clorgyline has been researched along with Hypertension in 8 studies
Clorgyline: An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
clorgyline : An aromatic ether that is the 2,4-dichlorophenyl ether of 3-aminopropan-1-ol in which the nitrogen is substituted by a methyl group and a prop-1-yn-3-yl group. A monoamine oxidase inhibitor, it was formerly used as an antidepressant.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with clorgyline (2 mg/kg p." | 1.38 | Cardiovascular baroreceptor activity and selective inhibition of monoamine oxidase. ( Bar-Am, O; Finberg, JP; Friedman, R; Gross, A, 2012) |
| "Treatment with clorgyline (1 mg kg-1, i." | 1.29 | Acceleration by chronic treatment with clorgyline of the turnover of brain alpha 2-adrenoceptors in normotensive but not in spontaneously hypertensive rats. ( García-Sevilla, JA; Miralles, A; Ribas, C, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bar-Am, O | 1 |
| Gross, A | 1 |
| Friedman, R | 1 |
| Finberg, JP | 1 |
| Zemishlany, Z | 1 |
| Radwan, M | 1 |
| Wijsenbeek, H | 1 |
| Sandler, M | 1 |
| Glover, V | 1 |
| Ashford, A | 1 |
| Esmail, A | 1 |
| Youdim, MB | 1 |
| Gleiter, CH | 1 |
| Mühlbauer, B | 1 |
| Schulz, RM | 1 |
| Nilsson, E | 1 |
| Antonin, KH | 1 |
| Bieck, PR | 1 |
| Ribas, C | 1 |
| Miralles, A | 1 |
| García-Sevilla, JA | 1 |
| Anderson, MC | 1 |
| Hasan, F | 1 |
| McCrodden, JM | 1 |
| Tipton, KF | 1 |
| Senjo, M | 1 |
| Yamazaki, N | 1 |
| Minami, M | 1 |
| Hirokami, M | 1 |
| Saito, H | 1 |
| Parvez, H | 1 |
2 reviews available for clorgyline and Hypertension
| Article | Year |
|---|---|
Monoamine oxidase inhibitors--current status.
Topics: Antidepressive Agents, Tricyclic; Brain Chemistry; Catecholamines; Chemical Phenomena; Chemistry; Cl | 1983 |
The advent of selective monoamine oxidase A inhibitor antidepressants devoid of the cheese reaction.
Topics: Benzamides; Cheese; Clorgyline; Depressive Disorder; Humans; Hypertension; Moclobemide; Monoamine Ox | 1995 |
6 other studies available for clorgyline and Hypertension
| Article | Year |
|---|---|
Cardiovascular baroreceptor activity and selective inhibition of monoamine oxidase.
Topics: Animals; Baroreflex; Blood Pressure; Cardiovascular System; Clorgyline; Dose-Response Relationship, | 2012 |
The inhibition of tyramine oxidation and the tyramine hypertensive response ("cheese effect") may be independent phenomena.
Topics: Animals; Blood Pressure; Clorgyline; Hypertension; Liver; Male; Monoamine Oxidase; Phenethylamines; | 1980 |
Monoamine oxidase inhibition by the MAO-A inhibitors brofaromine and clorgyline in healthy volunteers.
Topics: Administration, Oral; Adult; Blood Pressure; Clorgyline; Cross-Over Studies; Dose-Response Relations | 1994 |
Acceleration by chronic treatment with clorgyline of the turnover of brain alpha 2-adrenoceptors in normotensive but not in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain Chemistry; Brimonidine Tartr | 1993 |
Monoamine oxidase inhibitors and the cheese effect.
Topics: Animals; Biological Transport; Cheese; Clorgyline; Diet; Drug Interactions; Humans; Hypertension; In | 1993 |
Decreased monoamine oxidase activity in stroke-prone spontaneously hypertensive rat kidneys.
Topics: Animals; Cerebrovascular Disorders; Clorgyline; Hypertension; In Vitro Techniques; Kidney; Mitochond | 1986 |