Page last updated: 2024-08-17

lysine and Hypertension

lysine has been researched along with Hypertension in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-199019 (27.54)18.7374
1990's2 (2.90)18.2507
2000's28 (40.58)29.6817
2010's12 (17.39)24.3611
2020's8 (11.59)2.80

Authors

AuthorsStudies
Gholami, SK; Heydarpour, M; Hopkins, PN; Luther, JM; Parksook, WW; Pojoga, LH; Williams, JS1
Jonniya, NA; Kar, P; Roy, R; Sk, MF1
Benton, HP; Benzing, T; Bleich, M; Cravatt, BF; Demir, F; Dissanayake, LV; Domingo-Almenara, X; El-Meanawy, A; Gliozzi, ML; Golosova, D; Guijas, C; Himmerkus, N; Hoehne, M; Jaegers, J; Kok, BP; Krüger, M; Palermo, A; Palygin, O; Rinschen, MM; Saez, E; Schafroth, MA; Siuzdak, G; Staruschenko, A; Weisz, OA; Xue, J1
Bai, BL; Li, YQ; Lin, Y; Ma, LJ; Shi, L; Wang, H; Wu, HJ; Zhang, Q; Zou, JZ1
Cao, N; Chen, C; Chen, Y; Gong, X; Hu, C; Jose, PA; Lan, C; Li, Z; Luo, H; Qu, S; Ren, H; Wu, G; Xu, Z; Yang, J; Yu, C; Yu, J; Zeng, C; Zheng, S1
Brooks, DL; Huang, Y; Pojoga, LH; Romero, JR; Tan, YJD; Williams, JS; Wong, KYH1
De Becker, B; Van De Borne, P1
Bai, C; Chen, J; Feng, Y; Ge, J; Li, H; Liu, T; Ping, J; Song, L; Sun, Y; Wang, X; Xiao, N; Xu, H; Zhang, M1
Castañeda-Bueno, M; Cornelius, RJ; Ellison, DH; Erspamer, KJ; Ferdaus, MZ; Gamba, G; McCormick, JA; Miller, LN; Su, XT; Terker, AS; Wang, WH; Yang, CL1
Böhm, M; Ewen, S; Hohl, M; Kazakov, A; Kindermann, I; Laufs, U; Linz, D; Mahfoud, F; Selejan, SR; Speer, T; Tatu, AM; Zamyatkin, O1
Agostoni, P; Aldini, G; Banfi, C; Brioschi, M; Gianazza, E; Martinez Fernandez, A; Regazzoni, L1
Akcali, KC; Ayaloglu-Butun, F; Demirel-Yilmaz, E; Han, S; Uludag, MO; Usanmaz, SE1
Ferrucci, L; Garcia, M; Harris, TB; Newman, AB; Satterfield, S; Schwartz, AV; Semba, RD; Sun, K; Varadhan, R1
Galar, B; Jakim, P; Jasiewicz, M; Kaminski, KA; Lisowska, A; Marcinkiewicz-Siemion, M; Miklasz, P; Musial, WJ; Ptaszynska-Kopczynska, K; Waszkiewicz, E; Witkowski, M1
Aliani, M; Hanson, M; Taylor, CG; Zahradka, P1
Kruger, R; Mokwatsi, GG; Schutte, AE1
Meyer, DM; Mills, LD; Mohammed, SF; Owan, TE; Redfield, MM; Schalkwijk, CG; Shapiro, BP1
Baum, L; Chan, JC; Chan, WM; Chan, YM; Choy, KW; Fan, BJ; Fung, NS; Lam, DS; Li, H; Liu, DT; Louey, JW; Pang, CP1
Hartog, JW; Voors, AA; Willemsen, S1
Baumann, M; Eckstein, HH; Heemann, U; Kouznetsova, T; Pelisek, J; Richart, T; Roos, M; Sollinger, D; Staessen, JA1
Hartog, JW; Jaarsma, W; Miyata, T; Plokker, HW; Schalkwijk, CG; Smit, AJ; van de Wal, RM; van Veldhuisen, DJ; van Wijk, LM; Voors, AA1
Engelen, L; Ferreira, I; Hovind, P; Parving, HH; Persson, F; Rossing, P; Schalkwijk, CG; Stehouwer, CD; Teerlink, T1
Evans, RG; Hanchapola, I; Kaye, DM; Kuruppu, S; Mattson, DL; Rajapakse, NW; Smith, AI; Venardos, K1
Ben Yahia, S; Bouzidi, H; Hammami, M; Kerkeni, M; Letaief, A; Saïdi, A1
Alderson, NL; Baynes, JW; Beattie, RJ; Chachich, ME; Nachtigal, M; Thorpe, SR; Youssef, NN1
Ding, Q; Dong, LY; Lu, JY; Sun, ZJ; Wang, XN; Zhao, YY1
Bulut, D; Hanefeld, C; Koll, R; Liaghat, S; Miebach, T; Mügge, A1
Baliga, S; Cai, W; Goldberg, T; Lu, M; Peppa, M; Uribarri, J; Vassalotti, JA; Vlassara, H1
MOSES, A1
BUEHLMANN, A; HAEMMERLI, UP; TSAKIRIS, A1
Barker, DJ; Eriksson, JG; Forsen, T; Kubaszek, A; Laakso, M; Markkanen, A; Osmond, C1
Kamide, K; Kawano, Y; Miyata, T; Takiuchi, S; Tanaka, C1
Abe, M; Hisano, S; Horiuchi, S; Iwasaki, H; Nangaku, M; Sakata, N; Uesugi, N1
Antipina, VV; Makarova, ER; Minushkina, LO; Nosikov, VV; Petrova, IR; Romanova, TA; Sidorenko, BA; Zateĭshikov, DA1
Brown, NJ; Dai, D; David, GL; Gainer, JV; Goldstein, JA; King, LM; Zeldin, DC1
Aizawa, T; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Nangaku, M; Tominaga, N; van Ypersele de Strihou, C1
Shamloul, R; Wang, R1
de Champlain, J; Desai, K; Juurlink, BH; Wang, X; Wu, L1
Katayama, S1
Brandstädt, A; Busch, M; Franke, S; Gerth, J; Hunsicker, LG; Ott, U; Stein, G; Wolf, G1
Durante, A; Monacelli, F; Odetti, P; Poggi, A; Storace, D; Traverso, N; Viviani, GL1
Ahmad, TS; Kuppusamy, UR; Mahmood, AA; Nazratun, N; Tan, SY1
Chen, HI; Chuang, IC; Kao, SJ; Liu, YC1
Izuhara, Y; Miyata, T; Nangaku, M; Ohtomo, S; Strihou, Cv; Takizawa, S1
Baumann, M; Heemann, U; Schalkwijk, C; Scheijen, J; Stehouwer, C; Struijker Boudier, H1
Chang, T; Desai, K; Jia, X; Wang, X; Wu, L1
Busch, M; Franke, S; Rohde, RD; Stein, G; Wolf, G1
Chen, HI; Hsu, BG; Hsu, YH1
Mahoney, DW; Olson, TM; Redfield, MM; Reyes, S; Rodeheffer, RJ; Terzic, A1
Furukawa, Y; Ito, M; Nozaki, O; Takada, M; Yamaguchi, M1
Karppanen, H; Laakso, J; Malmberg, L; Mervaala, EM; Teräväinen, TL; Vapaatalo, H1
Fan, W; Horiuchi, K; Kouda, K; Nakamura, H; Takeuchi, H1
Horie, R; Ohta, K; Sato, M; Yamori, Y1
Cardinale, GJ; Iwatsuki, K; Spector, S; Udenfriend, S1
Georgiev, P; Iurukova, Ts1
Georgiev, PG; Jurukova, ZB1
Lovenberg, W; Nakada, T1
Horie, R; Ikeda, K; Nara, Y; Ohtake, M; Yamori, Y1
Lovenberg, W; Nakada, T; Yamori, Y1
Oratz, M; Rothschild, MA; Schreiber, SS1
Harano, K; Harano, T; Imai, K; Ohkushi, T; Ueda, S1
Kondo, M1
Bartolini, G; Bastagli, L; Bernardi, P; Cavazza, M; Danieli, A; Fontana, F; Minelli, C; Orlandi, M; Tommasi, V; Ventura, C1
Kadar, A; Robert, B; Robert, L1
Lovenberg, W; Yamabe, H1
Laborit, H; Valette, N1
Maidanik, FE; Savenko, SN; Vladkovskiĭ, IK1
Lindblad, BS1
Bános, C; Borbély, L; Fisher, J; Radó, JP; Szende, L; Takó, J1

Reviews

2 review(s) available for lysine and Hypertension

ArticleYear
[Oxidative stress marker].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Arginine; Biomarkers; Deoxyguanosine; Dinoprost; Glycation End Products, Advanced; Humans; Hypertension; Lipid Peroxides; Lipoproteins, LDL; Lysine; Oxidative Stress

2006
The macromolecules of the intercellular matrix of the arterial wall: collagen, elastin, proteoglycans, and glycoproteins.
    Advances in experimental medicine and biology, 1974, Volume: 43, Issue:0

    Topics: Age Factors; Aging; Animals; Aorta; Arteries; Arteriosclerosis; Carbon Radioisotopes; Chickens; Collagen; Connective Tissue; Connective Tissue Cells; Elastin; Endothelium; Female; Glycoproteins; Glycosaminoglycans; Humans; Hydroxyproline; Hypertension; In Vitro Techniques; Lysine; Male; Microscopy, Electron; Muscle, Smooth; Proline; Rabbits; Rats; Swine

1974

Trials

4 trial(s) available for lysine and Hypertension

ArticleYear
Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction.
    European journal of heart failure, 2010, Volume: 12, Issue:4

    Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diastole; Female; Glycation End Products, Advanced; Humans; Hypertension; Imidazoles; Linear Models; Lysine; Male; Middle Aged; Multivariate Analysis; Netherlands; Skin; Statistics as Topic; Statistics, Nonparametric; Stroke Volume; Thiophenes; Ventricular Function, Left

2010
Irbesartan treatment does not influence plasma levels of the advanced glycation end products N(epsilon)(1-carboxymethyl)lysine and N(epsilon)(1-carboxyethyl)lysine in patients with type 2 diabetes and microalbuminuria. A randomized controlled trial.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:11

    Topics: Adult; Aged; Albuminuria; Angiotensin Receptor Antagonists; Biomarkers; Biphenyl Compounds; Diabetes Complications; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glycation End Products, Advanced; Humans; Hypertension; Irbesartan; Lysine; Male; Middle Aged; Prognosis; Tetrazoles

2011
Selective cyclo-oxygenase-2 inhibition with parecoxib acutely impairs endothelium-dependent vasodilatation in patients with essential hypertension.
    Journal of hypertension, 2003, Volume: 21, Issue:9

    Topics: Acetylcholine; Adult; Aged; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Forearm; Humans; Hypertension; Isoenzymes; Isoxazoles; Lysine; Male; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; Regional Blood Flow; Vasodilation; Vasodilator Agents

2003
Serum levels of the advanced glycation end products Nepsilon-carboxymethyllysine and pentosidine are not influenced by treatment with the angiotensin receptor II type 1 blocker irbesartan in patients with type 2 diabetic nephropathy and hypertension.
    Nephron. Clinical practice, 2008, Volume: 108, Issue:4

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arginine; Biphenyl Compounds; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Hypertension; Irbesartan; Linear Models; Lysine; Male; Middle Aged; Statistics, Nonparametric; Tetrazoles

2008

Other Studies

63 other study(ies) available for lysine and Hypertension

ArticleYear
Salt Sensitivity of Blood Pressure and Aldosterone: Interaction Between the Lysine-specific Demethylase 1 Gene, Sex, and Age.
    The Journal of clinical endocrinology and metabolism, 2022, 04-19, Volume: 107, Issue:5

    Topics: Aldosterone; Animals; Blood Pressure; Epigenesis, Genetic; Estrogens; Female; Histone Demethylases; Humans; Hypertension; Lysine; Mice; Mice, Knockout; Sodium Chloride, Dietary

2022
Discovery of potential competitive inhibitors against With-No-Lysine kinase 1 for treating hypertension by virtual screening, inverse pharmacophore-based lead optimization, and molecular dynamics simulations.
    SAR and QSAR in environmental research, 2022, Volume: 33, Issue:2

    Topics: High-Throughput Screening Assays; Humans; Hypertension; Lysine; Molecular Docking Simulation; Molecular Dynamics Simulation; Quantitative Structure-Activity Relationship

2022
Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension.
    Nature communications, 2022, 07-14, Volume: 13, Issue:1

    Topics: Albumins; Animals; Carbon; Disease Models, Animal; Hypertension; Kidney; Lysine; Malonyl Coenzyme A; Rats

2022
Increasing angiotensin-converting enzyme 1 regulated by histone 3 lysine 27 hyperacetylation in high-fat diet-induced hypertensive rat kidney.
    Journal of hypertension, 2022, 10-01, Volume: 40, Issue:10

    Topics: Angiotensins; Animals; Blood Pressure; Diet, High-Fat; Histones; Hypertension; Kidney; Lysine; Male; Obesity; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System

2022
Prenatal Lipopolysaccharides Exposure Induces Transgenerational Inheritance of Hypertension.
    Circulation, 2022, 10-04, Volume: 146, Issue:14

    Topics: Animals; Cyclic N-Oxides; Female; Histone Demethylases; Histones; Hypertension; Jumonji Domain-Containing Histone Demethylases; Lipopolysaccharides; Lysine; Pregnancy; Prenatal Exposure Delayed Effects; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Mineralocorticoid; Spin Labels; Spironolactone

2022
Lysine-specific demethylase 1 deficiency modifies aldosterone synthesis in a sex-specific manner.
    The Journal of endocrinology, 2023, Jan-01, Volume: 256, Issue:1

    Topics: Aldosterone; Animals; Blood Pressure; Female; Hypertension; Lysine; Male; Mice; Zona Glomerulosa

2023
Serum uric acid: a futile bystander in endothelial function?
    Blood pressure, 2023, Volume: 32, Issue:1

    Topics: Adult; Allantoin; Angiotensin II; Blood Pressure; Humans; Hypertension; Lysine; Male; Microcirculation; Pulse Wave Analysis; Uric Acid; Vascular Stiffness

2023
Identification of circular RNA expression profiles and potential biomarkers for intracerebral hemorrhage.
    Epigenomics, 2021, Volume: 13, Issue:5

    Topics: Biomarkers; Cerebral Hemorrhage; Female; Humans; Hypertension; Integrins; Lysine; Male; MicroRNAs; Middle Aged; RNA, Circular; RNA, Messenger

2021
With no lysine kinase 4 modulates sodium potassium 2 chloride cotransporter activity in vivo.
    American journal of physiology. Renal physiology, 2018, 10-01, Volume: 315, Issue:4

    Topics: Animals; Chlorides; Hypertension; Kidney Tubules, Collecting; Kidney Tubules, Distal; Lysine; Mice, Knockout; Potassium; Protein Serine-Threonine Kinases; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1

2018
Sympathoadrenergic suppression improves heart function by upregulating the ratio of sRAGE/RAGE in hypertension with metabolic syndrome.
    Journal of molecular and cellular cardiology, 2018, Volume: 122

    Topics: ADAM10 Protein; Analysis of Variance; Animals; Denervation; Disease Models, Animal; Fibroblasts; HMGB1 Protein; Hypertension; Kidney; Leukocytes, Mononuclear; Ligands; Lysine; Male; Metabolic Syndrome; Myocardium; Obesity; Protein Isoforms; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Adrenergic, beta; Statistics, Nonparametric; Sympathetic Nervous System; Up-Regulation

2018
Pro-oxidant and pro-inflammatory effects of glycated albumin on cardiomyocytes.
    Free radical biology & medicine, 2019, 11-20, Volume: 144

    Topics: Aged; Case-Control Studies; Cell Death; Cell Line; Dyslipidemias; Female; Gene Expression Profiling; Gene Ontology; Glycated Serum Albumin; Glycation End Products, Advanced; Glycosylation; Heart Failure; HSP90 Heat-Shock Proteins; Humans; Hypertension; Interleukin-6; Lysine; Male; Middle Aged; Molecular Sequence Annotation; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, Brain; Protein Carbonylation; Protein Processing, Post-Translational; Reactive Oxygen Species; Serum Albumin; Serum Albumin, Human; Tumor Necrosis Factor-alpha

2019
Resveratrol affects histone 3 lysine 27 methylation of vessels and blood biomarkers in DOCA salt-induced hypertension.
    Molecular biology reports, 2015, Volume: 42, Issue:1

    Topics: Animals; Antioxidants; Arginine; Biomarkers; Blood Pressure; Blood Vessels; Desoxycorticosterone Acetate; Endothelium, Vascular; Fluorescent Antibody Technique; Histones; Hydrogen Sulfide; Hypertension; Lysine; Male; Methylation; Nitrites; Rats, Wistar; Renal Artery; Resveratrol; Stilbenes; Systole; Vasodilation

2015
Serum carboxymethyl-lysine, an advanced glycation end product, is associated with arterial stiffness in older adults.
    Journal of hypertension, 2015, Volume: 33, Issue:4

    Topics: Aged; Aging; Aorta; Body Composition; Cardiovascular Diseases; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Hypertension; Inflammation; Linear Models; Lipoproteins, HDL; Logistic Models; Lysine; Male; Odds Ratio; Pulse Wave Analysis; Smoking; Vascular Stiffness

2015
Alterations of soluble TWEAK and CD163 concentrations in patients with chronic heart failure.
    Cytokine, 2016, Volume: 80

    Topics: Adult; Aged; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aspirin; Case-Control Studies; Cytokine TWEAK; Down-Regulation; Female; Heart Failure; Humans; Hypertension; Inflammation; Leukocyte Count; Lysine; Male; Middle Aged; Multivariate Analysis; Receptors, Cell Surface; Risk Factors; Tumor Necrosis Factors

2016
Identification of urinary metabolites with potential blood pressure-lowering effects in lentil-fed spontaneously hypertensive rats.
    European journal of nutrition, 2018, Volume: 57, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Citrulline; Diet; Hypertension; Lens Plant; Lysine; Male; Metabolomics; Pyridoxamine; Rats; Rats, Inbred SHR; Seeds

2018
Ethnic differences regarding arterial stiffness of 6-8-year-old black and white boys.
    Journal of hypertension, 2017, Volume: 35, Issue:5

    Topics: Arginine; Arteries; Black People; Body Composition; Body Mass Index; Body Weight; Carotid Arteries; Carotid Intima-Media Thickness; Child; Compliance; Glycation End Products, Advanced; Humans; Hypertension; Lysine; Male; Pulse Wave Analysis; Vascular Stiffness; Waist Circumference; White People

2017
Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines.
    Circulation, 2008, Sep-02, Volume: 118, Issue:10

    Topics: Aging; Animals; Aorta; Collagen; Dogs; Drug Evaluation, Preclinical; Elastin; Glycation End Products, Advanced; Heart Ventricles; Hypertension; Lysine; Muscle, Smooth, Vascular; Thiazoles; Vasa Vasorum; Vascular Resistance; Ventricular Function, Left

2008
EDN1 Lys198Asn is associated with diabetic retinopathy in type 2 diabetes.
    Molecular vision, 2008, Sep-15, Volume: 14

    Topics: Age of Onset; Aged; Asparagine; Case-Control Studies; China; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Endothelin-1; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; Lysine; Male; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Regression Analysis

2008
Letter by Hartog et al. regarding article, "Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines".
    Circulation, 2009, Mar-17, Volume: 119, Issue:10

    Topics: Animals; Arginine; Collagen; Cross-Linking Reagents; Dogs; Glycation End Products, Advanced; Hypertension; Lysine; Muscle, Smooth, Vascular; Thiazoles

2009
Association between carotid diameter and the advanced glycation end product N-epsilon-carboxymethyllysine (CML).
    Cardiovascular diabetology, 2009, Aug-06, Volume: 8

    Topics: Adult; alpha-2-HS-Glycoprotein; Anthropometry; Belgium; Biomarkers; Blood Proteins; Carotid Arteries; Carotid Artery Diseases; Cohort Studies; Elasticity; Female; Glycation End Products, Advanced; Humans; Hypertension; Inflammation; Lysine; Male; Mechanotransduction, Cellular; Middle Aged; Sampling Studies; Tunica Intima; Ultrasonography

2009
Evidence that renal arginine transport is impaired in spontaneously hypertensive rats.
    American journal of physiology. Renal physiology, 2012, Jun-15, Volume: 302, Issue:12

    Topics: Animals; Arginine; Biological Transport; Hemodynamics; Hypertension; Kidney; Lysine; Male; Nitric Oxide; Nitroprusside; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Renal Circulation

2012
Pentosidine as a biomarker for microvascular complications in type 2 diabetic patients.
    Diabetes & vascular disease research, 2013, Volume: 10, Issue:3

    Topics: Aged; Arginine; Biomarkers; Cohort Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Glycation End Products, Advanced; Humans; Hyperlipidemias; Hypertension; Lysine; Male; Microvessels; Middle Aged; Prospective Studies; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Severity of Illness Index; Up-Regulation

2013
The AGE inhibitor pyridoxamine inhibits lipemia and development of renal and vascular disease in Zucker obese rats.
    Kidney international, 2003, Volume: 63, Issue:6

    Topics: Animals; Aorta; Arginine; Blood Glucose; Blood Pressure; Collagen; Female; Glycation End Products, Advanced; Hyperlipidemias; Hypertension; Kidney; Kidney Diseases; Lysine; Pyridoxamine; Rats; Rats, Zucker; Skin; Weight Gain

2003
[Correlation analysis between WNK4 gene and essential hypertension].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2003, Volume: 25, Issue:2

    Topics: Adult; Brain; Female; Gene Expression; Gene Frequency; Genes; Genetic Predisposition to Disease; Humans; Hypertension; Kidney; Lysine; Male; Middle Aged; Mutation; Phenotype; Protein Serine-Threonine Kinases; RNA, Messenger

2003
Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:3

    Topics: Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus; Diet; Diet Records; Food Analysis; Food Handling; Glycation End Products, Advanced; Humans; Hypertension; Kidney Failure, Chronic; Lysine; Metabolic Clearance Rate; New York City; Peritoneal Dialysis; Pyruvaldehyde; Renal Dialysis; Smoking; Surveys and Questionnaires; Uremia

2003
DIABETES INSIPIDUS.
    Medical science, 1964, Volume: 15

    Topics: Arginine Vasopressin; Diabetes Insipidus; Diabetes Insipidus, Neurogenic; Humans; Hypertension; Lysine; Obesity; Vasopressins

1964
REDUCTION OF PORTAL VENOUS PRESSURE IN CIRRHOTIC PATIENTS WITH BLEEDING FROM OESOPHAGEAL VARICES, BY ADMINISTRATION OF A VASOPRESSIN DERIVATIVE, PHENYLALANINE-2-LYSINE-8-VASOPRESSIN.
    The American journal of medicine, 1964, Volume: 36

    Topics: Adolescent; Biomedical Research; Blood Pressure; Cardiac Catheterization; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Geriatrics; Humans; Hypertension; Hypertension, Portal; Infusions, Parenteral; Liver Circulation; Liver Cirrhosis; Lysine; Pharmacology; Phenylalanine; Portal Pressure; Portal Vein; Toxicology; Vasopressins

1964
The association of the K121Q polymorphism of the plasma cell glycoprotein-1 gene with type 2 diabetes and hypertension depends on size at birth.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:5

    Topics: Aged; Alleles; Birth Weight; Diabetes Mellitus, Type 2; Female; Glutamine; Humans; Hypertension; Lysine; Male; Phosphoric Diester Hydrolases; Plasma Cells; Polymorphism, Genetic; Pyrophosphatases

2004
Evaluation of the Lys198Asn and -134delA genetic polymorphisms of the endothelin-1 gene.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:5

    Topics: 5' Untranslated Regions; Adenine; Aged; Amino Acid Substitution; Animals; Asparagine; Cells, Cultured; COS Cells; Culture Media; Endothelin-1; Female; Gene Deletion; Gene Expression; Humans; Hypertension; Lysine; Male; Middle Aged; Polymorphism, Single Nucleotide

2004
Possible mechanism for medial smooth muscle cell injury in diabetic nephropathy: glycoxidation-mediated local complement activation.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2004, Volume: 44, Issue:2

    Topics: Acrolein; Adult; Aged; Aged, 80 and over; Arteriosclerosis; Complement Activation; Complement Membrane Attack Complex; Diabetic Nephropathies; Female; Glomerulosclerosis, Focal Segmental; Glycation End Products, Advanced; Humans; Hypertension; Kidney; Kidney Glomerulus; Lysine; Male; Middle Aged; Models, Biological; Nephrosclerosis; Oxidation-Reduction; Tunica Media

2004
[Angiotensin converting enzyme, NO-synthase, and endothelin-1 genes and left ventricular hypertrophy in natives of Yakutia with hypertensive disease].
    Kardiologiia, 2005, Volume: 45, Issue:1

    Topics: Adult; Alanine; Asparagine; Blood Flow Velocity; Endothelin-1; Female; Gene Frequency; Genotype; Glycine; Humans; Hypertension; Hypertrophy, Left Ventricular; Lysine; Male; Middle Aged; Mitral Valve; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Genetic; Russia; Severity of Illness Index

2005
Single nucleotide polymorphisms in the CYP2J2 and CYP2C8 genes and the risk of hypertension.
    Pharmacogenetics and genomics, 2005, Volume: 15, Issue:1

    Topics: Adult; Alleles; Arginine; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Electrolytes; Female; Genotype; Humans; Hypertension; Linkage Disequilibrium; Lysine; Male; Middle Aged; Odds Ratio; Oxygenases; Pharmacogenetics; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Risk; Sex Factors

2005
Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:12

    Topics: Analysis of Variance; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biopsy, Needle; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Hypertension, Renal; Immunohistochemistry; In Vitro Techniques; Kidney; Lysine; Male; Rats; Rats, Inbred SHR; Sensitivity and Specificity; Statistics, Nonparametric

2005
Monitoring circulatory heme level in hemin therapy for lowering blood pressure in rats.
    Cellular and molecular biology (Noisy-le-Grand, France), 2005, Oct-03, Volume: 51, Issue:5

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Heme; Hemin; Hypertension; Lysine; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley

2005
Gender-related differences in advanced glycation endproducts, oxidative stress markers and nitric oxide synthases in rats.
    Kidney international, 2006, Volume: 69, Issue:2

    Topics: Animals; Female; Glycation End Products, Advanced; Hypertension; Immunohistochemistry; Kidney; Lysine; Male; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Sex Characteristics; Transcription Factor RelA

2006
The advanced glycation end product N(epsilon)-carboxymethyllysine is not a predictor of cardiovascular events and renal outcomes in patients with type 2 diabetic kidney disease and hypertension.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 48, Issue:4

    Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Disease Progression; Female; Glycation End Products, Advanced; Humans; Hypertension; Lysine; Male; Middle Aged; Multivariate Analysis; Oxidative Stress; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Risk Factors

2006
Effects of valsartan therapy on protein glycoxidation.
    Metabolism: clinical and experimental, 2006, Volume: 55, Issue:12

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Arginine; Dinoprost; Female; Glycation End Products, Advanced; Glycosylation; Humans; Hypertension; Lysine; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Proteins; Tetrazoles; Valine; Valsartan

2006
Diabetes mellitus exacerbates advanced glycation end product accumulation in the veins of end-stage renal failure patients.
    Vascular medicine (London, England), 2006, Volume: 11, Issue:4

    Topics: Adult; Aged; Arginine; Brachiocephalic Veins; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Hypertension; Immunohistochemistry; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Radial Artery

2006
Nitric oxide modulates air embolism-induced lung injury in rats with normotension and hypertension.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:11

    Topics: Animals; Blood Pressure; Capillary Permeability; Cyclic GMP; Disease Models, Animal; Embolism, Air; Enzyme Inhibitors; Hypertension; Interleukin-1beta; Lung; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitroprusside; Organ Size; Perfusion; Proteins; Pulmonary Artery; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Respiratory Distress Syndrome; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha

2007
Cobalt ameliorates renal injury in an obese, hypertensive type 2 diabetes rat model.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:4

    Topics: Animals; Antimutagenic Agents; Arginine; Basic Helix-Loop-Helix Transcription Factors; Blood Pressure; Blotting, Western; Chromatography, High Pressure Liquid; Cobalt; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Gene Expression; Glycation End Products, Advanced; Hypertension; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immediate-Early Proteins; Insulin-Like Growth Factor Binding Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Lysine; Male; NADPH Oxidases; Obesity; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Inbred SHR; RNA, Messenger; Transforming Growth Factor beta

2008
N epsilon-(carboxymethyl)lysine during the early development of hypertension.
    Annals of the New York Academy of Sciences, 2008, Volume: 1126

    Topics: Albuminuria; Animals; Blood Pressure; Creatinine; Glycation End Products, Advanced; Heart Rate; Humans; Hypertension; Lysine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2008
Attenuation of hypertension development by scavenging methylglyoxal in fructose-treated rats.
    Journal of hypertension, 2008, Volume: 26, Issue:4

    Topics: Animals; Aorta; Dietary Carbohydrates; Fructose; Glutathione; Glycation End Products, Advanced; Hydrogen Peroxide; Hypertension; Hypoglycemic Agents; Lysine; Male; Mesenteric Arteries; Metformin; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Pyruvaldehyde; Rats; Rats, Sprague-Dawley

2008
Malignant alterations following early blockade of nitric oxide synthase in hypertensive rats.
    The Chinese journal of physiology, 2007, Dec-31, Volume: 50, Issue:6

    Topics: Animals; Blood Pressure; Blood Urea Nitrogen; Body Weight; Endothelin-1; Enzyme Inhibitors; Glomerular Filtration Rate; Hypertension; Isothiuronium; Kidney; Kidney Function Tests; Lysine; Muscle Weakness; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Nitroarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Ventricular Function, Left

2007
K(ATP) channel polymorphism is associated with left ventricular size in hypertensive individuals: a large-scale community-based study.
    Human genetics, 2008, Volume: 123, Issue:6

    Topics: Aged; Cohort Studies; Cross-Sectional Studies; Female; Heart Ventricles; Humans; Hypertension; Lysine; Male; Middle Aged; Organ Size; Polymorphism, Single Nucleotide; Potassium Channels, Inwardly Rectifying; Ventricular Remodeling

2008
Preparation of corn peptide from corn gluten meal and its administration effect on alcohol metabolism in stroke-prone spontaneously hypertensive rats.
    Journal of nutritional science and vitaminology, 1996, Volume: 42, Issue:3

    Topics: Acetaldehyde; Alanine; Amino Acids; Animals; Bacillus; Cerebrovascular Disorders; Chromatography, Gel; Endopeptidases; Ethanol; Glutens; Hypertension; Lysine; Male; Molecular Weight; Peptides; Rats; Rats, Inbred SHR; Zea mays

1996
Influence of dietary salts on the cardiovascular effects of low-dose combination of ramipril and felodipine in spontaneously hypertensive rats.
    British journal of pharmacology, 1998, Volume: 123, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Cardiovascular System; Drug Interactions; Felodipine; Heart Rate; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; Insulin; Kidney; Lysine; Magnesium Chloride; Male; Mesenteric Arteries; Muscle Relaxation; Potassium Chloride; Ramipril; Rats; Rats, Inbred SHR; Sodium, Dietary

1998
The relationship of oxidative DNA damage marker 8-hydroxydeoxyguanosine and glycoxidative damage marker pentosidine.
    Clinical biochemistry, 2001, Volume: 34, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Arginine; Deoxyguanosine; DNA Damage; Female; Glycation End Products, Advanced; Humans; Hypercholesterolemia; Hypertension; Lysine; Male; Middle Aged; Oxidative Stress

2001
Proceedings: Hypophyseal function in SHR: lysine incorporation and ACTH content.
    Japanese heart journal, 1976, Volume: 17, Issue:3

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Disease Models, Animal; Hypertension; Lysine; Pituitary Gland; Rats

1976
Reduction of blood pressure and vascular collagen in hypertensive rats by beta-aminopropionitrile.
    Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:1

    Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Aorta; Blood Pressure; Collagen; Desoxycorticosterone; Hypertension; Lysine; Male; Rats; Solubility

1977
[Arterial scleroproteins in atherosclerosis and hypertension (experimental studies)].
    Eksperimentalna meditsina i morfologiia, 1979, Volume: 18, Issue:1

    Topics: Animals; Aorta; Arteriosclerosis; Collagen; Elastin; Hypertension; Hypertension, Renal; Lysine; Proline; Protein Biosynthesis; Rats; Rats, Inbred Strains

1979
Increased arterial and elastin biosynthesis in experimental atherosclerosis and hypertension.
    Comptes rendus de l'Academie Bulgare des sciences : sciences mathematiques et naturelles, 1977, Volume: 30, Issue:11

    Topics: Animals; Aorta; Arteriosclerosis; Diet, Atherogenic; Elastin; Hypertension; Lysine; Rats; Rats, Inbred Strains; Time Factors

1977
Lysine incorporation in vessels of spontaneously hypertensive rats: effects of adrenergic drugs.
    European journal of pharmacology, 1978, Mar-01, Volume: 48, Issue:1

    Topics: Animals; Arteries; Blood Pressure; Blood Vessels; Collagen; Elastin; Hypertension; Lysine; Phenoxybenzamine; Propranolol; Protein Biosynthesis; Rats; Rats, Inbred Strains; Sympathomimetics

1978
Prophylactic trials for stroke in stroke-prone SHR (2). Effects of fat, protein and amino acids [proceedings].
    Japanese heart journal, 1977, Volume: 18, Issue:4

    Topics: Animals; Blood Pressure; Cerebrovascular Disorders; Cholesterol, Dietary; Diet; Dietary Fats; Dietary Proteins; Hypertension; Lysine; Proline; Rats; Vitamin E

1977
Effect of antihypertensive therapy on lysine incorporation into vascular protein of the spontaneously hypertensive rat.
    European journal of pharmacology, 1976, Volume: 38, Issue:2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Blood Vessels; Collagen; Denervation; Elastin; Hypertension; Lysine; Male; Mesenteric Arteries; Organ Size; Protein Biosynthesis; Rats; Splanchnic Nerves; Time Factors

1976
Pressure versus flow stress: the response of cardiac protein synthesis.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 8

    Topics: Adenosine Triphosphate; Animals; Cardiac Volume; Guinea Pigs; Heart Atria; Heart Diseases; Heart Ventricles; Hypertension; Hypoxia; Lysine; Male; Models, Biological; Muscle Proteins; Myocardial Contraction; Myocardium; Perfusion; Phenylalanine; Pressure; Stress, Physiological

1975
A new hemoglobin variant, Hb Mito [beta 144(HC 1) Lys----Glu], with increased oxygen affinity.
    FEBS letters, 1985, Nov-11, Volume: 192, Issue:1

    Topics: Amino Acid Sequence; Electrophoresis, Cellulose Acetate; Female; Glutamates; Glutamic Acid; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Hypertension; Isoelectric Focusing; Japan; Lysine; Middle Aged; Oxygen

1985
Autoradiographic study of 3H-lysine uptake by superior cervical and stellate ganglia in prehypertensive spontaneously hypertensive rats.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1986, Volume: 52, Issue:4

    Topics: Animals; Animals, Newborn; Autoradiography; Biological Transport, Active; Ganglia, Sympathetic; Hypertension; Lysine; Male; Nerve Tissue Proteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1986
Clinical trial with muzolimine in healthy and hypertensive subjects: new vistas on the drug action.
    International journal of clinical pharmacology research, 1987, Volume: 7, Issue:6

    Topics: Aged; Aspirin; Dinoprostone; Drug Therapy, Combination; Humans; Hypertension; Lysine; Middle Aged; Muzolimine; Prostaglandins E; Pyrazoles

1987
Increased incorporation of 14C-lysine into vascular proteins of the spontaneously hypertensive rat.
    European journal of pharmacology, 1974, Volume: 29, Issue:1

    Topics: Actomyosin; Aging; Animals; Aorta; Blood Pressure; Blood Proteins; Body Weight; Carbon Radioisotopes; Elastin; Hypertension; Kinetics; Liver; Lysine; Male; Myocardium; Organ Size; Rats; Rats, Inbred Strains; Time Factors

1974
[The action of arachidonic acid on experimental arterial hypertension in the rat].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1973, Volume: 14, Issue:6

    Topics: Animals; Arachidonic Acids; Aspirin; Blood Pressure; Corticosterone; Drug Antagonism; Hypertension; Lysine; Male; Nephrectomy; Oxidation-Reduction; Rats; Sodium Chloride

1973
[The serum amino acid spectrum of hypertensive patients with cerebral circulatory disorders].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1971, Volume: 71, Issue:9

    Topics: Adult; Aged; Alanine; Amino Acids; Arginine; Aspartic Acid; Cerebrovascular Disorders; Female; Humans; Hypertension; Lysine; Male; Middle Aged; Tyrosine

1971
The venous plasma free amino acid levels during the first hours of life. I. After normal and short gestation and gestation complicated by hypertension, with special reference to the "small for dates" syndrome.
    Acta paediatrica Scandinavica, 1970, Volume: 59, Issue:1

    Topics: Alanine; Amino Acids; Arginine; Birth Weight; Blood Glucose; Body Height; Chromatography, Ion Exchange; Female; Gestational Age; Glycine; Growth; Growth Disorders; Humans; Hypertension; Infant, Newborn; Infant, Premature; Isoleucine; Leucine; Lysine; Ornithine; Polythiazide; Pregnancy; Pregnancy Complications, Cardiovascular; Protein Deficiency; Time Factors; Valine; Veins

1970
Different effects of frusemide administered during hypertonic saline infusion in healthy subjects and hypertensive patients.
    Clinical science, 1970, Volume: 39, Issue:6

    Topics: Adult; Biological Transport; Depression, Chemical; Diuretics; Female; Furosemide; Humans; Hypertension; Hypertonic Solutions; Kidney; Kidney Concentrating Ability; Lysine; Male; Middle Aged; Sodium; Sodium Chloride; Urine; Vasopressins; Water

1970