Compounds > 1-(3-chlorophenyl)piperazine
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1-(3-chlorophenyl)piperazine and Hypertension

1-(3-chlorophenyl)piperazine has been researched along with Hypertension in 2 studies

1-(3-chlorophenyl)piperazine: supposed metabolite of TRAZODONE; RN given refers to parent cpd; structure
1-(3-chlorophenyl)piperazine : A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"Eleven (42%) of the patients with PTSD experienced yohimbine-induced panic attacks and had significantly greater increases compared with controls in anxiety, panic, and PTSD symptoms, but not in cardiovascular measurements."5.08Noradrenergic and serotonergic function in posttraumatic stress disorder. ( Bremner, JD; Charney, DS; Heninger, GR; Johnson, DR; Krystal, JH; Morgan, CA; Nagy, LM; Nicolaou, AL; Southwick, SM, 1997)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Southwick, SM1
Krystal, JH1
Bremner, JD1
Morgan, CA1
Nicolaou, AL1
Nagy, LM1
Johnson, DR1
Heninger, GR1
Charney, DS1
Cohen, ML1
Kurz, KD1
Fuller, RW1

Trials

1 trial available for 1-(3-chlorophenyl)piperazine and Hypertension

ArticleYear
Noradrenergic and serotonergic function in posttraumatic stress disorder.
    Archives of general psychiatry, 1997, Volume: 54, Issue:8

    Topics: Adult; Double-Blind Method; Humans; Hypertension; Male; Norepinephrine; Panic Disorder; Piperazines;

1997

Other Studies

1 other study available for 1-(3-chlorophenyl)piperazine and Hypertension

ArticleYear
Effect of meta-chlorophenylpiperazine (mCPP), a central serotonin agonist and vascular serotonin receptor antagonist, on blood pressure in SHR.
    Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:10

    Topics: Animals; Blood Pressure; Brain; Heart Rate; Hypertension; Indoles; Male; Piperazines; Rats; Rats, In

1987