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salicylsalicylic acid and Hypertension

salicylsalicylic acid has been researched along with Hypertension in 2 studies

salicylsalicylic acid: structure
salsalate : A dimeric benzoate ester obtained by intermolecular condensation between the carboxy of one molecule of salicylic acid with the phenol group of a second. It is a prodrug for salycylic acid that is used for treatment of rheumatoid arthritis and osteoarthritis and also shows activity against type II diabetes.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"Salsalate regulated inflammation by affecting the expression of genes from MAPK signalling and NOD-like receptor signalling pathways and lipid metabolism by affecting hepatic expression of genes that favour lipid oxidation from PPAR-α signalling pathways."1.46Salsalate ameliorates metabolic disturbances by reducing inflammation in spontaneously hypertensive rats expressing human C-reactive protein and by activating brown adipose tissue in nontransgenic controls. ( Haluzík, M; Kazdová, L; Kuda, O; Landa, V; Mlejnek, P; Oliyarnyk, O; Pravenec, M; Šilhavý, J; Šimáková, M; Škop, V; Strnad, H; Trnovská, J; Zídek, V, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Trnovská, J1
Šilhavý, J1
Kuda, O1
Landa, V1
Zídek, V1
Mlejnek, P1
Šimáková, M1
Strnad, H1
Škop, V1
Oliyarnyk, O1
Kazdová, L1
Haluzík, M1
Pravenec, M1
Phillips, BB1
Joss, JD1
Mulhausen, PL1

Other Studies

2 other studies available for salicylsalicylic acid and Hypertension

ArticleYear
Salsalate ameliorates metabolic disturbances by reducing inflammation in spontaneously hypertensive rats expressing human C-reactive protein and by activating brown adipose tissue in nontransgenic controls.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Adipose Tissue, Brown; Animals; Animals, Genetically Modified; C-Reactive Protein; Fatty Acids, None

2017
Blood pressure elevation in a patient treated with salsalate.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:4

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Humans; Hypertension; Low Back Pain; Male; Salicylate

2002