n-(2-acetamido)-2-aminoethanesulfonic acid profile

Also known as N-Acetylglucosamine-6-sulphate, this compound is a derivative of glucosamine. It is a building block for the synthesis of various glycosaminoglycans, which are important components of cartilage and other connective tissues. The compound is also involved in various biological processes, including cell signaling and inflammation. Studies have shown that it can potentially be used in the treatment of osteoarthritis and other joint diseases. The compound is synthesized by reacting glucosamine with acetic anhydride and sulfuryl chloride.'

N-(2-acetamido)-2-aminoethanesulfonic acid : A Good's buffer substance, pKa = 6.9 at 20 degreeC. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID Source	ID
PubMed CID	81832
CHEBI ID	39060
SCHEMBL ID	99940
MeSH ID	M0083385

Synonyms (53)

Synonym
ai3-62515
unii-i5spl5yvby
nsc 166668
i5spl5yvby ,
ethanesulfonic acid, 2-((2-amino-2-oxoethyl)amino)-
einecs 230-908-4
{2-[(2-amino-2-oxoethyl)amino]ethanesulfonic} acid
ethanesulfonic acid, {2-[(2-amino-2-oxoethyl)amino]-}
2-[(2-amino-2-oxo-ethyl)amino]ethanesulfonic acid
2-((2-amino-2-oxoethyl)amino)ethanesulfonic acid
7365-82-4
ethanesulfonic acid, 2-[(2-amino-2-oxoethyl)amino]-
nsc-166668
nsc166668
2-[(2-amino-2-oxoethyl)amino]ethanesulfonic acid
ACES ,
aces, bioxtra, >=99.0% (titration)
aces, bioperformance certified, >=99.0%
aces, >=99.0% (titration)
n-(2-acetamido)-2-aminoethanesulfonic acid
CHEBI:39060
n-(carbamoylmethyl)taurine
2-[(carbamoylmethyl)amino]ethanesulfonic acid
A0700
n-[2-acetamido]-2-aminoethanesulfonic acid
A837887
c4h10n2o4s
FT-0629094
AKOS015892697
aces [mi]
taurine, n-(carbamoylmethyl)-
2-(carbamoylmethylamino)ethanesulfonic acid
SCHEMBL99940
(n-(-2-acetamido))-2-aminoethanesulfonic acid
DTXSID8064644
W-104447
n-(carbamoylmethyl)-2-aminoethanesulfonic acid
mfcd00008030
2-[(carbamoylmethyl)amino]ethane-1-sulfonic acid
aces, bioultra, >=99.5% (t)
AS-67685
HY-D0866
CS-0015175
aces, vetec(tm) reagent grade, 98%
aces, anhydrous, free-flowing, redi-dri(tm), >=99.0%
SY018218
F20338
n-(2-acetamido)-2-aminoethanesulphonic acid
Q10859796
2-(2-amino-2-oxoethylamino)ethanesulfonic acid
luq ,
n-(2-acetamido)-2-aminoethanesulfonic acid [good's buffer component for biological research]
n-(carbamoylmethyl)-2-aminoethanesulfonicacid

Class	Description
ACES
amino sulfonic acid	An organosulfonic acid containing one or more amino groups.
ACES
1,1-diunsubstituted alkanesulfonate	An alkanesulfonate in which the carbon at position 1 is attached to at least two hydrogens.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	4 (23.53)	18.7374
1990's	1 (5.88)	18.2507
2000's	1 (5.88)	29.6817
2010's	3 (17.65)	24.3611
2020's	8 (47.06)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (5.56%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	1 (5.56%)	0.25%
Other	16 (88.89%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
nickel Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.. nickel ion : A nickel atom having a net electric charge.. nickel atom : Chemical element (nickel group element atom) with atomic number 28.	6.95	1	metal allergen; nickel group element atom	epitope; micronutrient
taurine [no description available]	5.33	17	amino sulfonic acid; zwitterion	antioxidant; Escherichia coli metabolite; glycine receptor agonist; human metabolite; mouse metabolite; nutrient; radical scavenger; Saccharomyces cerevisiae metabolite
1-anilino-8-naphthalenesulfonate 1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd. 8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.	2.02	1	aminonaphthalene; naphthalenesulfonic acid	fluorescent probe
indapamide Indapamide: A benzamide-sulfonamide-indole derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.. indapamide : A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.	2.31	1	indoles; organochlorine compound; sulfonamide	antihypertensive agent; diuretic
glycylglycine [no description available]	2.02	1	dipeptide zwitterion; dipeptide	human metabolite
docusate Dioctyl Sulfosuccinic Acid: All-purpose surfactant, wetting agent, and solubilizer used in the drug, cosmetics, and food industries. It has also been used in laxatives and as cerumenolytics. It is usually administered as either the calcium, potassium, or sodium salt.	2.02	1	diester; organosulfonic acid
4-nitrophenyl acetate [no description available]	2.02	1	C-nitro compound; phenyl acetates
dithiothreitol 1,4-dimercaptobutane-2,3-diol : A glycol that is butane-2,3-diol in which a hydrogen from each of the methyl groups is replaced by a thiol group.. 1,4-dithiothreitol : The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol.	1.97	1	1,4-dimercaptobutane-2,3-diol; butanediols; dithiol; glycol; thiol	chelator; human metabolite; reducing agent
manganese Manganese: A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035). manganese(4+) : A manganese cation that is monoatomic and has a formal charge of +4.	6.95	1	elemental manganese; manganese group element atom	Escherichia coli metabolite; micronutrient
silver Silver: An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.	1.97	1	copper group element atom; elemental silver	Escherichia coli metabolite
pyranine pyranine: structure	2.02	1	organic sodium salt	fluorochrome
morpholinopropane sulfonic acid 3-(N-morpholino)propanesulfonic acid : A Good's buffer substance, pKa = 7.2 at 20 degreeC.	1.98	1	MOPS; morpholines; organosulfonic acid
cobalt Cobalt: A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.. cobalt(1+) : A monovalent inorganic cation obtained from cobalt.. cobalt atom : A cobalt group element atom that has atomic number 27.	6.95	1	cobalt group element atom; metal allergen	micronutrient
perindopril Perindopril: An angiotensin-converting enzyme inhibitor. It is used in patients with hypertension and heart failure.. perindopril : An alpha-amino acid ester that is the ethyl ester of N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvaline	2.31	1	alpha-amino acid ester; dicarboxylic acid monoester; ethyl ester; organic heterobicyclic compound	antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
alpha-chymotrypsin Chymotrypsin: A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side.	2.02	1
nitrophenols Nitrophenols: PHENOLS carrying nitro group substituents.	2.02	1

Condition	Relationship Strength	Studies
Blood Pressure, High [description not available]	2.76	2
Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.	2.76	2
Atherogenesis [description not available]	2.41	1
Breast Cancer [description not available]	2.41	1
Arteriosclerosis, Coronary [description not available]	2.41	1
Breast Neoplasms Tumors or cancer of the human BREAST.	2.41	1
Coronary Artery Disease Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.	2.41	1
Atherosclerosis A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.	2.41	1
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	3.33	1
Behavior Disorders [description not available]	2.41	1
Mental Disorders Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.	2.41	1
Affective Disorders [description not available]	2.25	1
Affective Psychosis, Bipolar [description not available]	2.25	1
Bipolar Disorder A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.	2.25	1
Mood Disorders Those disorders that have a disturbance in mood as their predominant feature.	2.25	1
Colorectal Cancer [description not available]	2.31	1
Colonic Polyps Discrete tissue masses that protrude into the lumen of the COLON. These POLYPS are connected to the wall of the colon either by a stalk, pedunculus, or by a broad base.	2.31	1
Colorectal Neoplasms Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.	2.31	1
Chemical Dependence [description not available]	2.41	1
As If Personality [description not available]	2.41	1
Substance-Related Disorders Disorders related to substance use or abuse.	2.41	1

n-(2-acetamido)-2-aminoethanesulfonic acid

Description

Cross-References

Synonyms (53)

Drug Classes (3)

Research

Studies (17)

Market Indicators

Research Demand Index: 20.00

Study Types

n-(2-acetamido)-2-aminoethanesulfonic acid

Description

Cross-References

Synonyms (53)

Drug Classes (3)

Research

Studies (17)

Market Indicators

Research Demand Index: 20.00

Study Types

Related Drugs (16)

Related Conditions (21)