dilazep has been researched along with Hypertension in 4 studies
Dilazep: Coronary vasodilator with some antiarrhythmic activity.
dilazep : A member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dilazep, a coronary vasodilating drug with adenosine-mediated activity, was tested (acute double-blind study versus placebo) for its antihypertensive activity in 12 patients who had mild to moderate hypertension." | 5.06 | Intravenous dilazep reduces blood pressure and peripheral vascular resistance in humans. ( Carnovali, M; Masotti, G; Poggesi, L; Serneri, GG, 1988) |
| "Dilazep did not produce any significant changes in heart rate and blood pressure after a single oral dose or during chronic dosing." | 1.28 | Therapeutic tolerance, hemodynamic effects, and oral dose kinetics of dilazep dihydrochloride in hypertensive patients. ( Gudenzi, M; Kannan, R; Ookhtens, M; Sambhi, MP; Thananopavarn, C, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Itoh, T | 1 |
| Abe, K | 1 |
| Tokumura, M | 1 |
| Hirono, S | 1 |
| Haruna, M | 1 |
| Ibii, N | 1 |
| Kuriyama, S | 1 |
| Tomonari, H | 1 |
| Hosoya, T | 1 |
| Sambhi, MP | 1 |
| Kannan, R | 1 |
| Thananopavarn, C | 1 |
| Ookhtens, M | 1 |
| Gudenzi, M | 1 |
| Poggesi, L | 1 |
| Masotti, G | 1 |
| Serneri, GG | 1 |
| Carnovali, M | 1 |
1 trial available for dilazep and Hypertension
| Article | Year |
|---|---|
Intravenous dilazep reduces blood pressure and peripheral vascular resistance in humans.
Topics: Adult; Azepines; Blood Pressure; Clinical Trials as Topic; Dilazep; Double-Blind Method; Female; Hum | 1988 |
3 other studies available for dilazep and Hypertension
| Article | Year |
|---|---|
Cardiac mechanical dysfunction induced by ischemia-reperfusion in perfused heart isolated from stroke-prone spontaneously hypertensive rats.
Topics: Adenine Nucleotides; Animals; Antihypertensive Agents; Cardiomegaly; Dilazep; Diltiazem; Hypertensio | 2004 |
Antiplatelet therapy decreases the incidence of erythropoietin-induced hypertension in predialysis patients.
Topics: Adult; Aged; Anemia; Dilazep; Dipyridamole; Erythropoietin; Female; Hematocrit; Humans; Hypertension | 1999 |
Therapeutic tolerance, hemodynamic effects, and oral dose kinetics of dilazep dihydrochloride in hypertensive patients.
Topics: Administration, Oral; Adult; Aged; Azepines; Blood Pressure; Dilazep; Drug Tolerance; Heart Rate; Hu | 1989 |