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diphenyleneiodonium and Hypertension

diphenyleneiodonium has been researched along with Hypertension in 10 studies

diphenyleneiodonium: structure in first source; NADPH oxidase inhibitor
dibenziodolium : An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"Hypertensive nephrosclerosis is characterized by activation of the renin-angiotensin-aldosterone system in combination with an inflammatory response characterized by an infiltration of T-cells and mononuclear cells, which release proinflammatory cytokines like IL-1beta/TNFalpha."1.35Synergistic induction of osteopontin by aldosterone and inflammatory cytokines in mesangial cells. ( Gauer, S; Geiger, H; Goppelt-Struebe, M; Hauser, IA; Holzmann, Y; Obermüller, N, 2008)
"Hypertension was induced in rats by abdominal aortic banding (Ab)."1.32Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system. ( Csiszar, A; Kaminski, PM; Koller, A; Ungvari, Z; Wolin, MS, 2004)
" Superoxide anion (O(2)(-)) is a major determinant of nitric oxide (NO) bioavailability and thus endothelial function."1.31Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction. ( Brosnan, MJ; Dominiczak, AF; Graham, D; Hamilton, CA; McIntyre, M, 2001)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's7 (70.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, P1
Zhang, HM1
Hu, K1
Zhou, XF1
Tang, S1
Yu, P1
Han, W1
Villar, VA1
Yang, Y1
Lu, Q1
Lee, H1
Li, F1
Quinn, MT2
Gildea, JJ1
Felder, RA1
Jose, PA1
Chan, SH1
Wu, CA1
Wu, KL1
Ho, YH1
Chang, AY1
Chan, JY1
Qian, JS1
Pang, RP1
Zhu, KS1
Liu, DY1
Li, ZR1
Deng, CY1
Wang, SM1
Ungvari, Z1
Csiszar, A1
Kaminski, PM1
Wolin, MS1
Koller, A1
Lappas, G1
Daou, GB1
Anand-Srivastava, MB1
Gauer, S1
Hauser, IA1
Obermüller, N1
Holzmann, Y1
Geiger, H1
Goppelt-Struebe, M1
Di Wang, H1
Hope, S1
Du, Y1
Cayatte, A1
Pagano, PJ1
Cohen, RA1
Hamilton, CA1
Brosnan, MJ1
McIntyre, M1
Graham, D1
Dominiczak, AF1
Wu, R1
Millette, E1
Wu, L1
de Champlain, J1

Other Studies

10 other studies available for diphenyleneiodonium and Hypertension

ArticleYear
Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia.
    Journal of cellular physiology, 2019, Volume: 234, Issue:8

    Topics: Amides; Animals; Apoptosis; Blood Pressure; Carotid Body; Disease Models, Animal; Endothelin-1; Enzy

2019
Unique role of NADPH oxidase 5 in oxidative stress in human renal proximal tubule cells.
    Redox biology, 2014, Volume: 2

    Topics: Cells, Cultured; Gene Expression Regulation, Enzymologic; Humans; Hypertension; Ionomycin; Isoenzyme

2014
Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension.
    Circulation research, 2009, Oct-23, Volume: 105, Issue:9

    Topics: Adenosine Triphosphate; Angiotensin II; Animals; Antioxidants; Blood Pressure; Blood Vessels; Catala

2009
Static pressure promotes rat aortic smooth muscle cell proliferation via upregulation of volume-regulated chloride channel.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2009, Volume: 24, Issue:5-6

    Topics: Acetophenones; Animals; Aorta; Cell Proliferation; Chloride Channels; Gene Knockdown Techniques; Hyp

2009
Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.
    The American journal of pathology, 2004, Volume: 165, Issue:1

    Topics: Acetophenones; Acetylcholine; Alkaloids; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; A

2004
Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats.
    Journal of hypertension, 2005, Volume: 23, Issue:12

    Topics: Acetylcysteine; Adenylyl Cyclases; Animals; Antioxidants; Cells, Cultured; Colforsin; Flavonoids; GT

2005
Synergistic induction of osteopontin by aldosterone and inflammatory cytokines in mesangial cells.
    Journal of cellular biochemistry, 2008, Feb-01, Volume: 103, Issue:2

    Topics: Aldosterone; Animals; Chemotaxis, Leukocyte; Drug Synergism; Hypertension; Interleukin-1beta; Mesang

2008
Paracrine role of adventitial superoxide anion in mediating spontaneous tone of the isolated rat aorta in angiotensin II-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:5

    Topics: Acridines; Angiotensin II; Animals; Anions; Aorta, Thoracic; Calcium; Data Interpretation, Statistic

1999
Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2

    Topics: Acetophenones; Aging; Animals; Aorta; Blood Pressure; Carotid Arteries; Endothelium, Vascular; Enzym

2001
Enhanced superoxide anion formation in vascular tissues from spontaneously hypertensive and desoxycorticosterone acetate-salt hypertensive rats.
    Journal of hypertension, 2001, Volume: 19, Issue:4

    Topics: Aging; Animals; Aorta; Blood Pressure; Cells, Cultured; Desoxycorticosterone; Ditiocarb; Enzyme Inhi

2001