 1 |
| Chen, JJ | 1 |
| Li, ZY | 1 |
| He, SG | 1 |
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| Mercadante, R | 1 |
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| Lattimer, TA | 1 |
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| Merenda, MEZ | 1 |
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| Dos Santos, MP | 1 |
| Barion, MRL | 1 |
| Carciofi, AC | 1 |
| de Paula Dorigam, JC | 1 |
| Ribeiro, LB | 1 |
| Vasconcellos, RS | 1 |
| Waller, SB | 1 |
| Peter, CM | 1 |
| Hoffmann, JF | 1 |
| Cleff, MB | 1 |
| Faria de, RO | 1 |
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| Martins, BA | 1 |
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| Jia, Y | 1 |
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| Sangenito, LS | 1 |
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| de Oliveira, D | 1 |
| Junges, A | 1 |
| Cansian, RL | 1 |
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| Klingler, L | 1 |
| Hung, CT | 1 |
| Jeong, SH | 1 |
| Smith, S | 1 |
| Tingle, MD | 1 |
| Wagner Mackenzie, B | 1 |
| Biswas, K | 1 |
| Douglas, RG | 1 |
| Oza, AM | 1 |
| Lorusso, D | 1 |
| Aghajanian, C | 1 |
| Oaknin, A | 1 |
| Dean, A | 1 |
| Colombo, N | 1 |
| Weberpals, JI | 1 |
| Clamp, AR | 1 |
| Scambia, G | 1 |
| Leary, A | 1 |
| Holloway, RW | 1 |
| Gancedo, MA | 1 |
| Fong, PC | 1 |
| Goh, JC | 1 |
| O'Malley, DM | 1 |
| Armstrong, DK | 1 |
| Banerjee, S | 1 |
| García-Donas, J | 1 |
| Swisher, EM | 1 |
| Cella, D | 1 |
| Meunier, J | 1 |
| Goble, S | 1 |
| Cameron, T | 1 |
| Maloney, L | 1 |
| Mörk, AC | 1 |
| Bedel, J | 1 |
| Ledermann, JA | 1 |
| Coleman, RL | 1 |
| Vlek, SL | 1 |
| Burm, R | 1 |
| Govers, TM | 1 |
| Vleugels, MPH | 1 |
| Tuynman, JB | 1 |
| Mijatovic, V | 1 |
| Leicht, AS | 1 |
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| Vaquera, A | 1 |
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| Emory, TH | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Enalapril Maleate and Folic Acid Tablets for Primary Prevention of Stroke in Patients With Hypertension: a Post-marketing, Double-blind, Randomized Controlled Trial.[NCT00794885] | Phase 4 | 20,702 participants (Actual) | Interventional | 2008-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for choline and Hypertension
| Article | Year |
|---|---|
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
TMA/TMAO in Hypertension: Novel Horizons and Potential Therapies.
Topics: Animals; Carnitine; Choline; Gastrointestinal Microbiome; Glucose; Humans; Hypertension; Inflammatio | 2021 |
Mechanisms, regulation and pathologic significance of Mg2+ efflux from erythrocytes.
Topics: Adenosine Triphosphate; Anemia, Sickle Cell; Animals; Antiporters; Chlorides; Choline; Cystic Fibros | 2006 |
Dietary choline: biochemistry, physiology, and pharmacology.
Topics: Animals; Choline; Digestion; Female; Fetus; Food Analysis; Humans; Hypertension; Infant, Newborn; In | 1981 |
A possible connection between an increased concentration of a cytochemically detectable substance in the hypothalamus of the spontaneously hypertensive rat and certain cerebral cholinergic disturbances.
Topics: Acetylcholine; Animals; Choline; Hypertension; Hypothalamus; Rats; Rats, Inbred SHR | 1993 |
[Clinical use of gamma-aminobutyric acid derivatives in experimental and clinical psychiatry and neurology (review of the literature)].
Topics: Aminobutyrates; Animals; Choline; Epilepsy; Humans; Hydroxybutyrates; Hypertension; Hypoxia; Mental | 1971 |
4 trials available for choline and Hypertension
| Article | Year |
|---|---|
Impact of the MTHFR C677T polymorphism on one-carbon metabolites: Evidence from a randomised trial of riboflavin supplementation.
Topics: Amino Acids, Sulfur; Betaine; Choline; Dietary Supplements; Female; Humans; Hypertension; Male; Meth | 2020 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Choline Pathway Nutrients and Metabolites and Cognitive Impairment After Acute Ischemic Stroke.
Topics: Aged; Antihypertensive Agents; Brain Ischemia; China; Choline; Cognition; Cognition Disorders; Cogni | 2021 |
Choline Metabolites, Hydroxybutyrate and HDL after Dietary Fiber Supplementation in Overweight/Obese Hypertensive Women: A Metabolomic Study.
Topics: Adult; Choline; Dietary Fiber; Dietary Supplements; Female; Humans; Hydroxybutyrates; Hypertension; | 2021 |
58 other studies available for choline and Hypertension
| Article | Year |
|---|---|
[Blood pressure variability and neuroplasticity in patients with type 2 diabetes mellitus].
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Choline; Creatine; Diabetes Mellitus, Type 2; | 2022 |
Association of Choline Intake with Blood Pressure and Effects of Its Microbiota-Dependent Metabolite Trimethylamine-N-Oxide on Hypertension.
Topics: Animals; Blood Pressure; Choline; Hypertension; Methylamines; Microbiota; Nutrition Surveys; Oxides; | 2022 |
Circulating choline is associated with coronary artery stenosis in patients with hypertension: A cross-sectional study of Chinese adults.
Topics: Adult; China; Choline; Coronary Stenosis; Cross-Sectional Studies; Humans; Hypertension; Risk Factor | 2020 |
Dietary choline and betaine intake and risk of hypertension development: a 7.4-year follow-up.
Topics: Adult; Betaine; Blood Pressure; Choline; Cohort Studies; Diet; Eating; Female; Follow-Up Studies; Fo | 2021 |
Choline and its metabolites are differently associated with cardiometabolic risk factors, history of cardiovascular disease, and MRI-documented cerebrovascular disease in older adults.
Topics: Aged; Aged, 80 and over; Betaine; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Cere | 2017 |
Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.
Topics: Aged, 80 and over; Aortic Valve Stenosis; Biomarkers; Carnitine; Choline; Diabetes Complications; Fe | 2018 |
Serum Trimethylamine N-Oxide Concentration Is Positively Associated With First Stroke in Hypertensive Patients.
Topics: Aged; Carnitine; Case-Control Studies; China; Choline; Female; Folic Acid; Gastrointestinal Microbio | 2018 |
Regulation of DNA methylation and 2-OG/TET signaling by choline alleviated cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cardiomegaly; Choline; Disease Models, Animal; DNA Methylation; Epigenesis, | 2019 |
Relation of choline intake with blood pressure in the National Health and Nutrition Examination Survey 2007-2010.
Topics: Adult; Aged; Blood Pressure; Choline; Cross-Sectional Studies; Female; Humans; Hypertension; Male; M | 2019 |
Choline ameliorates cardiovascular damage by improving vagal activity and inhibiting the inflammatory response in spontaneously hypertensive rats.
Topics: Animals; Baroreflex; Cardiomegaly; Cardiovascular Diseases; Choline; Cytokines; Disease Models, Anim | 2017 |
N-acetylaspartate/creatine and choline/creatine ratios in the thalami, insular cortex and white matter as markers of hypertension and cognitive impairment in the elderly.
Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Biomarkers; Cerebral Cortex; Choline; Cognition Disor | 2008 |
Intravenous acetylcholine injection in the treatment of hypertension; a contribution from own experiments, their experiences and results.
Topics: Blood Pressure; Blood Pressure Determination; Choline; Humans; Hypertension | 1946 |
Tachycardia, reduced vagal capacity, and age-dependent ventricular dysfunction arising from diminished expression of the presynaptic choline transporter.
Topics: Age Factors; Analysis of Variance; Animals; Autonomic Nervous System; Blotting, Western; Body Weight | 2010 |
Proton magnetic resonance spectroscopy reveals similar white matter biochemical changes in patients with chronic hypertension and early Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Brain; Choline; Chronic Disease; Creatine | 2002 |
Combined uridine and choline administration improves cognitive deficits in spontaneously hypertensive rats.
Topics: Animals; Attention; Blood Pressure; Choline; Cognition; Hypertension; Male; Maze Learning; Rats; Rat | 2003 |
[Choline and liver; extension of the indications for combined choline and levulose therapy in nutritive disorders involving sugar metabolism].
Topics: Acetone; Carbohydrate Metabolism; Choline; Fructose; Humans; Hypertension; Liver Diseases | 1952 |
[Effect of myone and neocatesine on hypertension].
Topics: Choline; Hypertension | 1953 |
[The Doryl high blood pressure test on analysis of hypertension].
Topics: Carbachol; Choline; Humans; Hypertension | 1954 |
[Preliminary clinical study of a new hypotensive drug, nitrocholine].
Topics: Antihypertensive Agents; Choline; Hypertension; Hypotension | 1955 |
[Treatment of hypertension with hypotrite forte].
Topics: Choline; Convallaria; Hypertension | 1955 |
[Therapy of hypertension in medical practice].
Topics: Antihypertensive Agents; Barbiturates; Choline; Humans; Hypertension; Muscle Relaxants, Central; Pla | 1956 |
[Clinical experiences with a new hypotensive preparation: mixture of choline theophyllinate and Rauwolfia serpentina].
Topics: Choline; Humans; Hypertension; Hypotension; Rauwolfia; Secologanin Tryptamine Alkaloids; Theophyllin | 1956 |
Nitrocholine in the treatment of arterial hypertension.
Topics: Choline; Hypertension | 1956 |
Nitrocholine in the treatment of arterial hypertension.
Topics: Choline; Hypertension | 1956 |
Nitrocholine in the treatment of arterial hypertension.
Topics: Choline; Hypertension | 1956 |
Nitrocholine in the treatment of arterial hypertension.
Topics: Choline; Hypertension | 1956 |
[Clinical studies of manganocholine forte].
Topics: Biomedical Research; Choline; Hypertension; Reserpine | 1957 |
Glutamylcholine in the treatment of hypertension.
Topics: Choline; Hypertension | 1957 |
Effect of choline on the hypertension of rats induced by high salt diet.
Topics: Animals; Choline; Diet; Hypertension; Rats; Sodium Chloride; Sodium Chloride, Dietary | 1957 |
Induction of renal hypertension in rats and dogs by potassium or choline deficiency.
Topics: Animals; Choline; Choline Deficiency; Dogs; Hypertension; Hypertension, Renal; Hypokalemia; Potassiu | 1958 |
[Clinical tests of combined Rauwolfia, bromocholine bromide & papaverine hydrochloride in the treatment of arterial hypertension].
Topics: Alkaloids; Antihypertensive Agents; Bromides; Choline; Humans; Hypertension; Hypnotics and Sedatives | 1958 |
Effect of ascorbic acid, riboflavin or choline on the production of hypertension in the rat fed a diet rich in sodium chloride.
Topics: Animals; Ascorbic Acid; Choline; Diet; Hypertension; Rats; Riboflavin; Sodium Chloride; Vitamins | 1958 |
[Hypertension induced by choline deficiency and its reversibility].
Topics: Choline; Choline Deficiency; Hypertension | 1958 |
Electron microscopy in experimental hypertension; glomerular changes in choline-deficiency-induced hypertension in the rat.
Topics: Animals; Choline; Choline Deficiency; Electrons; Hypertension; Kidney; Kidney Diseases; Kidney Glome | 1959 |
Sympathetic nerve blocking drugs for the treatment of hypertension. TM-10, beta TM-10, bretylium and guanethidine.
Topics: Antihypertensive Agents; Bretylium Compounds; Choline; Guanethidine; Hypertension | 1961 |
Factors influencing the hypertensive effect of eserine in the rat.
Topics: Adrenal Glands; Animals; Blood Pressure; Bretylium Compounds; Choline; Epinephrine; Hypertension; No | 1961 |
[The treatment of hypertension with dicolin].
Topics: Choline; Humans; Hypertension; Pipecolic Acids | 1960 |
[Clinical observations on the therapeutic use of choline theophyllinate].
Topics: Choline; Coronary Disease; Heart Failure; Humans; Hypertension; Theophylline | 1959 |
Newer agents which inhibit sympathetic nerve activity.
Topics: Amidines; Autonomic Pathways; Choline; Heart Arrest; Hypertension; Sympathetic Nervous System; Sympa | 1962 |
Production of hypertension following choline deficiency in weanling rats.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Choline; Choline Deficiency; Hypertension; Ra | 1950 |
Effect of renal decapsulation on hypertension induced by single episode of acute choline deficiency.
Topics: Blood Pressure; Blood Pressure Determination; Choline; Choline Deficiency; Humans; Hypertension; Kid | 1951 |
[Symptomatic therapy of high blood pressure].
Topics: Blood Pressure; Choline; Humans; Hypertension | 1951 |
Inhibiting long chain fatty Acyl CoA synthetase increases basal and agonist-stimulated NO synthesis in endothelium.
Topics: Animals; Cells, Cultured; Choline; Coenzyme A Ligases; Coronary Vessels; Cytoplasm; Endothelial Cell | 2004 |
Influence of dietary factors on hypertension induced by choline deficiency.
Topics: Blood Pressure; Blood Pressure Determination; Choline; Choline Deficiency; Humans; Hypertension | 1950 |
Effect of choline deficiency on ACTH production and on hypertension of subtotally nephrectomized rats.
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Blood Pressure Determination; Choline; Choline | 1950 |
Hypertension of renal origin in rats following less than one week of choline deficiency in early life.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Choline; Choline Deficiency; Hypertension; Ki | 1949 |
Diffusion tensor imaging and MR spectroscopy in hypertension and presumed cerebral small vessel disease.
Topics: Aged; Aspartic Acid; Brain Diseases; Brain Ischemia; Case-Control Studies; Cerebrovascular Circulati | 2008 |
A Na+,K+ co-transport assay for essential hypertension.
Topics: Adolescent; Adult; Aged; Biological Transport, Active; Blood Pressure; Cell Membrane Permeability; C | 1980 |
Effect of hemicholinium-3 on the hypothalamic concentration of a cytochemically detectable glucose-6-phosphate dehydrogenase-stimulating substance.
Topics: Acetylcholine; Animals; Blood Pressure; Choline; Enzyme Activation; Glucosephosphate Dehydrogenase; | 1994 |
New approaches in the treatment of hypertensive intracerebral hemorrhage.
Topics: Animals; Brain; Cerebral Hemorrhage; Choline; Dogs; Evoked Potentials; Hematoma; Hemoglobins; Humans | 1993 |
Cholinergic changes in the hippocampus of stroke-prone spontaneously hypertensive rats.
Topics: Acetylcholine; Aging; Animals; Avoidance Learning; Cerebral Cortex; Cerebrovascular Disorders; Choli | 1996 |
Cerebral metabolic impairment in patients with obstructive sleep apnoea: an independent association of obstructive sleep apnoea with white matter change.
Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Body Mass Index; Brain Chemistry; Cerebral Cortex; | 2001 |
Unaltered radial maze performance and brain acetylcholine of the endothelial nitric oxide synthase knockout mouse.
Topics: Acetylcholine; Animals; Anxiety; Brain Chemistry; Choline; Conditioning, Psychological; Hypertension | 2001 |
Glucocorticoid-induced hypertension in rats: role of the central muscarinic cholinergic system.
Topics: Animals; Atropine; Betamethasone; Blood Pressure; Brain; Choline; Hypertension; Male; Rats; Rats, In | 1991 |
On the use of fibroblasts in tissue culture to study the neurochemistry of brain mechanisms controlling blood pressure.
Topics: Animals; Cells, Cultured; Choline; Fibroblasts; Hypertension; Norepinephrine; Rats; Rats, Inbred SHR | 1989 |
Acetylcholine in the posterior hypothalamic nucleus is involved in the elevated blood pressure in the spontaneously hypertensive rat.
Topics: Acetylcholine; Animals; Blood Pressure; Choline; Hemicholinium 3; Hypertension; Hypothalamus; Inject | 1989 |
[Use of citicoline in the study of chronic cerebrovascular diseases].
Topics: Adrenergic beta-Antagonists; Aged; Choline; Chronic Disease; Cytidine Diphosphate Choline; Diuretics | 1988 |
The antihypertensive effect of ethylcholine aziridinium (AF64A), a cholinergic neurotoxin, in spontaneously hypertensive rats, following administration into the posterior hypothalamus.
Topics: Animals; Aziridines; Azirines; Blood Pressure; Choline; Heart Rate; Hypertension; Hypothalamus; Hypo | 1988 |
Changes in regional brain synaptosomal high affinity choline uptake during the development of hypertension in spontaneously hypertensive rats.
Topics: Animals; Brain; Choline; Corpus Striatum; Hybridization, Genetic; Hypertension; Hypothalamus; Male; | 1987 |
[Therapy of arteriosclerosis].
Topics: Anticholesteremic Agents; Anticoagulants; Arteriosclerosis; Cholesterol; Choline; Diabetes Complicat | 1968 |
Hypertension in young rats following choline deficiency in maternal diets.
Topics: Age Factors; Aging; Animals; Blood Pressure Determination; Choline; Choline Deficiency; Female; Feta | 1971 |