aldosterone has been researched along with Hypertension in 5104 studies
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Excerpt | Relevance | Reference |
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" Prostasin was measured in plasma and urine from type 2 diabetic patients with resistant hypertension (n = 112) randomized to spironolactone/placebo in a clinical trial." | 9.24 | Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin. ( Bistrup, C; Hansen, MR; Hansen, PB; Hinrichs, GR; Jacobsen, IA; Jensen, BL; Kurt, B; Oxlund, C; Schwarzensteiner, I; Stæhr, M; Svenningsen, P; Thuesen, AD; Toft, A, 2017) |
"Angiotensin II receptor blockers (ARBs) have been widely used to treat hypertension and large-scale clinical studies have shown various benefits." | 9.22 | Changeover Trial of Azilsartan and Olmesartan Comparing Effects on the Renin-Angiotensin-Aldosterone System in Patients with Essential Hypertension after Cardiac Surgery (CHAOS Study). ( Arimoto, M; Hata, H; Osaka, S; Sakino, H; Sezai, A; Shiono, M; Yaoita, H, 2016) |
"To address the cardiovascular mechanisms involved in response to an angiotensin II receptor antagonist, losartan, and continuous positive airway pressure (CPAP) as add-on treatment for hypertension and OSA." | 9.22 | Neuroendocrine and Inflammatory Responses to Losartan and Continuous Positive Airway Pressure in Patients with Hypertension and Obstructive Sleep Apnea. A Randomized Controlled Trial. ( Lindberg, C; Manhem, K; Peker, Y; Rosengren, A; Thunström, E; Yucel-Lindberg, T, 2016) |
"5 mg hydrochorothiazide + 5 mg amlodipine, 86 patients with resistant hypertension were randomized to the add-on 25 mg spironolactone (MRB group, n = 46) or 5 mg ramipril (RASB group, n = 40) groups for 12 weeks." | 9.19 | Greater efficacy of aldosterone blockade and diuretic reinforcement vs. dual renin-angiotensin blockade for left ventricular mass regression in patients with resistant hypertension. ( Azizi, M; Bobrie, G; Chatellier, G; Frank, M; Ménard, J; Perdrix, L; Plouin, PF, 2014) |
"The purpose of this study was to evaluate the effects of spironolactone on dialysis patients with refractory hypertension and possible adverse effects." | 9.19 | Effects of spironolactone on dialysis patients with refractory hypertension: a randomized controlled study. ( Chen, J; Ni, X; Wu, F; Xia, M; Ying, G; Zhang, J; Zhang, P, 2014) |
"The aim was to compare the antiproteinuric effect of aliskiren and ramipril in hypertensive patients with type 2 diabetes and microalbuminuria." | 9.17 | Time course of antiproteinuric effect of aliskiren in arterial hypertension associated with type 2 diabetes and microalbuminuria. ( Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Perrone, T; Preti, P; Zoppi, A, 2013) |
"The primary objective of this study was to evaluate the antihypertensive effect of low dose spironolactone added to triple therapy for resistant hypertension in patients with type 2 diabetes measured by ambulatory monitoring." | 9.17 | Low dose spironolactone reduces blood pressure in patients with resistant hypertension and type 2 diabetes mellitus: a double blind randomized clinical trial. ( Gram, J; Henriksen, JE; Jacobsen, IA; Oxlund, CS; Schousboe, K; Tarnow, L, 2013) |
" We conducted an open-label, randomized trial to compare the effects of cilnidipine against those of amlodipine on blood pressure (BP), albuminuria, and plasma aldosterone concentration in hypertensive patients with mild- to moderate-stage chronic kidney disease." | 9.17 | L/N-type calcium channel blocker cilnidipine reduces plasma aldosterone, albuminuria, and urinary liver-type fatty acid binding protein in patients with chronic kidney disease. ( Abe, M; Inoshita, A; Maruyama, N; Okada, K; Soma, M; Suzuki, H; Yoshida, Y, 2013) |
" We wanted to test the hypotheses that amiloride and spironolactone induced potassium retention reduces ambulatory blood pressure (ABP) and central blood pressure (CBP) during baseline conditions and after furosemide and that the tubular transport via the epithelial sodium channels (ENaCs) and aquaporin-2 (AQP2) water channels was increased by furosemide in arterial hypertension." | 9.17 | Effect of amiloride and spironolactone on renal tubular function and central blood pressure in patients with arterial hypertension during baseline conditions and after furosemide: a double-blinded, randomized, placebo-controlled crossover trial. ( Jensen, JM; Larsen, T; Lauridsen, TG; Matthesen, SK; Pedersen, EB; Vase, H, 2013) |
" In this study, we conducted an open-label and randomized trial to compare the effects of benidipine with those of amlodipine on blood pressure (BP), albuminuria and aldosterone concentration in hypertensive patients with mild-to-moderate stage chronic kidney disease (CKD)." | 9.15 | Benidipine reduces albuminuria and plasma aldosterone in mild-to-moderate stage chronic kidney disease with albuminuria. ( Abe, M; Fujita, T; Maruyama, N; Maruyama, T; Matsumoto, K; Matsumoto, S; Okada, K; Soma, M, 2011) |
"The Ouabain and Adducin for Specific Intervention on Sodium in Hypertension (OASIS-HT) Trial was a phase-2 dose-finding study of rostafuroxin, a digitoxygenin derivative, which selectively antagonizes the effects of endogenous ouabain (EO) on Na+,K+-ATPase and mutated adducin." | 9.15 | Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin. ( Bacchieri, A; Barton, J; Bianchi, G; Citterio, L; de Leeuw, PW; Dłużniewski, M; Espositi, ED; Ferrari, P; Glorioso, N; Januszewicz, A; Kawecka-Jaszcz, K; Lanzani, C; Manunta, P; Milyagin, V; Nikitin, Y; Souček, M; Staessen, JA; Stolarz-Skrzypek, K; Thijs, L; Timio, M; Tykarski, A; Valentini, G, 2011) |
"The Aliskiren in Left Ventricular Hypertrophy (ALLAY) trial randomised 465 hypertensive overweight subjects with LVH to the direct renin inhibitor aliskiren 300 mg, losartan 100 mg or the combination and followed patients for 9 months." | 9.15 | Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertension. ( Appelbaum, E; Dahlöf, B; Desai, A; Lukashevich, V; Pouleur, AC; Prescott, MF; Smith, BA; Solomon, SD; Uno, H, 2011) |
"Participants enrolled in this trial were outpatients with essential hypertension after cardiac surgery who had received candesartan for more than one year." | 9.15 | Effects of olmesartan on the renin-angiotensin-aldosterone system for patients with essential hypertension after cardiac surgery--investigation using a candesartan change-over study. ( Hata, M; Sezai, A; Shiono, M; Soma, M; Unosawa, S; Wakui, S; Yoshitake, I, 2011) |
" Spironolactone is thought to be an important addition to resistant hypertension (RH) treatment." | 9.14 | Aldosterone excess or escape: Treating resistant hypertension. ( Adriana de Souza, L; Coca, A; Coelho, OR; Ferreira-Melo, S; Martins, LC; Moreno, H; Pimenta, E; Sierra, C; Ubaid-Girioli, S; Yugar-Toledo, JC, 2009) |
"Forty type 2 diabetic patients with hypertension and nephropathy receiving angiotensin receptor II blockers were enrolled and randomly divided into two groups: the efonidipine group was administered efonidipine hydrochloride ethanolate 40 mg/day and the amlodipine group was admin-istered amlodipine besilate 5 mg/day for 12 months." | 9.14 | Protective effects of efonidipine, a T- and L-type calcium channel blocker, on renal function and arterial stiffness in type 2 diabetic patients with hypertension and nephropathy. ( Ban, N; Endo, K; Kawana, H; Miyashita, Y; Nagayama, D; Ohhira, M; Oyama, T; Saiki, A; Sasaki, H; Shirai, K; Yamaguchi, T, 2009) |
"This study was conducted to determine the effects of a tablet combining losartan/hydrochlorothiazide (L/HCTZ) in comparison with losartan alone in Japanese diabetic patients with hypertension." | 9.14 | Safety and benefits of a tablet combining losartan and hydrochlorothiazide in Japanese diabetic patients with hypertension. ( Ichihara, A; Itoh, H; Kinouchi, K; Kurauchi-Mito, A; Sakoda, M, 2009) |
"A total of 50 stable outpatients with essential hypertension who had received candesartan for more than 1 year were randomized into two groups: control group (n=25): continuous candesartan treatment at a stable dose; and olmesartan group (n=25): candesartan (8 mg day(-1)) was changed to olmesartan given at a dose of 20 mg day(-1)." | 9.14 | Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension. ( Fujii, M; Horie, M; Kawahara, C; Nishiyama, K; Tsutamoto, T; Yamaji, M; Yamamoto, T, 2010) |
"A common pharmacologic test for the diagnosis of primary aldosteronism (PA) is the administration of captopril to determine whether an abnormal plasma aldosterone concentration (PAC) to plasma renin activity (PRA) ratio(ARR) persists, although active renin concentration (ARC) may offer advantages with regard to processing and standardization." | 9.14 | Diagnosis of primary aldosteronism: comparison of post-captopril active renin concentration and plasma renin activity. ( Chang, CC; Chang, HW; Chueh, SC; Fang, CC; Ho, YL; Huang, KH; Kuo, CC; Lin, CY; Lin, LY; Lin, SL; Lin, YH; Liu, KL; Tsai, CT; Wang, SM; Wu, KD; Wu, VC; Yen, RF, 2010) |
"The aim of the study was evaluation of spironolactone effect on concentration of endothelin-1 (ET-1 - vasoconstrictive substance produced by endothelial cells) and aldosterone (Ald) and plasma renin activity (PRA) in patients with primary arterial hypertension (AH): group A--smoking patients (11 individuals) in comparison with group B--non-smoking ones (12 individuals)." | 9.14 | [Does spironolactone use at arterial hypertension therapy protect endothelium also in smoking patients?]. ( Kara-Perz, H; Kosicka, T; Perz, S, 2009) |
" We investigated the hypothesis that simvastatin decreased muscle sympathetic nerve activity (MSNA) in 31 hypertensive subjects with hypercholesterolemia (aged 38." | 9.14 | Simvastatin reduces sympathetic activity in men with hypertension and hypercholesterolemia. ( Abramczyk, P; Bidiuk, J; Ciarka, A; Dobosiewicz, A; Gaciong, Z; Lewandowski, J; Siński, M, 2010) |
"In this study we evaluated the effect of a dual blockade with enalapril and losartan on the reduction of overt macroproteinuria and its potential mechanism(s) in hypertensive patients with type 2 diabetes." | 9.12 | Dual blockade of angiotensin II with enalapril and losartan reduces proteinuria in hypertensive patients with type 2 diabetes. ( Hirata, A; Igarashi, M; Kadomoto, Y; Tominaga, M, 2006) |
"The patients with essential hypertension were randomly divided into 2 groups; 1 group was treated with an ARB, candesartan (8 mg/day), for 1 year (ARB group) and other group was treated with the ARB for the first 6 months and with the ARB plus SPRL (25 mg/day) for the next 6 months (combination group)." | 9.12 | Effects of spironolactone during an angiotensin II receptor blocker treatment on the left ventricular mass reduction in hypertensive patients with concentric left ventricular hypertrophy. ( Date, T; Kawai, M; Mochizuki, S; Seki, S; Shimizu, M; Taniguchi, I; Taniguchi, M; Yoshida, S, 2006) |
" It is not known if subjects with a high ratio have aldosteronism or aldosterone-sensitive hypertension is debated but it is important to know whether spironolactone is superior to other diuretics such as bendroflumethiazide in this setting." | 9.12 | Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study. ( Alhashmi, K; Connell, JM; Ford, I; MacDonald, TM; McInnes, GT; McMahon, AD; Parthasarathy, HK; Struthers, AD, 2007) |
"One hundred eighteen patients with mild-to-moderate essential arterial hypertension were randomized to treatment with 10 mg/d of amlodipine (group 1), 20 mg/d of quinapril (group 2), or 2 x 50 mg/d of losartan (group 3)." | 9.10 | Effect of amlodipine, quinapril, and losartan on pulse wave velocity and plasma collagen markers in patients with mild-to-moderate arterial hypertension. ( Kawecka-Jaszcz, K; Klocek, M; Rajzer, M, 2003) |
"Eplerenone is a highly selective aldosterone blocking agent, which was recently approved for the treatment of hypertension and has also been shown to reduce mortality in post-myocardial infarction patients with heart failure." | 9.10 | Assessment of the novel selective aldosterone blocker eplerenone using ambulatory and clinical blood pressure in patients with systemic hypertension. ( Carr, AA; Jordan, R; Krause, S; Oigman, W; Roniker, B; White, WB, 2003) |
"Previous reports have demonstrated the antihypertensive efficacy of high doses of spironolactone in subjects with primary aldosteronism and, to a lesser degree, subjects with resistant hypertension." | 9.10 | Efficacy of low-dose spironolactone in subjects with resistant hypertension. ( Calhoun, DA; Nishizaka, MK; Zaman, MA, 2003) |
"Patients with mild-to-moderate primary hypertension and left ventricular hypertrophy were randomized in a double-blind study to receive treatment with either the angiotensin II type 1 (AT1) receptor antagonist irbesartan (n = 43), or the beta1-adrenergic receptor blocker atenolol (n = 43)." | 9.10 | Aldosterone synthase (CYP11B2) -344 C/T polymorphism is related to antihypertensive response: result from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial. ( Hägg, A; Kahan, T; Karlsson, J; Kurland, L; Lind, L; Malmqvist, K; Melhus, H; Nyström, F; Ohman, P, 2002) |
" In the present study, we examined the effect on left ventricular hypertrophy of adding a low dose of the mineralocorticoid receptor antagonist spironolactone (25 mg/d) to an angiotensin-converting enzyme inhibitor (enalapril maleate) in patients with essential hypertension." | 9.09 | Effects of spironolactone and angiotensin-converting enzyme inhibitor on left ventricular hypertrophy in patients with essential hypertension. ( Saruta, T; Sato, A; Suzuki, Y, 1999) |
"To determine the relationship between endothelin-1 (ET-1), human atrial natriuretic peptide (hANP), plasma-renin activity (PRA) and 24-h urinary excretion of aldosterone (U-Ald) in pregnancy-induced hypertension (PIH)." | 9.09 | Plasma human atrial natriuretic peptide, endothelin-1, aldosterone and plasma-renin activity in pregnancy-induced hypertension. ( Bogdanovska, SV; Gerasimovska, BD; Lozance, LA; Maleska, VT; Masin-Paneva, J; Zafirovska, KG, 1999) |
"Since renal sympathetic nerves are involved in the regulation of sodium excretion, we investigated whether treatment with urapidil, an alpha1-adrenoceptor blocking agent which also lowers sympathetic activity, alters sodium excretory capacity in patients with essential hypertension." | 9.09 | Renal haemodynamics and sodium excretory capacity during urapidil treatment in patients with essential hypertension. ( de Leeuw, PW; Fuss-Lejeune, M; Kroon, AA; Lavrijssen, AT; Schiffers, PM, 2000) |
"This multicenter study evaluated the efficacy of candesartan cilexetil, an angiotensin II type 1 receptor antagonist, used alone or in combination with amlodipine or in combination with amlodipine and hydrochlorothiazide in the treatment of patients with moderate-to-severe essential hypertension." | 9.09 | Efficacy of candesartan cilexetil alone or in combination with amlodipine and hydrochlorothiazide in moderate-to-severe hypertension. UK and Israel Candesartan Investigators. ( Antonios, TF; He, FJ; MacGregor, GA; Viskoper, JR, 2000) |
"We examined the effects of the vasodilator peptide adrenomedullin (AM) infused intravenously into subjects with essential hypertension." | 9.09 | Hemodynamic, hormone, and urinary effects of adrenomedullin infusion in essential hypertension. ( Lewis, LK; Nicholls, MG; Richards, AM; Troughton, RW; Yandle, TG, 2000) |
"The aim of this study was to investigate the effect of short-term treatment with losartan, a selective and competitive angiotensin II (AngII) receptor blocker, on vascular endothelial growth factor (VEGF), active renin and kallikrein activity (KA) in patients with essential hypertension and primary aldosteronism." | 9.09 | Effect of short-term losartan treatment in patients with primary aldosteronism and essential hypertension. ( Atanassova, I; Natchev, E; Orbetzova, M; Tzingilev, D; Zacharieva, S, 2001) |
"To examine the factors that determine the blood pressure response to enalapril and nifedipine monotherapy in the treatment of hypertension associated with non-insulin-dependent diabetes mellitus (NIDDM)." | 9.08 | Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM. ( Chan, JC; Cheung, CK; Cockram, CS; Law, LK; Nicholls, MG; Swaminathan, R, 1995) |
"The effect of calcium channel blocker (CCB), amlodipine (5-10 mg/day) and angiotensin-converting enzyme (ACE) inhibitor, quinapril (10-40 mg/day) on ambulatory blood pressure (ABP), rheological and platelet function in hypertension were compared in this randomised double-blind placebo-controlled cross-over study." | 9.08 | Comparison of amlodipine and quinapril on ambulatory blood pressure and platelet function in hypertension. ( Chang, SM; Chou, TC; Ding, YA, 1995) |
"In forty six hypertensive patients in whom a high level of clinical suspicion for renovascular hypertension was present on the basis of clinical clues, a captopril test was performed with either 25 mg of captopril or placebo on 2 separate days to determine prospectively the value of the captopril test." | 9.08 | 'Captopril test', with blood pressure and peripheral renin as response variables in hypertensive patients with suspected renal artery stenosis. ( de Leeuw, PW; Lavrijssen, AT; Schiffers, PM; Schreij, G; van Es, PN, 1995) |
"The effects of inhibition of the renin-angiotensin system with quinapril on adrenergic transmission were determined in 18 patients with moderate essential hypertension." | 9.08 | Quinapril ACE-inhibition effects on adrenergic parameters in moderate essential hypertension. ( Bronsoms Artero, J; Matas Serra, M; Matè Benito, G; Mauri Nicolas, JM; Torguet Escuder, P; Vallès Prats, M, 1996) |
"The effects of two types of angiotensin converting enzyme (ACE) inhibitors, enalapril (long-acting) and captopril (short-acting), on serum electrolytes and circadian rhythm of urinary electrolyte excretions were compared in relation to aldosterone status in patients with essential hypertension and normal renal function." | 9.07 | Crossover comparison of the effects of enalapril and captopril on potassium homeostasis in patients with mild hypertension. ( Abe, I; Fujishima, M; Kobayashi, K; Ohmori, S; Ohya, Y; Takata, Y; Tominaga, M; Ueno, M, 1994) |
"The present study was performed to clarify changes in plasma levels of 19-hydroxyandrostenedione (19-OH-AD), an amplifier of aldosterone and a possible hypertensinogenic steroid, during several tests for the renin-angiotensin system in 20 patients with aldosterone-producing adenoma (APA) and to determine whether 19-OH-AD participates in the etiology of the hypertension in this disorder." | 9.07 | Low plasma 19-hydroxyandrostenedione levels in patients with aldosterone-producing adenoma. ( Miura, K; Miyazaki, S; Morita, H; Mune, T; Yamakita, N; Yasuda, K, 1993) |
"The authors assessed in 20 subjects with mild or medium severe arterial hypertension basal and stimulated values of plasma renin activity (PRA) and aldosterone before onset of treatment and after 6-week therapy with enalapril (ENAP KRKA) or metoprolol (Vasocardin Slovakofarma)." | 9.07 | [The importance of studying the renin-angiotensin-aldosterone system in essential arterial hypertension in clinical practice. Activity of the renin-angiotensin-aldosterone system during treatment of hypertension with ACE-inhibitors and beta blockers]. ( Chamulová, M; Hrnciar, J; Hrnciarová, M; Kreze, A; Lepej, J; Okálová, D, 1994) |
"Ketanserin, a serotonin-2-receptor antagonist, was administered to 16 patients with mild to moderate essential hypertension in randomized single-blind placebo controlled study." | 9.07 | [Influence of chronic ketanserin therapy on blood pressure and certain humoral and metabolic factors in patients with mild to moderate primary essential hypertension]. ( Berent, H; Brym, E; Czerniewska, E; Januszewicz, W; Knypl, K; Kuçzyńska, K; Wacławek-Maczkowska, J; Wasowska, T; Wocial, B, 1993) |
" After a two-week, placebo run-in phase, 110 patients with mild to moderate hypertension were randomised to receive 10 mg lisinopril or enalapril, or placebo for 4 weeks." | 9.07 | Twenty-four hour blood pressure effect of once-daily lisinopril, enalapril, and placebo in patients with mild to moderate hypertension. ( Dunne, B; Glazer, N; Kostis, JB; Miller, WE; Rector, DJ; Tresznewsky, ON; Whelton, A, 1992) |
"The effects of a sustained-release formulation of the calcium antagonist nicardipine on left ventricular (LV) mass, Doppler transmitral velocity profiles and plasma neurohumoral studies were analyzed in patients with mild to moderate systemic hypertension." | 9.07 | Effects of sustained-release nicardipine on regression of left ventricular hypertrophy in systemic hypertension. ( Adler, J; Dittrich, HC; Ong, J; Reitman, M; Weber, M; Ziegler, M, 1992) |
"The short-term effects of atenolol and nifedipine on plasma levels of atrial natriuretic peptide (ANP), plasma renin activity (PRA), and plasma aldosterone (PA) were studied in two groups of patients with uncomplicated essential hypertension." | 9.07 | Short-term effects of atenolol and nifedipine on atrial natriuretic peptide, plasma renin activity, and plasma aldosterone in patients with essential hypertension. ( Bucci, V; Casale, R; Colantonio, D; Desiati, P; Giandomenico, G; Pasqualetti, P, 1991) |
"Nifedipine causes an acute and a sustained reduction in sodium balance in patients with essential hypertension." | 9.07 | Acute and sustained changes in sodium balance during nifedipine treatment in essential hypertension. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR, 1991) |
"The effects of 6 weeks of treatment with dilevalol 100 mg once daily, or carteolol 10 mg once daily, on renal blood flow (RBF), glomerular filtration rate (GFR) and total renal vascular resistance (TRR) were studied in 10 patients with mild-to-moderate essential hypertension in a randomised cross-over experiment." | 9.06 | Comparison of the renal effects of dilevalol and carteolol in patients with mild to moderate essential hypertension. ( Baba, T; Murabayashi, S; Takebe, K; Tomiyama, T, 1990) |
"The renal, metabolic and antihypertensive effects of enalapril (E) and slow-release verapamil (V) were compared in a 2-month double-blind crossover trial in 22 patients with newly discovered essential hypertension." | 9.06 | Antihypertensive and renal effects of enalapril and slow-release verapamil in essential hypertension. A double-blind, randomized study. ( Fagher, B; Henningsen, N; Hulthén, L; Katzman, P; Thulin, T, 1990) |
"The purpose of the study was to evaluate the effects of a dihydropyridine calcium antagonist, nicardipine (N), on blood pressure (BP) and aldosterone secretion in hypertensive patients (pt) with primary aldosteronism." | 9.06 | [Effect of a calcium inhibitor, nicardipine, on aldosterone secretion in primary hyperaldosteronism]. ( Begasse, F; Chamontin, B; David, D; Salvador, M, 1989) |
" To investigate the contribution of sedation to the cardiovascular effects induced by clonidine, we studied patients with essential hypertension on two separate occasions when similar levels of sedation were induced by clonidine and nitrazepam." | 9.06 | The haemodynamic and hormonal responses after clonidine occur independently of sedation in essential hypertension. ( Kooner, JS; Mathias, CJ; Peart, WS, 1989) |
"This double-blind placebo controlled study investigated the antihypertensive and humoral effects of nifedipine capsules in patients with essential hypertension inadequately controlled (seated diastolic blood pressure greater than or equal to 95 mm Hg) by hydrochlorothiazide (HCTZ) alone." | 9.06 | Antihypertensive and humoral effects of nifedipine in essential hypertension uncontrolled by hydrochlorothiazide alone. ( Abraham, PA; Halstenson, CE; Opsahl, JA, 1989) |
"The effects of enalapril alone and in combination with the cyclooxygenase inhibitors sulindac and indomethacin on blood pressure (BP), plasma aldosterone, renin activity and converting enzyme activity were evaluated in 29 patients with mild to moderate essential hypertension, 26 of whom had low plasma renin activity." | 9.06 | Antihypertensive effect of enalapril in essential hypertension: role of prostacyclin. ( Hammett, DK; Horton, R; Irvin, J; Oparil, S; Wilkins, LH, 1987) |
"A series of studies were undertaken to assess the effect of oral fenoldopam, a specific DA1 dopamine receptor agonist on blood pressure and renal function in patients with mild essential hypertension." | 9.06 | Studies with fenoldopam, a dopamine receptor DA1 agonist, in essential hypertension. ( Brown, J; Harvey, JN; Lee, MR; Worth, DP, 1986) |
"The effects of the addition of a calcium entry antagonist, nifedipine (20-mg tablet twice a day), to an angiotensin converting enzyme inhibitor, captopril (25 mg three times a day), and the addition of captopril to nifedipine were observed in two separate studies in patients with essential hypertension." | 9.06 | Captopril and nifedipine in combination for moderate to severe essential hypertension. ( MacGregor, GA; Markandu, ND; Shore, AC; Singer, DR, 1987) |
" In nine patients with essential hypertension, following single and multiple doses of ketanserin, assessments were made of blood pressure and heart rate, QT interval, and pressor responses to phenylephrine and angiotensin II." | 9.06 | Acute and chronic ketanserin in essential hypertension: antihypertensive mechanisms and pharmacokinetics. ( Donnelly, R; Elliott, HL; Meredith, PA; Reid, JL, 1987) |
"The efficacy and tolerability of the new ACE-inhibitor enalapril (MK 421) and the beta 1-selective adrenoceptor blocker atenolol for the treatment of primary hypertension were compared in a double blind parallel study." | 9.05 | Enalapril and atenolol in primary hypertension--a comparative study of blood pressure lowering and hormonal effects. ( Karlberg, BE; Ohman, KP, 1984) |
"The hormonal and hypotensive effects of a single oral 10 mg dose of enalapril (MK-421), were assessed by a double-blind randomized trial in 12 subjects with essential hypertension, during a 100 and 40 mmol/day sodium intake." | 9.05 | Effect of dietary sodium on angiotensin-converting enzyme (ACE) inhibition and the acute hypotensive effect of enalapril (MK-421) in essential hypertension. ( Cubela, R; Jackson, B; Johnston, CI, 1984) |
" In 14 patients with mild to moderate essential hypertension, the effects of bucindolol, hydrochlorothiazide and their combination on blood pressure (BP), heart rate (HR) and parameters of the renin-aldosterone system were compared with those after placebo." | 9.05 | Bucindolol, a beta-adrenoceptor blocker with vasodilatory action: its effect in systemic hypertension. ( Fedder, IL; Ferguson, RK; Rocci, ML; Rotmensch, HH; Soyka, L; Swanson, BN; Vlasses, PH, 1984) |
"The aim of this study was to investigate and compare the effects of two calcium antagonist drugs, verapamil (VER) and nifedipine (NIF), on blood pressure (BP), heart rate (HR), plasma catecholamines (pCA), renin (PRA), plasma aldosterone (pALD), and plasma volume (PV) in a group of patients with mild to moderate essential hypertension." | 9.05 | Antihypertensive and humoral effects of verapamil and nifedipine in essential hypertension. ( Agabiti-Rosei, E; Alicandri, CL; Beschi, M; Castellano, M; Corea, L; Fariello, R; Muiesan, G; Romanelli, G, 1982) |
"The effect of low doses (25 mg three times a day) of captopril was evaluated in 16 patients with mild to moderate essential hypertension, previously uncontrolled by hydrochlorothiazide." | 9.05 | Low-dose captopril: its use in mild to moderate hypertension unresponsive to diuretic treatment. ( Ferguson, RK; Mojaverian, P; Rotmensch, HH; Swanson, BN; Vlasses, PH, 1982) |
"Eight patients with essential hypertension completed a double-blind, randomly allocated crossover comparison of either 5 or 10 mg enalapril maleate, 50 mg hydrochlorothiazide, or their combination administered once daily during sequential two-week periods." | 9.05 | A comparative pilot study of enalapril, a new converting enzyme inhibitor, and hydrochlorothiazide in essential hypertension. ( Ferguson, RK; Irvin, JD; Lee, RB; Swanson, BN; Vlasses, PH, 1982) |
"The effects of captopril and propranolol on blood pressure, heart rate and plasma noradrenaline, renin and aldosterone, and on the responses to changes in posture and to isometric exercise were measured in patients with essential hypertension." | 9.05 | The effect of captopril and propranolol on the responses to posture and isometric exercise in patients with essential hypertension. ( Goodwin, FJ; Holly, JM; Marsh, FP; Sharman, VL; Vandenburg, MJ, 1983) |
"57 years), with primary arterial hypertension, was submitted to two periods of treatment in a cross-over study with spironolactone and potassium canrenoate." | 9.05 | [Clinical study of the efficacy of oral potassium canrenoate and spironolactone in essential arterial hypertension]. ( Fanti, P; Mantellini, R; Sciarra, F; Tosti-Croce, C, 1983) |
"The effects on blood pressure, the renin-angiotensin-aldosterone and the kallikrein-kinin systems were investigated in 32 patients with primary hypertension WHO stage I-II treated with captopril." | 9.05 | Captopril, aldosterone and urinary kallikrein in primary hypertension. ( Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S, 1983) |
"The metabolic effects of piretanide (2 x 6 mg daily) were compared with those of hydrochlorothiazide, in doses of 2 x 25 mg or 2 x 50 mg daily, in a double-blind study consisting of three parallel groups totalling 15 patients with uncomplicated essential hypertension." | 9.05 | The effects of piretanide on catecholamine metabolism, plasma renin activity and serum aldosterone: a double-blind pilot comparison against hydrochlorothiazide in patients with essential hypertension. ( Bückert, C; Kirsten, R; Verho, M, 1984) |
"Thirty-two patients with moderate to severe essential hypertension whose supine diastolic blood pressure (SDBP) was greater than or equal to 95 mm Hg following 2 weeks' treatment with the optimal dosage of beta blocker-diuretic combination were randomly assigned to the addition of either captopril 25 mg or 50 mg b." | 9.05 | Efficacy of low-dose captopril given twice daily to patients with essential hypertension uncontrolled by a beta blocker plus thiazide diuretic. ( Agabiti-Rosei, E; Alicandri, C; Boni, E; Cinquegrana, A; Fariello, R; Montini, E; Muiesan, G; Muiesan, ML; Zaninelli, A, 1984) |
"Thirty-two patients with primary hypertension were studied in a double-blind cross-over comparison between the cardioselective beta 1-blocking agent atenolol and the combined alpha- and beta-blocking agent labetalol." | 9.05 | Antihypertensive and metabolic effects of increasing doses of atenolol and labetalol. A comparative study in primary hypertension. ( Henningsen, NC; Karlberg, BE; Nilsson, OR; Thulin, T, 1982) |
"Twenty-four patients with moderate to severe hypertension were treated for four weeks with captopril, an oral inhibitor of angiotensin-converting enzyme." | 9.05 | Captopril in essential hypertension; contrasting effects of adding hydrochlorothiazide or propranolol. ( Banks, RA; Bayliss, J; Jones, JC; MacGregor, GA; Markandu, ND; Roulston, JE, 1982) |
"The effects of amiloride hydrochloride on thiazide-induced hypokalemia were evaluated." | 9.05 | Response of thiazide-induced hypokalemia to amiloride. ( Chan, L; Maronde, RF; Milgrom, M; Vlachakis, ND, 1983) |
"The magnitude and duration of the antihypertensive effect of nifedipine were studied in 7 cases of moderate essential hypertension." | 9.05 | Antihypertensive effect of fractionated sublingual administration of nifedipine in moderate essential hypertension. ( Bonnet, F; Corvol, P; Thibonnier, M, 1980) |
"Captopril (SQ 14 225), an orally active inhibitor of angiotensin converting enzyme, was evaluated in the treatment of primary (essential) hypertension in a placebo-controlled long-term study." | 9.05 | Captopril, an orally active converting enzyme inhibitor, in the treatment of primary hypertension. A controlled long-term study with reference to initial plasma renin activity. ( Asplund, J; Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S, 1981) |
"In a single-dose crossover study Captopril (SQ 14225), 1 mg/kg body weight, and Nifedipine (Bay a 1040) 20 mg were administered orally to 12 hospitalized patients with essential hypertension (Stage 1 or 2, W." | 9.05 | Antihypertensive and hormonal effects of single oral doses of captopril and nifedipine in essential hypertension. ( Corvol, P; Menard, J; Milliez, P; Sire, O; Soto, ME; Thibonnier, M, 1981) |
"Thirty patients with mild or moderate essential hypertension, and a fixed elevation of diastolic blood pressure, were randomly allocated to three groups and treated with propranolol 40 mg x 4 (Group 1), 80 mg x 4 (group 2) and 160 mg x 4 (Group 3)." | 9.05 | Correlation between propranolol in plasma and urine, renin-aldosterone system and blood pressure in essential hypertension. ( Andreasen, F; Bjerregaard, P; Kornerup, HJ; Pedersen, EB; Pedersen, OL, 1981) |
"In a double-blind crossover study, the antihypertensive effect of hydrochlorothiazide alone and in combination with the beta blocker acebutolol was assessed in 18 patients suffering from mild to moderate hypertension." | 9.05 | Merits of adding a beta blocker (acebutolol) to a diuretic (hydrochlorothiazide) in the treatment of hypertension. ( Belleau, LJ; Brossard, JJ; Lebel, M, 1982) |
" Since ketanserin, a more specific 5-HT2-serotoninergic (5-HT2) antagonist, has been shown to affect aldosterone secretion in essential hypertension, we have further investigated this mechanism by injecting ketanserin (10 mg i." | 9.05 | Effect of ketanserin in primary aldosteronism. ( Armanini, D; Boscaro, M; D'Agostino, D; Mantero, F; Opocher, G; Rocco, S, 1985) |
"Renal plasma flow, glomerular filtration rate plasma angiotensin II, aldosterone and arginine vasopressin, free water clearance, blood pressure and body weight in 11 patients with mild to moderate hypertension were determined at the end of consecutive 6 week periods of administration of placebo and verapamil up to 120 mg t." | 9.05 | Effect of verapamil on renal plasma flow, glomerular filtration rate and plasma angiotensin II, aldosterone and arginine vasopressin in essential hypertension. ( Danielsen, H; Pedersen, EB; Sørensen, SS; Thomsen, OO, 1985) |
"Effect of long-term administration of propranolol was studied in 90 unselected patients with essential hypertension." | 9.04 | [Treatment of essential hypertension with propranolol (author's transl)]. ( Braun, B; Klaus, D; Klumpp, F; Lemke, R; Zehner, J, 1976) |
" Captopril was shown to be as effective as hydrochlorothiazide in lowering the blood pressure in patients with moderately severe essential hypertension." | 9.04 | Hormonal changes with long-term converting-enzyme inhibition by captopril in essential hypertension. ( Johnston, CI; Matthews, PG; McGrath, BP, 1979) |
"Eighteen patients with diastolic hypertension (100 to 120 mm Hg), in addition to propranolol, 160 mg daily, and hydrochlorothiazide, 100 mg daily, received progressively increased doses of either minoxidil or placebo in a double-blind crossover study." | 9.04 | Effect of minoxidil on blood pressure and hemodynamics in severe hypertension. ( Bryan, RK; Hoobler, SW; Purdy, JM; Rosenzweig, J; Weller, JM, 1977) |
"A double-blind study of hydrochlorothiazide and spironolactone, alone and in combination, was conducted in 49 patients with mild-to-moderate essential hypertension after a 4-wk placebo washout period." | 9.04 | Hydrochlorothiazide and spironolactone in hypertension. ( Schrijver, G; Weinberger, MH, 1979) |
" Plasma renin activity (PRA), the daily urinary excretion of aldosterone (dU-Aldo) and electrolytes were studied before and during dihydralazine therapy (25 mg 3 times daily)." | 9.04 | The renin-aldosterone system in dihydralazine therapy during hypertensive pregnancy. ( Lammintausta, R, 1978) |
"The antihypertensive effect of the selective beta-1-adrenoceptor blocker, metoprolol, administered once daily was evaluated in 32 patients with primary hypertension." | 9.04 | Once-daily metoprolol in primary hypertension. ( Karlberg, BE; Nilsson, O; Nitelius, E; Tolagen, K; Waern, U, 1979) |
"15 patients who had benign, uncomplicated essential hypertension, were treated with chlorthiazide (500 mg twice a day) with or without propranolol (10--20 mg 4 times a day), and the effect of the treatment on plasma renin activity (PRA), urinary aldosterone excretion, total body potassium (TBK) and plasma sodium and potassium was evaluated." | 9.04 | The renin-aldosterone system and thiazide-induced depletion of total body potassium in essential hypertension. ( Carroll, HJ; Oh, MS, 1978) |
" Serial measurements of plasma renin activity (PRA), plasma aldosterone concentration (PA) and blood pressure were performed overnight in patients with borderline (group 1) and sustained essential hypertension (group 2) before and after acute and chronic administration of either propranolol or pindolol." | 9.04 | Differential effects of acute and chronic beta-adrenoreceptor blockade on blood pressure and the renin-angiotensin-aldosterone system in essential hypertension. ( Gramann, W; Kolloch, R; Krück, F; Stumpe, KO; Vetter, H, 1976) |
"To review comparative efficacy and tolerability data between the two main mineralocorticoid receptor antagonists (MRAs), spironolactone and eplerenone, in patients with resistant hypertension (HTN)." | 9.01 | Eplerenone Versus Spironolactone in Resistant Hypertension: an Efficacy and/or Cost or Just a Men's Issue? ( Manolis, AA; Manolis, AS; Manolis, TA; Melita, H, 2019) |
" Angiotensin II and aldosterone often collaborate in pathological situations to induce hypertrophy of cardiomyocytes, vascular inflammation, perivascular and interstitial fibrosis, and microvascular rarefaction." | 8.89 | Aldosterone mediates cardiac fibrosis in the setting of hypertension. ( Azibani, F; Chatziantoniou, C; Delcayre, C; Fazal, L; Samuel, JL, 2013) |
"(2) In RALES, low-dose spironolactone in addition to standard of care, produced a 30% improvement in survival in progressive heart failure, commonly assumed to reflect deleterious effects of aldosterone, with spironolactone competing with aldosterone for cardiac mineralocorticoid receptors." | 8.86 | Aldosterone, hypertension and heart failure: insights from clinical trials. ( Funder, JW, 2010) |
" Angiotensin II, the principal effector peptide of the RAAS, has far-reaching effects on vascular structure, growth and fibrosis, and is a key regulator of vascular remodeling and inflammation." | 8.83 | Role of the renin-angiotensin-aldosterone system in vascular remodeling and inflammation: a clinical review. ( Duprez, DA, 2006) |
"Only recently approved for use in the treatment of hypertension in the US, the beta-adrenergic receptor blocking compound propranolol has been used elsewhere for this purpose since 1964." | 8.75 | Pathophysiology of propranolol in hypertension. ( Frohlich, ED, 1977) |
" It has been reported that sPRR functions as an important regulator of intrarenal renin contributing to angiotensin II (ANG II)-induced hypertension." | 8.31 | Mutagenesis of the cleavage site of (pro)renin receptor abrogates aldosterone-salt-induced hypertension and renal injury in mice. ( Chen, Y; Fu, Z; Kaewsaro, K; Lambert, J; Yang, T; Zheng, H, 2023) |
"The authors sought to determine the relationship of circulating angiotensinogen levels to ethnicity, sex, BP, incident hypertension, and prevalent hypertension in a modern sex-balanced ethnically diverse cohort." | 8.31 | Blood Levels of Angiotensinogen and Hypertension in the Multi-Ethnic Study of Atherosclerosis (MESA). ( Brambatti, M; Carlisle, SM; DeFilippis, AP; Kahlon, T; Michos, ED; Morgan, ES; Mostacero, DO; Mousavi, H; Mullick, AE; Ouyang, P; Shah, SJ; Tami, Y; Trainor, PJ; Tsimikas, S, 2023) |
"To study the development of microalbuminuria (MAU) in essential hypertension (EHT), we investigated the association of MAU with central blood pressure (CBP), direct renin concentration (DRC), plasma aldosterone (PA), and uric acid (UA)." | 8.31 | Central diastolic blood pressure, plasma aldosterone and uric acid are associated with microalbuminuria in essential hypertension: a case-control study. ( Chou, H; Li, J; Li, Y; Shi, L; Wei, M; Yang, N, 2023) |
"Activity of the circulating renin-angiotensin-aldosterone system (RAAS) has not been comprehensively characterized in cats with systemic hypertension (SH) or cardiomyopathy (CM), and the effects of furosemide or amlodipine treatment on the RAAS have not been fully evaluated in cats." | 8.12 | Circulating renin-angiotensin-aldosterone system activity in cats with systemic hypertension or cardiomyopathy. ( Domenig, O; Guillot, E; Mochel, JP; Ward, JL; Ware, WA; Yuan, L, 2022) |
"The saline suppression test (SST) and captopril challenge test (CCT) are commonly used confirmatory tests for primary aldosteronism (PA)." | 8.02 | Seated Saline Suppression Test Is Comparable With Captopril Challenge Test for the Diagnosis of Primary Aldosteronism: A Prospective Study. ( Cheng, Q; Du, Z; Feng, Z; He, W; Hu, J; Li, Q; Liu, B; Song, Y; Wang, Z; Xu, Z; Yang, J; Yang, S, 2021) |
"We prospectively enrolled 121 patients with confirmed primary aldosteronism who started mineralocorticoid receptor antagonist (canrenone) treatment." | 8.02 | Mineralocorticoid Receptor Antagonist Effect on Aldosterone to Renin Ratio in Patients With Primary Aldosteronism. ( Avataneo, V; Bertello, C; Buffolo, F; Burrello, J; D'Avolio, A; Mengozzi, G; Monticone, S; Mulatero, P; Pecori, A; Rabbia, F; Rumbolo, F; Veglio, F, 2021) |
"Recent reports described cases of severe hypertension and hypokalemia accompanied by low renin and aldosterone levels during antifungal therapy with posaconazole and itraconazole." | 7.96 | Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals. ( Beck, KR; Odermatt, A; Telisman, L; Thompson, GR; van Koppen, CJ, 2020) |
"Vascular function, including reactive hyperemia index (RHI), flow-mediated vasodilation (FMD) and nitroglycerine-induced vasodilation (NID), arterial stiffness including brachial-ankle pulse wave velocity (baPWV) and brachial intima-media thickness (IMT) and ROCK activity in peripheral leukocytes were measured before and after 12 weeks of treatment with eplerenone in 50 patients with IHA." | 7.91 | Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study. ( Aibara, Y; Chayama, K; Goto, C; Hashimoto, H; Higashi, Y; Kajikawa, M; Kihara, Y; Kishimoto, S; Liao, JK; Maruhashi, T; Matsui, S; Nakashima, A; Noma, K; Oki, K; Takaeko, Y; Yusoff, FM, 2019) |
" We report our long-term single-practice experience in 5 patients with chronic hyperaldosteronism (HA, including 3 with glucocorticoid remediable aldosteronism, GRA) treated with low-dose amiloride (a specific epithelial sodium channel [ENaC] blocker) 5-10 (mean 7) mg daily for 14-28 (mean 20) years." | 7.91 | Long-term BP control and vascular health in patients with hyperaldosteronism treated with low-dose, amiloride-based therapy. ( Hong, M; Hussain, T; Izzo, JL; Osmond, PJ, 2019) |
"The Captopril challenge test (CCT) is an easy-conduct confirmatory test for diagnosing primary aldosteronism (PA)." | 7.91 | The captopril challenge test for diagnosing primary Aldosteronism in a Chinese population. ( Feng, WH; Li, HY; Li, P; Zhang, WJ; Zhang, Y; Zhu, DL; Zhu, KY, 2019) |
" We report our long-term single-practice experience in an unusual group of five patients with chronic hyperaldosteronism (HA, including three with glucocorticoid-remediable aldosteronism, GRA) treated with low-dose amiloride (a specific epithelial sodium channel [ENaC] blocker) 5-10 (mean 7) mg daily for 14-28 (mean 20) years." | 7.91 | Maintenance of long-term blood pressure control and vascular health by low-dose amiloride-based therapy in hyperaldosteronism. ( Hong, M; Hussain, T; Izzo, JL; Osmond, PJ, 2019) |
"High salt intake markedly enhances hypertension induced by angiotensin II (Ang II)." | 7.88 | Central and peripheral slow-pressor mechanisms contributing to Angiotensin II-salt hypertension in rats. ( Ahmad, M; Blaustein, MP; Hamlyn, JM; Keshtkar-Jahromi, M; Leenen, FHH; Lu, J; Wang, HW, 2018) |
"In the PATHWAY-2 study of resistant hypertension, spironolactone reduced blood pressure substantially more than conventional antihypertensive drugs." | 7.88 | Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies. ( Brown, MJ; Caulfield, MJ; Cruickshank, JK; Ford, I; MacDonald, TM; Mackenzie, IS; McInnes, GT; Morant, SV; Padmanabhan, S; Salsbury, J; Sever, P; Webb, DJ; Williams, B, 2018) |
"Stroke-prone spontaneously hypertensive (SHRSP) rats were administered losartan, amlodipine or saline for 6 or 16weeks at the onset of prehypertension." | 7.85 | Early treatment with losartan effectively ameliorates hypertension and improves vascular remodeling and function in a prehypertensive rat model. ( He, DH; Lin, JX; Xie, Q; Xu, CS; Zhang, LM, 2017) |
"Activation of angiotensinergic pathways by central aldosterone (Aldo)-mineralocorticoid receptor (MR) pathway plays a critical role in angiotensin II (Ang II)-induced hypertension." | 7.83 | Mineralocorticoid and angiotensin II type 1 receptors in the subfornical organ mediate angiotensin II - induced hypothalamic reactive oxygen species and hypertension. ( Ahmad, M; Chen, A; Huang, BS; Leenen, FH; Wang, HW; White, RA, 2016) |
"Cross-sectional data of the single-center "Eplerenone in Primary Hyperparathyroidism" trial were used." | 7.83 | Parathyroid hormone, aldosterone-to-renin ratio and fibroblast growth factor-23 as determinants of nocturnal blood pressure in primary hyperparathyroidism: the eplerenone in primary hyperparathyroidism trial. ( Belyavskiy, E; Brandenburg, VM; Brussee, H; Catena, C; Fahrleitner-Pammer, A; Gaksch, M; Grübler, MR; März, W; Meinitzer, A; Perl, S; Pieske, B; Pilz, S; Scharnagl, H; Sechi, LA; Tomaschitz, A; Van Ballegooijen, AJ; Verheyen, N; Wetzel, J, 2016) |
"Among patients with essential hypertension, circulating endogenous ouabain and Aldo are typically coelevated and their BP is salt-sensitive." | 7.83 | Endogenous ouabain and aldosterone are coelevated in the circulation of patients with essential hypertension. ( Brioni, E; Casamassima, N; Hamlyn, JM; Lanzani, C; Manunta, P; Messaggio, E; Simonini, M; Tentori, S; Zagato, L, 2016) |
" Anthropometric parameters and aldosterone, plasma renin activity, cortisol, cortisone, Homeostasis Model Assessment Insulin Resistance (HOMA-IR), high-sensitivity C-reactive protein, adiponectin, IL-6, plasminogen activator inhibitor type 1 levels and matrix metalloproteinase-9 and matrix metalloproteinase-2 (MMP-9 and MMP-2) activities were measured." | 7.83 | Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension. ( Aglony, M; Allende, F; Bancalari, R; Baudrand, R; Campino, C; Carvajal, CA; Fardella, CE; Fuentes, CA; García, H; García, L; Kalergis, AM; Lagos, CF; Loureiro, C; Martinez-Aguayo, A; Sanhueza, S; Solari, S; Tapia-Castillo, A; Valdivia, C; Vecchiola, A, 2016) |
" In this study, we sought to determine if renal denervation (RDN) inhibits aldosterone expression and associated cardiovascular pathophysiological changes in angiotensin II (Ang II)-induced hypertension." | 7.83 | Renal denervation attenuates aldosterone expression and associated cardiovascular pathophysiology in angiotensin II-induced hypertension. ( Chen, DR; Chen, J; Gao, PJ; Hong, MN; Li, XD; Ma, Y; Ruan, CC; Wu, YJ; Xu, JZ; Zhu, DL, 2016) |
"The objective of this article is to measure serum dehydroepiandrosterone sulfate (DHEA-S) concentration in both genders with primary aldosteronism (PA)." | 7.81 | Serum dehydroepiandrosterone sulfate concentration is lower in women with primary aldosteronism. ( Chen, AH; Huang, TS; Li, HY; Lin, YH; Wu, VC, 2015) |
"The renal mechanisms responsible for angiotensin II (ANG II)-induced hypertension remain incompletely understood." | 7.81 | Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension. ( Li, XC; Miguel-Qin, E; Shull, GE; Zhuo, JL, 2015) |
" This study suggests that telmisartan (TEL) can inhibit myocardial fibrosis of hypertensive left ventricular hypertrophy (LVH) through the transforming growth factor-β1 (TGF-β1)/Smad signaling pathway." | 7.80 | Telmisartan delays myocardial fibrosis in rats with hypertensive left ventricular hypertrophy by TGF-β1/Smad signal pathway. ( Guan, G; Ma, A; Shao, L; Tian, G; Wang, J; Wang, Y; Zhang, Y, 2014) |
" On day 11, hypertension was induced by continuous angiotensin II infusion." | 7.80 | M-atrial natriuretic peptide and nitroglycerin in a canine model of experimental acute hypertensive heart failure: differential actions of 2 cGMP activating therapeutics. ( Burnett, JC; Cataliotti, A; Chen, HH; Ichiki, T; McKie, PM; Sangaralingham, SJ, 2014) |
" We investigated the effects of upregulating heme-oxygenase (HO) on myocardial histo-pathological lesions, proinflammatory cytokines/chemokines, oxidative mediators and important markers of heart failure such as osteopontin and osteoprotergerin in N(ω)-nitro-l-arginine methyl ester (L-NAME)-induced hypertension." | 7.80 | Heme oxygenase suppresses markers of heart failure and ameliorates cardiomyopathy in L-NAME-induced hypertension. ( Chibbar, R; Lane, N; Ndisang, JF, 2014) |
"Aim of the study is to evaluate the impact of spironolactone (SPL) on indexes of metabolic syndrome (MS) and further investigate the mechanisms underlying its protective effects." | 7.79 | Spironolactone prevents dietary-induced metabolic syndrome by inhibiting PI3-K/Akt and p38MAPK signaling pathways. ( Liang, LY; Lin, YE; Liu, MJ; Long, HD; Zeng, ZH, 2013) |
"This study was performed to determine the characteristics and mechanism of hypertension in SHR/NDmcr-cp(+/+) rats (SHRcp), a new model of metabolic syndrome, with a focus on the autonomic nervous system, aldosterone, and angiotensin II." | 7.79 | Novel mechanism for disrupted circadian blood pressure rhythm in a rat model of metabolic syndrome--the critical role of angiotensin II. ( Kataoka, K; Katayama, T; Kim-Mitsuyama, S; Koibuchi, N; Maeda, M; Matsui, K; Mingjie, M; Nakagawa, T; Ogawa, H; Sueta, D; Toyama, K; Uekawa, K; Waki, H; Yasuda, O, 2013) |
"Circulating angiotensin II (Ang II) activates a central aldosterone-mineralocorticoid receptor neuromodulatory pathway, which mediates most of the Ang II-induced hypertension." | 7.79 | Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension. ( Ahmad, M; Huang, BS; Leenen, FH; White, RA, 2013) |
"Leptin and aldosterone have been associated with the pathophysiological mechanisms of hypertension." | 7.79 | High-circulating leptin levels are associated with increased blood pressure in uncontrolled resistant hypertension. ( Barbaro, NR; de Faria, AP; de Haro Moraes, C; Demacq, C; Ferreira-Melo, SE; Figueiredo, VN; Júnior, HM; Martins, LC; Quinaglia, T; Sabbatini, AR, 2013) |
" We report a case of 55-year-old man with primary aldosteronism (PA) whose hyperaldosteronism was suppressed with the PPAR γ agonist pioglitazone." | 7.79 | Suppression of primary aldosteronism and resistant hypertension by the peroxisome proliferator-activated receptor gamma agonist pioglitazone. ( Harada, E; Kashiwagi, Y; Mizuno, Y; Morita, S; Shono, M; Yano, M; Yasue, H; Yoshimura, M, 2013) |
"In 205 patients with untreated essential hypertension, we measured components of the renin-angiotensin-aldosterone system, plasma levels of fibrinogen, D-dimer, prothrombin fragment 1 + 2 (F1 + 2), and plasminogen activator inhibitor-1 (PAI-1), and assessed cardiac characteristics with standard echocardiography." | 7.79 | Association of aldosterone with left ventricular mass in hypertension: interaction with plasma fibrinogen levels. ( Catena, C; Colussi, G; Sechi, LA; Valeri, M, 2013) |
" In the present study, we investigated the contribution of aldosterone to the renal p21 expression and senescence during the development of angiotensin II (AngII)-induced hypertension." | 7.78 | Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice. ( Deguchi, K; Hitomi, H; Kitada, K; Kobori, H; Lei, B; Masaki, T; Minamino, T; Mori, H; Nakano, D; Nishiyama, A, 2012) |
"The aim of this paper is to report a case of unilateral PA with spontaneous remission and reduction of cardiac hypertrophy after long-term spironolactone (SP) therapy." | 7.78 | Unilateral primary aldosteronism with spontaneous remission after long-term spironolactone therapy. ( Demura, M; Karashima, S; Kometani, M; Takata, H; Takeda, Y; Yamagishi, M; Yoneda, T, 2012) |
"The finding of adipocyte-derived hormone leptin as an overstimulator of sympathetic activity brought a new perspective to the pathophysiological mechanisms of obesity-hypertension." | 7.78 | Leptin and aldosterone in sympathetic activity in resistant hypertension with or without type 2 diabetes. ( Boer-Martins, L; Demacq, C; Faria, AP; Figueiredo, VN; Martins, LC; Moraes, Cde H; Moreno, H, 2012) |
" Determination of metanephrines by high-pressure liquid chromatography has been well established for the diagnosis of pheochromocytomas, demonstrating high sensitivity and specificity." | 7.78 | Plasma and urinary metanephrines determined by an enzyme immunoassay, but not serum chromogranin A for the diagnosis of pheochromocytoma in patients with adrenal mass. ( Deutschbein, T; Hinrichs, J; Mann, K; Petersenn, S; Schmidt, H; Unger, N; Walz, MK, 2012) |
"To study on the difference of plasma renin activity (PRA), angiotensin II (Ang II), and aldosterone levels in patients with essential hypertension (EH) or primary aldosteronism (PA) or pheochromocytoma (PHEO), and to analyze the sensitivity and specificity on the diagnosis of PA among patients with hypertension with aldosterone/PRA ratio (ARR)." | 7.78 | [Differences of blood plasma renin activity, angiotensin II and aldosterone levels in essential or secondary hypertension]. ( Chen, S; Fu, CL; Li, M; Lu, L; Song, AL; Sun, ML; Tong, AL; Wang, YH; Zeng, ZP, 2012) |
"Many studies have implicated both angiotensin II (ANG II) and aldosterone (Aldo) in the pathogenesis of hypertension, the progression of renal injury, and cardiac remodeling after myocardial infarction." | 7.77 | Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension. ( Beltz, TG; Gomez-Sanchez, CE; Guo, F; Hay, M; Johnson, AK; Xue, B; Yu, Y, 2011) |
"Hypertension was induced in cyp1a1ren-2 transgenic rats by feeding indole-3-carbinol (n = 10) and in Fischer 344 rats by subcutaneously infusing ANG II (n = 7)." | 7.77 | Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome. ( Clemetson, KJ; Gebhard, S; Gesell-Salazar, M; Greinacher, A; Hammer, E; Kuttler, B; Peters, B; Peters, J; Rettig, R; Scharf, C; Steil, L; Völker, U, 2011) |
" In the present study, the effect of a subdose of fasudil, a selective ROCK inhibitor, on systemic hypertension and myocardium fibrosis induced by aldosterone was investigated in uninephrectomized Sprague-Dawley rats (SD)." | 7.77 | Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats. ( Guo, P; Masaki, T; Mori, H; Nishiyama, A; Wu, C, 2011) |
" It has been reported that eplerenone has a potential antihypertensive effect, with a profile slightly different from that of spironolactone, and has fewer adverse reactions, suggesting that it may become a first-line treatment for hypertension." | 7.76 | Clinical effects of eplerenone, a selective aldosterone blocker, in Japanese patients with essential hypertension. ( Fukuda, S; Sato, A, 2010) |
"We, therefore compared, head-to-head, the aldosterone-renin ratio based on PRA with that based on DRA, at baseline and after captopril administration, for identifying aldosterone-producing adenoma (APA) in 251 patients of the Primary Aldosteronism Prevalence in hYpertension Study (PAPY)." | 7.76 | The aldosterone-renin ratio based on the plasma renin activity and the direct renin assay for diagnosing aldosterone-producing adenoma. ( Barisa, M; Belfiore, A; Desideri, G; Ferri, C; Letizia, C; Maccario, M; Mantero, F; Morganti, A; Palumbo, G; Patalano, A; Pessina, AC; Roman, E; Rossi, GP; Seccia, TM, 2010) |
" The current study was designed to advance our understanding of the therapeutic potential of M-ANP in a canine model of acute angiotensin II-induced hypertension with elevated cardiac filling pressures and aldosterone activation." | 7.76 | A novel atrial natriuretic peptide based therapeutic in experimental angiotensin II mediated acute hypertension. ( Boerrigter, G; Burnett, JC; Cataliotti, A; Chen, HH; Ichiki, T; Martin, FL; McKie, PM; Sangaralingham, SJ, 2010) |
" To elucidate the potential role of local renin-angiotensin system in aldosterone-induced cardiovascular injury, we investigated the effects of selective mineralocorticoid receptor (MR) antagonist eplerenone (EPL), angiotensin (Ang) II type 1 receptor antagonist candesartan (ARB), and superoxide dismutase mimetic tempol (TEM) on the development of hypertension, vascular injury, oxidative stress, and inflammatory-related gene expression in aldosterone-treated hypertensive rats." | 7.74 | Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: the possible role of local renin-angiotensin system. ( Hirata, Y; Hirono, Y; Kobayashi, N; Sakurada, M; Shichiri, M; Sugiyama, T; Suzuki, N; Takai, S; Yoshimoto, T, 2007) |
" To elucidate its significance for myocardial fibrosis in the hypertensive heart, we used a mouse model with infusion of angiotensin II and examined results by histology, immunohistochemistry, in situ hybridization, and quantitative real-time reverse transcriptase polymerase chain reaction (RT-PCR)." | 7.74 | Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation. ( Hiroe, M; Imanaka-Yoshida, K; Inada, H; Nishioka, T; Onishi, K; Suzuki, M; Takakura, N; Yoshida, T, 2007) |
"Renin-angiotensin system gene polymorphisms are associated with essential hypertension; angiotensinogen gene variants are considered potential genetic risk factors." | 7.74 | Significance of angiotensinogen gene haplotypes and genotypes combinations in hypertension. ( Goyal, AK; Gupta, M; Javed, S; Kumar, R; Nejatizadeh, A; Pasha, MQ; Stobdan, T, 2008) |
"To compare efficacy of use of the blocker of aldosteron receptors spironolactone and diuretic indapamide in low-renin arterial hypertension (AH), their action on blood pressure, serum concentrations of sodium, potassium, creatinine, plasmic renin activity (PRA), plasmic aldosteron concentration (PAC)." | 7.73 | [Use of spironolactone and indapamide in the treatment of low-renin arterial hypertension]. ( Bagdonas, G; Kazanavichus, G; Naudzhunas, A; Yankauskene, L, 2006) |
" Since chronic inhibition of nitric oxide (NO) synthase with N(omega)-nitro-L-arginine methyl ester (L-NAME) induces systemic hypertension associated with cardiovascular inflammation and remodeling, we examined the potential role of aldosterone in this process using eplerenone, a selective aldosterone receptor antagonist." | 7.73 | The antagonism of aldosterone receptor prevents the development of hypertensive heart failure induced by chronic inhibition of nitric oxide synthesis in rats. ( Asano, Y; Fujita, M; Hirata, A; Hori, M; Kitakaze, M; Minamino, T; Okada, K; Sanada, S; Shintani, Y; Takashima, S; Tomoike, H; Tsukamoto, O; Yamasaki, S; Yulin, L, 2006) |
"Losartan attenuates BSO-induced hypertension, which appears to be mediated, in part, by angiotensin II and the prostanoid endothelium-derived factors." | 7.72 | Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats. ( Abukhalaf, IK; Bayorh, MA; Eatman, D; Ganafa, AA; Silvestrov, N; Socci, RR, 2003) |
"The effects of low-dose oral spironolactone (SPIRO) in a rat model of hypertensive heart failure (spontaneously hypertensive heart failure rat) were compared with its effects when combined with captopril (CAP)." | 7.72 | Combined effects of low-dose oral spironolactone and captopril therapy in a rat model of spontaneous hypertension and heart failure. ( Bauer, JA; Ghosh, S; Holycross, BJ; Kambara, A; Kwiatkowski, P; McCune, SA; Schanbacher, B; Wung, P, 2003) |
"We investigated the pathophysiological role of the cardiac adrenomedullin (AM) system, including the ligand, receptor and amidating activity in the hypertrophied heart in severe hypertension." | 7.72 | Upregulation of ligand, receptor system, and amidating activity of adrenomedullin in left ventricular hypertrophy of severely hypertensive rats: effects of angiotensin-converting enzyme inhibitors and diuretic. ( Akimoto, K; Minamino, N; Mori, Y; Nishikimi, T; Tadokoro, K; Wang, X, 2003) |
"Functional changes in the kidneys of healthy men with (FH+) (n = 15) and without (FH-) (n = 15) family history of primary arterial hypertension were examined during administration of low-dose exogenous angiotensin II (A2) (1 ng/kg per min) before and after acute (1 mg intravenous enalaprilat) and chronic (7 days oral enalapril, 30 mg/day) angiotensin-converting enzyme (ACE) inhibition." | 7.72 | Increased renovascular response to angiotensin II in persons genetically predisposed to arterial hypertension disappears after chronic angiotensin-converting enzyme inhibition. ( Bock, A; Dieterle, T; Drewe, J; Gyr, K; Haberthür, C; Huber, PR; Martina, B; Schächinger, H, 2004) |
"There are not studies about the utility of modified liberation doxazosin (MLD) in the combined treatment of the true resistant hypertension (TRH)." | 7.72 | [Effect of modified liberation doxazosin on blood pressure, insulin resistance, and catecholamine secretion in patients with true resistant hypertension]. ( Aliaga Martínez, L; Fernández-Torres, C; Jiménez-Alonso, J; Mediavilla García, JD; Sabio, JM, 2004) |
"The dual ACE+NEP inhibitor MDL prevented and regressed severe hypertension and cardiovascular damage, even in this model of severe angiotensin II-dependent hypertension with pronounced cardiovascular damage." | 7.71 | Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor. ( Agabiti-Rosei, E; Bova, S; Cavallin, M; Mazzocchi, G; Nussdorfer, GG; Pessina, AC; Rizzoni, D; Rossi, GP, 2002) |
"Aldosterone-induced hypertension is associated with renal damage that may be mediated by endothelin-1 (ET-1)." | 7.71 | Contribution of endothelin-1 to renal activator protein-1 activation and macrophage infiltration in aldosterone-induced hypertension. ( Chen, X; He, G; Schiffrin, EL; Tostes, RC; Touyz, RM, 2002) |
"The aim of the study was to compare hypotensive reaction after treatment with enalapril and enalapril with isosorbide mononitrate in patients with mild and moderate hypertension." | 7.71 | [Effect of isosorbide mononitrate on hypotensive action of enalapril in patients with mild and moderate hypertension]. ( Przewłocka-Kosmala, M, 2002) |
"An increased sensitivity to angiotensin II (Ang II) has been observed in patients with established hypertension." | 7.71 | Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension. ( Delles, C; Jacobi, J; Klingbeil, AU; Schlaich, MP; Schmidt, BM; Schmieder, RE; Schneider, MP, 2002) |
"Spironolactone is a safe, effective therapy for patients with refractory hypertension." | 7.71 | The role of spironolactone in the treatment of patients with refractory hypertension. ( Carré, E; Lincoff, AM; Mertes, M; Ouzan, J; Pérault, C, 2002) |
" The antistroke effects of captopril treatment occurred without an antihypertensive effect, weren't altered by enhancing hypertension during treatment (with dexamethasone), and couldn't be duplicated by antihypertensive treatment with hydralazine." | 7.70 | Effect of poststroke captopril treatment on mortality associated with hemorrhagic stroke in stroke-prone rats. ( King, SR; Smeda, J; Vasdev, S, 1999) |
"Clinical evaluation of hypotensive effectiveness and the cardiovascular and side effects of enalapril monotherapy of significant essential hypertension (SEH) in adolescents was performed." | 7.69 | [Evaluation of the efficacy and safety of monotherapy for significant essential hypertension in adolescents with use of enalapril]. ( Cichocka, E; Januszewicz, P; Kawalec, W; Wyszyńska, T, 1995) |
"Flosequinan (BTS 49465, 7-fluoro-1-methyl-3-methyl-sulphinyl-4-quinolone), a recently direct-acting vasodilator that should cause relatively less reflex tachycardia, was given in a single oral dose of 200 mg to 10 untreated patients with moderate to severe hypertension." | 7.69 | Acute effects of flosequinan (BTS 49465) in untreated moderate to severe hypertension. ( Janssen, MC; Reyenga, J; Smits, P; Thien, T, 1995) |
"Ten cases of adrenal adenomas, one case with unilateral adrenal hyperplasia, and another case with apparent bilateral are reported, in whom an alternative pathway of aldosterone via 21-deoxyaldosterone is operative." | 7.69 | A new subset of mineralocorticoid hypertension with excess of 21-deoxyaldosterone and Kelly's-M1 steroid: clinical and morphological findings. ( Abdelhamid, S; Bönhof, JA; Haack, D; Lewicka, S; Müller-Lobeck, H; Nensel, U; Pahl, S; Remberger, K; Röckel, A; Vecsei, P, 1995) |
" To define possible cellular mechanisms involved in central mineralocorticoid action, benzamil, an amiloride analogue with selective affinity for the Na+ channel, was continuously infused intracerebroventricularly in three mineralocorticoid-dependent hypertension models in Sprague-Dawley rats, the continuous subcutaneous infusion of aldosterone, the intracerebroventricular infusion of aldosterone, and the ingestion of carbenoxolone, a synthetic licorice analogue." | 7.69 | Effect of central amiloride infusion on mineralocorticoid hypertension. ( Gomez-Sanchez, CE; Gomez-Sanchez, EP, 1994) |
" Study 1: A long-term (4 weeks) treatment with slow-release nifedipine (Nif), 40-60 mg/day, was performed in 9 in-patients with essential hypertension (EHT)." | 7.69 | [Mechanism of inhibition of aldosterone secretion by a Ca2+ channel blocker in patients with essential hypertension and patients with primary aldosteronism]. ( Iimura, O; Shimamoto, K; Yokoyama, T, 1995) |
"Approximately half of Caucasian patients with essential hypertension and with hyperaldosteronism exhibit elevated circulating levels of endogenous ouabain." | 7.69 | Immunoreactive endogenous ouabain in primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels. ( De Toni, R; Hamlyn, JM; Manunta, P; Pavan, E; Pessina, AC; Rossi, G; Semplicini, A, 1995) |
"The present study aimed to assess the influence of a highly industrialized environment on the prevalence of arterial hypertension and plasma levels of cholesterol, uric acid, aldosterone and plasma renin activity." | 7.69 | Does industrial environment influence the prevalence of arterial hypertension, plasma cholesterol and uric acid concentration and activity of the renin-aldosterone system? ( Kokot, F; Wiecek, A, 1996) |
" Tsukuba hypertensive mice (THM) carry both human renin and angiotensinogen genes, and develop hypertension." | 7.69 | Development of polyuria in Tsukuba hypertensive mice carrying human renin and angiotensinogen genes. ( Fukamizu, A; Ikemoto, F; Mino, N; Murakami, K; Nishikibe, M; Tsuchida, M; Uehara, S, 1995) |
"Myocardial fibrosis, associated with increased expression of angiotensin converting enzyme (ACE) and bradykinin (BK) receptor binding at sites of tissue repair, accompanies chronic elevations in circulating angiotensin II (AngII) and/or aldosterone (ALDO) that simulate chronic cardiac failure." | 7.69 | Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion. ( Ramires, FJ; Sun, Y; Weber, KT, 1997) |
"We have investigated the possible involvement of endogenous corticosteroids in the maintenance of hypertension in aged lean and obese Zucker rats using the type II corticosteroid antagonist mifepristone." | 7.69 | Effects of the glucocorticoid II receptor antagonist mifepristone on hypertension in the obese Zucker rat. ( Clapham, JC; Turner, NC, 1997) |
"The present study was designed to investigate the effect of L-arginine administration on patients with essential and secondary hypertension by measuring haemodynamic parameters, neuroendocrine hormones and indicators of nitric oxide (NO) release." | 7.68 | Role of L-arginine-nitric oxide pathway in hypertension. ( Hishikawa, K; Kato, R; Nakaki, T; Saruta, T; Suzuki, H, 1993) |
"Vascular permeability of the coronary and mesenteric circulation is increased in association with the arterial hypertension that accompanies either endogenous activation of the renin-angiotensin-aldosterone system (RAAS) or exogenous administration of angiotensin II (AII)." | 7.68 | Coronary microvascular fluid flux and permeability: influence of angiotensin II, aldosterone, and acute arterial hypertension. ( Campbell, SE; Janicki, JS; Reddy, HK; Weber, KT; Zhou, G, 1993) |
"A case of primary aldosteronism treated with spironolactone therapy has been followed up for 24 years." | 7.68 | Twenty-four year spironolactone therapy in an aged patient with aldosterone-producing adenoma. ( Hashimoto, T; Ito, Y; Koshida, H; Miyamori, I; Morimoto, S; Morise, T; Takeda, R; Yamazaki, T, 1992) |
"The effect of manidipine on cardiac hypertrophy, coronary circulation, left ventricular weight and maximal coronary flow in hypertension was measured in DOCA/salt treated systolic hypertensive rats with and without manidipine treatment." | 7.68 | Effect of manidipine on cardiac hypertrophy and coronary circulation in DOCA/salt hypertensive rats. ( Asayama, J; Itoh, H; Kuwabara, T; Nakagawa, M; Nakata, T; Sasaki, S; Takeda, K; Takesako, T; Tanabe, S; Yamahara, Y, 1992) |
"The effect of treatment of hypertension with nifedipine on plasma renin activity, blood serum level of aldosterone in the course of renin test, and cortisol and growth hormone concentrations after stimulation with insulin hypoglycemia was followed during two weeks of treatment in 40 patients with essential hypertension." | 7.68 | [Effect of nifedipine treatment on the renin-aldosterone system and secretion of cortisol and growth hormone in patients with essential hypertension]. ( Kokot, F; Wnuk, R, 1991) |
"To clarify the hemodynamic and endocrine mechanisms of the hypotensive effect of amosulalol, an alpha- and beta-adrenoceptor antagonist, 19 patients with essential hypertension received amosulalol (20-80 mg/day; average 48." | 7.68 | Hemodynamic and endocrine changes associated with hypotensive action of amosulalol in essential hypertension. ( Ando, K; Fujita, T; Noda, H; Ogata, E, 1992) |
"Aim of this study was to assess the relationship between plasma concentration of atrial natriuretic factor (ANF) and its two-dimensional echocardiographic (left ventricular mass, left atrium diameter) and humoral (plasma renin and aldosterone) variables in essential hypertension (EH)." | 7.68 | Atrial natriuretic factor in essential hypertension: echocardiographic and humoral correlates. ( Favilla, S; Lattanzi, F; Lucarini, AR; Marini, C; Salvetti, A; Urbani, MP, 1992) |
"This study was conducted to elucidate renal uric acid metabolism in patients with primary aldosteronism (PA;16 cases) as compared with normotensive subjects (NT;25 cases) and essential hypertensives (EHT;51 cases)." | 7.68 | [Study on uric acid metabolism in patients with primary aldosteronism]. ( Iimura, O; Kikuchi, K; Komura, H; Marusaki, S; Namba, M; Ohtomo, T; Satoh, N; Suzuki, S; Takada, T, 1992) |
"Urinary excretion of 18-hydroxycortisol (18-OHF), 18-hydroxycorticosterone (18-OHB) and aldosterone 18-glucuronide (Aldo-18-glu) was measured in 10 patients with primary aldosteronism; 5 with aldosterone-producing adenoma (APA) and 5 with idiopathic hyperaldosteronism (IHA), 10 patients with essential hypertension (EHT) and 11 normotensive subjects." | 7.68 | Determination of urinary 18-hydroxycortisol in the diagnosis of primary aldosteronism. ( Iki, K; Itoh, Y; Miyamori, I; Takasaki, H; Takeda, R; Takeda, Y, 1992) |
"Plasma concentrations of renin and aldosterone were measured before and 60 min after taking 25 mg captopril in 242 patients with arterial hypertension (124 men, 118 women, aged 51." | 7.68 | [Does the captopril test improve the diagnosis of primary hyperaldosteronism?]. ( Bönner, G; Degenhardt, S; Grimm, U; Krone, W; Stimpel, M; Wambach, G, 1992) |
" In 10 patients with essential hypertension, we investigated the influence of betaxolol, a selective beta 1-adrenergic blocking agent, on renal function and on plasma levels of ANP during exercise, volume depletion and volume expansion." | 7.68 | Influence of betaxolol on renal function and atrial natriuretic peptide in essential hypertension. ( Grabensee, B; Heering, P; Hollenbeck, M; Kutkuhn, B; Plum, J, 1991) |
"Plasma levels of atrial natriuretic factor were measured in 71 patients with essential hypertension and 13 with borderline arterial hypertension by using radioimmunoassay." | 7.68 | [Atrial natriuretic factor in patients with hypertension]. ( Bil'chenko, AV; Vasil'ev, IuM, 1991) |
"130 cases of patients with essential hypertension (EH) and 70 cases of normal subjects were researched for correlation between TCM differential types and plasma levels of renin, angiotension II, aldosterone, atrial natriuretic factor (ANF) in patients with EH." | 7.68 | [Relation between traditional Chinese medicine differential types and plasma levels of renin, angiotension II, aldosterone, atrial natriuretic factor in patients with essential hypertension]. ( Li, H, 1991) |
"Plasma levels of atrial natriuretic peptide (ANP) were measured in patients with normal renin essential hypertension (n = 12), low renin essential hypertension (n = 11) and primary aldosteronism due to aldosterone producing adenoma (APA, n = 8) and idiopathic hyperaldosteronism (IHA, n = 3) after overnight rest in the supine position and after 4 h upright posture and furosemide administration." | 7.68 | Dissociation of plasma atrial natriuretic peptide responses to upright posture and furosemide administration in patients with normal-, low renin essential hypertension and primary aldosteronism. ( Fütö, L; Gláz, E; Gutkowska, J; Kiss, R; Rácz, K; Sergev, O; Varga, I, 1991) |
"To study the effects of a novel angiotensin I converting enzyme inhibitor (ACEI) on hypertension-induced cardiac hypertrophy, benazepril hydrochloride (CGS 14824 A, CAS 86541-74-4) at the dose of 3 and 10 mg/kg/d p." | 7.68 | Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneously hypertensive rats. ( Hasegawa, Y; Inukai, T; Katahira, J; Nakao, K; Takemori, E, 1991) |
"0% by weight) of the neutral amino acid, L-tryptophan, on the development of hypertension during chronic exposure to cold." | 7.68 | Effect of chronic dietary treatment with L-tryptophan on the development of cold-induced hypertension in rats. ( Baron, A; Cade, JR; Fregly, MJ; Riesselmann, A, 1991) |
"An attenuation of adrenergic activity during the inhibition of endogenous angiotensin II formation was evaluated by determining plasma norepinephrine concentration after a single oral administration of captopril compared to that after nifedipine in essential hypertension." | 7.68 | Captopril attenuates reflex adrenergic response in essential hypertension. ( Masuyama, Y; Mohara, O, 1991) |
"The effects of the mineralocorticoid antagonist mespirenone on the development and maintenance of aldosterone-induced hypertension in Sprague-Dawley rats has been studied." | 7.68 | Effect of a new mineralocorticoid antagonist mespirenone on aldosterone-induced hypertension. ( Agarwal, M; Kalimi, M; Opoku, J; Qureshi, D, 1991) |
"This case of Conn's syndrome demonstrates long-term (seven years) efficacy of triamterene-thiazide therapy in controlling both hypertension and hypokalemia." | 7.68 | Long-term medical management of aldosterone-producing adenoma. ( Bornemann, M, 1990) |
" They investigated therefore in 15 patients with essential hypertension (EH) and in three patients with pheochromocytoma the urinary excretion of free noradrenaline (NA), adrenaline (A) and dopamine (DA), the plasma renin activity (PRA), the aldosterone concentration (PAC) and atrial natriuretic factor (ANF) in plasma, using radioimmunoanalysis, always before and 24 hours after clonidine administration (Haemiton retardR) by the oral route." | 7.68 | [The effect of clonidine on humoral factors in patients with arterial hypertension]. ( Dvoráková, J; Gregorová, I; Horký, K; Kopecká, J; Poliak, M, 1990) |
"Atrial natriuretic factor (ANF) may play a role in the regulation of the changes of blood volume and vascular reactivity during pregnancy and when pregnancy is complicated by hypertension." | 7.68 | Plasma atrial natriuretic factor levels during normal pregnancy and pregnancy complicated by diabetes mellitus and hypertension. ( Atkinson, AB; McCance, DR; McKnight, JA; Roberts, G; Sheridan, B; Traub, AI, 1990) |
"This study investigated the ability of two diuretics, amiloride and frusemide, to prevent the development of ACTH induced hypertension in conscious sheep." | 7.68 | Amiloride blocks the onset of ACTH-induced hypertension in the sheep. ( Coghlan, JP; Reid, AF; Scoggins, BA; Whitworth, JA, 1990) |
"The plasma aldosterone (A) and desoxycorticosterone (DOCS) levels were measured in 10 patients with primary aldosteronism and in 2 subgroups with low-renin hypertensive disease (LRHD): (1) those with normal adrenal glands++ (n - 11) and (2) those with structural changes in the cortex (n - 11)." | 7.68 | [Plasma mineralocorticoids--aldosterone and desoxycorticosterone-- in patients with"low-renin"arterial hypertension]. ( Bulkina, OS; Gorbacheva, ON; Levitskaia, IuV; Obtrakht, NV; Sokolova, RI; Ustinova, SE, 1990) |
"There is evidence of crucial central nervous system involvement in the pathogenesis of mineralocorticoid-excess salt hypertension, as well as data indicating that corticosterone is the predominant ligand for the type I adrenocorticoid receptor in the brain." | 7.68 | ICV infusion of corticosterone antagonizes ICV-aldosterone hypertension. ( Fort, C; Gómez-Sánchez, EP; Thwaites, D; Venkataraman, MT, 1990) |
"Initial experiments demonstrated that a 1-h infusion of 10 ng/min angiotensin II (ANG II) into rats causes an increase in plasma aldosterone concentration (PAC) and that chronic administration of aldosterone alone to rats on increased sodium intake causes hypertension." | 7.68 | Role of aldosterone in angiotensin II-induced hypertension in rats. ( Fink, GD; Kanagy, NL; Pawloski, CM, 1990) |
"Ten male patients with essential hypertension were studied on a constant diet (100 mEq of sodium daily) while on placebo, immediately following a 20-mg oral dose of nitrendipine, and during 1 week of nitrendipine therapy (10 mg twice daily)." | 7.67 | Renal effects of nitrendipine monotherapy in essential hypertension. ( Barrett, JD; Eggena, P; Golub, MS; Sambhi, MP; Thananopavarn, C, 1984) |
"The converting enzyme inhibitor enalapril, in single daily doses of 10 to 40 mg, was given to 20 hypertensive patients with renal artery stenosis." | 7.67 | Enalapril in treatment of hypertension with renal artery stenosis. Changes in blood pressure, renin, angiotensin I and II, renal function, and body composition. ( Brown, JJ; Cumming, AM; Davies, DL; East, BW; Hodsman, GP; Lever, AF; Morton, JJ; Murray, GD; Robertson, JI, 1984) |
"Enalapril lowers blood pressure both acutely and during long-term therapy in patients with essential hypertension." | 7.67 | Plasma enalapril levels and hormonal effects after short- and long-term administration in essential hypertension. ( Casley, D; Cubella, R; Jackson, BJ; Johnston, CI; Larmour, I, 1984) |
"Forty to fifty percent of patients with essential hypertension are unable to modify their adrenal and renal vascular responses to angiotensin II with changes in sodium intake." | 7.67 | Converting enzyme inhibitors normalize the reduced adrenal responsiveness to angiotensin II in essential hypertension. ( Hollenberg, NK; Williams, GH, 1984) |
"The dependence of arteriolar vasoconstrictor tone on the activity of Na+,K+-ATPase was studied in 17 normotensive subjects (NT) and 28 patients with essential hypertension (EH) by measuring the response in forearm blood flow and vascular resistance to intraarterial infusion of the Na+,K+-ATPase inhibitor ouabain." | 7.67 | Forearm vasoconstrictor response to ouabain: studies in patients with mild and moderate essential hypertension. ( Bolli, P; Bühler, FR; Hulthén, UL; Kiowski, W, 1984) |
" Furthermore, acute and chronic administrations of clonidine were used to determine a participation of the sympathetic nervous system in the maintenance of hypertension in these patients." | 7.67 | Plasma catecholamines and autonomic nervous system function in patients with early renal insufficiency and hypertension: effect of clonidine. ( Campese, VM; Levitan, D; Massry, SG; Romoff, M, 1984) |
"The converting-enzyme inhibitor captopril (25-50 mg orally every 6 h for 66 h) was used to dissociate the circulating levels of angiotensin II (ANG II) from changes in sodium balance in 11 patients with normal renin essential hypertension on 10 mmol of sodium/day intake." | 7.67 | Captopril enhances vascular and adrenal responsiveness to angiotensin II in essential hypertension. ( Dluhy, RG; Gordon, MB; Hollenberg, NK; Koletsky, RJ; LeBoff, MS; Moore, TJ; Williams, GH, 1984) |
"Treatment of fifteen patients with essential hypertension over four weeks using the beta 1-adrenoceptor blocking agent, metoprolol, resulted in a decrease in 24 h urinary excretion of kallikrein and aldosterone along with a decrease in plasma renin activity." | 7.67 | Effect of metoprolol on 24-hour urinary excretion of adrenal steroids and kallikrein in patients with essential hypertension. ( Fritschka, E; Gotzen, R; Kittler, R; Schöneshöfer, M, 1984) |
"Timolol, a non-cardioselective beta-blocking agent, was administered orally after 2 weeks of placebo to 14 patients with essential hypertension for 8 weeks following 1-4 weeks of dose-ranging period." | 7.67 | Effects of timolol on blood pressure, systemic hemodynamics, plasma renin activity, and glomerular filtration rate in patients with essential hypertension. ( Bedogna, V; Fabris, A; Gammaro, L; Maschio, G; Ortalda, V; Tessitore, N; Valvo, E, 1984) |
"Studies were carried out in 15 patients with renal insufficiency and hypertension to compare the long-term effects of methyldopa and propranolol on renal hemodynamics." | 7.67 | Comparison of long-term renal hemodynamic effects of methyldopa and propranolol in patients with hypertension and renal insufficiency. ( Alterman, L; Bank, DE; Bank, N; Lowenstein, I; Zelen, R, 1984) |
"Blood pressure, plethysmographically determined muscle blood flow in the calf at rest and during maximal dilatation, plasma renin activity, angiotensin II and plasma and urinary aldosterone were determined in normotensive men with a positive family history of hypertension (n = 17) and in an age- and weight-matched control group (n = 15) during usual sodium intake and after four weeks of increased salt intake." | 7.67 | Calf muscle haemodynamics and the renin-angiotensin-aldosterone system in normotensive subjects with a familial predisposition to hypertension: changes during increased salt intake. ( Andersson, OK; Aurell, M; Berglund, GL; Gudmundsson, O; Wikstrand, JM, 1984) |
"Aldosterone responses to posture and the dopamine antagonist, metoclopramide, were studied in seven normotensive controls and 12 patients with essential hypertension." | 7.67 | Enhanced response of plasma aldosterone to metoclopramide in essential hypertension. ( Eshkol, A; Lunenfeld, B; Rosenthal, T; Sowers, JR; Stern, N; Tuck, M, 1984) |
"The responsiveness of plasma aldosterone to the infusion of angiotensin II at dose rates of 2, 4, and 10 ng/kg X min was assessed in 11 normal subjects and 13 patients with mild essential hypertension before and after 4 weeks of treatment with the sympatholytic agent debrisoquine." | 7.67 | Relationship between plasma aldosterone and angiotensin II before and after noradrenergic inhibition in normal subjects and patients with mild essential hypertension. ( Beretta-Piccoli, C; Bianchetti, MG; Boehringer, K; Link, L; Morton, JJ; Weidmann, P, 1984) |
"A 46-year-old woman with hypertension, normokalemia, suppressed renin, normal catecholamines, and a left adrenal mass on the CT scan was found to have excessive 18-hydroxycorticosterone (18-OHB) and normal aldosterone levels in plasma, both of which responded poorly to sodium restriction and angiotension II, and supranormally to ACTH." | 7.67 | Adrenal adenoma with 18-hydroxycorticosterone excess and hypertension: a variant of aldosteronomas. ( Azukizawa, S; Hosojima, H; Imaizumi, N; Kigoshi, T; Morimoto, S; Uchida, K; Yamamoto, I, 1984) |
"A single dose of doxazosin, a long-acting postsynaptic alpha 1-adrenoceptor antagonist, was administered to seven patients with essential hypertension." | 7.67 | Antihypertensive effects and pharmacokinetics of single and consecutive administration of doxazosin in patients with mild to moderate essential hypertension. ( Kaneko, Y; Miyajima, E; Miyakawa, T; Shionoiri, H; Takagi, N; Umemura, S; Yasuda, G; Yoshimura, H, 1987) |
"The principal aim of this study was to investigate the effects of ketanserin on peripheral vascular pressor mechanisms in nine patients with essential hypertension, including an assessment of the responsiveness to intravenous infusions of the alpha 1-adrenergic agonist, phenylephrine, and the nonadrenergic vasoconstrictor, angiotensin II." | 7.67 | Effects of ketanserin on peripheral vascular pressor mechanisms in essential hypertension. ( Donnelly, R; Elliott, HL; Reid, JL, 1988) |
" Eight patients with essential hypertension were challenged with an infusion of 32 mmol of potassium chloride in saline before and after control of their blood pressure by the angiotensin converting-enzyme (ACE) inhibitor enalapril." | 7.67 | Effect of angiotensin converting-enzyme inhibition on potassium-mediated aldosterone secretion in essential hypertension. ( Barnes, JN; Drew, PJ; Furniss, SS; Goodwin, FJ; Holly, JM; Knight, AR; Skehan, JD, 1985) |
"Glomerular filtration rate (GFR) and tubular function were measured by means of the lithium clearance technique in 14 patients with renovascular hypertension (RVH) and eight patients with essential hypertension (EH) before and after oral administration of captopril 25 mg." | 7.67 | Abnormal glomerular and tubular function during angiotensin converting enzyme inhibition in renovascular hypertension evaluated by the lithium clearance method. ( Amdisen, A; Danielsen, H; Eiskjaer, H; Hansen, HH; Jensen, FT; Jespersen, B; Madsen, B; Nielsen, HK; Pedersen, EB; Sørensen, SS, 1989) |
"The author reviews contemporary views on the pathogenetic participation of selected humoral factors (of the renin-angiotensin-aldosterone system, natriuretic hormone and atrial natriuretic factor) in the development of arterial hypertension in humans." | 7.67 | [Humoral mechanisms in the pathogenesis of arterial hypertension with emphasis on the renin-angiotensin-aldosterone system and natriuretic substances]. ( Horký, K, 1989) |
"The relationship between atrial natriuretic factor (ANF), the renin-aldosterone axis, and blood pressure reduction with weight loss was investigated in 18 obese subjects (five hypertensive and 13 normotensive) placed on a 12-week, low-sodium (40 mmol), weight-reducing diet." | 7.67 | Weight reduction decreases atrial natriuretic factor and blood pressure in obese patients. ( McMurray, RW; Vesely, DL, 1989) |
"Nine hypertensive patients with mild to moderate renal dysfunction were entered into a protocol to assess the blood pressure, humoral and renal effects of the angiotensin converting enzyme inhibitor, Benazepril (CGS14824A, 2 to 20 mg twice daily) in patients with hypertension and moderate renal insufficiency (mean creatinine clearance 56 ml/min/1." | 7.67 | Effect of benazepril monotherapy in subjects with hypertension associated with renal dysfunction. ( Bauer, JH; Lau, A; Reams, GP, 1989) |
"Effects of a single administration of captopril on plasma and urinary vasopressin (AVP) were examined in 8 normotensive (NT) female volunteers, 17 patients with essential hypertension (EHT) and 2 patients with primary aldosteronism (PA)." | 7.67 | Effect of single-administration captopril on plasma and urinary vasopressin in normotensive subjects and patients with essential hypertension and primary aldosteronism. ( Fujishima, M; Kimura, Y; Muratani, H; Nakao, Y; Takishita, S; Tomita, Y; Tsuchihashi, T; Ueno, M, 1989) |
"In 16 patients with essential hypertension the effects of enalapril 20 mg once daily were compared with those of atenolol 50 mg once daily, with the two drugs in combination and with placebo using a double-blind cross-over design with allocation of treatment order by randomised Latin squares." | 7.67 | Enalapril and atenolol in essential hypertension: attenuation of hypotensive effects in combination. ( Bune, AJ; Cain, MD; Chalmers, JP; Morris, MJ; Russell, AE; Southgate, DO; West, MJ; Wing, LM, 1988) |
"The effects of ovine corticotropin releasing factor (o-CRF) on plasma aldosterone, 18-OH-corticosterone (18-OHB), plasma adrenocorticotropin (ACTH) and cortisol were determined in eight patients with primary aldosteronism, six with aldosterone-producing adenoma (APA) and two with idiopathic hyperaldosteronism (IHA)." | 7.67 | Effects of corticotropin-releasing factor (CRF) on aldosterone and 18-hydroxycorticosterone in essential hypertension and primary aldosteronism. ( Ikeda, M; Koshida, H; Matsubara, T; Miyamori, I; Morise, T; Okamoto, S; Takeda, R; Takeda, Y; Vecsei, P; Yasuhara, S, 1987) |
"This study was designed to examine the mechanisms that contribute to the chronic hypotensive effects of verapamil during angiotensin II-induced hypertension." | 7.67 | Chronic hypotensive effects of verapamil in angiotensin hypertension are steroid independent. ( Lohmeier, TE; Montani, JP; Rushing, EL; Smith, MJ, 1989) |
"Thirteen patients with hypertension and normal renal function received nitrendipine, a calcium entry blocker." | 7.67 | Nitrendipine, a calcium-entry blocker. Renal and humoral effects in human arterial hypertension. ( Bravo, EL; Fouad, FM; Pedrinelli, R; Tarazi, RC; Textor, SC, 1986) |
"To study the effects of Ca antagonists on hypertension induced cardiac and vascular hypertrophy, diltiazem, at the doses of 30 and 60 mg/kg, p." | 7.67 | [Effects of diltiazem on developing blood pressure and accompanying cardiac and vascular hypertrophy in SHR]. ( Inamasu, M; Iwasaki, HO; Morita, T; Nagao, T; Narita, H, 1985) |
" These studies were performed in patients with essential hypertension who were maintained on a constant sodium intake (100 mmol/day), before and after 5 days of treatment with ibopamine, an orally active dopamine analogue." | 7.67 | Dopaminergic control of aldosterone secretion is not mediated by atrial natriuretic factor in patients with essential hypertension. ( Ambrosi, B; Ardeleani, G; Ferraris, P; Morganti, A; Quorso, P; Sala, C; Venegoni, P; Zanchetti, A, 1988) |
" The present study evaluated plasma beta-endorphin, ACTH, cortisol, and aldosterone levels in patients with IHA (n = 10), aldosterone-producing adenomas (n = 4), essential hypertension (n = 11), and normal subjects (n = 10)." | 7.67 | Plasma beta-endorphin levels in primary aldosteronism. ( Berelowitz, B; Griffing, GT; Hudson, M; Manson, JA; McIntosh, T; Melby, JC; Salzman, R, 1985) |
"The purpose of this study was to evaluate the natriuretic effect and renal haemodynamic changes induced by enalapril in patients with essential hypertension." | 7.67 | Natriuretic effect and changes in renal haemodynamics induced by enalapril in essential hypertension. ( Brito, M; Gilbert, HB; Giménez, M; Marcó, E; Moledo, LI; Raffaele, P; Sánchez, RA, 1985) |
"In 15 patients with mild-to-moderate essential hypertension a new orally active angiotensin converting enzyme inhibitor, 1-(D-3-acetylthio-2-methylpropanoyl)-L-prolyl-L-phenylalanine (Alacepril), was administered with a single oral dose of 50 mg to evaluate its antihypertensive effect." | 7.67 | Acute effects of the new oral angiotensin converting enzyme inhibitor 1-(D-3-acetylthio-2-methylpropanoyl)-L-prolyl-L-phenylalanine (Alacepril) in essential hypertension. ( Fukuchi, S; Hashimoto, S; Kunii, N; Mizuno, K; Niimura, S; Tani, M; Watari, H; Yabe, R, 1985) |
"We evaluated the effect of additional chlorthalidone therapy on blood pressure and body fluid volumes in 10 patients with essential hypertension who did not respond to chronic converting enzyme inhibition with enalapril." | 7.67 | Changes in blood pressure and body fluid volumes during diuretic therapy in patients with essential hypertension who receive enalapril. ( Geyskes, GG; Mees, EJ; Roos, JC; van Schaik, BA, 1986) |
"The angiotensin converting enzyme (ACE) inhibitor captopril proved to be an effective antihypertensive drug during a 5-year follow-up study of patients with severe hypertension who had been resistant to a triple-drug regimen." | 7.67 | [Results of a 5-year study with captopril in patients with severe therapy-resistant hypertension]. ( Scheler, F; Schoel, G; Schrader, J, 1986) |
"Nifedipine, in a slow release preparation, was given at a mean daily dosage of 47 +/- 4 mg to 12 patients with severe hypertension in whom arterial pressure was not satisfactorily controlled (mean blood pressure, 172 +/- 6/111 +/- 4 mmHg) by the association of a converting enzyme inhibitor and a diuretic." | 7.67 | Effect of nifedipine in hypertension not controlled by converting enzyme inhibitor and diuretic. ( Mimran, A; Ribstein, J, 1986) |
"0] octane-3-carboxylic acid (ramipril, Hoe 498) were investigated in 10 patients with essential hypertension (WHO stage I or II)." | 7.67 | Humoral and blood pressure effects of the angiotensin converting enzyme inhibitor ramipril in essential hypertension. ( Distler, A; Eckert, HG; Haller, H; Irmisch, R; Lenz, T; Metzger, H; Meyer-Sabellek, W; Philipp, T; Tansey, MJ; Wilp, C, 1986) |
"Captopril effects were studied in 27 patients with second-stage essential hypertension following administration of a single 25 mg oral dose of the drug." | 7.67 | [Mechanisms of the hypotensive action of captopril in essential hypertension]. ( Chernova, NA; Parfenova, EV; Uchitel', IA; Ustinova, SE; Zhukova, IM, 1986) |
"Plasma renin activity (PRA) and plasma aldosterone concentration (PAC) were measured in 19 cases with primary aldosteronism (PA) and 72 with essential hypertension (EHT) to differentiate the two disorders in the following conditions: after overnight recumbency (basal state) and after oral administration of captopril." | 7.67 | Single oral administration of captopril may not bring an improvement in screening of primary aldosteronism. ( Abe, I; Fujishima, M; Kawasaki, T; Kawazoe, N; Muratani, H; Takishita, S; Tomita, Y; Tsuchihashi, T; Ueno, M, 1987) |
"The role of central pressor mechanisms in the maintenance of blood pressure in six hypertensive patients with angiographically proven unilateral renal artery stenosis was investigated by studying the haemodynamic and hormonal responses before and after central sympathetic blockade with clonidine." | 7.67 | Cardiovascular and neurohormonal changes following central sympathetic blockade with clonidine in human unilateral renal artery stenosis. ( Kooner, JS; Mathias, CJ; Peart, S, 1988) |
"The magnitude of captopril hypotensive effect, and variation in renin-angiotensin-aldosterone and kallikrein-kinin parameters were examined in patients with advanced essential hypertension in the presence of normal and low plasma renin activity." | 7.67 | [Changes in the indicators of the renin-angiotensin-aldosterone system, kallikrein-kinin system and arterial blood pressure in elderly patients with essential hypertension treated with captopril]. ( Beuer, E; Brozovskiĭ, KKh; Faulhaber, H; Gurke, R; Khartrodt, V, 1988) |
"We investigated the effect of an orally administered, long-acting, beta-adrenergic blocking agent, penbutolol, on the circadian rhythm of blood pressure (BP) and heart rate (HR), and plasma renin activity (PRA), aldosterone (PA) and cortisol (PC) levels in hospital patients with essential hypertension validated by a chronobiological inferential statistic method." | 7.67 | Effect of penbutolol on circadian blood pressure, and renin, aldosterone and cortisol levels in patients with essential hypertension. ( Bianconi, M; degli Uberti, EC; Margutti, A; Pansini, R; Portaluppi, F; Rossi, R; Teodori, V; Trasforini, G, 1988) |
"The validity of the captopril test for primary aldosteronism (PA) was tested in patients with surgically verified PA (n = 12) or essential hypertension (EHT, n = 20) with different levels of sodium intakes." | 7.67 | Effects of sodium intake on the captopril test for primary aldosteronism. ( Iwaoka, T; Naomi, S; Sato, T; Umeda, T, 1987) |
"In order to evaluate whether changes in the plasma concentration of aldosterone (PA) following the administration of captopril, an inhibitor of angiotensin-converting enzyme, will establish the diagnosis of primary aldosteronism we have used this test in 9 healthy subjects and in 22 patients with various forms of hypertension, including 5 patients with primary aldosteronism due to idiopathic adrenal hyperplasia (n = 4) or aldosterone-producing adenoma (n = 1)." | 7.67 | [Detection of primary aldosteronism using the captopril test]. ( Graninger, W; Nowotny, P; Pirich, K; Vierhapper, H; Waldhäusl, W, 1987) |
"The immediate effects of intravenous diltiazem effects and short-term (4 weeks) of the oral drug on systemic and regional hemodynamics, cardiac structure, and humoral responses were evaluated by previously reported methods in nine patients with mild-to-moderate essential hypertension and in one patient with primary aldosteronism." | 7.67 | Immediate and short-term hemodynamic effects of diltiazem in patients with hypertension. ( Amodeo, C; Frohlich, ED; Kobrin, I; Messerli, FH; Ventura, HO, 1986) |
"The effect of angiotensin converting enzyme inhibition by captopril (CAP) on serum potassium (SK) changes was studied during a three-hour glucose tolerance test (GTT) in recumbent and upright positions in 16 patients with drug-resistant hypertension." | 7.67 | Interplay of various factors in glucose-induced hyperkalemia during captopril treatment. ( Bános, C; Gercsák, G; Radó, JP, 1986) |
"The influence of long-term nifedipine treatment on body fluid compartments, renal function, the renin-angiotensin system, and the adrenergic system was studied in 18 patients with essential hypertension." | 7.67 | Lack of effect of nifedipine on counterregulatory mechanisms in essential hypertension. ( Bruun, NE; Hartling, OJ; Ibsen, H; Moelbak, AG; Nielsen, F; Nielsen, MD, 1986) |
"Plasma renin activity (PRA) and plasma aldosterone concentration (PAC) were measured in 19 cases with primary aldosteronism (PA) and in 72 with essential hypertension (EHT) to differentiate the two disorders during the following conditions on normal salt diet: after overnight recumbency (basal state) and 2 hours after oral administration of 25 mg of captopril." | 7.67 | Is single oral administration of captopril beneficial in screening for primary aldosteronism? ( Abe, I; Kawasaki, T; Kawazoe, N; Kimura, Y; Muratani, H; Takishita, S; Tomita, Y; Tsuchihashi, T; Ueno, M; Uezono, K, 1986) |
"The effect of 8 weeks treatment with the calcium antagonist felodipine--a new long-acting dihydropyridine derivative--in a dose of 10 mg twice daily was studied in 10 male patients with essential hypertension, WHO grade I-II, aged 25-62 years." | 7.67 | The effect of 8 weeks treatment with the calcium antagonist felodipine on blood pressure, heart rate, working capacity, plasma renin activity, plasma angiotensin II, urinary catecholamines and aldosterone in patients with essential hypertension. ( Hökfelt, B; Hulthén, UL; Katzman, PL, 1986) |
"The effect of exogenous angiotensin II on plasma renin activity (PRA), plasma renin concentration (PRC) and plasma aldosterone (PA) was investigated in a group of 8 patients with essential hypertension after one year of captopril therapy." | 7.67 | Effect of exogenous angiotensin II infusion after one year of captopril therapy in essential hypertension. ( Hammond, TG; Miranda, B; Robles, RG; Rodicio, JL; Romero, JC; Ruilope, LM; Sancho, J, 1986) |
"7 years, with systemic systolic hypertension were studied before and after 1 month of therapy with oral hydrochlorothiazide, 50 mg/day." | 7.67 | Systemic systolic hypertension in the elderly: correlation of hemodynamics, plasma volume, renin, aldosterone, urinary metanephrines and response to thiazide therapy. ( Dunsky, MH; Hill, NE; Mookherjee, S; Smulyan, H; Vardan, S; Warner, RA, 1986) |
"Oral administration of felodipine to 10 patients with mild essential hypertension acutely reduced systemic vascular resistance (SVR) by 40% after 30 min." | 7.67 | Acute haemodynamic and humoral responses to felodipine and metoprolol in mild hypertension. ( Amery, A; Fagard, R; Lijnen, P; Moerman, E; Staessen, J, 1987) |
"Plasma concentrations of arginine vasopressin (AVP), angiotensin II (AII), aldosterone (Aldo), urinary output (V), osmolar clearance (Cosm), free water clearance (CH2O), fractional excretions of sodium (FENa) and potassium (FEK), urinary sodium excretion rate (U-Na) and serum potassium (S-K) were determined in 9 patients with essential hypertension (group I) and 13 normotensive healthy control subjects (group II) before and three times during the first 4 hours after an intravenous injection of 40 mg of furosemide." | 7.67 | Abnormal vasopressin and aldosterone response to furosemide in essential hypertension. ( Danielsen, H; Madsen, M; Pedersen, EB; Sørensen, SS; Thomsen, OO, 1986) |
"This study assessed renal sodium handling in a group of patients with essential hypertension in whom control of the renal blood supply and aldosterone release by angiotensin II is abnormal ("non-modulating") because of recent evidence that these patients have sodium-sensitive hypertension." | 7.67 | Abnormal renal sodium handling in essential hypertension. Relation to failure of renal and adrenal modulation of responses to angiotensin II. ( Hollenberg, NK; Moore, T; Rabinowe, S; Redgrave, J; Shoback, D; Williams, GH, 1986) |
"Plasma aldosterone, 18-hydroxycorticosterone (18-OH-B), 18-hydroxydeoxycorticosterone (18-OH-DOC), corticosterone, cortisol and prolactin levels were determined during an angiotensin II infusion at increasing rates both with and without a simultaneous infusion of dopamine in seven normotensive subjects, in ten patients with essential hypertension, and in ten patients with primary aldosteronism." | 7.67 | Dopamine reduces aldosterone and 18-hydroxycorticosterone response to angiotensin II in patients with essential low-renin hypertension and idiopathic hyperaldosteronism. ( Lorenz, R; von Werder, K; Weber, PC; Witzgall, H, 1985) |
"The effects of chronic dietary salt-loading and nifedipine therapy on hypertension-prone (SBH), -resistant (SBN) and parental (SB) Sabra rats were investigated." | 7.67 | Salt-induced hypertension in the 'Sabra' rat strain: influence of nifedipine treatment. ( Ben-Ishay, D; Ebsen, W; Garthoff, B; Kazda, S; Luckhaus, G, 1985) |
"Two patients with hypertension due to coarctation of the aorta were treated for 12 weeks with captopril at increasing doses." | 7.67 | Resistance to captopril in hypertension of coarctation of the aorta. ( Fallo, F; Mantero, F; Maragno, I, 1985) |
"In order to investigate the validity of angiotensin converting enzyme inhibition with captopril as a screening test for primary aldosteronism (PA), 50 mg of captopril were administered orally to 7 patients with PA, 17 with essential hypertension (EH), 5 with renovascular hypertension (RVH), 2 with renoparenchymal hypertension (RH) and 8 normal volunteers." | 7.67 | Clinical evaluation of the captopril screening test for primary aldosteronism. ( Fujii, Y; Hamasaki, S; Inoue, J; Iwaoka, T; Miura, F; Naomi, S; Sato, T; Umeda, T, 1985) |
"Mean arterial blood pressure, forearm vascular resistance, plasma norepinephrine, plasma renin activity and aldosterone responses to graded lower body negative pressure and tilt at 80 degrees were examined in 10 men with mild to moderate essential hypertension before and after 12 weeks of diltiazem (240 to 360 mg/day) therapy." | 7.67 | Effects of diltiazem on hormonal and hemodynamic responses to lower body negative pressure and tilt in patients with mild to moderate systemic hypertension. ( Beck, F; McNamara, C; Mohanty, PK; Sowers, JR; Thames, MD; Welch, B, 1985) |
"The responses of plasma renin activity (PRA), plasma bradykinin (BK) and urinary kallikrein like activity (UK) associated with the infusion of angiotensin II (AII) before and after NaCl loading were investigated in pregnancy induced hypertension (PIH)." | 7.67 | [Studies on the pathophysiology of pregnancy induced hypertension--endocrinological analysis by the method of angiotensin II and NaCl loading]. ( Mochizuki, M; Morikawa, H; Yamasaki, M, 1985) |
"Serum 18-hydroxycorticosterone, aldosterone, and potassium were measured under basal conditions in 34 patients with documented primary aldosteronism, 10 patients with essential hypertension, and 9 normal subjects." | 7.67 | The prediction of anatomical morphology of primary aldosteronism using serum 18-hydroxycorticosterone levels. ( Brown, RD; Hanson, CS; Hollifield, JW; Kem, DC; Painton, R; Tang, K; Weinberger, MH, 1985) |
"Experiments were performed to characterize the hypertension produced by chronic intracerebroventricular (ICV) infusion of angiotensin II (ANG II) in conscious rats." | 7.67 | Sodium-dependent hypertension produced by chronic central angiotensin II infusion. ( Bruner, CA; Fink, GD; Weaver, JM, 1985) |
"In earlier studies by our group it was shown that the urinary tetrahydroaldosterone excretion is a more reliable test for the diagnosis of primary aldosteronism than aldosterone-18-glucuronide ('urinary aldosterone')." | 7.67 | 21-Deoxytetrahydroaldosterone excretion in primary hyperaldosteronism. ( Abdelhamid, S; Lewicka, S; Vecsei, P; Winter, J, 1985) |
"0 mg/kg prizidilol HCl, an antihypertensive with vasodilator and beta-adrenoceptor blocking actions, were given to 12 patients with primary hypertension on separate days." | 7.66 | Prizidilol, an antihypertensive with precapillary vasodilator and beta-adrenoceptor blocking actions, in primary hypertension. ( Karlberg, BE; Larsson, R; Norlander, B; Wirsén, A, 1981) |
"The antihypertensive effect of captopril was tested on 19 patients with essential hypertension, WHO grade I or II." | 7.66 | [Captopril in the treatment of essential hypertension (author's transl)]. ( Braun, B; Klaus, D; Lederle, RM, 1980) |
" The plasma aldosterone responses to exogenous angiotensin II and adrenocorticotropic hormone (ACTH) were studied before and after 1 month of propranolol therapy (120-240 mg/day) in eight patients with essential hypertension." | 7.66 | Effect of propranolol therapy on aldosterone responses to angiotensin II and adrenocorticotropic hormone in essential hypertension. ( Fittingoff, DB; Golub, MS; Tuck, ML, 1981) |
"30% of patients with essential hypertension have a decreased adrenal response to angiotensin II (A II) on a low but not a high sodium intake." | 7.66 | Decreased adrenal responsiveness to angiotensin II: a defect present in spontaneously hypertensive rats. A possible model of human essential hypertension. ( Braley, LM; Menachery, A; Williams, GH, 1982) |
"The humoral and hemodynamic effects of converting enzyme inhibition captopril are presented in two patients with primary hyperaldosteronism (PHA)." | 7.66 | Converting enzyme inhibition with captopril in patients with primary hyperaldosteronism. ( Demers, LM; Harrison, TS; Hayes, AH; Luderer, JR, 1982) |
"To compare the hemodynamic and humoral effects of increasing doses of captopril, blood pressure, heart rate, plasma renin activity, plasma aldosterone and angiotensin-converting enzyme activity were measured in 10 patients with mild uncomplicated essential hypertension before and after captopril given in an increasing dose of 25, 50 and 100 mg twice a day, with each dose given for 3 days." | 7.66 | Humoral and hemodynamic effects of increasing doses of captopril in patients with essential hypertension. ( Abdel-Haq, B; Magagna, A; Pedrinelli, R; Salvetti, A; Sassano, P, 1982) |
"Ten milligrams nifedipine was administered orally to young and old persons with or without hypertension, and the acute effects of nifedipine on the renin-angiotensin-aldosterone system were studied one half to 3 hours later." | 7.66 | Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension. ( Hiramatsu, K; Kubota, T; Yamada, T; Yamagishi, F, 1982) |
"Infusion of angiotensin II into a patient with dexamethasone-suppressible hyperaldosteronism caused a brisk increase in plasma aldosterone concentration." | 7.66 | 10. Hypertension. A comparison of the effects of angiotensin II infusion and variations in salt intake on plasma aldosterone levels in normal subjects, patients with essential hypertension and patients with hyperaldosteronism. ( Brown, JJ; Fraser, R; Lever, AF; Robertson, JI; Usherwood, T; Zoccali, C, 1983) |
"The effects of endralazine, administered intravenously, on blood pressure, heart rate, forearm blood flow, plasma renin activity, aldosterone, adrenaline and noradrenaline were studied in five patients with essential hypertension." | 7.66 | Effects of intravenous endralazine in essential hypertension. ( Hoffmann, JJ; Thien, T; van T'Laar, A, 1983) |
"Plasma renin activity (PRA), plasma aldosterone (PA), blood uric acid (BUA), plasma concentrations of catecholamines (Pcat) and plasma volume (PV) were measured simultaneously in 24 patients with pregnancy-induced hypertension (PIH)." | 7.66 | Plasma renin activity, blood uric acid and plasma volume in pregnancy-induced hypertension. ( Boulanger, JC; Carayon, A; Coevoet, B; Comoy, E; de Fremont, JF; Demory, JE; Desailly, I; Fievet, P; Pleskov, L; Verhoest, P, 1983) |
"The response of plasma renin activity (PRA), plasma aldosterone, 18-hydroxycorticosterone (18-OH-B), 18-hydroxydeoxycorticosterone (18-OH-DOC) and corticosterone to furosemide were compared in 20 normal control subjects, 16 patients with normal-renin essential hypertension (NREH) and 12 patients with low-renin essential hypertension (LREH)." | 7.66 | Rapid increase of mineralocorticoids after furosemide in low-renin essential hypertension: evidence for 18-hydroxycorticosterone to be a better marker than aldosterone. ( Thayil, G; Weber, PC; Witzgall, H, 1982) |
"1 The long-term effects of the oral angiotensin-converting enzyme inhibitor captopril with the addition of a diuretic (chlorthalidone) were examined in 16 patients with moderate or grave hypertension." | 7.66 | Long-term captopril treatment in moderate to severe hypertension. ( Aguglia, F; Balsano, F; De Mattia, G; Ficara, C; Santucci, A, 1982) |
"The role of the renin-aldosterone axis in mediating responses to antihypertensive treatment was examined in patients with essential hypertension treated with propranolol (n=50) or chlorthalidone (n=50)." | 7.66 | The role of aldosterone in the response to treatment of primary hypertension. ( Drayer, JI; Laragh, JH; Purdy, RE; Weber, MA, 1982) |
"Paradoxical glucose-induced hyperkalemia (GIH) was elicited exclusively in the upright position during captopril treatment in four hypertensive patients (Group 3) without impaired glucose tolerance in three." | 7.66 | Glucose-induced hyperkalemia developing in the upright position in captopril-treated hypertensives. ( Bános, C; Csabuda, M; Gercsák, G; Molnár, Z; Pató, E; Radó, JP, 1982) |
"5 mg and 25 mg) of angiotensin I converting enzyme inhibitor (SQ 14,255, captopril) were administered to 8 patients with essential hypertension on a three-crossover study design, and the time course of mean blood pressure (MBP), plasma renin activity (PRA), plasma angiotensin converting enzyme activity (ACE-A), plasma cortisol (PC) and plasma aldosterone (PA) were determined following administration of the drug." | 7.66 | Effects of various doses of captopril on plasma aldosterone concentrations in patients with essential hypertension. ( Hatano, M; Honda, M; Izumi, Y, 1982) |
"Plasma concentrations and urinary excretion rate of vasopressin (VP) were examined in ten cases of severe hypertension before and during short-term treatment by Captopril (SQ 14225)." | 7.66 | Reduction of plasma and urinary vasopressin during treatment of severe hypertension by captopril. ( Aldiger, JC; Corvol, P; Menard, J; Milliez, P; Soto, ME; Thibonnier, M, 1981) |
"We investigated changes in the renin-angiotensin-aldosterone system in seven patients with essential hypertension during treatment with captopril (SQ 14225) (300 to 450 mg/day) for 12 months." | 7.66 | Captopril in the long-term treatment of essential hypertension: changes in the renin-angiotensin-aldosterone system. ( Hayduk, K; Liebau, G; Riegger, GA; Steilner, H, 1982) |
"Plasma volume (PV), extracellular fluid volume (ECV) serum electrolytes, renin and aldosterone were measured before and after 1 week and 4 months of hydrochlorothiazide (HCT) treatment, 50 mg twice daily, in nine male patients with uncomplicated essential hypertension." | 7.66 | Body fluid volumes and the response of renin and aldosterone to short- and long-term thiazide therapy of essential hypertension. ( Schalekamp, MA; van Brummelen, P, 1980) |
"Twenty-one patients with essential hypertension received a constant infusion of angiotensin II and des-aspartyl1-angiotensin II for 45 min on 2 consecutive days during normal sodium intake." | 7.66 | A comparative study on (des-aspartyl1)-angiotensin II and angiotensin II in patients with essential hypertension. ( Fukuchi, S; Mizuno, K; Yamazaki, M, 1980) |
"Captopril was given for treatment of hypertension alone or in combination with diuretics to 32 patients for 1- to 4-mo periods." | 7.66 | Long-term effects of captopril in hypertension. ( Hata, T; Iwanaga, K; Kumahara, Y; Maruyama, A; Mikami, H; Naka, T; Nakamaru, M; Ogihara, T, 1980) |
"The effect of the converting enzyme inhibitor captopril on arterial pressure, the components of the renin-angiotensin-aldosterone system, and body sodium and potassium content was studied in eight hypertensive patients with renal artery stenosis and, in conjunction with diuretics, in seven patients with hypertension unresponsive to previous treatment." | 7.66 | Captopril in clinical hypertension. Changes in components of renin-angiotensin system and in body composition in relation to fall in blood pressure with a note on measurement of angiotensin II during converting enzyme inhibition. ( Atkinson, AB; Brown, JJ; Davies, DL; Fraser, R; Kelly, P; Leckie, B; Lever, AF; Morton, JJ; Robertson, JI, 1980) |
"Arterial blood pressure and plasma catecholamines, renin activity and aldosterone concentration in 12 patients with severe essential hypertension were studied before and after combined alpha- and beta- adrenoceptor blockade induced by oral labetalol treatment for 2 months." | 7.66 | Plasma catecholamines, renin and aldosterone during combined alpha- and beta- adrenoceptor blockade in patients with severe arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Pedersen, A; Pedersen, EB; Pedersen, G, 1980) |
"A simultaneous analysis of the interrelationships between mean blood pressure (MBP), plasma catecholamines, plasma renin activity (PRA) and aldosterone, exchangeable body sodium, and blood volume was carried out before and after acute and chronic administration of clonidine in 15 patients with essential hypertension, in order to further elucidate the mechanism(s) of action of this drug." | 7.66 | Role of sympathetic nerve inhibition and body sodium-volume state in the antihypertensive action of clonidine in essential hypertension. ( Campese, VM; Massry, SG; Romoff, M; Telfer, N; Weidmann, P, 1980) |
"A case of severe hypertension resistant to multiple drug therapy was controlled with minoxidil, captopril, and propranolol hydrochloride after treatment with these drugs alone or in other combinations had failed." | 7.66 | Interaction of minoxidil and captopril in the treatment of refractory hypertension. ( Matson, JR; Norby, LH; Robillard, JE, 1981) |
"The plasma aldosterone (PA) response to sodium restriction (25 mEq daily for 4 days) and to graded infusions of angiotensin II (AII, 2, 4 and 8 ng/kg/min each for 30 min) during a low-sodium intake were studied in 15 elderly subjects with mild essential hypertension versus 10 elderly normotensive subjects." | 7.66 | Plasma aldosterone response to angiotensin II in sodium-restricted elderly subjects with essential hypertension. ( Kigoshi, T; Miyamoto, M; Morimoto, S; Morise, T; Takeda, R; Takimoto, H; Uchida, K, 1981) |
"The effect of 5 to 9 days of metyrapone administration (400 mg/m2 every 4 h) on aldosterone, deoxycorticosterone, plasma renin activity, electrolyte balance, and blood pressure was investigated in 2 normotensive siblings (one of whom showed limited ACTH reserve), in 3 patients with hypertension and dexamethasone-suppressible hyperaldosteronism, and in a hypertensive patient with primary hyperaldosteronism due to bilateral adrenal hyperplasia." | 7.66 | Mineralocorticoid and metabolic response to metyrapone on normotensive children and children with dexamethasone-suppressible and primary hyperaldosteronism. ( Levine, LS; New, MI; Sonino, N, 1981) |
"Plasma aldosterone (PA) responses to sodium restriction (25 mEq sodium/day for 4 days) and to graded angiotensin II (AII) infusions (2, 4 and 8 ng/kg/min each for 30 min) during a low sodium intake were studied in 14 subjects with low renin essential hypertension (LREH) versus 16 normotensive subjects." | 7.66 | Aldosterone responsiveness to angiotensin II after sodium restriction in subjects with low renin essential hypertension. ( Fujimura, A; Hashiba, T; Honjo, A; Kigoshi, T; Morimoto, S; Takeda, R; Uchida, K, 1982) |
"For distinguishing primary aldosteronism from essential hypertension, we use simple direct radioimmunoassays for "aldosterone" (aldosterone and other materials that react with the antibody to aldosterone) and "18-hydroxycorticosterone" (similarly) in unprocessed urine." | 7.66 | Direct radioimmunoassays for "aldosterone" and "18-hydroxycorticosterone" in unprocessed urine, and their use in screening to distinguish primary aldosteronism from hypertension. ( Abdelhamid, S; Benraad, TJ; Haack, D; Hofman, J; Lichtwald, K; Vecsei, P, 1982) |
"The most abundant substance in the urinary free steroid fraction of patients with primary aldosteronism has been identified as 18-hydroxycortisol." | 7.66 | Hypersecretion of a new corticosteroid, 18-hydroxycortisol in two types of adrenocortical hypertension. ( Chu, MD; Ulick, S, 1982) |
"In view of recent evidence that spironolactone may inhibit synthesis of corticosteroids by a direct effect on the adrenal cortex, adrenocortical function was studied in eight patients with essential hypertension who had been treated with spironolactone from 3 months to 14 years." | 7.66 | Long term spironolactone and the adrenal cortex in essential hypertension. ( Gorchein, A; Horth, CE; James, VH; Lewis, PS; May, CN, 1980) |
"Plasma concentrations of angiotensin II (AII), aldosterone, 18-hydroxycorticosterone and cortisol were measured in seven patients with benign essential hypertension and in seven age-matched control subjects before, and at frequent intervals for 2 h after the intravenous injection of frusemide (40 mg)." | 7.66 | Increased 18-hydroxycorticosterone responses to frusemide in essential hypertension. ( Fraser, R; Mason, PA; Semple, PF, 1980) |
"Sequential changes in plasma renin activity and urinary aldosterone and noradrenaline were assessed in eight patients with severe hypertension after minoxidil had been added to their treatment." | 7.66 | Need for beta-blockade in hypertension reduced with long-term minoxidil. ( Brunner, HR; Ferguson, RK; Gavras, H; Jaeger, P; Jequier, E; Turini, G, 1978) |
"To determine the mechanism underlying altered adrenal responsiveness in patients with essential hypertension, the renin-angiotensin-aldosterone axis was assessed in normotensive and hypertensive subjects using three pharmacological probes: SQ 20881, a converting enzyme inhibitor; saralasin, a competitive angiotensin antagonist with prominent agonist properties; and angiotensin itself." | 7.66 | The adrenal receptor for angiotensin II is altered in essential hypertension. ( Dluhy, RG; Hollenberg, NK; Moore, TJ; Swartz, SL; Williams, GH, 1979) |
") before and during treatment with spironolactone (Sp, 75--100 mg/day) for at least 8 months was studied in 11 patients with essential hypertension." | 7.66 | Reduced response of plasma aldosterone to acute ACTH stimulation during long-term treatment with spironolactone in essential hypertension. ( Kim, KS; Miyamori, I; Miyamoto, M; Morimoto, S; Takeda, R; Uchida, K, 1979) |
"We substituted minoxidil for dihydralazine in the treatment of 10 patients with refractory hypertension." | 7.66 | [Effects of minoxidil on blood pressure and plasma volume in refractory hypertension (author's transl)]. ( Alhenc-Gelas, F; Ménard, J; Morgado Vital, A; Plouin, PF, 1979) |
"The plasma aldosterone response to infused angiotensin II was determined in normal controls and in patients with normal renin and with low renin essential hypertension." | 7.66 | Enhanced adrenal responsiveness to angiotensin II in patients with low renin essential hypertension. ( Adlin, VE; Channick, BJ; Kanefsky, TM; Marks, AD; Marks, DB, 1979) |
"To determine if the abnormally large increases in levels of plasma aldosterone which occur during infusion of angiotensin II in some patients with essential hypertension are due to abnormal decreases in the metabolic clearance of aldosterone, we measured clearances of aldosterone before and during infusion of angiotensin II in 12 patients with essential hypertension and in 10 normal subjects." | 7.66 | The metabolic clearance of aldosterone decreases similarly during infusion of angiotensin II in patients with essential hypertension and in normal subjects. ( Brown, RD; Wisgerhof, M, 1979) |
"In essential hypertension mean basal (supine) and stimulated plasma renin activity (2 h upright posture + 40 mg furosemide intraveneously) decreased progressively with age." | 7.66 | Age- and sex-related differences in plasma aldosterone in essential hypertension. Relationship to plasma renin activity. ( Alasso, I; Glänzer, K; Vetter, H; Vetter, W, 1979) |
"Plasma concentrations of angiotensin II (AII) were studied in 36 patients with primary (essential) hypertension and 15 normotensive control subjects during basal (1 h supine rest), upright and frusemide-stimulated (80 mg orally) conditions." | 7.66 | Angiotensin II in primary hypertension, relationship to plasma renin activity, aldosterone and urinary electrolytes. ( Karlberg, BE; Tolagen, K, 1979) |
"Adrenal responsiveness to angiotensin II (AII) and the diastolic blood pressure responses to saralasin were studied in 19 patients with high renin essential hypertension (HREH) on a 10-meq Na(+)/100 meq K(+) diet." | 7.66 | Abnormal adrenal responsiveness and angiotensin II dependency in high renin essential hypertension. ( Bavli, SZ; Dluhy, RG; Hollenberg, NK; Leung, FK; Moore, TJ; Solomon, HS; Williams, GH, 1979) |
"3%) the normal, aldosterone-18-glucuronide concentration was clinically misleading, but increased free aldosterone and/or tetrahydroaldosterone values suggested the presence of hyperaldosteronism, which in many of these cases was confirmed by elevated excretion of the possible major aldosterone precursor 18-hydroxycorticosterone (18-OH-B)." | 7.66 | Dissociation in the excretion of different aldosterone metabolites and unmetabolized ('free') aldosterone in hypertension. ( Abdelhamid, S; Fiegel, P; Gless, KH; Haack, D; Lichtwald, K; Vecsei, P; Walb, D, 1979) |
"Arterial blood pressure and plasma catecholamines, renin activity and aldosterone concentration in 12 patients with severe essential hypertension were studied before and after combined alpha- and beta-adrenergic receptor blockage induced by oral labetalol treatment for 2 months." | 7.66 | Effect of oral labetalol on plasma catecholamines, renin and aldosterone in patients with severe arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Pedersen, A; Pedersen, EB; Pedersen, G, 1979) |
"The effect of furosemide on urinary kallikrein excretion was studied in 10 patients with essential hypertension and 9 normal volunteer subjects." | 7.66 | Effect of furosemide on urinary kallikrein excretion in patients with essential hypertension. ( Abe, K; Chiba, S; Irokawa, N; Ito, T; Kusaka, T; Miyazaki, S; Ritz, K; Saito, K; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K, 1978) |
"Studies were undertaken to determine if the dissociation of aldosterone and plasma renin activity in low-renin essential hypertension is due to altered adrenal responsiveness to angiotensin II." | 7.66 | Increased adrenal sensitivity to angiotensin II in low-renin essential hypertension. ( Brown, RD; Wisgerhof, M, 1978) |
"To determine the influence of dietary sodium intake on the effects of hydrochlorothiazide (HCT) on blood pressure (BP), serum electrolytes, renin and aldosterone, nine male patients with uncomplicated essential hypertension were studied during the following therapeutic regimes: 1) sodium restriction alone (50 mmol/day), 2) sodium restriction combined with HCT (50 MG TWICE DAILY), 3) HCT alone, and 4) sodium restriction combined with HCT." | 7.66 | Influence of sodium intake on hydrochlorothiazide-induced changes in blood pressure, serum electrolytes, renin and aldosterone in essential hypertension. ( de Graeff, J; Schalekamp, M; van Brummelen, P, 1978) |
"In order to evaluate the relationship between aldosterone status and the blood pressure-lowering effect of spironolactone, 38 patients with essential hypertension were treated with spironolactone (400 mg/day) during one week in hospital on a rigidly sodium-restricted diet." | 7.66 | Role of aldosterone in the antihypertensive effect of spironolactone in essential hypertension. ( Benraad, H; Benraad, T; Drayer, J; Hoefnagels, W; Kloppenborg, P, 1978) |
"In 34 patients saralasin was infused after variable degrees of sodium depletion in order to differentiate between essential and renin-induced hypertension." | 7.66 | [Saralasin-induced changes of blood pressure, renin and aldosterone in essential and renal hypertension (author's transl)]. ( Beyer, J; Hayduk, K; Liebau, G; Steiner, B, 1978) |
"The blood pressure response to the angiotensin II analog 1-sar-8-ala-angiotensin II, or saralasin, was studied in five patients with clinical and laboratory evidence of Cushing's syndrome." | 7.66 | Evidence for an angiotensinogenic mechanism of the hypertension of Cushing's syndrome. ( Anderson, GH; Dalakos, TG; Elias, AN; Schroeder, ET; Streeten, DH, 1978) |
"The effect of indomethacin on plasma renin activity (PRA), urinary aldosterone, 17 OH ketogenic steroids and plasma cortisol was studied in twenty-three patients with essential hypertension and compared in eleven patients to oxprenolol effect by 2 x 2 factorial trial." | 7.66 | The effect of indomethacin on plasma renin activity and urinary aldosterone of patients with essential hypertension. ( Arzilli, F; Cavasinni, L; Pedrinelli, R; Poli, L; Salvetti, A; Sassano, P, 1978) |
"Adrenal and vascular responsiveness to graded doses of angiotensin II (A II) were recorded for seven normal subjects and 12 patients with essential hypertension while in balance on an intake of 200 mEq sodium/100 mEq potassium." | 7.65 | Enhanced aldosterone response to angiotensin II in human hypertension. ( Dluhy, RG; Kisch, ES; Williams, GH, 1976) |
"The blood pressure response to propranolol treatment was analyzed retrospectively in 187 patients with benign essential hypertension." | 7.65 | Unexpected pressor responses to propranolol in essential hypertension. An interaction between renin, aldosterone and sympathetic activity. ( Case, DB; Drayer, JI; Keim, HJ; Laragh, JH; Weber, MA, 1976) |
"To understand the role of the renin-angiotensin-aldosterone system in the pathogenesis of human hypertension, in serial studies we have blocked the system using three different pharmacologic probes: 1) reduction of renin secretion by administration of the beta receptor blocker, propranolol; 2) blockade of the action of angiotensin II by infusion of saralasin, a competitive antagonist of angiotensin II; and 3) blockade of the enzymatic conversion of angiotensin I to angiotensin II by infusing a nonapeptide competitive inhibitor." | 7.65 | Blockade of renin or angiotensin for understanding human hypertension: a comparison of propranolol, saralasin and converting enzyme blockade. ( Case, DB; Keim, H; Laragh, JH; Wallace, JM, 1977) |
"To investigate the interaction between the renin angiotensin aldosterone system and the renal prostaglandin (PG), urinary excretion of PGE, urinary excretion of main urinary metabolite (MUM) of PGF2a, urinary excretion of aldosterone, and plasma renin activity were measured before and after infusion of 1-Sar-8-Ile-Angiotensin II, a specific competitive inhibitor of angiotensin II, in 18 patients with essential hypertension under normal and low sodium diets." | 7.65 | Effects of 1-Sar-8-Ile-angiotensin II on urinary prostaglandin excretion in patients with essential hypertension. ( Abe, K; Chiba, S; Irokawa, N; Ito, T; Otsuka, Y; Ritsu, K; Saito, K; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K, 1977) |
"Adrenal responsiveness to angiotensin II was evaluated in patients with "normal-renin" hypertension." | 7.65 | Aldosterone regulation in essential hypertension: altered adrenal responsiveness to angiotensin II. ( Dluhy, RG; Moore, TJ; Williams, GH, 1977) |
"In 50 patients with essential hypertension treated with chlorthalidone, 100 mg daily for 6 weeks, treatment responders (fall in mean pressure, greater than or equal to 10%) and nonresponders experienced similar weight and electrolyte changes." | 7.65 | Disparate patterns of aldosterone response during diuretic treatment of hypertension. ( Drayer, JI; Laragh, JH; Rev, A; Weber, MA, 1977) |
"To investigate the role of the renin angiotensin system in the pathogenesis of hypertension in Cushing's syndrome two patients with hypercorticism were infused with 20 mg saralasin (1-sar-8-ala-angiotensin II) over a period of 30 minutes under constant blood pressue control." | 7.65 | The effect of saralasin (1sar-8-ala-angiotensin II) on blood pressure in patients with Cushing's syndrome. ( Beckerhoff, R; Cottier, P; Redlich, B; Siegenthaler, W; Vetter, H; Vetter, W, 1976) |
"Plasma aldosterone concentration (PAC), plasma renin concentration (PRC), plasma potassium, plasma sodium and blood pressure (BP) have been measured in 22 patients with essential hypertension before and after treatment for one month with alprenolol." | 7.65 | Relationship between plasma aldosterone concentration and plasma potassium in patients with essential hypertension during alprenolol treatment. ( Kornerup, HJ; Pedersen, EB, 1976) |
"Compared with a group of normal pregnant women, matched for age, parity, posture, and length of gestation, women with hypertension and proteinuria in the last trimester had significantly lower plasma concentrations of renin, renin substrate and angiotensin II." | 7.65 | Studies of the renin-angiotension-aldosterone system, cortisol, DOC, and ADH in normal and hypertensive pregnancy. ( Doig, A; Fraser, R; Morton, JJ; Parboosingh, J; Robertson, JI; Weir, RJ; Wilson, A, 1976) |
"The responses of blood pressure, plasma renin activity (PRA) and plasma aldosterone concentration (PAC) to infusion of either angiotensin II (10 ng/Kg/min) or norepinephrine (100 ng/Kg/min) were observed in 25 patients with essential hypertension." | 7.65 | Effect of pressor agents on blood pressure, plasma renin activity and plasma aldosterone concentration in essential hypertension. ( Yamamoto, Y, 1975) |
"Plasma aldosterone, plasma renin activity, sodium and potassium in the plasma and the urine were determinated under acute stimulation with saline-depletion (furosemide) and under acute suppression with saline infusion in 40 patients with primary hypertension stage I, 19 patients with primary hypertension stages II and III, and 11 patients with renal hypertension (chronic glomerulonephritis and chronic pyelonephritis)." | 7.65 | [Plasma aldosterone and plasma renin activity in patients with essential and renal hypertension under acute stimulation with saline depletion and acute suppression with saline infusion]. ( Klaus, D; Klumpp, F; Lemke, R; Zehner, J; Zöfel, P, 1975) |
"The anti-hypertensive effect of spironolactone and thiabutazide was tested on 47 unselected patients with primary hypertension." | 7.65 | [Spironolactone and thiabutazide in the treatment of essential hypertension (author's transl)]. ( Braun, B; Klaus, D; Klump, F; Lemke, R; Zehner, J; Zöfel, P, 1975) |
"The response of plasma aldosterone to fludrocortisone administration (400 mug 12-hourly for 3 days) was studied in twenty-two patients with primary hyperaldosteronism." | 7.65 | Response of plasma aldosterone to fludrocortisone in primary hyperaldosteronism and other forms of hypertension. ( Allison, ME; Brown, JJ; Ferriss, JB; Fraser, R; Lever, AF; Luke, RG; Padfield, PL; Robertson, JI, 1975) |
"Acebutolol, a new cardioselective beta-blocking agent, has been given for 5 days, at a daily dosage of 600 mg to 8 patients with mild essential hypertension." | 7.65 | [Effects of acebutolol on the renin-aldosterone system in essential arterial hypertension]. ( Corvol, P; Ménard, J; Plouin, PF, 1975) |
" have applied the diazoxide test for the screening of primary hiperaldosteronism to 22 nephropatic patients suffering from hypertension and with different degrees of renal function." | 7.65 | [Diazoxide test in the diagnosis of arterial hypertension: modifications in the levels of renin and aldosterone in blood of patients with various restrains of the renal function]. ( Albertini, A; Cecchettin, M; Ghielmi, S; Maiorca, R; Orlandini, A; Signorini, C, 1975) |
"Plasma renin activity, arterial and venous angiotensin II (A II), plasma aldosterone, and sodium excretion were measured in a group of 101 patients with mild essential hypertension." | 7.65 | Relation between plasma renin activity, angiotensin, and aldosterone and blood pressure in mild untreated hypertension. ( Horvath, JS; Moore, MA; Russell, RP; Walker, WG; Whelton, P, 1976) |
"The effect of triamterene, a potassium-retaining natriuretic and diuretic agent, on arterial blood pressure was studied in 31 patients with essential hypertension; there were seven patients with low plasma renin activity and 24 patients with normal plasma renin activity." | 7.65 | Triamterene-induced changes in aldosterone and renin values in essential hypertension. Evidence of a role for aldosterone in preventing blood pressure reduction. ( Drayer, JI; Keim, HJ; Laragh, JH; Thurston, H, 1976) |
"A 44-year old woman without history of hypertension in her 4 pregnancies was hospitalized for hemoptysia and found to have hypertension 230/120 to 250/150: she had been taking 2 tablets of Lyndiol (5 mg lynestrenol and ." | 7.65 | [A case of arterial hypertension imputable to an estroprogestational contraceptive. Implication of the renin-angiotensin-aldosterone system]. ( Béquart, P; Boulangé, M; Camelot, G; Fontenaille, C, 1969) |
"The effect of prolonged preoperative treatment with spironolactone has been studied in a series of 67 patients with hypertension, aldosterone excess, and low plasma renin." | 7.65 | Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin. ( Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Haywood, E; Lever, AF; Robertson, JI, 1972) |
"The content of aldosterone, corticosterone, and cortisol has been assayed in normal adrenal tissue obtained at autopsy and in adrenal adenomas from both normotensive and hypertensive patients obtained at autopsy and from patients with primary aldosteronism obtained at surgery." | 7.64 | The steroid content of adrenal adenomas and measurements of aldosterone production in patients with essential hypertension and primary aldosteronism. ( Kaplan, NM, 1967) |
"Aldosterone was not associated with IMMR, insulin sensitivity, or blood pressure and was unaffected by weight loss." | 6.87 | Aldosterone Is Not Associated With Metabolic and Microvascular Insulin Sensitivity in Abdominally Obese Men. ( de Leeuw, PW; Houben, AJHM; Joris, PJ; Kusters, YHAM; Mensink, RP; Plat, J; Schalkwijk, CG; Scheijen, JLJM; Schütten, MTJ; Stehouwer, CDA; van de Waarenburg, MPH, 2018) |
"Aldosterone excretion was determined by 24 h urine (24h-UAldo) collected at randomization and after 6 months of follow-up." | 6.84 | Effects of continuous positive airway pressure treatment on aldosterone excretion in patients with obstructive sleep apnoea and resistant hypertension: a randomized controlled trial. ( Cavalcanti, AH; Cortez, AF; de Souza, F; Margallo, V; Muxfeldt, ES; Salles, GF, 2017) |
"Primary aldosteronism (PA) is an endocrine related condition leading to arterial hypertension due to inappropriately high and unregulated aldosterone concentration." | 6.82 | Primary Aldosteronism, Aldosterone, and Extracellular Vesicles. ( Carvajal, CA; Fardella, CE; Pérez, JA; Tapia-Castillo, A, 2022) |
"Primary aldosteronism (PA) affects millions of individuals worldwide." | 6.82 | High Prevalence of Autonomous Aldosterone Production in Hypertension: How to Identify and Treat It. ( Lieberman, L; Turcu, AF; Wannachalee, T, 2022) |
"Primary aldosteronism (PA) is the most common and potentially curable form of secondary hypertension, affecting 5-10% of primary care patients with hypertension." | 6.82 | Performance of the aldosterone-to-renin ratio as a screening test for primary aldosteronism in primary care. ( Ariens, J; Choy, KW; Horvath, AR; Yang, J, 2022) |
"Primary aldosteronism (PA) is the leading cause of secondary hypertension, accounting for over 10% of patients with high blood pressure." | 6.82 | Update on the Genetics of Primary Aldosteronism and Aldosterone-Producing Adenomas. ( Faucz, FR; Hannah-Shmouni, F; Pitsava, G; Stratakis, CA, 2022) |
"Increased abdominal obesity is associated with increased cardiovascular risk, especially in African American women." | 6.82 | Relationship Between Obesity, Hypertension, and Aldosterone Production in Postmenopausal African American Women: A Pilot Study. ( Bakris, GL; Laffin, LJ; Liao, C; Majewski, C, 2016) |
"The high prevalence of obstructive sleep apnea in patients with resistant hypertension could be mediated by an activation of the renin-angiotensin-aldosterone system." | 6.79 | A randomized controlled study of CPAP effect on plasma aldosterone concentration in patients with resistant hypertension and obstructive sleep apnea. ( Espinel, E; Ferrer, R; Lloberes, P; Martínez-Garcia, MA; Ramon, MA; Romero, O; Sampol, G; Segarra, A; Tovar, JL, 2014) |
"Aldosterone breakthrough was observed in 22 of the subjects (55%)." | 6.78 | Effect of aldosterone breakthrough on albuminuria during treatment with a direct renin inhibitor and combined effect with a mineralocorticoid receptor antagonist. ( Fukuda, S; Sato, A, 2013) |
"Aldosterone production causes vascular injury and may occur despite the long-term administration of angiotensin converting enzyme-inhibitors (ACE-I) (ie, aldosterone breakthrough)." | 6.74 | Effects of ARB or ACE-inhibitor administration on plasma levels of aldosterone and adiponectin in hypertension. ( Hoshino, J; Hosoi, T; Iwasaki, T; Kawachi, K; Kurabayashi, M; Morishita, K; Nakamura, T; Ohyama, Y; Saito, T; Saito, Y, 2009) |
"Amiloride 40 mg was as effective as the other diuretics." | 6.73 | The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio. ( Ashby, MJ; Brown, MJ; Hood, SJ; Taylor, KP, 2007) |
"Aldosterone is a mineralocorticoid hormone that controls body fluid and electrolyte balance." | 6.72 | Aldosterone, Inflammation, Immune System, and Hypertension. ( Ferreira, NS; Paradis, P; Schiffrin, EL; Tostes, RC, 2021) |
"Primary aldosteronism (PA) is one of the most frequent curable forms of secondary hypertension." | 6.72 | Functional Characteristic and Significance of Aldosterone-Producing Cell Clusters in Primary Aldosteronism and Age-Related Hypertension. ( Azizan, EA; Pauzi, FA, 2021) |
"The ARR threshold to screen for primary aldosteronism may be based on measurement of irR." | 6.71 | Active renin versus plasma renin activity to define aldosterone-to-renin ratio for primary aldosteronism. ( Ferrari, P; Nicod, J; Nussberger, J; Saner, E; Shaw, SG, 2004) |
"Aldosterone antagonism has BP-independent effects on arterial stiffness." | 6.71 | Aldosterone-to-renin ratio, arterial stiffness, and the response to aldosterone antagonism in essential hypertension. ( Feely, J; Mahmud, A, 2005) |
"Primary aldosteronism is a specifically treatable and potentially curable form of secondary hypertension." | 6.70 | Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism. ( Chiandussi, L; Milan, A; Morello, F; Mulatero, P; Paglieri, C; Rabbia, F; Veglio, F, 2002) |
"When amiloride was withdrawn for 2 weeks, there was a large increase in blood pressure of 17/8+/-4/2 mm Hg (systolic, P<0." | 6.70 | Amiloride, a specific drug for hypertension in black people with T594M variant? ( Baker, EH; Dong, Y; Duggal, A; Ireson, NJ; MacGregor, GA; Markandu, ND; Wood, M, 2002) |
"Losartan appears to be an effective anti-hypertensive agent in patients with mild to moderate hypertension." | 6.68 | Effects of losartan on the renin-angiotensin-aldosterone axis in essential hypertension. ( Bauer, IH; Lau-Sieckman, A; Reams, GP; Wu, Z, 1995) |
" All patients received three dosing regimens administered in random order: (a) intravenous frusemide: 40 mg bolus then 40 mg h-1 for 3 h, (b) captopril: two 12." | 6.68 | The renin angiotensin aldosterone system and frusemide response in congestive heart failure. ( Cerimele, B; Greene, P; Reed, S; Ryan, T; Schwertschlag, U; Voelker, J; Weinberger, M, 1995) |
"Neuropeptide Y (NPY) has been recently characterized as a circulating vasoconstrictor peptide which is co-stored with noradrenaline in sympathetic neurons." | 6.68 | [Concentration of neuropeptide Y in serum of patients with primary hypertension]. ( Halawa, B; Salomon, P, 1996) |
"Essential hypertension is a very common disease in the world." | 6.68 | [Selected components of the kallikrein-kinin system and of the renin-angiotensin-aldosterone system in offspring of parents with hypertension]. ( Marzecka, J, 1996) |
"Losartan (DuP 753) is a novel orally active angiotensin II antagonist that lowers blood pressure." | 6.67 | Hemodynamic and humoral effects of the angiotensin II antagonist losartan in essential hypertension. ( Carroll, J; Grossman, E; Peleg, E; Rosenthal, T; Shamiss, A, 1994) |
"Treatment with felodipine ER over 2 weeks increased sympathetic outflow as indicated by elevated plasma norepinephrine levels, whereas plasma epinephrine was mainly unaffected, as were plasma renin and aldosterone levels." | 6.67 | Catecholamines and the renin-angiotensin-aldosterone system during treatment with felodipine ER or hydrochlorothiazide in essential hypertension. ( Binner, L; Gabrielsen, F; Hombach, V; Koenig, W; Rosenthal, J; Sund, M, 1991) |
"Aldosterone levels were also increased after three months, but without a subsequent decrease." | 6.67 | Isradipine in the treatment of hypertension. Some additional effects observed during a one-year study. ( Mayer, O; Polivkova, H; Rottenborn, J, 1991) |
"Nicardipine (80 mg/day) was given orally for 12 weeks and no dietary restrictions were imposed." | 6.67 | Efficacy of nicardipine slow release (SR) on hypertension, potassium balance and plasma aldosterone in idiopathic aldosteronism. ( Bisbocci, D; Chiandussi, L; Pinna, G; Piras, D; Rabbia, F; Veglio, F, 1990) |
"Primary hyperaldosteronism (PA) is a well-known cause of hypertension although its exact prevalence amongst patients with apparent essential hypertension has been a matter of debate." | 6.66 | Five Reasons for the Failure to Diagnose Aldosterone Excess in Hypertension. ( Chrousos, GP; Kaltsas, G; Markou, A; Piaditis, GP, 2020) |
"Bopindolol is a new long-acting, nonselective beta-adrenoceptor antagonist with partial agonist activity." | 6.66 | The clinical pharmacology of bopindolol, a new long-acting beta-adrenoceptor antagonist, in hypertension. ( Boomsma, F; Derkx, FH; Man in 't Veld, AJ; Mulder, P; Schalekamp, MA; van den Meiracker, AH; van Eck, HJ, 1987) |
"Celiprolol is a newly developed cardioselective beta-blocking agent with mild beta 2-agonist and weak alpha 2-antagonist properties." | 6.66 | Effects of celiprolol on plasma renin, aldosterone, norepinephrine and epinephrine in primary hypertension. ( DeQuattro, V; Hernandez, PH; Kimura, S; Lee, DD, 1988) |
" Further measurements were made during a series of intensive study days, and the most important additional finding was a pharmacokinetic interaction that resulted in increased peak concentrations and bioavailability of prazosin." | 6.66 | The combination of prazosin and verapamil in the treatment of essential hypertension. ( Campbell, L; Elliott, HL; Meredith, PA; Reid, JL, 1988) |
"Nicardipine appears to blunt the secretion of aldosterone responding to an increased PRA possibly through its calcium-antagonizing action." | 6.66 | Multiple oral doses of nicardipine, a calcium-entry blocker: effects on renal function, plasma renin activity, and aldosterone concentration in mild-to-moderate essential hypertension. ( Aoyagi, K; Baba, T; Ishizaki, T; Murabayashi, S; Takebe, K; Tamasawa, N, 1987) |
"Guanfacine monotherapy was again shown to be an effective initial treatment for mild essential hypertension with no adverse influence on serum lipids." | 6.66 | Guanfacine as monotherapy for systemic hypertension. ( Blackshear, JL; Fillingim, JM; Strauss, A; Strauss, M, 1986) |
"Captopril was administered orally in 2 daily doses of 25 to 200 mg." | 6.65 | Uncontrollable hypertension in patients on hemodialysis: long-term treatment with captopril and salt subtraction. ( Brunner, HR; Gavras, H; Guignard, JP; Turini, GA; Waeber, B; Wauters, JP, 1981) |
"In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)." | 6.65 | [Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984) |
"Labetalol was more effective in lowering blood pressure but less effective in reducing pulse rate of plasma angiotensin II concentration." | 6.64 | Effect of blood pressure angiotensin II and aldosterone concentrations during treatment of severe hypertension with intravenous labetalol: comparison with propranolol. ( Brown, JJ; Fraser, R; Lever, AF; Morton, JJ; Robertson, JI; Rosei, EA; Trust, PM, 1976) |
"Treatment with propranolol resulted in marked suppression of the plasma renin activity (1." | 6.64 | Intrapatient comparison of treatment with chlorthalidone, spironolactone and propranolol in normoreninemic essential hypertension. ( Benraad, TJ; Drayer, JI; Festen, J; Kloppenborg, PW; van't Laar, A, 1975) |
"Primary aldosteronism (PA) is the most prevalent cause of secondary hypertension (3%-32% of hypertensive patients)." | 6.61 | The aldosterone to renin ratio in the diagnosis of primary aldosteronism: Promises and challenges. ( Denieffe, S; Fitzgibbon, MC; Griffin, TP; O'Shea, PM, 2019) |
"Primary aldosteronism is the most common form of secondary hypertension." | 6.58 | Overview of aldosterone-related genetic syndromes and recent advances. ( Boulkroun, S; Fernandes-Rosa, FL; Zennaro, MC, 2018) |
"Obese subjects often exhibit hyperaldosteronism, with increased salt sensitivity of blood pressure (BP)." | 6.53 | The Role of Aldosterone in Obesity-Related Hypertension. ( Fujita, T; Kawarazaki, W, 2016) |
"Obesity is a serious health hazard with rapidly increasing prevalence in the United States." | 6.53 | Obesity, hypertension and aldosterone: is leptin the link? ( Bollag, WB; Xie, D, 2016) |
"Obesity is a multifactorial disease associated with hypertension." | 6.52 | Reviving the use of aldosterone inhibitors in treating hypertension in obesity. ( Belin De Chantemèle, EJ; Huby, AC, 2015) |
"Obesity is epidemic and is associated with increased blood pressure, which often manifests as treatment-resistant hypertension." | 6.50 | A critical review of the evidence supporting aldosterone in the etiology and its blockade in the treatment of obesity-associated hypertension. ( Brook, RD; Byrd, JB, 2014) |
"Other than treatment for weight loss, treatment of hypertension with specific antihypertensive medications that block or reduce aldosterone action are appropriate in obese patients." | 6.50 | Increased aldosterone: mechanism of hypertension in obesity. ( Flynn, C, 2014) |
"Resistant hypertension is a clinically distinct subgroup of hypertension defined by the failure to achieve blood pressure control on optimal dosing of at least 3 antihypertensive medications of different classes, including a diuretic." | 6.50 | Pathophysiology and treatment of resistant hypertension: the role of aldosterone and amiloride-sensitive sodium channels. ( Calhoun, DA; Judd, EK; Warnock, DG, 2014) |
"Hypertension is traditionally considered a disease in which elevated blood pressure contributes to inflammation and activation of the immune system, leading to cardiovascular injury and end-organ damage." | 6.49 | Immune system alterations by aldosterone during hypertension: from clinical observations to genomic and non-genomic mechanisms leading to vascular damage. ( Barake, MF; Campino, C; Fardella, CE; Kalergis, AM; Letelier, NA; Muñoz-Durango, N, 2013) |
"Hypertension is an established risk factor for stroke, premature coronary artery disease and heart failure." | 6.49 | Aldosterone synthase inhibition in hypertension. ( Andersen, K, 2013) |
"A close association exists between hyperaldosteronism, RHTN, and obstructive sleep apnea (OSA) based upon recent studies which indicate that OSA is worsened by aldosterone-mediated fluid retention." | 6.48 | Resistant hypertension and aldosterone: an update. ( Ahmed, MI; Calhoun, DA; Clark, D, 2012) |
" The observation of reduced nitric oxide bioavailability in hyperaldosteronism implied the generation of oxidative stress by aldosterone." | 6.48 | Aldosterone, oxidative stress, and NF-κB activation in hypertension-related cardiovascular and renal diseases. ( Queisser, N; Schupp, N, 2012) |
"In the setting of primary aldosteronism, elevated aldosterone levels are associated with increased blood pressure." | 6.46 | Aldosterone and arterial hypertension. ( Obermayer-Pietsch, B; Pieber, TR; Pilz, S; Ritz, E; Tomaschitz, A, 2010) |
"Aldosterone was in the past considered only as a prohypertensinogenic agent." | 6.46 | Aldosterone in uremia - beyond blood pressure. ( Koleganova, N; Ritz, E, 2010) |
"Eplerenone has been reported to have anti-hypertensive and protective effects on cardiovascular and renal injury in salt-sensitive hypertensive animal models, such as the Dahl salt-sensitive (DS) hypertensive rat and leptin receptor-deficient spontaneously hypertensive rat (SHR/cp)." | 6.45 | Effects of eplerenone, a selective mineralocorticoid receptor antagonist, on clinical and experimental salt-sensitive hypertension. ( Takeda, Y, 2009) |
"Features of visceral obesity and obstructive sleep apnea that may stimulate aldosterone secretion are described here." | 6.44 | Obesity, sleep apnea, aldosterone, and hypertension. ( Goodfriend, TL, 2008) |
"Aldosterone has also been shown to exert a number of effects in the central nervous system." | 6.44 | Aldosterone and the vasculature: mechanisms mediating resistant hypertension. ( Duprez, DA, 2007) |
"Aldosterone is an important mediator in the pathogenesis of heart failure, and increased plasma aldosterone levels are associated with a poor prognosis." | 6.44 | Drug insight: aldosterone-receptor antagonists in heart failure--the journey continues. ( Francis, GS; Kalidindi, SR; Tang, WH, 2007) |
"Overweight and obesity are associated with arterial hypertension." | 6.44 | The association of aldosterone with obesity-related hypertension and the metabolic syndrome. ( Bochud, M; Burnier, M; Vogt, B, 2007) |
"The syndrome of primary aldosteronism, however, encompasses a wide spectrum of disorders that will require better definition." | 6.44 | Aldosterone and refractory hypertension. ( Nyirenda, MJ; Padfield, PL, 2007) |
"Metabolic syndrome is an aggregation of hypertension, diabetes and dyslipidaemia." | 6.44 | Aldosterone in salt-sensitive hypertension and metabolic syndrome. ( Fujita, T, 2008) |
"Aldosterone plays an important role in the pathogenesis of cardiovascular disease." | 6.43 | Role of cardiovascular aldosterone in hypertension. ( Takeda, Y, 2005) |
"Aldosterone is an important and independent target for therapeutic intervention in hypertension and hypertension-related diseases." | 6.42 | Aldosterone receptor antagonists for hypertension: what do they offer? ( Krum, H; Liew, D, 2003) |
"The classical form of primary aldosteronism is a rare disease with prevalence rates of 0." | 6.42 | [The aldosterone to Renin ratio in secondary hypertension]. ( Reincke, M; Seiler, L, 2003) |
"Aldosterone has been only considered as a humoral factor playing a role in salt and water homeostasis and as a consequence controlling arterial blood pressure." | 6.41 | [Aldosterone and cardiovascular diseases, more than water and salt retention]. ( Duprez, D, 2002) |
"Aldosterone has been identified as a critically important neurohormone with direct detrimental effects on the myocardium." | 6.41 | Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure. ( Miller, AB; Srivastava, P, 2001) |
"Among these, classic primary hyperaldosteronism and its glucocorticoid remediable variety, in which hypertension is secondary to aldosterone production, must be considered." | 6.40 | [Hypertension and mineralocorticoids. Usefulness of renin and aldosterone measurements]. ( Fardella, CE; Montero, J; Mosso, L, 1999) |
"According to the primary aldosteronism surgical outcome (PASO) criteria, complete and partial clinical success was achieved in 21 (40." | 5.91 | Catheter-based adrenal ablation: an alternative therapy for patients with aldosterone-producing adenoma. ( He, H; Jiang, J; Li, Q; Li, Y; Liu, X; Sun, F; Yan, Z; Zhang, H; Zhao, Z; Zhou, X; Zhu, Z, 2023) |
"Primary aldosteronism (PA) screening relies on an elevated aldosterone to renin ratio with a minimum aldosterone level, which varies from 10 to 15 ng/dL (277-415." | 5.91 | Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening. ( Almeida, MQ; Bortolotto, LA; Brito, LP; Carnevale, FC; Cavalcante, ACBS; Chambo, JL; Coelho, FMA; Consolim-Colombo, FM; Drager, LF; Fagundes, GFC; Fragoso, MCBV; Freitas, TC; Goldbaum, TS; Latronico, AC; Ledesma, FL; Maciel, AAW; Mendonca, BB; Pereira, MAA; Petenuci, J; Pilan, B; Pio-Abreu, A; Silveira, JV; Srougi, V; Tanno, FY; Vilela, LAP; Zerbini, MCN, 2023) |
"After genetic analysis, a diagnosis of Liddle syndrome was made due to the presence of a p." | 5.91 | A case report of a young boy with low renin and high aldosterone levels induced by Liddle syndrome who was previously misdiagnosed with primary aldosteronism. ( Jin, Y; Qiu, W; Yao, J, 2023) |
"Aldosterone has hypertrophic and profibrotic effects on the heart." | 5.91 | Serum aldosterone effect on left ventricular structure and diastolic function in essential hypertension. ( Al-Hashedi, EM; Juvenal, H; Mohammed, AA; Yu, J; Zhao, X, 2023) |
"Primary aldosteronism (PA) was suspected because of the high plasma aldosterone concentration-to-plasma renin activity ratio." | 5.91 | Coexistence of Pheochromocytoma and Primary Aldosteronism due to Multiple Aldosterone-producing Micronodules in the Ipsilateral Adrenal Gland. ( Fujita, Y; Hino, M; Horikawa, O; Inoue, K; Kageyama, S; Kawauchi, A; Maegawa, H; Nakaizumi, N; Noujima, M; Sasano, H; Sato, D; Ugi, S; Wada, A; Yamazaki, Y; Yonishi, M, 2023) |
"Primary aldosteronism is the most frequent secondary hypertensive disease and is characterized by an elevated risk for cardiovascular disease." | 5.91 | Effect of the interaction between the visceral-to-subcutaneous fat ratio and aldosterone on cardiac function in patients with primary aldosteronism. ( Fujiwara, A; Haruna, A; Haze, T; Hirawa, N; Kawano, R; Kobayashi, Y; Ohki, Y; Ozawa, M; Saka, S; Suzuki, S; Tamura, K, 2023) |
"Primary aldosteronism (PA) is considered the number one aetiology for secondary hypertension." | 5.91 | Duplicated adrenal veins in primary aldosteronism misdiagnosed with ectopic aldosteronoma due to apparent bilateral aldosterone suppression. ( Chen, K; Fan, C; Fang, T; Liu, H; Quan, H; Wei, W; Yu, J; Zhang, Y, 2023) |
"Patients with primary aldosteronism (PA) have a higher risk of cardiovascular disease (CVD) than essential hypertension due to underlying hyperaldosteronism." | 5.91 | High plasma aldosterone concentration is associated with worse 24-h ambulatory blood pressure profile in patients with primary aldosteronism. ( Azushima, K; Haze, T; Kanaoka, T; Kinguchi, S; Kobayashi, K; Kobayashi, R; Morita, R; Sunohara, S; Tamura, K; Toya, Y; Wakui, H, 2023) |
"Primary aldosteronism was diagnosed based on 4 h PAC, adrenal imaging and/or adrenal venous sampling (AVS)." | 5.91 | Using plasma aldosterone concentrations at 1 h of saline infusion test for the diagnosis of primary aldosteronism. ( Chanthanuwat, S; Jannoo, S; Phonanuwong, R; Soonthornpun, S, 2023) |
"Primary aldosteronism (PA) is a well-known cause of secondary hypertension." | 5.91 | Simple standing test without furosemide is useful in the diagnosis of primary aldosteronism. ( Fushimi, Y; Iwamoto, H; Iwamoto, Y; Kaku, K; Kaneto, H; Katakura, Y; Kimura, T; Kusano, T; Mune, T; Nakanishi, S; Ohnishi, M; Sanada, J; Shimoda, M; Takenouchi, H; Tatsumi, F, 2023) |
"Atypical Liddle syndrome can be easily misdiagnosed due to its clinical phenotypes resembling hyperaldosteronism." | 5.91 | Liddle syndrome presenting with normal aldosterone levels: A case report. ( Pan, R; Wang, R; Zhang, R; Zhang, Y; Zhao, Y, 2023) |
"In 2017, the Primary Aldosteronism Surgical Outcome (PASO) investigators proposed consensus criteria for clinical and biochemical outcomes." | 5.72 | Prediction of long-term biochemical cure in patients with unilateral primary hyperaldosteronism treated surgically based on the early post-operative plasma aldosterone value. ( Ishihara, Y; Kaneko, H; Kusakabe, T; Nanba, K; Satoh-Asahara, N; Tagami, T; Tsuiki, M; Umakoshi, H; Yasoda, A, 2022) |
" The results of restricted cubic splines showed the dose-response association between increasing PAC, ARR, decreasing serum potassium, and the risk of WMLs." | 5.72 | Plasma aldosterone concentration is associated with white matter lesions in patients with primary aldosteronism. ( Heizhati, M; Li, N; Liu, Y; Luo, Q; Wang, M; Yao, X; Yuan, Y; Zhu, Q, 2022) |
"We identified patients with aortic dissection and aneurysm with assessed PAC before disease onset from hospital-based electronic database and set as case group." | 5.72 | Higher Plasma Aldosterone Concentrations Are Associated With Elevated Risk of Aortic Dissection and Aneurysm: a Case-Control Study. ( Gan, L; Heizhati, M; Hong, J; Li, N; Lin, M; Luo, Q; Wang, M; Yao, X; Yue, N; Zhang, W; Zhu, Q, 2022) |
"Diagnosis of primary hyperaldosteronism in pregnancy is complicated due to lack of reference ranges for aldosterone, renin and aldosterone-to-renin ratio." | 5.72 | Establishing Reference Ranges for Aldosterone, Renin and Aldosterone-to-Renin Ratio for Women in the Third-Trimester of Pregnancy. ( Grzesiak, M; Horzelski, W; Lewandowski, KC; Lewinski, A; Tadros-Zins, M, 2022) |
"Among 43 patients with primary aldosteronism (PA), thirteen APA patients were enrolled in this study." | 5.72 | Early Renin Recovery After Adrenalectomy in Aldosterone-Producing Adenomas: A Prospective Study. ( Antonini, SR; de Castro, M; Elias, J; Elias, PCL; Mermejo, LM; Molina, CAF; Moreira, AC; Muglia, VF; Tucci, S, 2022) |
"Among those Liddle syndrome patients confirmed by a genetic test, for Test kit A all ARR were screened positive while for test kit B negative." | 5.72 | Liddle syndrome misdiagnosed as primary aldosteronism is caused by inaccurate aldosterone-rennin detection while a novel ( Chen, L; Qu, D; Sun, Q; Wu, C; Xu, X; Yang, Y; Zhao, X, 2022) |
"Ambulatory FST is safe and accurate and can be performed with significantly less healthcare costs compared to FSTin." | 5.72 | Ambulatory fludrocortisone suppression test in the diagnosis of primary aldosteronism: Safety, accuracy and cost-effectiveness. ( Avander, K; Calissendorff, J; Carasel, A; Falhammar, H; Shabo, I; Volpe, C, 2022) |
"Racial differences in obstructive sleep apnea (OSA) and increased aldosterone level may explain the racial disparity in resistant hypertension prevalence." | 5.72 | Relationship Between Risks for Obstructive Sleep Apnea, Resistant Hypertension, and Aldosterone Among African American Adults in the Jackson Heart Study. ( Eaton, CB; Gjelsvik, A; Hall, ME; Koo, P; McCool, FD; Muntner, P, 2022) |
"Primary aldosteronism (PA), including aldosterone and cortisol producing adenoma (A/CPA), is the most common trigger of secondary hypertension." | 5.72 | Two cases of aldosterone and cortisol producing adenoma with different histopathological features: A case report. ( Gao, H; Li, L; Tian, H, 2022) |
"Hypertension is a major health problem common in the elderly people." | 5.72 | Green tea could improve elderly hypertension by modulating arterial stiffness, the activity of the renin/angiotensin/aldosterone axis, and the sodium-potassium pumps in old male rats. ( Akbari, A; Gao, J; Wang, T, 2022) |
"Preeclampsia is a life-threatening disorder of pregnancy unique to humans." | 5.72 | Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia. ( Dimitriadis, E; Menkhorst, E; Santos, L; St-Pierre, Y; Young, MJ; Zhang, JG; Zhou, W, 2022) |
"Primary aldosteronism, eponymously known as Conn's syndrome, has recently gained recognition as the most common cause of endocrine hypertension." | 5.62 | The role of surgery in Conn's syndrome - a case of refractory hypertension secondary to an aldosterone secreting adenoma. ( Bombil, I; Carides, MD; Christofides, C; Sishuba, NT, 2021) |
"Primary aldosteronism was diagnosed." | 5.62 | Hypertension with unilateral adrenal aldosterone and cortisol cosecreting adenoma: A case report. ( Chen, X; Chu, SL; Hu, Z; Luo, FX; Shao, Y; Wang, JG, 2021) |
"Primary aldosteronism is an underdiagnosed cause of hypertension." | 5.62 | Intraindividual Variability of Aldosterone Concentrations in Primary Aldosteronism: Implications for Case Detection. ( Fudim, T; Hundemer, GL; Moussa, M; Sacks, B; Underhill, J; Vaidya, A; Yozamp, N, 2021) |
"Allisartan isoproxil (ALL) is a new angiotensin II receptor blocker and a new antihypertensive drug discovered and developed in China." | 5.62 | Allisartan isoproxil reduces mortality of stroke-prone rats and protects against cerebrovascular, cardiac, and aortic damage. ( Cheng, MH; Fu, FH; Ling, QS; Liu, AJ; Liu, JG; Miao, CY; Tian, JS; Zhang, SL, 2021) |
"Primary aldosteronism (PA) is highly prevalent in hypertensive population." | 5.62 | Determination of adrenal hypersecretion in primary Aldosteronism without aldosterone-production adenomas. ( He, H; Hong, Y; Liu, X; Sun, F; Yan, Z; Zhang, H; Zhao, Z; Zhu, Z, 2021) |
"Residual hypertension was defined as persistent hypertension > 140/90 mmHg or requiring anti-hypertensive medications 1 year after surgery." | 5.62 | Comparison of cystatin C-based and creatinine-based glomerular filtration rate in the prediction of postoperative residual hypertension in aldosterone-producing adenoma patients after adrenalectomy. ( Chang, CC; Chen, CW; Chiu, YW; Hung, CS; Liao, SC; Lin, YH; Liu, KL; Tsai, CH; Tsai, IJ; Wu, VC, 2021) |
"Essential hypertension is a pivotal risk factor for the development of cardiovascular disease (CVD)." | 5.62 | Aldosterone hyperreactivity to acute psychosocial stress induction in men with essential hypertension. ( Ehlert, U; Gideon, A; Sauter, C; von Känel, R; Wirtz, PH, 2021) |
"Primary aldosteronism (PA), as a cause of secondary hypertension, can cause more serious cardiovascular damage than essential hypertension." | 5.62 | A case of primary aldosteronism with a negative aldosterone-to-renin ratio. ( Ding, Y; Liu, F; Wang, L, 2021) |
"Aldosterone has been linked with obesity, metabolic syndrome (MetS), pro-inflammatory, and prothrombotic states; however, most studies relate these indicators with primary aldosteronism (PA), excluding non-PA patients." | 5.51 | The Aldosterone/Renin Ratio Predicts Cardiometabolic Disorders in Subjects Without Classic Primary Aldosteronism. ( Allende, F; Barros, ER; Baudrand, R; Campino, C; Carvajal, C; Fardella, CE; Fuentes, CA; García, H; Kalergis, AM; Martínez-Aguayo, A; Olmos, R; Solari, S; Tapia-Castillo, A; Vecchiola, A, 2019) |
"The aldosterone-treated mice were exposed to NaCl drinking water (1%) during the hormone administration." | 5.48 | Disruption of the with no lysine kinase-STE20-proline alanine-rich kinase pathway reduces the hypertension induced by angiotensin II. ( Alessi, DR; Bobadilla, NA; Castaneda-Bueno, M; Cervantes-Perez, LG; Gamba, G; Jimenez, JV; Rojas-Vega, L; Vazquez, N, 2018) |
"In patients with KCNJ5-mutated APA, left ventricular hypertrophy was significantly decreased by surgical treatment in patients from either Cured or Improved groups, although those patients with wild-type KCNJ5 showed no change." | 5.48 | KCNJ5 mutation as a predictor for resolution of hypertension after surgical treatment of aldosterone-producing adenoma. ( Kitamoto, T; Nishikawa, T; Omura, M; Saito, J; Suematsu, S, 2018) |
"Current threshold values for primary aldosteronism (PA) diagnostic testing are based on measuring aldosterone (PAC) using immunoassays." | 5.48 | Aldosterone LC-MS/MS Assay-Specific Threshold Values in Screening and Confirmatory Testing for Primary Aldosteronism. ( Ahmed, AH; Gordon, RD; Guo, Z; McWhinney, BC; Poglitsch, M; Stowasser, M; Ungerer, JPJ; Wolley, M, 2018) |
"Consecutive patients with diagnosed primary hyperaldosteronism from June 2006 to July 2012 in our center underwent adrenal surgeries without pre-operational adrenal venous sampling (AVS) if all the three criteria were met: (1) round- or oval-shaped occupational lesion of low density after contrast enhancement with diameter >1 cm on CT scan was located in one adrenal gland; (2) unequivocally normal contralateral adrenal gland; (3) serum potassium level lower than 3." | 5.46 | Favorable surgical outcomes of aldosterone-producing adenoma based on lateralization by CT imaging and hypokalemia: a non-AVS-based strategy. ( Cao, X; Feng, X; Li, H; Li, Y; Liu, J; Liu, L; Wei, G, 2017) |
"We described the prevalence of primary aldosteronism in our population before the change and, using the assumption of disease prevalence stability, determined the corresponding ratio cutoffs after the introduction of the new assay." | 5.46 | Novel Approach to Establishing an Aldosterone: Renin Ratio Cutoff for Primary Aldosteronism. ( Chin, A; Kline, GA; Leung, AA; Orton, DJ; Sadrzadeh, H, 2017) |
"All primary aldosteronism patients were diagnosed by autonomous aldosterone secretion using confirmatory tests, and then divided into nPA (n = 130) and primary aldosteronism patients with high PAC (hPA: n = 162) using a PAC cutoff level of less than 443 pmol/l (16 ng/dl), representing the normal upper limit of PAC." | 5.46 | Plasma aldosterone level within the normal range is less associated with cardiovascular and cerebrovascular risk in primary aldosteronism. ( Hamasaki, T; Hashimoto, K; Hayashi, RD; Kajimoto, Y; Kitamura, T; Kouhara, H; Kurebayashi, S; Mukai, K; Murata, M; Nakao, M; Otsuki, M; Shimomura, I; Takeiri, S; Tamada, D; Yamamoto, T, 2017) |
"Eplerenone treatment of patients with PA reduces blood pressure, increases serum potassium level, and improves vascular status." | 5.43 | Eplerenone improves carotid intima-media thickness (IMT) in patients with primary aldosteronism. ( Anzai, K; Kawate, H; Matsuda, Y; Matsuzaki, C; Nomura, M; Ohnaka, K; Sakamoto, R; Shibue, K; Takayanagi, R, 2016) |
"Primary aldosteronism is one of the most common forms of secondary hypertension, but it is often under diagnosed, which leads to the development of cardiovascular damage, and excess costs for long-term drug treatment and management of complications." | 5.43 | The Aldosterone Renin Ratio (ARR) APP as Tool to Enhance the Detection Rate of Primary Aldosteronism. ( Bisogni, V; Rossi, GP, 2016) |
"Our data indicate that in mice with Liddle syndrome, the primary site of increased Na(+) reabsorption is the DCT2/CNT." | 5.43 | In Liddle Syndrome, Epithelial Sodium Channel Is Hyperactive Mainly in the Early Part of the Aldosterone-Sensitive Distal Nephron. ( Bertog, M; Dahlmann, A; Korbmacher, C; Krueger, B; Nesterov, V; Palmisano, R, 2016) |
"Hypertension was resolved less frequently after treatment with RFA compared with laparoscopic adrenalectomy (13 of 36 versus 19 of 27 patients; P = 0·007)." | 5.43 | Radiofrequency ablation compared with laparoscopic adrenalectomy for aldosterone-producing adenoma. ( Chiu, PW; Chow, FC; Chu, CM; Kong, AP; Liu, SY; Ng, EK; Wong, SK, 2016) |
"Prospective studies indicate that hyperaldosteronism is found in 20% of patients with resistant hypertension." | 5.43 | Body Mass Index Predicts 24-Hour Urinary Aldosterone Levels in Patients With Resistant Hypertension. ( Calhoun, DA; Dudenbostel, T; Ghazi, L; Li, P; Liu, M; Oparil, S, 2016) |
"Primary aldosteronism (PA), the most common form of secondary hypertension, causes relevant morbidity." | 5.43 | The Clinical Value of Salivary Aldosterone in Diagnosis and Follow-Up of Primary Aldosteronism. ( Asbach, E; Bidlingmaier, M; Fourkiotis, V; Gerum, S; Lichtenauer, UD; Manolopoulou, J; Quinkler, M; Reincke, M, 2016) |
"The diagnosis of primary aldosteronism (PA) among the older-aged population has posed a crucial challenge." | 5.42 | The value of losartan suppression test in the confirmatory diagnosis of primary aldosteronism in patients over 50 years old. ( Balakrishnan, P; Chen, YM; Chueh, SC; Hsein, YC; Kuo, CC; Wang, MJ; Wu, KD; Wu, VC, 2015) |
"Aldosterone has hypertrophic and profibrotic effects on the heart." | 5.42 | Plasma aldosterone and left ventricular diastolic function in treatment-naïve patients with hypertension: tissue-Doppler imaging study. ( Catena, C; Kraigher-Krainer, E; Pieske, B; Pilz, S; Sechi, LA; Tomaschitz, A; Verheyen, N, 2015) |
"Prehypertension has been associated with adverse cerebrovascular events and brain damage." | 5.40 | Long-term prehypertension treatment with losartan effectively prevents brain damage and stroke in stroke-prone spontaneously hypertensive rats. ( He, DH; Lin, JX; Lin, LM; Ning, RB; Wang, HJ; Xu, CS; Zhang, LM, 2014) |
"Aldosterone was associated with higher SBP only in Hispanics (2." | 5.40 | Association of renin and aldosterone with ethnicity and blood pressure: the Multi-Ethnic Study of Atherosclerosis. ( Allison, MA; Budoff, M; Ix, JH; Jenny, NS; Khaki, AR; McClelland, RL; Rifkin, DE; Watson, K, 2014) |
"In 10 patients with primary aldosteronism, median supine ARRP was 298 (range 48-1222) and ARRD 34 (range 2." | 5.40 | Measurement of plasma renin concentration instead of plasma renin activity decreases the positive aldosterone-to-renin ratio tests in treated patients with essential hypertension. ( Bassani, N; Biganzoli, E; Gritti, A; Lonati, C; Morganti, A, 2014) |
"A correct diagnosis of primary aldosteronism (PA) requires adrenal venous sampling (AVS) for the classification of subtypes (bilateral hyperplasia, BAH, or adenoma, APA)." | 5.40 | Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma. ( Brazzarola, P; Castagna, A; Cecconi, D; Chiecchi, L; D'Alessandro, A; Guarini, P; Gunasekaran, M; Morandini, F; Mulatero, P; Olivieri, O; Pizzolo, F; Veglio, F; Zolla, L, 2014) |
"When hexamethonium was used to assess autonomic control of MAP, no differences in the decrease of MAP in response to ganglionic blockade were detected during the induction." | 5.40 | CNS neuroplasticity and salt-sensitive hypertension induced by prior treatment with subpressor doses of ANG II or aldosterone. ( Beltz, T; Clayton, SC; Johnson, AK; Xue, B; Zhang, Z, 2014) |
"Aldosterone-salt treatment induces not only hypertension but also extensive inflammation that contributes to fibrosis in the rat kidney." | 5.40 | Mizoribine ameliorates renal injury and hypertension along with the attenuation of renal caspase-1 expression in aldosterone-salt-treated rats. ( Doi, S; Doi, T; Kohno, N; Masaki, T; Nakashima, A; Ueno, T; Yokoyama, Y, 2014) |
"Aldosterone excess has a direct negative effect on β-cell function in patients with PA." | 5.39 | Aldosterone excess impairs first phase insulin secretion in primary aldosteronism. ( Adolf, C; Beuschlein, F; Bidlingmaier, M; Fischer, E; Pallauf, A; Reincke, M; Seissler, J; Then, C, 2013) |
"Hyperkalemia is a potentially serious complication following adrenalectomy of aldosterone-producing adenomas (APA)." | 5.39 | Incidence and factors of post-adrenalectomy hyperkalemia in patients with aldosterone producing adenoma. ( Cheng, CJ; Chiang, WF; Lin, MY; Lin, SH; Sun, GH; Sung, CC; Wu, ST, 2013) |
"Aldosterone values were adjusted statistically for age, sex, and the urinary sodium/creatinine ratio." | 5.39 | Bimodal aldosterone distribution in low-renin hypertension. ( Adlin, EV; Braitman, LE; Vasan, RS, 2013) |
"Treatment with aldosterone did not alter mitochondrial respiratory function but accelerated Ca(2+)-induced MPT in SSM, but not IFM, compared with healthy old and young beagles." | 5.39 | Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs: effects of aging and long-term aldosterone infusion. ( Asemu, G; Cox, JW; Dabkowski, ER; Hecker, PA; Hoppel, CL; O'Connell, KA; Rastogi, S; Ribeiro, RF; Sabbah, HN; Shekar, KC; Stanley, WC; Xu, W, 2013) |
"Aldosterone (Aldo) is an important active hormone in the renin-angiotensin-aldosterone system and plays a vital role in the development of hypertension, heart failure and other cardiovascular diseases." | 5.38 | Endogenous aldosterone is involved in vascular calcification in rat. ( Cai, Y; Jia, LX; Qi, YF; Tang, CS; Wang, X; Wu, SY; Xiao, CS; Yu, YR, 2012) |
"Moreover, aldosterone-producing adrenocortical carcinomas without hypertension are exceedingly rare, with only two previously reported cases." | 5.38 | Aldosterone-producing adrenocortical carcinoma without hypertension. ( Bae, SB; Kim, SJ; Kim, YJ; Seo, SW; Song, MS, 2012) |
"Primary aldosteronism caused by an aldosterone producing adrenal tumor/aldosteronoma (APA), is a potentially curable form of hypertension, via unilateral adrenalectomy." | 5.38 | Persistent hypertension after adrenalectomy for an aldosterone-producing adenoma: weight as a critical prognostic factor for aldosterone's lasting effect on the cardiac and vascular systems. ( Carter, Y; Chen, H; Roy, M; Sippel, RS, 2012) |
"1." | 5.37 | Association of the aldosterone synthase gene -344T>C polymorphism with essential hypertension and glucose homeostasis: a case-control study in a Han Chinese population. ( Chen, HY; Gao, X; Li, XM; Ling, Y; Liu, Y; Lu, DR; Lu, ZQ; Yi, QL, 2011) |
"Primary aldosteronism (PA) is associated with a higher incidence of cardiovascular events, probably through mineralocorticoid receptor (MR)-dependent endothelial cell dysfunction, in comparison with essential hypertension (EH)." | 5.37 | Endothelial progenitor cells in primary aldosteronism: a biomarker of severity for aldosterone vasculopathy and prognosis. ( Chen, JW; Chen, YL; Huang, PH; Kuo, CC; Kuo, YS; Lee, BC; Liang, CJ; Lin, SJ; Lin, SL; Lin, YH; Lo, SC; Sun, YY; Tsai, CT; Wu, EL; Wu, KD; Wu, VC, 2011) |
"Resistant hypertension has evolved as an important global health care problem." | 5.37 | What is the role of aldosterone excess in resistant hypertension and how should it be investigated and treated? ( Sica, DA, 2011) |
"Aldosterone plays a role in hypertension, and hypertension is prevalent in patients with insulin resistance." | 5.37 | Plasma aldosterone levels and development of insulin resistance: prospective study in a general population. ( Adachi, H; Enomoto, M; Esaki, E; Fukami, A; Hirai, Y; Imaizumi, T; Jacobs, DR; Kasahara, A; Kumagae, S; Kumagai, E; Nanjo, Y; Ogata, K; Ohbu-Murayama, K; Otsuka, M; Tsukagawa, E; Yokoi, K; Yoshikawa, K, 2011) |
"Primary aldosteronism (PA) is a possible cause of endocrine hypertension." | 5.37 | [Aldosterone/renin ratio in the diagnosis of primary aldosteronism]. ( Catay, E; Honnorat, E; Izquierdo, A; Popescu, BM; Ríos, MC; Rodríguez Cuimbra, S; Sotelo, M, 2011) |
"Hypertension was induced in Cyp1a1-Ren-2 rats through dietary administration of the natural xenobiotic indole-3-carbinol (0." | 5.36 | Inappropriately high circulating and intrarenal angiotensin II levels during dietary salt loading exacerbate hypertension in Cyp1a1-Ren-2 transgenic rats. ( Bürgelová, M; Cervenka, L; Erbanová, M; Husková, Z; Kramer, HJ; Mullins, JJ; Opocenský, M; Thumová, M; Vanourková, Z, 2010) |
"Aldosterone is a prerequisite for this action." | 5.36 | Pathogenesis of hypertension: interactions among sodium, potassium, and aldosterone. ( Büssemaker, E; Hausberg, M; Hillebrand, U; Oberleithner, H; Pavenstädt, H, 2010) |
"Felodipine has a protective effect on the myocardium and kidney as evidenced by decreased perivascular inflammation, myocardial necrosis and fibrosis." | 5.36 | Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats. ( Franco, M; Janicki, JS; Matsubara, BB; Matsubara, LS, 2010) |
"Primary aldosteronism (PA) is a frequent cause of secondary hypertension and is amenable to surgical intervention when it is caused by aldosterone-producing adenoma (APA)." | 5.36 | Predictors of resolution of hypertension after adrenalectomy in patients with aldosterone-producing adenoma. ( Kim, RM; Lee, J; Soh, EY, 2010) |
"Aldosterone and LVH were investigated in 240 and 110 subjects respectively." | 5.36 | Association of HSD3B1 and HSD3B2 gene polymorphisms with essential hypertension, aldosterone level, and left ventricular structure. ( Aoi, N; Izumi, Y; Matsumoto, K; Nakayama, T; Sato, M; Sato, N; Shimodaira, M; Soma, M, 2010) |
"Hyperaldosteronism (PRA < 1 ng x mL(-1) x h(-1) and UAldo > or = 12 microg/24-h) prevalence was 28% and OSA prevalence was 77%." | 5.36 | Severity of obstructive sleep apnea is related to aldosterone status in subjects with resistant hypertension. ( Ahmed, MI; Calhoun, DA; Cofield, SS; Gaddam, KK; Gonzaga, CC; Harding, SM; Oparil, S; Pimenta, E; Thomas, SJ, 2010) |
"Resistant hypertension is a common clinical problem and greatly increases the risk of target organ damage." | 5.35 | Characterization of resistant hypertension: association between resistant hypertension, aldosterone, and persistent intravascular volume expansion. ( Aban, I; Calhoun, DA; Gaddam, KK; Nishizaka, MK; Oparil, S; Pimenta, E; Pratt-Ubunama, MN, 2008) |
"A clear reduction of BP values was recorded after both the first and the second month of treatment with kanrenoate, with the maximal effect obtained when the dosage titration at 100 mg/day was accomplished." | 5.35 | Menopause not aldosterone-to-renin ratio predicts blood pressure response to a mineralocorticoid receptor antagonist in primary care hypertensive patients. ( Blengio, GS; Ciacciarelli, A; Corrocher, R; Falcone, S; Olivieri, O; Pizzolo, F; Signorelli, D, 2008) |
"Weight loss is associated with reduction of blood pressure and of PRA and aldosterone levels in obese hypertensive subjects." | 5.35 | Effect of weight loss through laparoscopic gastric banding on blood pressure, plasma renin activity and aldosterone levels in morbid obesity. ( Dall'Asta, C; Folli, F; Manunta, P; Marchi, M; Paganelli, M; Pizzocri, P; Pontiroli, AE; Vedani, P, 2009) |
"Considering the role of aldosterone in diabetic nephropathy, genetic polymorphism of this gene may contribute to the development and progression of diabetic nephropathy." | 5.35 | Polymorphism of the aldosterone synthase gene is not associated with progression of diabetic nephropathy, but associated with hypertension in type 2 diabetic patients. ( Cha, DR; Kang, YS; Kim, HK; Ko, GJ; Lee, MH; Song, HK, 2008) |
"Primary aldosteronism (PA) may account for as much as 6-20% of cases of refractory hypertension referred to hypertension clinics." | 5.35 | The cutoff value of aldosterone-to-renin ratio for the diagnosis of primary aldosteronism in patients taking antihypertensive medicine. ( Fukuchi, K; Horio, T; Iwanaga, Y; Kamide, K; Kawano, Y; Nakahama, H; Nakamura, S; Nakata, H; Niizuma, S; Yoshihara, F, 2008) |
"Aldosterone promotes renal fibrosis via the mineralocorticoid receptor (MR), thus contributing to hypertension-induced nephropathy." | 5.35 | Hypertension-induced renal fibrosis and spironolactone response vary by rat strain and mineralocorticoid receptor gene expression. ( Camp, JR; Cavallari, LH; Fashingbauer, LA; Geenen, DL; King, ST, 2008) |
"Treatment with camostat mesilate or FOY-251 decreased equivalent current (Ieq) in M-1 cells in a dose-dependent manner and inhibited the protease activity of prostasin in vitro." | 5.35 | Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension. ( Adachi, M; Kakizoe, Y; Kitamura, K; Ko, T; Maekawa, A; Miyoshi, T; Shiraishi, N; Tomita, K; Wakida, N, 2009) |
"Primary aldosteronism (PA) is the most common secondary cause of hypertension that has recently been implicated in alterations of the immune system and progression of cardiovascular disease." | 5.35 | Primary aldosteronism can alter peripheral levels of transforming growth factor beta and tumor necrosis factor alpha. ( Carvajal, CA; Castillo, CR; Contreras, FJ; Fardella, CE; Herrada, AA; Kalergis, AM; Mosso, LM; Stehr, CB, 2009) |
"Normokalaemia does not exclude primary aldosteronism as the underlying cause of hypertension." | 5.35 | [Normokalaemic primary aldosteronism due to an aldosterone-producing adrenal adenoma--Case 06/2009]. ( Guthoff, M; Horger, M; Kirchhoff, K; Kurth, R; Müssig, K; Schnauder, G, 2009) |
"Insulin resistance was estimated by the homeostasis model assessment." | 5.35 | Aldosterone contributes to blood pressure variance and to likelihood of hypertension in normal-weight and overweight African Americans. ( Grim, CE; Kidambi, S; Kotchen, JM; Kotchen, TA; Krishnaswami, S, 2009) |
"The hypertension was not different and virtually superimposable in WT vs." | 5.35 | The role of aldosterone in mediating the dependence of angiotensin hypertension on IL-6. ( Brands, MW; Cannon, JG; Schreihofer, DA; Sturgis, LC, 2009) |
"Liddle's syndrome is an autosomal dominant form of human hypertension, caused by gain-of-function mutations of the epithelial sodium channel (ENaC) which is expressed in aldosterone target tissues including the distal colon." | 5.35 | Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome. ( Bertog, M; Cuffe, JE; Hartner, A; Hilgers, KF; Hummler, E; Korbmacher, C; Porst, M; Pradervand, S; Rossier, BC, 2008) |
"The aldosterone level was comparable in both groups." | 5.35 | Diastolic dysfunction is associated with insulin resistance, but not with aldosterone level in normotensive offspring of hypertensive families. ( Poredos, P; Trojar, A; Zeljko, T; Zizek, B, 2008) |
"In patients with primary aldosteronism, as a whole group, the cut-off value of 69 corresponded to the best compromise value between sensitivity (96%) and specificity (85%), with and without PRA adjustment." | 5.35 | Plasma and urine aldosterone to plasma renin activity ratio in the diagnosis of primary aldosteronism. ( Bardini, M; Bernini, G; Bernini, M; Berti, P; Miccoli, P; Moretti, A; Orlandini, C; Salvetti, A; Taurino, C, 2008) |
"Aldosterone is a mineral corticoid hormone that is produced in response to angiotensin-II, and like angiotensin-II, stimulates inflammation, oxidative stress, and fibrosis by activating nuclear factor-kappaB and activating protein-1." | 5.35 | Crosstalk between the heme oxygenase system, aldosterone, and phospholipase C in hypertension. ( Jadhav, A; Lane, N; Ndisang, JF, 2008) |
"ACTH-induced-hypertension is commonly employed as a model of stress-related hypertension, and despite extensive investigation, the mechanisms underlying elevated blood pressure (BP) are not well understood." | 5.35 | ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit. ( Dostanic-Larson, I; Lasko, V; Lingrel, JB; Loreaux, EL; Lorenz, JN; Paul, RJ; Schnetzer, JR, 2008) |
"Primary aldosteronism (PA) is characterized by the onset of both cardiac and gluco-metabolic alterations." | 5.34 | Aldosterone as a key mediator of the cardiometabolic syndrome in primary aldosteronism: an observational study. ( Agostinelli, L; Boscaro, M; Giacchetti, G; Mantero, F; Rilli, S; Ronconi, V; Turchi, F, 2007) |
"Essential hypertension is a disease multifactorially triggered by genetic and environmental factors." | 5.34 | Analysis of renin-angiotensin-aldosterone system gene polymorphisms in resistant hypertension. ( Barros, M; Bittencourt, I; Cabello, PH; Cordovil, IL; Dolinsky, LC; Freitas, SR; Lima, AB; Moura-Neto, RS, 2007) |
"Primary aldosteronism (PA) has been considered a rare cause of hypertension." | 5.34 | Prevalence of primary aldosteronism among unselected hypertensive patients: a prospective study based on the use of an aldosterone/renin ratio above 25 as a screening test. ( Fogari, E; Fogari, R; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A, 2007) |
"Here we describe a 13-yr-old girl with primary hyperaldosteronism secondary to aldosterone-secreting adenoma." | 5.34 | An additional child case of an aldosterone-producing adenoma with an atypical presentation of peripheral paralysis due to hypokalemia. ( Acikalin, MF; Dinleyici, EC; Dogruel, N; Ilhan, H; Oztelcan, B; Tokar, B, 2007) |
"Recent reports suggesting that primary aldosteronism (PA) is more common than historically thought have often relied on use of the plasma aldosterone concentration (PAC) to plasma renin activity (PRA) ratio (ARR) to identify patients with PA." | 5.33 | Validity of plasma aldosterone-to-renin activity ratio in African American and white subjects with resistant hypertension. ( Calhoun, DA; Cofield, S; Nishizaka, MK; Pratt-Ubunama, M; Zaman, MA, 2005) |
"A total of 25 patients with primary aldosteronism caused by Conn's adenoma, 29 patients with renovascular hypertension, and 29 patients with essential hypertension (EHT) were included in the present study." | 5.33 | Role of aldosterone in left ventricular hypertrophy in hypertension. ( Fujii, K; Iida, M; Matsumura, K; Oka, M; Oniki, H, 2006) |
"Resistant hypertension is common in clinical practice." | 5.33 | Aldosterone and refractory hypertension: a prospective cohort study. ( Calò, LA; Cattelan, F; Ciccariello, L; De Toni, R; Macchini, L; Mascagna, V; Pessina, AC; Realdi, A; Sartori, M; Semplicini, A, 2006) |
"Primary aldosteronism has recently been recognized as the most frequent cause of secondary hypertension." | 5.33 | Confirmatory testing in normokalaemic primary aldosteronism: the value of the saline infusion test and urinary aldosterone metabolites. ( Beuschlein, F; Maser-Gluth, C; Nickel, C; Reincke, M; Rüdiger, F; Schirpenbach, C; Seiler, L, 2006) |
"To screen primary aldosteronism cases with ARR (aldosterone/plasma renin activity, ARR) from patients with hypertension, and to evaluate the diagnosis value of ARR in primary aldosteronism cases and analysis the clinical characters of primary aldosteronism cases." | 5.33 | [Aldosterone/plasma renin activity ratio is a sensitive parameter for screening patients with primary aldosteronism]. ( Liu, ZJ; Shao, JM; Wang, DW; Yan, JT; Zhang, HL, 2006) |
"Liddle's syndrome is a monogenic form of hypertension caused by mutations in the PY motif of the COOH terminus of beta- and gamma-epithelial Na+ channel (ENaC) subunits." | 5.32 | Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin. ( Auberson, M; Hoffmann-Pochon, N; Kellenberger, S; Schild, L; Vandewalle, A, 2003) |
"Increased bioavailability of reactive oxygen species (ROS) has been implicated in the pathogenesis of mineralocorticoid hypertension." | 5.32 | NAD(P)H oxidase inhibitor prevents blood pressure elevation and cardiovascular hypertrophy in aldosterone-infused rats. ( Park, JB; Park, MY; Park, YM; Suh, YL, 2004) |
"The severity of obstructive sleep apnea (OSA) correlates with the difficulty of controlling BP." | 5.32 | Aldosterone excretion among subjects with resistant hypertension and symptoms of sleep apnea. ( Calhoun, DA; Harding, SM; Nishizaka, MK; Zaman, MA, 2004) |
"Obstructive sleep apnea can be detected with a careful history and various sleep studies." | 5.32 | Resistant hypertension, obesity, sleep apnea, and aldosterone: theory and therapy. ( Calhoun, DA; Goodfriend, TL, 2004) |
"Primary hyperaldosteronism is a well-recognized cause of secondary hypertension." | 5.32 | Serum aldosterone and the incidence of hypertension in nonhypertensive persons. ( Benjamin, EJ; Evans, JC; Larson, MG; Levy, D; Meigs, JB; Rifai, N; Vasan, RS; Wilson, PW, 2004) |
"Overweight and obesity are frequently associated with increased plasma levels of aldosterone suggesting a direct link between obesity hypertension and increased mineralocorticoid levels." | 5.32 | Fat cells may be the obesity-hypertension link: human adipogenic factors stimulate aldosterone secretion from adrenocortical cells. ( Arakelyan, K; Bornstein, SR; Ehrhart-Bornstein, M; Krug, AW; Scherbaum, WA, 2004) |
"In patients with primary aldosteronism treated with spironolactone (n = 8), renin escaped suppression and reached very high levels." | 5.31 | Influence of antihypertensive medication on aldosterone and renin concentration in the differential diagnosis of essential hypertension and primary aldosteronism. ( Hahn, EG; Hensen, J; Schobel, H; Seifarth, C; Trenkel, S, 2002) |
"The prevalence of primary aldosteronism (PA) was assessed in a specialized hypertension center." | 5.31 | High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives. ( Davoli, S; Negro, A; Perazzoli, F; Regolisti, G; Rossi, E; Sani, C, 2002) |
"To measure the effects of hyperinsulinemia on serum electrolyte status and associated hormones, and on serum free fatty acid (FFA) concentrations, in patients with essential hypertension." | 5.31 | Serum aldosterone changes during hyperinsulinemia are correlated to body mass index and insulin sensitivity in patients with essential hypertension. ( Haenni, A; Lind, L; Lithell, H; Reneland, R, 2001) |
"Gestational hypertension is a multisystem disorder which always resolves itself after delivery; its primary pathology still remains incompletely clarified." | 5.31 | The renin-aldosterone system during normal and hypertensive pregnancy. ( Creatsas, G; Elsheikh, A; Loutradis, D; Mastorakos, G; Michalas, S; Milingos, S, 2001) |
"The traditional workup for primary aldosteronism is cumbersome and requires discontinuing antihypertensive medications, which is inconvenient and potentially dangerous." | 5.31 | Screening for primary aldosteronism without discontinuing hypertensive medications: plasma aldosterone-renin ratio. ( Ahmad, S; Davidson, RC; Gallay, BJ; Toivola, B; Xu, L, 2001) |
"In 92 patients with chronically treated essential hypertension, two-dimensional and Doppler echocardiographic examinations were performed and LV inflow velocities were measured for evaluation of LV diastolic function." | 5.31 | Influence of plasma aldosterone on left ventricular geometry and diastolic function in treated essential hypertension. ( Horio, T; Iwashima, Y; Kawano, Y; Kuroda, S; Takishita, S, 2002) |
"Also, 17 patients with known primary aldosteronism were retrospectively examined." | 5.31 | Ratio of serum aldosterone to plasma renin concentration in essential hypertension and primary aldosteronism. ( Hahn, EG; Hensen, J; Schobel, H; Seifarth, C; Trenkel, S, 2002) |
"Hyperaldosteronism has been causally linked to myocardial interstitial fibrosis experimentally, but it remains unclear if this link also applies to humans." | 5.31 | Excess aldosterone is associated with alterations of myocardial texture in primary aldosteronism. ( Bertini, A; Cesari, M; Di Bello, V; Ganzaroli, C; Giorgi, D; Mariani, M; Pessina, AC; Rossi, GP; Sacchetto, A; Scognamiglio, R, 2002) |
"The patients with hypertension were enrolled as research objects and the captopril challenge test were carried out when they were hospitalized to screen the cause of hypertension." | 5.30 | [The correlation between the carotid artery plaque and the change of aldosterone level related indexes during captopril challenge test]. ( Lei, YF; Li, M, 2019) |
"Liddle's syndrome is an autosomal dominant form of hypertension that resembles primary hyperaldosteronism, is characterized by the early onset of hypertension with hypokalemia and suppression of both PRA and aldosterone, and is caused by mutations in the carboxyl-terminus of the beta- or gamma-subunits of the renal epithelial sodium channel." | 5.30 | Liddle's syndrome: prospective genetic screening and suppressed aldosterone secretion in an extended kindred. ( Findling, JW; Hansson, JH; Lifton, RP; Raff, H, 1997) |
"A case of primary hyperaldosteronism and cardiomegaly due to a unilateral adrenal adenoma in a newborn is presented." | 5.30 | Hypertensive cardiomegaly caused by an aldosterone-secreting adenoma in a newborn. ( Armanini, D; Cecchetto, G; Fassina, A; Opocher, G; Pozzan, GB; Rigon, F; Zacchello, F, 1997) |
"Aldosterone levels during treatment [13." | 5.30 | Evidence for persistent dysfunction of wild-type aldosterone synthase gene in glucocorticoid-treated familial hyperaldosteronism type I. ( Gartside, MG; Gordon, RD; Stowasser, M; Taylor, WL; Tunny, TJ, 1997) |
"Aldosterone-salt treatment induced, (1) arterial hypertension (+40%) and LV hypertrophy (+60%) without altering LV-fractional shortening, (2) an increase in plasma norepinephrine levels (+262%) and suppression of renin activity." | 5.30 | Modifications of myocardial Na+,K(+)-ATPase isoforms and Na+/Ca2+ exchanger in aldosterone/salt-induced hypertension in guinea pigs. ( Carayon, A; Charlemagne, D; Lechat, P; Mougenot, N; Ramírez-Gil, JF; Trouvé, P, 1998) |
"Cardiac fibrosis is linked to aldosterone-induced hypertension, but the effects on in vivo left ventricular (LV) function are not established." | 5.30 | In vivo left ventricular function and collagen expression in aldosterone/salt-induced hypertension. ( Charlemagne, D; Delcayre, C; Lechat, P; Mougenot, N; Ramirez-Gil, JF; Robert, V; Trouve, P; Wassef, M, 1998) |
"Because essential hypertension is partly genetic, it is possible that altered control of aldosterone synthase gene expression or translation may be responsible." | 5.30 | Aldosterone excretion rate and blood pressure in essential hypertension are related to polymorphic differences in the aldosterone synthase gene CYP11B2. ( Anderson, NH; Connell, JM; Davies, E; Fraser, R; Friel, EC; Holloway, CD; Inglis, GC; Ingram, MC; Morrison, C, 1999) |
"Normotensive primary hyperaldosteronism is exceedingly rare." | 5.30 | Aldosterone-producing adenoma without hypertension: a report of two cases. ( Ghulam, A; Jeunemaitre, X; Lefebvre, J; Provost, F; Ronci, N; Tabarin, A; Vantyghem, MC, 1999) |
"Neurofibromatosis type 1 is a phacomatosis." | 5.30 | A case of neurofibromatosis type 1 with an aldosterone-producing adenoma of the adrenal. ( Alessandri, M; Biagi, P; Campanella, G; Castro, R; Fanciullacci, M; Totteri, A, 1999) |
"Nephrocalcinosis was still present 8 years later and hypertension was recurring obviously as a consequence of increased peripheral resistance." | 5.29 | Aldosterone and testosterone producing adrenal adenoma in childhood. ( Burda, G; Frisch, H; Neuhold, N; Schmitt, K; Schober, E, 1995) |
"In patients with primary aldosteronism and renovascular hypertension the plasma aldosterone level was shown to be an important factor upregulating AT1 receptor mRNA." | 5.29 | Angiotensin II type 1 receptor messenger RNA levels in human blood cells of patients with primary and secondary hypertension: reference to renin profile. ( Murakami, M; Saruta, T; Sato, A; Shibata, H; Suzuki, H, 1994) |
"Spironolactone treatment (50 mg/kg per day) for 7 days in deficient rats restored blood pressure and heart rate to normal levels and significantly reduced sodium levels in erythrocytes and cerebrospinal fluid." | 5.29 | Hypertension induced by a nonpressor dose of angiotensin II in kininogen-deficient rats. ( Katori, M; Kuribayashi, Y; Majima, M; Mizogami, S; Oh-ishi, S, 1994) |
"Arterial hypertension is nowadays no longer considered an isolated disorder of blood pressure regulation but a multifactorial disease with metabolic and cellular deviations." | 5.29 | [Changes in humoral pressor and depressor factors in essential hypertension during lisinopril therapy]. ( Horký, K; Jáchymová, M; Jarolím, M; Jindra, A; Kolár, J; Peleska, J; Savlíková, J; Stolba, P; Umnerová, V; Vorlová, Z, 1994) |
"From these data it emerges that hyperaldosteronism, as observed in these patients with CRI, is a relatively reliable marker of the extent of CRI and may occur independently of the activation of the RAA system, given that other factors, such as orthostatic stimulation, alterations in the acid-base equilibrium, and the degree of aldosterone hepatic and urinary clearance, contribute to its pathogenesis." | 5.29 | [Role of aldosterone in essential arterial hypertension complicated by chronic renal insufficiency]. ( Buracchi, P; Carletti, F; Gennari, C; Lucani, B; Martinelli, M; Nami, R; Panza, F; Pavese, G; Saia, F, 1993) |
"The hyperaldosteronism could not be suppressed by dexamethasone." | 5.29 | [Unilateral autonomous aldosterone production in hyperaldosteronism suppressible by dexamethasone]. ( Haack, D; Jakob, F; Ludwig, J; Rendl, J; Schröder, K; Seufert, J; Vecsei, P, 1993) |
"The reactive fibrosis is thought to be related to MC excess, while cell loss and microscopic scarring may be secondary to enhanced potassium excretion or a cytotoxic effect of aldosterone." | 5.29 | Myocardial fibrosis in the rat with mineralocorticoid excess. Prevention of scarring by amiloride. ( Campbell, SE; Janicki, JS; Matsubara, BB; Weber, KT, 1993) |
"Spironolactone, however, was able to prevent myocardial fibrosis in RHT and aldosterone models of acquired arterial hypertension irrespective of the development of LVH and the presence of hypertension." | 5.29 | Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension. ( Brilla, CG; Matsubara, LS; Weber, KT, 1993) |
"Nilvadipine appears to be an effective hypotensive agent at single daily doses of 8 mg." | 5.28 | Nilvadipine in hypertension with renal dysfunction. ( Albert, FW; Berger, HH, 1992) |
"Aldosterone was analyzed by radioimmunoassay and [4-14C]aldosterone radiometabolites by high-performance liquid chromatography." | 5.28 | Aldosterone metabolism in the isolated perfused liver of R and S hypertension-prone Dahl rats. ( Egfjord, M; Olgaard, K, 1992) |
"Aldosterone-salt treatment produced decreased vascular sensitivity to acetylcholine and nitroprusside in both Wistar and Wistar-Furth rats." | 5.28 | Vascular responsiveness in rats resistant to aldosterone-salt hypertension. ( Bruner, CA, 1992) |
"Captopril treatment should be introduced carefully since not all those patients at risk of hypotension can be identified in advance." | 5.28 | First dose hypotension after captopril; can it be predicted? A study of 240 patients. ( de Boo, T; Dennesen, PJ; Postma, CT; Thien, T, 1992) |
"In conclusion, hypertension is a common problem in acromegaly and at least in part related to similar risk factors in control populations." | 5.28 | Acromegaly and hypertension: prevalence and relationship to the renin-angiotensin-aldosterone system. ( Benker, G; Hirche, H; Kraatz, C; Lüdecke, D; Reinwein, D; Weber, F, 1990) |
"Aldosterone was preferentially metabolized to THA in LRH." | 5.28 | Alterations in aldosterone secretion and metabolism in low renin hypertension. ( Griffing, GT; Melby, JC; Wilson, TE, 1990) |
" The purpose of the present study was to examine whether long-term therapy with ramipril (RA, and ACE inhibitor) would lower blood pressure more effectively and without adverse reactions in combination with the loop diuretics piretanide (PI) or furosemide (FU)." | 5.28 | Loop diuretics combined with an ACE inhibitor for treatment of hypertension: a study with furosemide, piretanide, and ramipril in spontaneously hypertensive rats. ( Baldes, L; Becker, RH; Treudler, M, 1989) |
"1." | 5.28 | Endogenous digoxin-like immunoreactive factor and digitalis-like factor associated with the hypertension of patients receiving multiple alkylating agents as part of autologous bone marrow transplantation. ( Antman, KH; Brena, A; Eder, JP; Graves, SW; Peters, WP; Schryber, SM; Sharma, K, 1989) |
"Bopindolol was given to hypertensive patients in a single daily dose ranging from 1 to 4 mg." | 5.28 | Bopindolol: long-term effects on blood pressure, renal function, plasma renin activity, and plasma aldosterone in mild-to-moderate essential hypertension. ( Modan, M; Rosenfeld, JB; Shohat, J, 1989) |
"Minoxidil was used in 48 patients with AH of varying clinical forms, 19 of those having the malignant AH syndrome." | 5.27 | [Use of angiotensin converting enzyme inhibitor captopril and peripheral vasodilator minoxidil in the treatment of patients with stable and malignant arterial hypertension]. ( Arabidze, GG; Kutsenko, AI; Leshchinskiĭ, PM; Lordkipanidze, NL; Masenko, VP, 1983) |
"Most diagnostic tests for primary aldosteronism use maneuvers to expand the extracellular fluid volume, thereby suppressing the renin-angiotensin system." | 5.27 | Single dose captopril as a diagnostic test for primary aldosteronism. ( Brown, RD; Carollo, ML; Hanson, CS; Kem, DC; Lyons, DF, 1983) |
"Primary aldosteronism is a potentially curable cause of hypertension; it occurs in about 1% of hypertensive patients." | 5.27 | 'Essential' hypertension with hypokalemia. Caused by aldosterone-secreting adrenal adenoma. ( Almog, C; Burke, M; Papo, J; Stavorovsky, M, 1984) |
"Ketanserin is a serotonin antagonist with high affinity for S2-serotonergic receptors, which mediate the vasoconstrictor effects of serotonin." | 5.27 | Ketanserin: a possible tool for studying the role of serotonin in hypertension. ( Boomsma, F; Man in't Veld, AJ; Schalekamp, MA; Wenting, GJ; Woittiez, AJ, 1985) |
"Hyperaldosteronism was associated with the most pronounced deviations in the relationship between stimulants and aldosterone." | 5.27 | [Concentration of adrenocorticotrophic hormone and aldosterone secretion in essential hypertension and hyperaldosteronism]. ( Chikhladze, NM; Pershakova, LP; Shkhvatsabaia, IK; Uchitel', IA; Ustinova, SE, 1985) |
"Enalapril (MK-421) was administered orally as a single dose of 2." | 5.27 | Effect of enalapril on renin, angiotensin converting enzyme activity, aldosterone and prostaglandins in patients with hypertension. ( Genest, J; Gutkowska, J; Hamet, P; Kuchel, O; Larochelle, P; Schiffrin, E, 1985) |
"Mean captopril doses used were similar in both groups." | 5.27 | Effects of converting enzyme inhibition on blood pressure, plasma renin activity (PRA) and plasma aldosterone in hypertensive diabetics compared to patients with essential hypertension. ( Dineen, M; Kelleher, M; Sullivan, PA; Twomey, M, 1985) |
"Treatment with spironolactone alone for 2 months corrected hypertension, hypokalemic alkalosis, and all laboratory and radiologic evidence of rickets and hyperparathyroidism, resulting in acceleration of growth rate." | 5.27 | Spironolactone-reversible rickets associated with 11 beta-hydroxysteroid dehydrogenase deficiency syndrome. ( Arnhold, IJ; Batista, MC; Bloise, W; Kater, CE; Mendonça, BB; Nicolau, W; Rocha, A, 1986) |
" Enalapril in a dosage of 20 mg/day significantly and progressively lowered systolic and diastolic blood pressure at rest, with maximal decreases observed on the 120th day of the study period (P less than 0." | 5.27 | Effects of enalapril maleate on blood pressure, renin-angiotensin-aldosterone system, and peripheral sympathetic activity in essential hypertension. ( Carapelle, E; Carone, MB; Cerasola, G; Contorno, A; Cottone, S; D'Ignoto, G; Grasso, L, 1987) |
"Aldosterone only was elevated in 3 cases, while PRA was elevated in 2." | 5.27 | The pattern of plasma renin activity and aldosterone system in patients with sustained hydronephrosis. ( Ezzat, M, 1987) |
"Hyperaldosteronism in the patients with renal-parenchymatous and essential arterial hypertension was regarded as secondary in a stable and malignant course of arterial hypertension." | 5.27 | [Radioimmunologic determination of aldosterone and renin in the blood in the diagnosis of different forms of arterial hypertension]. ( Khalmuratova, RA; Khamidov, RI; Sattarova, FK, 1987) |
"Minoxidil treatment lowered blood pressure from 178/112 +/- 8/5 mm Hg (means +/- SEM) to 14/95 +/- 6/3 mm Hg." | 5.26 | Treatment of drug-resistant hypertension with minoxidil or angiotensin-converting enzyme inhibitor: blood pressure, renin, aldosterone, and electrolyte responses. ( Baer, L; Radichevich, I; Williams, GS, 1980) |
"Captopril was given in biweekly, doubling doses starting with 25 mg 3 times a day until control of blood pressure was achieved or a total daily dosage of 600 mg was reached." | 5.26 | Dose response in captopril therapy of hypertension. ( Amery, A; Fagard, R; Lijnen, P; Staessen, J; Verschueren, LJ, 1980) |
"Captopril was given to pregnant and nonpregnant animals during the developmental phase of hypertension and to nonpregnant animals with established (4 weeks of treatment) hypertension." | 5.26 | Aldosterone-induced hypertension: effects of a kininase inhibitor. ( Douglas, BH; Evans, TA; Lundy, JH; Parks, BR, 1980) |
"Enalapril was well tolerated." | 5.26 | Effects of enalapril, a new converting enzyme inhibitor, in hypertension. ( Ferguson, RK; Hichens, M; Huber, PB; Irvin, JD; Mojaverian, P; Swanson, BN; Vlasses, PH, 1982) |
"PGF2 alpha was the same in preeclampsia and normotensive pregnancy but higher than in the non-pregnant group." | 5.26 | Prostaglandins, catecholamines, renin and aldosterone during hypertensive and normotensive pregnancy. ( Christensen, NJ; Christensen, P; Johannesen, P; Kornerup, HJ; Kristensen, S; Lauritsen, JG; Leyssac, PP; Pedersen, EB; Rasmussen, AB; Wohlert, M, 1982) |
"Screening tests for primary aldosteronism were compared in 22 patients with this disorder and 140 hypertensive controls." | 5.26 | Simplified screening procedures for primary aldosteronism. Studies on the mechanism of the hyper-responsiveness to furosemide and standing. ( Anderson, GH; Streeten, DH, 1982) |
"Aldosterone excretion was established to be normal in 55." | 5.26 | [Urinary excretion of aldosterone in patients with hypertension]. ( Elenkova, A; Grigorova, R, 1982) |
"Captopril was used in primary and long-term treatment of 40 treatment-resistant hypertensive patients." | 5.26 | Long-term efficacy of captopril in renovascular and essential hypertension. ( Atlas, SA; Case, DB; Laragh, JH; Marion, RM, 1982) |
"Twenty-four patients with primary aldosteronism were studied." | 5.26 | Fludrocortisone suppression test in normal subjects, in patients with essential hypertension and in patients with various forms of aldosteronism. ( Lund, JO; Nielsen, MD, 1980) |
"In primary aldosteronism, high UA and PAC together with suppressed PRA represent an important diagnostic guideline for differentiation from other types of low-renin hypertensions." | 5.26 | Renin-angiotensin-aldosterone system in arterial hypertension. ( Gregorová, I; Horký, K, 1980) |
"Captopril (SQ 14." | 5.26 | Captopril in primary hypertension. Effects related to the renin-angiotensin-aldosterone and kallikrein-kinin systems. ( Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S, 1981) |
"1." | 5.26 | Effect of angiotensin II and converting enzyme inhibitor (captopril) on blood pressure, plasma renin activity and aldosterone in primary aldosteronism. ( Armanini, D; Boscaro, M; Fallo, F; Mantero, F; Opocher, G; Scaroni, C, 1981) |
"Low-renin hypertension was diagnosed by the presence of hypertension, hypokalaemic alkalosis, suppressed plasma renin activity and low plasma aldosterone." | 5.26 | Low-renin, low-aldosterone hypertension and abnormal cortisol metabolism in a 19-month-old child. ( Fiselier, TJ; Honour, JW; Monnens, LA; Otten, BJ; van Munster, PJ, 1982) |
"In most of the patients examined hyperaldosteronism was found, which was attended by an increased percentage of 14C-aldosterone binding with aldosterone binding globulin (ABG) and particularly with glucocorticoid binding globulin (GBG)." | 5.26 | [14C-aldosterone binding by plasma proteins in adolescents with primary arterial hypertension]. ( Bakova, VV; Golov, AG; Kucherenko, AG; Markov, KhM, 1981) |
"Four patients with hyperaldosteronism due to adrenal adenomas served as controls." | 5.26 | The role of ACTH in the episodic release of aldosterone in patients with idiopathic adrenal hyperplasia, hypertension, and hyperaldosteronism. ( Gomez-Sanchez, C; Higgins, JR; Kem, DC; Kramer, NJ; Weinberger, MH, 1976) |
"High aldosterone was more often in patients with high renin, and low levels of aldosterone were usual in those with low and normal renin." | 5.26 | The mechanism of low-renin hypertension: aldosterone response to sodium restriction and upright posture, angiotensin II, ACTH and potassium in patients with hypertension. ( Kondo, K; Matsuki, S; Misumi, J; Nakamura, R; Saito, I; Saruta, T, 1976) |
"These data show that patients with hyperaldosteronism from an adrenal adenoma or hyperplasia have a consistent and exaggerated response to ACTH." | 5.26 | Plasma aldosterone response to ACTH in primary aldosteronism and in patients with low renin hypertension. ( Gomez-Sanchez, C; Higgins, JR; Holland, OB; Kem, DC; Kramer, NJ; Weinberger, MH, 1978) |
""Outpatient hyperkalemia" is a new clinical syndrome in which high serum potassium levels (SK) are found in the outpatient condition returning toward normal without any specific treatment after admission to the hospital." | 5.26 | "Outpatient hyperkalemia" syndrome in renal and hypertensive patients with suppressed aldosterone production. ( Boer, P; Dorhout Mees, EJ; Rado, JP; Simatupang, T, 1979) |
"Experimental toxemia of pregnancy was induced in 8 pregnant monkeys (Macacamulatta) by reducing the abdomiinal aorta to one-third of its original diameter during the last month of gestation." | 5.26 | Experimental toxemia of pregnancy in the monkey, with a preliminary report on renin and aldosterone. ( Abitbol, MM; Driscoll, SG; Gallo, GR; Ober, MB; Pirani, CL, 1977) |
" The findings indicate that different regulatory mechanisms are activated during acute and chronic administration of nifedipine." | 5.26 | Effect of nifedipine on plasma renin, aldosterone and catecholamines in arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Mikkelsen, E; Pedersen, EB; Pedersen, OL, 1979) |
"1." | 5.26 | Blood pressure reduction by incremental infusion of labetalol in patients with severe hypertension. ( Brown, JJ; Cummings, AM; Fraser, R; Lever, AF; Morton, JJ; Richards, DA; Robertson, JI, 1979) |
" The data shows that this dosage of spironolactone gave minor adjustments of the systemic and renal circulation in spite of the consistent changes in BW, PV, PRA and PA." | 5.26 | Haemodynamic effects of treatment and withdrawal of spironolactone in essential hypertension. ( Falch, DK; Johansson, R; Norman, N; Odegaard, AE, 1979) |
"Triamterene was administered in a dose of 100 mg/day for 8 days to 7 patients with essential hypertension." | 5.26 | Effect of triamterene on urinary excretion of immunoreactive prostaglandin E in essential hypertension. ( Abe, K; Chiba, S; Irokawa, N; Ito, T; Otsuka, Y; Saito, K; Sakurai, Y; Sato, M; Yasujima, M; Yoshinaga, K, 1979) |
"Twenty patients suffering from primary hyperaldosteronism were studied." | 5.26 | [The renin-angiotensin-aldosterone system in hypertensive patients. II. Diagnosis of primary hyperaldosteronism]. ( Benguigui, L; Corvol, P; Houde, M; Menard, J; Milliez, P; Tonnelier, M, 1977) |
"Hypertension was produced in 25 rabbits by constricting the right renal artery and leaving the opposite kidney intact (two-kidney hypertension)." | 5.26 | Renin-angiotensin-aldosterone system in experimental renal hypertension in the rabbit. ( Davis, JO; Lohmeier, TE, 1976) |
"Five obvious cases of hyperaldosteronism were found among the 16 low-renin patients." | 5.25 | Abnormally sustained aldosterone secretion during salt loading in patients with various forms of benign hypertension; relation to plasma renin activity. ( Collins, RD; Dowdy, AJ; Gonzales, CM; Luetscher, JA; Nokes, GW; Weinberger, MH, 1970) |
" Prostasin was measured in plasma and urine from type 2 diabetic patients with resistant hypertension (n = 112) randomized to spironolactone/placebo in a clinical trial." | 5.24 | Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin. ( Bistrup, C; Hansen, MR; Hansen, PB; Hinrichs, GR; Jacobsen, IA; Jensen, BL; Kurt, B; Oxlund, C; Schwarzensteiner, I; Stæhr, M; Svenningsen, P; Thuesen, AD; Toft, A, 2017) |
"Angiotensin II receptor blockers (ARBs) have been widely used to treat hypertension and large-scale clinical studies have shown various benefits." | 5.22 | Changeover Trial of Azilsartan and Olmesartan Comparing Effects on the Renin-Angiotensin-Aldosterone System in Patients with Essential Hypertension after Cardiac Surgery (CHAOS Study). ( Arimoto, M; Hata, H; Osaka, S; Sakino, H; Sezai, A; Shiono, M; Yaoita, H, 2016) |
"To address the cardiovascular mechanisms involved in response to an angiotensin II receptor antagonist, losartan, and continuous positive airway pressure (CPAP) as add-on treatment for hypertension and OSA." | 5.22 | Neuroendocrine and Inflammatory Responses to Losartan and Continuous Positive Airway Pressure in Patients with Hypertension and Obstructive Sleep Apnea. A Randomized Controlled Trial. ( Lindberg, C; Manhem, K; Peker, Y; Rosengren, A; Thunström, E; Yucel-Lindberg, T, 2016) |
"This exploratory study reports two plausible loci associated with SBP response to hydrochlorothiazide: TET2, an aldosterone-responsive mediator of αENaC gene transcription; and CSMD1, previously described as associated with hypertension in a case-control study." | 5.20 | TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives. ( Argiolas, G; Barlassina, C; Boerwinkle, E; Braga, D; Carpini, SD; Chapman, AB; Chittani, M; Citterio, L; Condorelli, G; Cooper-Dehoff, RM; Cusi, D; Dominiczak, AF; Donner, KM; Frau, F; Fresu, G; Glorioso, N; Glorioso, V; Gong, Y; Hiltunen, TP; Johnson, JA; Kontula, KK; Lanzani, C; Manunta, P; Melander, O; Ortu, MF; Padmanabhan, S; Piras, DA; Pozzoli, S; Rivera, NV; Salvi, E; Simonini, M; Trimarco, B; Troffa, C; Turner, ST; Velayutham, D; Zaninello, R, 2015) |
"A total of 48 patients with untreated hypertension were randomly assigned to irbesartan (ARB group, n=26) and amlodipine (CCB group, n=22)." | 5.19 | Long-term effects of irbesartan on plasma aldosterone concentration and left atrial volume in hypertensive patients. ( Fujiwara, S; Fukui, M; Goda, A; Hirotani, S; Komamura, K; Koshiba, M; Lee-Kawabata, M; Masaki, M; Masuyama, T; Nakabo, A; Otsuka, M; Sugahara, M; Tsujino, T, 2014) |
"5 mg hydrochorothiazide + 5 mg amlodipine, 86 patients with resistant hypertension were randomized to the add-on 25 mg spironolactone (MRB group, n = 46) or 5 mg ramipril (RASB group, n = 40) groups for 12 weeks." | 5.19 | Greater efficacy of aldosterone blockade and diuretic reinforcement vs. dual renin-angiotensin blockade for left ventricular mass regression in patients with resistant hypertension. ( Azizi, M; Bobrie, G; Chatellier, G; Frank, M; Ménard, J; Perdrix, L; Plouin, PF, 2014) |
"The purpose of this study was to evaluate the effects of spironolactone on dialysis patients with refractory hypertension and possible adverse effects." | 5.19 | Effects of spironolactone on dialysis patients with refractory hypertension: a randomized controlled study. ( Chen, J; Ni, X; Wu, F; Xia, M; Ying, G; Zhang, J; Zhang, P, 2014) |
"The aim was to compare the antiproteinuric effect of aliskiren and ramipril in hypertensive patients with type 2 diabetes and microalbuminuria." | 5.17 | Time course of antiproteinuric effect of aliskiren in arterial hypertension associated with type 2 diabetes and microalbuminuria. ( Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Perrone, T; Preti, P; Zoppi, A, 2013) |
"The primary objective of this study was to evaluate the antihypertensive effect of low dose spironolactone added to triple therapy for resistant hypertension in patients with type 2 diabetes measured by ambulatory monitoring." | 5.17 | Low dose spironolactone reduces blood pressure in patients with resistant hypertension and type 2 diabetes mellitus: a double blind randomized clinical trial. ( Gram, J; Henriksen, JE; Jacobsen, IA; Oxlund, CS; Schousboe, K; Tarnow, L, 2013) |
"We aimed to assess the effect of aliskiren treatment on blood pressure, albuminuria, and kidney function in patients with chronic kidney disease (CKD)." | 5.17 | Efficacy analysis of the renoprotective effects of aliskiren in hypertensive patients with chronic kidney disease. ( Abe, M; Baba, S; Inoshita, A; Maruyama, N; Okada, K; Soma, M; Suzuki, H; Takashima, H, 2013) |
" We conducted an open-label, randomized trial to compare the effects of cilnidipine against those of amlodipine on blood pressure (BP), albuminuria, and plasma aldosterone concentration in hypertensive patients with mild- to moderate-stage chronic kidney disease." | 5.17 | L/N-type calcium channel blocker cilnidipine reduces plasma aldosterone, albuminuria, and urinary liver-type fatty acid binding protein in patients with chronic kidney disease. ( Abe, M; Inoshita, A; Maruyama, N; Okada, K; Soma, M; Suzuki, H; Yoshida, Y, 2013) |
" We wanted to test the hypotheses that amiloride and spironolactone induced potassium retention reduces ambulatory blood pressure (ABP) and central blood pressure (CBP) during baseline conditions and after furosemide and that the tubular transport via the epithelial sodium channels (ENaCs) and aquaporin-2 (AQP2) water channels was increased by furosemide in arterial hypertension." | 5.17 | Effect of amiloride and spironolactone on renal tubular function and central blood pressure in patients with arterial hypertension during baseline conditions and after furosemide: a double-blinded, randomized, placebo-controlled crossover trial. ( Jensen, JM; Larsen, T; Lauridsen, TG; Matthesen, SK; Pedersen, EB; Vase, H, 2013) |
"We measured urinary excretion of AQP2 and ENaC β-subunit corrected for creatinine (u-AQP2(CR), u-ENaC(β-CR)), prostaglandin E2 (u-PGE2) and cyclic AMP (u-cAMP), fractional sodium excretion (FE(Na)), free water clearance (C(H2O)), as well as plasma concentrations of vasopressin (AVP), renin (PRC), angiotensin II (Ang II), aldosterone (Aldo), and atrial and brain natriuretic peptide (ANP, BNP) in 21 patients with essential hypertension and 20 normotensive controls during 24-h urine collection (baseline), and after hypertonic saline infusion on a 4-day high sodium (HS) diet (300 mmol sodium/day) and a 4-day low sodium (LS) diet (30 mmol sodium/day)." | 5.16 | Abnormal increase in urinary aquaporin-2 excretion in response to hypertonic saline in essential hypertension. ( Bech, JN; Graffe, CC; Lauridsen, TG; Pedersen, EB; Vase, H, 2012) |
" In this study, we conducted an open-label and randomized trial to compare the effects of benidipine with those of amlodipine on blood pressure (BP), albuminuria and aldosterone concentration in hypertensive patients with mild-to-moderate stage chronic kidney disease (CKD)." | 5.15 | Benidipine reduces albuminuria and plasma aldosterone in mild-to-moderate stage chronic kidney disease with albuminuria. ( Abe, M; Fujita, T; Maruyama, N; Maruyama, T; Matsumoto, K; Matsumoto, S; Okada, K; Soma, M, 2011) |
"The Ouabain and Adducin for Specific Intervention on Sodium in Hypertension (OASIS-HT) Trial was a phase-2 dose-finding study of rostafuroxin, a digitoxygenin derivative, which selectively antagonizes the effects of endogenous ouabain (EO) on Na+,K+-ATPase and mutated adducin." | 5.15 | Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin. ( Bacchieri, A; Barton, J; Bianchi, G; Citterio, L; de Leeuw, PW; Dłużniewski, M; Espositi, ED; Ferrari, P; Glorioso, N; Januszewicz, A; Kawecka-Jaszcz, K; Lanzani, C; Manunta, P; Milyagin, V; Nikitin, Y; Souček, M; Staessen, JA; Stolarz-Skrzypek, K; Thijs, L; Timio, M; Tykarski, A; Valentini, G, 2011) |
"The Aliskiren in Left Ventricular Hypertrophy (ALLAY) trial randomised 465 hypertensive overweight subjects with LVH to the direct renin inhibitor aliskiren 300 mg, losartan 100 mg or the combination and followed patients for 9 months." | 5.15 | Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertension. ( Appelbaum, E; Dahlöf, B; Desai, A; Lukashevich, V; Pouleur, AC; Prescott, MF; Smith, BA; Solomon, SD; Uno, H, 2011) |
"Participants enrolled in this trial were outpatients with essential hypertension after cardiac surgery who had received candesartan for more than one year." | 5.15 | Effects of olmesartan on the renin-angiotensin-aldosterone system for patients with essential hypertension after cardiac surgery--investigation using a candesartan change-over study. ( Hata, M; Sezai, A; Shiono, M; Soma, M; Unosawa, S; Wakui, S; Yoshitake, I, 2011) |
"The objectives were to determine effects of spironolactone and chlorthalidone on SNA and the role of SNA on diuretic-induced insulin resistance in human hypertension." | 5.14 | Differential effects of chlorthalidone versus spironolactone on muscle sympathetic nerve activity in hypertensive patients. ( Adams-Huet, B; Arbique, D; Auchus, RJ; Menon, DV; Vongpatanasin, W; Wang, Z, 2009) |
" Spironolactone is thought to be an important addition to resistant hypertension (RH) treatment." | 5.14 | Aldosterone excess or escape: Treating resistant hypertension. ( Adriana de Souza, L; Coca, A; Coelho, OR; Ferreira-Melo, S; Martins, LC; Moreno, H; Pimenta, E; Sierra, C; Ubaid-Girioli, S; Yugar-Toledo, JC, 2009) |
"Forty type 2 diabetic patients with hypertension and nephropathy receiving angiotensin receptor II blockers were enrolled and randomly divided into two groups: the efonidipine group was administered efonidipine hydrochloride ethanolate 40 mg/day and the amlodipine group was admin-istered amlodipine besilate 5 mg/day for 12 months." | 5.14 | Protective effects of efonidipine, a T- and L-type calcium channel blocker, on renal function and arterial stiffness in type 2 diabetic patients with hypertension and nephropathy. ( Ban, N; Endo, K; Kawana, H; Miyashita, Y; Nagayama, D; Ohhira, M; Oyama, T; Saiki, A; Sasaki, H; Shirai, K; Yamaguchi, T, 2009) |
"This study was conducted to determine the effects of a tablet combining losartan/hydrochlorothiazide (L/HCTZ) in comparison with losartan alone in Japanese diabetic patients with hypertension." | 5.14 | Safety and benefits of a tablet combining losartan and hydrochlorothiazide in Japanese diabetic patients with hypertension. ( Ichihara, A; Itoh, H; Kinouchi, K; Kurauchi-Mito, A; Sakoda, M, 2009) |
"A total of 50 stable outpatients with essential hypertension who had received candesartan for more than 1 year were randomized into two groups: control group (n=25): continuous candesartan treatment at a stable dose; and olmesartan group (n=25): candesartan (8 mg day(-1)) was changed to olmesartan given at a dose of 20 mg day(-1)." | 5.14 | Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension. ( Fujii, M; Horie, M; Kawahara, C; Nishiyama, K; Tsutamoto, T; Yamaji, M; Yamamoto, T, 2010) |
"A common pharmacologic test for the diagnosis of primary aldosteronism (PA) is the administration of captopril to determine whether an abnormal plasma aldosterone concentration (PAC) to plasma renin activity (PRA) ratio(ARR) persists, although active renin concentration (ARC) may offer advantages with regard to processing and standardization." | 5.14 | Diagnosis of primary aldosteronism: comparison of post-captopril active renin concentration and plasma renin activity. ( Chang, CC; Chang, HW; Chueh, SC; Fang, CC; Ho, YL; Huang, KH; Kuo, CC; Lin, CY; Lin, LY; Lin, SL; Lin, YH; Liu, KL; Tsai, CT; Wang, SM; Wu, KD; Wu, VC; Yen, RF, 2010) |
"The aim of the study was evaluation of spironolactone effect on concentration of endothelin-1 (ET-1 - vasoconstrictive substance produced by endothelial cells) and aldosterone (Ald) and plasma renin activity (PRA) in patients with primary arterial hypertension (AH): group A--smoking patients (11 individuals) in comparison with group B--non-smoking ones (12 individuals)." | 5.14 | [Does spironolactone use at arterial hypertension therapy protect endothelium also in smoking patients?]. ( Kara-Perz, H; Kosicka, T; Perz, S, 2009) |
" We investigated the hypothesis that simvastatin decreased muscle sympathetic nerve activity (MSNA) in 31 hypertensive subjects with hypercholesterolemia (aged 38." | 5.14 | Simvastatin reduces sympathetic activity in men with hypertension and hypercholesterolemia. ( Abramczyk, P; Bidiuk, J; Ciarka, A; Dobosiewicz, A; Gaciong, Z; Lewandowski, J; Siński, M, 2010) |
"Angiotensinogen (AGT) and aldosterone play key roles in the regulation of blood pressure and are implicated in the pathogenesis of cardiovascular diseases." | 5.12 | DNA Methylation of the Angiotensinogen Gene, ( Demura, M; Takeda, Y; Yoneda, T, 2021) |
"In this study we evaluated the effect of a dual blockade with enalapril and losartan on the reduction of overt macroproteinuria and its potential mechanism(s) in hypertensive patients with type 2 diabetes." | 5.12 | Dual blockade of angiotensin II with enalapril and losartan reduces proteinuria in hypertensive patients with type 2 diabetes. ( Hirata, A; Igarashi, M; Kadomoto, Y; Tominaga, M, 2006) |
"The patients with essential hypertension were randomly divided into 2 groups; 1 group was treated with an ARB, candesartan (8 mg/day), for 1 year (ARB group) and other group was treated with the ARB for the first 6 months and with the ARB plus SPRL (25 mg/day) for the next 6 months (combination group)." | 5.12 | Effects of spironolactone during an angiotensin II receptor blocker treatment on the left ventricular mass reduction in hypertensive patients with concentric left ventricular hypertrophy. ( Date, T; Kawai, M; Mochizuki, S; Seki, S; Shimizu, M; Taniguchi, I; Taniguchi, M; Yoshida, S, 2006) |
" It is not known if subjects with a high ratio have aldosteronism or aldosterone-sensitive hypertension is debated but it is important to know whether spironolactone is superior to other diuretics such as bendroflumethiazide in this setting." | 5.12 | Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study. ( Alhashmi, K; Connell, JM; Ford, I; MacDonald, TM; McInnes, GT; McMahon, AD; Parthasarathy, HK; Struthers, AD, 2007) |
"Amlodipine is an effective treatment for hypertension." | 5.11 | Hemodynamic effects of amlodipine, bisoprolol, and lisinopril in hypertensive patients after liver transplantation. ( Alexander, GJ; Brown, MJ; Byrne, CD; Neal, DA; Wilkinson, IB, 2004) |
"Renin, aldosterone, and their interrelation are influenced by circadian rhythms, telmisartan, ramipril, and amlodipine in patients with essential hypertension." | 5.11 | Effects of circadian rhythms, posture, and medication on renin-aldosterone interrelations in essential hypertensives. ( de Champlain, J; Karas, M; Lacourcière, Y; Lamarre-Cliche, M; Larochelle, P; Poirier, L, 2005) |
" We investigated the additive effect of DRSP/E2 versus placebo on 24-h ambulatory blood pressure (BP) in postmenopausal women with hypertension treated with enalapril maleate (ENA)." | 5.10 | Additive effect of drospirenone/17-beta-estradiol in hypertensive postmenopausal women receiving enalapril. ( Alonso, A; Karara, AH; Panzitta, D; Preston, RA; Zhang, P, 2002) |
"The aim of this study was to investigate blood pressure, renal haemodynamics, hormone secretion and the responses to angiotensin II infusion during candesartan cilexetil (candesartan), losartan potassium (losartan) and valsartan treatment in patients with essential hypertension." | 5.10 | Influence of AT1 receptor blockade on blood pressure, renal haemodynamics and hormonal responses to intravenous angiotensin II infusion in hypertensive patients. ( Andersson, OK; Elmfeldt, D; Friberg, PR; Fridman, KU; Wysocki, M, 2002) |
"This study shows that spironolactone improves impaired fibrinolysis in systemic hypertension." | 5.10 | Effect of spironolactone on impaired fibrinolysis of hypertensive patients. ( Aslan, V; Dincer, M; Gulbas, Z; Yalcin, AI, 2002) |
"Black (n = 348) and white (n = 203) patients with mild-to-moderate hypertension were randomized to double-blind treatment with eplerenone 50 mg, the angiotensin II receptor antagonist losartan 50 mg, or placebo once daily." | 5.10 | Efficacy and tolerability of eplerenone and losartan in hypertensive black and white patients. ( Flack, JM; Garthwaite, S; Kleiman, JH; Krause, SL; Oparil, S; Pratt, JH; Roniker, B; Saunders, E; Workman, D; Yang, Y, 2003) |
"One hundred eighteen patients with mild-to-moderate essential arterial hypertension were randomized to treatment with 10 mg/d of amlodipine (group 1), 20 mg/d of quinapril (group 2), or 2 x 50 mg/d of losartan (group 3)." | 5.10 | Effect of amlodipine, quinapril, and losartan on pulse wave velocity and plasma collagen markers in patients with mild-to-moderate arterial hypertension. ( Kawecka-Jaszcz, K; Klocek, M; Rajzer, M, 2003) |
"Eplerenone is a highly selective aldosterone blocking agent, which was recently approved for the treatment of hypertension and has also been shown to reduce mortality in post-myocardial infarction patients with heart failure." | 5.10 | Assessment of the novel selective aldosterone blocker eplerenone using ambulatory and clinical blood pressure in patients with systemic hypertension. ( Carr, AA; Jordan, R; Krause, S; Oigman, W; Roniker, B; White, WB, 2003) |
"After confirming hypertension in the absence of antihypertensive treatment, blood pressure control was achieved by administration of amlodipine at individually adjusted doses." | 5.10 | One year follow-up of hormone replacement therapy with percutaneous estradiol and low-dose vaginal natural progesterone in women with mild to moderate hypertension. ( Castro, I; Reis, FM; Ruschel, S; Spritzer, PM; Vilodre, LC; Vitola, D; Wender, MC, 2003) |
"Previous reports have demonstrated the antihypertensive efficacy of high doses of spironolactone in subjects with primary aldosteronism and, to a lesser degree, subjects with resistant hypertension." | 5.10 | Efficacy of low-dose spironolactone in subjects with resistant hypertension. ( Calhoun, DA; Nishizaka, MK; Zaman, MA, 2003) |
"Patients with mild-to-moderate primary hypertension and left ventricular hypertrophy were randomized in a double-blind study to receive treatment with either the angiotensin II type 1 (AT1) receptor antagonist irbesartan (n = 43), or the beta1-adrenergic receptor blocker atenolol (n = 43)." | 5.10 | Aldosterone synthase (CYP11B2) -344 C/T polymorphism is related to antihypertensive response: result from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial. ( Hägg, A; Kahan, T; Karlsson, J; Kurland, L; Lind, L; Malmqvist, K; Melhus, H; Nyström, F; Ohman, P, 2002) |
" In the present study, we examined the effect on left ventricular hypertrophy of adding a low dose of the mineralocorticoid receptor antagonist spironolactone (25 mg/d) to an angiotensin-converting enzyme inhibitor (enalapril maleate) in patients with essential hypertension." | 5.09 | Effects of spironolactone and angiotensin-converting enzyme inhibitor on left ventricular hypertrophy in patients with essential hypertension. ( Saruta, T; Sato, A; Suzuki, Y, 1999) |
"To study the efficacy and tolerability of a range of valsartan doses in patients with mild-to-moderate hypertension." | 5.09 | Dose-response efficacy of valsartan, a new angiotensin II receptor blocker. ( Chiang, YT; Gatlin, M; Glazer, R; Pool, JL, 1999) |
"To determine the relationship between endothelin-1 (ET-1), human atrial natriuretic peptide (hANP), plasma-renin activity (PRA) and 24-h urinary excretion of aldosterone (U-Ald) in pregnancy-induced hypertension (PIH)." | 5.09 | Plasma human atrial natriuretic peptide, endothelin-1, aldosterone and plasma-renin activity in pregnancy-induced hypertension. ( Bogdanovska, SV; Gerasimovska, BD; Lozance, LA; Maleska, VT; Masin-Paneva, J; Zafirovska, KG, 1999) |
"Since renal sympathetic nerves are involved in the regulation of sodium excretion, we investigated whether treatment with urapidil, an alpha1-adrenoceptor blocking agent which also lowers sympathetic activity, alters sodium excretory capacity in patients with essential hypertension." | 5.09 | Renal haemodynamics and sodium excretory capacity during urapidil treatment in patients with essential hypertension. ( de Leeuw, PW; Fuss-Lejeune, M; Kroon, AA; Lavrijssen, AT; Schiffers, PM, 2000) |
"This multicenter study evaluated the efficacy of candesartan cilexetil, an angiotensin II type 1 receptor antagonist, used alone or in combination with amlodipine or in combination with amlodipine and hydrochlorothiazide in the treatment of patients with moderate-to-severe essential hypertension." | 5.09 | Efficacy of candesartan cilexetil alone or in combination with amlodipine and hydrochlorothiazide in moderate-to-severe hypertension. UK and Israel Candesartan Investigators. ( Antonios, TF; He, FJ; MacGregor, GA; Viskoper, JR, 2000) |
"We examined the effects of the vasodilator peptide adrenomedullin (AM) infused intravenously into subjects with essential hypertension." | 5.09 | Hemodynamic, hormone, and urinary effects of adrenomedullin infusion in essential hypertension. ( Lewis, LK; Nicholls, MG; Richards, AM; Troughton, RW; Yandle, TG, 2000) |
"In this study we investigated the presence of the mutation D147E of CYP11B2 in a group of 128 patients with primary aldosteronism, 68 patients with essential hypertension and increased corticosterone production and in 48 normal volunteers." | 5.09 | Absence of D147E mutation of CYP11B2 gene in hypertensive patients with increased corticosterone and aldosterone production. ( Carra, R; Fallo, F; Filigheddu, F; Glorioso, N; Morra di Cella, S; Mulatero, P; Soro, A; Veglio, F, 2001) |
"The aim of this study was to investigate the effect of short-term treatment with losartan, a selective and competitive angiotensin II (AngII) receptor blocker, on vascular endothelial growth factor (VEGF), active renin and kallikrein activity (KA) in patients with essential hypertension and primary aldosteronism." | 5.09 | Effect of short-term losartan treatment in patients with primary aldosteronism and essential hypertension. ( Atanassova, I; Natchev, E; Orbetzova, M; Tzingilev, D; Zacharieva, S, 2001) |
"To examine the factors that determine the blood pressure response to enalapril and nifedipine monotherapy in the treatment of hypertension associated with non-insulin-dependent diabetes mellitus (NIDDM)." | 5.08 | Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM. ( Chan, JC; Cheung, CK; Cockram, CS; Law, LK; Nicholls, MG; Swaminathan, R, 1995) |
"The antihypertensive effect of the angiotensin-converting enzyme inhibitor trandolapril administered in doses of 1, 2, and 4 mg/d was compared in 207 white patients and 91 black patients with mild to moderate hypertension following a double-blind, randomized, placebo-controlled, parallel study design." | 5.08 | Differing mechanisms of action of angiotensin-converting enzyme inhibition in black and white hypertensive patients. The Trandolapril Multicenter Study Group. ( Gray, JM; Paster, R; Saunders, E; Weir, MR, 1995) |
"The antihypertensive effects of moexipril, a new angiotensin converting enzyme inhibitor, and verapamil-SR as add-on therapy to hydrochlorothiazide (HCTZ) were investigated in patients with moderate to severe (stages II and III) essential hypertension." | 5.08 | Comparison of moexipril, a new ACE inhibitor, to verapamil-SR as add-on therapy to low dose hydrochlorothiazide in hypertensive patients. ( Chrysant, SG; Fox, AA; Stimpel, M, 1995) |
"The effect of calcium channel blocker (CCB), amlodipine (5-10 mg/day) and angiotensin-converting enzyme (ACE) inhibitor, quinapril (10-40 mg/day) on ambulatory blood pressure (ABP), rheological and platelet function in hypertension were compared in this randomised double-blind placebo-controlled cross-over study." | 5.08 | Comparison of amlodipine and quinapril on ambulatory blood pressure and platelet function in hypertension. ( Chang, SM; Chou, TC; Ding, YA, 1995) |
"The effects on blood pressure (BP) and heart rate (HR), at rest and during bicycle exercise, of the vascular selective calcium antagonist felodipine, the cardio-selective beta-blocker metoprolol, and of the two drugs in combination, were assessed in a double-blind, three-way cross-over study comprising 23 patients with essential, mild to moderate hypertension." | 5.08 | Effects of felodipine, metoprolol and their combination on blood pressure at rest and during exercise and on volume regulatory hormones in hypertensive patients. ( Elmfeldt, DB; Gordon, RD; Klemm, SA; Tunny, TJ; Wicks, JR, 1995) |
"In forty six hypertensive patients in whom a high level of clinical suspicion for renovascular hypertension was present on the basis of clinical clues, a captopril test was performed with either 25 mg of captopril or placebo on 2 separate days to determine prospectively the value of the captopril test." | 5.08 | 'Captopril test', with blood pressure and peripheral renin as response variables in hypertensive patients with suspected renal artery stenosis. ( de Leeuw, PW; Lavrijssen, AT; Schiffers, PM; Schreij, G; van Es, PN, 1995) |
"The effects of inhibition of the renin-angiotensin system with quinapril on adrenergic transmission were determined in 18 patients with moderate essential hypertension." | 5.08 | Quinapril ACE-inhibition effects on adrenergic parameters in moderate essential hypertension. ( Bronsoms Artero, J; Matas Serra, M; Matè Benito, G; Mauri Nicolas, JM; Torguet Escuder, P; Vallès Prats, M, 1996) |
"This study compared the effects of 1 year of monotherapy with a calcium-channel antagonist (nilvadipine; NIL), an angiotensin-converting enzyme (ACE) inhibitor (temocapril; TEM), or a new vasodilator (cadralazine; CAD) on left ventricular (LV) hypertrophy in essential hypertension." | 5.08 | The effects of long-term treatment on left ventricular hypertrophy in patients with essential hypertension: relation to changes in neurohumoral factors. ( Inoue, H; Oh-hashi, S; Takata, M; Tomita, S; Ueno, H; Yasumoto, K, 1997) |
" We administered angiotensin II in graded infusion doses to patients with primary hypertension and normotensive controls to study the effects of on circulating kallikreins." | 5.08 | Circulating plasma prekallikrein and tissue kallikrein in normotensive and hypertensive humans: effects of angiotensin II infusion. ( Karlberg, BE; Ohman, KP, 1998) |
"We investigated whether rampiril has selective effects on autonomic control of the circulation in human hypertension, compared with the more hydrophilic ACE inhibitor enalapril." | 5.07 | Does lipophilicity of angiotensin converting enzyme inhibitors selectively influence autonomic neural function in human hypertension? ( Cervenka, JH; Kailasam, MT; Kennedy, BP; O'Connor, DT; Parmer, RJ; Wu, RA; Ziegler, MG, 1994) |
"The effects of two types of angiotensin converting enzyme (ACE) inhibitors, enalapril (long-acting) and captopril (short-acting), on serum electrolytes and circadian rhythm of urinary electrolyte excretions were compared in relation to aldosterone status in patients with essential hypertension and normal renal function." | 5.07 | Crossover comparison of the effects of enalapril and captopril on potassium homeostasis in patients with mild hypertension. ( Abe, I; Fujishima, M; Kobayashi, K; Ohmori, S; Ohya, Y; Takata, Y; Tominaga, M; Ueno, M, 1994) |
"Eight normotensive subjects, eight mild-to-moderate hypertensive type II diabetic patients, and eight nondiabetic patients with essential hypertension were studied before and after 4 weeks of being administered enalapril." | 5.07 | Enhanced pressor responsiveness to norepinephrine in type II diabetes. Effect of ACE inhibition. ( Capelli, M; Ciavarella, A; Mustacchio, A; Ricci, C; Vannini, P, 1994) |
"The present study was performed to clarify changes in plasma levels of 19-hydroxyandrostenedione (19-OH-AD), an amplifier of aldosterone and a possible hypertensinogenic steroid, during several tests for the renin-angiotensin system in 20 patients with aldosterone-producing adenoma (APA) and to determine whether 19-OH-AD participates in the etiology of the hypertension in this disorder." | 5.07 | Low plasma 19-hydroxyandrostenedione levels in patients with aldosterone-producing adenoma. ( Miura, K; Miyazaki, S; Morita, H; Mune, T; Yamakita, N; Yasuda, K, 1993) |
"The authors assessed in 20 subjects with mild or medium severe arterial hypertension basal and stimulated values of plasma renin activity (PRA) and aldosterone before onset of treatment and after 6-week therapy with enalapril (ENAP KRKA) or metoprolol (Vasocardin Slovakofarma)." | 5.07 | [The importance of studying the renin-angiotensin-aldosterone system in essential arterial hypertension in clinical practice. Activity of the renin-angiotensin-aldosterone system during treatment of hypertension with ACE-inhibitors and beta blockers]. ( Chamulová, M; Hrnciar, J; Hrnciarová, M; Kreze, A; Lepej, J; Okálová, D, 1994) |
" 10 with mild uncomplicated and untreated essential hypertension, 10 with essential hypertension under chronic treatment with captopril, 50 mg bid, and 10 with essential hypertension under chronic treatment with atenolol, 100 mg oid, received aspirin, 100 mg oid, and the corresponding placebo for one month, according to a double blind randomized cross-over design." | 5.07 | Hemodynamic and humoral effects of low-dose aspirin in treated and untreated essential hypertensive patients. ( Abdel-Haq, B; Favilla, S; Magagna, A; Salvetti, A; Taddei, S, 1994) |
"Ketanserin, a serotonin-2-receptor antagonist, was administered to 16 patients with mild to moderate essential hypertension in randomized single-blind placebo controlled study." | 5.07 | [Influence of chronic ketanserin therapy on blood pressure and certain humoral and metabolic factors in patients with mild to moderate primary essential hypertension]. ( Berent, H; Brym, E; Czerniewska, E; Januszewicz, W; Knypl, K; Kuçzyńska, K; Wacławek-Maczkowska, J; Wasowska, T; Wocial, B, 1993) |
"The effect of three calcium entry blockers--verapamil, nifedipine and felodipine--on diuresis, natriuresis, the renin-aldosterone axis, and atrial natriuretic peptide (ANP) levels was studied in 30 previously untreated patients with mild to moderate essential hypertension." | 5.07 | The role of atrial natriuretic peptide in the diuretic effect of Ca2+ entry blockers. ( Ezra, D; Peleg, E; Rosenthal, T; Shamiss, A, 1993) |
" After a two-week, placebo run-in phase, 110 patients with mild to moderate hypertension were randomised to receive 10 mg lisinopril or enalapril, or placebo for 4 weeks." | 5.07 | Twenty-four hour blood pressure effect of once-daily lisinopril, enalapril, and placebo in patients with mild to moderate hypertension. ( Dunne, B; Glazer, N; Kostis, JB; Miller, WE; Rector, DJ; Tresznewsky, ON; Whelton, A, 1992) |
" Nine outpatients with mild and moderate hypertension were studied in the Cardiology Service of Vargas Hospital with a D1 agonist, piribedil, at 50-100 mg/day, orally, for 8 weeks, and with a D2 agonist, bromocriptine, at 2." | 5.07 | Comparative effects of dopaminergic agonists on cardiovascular, renal, and renin-angiotensin systems in hypertensive patients. ( Alvarez, R; Luchsinger, A; Morillo, J; Pieretti, OH; Romero, E; Urbina, A; Velasco, M, 1992) |
"The effects of a sustained-release formulation of the calcium antagonist nicardipine on left ventricular (LV) mass, Doppler transmitral velocity profiles and plasma neurohumoral studies were analyzed in patients with mild to moderate systemic hypertension." | 5.07 | Effects of sustained-release nicardipine on regression of left ventricular hypertrophy in systemic hypertension. ( Adler, J; Dittrich, HC; Ong, J; Reitman, M; Weber, M; Ziegler, M, 1992) |
"The short-term effects of atenolol and nifedipine on plasma levels of atrial natriuretic peptide (ANP), plasma renin activity (PRA), and plasma aldosterone (PA) were studied in two groups of patients with uncomplicated essential hypertension." | 5.07 | Short-term effects of atenolol and nifedipine on atrial natriuretic peptide, plasma renin activity, and plasma aldosterone in patients with essential hypertension. ( Bucci, V; Casale, R; Colantonio, D; Desiati, P; Giandomenico, G; Pasqualetti, P, 1991) |
"Nifedipine causes an acute and a sustained reduction in sodium balance in patients with essential hypertension." | 5.07 | Acute and sustained changes in sodium balance during nifedipine treatment in essential hypertension. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR, 1991) |
"11 inhibitor candoxatril in eight patients with untreated essential hypertension on high sodium (350 mmol/day) and low sodium (10 mmol/day) diets." | 5.07 | Dietary sodium and inhibition of neutral endopeptidase 24.11 in essential hypertension. ( Buckley, MG; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR, 1991) |
"A randomized, double-blind, placebo-controlled study was conducted to study the effects of acute and chronic administration of carvedilol in essential hypertension, with special emphasis on renal haemodynamics and function." | 5.06 | Effects of carvedilol on renal function. ( Dupont, AG, 1990) |
"In a double-blind 6 month trial, the cardiac effects of captopril and minoxidil, administered as third step treatments, were compared in 34 men with essential hypertension and diastolic blood pressure greater than 95 mm Hg who were taking 200 mg/day of metoprolol and 80 mg/day of furosemide." | 5.06 | Effects of captopril and minoxidil on left ventricular hypertrophy in resistant hypertensive patients: a 6 month double-blind comparison. ( Chatellier, G; Corvol, P; Dufloux, MA; Julien, J; Menard, D; Menard, J; Plouin, PF; Prasquier, R, 1990) |
"The effects of 6 weeks of treatment with dilevalol 100 mg once daily, or carteolol 10 mg once daily, on renal blood flow (RBF), glomerular filtration rate (GFR) and total renal vascular resistance (TRR) were studied in 10 patients with mild-to-moderate essential hypertension in a randomised cross-over experiment." | 5.06 | Comparison of the renal effects of dilevalol and carteolol in patients with mild to moderate essential hypertension. ( Baba, T; Murabayashi, S; Takebe, K; Tomiyama, T, 1990) |
"The renal, metabolic and antihypertensive effects of enalapril (E) and slow-release verapamil (V) were compared in a 2-month double-blind crossover trial in 22 patients with newly discovered essential hypertension." | 5.06 | Antihypertensive and renal effects of enalapril and slow-release verapamil in essential hypertension. A double-blind, randomized study. ( Fagher, B; Henningsen, N; Hulthén, L; Katzman, P; Thulin, T, 1990) |
"The purpose of the study was to evaluate the effects of a dihydropyridine calcium antagonist, nicardipine (N), on blood pressure (BP) and aldosterone secretion in hypertensive patients (pt) with primary aldosteronism." | 5.06 | [Effect of a calcium inhibitor, nicardipine, on aldosterone secretion in primary hyperaldosteronism]. ( Begasse, F; Chamontin, B; David, D; Salvador, M, 1989) |
"The effects of acute calcium entry blockade by isradipine (IS) and placebo (P) on the haemodynamic and humoral responses to angiotensin II (A II) have been compared in two groups of 9 patients with essential hypertension." | 5.06 | Acute calcium entry blockade inhibits the blood pressure but not the hormonal responses to angiotensin II. ( Amery, A; Fagard, R; Hespel, P; Lijnen, P; Moerman, E; Staessen, J, 1989) |
"The chronic effect of the calcium antagonist nitrendipine was investigated on blood pressure (BP), plasma aldosterone concentration (PAC), plasma renin activity (PRA), and serum potassium in six patients with primary aldosteronism, either due to an (unilateral) aldosterone-producing adenoma (APA; n = 3; age, 44 +/- 4 years; PAC, 312 +/- 96 pg/ml; PRA, less than 0." | 5.06 | Therapeutic value of calcium antagonists in autonomous hyperaldosteronism. ( Ivens, K; Kaufmann, W; Stimpel, M; Volkmann, HP; Wambach, G, 1989) |
" To investigate the contribution of sedation to the cardiovascular effects induced by clonidine, we studied patients with essential hypertension on two separate occasions when similar levels of sedation were induced by clonidine and nitrazepam." | 5.06 | The haemodynamic and hormonal responses after clonidine occur independently of sedation in essential hypertension. ( Kooner, JS; Mathias, CJ; Peart, WS, 1989) |
"To investigate the pathogenetic constellation and its modification by calcium channel blockade in hypertension associated with chronic nonoliguric renal failure, blood pressure (BP), various pressor factors or correlates, cardiovascular responsiveness, and plasma atrial natriuretic peptide (ANP) were assessed in 15 hypertensive patients (serum creatinine 160-715 mumol/l) before and after 6 weeks of intervention with the agent nitrendipine." | 5.06 | Hypertensive dysregulation and its modification by calcium channel blockade in nonoliguric renal failure. ( Bürgisser, E; Ferrier, C; Gnädinger, MP; Jahn, H; Schohn, D; Weidmann, P, 1989) |
"This double-blind placebo controlled study investigated the antihypertensive and humoral effects of nifedipine capsules in patients with essential hypertension inadequately controlled (seated diastolic blood pressure greater than or equal to 95 mm Hg) by hydrochlorothiazide (HCTZ) alone." | 5.06 | Antihypertensive and humoral effects of nifedipine in essential hypertension uncontrolled by hydrochlorothiazide alone. ( Abraham, PA; Halstenson, CE; Opsahl, JA, 1989) |
"The effects of enalapril alone and in combination with the cyclooxygenase inhibitors sulindac and indomethacin on blood pressure (BP), plasma aldosterone, renin activity and converting enzyme activity were evaluated in 29 patients with mild to moderate essential hypertension, 26 of whom had low plasma renin activity." | 5.06 | Antihypertensive effect of enalapril in essential hypertension: role of prostacyclin. ( Hammett, DK; Horton, R; Irvin, J; Oparil, S; Wilkins, LH, 1987) |
"Phenylephrine infusions enhance diuresis and natriuresis both in normal subjects and patients with essential hypertension, whereas they have an opposite effect on urinary aldosterone excretion, decreasing it in normal subjects and enhancing it in hypertensive patients." | 5.06 | [Effects of phenylephrine on atrial natriuretic factor and the renin-aldosterone axis in normal patients and essential hypertensive patients]. ( Cantin, M; Closas, J; Cusson, J; De Léan, A; Genest, J; Gutkowska, J; Hamet, P; Larochelle, P; Thibault, G, 1988) |
"A series of studies were undertaken to assess the effect of oral fenoldopam, a specific DA1 dopamine receptor agonist on blood pressure and renal function in patients with mild essential hypertension." | 5.06 | Studies with fenoldopam, a dopamine receptor DA1 agonist, in essential hypertension. ( Brown, J; Harvey, JN; Lee, MR; Worth, DP, 1986) |
"In order to evaluate the acute effects of urapidil on renal vascular tone and on pressor systems we performed a randomised placebo-controlled crossover study in 8 patients with uncomplicated essential hypertension." | 5.06 | Renal haemodynamic and neurohumoral responses to urapidil in hypertensive man. ( Birkenhäger, WH; de Bruyn, HA; de Leeuw, PW; van Es, PN, 1988) |
"A randomized crossover trial was conducted in 15 patients with essential hypertension to compare the actions of prazosin, a specific alpha 1-adrenoceptor blocker, and ketanserin, an antagonist at alpha 1-adrenergic and serotonin receptors." | 5.06 | Ketanserin and prazosin: a comparison of antihypertensive and biochemical effects. ( Marwood, JF; Mennie, BA; Stokes, GS, 1986) |
"To evaluate the humoral and hemodynamic (both systemic and renal) effects of celiprolol and to assess whether these effects are at least partially due to the activation of dopamine (DA) receptors, 9 out-patients with mild to moderate uncomplicated essential hypertension, without any therapy for at least 3 weeks, received celiprolol (400 mg once daily) and placebo, each for 1 month, according to a double-blind randomized trial pattern." | 5.06 | Systemic and renal hemodynamic effects of celiprolol in essential hypertensives. ( Lucarini, AR; Salvetti, A, 1988) |
"Twenty-seven subjects with essential hypertension were prospectively followed for a minimum of 100 weeks, receiving either enalapril monotherapy or enalapril and hydrochlorothiazide combination therapy." | 5.06 | Humoral effects of long-term oral enalapril therapy. ( Bauer, JH; Reams, GP, 1986) |
"The effect of chronic converting enzyme inhibition with enalapril on the PRA, PRL and plasma aldosterone responses to metoclopramide was studied in 10 patients with mild to moderate essential hypertension." | 5.06 | Enhanced response of plasma prolactin to metoclopramide during chronic converting enzyme inhibition. ( Dupont, AG; Van der Nipen, P; Van Steirteghem, AC; Vanhaelst, L, 1987) |
"The antihypertensive effects of the 5-HT2 receptor antagonist ketanserin were evaluated in 16 patients with uncomplicated essential hypertension." | 5.06 | Antihypertensive response to ketanserin: influence of race and weight. ( Cressman, MD; Ferguson, RK; Gabos, C; Kosoglou, T; Rocci, ML; Vlasses, PH, 1988) |
"The effects of the addition of a calcium entry antagonist, nifedipine (20-mg tablet twice a day), to an angiotensin converting enzyme inhibitor, captopril (25 mg three times a day), and the addition of captopril to nifedipine were observed in two separate studies in patients with essential hypertension." | 5.06 | Captopril and nifedipine in combination for moderate to severe essential hypertension. ( MacGregor, GA; Markandu, ND; Shore, AC; Singer, DR, 1987) |
" To investigate this, 75 out-patients with essential hypertension were treated with chlorthalidone 12." | 5.06 | Plasma renin activity does not predict the antihypertensive efficacy of chlorthalidone. ( Bartolomei, G; Cagianelli, MA; Cinotti, G; Innocenti, P; Loni, C; Papi, L; Pedrinelli, R; Saba, G; Saba, P; Salvetti, A, 1987) |
" In nine patients with essential hypertension, following single and multiple doses of ketanserin, assessments were made of blood pressure and heart rate, QT interval, and pressor responses to phenylephrine and angiotensin II." | 5.06 | Acute and chronic ketanserin in essential hypertension: antihypertensive mechanisms and pharmacokinetics. ( Donnelly, R; Elliott, HL; Meredith, PA; Reid, JL, 1987) |
"After a run-in period of 8 weeks on a regimen of hydrochlorothiazide (HCT, median dosage 75 mg/day), patients with essential hypertension were randomly allocated to continued hydrochlorothiazide therapy (Group I) or additional treatment with amiloride (Group II, median dosage 15 mg/day, or 5 mg per 25 mg hydrochlorothiazide) for the following 12 weeks." | 5.06 | Effects of combined therapy with amiloride and hydrochlorothiazide on plasma and total body potassium, blood pressure, and the renin-angiotensin-aldosterone system in hypertensive patients. ( Dige-Petersen, H; Giese, J; Ibsen, H; Leth, A; Nielsen, MD; Rasmussen, S; Svendsen, UG, 1986) |
"In order to assess the neurohormonal responses to oral administration of two drugs with different antihypertensive mechanisms, and their implications for long-term efficacy, we studied the changes in plasma renin activity, aldosterone, catecholamines and blood pressure after two cross-over periods of treatment with captopril and hydrochlorothiazide for three months in 14 patients with moderate essential hypertension." | 5.06 | Neurohormonal responses to antihypertensive treatment with captopril or hydrochlorothiazide. ( Balcells, A; Gaya, J; Ingelmo, M; Rabinad, E; Rivera, F, 1986) |
"In an open triple crossover study in 8 patients with essential hypertension, the possibility has been investigated of whether the blood pressure lowering effect of hydrochlorothiazide 50 mg once daily was attenuated by co-administration for 4 weeks of ibuprofen 400 mg t." | 5.06 | The influence of ibuprofen, diclofenac and sulindac on the blood pressure lowering effect of hydrochlorothiazide. ( Gribnau, FW; Koopmans, PP; Thien, T, 1987) |
"Blood pressure (BP), plasma electrolytes, renin, aldosterone, angiotensin II (AII) or catecholamines, the chronotropic effects of intravenous isoproterenol, norepinephrine (NE) or AII, the pressor responses to NE or AII, and the relationship between plasma AII and aldosterone concentrations were studied before and after 10 days of dietary supplementation with potassium 100 mmol/day, in normotensive members of normotensive (N = 12) or hypertensive (N = 12) families, and 11 patients with borderline essential hypertension." | 5.06 | Potassium and norepinephrine- or angiotensin-mediated pressor control in pre-hypertension. ( Beretta-Piccoli, C; Bianchetti, MG; Ferrier, C; Weidmann, P, 1987) |
"The efficacy and tolerability of the new ACE-inhibitor enalapril (MK 421) and the beta 1-selective adrenoceptor blocker atenolol for the treatment of primary hypertension were compared in a double blind parallel study." | 5.05 | Enalapril and atenolol in primary hypertension--a comparative study of blood pressure lowering and hormonal effects. ( Karlberg, BE; Ohman, KP, 1984) |
"The hormonal and hypotensive effects of a single oral 10 mg dose of enalapril (MK-421), were assessed by a double-blind randomized trial in 12 subjects with essential hypertension, during a 100 and 40 mmol/day sodium intake." | 5.05 | Effect of dietary sodium on angiotensin-converting enzyme (ACE) inhibition and the acute hypotensive effect of enalapril (MK-421) in essential hypertension. ( Cubela, R; Jackson, B; Johnston, CI, 1984) |
"The possibility of beta-adrenoreceptor hypersensitivity after abrupt withdrawal of long-term therapy (8-18 months) with the slow-release (SR) formulation of oxprenolol (160-320 mg/day) was assessed in six patients with uncomplicated essential hypertension." | 5.05 | Lack of beta-adrenoreceptor hypersensitivity after abrupt withdrawal of long-term therapy with oxprenolol. ( Amann, FW; Bolli, P; Bühler, FR; Burckhardt, D; Meier, M; Raeder, EA; Rogg, H, 1981) |
" In 14 patients with mild to moderate essential hypertension, the effects of bucindolol, hydrochlorothiazide and their combination on blood pressure (BP), heart rate (HR) and parameters of the renin-aldosterone system were compared with those after placebo." | 5.05 | Bucindolol, a beta-adrenoceptor blocker with vasodilatory action: its effect in systemic hypertension. ( Fedder, IL; Ferguson, RK; Rocci, ML; Rotmensch, HH; Soyka, L; Swanson, BN; Vlasses, PH, 1984) |
"The aim of this study was to investigate and compare the effects of two calcium antagonist drugs, verapamil (VER) and nifedipine (NIF), on blood pressure (BP), heart rate (HR), plasma catecholamines (pCA), renin (PRA), plasma aldosterone (pALD), and plasma volume (PV) in a group of patients with mild to moderate essential hypertension." | 5.05 | Antihypertensive and humoral effects of verapamil and nifedipine in essential hypertension. ( Agabiti-Rosei, E; Alicandri, CL; Beschi, M; Castellano, M; Corea, L; Fariello, R; Muiesan, G; Romanelli, G, 1982) |
"The effect of low doses (25 mg three times a day) of captopril was evaluated in 16 patients with mild to moderate essential hypertension, previously uncontrolled by hydrochlorothiazide." | 5.05 | Low-dose captopril: its use in mild to moderate hypertension unresponsive to diuretic treatment. ( Ferguson, RK; Mojaverian, P; Rotmensch, HH; Swanson, BN; Vlasses, PH, 1982) |
"Eight patients with essential hypertension completed a double-blind, randomly allocated crossover comparison of either 5 or 10 mg enalapril maleate, 50 mg hydrochlorothiazide, or their combination administered once daily during sequential two-week periods." | 5.05 | A comparative pilot study of enalapril, a new converting enzyme inhibitor, and hydrochlorothiazide in essential hypertension. ( Ferguson, RK; Irvin, JD; Lee, RB; Swanson, BN; Vlasses, PH, 1982) |
"The effects of captopril and propranolol on blood pressure, heart rate and plasma noradrenaline, renin and aldosterone, and on the responses to changes in posture and to isometric exercise were measured in patients with essential hypertension." | 5.05 | The effect of captopril and propranolol on the responses to posture and isometric exercise in patients with essential hypertension. ( Goodwin, FJ; Holly, JM; Marsh, FP; Sharman, VL; Vandenburg, MJ, 1983) |
"57 years), with primary arterial hypertension, was submitted to two periods of treatment in a cross-over study with spironolactone and potassium canrenoate." | 5.05 | [Clinical study of the efficacy of oral potassium canrenoate and spironolactone in essential arterial hypertension]. ( Fanti, P; Mantellini, R; Sciarra, F; Tosti-Croce, C, 1983) |
"The effects on blood pressure, the renin-angiotensin-aldosterone and the kallikrein-kinin systems were investigated in 32 patients with primary hypertension WHO stage I-II treated with captopril." | 5.05 | Captopril, aldosterone and urinary kallikrein in primary hypertension. ( Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S, 1983) |
"The metabolic effects of piretanide (2 x 6 mg daily) were compared with those of hydrochlorothiazide, in doses of 2 x 25 mg or 2 x 50 mg daily, in a double-blind study consisting of three parallel groups totalling 15 patients with uncomplicated essential hypertension." | 5.05 | The effects of piretanide on catecholamine metabolism, plasma renin activity and serum aldosterone: a double-blind pilot comparison against hydrochlorothiazide in patients with essential hypertension. ( Bückert, C; Kirsten, R; Verho, M, 1984) |
"Thirty-two patients with moderate to severe essential hypertension whose supine diastolic blood pressure (SDBP) was greater than or equal to 95 mm Hg following 2 weeks' treatment with the optimal dosage of beta blocker-diuretic combination were randomly assigned to the addition of either captopril 25 mg or 50 mg b." | 5.05 | Efficacy of low-dose captopril given twice daily to patients with essential hypertension uncontrolled by a beta blocker plus thiazide diuretic. ( Agabiti-Rosei, E; Alicandri, C; Boni, E; Cinquegrana, A; Fariello, R; Montini, E; Muiesan, G; Muiesan, ML; Zaninelli, A, 1984) |
"Thirty-two patients with primary hypertension were studied in a double-blind cross-over comparison between the cardioselective beta 1-blocking agent atenolol and the combined alpha- and beta-blocking agent labetalol." | 5.05 | Antihypertensive and metabolic effects of increasing doses of atenolol and labetalol. A comparative study in primary hypertension. ( Henningsen, NC; Karlberg, BE; Nilsson, OR; Thulin, T, 1982) |
"Twenty-four patients with moderate to severe hypertension were treated for four weeks with captopril, an oral inhibitor of angiotensin-converting enzyme." | 5.05 | Captopril in essential hypertension; contrasting effects of adding hydrochlorothiazide or propranolol. ( Banks, RA; Bayliss, J; Jones, JC; MacGregor, GA; Markandu, ND; Roulston, JE, 1982) |
"The effects of amiloride hydrochloride on thiazide-induced hypokalemia were evaluated." | 5.05 | Response of thiazide-induced hypokalemia to amiloride. ( Chan, L; Maronde, RF; Milgrom, M; Vlachakis, ND, 1983) |
"Blood pressure, cardiac output, plasma volume, renin, and aldosterone were measured in 13 patients with essential hypertension on placebo and after 1, 4, and 12 wk on hydrochlorothiazide 100 mg daily." | 5.05 | Hemodynamic changes during long-term thiazide treatment of essential hypertension in responders and nonresponders. ( Man in 't Veld, AJ; Schalekamp, MA; van Brummelen, P, 1980) |
"The magnitude and duration of the antihypertensive effect of nifedipine were studied in 7 cases of moderate essential hypertension." | 5.05 | Antihypertensive effect of fractionated sublingual administration of nifedipine in moderate essential hypertension. ( Bonnet, F; Corvol, P; Thibonnier, M, 1980) |
"Captopril (SQ 14 225), an orally active inhibitor of angiotensin converting enzyme, was evaluated in the treatment of primary (essential) hypertension in a placebo-controlled long-term study." | 5.05 | Captopril, an orally active converting enzyme inhibitor, in the treatment of primary hypertension. A controlled long-term study with reference to initial plasma renin activity. ( Asplund, J; Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S, 1981) |
"In a single-dose crossover study Captopril (SQ 14225), 1 mg/kg body weight, and Nifedipine (Bay a 1040) 20 mg were administered orally to 12 hospitalized patients with essential hypertension (Stage 1 or 2, W." | 5.05 | Antihypertensive and hormonal effects of single oral doses of captopril and nifedipine in essential hypertension. ( Corvol, P; Menard, J; Milliez, P; Sire, O; Soto, ME; Thibonnier, M, 1981) |
"Thirty patients with mild or moderate essential hypertension, and a fixed elevation of diastolic blood pressure, were randomly allocated to three groups and treated with propranolol 40 mg x 4 (Group 1), 80 mg x 4 (group 2) and 160 mg x 4 (Group 3)." | 5.05 | Correlation between propranolol in plasma and urine, renin-aldosterone system and blood pressure in essential hypertension. ( Andreasen, F; Bjerregaard, P; Kornerup, HJ; Pedersen, EB; Pedersen, OL, 1981) |
"In a double-blind crossover study, the antihypertensive effect of hydrochlorothiazide alone and in combination with the beta blocker acebutolol was assessed in 18 patients suffering from mild to moderate hypertension." | 5.05 | Merits of adding a beta blocker (acebutolol) to a diuretic (hydrochlorothiazide) in the treatment of hypertension. ( Belleau, LJ; Brossard, JJ; Lebel, M, 1982) |
"Sixteen patients with essential hypertension completed a double blind factorial trial comparing the effects of indapamide (2." | 5.05 | Effects of once daily indapamide and pindolol on blood pressure, plasma aldosterone concentration and plasma renin activity in a general practice setting. ( Bune, AJ; Chalmers, JP; Graham, JR; Grygiel, JJ; West, MJ; Wing, LM, 1982) |
"A double-blind, cross-over study in 16 patients with essential hypertension was carried out, to evaluate any possible interference by indomethacin, a known prostaglandin-synthetase inhibitor, with the antihypertensive effect of oxprenolol, a non-selective beta-adrenoceptor blocking agent." | 5.05 | Interaction between oxprenolol and indomethacin on blood pressure in essential hypertensive patients. ( Arzilli, F; Beggi, P; Motolese, M; Pedrinelli, R; Salvetti, A, 1982) |
" Since ketanserin, a more specific 5-HT2-serotoninergic (5-HT2) antagonist, has been shown to affect aldosterone secretion in essential hypertension, we have further investigated this mechanism by injecting ketanserin (10 mg i." | 5.05 | Effect of ketanserin in primary aldosteronism. ( Armanini, D; Boscaro, M; D'Agostino, D; Mantero, F; Opocher, G; Rocco, S, 1985) |
"To determine if food reduces the hemodynamic and humoral effects of captopril in patients with essential hypertension, we performed two studies." | 5.05 | Influence of food on acute and chronic effects of captopril in essential hypertensive patients. ( Abdel-Haq, B; Graziadei, L; Magagna, A; Pedrinelli, R; Salvetti, A; Stornello, M; Taddei, S, 1985) |
" To assess the effect of potassium repletion in hypokalemic hypertension, we administered either potassium chloride, 60 mmol per day, or placebo tablets, each for six weeks, in a randomized, double-blind, crossover trial to 16 hypertensive patients who had diuretic-induced hypokalemia and who continued to take a constant amount of diuretic." | 5.05 | Potassium supplementation in hypertensive patients with diuretic-induced hypokalemia. ( Carnegie, A; Heller, JA; Kaplan, NM; Raskin, P; Simmons, M, 1985) |
"To determine the effects of potassium on blood pressure and factors affecting blood pressure, we conducted a randomized, placebo controlled trial of a potassium chloride-based substitute for table salt in 23 patients with mild to moderate essential hypertension." | 5.05 | Effects of potassium on sodium balance, renin, noradrenaline and arterial pressure. ( Barnett, P; Cumming, AM; Hutcheson, MJ; Semple, PF; Zoccali, C, 1985) |
"Renal plasma flow, glomerular filtration rate plasma angiotensin II, aldosterone and arginine vasopressin, free water clearance, blood pressure and body weight in 11 patients with mild to moderate hypertension were determined at the end of consecutive 6 week periods of administration of placebo and verapamil up to 120 mg t." | 5.05 | Effect of verapamil on renal plasma flow, glomerular filtration rate and plasma angiotensin II, aldosterone and arginine vasopressin in essential hypertension. ( Danielsen, H; Pedersen, EB; Sørensen, SS; Thomsen, OO, 1985) |
"Effect of long-term administration of propranolol was studied in 90 unselected patients with essential hypertension." | 5.04 | [Treatment of essential hypertension with propranolol (author's transl)]. ( Braun, B; Klaus, D; Klumpp, F; Lemke, R; Zehner, J, 1976) |
" Captopril was shown to be as effective as hydrochlorothiazide in lowering the blood pressure in patients with moderately severe essential hypertension." | 5.04 | Hormonal changes with long-term converting-enzyme inhibition by captopril in essential hypertension. ( Johnston, CI; Matthews, PG; McGrath, BP, 1979) |
"Eighteen patients with diastolic hypertension (100 to 120 mm Hg), in addition to propranolol, 160 mg daily, and hydrochlorothiazide, 100 mg daily, received progressively increased doses of either minoxidil or placebo in a double-blind crossover study." | 5.04 | Effect of minoxidil on blood pressure and hemodynamics in severe hypertension. ( Bryan, RK; Hoobler, SW; Purdy, JM; Rosenzweig, J; Weller, JM, 1977) |
"A double-blind study of hydrochlorothiazide and spironolactone, alone and in combination, was conducted in 49 patients with mild-to-moderate essential hypertension after a 4-wk placebo washout period." | 5.04 | Hydrochlorothiazide and spironolactone in hypertension. ( Schrijver, G; Weinberger, MH, 1979) |
" Plasma renin activity (PRA), the daily urinary excretion of aldosterone (dU-Aldo) and electrolytes were studied before and during dihydralazine therapy (25 mg 3 times daily)." | 5.04 | The renin-aldosterone system in dihydralazine therapy during hypertensive pregnancy. ( Lammintausta, R, 1978) |
"The antihypertensive effect of the selective beta-1-adrenoceptor blocker, metoprolol, administered once daily was evaluated in 32 patients with primary hypertension." | 5.04 | Once-daily metoprolol in primary hypertension. ( Karlberg, BE; Nilsson, O; Nitelius, E; Tolagen, K; Waern, U, 1979) |
" Four different doses of labetalol (150, 300, 600 and 900 mg/day) were given for 1 week to each of four groups of patients with essential hypertension (six patients for each group)." | 5.04 | Effect of increasing doses of labetalol on blood pressure, plasma renin activity and aldosterone in hypertensive patients. ( Arzilli, F; Pedrinelli, R; Salvetti, A; Sassano, P, 1979) |
"15 patients who had benign, uncomplicated essential hypertension, were treated with chlorthiazide (500 mg twice a day) with or without propranolol (10--20 mg 4 times a day), and the effect of the treatment on plasma renin activity (PRA), urinary aldosterone excretion, total body potassium (TBK) and plasma sodium and potassium was evaluated." | 5.04 | The renin-aldosterone system and thiazide-induced depletion of total body potassium in essential hypertension. ( Carroll, HJ; Oh, MS, 1978) |
" Serial measurements of plasma renin activity (PRA), plasma aldosterone concentration (PA) and blood pressure were performed overnight in patients with borderline (group 1) and sustained essential hypertension (group 2) before and after acute and chronic administration of either propranolol or pindolol." | 5.04 | Differential effects of acute and chronic beta-adrenoreceptor blockade on blood pressure and the renin-angiotensin-aldosterone system in essential hypertension. ( Gramann, W; Kolloch, R; Krück, F; Stumpe, KO; Vetter, H, 1976) |
"Furosemide and the prostaglandin synthetase inhibitor, indomethacin, were administered singly and in combination to four normal subjects and six patients with essential hypertension in order to determine whether the antihypertensive, natriuretic and other effects of furosemide could be altered by inhibition of prostaglandin synthesis." | 5.04 | Antagonism of the effects of furosemide by indomethacin in normal and hypertensive man. ( Babej, M; Bentzel, CJ; Hysert, PE; Lee, JB; Mookerjee, BK; Patak, RV, 1975) |
"To review comparative efficacy and tolerability data between the two main mineralocorticoid receptor antagonists (MRAs), spironolactone and eplerenone, in patients with resistant hypertension (HTN)." | 5.01 | Eplerenone Versus Spironolactone in Resistant Hypertension: an Efficacy and/or Cost or Just a Men's Issue? ( Manolis, AA; Manolis, AS; Manolis, TA; Melita, H, 2019) |
" Diagnosis relies on a triad of hypertension, hypokalemia and suppressed plasma aldosterone levels, plus an abnormal urinary cortisol to cortisone ratio, either free steroid or metabolites." | 4.95 | Apparent mineralocorticoid excess. ( Funder, JW, 2017) |
"Animal studies point to a small increase in plasma and cerebrospinal fluid (CSF) [Na], a small decrease in CSF [K], and increased levels of circulating angiotensin II, aldosterone, and endogenous ouabain as the central signals evoking hypertension." | 4.95 | Sodium and potassium in the pathogenesis of hypertension: focus on the brain. ( Adrogué, HJ; Madias, NE, 2017) |
" It will consider the relationship between obesity and leptin resistance and sympathetic signaling; the role of obstructive sleep apnea in resistant hypertension; and the role of aldosterone in resistant hypertension." | 4.90 | Resistant hypertension in diabetes mellitus. ( Bayliss, G; D'Elia, JA; Weinrauch, LA, 2014) |
" Angiotensin II and aldosterone often collaborate in pathological situations to induce hypertrophy of cardiomyocytes, vascular inflammation, perivascular and interstitial fibrosis, and microvascular rarefaction." | 4.89 | Aldosterone mediates cardiac fibrosis in the setting of hypertension. ( Azibani, F; Chatziantoniou, C; Delcayre, C; Fazal, L; Samuel, JL, 2013) |
"(2) In RALES, low-dose spironolactone in addition to standard of care, produced a 30% improvement in survival in progressive heart failure, commonly assumed to reflect deleterious effects of aldosterone, with spironolactone competing with aldosterone for cardiac mineralocorticoid receptors." | 4.86 | Aldosterone, hypertension and heart failure: insights from clinical trials. ( Funder, JW, 2010) |
" Angiotensin II, the principal effector peptide of the RAAS, has far-reaching effects on vascular structure, growth and fibrosis, and is a key regulator of vascular remodeling and inflammation." | 4.83 | Role of the renin-angiotensin-aldosterone system in vascular remodeling and inflammation: a clinical review. ( Duprez, DA, 2006) |
" However, although aldosterone receptor antagonism reduces mortality in patients with congestive heart failure, the progestational and antiandrogenic side effects of the nonspecific aldosterone receptor antagonist, spironolactone, have limited its usefulness in the treatment of hypertension." | 4.82 | Eplerenone: cardiovascular protection. ( Brown, NJ, 2003) |
"The pathogenic role of angiotensin II (ANG II), dietary sodium chloride, sympathetic activation, obesity and aldosterone in the development of structural vascular changes (SVCs) in hypertension is considered from three perspectives (criteria): their utility in predicting hypertension and its complications (predictability); the effect of their inhibition or removal on the reversal of SVCs (reversibility); and their ability to induce SVCs in experimental animals (reproducibility)." | 4.82 | Pathogenesis of structural vascular changes in hypertension. ( Simon, G, 2004) |
" The selective aldosterone blocker, eplerenone (Inspra), is under development for human therapeutic use for treatment of hypertension and heart failure post-myocardial infarction (MI)." | 4.82 | Aldosterone target organ protection by eplerenone. ( McMahon, EG; Rocha, R; Rudolph, AE, 2004) |
" Spironolactone and eplerenone are the mineralocorticoid receptor (MR) antagonists currently available for the treatment of hypertension." | 4.82 | Mineralocorticoid receptor antagonists and hypertension: is there a rationale? ( Gumieniak, O; Williams, GH, 2004) |
" This review summarizes the effects of vasopressin on Na+ transport mediated by the amiloride-sensitive epithelial sodium channel (ENaC) and the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel in immortalized or primary cultured cortical collecting duct cells, expressing either the wild-type ENaC subunits, or mutations, or deletions of the PY domain of the beta- or gamma-ENaC subunits responsible for Liddle's syndrome, an inherited form of hypertension due to excessive salt absorption." | 4.82 | [Regulation by vasopressin of NaCl absorption in the renal collecting duct]. ( Vandewalle, A, 2005) |
" The 30% improvement in mortality (and 35% in morbidity) seen in the RALES trial with the addition of low-dose spironolactone to best practice therapy in moderate to severe heart failure, similarly points to an unrecognized role for aldosterone in the pathophysiology of heart failure." | 4.81 | Mineralocorticoid receptors and pathophysiological roles for aldosterone in the cardiovascular system. ( Funder, JW; Young, MJ, 2002) |
"In a 16-week study, eplerenone was more effective than placebo or losartan in lowering systolic blood pressure (BP) and diastolic BP in black patients with mild to moderate hypertension." | 4.81 | Clinical implications of aldosterone blockade. ( Weber, MA, 2002) |
" The therapeutic efficacy of spironolactone (Pharmacia Corp) in severe chronic heart failure is established." | 4.81 | The role of aldosterone receptor blockade in the management of cardiovascular disease. ( Krum, H; Liew, D, 2002) |
"Until recently, spironolactone was considered only as an antagonist at the aldosterone receptors of the epithelial cells of the kidney and was used clinically in the treatment of hyperaldosteronism and, occasionally, as a K(+)-sparing diuretic." | 4.81 | The spironolactone renaissance. ( Brown, L; Doggrell, SA, 2001) |
" A provisional diagnosis of Liddle's syndrome was established and the patient was successfully treated with triamterene." | 4.80 | Liddle's syndrome in an elderly woman. ( Furukawa, K; Harada, T; Ikeda, S; Iwasaki, T; Kohno, S; Matsushita, M; Matsushita, T; Miyahara, Y; Miyazaki, M; Naito, T; Ogata, H; Ohzono, Y; Yakabe, K; Yamaguchi, K, 1998) |
" Recent studies, however, have demonstrated that in several forms of chronic hypertension caused by aldosterone, angiotensin II (AngII), vasopressin, or norepinephrine and adrenocorticotropin, increased renal arterial pressure is essential for maintaining normal excretion of sodium and water in the face of reduced renal excretory capability." | 4.77 | Regulation of arterial pressure: role of pressure natriuresis and diuresis. ( Coleman, TG; Guyton, AC; Hall, JE; Mizelle, HL; Woods, LL, 1986) |
"Only recently approved for use in the treatment of hypertension in the US, the beta-adrenergic receptor blocking compound propranolol has been used elsewhere for this purpose since 1964." | 4.75 | Pathophysiology of propranolol in hypertension. ( Frohlich, ED, 1977) |
"The antihypertensive effect of intravenous (acute) and oral (long-term) beta-adrenergic blockade with propranolol or pindolol was evaluated in 46 male patients with either borderline (group I; 23 patients) or sustained (group II; 23 patients) essential hypertension." | 4.75 | Acute and long-term studies of the mechanisms of action of beta-blocking drugs in lowering blood pressure. ( Gramann, W; Higuchi, M; Kolloch, R; Krück, F; Ressel, C; Stumpe, KO; Vetter, H, 1976) |
"Hydralazine, doxazosin, and verapamil are currently recommended by the Endocrine Society as acceptable bridging treatment in those in whom full cessation of antihypertensive medication is infeasible during screening for primary aldosteronism (PA)." | 4.31 | The Effects of Verapamil, Hydralazine, and Doxazosin on Renin, Aldosterone, and the Ratio Thereof. ( Alnazer, RM; de Leeuw, PW; Kroon, AA; Veldhuizen, GP, 2023) |
" It has been reported that sPRR functions as an important regulator of intrarenal renin contributing to angiotensin II (ANG II)-induced hypertension." | 4.31 | Mutagenesis of the cleavage site of (pro)renin receptor abrogates aldosterone-salt-induced hypertension and renal injury in mice. ( Chen, Y; Fu, Z; Kaewsaro, K; Lambert, J; Yang, T; Zheng, H, 2023) |
"The authors sought to determine the relationship of circulating angiotensinogen levels to ethnicity, sex, BP, incident hypertension, and prevalent hypertension in a modern sex-balanced ethnically diverse cohort." | 4.31 | Blood Levels of Angiotensinogen and Hypertension in the Multi-Ethnic Study of Atherosclerosis (MESA). ( Brambatti, M; Carlisle, SM; DeFilippis, AP; Kahlon, T; Michos, ED; Morgan, ES; Mostacero, DO; Mousavi, H; Mullick, AE; Ouyang, P; Shah, SJ; Tami, Y; Trainor, PJ; Tsimikas, S, 2023) |
" In our study, we studied if continuous treatment with a mineralocorticoid receptor antagonist, spironolactone (30 mg/kg/day) for 20 days can: 1) attenuate hypertension development and restore inverted 24-h BP rhythm in hypertensive transgenic (mRen-2)27 rats (TGR) measured by telemetry; 2) improve function of the kidneys and heart; 3) be protective against high salt load (1% in water) by mitigating oxidative injury and improving kidney function." | 4.31 | Mineralocorticoid receptor blockade protects the kidneys but does not affect inverted blood pressure rhythm in hypertensive transgenic (mRen-2)27 rats. ( Kopkan, L; Majzunova, M; Molcan, L; Sutovska, H; Sykora, M; Zeman, M, 2023) |
" The medical records of diabetic cats were searched for the keywords 'hypertension', 'blood pressure', 'amlodipine', 'benazepril' and 'telmisartan' to identify cats with SH, which was defined as systemic arterial blood pressure (SABP) ⩾160 mmHg, documented at least twice, over several days." | 4.31 | Concurrent disorders of cats with diabetes mellitus and arterial systolic hypertension. ( Hess, RS; Williams, JG, 2023) |
"To study the development of microalbuminuria (MAU) in essential hypertension (EHT), we investigated the association of MAU with central blood pressure (CBP), direct renin concentration (DRC), plasma aldosterone (PA), and uric acid (UA)." | 4.31 | Central diastolic blood pressure, plasma aldosterone and uric acid are associated with microalbuminuria in essential hypertension: a case-control study. ( Chou, H; Li, J; Li, Y; Shi, L; Wei, M; Yang, N, 2023) |
"Activity of the circulating renin-angiotensin-aldosterone system (RAAS) has not been comprehensively characterized in cats with systemic hypertension (SH) or cardiomyopathy (CM), and the effects of furosemide or amlodipine treatment on the RAAS have not been fully evaluated in cats." | 4.12 | Circulating renin-angiotensin-aldosterone system activity in cats with systemic hypertension or cardiomyopathy. ( Domenig, O; Guillot, E; Mochel, JP; Ward, JL; Ware, WA; Yuan, L, 2022) |
"The saline suppression test (SST) and captopril challenge test (CCT) are commonly used confirmatory tests for primary aldosteronism (PA)." | 4.02 | Seated Saline Suppression Test Is Comparable With Captopril Challenge Test for the Diagnosis of Primary Aldosteronism: A Prospective Study. ( Cheng, Q; Du, Z; Feng, Z; He, W; Hu, J; Li, Q; Liu, B; Song, Y; Wang, Z; Xu, Z; Yang, J; Yang, S, 2021) |
"We prospectively enrolled 121 patients with confirmed primary aldosteronism who started mineralocorticoid receptor antagonist (canrenone) treatment." | 4.02 | Mineralocorticoid Receptor Antagonist Effect on Aldosterone to Renin Ratio in Patients With Primary Aldosteronism. ( Avataneo, V; Bertello, C; Buffolo, F; Burrello, J; D'Avolio, A; Mengozzi, G; Monticone, S; Mulatero, P; Pecori, A; Rabbia, F; Rumbolo, F; Veglio, F, 2021) |
"Recent reports described cases of severe hypertension and hypokalemia accompanied by low renin and aldosterone levels during antifungal therapy with posaconazole and itraconazole." | 3.96 | Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals. ( Beck, KR; Odermatt, A; Telisman, L; Thompson, GR; van Koppen, CJ, 2020) |
"Vascular function, including reactive hyperemia index (RHI), flow-mediated vasodilation (FMD) and nitroglycerine-induced vasodilation (NID), arterial stiffness including brachial-ankle pulse wave velocity (baPWV) and brachial intima-media thickness (IMT) and ROCK activity in peripheral leukocytes were measured before and after 12 weeks of treatment with eplerenone in 50 patients with IHA." | 3.91 | Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study. ( Aibara, Y; Chayama, K; Goto, C; Hashimoto, H; Higashi, Y; Kajikawa, M; Kihara, Y; Kishimoto, S; Liao, JK; Maruhashi, T; Matsui, S; Nakashima, A; Noma, K; Oki, K; Takaeko, Y; Yusoff, FM, 2019) |
" We report our long-term single-practice experience in 5 patients with chronic hyperaldosteronism (HA, including 3 with glucocorticoid remediable aldosteronism, GRA) treated with low-dose amiloride (a specific epithelial sodium channel [ENaC] blocker) 5-10 (mean 7) mg daily for 14-28 (mean 20) years." | 3.91 | Long-term BP control and vascular health in patients with hyperaldosteronism treated with low-dose, amiloride-based therapy. ( Hong, M; Hussain, T; Izzo, JL; Osmond, PJ, 2019) |
"The Captopril challenge test (CCT) is an easy-conduct confirmatory test for diagnosing primary aldosteronism (PA)." | 3.91 | The captopril challenge test for diagnosing primary Aldosteronism in a Chinese population. ( Feng, WH; Li, HY; Li, P; Zhang, WJ; Zhang, Y; Zhu, DL; Zhu, KY, 2019) |
" We report our long-term single-practice experience in an unusual group of five patients with chronic hyperaldosteronism (HA, including three with glucocorticoid-remediable aldosteronism, GRA) treated with low-dose amiloride (a specific epithelial sodium channel [ENaC] blocker) 5-10 (mean 7) mg daily for 14-28 (mean 20) years." | 3.91 | Maintenance of long-term blood pressure control and vascular health by low-dose amiloride-based therapy in hyperaldosteronism. ( Hong, M; Hussain, T; Izzo, JL; Osmond, PJ, 2019) |
"High salt intake markedly enhances hypertension induced by angiotensin II (Ang II)." | 3.88 | Central and peripheral slow-pressor mechanisms contributing to Angiotensin II-salt hypertension in rats. ( Ahmad, M; Blaustein, MP; Hamlyn, JM; Keshtkar-Jahromi, M; Leenen, FHH; Lu, J; Wang, HW, 2018) |
"In the PATHWAY-2 study of resistant hypertension, spironolactone reduced blood pressure substantially more than conventional antihypertensive drugs." | 3.88 | Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies. ( Brown, MJ; Caulfield, MJ; Cruickshank, JK; Ford, I; MacDonald, TM; Mackenzie, IS; McInnes, GT; Morant, SV; Padmanabhan, S; Salsbury, J; Sever, P; Webb, DJ; Williams, B, 2018) |
"Elevated circulating uric acid has been postulated to play an important pathophysiological role in estrogen-progestin combined oral contraceptive (COC)-induced hypertension and endothelial dysfunction." | 3.88 | Inhibition of adenosine deaminase and xanthine oxidase by valproic acid abates hepatic triglyceride accumulation independent of corticosteroids in female rats treated with estrogen-progestin. ( Areola, ED; Badmus, OO; Kim, I; Michael, OS; Olatunji, LA; Omolekulo, TE, 2018) |
" There are very little data about the effects of increased angiotensin II (Ang II) concentrations during pregnancy on in utero development of the fetus." | 3.85 | Prenatal exposure to angiotensin II increases blood pressure and decreases salt sensitivity in rats. ( Krskova, L; Okuliarova, M; Olexova, L; Panakova, Z; Senko, T; Svitok, P; Zeman, M, 2017) |
"These results demonstrates that hypertension and insulin resistance induced by COC is associated with increased cardiac RAS and PAI-1 gene expression, which is likely to be through corticosterone-dependent but not aldosterone-dependent mechanism." | 3.85 | Activation of cardiac renin-angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder. ( Kim, IK; Olatunji, LA; Seok, YM; Usman, TO, 2017) |
"Stroke-prone spontaneously hypertensive (SHRSP) rats were administered losartan, amlodipine or saline for 6 or 16weeks at the onset of prehypertension." | 3.85 | Early treatment with losartan effectively ameliorates hypertension and improves vascular remodeling and function in a prehypertensive rat model. ( He, DH; Lin, JX; Xie, Q; Xu, CS; Zhang, LM, 2017) |
"Activation of angiotensinergic pathways by central aldosterone (Aldo)-mineralocorticoid receptor (MR) pathway plays a critical role in angiotensin II (Ang II)-induced hypertension." | 3.83 | Mineralocorticoid and angiotensin II type 1 receptors in the subfornical organ mediate angiotensin II - induced hypothalamic reactive oxygen species and hypertension. ( Ahmad, M; Chen, A; Huang, BS; Leenen, FH; Wang, HW; White, RA, 2016) |
"Cross-sectional data of the single-center "Eplerenone in Primary Hyperparathyroidism" trial were used." | 3.83 | Parathyroid hormone, aldosterone-to-renin ratio and fibroblast growth factor-23 as determinants of nocturnal blood pressure in primary hyperparathyroidism: the eplerenone in primary hyperparathyroidism trial. ( Belyavskiy, E; Brandenburg, VM; Brussee, H; Catena, C; Fahrleitner-Pammer, A; Gaksch, M; Grübler, MR; März, W; Meinitzer, A; Perl, S; Pieske, B; Pilz, S; Scharnagl, H; Sechi, LA; Tomaschitz, A; Van Ballegooijen, AJ; Verheyen, N; Wetzel, J, 2016) |
"Among patients with essential hypertension, circulating endogenous ouabain and Aldo are typically coelevated and their BP is salt-sensitive." | 3.83 | Endogenous ouabain and aldosterone are coelevated in the circulation of patients with essential hypertension. ( Brioni, E; Casamassima, N; Hamlyn, JM; Lanzani, C; Manunta, P; Messaggio, E; Simonini, M; Tentori, S; Zagato, L, 2016) |
" Anthropometric parameters and aldosterone, plasma renin activity, cortisol, cortisone, Homeostasis Model Assessment Insulin Resistance (HOMA-IR), high-sensitivity C-reactive protein, adiponectin, IL-6, plasminogen activator inhibitor type 1 levels and matrix metalloproteinase-9 and matrix metalloproteinase-2 (MMP-9 and MMP-2) activities were measured." | 3.83 | Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension. ( Aglony, M; Allende, F; Bancalari, R; Baudrand, R; Campino, C; Carvajal, CA; Fardella, CE; Fuentes, CA; García, H; García, L; Kalergis, AM; Lagos, CF; Loureiro, C; Martinez-Aguayo, A; Sanhueza, S; Solari, S; Tapia-Castillo, A; Valdivia, C; Vecchiola, A, 2016) |
"Thirty-three consecutive patients with essential hypertension and hypovitaminosis D underwent therapy with cholecalciferol 50 000 IU/week orally for 8 weeks." | 3.83 | Cholecalciferol treatment downregulates renin-angiotensin system and improves endothelial function in essential hypertensive patients with hypovitaminosid D. ( Bacca, A; Bernini, G; Bruno, RM; Carrara, D; Duranti, E; Ghiadoni, L; Taddei, S, 2016) |
" In this study, we sought to determine if renal denervation (RDN) inhibits aldosterone expression and associated cardiovascular pathophysiological changes in angiotensin II (Ang II)-induced hypertension." | 3.83 | Renal denervation attenuates aldosterone expression and associated cardiovascular pathophysiology in angiotensin II-induced hypertension. ( Chen, DR; Chen, J; Gao, PJ; Hong, MN; Li, XD; Ma, Y; Ruan, CC; Wu, YJ; Xu, JZ; Zhu, DL, 2016) |
"The objective of this article is to measure serum dehydroepiandrosterone sulfate (DHEA-S) concentration in both genders with primary aldosteronism (PA)." | 3.81 | Serum dehydroepiandrosterone sulfate concentration is lower in women with primary aldosteronism. ( Chen, AH; Huang, TS; Li, HY; Lin, YH; Wu, VC, 2015) |
"Angiotensin II type 1 receptor blockade has neuroprotective effects in animal stroke models, but no effects in clinical stroke trials." | 3.81 | RAAS and stress markers in acute ischemic stroke: preliminary findings. ( Back, C; Edvinsson, L; Iversen, HK; Jensen, LT; Larsen, VA; Skovgaard, K; Thiesen, KL, 2015) |
"The renal mechanisms responsible for angiotensin II (ANG II)-induced hypertension remain incompletely understood." | 3.81 | Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension. ( Li, XC; Miguel-Qin, E; Shull, GE; Zhuo, JL, 2015) |
" This study suggests that telmisartan (TEL) can inhibit myocardial fibrosis of hypertensive left ventricular hypertrophy (LVH) through the transforming growth factor-β1 (TGF-β1)/Smad signaling pathway." | 3.80 | Telmisartan delays myocardial fibrosis in rats with hypertensive left ventricular hypertrophy by TGF-β1/Smad signal pathway. ( Guan, G; Ma, A; Shao, L; Tian, G; Wang, J; Wang, Y; Zhang, Y, 2014) |
" On day 11, hypertension was induced by continuous angiotensin II infusion." | 3.80 | M-atrial natriuretic peptide and nitroglycerin in a canine model of experimental acute hypertensive heart failure: differential actions of 2 cGMP activating therapeutics. ( Burnett, JC; Cataliotti, A; Chen, HH; Ichiki, T; McKie, PM; Sangaralingham, SJ, 2014) |
"Eplerenone is a highly selective aldosterone blocker, which has the potential to lower blood pressure (BP) in patients with hypertension." | 3.80 | The velocity of home blood pressure reduction in response to low-dose eplerenone combined with other antihypertensive drugs determined by exponential decay function analysis. ( Asayama, K; Elnagar, N; Hosaka, M; Imai, Y; Ishikura, K; Mano, N; Obara, T; Ohkubo, T; Satoh, M, 2014) |
" We investigated the effects of upregulating heme-oxygenase (HO) on myocardial histo-pathological lesions, proinflammatory cytokines/chemokines, oxidative mediators and important markers of heart failure such as osteopontin and osteoprotergerin in N(ω)-nitro-l-arginine methyl ester (L-NAME)-induced hypertension." | 3.80 | Heme oxygenase suppresses markers of heart failure and ameliorates cardiomyopathy in L-NAME-induced hypertension. ( Chibbar, R; Lane, N; Ndisang, JF, 2014) |
"In C57BL/6-mice, hypertension was induced by infusion of 600 ng/kg • min angiotensin II." | 3.80 | Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors. ( Amann, K; Brand, S; Mandel, P; Schupp, N; Zimnol, A, 2014) |
"Aim of the study is to evaluate the impact of spironolactone (SPL) on indexes of metabolic syndrome (MS) and further investigate the mechanisms underlying its protective effects." | 3.79 | Spironolactone prevents dietary-induced metabolic syndrome by inhibiting PI3-K/Akt and p38MAPK signaling pathways. ( Liang, LY; Lin, YE; Liu, MJ; Long, HD; Zeng, ZH, 2013) |
"This study was performed to determine the characteristics and mechanism of hypertension in SHR/NDmcr-cp(+/+) rats (SHRcp), a new model of metabolic syndrome, with a focus on the autonomic nervous system, aldosterone, and angiotensin II." | 3.79 | Novel mechanism for disrupted circadian blood pressure rhythm in a rat model of metabolic syndrome--the critical role of angiotensin II. ( Kataoka, K; Katayama, T; Kim-Mitsuyama, S; Koibuchi, N; Maeda, M; Matsui, K; Mingjie, M; Nakagawa, T; Ogawa, H; Sueta, D; Toyama, K; Uekawa, K; Waki, H; Yasuda, O, 2013) |
"Urinary 18-hydroxycortisol has been investigated as a marker of aldosterone-producing adenoma (APA)." | 3.79 | Quantification of urinary 18-hydroxycortisol using LC-MS/MS. ( Chiba, H; Fuda, H; Fujikawa, M; Hui, SP; Ikegawa, S; Jin, S; Kurosawa, T; Sakurai, T; Takahashi, Y; Takeda, S; Wada, N; Yanagisawa, K, 2013) |
"Circulating angiotensin II (Ang II) activates a central aldosterone-mineralocorticoid receptor neuromodulatory pathway, which mediates most of the Ang II-induced hypertension." | 3.79 | Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension. ( Ahmad, M; Huang, BS; Leenen, FH; White, RA, 2013) |
"Flos Chrysanthemi is used in a variety of diseases in traditional Chinese medicine including hypertension, and the total flavonoids (rich in luteolin (LUT) and buddleoside (BUD)) of Flos Chrysanthemi is known to modulate vascular functions and reduce the blood pressure." | 3.79 | Combined antihypertensive effect of luteolin and buddleoside enriched extracts in spontaneously hypertensive rats. ( Chen, SH; Gao, JL; Lei, J; Li, B; Lv, GY; Yu, JJ; Zhan, RJ; Zhang, YP; Zhang, ZR, 2013) |
"Leptin and aldosterone have been associated with the pathophysiological mechanisms of hypertension." | 3.79 | High-circulating leptin levels are associated with increased blood pressure in uncontrolled resistant hypertension. ( Barbaro, NR; de Faria, AP; de Haro Moraes, C; Demacq, C; Ferreira-Melo, SE; Figueiredo, VN; Júnior, HM; Martins, LC; Quinaglia, T; Sabbatini, AR, 2013) |
" We report a case of 55-year-old man with primary aldosteronism (PA) whose hyperaldosteronism was suppressed with the PPAR γ agonist pioglitazone." | 3.79 | Suppression of primary aldosteronism and resistant hypertension by the peroxisome proliferator-activated receptor gamma agonist pioglitazone. ( Harada, E; Kashiwagi, Y; Mizuno, Y; Morita, S; Shono, M; Yano, M; Yasue, H; Yoshimura, M, 2013) |
"In 205 patients with untreated essential hypertension, we measured components of the renin-angiotensin-aldosterone system, plasma levels of fibrinogen, D-dimer, prothrombin fragment 1 + 2 (F1 + 2), and plasminogen activator inhibitor-1 (PAI-1), and assessed cardiac characteristics with standard echocardiography." | 3.79 | Association of aldosterone with left ventricular mass in hypertension: interaction with plasma fibrinogen levels. ( Catena, C; Colussi, G; Sechi, LA; Valeri, M, 2013) |
" In the present study, we investigated the contribution of aldosterone to the renal p21 expression and senescence during the development of angiotensin II (AngII)-induced hypertension." | 3.78 | Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice. ( Deguchi, K; Hitomi, H; Kitada, K; Kobori, H; Lei, B; Masaki, T; Minamino, T; Mori, H; Nakano, D; Nishiyama, A, 2012) |
"5-T magnetic resonance imaging-arterial spin labeling in 34 subjects with arterial hypertension before aliskiren (pre-aliskiren), after 4 weeks of aliskiren treatment (300 mg), and 4-5 days (∼2." | 3.78 | Reversibility of the effects of aliskiren in the renal versus systemic circulation. ( Janka, R; Ott, C; Raff, U; Ritt, M; Schmieder, RE; Schneider, MP; Uder, M; Veelken, R; Ziegler, T, 2012) |
" Folic acid intake has beneficial effects upon the cardiovascular system decreasing hyperhomocysteinemia, however, more studies imply that it is related with other mechanisms." | 3.78 | The effects of ethanol upon hydric balance and arterial pressure in rats: folic acid as a possible hypotensor. ( Barrero, MJ; Carreras, O; Díaz Castro, J; Murillo, ML; Nogales, F; Ojeda, ML, 2012) |
"11β-hydroxysteroid dehydrogenase type 2 enzyme (11β-HSD2) inactivates cortisol (F) to cortisone (E); its impairment is associated with hypertension." | 3.78 | 11β-hydroxysteroid dehydrogenase type 2 polymorphisms and activity in a Chilean essential hypertensive and normotensive cohort. ( Baudrand, R; Campino, C; Carvajal, CA; Faccini, G; Fardella, CE; Guidi, G; Kalergis, AM; Lagos, CF; Morales, M; Olivieri, O; Owen, GI; Padilla, O; Pasini, F; Quinteros, H; Thichauer, J; Valdivia, C, 2012) |
"The aim of this paper is to report a case of unilateral PA with spontaneous remission and reduction of cardiac hypertrophy after long-term spironolactone (SP) therapy." | 3.78 | Unilateral primary aldosteronism with spontaneous remission after long-term spironolactone therapy. ( Demura, M; Karashima, S; Kometani, M; Takata, H; Takeda, Y; Yamagishi, M; Yoneda, T, 2012) |
"Idiopathic primary hyperaldosteronism (IHA) and low-renin essential hypertension (LREH) are common forms of hypertension, characterized by an elevated aldosterone-renin ratio and hypersensitivity to angiotensin II." | 3.78 | TASK-3 channel deletion in mice recapitulates low-renin essential hypertension. ( Barrett, PQ; Bayliss, DA; Carey, RM; Guagliardo, NA; Hu, C; Schertz, EM; Tyson, DA; Yao, J, 2012) |
"The finding of adipocyte-derived hormone leptin as an overstimulator of sympathetic activity brought a new perspective to the pathophysiological mechanisms of obesity-hypertension." | 3.78 | Leptin and aldosterone in sympathetic activity in resistant hypertension with or without type 2 diabetes. ( Boer-Martins, L; Demacq, C; Faria, AP; Figueiredo, VN; Martins, LC; Moraes, Cde H; Moreno, H, 2012) |
" Determination of metanephrines by high-pressure liquid chromatography has been well established for the diagnosis of pheochromocytomas, demonstrating high sensitivity and specificity." | 3.78 | Plasma and urinary metanephrines determined by an enzyme immunoassay, but not serum chromogranin A for the diagnosis of pheochromocytoma in patients with adrenal mass. ( Deutschbein, T; Hinrichs, J; Mann, K; Petersenn, S; Schmidt, H; Unger, N; Walz, MK, 2012) |
"To study on the difference of plasma renin activity (PRA), angiotensin II (Ang II), and aldosterone levels in patients with essential hypertension (EH) or primary aldosteronism (PA) or pheochromocytoma (PHEO), and to analyze the sensitivity and specificity on the diagnosis of PA among patients with hypertension with aldosterone/PRA ratio (ARR)." | 3.78 | [Differences of blood plasma renin activity, angiotensin II and aldosterone levels in essential or secondary hypertension]. ( Chen, S; Fu, CL; Li, M; Lu, L; Song, AL; Sun, ML; Tong, AL; Wang, YH; Zeng, ZP, 2012) |
"Many studies have implicated both angiotensin II (ANG II) and aldosterone (Aldo) in the pathogenesis of hypertension, the progression of renal injury, and cardiac remodeling after myocardial infarction." | 3.77 | Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension. ( Beltz, TG; Gomez-Sanchez, CE; Guo, F; Hay, M; Johnson, AK; Xue, B; Yu, Y, 2011) |
"Hypertension was induced by continuous angiotensin II (Ang II) infusion via osmotic mini-pumps over 4 weeks." | 3.77 | Effect of the plasminogen-plasmin system on hypertensive renal and cardiac damage. ( Cordasic, N; Daniel, C; Hartner, A; Heusinger-Ribeiro, J; Hilgers, KF; Klanke, B; Knier, B; Veelken, R, 2011) |
"Although the anorexic effects of leptin are lost in obesity, leptin-mediated sympatho-activation is preserved." | 3.77 | Impact of leptin-mediated sympatho-activation on cardiovascular function in obese mice. ( Belin de Chantemèle, EJ; Mintz, JD; Rainey, WE; Stepp, DW, 2011) |
" Since angiotensin II increases pendrin-mediated Cl(-) absorption in vitro, we asked whether angiotensin II increases pendrin expression in vivo and whether angiotensin-induced hypertension is pendrin dependent." | 3.77 | Angiotensin II acts through the angiotensin 1a receptor to upregulate pendrin. ( Agazatian, D; Bailey, JL; Coffman, TM; Farley, DB; Hong, S; Inagami, T; Kim, YH; Le, T; Matthews, SW; Pech, V; Verlander, JW; Wall, SM; Weiner, ID; Whitehill, FM, 2011) |
"Hypertension was induced in cyp1a1ren-2 transgenic rats by feeding indole-3-carbinol (n = 10) and in Fischer 344 rats by subcutaneously infusing ANG II (n = 7)." | 3.77 | Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome. ( Clemetson, KJ; Gebhard, S; Gesell-Salazar, M; Greinacher, A; Hammer, E; Kuttler, B; Peters, B; Peters, J; Rettig, R; Scharf, C; Steil, L; Völker, U, 2011) |
" In the present study, the effect of a subdose of fasudil, a selective ROCK inhibitor, on systemic hypertension and myocardium fibrosis induced by aldosterone was investigated in uninephrectomized Sprague-Dawley rats (SD)." | 3.77 | Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats. ( Guo, P; Masaki, T; Mori, H; Nishiyama, A; Wu, C, 2011) |
" It has been reported that eplerenone has a potential antihypertensive effect, with a profile slightly different from that of spironolactone, and has fewer adverse reactions, suggesting that it may become a first-line treatment for hypertension." | 3.76 | Clinical effects of eplerenone, a selective aldosterone blocker, in Japanese patients with essential hypertension. ( Fukuda, S; Sato, A, 2010) |
"Cilostazol (CILO), a selective inhibitor of phosphodiesterase 3 with potent antithrombotic property, has been shown to have a vasculoprotective effect in atherosclerosis animal models due to its potential anti-inflammatory and antioxidant actions." | 3.76 | Vasculoprotective effect of cilostazol in aldosterone-induced hypertensive rats. ( Hirata, Y; Hirono, Y; Sakurada, M; Sekizawa, N; Suzuki, N; Yoshimoto, T, 2010) |
"We evaluated the circulating levels of resistin, leptin, and adiponectin, echocardiographic left ventricle (LV) parameters, and the prevalence of metabolic syndrome (SM) in subjects with PA." | 3.76 | Adipokines and cardiometabolic profile in primary hyperaldosteronism. ( Cianci, R; Cotesta, D; De Toma, G; Iacobellis, G; Letizia, C; Pergolini, M; Petramala, L; Sciomer, S; Zinnamosca, L, 2010) |
"We, therefore compared, head-to-head, the aldosterone-renin ratio based on PRA with that based on DRA, at baseline and after captopril administration, for identifying aldosterone-producing adenoma (APA) in 251 patients of the Primary Aldosteronism Prevalence in hYpertension Study (PAPY)." | 3.76 | The aldosterone-renin ratio based on the plasma renin activity and the direct renin assay for diagnosing aldosterone-producing adenoma. ( Barisa, M; Belfiore, A; Desideri, G; Ferri, C; Letizia, C; Maccario, M; Mantero, F; Morganti, A; Palumbo, G; Patalano, A; Pessina, AC; Roman, E; Rossi, GP; Seccia, TM, 2010) |
" The current study was designed to advance our understanding of the therapeutic potential of M-ANP in a canine model of acute angiotensin II-induced hypertension with elevated cardiac filling pressures and aldosterone activation." | 3.76 | A novel atrial natriuretic peptide based therapeutic in experimental angiotensin II mediated acute hypertension. ( Boerrigter, G; Burnett, JC; Cataliotti, A; Chen, HH; Ichiki, T; Martin, FL; McKie, PM; Sangaralingham, SJ, 2010) |
"BC can inhibit left ventricular hypertrophy, plasma level of angiotensin II and aldosterone to some extent in SHR." | 3.76 | [Effects of Bai-Chuan capsule on left ventricular hypertrophy and correlative indexes]. ( Duan, HJ; He, LC; Zhan, YZ; Zhang, Y, 2010) |
"The present study was performed to characterize the autoregulatory efficiency of renal blood flow and glomerular filtration rate and the pressure-natriuresis relationship in transgenic rats with inducible angiotensin II (ANG II)-dependent hypertension (Cyp1a1-Ren-2 rats)." | 3.75 | Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats. ( Bürgelová, M; Cervenka, L; Erbanová, M; Husková, Z; Kramer, HJ; Mullins, JJ; Rakusan, D; Thumová, M; Vanecková, I; Vanourková, Z, 2009) |
"Genetic variation in the human angiotensinogen gene (AGT) influences plasma AGT concentration and susceptibility to essential hypertension by a mechanism that remains to be clarified." | 3.74 | Response to genetic manipulations of liver angiotensinogen in the physiological range. ( Cheng, T; Gociman, B; Hillas, E; Hunter, G; Hunter, J; Lalouel, JM; Lott, P; Monson, S; Rohrwasser, A; Ying, J, 2008) |
"Cortisol has been implicated in hypertension and lately reported to be regulated at the pre-receptor level by the 11betaHSD1 enzyme, which converts cortisone (E) to cortisol (F)." | 3.74 | [Possible pathogenetic role of 11 beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) gene polymorphisms in arterial hypertension]. ( Artigas, RA; Carvajal, CA; Fardella, CE; Morales, MA; Mosso, LM; Ortiz, E; Owen, GI, 2008) |
" To elucidate the potential role of local renin-angiotensin system in aldosterone-induced cardiovascular injury, we investigated the effects of selective mineralocorticoid receptor (MR) antagonist eplerenone (EPL), angiotensin (Ang) II type 1 receptor antagonist candesartan (ARB), and superoxide dismutase mimetic tempol (TEM) on the development of hypertension, vascular injury, oxidative stress, and inflammatory-related gene expression in aldosterone-treated hypertensive rats." | 3.74 | Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: the possible role of local renin-angiotensin system. ( Hirata, Y; Hirono, Y; Kobayashi, N; Sakurada, M; Shichiri, M; Sugiyama, T; Suzuki, N; Takai, S; Yoshimoto, T, 2007) |
" To elucidate its significance for myocardial fibrosis in the hypertensive heart, we used a mouse model with infusion of angiotensin II and examined results by histology, immunohistochemistry, in situ hybridization, and quantitative real-time reverse transcriptase polymerase chain reaction (RT-PCR)." | 3.74 | Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation. ( Hiroe, M; Imanaka-Yoshida, K; Inada, H; Nishioka, T; Onishi, K; Suzuki, M; Takakura, N; Yoshida, T, 2007) |
" We investigated its role in angiotensin II-induced hypertension in the Tsukuba hypertensive mouse (THM)." | 3.74 | Absence of peroxisome proliferator-activated receptor-alpha abolishes hypertension and attenuates atherosclerosis in the Tsukuba hypertensive mouse. ( Bak, S; Coleman, T; Osher, E; Semenkovich, CF; Stern, N; Tordjman, KM; Vechoropoulos, M; Yudovich, R, 2007) |
"Renin-angiotensin system gene polymorphisms are associated with essential hypertension; angiotensinogen gene variants are considered potential genetic risk factors." | 3.74 | Significance of angiotensinogen gene haplotypes and genotypes combinations in hypertension. ( Goyal, AK; Gupta, M; Javed, S; Kumar, R; Nejatizadeh, A; Pasha, MQ; Stobdan, T, 2008) |
"We correlated the BP response to spironolactone 50 mg/day to baseline ARR in 69 hypertensive patients (mean [+/-SD] age 57 +/- 2 years, 65% male), consisting of 39 subjects with long-standing hypertension (4." | 3.73 | Does aldosterone-to-renin ratio predict the antihypertensive effect of the aldosterone antagonist spironolactone? ( Feely, J; Hall, M; Mahgoub, M; Mahmud, A, 2005) |
"To compare efficacy of use of the blocker of aldosteron receptors spironolactone and diuretic indapamide in low-renin arterial hypertension (AH), their action on blood pressure, serum concentrations of sodium, potassium, creatinine, plasmic renin activity (PRA), plasmic aldosteron concentration (PAC)." | 3.73 | [Use of spironolactone and indapamide in the treatment of low-renin arterial hypertension]. ( Bagdonas, G; Kazanavichus, G; Naudzhunas, A; Yankauskene, L, 2006) |
" Since chronic inhibition of nitric oxide (NO) synthase with N(omega)-nitro-L-arginine methyl ester (L-NAME) induces systemic hypertension associated with cardiovascular inflammation and remodeling, we examined the potential role of aldosterone in this process using eplerenone, a selective aldosterone receptor antagonist." | 3.73 | The antagonism of aldosterone receptor prevents the development of hypertensive heart failure induced by chronic inhibition of nitric oxide synthesis in rats. ( Asano, Y; Fujita, M; Hirata, A; Hori, M; Kitakaze, M; Minamino, T; Okada, K; Sanada, S; Shintani, Y; Takashima, S; Tomoike, H; Tsukamoto, O; Yamasaki, S; Yulin, L, 2006) |
"To investigate the association of aldosterone synthase (CYP11B2) -344T/C polymorphism with plasma renin activity (PRA), and concentrations of angiotensin II (Ang II) and aldosterone (Aldo) in patients with essential hypertension (EH)." | 3.73 | [Association of aldosterone synthase gene -344T/C polymorphism with plasma aldosterone and angiotensin II concentration in hypertensive patients]. ( Chu, SL; Gao, PJ; Hu, BC; Wang, GL; Wang, JG; Wang, ZH; Zhu, DL, 2006) |
"A unique model of hypertension developed in our laboratory shows that neonatal degeneration of capsaicin-sensitive sensory nerves renders a rat responsive to salt load with a significant rise in blood pressure." | 3.72 | Increased salt sensitivity induced by impairment of sensory nerves: is nephropathy the cause? ( Wang, DH; Zhao, Y, 2003) |
"Losartan attenuates BSO-induced hypertension, which appears to be mediated, in part, by angiotensin II and the prostanoid endothelium-derived factors." | 3.72 | Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats. ( Abukhalaf, IK; Bayorh, MA; Eatman, D; Ganafa, AA; Silvestrov, N; Socci, RR, 2003) |
"The effects of low-dose oral spironolactone (SPIRO) in a rat model of hypertensive heart failure (spontaneously hypertensive heart failure rat) were compared with its effects when combined with captopril (CAP)." | 3.72 | Combined effects of low-dose oral spironolactone and captopril therapy in a rat model of spontaneous hypertension and heart failure. ( Bauer, JA; Ghosh, S; Holycross, BJ; Kambara, A; Kwiatkowski, P; McCune, SA; Schanbacher, B; Wung, P, 2003) |
"We investigated the pathophysiological role of the cardiac adrenomedullin (AM) system, including the ligand, receptor and amidating activity in the hypertrophied heart in severe hypertension." | 3.72 | Upregulation of ligand, receptor system, and amidating activity of adrenomedullin in left ventricular hypertrophy of severely hypertensive rats: effects of angiotensin-converting enzyme inhibitors and diuretic. ( Akimoto, K; Minamino, N; Mori, Y; Nishikimi, T; Tadokoro, K; Wang, X, 2003) |
" This study investigated whether cyclooxygenase-2 expression is regulated in the kidney, in an angiotensin II- and aldosterone-induced hypertension model." | 3.72 | Analysis of angiotensin II mediated COX-2 downregulation in angiotensin II- or aldosterone-infused hypertensive rat. ( Lee, YJ; Lim, WC; Park, JB, 2003) |
"When performed with careful regard to confounding factors, measurement of the aldosterone : renin ratio in all hypertensive individuals, followed by fludrocortisone suppression testing to confirm or exclude primary aldosteronism and adrenal venous sampling to determine the subtype, can result in the detection of significant numbers of patients with specifically treatable or potentially curable hypertension." | 3.72 | High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients. ( Archibald, C; Cowley, DC; Gordon, RD; Gunasekera, TG; Smithers, BM; Stowasser, M; Ward, G, 2003) |
"In Lyon hypertensive (LH) rats, a model of low-renin genetic hypertension, we investigated adrenal sensitivity to angiotensin II in terms of angiotensin II receptor (AT1 and AT2 receptors) regulation, morphological changes, and aldosterone and corticosterone secretion." | 3.72 | Hypersensitivity of the adrenal cortex to trophic and secretory effects of angiotensin II in Lyon genetically-hypertensive rats. ( Aguilar, F; Claustrat, B; Li, JY; Lo, M; Saez, JM; Sassard, J, 2004) |
"Functional changes in the kidneys of healthy men with (FH+) (n = 15) and without (FH-) (n = 15) family history of primary arterial hypertension were examined during administration of low-dose exogenous angiotensin II (A2) (1 ng/kg per min) before and after acute (1 mg intravenous enalaprilat) and chronic (7 days oral enalapril, 30 mg/day) angiotensin-converting enzyme (ACE) inhibition." | 3.72 | Increased renovascular response to angiotensin II in persons genetically predisposed to arterial hypertension disappears after chronic angiotensin-converting enzyme inhibition. ( Bock, A; Dieterle, T; Drewe, J; Gyr, K; Haberthür, C; Huber, PR; Martina, B; Schächinger, H, 2004) |
"There are not studies about the utility of modified liberation doxazosin (MLD) in the combined treatment of the true resistant hypertension (TRH)." | 3.72 | [Effect of modified liberation doxazosin on blood pressure, insulin resistance, and catecholamine secretion in patients with true resistant hypertension]. ( Aliaga Martínez, L; Fernández-Torres, C; Jiménez-Alonso, J; Mediavilla García, JD; Sabio, JM, 2004) |
"The dual ACE+NEP inhibitor MDL prevented and regressed severe hypertension and cardiovascular damage, even in this model of severe angiotensin II-dependent hypertension with pronounced cardiovascular damage." | 3.71 | Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor. ( Agabiti-Rosei, E; Bova, S; Cavallin, M; Mazzocchi, G; Nussdorfer, GG; Pessina, AC; Rizzoni, D; Rossi, GP, 2002) |
"Aldosterone-induced hypertension is associated with renal damage that may be mediated by endothelin-1 (ET-1)." | 3.71 | Contribution of endothelin-1 to renal activator protein-1 activation and macrophage infiltration in aldosterone-induced hypertension. ( Chen, X; He, G; Schiffrin, EL; Tostes, RC; Touyz, RM, 2002) |
"In 43 untreated patients with hypertension with electrocardiographic left ventricular hypertrophy, we measured relative wall thickness and left ventricular mass index by echocardiography and by magnetic resonance imaging (n = 32), intima-media cross-sectional area, and distensibility of the common carotid arteries by ultrasound, media/lumen ratio of isolated subcutaneous resistance arteries by myography, and median 24-hour systolic BP (n = 40), serum insulin, and plasma levels of epinephrine, norepinephrine, renin, angiotensin II, aldosterone, and endothelin." | 3.71 | Is cardiovascular remodeling in patients with essential hypertension related to more than high blood pressure? A LIFE substudy. Losartan Intervention For Endpoint-Reduction in Hypertension. ( Devereux, RB; Dige-Petersen, H; Frandsen, E; Hermann, KL; Ibsen, H; Olsen, MH; Rokkedal, J; Wachtell, K, 2002) |
"The aim of the study was to compare hypotensive reaction after treatment with enalapril and enalapril with isosorbide mononitrate in patients with mild and moderate hypertension." | 3.71 | [Effect of isosorbide mononitrate on hypotensive action of enalapril in patients with mild and moderate hypertension]. ( Przewłocka-Kosmala, M, 2002) |
"The renin-angiotensin-aldosterone system plays a major role in the pathogenesis of hypertension by enhancing the production or the activity of angiotensin II (ANG II)." | 3.71 | Hormone replacement therapy increases plasma level of angiotensin II in postmenopausal hypertensive women. ( Ichikawa, S; Kanda, T; Kobayashi, I; Sumino, H; Umeda, M, 2001) |
"Increased endothelin-1 may be associated with elevation of blood pressure (BP) and promotion of vascular hypertrophy, especially in salt-sensitive hypertension." | 3.71 | ET(A) receptor antagonist prevents blood pressure elevation and vascular remodeling in aldosterone-infused rats. ( Park, JB; Schiffrin, EL, 2001) |
"An increased sensitivity to angiotensin II (Ang II) has been observed in patients with established hypertension." | 3.71 | Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension. ( Delles, C; Jacobi, J; Klingbeil, AU; Schlaich, MP; Schmidt, BM; Schmieder, RE; Schneider, MP, 2002) |
"(1) Salt sensitive hypertension, which occurs as a result of treatment with nitric oxide synthase inhibitors, is associated with a loss of the usual down-regulatory effect of dietary sodium on angiotensin II (Ang II) synthesis." | 3.71 | Dysregulation of angiotensin II synthesis is associated with salt sensitivity in the spontaneous hypertensive rat. ( Duggan, KA; Hodge, G; Ye, VZ, 2002) |
"Spironolactone is a safe, effective therapy for patients with refractory hypertension." | 3.71 | The role of spironolactone in the treatment of patients with refractory hypertension. ( Carré, E; Lincoff, AM; Mertes, M; Ouzan, J; Pérault, C, 2002) |
"In a previous study, we showed that dietary gamma-linolenic acid (GLA), an omega-6 polyunsaturated fatty acid found in borage oil (BOR), attenuates the development of hypertension in young spontaneously hypertensive rats (SHR)." | 3.70 | Effects of dietary gamma-linolenic acid on blood pressure and adrenal angiotensin receptors in hypertensive rats. ( Ball, DL; Engler, MB; Engler, MM; Goodfriend, TL; Schambelan, M, 1998) |
"The angiotensinogen gene has recently been linked to essential hypertension." | 3.70 | T235 variant of the angiotensinogen gene and blood pressure in the Chilean population. ( Claverie, X; Fardella, CE; Montero, J; Vignolo, P; Villarroel, L, 1998) |
"In 30 normotensive individuals and 30 subjects with mild essential hypertension (white men, mean age 26+/-3 years), the responsiveness to angiotensin II was assessed by measuring changes in mean arterial pressure, renal blood flow, glomerular filtration rate and aldosterone secretion in response to i." | 3.70 | Hyper-responsiveness to angiotensin II is related to cardiac structural adaptation in hypertensive subjects. ( Hilgers, K; Klingbeil, AU; Langenfeld, MR; Schäufele, T; Schmieder, RE; Schobel, H, 1999) |
" The antistroke effects of captopril treatment occurred without an antihypertensive effect, weren't altered by enhancing hypertension during treatment (with dexamethasone), and couldn't be duplicated by antihypertensive treatment with hydralazine." | 3.70 | Effect of poststroke captopril treatment on mortality associated with hemorrhagic stroke in stroke-prone rats. ( King, SR; Smeda, J; Vasdev, S, 1999) |
" Five of these patients with aldosterone producing adenoma were operated on and four patients with idiopathic hyperaldosteronism were treated with spironolactone." | 3.70 | Insulin action in primary hyperaldosteronism before and after surgical or pharmacological treatment. ( Haas, T; Hilgertová, J; Prázný, M; Sindelka, G; Skrha, J; Widimský, J, 2000) |
"Clinical evaluation of hypotensive effectiveness and the cardiovascular and side effects of enalapril monotherapy of significant essential hypertension (SEH) in adolescents was performed." | 3.69 | [Evaluation of the efficacy and safety of monotherapy for significant essential hypertension in adolescents with use of enalapril]. ( Cichocka, E; Januszewicz, P; Kawalec, W; Wyszyńska, T, 1995) |
"Flosequinan (BTS 49465, 7-fluoro-1-methyl-3-methyl-sulphinyl-4-quinolone), a recently direct-acting vasodilator that should cause relatively less reflex tachycardia, was given in a single oral dose of 200 mg to 10 untreated patients with moderate to severe hypertension." | 3.69 | Acute effects of flosequinan (BTS 49465) in untreated moderate to severe hypertension. ( Janssen, MC; Reyenga, J; Smits, P; Thien, T, 1995) |
"The transgenic TGR(mRen-2)27 rat, in which the Ren-2 mouse renin gene is transfected into the genome of the Sprague-Dawley rat, develops severe hypertension at a young age that responds to inhibitors of angiotensin-converting enzyme and to antagonists of the type 1 angiotensin II (Ang II) receptor." | 3.69 | Angiotensin and bradykinin peptides in the TGR(mRen-2)27 rat. ( Campbell, DJ; Ganten, D; Kladis, A; Rees, B; Rong, P; Skinner, SL, 1995) |
"The nonmodulating trait thought to explain development of hypertension in 25 to 35% of patients, is characterized by abnormal angiotensin II (AII)-mediated control of aldosterone release and renal blood flow (RBF)." | 3.69 | Nonmodulating trait may precede the development of hypertension. ( Gordon, MB; Gordon, MS; Hollenberg, NK; Williams, GH, 1994) |
"In twelve hypertensive patients with end-stage renal disease (ESRD) due to chronic glomerulonephritis (CGN), the mechanisms of renin and aldosterone regulation were studied by exogenously infused angiotensin II, captopril, and upright posture." | 3.69 | The impaired control of plasma renin activity in hypertensive patients with end-stage renal disease due to chronic glomerulonephritis. ( Ishii, M; Nagasawa, T; Shionoiri, H; Umemura, S; Yasuda, G, 1994) |
"Ten cases of adrenal adenomas, one case with unilateral adrenal hyperplasia, and another case with apparent bilateral are reported, in whom an alternative pathway of aldosterone via 21-deoxyaldosterone is operative." | 3.69 | A new subset of mineralocorticoid hypertension with excess of 21-deoxyaldosterone and Kelly's-M1 steroid: clinical and morphological findings. ( Abdelhamid, S; Bönhof, JA; Haack, D; Lewicka, S; Müller-Lobeck, H; Nensel, U; Pahl, S; Remberger, K; Röckel, A; Vecsei, P, 1995) |
"The T235 allele of the angiotensinogen gene (AGT) has been associated with hypertension." | 3.69 | The serum angiotensinogen concentration and variants of the angiotensinogen gene in white and black children. ( Bloem, LJ; Manatunga, AK; Pratt, JH; Tewksbury, DA, 1995) |
"We examined plasma renin activity (PRA), plasma aldosterone (PA), atrial natriuretic factor (ANF) and endogenous digitalis-like factor (DLF) in 15 healthy subjects and 15 patients with essential hypertension (EH) to obtain basal values and values after extracellular fluid volume (ECFV) expansion caused by infusion of isotonic saline solution over a period of 2 hours (20 mg/kg)." | 3.69 | The role of endogenous digitalis-like factor in blood pressure regulation in essential hypertension. ( Lichardus, B; Machánová, Y; Murár, J; Pjescák, M; Rosochová, I; Suchmanová-Lazúrová, I; Trejbal, D, 1994) |
" To define possible cellular mechanisms involved in central mineralocorticoid action, benzamil, an amiloride analogue with selective affinity for the Na+ channel, was continuously infused intracerebroventricularly in three mineralocorticoid-dependent hypertension models in Sprague-Dawley rats, the continuous subcutaneous infusion of aldosterone, the intracerebroventricular infusion of aldosterone, and the ingestion of carbenoxolone, a synthetic licorice analogue." | 3.69 | Effect of central amiloride infusion on mineralocorticoid hypertension. ( Gomez-Sanchez, CE; Gomez-Sanchez, EP, 1994) |
"To investigate the possible role of dopamine, a catecholamine with natriuretic properties, in modulating the escape from the sodium-retaining effects of mineralocorticoids, we submitted six aldosterone-producing adenoma (APA) patients and six low-renin essential hypertensive patients to acute volume expansion by head-out water immersion with or without dopaminergic blockade by metoclopramide." | 3.69 | Escape from the sodium-retaining effects of mineralocorticoids: is there a role for dopamine? ( Coruzzi, P, 1994) |
"11 beta-Hydroxysteroid dehydrogenase (11 beta-HSD) activity in mesenteric arteries of 4-week- and 8-week-old Dahl rats was determined to evaluate the relationship between glucocorticoids and norepinephrine in hypertension, 11 beta-HSD activity (expressed as the percentage conversion of 3H-corticosterone (B) to 3H-11-dehydrocorticosterone (A)) significantly decreased in 8-week-old Dahl salt-sensitive (DS) rats (11." | 3.69 | Decreased activity of 11 beta-hydroxysteroid dehydrogenase in mesenteric arteries of Dahl salt-sensitive rats. ( Hatakeyama, H; Iki, K; Miyamori, I; Takeda, R; Takeda, Y; Yoneda, T, 1994) |
" Study 1: A long-term (4 weeks) treatment with slow-release nifedipine (Nif), 40-60 mg/day, was performed in 9 in-patients with essential hypertension (EHT)." | 3.69 | [Mechanism of inhibition of aldosterone secretion by a Ca2+ channel blocker in patients with essential hypertension and patients with primary aldosteronism]. ( Iimura, O; Shimamoto, K; Yokoyama, T, 1995) |
"Approximately half of Caucasian patients with essential hypertension and with hyperaldosteronism exhibit elevated circulating levels of endogenous ouabain." | 3.69 | Immunoreactive endogenous ouabain in primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels. ( De Toni, R; Hamlyn, JM; Manunta, P; Pavan, E; Pessina, AC; Rossi, G; Semplicini, A, 1995) |
"The present study aimed to assess the influence of a highly industrialized environment on the prevalence of arterial hypertension and plasma levels of cholesterol, uric acid, aldosterone and plasma renin activity." | 3.69 | Does industrial environment influence the prevalence of arterial hypertension, plasma cholesterol and uric acid concentration and activity of the renin-aldosterone system? ( Kokot, F; Wiecek, A, 1996) |
" A patient with severe hypertension was found to have mildly impaired 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD) activity on the basis of urinary steroid metabolite ratios, low plasma aldosterone, angiotensin II and renin levels and marginally low levels of plasma potassium." | 3.69 | Sodium status, corticosteroid metabolism and blood pressure in normal human subjects and in a patient with abnormal salt appetite. ( Collier, A; Connell, JM; Fraser, R; Ingram, MC; Wallace, AM, 1996) |
" Urinary excretion rates of calcium, sodium, chloride, potassium, urinary calcium/creatinine index, the fractional excretion of sodium, potassium and uric acid, the creatinine clearance and serum values of creatinine, urea, uric acid, electrolytes, total proteins, parathormone (intact molecule), plasma renin activity, aldosterone, glucose, and insulin (fasting and after an oral glucose load) were performed in every patient and control subject." | 3.69 | Urinary calcium excretion in treated and untreated essential hypertension. ( Navarro-Antolin, J; Orte, L; Ortuño, J; Quereda, C; Sabater, J; Villafruela, JJ, 1996) |
"Nifedipine is a commonly used agent in treating hypertension and angina because of its vasodilator properties." | 3.69 | Effects of nifedipine treatment on the renin-angiotensin-aldosterone axis. ( Cunningham, SK; Fiad, TM; Hayes, FJ; McKenna, TJ, 1997) |
" Tsukuba hypertensive mice (THM) carry both human renin and angiotensinogen genes, and develop hypertension." | 3.69 | Development of polyuria in Tsukuba hypertensive mice carrying human renin and angiotensinogen genes. ( Fukamizu, A; Ikemoto, F; Mino, N; Murakami, K; Nishikibe, M; Tsuchida, M; Uehara, S, 1995) |
" We measured the urinary excretion of 19-noraldosterone in the spontaneously hypertensive rat (SHR) and stroke-prone SHR (SHRSP) during the development of hypertension and compared these measurements with Wistar-Kyoto (WKY) rats." | 3.69 | Urinary excretion of 19-noraldosterone in the spontaneously hypertensive rat and stroke-prone spontaneously hypertensive rat. ( Hurukawa, K; Inaba, S; Ito, Y; Miyamori, I; Takeda, R; Takeda, Y; Yoneda, T, 1995) |
"The angiotensinogen gene is one of the very few related by linkage analysis to human hypertension, but the linkage has been consistently shown only among males." | 3.69 | Age, gender, and non-modulation. A sexual dimorphism in essential hypertension. ( Bellini, C; Ferri, C; Fisher, ND; Gleason, R; Hollenberg, NK; Santucci, A; Seely, EW; Williams, GH, 1997) |
" Infusion of ebelactone B, (a selective inhibitor of carboxypeptidase Y-like exopeptidase, a kininase in rat urine), to normal BN-Ki rats during induction of hypertension with DOCA and salt, resulted in the reduction of the raised blood pressure, indicating that a site of action of kinins was at the luminal membrane of the renal tubule cells." | 3.69 | Role of the renal kallikrein-kinin system in the development of hypertension. ( Katori, M; Majima, M, 1997) |
"Myocardial fibrosis, associated with increased expression of angiotensin converting enzyme (ACE) and bradykinin (BK) receptor binding at sites of tissue repair, accompanies chronic elevations in circulating angiotensin II (AngII) and/or aldosterone (ALDO) that simulate chronic cardiac failure." | 3.69 | Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion. ( Ramires, FJ; Sun, Y; Weber, KT, 1997) |
"Elevations in plasma aldosterone enhance stroke development within captopril-treated SHRSP through mechanisms that do not involve stimulation of mineralocorticoid receptors or the enhancement of hypertension." | 3.69 | The role of blood pressure and aldosterone in the production of hemorrhagic stroke in captopril-treated hypertensive rats. ( MacLeod, AB; Smeda, JS; Vasdev, S, 1997) |
"We have investigated the possible involvement of endogenous corticosteroids in the maintenance of hypertension in aged lean and obese Zucker rats using the type II corticosteroid antagonist mifepristone." | 3.69 | Effects of the glucocorticoid II receptor antagonist mifepristone on hypertension in the obese Zucker rat. ( Clapham, JC; Turner, NC, 1997) |
"A 49-year-old man with liver cirrhosis and hypertension was found to have hyperkalemia out of a degree of renal insufficiency and metabolic acidosis with low to normal anion gap, aggravated by volume contraction with diarrhea and medications (captopril, spironolactone and atenolol) interfering with potassium homeostasis." | 3.68 | Hyperkalemia due to hyporeninemic hypoaldosteronism with liver cirrhosis and hypertension. ( Ahn, YH; Chang, DK; Choi, JW; Kee, CS; Kim, HJ, 1993) |
" Failure to suppress aldosterone with fludrocortisone acetate administration and oral salt loading confirmed the presence of primary aldosteronism in all six patients." | 3.68 | Evidence that primary aldosteronism may not be uncommon: 12% incidence among antihypertensive drug trial volunteers. ( Gordon, RD; Klemm, SA; Stowasser, M; Tunny, TJ; Ziesak, MD, 1993) |
"The present study was designed to investigate the effect of L-arginine administration on patients with essential and secondary hypertension by measuring haemodynamic parameters, neuroendocrine hormones and indicators of nitric oxide (NO) release." | 3.68 | Role of L-arginine-nitric oxide pathway in hypertension. ( Hishikawa, K; Kato, R; Nakaki, T; Saruta, T; Suzuki, H, 1993) |
"Clinical studies were performed on patients with mild-to-moderate essential hypertension to elucidate the efficacy and mode of action of manidipine." | 3.68 | Efficacy and mode of action of manidipine: a new calcium antagonist. ( Iimura, O; Shimamoto, K, 1993) |
"Vascular permeability of the coronary and mesenteric circulation is increased in association with the arterial hypertension that accompanies either endogenous activation of the renin-angiotensin-aldosterone system (RAAS) or exogenous administration of angiotensin II (AII)." | 3.68 | Coronary microvascular fluid flux and permeability: influence of angiotensin II, aldosterone, and acute arterial hypertension. ( Campbell, SE; Janicki, JS; Reddy, HK; Weber, KT; Zhou, G, 1993) |
"To evaluate the atrial natriuretic peptide response to angiotensin II (Ang II) infusion in non-modulating hypertension, we studied 31 men with essential hypertension." | 3.68 | Atrial natriuretic peptide in non-modulating essential hypertension. ( Balsano, F; Ferri, C; Luparini, RL; Santucci, A, 1993) |
"A case of primary aldosteronism treated with spironolactone therapy has been followed up for 24 years." | 3.68 | Twenty-four year spironolactone therapy in an aged patient with aldosterone-producing adenoma. ( Hashimoto, T; Ito, Y; Koshida, H; Miyamori, I; Morimoto, S; Morise, T; Takeda, R; Yamazaki, T, 1992) |
"To examine the role of mineralocorticoids in the pathophysiology of pregnancy-induced hypertension (PIH), we studied plasma aldosterone and 18-hydroxycorticosterone levels in 25 women with PIH and 25 normal pregnant women, as controls." | 3.68 | Mineralocorticoids and mineralocorticoid receptors in mononuclear leukocytes in patients with pregnancy-induced hypertension. ( Bastert, G; Bauer, H; E-Mistry, N; Stolz, W; Vecsei, P; Wacker, J, 1992) |
"The effect of manidipine on cardiac hypertrophy, coronary circulation, left ventricular weight and maximal coronary flow in hypertension was measured in DOCA/salt treated systolic hypertensive rats with and without manidipine treatment." | 3.68 | Effect of manidipine on cardiac hypertrophy and coronary circulation in DOCA/salt hypertensive rats. ( Asayama, J; Itoh, H; Kuwabara, T; Nakagawa, M; Nakata, T; Sasaki, S; Takeda, K; Takesako, T; Tanabe, S; Yamahara, Y, 1992) |
"The effect of treatment of hypertension with nifedipine on plasma renin activity, blood serum level of aldosterone in the course of renin test, and cortisol and growth hormone concentrations after stimulation with insulin hypoglycemia was followed during two weeks of treatment in 40 patients with essential hypertension." | 3.68 | [Effect of nifedipine treatment on the renin-aldosterone system and secretion of cortisol and growth hormone in patients with essential hypertension]. ( Kokot, F; Wnuk, R, 1991) |
"To clarify the hemodynamic and endocrine mechanisms of the hypotensive effect of amosulalol, an alpha- and beta-adrenoceptor antagonist, 19 patients with essential hypertension received amosulalol (20-80 mg/day; average 48." | 3.68 | Hemodynamic and endocrine changes associated with hypotensive action of amosulalol in essential hypertension. ( Ando, K; Fujita, T; Noda, H; Ogata, E, 1992) |
"Aim of this study was to assess the relationship between plasma concentration of atrial natriuretic factor (ANF) and its two-dimensional echocardiographic (left ventricular mass, left atrium diameter) and humoral (plasma renin and aldosterone) variables in essential hypertension (EH)." | 3.68 | Atrial natriuretic factor in essential hypertension: echocardiographic and humoral correlates. ( Favilla, S; Lattanzi, F; Lucarini, AR; Marini, C; Salvetti, A; Urbani, MP, 1992) |
"This study was conducted to elucidate renal uric acid metabolism in patients with primary aldosteronism (PA;16 cases) as compared with normotensive subjects (NT;25 cases) and essential hypertensives (EHT;51 cases)." | 3.68 | [Study on uric acid metabolism in patients with primary aldosteronism]. ( Iimura, O; Kikuchi, K; Komura, H; Marusaki, S; Namba, M; Ohtomo, T; Satoh, N; Suzuki, S; Takada, T, 1992) |
"Urinary excretion of 18-hydroxycortisol (18-OHF), 18-hydroxycorticosterone (18-OHB) and aldosterone 18-glucuronide (Aldo-18-glu) was measured in 10 patients with primary aldosteronism; 5 with aldosterone-producing adenoma (APA) and 5 with idiopathic hyperaldosteronism (IHA), 10 patients with essential hypertension (EHT) and 11 normotensive subjects." | 3.68 | Determination of urinary 18-hydroxycortisol in the diagnosis of primary aldosteronism. ( Iki, K; Itoh, Y; Miyamori, I; Takasaki, H; Takeda, R; Takeda, Y, 1992) |
"Plasma concentrations of renin and aldosterone were measured before and 60 min after taking 25 mg captopril in 242 patients with arterial hypertension (124 men, 118 women, aged 51." | 3.68 | [Does the captopril test improve the diagnosis of primary hyperaldosteronism?]. ( Bönner, G; Degenhardt, S; Grimm, U; Krone, W; Stimpel, M; Wambach, G, 1992) |
" In 10 patients with essential hypertension, we investigated the influence of betaxolol, a selective beta 1-adrenergic blocking agent, on renal function and on plasma levels of ANP during exercise, volume depletion and volume expansion." | 3.68 | Influence of betaxolol on renal function and atrial natriuretic peptide in essential hypertension. ( Grabensee, B; Heering, P; Hollenbeck, M; Kutkuhn, B; Plum, J, 1991) |
" Even though the angiotensin converting enzyme inhibitor captopril was previously found to attenuate this interstitial and perivascular fibrosis, the relative importance of arterial and ventricular systolic pressures versus circulating angiotensin II (AII) and aldosterone (AL) in promoting hypertrophy and collagen accumulation in renovascular hypertension is uncertain." | 3.68 | Remodeling of the rat right and left ventricles in experimental hypertension. ( Brilla, CG; Janicki, JS; Pick, R; Tan, LB; Weber, KT, 1990) |
"Plasma levels of atrial natriuretic factor were measured in 71 patients with essential hypertension and 13 with borderline arterial hypertension by using radioimmunoassay." | 3.68 | [Atrial natriuretic factor in patients with hypertension]. ( Bil'chenko, AV; Vasil'ev, IuM, 1991) |
"130 cases of patients with essential hypertension (EH) and 70 cases of normal subjects were researched for correlation between TCM differential types and plasma levels of renin, angiotension II, aldosterone, atrial natriuretic factor (ANF) in patients with EH." | 3.68 | [Relation between traditional Chinese medicine differential types and plasma levels of renin, angiotension II, aldosterone, atrial natriuretic factor in patients with essential hypertension]. ( Li, H, 1991) |
"Plasma levels of atrial natriuretic peptide (ANP) were measured in patients with normal renin essential hypertension (n = 12), low renin essential hypertension (n = 11) and primary aldosteronism due to aldosterone producing adenoma (APA, n = 8) and idiopathic hyperaldosteronism (IHA, n = 3) after overnight rest in the supine position and after 4 h upright posture and furosemide administration." | 3.68 | Dissociation of plasma atrial natriuretic peptide responses to upright posture and furosemide administration in patients with normal-, low renin essential hypertension and primary aldosteronism. ( Fütö, L; Gláz, E; Gutkowska, J; Kiss, R; Rácz, K; Sergev, O; Varga, I, 1991) |
"To study the effects of a novel angiotensin I converting enzyme inhibitor (ACEI) on hypertension-induced cardiac hypertrophy, benazepril hydrochloride (CGS 14824 A, CAS 86541-74-4) at the dose of 3 and 10 mg/kg/d p." | 3.68 | Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneously hypertensive rats. ( Hasegawa, Y; Inukai, T; Katahira, J; Nakao, K; Takemori, E, 1991) |
"0% by weight) of the neutral amino acid, L-tryptophan, on the development of hypertension during chronic exposure to cold." | 3.68 | Effect of chronic dietary treatment with L-tryptophan on the development of cold-induced hypertension in rats. ( Baron, A; Cade, JR; Fregly, MJ; Riesselmann, A, 1991) |
"An attenuation of adrenergic activity during the inhibition of endogenous angiotensin II formation was evaluated by determining plasma norepinephrine concentration after a single oral administration of captopril compared to that after nifedipine in essential hypertension." | 3.68 | Captopril attenuates reflex adrenergic response in essential hypertension. ( Masuyama, Y; Mohara, O, 1991) |
"The effects of the mineralocorticoid antagonist mespirenone on the development and maintenance of aldosterone-induced hypertension in Sprague-Dawley rats has been studied." | 3.68 | Effect of a new mineralocorticoid antagonist mespirenone on aldosterone-induced hypertension. ( Agarwal, M; Kalimi, M; Opoku, J; Qureshi, D, 1991) |
"This case of Conn's syndrome demonstrates long-term (seven years) efficacy of triamterene-thiazide therapy in controlling both hypertension and hypokalemia." | 3.68 | Long-term medical management of aldosterone-producing adenoma. ( Bornemann, M, 1990) |
" They investigated therefore in 15 patients with essential hypertension (EH) and in three patients with pheochromocytoma the urinary excretion of free noradrenaline (NA), adrenaline (A) and dopamine (DA), the plasma renin activity (PRA), the aldosterone concentration (PAC) and atrial natriuretic factor (ANF) in plasma, using radioimmunoanalysis, always before and 24 hours after clonidine administration (Haemiton retardR) by the oral route." | 3.68 | [The effect of clonidine on humoral factors in patients with arterial hypertension]. ( Dvoráková, J; Gregorová, I; Horký, K; Kopecká, J; Poliak, M, 1990) |
"Atrial natriuretic factor (ANF) may play a role in the regulation of the changes of blood volume and vascular reactivity during pregnancy and when pregnancy is complicated by hypertension." | 3.68 | Plasma atrial natriuretic factor levels during normal pregnancy and pregnancy complicated by diabetes mellitus and hypertension. ( Atkinson, AB; McCance, DR; McKnight, JA; Roberts, G; Sheridan, B; Traub, AI, 1990) |
" furosemide administration in 10 offsprings of normotensive subjects who had a normal Na(+)-K+ cotransport activity and in 26 normotensive men with a positive family history of essential hypertension." | 3.68 | Vasoactive humoral systems and sodium transport in erythrocytes of normotensive offsprings of essential hypertensive subjects. ( Bultasová, H; Janata, V; Pinsker, P, 1990) |
"Eight patients with mild to moderate uncomplicated essential hypertension who had been taking nifedipine 20 mg twice daily for at least six weeks." | 3.68 | Long term reduction in sodium balance: possible additional mechanism whereby nifedipine lowers blood pressure. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Pevahouse, JB; Sagnella, GA, 1990) |
" the main representatives of sodium retaining systems, and of the atrial natriuretic factor (ANF) the decisive natriuretic substance in acute expansion of the extracellular volume (ECV) by infusion of two litres of saline in six controls, seven patients with essential hypertension and liver cirrhosis without ascites (6 patients) and with ascites (6 patients)." | 3.68 | [Mutual interaction of the renin-angiotensin system and the atrial natriuretic factor in the renal response to acute volume loading]. ( Dvoráková, J; Gregorová, I; Horký, K; Srámková, J; Tesar, V, 1990) |
"The effect of a single oral dose (50 mg) of captopril was studied in 12 hypertensive patients divided into 2 groups: 6 had a normal hemodynamic profile; the other 6 had NYHA class III or IV heart failure." | 3.68 | [Captopril and hypertensive cardiopathy : therapeutic effects and hormonal changes]. ( D'Aprile, N; Faglia, S; Galli, M; Kristodhullu, S; Martorelli, T; Mondillo, S; Palazzuoli, V, 1990) |
"This study was undertaken to clarify the role of dopamine receptor (DA2) on the effects of atrial natriuretic polypeptide(ANP) on blood pressure, plasma and urinary cyclic GMP, and urinary sodium excretion, alpha-human ANP (alpha-hANP) was intravenously administrated to 7 normal subjects and 14 patients with essential hypertension as follows: first a dose of 0." | 3.68 | [The significance of cGMP and dopamine receptor on the natriuretic and hypotensive activities of synthetic atrial natriuretic polypeptide in essential hypertension]. ( Fukuchi, S; Haga, H; Kato, K; Kin, S; Kohno, H; Mori, K; Shigetomi, S; Tanaka, K; Tosaki, H, 1990) |
"This study investigated the ability of two diuretics, amiloride and frusemide, to prevent the development of ACTH induced hypertension in conscious sheep." | 3.68 | Amiloride blocks the onset of ACTH-induced hypertension in the sheep. ( Coghlan, JP; Reid, AF; Scoggins, BA; Whitworth, JA, 1990) |
"The effects of 1-year antihypertensive treatment with the diuretic fenquizone were evaluated in 16 patients with mild essential hypertension." | 3.68 | Hemodynamic and humoral effects of chronic antihypertensive treatment with fenquizone: importance of aldosterone response. ( Ambrosioni, E; Borghi, C; Boschi, S; Costa, FV; Mussi, A, 1990) |
"To evaluate the participation of the renin-angiotensin system in sustaining hypertension, we administered the specific dipeptide renin inhibitor enalkiren (A-64662) to 18 patients with essential hypertension." | 3.68 | Assessment of renin dependency of hypertension with a dipeptide renin inhibitor. ( Boger, RS; Essinger, I; Glassman, HN; Luther, R; Neutel, JM; Weber, MA, 1990) |
"The plasma aldosterone (A) and desoxycorticosterone (DOCS) levels were measured in 10 patients with primary aldosteronism and in 2 subgroups with low-renin hypertensive disease (LRHD): (1) those with normal adrenal glands++ (n - 11) and (2) those with structural changes in the cortex (n - 11)." | 3.68 | [Plasma mineralocorticoids--aldosterone and desoxycorticosterone-- in patients with"low-renin"arterial hypertension]. ( Bulkina, OS; Gorbacheva, ON; Levitskaia, IuV; Obtrakht, NV; Sokolova, RI; Ustinova, SE, 1990) |
"We examined the salt sensitivity of blood pressure in angiotensin II (ANG II)-induced hypertension." | 3.68 | Salt sensitivity in hypertensive rats with angiotensin II administration. ( Ando, K; Fujita, T; Sato, Y, 1990) |
"The effect of the direct renin inhibitor enalkiren (Abbott Laboratories) was examined in 8 healthy patients with essential hypertension." | 3.68 | Effects of renin inhibition in systemic hypertension. ( Anderson, PW; Boger, RS; Do, YS; Horton, R; Hsueh, WA; Luther, RR; Schambelan, M, 1990) |
"Hypertension in patients with NIDDM is frequently salt-sensitive, which may be due to sodium retention and enhanced vascular reactivity to angiotensin II." | 3.68 | Salt-sensitive blood pressure and exaggerated vascular reactivity in the hypertension of diabetes mellitus. ( Corry, D; Trujillo, A; Tuck, M, 1990) |
"There is evidence of crucial central nervous system involvement in the pathogenesis of mineralocorticoid-excess salt hypertension, as well as data indicating that corticosterone is the predominant ligand for the type I adrenocorticoid receptor in the brain." | 3.68 | ICV infusion of corticosterone antagonizes ICV-aldosterone hypertension. ( Fort, C; Gómez-Sánchez, EP; Thwaites, D; Venkataraman, MT, 1990) |
"Initial experiments demonstrated that a 1-h infusion of 10 ng/min angiotensin II (ANG II) into rats causes an increase in plasma aldosterone concentration (PAC) and that chronic administration of aldosterone alone to rats on increased sodium intake causes hypertension." | 3.68 | Role of aldosterone in angiotensin II-induced hypertension in rats. ( Fink, GD; Kanagy, NL; Pawloski, CM, 1990) |
"Ten male patients with essential hypertension were studied on a constant diet (100 mEq of sodium daily) while on placebo, immediately following a 20-mg oral dose of nitrendipine, and during 1 week of nitrendipine therapy (10 mg twice daily)." | 3.67 | Renal effects of nitrendipine monotherapy in essential hypertension. ( Barrett, JD; Eggena, P; Golub, MS; Sambhi, MP; Thananopavarn, C, 1984) |
"The converting enzyme inhibitor enalapril, in single daily doses of 10 to 40 mg, was given to 20 hypertensive patients with renal artery stenosis." | 3.67 | Enalapril in treatment of hypertension with renal artery stenosis. Changes in blood pressure, renin, angiotensin I and II, renal function, and body composition. ( Brown, JJ; Cumming, AM; Davies, DL; East, BW; Hodsman, GP; Lever, AF; Morton, JJ; Murray, GD; Robertson, JI, 1984) |
"Enalapril lowers blood pressure both acutely and during long-term therapy in patients with essential hypertension." | 3.67 | Plasma enalapril levels and hormonal effects after short- and long-term administration in essential hypertension. ( Casley, D; Cubella, R; Jackson, BJ; Johnston, CI; Larmour, I, 1984) |
"Forty to fifty percent of patients with essential hypertension are unable to modify their adrenal and renal vascular responses to angiotensin II with changes in sodium intake." | 3.67 | Converting enzyme inhibitors normalize the reduced adrenal responsiveness to angiotensin II in essential hypertension. ( Hollenberg, NK; Williams, GH, 1984) |
"The dependence of arteriolar vasoconstrictor tone on the activity of Na+,K+-ATPase was studied in 17 normotensive subjects (NT) and 28 patients with essential hypertension (EH) by measuring the response in forearm blood flow and vascular resistance to intraarterial infusion of the Na+,K+-ATPase inhibitor ouabain." | 3.67 | Forearm vasoconstrictor response to ouabain: studies in patients with mild and moderate essential hypertension. ( Bolli, P; Bühler, FR; Hulthén, UL; Kiowski, W, 1984) |
" Furthermore, acute and chronic administrations of clonidine were used to determine a participation of the sympathetic nervous system in the maintenance of hypertension in these patients." | 3.67 | Plasma catecholamines and autonomic nervous system function in patients with early renal insufficiency and hypertension: effect of clonidine. ( Campese, VM; Levitan, D; Massry, SG; Romoff, M, 1984) |
"The converting-enzyme inhibitor captopril (25-50 mg orally every 6 h for 66 h) was used to dissociate the circulating levels of angiotensin II (ANG II) from changes in sodium balance in 11 patients with normal renin essential hypertension on 10 mmol of sodium/day intake." | 3.67 | Captopril enhances vascular and adrenal responsiveness to angiotensin II in essential hypertension. ( Dluhy, RG; Gordon, MB; Hollenberg, NK; Koletsky, RJ; LeBoff, MS; Moore, TJ; Williams, GH, 1984) |
"Treatment of fifteen patients with essential hypertension over four weeks using the beta 1-adrenoceptor blocking agent, metoprolol, resulted in a decrease in 24 h urinary excretion of kallikrein and aldosterone along with a decrease in plasma renin activity." | 3.67 | Effect of metoprolol on 24-hour urinary excretion of adrenal steroids and kallikrein in patients with essential hypertension. ( Fritschka, E; Gotzen, R; Kittler, R; Schöneshöfer, M, 1984) |
"Timolol, a non-cardioselective beta-blocking agent, was administered orally after 2 weeks of placebo to 14 patients with essential hypertension for 8 weeks following 1-4 weeks of dose-ranging period." | 3.67 | Effects of timolol on blood pressure, systemic hemodynamics, plasma renin activity, and glomerular filtration rate in patients with essential hypertension. ( Bedogna, V; Fabris, A; Gammaro, L; Maschio, G; Ortalda, V; Tessitore, N; Valvo, E, 1984) |
"Potassium balance was followed in 12 subjects with hypertension during treatment either with timolol and hydrochlorothiazide or with timolol, hydrochlorothiazide, and amiloride." | 3.67 | Thiazide-induced potassium loss not prevented by beta blockade. ( Steiness, E, 1984) |
"Captopril, an orally active angiotensin-converting enzyme inhibitor, was administered to 15 patients with essential hypertension." | 3.67 | Acute effect of captopril on serum lipid peroxides level in hypertensive patients. ( Fukuchi, S; Gotoh, M; Mizuno, K, 1984) |
"Studies were carried out in 15 patients with renal insufficiency and hypertension to compare the long-term effects of methyldopa and propranolol on renal hemodynamics." | 3.67 | Comparison of long-term renal hemodynamic effects of methyldopa and propranolol in patients with hypertension and renal insufficiency. ( Alterman, L; Bank, DE; Bank, N; Lowenstein, I; Zelen, R, 1984) |
"Blood pressure, plethysmographically determined muscle blood flow in the calf at rest and during maximal dilatation, plasma renin activity, angiotensin II and plasma and urinary aldosterone were determined in normotensive men with a positive family history of hypertension (n = 17) and in an age- and weight-matched control group (n = 15) during usual sodium intake and after four weeks of increased salt intake." | 3.67 | Calf muscle haemodynamics and the renin-angiotensin-aldosterone system in normotensive subjects with a familial predisposition to hypertension: changes during increased salt intake. ( Andersson, OK; Aurell, M; Berglund, GL; Gudmundsson, O; Wikstrand, JM, 1984) |
"Aldosterone responses to posture and the dopamine antagonist, metoclopramide, were studied in seven normotensive controls and 12 patients with essential hypertension." | 3.67 | Enhanced response of plasma aldosterone to metoclopramide in essential hypertension. ( Eshkol, A; Lunenfeld, B; Rosenthal, T; Sowers, JR; Stern, N; Tuck, M, 1984) |
"The hypothesis that pregnancy induced hypertension (PIH) is associated with abnormal physiological control of plasma renin activity (PRA) was tested by studying the effects of graded infusion of angiotensin II (ANG II) on PRA, plasma aldosterone (PA), and blood pressure in normal pregnancy, PIH, non-pregnant women in luteal and follicular phase of the menstrual cycle, and males." | 3.67 | Failure of angiotensin II to reduce plasma renin activity in hypertensive pregnant women. ( Alcazar, JM; Garcia-Robles, R; Hammond, TG; Knox, FG; Paya, C; Rodicio, J; Romero, JC; Ruilope, L; Sancho-Rof, J, 1984) |
"To compare the effect of amiloride with that of oral potassium chloride (KCl) in hypokalemia, metabolic balance studies were carried out in hospitalized subjects with mild hypertension without edema who developed negative potassium balance after 4 days on hydrochlorothiazide (HCTZ)." | 3.67 | Oral potassium chloride and amiloride in hydrochlorothiazide-induced potassium loss. ( Barr, J; Chan, L; Maronde, RF; Spencer, CA; Vlachakis, ND, 1984) |
"In patients with mild hypertension, flurbiprofen in a dose of 100 mg daily for 7 days attenuated the hypotensive effect of a single dose of propranolol 80 mg but not of atenolol 100 mg." | 3.67 | Flurbiprofen interaction with single doses of atenolol and propranolol. ( Hawksworth, GM; McLean, I; Petrie, JC; Webster, J, 1984) |
"The responsiveness of plasma aldosterone to the infusion of angiotensin II at dose rates of 2, 4, and 10 ng/kg X min was assessed in 11 normal subjects and 13 patients with mild essential hypertension before and after 4 weeks of treatment with the sympatholytic agent debrisoquine." | 3.67 | Relationship between plasma aldosterone and angiotensin II before and after noradrenergic inhibition in normal subjects and patients with mild essential hypertension. ( Beretta-Piccoli, C; Bianchetti, MG; Boehringer, K; Link, L; Morton, JJ; Weidmann, P, 1984) |
"A 46-year-old woman with hypertension, normokalemia, suppressed renin, normal catecholamines, and a left adrenal mass on the CT scan was found to have excessive 18-hydroxycorticosterone (18-OHB) and normal aldosterone levels in plasma, both of which responded poorly to sodium restriction and angiotension II, and supranormally to ACTH." | 3.67 | Adrenal adenoma with 18-hydroxycorticosterone excess and hypertension: a variant of aldosteronomas. ( Azukizawa, S; Hosojima, H; Imaizumi, N; Kigoshi, T; Morimoto, S; Uchida, K; Yamamoto, I, 1984) |
"A single dose of doxazosin, a long-acting postsynaptic alpha 1-adrenoceptor antagonist, was administered to seven patients with essential hypertension." | 3.67 | Antihypertensive effects and pharmacokinetics of single and consecutive administration of doxazosin in patients with mild to moderate essential hypertension. ( Kaneko, Y; Miyajima, E; Miyakawa, T; Shionoiri, H; Takagi, N; Umemura, S; Yasuda, G; Yoshimura, H, 1987) |
" For this purpose, in a group of 11 patients with essential hypertension we have compared the blood pressure lowering effects of a single oral dose of nifedipine before (100 mmol Na+/day and 40 mmol K+/day) and after sodium depletion (20 mmol Na+/day and 40 mmol K+/day: each period was of 6-8 day duration)." | 3.67 | Effects of different sodium intakes on the antihypertensive and renal effects of single oral doses of nifedipine in hypertensive patients. ( Bolla, G; Cuspidi, C; Gradnik, R; Leonetti, G; Rupoli, L; Sangiorgio, P; Zanchetti, A, 1987) |
"The principal aim of this study was to investigate the effects of ketanserin on peripheral vascular pressor mechanisms in nine patients with essential hypertension, including an assessment of the responsiveness to intravenous infusions of the alpha 1-adrenergic agonist, phenylephrine, and the nonadrenergic vasoconstrictor, angiotensin II." | 3.67 | Effects of ketanserin on peripheral vascular pressor mechanisms in essential hypertension. ( Donnelly, R; Elliott, HL; Reid, JL, 1988) |
" Eight patients with essential hypertension were challenged with an infusion of 32 mmol of potassium chloride in saline before and after control of their blood pressure by the angiotensin converting-enzyme (ACE) inhibitor enalapril." | 3.67 | Effect of angiotensin converting-enzyme inhibition on potassium-mediated aldosterone secretion in essential hypertension. ( Barnes, JN; Drew, PJ; Furniss, SS; Goodwin, FJ; Holly, JM; Knight, AR; Skehan, JD, 1985) |
"Glomerular filtration rate (GFR) and tubular function were measured by means of the lithium clearance technique in 14 patients with renovascular hypertension (RVH) and eight patients with essential hypertension (EH) before and after oral administration of captopril 25 mg." | 3.67 | Abnormal glomerular and tubular function during angiotensin converting enzyme inhibition in renovascular hypertension evaluated by the lithium clearance method. ( Amdisen, A; Danielsen, H; Eiskjaer, H; Hansen, HH; Jensen, FT; Jespersen, B; Madsen, B; Nielsen, HK; Pedersen, EB; Sørensen, SS, 1989) |
"In patients with essential hypertension and healthy controls, plasma levels of atrial natriuretic peptide (ANP), angiotensin II (Ang II), aldosterone (Aldo), arginine vasopressin (AVP) and urinary excretion of prostaglandin E2 (PGE2) were measured under basal conditions, and before and after acute volume expansion with a 2." | 3.67 | Atrial natriuretic peptide and exaggerated natriuresis during acute hypertonic volume expansion in essential hypertension. ( Amdisen, A; Danielsen, H; Pedersen, EB; Sørensen, SS, 1989) |
"The author reviews contemporary views on the pathogenetic participation of selected humoral factors (of the renin-angiotensin-aldosterone system, natriuretic hormone and atrial natriuretic factor) in the development of arterial hypertension in humans." | 3.67 | [Humoral mechanisms in the pathogenesis of arterial hypertension with emphasis on the renin-angiotensin-aldosterone system and natriuretic substances]. ( Horký, K, 1989) |
"The relationship between atrial natriuretic factor (ANF), the renin-aldosterone axis, and blood pressure reduction with weight loss was investigated in 18 obese subjects (five hypertensive and 13 normotensive) placed on a 12-week, low-sodium (40 mmol), weight-reducing diet." | 3.67 | Weight reduction decreases atrial natriuretic factor and blood pressure in obese patients. ( McMurray, RW; Vesely, DL, 1989) |
"Patients with normal- or high-renin non-modulating essential hypertension fail to shift their adrenal sensitivity on a low sodium diet in response to an infusion of angiotensin II (Ang II)." | 3.67 | Prolonged converting enzyme inhibition in non-modulating hypertension. ( Dluhy, RG; Hollenberg, NK; Smith, K; Taylor, T; Williams, GH, 1989) |
"To elucidate mechanisms of angiotensin II (Ang II)-related hypertension, we infused angiotensin (76 ng/min s." | 3.67 | Angiotensin-induced hypertension in the rat. Sympathetic nerve activity and prostaglandins. ( Demmert, G; Ganten, D; Kühn, R; Luft, FC; Rohmeiss, P; Sterzel, RB; Unger, T; Wilcox, CS, 1989) |
" All animals were treated from 4 wk of age with captopril (100 mg/kg/day in drinking water) to prevent development of hypertension so that changes in responsiveness could not be attributed to disparate base-line blood pressures or to hypertension-induced injury of the cardiovascular system." | 3.67 | Enhanced slow-pressor response to angiotensin II in spontaneously hypertensive rats. ( Jackson, EK; Li, P, 1989) |
" Parameters measured included blood pressure, blood chemistry (serum creatinine, uric acid, blood urea nitrogen, blood glucose total cholesterol, and electrolytes), plasma renin activity, and plasma aldosterone concentration." | 3.67 | Effects of nicardipine on blood pressure and renal function in elderly hypertensive patients with renal dysfunction. ( Saruta, T, 1989) |
" In this study, nifedipine was administered in doses of 40 to 80 mg/day to 14 patients with essential hypertension, and its hemodynamic effects were evaluated by non-invasive methods, and its effect on glucose metabolism by an arginine infusion test." | 3.67 | Hemodynamic and endocrine effects of acute and chronic administration of nifedipine. ( Chiasson, JL; Larochelle, P; Parent, R, 1989) |
"Nine hypertensive patients with mild to moderate renal dysfunction were entered into a protocol to assess the blood pressure, humoral and renal effects of the angiotensin converting enzyme inhibitor, Benazepril (CGS14824A, 2 to 20 mg twice daily) in patients with hypertension and moderate renal insufficiency (mean creatinine clearance 56 ml/min/1." | 3.67 | Effect of benazepril monotherapy in subjects with hypertension associated with renal dysfunction. ( Bauer, JH; Lau, A; Reams, GP, 1989) |
"We studied the effects of intravenous injections of the renin inhibitor A-64662 on blood pressure, plasma renin activity (PRA), angiotensin II (Ang II) and aldosterone levels in patients with essential hypertension." | 3.67 | Renin inhibition with A-64662: effect on blood pressure and hormonal response in man. ( Bauer, JH; Bursztyn, M; Gavras, H; Gavras, I; Melby, JC; Tifft, CP, 1989) |
"Effects of a single administration of captopril on plasma and urinary vasopressin (AVP) were examined in 8 normotensive (NT) female volunteers, 17 patients with essential hypertension (EHT) and 2 patients with primary aldosteronism (PA)." | 3.67 | Effect of single-administration captopril on plasma and urinary vasopressin in normotensive subjects and patients with essential hypertension and primary aldosteronism. ( Fujishima, M; Kimura, Y; Muratani, H; Nakao, Y; Takishita, S; Tomita, Y; Tsuchihashi, T; Ueno, M, 1989) |
" Nonmodulating hypertension in part is characterized by decreased aldosterone secretion in response to angiotensin II (AII) as well as a decreased natriuretic response to a saline load." | 3.67 | The role of dopamine in nonmodulating hypertension. ( Conlin, PR; Gordon, MS; Hollenberg, NK; Steunkel, CA; Williams, GH, 1989) |
"In 16 patients with essential hypertension the effects of enalapril 20 mg once daily were compared with those of atenolol 50 mg once daily, with the two drugs in combination and with placebo using a double-blind cross-over design with allocation of treatment order by randomised Latin squares." | 3.67 | Enalapril and atenolol in essential hypertension: attenuation of hypotensive effects in combination. ( Bune, AJ; Cain, MD; Chalmers, JP; Morris, MJ; Russell, AE; Southgate, DO; West, MJ; Wing, LM, 1988) |
"The effects of ovine corticotropin releasing factor (o-CRF) on plasma aldosterone, 18-OH-corticosterone (18-OHB), plasma adrenocorticotropin (ACTH) and cortisol were determined in eight patients with primary aldosteronism, six with aldosterone-producing adenoma (APA) and two with idiopathic hyperaldosteronism (IHA)." | 3.67 | Effects of corticotropin-releasing factor (CRF) on aldosterone and 18-hydroxycorticosterone in essential hypertension and primary aldosteronism. ( Ikeda, M; Koshida, H; Matsubara, T; Miyamori, I; Morise, T; Okamoto, S; Takeda, R; Takeda, Y; Vecsei, P; Yasuhara, S, 1987) |
" Fenoldopam, the first selective DA1-receptor agonist that can be administered to man, was infused intravenously in 17 patients with essential hypertension (mean blood pressure 152/101 mm Hg)." | 3.67 | Augmentation of renal blood flow and sodium excretion in hypertensive patients during blood pressure reduction by intravenous administration of the dopamine1 agonist fenoldopam. ( Douglas, FL; Frederickson, ED; Goldberg, LI; McCoy, CE; Murphy, MB; Weber, RR, 1987) |
"This study was designed to examine the mechanisms that contribute to the chronic hypotensive effects of verapamil during angiotensin II-induced hypertension." | 3.67 | Chronic hypotensive effects of verapamil in angiotensin hypertension are steroid independent. ( Lohmeier, TE; Montani, JP; Rushing, EL; Smith, MJ, 1989) |
"Thirteen patients with hypertension and normal renal function received nitrendipine, a calcium entry blocker." | 3.67 | Nitrendipine, a calcium-entry blocker. Renal and humoral effects in human arterial hypertension. ( Bravo, EL; Fouad, FM; Pedrinelli, R; Tarazi, RC; Textor, SC, 1986) |
"To study the effects of Ca antagonists on hypertension induced cardiac and vascular hypertrophy, diltiazem, at the doses of 30 and 60 mg/kg, p." | 3.67 | [Effects of diltiazem on developing blood pressure and accompanying cardiac and vascular hypertrophy in SHR]. ( Inamasu, M; Iwasaki, HO; Morita, T; Nagao, T; Narita, H, 1985) |
" These studies were performed in patients with essential hypertension who were maintained on a constant sodium intake (100 mmol/day), before and after 5 days of treatment with ibopamine, an orally active dopamine analogue." | 3.67 | Dopaminergic control of aldosterone secretion is not mediated by atrial natriuretic factor in patients with essential hypertension. ( Ambrosi, B; Ardeleani, G; Ferraris, P; Morganti, A; Quorso, P; Sala, C; Venegoni, P; Zanchetti, A, 1988) |
"To assess the pathophysiological role of atrial natriuretic factors in mineralocorticoid hypertension, we studied the effects of chronic infusion of synthetic atrial natriuretic factor on blood pressure and sodium-water excretion in rats with aldosterone salt-induced hypertension." | 3.67 | Effects of chronically administered atrial natriuretic factor in aldosterone-infused hypertensive rats. ( Abe, K; Hiwatari, M; Kanazawa, M; Kohzuki, M; Saito, T; Saso, S; Yasujima, M; Yoshida, K; Yoshinaga, K, 1988) |
" The present study evaluated plasma beta-endorphin, ACTH, cortisol, and aldosterone levels in patients with IHA (n = 10), aldosterone-producing adenomas (n = 4), essential hypertension (n = 11), and normal subjects (n = 10)." | 3.67 | Plasma beta-endorphin levels in primary aldosteronism. ( Berelowitz, B; Griffing, GT; Hudson, M; Manson, JA; McIntosh, T; Melby, JC; Salzman, R, 1985) |
"Based on their previous observations of the stimulating action of verapamil on the secretory reserve of cortisol after one-week oral administration to healthy volunteers, the author investigated the effect of this calcium entry blocker on the adrenocortical function (cortisol and aldosterone secretion) during therapeutic administration to patients with mild arterial hypertension and normotensive patients suffering from Raynaud's syndrome." | 3.67 | The effect of long-term verapamil treatment on the secretion of cortisol and aldosterone in subjects with normal and high blood pressure. ( Zofková, I, 1985) |
"The acute antihypertensive effect of a new long-acting oral angiotensin I-converting enzyme (ACE) inhibitor, enalapril maleate, was assessed in 20 hypertensive patients, of whom 14 had essential hypertension, 4 had renovascular hypertension, one had hypertension associated with chronic renal failure, and one had primary aldosteronism." | 3.67 | [The acute effects of the new angiotensin I-converting enzyme inhibitor, enalapril maleate, on blood pressure, plasma renin, aldosterone and kinins in hypertensive patients]. ( Fukuchi, S; Gotoh, M; Hashimoto, S; Kunii, N; Mizuno, K, 1985) |
"The purpose of this study was to evaluate the natriuretic effect and renal haemodynamic changes induced by enalapril in patients with essential hypertension." | 3.67 | Natriuretic effect and changes in renal haemodynamics induced by enalapril in essential hypertension. ( Brito, M; Gilbert, HB; Giménez, M; Marcó, E; Moledo, LI; Raffaele, P; Sánchez, RA, 1985) |
"In 15 patients with mild-to-moderate essential hypertension a new orally active angiotensin converting enzyme inhibitor, 1-(D-3-acetylthio-2-methylpropanoyl)-L-prolyl-L-phenylalanine (Alacepril), was administered with a single oral dose of 50 mg to evaluate its antihypertensive effect." | 3.67 | Acute effects of the new oral angiotensin converting enzyme inhibitor 1-(D-3-acetylthio-2-methylpropanoyl)-L-prolyl-L-phenylalanine (Alacepril) in essential hypertension. ( Fukuchi, S; Hashimoto, S; Kunii, N; Mizuno, K; Niimura, S; Tani, M; Watari, H; Yabe, R, 1985) |
"We evaluated the effect of additional chlorthalidone therapy on blood pressure and body fluid volumes in 10 patients with essential hypertension who did not respond to chronic converting enzyme inhibition with enalapril." | 3.67 | Changes in blood pressure and body fluid volumes during diuretic therapy in patients with essential hypertension who receive enalapril. ( Geyskes, GG; Mees, EJ; Roos, JC; van Schaik, BA, 1986) |
"To investigate whether dopamine plays a role in the regulation of aldosterone secretion during long-term blockade of the renin-angiotensin system, we studied the effect of metoclopramide, a competitive antagonist of dopamine, in 6 patients with essential hypertension chronically treated with the angiotensin converting enzyme inhibitor enalapril." | 3.67 | Dopaminergic control of aldosterone secretion in hypertensive patients chronically treated with an angiotensin converting enzyme inhibitor. ( Brunner, HR; Gomez, HJ; Nussberger, J; Schaller, MD; Waeber, B, 1986) |
" In its severe form, hypertension and hypokalemic alkalosis are present, owing to increased secretion of the sodium-retaining corticoids, corticosterone and deoxycorticosterone." | 3.67 | Cortisol resistance in man. ( Brandon, DD; Chrousos, GP; De Vroede, MM; Lipsett, MB; Loriaux, DL; Tomita, M, 1986) |
"The time course of the blood pressure lowering effect and the dose-response relationship of the new angiotensin converting enzyme inhibitor ramipril (HOE 498) were studied in 8 patients, with essential hypertension." | 3.67 | Studies on the antihypertensive effect of single doses of the angiotensin converting enzyme inhibitor ramipril (HOE 498) in man. ( Böhm, RO; Rahn, KH; van Baak, MA, 1986) |
"The angiotensin converting enzyme (ACE) inhibitor captopril proved to be an effective antihypertensive drug during a 5-year follow-up study of patients with severe hypertension who had been resistant to a triple-drug regimen." | 3.67 | [Results of a 5-year study with captopril in patients with severe therapy-resistant hypertension]. ( Scheler, F; Schoel, G; Schrader, J, 1986) |
"Nifedipine, in a slow release preparation, was given at a mean daily dosage of 47 +/- 4 mg to 12 patients with severe hypertension in whom arterial pressure was not satisfactorily controlled (mean blood pressure, 172 +/- 6/111 +/- 4 mmHg) by the association of a converting enzyme inhibitor and a diuretic." | 3.67 | Effect of nifedipine in hypertension not controlled by converting enzyme inhibitor and diuretic. ( Mimran, A; Ribstein, J, 1986) |
"Thirteen subjects with essential hypertension controlled on oral enalapril (20 mg/day) therapy were entered into a protocol to assess serially 24-hour blood pressure, the renin-angiotensin-aldosterone system, angiotensin-converting enzyme activity, and plasma and urine enalaprilat drug levels, following both chronic oral administration of enalapril and its replacement with intravenous enalaprilat." | 3.67 | Enalaprilat: an intravenous substitute for oral enalapril therapy. Humoral and pharmacokinetic effects. ( Bauer, JH; Lal, SM; Reams, GP; Whalen, JJ, 1986) |
"0] octane-3-carboxylic acid (ramipril, Hoe 498) were investigated in 10 patients with essential hypertension (WHO stage I or II)." | 3.67 | Humoral and blood pressure effects of the angiotensin converting enzyme inhibitor ramipril in essential hypertension. ( Distler, A; Eckert, HG; Haller, H; Irmisch, R; Lenz, T; Metzger, H; Meyer-Sabellek, W; Philipp, T; Tansey, MJ; Wilp, C, 1986) |
"Captopril effects were studied in 27 patients with second-stage essential hypertension following administration of a single 25 mg oral dose of the drug." | 3.67 | [Mechanisms of the hypotensive action of captopril in essential hypertension]. ( Chernova, NA; Parfenova, EV; Uchitel', IA; Ustinova, SE; Zhukova, IM, 1986) |
"Hyperresponsiveness of plasma aldosterone to metoclopramide (MCP) was found in the patients with secondary aldosteronism." | 3.67 | [Influence of endogenous renin-angiotensin system on plasma aldosterone responsiveness to metoclopramide]. ( Iwasaki, Y, 1987) |
"Plasma renin activity (PRA) and plasma aldosterone concentration (PAC) were measured in 19 cases with primary aldosteronism (PA) and 72 with essential hypertension (EHT) to differentiate the two disorders in the following conditions: after overnight recumbency (basal state) and after oral administration of captopril." | 3.67 | Single oral administration of captopril may not bring an improvement in screening of primary aldosteronism. ( Abe, I; Fujishima, M; Kawasaki, T; Kawazoe, N; Muratani, H; Takishita, S; Tomita, Y; Tsuchihashi, T; Ueno, M, 1987) |
" Values for serum and urinary calcium, phosphorus, magnesium and electrolytes, creatinine clearance, plasma immunoreactive parathyroid hormone, and serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D were similar in both study groups on each diet." | 3.67 | Normal vitamin D and mineral metabolism in essential hypertension. ( Bell, NH; Epstein, S; Hughes, GS; Margolius, HS; Oexmann, MJ, 1988) |
"The role of central pressor mechanisms in the maintenance of blood pressure in six hypertensive patients with angiographically proven unilateral renal artery stenosis was investigated by studying the haemodynamic and hormonal responses before and after central sympathetic blockade with clonidine." | 3.67 | Cardiovascular and neurohormonal changes following central sympathetic blockade with clonidine in human unilateral renal artery stenosis. ( Kooner, JS; Mathias, CJ; Peart, S, 1988) |
"The magnitude of captopril hypotensive effect, and variation in renin-angiotensin-aldosterone and kallikrein-kinin parameters were examined in patients with advanced essential hypertension in the presence of normal and low plasma renin activity." | 3.67 | [Changes in the indicators of the renin-angiotensin-aldosterone system, kallikrein-kinin system and arterial blood pressure in elderly patients with essential hypertension treated with captopril]. ( Beuer, E; Brozovskiĭ, KKh; Faulhaber, H; Gurke, R; Khartrodt, V, 1988) |
"In 35 initially normotensive patients with chronic glomerulonephritis and lupus nephritis (including 27 patients with nephrotic syndrome; NS), blood pressure (BP), urinary sodium excretion, plasma renin activity (PRA), plasma aldosterone level (PA), urinary aldosterone excretion (Au and blood volume were measured before and during prednisolone treatment." | 3.67 | Steroid-induced hypertension in patients with nephrotic syndrome. ( Klepikov, PV; Kutyrina, IM; Tareyeva, IE, 1988) |
"We investigated the effect of an orally administered, long-acting, beta-adrenergic blocking agent, penbutolol, on the circadian rhythm of blood pressure (BP) and heart rate (HR), and plasma renin activity (PRA), aldosterone (PA) and cortisol (PC) levels in hospital patients with essential hypertension validated by a chronobiological inferential statistic method." | 3.67 | Effect of penbutolol on circadian blood pressure, and renin, aldosterone and cortisol levels in patients with essential hypertension. ( Bianconi, M; degli Uberti, EC; Margutti, A; Pansini, R; Portaluppi, F; Rossi, R; Teodori, V; Trasforini, G, 1988) |
"The validity of the captopril test for primary aldosteronism (PA) was tested in patients with surgically verified PA (n = 12) or essential hypertension (EHT, n = 20) with different levels of sodium intakes." | 3.67 | Effects of sodium intake on the captopril test for primary aldosteronism. ( Iwaoka, T; Naomi, S; Sato, T; Umeda, T, 1987) |
" Lasilactone, a new combination diuretic (furosemide 20 mg and spironolactone 50 mg) was evaluated in 30 patients with mild-to-moderate essential hypertension." | 3.67 | Efficacy and safety of lasilactone, a new combination diuretic, in essential hypertension. ( Birbari, AE; Daouk, MM; Mukaddam-Daher, S, 1987) |
"In order to evaluate whether changes in the plasma concentration of aldosterone (PA) following the administration of captopril, an inhibitor of angiotensin-converting enzyme, will establish the diagnosis of primary aldosteronism we have used this test in 9 healthy subjects and in 22 patients with various forms of hypertension, including 5 patients with primary aldosteronism due to idiopathic adrenal hyperplasia (n = 4) or aldosterone-producing adenoma (n = 1)." | 3.67 | [Detection of primary aldosteronism using the captopril test]. ( Graninger, W; Nowotny, P; Pirich, K; Vierhapper, H; Waldhäusl, W, 1987) |
"We studied natriuresis during central hypervolaemia by immersing eight normal subjects and eight patients with uncomplicated essential hypertension up to the neck in water, either in the absence (study 1) or presence (study 2) of dopamine blockade by metoclopramide." | 3.67 | Dopamine blockade abolishes the exaggerated natriuresis of essential hypertension. ( Biggi, A; Coruzzi, P; Musiari, L; Novarini, A; Ravanetti, C, 1987) |
"Oral administration of felodipine to 10 patients with mild essential hypertension acutely reduced the brachial artery pressure by 15/13mm Hg." | 3.67 | Effects of felodipine and metoprolol on blood pressure, plasma renin, angiotensin II, aldosterone and catecholamines in hypertensive patients. ( Amery, A; De Schaepdryver, A; Fagard, R; Lijnen, P; Moerman, E; Staessen, J, 1987) |
"The immediate effects of intravenous diltiazem effects and short-term (4 weeks) of the oral drug on systemic and regional hemodynamics, cardiac structure, and humoral responses were evaluated by previously reported methods in nine patients with mild-to-moderate essential hypertension and in one patient with primary aldosteronism." | 3.67 | Immediate and short-term hemodynamic effects of diltiazem in patients with hypertension. ( Amodeo, C; Frohlich, ED; Kobrin, I; Messerli, FH; Ventura, HO, 1986) |
"The effect of angiotensin converting enzyme inhibition by captopril (CAP) on serum potassium (SK) changes was studied during a three-hour glucose tolerance test (GTT) in recumbent and upright positions in 16 patients with drug-resistant hypertension." | 3.67 | Interplay of various factors in glucose-induced hyperkalemia during captopril treatment. ( Bános, C; Gercsák, G; Radó, JP, 1986) |
"The cardiovascular pressor responses to a stepwise increase in plasma norepinephrine or angiotensin II concentrations, induced by infusions, were studied in 23 normotensive subjects with a negative and 25 with a positive family history of essential hypertension." | 3.67 | Blood pressure control in normotensive members of hypertensive families. ( Beretta-Piccoli, C; Bianchetti, MG; Ferrier, C; Weidmann, P, 1986) |
"The influence of long-term nifedipine treatment on body fluid compartments, renal function, the renin-angiotensin system, and the adrenergic system was studied in 18 patients with essential hypertension." | 3.67 | Lack of effect of nifedipine on counterregulatory mechanisms in essential hypertension. ( Bruun, NE; Hartling, OJ; Ibsen, H; Moelbak, AG; Nielsen, F; Nielsen, MD, 1986) |
"Plasma renin activity (PRA) and plasma aldosterone concentration (PAC) were measured in 19 cases with primary aldosteronism (PA) and in 72 with essential hypertension (EHT) to differentiate the two disorders during the following conditions on normal salt diet: after overnight recumbency (basal state) and 2 hours after oral administration of 25 mg of captopril." | 3.67 | Is single oral administration of captopril beneficial in screening for primary aldosteronism? ( Abe, I; Kawasaki, T; Kawazoe, N; Kimura, Y; Muratani, H; Takishita, S; Tomita, Y; Tsuchihashi, T; Ueno, M; Uezono, K, 1986) |
"The effect of 8 weeks treatment with the calcium antagonist felodipine--a new long-acting dihydropyridine derivative--in a dose of 10 mg twice daily was studied in 10 male patients with essential hypertension, WHO grade I-II, aged 25-62 years." | 3.67 | The effect of 8 weeks treatment with the calcium antagonist felodipine on blood pressure, heart rate, working capacity, plasma renin activity, plasma angiotensin II, urinary catecholamines and aldosterone in patients with essential hypertension. ( Hökfelt, B; Hulthén, UL; Katzman, PL, 1986) |
"The effects of a calcium antagonist [Nicardipine hydrochloride (NH)] on the prostaglandin [prostaglandin E2 (PGE2), and 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha)] and thromboxane B2 levels in the blood and urine were examined in 6 patients with essential hypertension following intravenous infusion of NH for 120 minutes." | 3.67 | Effects of intravenous administration of a calcium antagonist on prostaglandins and thromboxane in plasma and urine in humans. ( Fukuda, N; Hatano, M; Honda, M; Izumi, Y; Manabe, R; Minato, M; Watanabe, M, 1986) |
"The effect of exogenous angiotensin II on plasma renin activity (PRA), plasma renin concentration (PRC) and plasma aldosterone (PA) was investigated in a group of 8 patients with essential hypertension after one year of captopril therapy." | 3.67 | Effect of exogenous angiotensin II infusion after one year of captopril therapy in essential hypertension. ( Hammond, TG; Miranda, B; Robles, RG; Rodicio, JL; Romero, JC; Ruilope, LM; Sancho, J, 1986) |
"7 years, with systemic systolic hypertension were studied before and after 1 month of therapy with oral hydrochlorothiazide, 50 mg/day." | 3.67 | Systemic systolic hypertension in the elderly: correlation of hemodynamics, plasma volume, renin, aldosterone, urinary metanephrines and response to thiazide therapy. ( Dunsky, MH; Hill, NE; Mookherjee, S; Smulyan, H; Vardan, S; Warner, RA, 1986) |
"Oral administration of felodipine to 10 patients with mild essential hypertension acutely reduced systemic vascular resistance (SVR) by 40% after 30 min." | 3.67 | Acute haemodynamic and humoral responses to felodipine and metoprolol in mild hypertension. ( Amery, A; Fagard, R; Lijnen, P; Moerman, E; Staessen, J, 1987) |
"Plasma concentrations of arginine vasopressin (AVP), angiotensin II (AII), aldosterone (Aldo), urinary output (V), osmolar clearance (Cosm), free water clearance (CH2O), fractional excretions of sodium (FENa) and potassium (FEK), urinary sodium excretion rate (U-Na) and serum potassium (S-K) were determined in 9 patients with essential hypertension (group I) and 13 normotensive healthy control subjects (group II) before and three times during the first 4 hours after an intravenous injection of 40 mg of furosemide." | 3.67 | Abnormal vasopressin and aldosterone response to furosemide in essential hypertension. ( Danielsen, H; Madsen, M; Pedersen, EB; Sørensen, SS; Thomsen, OO, 1986) |
"This study assessed renal sodium handling in a group of patients with essential hypertension in whom control of the renal blood supply and aldosterone release by angiotensin II is abnormal ("non-modulating") because of recent evidence that these patients have sodium-sensitive hypertension." | 3.67 | Abnormal renal sodium handling in essential hypertension. Relation to failure of renal and adrenal modulation of responses to angiotensin II. ( Hollenberg, NK; Moore, T; Rabinowe, S; Redgrave, J; Shoback, D; Williams, GH, 1986) |
"Plasma aldosterone, 18-hydroxycorticosterone (18-OH-B), 18-hydroxydeoxycorticosterone (18-OH-DOC), corticosterone, cortisol and prolactin levels were determined during an angiotensin II infusion at increasing rates both with and without a simultaneous infusion of dopamine in seven normotensive subjects, in ten patients with essential hypertension, and in ten patients with primary aldosteronism." | 3.67 | Dopamine reduces aldosterone and 18-hydroxycorticosterone response to angiotensin II in patients with essential low-renin hypertension and idiopathic hyperaldosteronism. ( Lorenz, R; von Werder, K; Weber, PC; Witzgall, H, 1985) |
"The effects of chronic dietary salt-loading and nifedipine therapy on hypertension-prone (SBH), -resistant (SBN) and parental (SB) Sabra rats were investigated." | 3.67 | Salt-induced hypertension in the 'Sabra' rat strain: influence of nifedipine treatment. ( Ben-Ishay, D; Ebsen, W; Garthoff, B; Kazda, S; Luckhaus, G, 1985) |
"The effects of orally administered glandular kallikrein on urinary kallikrein, aldosterone and prostaglandin E (PGE) excretion, plasma renin activity (PRA), immunoreactive 6-keto PGF1 alpha and thromboxane B2 concentrations and platelet aggregation were studied in 12 patients with essential hypertension (EH)." | 3.67 | Effects of orally administered glandular kallikrein on urinary kallikrein and prostaglandin excretion, plasma immunoreactive prostanoids and platelet aggregation in essential hypertension. ( Ban, M; Ito, T; Mochizuki, M; Ogawa, K; Satake, T, 1985) |
"Long-term treatment with muzolimine in patients with essential hypertension has provided very interesting results." | 3.67 | Is the antihypertensive effect of muzolimine due to volume depletion? ( Andreucci, VE; Cofelice, E; Dal Canton, A; Oliva, O; Romano, G; Russo, D; Veniero, P, 1985) |
"Two patients with hypertension due to coarctation of the aorta were treated for 12 weeks with captopril at increasing doses." | 3.67 | Resistance to captopril in hypertension of coarctation of the aorta. ( Fallo, F; Mantero, F; Maragno, I, 1985) |
"In order to investigate the validity of angiotensin converting enzyme inhibition with captopril as a screening test for primary aldosteronism (PA), 50 mg of captopril were administered orally to 7 patients with PA, 17 with essential hypertension (EH), 5 with renovascular hypertension (RVH), 2 with renoparenchymal hypertension (RH) and 8 normal volunteers." | 3.67 | Clinical evaluation of the captopril screening test for primary aldosteronism. ( Fujii, Y; Hamasaki, S; Inoue, J; Iwaoka, T; Miura, F; Naomi, S; Sato, T; Umeda, T, 1985) |
"Mean arterial blood pressure, forearm vascular resistance, plasma norepinephrine, plasma renin activity and aldosterone responses to graded lower body negative pressure and tilt at 80 degrees were examined in 10 men with mild to moderate essential hypertension before and after 12 weeks of diltiazem (240 to 360 mg/day) therapy." | 3.67 | Effects of diltiazem on hormonal and hemodynamic responses to lower body negative pressure and tilt in patients with mild to moderate systemic hypertension. ( Beck, F; McNamara, C; Mohanty, PK; Sowers, JR; Thames, MD; Welch, B, 1985) |
"Cardiovascular, baroreflex and humoral responses were evaluated in 8 patients with essential hypertension during a control period and then after oral treatment for 5 days with nicardipine hydrochloride 60 mg/d, a calcium channel antagonist." | 3.67 | Cardiovascular, baroreflex and humoral responses in hypertensive patients during nicardipine therapy. ( Biggi, A; Coruzzi, P; Musiari, L; Novarini, A; Ravanetti, C, 1985) |
"The responses of plasma renin activity (PRA), plasma bradykinin (BK) and urinary kallikrein like activity (UK) associated with the infusion of angiotensin II (AII) before and after NaCl loading were investigated in pregnancy induced hypertension (PIH)." | 3.67 | [Studies on the pathophysiology of pregnancy induced hypertension--endocrinological analysis by the method of angiotensin II and NaCl loading]. ( Mochizuki, M; Morikawa, H; Yamasaki, M, 1985) |
"Exchangeable sodium, blood volume, plasma norepinephrine (NE), epinephrine, renin and aldosterone levels, and pressor responses to infused NE or angiotensin II (AII) were assessed in ten patients with essential hypertension on placebo, following 6 to 8 weeks of calcium-antagonist nifedipine (NIF), 3 X 10 to 20 mg/day, and after 6 to 8 weeks on NIF combined with the diuretic chlorthalidone (CHLOR), 25 to 50 mg/day." | 3.67 | Body sodium-blood volume state, aldosterone, and cardiovascular responsiveness after calcium entry blockade with nifedipine. ( Beretta-Piccoli, C; Bianchetti, MG; Bomio, F; Luisoli, S; Marone, C; Weidmann, P, 1985) |
"Radioimmunoassays of plasma hormones were carried out, and correlation coefficients between the blood somatotrophin level and blood thyrotrophic hormone, thyroxine, renin, and aldosterone, as well as between blood somatotrophin and diastolic BP, cardiac index, total peripheral resistance, the tension and ejection time, cardiac cycle duration and electrocardiographic SV1 + RV5, were calculated in 95 patients with essential hypertension and symptomatic arterial hypertensions." | 3.67 | [Concentration of somatotropic hormone in the blood in arterial hypertension of different origin]. ( Morozov, AI; Selivonenko, VG, 1985) |
"Studies have been conducted to determine which, if any, of the parameters governing active Na-K transport (K and/or ouabain sensitive) are altered in vascular smooth muscle during mineralocorticoid-salt hypertension." | 3.67 | Alterations in active Na-K transport during mineralocorticoid-salt hypertension in the rat. ( Jones, AW; Magliola, L; McMahon, EG, 1986) |
"Serum 18-hydroxycorticosterone, aldosterone, and potassium were measured under basal conditions in 34 patients with documented primary aldosteronism, 10 patients with essential hypertension, and 9 normal subjects." | 3.67 | The prediction of anatomical morphology of primary aldosteronism using serum 18-hydroxycorticosterone levels. ( Brown, RD; Hanson, CS; Hollifield, JW; Kem, DC; Painton, R; Tang, K; Weinberger, MH, 1985) |
"Experiments were performed to characterize the hypertension produced by chronic intracerebroventricular (ICV) infusion of angiotensin II (ANG II) in conscious rats." | 3.67 | Sodium-dependent hypertension produced by chronic central angiotensin II infusion. ( Bruner, CA; Fink, GD; Weaver, JM, 1985) |
"In earlier studies by our group it was shown that the urinary tetrahydroaldosterone excretion is a more reliable test for the diagnosis of primary aldosteronism than aldosterone-18-glucuronide ('urinary aldosterone')." | 3.67 | 21-Deoxytetrahydroaldosterone excretion in primary hyperaldosteronism. ( Abdelhamid, S; Lewicka, S; Vecsei, P; Winter, J, 1985) |
"To investigate the regulation of arterial pressure and vasoactive hormones in hypothyroidism associated with hypertension, we measured intra-arterial pressure and hourly venous hormones (renin, angiotensin II, aldosterone, catecholamines and cortisol) for 24 hours in five hypertensive patients with primary hypothyroidism before commencing treatment, and again after three to six months of thyroxine replacement therapy." | 3.67 | Hypertension in hypothyroidism: arterial pressure and hormone relationships. ( Brownlie, BE; Espiner, EA; Ikram, H; Nicholls, MG; Richards, AM; Turner, JG, 1985) |
"Sixteen patients (11 M, 5 F), median age 41 years, with essential hypertension insufficiently controlled on hydrochlorothiazide 75 mg/day (DBP greater than or equal to 100 mmHg) were investigated." | 3.66 | Angiotensin II blockade during combined thiazide-beta-blocker treatment. ( Christensen, NJ; Giese, J; Ibsen, H; Leth, A; McNair, A, 1980) |
"0 mg/kg prizidilol HCl, an antihypertensive with vasodilator and beta-adrenoceptor blocking actions, were given to 12 patients with primary hypertension on separate days." | 3.66 | Prizidilol, an antihypertensive with precapillary vasodilator and beta-adrenoceptor blocking actions, in primary hypertension. ( Karlberg, BE; Larsson, R; Norlander, B; Wirsén, A, 1981) |
"The antihypertensive effect of captopril was tested on 19 patients with essential hypertension, WHO grade I or II." | 3.66 | [Captopril in the treatment of essential hypertension (author's transl)]. ( Braun, B; Klaus, D; Lederle, RM, 1980) |
"Hemodynamic responses and behaviors of the renin-angiotensin-aldosterone system to a single administration of captopril (50 mg) were studied in 16 hypertensive patients (essential hypertension, n = 10; renovascular hypertension, n = 3; primary aldosteronism, n = 2; Cushing's syndrome, n = 1)." | 3.66 | Effects of a single administration of captopril on hemodynamics and serum angiotensin converting enzyme activity, plasma renin activity and plasma aldosterone concentration in hypertensive patients. ( Hashimoto, H; Hiwada, K; Kokubu, T, 1981) |
" The plasma aldosterone responses to exogenous angiotensin II and adrenocorticotropic hormone (ACTH) were studied before and after 1 month of propranolol therapy (120-240 mg/day) in eight patients with essential hypertension." | 3.66 | Effect of propranolol therapy on aldosterone responses to angiotensin II and adrenocorticotropic hormone in essential hypertension. ( Fittingoff, DB; Golub, MS; Tuck, ML, 1981) |
" Blood pressure was normal during treatment with spironolactone and during pregnancy, when the action of aldosterone and other similar steroids was presumably blocked by an increased production of progesterone; this suggests that the hypertension is dependent upon sodium-retaining steroids such as aldosterone." | 3.66 | Overproduction of sodium-retaining steroids by the zona glomerulosa is adrenocorticotropin-dependent and mediates hypertension in dexamethasone-suppressible aldosteronism. ( Bartter, FC; Gill, JR, 1981) |
"Captopril was given alone and in combination with diuretics to 49 patients with hypertension for 1 to 12 mol Within 2 mo blood pressure reduction correlated with pretreatment plasma renin activity and response to the infusion of angiotensin II antagonist, but these effects were not present at 4 mo." | 3.66 | Hormonal responses to long-term converting enzyme inhibition in hypertensive patients. ( Hata, T; Kumahara, Y; Maruyama, A; Mikami, H; Naka, T; Nakamaru, M; Ogihara, T; Ohde, H, 1981) |
"30% of patients with essential hypertension have a decreased adrenal response to angiotensin II (A II) on a low but not a high sodium intake." | 3.66 | Decreased adrenal responsiveness to angiotensin II: a defect present in spontaneously hypertensive rats. A possible model of human essential hypertension. ( Braley, LM; Menachery, A; Williams, GH, 1982) |
"To study effects on pituitary-adrenocortical activity of a sustained block of angiotensin II formation, six 'drug-resistant' patients with essential hypertension were studied before and during treatment with an inhibitor of the angiotensin-converting enzyme (Captopril, SQ 14,225)." | 3.66 | Pituitary - adrenocortical function in patients during treatment with the angiotensin-converting enzyme inhibitor captopril. ( Angeli, A; Bisbocci, D; Lavezzaro, GC; Orlandi, F; Paccotti, P; Tabasso, R; Tamagnone, C, 1981) |
"The humoral and hemodynamic effects of converting enzyme inhibition captopril are presented in two patients with primary hyperaldosteronism (PHA)." | 3.66 | Converting enzyme inhibition with captopril in patients with primary hyperaldosteronism. ( Demers, LM; Harrison, TS; Hayes, AH; Luderer, JR, 1982) |
"Captopril was given to 15 unselected patients with essential hypertension (WHO II) at a dose range of 300 to 600 mg/day." | 3.66 | Angiotensin-converting enzyme inhibition, catecholamines and hemodynamics in essential hypertension. ( Agabiti-Rosei, E; Alicandri, CL; Beschi, M; Boni, E; Castellano, M; Fariello, R; Moniti, E; Muiesan, G; Muiesan, L; Romanelli, G; Zanielli, A, 1982) |
"To compare the hemodynamic and humoral effects of increasing doses of captopril, blood pressure, heart rate, plasma renin activity, plasma aldosterone and angiotensin-converting enzyme activity were measured in 10 patients with mild uncomplicated essential hypertension before and after captopril given in an increasing dose of 25, 50 and 100 mg twice a day, with each dose given for 3 days." | 3.66 | Humoral and hemodynamic effects of increasing doses of captopril in patients with essential hypertension. ( Abdel-Haq, B; Magagna, A; Pedrinelli, R; Salvetti, A; Sassano, P, 1982) |
"Ten milligrams nifedipine was administered orally to young and old persons with or without hypertension, and the acute effects of nifedipine on the renin-angiotensin-aldosterone system were studied one half to 3 hours later." | 3.66 | Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension. ( Hiramatsu, K; Kubota, T; Yamada, T; Yamagishi, F, 1982) |
"The acute blood pressure response to the angiotensin converting enzyme inhibitor, captopril, was used to measure participation of the renin-angiotensin system in treatment-resistant hypertension." | 3.66 | Participation of the renin system in treatment-resistant hypertension as measured by acute blockade of the angiotensin converting enzyme. ( Chen, TC; Drayer, JI; Priest, RT; Weber, MA, 1982) |
"Four major volume hormones may be involved in human hypertension: aldosterone, arginine vasopressin, inhibitors of NA+/K+ ATPase activity, and the natriuretic factor from specific granules of atrial cardiocytes." | 3.66 | Volume hormones and blood pressure. ( Genest, J, 1983) |
"In order to clarify the influence of food on the clinical effect of angiotensin I converting enzyme inhibitor (SQ 14,225, captopril), 25 mg of the drug was administered to patients with hypertension using in a two-way crossover study design." | 3.66 | Influence of food on the clinical effect of angiotensin I converting enzyme inhibitor (SQ 14,225). ( Hatano, M; Honda, M; Izumi, Y; Kawahara, Y, 1983) |
"Infusion of angiotensin II into a patient with dexamethasone-suppressible hyperaldosteronism caused a brisk increase in plasma aldosterone concentration." | 3.66 | 10. Hypertension. A comparison of the effects of angiotensin II infusion and variations in salt intake on plasma aldosterone levels in normal subjects, patients with essential hypertension and patients with hyperaldosteronism. ( Brown, JJ; Fraser, R; Lever, AF; Robertson, JI; Usherwood, T; Zoccali, C, 1983) |
"To investigate the role of the renin-angiotensin-aldosterone system in hypertension due to coarctation of the aorta (COA), upright mean arterial pressure (MAP), plasma renin activity (PRA) and plasma aldosterone (Aldo) were determined before and 90 minutes after a single oral dose of captopril (25 mg) in eight patients with COA and in fourteen with essential hypertension (EH)." | 3.66 | Effect of captopril on blood pressure and on the renin-angiotensin-aldosterone system in coarctation of the aorta. ( Fallo, F; Mantero, F; Maragno, I; Merola, P, 1983) |
"The effects of endralazine, administered intravenously, on blood pressure, heart rate, forearm blood flow, plasma renin activity, aldosterone, adrenaline and noradrenaline were studied in five patients with essential hypertension." | 3.66 | Effects of intravenous endralazine in essential hypertension. ( Hoffmann, JJ; Thien, T; van T'Laar, A, 1983) |
"The effects of penbutolol 20-30 mg twice daily and of metoprolol 50-150 mg three times daily were studied in five and nine patients, respectively, with moderate hypertension." | 3.66 | Effects of penbutolol and metoprolol on blood pressure, plasma catecholamines and renin activity in hypertensive patients. ( Dymling, JF; Hansson, BG; Hökfelt, B; Manhem, P, 1983) |
"Plasma aldosterone levels were measured during two tests of inhibition in 31 hypertensive patients (13 essential hypertension, 6 bilateral adrenal hyperplasia and 12 documented Conn adenomas) on normal salt diets after withdrawal of all therapy: 1--before and after intravenous infusion of 2 I normal saline in two hours; 2--before and three hours after administration of 1 mg/kg of Captopril." | 3.66 | [A new diagnostic test for primary tumoral hyperaldosteronism]. ( Corvol, P; Dufloux, MA; Ménard, J; Plouin, PF; Sassano, P; Thibonnier, M, 1983) |
"Nine patients with refractory hypertension, ranging in age from 6 to 18 years, were given captopril." | 3.66 | Effect of captopril on the renin-angiotensin system in hypertensive children. ( Chesney, RW; Friedman, AL, 1983) |
"Plasma renin activity (PRA), plasma aldosterone (PA), blood uric acid (BUA), plasma concentrations of catecholamines (Pcat) and plasma volume (PV) were measured simultaneously in 24 patients with pregnancy-induced hypertension (PIH)." | 3.66 | Plasma renin activity, blood uric acid and plasma volume in pregnancy-induced hypertension. ( Boulanger, JC; Carayon, A; Coevoet, B; Comoy, E; de Fremont, JF; Demory, JE; Desailly, I; Fievet, P; Pleskov, L; Verhoest, P, 1983) |
"In order to clarify the role of the kallikrein-kinin system in the hypotensive mechanisms of converting-enzyme inhibition, captopril was administered in a single oral dose of 50 mg to 17 hypertensive patients, of whom 14 had essential hypertension, one had chronic renal failure, one had primary aldosteronism, and one had glucocorticoid responsive hyperaldosteronism." | 3.66 | [Acute antihypertensive effect of captopril in hypertensive patients: with special reference to kallikrein-kinin system]. ( Fukuchi, S; Gotoh, M; Haruyama, K; Hashimoto, S; Matsui, J; Mizuno, K; Toki, T, 1983) |
" The effects of 3 wk of treatment with two selective beta 1 blockers, metoprolol and atenolol, were observed in 54 patients with mild or moderate essential hypertension." | 3.66 | Predictability of antihypertensive efficacy of selective beta 1 blockers. ( Condorelli, M; Cuocolo, A; De Luca, N; Ricciardelli, B; Trimarco, B; Veniero, AM; Volpe, M, 1983) |
"This study examines the influence of bromocriptine, a dopamine agonist, on circadian secretory patterns of plasma 18-hydroxycorticosterone (18-OHB) and cortisol in essential hypertension." | 3.66 | Effects of bromocriptine on the circadian rhythm of 18-hydroxycorticosterone and cortisol secretion in essential hypertensives. ( Beck, FW; Sowers, JR; Stern, N; Tuck, ML, 1983) |
"To evaluate the therapeutic efficacy of oral angiotensin-converting enzyme inhibition with low-dose (average 30 mg/day) captopril in diuretic-resistant hypertension, its long-term cardiocirculatory action was determined by dye-dilution method and venous-occlusion forearm plethysmography in 11 uncontrolled patients taking a thiazide diuretic." | 3.66 | Hemodynamic and endocrine changes associated with captopril in diuretic-resistant hypertensive patients. ( Ando, K; Fujita, T; Noda, H; Sato, Y; Yamashita, K; Yamashita, N, 1982) |
"The response of plasma renin activity (PRA), plasma aldosterone, 18-hydroxycorticosterone (18-OH-B), 18-hydroxydeoxycorticosterone (18-OH-DOC) and corticosterone to furosemide were compared in 20 normal control subjects, 16 patients with normal-renin essential hypertension (NREH) and 12 patients with low-renin essential hypertension (LREH)." | 3.66 | Rapid increase of mineralocorticoids after furosemide in low-renin essential hypertension: evidence for 18-hydroxycorticosterone to be a better marker than aldosterone. ( Thayil, G; Weber, PC; Witzgall, H, 1982) |
"1 The long-term effects of the oral angiotensin-converting enzyme inhibitor captopril with the addition of a diuretic (chlorthalidone) were examined in 16 patients with moderate or grave hypertension." | 3.66 | Long-term captopril treatment in moderate to severe hypertension. ( Aguglia, F; Balsano, F; De Mattia, G; Ficara, C; Santucci, A, 1982) |
"The role of the renin-aldosterone axis in mediating responses to antihypertensive treatment was examined in patients with essential hypertension treated with propranolol (n=50) or chlorthalidone (n=50)." | 3.66 | The role of aldosterone in the response to treatment of primary hypertension. ( Drayer, JI; Laragh, JH; Purdy, RE; Weber, MA, 1982) |
"Paradoxical glucose-induced hyperkalemia (GIH) was elicited exclusively in the upright position during captopril treatment in four hypertensive patients (Group 3) without impaired glucose tolerance in three." | 3.66 | Glucose-induced hyperkalemia developing in the upright position in captopril-treated hypertensives. ( Bános, C; Csabuda, M; Gercsák, G; Molnár, Z; Pató, E; Radó, JP, 1982) |
"The interrelationship between PRA, urinary aldosterone excretion, and blood pressure was studied in 11 patients with essential hypertension while receiving a diuretic (1st week) and subsequently a diuretic + oxprenolol (2nd week)." | 3.66 | The renin-angiotensin-aldosterone system and blood pressure during oxprenolol treatment in hypertensive patients pretreated with diuretics. ( Pedrinelli, R; Salvetti, A; Simonini, N, 1982) |
"5 mg and 25 mg) of angiotensin I converting enzyme inhibitor (SQ 14,255, captopril) were administered to 8 patients with essential hypertension on a three-crossover study design, and the time course of mean blood pressure (MBP), plasma renin activity (PRA), plasma angiotensin converting enzyme activity (ACE-A), plasma cortisol (PC) and plasma aldosterone (PA) were determined following administration of the drug." | 3.66 | Effects of various doses of captopril on plasma aldosterone concentrations in patients with essential hypertension. ( Hatano, M; Honda, M; Izumi, Y, 1982) |
"The studies were designed to explore the effect of the converting enzyme inhibitor captopril on the activity of the sympathetic nervous system during basal conditions and following graded physical exercise in patients with essential hypertension." | 3.66 | The effect of captopril on catecholamines, renin activity, angiotensin II and aldosterone in plasma during physical exercise in hypertensive patients. ( Bramnert, M; Hökfelt, B; Hulthén, UL; Manhem, P, 1981) |
"Plasma concentrations and urinary excretion rate of vasopressin (VP) were examined in ten cases of severe hypertension before and during short-term treatment by Captopril (SQ 14225)." | 3.66 | Reduction of plasma and urinary vasopressin during treatment of severe hypertension by captopril. ( Aldiger, JC; Corvol, P; Menard, J; Milliez, P; Soto, ME; Thibonnier, M, 1981) |
"We investigated changes in the renin-angiotensin-aldosterone system in seven patients with essential hypertension during treatment with captopril (SQ 14225) (300 to 450 mg/day) for 12 months." | 3.66 | Captopril in the long-term treatment of essential hypertension: changes in the renin-angiotensin-aldosterone system. ( Hayduk, K; Liebau, G; Riegger, GA; Steilner, H, 1982) |
"Hypertension-prone, male, spontaneously hypertensive rats (SHR; n = 60) and normotensive, male, Sprague-Dawley rats (S-D; n = 60) were exposed to the relatively innocuous stimulus of heat and ether when they were 40 days of age, just before the usual onset of high blood pressure in SHR." | 3.66 | Hypersensitivity of spontaneously hypertensive rats to heat and ether before the onset of high blood pressure. ( McMurtry, JP; Wexler, BC, 1983) |
"Plasma volume (PV), extracellular fluid volume (ECV) serum electrolytes, renin and aldosterone were measured before and after 1 week and 4 months of hydrochlorothiazide (HCT) treatment, 50 mg twice daily, in nine male patients with uncomplicated essential hypertension." | 3.66 | Body fluid volumes and the response of renin and aldosterone to short- and long-term thiazide therapy of essential hypertension. ( Schalekamp, MA; van Brummelen, P, 1980) |
"Twenty-one patients with essential hypertension received a constant infusion of angiotensin II and des-aspartyl1-angiotensin II for 45 min on 2 consecutive days during normal sodium intake." | 3.66 | A comparative study on (des-aspartyl1)-angiotensin II and angiotensin II in patients with essential hypertension. ( Fukuchi, S; Mizuno, K; Yamazaki, M, 1980) |
"Captopril was given for treatment of hypertension alone or in combination with diuretics to 32 patients for 1- to 4-mo periods." | 3.66 | Long-term effects of captopril in hypertension. ( Hata, T; Iwanaga, K; Kumahara, Y; Maruyama, A; Mikami, H; Naka, T; Nakamaru, M; Ogihara, T, 1980) |
"The effect of the converting enzyme inhibitor captopril on arterial pressure, the components of the renin-angiotensin-aldosterone system, and body sodium and potassium content was studied in eight hypertensive patients with renal artery stenosis and, in conjunction with diuretics, in seven patients with hypertension unresponsive to previous treatment." | 3.66 | Captopril in clinical hypertension. Changes in components of renin-angiotensin system and in body composition in relation to fall in blood pressure with a note on measurement of angiotensin II during converting enzyme inhibition. ( Atkinson, AB; Brown, JJ; Davies, DL; Fraser, R; Kelly, P; Leckie, B; Lever, AF; Morton, JJ; Robertson, JI, 1980) |
"Arterial blood pressure and plasma catecholamines, renin activity and aldosterone concentration in 12 patients with severe essential hypertension were studied before and after combined alpha- and beta- adrenoceptor blockade induced by oral labetalol treatment for 2 months." | 3.66 | Plasma catecholamines, renin and aldosterone during combined alpha- and beta- adrenoceptor blockade in patients with severe arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Pedersen, A; Pedersen, EB; Pedersen, G, 1980) |
"A simultaneous analysis of the interrelationships between mean blood pressure (MBP), plasma catecholamines, plasma renin activity (PRA) and aldosterone, exchangeable body sodium, and blood volume was carried out before and after acute and chronic administration of clonidine in 15 patients with essential hypertension, in order to further elucidate the mechanism(s) of action of this drug." | 3.66 | Role of sympathetic nerve inhibition and body sodium-volume state in the antihypertensive action of clonidine in essential hypertension. ( Campese, VM; Massry, SG; Romoff, M; Telfer, N; Weidmann, P, 1980) |
"A case of severe hypertension resistant to multiple drug therapy was controlled with minoxidil, captopril, and propranolol hydrochloride after treatment with these drugs alone or in other combinations had failed." | 3.66 | Interaction of minoxidil and captopril in the treatment of refractory hypertension. ( Matson, JR; Norby, LH; Robillard, JE, 1981) |
"Eight patients with essential hypertension, WHO grade I-III, were studied under standardized conditions in a metabolic ward, before and after 8-20 weeks of treatment with clonidine in a maintenance dose of 300-600 micrograms/24 h." | 3.66 | Prolonged clonidine treatment: catecholamines, renin activity and aldosterone following exercise in hypertensives. ( Hökfelt, B; Manhem, P, 1981) |
"The plasma aldosterone (PA) response to sodium restriction (25 mEq daily for 4 days) and to graded infusions of angiotensin II (AII, 2, 4 and 8 ng/kg/min each for 30 min) during a low-sodium intake were studied in 15 elderly subjects with mild essential hypertension versus 10 elderly normotensive subjects." | 3.66 | Plasma aldosterone response to angiotensin II in sodium-restricted elderly subjects with essential hypertension. ( Kigoshi, T; Miyamoto, M; Morimoto, S; Morise, T; Takeda, R; Takimoto, H; Uchida, K, 1981) |
"The role of the renin-angiotensin system in the development of hypertension was studied by infusing an angiotensin II analog, 1-Sar, 8-Ile angiotensin II, in women with toxemia and women on estrogen-containing oral contraceptives or estrogen treatment." | 3.66 | Effects of angiotensin II analog on blood pressure, renin and aldosterone in women on oral contraceptives and toxemia. ( Kondo, K; Nagahama, S; Nakamura, R; Saruta, T; Suzuki, H, 1981) |
"The effect of 5 to 9 days of metyrapone administration (400 mg/m2 every 4 h) on aldosterone, deoxycorticosterone, plasma renin activity, electrolyte balance, and blood pressure was investigated in 2 normotensive siblings (one of whom showed limited ACTH reserve), in 3 patients with hypertension and dexamethasone-suppressible hyperaldosteronism, and in a hypertensive patient with primary hyperaldosteronism due to bilateral adrenal hyperplasia." | 3.66 | Mineralocorticoid and metabolic response to metyrapone on normotensive children and children with dexamethasone-suppressible and primary hyperaldosteronism. ( Levine, LS; New, MI; Sonino, N, 1981) |
" Captopril, an orally active angiotensin converting enzyme inhibitor, was abruptly withdrawn from the antihypertensive regimen of 6 patients (5 males; aged 31 to 58) with moderate to severe hypertension." | 3.66 | Captopril withdrawal after chronic therapy. ( Ferguson, RK; Green, PJ; Koffer, H; McElwain, GE; Vlasses, PH, 1981) |
"The time courses of mean blood pressure (MBP), plasma renin activity (PRA), plasma aldosterone (PA), serum prostaglandin E (PGE), serum angiotensin I converting enzyme (ACE), and blood levels of angiotensin I converting enzyme inhibitor (SQ 14,225) (captopril) were studied in 6 patients with essential hypertension (5 men and 1 woman, aged 44 +/- 5." | 3.66 | Relationship between blood pressure and blood levels of angiotensin I converting enzyme inhibitor (SQ 14,225). ( Hatano, M; Honda, M; Izumi, Y; Kawahara, Y, 1981) |
"Antihypertensive effect of an orally active angiotensin I-Converting enzyme inhibitor, SQ 14225 (Captopril) was assessed in 18 hypertensive patients, of whom 13 had essential hypertension, 2 had malignant hypertension, 2 had hypertension associated with chronic renal failure, and 1 had renovascular hypertension." | 3.66 | Antihypertensive effect of the oral angiotensin I-converting enzyme inhibitor in long-term treatment of hypertensive patients. ( Fukuchi, S; Gotoh, M; Matsui, J; Mizuno, K, 1981) |
"Trimazosin was given for periods of at least 6 mo to 25 patients with mild to moderate essential hypertension." | 3.66 | A vasodilator that avoids renin stimulation and fluid retention: antihypertensive treatment with trimazosin. ( Aronow, WS; Brewer, DD; Drayer, JI; Lipson, JL; Ricci, BA; Weber, MA, 1982) |
"The hypertensiogenic effects of 19-hydroxyandrostenedione (19-OH-A-dione) reported previously to be an amplifier of the action of aldosterone were evaluated using the same experimental procedures as for DOCA-salt hypertension in rats." | 3.66 | 19-hydroxyandrostenedione as a new hypertensinogenic agent. ( Sekihara, H, 1982) |
"Plasma aldosterone (PA) responses to sodium restriction (25 mEq sodium/day for 4 days) and to graded angiotensin II (AII) infusions (2, 4 and 8 ng/kg/min each for 30 min) during a low sodium intake were studied in 14 subjects with low renin essential hypertension (LREH) versus 16 normotensive subjects." | 3.66 | Aldosterone responsiveness to angiotensin II after sodium restriction in subjects with low renin essential hypertension. ( Fujimura, A; Hashiba, T; Honjo, A; Kigoshi, T; Morimoto, S; Takeda, R; Uchida, K, 1982) |
"For distinguishing primary aldosteronism from essential hypertension, we use simple direct radioimmunoassays for "aldosterone" (aldosterone and other materials that react with the antibody to aldosterone) and "18-hydroxycorticosterone" (similarly) in unprocessed urine." | 3.66 | Direct radioimmunoassays for "aldosterone" and "18-hydroxycorticosterone" in unprocessed urine, and their use in screening to distinguish primary aldosteronism from hypertension. ( Abdelhamid, S; Benraad, TJ; Haack, D; Hofman, J; Lichtwald, K; Vecsei, P, 1982) |
"Simultaneous measurement of the 0800-hr plasma concentrations of deoxycorticosterone (DOC), corticosterone (B), 18-hydroxycorticosterone (18-OHB), aldosterone, 18-hydroxydeoxycorticosterone (18-OHDOC) and cortisol (F) in four types of primary aldosteronism provides evidence for primary adrenal disease." | 3.66 | The mineralocorticoid hormone pathways in hypertension with hyperaldosteronism. ( Biglieri, EG; Brust, N; Chang, B; Hirai, J; Kater, CE, 1982) |
"The most abundant substance in the urinary free steroid fraction of patients with primary aldosteronism has been identified as 18-hydroxycortisol." | 3.66 | Hypersecretion of a new corticosteroid, 18-hydroxycortisol in two types of adrenocortical hypertension. ( Chu, MD; Ulick, S, 1982) |
"In view of recent evidence that spironolactone may inhibit synthesis of corticosteroids by a direct effect on the adrenal cortex, adrenocortical function was studied in eight patients with essential hypertension who had been treated with spironolactone from 3 months to 14 years." | 3.66 | Long term spironolactone and the adrenal cortex in essential hypertension. ( Gorchein, A; Horth, CE; James, VH; Lewis, PS; May, CN, 1980) |
"Plasma concentrations of angiotensin II (AII), aldosterone, 18-hydroxycorticosterone and cortisol were measured in seven patients with benign essential hypertension and in seven age-matched control subjects before, and at frequent intervals for 2 h after the intravenous injection of frusemide (40 mg)." | 3.66 | Increased 18-hydroxycorticosterone responses to frusemide in essential hypertension. ( Fraser, R; Mason, PA; Semple, PF, 1980) |
"Sequential changes in plasma renin activity and urinary aldosterone and noradrenaline were assessed in eight patients with severe hypertension after minoxidil had been added to their treatment." | 3.66 | Need for beta-blockade in hypertension reduced with long-term minoxidil. ( Brunner, HR; Ferguson, RK; Gavras, H; Jaeger, P; Jequier, E; Turini, G, 1978) |
"In order to investigate the role of 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) in essential hypertension (EH), the responses of plasma 17-OH-DOC to 7 stimulation tests (furosemide test, adrenal suppression test, angiotensin II infusion test, adrenal stimulation test, metopirone test, saline infusion test and potassium chloride infusion test) and the circadian rhythm were investigated in 18 patients with essential hypertension (low renin group: 8, and normal renin group: 10)." | 3.66 | Plasma levels of 18-hydroxy-11-deoxycorticosterone in essential hypertension. ( Den, K; Hatano, M; Honda, M; Izumi, Y; Kanbegawa, A; Oguri, K; Shiratsuchi, T; Tsuchiya, M; Ueda, Y, 1978) |
"To determine the mechanism underlying altered adrenal responsiveness in patients with essential hypertension, the renin-angiotensin-aldosterone axis was assessed in normotensive and hypertensive subjects using three pharmacological probes: SQ 20881, a converting enzyme inhibitor; saralasin, a competitive angiotensin antagonist with prominent agonist properties; and angiotensin itself." | 3.66 | The adrenal receptor for angiotensin II is altered in essential hypertension. ( Dluhy, RG; Hollenberg, NK; Moore, TJ; Swartz, SL; Williams, GH, 1979) |
") before and during treatment with spironolactone (Sp, 75--100 mg/day) for at least 8 months was studied in 11 patients with essential hypertension." | 3.66 | Reduced response of plasma aldosterone to acute ACTH stimulation during long-term treatment with spironolactone in essential hypertension. ( Kim, KS; Miyamori, I; Miyamoto, M; Morimoto, S; Takeda, R; Uchida, K, 1979) |
" In 20 subjects with uncomplicated essential hypertension, 10 of whom were on propranolol treatment, several blood samples were drawn simultaneously from the renal artery and vein after angiographic studies." | 3.66 | Noradrenaline secretion by the human kidney. ( Birkenhäger, WH; de Leeuw, PW; Falke, HE; Punt, R, 1978) |
"To examine the involvement of renin-angiotensin-aldosterone system in the etiology of oral contraceptive induced hypertension, normal women (Group I), normotensive (Group II) and hypertensive (Group III) women taking Ovulen (R) were infused with a competitive angiotensin II (AII) antagonist, [1-sarcosine, 8-isoleucine] angiotensin II." | 3.66 | Effects of an angiotensin II antagonist; [sarcosine 1, isoleucine 8] angiotensin II, on blood pressure, plasma renin activity and plasma aldosterone concentration in hypertensive and normotensive subjects taking oral contraceptives. ( Hata, T; Kumahara, Y; Maruyama, A; Mikami, H; Nakamaru, M; Ogihara, T, 1979) |
"We substituted minoxidil for dihydralazine in the treatment of 10 patients with refractory hypertension." | 3.66 | [Effects of minoxidil on blood pressure and plasma volume in refractory hypertension (author's transl)]. ( Alhenc-Gelas, F; Ménard, J; Morgado Vital, A; Plouin, PF, 1979) |
" Blood pressure, systemic haemodynamics, plasma volume, renin and aldosterone were measured during placebo treatment and after 1, 4 and 12 weeks of hydrochlorothiazide in 13 patients with uncomplicated essential hypertension." | 3.66 | Haemodynamics during long-term thiazide treatment in essential hypertension: differences between responders and non-responders. ( Man in't Veld, A; Schalekamp, MA; Van Brummelen, P, 1979) |
"The plasma aldosterone response to infused angiotensin II was determined in normal controls and in patients with normal renin and with low renin essential hypertension." | 3.66 | Enhanced adrenal responsiveness to angiotensin II in patients with low renin essential hypertension. ( Adlin, VE; Channick, BJ; Kanefsky, TM; Marks, AD; Marks, DB, 1979) |
"To determine if the abnormally large increases in levels of plasma aldosterone which occur during infusion of angiotensin II in some patients with essential hypertension are due to abnormal decreases in the metabolic clearance of aldosterone, we measured clearances of aldosterone before and during infusion of angiotensin II in 12 patients with essential hypertension and in 10 normal subjects." | 3.66 | The metabolic clearance of aldosterone decreases similarly during infusion of angiotensin II in patients with essential hypertension and in normal subjects. ( Brown, RD; Wisgerhof, M, 1979) |
"In essential hypertension mean basal (supine) and stimulated plasma renin activity (2 h upright posture + 40 mg furosemide intraveneously) decreased progressively with age." | 3.66 | Age- and sex-related differences in plasma aldosterone in essential hypertension. Relationship to plasma renin activity. ( Alasso, I; Glänzer, K; Vetter, H; Vetter, W, 1979) |
"Plasma concentrations of angiotensin II (AII) were studied in 36 patients with primary (essential) hypertension and 15 normotensive control subjects during basal (1 h supine rest), upright and frusemide-stimulated (80 mg orally) conditions." | 3.66 | Angiotensin II in primary hypertension, relationship to plasma renin activity, aldosterone and urinary electrolytes. ( Karlberg, BE; Tolagen, K, 1979) |
"Adrenal responsiveness to angiotensin II (AII) and the diastolic blood pressure responses to saralasin were studied in 19 patients with high renin essential hypertension (HREH) on a 10-meq Na(+)/100 meq K(+) diet." | 3.66 | Abnormal adrenal responsiveness and angiotensin II dependency in high renin essential hypertension. ( Bavli, SZ; Dluhy, RG; Hollenberg, NK; Leung, FK; Moore, TJ; Solomon, HS; Williams, GH, 1979) |
"3%) the normal, aldosterone-18-glucuronide concentration was clinically misleading, but increased free aldosterone and/or tetrahydroaldosterone values suggested the presence of hyperaldosteronism, which in many of these cases was confirmed by elevated excretion of the possible major aldosterone precursor 18-hydroxycorticosterone (18-OH-B)." | 3.66 | Dissociation in the excretion of different aldosterone metabolites and unmetabolized ('free') aldosterone in hypertension. ( Abdelhamid, S; Fiegel, P; Gless, KH; Haack, D; Lichtwald, K; Vecsei, P; Walb, D, 1979) |
" To characterize the renin-angiotensin-aldosterone system in elderly hypertensive patients, an angiotensin II antagonist, [Sar1,Ile8]angiotensin II, was infused into individuals 60 years old and older with and without hypertension." | 3.66 | Studies on the renin-angiotensin-aldosterone system in elderly hypertensive patients with an angiotensin II antagonist. ( Hata, T; Kumahara, Y; Mandai, T; Maruyama, A; Mikami, H; Nakamaru, M; Ogihara, T, 1979) |
"Arterial blood pressure and plasma catecholamines, renin activity and aldosterone concentration in 12 patients with severe essential hypertension were studied before and after combined alpha- and beta-adrenergic receptor blockage induced by oral labetalol treatment for 2 months." | 3.66 | Effect of oral labetalol on plasma catecholamines, renin and aldosterone in patients with severe arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Pedersen, A; Pedersen, EB; Pedersen, G, 1979) |
"Succinamyl-arg-val-tyr-val-his-pro-phenylglycine acetate (succinamyl1-val5-phenylglycine acetate3-A II), an analogue of angiotensin II, has a pressor effect upon patients suffering from primary and secondary hypertension regardless of prevailing plasma renin concentration." | 3.66 | Effect of an angiotensin II analogue upon blood pressure, plasma renin concentration and plasma aldosterone in hypertensive patients. ( Vierhapper, H; Waldhäusl, W, 1979) |
"The effect of furosemide on urinary kallikrein excretion was studied in 10 patients with essential hypertension and 9 normal volunteer subjects." | 3.66 | Effect of furosemide on urinary kallikrein excretion in patients with essential hypertension. ( Abe, K; Chiba, S; Irokawa, N; Ito, T; Kusaka, T; Miyazaki, S; Ritz, K; Saito, K; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K, 1978) |
"Seventy-nine patients with essential hypertension were evaluated for peripheral renin activity in response to injection of 60 mg of furosemide and to upright posture." | 3.66 | The multiple factors affecting plasma renin activity in essential hypertension. ( Corder, CN; McDonald, RH; Shuman, J; Vagnucci, AH, 1978) |
"Studies were undertaken to determine if the dissociation of aldosterone and plasma renin activity in low-renin essential hypertension is due to altered adrenal responsiveness to angiotensin II." | 3.66 | Increased adrenal sensitivity to angiotensin II in low-renin essential hypertension. ( Brown, RD; Wisgerhof, M, 1978) |
"To determine the influence of dietary sodium intake on the effects of hydrochlorothiazide (HCT) on blood pressure (BP), serum electrolytes, renin and aldosterone, nine male patients with uncomplicated essential hypertension were studied during the following therapeutic regimes: 1) sodium restriction alone (50 mmol/day), 2) sodium restriction combined with HCT (50 MG TWICE DAILY), 3) HCT alone, and 4) sodium restriction combined with HCT." | 3.66 | Influence of sodium intake on hydrochlorothiazide-induced changes in blood pressure, serum electrolytes, renin and aldosterone in essential hypertension. ( de Graeff, J; Schalekamp, M; van Brummelen, P, 1978) |
" in 1975 revealed that the antihypertensive and natriuretic effects of furosemide were markedly blunted or abrogated by indomethacin in both normotensive and hypertensive man, it has been postulated that the ameliorative effects of furosemide in human essential hypertension might be mediated by release of intrarenal prostaglandins." | 3.66 | Antihypertensive effect of volume depletion: interrelation with renal prostaglandins. ( Attallah, A; Braselton, WE; Düsing, R; Lee, JB, 1978) |
"Eleven patients with hypertension secondary to renal disease were treated with hydrochlorothiazide or furosemide plus other drugs to normalize blood pressure." | 3.66 | Use of diuretics in treatment of hypertension secondary to renal disease. ( Bank, N; Lief, PD; Piczon, O, 1978) |
"In order to evaluate the relationship between aldosterone status and the blood pressure-lowering effect of spironolactone, 38 patients with essential hypertension were treated with spironolactone (400 mg/day) during one week in hospital on a rigidly sodium-restricted diet." | 3.66 | Role of aldosterone in the antihypertensive effect of spironolactone in essential hypertension. ( Benraad, H; Benraad, T; Drayer, J; Hoefnagels, W; Kloppenborg, P, 1978) |
"In 34 patients saralasin was infused after variable degrees of sodium depletion in order to differentiate between essential and renin-induced hypertension." | 3.66 | [Saralasin-induced changes of blood pressure, renin and aldosterone in essential and renal hypertension (author's transl)]. ( Beyer, J; Hayduk, K; Liebau, G; Steiner, B, 1978) |
"Minoxidil-induced sequential changes in plasma renin activity, urinary aldosterone and norepinephrine excretion were assessed in 11 patients with severe hypertension receiving propranolol or oxprenolol, chlorthalidone and spironolactone." | 3.66 | [Long-term minoxidil therapy: renin, aldosterone, noradrenaline and the need for beta blockers]. ( Brunner, HR; Ferguson, RK; Gavras, H; Jaeger, P; Jéquier, E; Turini, GA, 1978) |
"The blood pressure response to the angiotensin II analog 1-sar-8-ala-angiotensin II, or saralasin, was studied in five patients with clinical and laboratory evidence of Cushing's syndrome." | 3.66 | Evidence for an angiotensinogenic mechanism of the hypertension of Cushing's syndrome. ( Anderson, GH; Dalakos, TG; Elias, AN; Schroeder, ET; Streeten, DH, 1978) |
"The effect of indomethacin on plasma renin activity (PRA), urinary aldosterone, 17 OH ketogenic steroids and plasma cortisol was studied in twenty-three patients with essential hypertension and compared in eleven patients to oxprenolol effect by 2 x 2 factorial trial." | 3.66 | The effect of indomethacin on plasma renin activity and urinary aldosterone of patients with essential hypertension. ( Arzilli, F; Cavasinni, L; Pedrinelli, R; Poli, L; Salvetti, A; Sassano, P, 1978) |
"A previously unidentified mineralocorticoid, 16beta-hydroxydehydroepiandrosterone (16beta OH-DHEA) has recently been isolated from urine extracts of patients with low-renin hypertension and reported to possess one-fortieth the mineralocorticoid potency of aldosterone by bioassay." | 3.65 | Interaction of 16beta-hydroxydehydroepiandrosterone with renal mineralocorticoid receptors. ( Gomez-Sanchez, C; Higgins, JR; Holland, OB; Kaplan, NM; Kem, DC; Wambach, G, 1977) |
"Adrenal and vascular responsiveness to graded doses of angiotensin II (A II) were recorded for seven normal subjects and 12 patients with essential hypertension while in balance on an intake of 200 mEq sodium/100 mEq potassium." | 3.65 | Enhanced aldosterone response to angiotensin II in human hypertension. ( Dluhy, RG; Kisch, ES; Williams, GH, 1976) |
"Plasma concentrations of progesterone (P), deoxycorticosterone (DOC), 17-hydroxyprogesterone (17-OH P), corticosterone (B), deoxycortisol (S), cortisol (F), and aldosterone were measured in 8 control subjects and in 10 patients with low and normal renin essential hypertension (EH) before and 4 and 8 h after an iv infusion of 25 units of ACTH." | 3.65 | Response of several adrenal steroids to ACTH stimulation in essential hypertension. ( Genest, J; Guthrie, GP; Honda, M; Kuchel, O; Messerli, FH; Nowaczynski, W; Tolis, G, 1977) |
"The blood pressure response to propranolol treatment was analyzed retrospectively in 187 patients with benign essential hypertension." | 3.65 | Unexpected pressor responses to propranolol in essential hypertension. An interaction between renin, aldosterone and sympathetic activity. ( Case, DB; Drayer, JI; Keim, HJ; Laragh, JH; Weber, MA, 1976) |
"To understand the role of the renin-angiotensin-aldosterone system in the pathogenesis of human hypertension, in serial studies we have blocked the system using three different pharmacologic probes: 1) reduction of renin secretion by administration of the beta receptor blocker, propranolol; 2) blockade of the action of angiotensin II by infusion of saralasin, a competitive antagonist of angiotensin II; and 3) blockade of the enzymatic conversion of angiotensin I to angiotensin II by infusing a nonapeptide competitive inhibitor." | 3.65 | Blockade of renin or angiotensin for understanding human hypertension: a comparison of propranolol, saralasin and converting enzyme blockade. ( Case, DB; Keim, H; Laragh, JH; Wallace, JM, 1977) |
"In various kinds of hypertension clonidine induced a decrease in urinary catecholamines, plasma renin activity and urinary aldosterone, concommitant with a fall in blood pressure and pulse rate in both short term and chronic studies." | 3.65 | The effect of clonidine and penbutolol, respectively on catecholamines in blood and urine, plasma renin activity and urinary aldosterone in hypertensive patients. ( Hansson, BG; Hedeland, H; Hökfelt, B, 1975) |
"To investigate the interaction between the renin angiotensin aldosterone system and the renal prostaglandin (PG), urinary excretion of PGE, urinary excretion of main urinary metabolite (MUM) of PGF2a, urinary excretion of aldosterone, and plasma renin activity were measured before and after infusion of 1-Sar-8-Ile-Angiotensin II, a specific competitive inhibitor of angiotensin II, in 18 patients with essential hypertension under normal and low sodium diets." | 3.65 | Effects of 1-Sar-8-Ile-angiotensin II on urinary prostaglandin excretion in patients with essential hypertension. ( Abe, K; Chiba, S; Irokawa, N; Ito, T; Otsuka, Y; Ritsu, K; Saito, K; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K, 1977) |
"In 79 patients with essential hypertension, treatment with propranolol hydrochloride and chlorthalidone together produced significantly greater falls in both systolic and diastolic blood pressures than were obtained with either drug alone." | 3.65 | Renin reactivity as a determinant of responsiveness to antihypertensive treatment. ( Case, DB; Drayer, JI; Laragh, JH; Lopez-Ovejero, JA; Weber, MA, 1977) |
"This study was undertaken to evaluate the effect of chronic diuretic therapy with chlorothiazide on the course of salt hypertension in hypertension-resistant (R) and hypertension-sensitive (S) strains of rats." | 3.65 | Influence of thiazide on salt hypertension. ( Dahl, LK; Iwai, J; Ohanian, EV, 1977) |
"Chronic hypertension has been produced in mongrel dogs by the long-term oral administration of metyrapone (100 mg/kg per day)." | 3.65 | Multifactorial analysis of chronic hypertension induced by electrolyte-active steroids in trained, unanesthetized dogs. ( Bravo, EL; Dustan, HP; Tarazi, RC, 1977) |
"Adrenal responsiveness to angiotensin II was evaluated in patients with "normal-renin" hypertension." | 3.65 | Aldosterone regulation in essential hypertension: altered adrenal responsiveness to angiotensin II. ( Dluhy, RG; Moore, TJ; Williams, GH, 1977) |
"In 50 patients with essential hypertension treated with chlorthalidone, 100 mg daily for 6 weeks, treatment responders (fall in mean pressure, greater than or equal to 10%) and nonresponders experienced similar weight and electrolyte changes." | 3.65 | Disparate patterns of aldosterone response during diuretic treatment of hypertension. ( Drayer, JI; Laragh, JH; Rev, A; Weber, MA, 1977) |
"To investigate the role of the renin angiotensin system in the pathogenesis of hypertension in Cushing's syndrome two patients with hypercorticism were infused with 20 mg saralasin (1-sar-8-ala-angiotensin II) over a period of 30 minutes under constant blood pressue control." | 3.65 | The effect of saralasin (1sar-8-ala-angiotensin II) on blood pressure in patients with Cushing's syndrome. ( Beckerhoff, R; Cottier, P; Redlich, B; Siegenthaler, W; Vetter, H; Vetter, W, 1976) |
"To investigate the roles of angiotensin II and sodium in essential high-renin, normal-renin and low-renin hypertension, 14 patients received the competitive antagonist of angiotensin II, saralasin, during periods of sodium depletion and repletion." | 3.65 | Reciprocal relation between renin dependency and sodium dependency in essential hypertension. ( Brunner, HR; Gavras, H; Gavras, I; Ribeiro, AB, 1976) |
"Plasma aldosterone concentration (PAC), plasma renin concentration (PRC), plasma potassium, plasma sodium and blood pressure (BP) have been measured in 22 patients with essential hypertension before and after treatment for one month with alprenolol." | 3.65 | Relationship between plasma aldosterone concentration and plasma potassium in patients with essential hypertension during alprenolol treatment. ( Kornerup, HJ; Pedersen, EB, 1976) |
"Compared with a group of normal pregnant women, matched for age, parity, posture, and length of gestation, women with hypertension and proteinuria in the last trimester had significantly lower plasma concentrations of renin, renin substrate and angiotensin II." | 3.65 | Studies of the renin-angiotension-aldosterone system, cortisol, DOC, and ADH in normal and hypertensive pregnancy. ( Doig, A; Fraser, R; Morton, JJ; Parboosingh, J; Robertson, JI; Weir, RJ; Wilson, A, 1976) |
"The effect of saralasin in lowering blood pressure and plasma aldosterone concentration in normal subjects, both sodium-replete and sodium-deplete, and in patients with various forms of hypertension, is closely related to the basal plasma angiotensin II concentration." | 3.65 | The effects of the angiotensin II antagonist saralasin on blood pressure and plasma aldosterone in man in relation to the prevailing plasma angiotensin II concentration. ( Brown, JJ; Brown, WC; Fraser, R; Lever, AF; Morton, JJ; Robertson, JI; Rosei, EA; Trust, PM, 1976) |
"The responses of blood pressure, plasma renin activity (PRA) and plasma aldosterone concentration (PAC) to infusion of either angiotensin II (10 ng/Kg/min) or norepinephrine (100 ng/Kg/min) were observed in 25 patients with essential hypertension." | 3.65 | Effect of pressor agents on blood pressure, plasma renin activity and plasma aldosterone concentration in essential hypertension. ( Yamamoto, Y, 1975) |
"Plasma aldosterone, plasma renin activity, sodium and potassium in the plasma and the urine were determinated under acute stimulation with saline-depletion (furosemide) and under acute suppression with saline infusion in 40 patients with primary hypertension stage I, 19 patients with primary hypertension stages II and III, and 11 patients with renal hypertension (chronic glomerulonephritis and chronic pyelonephritis)." | 3.65 | [Plasma aldosterone and plasma renin activity in patients with essential and renal hypertension under acute stimulation with saline depletion and acute suppression with saline infusion]. ( Klaus, D; Klumpp, F; Lemke, R; Zehner, J; Zöfel, P, 1975) |
"The anti-hypertensive effect of spironolactone and thiabutazide was tested on 47 unselected patients with primary hypertension." | 3.65 | [Spironolactone and thiabutazide in the treatment of essential hypertension (author's transl)]. ( Braun, B; Klaus, D; Klump, F; Lemke, R; Zehner, J; Zöfel, P, 1975) |
"The response of plasma aldosterone to fludrocortisone administration (400 mug 12-hourly for 3 days) was studied in twenty-two patients with primary hyperaldosteronism." | 3.65 | Response of plasma aldosterone to fludrocortisone in primary hyperaldosteronism and other forms of hypertension. ( Allison, ME; Brown, JJ; Ferriss, JB; Fraser, R; Lever, AF; Luke, RG; Padfield, PL; Robertson, JI, 1975) |
"The effects of the antihypertensive imidazoline compounds 2-(5 fluor-0-toluidine)-2-imidazoline hydrochloride (ST 600) and 2-(2, 6 dichlorophenylamine)-2-imidazoline hydrochloride (ST 155, clonidine, Catapres) on intra-arterial pressure, cardiac output, stroke volume, heart rate, total peripheral resistance, renal blood flow, glomerular filtration rate, renal vascular resistance, plasma volume, plasma renin and aldosterone concentration were studied in five patients with essential hypertension." | 3.65 | Comparison between the effects of ST 600 and clonidine. ( Birkenhäger, WH; Kho, TL; Schalekamp, MA; Wester, A; Zaal, GA, 1975) |
"Acebutolol, a new cardioselective beta-blocking agent, has been given for 5 days, at a daily dosage of 600 mg to 8 patients with mild essential hypertension." | 3.65 | [Effects of acebutolol on the renin-aldosterone system in essential arterial hypertension]. ( Corvol, P; Ménard, J; Plouin, PF, 1975) |
" have applied the diazoxide test for the screening of primary hiperaldosteronism to 22 nephropatic patients suffering from hypertension and with different degrees of renal function." | 3.65 | [Diazoxide test in the diagnosis of arterial hypertension: modifications in the levels of renin and aldosterone in blood of patients with various restrains of the renal function]. ( Albertini, A; Cecchettin, M; Ghielmi, S; Maiorca, R; Orlandini, A; Signorini, C, 1975) |
"In 19 control subjects, 33 patients with essential hypertension and normal plasma renin activity (PRA) and 11 patients with low PRA, secretory rates of 18-hydroxy-11-deoxy-corticosterone (18-OH DOC), 11-deoxycorticosterone (DOC) and corticosterone were measured." | 3.65 | Mineralocorticoid secretion in essential hypertension with normal and low plasma renin activity. ( Boucher, R; Genest, J; Honda, M; Kubo, S; Kuchel, O; Messerli, FH; Nowaczynski, W; Seth, K; Tolis, G, 1976) |
"Plasma renin activity, arterial and venous angiotensin II (A II), plasma aldosterone, and sodium excretion were measured in a group of 101 patients with mild essential hypertension." | 3.65 | Relation between plasma renin activity, angiotensin, and aldosterone and blood pressure in mild untreated hypertension. ( Horvath, JS; Moore, MA; Russell, RP; Walker, WG; Whelton, P, 1976) |
"The effect of triamterene, a potassium-retaining natriuretic and diuretic agent, on arterial blood pressure was studied in 31 patients with essential hypertension; there were seven patients with low plasma renin activity and 24 patients with normal plasma renin activity." | 3.65 | Triamterene-induced changes in aldosterone and renin values in essential hypertension. Evidence of a role for aldosterone in preventing blood pressure reduction. ( Drayer, JI; Keim, HJ; Laragh, JH; Thurston, H, 1976) |
"A 44-year old woman without history of hypertension in her 4 pregnancies was hospitalized for hemoptysia and found to have hypertension 230/120 to 250/150: she had been taking 2 tablets of Lyndiol (5 mg lynestrenol and ." | 3.65 | [A case of arterial hypertension imputable to an estroprogestational contraceptive. Implication of the renin-angiotensin-aldosterone system]. ( Béquart, P; Boulangé, M; Camelot, G; Fontenaille, C, 1969) |
"The effect of prolonged preoperative treatment with spironolactone has been studied in a series of 67 patients with hypertension, aldosterone excess, and low plasma renin." | 3.65 | Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin. ( Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Haywood, E; Lever, AF; Robertson, JI, 1972) |
"The content of aldosterone, corticosterone, and cortisol has been assayed in normal adrenal tissue obtained at autopsy and in adrenal adenomas from both normotensive and hypertensive patients obtained at autopsy and from patients with primary aldosteronism obtained at surgery." | 3.64 | The steroid content of adrenal adenomas and measurements of aldosterone production in patients with essential hypertension and primary aldosteronism. ( Kaplan, NM, 1967) |
"Patients with treatment-resistant hypertension who received baxdrostat had dose-related reductions in blood pressure." | 3.30 | Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension. ( Alp, N; Bhatt, DL; Brown, MJ; Freeman, MW; Halvorsen, YD; Isaacsohn, J; Marshall, W; Murphy, B; Pater, M; Pearce, C; Srivastava, A, 2023) |
"High aldosterone is a key driver of hypertension and long-term negative sequelae." | 3.30 | CYP11B2 inhibitor dexfadrostat phosphate suppresses the aldosterone-to-renin ratio, an indicator of sodium retention, in healthy volunteers. ( Brooks, A; Brunner, HR; Groessl, M; Hossack, S; Mulatero, P; Schumacher, C; Steele, RE; Vogt, B, 2023) |
" Salt restriction, cortisol after dexamethasone suppression test and dosage of renin-angiotensin-aldosterone-system (RAAS) blockers were independently associated with BP reduction." | 3.30 | Moderate dietary salt restriction improves blood pressure and mental well-being in patients with primary aldosteronism: The salt CONNtrol trial. ( Adolf, C; Bidlingmaier, M; Britz, V; Heinrich, DA; Kunz, S; Künzel, H; Lechner, A; Müller, LM; Nowotny, HF; Potzel, AL; Reincke, M; Sarkis, AL; Schneider, H; Seiter, TM; Sturm, L, 2023) |
"Obstructive sleep apnea is a chronic, sleep-related breathing disorder, which is an independent risk factor for cardiovascular disease." | 3.01 | Influence and implications of the renin-angiotensin-aldosterone system in obstructive sleep apnea: An updated systematic review and meta-analysis. ( Chai, CS; Goh, SL; Lim, LL; Lim, QH; Loh, HH; Sukor, N; Yee, A, 2023) |
"Primary aldosteronism (PA) is a highly prevalent yet underdiagnosed secondary cause of hypertension." | 3.01 | Personalized Treatment of Patients With Primary Aldosteronism. ( Chen Cardenas, SM; Khairi, S; Obeid, H; Turcu, AF, 2023) |
"Hypertension is the definitive risk factor for cardiovascular disease." | 3.01 | CASZ1: a promising factor modulating aldosterone biosynthesis and mineralocorticoid receptor activity. ( Itoh, H; Kurihara, I; Shibata, H; Sone, M; Yokota, K, 2023) |
"The diagnosis and treatment of primary aldosteronism is of paramount significance, since depending on its subtype, surgical or pharmaceutical intervention can lead to the full recovery of the patient." | 3.01 | [The genetic background of primary aldosteronism]. ( Igaz, P; Vékony, B, 2023) |
"Primary aldosteronism (PA) is the leading cause of curable endocrine hypertension, which is associated with a higher risk of cardiovascular and metabolic insults compared to essential hypertension." | 3.01 | Cardiovascular and metabolic characters of ( Chang, CC; Chang, YY; Chen, ZW; Chou, CH; Hung, CS; Lee, BC; Liao, CW; Lin, YH; Lu, CC; Pan, CT; Peng, KY; Tsai, CH; Wu, VC, 2023) |
"Emerging antenatal risk factors such as preeclampsia appear to increase the risk of hypertension and cardiovascular disease across the life course in both the offspring and women after pregnancy." | 3.01 | Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American ( Alexander, BT; August, P; Bertagnolli, M; Ferranti, EP; Grobe, JL; Jones, EJ; Loria, AS; Safdar, B; Sequeira-Lopez, MLS; South, AM, 2023) |
"Both factors apply to primary aldosteronism, which is woefully underdiagnosed as a cause of hypertension and end-organ damage." | 3.01 | Underdiagnosis of Primary Aldosteronism: A Review of Screening and Detection. ( Bhalla, V; Funes Hernandez, M, 2023) |
"Primary aldosteronism is associated with an increased risk of cardiovascular disease and kidney dysfunction compared to essential hypertension." | 3.01 | The Effect of Aldosterone on Cardiorenal and Metabolic Systems. ( Abe, M; Kobayashi, H; Otsuka, H, 2023) |
"Primary aldosteronism (PA) is characterized by dysregulated, renin-independent aldosterone excess." | 3.01 | Primary Aldosteronism Prevalence - An Unfolding Story. ( Charoensri, S; Turcu, AF, 2023) |
"Primary aldosteronism (PA), once considered a rare disease, is being increasingly recognized as an important cause of hypertension." | 3.01 | Improving Detection Rates for Primary Aldosteronism. ( Fuller, PJ; Libianto, R; Russell, G; Stowasser, M; Yang, J, 2023) |
"Aldosterone measurements have been changed to the CLEIA method." | 3.01 | Recent progress in the diagnosis and treatment of primary aldosteronism. ( Shibata, H; Yoshida, Y, 2023) |
"Aldosterone is a steroid hormone produced in the zona glomerulosa (ZG) of the adrenal cortex." | 3.01 | Ca ( Dinh, HA; Scholl, UI; Stölting, G, 2023) |
"Primary aldosteronism (PA) is the most common cause of secondary hypertension." | 3.01 | Advances in the molecular imaging of primary aldosteronism. ( Cheng, G; Ren, X; Wang, Z, 2023) |
"Primary aldosteronism, or Conn syndrome, is the most common endocrine cause of hypertension." | 3.01 | Mineralocorticoid receptor signalling in primary aldosteronism. ( Cole, TJ; Fuller, PJ; Yang, J; Young, MJ, 2023) |
"Primary aldosteronism (PA) is a leading global cause of secondary hypertension." | 3.01 | Key to the Treatment of Primary Aldosteronism in Secondary Hypertension: Subtype Diagnosis. ( Liu, S; Pang, H; Xu, L; Zuo, R, 2023) |
"Primary aldosteronism (PA), characterized by inappropriately high concentrations of the adrenal-derived hormone aldosterone, is the most common endocrine cause of arterial hypertension." | 3.01 | Primary aldosteronism 2.0: an update for clinicians on diagnosis and treatment. ( Kocjan, T; Pilz, S; Theiler-Schwetz, V; Trummer, C, 2023) |
" The former dosage of ACEis/ARBs was continued in one group while in another group, the ACEis/ARBs were replaced by amlodipine ± carvedilol according to the dose equivalents." | 3.01 | Effects of Renin-Angiotensin-Aldosterone Inhibitors on Early Outcomes of Hypertensive COVID-19 Patients: A Randomized Triple-Blind Clinical Trial. ( Ashraf, H; Bahreini, M; Ghoghaei, M; Najmeddin, F; Rasooli, F; Salehi, M; Soleimani, A; Solhjoo, M, 2021) |
"Aldosterone was not associated with IMMR, insulin sensitivity, or blood pressure and was unaffected by weight loss." | 2.87 | Aldosterone Is Not Associated With Metabolic and Microvascular Insulin Sensitivity in Abdominally Obese Men. ( de Leeuw, PW; Houben, AJHM; Joris, PJ; Kusters, YHAM; Mensink, RP; Plat, J; Schalkwijk, CG; Scheijen, JLJM; Schütten, MTJ; Stehouwer, CDA; van de Waarenburg, MPH, 2018) |
"Hypertension is prevalent in chronic kidney disease (CKD)." | 2.87 | Non-uniform relationship between salt status and aldosterone activity in patients with chronic kidney disease. ( Andrew, R; Freel, EM; Homer, NZM; Jardine, AG; Mark, PB; McQuarrie, EP; Rankin, AJ; Taylor, AHM, 2018) |
"Subjects with hypertension are frequently obese or insulin resistant, both conditions in which hyperuricemia is common." | 2.84 | Dietary Sodium Modifies Serum Uric Acid Concentrations in Humans. ( Johnson, RJ; Kelly, J; MacGinley, RJ; Major, TJ; Merriman, TR; Todd, AS; Walker, RJ, 2017) |
"Aldosterone excretion was determined by 24 h urine (24h-UAldo) collected at randomization and after 6 months of follow-up." | 2.84 | Effects of continuous positive airway pressure treatment on aldosterone excretion in patients with obstructive sleep apnoea and resistant hypertension: a randomized controlled trial. ( Cavalcanti, AH; Cortez, AF; de Souza, F; Margallo, V; Muxfeldt, ES; Salles, GF, 2017) |
"Primary aldosteronism (PA) is the primary cause of secondary hypertension." | 2.82 | Adrenal venous sampling in the diagnostic workup of primary aldosteronism. ( Betz, MJ; Zech, CJ, 2022) |
"After confirmation of Conn's syndrome a differentiation between a unilateral and bilateral adrenal disease is necessary for further treatment planning." | 2.82 | [Conn's syndrome-Frequent and still too rarely diagnosed to underdiagnosed]. ( Adolf, C; Fuss, CT; Hahner, S; Heinrich, DA, 2022) |
"Primary aldosteronism (PA) is an endocrine related condition leading to arterial hypertension due to inappropriately high and unregulated aldosterone concentration." | 2.82 | Primary Aldosteronism, Aldosterone, and Extracellular Vesicles. ( Carvajal, CA; Fardella, CE; Pérez, JA; Tapia-Castillo, A, 2022) |
"Primary aldosteronism (PA) is the most common cause of secondary arterial hypertension." | 2.82 | [Diagnosis of primary hyperaldosteronism]. ( Araujo-Castro, M; Parra-Ramírez, P, 2022) |
"Primary aldosteronism, the most common secondary form of hypertension, is thought to be present in ≈5% to 10% of hypertensive adults." | 2.82 | Primary Aldosteronism: Where Are We Now? Where to From Here? ( Carey, RM; Funder, JW, 2022) |
"Primary aldosteronism (PA) affects millions of individuals worldwide." | 2.82 | High Prevalence of Autonomous Aldosterone Production in Hypertension: How to Identify and Treat It. ( Lieberman, L; Turcu, AF; Wannachalee, T, 2022) |
"Superimposed preeclampsia complicates about 20% of pregnancies in women with chronic hypertension and is associated with increased maternal and perinatal morbidity compared with preeclampsia alone." | 2.82 | Chronic hypertension and superimposed preeclampsia: screening and diagnosis. ( Kametas, NA; Nicolaides, KH; Nzelu, D, 2022) |
"Salt and inflammation are placed in the middle of the mosaic because both factors influence each of the remaining pieces." | 2.82 | Mosaic theory revised: inflammation and salt play central roles in arterial hypertension. ( Benitah, JP; Hengel, FE; Wenzel, UO, 2022) |
"Aldosterone levels were low or in the reference range in 98% of the cases when available." | 2.82 | 11-Deoxycorticosterone Producing Adrenal Hyperplasia as a Very Unusual Cause of Endocrine Hypertension: Case Report and Systematic Review of the Literature. ( Asla, Q; Aulinas, A; Hanzu, FA; Lerma, E; Pérez, JI; Rodrigo, MT; Sardà, H; Urgell, E; Webb, SM, 2022) |
"Primary aldosteronism (PA) is a pathological condition characterized by an excessive aldosterone secretion; once thought to be rare, PA is now recognized as the most common cause of secondary hypertension." | 2.82 | Primary Aldosteronism and Resistant Hypertension: A Pathophysiological Insight. ( Arata, S; Bioletto, F; Bollati, M; Ghigo, E; Lopez, C; Maccario, M; Parasiliti-Caprino, M; Ponzetto, F; Procopio, M, 2022) |
"Primary aldosteronism (PA) is the most common and potentially curable form of secondary hypertension, affecting 5-10% of primary care patients with hypertension." | 2.82 | Performance of the aldosterone-to-renin ratio as a screening test for primary aldosteronism in primary care. ( Ariens, J; Choy, KW; Horvath, AR; Yang, J, 2022) |
"Primary aldosteronism (PA) in pregnancy (PAP) can be a serious condition and is challenging to diagnose." | 2.82 | Management and Outcomes of Primary Aldosteronism in Pregnancy: A Systematic Review. ( Rossi, GP; Rossitto, G; Sanga, V; Seccia, TM, 2022) |
"Primary aldosteronism (PA) is the most common form of secondary arterial hypertension, with a prevalence of approximately 20% in patients with resistant hypertension." | 2.82 | Pathogenesis of Primary Aldosteronism: Impact on Clinical Outcome. ( Almeida, MQ; Guimaraes, AG; Santana, LS, 2022) |
"Primary aldosteronism (PA) is the leading cause of secondary hypertension, accounting for over 10% of patients with high blood pressure." | 2.82 | Update on the Genetics of Primary Aldosteronism and Aldosterone-Producing Adenomas. ( Faucz, FR; Hannah-Shmouni, F; Pitsava, G; Stratakis, CA, 2022) |
"Primary aldosteronism is a common cause of hypertension and is a risk factor for cardiovascular and renal morbidity and mortality, via mechanisms mediated by both hypertension and direct insults to target organs." | 2.82 | Primary aldosteronism - a multidimensional syndrome. ( Turcu, AF; Vaidya, A; Yang, J, 2022) |
" Orthostatic hypotension is a concern with the use of α1-blockers especially in the elderly, and requires careful initial bedtime dosing and avoiding overdosing." | 2.82 | Role of α1-blockers in the current management of hypertension. ( Buranakitjaroen, P; Cheng, HM; Chia, YC; Kario, K; Li, H; Li, Y; Sogunuru, GP; Tay, JC; Van Huynh, M; Wang, JG; Wang, TD; Xu, TY, 2022) |
"Arterial hypertension is a major risk factor for cardiovascular disease." | 2.82 | Who should be screened for primary aldosteronism? A comprehensive review of current evidence. ( Chen, CH; Cheng, HM; Chia, YC; Huang, WC; Kario, K; Lin, YH; Siddique, S; Sogunuru, G; Tay, JC; Wu, VC, 2022) |
"Both primary aldosteronism and obstructive sleep apnea are well-known causes of hypertension and contribute to increased cardiovascular morbidity and mortality independently." | 2.82 | Primary aldosteronism and obstructive sleep apnea: What do we know thus far? ( Loh, HH; Sukor, N, 2022) |
"Primary aldosteronism is the most common form of secondary arterial hypertension, due to excessive aldosterone production from the adrenal gland." | 2.82 | Vascular and hormonal interactions in the adrenal gland. ( Abdellatif, AB; Boulkroun, S; Fernandes-Rosa, FL; Zennaro, MC, 2022) |
"Hypertension is a major public health problem, affecting more than a quarter of the world's population causing serious cardiovascular problems." | 2.82 | New Genetic Polymorphisms as an Epidemiological Factor of Arterial Hypertension in Patients with Hyposodical Diet. ( Aguilar Aldrete, ME; Cabrera-Pivaral, CE; Flores-Alvarado, LJ; López-Toledo, S; Parada-Luna, F; Ramírez-García, SA; Ruiz, DM, 2022) |
"Increased abdominal obesity is associated with increased cardiovascular risk, especially in African American women." | 2.82 | Relationship Between Obesity, Hypertension, and Aldosterone Production in Postmenopausal African American Women: A Pilot Study. ( Bakris, GL; Laffin, LJ; Liao, C; Majewski, C, 2016) |
"Observational studies in primary hyperaldosteronism suggest a positive relationship between aldosterone and parathyroid hormone (PTH); however, interventions to better characterize the physiological relationship between the renin-angiotensin-aldosterone system (RAAS) and PTH are needed." | 2.79 | Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone. ( Adler, GK; Brown, JM; Garg, R; Garza, AE; Luther, JM; Pojoga, LH; Ruan, DT; Vaidya, A; Williams, GH; Williams, JS, 2014) |
"The high prevalence of obstructive sleep apnea in patients with resistant hypertension could be mediated by an activation of the renin-angiotensin-aldosterone system." | 2.79 | A randomized controlled study of CPAP effect on plasma aldosterone concentration in patients with resistant hypertension and obstructive sleep apnea. ( Espinel, E; Ferrer, R; Lloberes, P; Martínez-Garcia, MA; Ramon, MA; Romero, O; Sampol, G; Segarra, A; Tovar, JL, 2014) |
"Primary aldosteronism (PA) is an established cause of hypertension, whereas high-normal serum aldosterone levels have been linked to an increased risk for hypertension." | 2.78 | Evidence of primary aldosteronism in a predominantly female cohort of normotensive individuals: a very high odds ratio for progression into arterial hypertension. ( Chrousos, GP; Gouli, A; Kaltsas, G; Markou, A; Mitsakis, K; Papanastasiou, L; Pappa, T; Piaditis, GP; Prevoli, A; Tsiavos, V; Tsounas, P; Zografos, G, 2013) |
"Inflammation is considered as a major effector of arterial damage brought about by salt excess in animal models." | 2.78 | Procalcitonin and the inflammatory response to salt in essential hypertension: a randomized cross-over clinical trial. ( Cutrupi, S; Leonardis, D; Mallamaci, F; Pizzini, P; Tripepi, G; Zoccali, C, 2013) |
"Aldosterone breakthrough was observed in 22 of the subjects (55%)." | 2.78 | Effect of aldosterone breakthrough on albuminuria during treatment with a direct renin inhibitor and combined effect with a mineralocorticoid receptor antagonist. ( Fukuda, S; Sato, A, 2013) |
"Primary aldosteronism is the most frequent cause of secondary hypertension and is associated with more prominent left ventricular hypertrophy and increased myocardial fibrosis." | 2.77 | Adrenalectomy reverses myocardial fibrosis in patients with primary aldosteronism. ( Chang, HW; Chueh, SC; Ho, YL; Lee, HH; Lee, JK; Lin, CY; Lin, LC; Lin, YH; Liu, YC; Lo, MT; Wu, KD; Wu, VC; Wu, XM, 2012) |
"In patients with primary aldosteronism, adrenal vein sampling (AVS) is considered the only reliable technique to distinguish between unilateral and bilateral autonomous production of aldosterone, but agreement is lacking on the best criteria indicating successful cannulation and lateralization." | 2.75 | Impact of different diagnostic criteria during adrenal vein sampling on reproducibility of subtype diagnosis in patients with primary aldosteronism. ( Bertello, C; Daunt, N; Gordon, R; Leggett, D; Mengozzi, G; Mulatero, P; Rossato, D; Stowasser, M; Sukor, N; Veglio, F, 2010) |
"Angiotensin-converting enzyme (ACE) inhibitors differ in their lipophilic/hydrophilic index that determines their tissue bioavailability and affinity to ACE, which may result in major differences in the degree of blockade of cardiac ACE." | 2.75 | Effects of ACE inhibitors on cardiac angiotensin II and aldosterone in humans: "Relevance of lipophilicity and affinity for ACE". ( Coletta, E; Davies, R; Haddad, H; Leenen, FH; Ruzicka, M; White, R, 2010) |
"Aldosterone was positively related to PRA and progesterone." | 2.74 | The ovarian cycle as a factor of variability in the laboratory screening for primary aldosteronism in women. ( Di Cecco, P; Fommei, E; Ghione, S; Iervasi, A; Maffei, S; Ripoli, A; Turchi, S, 2009) |
"Aldosterone production causes vascular injury and may occur despite the long-term administration of angiotensin converting enzyme-inhibitors (ACE-I) (ie, aldosterone breakthrough)." | 2.74 | Effects of ARB or ACE-inhibitor administration on plasma levels of aldosterone and adiponectin in hypertension. ( Hoshino, J; Hosoi, T; Iwasaki, T; Kawachi, K; Kurabayashi, M; Morishita, K; Nakamura, T; Ohyama, Y; Saito, T; Saito, Y, 2009) |
"People with prehypertension are at risk of developing hypertension, being a biomarker for cardiovascular disease risk." | 2.73 | Bovine casein hydrolysate (c12 Peptide) reduces blood pressure in prehypertensive subjects. ( Cadée, JA; Chang, CY; Chen, CW; Chen, SL; Huang, CN; Wang, CK, 2007) |
"Amiloride 40 mg was as effective as the other diuretics." | 2.73 | The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio. ( Ashby, MJ; Brown, MJ; Hood, SJ; Taylor, KP, 2007) |
"We studied 30 patients with type 2 diabetes mellitus (mean age 43." | 2.73 | Gradual reactivation of vascular angiotensin I to angiotensin II conversion during chronic ACE inhibitor therapy in patients with diabetes mellitus. ( Morris, AD; Sharman, DC; Struthers, AD, 2007) |
"Aldosterone is an important pathogenetic factor, independent of the renin-angiotensin system in cardiovascular and renal disease." | 2.73 | Aldosterone breakthrough during angiotensin II receptor blockade in hypertensive patients with diabetes mellitus. ( Karashima, S; Oda, N; Takata, H; Takeda, Y; Usukura, M; Yamagishi, M; Yamamoto, Y; Yoneda, T, 2007) |
"Primary aldosteronism is a common cause of secondary hypertension associated with excess cardiovascular morbidities." | 2.72 | Diagnosis and treatment of primary aldosteronism. ( Bancos, I; Mulatero, P; Reincke, M; Scholl, UI; Stowasser, M; Williams, TA, 2021) |
"Hypertension is highly prevalent in Black Africans and has been found to be associated with worse blood pressure (BP) control and more cardiovascular disease." | 2.72 | The importance of the epithelial sodium channel in determining salt sensitivity in people of African origin. ( Jones, E; Rayner, B, 2021) |
"Primary aldosteronism (PA), the most common form of secondary hypertension, has been considered for decades as a "benign" form of hypertension, but evidences progressively built up to show that patients with PA had an excess rate of cardiovascular damage as compared to blood pressure-matched essential hypertensive patients." | 2.72 | The cardiovascular consequences of hyperaldosteronism. ( Cesari, M; Maiolino, G; Rossi, GP; Seccia, TM, 2021) |
"Aldosterone is a mineralocorticoid hormone that controls body fluid and electrolyte balance." | 2.72 | Aldosterone, Inflammation, Immune System, and Hypertension. ( Ferreira, NS; Paradis, P; Schiffrin, EL; Tostes, RC, 2021) |
"Primary aldosteronism (PA) is a common cause of secondary hypertension and is associated with worse cardiovascular outcomes." | 2.72 | Left ventricular remodeling and dysfunction in primary aldosteronism. ( Chang, YY; Chen, ZW; Hung, CS; Lin, YH; Pan, CT; Tsai, CH; Wu, VC, 2021) |
"Metabolic syndrome is a cluster of conditions that increase the risk of cardiovascular diseases, and comprises obesity, hypertension, impaired glucose metabolism and dyslipidaemia." | 2.72 | The mineralocorticoid receptor-an emerging player in metabolic syndrome? ( Stowasser, M; Thuzar, M, 2021) |
"Hyperaldosteronism can occur either as primary aldosteronism (renin-independent) or secondary aldosteronism (renin-dependent)." | 2.72 | [Hyperaldosteronism]. ( Scholl, UI, 2021) |
"In adults, obesity is often associated with salt-sensitive hypertension." | 2.72 | Kidney and epigenetic mechanisms of salt-sensitive hypertension. ( Fujita, T; Kawarazaki, W, 2021) |
"Primary aldosteronism, characterized by renin-independent aldosterone secretion from one or both adrenal glands, is the most common and modifiable form of secondary hypertension." | 2.72 | How common is primary aldosteronism? ( Hundemer, GL; Kline, GA; Leung, AA, 2021) |
"Primary aldosteronism (PA) is one of the most frequent curable forms of secondary hypertension." | 2.72 | Functional Characteristic and Significance of Aldosterone-Producing Cell Clusters in Primary Aldosteronism and Age-Related Hypertension. ( Azizan, EA; Pauzi, FA, 2021) |
"Primary aldosteronism (PA), a condition characterized by autonomous aldosterone hypersecretion, constitutes the most common cause of secondary hypertension." | 2.72 | Unravelling the Genetic Basis of Primary Aldosteronism. ( Charmandari, E; Markou, A; Mourtzi, N; Piaditis, GP; Sertedaki, A, 2021) |
"Primary aldosteronism (PA) is the most common cause of secondary hypertension and is significantly under-diagnosed." | 2.72 | Therapeutic Outcomes with Surgical and Medical Management of Primary Aldosteronism. ( Fraker, DL; Wachtel, H, 2021) |
"Primary aldosteronism (PA) is the most common cause of secondary hypertension." | 2.72 | Primary Aldosteronism: a Continuum from Normotension to Hypertension. ( Turcu, AF; Wannachalee, T, 2021) |
"Rofecoxib caused an increase in BP compared to celecoxib; a change in recumbent systolic BP +/- SD (6." | 2.72 | Can the blood pressure effects of COX-2 selective inhibitors be explained by changes in plasma aldosterone levels? ( Aw, TJ; Billah, B; Krum, H; Liew, D; Morel-Kopp, MC; Schneider, HG; Tofler, GH, 2006) |
" Group H showed significantly smaller furosemide dosage in the initial 3 days (H vs." | 2.71 | Synthetic human alpha-atrial natriuretic peptide improves the management of postoperative hypertension and renal dysfunction after the repair of abdominal aortic aneurysm. ( Akedo, H; Hayashi, Y; Hiraishi, T; Kobayashi, Y; Matsuda, H; Ohtani, M; Sawa, Y, 2003) |
"The ARR threshold to screen for primary aldosteronism may be based on measurement of irR." | 2.71 | Active renin versus plasma renin activity to define aldosterone-to-renin ratio for primary aldosteronism. ( Ferrari, P; Nicod, J; Nussberger, J; Saner, E; Shaw, SG, 2004) |
"Aldosterone antagonism has BP-independent effects on arterial stiffness." | 2.71 | Aldosterone-to-renin ratio, arterial stiffness, and the response to aldosterone antagonism in essential hypertension. ( Feely, J; Mahmud, A, 2005) |
"Hypertension is the most common cardiovascular complication after liver transplantation." | 2.71 | Mechanisms of hypertension after liver transplantation. ( Alexander, GJ; Brown, MJ; Neal, DA; Wilkinson, IB, 2005) |
"Hypertension is commonly associated with chronic renal disease in cats, and inappropriate activation of the renin-angiotensin-aldosterone system (RAAS) may contribute to the hypertensive state." | 2.70 | Effects of angiotensin-converting enzyme inhibition on plasma aldosterone concentration, plasma renin activity, and blood pressure in spontaneously hypertensive cats with chronic renal disease. ( Henik, RA; Steele, JL; Stepien, RL, 2002) |
"Primary hyperaldosteronism was confirmed if plasma renin activity was <1." | 2.70 | Hyperaldosteronism among black and white subjects with resistant hypertension. ( Calhoun, DA; Nishizaka, MK; Thakkar, RB; Weissmann, P; Zaman, MA, 2002) |
"Primary aldosteronism is a specifically treatable and potentially curable form of secondary hypertension." | 2.70 | Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism. ( Chiandussi, L; Milan, A; Morello, F; Mulatero, P; Paglieri, C; Rabbia, F; Veglio, F, 2002) |
"Telmisartan is a new angiotensin receptor antagonist possessing potent, selective, and insurmountable inhibitory activity specific to the angiotensin II type 1 (AT 1 ) receptor." | 2.70 | Inhibitory effect of telmisartan on the blood pressure response to angiotensin II challenge. ( de Bruin, H; Jonkman, JH; Meinicke, T; Stangier, J; Su, CA; Tamminga, WJ; van Heiningen, PN; van Lier, JJ, 2001) |
" In hypertensive patients, the long-term administration of olmesartan, a novel AT1 receptor antagonist, decreased both blood pressure and plasma angiotensin II levels." | 2.70 | Long-term effects of olmesartan, an Ang II receptor antagonist, on blood pressure and the renin-angiotensin-aldosterone system in hypertensive patients. ( Ichikawa, S; Takayama, Y, 2001) |
"When amiloride was withdrawn for 2 weeks, there was a large increase in blood pressure of 17/8+/-4/2 mm Hg (systolic, P<0." | 2.70 | Amiloride, a specific drug for hypertension in black people with T594M variant? ( Baker, EH; Dong, Y; Duggal, A; Ireson, NJ; MacGregor, GA; Markandu, ND; Wood, M, 2002) |
"Eprosartan was titrated from 200 mg b." | 2.69 | Effects of eprosartan versus enalapril in hypertensive patients on the renin-angiotensin-aldosterone system and safety parameters: results from a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group. ( Gavras, H; Gavras, I, 1999) |
"Spironolactone was a highly effective antihypertensive agent in hypertensive patients who had a raised aldosterone/renin ratio." | 2.69 | Raised aldosterone to renin ratio predicts antihypertensive efficacy of spironolactone: a prospective cohort follow-up study. ( Jung, RT; Lim, PO; MacDonald, TM, 1999) |
"In familial hyperaldosteronism type I, inheritance of a hybrid 11beta-hydroxylase/aldosterone synthase gene leads to ACTH-regulated overproduction of aldosterone (causing hypertension) and of "hybrid" steroids, 18-hydroxy- and 18-oxo-cortisol." | 2.69 | Treatment of familial hyperaldosteronism type I: only partial suppression of adrenocorticotropin required to correct hypertension. ( Bachmann, AW; Gordon, RD; Huggard, PR; Rossetti, TR; Stowasser, M, 2000) |
"This study was designed to compare with placebo the dose-response of conjugated equine oestrogen (CEE) on blood pressure in hypertensive postmenopausal women." | 2.69 | Dose response effect of conjugated equine oestrogen on blood pressure in postmenopausal women with hypertension. ( Harvey, PJ; Molloy, D; Upton, J; Wing, LM, 2000) |
"Losartan appears to be an effective anti-hypertensive agent in patients with mild to moderate hypertension." | 2.68 | Effects of losartan on the renin-angiotensin-aldosterone axis in essential hypertension. ( Bauer, IH; Lau-Sieckman, A; Reams, GP; Wu, Z, 1995) |
" All patients received three dosing regimens administered in random order: (a) intravenous frusemide: 40 mg bolus then 40 mg h-1 for 3 h, (b) captopril: two 12." | 2.68 | The renin angiotensin aldosterone system and frusemide response in congestive heart failure. ( Cerimele, B; Greene, P; Reed, S; Ryan, T; Schwertschlag, U; Voelker, J; Weinberger, M, 1995) |
"Neuropeptide Y (NPY) has been recently characterized as a circulating vasoconstrictor peptide which is co-stored with noradrenaline in sympathetic neurons." | 2.68 | [Concentration of neuropeptide Y in serum of patients with primary hypertension]. ( Halawa, B; Salomon, P, 1996) |
"Essential hypertension is a very common disease in the world." | 2.68 | [Selected components of the kallikrein-kinin system and of the renin-angiotensin-aldosterone system in offspring of parents with hypertension]. ( Marzecka, J, 1996) |
"Fludrocortisone was given daily for 1 week and circulating components of the plasma and tissue kallikrein-kinin systems and renin-angiotensin-aldosterone system were measured repeatedly." | 2.68 | Circulating kallikreins in normotensive and hypertensive humans: effects of mineralocorticoid administration. ( Ohman, KP, 1997) |
"Fourteen subjects with untreated essential hypertension were subjected to 2-h water immersion (WI) study." | 2.67 | Regulation of sodium excretion in human hypertension: long-term effects of calcium antagonist and angiotensin converting enzyme inhibitor. ( Coruzzi, P; Mossini, GL; Musiari, L; Novarini, A, 1993) |
"Losartan (DuP 753) is a novel orally active angiotensin II antagonist that lowers blood pressure." | 2.67 | Hemodynamic and humoral effects of the angiotensin II antagonist losartan in essential hypertension. ( Carroll, J; Grossman, E; Peleg, E; Rosenthal, T; Shamiss, A, 1994) |
" Thus, this long-term study provides additional evidence that diuretics have a flat dose-response curve with respect to their antihypertensive efficacy, whereas lower doses might cause less pronounced activation of counter-regulatory systems." | 2.67 | Long-term diuretic therapy: effects of dose reduction on antihypertensive efficacy and counterregulatory systems. ( Ripka, O; Weisser, B, 1992) |
" Blood pressure was dose-dependently reduced over the full 24-hour dosing period with more pronounced effects on day 8 than on day 1." | 2.67 | Hemodynamic and humoral effects of the novel calcium antagonist Ro 40-5967 in patients with hypertension. ( Belz, GG; Feifel, U; Halabi, A; Kirch, W; Kleinbloesem, CH; Pozenel, H; Schmitt, R; Schroeter, V; Welker, HA; Woittiez, AJ, 1992) |
"These results show that a first-step treatment of hypertension with converting enzyme inhibitors permits better left ventricular function and improves exercise tolerance by way of renin-angiotensin-aldosterone system inhibition." | 2.67 | Comparisons of long-term effects between converting enzyme inhibitors and conventional therapy in treating mild to moderate hypertension. ( Chen, CY; Chiang, HT; Lin, M, 1991) |
" Doxazosin produced rightward shifts of the PE pressor dose-response curves but had no effect on responses to AII." | 2.67 | Vascular pressor responses in treated and untreated essential hypertension. ( Donnelly, R; Elliott, HL; Howie, CA; Reid, JL; Sumner, DJ, 1990) |
"Treatment with felodipine ER over 2 weeks increased sympathetic outflow as indicated by elevated plasma norepinephrine levels, whereas plasma epinephrine was mainly unaffected, as were plasma renin and aldosterone levels." | 2.67 | Catecholamines and the renin-angiotensin-aldosterone system during treatment with felodipine ER or hydrochlorothiazide in essential hypertension. ( Binner, L; Gabrielsen, F; Hombach, V; Koenig, W; Rosenthal, J; Sund, M, 1991) |
" Perindopril alone tended to reduce serum and urinary thromboxane B2 (TxB2) and to raise urinary 6-ketoPGF1 alpha and PGE2 and inhibited serum ACE activity 24 h post dosing by about 85%." | 2.67 | Hemodynamic and humoral interactions between perindopril and indomethacin in essential hypertensive subjects. ( Abdel-Haq, B; Favilla, S; Magagna, A; Salvetti, A, 1991) |
"Aldosterone levels were also increased after three months, but without a subsequent decrease." | 2.67 | Isradipine in the treatment of hypertension. Some additional effects observed during a one-year study. ( Mayer, O; Polivkova, H; Rottenborn, J, 1991) |
"Nicardipine (80 mg/day) was given orally for 12 weeks and no dietary restrictions were imposed." | 2.67 | Efficacy of nicardipine slow release (SR) on hypertension, potassium balance and plasma aldosterone in idiopathic aldosteronism. ( Bisbocci, D; Chiandussi, L; Pinna, G; Piras, D; Rabbia, F; Veglio, F, 1990) |
"Primary aldosteronism is currently considered to represent 5-13% of hypertension, yet fewer than 1% of patients with the disorder are ever diagnosed and treated." | 2.66 | Primary aldosteronism: Treatment of the disease, and new therapeutic approaches. ( Funder, J, 2020) |
"Primary aldosteronism (PA), the most common cause of secondary hypertension, is a well-recognized condition that can lead to cardiovascular and renal complications." | 2.66 | Associations between primary aldosteronism and diabetes, poor bone health, and sleep apnea-what do we know so far? ( Loh, HH; Sukor, N, 2020) |
"Primary aldosteronism (PA) is the most common potentially curable form of hypertension." | 2.66 | Prevalence, diagnosis and outcomes of treatment for primary aldosteronism. ( Reincke, M; Williams, TA; Yang, Y, 2020) |
"Primary aldosteronism (PA) is the most common form of secondary hypertension affecting 5%-10% of patients with arterial hypertension." | 2.66 | Old and new genes in primary aldosteronism. ( Boulkroun, S; Fernandes-Rosa, FL; Zennaro, MC, 2020) |
"Primary aldosteronism (PA) is the most common form of endocrine hypertension." | 2.66 | Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism. ( Gong, S; Meyer, LS; Reincke, M; Williams, TA, 2020) |
"Primary aldosteronism (PA) is the most common cause of secondary hypertension." | 2.66 | The Potential Role of Aldosterone-Producing Cell Clusters in Adrenal Disease. ( Lim, JS; Rainey, WE, 2020) |
"Conn, primary aldosteronism (PA) today is well established as a relevant cause of secondary hypertension and accounts for about 5-10 % of hypertensives." | 2.66 | Salt Appetite and its Effects on Cardiovascular Risk in Primary Aldosteronism. ( Adolf, C; Handgriff, L; Heinrich, DA; Reincke, M; Schneider, H, 2020) |
"Hypokalemia is closely linked with the pathophysiology of primary aldosteronism (PA)." | 2.66 | Hypokalemia and the Prevalence of Primary Aldosteronism. ( Beuschlein, F; Gruber, S, 2020) |
"Hypertension is characteristically associated with vascular dysfunction, cardiovascular remodelling, renal dysfunction, and stimulation of the sympathetic nervous system." | 2.66 | Oxidative Stress: A Unifying Paradigm in Hypertension. ( Alves-Lopes, R; Camargo, LL; Montezano, AC; Neves, KB; Rios, FJ; Touyz, RM, 2020) |
"Primary aldosteronism (PA) is the most common cause of secondary hypertension." | 2.66 | [Update and Research Progress in the Diagnosis of Primary Aldosteronism]. ( Chen, T; Li, YM; Ren, Y; Tian, HM, 2020) |
"Primary aldosteronism is associated with higher cardiovascular and renal morbidity and mortality than essential hypertension in age- and sex-matched patients with the same degree of blood pressure elevation." | 2.66 | Treatment of primary hyperaldosteronism. ( Araujo-Castro, M, 2020) |
"The landscape of primary aldosteronism has evolved to recognize that it is a prevalent syndrome of renin-independent aldosterone production that contributes to the pathogenesis of hypertension and cardiovascular disease." | 2.66 | Evolution of the Primary Aldosteronism Syndrome: Updating the Approach. ( Carey, RM; Vaidya, A, 2020) |
"Primary hyperaldosteronism (PA) is a well-known cause of hypertension although its exact prevalence amongst patients with apparent essential hypertension has been a matter of debate." | 2.66 | Five Reasons for the Failure to Diagnose Aldosterone Excess in Hypertension. ( Chrousos, GP; Kaltsas, G; Markou, A; Piaditis, GP, 2020) |
"Captopril when dosed to lower diastolic blood pressure 5-7 mm Hg did not significantly affect GFR, RPF or RVR." | 2.66 | Preliminary observations of the acute effects of selective serum thromboxane inhibition and angiotensin converting enzyme inhibition on blood pressure and renal hemodynamics in hypertensive humans. ( Douglas, FL; Hoover, N; Klassen, DK; Weir, MR, 1989) |
" In the clinical development of an antihypertensive drug, the earlier use of such within-patient studies, with the random insertion of one placebo period between the active periods, should help in the dose-response curve search." | 2.66 | Crossover design for the dose determination of an angiotensin converting enzyme inhibitor in hypertension. ( Bellet, M; Corvol, P; Guyene, TT; Ménard, J; Sassano, P; Serrurier, D, 1989) |
"Bopindolol is a new long-acting, nonselective beta-adrenoceptor antagonist with partial agonist activity." | 2.66 | The clinical pharmacology of bopindolol, a new long-acting beta-adrenoceptor antagonist, in hypertension. ( Boomsma, F; Derkx, FH; Man in 't Veld, AJ; Mulder, P; Schalekamp, MA; van den Meiracker, AH; van Eck, HJ, 1987) |
"Aldosterone changes on treatment were marginal and nonsignificant." | 2.66 | Effects of fosenopril, a once-daily angiotensin-converting enzyme inhibitor, on resting and exercise-induced changes of blood pressure, hormonal variables, and plasma potassium in essential hypertension. ( Cervenka, J; Dineen, M; O'Connor, DT; Sullivan, PA, 1988) |
"Celiprolol is a newly developed cardioselective beta-blocking agent with mild beta 2-agonist and weak alpha 2-antagonist properties." | 2.66 | Effects of celiprolol on plasma renin, aldosterone, norepinephrine and epinephrine in primary hypertension. ( DeQuattro, V; Hernandez, PH; Kimura, S; Lee, DD, 1988) |
" Further measurements were made during a series of intensive study days, and the most important additional finding was a pharmacokinetic interaction that resulted in increased peak concentrations and bioavailability of prazosin." | 2.66 | The combination of prazosin and verapamil in the treatment of essential hypertension. ( Campbell, L; Elliott, HL; Meredith, PA; Reid, JL, 1988) |
"Nicardipine appears to blunt the secretion of aldosterone responding to an increased PRA possibly through its calcium-antagonizing action." | 2.66 | Multiple oral doses of nicardipine, a calcium-entry blocker: effects on renal function, plasma renin activity, and aldosterone concentration in mild-to-moderate essential hypertension. ( Aoyagi, K; Baba, T; Ishizaki, T; Murabayashi, S; Takebe, K; Tamasawa, N, 1987) |
"Domperidone pretreatment prevented the GFR increase induced by nicardipine and increased the noradrenaline response (+107%), but did not change the other actions of nicardipine." | 2.66 | Haemodynamic (systemic and renal) and humoral interactions between nicardipine and domperidone in hypertensives. ( Lucarini, AR; Salvetti, A, 1987) |
" The mean supine BP 24 hours post dosing were 177/110 mmHg (placebo), 173/109 mmHg (propranolol) and 164/100 mmHg (atenolol)." | 2.66 | Atenolol or propranolol in hypertensive patients poorly controlled on captopril and frusemide. ( Lovell, HG; Petrie, JC; Robb, OJ; Webster, J; Witte, K, 1987) |
"Guanfacine monotherapy was again shown to be an effective initial treatment for mild essential hypertension with no adverse influence on serum lipids." | 2.66 | Guanfacine as monotherapy for systemic hypertension. ( Blackshear, JL; Fillingim, JM; Strauss, A; Strauss, M, 1986) |
" The cardiovascular responses to the chronic administration of CL 115347 were studied in a double-blind, placebo-controlled trial in 26 subjects with essential hypertension (16 given drug, 10 placebo) maintained on a 100-mEq sodium diet." | 2.66 | Prostaglandin E2 analogue elicits renal and hormonal compensatory mechanisms in human hypertension. ( Akester, J; Black, HR; Dzau, VJ; Francis, C; Given, BD; Koury, K; Lasseter, K; Mickiewicz, C; Morray, RL; Vita, NA, 1986) |
"Captopril was administered orally in 2 daily doses of 25 to 200 mg." | 2.65 | Uncontrollable hypertension in patients on hemodialysis: long-term treatment with captopril and salt subtraction. ( Brunner, HR; Gavras, H; Guignard, JP; Turini, GA; Waeber, B; Wauters, JP, 1981) |
" The results obtained from single-blind, placebo-controlled studies indicate that indapamide is a safe and effective agent to use in lowering the blood pressure of hypertensive patients with normal renal function, those with various degrees of renal impairment, and those who are undergoing long-term maintenance hemodialysis." | 2.65 | Clinical efficacy, safety, and pharmacokinetics of indapamide in renal impairment. ( Acchiardo, SR; Skoutakis, VA, 1983) |
"In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)." | 2.65 | [Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984) |
"Hypertension was not caused by 5 days of administration of aldosterone, 18-hydroxydeoxycorticosterone (18-OH-DOC) at 1 mg/day, or deoxycorticosterone (DOC) at 30 mg/day." | 2.64 | Mineralocorticoid hypertension in childhood. ( Levine, LS; New, MI, 1977) |
"Labetalol was more effective in lowering blood pressure but less effective in reducing pulse rate of plasma angiotensin II concentration." | 2.64 | Effect of blood pressure angiotensin II and aldosterone concentrations during treatment of severe hypertension with intravenous labetalol: comparison with propranolol. ( Brown, JJ; Fraser, R; Lever, AF; Morton, JJ; Robertson, JI; Rosei, EA; Trust, PM, 1976) |
"Treatment with propranolol resulted in marked suppression of the plasma renin activity (1." | 2.64 | Intrapatient comparison of treatment with chlorthalidone, spironolactone and propranolol in normoreninemic essential hypertension. ( Benraad, TJ; Drayer, JI; Festen, J; Kloppenborg, PW; van't Laar, A, 1975) |
"Hypertension is a significant public health problem." | 2.61 | Monogenic hypertension. ( Bertelli, M; Dallavilla, T; Guerri, G; Krasi, G; Marinelli, C; Perrone, M; Precone, V; Romeo, F; Stuppia, L; Zulian, A, 2019) |
"Low-renin hypertension affects 30% of hypertensive patients." | 2.61 | Low-Renin Hypertension. ( Athimulam, S; Bancos, I; Lazik, N, 2019) |
"Resistant hypertension is a common clinical entity, defined as suboptimal blood pressure response to multiple therapies after excluding medication nonadherence and secondary forms of hypertension." | 2.61 | Resistant Hypertension: A Clinical Perspective. ( Gubbi, S; Hannah-Shmouni, F; Koch, CA; Spence, JD; Stratakis, CA, 2019) |
"Primary aldosteronism (PA) is a common, but frequently overlooked, cause of arterial hypertension and excess cardiovascular events, particularly atrial fibrillation." | 2.61 | Primary Aldosteronism: JACC State-of-the-Art Review. ( Rossi, GP, 2019) |
"Refractory hypertension is defined as uncontrolled blood pressure despite use of ≥5 antihypertensive agents of different classes, including a long-acting thiazide-like diuretic and an MR (mineralocorticoid receptor) antagonist, at maximal or maximally tolerated doses." | 2.61 | Treatment of Resistant and Refractory Hypertension. ( Acelajado, MC; Calhoun, DA; Hughes, ZH; Oparil, S, 2019) |
"Primary aldosteronism (PA) is the most prevalent cause of secondary hypertension (3%-32% of hypertensive patients)." | 2.61 | The aldosterone to renin ratio in the diagnosis of primary aldosteronism: Promises and challenges. ( Denieffe, S; Fitzgibbon, MC; Griffin, TP; O'Shea, PM, 2019) |
"Primary aldosteronism is the most common form of secondary hypertension." | 2.58 | Overview of aldosterone-related genetic syndromes and recent advances. ( Boulkroun, S; Fernandes-Rosa, FL; Zennaro, MC, 2018) |
"Moreover, primary aldosteronism patients are exposed to an increased risk of cardio and cerebrovascular events and metabolic comorbidities compared with patients affected by essential hypertension." | 2.58 | Primary aldosteronism in the primary care setting. ( Buffolo, F; Monticone, S; Mulatero, P; Tetti, M, 2018) |
"All physicians who treat hypertension should routinely screen appropriate patients for PA." | 2.58 | Primary Aldosteronism: Practical Approach to Diagnosis and Management. ( Auchus, RJ; Byrd, JB; Turcu, AF, 2018) |
"Aldosterone has also been shown to increase blood pressure by a direct activation of the sympathetic nervous system, to cause endothelial and vascular smooth muscle cell dysfunction, myocardial remodeling and fibrosis, and to have pro-arrhythmogenic actions in the heart." | 2.55 | Mineralocorticoid Receptor Blockade in End-Stage Renal Disease. ( Gosmanova, EO; Lyubarova, R, 2017) |
" An assessment of dose-response was also undertaken." | 2.55 | The association between consistent licorice ingestion, hypertension and hypokalaemia: a systematic review and meta-analysis. ( Eslick, EM; Eslick, GD; Penninkilampi, R, 2017) |
"Primary aldosteronism (PA) is the most common form of secondary hypertension and is critical to identify because when caused by an aldosterone-producing adenoma (APA) or another unilateral form, it is potentially curable, and even when caused by bilateral disease, antihypertensives more specific to PA treatment can be employed (ie, aldosterone antagonists)." | 2.55 | Adrenal venous sampling for primary aldosteronism: laboratory medicine best practice. ( Holmes, DT; Kline, G, 2017) |
"Hyperaldosteronism is the leading cause of secondary hypertension with up to 80% due to APA, statistically the most common functioning adrenal nodule." | 2.55 | Radiofrequency ablation treatment for aldosterone-producing adenomas. ( Faintuch, S; Sacks, AC; Sacks, BA, 2017) |
"Primary aldosteronism (PA) is associated with a high rate of cardio- and cerebrovascular complications and metabolic alterations." | 2.53 | Issues in the Diagnosis and Treatment of Primary Aldosteronism. ( Buffolo, F; Burrello, J; Giraudo, G; Monticone, S; Mulatero, P; Schiavone, D; Tetti, M; Veglio, F, 2016) |
"Aldosterone also promotes collagen synthesis, which leads to increased arterial stiffness and elevation of blood pressure." | 2.53 | Resistant Hypertension and the Pivotal Role for Mineralocorticoid Receptor Antagonists: A Clinical Update 2016. ( Duprez, DA; Epstein, M, 2016) |
"Obese subjects often exhibit hyperaldosteronism, with increased salt sensitivity of blood pressure (BP)." | 2.53 | The Role of Aldosterone in Obesity-Related Hypertension. ( Fujita, T; Kawarazaki, W, 2016) |
"Primary aldosteronism (PA) is the most common secondary cause of hypertension, accounting for 10 % of hypertensives and 20 % of those with drug-resistant hypertension." | 2.53 | Hyperaldosteronism: Screening and Diagnostic Tests. ( Fallo, F; Sabbadin, C, 2016) |
"Primary aldosteronism (PA), characterized by the inappropriate and abnormal adrenal secretion of aldosterone, is the most common cause of secondary hypertension." | 2.53 | Hyperaldosteronism: How to Discriminate Among Different Disease Forms? ( Buffolo, F; Burrello, J; Crudo, V; Monticone, S; Mulatero, P; Tetti, M; Veglio, F, 2016) |
"Pseudohyperaldosteronism is characterized by a clinical picture of hyperaldosteronism with suppression of renin and aldosterone." | 2.53 | Syndromes that Mimic an Excess of Mineralocorticoids. ( Armanini, D; Sabbadin, C, 2016) |
"Obesity is a serious health hazard with rapidly increasing prevalence in the United States." | 2.53 | Obesity, hypertension and aldosterone: is leptin the link? ( Bollag, WB; Xie, D, 2016) |
"Primary aldosteronism (PA) is a condition well worth detecting because it is a common cause of hypertension and is associated with excessive morbidity for the degree of hypertension and reduced quality of life, all of which can be abrogated with specific surgical or medical treatment." | 2.52 | Update in primary aldosteronism. ( Stowasser, M, 2015) |
"A brief introduction to primary aldosteronism is provided." | 2.52 | Laboratory challenges in primary aldosteronism screening and diagnosis. ( Cavalier, E; Don-Wauchope, AC; Holmes, DT; Raizman, JE; Rehan, M, 2015) |
"Hypertension is one of the most common cardiovascular diseases during pregnancy." | 2.52 | [Hypertension in the course of primary aldosteronism during pregnancy]. ( Chudek, J; Maruniak-Chudek, I; Olszanecka-Glinianowicz, M; Sikora, J; Wyskida, K; Wyskida, M, 2015) |
"Primary aldosteronism is one of the commonly identified causes of hypertension and is treatable and/or potentially curable." | 2.52 | Mineralocorticoid and apparent mineralocorticoid syndromes of secondary hypertension. ( Ardhanari, S; Chaudhary, K; Kannuswamy, R; Lockette, W; Whaley-Connell, A, 2015) |
"Obesity is a multifactorial disease associated with hypertension." | 2.52 | Reviving the use of aldosterone inhibitors in treating hypertension in obesity. ( Belin De Chantemèle, EJ; Huby, AC, 2015) |
"Primary aldosteronism, caused by autonomous secretion of aldosterone by the adrenals, is estimated to account for at least 5% of hypertension cases." | 2.52 | Pharmacological treatment of aldosterone excess. ( Deinum, J; Lenders, JW; Riksen, NP, 2015) |
"Primary aldosteronism (PA) is characterized by autonomic aldosterone production, usually leading to severe hypertension and hypokalaemia." | 2.52 | [Primary aldosteronism: new insights into familial forms]. ( Claahsen van der Grinten, HL; Danser, AH; Deinum, J; van den Meiracker, AH; van der Linde, AA, 2015) |
"Obesity is epidemic and is associated with increased blood pressure, which often manifests as treatment-resistant hypertension." | 2.50 | A critical review of the evidence supporting aldosterone in the etiology and its blockade in the treatment of obesity-associated hypertension. ( Brook, RD; Byrd, JB, 2014) |
"Indeed, hypertension is surgically curable in a minority of patients, mostly in patients with aldosterone-secreting adenomas or with pheochromocytomas or functional paragangliomas." | 2.50 | [Presentations and management of adrenal hypertension]. ( Amar, L; Azizi, M; Giavarini, A; Lorthioir, A; Plouin, PF, 2014) |
"Heart failure is a complex syndrome that affects almost all organs and systems of the body." | 2.50 | [Organ damage and cardiorenal syndrome in acute heart failure]. ( Casado Cerrada, J; Pérez Calvo, JI, 2014) |
" The dose-response relationship for natriuresis with spironolactone has not been explored completely as to its combination therapy responses." | 2.50 | Aldosterone and volume management in hypertensive heart disease. ( Sica, DA, 2014) |
"Other than treatment for weight loss, treatment of hypertension with specific antihypertensive medications that block or reduce aldosterone action are appropriate in obese patients." | 2.50 | Increased aldosterone: mechanism of hypertension in obesity. ( Flynn, C, 2014) |
"Hypertension (HTN) and obstructive sleep apnea (OSA) are coexistent in millions of people, and both have been associated with heart disease, stroke, and premature death." | 2.50 | Bidirectional relationship of hypertension with obstructive sleep apnea. ( Jhamb, M; Unruh, M, 2014) |
"Resistant hypertension is a clinically distinct subgroup of hypertension defined by the failure to achieve blood pressure control on optimal dosing of at least 3 antihypertensive medications of different classes, including a diuretic." | 2.50 | Pathophysiology and treatment of resistant hypertension: the role of aldosterone and amiloride-sensitive sodium channels. ( Calhoun, DA; Judd, EK; Warnock, DG, 2014) |
"Hypertension is traditionally considered a disease in which elevated blood pressure contributes to inflammation and activation of the immune system, leading to cardiovascular injury and end-organ damage." | 2.49 | Immune system alterations by aldosterone during hypertension: from clinical observations to genomic and non-genomic mechanisms leading to vascular damage. ( Barake, MF; Campino, C; Fardella, CE; Kalergis, AM; Letelier, NA; Muñoz-Durango, N, 2013) |
"Aldosterone plays a major role in the regulation of sodium and potassium homeostasis and blood pressure." | 2.49 | Genetics of mineralocorticoid excess: an update for clinicians. ( Boulkroun, S; Rickard, AJ; Zennaro, MC, 2013) |
" of public health relevance) on BP and whether there was a dose-response relationship; (2) the effect on BP by sex and ethnic group; (3) the effect on plasma renin activity, aldosterone, noradrenaline, adrenaline, cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and triglycerides." | 2.49 | Effect of longer-term modest salt reduction on blood pressure. ( He, FJ; Li, J; Macgregor, GA, 2013) |
"Aldosterone has been found to be associated with cardiovascular toxicity." | 2.49 | Diagnosis and management of primary aldosteronism: an updated review. ( Chang, CC; Chao, CT; Chueh, SJ; Kuo, CC; Lin, YH; Pimenta, E; Stowasser, M; Wu, KD; Wu, VC, 2013) |
"Aldosterone is a downstream effector of angiotensin II in the renin-angiotensin-aldosterone system and binds to the mineralocorticoid receptor." | 2.49 | Aldosterone receptor antagonists: current perspectives and therapies. ( Ahmed, MI; Calhoun, DA; Clark, D; Guichard, JL, 2013) |
"Hypertension is an established risk factor for stroke, premature coronary artery disease and heart failure." | 2.49 | Aldosterone synthase inhibition in hypertension. ( Andersen, K, 2013) |
"The identification of primary aldosteronism as a common cause of resistant hypertension is a significant advance in our ability to care for patients with hypertension." | 2.49 | Endocrine and hypertensive disorders of potassium regulation: primary aldosteronism. ( Weiner, ID, 2013) |
"Primary aldosteronism (PA) is now recognized as the most frequent form of secondary arterial hypertension." | 2.49 | Diagnosis and treatment of unilateral forms of primary aldosteronism. ( Burrello, J; Crudo, V; Galmozzi, M; Loiacono, M; Monticone, S; Mulatero, P; Tizzani, D; Veglio, F; Versace, K; Viola, A, 2013) |
"Primary aldosteronism (PA) seems to be a pathogenetically heterogenous disease." | 2.49 | Primary aldosteronism: a new insight into pathogenesis, diagnosis, and treatment in hypertensive patients. ( Hyla-Klekot, L; Kokot, F, 2013) |
" An 8-week placebo-controlled dose-response study on patients with Stage 1 and 2 essential hypertension reported an optimal decrease in BP with a dose of 1 mg LCI699 q." | 2.49 | Aldosterone synthase inhibition in humans. ( Amar, L; Azizi, M; Menard, J, 2013) |
"Primary aldosteronism (PA) has a prevalence in the general hypertensive population from 5 to 10%, and is widely recognized as the most frequent form of secondary hypertension." | 2.48 | Primary aldosteronism: who should be screened? ( Burrello, J; Crudo, V; Galmozzi, M; Monticone, S; Mulatero, P; Tizzani, D; Veglio, F; Viola, A, 2012) |
"The MR-associated hypertension is classified into two subtypes, that with elevated plasma aldosterone levels and that with normal plasma aldosterone levels." | 2.48 | Mineralocorticoid receptor-associated hypertension and its organ damage: clinical relevance for resistant hypertension. ( Itoh, H; Shibata, H, 2012) |
"A close association exists between hyperaldosteronism, RHTN, and obstructive sleep apnea (OSA) based upon recent studies which indicate that OSA is worsened by aldosterone-mediated fluid retention." | 2.48 | Resistant hypertension and aldosterone: an update. ( Ahmed, MI; Calhoun, DA; Clark, D, 2012) |
" The observation of reduced nitric oxide bioavailability in hyperaldosteronism implied the generation of oxidative stress by aldosterone." | 2.48 | Aldosterone, oxidative stress, and NF-κB activation in hypertension-related cardiovascular and renal diseases. ( Queisser, N; Schupp, N, 2012) |
"Addition of MR antagonists to standard treatment for hypertension and cardiac or renal disease decreases end-organ pathology and sympathetic nerve activation (SNA), and increases quality of life indices." | 2.48 | The ubiquitous mineralocorticoid receptor: clinical implications. ( Gomez-Sanchez, CE; Gomez-Sanchez, CM; Gomez-Sanchez, EP; Hawkins, UA, 2012) |
"Endocrine hypertension is the most common cause of secondary hypertension affecting ~3 % of the population, with primary hyperaldosteronism and pheochromocytoma being the principal conditions." | 2.48 | [Update on endocrine hypertension]. ( Al-Salameh, A; Chanson, P; Cohen, R; Plouin, PF, 2012) |
"Primary hyperaldosteronism (PHA) is characterized by an increased Aldosterone synthesis which is independent of the Renin-Angiotensin-Aldosterone-System (RAAS)." | 2.48 | [Primay hyperaldosteronism--diagnostic and treatment]. ( Beuschlein, F; Potthoff, SA; Vonend, O, 2012) |
"Patients with treatment-resistant hypertension usually have OSA and have had a good antihypertensive response to spironolactone." | 2.47 | Antihypertensive therapy for patients with obstructive sleep apnea. ( Milic, M; Sun, P; Ziegler, MG, 2011) |
"Aldosterone antagonists have been highly successful in treating congestive heart failure and resistant hypertension." | 2.47 | Mineralocorticoid receptor blockade in chronic kidney disease. ( Bomback, AS; Klemmer, PJ; Volk, MJ, 2011) |
"Conversely, hypothyroidism is accompanied by a marked decrease in sensitivity to sympathetic agonists with an increase of peripheral vascular resistance and arterial stiffness." | 2.47 | Arterial hypertension and thyroid disorders: what is important to know in clinical practice? ( Al-Nahhas, A; Armigliato, M; Beltramello, G; Grassetto, G; Marzola, MC; Mazza, A; Montemurro, D; Rampin, L; Rubello, D; Zorzan, S; Zuin, M, 2011) |
"In the setting of primary aldosteronism, elevated aldosterone levels are associated with increased blood pressure." | 2.46 | Aldosterone and arterial hypertension. ( Obermayer-Pietsch, B; Pieber, TR; Pilz, S; Ritz, E; Tomaschitz, A, 2010) |
"Aldosterone was in the past considered only as a prohypertensinogenic agent." | 2.46 | Aldosterone in uremia - beyond blood pressure. ( Koleganova, N; Ritz, E, 2010) |
"Obesity is a major risk factor for the development of hypertension." | 2.46 | Drug mechanisms to help in managing resistant hypertension in obesity. ( Danser, JA; Jansen, PM; Spiering, W; van den Meiracker, AH, 2010) |
"Primary aldosteronism (PA) is a common cause of arterial hypertension: in the PA Prevalence in Hypertensives (PAPY) Study, the prevalence of PA was 11." | 2.46 | Prevalence and diagnosis of primary aldosteronism. ( Rossi, GP, 2010) |
"Primary aldosteronism (PA) is one of the common forms of curable hypertension." | 2.46 | Cardiovascular and renal damage in primary aldosteronism: outcomes after treatment. ( Catena, C; Colussi, G; Di Fabio, A; Sechi, LA, 2010) |
"Low-renin hypertension is a common type of resistant hypertension and is often associated with increased sodium retention." | 2.45 | Molecular and clinical investigations in patients with low-renin hypertension. ( Brown, MJ; Mackenzie, IS, 2009) |
"Aldosterone plays an important role in electrolyte and blood pressure homeostasis." | 2.45 | Altered corticosteroid biosynthesis in essential hypertension: A digenic phenomenon. ( Alvarez-Madrazo, S; Connell, JM; Davies, E; Fraser, R; Freel, EM; Mackenzie, SM, 2009) |
"Aldosterone is an adrenal hormone that regulates sodium, fluid, and potassium balance." | 2.45 | Aldosterone and cardiovascular disease. ( Calhoun, DA; Gaddam, KK; Husain, S; Pimenta, E, 2009) |
"Primary hyperaldosteronism is a growing cause of apparently essential hypertension (until 15 % of patients with hypertension)." | 2.45 | [Primary hyperaldosteronisms: from diagnosis to treatment]. ( Carnaille, B; Douillard, C; Mounier-Vehier, C; Wémeau, JL, 2009) |
"Eplerenone has been reported to have anti-hypertensive and protective effects on cardiovascular and renal injury in salt-sensitive hypertensive animal models, such as the Dahl salt-sensitive (DS) hypertensive rat and leptin receptor-deficient spontaneously hypertensive rat (SHR/cp)." | 2.45 | Effects of eplerenone, a selective mineralocorticoid receptor antagonist, on clinical and experimental salt-sensitive hypertension. ( Takeda, Y, 2009) |
"Aldosterone has been found to accelerate the increase in left ventricular mass in patients with hypertension." | 2.45 | Resistant hypertension: who and how to evaluate. ( Acelajado, MC; Calhoun, DA, 2009) |
"Aliskiren is a new renin inhibitor that block the RAAS at its origin." | 2.45 | Aliskiren: a new inhibitor of renin-angiotensin aldosterone system activity. ( Dalla Vestra, M; Masiero, A; Simioni, N, 2009) |
"Primary aldosteronism is the most common cause of mineralocorticoid-induced hypertension, and MR antagonism offers the best prospect for achieving therapeutic goals." | 2.44 | Mineralocorticoid antagonism and cardiac hypertrophy. ( Nagata, K, 2008) |
"Features of visceral obesity and obstructive sleep apnea that may stimulate aldosterone secretion are described here." | 2.44 | Obesity, sleep apnea, aldosterone, and hypertension. ( Goodfriend, TL, 2008) |
"Primary aldosteronism (PA) is a known cause of hypertension." | 2.44 | [Primary aldosteronism]. ( Carvajal, CA; Fardella, CE; Mosso, LM, 2008) |
"Aldosterone has also been demonstrated to be a major factor in target organ damage independent of its effects on blood pressure." | 2.44 | Aldosterone as an independent factor in cerebrovascular damage. ( Bertello, C; Caserta, M; Giraudo, G; Morello, F; Mulatero, P; Schiavone, D; Veglio, F; Verhovez, A, 2008) |
" Although the exact incidence of resistant hypertension is not established, estimates derived from recent outcome studies including the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT), Valsartan Antihypertensive Long-term Use Evaluation (VALUE), and Controlled Onset Verapamil Investigation of Cardiovascular End Points (CONVINCE) emphasize that this condition may be more common than previously thought." | 2.44 | Resistant hypertension: prevalence and evolving concepts. ( Epstein, M, 2007) |
"Aldosterone has also been shown to exert a number of effects in the central nervous system." | 2.44 | Aldosterone and the vasculature: mechanisms mediating resistant hypertension. ( Duprez, DA, 2007) |
"Primary hyperaldosteronism is the most common secondary form of hypertension." | 2.44 | [Diagnosis of primary hyperaldosteronism]. ( Bidlingmaier, M; Diederich, S; Quinkler, M; Reincke, M, 2007) |
"Human hypertension affects affects more than 20% of the adult population in industrialized countries, and it is implicated in millions of deaths worldwide each year from stroke, heart failure and ischemic heart disease." | 2.44 | Genetics of arterial hypertension and hypotension. ( Rimmbach, C; Rosskopf, D; Schäfers, R; Schürks, M, 2007) |
"More than 80% of patients with type 2 diabetes mellitus develop hypertension, and approx." | 2.44 | Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions. ( Savoia, C; Schiffrin, EL, 2007) |
" Moreover, ACE gene polymorphisms contribute to the modulation and adequacy of the neurohormonal response to long-term ACE inhibition, at least in patients with CHF (up to 45% of CHF patients have elevated Ang II levels despite the long-term use of an ACEI) or diabetes." | 2.44 | Angiotensin II reactivation and aldosterone escape phenomena in renin-angiotensin-aldosterone system blockade: is oral renin inhibition the solution? ( Athyros, VG; Kakafika, AI; Karagiannis, A; Mikhailidis, DP; Tziomalos, K, 2007) |
"Aldosterone is an important mediator in the pathogenesis of heart failure, and increased plasma aldosterone levels are associated with a poor prognosis." | 2.44 | Drug insight: aldosterone-receptor antagonists in heart failure--the journey continues. ( Francis, GS; Kalidindi, SR; Tang, WH, 2007) |
"Primary aldosteronism has been shown to represent 8-13% (rather than <1%) of unselected hypertensive patients, and patients with primary aldosteronism to have higher indices of cardiovascular damage than controls of the same age, sex, and BP status." | 2.44 | The role of aldosterone and mineralocorticoid receptors in cardiovascular disease. ( Funder, JW, 2007) |
"Overweight and obesity are associated with arterial hypertension." | 2.44 | The association of aldosterone with obesity-related hypertension and the metabolic syndrome. ( Bochud, M; Burnier, M; Vogt, B, 2007) |
"Primary aldosteronism is a relatively common form of secondary hypertension -- affecting 5 to 10% of all patients with hypertension." | 2.44 | Adrenal causes of hypertension: pheochromocytoma and primary aldosteronism. ( Young, WF, 2007) |
"Individuals with primary aldosteronism make up a substantial proportion of those with hypertension." | 2.44 | Hyperaldosteronism: a commonly occurring underlying feature of essential hypertension and the metabolic syndrome? ( Chun, TY; Pratt, JH, 2007) |
"The syndrome of primary aldosteronism, however, encompasses a wide spectrum of disorders that will require better definition." | 2.44 | Aldosterone and refractory hypertension. ( Nyirenda, MJ; Padfield, PL, 2007) |
"Aldosterone plays a significant role in the pathogenesis of arterial hypertension and renal disease." | 2.44 | Aldosterone and progression of renal disease. ( Wenzel, U, 2008) |
"Hyperaldosteronism is now recognized as the most common secondary cause and all patients with resistant hypertension should be screened with a plasma aldosterone-renin ratio even if the serum potassium level is normal." | 2.44 | Resistant hypertension and aldosteronism. ( Calhoun, DA; Pimenta, E, 2007) |
"Hypertension is frequently found in endogenous Cushing's Syndrome (CS)." | 2.44 | Endocrine arterial hypertension: diagnostic approach in clinical practice. ( Armigliato, M; Cuppini, S; Mazza, A; Pessina, AC; Rempelou, P; Rubello, D; Zamboni, S; Zennaro, R, 2008) |
"Aldosterone was also involved in the podocyte damage and proteinuria of metabolic syndrome model SHR/NDmcr-cp." | 2.44 | Aldosterone and glomerular podocyte injury. ( Fujita, T; Nagase, M, 2008) |
"Torcetrapib was the first CETP inhibitor to enter a large-scale, prospective, placebo-controlled interventional trial, which was prematurely terminated in December 2006 because of excess cardiovascular and noncardiovascular mortality in the active treatment group." | 2.44 | Spotlight on HDL-raising therapies: insights from the torcetrapib trials. ( Chapman, MJ; Guérin, M; Kontush, A, 2008) |
"Metabolic syndrome is an aggregation of hypertension, diabetes and dyslipidaemia." | 2.44 | Aldosterone in salt-sensitive hypertension and metabolic syndrome. ( Fujita, T, 2008) |
"Obesity is strongly associated with hypertension and cardiovascular disease." | 2.43 | Obesity-associated hypertension: new insights into mechanisms. ( Correia, ML; Haynes, WG; Mark, AL; Rahmouni, K, 2005) |
"Hypertension is a complex genetic disorder caused by interplay between several "risk" genes and environmental factors (genetic heritability approximately 30%)." | 2.43 | Genetics of human hypertension. ( Agarwal, A; Fisher, ND; Williams, GH, 2005) |
"Aldosterone plays an important role in the pathophysiology of sodium/potassium and water homeostasis of the body." | 2.43 | Cardiovascular effects of aldosterone. ( Murin, J, 2005) |
"The use of ARAs for the treatment of myocardial failure and selected cases of hypertension, in combination with the current therapy, has been strongly supported by trials such as the Randomized Aldactone Evaluation Study (RALES) and the Eplerenone Neurohormonal Efficacy and Survival Study (EPHESUS)." | 2.43 | Aldosterone receptor antagonists: biology and novel therapeutic applications. ( Magni, P; Motta, M, 2005) |
"Primary aldosteronism is a rare cause of hypertension." | 2.43 | [Hypertension due to primary aldosteronism]. ( Bovy, C; Delanaye, P; Hamoir, E; Krzesinski, JM; Maweja, S; Radermecker, RP, 2005) |
"Aldosterone plays an important role in the pathogenesis of cardiovascular disease." | 2.43 | Role of cardiovascular aldosterone in hypertension. ( Takeda, Y, 2005) |
"In primary and secondary aldosteronism, aldosterone synthesis continues despite volume expansion and causes hypertension." | 2.43 | Miscellaneous endocrine causes of hypertension. ( Auchus, RJ, 2005) |
"Obesity is strongly associated with arterial hypertension." | 2.43 | Mineralocorticoid-stimulating activity of adipose tissue. ( Bornstein, SR; Ehrhart-Bornstein, M; Lamounier-Zepter, V, 2005) |
"Primary aldosteronism is a much more common cause of secondary hypertension than once suspected, accounting for approximately 10% of cases." | 2.43 | The pharmacological treatment of primary aldosteronism. ( Bouloux, PM; Janmohamed, S, 2006) |
"Hypertension is often associated clinically with diabetes as part of the insulin-resistance syndrome or as a manifestation of renal disease." | 2.43 | Hypertension and diabetes: role of the renin-angiotensin system. ( Cooper, ME; Jandeleit-Dahm, K, 2006) |
"Normokalaemic manifestation of primary aldosteronism is a frequent cause of secondary hypertension." | 2.43 | Screening for primary aldosteronism. ( Reincke, M; Schirpenbach, C, 2006) |
"Surgically correctable forms of primary aldosteronism are generally held to be less common than forms requiring medical therapy." | 2.43 | Surgically correctable hypertension caused by primary aldosteronism. ( Rossi, GP, 2006) |
"Endocrine hypertension is a term used for states in which hormone derangements result in clinically significant hypertension." | 2.43 | Incidentally discovered masses in hypertensive patients. ( Cicala, MV; Mantero, F; Sartorato, P, 2006) |
"Primary aldosteronism (PA) is a form of surgically curable secondary hypertension." | 2.43 | [Screening tests and diagnostic examinations of hypertensives for primary aldosteronism]. ( Nishikawa, T; Omura, M, 2006) |
"Arterial hypertension is one of the major coronary risk factors for cardiovascular diseases." | 2.43 | [Hypertension in postmenopausal women --selected pathomechanisms]. ( Kawecka-Jaszcz, K; Pośnik-Urbańska, A, 2006) |
" Fibrosis of the right ventricle, the atria, and the pulmonary artery supports the concept that these effects are BP independent, corroborated by the finding that spironolactone in a dosage not sufficient to lower BP prevents myocardial fibrosis." | 2.42 | Aldosterone-induced cardiac damage: focus on blood pressure independent effects. ( Schmidt, BM; Schmieder, RE, 2003) |
"Aldosterone has direct effects on the vasculature and has been associated with vascular smooth muscle cell hypertrophy, endothelial dysfunction, cardiac fibrosis, proteinuria, and renal vascular injury." | 2.42 | Aldosterone: a risk factor for vascular disease. ( Fritsch Neves, M; Schiffrin, EL, 2003) |
"These forms of hypertension are rather rare in their complete expression, but they point to candidate genes whose mutations may predispose to hypertension." | 2.42 | [Monogenic hypertension]. ( Bähr, V; Diederich, S; Oelkers, W, 2003) |
"Mineralocorticoid hypertension is the consequence of an overactivity of the epithelial sodium channel expressed at the apical membrane of renal cells in the distal nephron." | 2.42 | Forms of mineralocorticoid hypertension. ( Bonny, O; Ferrari, P, 2003) |
"Primary hyperaldosteronism (PHA), autonomic secretion of aldosterone by the adrenal gland, is rare." | 2.42 | [Primary hyperaldosteronism]. ( Deinum, J; van den Meiracker, AH, 2003) |
"Aldosterone is an important and independent target for therapeutic intervention in hypertension and hypertension-related diseases." | 2.42 | Aldosterone receptor antagonists for hypertension: what do they offer? ( Krum, H; Liew, D, 2003) |
"The classical form of primary aldosteronism is a rare disease with prevalence rates of 0." | 2.42 | [The aldosterone to Renin ratio in secondary hypertension]. ( Reincke, M; Seiler, L, 2003) |
"Hypertension is an important determinant of heart failure." | 2.42 | A neuroendocrine-immune interface. The immunostimulatory state of aldosteronism. ( Weber, KT, 2003) |
"Obesity is a common problem in much of the western world today in that is linked directly with several disease processes, notably, hypertension." | 2.42 | Hypertension and obesity. ( Aneja, A; El-Atat, F; McFarlane, SI; Sowers, JR, 2004) |
"Obesity has become an epidemic problem in western societies, contributing to metabolic diseases, hypertension and cardiovascular disease." | 2.42 | Mechanisms of obesity-related hypertension. ( Bornstein, SR; Ehrhart-Bornstein, M; Lamounier-Zepter, V, 2004) |
" It is, therefore, not surprising that this analysis showed a small fall in blood pressure, and that a dose-response to salt reduction was not demonstrable." | 2.42 | Effect of longer-term modest salt reduction on blood pressure. ( He, FJ; MacGregor, GA, 2004) |
"Aldosterone plays an important role in the pathogenesis of cardiovascular and renal disease that is independent of angiotensin II." | 2.42 | Pleiotropic actions of aldosterone and the effects of eplerenone, a selective mineralocorticoid receptor antagonist. ( Takeda, Y, 2004) |
"Aldosterone has been only considered as a humoral factor playing a role in salt and water homeostasis and as a consequence controlling arterial blood pressure." | 2.41 | [Aldosterone and cardiovascular diseases, more than water and salt retention]. ( Duprez, D, 2002) |
"Primary aldosteronism is a disorder characterized by hypertension and, in more severe form, hypokalemia, due to autonomous aldosterone secretion from the adrenocortical zona glomerulosa." | 2.41 | New genetic insights in familial hyperaldosteronism. ( Jackson, RV; Lafferty, A; Stratakis, C; Torpy, DJ, 2002) |
"The two major subtypes of primary aldosteronism are unilateral aldosterone-producing adenoma (APA) and bilateral idiopathic hyperplasia (IHA)." | 2.41 | Primary aldosteronism: management issues. ( Young, WF, 2002) |
"Hypertension is a major risk factor for progressive renal disease." | 2.41 | Aldosterone and the hypertensive kidney: its emerging role as a mediator of progressive renal dysfunction: a paradigm shift. ( Epstein, M, 2001) |
"Aldosterone has been identified as a critically important neurohormone with direct detrimental effects on the myocardium." | 2.41 | Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure. ( Miller, AB; Srivastava, P, 2001) |
"When primary aldosteronism is diagnosed, fewer than one-third of patients are suitable for surgery as initial treatment, but this still represents a significant percentage of hypertensive patients." | 2.41 | Primary aldosteronism: are we diagnosing and operating on too few patients? ( Gordon, RD; Rutherford, JC; Stowasser, M, 2001) |
"Primary aldosterone excess or hyperaldosteronism is an important cause of hypertension which, when associated with an aldosterone secreting adenoma, is amenable to surgical cure." | 2.41 | Primary aldosteronism, a common entity? the myth persists. ( Padfield, PL, 2002) |
"2." | 2.41 | Familial varieties of primary aldosteronism. ( Gordon, RD; Gunasekera, TG; Stowasser, M, 2001) |
"The role of left ventricular hypertrophy as an independent risk factor for subsequent cardio-vascular events is well established, therefore the authors, in this brief review, describe the endocrine function of the heart and the role played by various factors, including hormones, in the development of cardiac remodeling during the course of hypertension." | 2.40 | [Pathophysiology of left ventricular hypertrophy in arterial hypertension]. ( Braconi-Quintaje, S; Lang, U; Vallotton, MB, 1997) |
"The syndrome is due to a deficiency of the renal enzyme 11-beta-hydroxysteroid dehydrogenase type II, which protects the mineralocorticoid receptor against cortisol that binds to the mineralocorticoid receptor like aldosterone." | 2.40 | [Mineralocorticoid-induced hypertension]. ( Hensen, J; Oelkers, W, 1997) |
"Among these, classic primary hyperaldosteronism and its glucocorticoid remediable variety, in which hypertension is secondary to aldosterone production, must be considered." | 2.40 | [Hypertension and mineralocorticoids. Usefulness of renin and aldosterone measurements]. ( Fardella, CE; Montero, J; Mosso, L, 1999) |
"We report a rare case of primary hyperaldosteronism due to a unilateral adrenal cortical adenoma in an 11-year-old female patient." | 2.39 | Aldosterone-secreting adrenal cortical adenoma in an 11-year-old child and collective review of the literature. ( Chi, CS; Li, JT; Shu, SG, 1994) |
"Glucocorticoid-remediable aldosteronism (GRA) is an autosomal-dominant form of human hypertension." | 2.39 | Glucocorticoid-remediable aldosteronism. ( Dluhy, RG; Lifton, RP, 1994) |
"Hyperaldosteronism owing to aldosterone-producing adenoma (Conn syndrome) is a rare but potentially curable form of pediatric hypertension." | 2.39 | Conn syndrome in a child, caused by adrenal adenoma. ( Abasiyanik, A; Calişkan, U; Erkul, I; Kaymakçi, A; Oran, B; Yaşar, C, 1996) |
"Enalapril maleate is a prodrug which when administered orally is hydrolysed to release the active converting enzyme inhibitor enalaprilat." | 2.37 | An overview of the clinical pharmacology of enalapril. ( Davies, RO; Gomez, HJ; Irvin, JD; Walker, JF, 1984) |
"When used in congestive heart failure, ACE inhibitors exert a balanced vasodilator effect on arterial and venous beds and do not induce tachycardia or fluid retention." | 2.37 | Overview: the role of angiotensin-converting enzyme inhibitors in cardiovascular therapy. ( Abrams, WB; Davies, RO; Ferguson, RK, 1984) |
"Aldosterone hypertension was a typical volume loading type with sodium retention, increased blood volume and extracellular fluid volume and a slow rise in arterial pressure." | 2.37 | Interaction between the natriuretic effects of renal perfusion pressure and the antinatriuretic effects of angiotensin and aldosterone in control of sodium excretion. ( Pan, YJ; Young, DB, 1984) |
"In patients with congestive heart failure treated with digitalis, these natriuretic agents are particularly useful because of their potassium-sparing properties." | 2.37 | Clinical applications of antimineralocorticoids. ( Brunner, HR; Nüssberger, J; Waeber, B, 1988) |
" Suitable techniques for the investigation of secondary aldosteronism of unknown cause and for primary and secondary hypoaldosteronism are described, as well as the adjustment of dosage for replacement therapy where mineralocorticoid secretion is deficient." | 2.37 | Disorders of mineralocorticoid activity. ( Drury, PL, 1985) |
"Severe hypertension is more likely to occur in the predisposed, and malignant hypertension has been reported." | 2.35 | Drug-induced hypertension: pathogenesis and management. ( Stokes, GS, 1976) |
"Usually hypertension is reversible after cessation of therapy with contraceptive steroids." | 2.35 | [Clinical aspects of hypertension under contraceptive steroids]. ( Kaulhausen, H; Klingsiek, L, 1976) |
"Hypertension is common in patients with type 2 diabetes who carry increased cardiovascular risk; however, it is unknown how frequently they are tested for PA." | 1.91 | Screening for primary aldosteronism in the diabetic population: a cohort study. ( Libianto, R; Tan, SJ; Wong, J; Yang, J, 2023) |
"Bilateral idiopathic hyperaldosteronism (IHA) is responsible for 60% of primary aldosteronism (PA) cases." | 1.91 | Unilateral Adrenalectomy for Primary Aldosteronism Due to Bilateral Adrenal Disease Can Result in Resolution of Hypokalemia and Amelioration of Hypertension. ( Bancos, I; Dy, BM; Foster, TR; Lyden, ML; McKenzie, TJ; Shariq, OA; Szabo Yamashita, T; Young, WF, 2023) |
"According to the primary aldosteronism surgical outcome (PASO) criteria, complete and partial clinical success was achieved in 21 (40." | 1.91 | Catheter-based adrenal ablation: an alternative therapy for patients with aldosterone-producing adenoma. ( He, H; Jiang, J; Li, Q; Li, Y; Liu, X; Sun, F; Yan, Z; Zhang, H; Zhao, Z; Zhou, X; Zhu, Z, 2023) |
"Primary aldosteronism (PA) patients have a higher degree of arterial stiffness, which can be reversed after adrenalectomy." | 1.91 | Implication of MR Activity in Posttreatment Arterial Stiffness Reversal in Patients With Primary Aldosteronism. ( Chang, CC; Chang, YY; Chen, ZW; Chiu, YW; Chueh, JS; Huang, WC; Hung, CS; Lee, BC; Liao, CW; Lin, YH; Lu, CC; Pan, CT; Tsai, CH; Wang, SM; Wu, VC, 2023) |
"Primary Aldosteronism (PA) is increasingly considered as a common disease affecting up to 10% of the hypertensive population." | 1.91 | Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy. ( Bouhanick, B; Boulestreau, R; Costa, N; Cremer, A; Delchier, MC; Gombault-Datzenko, E; Gosse, P; Lagarde, S; Lepage, B; Molinier, L; Mounie, M; Papadopoulos, P; Rousseau, H; Trillaud, H, 2023) |
"Primary aldosteronism (PA) screening relies on an elevated aldosterone to renin ratio with a minimum aldosterone level, which varies from 10 to 15 ng/dL (277-415." | 1.91 | Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening. ( Almeida, MQ; Bortolotto, LA; Brito, LP; Carnevale, FC; Cavalcante, ACBS; Chambo, JL; Coelho, FMA; Consolim-Colombo, FM; Drager, LF; Fagundes, GFC; Fragoso, MCBV; Freitas, TC; Goldbaum, TS; Latronico, AC; Ledesma, FL; Maciel, AAW; Mendonca, BB; Pereira, MAA; Petenuci, J; Pilan, B; Pio-Abreu, A; Silveira, JV; Srougi, V; Tanno, FY; Vilela, LAP; Zerbini, MCN, 2023) |
"After genetic analysis, a diagnosis of Liddle syndrome was made due to the presence of a p." | 1.91 | A case report of a young boy with low renin and high aldosterone levels induced by Liddle syndrome who was previously misdiagnosed with primary aldosteronism. ( Jin, Y; Qiu, W; Yao, J, 2023) |
"Primary hyperaldosteronism is a major cause of secondary hypertension and carries additional cardiovascular risks beyond that of the elevated blood pressure." | 1.91 | Fatty acids as a direct regulator of aldosterone hypersecretion. ( Albert, SG; Bruno, J; Dhindsa, S; Ling, G, 2023) |
"Aldosterone has hypertrophic and profibrotic effects on the heart." | 1.91 | Serum aldosterone effect on left ventricular structure and diastolic function in essential hypertension. ( Al-Hashedi, EM; Juvenal, H; Mohammed, AA; Yu, J; Zhao, X, 2023) |
"Aldosterone concentration was significantly higher in OC users than nonusers at 17 years (median 486 pmol/L vs 347 pmol/L, P < 0." | 1.91 | Effect of Oral Contraception on Screening Tests for Primary Aldosteronism: A 10-Year Longitudinal Study. ( Beilin, LJ; Fuller, PJ; Gwini, SM; Mori, TA; Schlaich, M; Stowasser, M; Yang, J; Young, MJ, 2023) |
"Primary aldosteronism (PA) is the most common form of secondary hypertension, with its main manifestations including hypertension and hypokalemia." | 1.91 | Advances in Medical Treatment of Primary Aldosteronism. ( Ji, ZG; Li, YJ; Wen, J, 2023) |
"The elevated aldosterone in primary aldosteronism (PA) is associated with increased insulin resistance and prevalence of diabetes mellitus (DM)." | 1.91 | Diabetes mellitus is associated with more adverse non-hemodynamic left ventricular remodeling and less recovery in patients with primary aldosteronism. ( Chang, CC; Chang, YR; Chang, YY; Chen, UL; Chueh, JS; Huang, KH; Hung, CS; Lai, TS; Lee, BC; Liao, CW; Lin, YH; Lu, CC; Tsai, CH; Wang, SM; Wu, VC, 2023) |
"Primary aldosteronism (PA) was suspected because of the high plasma aldosterone concentration-to-plasma renin activity ratio." | 1.91 | Coexistence of Pheochromocytoma and Primary Aldosteronism due to Multiple Aldosterone-producing Micronodules in the Ipsilateral Adrenal Gland. ( Fujita, Y; Hino, M; Horikawa, O; Inoue, K; Kageyama, S; Kawauchi, A; Maegawa, H; Nakaizumi, N; Noujima, M; Sasano, H; Sato, D; Ugi, S; Wada, A; Yamazaki, Y; Yonishi, M, 2023) |
"Primary aldosteronism (PA) is one of the most frequent causes of secondary hypertension." | 1.91 | International multicenter survey on screening and confirmatory testing in primary aldosteronism. ( Azizan, EABA; Beuschlein, F; Ceccato, F; Dalmazi, GD; Deinum, J; Furnica, RM; Gallego, NV; Gruber, S; Grytaas, MA; Kalugina, V; Kastelan, D; Katabami, T; Kobayashi, H; Kocjan, T; Kraljevic, I; Kürzinger, L; Lacroix, A; Laycock, K; Maiolino, G; Markou, A; Murakami, M; Naruse, M; Nijhoff, MF; O'Toole, S; Parasiliti-Caprino, M; Piaditis, G; Puar, T; Quinkler, M; Ragnarsson, O; St-Jean, M; Sukor, N; Suzuki, T; Tanabe, A; Tong, CV; Torre, EM; Tsuiki, M; Wada, N, 2023) |
"Primary aldosteronism is the most frequent secondary hypertensive disease and is characterized by an elevated risk for cardiovascular disease." | 1.91 | Effect of the interaction between the visceral-to-subcutaneous fat ratio and aldosterone on cardiac function in patients with primary aldosteronism. ( Fujiwara, A; Haruna, A; Haze, T; Hirawa, N; Kawano, R; Kobayashi, Y; Ohki, Y; Ozawa, M; Saka, S; Suzuki, S; Tamura, K, 2023) |
"Aldosterone was significantly associated with all-cause mortality (hazard ratio per standard deviation increase: 1." | 1.91 | Association of Aldosterone with Mortality in the General Population. ( Bidlingmaier, M; Heier, M; Herder, C; Koenig, W; Meisinger, C; Peters, A; Rathmann, W; Reincke, M; Roden, M; Seissler, J; Sujana, C; Then, C; Thorand, B, 2023) |
"Primary aldosteronism (PA) is a common cause of secondary hypertension, whereas pheochromocytoma is a rare cause of it." | 1.91 | Pitfalls in the diagnosis and treatment of a hypertensive patient with unilateral primary aldosteronism and contralateral pheochromocytoma: a case report. ( Asayama, Y; Daa, T; Fujinami, H; Gotoh, K; Masaki, T; Miyamoto, S; Nishida, H; Okamoto, M; Ozeki, Y; Shibata, H; Shin, T; Yoshida, Y, 2023) |
"Primary aldosteronism (PA), characterised by low-renin hypertension, confers a high cardiovascular risk and is the most common cause of secondary hypertension, with an increased prevalence in patients with treatment-resistant hypertension." | 1.91 | RAS-challenge as a first-look test for detection of primary aldosteronism in patients with treatment-resistant hypertension. ( Beger, C; Haller, H; Hinrichs, JB; Karg, T; Limbourg, FP; Meyer, BC; Ringe, B, 2023) |
"RRBP1 deficiency in mice caused hyporeninemic hypoaldosteronism, resulting in lower blood pressure, severe hyperkalemia, and sudden cardiac death." | 1.91 | ER ribosomal-binding protein 1 regulates blood pressure and potassium homeostasis by modulating intracellular renin trafficking. ( Chang, YC; Chiu, CH; Chuang, GT; Chuang, LM; Fong, SW; Hee, SW; Hsieh, ML; Hsieh, PC; Hsu, CN; Hsuan, CF; Hung, YJ; Hwu, CM; Lee, HL; Li, WY; Lin, JW; Lin, SH; Lin, SW; Lin, WC; Wu, VC; Yang, WS, 2023) |
"Women exposed to preeclampsia have a substantially increased risk of hypertension after pregnancy, but the mechanism remains unknown, leaving a missed interventional opportunity." | 1.91 | Smooth Muscle Mineralocorticoid Receptor Promotes Hypertension After Preeclampsia. ( Biwer, LA; Camarda, ND; Carvajal, BV; Ibarrola, J; Jaffe, IZ; Karumanchi, SA; Lu, Q; Man, JJ; Seely, EW; Skurnik, G; Stepanian, A; Zsengeller, Z, 2023) |
"Hypertension plus obstructive sleep apnea (OSA) is recommended in some guidelines as an indication to screen for primary aldosteronism (PA), yet prior data has brought the validity of this recommendation into question." | 1.91 | Screening for Primary Aldosteronism Among Hypertensive Adults with Obstructive Sleep Apnea: A Retrospective Population-Based Study. ( Agharazii, M; Goupil, R; Hundemer, GL; Imsirovic, H; Kendzerska, T; Kline, GA; Knoll, G; Leung, AA; Madore, F; Sood, MM; Vaidya, A, 2023) |
"Aldosterone was eventually isolated and identified in the fraction and was soon shown to cause hypertension when in excess." | 1.91 | An Abbreviated History of Aldosterone Metabolism, Current and Future Challenges. ( Gomez-Sanchez, CE; Gomez-Sanchez, EP, 2023) |
"Primary aldosteronism (PA) is a typical example of low renin hypertension, whereas renal artery stenosis (RAS) is a classic form of high renin hypertension." | 1.91 | Renal Artery Stenosis Complicated with Primary Aldosteronism. ( Bao, M; Li, J, 2023) |
"In aldosterone-treated rats compared with control rats, switching from a low-salt diet to a high-salt diet initiated significantly greater increases in mean arterial pressure and SVR and significantly greater decreases in heart rate and CO." | 1.91 | Hypertension in Primary Aldosteronism Is Initiated by Salt-Induced Increases in Vascular Resistance With Reductions in Cardiac Output. ( DiCarlo, SE; Kurtz, TW; Lujan, HL; Morris, RC; Pravenec, M, 2023) |
"In this setting, primary aldosteronism (PA) is a frequent cause of RH and its prevalence in RH patients is likely higher than 20%." | 1.91 | Primary Aldosteronism and Drug Resistant Hypertension: A "Chicken-Egg" Story. ( Lenzini, L; Pintus, G; Rossi, GP; Rossitto, G; Seccia, TM, 2023) |
"Primary hyperaldosteronism is the most common cause of secondary hypertension." | 1.91 | [Adrenalectomy for primary hyperaldosteronism : retrospective review of 57 patients in CHU of Liege]. ( Hamoir, E; Wilmont, E, 2023) |
"Primary aldosteronism (PA) is considered the number one aetiology for secondary hypertension." | 1.91 | Duplicated adrenal veins in primary aldosteronism misdiagnosed with ectopic aldosteronoma due to apparent bilateral aldosterone suppression. ( Chen, K; Fan, C; Fang, T; Liu, H; Quan, H; Wei, W; Yu, J; Zhang, Y, 2023) |
"Patients with primary aldosteronism (PA) have a higher risk of cardiovascular disease (CVD) than essential hypertension due to underlying hyperaldosteronism." | 1.91 | High plasma aldosterone concentration is associated with worse 24-h ambulatory blood pressure profile in patients with primary aldosteronism. ( Azushima, K; Haze, T; Kanaoka, T; Kinguchi, S; Kobayashi, K; Kobayashi, R; Morita, R; Sunohara, S; Tamura, K; Toya, Y; Wakui, H, 2023) |
"Primary aldosteronism (PA) is the most common cause of endocrine hypertension." | 1.91 | Biochemical Evaluation by Confirmatory Tests after Unilateral Adrenalectomy for Primary Aldosteronism. ( Asari, Y; Daimon, M; Kageyama, K; Kinoshita, N; Murasawa, S; Nakada, Y; Takayasu, S; Usutani, M; Watanuki, Y, 2023) |
"Data from the Taiwan Primary Aldosteronism Investigation Group database were analyzed, including patients with unilateral PA who had adrenalectomy between December 2015 and October 2018." | 1.91 | Association of urinary liver-type fatty acid-binding protein with outcomes after adrenalectomy for unilateral primary aldosteronism. ( Chen, CH; Chuang, YW; Lin, YH; Shiao, CC; Wu, CY; Wu, JT; Wu, MJ; Wu, VC; Yu, TM, 2023) |
"Renal cysts were identified using contrast-enhanced computed tomography." | 1.91 | Non-suppression of renin by renal cysts in a subset of patients with primary aldosteronism-a prospective observational single center study. ( Hämäläinen, E; Hinkka, T; Huhtala, H; Matikainen, N; Nevalainen, PI; Nevalainen, R; Niemelä, O; Pörsti, I; Ylänen, A, 2023) |
"Primary aldosteronism was diagnosed based on 4 h PAC, adrenal imaging and/or adrenal venous sampling (AVS)." | 1.91 | Using plasma aldosterone concentrations at 1 h of saline infusion test for the diagnosis of primary aldosteronism. ( Chanthanuwat, S; Jannoo, S; Phonanuwong, R; Soonthornpun, S, 2023) |
"However, obesity has an independent deleterious impact on improvement in blood pressure post-adrenalectomy for PA." | 1.91 | The Impact of Obesity on the Resolution of Hypertension Following Adrenalectomy for Primary Hyperaldosteronism. ( Chidambaram, S; Damji, S; Di Marco, AN; Meeran, K; Palazzo, F; Todd, J; Van Den Heede, K; Wernig, F, 2023) |
"Screening test results for primary aldosteronism were positive for about one-quarter of urban Indigenous and non-Indigenous participants." | 1.91 | Aldosterone and renin concentrations and blood pressure in young Indigenous and non-Indigenous adults in the Northern Territory: a cross-sectional study. ( Fuller, PJ; Gwini, SM; Ng, E; Singh, GR; Stowasser, M; Yang, J; Young, MJ, 2023) |
"Primary aldosteronism (PA) is a well-known cause of secondary hypertension." | 1.91 | Simple standing test without furosemide is useful in the diagnosis of primary aldosteronism. ( Fushimi, Y; Iwamoto, H; Iwamoto, Y; Kaku, K; Kaneto, H; Katakura, Y; Kimura, T; Kusano, T; Mune, T; Nakanishi, S; Ohnishi, M; Sanada, J; Shimoda, M; Takenouchi, H; Tatsumi, F, 2023) |
"Hypertension in CS promotes hypercortisolism-associated cardiovascular events." | 1.91 | Unique Gene Expression Signature in Periadrenal Adipose Tissue Identifies a High Blood Pressure Group in Patients With Cushing Syndrome. ( Caratti, G; Reincke, M; Stifel, U; Tuckermann, J; Vogel, F, 2023) |
""Likely" primary aldosteronism was defined as ARR ≥ 70 pmol/mIU." | 1.91 | Associations Between Aldosterone-Renin-Ratio and Bone Parameters Derived from Peripheral Quantitative Computed Tomography and Impact Microindentation in Men. ( Anderson, KB; Diez-Perez, A; Gwini, SM; Henneberg, M; Holloway-Kew, KL; Hyde, NK; Kotowicz, MA; Liao, WH; Pasco, JA; Rufus-Membere, P; Sui, SX; Tembo, MC; Yang, J, 2023) |
"Primary aldosteronism is the underlying cause of hypertension in primary care settings in approximately 6% of cases, and it is even more common in patients with resistant hypertension." | 1.91 | Primary Aldosteronism. ( Quencer, KB; Rugge, JB; Senashova, O, 2023) |
"Primary aldosteronism (PA) with unilateral adrenal disease can be cured or improved by adrenalectomy." | 1.91 | Surgery based on computed tomography images might be feasible for primary aldosteronism patients with visible unilateral adenoma. ( Dai, J; Fang, C; He, W; Huang, X; Sun, F; Xu, J; Zhao, J, 2023) |
"Newly presenting hypertension is much the same-hold off on first-order antihypertensive(s) and prescribe spironolactone 25 mg/day for 4 weeks." | 1.91 | Who and How Should We Screen for Primary Aldosteronism? ( Funder, JW, 2023) |
"Aldosterone plays a key role in controlling blood pressure (BP) values by maintaining body salt, water, and fluid homeostasis." | 1.91 | Expression of functional mineralocorticoid receptor (MR) and G-protein coupled estrogen receptor (GPER) in human T lymphocytes. ( Caroccia, B; Carraro, S; Piazza, M; Rossi, GP, 2023) |
"Patients with bilateral primary aldosteronism (PA) generally are treated with antihypertensive drugs, but optimal treatment for patients with complications due to refractory hypertension has not been established." | 1.91 | Unilateral adrenalectomy for a drug-resistant bilateral primary aldosteronism with heart failure: pathophysiology and surgical indication. ( Akaihata, H; Hata, J; Honda-Takinami, R; Hoshi, S; Kataoka, M; Kojima, Y; Matsuoka, K; Ogawa, S; Onagi, A; Sato, Y; Tanji, R, 2023) |
"Atypical Liddle syndrome can be easily misdiagnosed due to its clinical phenotypes resembling hyperaldosteronism." | 1.91 | Liddle syndrome presenting with normal aldosterone levels: A case report. ( Pan, R; Wang, R; Zhang, R; Zhang, Y; Zhao, Y, 2023) |
"The left adrenocortical adenoma was removed by robot-assisted laparoscopic resection." | 1.91 | Bilateral co-secretory lesions presenting with coexisting Cushing syndrome and primary aldosteronism: a case report. ( Chen, F; Chen, T; Gao, H; Li, L; Ren, Y; Tian, H, 2023) |
"Aldosterone was associated inversely with urine sodium/creatinine (β: -0." | 1.72 | Correlation between kidney sodium and potassium handling and the renin-angiotensin-aldosterone system in children with hypertensive disorders. ( Perrin, EC; South, AM, 2022) |
"Primary aldosteronism is a common, yet highly underdiagnosed, cause of hypertension that leads to disproportionately high rates of cardiovascular disease." | 1.72 | Screening Rates for Primary Aldosteronism Among Individuals With Hypertension Plus Hypokalemia: A Population-Based Retrospective Cohort Study. ( Agharazii, M; Goupil, R; Hundemer, GL; Imsirovic, H; Knoll, G; Madore, F; Sood, MM; Vaidya, A; Yozamp, N, 2022) |
"In 2017, the Primary Aldosteronism Surgical Outcome (PASO) investigators proposed consensus criteria for clinical and biochemical outcomes." | 1.72 | Prediction of long-term biochemical cure in patients with unilateral primary hyperaldosteronism treated surgically based on the early post-operative plasma aldosterone value. ( Ishihara, Y; Kaneko, H; Kusakabe, T; Nanba, K; Satoh-Asahara, N; Tagami, T; Tsuiki, M; Umakoshi, H; Yasoda, A, 2022) |
" The results of restricted cubic splines showed the dose-response association between increasing PAC, ARR, decreasing serum potassium, and the risk of WMLs." | 1.72 | Plasma aldosterone concentration is associated with white matter lesions in patients with primary aldosteronism. ( Heizhati, M; Li, N; Liu, Y; Luo, Q; Wang, M; Yao, X; Yuan, Y; Zhu, Q, 2022) |
"Only 795 (4." | 1.72 | Screening Rate for Primary Aldosteronism Among Patients With Apparent Treatment-Resistant Hypertension: Retrospective Analysis of Current Practice. ( Tessier, KM; Zekarias, K, 2022) |
"Primary aldosteronism (PA) is the commonest cause of endocrine hypertension ranging from 4." | 1.72 | Enhanced performance of a modified diagnostic test of primary aldosteronism in patients with adrenal adenomas. ( Chrousos, GP; Gravvanis, C; Kaltsas, GA; Kanti, G; Markou, A; Papanastasiou, L; Piaditis, G; Voulgaris, N; Zografos, GN, 2022) |
"We identified patients with aortic dissection and aneurysm with assessed PAC before disease onset from hospital-based electronic database and set as case group." | 1.72 | Higher Plasma Aldosterone Concentrations Are Associated With Elevated Risk of Aortic Dissection and Aneurysm: a Case-Control Study. ( Gan, L; Heizhati, M; Hong, J; Li, N; Lin, M; Luo, Q; Wang, M; Yao, X; Yue, N; Zhang, W; Zhu, Q, 2022) |
"Spironolactone was initiated." | 1.72 | Apparent mineralocorticoid excess: A diagnosis beyond classical causes of severe hypertension in a child. ( Baltu, D; Çelik Ertaş, NB; Duzova, A; Gönç, N; Gulhan, B; Ozcan, HN; Özdemir, G; Ünsal, Y; Utine, E, 2022) |
"Primary aldosteronism represents the most frequent cause of endocrine hypertension." | 1.72 | [Diagnosis and therapy of primary aldosteronism: new aspects]. ( Asbach, E; Reincke, M, 2022) |
"Diagnosis of primary hyperaldosteronism in pregnancy is complicated due to lack of reference ranges for aldosterone, renin and aldosterone-to-renin ratio." | 1.72 | Establishing Reference Ranges for Aldosterone, Renin and Aldosterone-to-Renin Ratio for Women in the Third-Trimester of Pregnancy. ( Grzesiak, M; Horzelski, W; Lewandowski, KC; Lewinski, A; Tadros-Zins, M, 2022) |
"Primary aldosteronism (PA) is the most common and potentially curable endocrine cause of secondary hypertension, and carries a worse prognosis than essential hypertension." | 1.72 | Screening for primary aldosteronism is underutilised in patients with chronic kidney disease. ( Chauhan, K; Fuller, PJ; Hutton, H; Kerr, PG; Libianto, R; Ryan, J; Schachna, E; Wilson, S; Yang, J, 2022) |
"To assess the identification of primary aldosteronism (PA) in newly diagnosed, treatment-naïve patients with hypertension by screening in primary care." | 1.72 | Detecting primary aldosteronism in Australian primary care: a prospective study. ( Fuller, PJ; Gwini, SM; Libianto, R; Nuttall, P; Russell, GM; Shen, J; Stowasser, M; Yang, J; Young, MJ, 2022) |
"Unilateral subtype of primary aldosteronism (PA) is a common surgically curable form of endocrine hypertension." | 1.72 | Machine learning-based models for predicting clinical outcomes after surgery in unilateral primary aldosteronism. ( Fukumoto, T; Ichijo, T; Ishihara, Y; Iwahashi, N; Kaneko, H; Katsuhara, S; Matsuda, Y; Ogata, M; Ogawa, Y; Sakamoto, R; Sakamoto, S; Tagami, T; Terada, E; Umakoshi, H; Wada, N; Watanabe, T; Yokomoto-Umakoshi, M, 2022) |
"Among 43 patients with primary aldosteronism (PA), thirteen APA patients were enrolled in this study." | 1.72 | Early Renin Recovery After Adrenalectomy in Aldosterone-Producing Adenomas: A Prospective Study. ( Antonini, SR; de Castro, M; Elias, J; Elias, PCL; Mermejo, LM; Molina, CAF; Moreira, AC; Muglia, VF; Tucci, S, 2022) |
"Primary aldosteronism (PA) is associated with higher cardiovascular morbidity and mortality rates than essential hypertension." | 1.72 | Japan Endocrine Society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021. ( Hasegawa, T; Hashimoto, S; Haze, T; Ichijo, T; Izawa, S; Katabami, T; Kobayashi, H; Kurihara, I; Naruse, M; Ogawa, Y; Ohno, Y; Oki, Y; Omura, M; Otsuki, M; Rakugi, H; Saiki, A; Sakamoto, R; Satoh, F; Shibata, H; Sone, M; Takahashi, K; Takeda, Y; Tamura, K; Tanabe, A; Tanaka, T; Tsuiki, M; Wada, N; Yamamoto, K; Yoneda, T; Yoshimoto, T, 2022) |
"Aldosterone (ALD) is a steroid hormone secreted by the zona glomerulosa of the adrenal cortex that mainly acts on the kidney to regulate sodium ion and water reabsorption." | 1.72 | Creation of a quick and sensitive fluorescent immunosensor for detecting the mineralocorticoid steroid hormone aldosterone. ( Dong, H; Dong, J; Gomez-Sanchez, CE; Inagaki, T; Jiang, G; Liang, J; Ueda, H; Wang, H; Yi, Z, 2022) |
"Primary aldosteronism (PA) is the most common cause of secondary hypertension, and patients are at an increased risk of atrial fibrillation (AF) and stroke." | 1.72 | Primary Aldosteronism More Prevalent in Patients With Cardioembolic Stroke and Atrial Fibrillation. ( Aw, TC; Chai, SC; Fones, S; Foo, RSY; Lai, J; Mamauag, MJB; Nguyen, V; Ong, L; Puar, TH; Saffari, SE; Tu, TM; Zhang, M, 2022) |
"Primary aldosteronism (PA) and nonclassic apparent mineralocorticoid excess (NCAME) have been recognized as endocrine-related conditions having a broad clinical-biochemical spectrum, spanning from normotension to severe arterial hypertension (AHT)." | 1.72 | Clinical, biochemical, and miRNA profile of subjects with positive screening of primary aldosteronism and nonclassic apparent mineralocorticoid excess. ( Carvajal, CA; Fardella, CE; Pérez, JA; Tapia-Castillo, A, 2022) |
"Patients were screened for primary aldosteronism with the aldosterone-renin ratio and underwent a saline infusion test for diagnostic confirmation." | 1.72 | Prevalence and clinical characteristics of primary aldosteronism in a tertiary-care center in Korea. ( Ha, J; Hong, N; Ku, CR; Lee, CJ; Park, S; Rhee, Y; Yoon, M, 2022) |
"Among those Liddle syndrome patients confirmed by a genetic test, for Test kit A all ARR were screened positive while for test kit B negative." | 1.72 | Liddle syndrome misdiagnosed as primary aldosteronism is caused by inaccurate aldosterone-rennin detection while a novel ( Chen, L; Qu, D; Sun, Q; Wu, C; Xu, X; Yang, Y; Zhao, X, 2022) |
"Ambulatory FST is safe and accurate and can be performed with significantly less healthcare costs compared to FSTin." | 1.72 | Ambulatory fludrocortisone suppression test in the diagnosis of primary aldosteronism: Safety, accuracy and cost-effectiveness. ( Avander, K; Calissendorff, J; Carasel, A; Falhammar, H; Shabo, I; Volpe, C, 2022) |
"Background Primary aldosteronism can cause cardiac dysfunction, including left ventricular hypertrophy, left ventricular diastolic dysfunction, and left atrial enlargement." | 1.72 | Comparison of Echocardiographic Changes Between Surgery and Medication Treatment in Patients With Primary Aldosteronism. ( Hoshino, Y; Inoue, K; Nakai, K; Nishikawa, T; Ono, M; Osada, J; Saito, J; Tsurutani, Y; Ueda, T; Yumoto, K, 2022) |
"The aldosterone/renin ratio was proposed to increase the detection rate of PA, which has the shortcoming of a high underdiagnosis rate when relying only on clinical manifestations." | 1.72 | Reliability Analysis of a Functional Diagnostic Test for Primary Hyperaldosteronism Based on Data Analysis. ( Cai, J; Wang, Y, 2022) |
"Background Primary aldosteronism (PA) is a common but under-recognized cause of secondary hypertension." | 1.72 | Primary Aldosteronism Screening Rates Differ with Sex, Race, and Comorbidities. ( Grigoryan, S; Holevinski, L; Liu, H; Nhan, W; Turcu, AF; Urban, C; Zhang, L; Zhao, L, 2022) |
"Racial differences in obstructive sleep apnea (OSA) and increased aldosterone level may explain the racial disparity in resistant hypertension prevalence." | 1.72 | Relationship Between Risks for Obstructive Sleep Apnea, Resistant Hypertension, and Aldosterone Among African American Adults in the Jackson Heart Study. ( Eaton, CB; Gjelsvik, A; Hall, ME; Koo, P; McCool, FD; Muntner, P, 2022) |
"Primary aldosteronism (PA) is the most common cause of secondary hypertension." | 1.72 | Clinical and biochemical predictors and predictive model of primary aldosteronism. ( Atthakomol, P; Manosroi, W; Tacharearnmuang, N, 2022) |
"Hypertension was induced in the rats by adding 8% NaCl in their diet for six weeks." | 1.72 | Anti-Hypertensive Effects of Anthocyanins from Hibiscus sabdarifa Calyx on the Renin-Angiotensin-Aldoslestrone System in Wistar Rats. ( Madueke, P; Nwachukwu, D; Okorie, P; Ubom, R; Ugwu, P, 2022) |
"Primary aldosteronism (PA), including aldosterone and cortisol producing adenoma (A/CPA), is the most common trigger of secondary hypertension." | 1.72 | Two cases of aldosterone and cortisol producing adenoma with different histopathological features: A case report. ( Gao, H; Li, L; Tian, H, 2022) |
"Primary aldosteronism (PA) represents the most frequent cause of endocrine arterial hypertension." | 1.72 | Prevalence of Primary Aldosteronism in Newly Diagnosed Hypertensive Patients in Primary Care. ( Asbach, E; Bekeran, M; Bidlingmaier, M; Kellnar, A; Reincke, M; Schelling, J, 2022) |
"Primary aldosteronism is the most common surgically curable cause of endocrine hypertension." | 1.72 | Impact of dedicated multidisciplinary service on patient selection and outcomes for surgical treatment of primary aldosteronism. ( Fuller, PJ; Grodski, S; Lee, JC; Libianto, R; Shen, J; Yang, J; Zhang, J, 2022) |
"Primary aldosteronism is now recognized as the most common cause of secondary hypertension." | 1.72 | Primary aldosteronism presenting as embolic myocardial infarction. ( Jin, HY; Kim, YJ; Lee, HW; Lee, KA, 2022) |
"Hypertension is a major health problem common in the elderly people." | 1.72 | Green tea could improve elderly hypertension by modulating arterial stiffness, the activity of the renin/angiotensin/aldosterone axis, and the sodium-potassium pumps in old male rats. ( Akbari, A; Gao, J; Wang, T, 2022) |
"Preeclampsia is a life-threatening disorder of pregnancy unique to humans." | 1.72 | Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia. ( Dimitriadis, E; Menkhorst, E; Santos, L; St-Pierre, Y; Young, MJ; Zhang, JG; Zhou, W, 2022) |
"Aldosterone was given for the last 4 months." | 1.72 | Effect of Metabolic Adaptation by Voluntary Running Wheel Activity and Aldosterone Inhibition on Renal Function in Female Spontaneously Hypertensive Rats. ( Atmanspacher, F; Grgic, I; Schlüter, KD; Schreckenberg, R; Wolf, A, 2022) |
"Primary aldosteronism, eponymously known as Conn's syndrome, has recently gained recognition as the most common cause of endocrine hypertension." | 1.62 | The role of surgery in Conn's syndrome - a case of refractory hypertension secondary to an aldosterone secreting adenoma. ( Bombil, I; Carides, MD; Christofides, C; Sishuba, NT, 2021) |
"Primary aldosteronism was diagnosed." | 1.62 | Hypertension with unilateral adrenal aldosterone and cortisol cosecreting adenoma: A case report. ( Chen, X; Chu, SL; Hu, Z; Luo, FX; Shao, Y; Wang, JG, 2021) |
"The Taiwan Society of Aldosteronism (TSA) Task Force reviewed the latest literature and reached a consensus after group meetings." | 1.62 | Taiwan mini-frontier of primary aldosteronism: Updating detection and diagnosis. ( Chang, CC; Chen, CK; Chen, YY; Er, LK; Lai, TS; Lu, CC; Tu, KH; Wu, VC; Zeng, YH, 2021) |
"Primary aldosteronism is an underdiagnosed cause of hypertension." | 1.62 | Intraindividual Variability of Aldosterone Concentrations in Primary Aldosteronism: Implications for Case Detection. ( Fudim, T; Hundemer, GL; Moussa, M; Sacks, B; Underhill, J; Vaidya, A; Yozamp, N, 2021) |
"Primary aldosteronism was screened by measuring plasma aldosterone concentration (PAC) and direct renin concentration (DRC) and calculating aldosterone-to-renin ratio (ARR), followed by confirmatory saline infusion test (SIT) according to Endocrine Society Guideline." | 1.62 | High prevalence and a long delay in the diagnosis of primary aldosteronism among patients with young-onset hypertension. ( Alam, S; Goyal, A; Kandasamy, D; Karthikeyan, G; Khadgawat, R; Singh, S; Vishnubhatla, S, 2021) |
" In patients who have bilateral aldosterone hypersecretion, the optimal management is a low sodium diet and lifelong treatment with a mineralocorticoid receptor antagonist administered at a dosage to maintain a high-normal serum potassium concentration without the aid of oral potassium supplements." | 1.62 | [Primary aldosteronism: from diagnosis to therapy in clinical practice]. ( Cassaniti, L; Francese, GM; Gulizia, MM; Vetri, M, 2021) |
"Objective Primary aldosteronism (PA) is a major cause of secondary hypertension." | 1.62 | Primary Aldosteronism with Parathyroid Hormone Elevation: A Single-center Retrospective Study. ( Aono, D; Fujimoto, A; Gondoh-Noda, Y; Higashitani, T; Karashima, S; Kometani, M; Matsuoka, T; Sawada, K; Takeda, Y; Usukura, M; Yoneda, T; Yoshikura, S, 2021) |
"BACKGROUND Primary aldosteronism, also known as Conn's syndrome, is a clinical condition caused by excessive production of aldosterone." | 1.62 | Hypokalemia-Induced Rhabdomyolysis Caused by Adrenal Tumor-Related Primary Aldosteronism: A Report of 2 Cases. ( Chen, CT; Lin, CM; Wang, YC, 2021) |
"Her high blood pressure was initially attributed to emotional stress, however, she was later referred for additional evaluation for secondary causes of hypertension." | 1.62 | [HYPERTENSION IN A YOUNG WOMAN WITH ANXIETY DISORDER: THE CHICKEN OR THE EGG?] ( Angel Korman, A; Hausmann, M; Katzir, Z; Rapoport, V; Raz, O, 2021) |
"Patients with primary aldosteronism (PA) have cardiac remodeling due to hemodynamic and non-hemodynamic causes." | 1.62 | Hemodynamic and Non-Hemodynamic Components of Cardiac Remodeling in Primary Aldosteronism. ( Chang, CC; Chang, YR; Chang, YY; Chen, YL; Chen, ZW; Hung, CS; Lee, BC; Liao, CW; Lin, LC; Lin, YH; Pan, CT; Tsai, CH; Wu, XM, 2021) |
"Allisartan isoproxil (ALL) is a new angiotensin II receptor blocker and a new antihypertensive drug discovered and developed in China." | 1.62 | Allisartan isoproxil reduces mortality of stroke-prone rats and protects against cerebrovascular, cardiac, and aortic damage. ( Cheng, MH; Fu, FH; Ling, QS; Liu, AJ; Liu, JG; Miao, CY; Tian, JS; Zhang, SL, 2021) |
"Primary aldosteronism (PA) is highly prevalent in hypertensive population." | 1.62 | Determination of adrenal hypersecretion in primary Aldosteronism without aldosterone-production adenomas. ( He, H; Hong, Y; Liu, X; Sun, F; Yan, Z; Zhang, H; Zhao, Z; Zhu, Z, 2021) |
"Residual hypertension was defined as persistent hypertension > 140/90 mmHg or requiring anti-hypertensive medications 1 year after surgery." | 1.62 | Comparison of cystatin C-based and creatinine-based glomerular filtration rate in the prediction of postoperative residual hypertension in aldosterone-producing adenoma patients after adrenalectomy. ( Chang, CC; Chen, CW; Chiu, YW; Hung, CS; Liao, SC; Lin, YH; Liu, KL; Tsai, CH; Tsai, IJ; Wu, VC, 2021) |
"Primary aldosteronism has two main clinically and biologically distinct subtypes: unilateral aldosterone-producing adenoma (APA) and bilateral adrenal hyperplasia (BAH)." | 1.62 | Subtype-specific trends in the clinical picture of primary aldosteronism over a 13-year period. ( Fujii, Y; Ichijo, T; Inagaki, N; Itoh, H; Kamemura, K; Katabami, T; Kawashima, J; Kobayashi, H; Kurihara, I; Naruse, M; Ogawa, Y; Oki, K; Saito, K; Sone, M; Suzuki, T; Tamura, K; Tanabe, A; Tsuiki, M; Wada, N; Yamada, M; Yamada, T; Yamamoto, K; Yasoda, A; Yoneda, T, 2021) |
"Essential hypertension is a pivotal risk factor for the development of cardiovascular disease (CVD)." | 1.62 | Aldosterone hyperreactivity to acute psychosocial stress induction in men with essential hypertension. ( Ehlert, U; Gideon, A; Sauter, C; von Känel, R; Wirtz, PH, 2021) |
"Primary aldosteronism (PA) is the most common endocrine cause of arterial hypertension." | 1.62 | Prevalence of Primary Aldosteronism Across the Stages of Hypertension Based on a New Combined Overnight Test. ( Chrousos, G; Gravvanis, C; Gryparis, A; Kaltsas, G; Kapsali, C; Kassi, E; Kyriazi, E; Markou, A; Papanastasiou, L; Piaditis, G; Tyfoxylou, E; Vlachou, S; Voulgaris, N, 2021) |
"Primary aldosteronism (PA), as a cause of secondary hypertension, can cause more serious cardiovascular damage than essential hypertension." | 1.62 | A case of primary aldosteronism with a negative aldosterone-to-renin ratio. ( Ding, Y; Liu, F; Wang, L, 2021) |
"Primary aldosteronism (PA) is a common curable cause of hypertension." | 1.56 | Historical changes and between-facility differences in adrenal venous sampling for primary aldosteronism in Japan. ( Fujii, Y; Fujita, M; Ichijo, T; Inagaki, N; Itoh, H; Kamemura, K; Katabami, T; Kawashima, J; Kobayashi, H; Kurihara, I; Matsuda, Y; Miyauchi, S; Naruse, M; Ogasawara, T; Ogawa, Y; Ogo, A; Okamura, S; Otsuki, M; Shibata, H; Shibayama, Y; Sone, M; Suzuki, T; Takahashi, K; Takeda, Y; Tsuiki, M; Umakoshi, H; Wada, N; Watanabe, M; Yamamto, K; Yanase, T; Yoshimoto, T, 2020) |
"Primary aldosteronism is a common cause of secondary hypertension." | 1.56 | Adherence to consensus guidelines for screening of primary aldosteronism in an urban healthcare system. ( Beninato, T; Fahey, TJ; Sivarajah, M, 2020) |
"Primary aldosteronism (PA) is the most frequent cause of secondary hypertension." | 1.56 | Construction of a predictive scoring system as a guide to screening and confirmation of the diagnosis of primary aldosteronism. ( Kietsiriroje, N; Murray, RD; Suntornlohanakul, O; Wonghirundecha, R, 2020) |
"Primary aldosteronism (PA) is known to increase vertebral fracture (VF), although the detailed mechanism remains to be elucidated." | 1.56 | Unilateral primary aldosteronism as an independent risk factor for vertebral fracture. ( Fukumoto, T; Matsuda, Y; Nagata, H; Ogata, M; Ogawa, Y; Sakamoto, R; Umakoshi, H; Yokomoto-Umakoshi, M, 2020) |
"Essential hypertension is a prevalence chronic cardiovascular disease, which is treated by traditional Chinese medicine (TCM) in China." | 1.56 | Pharmacodynamics and metabonomics study of Tianma Gouteng Decoction for treatment of spontaneously hypertensive rats with liver-yang hyperactivity syndrome. ( Cong, H; Dong, H; Du, W; Zhang, L; Zhang, S, 2020) |
"Primary aldosteronism (PA) contributed to the cardiovascular disease and metabolic alterations independent of the blood pressure level." | 1.56 | The effect of vitamin D treatment on clinical and biochemical outcomes of primary aldosteronism. ( Azhar Shah, S; Ismail, NA; Kamaruddin, NA; Sukor, N, 2020) |
"Hyperaldosteronism has been reported to be associated with a higher prevalence of non-alcoholic fatty liver disease (NAFLD)." | 1.56 | The risk factors for hepatic steatosis in patients with primary aldosteronism. ( Atsumi, T; Baba, S; Nakamura, A; Obara, S; Sakai, H; Shibayama, Y; Terae, S; Usubuchi, H; Wada, N, 2020) |
"Primary aldosteronism (PA) is notably an independent risk factor for cerebral vascular disease but currently with limited knowledge among young adults." | 1.56 | Primary aldosteronism in young adults with acute stroke: Prevalence and clinical characteristics. ( Chen, H; Cheng, Q; Du, Z; He, W; Hu, J; Li, Q; Luo, T; Ma, L; Mei, M; Song, Y; Tang, Z; Wang, Z; Yang, S, 2020) |
"Treatment with aliskiren decreased urinary aldosterone excretion at 4 weeks and increased it at 12 weeks." | 1.56 | Impact of mineralocorticoid receptor blockade with direct renin inhibition in angiotensin II-dependent hypertensive mice. ( Aono, D; Demura, M; Hashimoto, A; Higashitani, T; Karashima, S; Kometani, M; Konishi, S; Takeda, Y; Yoneda, T, 2020) |
"Primary aldosteronism is a nonsuppressible renin-independent aldosterone production that causes hypertension and cardiovascular disease." | 1.56 | The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study. ( Brown, JM; Calhoun, DA; Carey, RM; Hopkins, PN; Siddiqui, M; Vaidya, A; Williams, GH, 2020) |
"Hypertension was the most common chief complaint, in contrast, the proportion of fatigue and/or numbness as the symptoms of hypokalemia was declining." | 1.56 | [Diagnosis and Treatment of Primary Aldosteronism in West China Hospital of Sichuan University from 2009 to 2018]. ( Chen, T; Li, QR; Li, YM; Liu, HD; Ren, Y; Tian, HM; Wang, W; Zhu, YC, 2020) |
"Conn's syndrome is a curable condition if identified properly." | 1.56 | Seizure and coma secondary to Conn's syndrome: a case report. ( Alseddeeqi, E; Altinoz, A; Ghashir, NB, 2020) |
"Primary aldosteronism (PA) occurs in 10%-20% of patients with resistant hypertension." | 1.56 | Evaluation of Adrenal Vein Sampling Use and Outcomes in Patients With Primary Aldosteronism. ( Bloomgarden, N; Friedmann, P; In, H; Laird, AM; Libutti, SK; McAuliffe, JC; Yeung, A, 2020) |
" Catheter-based adrenal ablation appears to produce substantial and sustained blood pressure reduction and biochemical improvement, with only minor adverse events in PA patients without apparent aldosteronoma." | 1.56 | Adrenal artery ablation for primary aldosteronism without apparent aldosteronoma: An efficacy and safety, proof-of-principle trial. ( Bu, X; He, H; Hong, Y; Li, Q; Li, Y; Liu, X; Shen, R; Sun, F; Yan, Z; Yang, G; Zhang, H; Zhao, Z; Zheng, H; Zhou, X; Zhu, Z, 2020) |
"The diagnostic algorithm for primary aldosteronism is sequentially based on hormonal tests (screening and confirmation tests), followed by lateralization studies (adrenal CT scanning and adrenal venous sampling) to distinguish between unilateral and bilateral disease." | 1.56 | Genetics, prevalence, screening and confirmation of primary aldosteronism: a position statement and consensus of the Working Group on Endocrine Hypertension of The European Society of Hypertension. ( Amar, L; Beuschlein, F; Deinum, J; Fallo, F; Lin, YH; Monticone, S; Morganti, A; Mulatero, P; Nishikawa, T; Prejbisz, A; Rossi, GP; Seccia, TM; Widimsky, J; Zennaro, MC, 2020) |
" In patients with bilateral aldosterone hypersecretion, the optimal is a low-sodium diet and lifelong treatment with a mineralocorticoid receptor antagonist administered at a dosage to reach a high-normal serum potassium concentration." | 1.56 | [Primary aldosteronism: The Mayo Clinic approach]. ( Balutina, OV; Beltsevich, DG; Ladygina, DO; Young, W, 2020) |
"Hypertension is a common clinical problem, and increased aldosterone is the most prevalent underlying characteristic." | 1.56 | Body mass index predicts aldosterone production in hypertensive postmenopausal women. ( Geng, X; Hou, X; Li, L; Xu, Y, 2020) |
"Aldosterone is a key factor in adverse cardiovascular remodeling by acting on the mineralocorticoid receptor (MR) in different cell types." | 1.51 | Endothelial cell mineralocorticoid receptors oppose VEGF-induced gene expression and angiogenesis. ( Bode, C; Deng, L; Esser, JS; Fürst, D; Hein, L; Huck, M; Kowalski, J; Lother, A; Moser, M, 2019) |
"Primary aldosteronism (PA) may cause myocardial injury." | 1.51 | Speckle-Tracking Echocardiographic Layer-Specific Strain Analysis on Subclinical Left Ventricular Dysfunction in Patients With Primary Aldosteronism. ( Chen, X; Chen, Y; Li, Y; Shao, S; Wang, D; Wang, JG; Xu, JZ; Xu, TY; Zhang, W; Zhu, LM, 2019) |
"Aldosterone/renin ratio was available in 1473 patients, and abnormal in 374 (25." | 1.51 | Rates of abnormal aldosterone/renin ratio in African-origin compared to European-origin patients: A retrospective study. ( Abadi, S; Ahmed, KS; Behan, LA; Bogdanet, D; Boran, G; Dineen, R; Gibney, J; Sherlock, M; Woods, CP, 2019) |
"To determine the frequency of primary hyperaldosteronism in young hypertensives in hospital settings of Rawalpindi." | 1.51 | Frequency of Primary Hyperaldosteronism in Young Hypertensives in a Tertiary Care Setting of Rawalpindi. ( Akram, A; Asif, N; Gilani, M; Nawaz, A, 2019) |
"Primary aldosteronism (PA) is a frequent cause of resistant hypertension." | 1.51 | [Two case reports on resistant hypertension]. ( Beger, C; Haller, H; Limbourg, FP, 2019) |
"Aldosterone has been linked with obesity, metabolic syndrome (MetS), pro-inflammatory, and prothrombotic states; however, most studies relate these indicators with primary aldosteronism (PA), excluding non-PA patients." | 1.51 | The Aldosterone/Renin Ratio Predicts Cardiometabolic Disorders in Subjects Without Classic Primary Aldosteronism. ( Allende, F; Barros, ER; Baudrand, R; Campino, C; Carvajal, C; Fardella, CE; Fuentes, CA; García, H; Kalergis, AM; Martínez-Aguayo, A; Olmos, R; Solari, S; Tapia-Castillo, A; Vecchiola, A, 2019) |
"The diagnostic workup for primary aldosteronism includes a screening step using the aldosterone-to-renin ratio (ARR) and a confirmatory step based on dynamic testing of aldosterone secretion autonomy." | 1.51 | Evaluation of Biochemical Conditions Allowing Bypass of Confirmatory Testing in The Workup of Primary Aldosteronism: A Retrospective Study in a French Hypertensive Population. ( Deberles, E; Guenet, D; Haddouche, A; Morello, R; Reznik, Y; Vivien, M, 2019) |
"Patients with primary aldosteronism induced hypertension are more likely to experience cardiovascular events compared to patients with essential hypertension." | 1.51 | Hypertension with primary aldosteronism is associated with increased carotid intima-media thickness and endothelial dysfunction. ( Demirkiran, A; Dreijerink, KM; Elitok, A; Everaars, H; Ozcan, M; Smulders, YM; Tanakol, R; van de Ven, PM, 2019) |
"Primary aldosteronism (PA) is the most frequent cause of secondary hypertension." | 1.51 | Sex Difference in the Association Between Subtype Distribution and Age at Diagnosis in Patients With Primary Aldosteronism. ( Akasaka, H; Chiba, Y; Fujita, M; Ichijo, T; Izawa, S; Kamemura, K; Katabami, T; Kawashima, J; Kobayashi, H; Kurihara, I; Matsuda, Y; Miyauchi, S; Nagasawa, M; Nakamaru, R; Naruse, M; Ogawa, Y; Okamura, S; Rakugi, H; Sone, M; Takeda, Y; Tamura, K; Tanabe, A; Tsuiki, M; Wada, N; Watanabe, M; Yamamoto, K; Yoshimoto, T, 2019) |
"The diagnosis of primary hyperaldosteronism (PHPA) has progressively increased over the last years and some authors consider it as the main cause of secondary hypertension." | 1.51 | [Primary hyperaldosteronism in a population of hypertensive patients]. ( Artiles Vizcaíno, J; Lorenzo Villalba, N; Marrero Medina, I; Rivera Martínez, E; Sablón González, N; Suárez Ortega, S, 2019) |
"Primary aldosteronism (PA) is hemodynamically independently associated with arterial wall stiffness as assessed by pulse wave velocity (PWV) compared with essential hypertension." | 1.51 | Aldosterone Induces Vascular Damage. ( Chang, CC; Chen, CH; Chen, ZW; Cheng, HM; Hung, CS; Liao, CW; Lin, YH; Pan, CT; Sung, SH; Wu, VC, 2019) |
"The diagnostic criteria of primary aldosteronism were plasma aldosterone concentration-to-plasma renin activity ratio [ARR, (ng/dl)/(ng/ml per h)] at least 20 and at least one positive result in four types of challenge tests." | 1.48 | Screening of primary aldosteronism by clinical features and daily laboratory tests: combination of urine pH, sex, and serum K. ( Ando, T; Endo, T; Fukuhara, S; Fukuma, S; Hasegawa, T; Koyama, M; Mita, T; Miura, T; Moniwa, N; Ohno, K; Ohnuma, Y; Shimizu, S; Takada, A; Tobisawa, T; Togashi, N; Tsuchida, A; Yamashita, T; Yoshida, H, 2018) |
"The aldosterone-treated mice were exposed to NaCl drinking water (1%) during the hormone administration." | 1.48 | Disruption of the with no lysine kinase-STE20-proline alanine-rich kinase pathway reduces the hypertension induced by angiotensin II. ( Alessi, DR; Bobadilla, NA; Castaneda-Bueno, M; Cervantes-Perez, LG; Gamba, G; Jimenez, JV; Rojas-Vega, L; Vazquez, N, 2018) |
"Primary aldosteronism is associated with a higher incidence of left ventricular (LV) hypertrophy and diastolic dysfunction than essential hypertension." | 1.48 | Aldosterone induces left ventricular subclinical systolic dysfunction: a strain imaging study. ( Chang, YY; Chen, CW; Chen, ZW; Huang, KC; Hung, CS; Lee, JK; Liao, CW; Lin, LC; Lin, YH; Wu, VC, 2018) |
"In patients with KCNJ5-mutated APA, left ventricular hypertrophy was significantly decreased by surgical treatment in patients from either Cured or Improved groups, although those patients with wild-type KCNJ5 showed no change." | 1.48 | KCNJ5 mutation as a predictor for resolution of hypertension after surgical treatment of aldosterone-producing adenoma. ( Kitamoto, T; Nishikawa, T; Omura, M; Saito, J; Suematsu, S, 2018) |
"The Primary Aldosteronism Surgical Outcomes (PASO) group recently established new consensus definitions for biochemical and clinical cure of PA." | 1.48 | Refining the Definitions of Biochemical and Clinical Cure for Primary Aldosteronism Using the Primary Aldosteronism Surgical Outcome (PASO) Classification System. ( Auchus, RJ; Cohen, MS; Gauger, PG; Hughes, DT; Miller, BS; Nanba, AT; Turcu, AF, 2018) |
"Microalbuminuria was determined from 24-hour urine collections." | 1.48 | Aldosterone as a mediator of microvascular and macrovascular damage in a population of normotensive to early-stage hypertensive individuals. ( Anyfanti, P; Douma, S; Gavriilaki, E; Gkaliagkousi, E; Lazaridis, A; Nikolaidou, B; Triantafyllou, A; Vamvakis, A, 2018) |
"Primary aldosteronism (PA) is the most frequent cause of secondary hypertension." | 1.48 | Prevalence of primary aldosteronism in primary care: a cross-sectional study. ( Biermans, MC; Bor, HJ; de Grauw, WJ; Deinum, J; Käyser, SC; Lenders, JW; Schalk, BW; Schermer, TR, 2018) |
"Primary aldosteronism (PA) is the most common endocrine form of arterial hypertension." | 1.48 | Primary aldosteronism: key characteristics at diagnosis: a trend toward milder forms. ( Adolf, C; Beuschlein, F; Hahner, S; Heinrich, DA; Januszewicz, A; Nirschl, N; Quack, I; Quinkler, M; Reincke, M; Rump, LC; Seufert, J; Sturm, L; Willenberg, HS, 2018) |
"Primary aldosteronism (PA) is a common form of secondary hypertension." | 1.48 | Primary aldosteronism in patients with adrenal incidentaloma: Is screening appropriate for everyone? ( Athyros, VG; Doumas, M; Finitsis, S; Georgopoulou, V; Imprialos, KP; Kamparoudis, A; Karagiannis, A; Katsiki, N; Papadopoulos, C; Petidis, K; Petras, P; Stavropoulos, K, 2018) |
"Venous thrombosis was induced by vena cava ligation." | 1.48 | Beneficial effect of combined spironolactone and quinapril treatment on thrombosis and hemostasis in 2K1C hypertensive rats. ( Aleksiejczuk, M; Chabielska, E; Gromotowicz-Poplawska, A; Marcinczyk, N; Mikita, J; Stankiewicz, A; Szemraj, J, 2018) |
"Primary hyperaldosteronism as compared to other renin angiotensin aldosterone system disorders was found to be the leading cause of hypertension in young population." | 1.48 | Spectrum of renin angiotensin aldosterone system disorders in young hypertensives. ( Akram, A; Asif, N; Gilani, M; Ijaz, A; Malik, SS, 2018) |
"Current threshold values for primary aldosteronism (PA) diagnostic testing are based on measuring aldosterone (PAC) using immunoassays." | 1.48 | Aldosterone LC-MS/MS Assay-Specific Threshold Values in Screening and Confirmatory Testing for Primary Aldosteronism. ( Ahmed, AH; Gordon, RD; Guo, Z; McWhinney, BC; Poglitsch, M; Stowasser, M; Ungerer, JPJ; Wolley, M, 2018) |
"Primary aldosteronism affects ≈5% to 10% of hypertensive patients and has unilateral and bilateral forms." | 1.48 | Cellular and Genetic Causes of Idiopathic Hyperaldosteronism. ( Anand, SK; Guo, Z; Ito, S; Morimoto, R; Nakamura, Y; Omata, K; Rainey, WE; Sasano, H; Satoh, F; Stowasser, M; Tomlins, SA; Yamazaki, Y, 2018) |
"Primary aldosteronism is a secondary hypertensive disease caused by autonomous aldosterone production that often caused by an aldosterone-producing adenoma (APA)." | 1.48 | Aldosterone and 18-Oxocortisol Coaccumulation in Aldosterone-Producing Lesions. ( Higashi, T; Kosaka, T; Mizuno, Y; Nishikawa, T; Nishimoto, K; Omura, M; Oya, M; Seki, T; Shimma, S; Suematsu, M; Sugiura, Y; Takeo, E; Yokota, M, 2018) |
"Family hyperaldosteronism type I (glucocorticoids-remediable hyperaldosteronism) is a rare form of symptomatic arterial hypertension (AH), which often leads to the development of cerebrovascular complications." | 1.48 | Family hyperaldosteronism type I: a clinical case and review of literature. ( Chazova, IE; Chikladze, NM; Favorova, OO, 2018) |
"Exploration showed primary hyperaldosteronism (aldosterone = 2645 pmol/l, aldosterone/renin ratio = 327 pmol/MUI), with hypersecretion of glucocorticoids." | 1.48 | [Corticosurrenaloma: an exceptional cause of primary hyperaldosteronism]. ( Alaya, W; Ammari, FL; Arfa, S; Berriche, O; Boubaker, F; Charrada, I; Elati, Z; Sfar, MH; Zantour, B, 2018) |
"Aldosterone is a major mineralocorticoid hormone that plays a key role in the regulation of blood pressure and is implicated in the pathogenesis of hypertension and heart failure." | 1.46 | Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice. ( Du, N; Du, Y; Gu, H; Kowala, MC; Ma, Z; Shatara, A; Wang, J; Yi, X; Zhu, T, 2017) |
"Primary aldosteronism is characterized by excess aldosterone (ALDO) secretion independent of the renin-angiotensin system and accounts for approximately 10% of hypertension cases." | 1.46 | Role and Regulation of MicroRNAs in Aldosterone-Mediated Cardiac Injury and Dysfunction in Male Rats. ( Ball, JP; Hall, ME; Kc, R; Marañon, RO; Reckelhoff, JF; Romero, DG; Syed, M; Yanes Cardozo, LL, 2017) |
"Primary aldosteronism is a common cause of hypertension, which becomes refractory if undiagnosed, but potentially curable when caused by an aldosterone-producing adenoma (APA)." | 1.46 | Physiological and Pathological Roles in Human Adrenal of the Glomeruli-Defining Matrix Protein NPNT (Nephronectin). ( Brown, MJ; Garg, S; Gomez-Sanchez, CE; Gurnell, M; Johnson, TI; Teo, AE; Zhao, W; Zhou, J, 2017) |
"Aldosterone is a uniquely terrestrial hormone, first appearing in lungfish, which have both gills and lungs." | 1.46 | Aldosterone and Mineralocorticoid Receptors-Physiology and Pathophysiology. ( Funder, JW, 2017) |
"Primary hyperaldosteronism is a common cause of hypertension in the adult population." | 1.46 | A case of confirmed primary hyperaldosteronism diagnosed despite normal screening investigations. ( Carroll, R; Feltham, J; Gould, A; Harper, S, 2017) |
"Vitamin D deficiency is associated with hypertension." | 1.46 | Nocturnal diastolic blood pressure decline is associated with higher 25-hydroxyvitamin D level and standing plasma renin activity in a hypertensive population. ( Gao, M; Li, H; Liu, H; Xu, X; Zhang, J; Zhang, M, 2017) |
"Consecutive patients with diagnosed primary hyperaldosteronism from June 2006 to July 2012 in our center underwent adrenal surgeries without pre-operational adrenal venous sampling (AVS) if all the three criteria were met: (1) round- or oval-shaped occupational lesion of low density after contrast enhancement with diameter >1 cm on CT scan was located in one adrenal gland; (2) unequivocally normal contralateral adrenal gland; (3) serum potassium level lower than 3." | 1.46 | Favorable surgical outcomes of aldosterone-producing adenoma based on lateralization by CT imaging and hypokalemia: a non-AVS-based strategy. ( Cao, X; Feng, X; Li, H; Li, Y; Liu, J; Liu, L; Wei, G, 2017) |
"Primary aldosteronism is recognized as a severe form of renin-independent aldosteronism that results in excessive mineralocorticoid receptor (MR) activation." | 1.46 | The Spectrum of Subclinical Primary Aldosteronism and Incident Hypertension: A Cohort Study. ( Allison, MA; Baudrand, R; Brown, JM; de Boer, IH; Ix, JH; Kestenbaum, B; Luque-Fernandez, MA; Robinson-Cohen, C; Vaidya, A, 2017) |
"Primary hyperaldosteronism is an adrenal abnormality in which there is some degree of autonomy of aldosterone secretion." | 1.46 | Primary Hyperaldosteronism Due to Adrenocortical Adenoma: a Case Report. ( Amarwati, S; Naibaho, R; Pemayun, TGD; Santosa, A; Wiyati, MW, 2017) |
"A total of 62 primary aldosteronism and 56 essential hypertension patients were enrolled." | 1.46 | Increased urinary excretion of the epithelial Na channel activator prostasin in patients with primary aldosteronism. ( Castagna, A; Chiariello, C; Chiecchi, L; Morandini, F; Olivieri, O; Pattini, P; Pizzolo, F; Salvagno, G; Zaltron, C; Zorzi, F, 2017) |
"Liddle syndrome is a rare autosomal dominant monogenic form of hypertension." | 1.46 | Liddle syndrome: clinical and genetic profiles. ( Cui, Y; Jiang, J; Li, C; Tong, A; Wang, F, 2017) |
"We described the prevalence of primary aldosteronism in our population before the change and, using the assumption of disease prevalence stability, determined the corresponding ratio cutoffs after the introduction of the new assay." | 1.46 | Novel Approach to Establishing an Aldosterone: Renin Ratio Cutoff for Primary Aldosteronism. ( Chin, A; Kline, GA; Leung, AA; Orton, DJ; Sadrzadeh, H, 2017) |
"All primary aldosteronism patients were diagnosed by autonomous aldosterone secretion using confirmatory tests, and then divided into nPA (n = 130) and primary aldosteronism patients with high PAC (hPA: n = 162) using a PAC cutoff level of less than 443 pmol/l (16 ng/dl), representing the normal upper limit of PAC." | 1.46 | Plasma aldosterone level within the normal range is less associated with cardiovascular and cerebrovascular risk in primary aldosteronism. ( Hamasaki, T; Hashimoto, K; Hayashi, RD; Kajimoto, Y; Kitamura, T; Kouhara, H; Kurebayashi, S; Mukai, K; Murata, M; Nakao, M; Otsuki, M; Shimomura, I; Takeiri, S; Tamada, D; Yamamoto, T, 2017) |
"Finally, the Liddle syndrome was diagnosed because of the DNA sequencing found that the proband's mother and himself had mutations P616L (c." | 1.46 | The importance of genetic counseling and genetic screening: a case report of a 16-year-old boy with resistant hypertension and severe hypokalemia. ( Jiang, L; Kuang, ZM; Liu, JH; Wang, JJ; Wang, Y; Yu, ZQ; Zeng, R; Zhou, Q, 2017) |
"Primary hyperaldosteronism (PHA) is one of the most common endocrine forms of secondary hypertension." | 1.43 | Sodium interference in the determination of urinary aldosterone. ( Aldea, ML; Barallat, J; Granada, ML; Martín, MA; Pastor, MC; Rosas, I, 2016) |
"HFpEF mice developed hypertension, left ventricular hypertrophy, and diastolic dysfunction and had higher myocardial natriuretic peptide expression." | 1.43 | Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue. ( Aprahamian, T; Fuster, JJ; Hulsmans, M; Li, S; Nahrendorf, M; Sam, F; Scherer, PE; Valero-Muñoz, M; Wilson, RM, 2016) |
"Eplerenone treatment of patients with PA reduces blood pressure, increases serum potassium level, and improves vascular status." | 1.43 | Eplerenone improves carotid intima-media thickness (IMT) in patients with primary aldosteronism. ( Anzai, K; Kawate, H; Matsuda, Y; Matsuzaki, C; Nomura, M; Ohnaka, K; Sakamoto, R; Shibue, K; Takayanagi, R, 2016) |
"Aldosterone excess can cause DNA damage in vitro and in vivo." | 1.43 | Prevalence of Malignancies in Patients With Primary Aldosteronism. ( Allolio, B; Dietz, AS; Friedrichs, N; Fuss, CT; Hahner, S; Hannemann, A; Heinze, B; Lang, K; Quack, I; Quinkler, M; Reincke, M; Rump, LC; Wallaschofski, H; Weber, K; Willenberg, HS, 2016) |
" The aim of this study was to investigate whether or not the effect of β-blocker therapy on the ARR could be predicted from the dosing regimen." | 1.43 | A cross-sectional study of the effects of β-blocker therapy on the interpretation of the aldosterone/renin ratio: can dosing regimen predict effect? ( Browne, GA; Dennedy, MC; Griffin, TP; OʼShea, PM; Wall, D, 2016) |
"To investigate the clinical features of adrenocortical adenoma's diagnosis and treatment in patients aged 60 years or above." | 1.43 | [Clinical diagnosis and treatment of adrenocortical adenoma in patients aged 60 years or above]. ( Huang, Z; Ji, Z; Li, J, 2016) |
"Primary aldosteronism is one of the most common forms of secondary hypertension, but it is often under diagnosed, which leads to the development of cardiovascular damage, and excess costs for long-term drug treatment and management of complications." | 1.43 | The Aldosterone Renin Ratio (ARR) APP as Tool to Enhance the Detection Rate of Primary Aldosteronism. ( Bisogni, V; Rossi, GP, 2016) |
"Aldosterone/renin ratio was calculated as aldosterone concentration/renin activity." | 1.43 | Association of Circulating Renin and Aldosterone With Osteocalcin and Bone Mineral Density in African Ancestry Families. ( Bunker, CH; Kammerer, CM; Kuipers, AL; Patrick, AL; Pratt, JH; Wheeler, VW; Zmuda, JM, 2016) |
"To establish the cause of primary aldosteronism (PA), it is essential to distinguish unilateral from bilateral adrenal aldosterone secretion, as adrenalectomy improves aldosterone secretion and controls hypertension and hypokalemia only in the former." | 1.43 | SFE/SFHTA/AFCE consensus on primary aldosteronism, part 4: Subtype diagnosis. ( Bardet, S; Chamontin, B; Douillard, C; Hernigou, A; Joffre, F; Pagny, JY; Plouin, PF; Steichen, O, 2016) |
"Aldosterone effects were prevented by the AGTR1 antagonist losartan in WT mice." | 1.43 | Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors. ( Barhoumi, T; Briet, M; Coelho, SC; Coffman, TM; Mian, MOR; Ouerd, S; Paradis, P; Rautureau, Y; Schiffrin, EL, 2016) |
"Primary aldosteronism (PA) is the most common cause of endocrine hypertension that is diagnosed following a two-step process: an initial screening test, based on the serum aldosterone-to-renin ratio (ARR), followed by a relatively laborious and time-consuming confirmatory test to document autonomous aldosterone (ALD) secretion." | 1.43 | A new highly sensitive and specific overnight combined screening and diagnostic test for primary aldosteronism. ( Androulakis, II; Chrousos, GP; Kaltsas, G; Kassi, E; Kounadi, T; Markou, A; Papanastasiou, L; Piaditis, GP; Tsiavos, V; Voulgaris, N; Zachaki, A, 2016) |
"Primary aldosteronism (PA) is one of the most frequent forms of secondary hypertension, associated with atherosclerosis and higher risk of cardiovascular events." | 1.43 | Enhanced Soluble Serum CD40L and Serum P-Selectin Levels in Primary Aldosteronism. ( Carnevale, R; Ciardi, A; Concistrè, A; De Toma, G; Galassi, M; Iacobellis, G; Iannucci, G; Letizia, C; Lucia, P; Marinelli, C; Petramala, L; Pignatelli, P; Violi, F; Zinnamosca, L, 2016) |
"Our data indicate that in mice with Liddle syndrome, the primary site of increased Na(+) reabsorption is the DCT2/CNT." | 1.43 | In Liddle Syndrome, Epithelial Sodium Channel Is Hyperactive Mainly in the Early Part of the Aldosterone-Sensitive Distal Nephron. ( Bertog, M; Dahlmann, A; Korbmacher, C; Krueger, B; Nesterov, V; Palmisano, R, 2016) |
"In patients with suspected primary aldosteronism (PA), the first diagnostic step, screening, must have high sensitivity and negative predictive value." | 1.43 | SFE/SFHTA/AFCE Consensus on Primary Aldosteronism, part 2: First diagnostic steps. ( Douillard, C; Girerd, X; Houillier, P; Nussberger, J, 2016) |
"Aldosterone/renin ratio was elevated in 99 patients of whom 31 exhibited elevated supine aldosterone, as well." | 1.43 | [Renin and aldosterone determinations in hypertensive patients]. ( Bajnok, L; Bódis, B; Hussein, T; Mezősi, E; Nemes, O; Rucz, K, 2016) |
"In older patients, primary aldosteronism, obstructive sleep apnoea and renal artery stenosis are more prevalent than previously thought." | 1.43 | Secondary hypertension in adults. ( Debajyoti, R; How, CH; Khoo, J; Mok, Y; Ng, AK; Puar, TH, 2016) |
"To investigate the diagnostic value of plasma aldosterone-to-active-renin ratio(ARR)in combination with plasma aldosterone concentration(PAC)in the predication of aldosteronoma(APA)." | 1.43 | [An evaluation of plasma aldosterone-to-active-renin ratio in different postures in combination with aldosterone concentration in the diagnosis of aldosteronoma]. ( Ba, JM; Dou, JT; Gu, WJ; Guo, QH; Jin, N; Lyu, ZH; Mu, YM; Wang, XL; Yang, GQ; Yang, LJ; Zang, L; Zhu, J, 2016) |
"Hypertension was resolved less frequently after treatment with RFA compared with laparoscopic adrenalectomy (13 of 36 versus 19 of 27 patients; P = 0·007)." | 1.43 | Radiofrequency ablation compared with laparoscopic adrenalectomy for aldosterone-producing adenoma. ( Chiu, PW; Chow, FC; Chu, CM; Kong, AP; Liu, SY; Ng, EK; Wong, SK, 2016) |
"Prospective studies indicate that hyperaldosteronism is found in 20% of patients with resistant hypertension." | 1.43 | Body Mass Index Predicts 24-Hour Urinary Aldosterone Levels in Patients With Resistant Hypertension. ( Calhoun, DA; Dudenbostel, T; Ghazi, L; Li, P; Liu, M; Oparil, S, 2016) |
"Primary aldosteronism (PA), the most common form of secondary hypertension, causes relevant morbidity." | 1.43 | The Clinical Value of Salivary Aldosterone in Diagnosis and Follow-Up of Primary Aldosteronism. ( Asbach, E; Bidlingmaier, M; Fourkiotis, V; Gerum, S; Lichtenauer, UD; Manolopoulou, J; Quinkler, M; Reincke, M, 2016) |
"Hypertension is the prime risk factor for stroke, and primary aldosteronism (PA) is the most common cause of secondary hypertension." | 1.43 | Primary aldosteronism in patients with acute stroke: prevalence and diagnosis during initial hospitalization. ( Joki, H; Kamide, T; Kawabata, Y; Kitamura, Y; Minami, T; Miyaji, Y; Mori, K; Nakaguchi, H; Nomura, M; Sasaki, M; Seki, S; Shima, H; Tamase, A; Tanaka, F; Tsunoda, T; Yamada, M, 2016) |
"To determine the prevalence of primary aldosteronism (PA) in hypertensive patients presenting to the primary care clinic at The Mount Sinai Hospital, regardless of the degree of hypertension and to identify clinical criteria that should prompt screening for PA." | 1.43 | PREVELENCE OF PRIMARY ALDOSTERONISM IN AN URBAN HYPERTENSIVE POPULATION. ( Amer, C; Bagiella, E; Boyajian, MK; Cheesman, KC; Galati, SJ; Hopkins, SM; Inabnet, WB; Krakoff, L; Levine, AC; Springer-Miller, R; Ying, TK; Zhuk, RA, 2016) |
"Obesity-related hypertension is associated with increased activity of the renin-angiotensin-aldosterone system (RAAS), increasing arterial stiffness." | 1.42 | Reduction of plasma aldosterone and arterial stiffness in obese pre- and stage1 hypertensive subjects after aerobic exercise. ( Chaudhuri, D; Collier, SR; Curry, CD; Frechette, V; Gowdar, R; Ji, H; Meucci, M; Moody, AM; Sandberg, K, 2015) |
"The diagnosis of primary aldosteronism (PA) among the older-aged population has posed a crucial challenge." | 1.42 | The value of losartan suppression test in the confirmatory diagnosis of primary aldosteronism in patients over 50 years old. ( Balakrishnan, P; Chen, YM; Chueh, SC; Hsein, YC; Kuo, CC; Wang, MJ; Wu, KD; Wu, VC, 2015) |
"Primary aldosteronism could exert a negative feedback on prorenin secretion, of possibly different magnitude, whether it is related to an aldosterone-producing adenoma (APA) or an idiopathic hyperaldosteronism (IHA)." | 1.42 | Decreased plasma prorenin levels in primary aldosteronism: potential diagnostic implications. ( Berge, C; Bricca, G; Courand, PY; Fauvel, JP; Harbaoui, B; Khettab, F; Lantelme, P; Paget, V, 2015) |
"Hypertension was improved in 97% and normalized in 38%." | 1.42 | Primary aldosteronism: functional histopathology and long-term follow-up after unilateral adrenalectomy. ( Calissendorff, J; Hamberger, B; Höög, A; Mukai, K; Thorén, M; Volpe, C; Wahrenberg, H; Zedenius, J, 2015) |
"Aldosterone levels were compared to those in age-matched males undergoing FST." | 1.42 | Should aldosterone suppression tests be conducted during a particular phase of the menstrual cycle, and, if so, which phase? Results of a preliminary study. ( Ahmed, AH; Gordon, RD; Kogovsek, C; Stowasser, M; Ward, G; Wolley, M, 2015) |
"If detected in patients with primary aldosteronism could implicate prorenin in the development of primary aldosteronism." | 1.42 | Expression and functional role of the prorenin receptor in the human adrenocortical zona glomerulosa and in primary aldosteronism. ( Belloni, AS; Caroccia, B; Ceolotto, G; Gonzales-Campos, A; Lenzini, L; Nussberger, J; Petrelli, L; Rainey, WE; Recarti, C; Rossi, GP; Seccia, TM, 2015) |
"Primary aldosteronism is the most frequent endocrine cause of secondary hypertension." | 1.42 | Primary aldosteronism and its various clinical scenarios. ( Abad-Cardiel, M; Alvarez-Alvarez, B; García-Donaire, JA; Martell-Claros, N; Pérez, CF, 2015) |
"Aldosterone has hypertrophic and profibrotic effects on the heart." | 1.42 | Plasma aldosterone and left ventricular diastolic function in treatment-naïve patients with hypertension: tissue-Doppler imaging study. ( Catena, C; Kraigher-Krainer, E; Pieske, B; Pilz, S; Sechi, LA; Tomaschitz, A; Verheyen, N, 2015) |
"Resistant hypertension is common, mainly idiopathic, but sometimes related to primary aldosteronism." | 1.42 | Reliability of a Bayesian network to predict an elevated aldosterone-to-renin ratio. ( Baguet, JP; Ducher, M; Fauvel, JP; Lantelme, P; Mounier-Véhier, C; Vaisse, B, 2015) |
"Primary aldosteronism (PA) is present in up to 20% of patients with treatment-resistant hypertension (TRH)." | 1.42 | Cost-Effectiveness of Therapeutic Drug Monitoring in Diagnosing Primary Aldosteronism in Patients With Resistant Hypertension. ( Arbique, D; Brinker, S; Chung, O; Das, SR; Lotan, Y; Pandey, A; Price, A; Raza, F; Velasco, A; Vongpatanasin, W, 2015) |
"This agent could be useful for the treatment of hypertension, cardiovascular and renal disorders." | 1.42 | Pharmacological profile of CS-3150, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist. ( Aoki, K; Arai, K; Homma, T; Ishikawa, H; Mizuno, M; Morikawa, Y; Sada, T; Tsuruoka, H; Ubukata, N, 2015) |
"Little is known about the prevalence of Liddle syndrome." | 1.42 | Prevalence of Liddle Syndrome Among Young Hypertension Patients of Undetermined Cause in a Chinese Population. ( Bian, J; Hui, RT; Jiang, XJ; Liu, YX; Song, L; Wang, LP; Wu, HY; Yang, KQ; Zhang, HM; Zhou, XL; Zou, YB, 2015) |
"Although primary aldosteronism is associated with more prominent cardiac remodeling and diastolic dysfunction, the reversibility of diastolic function is unclear." | 1.42 | Circulating tissue inhibitor of matrix metalloproteinase-1 is associated with aldosterone-induced diastolic dysfunction. ( Chang, YS; Chang, YY; Chen, MF; Chen, YH; Chou, CH; Ho, YL; Hung, CS; Lin, YH; Su, MJ; Tsai, YC; Wu, KD; Wu, VC; Wu, XM, 2015) |
"Primary aldosteronism (PA) is characterized by the autonomous overproduction of aldosterone." | 1.42 | Screening for primary aldosteronism in an argentinian population: a multicenter prospective study. ( Belli, SH; Chervin, RA; Contreras, LN; Cornaló, D; Costa, L; Damilano, SA; Fenili, CA; Gómez, RM; Leal Reyna, M; Lupi, SN; Martínez, MS; Nofal, MT; Pardes, EM; Rossi, MA; Ruibal, GF, 2015) |
"Primary aldosteronism affects 6% of hypertensive patients." | 1.42 | [Primary aldosteronism]. ( Amar, L, 2015) |
"Aldosterone suppression was assessed in 73 essential hypertensive and 46 primary aldosteronism patients." | 1.42 | Clinical validation for the aldosterone-to-renin ratio and aldosterone suppression testing using simultaneous fully automated chemiluminescence immunoassays. ( Bidlingmaier, M; Diederich, S; Dietz, A; Fischer, E; Grimminger, P; Holmes, D; Junnila, R; Manolopoulou, J; Morganti, A; Reincke, M, 2015) |
"Here we describe three women with hyperaldosteronism, two who presented in pregnancy and one who presented after menopause." | 1.42 | Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations. ( Azizan, EA; Bienz, M; Brown, MJ; Garg, S; Gurnell, M; Happerfield, L; Karet Frankl, FE; Marker, A; Shaikh, LH; Teo, AE; Zhou, J, 2015) |
"Aldosterone predicts new HTN, central obesity, T2DM, and use of lipid-lowering drugs in the general community and remains associated with HTN, obesity, and CKD over 4 years." | 1.42 | Aldosterone Predicts Cardiovascular, Renal, and Metabolic Disease in the General Community: A 4-Year Follow-Up. ( Bailey, KR; Buglioni, A; Burnett, JC; Cannone, V; Heublein, DM; Rodeheffer, RJ; Sangaralingham, SJ; Sarzani, R; Scott, CG, 2015) |
"Primary aldosteronism (PA) is the most frequent form of secondary hypertension, but diagnostic tools for this disease still lack optimal accuracy." | 1.40 | NT-proBNP, a useful tool in hypertensive patients undergoing a diagnostic evaluation for primary aldosteronism. ( Aprili, I; Castagna, A; Chiecchi, L; Consoli, L; Guarini, P; Olivieri, O; Pavan, C; Pizzolo, F; Salvagno, GL; Zorzi, F, 2014) |
"Prehypertension has been associated with adverse cerebrovascular events and brain damage." | 1.40 | Long-term prehypertension treatment with losartan effectively prevents brain damage and stroke in stroke-prone spontaneously hypertensive rats. ( He, DH; Lin, JX; Lin, LM; Ning, RB; Wang, HJ; Xu, CS; Zhang, LM, 2014) |
"Hypertension is accompanied by high or low circulating AngII levels and cardiac/renal injury." | 1.40 | Autocrine and paracrine function of Angiotensin 1-7 in tissue repair during hypertension. ( Chen, Y; Liu, C; Liu, H; Meng, W; Sun, Y; Zhao, T; Zhao, W, 2014) |
"Hypertension and depression are frequent comorbidities of diabetes." | 1.40 | Renin-angiotensin-aldosterone-blockade is associated with decreased use of antidepressant therapy in patients with type 1 diabetes and diabetic nephropathy. ( Ahola, AJ; Forsblom, C; Groop, PH; Harjutsalo, V, 2014) |
"Aldosterone was associated with higher SBP only in Hispanics (2." | 1.40 | Association of renin and aldosterone with ethnicity and blood pressure: the Multi-Ethnic Study of Atherosclerosis. ( Allison, MA; Budoff, M; Ix, JH; Jenny, NS; Khaki, AR; McClelland, RL; Rifkin, DE; Watson, K, 2014) |
"In 10 patients with primary aldosteronism, median supine ARRP was 298 (range 48-1222) and ARRD 34 (range 2." | 1.40 | Measurement of plasma renin concentration instead of plasma renin activity decreases the positive aldosterone-to-renin ratio tests in treated patients with essential hypertension. ( Bassani, N; Biganzoli, E; Gritti, A; Lonati, C; Morganti, A, 2014) |
"Hypertension was cured in 24 cases (38 %), and 28 patients (45 %) showed improvement with a reduction in AM." | 1.40 | Is adrenal venous sampling mandatory before surgical decision in case of primary hyperaldosteronism? ( Baguet, JP; Chabre, O; Chaffanjon, P; Naem, N; Pirvu, A; Thony, F, 2014) |
"A correct diagnosis of primary aldosteronism (PA) requires adrenal venous sampling (AVS) for the classification of subtypes (bilateral hyperplasia, BAH, or adenoma, APA)." | 1.40 | Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma. ( Brazzarola, P; Castagna, A; Cecconi, D; Chiecchi, L; D'Alessandro, A; Guarini, P; Gunasekaran, M; Morandini, F; Mulatero, P; Olivieri, O; Pizzolo, F; Veglio, F; Zolla, L, 2014) |
"Canrenone is a derivative of spironolactone with lower antiandrogen activity." | 1.40 | Aldosterone receptor blockers spironolactone and canrenone: two multivalent drugs. ( Armanini, D; Bordin, L; Clari, G; Donà, G; Sabbadin, C, 2014) |
"Adrenal hyperplasia was apparent on post-mortem histopathology." | 1.40 | Hypokalaemia in a hyperthyroid domestic shorthair cat with adrenal hyperplasia. ( Elwood, C; Fryers, A, 2014) |
"Primary aldosteronism (PA), the most frequent form of secondary hypertension, is characterized by a higher rate of cardiovascular (CV) events than essential hypertension (EH)." | 1.40 | Primary aldosteronism and essential hypertension: assessment of cardiovascular risk at diagnosis and after treatment. ( Boscaro, M; Ceccoli, L; di Tizio, V; Giacchetti, G; Ronconi, V; Turchi, F, 2014) |
"When hexamethonium was used to assess autonomic control of MAP, no differences in the decrease of MAP in response to ganglionic blockade were detected during the induction." | 1.40 | CNS neuroplasticity and salt-sensitive hypertension induced by prior treatment with subpressor doses of ANG II or aldosterone. ( Beltz, T; Clayton, SC; Johnson, AK; Xue, B; Zhang, Z, 2014) |
"Aldosterone-salt treatment induces not only hypertension but also extensive inflammation that contributes to fibrosis in the rat kidney." | 1.40 | Mizoribine ameliorates renal injury and hypertension along with the attenuation of renal caspase-1 expression in aldosterone-salt-treated rats. ( Doi, S; Doi, T; Kohno, N; Masaki, T; Nakashima, A; Ueno, T; Yokoyama, Y, 2014) |
"From 257 consecutive primary aldosteronism patients, we identified 176 who had both a diagnosis of APA by the 'four corners' criteria and high-quality echocardiographic data." | 1.40 | KCNJ5 gene somatic mutations affect cardiac remodelling but do not preclude cure of high blood pressure and regression of left ventricular hypertrophy in primary aldosteronism. ( Cesari, M; Cicala, MV; Iacobone, M; Kuppusamy, M; Letizia, C; Mantero, F; Mareso, S; Pessina, AC; Rossi, GP; Sciomer, S; Seccia, TM; Zinnamosca, L, 2014) |
"The prevalence of primary aldosteronism (PA) in hypertensive patients varies according to diagnostic testing and ascertained normal cut-offs." | 1.40 | Primary aldosteronism in hypertensive patients: clinical implications and target therapy. ( Chrousos, G; Dasou, A; Fountoulakis, S; Gouli, A; Gryparis, A; Kaltsas, G; Kounadi, T; Markou, A; Papanastasiou, L; Pappa, T; Piaditis, G; Samara, C; Tsiama, V; Tsounas, P; Zografos, G, 2014) |
"Primary aldosteronism, an important form of secondary hypertension, is associated with significant increase of cardiovascular risk (ischaemic heart, cerebrovascular events, arrhythmias) (relative risk 4." | 1.40 | Oxidative stress in patients affected by primary aldosteronism. ( Carnevale, R; Concistrè, A; De Toma, G; Letizia, C; Marinelli, C; Petramala, L; Pignatelli, P; Settevendemmie, A; Tonnarini, G; Violi, F; Zinnamosca, L, 2014) |
"Primary aldosteronism (PA) is common in young or middle-aged hypertensive patients, but PA among the elderly has recently become more common." | 1.40 | The influence of aging on the diagnosis of primary aldosteronism. ( Hongyo, K; Ito, N; Kamide, K; Kawai, T; Nakama, C; Onishi, M; Rakugi, H; Sugimoto, K; Takeya, Y; Yamamoto, K, 2014) |
"In 33 hypertensive patients with type 2 diabetes mellitus treated with a calcium channel blocker other than cilnidipine, we evaluated the influence of switching to cilnidipine on blood pressure, heart rate, catecholamine, plasma renin and aldosterone concentration, brain natriuretic peptide, urine liver-type fatty acid binding protein, and urinary albumin excretion ratio in the same patients by a cross-over design." | 1.40 | Effects of cilnidipine on sympathetic nerve activity and cardiorenal function in hypertensive patients with type 2 diabetes mellitus: association with BNP and aldosterone levels. ( Ichihara, A; Itoh, H; Nishimura, T; Sekioka, R; Tanaka, M, 2014) |
"In primary aldosteronism (PA), lateralized aldosterone excess can be treated with aldosterone antagonists or surgery, which raises the question as to whether surgery or medications should be the preferred management." | 1.39 | Medical or surgical therapy for primary aldosteronism: post-treatment follow-up as a surrogate measure of comparative outcomes. ( Dias, VC; Harvey, A; Kline, GA; Pasieka, JL; So, B, 2013) |
"Aldosterone excess has a direct negative effect on β-cell function in patients with PA." | 1.39 | Aldosterone excess impairs first phase insulin secretion in primary aldosteronism. ( Adolf, C; Beuschlein, F; Bidlingmaier, M; Fischer, E; Pallauf, A; Reincke, M; Seissler, J; Then, C, 2013) |
"Hypertension is a frequent complication of type 2 diabetes mellitus (DM) because of the close etiological relationship between these two diseases." | 1.39 | Prevalence and clinical characteristics of primary aldosteronism in Japanese patients with type 2 diabetes mellitus and hypertension. ( Akehi, Y; Murase, K; Nagaishi, R; Nomiyama, T; Takenoshita, H; Yanase, T, 2013) |
"Hyperkalemia is a potentially serious complication following adrenalectomy of aldosterone-producing adenomas (APA)." | 1.39 | Incidence and factors of post-adrenalectomy hyperkalemia in patients with aldosterone producing adenoma. ( Cheng, CJ; Chiang, WF; Lin, MY; Lin, SH; Sun, GH; Sung, CC; Wu, ST, 2013) |
"Rhodiola Sacra may prevent left ventricular remodeling in SHRs, which is probably attributed to blood pressure lowering and inhibition of RAS, especially myocardial RAS." | 1.39 | [Effect of Rhodiola Sacra on left ventricular remodeling and its mechanism in spontaneously hypertensive rats]. ( Chen, XP; Liu, K; Yang, R, 2013) |
"The spironolactone treatment group demonstrated significant increases in heart rate and cardiac output and a decrease in cardiac index compared to SHR controls." | 1.39 | Echocardiographic effects of eplerenone and aldosterone in hypertensive rats. ( Dostal, DE; Jewell, C; Song, J; Watson, LE, 2013) |
"Aldosterone values were adjusted statistically for age, sex, and the urinary sodium/creatinine ratio." | 1.39 | Bimodal aldosterone distribution in low-renin hypertension. ( Adlin, EV; Braitman, LE; Vasan, RS, 2013) |
"Primary aldosteronism (PA) is the most common etiology of endocrine hypertension (HTN), and recent prevalence studies suggest that it may be under-diagnosed." | 1.39 | Primary aldosteronism: emerging trends. ( Cheesman, KC; Galati, SJ; Hopkins, SM; Levine, AC; Zhuk, RA, 2013) |
"Hypertension is highly prevalent and remains poorly controlled." | 1.39 | Blood pressure control 1 year after referral to a hypertension specialist. ( Cohen, DL; Denker, MG; Haddad, DB; Townsend, RR, 2013) |
"Primary aldosteronism (PA) is the most common endocrine form of hypertension and may carry an increased risk of atrial flutter or fibrillation (AFF)." | 1.39 | Prospective appraisal of the prevalence of primary aldosteronism in hypertensive patients presenting with atrial flutter or fibrillation (PAPPHY Study): rationale and study design. ( Belfiore, A; Bernini, G; Caielli, P; Cipollone, F; Cottone, S; Ferri, C; Gallina, V; Giacchetti, G; Grassi, G; Leoni, L; Letizia, C; Maccario, M; Mantero, F; Morganti, A; Muiesan, ML; Olivieri, O; Palumbo, G; Pengo, M; Pessina, AC; Ragazzo, F; Rizzoni, D; Rossi, E; Rossi, GP; Seccia, TM; Sechi, L; Volpe, M, 2013) |
"Primary hyperaldosteronism is most commonly due to a solitary cortical adenoma." | 1.39 | Adrenal histologic findings show no difference in clinical presentation and outcome in primary hyperaldosteronism. ( Abraham, SB; Barak, S; Kebebew, E; Mathur, A; Nilubol, N; Quezado, M; Stratakis, CA; Webb, RC; Weisbrod, AB, 2013) |
"Primary aldosteronism (PA) is a common cause of secondary hypertension but the reported prevalence varies." | 1.39 | Screening for primary aldosteronism in a primary care unit. ( Hamberger, B; Thorén, M; Volpe, C; Wahrenberg, H, 2013) |
"Primary hyperaldosteronism is the most common cause of secondary hypertension." | 1.39 | Hypertension caused by primary hyperaldosteronism: increased heart damage and cardiovascular risk. ( Abad-Cardiel, M; Alvarez-Álvarez, B; Fernández, C; Fernández-Cruz, A; Luque-Fernandez, L; Martell-Claros, N, 2013) |
"Treatment with aldosterone did not alter mitochondrial respiratory function but accelerated Ca(2+)-induced MPT in SSM, but not IFM, compared with healthy old and young beagles." | 1.39 | Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs: effects of aging and long-term aldosterone infusion. ( Asemu, G; Cox, JW; Dabkowski, ER; Hecker, PA; Hoppel, CL; O'Connell, KA; Rastogi, S; Ribeiro, RF; Sabbah, HN; Shekar, KC; Stanley, WC; Xu, W, 2013) |
"Hyperaldosteronism was defined as a plasma renin activity of < 1 ng/mL/h and urinary aldosterone level of ≥ 12 μg/24 h." | 1.39 | Increased dietary sodium is related to severity of obstructive sleep apnea in patients with resistant hypertension and hyperaldosteronism. ( Batlouni, M; Calhoun, DA; Gordon, RD; Harding, SM; Oparil, S; Pimenta, E; Stowasser, M; Zhang, B, 2013) |
"Aldosterone is a major mineralocorticoid hormone that plays a key role in the regulation of electrolyte balance and blood pressure." | 1.39 | Structural insights into aldosterone synthase substrate specificity and targeted inhibition. ( Arrowsmith, CH; Edwards, AM; Gilep, AA; Park, HW; Shen, L; Strushkevich, N; Usanov, SA, 2013) |
" On the other hand, under the condition of Ang II-induced hypertension, administration of a hypotensive dosage of cilnidipine showed no effect on the plasma aldosterone levels, whereas a hypotensive dosage of nifedipine significantly increased the plasma aldosterone levels." | 1.38 | L/N-type calcium channel blocker suppresses reflex aldosterone production induced by antihypertensive action. ( Aritomi, S; Konda, T; Yoshimura, M, 2012) |
"Aldosterone (Aldo) is an important active hormone in the renin-angiotensin-aldosterone system and plays a vital role in the development of hypertension, heart failure and other cardiovascular diseases." | 1.38 | Endogenous aldosterone is involved in vascular calcification in rat. ( Cai, Y; Jia, LX; Qi, YF; Tang, CS; Wang, X; Wu, SY; Xiao, CS; Yu, YR, 2012) |
"Primary aldosteronism (PA) is the most frequent cause of secondary hypertension, and is associated with more prominent vascular stiffness and atherosclerosis." | 1.38 | Adrenalectomy improves increased carotid intima-media thickness and arterial stiffness in patients with aldosterone producing adenoma. ( Chen, A; Chueh, SC; Ho, YL; Lee, JK; Lin, LY; Lin, WC; Lin, YH; Lo, MT; Su, TC; Wang, PC; Wu, KD; Wu, VC; Wu, XM, 2012) |
"Spironolactone treatment significantly increased aldosterone levels in males and females independent of the sodium content of the diet." | 1.38 | Sex-specific effects of spironolactone on blood pressure in gonadectomized male and female Wistar rats. ( Bartel, C; Götz, F; Hofmann, PJ; Kienitz, T; Michaelis, M; Quinkler, M, 2012) |
"Currently, if hypertension is present in 20% of the population, PA will account for 2%; of these PA patients only 1% are ever screened, let alone diagnosed and treated, and the remaining 99% suboptimally treated, if at all." | 1.38 | Primary aldosteronism: are we missing the wood for the trees? ( Funder, JW, 2012) |
"Aldosterone has been linked to the deleterious cardiovascular effects of obesity in humans." | 1.38 | The development of hypertension and hyperaldosteronism in a rodent model of life-long obesity. ( Dorrance, AM; Fink, GD; Garver, H; Haywood, JR; Laimon-Thomson, EL; McClain, JL; Northcott, CA; Pires, PW; Rainey, WE; Rigsby, CS, 2012) |
"Myelolipomas are adrenal tumors composed of both adipose and hematopoietic tissues which are rarely associated with primary aldosteronism (PA)." | 1.38 | A case of myelolipoma with bilateral adrenal hyperaldosteronism cured after unilateral adrenalectomy. ( Arai, H; Fujii, T; Fukuda, Y; Honda, K; Inuzuka, M; Kanamoto, N; Kojima, K; Kondo, E; Mikami, Y; Miura, M; Nakao, K; Sasano, H; Sone, M; Sonoyama, T; Tamura, N; Taura, D; Ueda, Y; Yamada, G; Yamashita, Y; Yasoda, A, 2012) |
"Amiloride treatment also reduced high blood pressure caused by the high-salt diet in these mice." | 1.38 | Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice. ( Chen, S; Cui, Y; Jiang, J; Peng, J; Shen, J; Wang, W; Wu, Q, 2012) |
"The prevalence of primary aldosteronism in unselected hypertensive patients is currently unknown." | 1.38 | Screening for primary aldosteronism in hypertensive subjects: results from two German epidemiological studies. ( Beuschlein, F; Bidlingmaier, M; Biffar, R; Döring, A; Felix, SB; Friedrich, N; Hannemann, A; Manolopoulou, J; Meisinger, C; Nauck, M; Peters, A; Reincke, M; Rettig, R; Seissler, J; Spyroglou, A; Völzke, H; Wallaschofski, H; Wichmann, HE, 2012) |
"Hyperaldosteronism combined with hypertension favored the macrophage infiltration (CD68(+) cells) in heart, and enhanced the mRNA level of monocyte chemoattractant protein 1, osteopontin, and galectin 3." | 1.38 | Aldosterone inhibits antifibrotic factors in mouse hypertensive heart. ( Azibani, F; Benard, L; Carrier, L; Chatziantoniou, C; Delcayre, C; Fazal, L; Launay, JM; Merval, R; Polidano, E; Samuel, JL; Schlossarek, S; Tournoux, F, 2012) |
"Arterial hypertension (AH) induces cardiac hypertrophy and reactivation of "fetal" gene expression." | 1.38 | Aldosterone inhibits the fetal program and increases hypertrophy in the heart of hypertensive mice. ( Azibani, F; Carrier, L; Chatziantoniou, C; Coutance, G; Delcayre, C; Devaux, Y; Fazal, L; Launay, JM; Merval, R; Polidano, E; Samuel, JL; Schlossarek, S; Solal, AC, 2012) |
"Moreover, aldosterone-producing adrenocortical carcinomas without hypertension are exceedingly rare, with only two previously reported cases." | 1.38 | Aldosterone-producing adrenocortical carcinoma without hypertension. ( Bae, SB; Kim, SJ; Kim, YJ; Seo, SW; Song, MS, 2012) |
"Hypertension is characterized by left ventricular (LV) hypertrophy (LVH)." | 1.38 | Interferon-γ ablation exacerbates myocardial hypertrophy in diastolic heart failure. ( Baid, S; Garcia, AG; Heo, J; Murthy, NR; Ouchi, N; Sam, F; Wilson, RM, 2012) |
"Primary hyperaldosteronism or Conn syndrome is the syndrome formed from the triad of hypertension, hypokalemia, and metabolic alkalosis." | 1.38 | Sixteen years experience in six cases of Conn syndrome in Jakarta. ( Siregar, P, 2012) |
"Primary aldosteronism caused by an aldosterone producing adrenal tumor/aldosteronoma (APA), is a potentially curable form of hypertension, via unilateral adrenalectomy." | 1.38 | Persistent hypertension after adrenalectomy for an aldosterone-producing adenoma: weight as a critical prognostic factor for aldosterone's lasting effect on the cardiac and vascular systems. ( Carter, Y; Chen, H; Roy, M; Sippel, RS, 2012) |
"Obesity is a major risk factor for hypertension." | 1.38 | Increasing peripheral insulin sensitivity by protein tyrosine phosphatase 1B deletion improves control of blood pressure in obesity. ( Ali, MI; Belin de Chantemèle, EJ; Fulton, DJ; Mintz, JD; Rainey, WE; Stepp, DW; Tremblay, ML, 2012) |
"Insulin resistance was calculated using the homeostasis model assessment (HOMA-IR)." | 1.37 | Cardiovascular correlates of insulin resistance in normotensive and hypertensive African Americans. ( Grim, CE; Kidambi, S; Kotchen, JM; Kotchen, TA; Krishnaswami, S, 2011) |
"Aldosterone treatment did not modify NO or TxB(2) release, but it did increase superoxide anion and 6-keto-PGF(1alpha) release in mesenteric resistance arteries from both strains." | 1.37 | Aldosterone alters the participation of endothelial factors in noradrenaline vasoconstriction differently in resistance arteries from normotensive and hypertensive rats. ( Avendaño, MS; Balfagón, G; Blanco-Rivero, J; Salaíces, M; Sastre, E; Velázquez, K; Xavier, FE; Yela, R, 2011) |
"To evaluate the prevalence of primary aldosteronism (PA) in newly diagnosed and untreated hypertensive patients in primary care using the aldosterone/renin ratio (ARR), and to assess clinical and biochemical characteristics in patients with high and normal ARR." | 1.37 | Primary aldosteronism among newly diagnosed and untreated hypertensive patients in a Swedish primary care area. ( Bergenfelz, A; Isaksson, A; Nerbrand, C; Valdemarsson, S; Westerdahl, C, 2011) |
"Current data on primary aldosteronism (PA) from Asian populations are scarce." | 1.37 | Verification and evaluation of aldosteronism demographics in the Taiwan Primary Aldosteronism Investigation Group (TAIPAI Group). ( Chang, CC; Chang, HW; Chu, TS; Chueh, SC; Huang, KH; Kao, TW; Kuo, CC; Lai, CF; Lee, TY; Lin, CY; Lin, WC; Lin, YH; Lu, CC; Tsai, CW; Wang, SM; Wang, WJ; Wu, KD; Wu, MS; Wu, VC; Yang, WS, 2011) |
"Obesity has been recognized as an independent risk factor for arterial hypertension." | 1.37 | Arterial hypertension in obesity: relationships with hormone and anthropometric parameters. ( De Pergola, G; Guida, P; Nardecchia, A; Silvestris, F, 2011) |
"Familial hyperaldosteronism type 1 is an autosomal dominant disorder attributed to a chimeric CYP11B1/CYP11B2 gene (CG)." | 1.37 | Frequency of familial hyperaldosteronism type 1 in a hypertensive pediatric population: clinical and biochemical presentation. ( Aglony, M; Avalos, C; Avila, A; Bancalari, R; Bolte, L; Brinkmann, K; Campino, C; Carvajal, CA; Fardella, CE; García, H; Giadrosich, V; Inostroza, A; Loureiro, C; Martínez-Aguayo, A; Mericq, V; Perez, V; Rocha, A; Trejo, P, 2011) |
"Glucocorticoid-remediable aldosteronism (GRA) is caused by the presence of a chimeric gene originating from an unequal cross-over between the CYP11B1 and CYP11B2 genes." | 1.37 | Diagnosis of glucocorticoid-remediable aldosteronism in hypertensive children. ( Haag, C; Kamrath, C; Maser-Gluth, C; Schulze, E, 2011) |
"1." | 1.37 | Association of the aldosterone synthase gene -344T>C polymorphism with essential hypertension and glucose homeostasis: a case-control study in a Han Chinese population. ( Chen, HY; Gao, X; Li, XM; Ling, Y; Liu, Y; Lu, DR; Lu, ZQ; Yi, QL, 2011) |
"Hypertension is the most common cardiovascular disease worldwide and is a major cause of morbidity and mortality." | 1.37 | Plasma catecholamines in Nigerians with primary hypertension. ( Adebiyi, AA; Akinosun, OM; Falase, AO; Nwafor, CE, 2011) |
"Hyperaldosteronism was classified as an aldosterone/renin ratio (ARR) ≥ 30." | 1.37 | Resistant hypertension and undiagnosed primary hyperaldosteronism detected by use of a computerized database. ( Garcia, EA; Lopez, JR; Meier, JL; Siegel, D; Swislocki, AL, 2011) |
"Hypertension is a leading contributor to cardiovascular mortality worldwide." | 1.37 | Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway. ( Ando, K; Ayuzawa, N; Fujita, T; Ishikawa, A; Ishizawa, K; Kawarazaki, H; Kawarazaki, W; Miyoshi, J; Mu, S; Muraoka, K; Nagase, M; Shibata, S; Shimosawa, T; Takai, Y; Takeuchi, M; Yoshida, S, 2011) |
"Primary aldosteronism (PA) is associated with a higher incidence of cardiovascular events, probably through mineralocorticoid receptor (MR)-dependent endothelial cell dysfunction, in comparison with essential hypertension (EH)." | 1.37 | Endothelial progenitor cells in primary aldosteronism: a biomarker of severity for aldosterone vasculopathy and prognosis. ( Chen, JW; Chen, YL; Huang, PH; Kuo, CC; Kuo, YS; Lee, BC; Liang, CJ; Lin, SJ; Lin, SL; Lin, YH; Lo, SC; Sun, YY; Tsai, CT; Wu, EL; Wu, KD; Wu, VC, 2011) |
"Spironolactone treatment reversed all the above effects." | 1.37 | A role for cardiotrophin-1 in myocardial remodeling induced by aldosterone. ( Cachofeiro, V; Díez, J; Fortuno, MA; Lahera, V; López-Andrés, N; Martin-Fernandez, B; Rossignol, P; Zannad, F, 2011) |
"Resistant hypertension has evolved as an important global health care problem." | 1.37 | What is the role of aldosterone excess in resistant hypertension and how should it be investigated and treated? ( Sica, DA, 2011) |
"Aldosterone plays a role in hypertension, and hypertension is prevalent in patients with insulin resistance." | 1.37 | Plasma aldosterone levels and development of insulin resistance: prospective study in a general population. ( Adachi, H; Enomoto, M; Esaki, E; Fukami, A; Hirai, Y; Imaizumi, T; Jacobs, DR; Kasahara, A; Kumagae, S; Kumagai, E; Nanjo, Y; Ogata, K; Ohbu-Murayama, K; Otsuka, M; Tsukagawa, E; Yokoi, K; Yoshikawa, K, 2011) |
"Primary aldosteronism (PA) is a possible cause of endocrine hypertension." | 1.37 | [Aldosterone/renin ratio in the diagnosis of primary aldosteronism]. ( Catay, E; Honnorat, E; Izquierdo, A; Popescu, BM; Ríos, MC; Rodríguez Cuimbra, S; Sotelo, M, 2011) |
"S-Aldosterone was normalized." | 1.36 | Long-term effects of surgical correction of adrenal hyperplasia and adenoma causing primary aldosteronism. ( Andreasson, S; Botling, J; Hägg, A; Hellman, P; Hennings, J; Sundin, A, 2010) |
"Metabolic syndrome was defined according to ATPIII criteria." | 1.36 | Metabolic syndrome in primary aldosteronism and essential hypertension: relationship to adiponectin gene variants. ( Agostinelli, L; Boscaro, M; Di Mattia, D; Giacchetti, G; Rilli, S; Ronconi, V; Turchi, F, 2010) |
"Insulin resistance is associated with nonalcoholic fatty liver disease (NAFLD) and may play a role in its pathophysiology." | 1.36 | Nonalcoholic fatty liver disease in primary aldosteronism: a pilot study. ( Bertello, C; Catena, C; Dalla Pozza, A; Ermani, M; Fabris, B; Fallo, F; Mulatero, P; Sabato, N; Sechi, LA; Sonino, N; Tecchio, M; Tona, F, 2010) |
"Hypertension was induced in Cyp1a1-Ren-2 rats through dietary administration of the natural xenobiotic indole-3-carbinol (0." | 1.36 | Inappropriately high circulating and intrarenal angiotensin II levels during dietary salt loading exacerbate hypertension in Cyp1a1-Ren-2 transgenic rats. ( Bürgelová, M; Cervenka, L; Erbanová, M; Husková, Z; Kramer, HJ; Mullins, JJ; Opocenský, M; Thumová, M; Vanourková, Z, 2010) |
"After a positive screening, primary aldosteronism diagnosis needs confirmation by an inhibitory test such as intravenous saline load (ivSLT)." | 1.36 | Effects of female sex hormones and contraceptive pill on the diagnostic work-up for primary aldosteronism. ( Chiecchi, L; Corrocher, R; Franchi, M; Guarini, P; Guidi, GC; Memmo, A; Olivieri, O; Pavan, C; Pizzolo, F; Raffaelli, R, 2010) |
"In 22 patients with unilateral primary aldosteronism (UPA), unilateral laparoscopic adrenalectomy (ADX) not only corrected hypokalemia and led to cure or improvement of hypertension, but also significantly improved quality of life (QOL)." | 1.36 | Improved quality of life, blood pressure, and biochemical status following laparoscopic adrenalectomy for unilateral primary aldosteronism. ( Gordon, RD; Kogovsek, C; Robson, D; Stowasser, M; Sukor, N, 2010) |
"Although hypokalemia is a common clinical problem, symptoms generally do not become manifest unless the serum potassium (K) falls rapidly." | 1.36 | [Clinical characteristics of five elderly patients with severe hypokalemia induced by glycyrrhizin derivatives]. ( Hatanaka, M; Kadoya, H; Matsuda, J; Namba, T; Takahashi, A; Takeji, M; Yamamoto, T; Yamauchi, A, 2010) |
"Aldosterone is a prerequisite for this action." | 1.36 | Pathogenesis of hypertension: interactions among sodium, potassium, and aldosterone. ( Büssemaker, E; Hausberg, M; Hillebrand, U; Oberleithner, H; Pavenstädt, H, 2010) |
"Azelnidipine treatment in drug-naïve (DN) cases significantly decreased systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR)." | 1.36 | Plasma renin activity and aldosterone concentration are not altered by the novel calcium channel antagonist, azelnidipine, in hypertensive patients. ( Araki, E; Goto, R; Kondo, T; Miyamura, N; Ono, K; Sonoda, K; Takaki, Y; Yasuda, T; Yatsuda, R, 2010) |
"Resistant hypertension was defined as the failure to control systolic and/or diastolic BP despite at least three different classes of antihypertensive agents, including a diuretic." | 1.36 | RGS2 expression and aldosterone: renin ratio modulate response to drug therapy in hypertensive patients. ( Calò, LA; Ceolotto, G; Macchini, L; Papparella, I; Realdi, A; Sartori, M; Semplicini, A; Strapazzon, G, 2010) |
"Felodipine has a protective effect on the myocardium and kidney as evidenced by decreased perivascular inflammation, myocardial necrosis and fibrosis." | 1.36 | Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats. ( Franco, M; Janicki, JS; Matsubara, BB; Matsubara, LS, 2010) |
"Primary aldosteronism (PA) is a common form of secondary hypertension." | 1.36 | The prevalence of metabolic syndrome and its components in two main types of primary aldosteronism. ( Dvoráková, J; Holaj, R; Masek, M; Petrák, O; Rosa, J; Somlóová, Z; Strauch, B; Vlková, J; Wichterle, D; Widimský, J; Zelinka, T, 2010) |
"Primary aldosteronism (PA) is a frequent cause of secondary hypertension and is amenable to surgical intervention when it is caused by aldosterone-producing adenoma (APA)." | 1.36 | Predictors of resolution of hypertension after adrenalectomy in patients with aldosterone-producing adenoma. ( Kim, RM; Lee, J; Soh, EY, 2010) |
"Aldosterone and LVH were investigated in 240 and 110 subjects respectively." | 1.36 | Association of HSD3B1 and HSD3B2 gene polymorphisms with essential hypertension, aldosterone level, and left ventricular structure. ( Aoi, N; Izumi, Y; Matsumoto, K; Nakayama, T; Sato, M; Sato, N; Shimodaira, M; Soma, M, 2010) |
"Aldosterone has been correlated with increased oxidative stress, endothelial inflammation, and fibrosis, particularly in patients with heart disease." | 1.36 | Increased levels of oxidative stress, subclinical inflammation, and myocardial fibrosis markers in primary aldosteronism patients. ( Becerra, E; Carvajal, CA; Fardella, CE; García, L; Jalil, J; Lavandero, S; Mellado, R; Mosso, L; Ocaranza, MP; Solis, M; Stehr, CB, 2010) |
"Hyperaldosteronism (PRA < 1 ng x mL(-1) x h(-1) and UAldo > or = 12 microg/24-h) prevalence was 28% and OSA prevalence was 77%." | 1.36 | Severity of obstructive sleep apnea is related to aldosterone status in subjects with resistant hypertension. ( Ahmed, MI; Calhoun, DA; Cofield, SS; Gaddam, KK; Gonzaga, CC; Harding, SM; Oparil, S; Pimenta, E; Thomas, SJ, 2010) |
"Glucocorticoid-remediable aldosteronism (GRA) is an autosomal-dominant inheritable form of hyperaldosteronism with early onset hypertension." | 1.36 | Genetic analyses of the chimeric CYP11B1/CYP11B2 gene in a Korean family with glucocorticoid-remediable aldosteronism. ( Jang, HW; Jo, YS; Kim, MK; Kim, SY; Lee, IS; Lee, JH; Lee, YH, 2010) |
"Primary aldosteronism is more common than previously recognized but much less common than most experts in this arena have recently stated." | 1.36 | Current diagnosis and treatment of primary aldosteronism. ( Kaplan, NM, 2010) |
"Resistant hypertension is a common clinical problem and greatly increases the risk of target organ damage." | 1.35 | Characterization of resistant hypertension: association between resistant hypertension, aldosterone, and persistent intravascular volume expansion. ( Aban, I; Calhoun, DA; Gaddam, KK; Nishizaka, MK; Oparil, S; Pimenta, E; Pratt-Ubunama, MN, 2008) |
"The diagnosis of primary hyperaldosteronism due to microadenoma or unilateral adrenal hyperplasia can be challenging, since hypokalaemic alkalosis, high plasma aldosterone and a definite adenoma on imaging may all be absent." | 1.35 | Primary hyperaldosteronism due to adrenal microadenoma: a curable cause of refractory hypertension. ( Appleton, DS; Brown, MJ; Coghill, S; Jamieson, N; Lomas, DJ; Myint, KS; Taylor, KP; Watts, M, 2008) |
"A clear reduction of BP values was recorded after both the first and the second month of treatment with kanrenoate, with the maximal effect obtained when the dosage titration at 100 mg/day was accomplished." | 1.35 | Menopause not aldosterone-to-renin ratio predicts blood pressure response to a mineralocorticoid receptor antagonist in primary care hypertensive patients. ( Blengio, GS; Ciacciarelli, A; Corrocher, R; Falcone, S; Olivieri, O; Pizzolo, F; Signorelli, D, 2008) |
"Primary aldosteronism (PA) represents a clinical model useful in assessing the effect of aldosterone increase on LVM." | 1.35 | Inappropriate left ventricular mass in patients with primary aldosteronism. ( Agabiti-Rosei, C; Agabiti-Rosei, E; Aggiusti, C; Belotti, E; Castellano, M; Galbassini, G; Monteduro, C; Muiesan, ML; Paini, A; Rizzoni, D; Salvetti, M, 2008) |
"Weight loss is associated with reduction of blood pressure and of PRA and aldosterone levels in obese hypertensive subjects." | 1.35 | Effect of weight loss through laparoscopic gastric banding on blood pressure, plasma renin activity and aldosterone levels in morbid obesity. ( Dall'Asta, C; Folli, F; Manunta, P; Marchi, M; Paganelli, M; Pizzocri, P; Pontiroli, AE; Vedani, P, 2009) |
"Considering the role of aldosterone in diabetic nephropathy, genetic polymorphism of this gene may contribute to the development and progression of diabetic nephropathy." | 1.35 | Polymorphism of the aldosterone synthase gene is not associated with progression of diabetic nephropathy, but associated with hypertension in type 2 diabetic patients. ( Cha, DR; Kang, YS; Kim, HK; Ko, GJ; Lee, MH; Song, HK, 2008) |
"Recent data suggest that primary aldosteronism is found in about 10% of hypertensive patients managed in primary care and diagnosed in about 20% of treated but uncontrolled hypertensive patients." | 1.35 | [Primary hyperaldosteronism in hypertension]. ( Girerd, X, 2008) |
"Primary aldosteronism (PA) may account for as much as 6-20% of cases of refractory hypertension referred to hypertension clinics." | 1.35 | The cutoff value of aldosterone-to-renin ratio for the diagnosis of primary aldosteronism in patients taking antihypertensive medicine. ( Fukuchi, K; Horio, T; Iwanaga, Y; Kamide, K; Kawano, Y; Nakahama, H; Nakamura, S; Nakata, H; Niizuma, S; Yoshihara, F, 2008) |
"Both fibrinogen and PAI-1 were independent predictors of the presence of organ damage and their inclusion in a multivariate model eliminated PRA and aldosterone as independent predictors." | 1.35 | Relationship of plasma renin with a prothrombotic state in hypertension: relevance for organ damage. ( Casanova-Borca, A; Catena, C; Chiuch, A; Colussi, G; Di Fabio, A; Nadalini, E; Novello, M; Sechi, LA; Uzzau, A, 2008) |
"Aldosterone promotes renal fibrosis via the mineralocorticoid receptor (MR), thus contributing to hypertension-induced nephropathy." | 1.35 | Hypertension-induced renal fibrosis and spironolactone response vary by rat strain and mineralocorticoid receptor gene expression. ( Camp, JR; Cavallari, LH; Fashingbauer, LA; Geenen, DL; King, ST, 2008) |
"Treatment with camostat mesilate or FOY-251 decreased equivalent current (Ieq) in M-1 cells in a dose-dependent manner and inhibited the protease activity of prostasin in vitro." | 1.35 | Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension. ( Adachi, M; Kakizoe, Y; Kitamura, K; Ko, T; Maekawa, A; Miyoshi, T; Shiraishi, N; Tomita, K; Wakida, N, 2009) |
"Findings suggested that primary hyperaldosteronism should be considered as a possible cause in ferrets with hypokalemia, hypertension, and an adrenal gland mass." | 1.35 | Primary hyperaldosteronism in a domestic ferret with an adrenocortical adenoma. ( Desmarchelier, M; Dunn, M; Lair, S; Langlois, I, 2008) |
"Until recently, primary hyperaldosteronism was considered a rare cause of secondary hypertension." | 1.35 | Prevalence of primary hyperaldosteronism in a systemic arterial hypertension league. ( Faria, Mdos S; Figueiredo Neto, JA; Lopes, Mde C; Memória, EV; Oliveira, TC; Ribeiro, MJ; Salgado Filho, N, 2009) |
"To evaluate the prevalence of left ventricular hypertrophy (LVH) and left ventricular geometry in a group of 293 hypertensive patients with stage 2-5 chronic kidney disease (CKD), compared with 289 essential hypertensive patients with normal renal function." | 1.35 | Left ventricular hypertrophy and geometry in hypertensive patients with chronic kidney disease. ( Cerasola, G; Cottone, S; Cusimano, P; Mulè, G; Nardi, E; Palermo, A, 2009) |
"Primary aldosteronism (PA) is a secondary hypertension characterized by autonomous aldosterone hypersecretion from adrenocortical adenoma and/or hyperplasia." | 1.35 | Endothelial dysfunction is related to aldosterone excess and raised blood pressure. ( Hirata, Y; Tsuchiya, K; Yoshimoto, T, 2009) |
"Adrenal masses in Gardner's syndrome are rare, and few have displayed clinical manifestations." | 1.35 | Hyperaldosteronism in an adolescent with Gardner's syndrome. ( Felner, EI; Gow, K; Taweevisit, M, 2009) |
"The hyperaldosteronism of apc(Min/+) mice was paralleled by significantly elevated plasma volume and blood pressure." | 1.35 | Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC. ( Bhandaru, M; Kempe, DS; Kuhl, D; Lang, F; Rexhepaj, R; Rotte, A, 2009) |
"Primary aldosteronism (PA) is the most common secondary cause of hypertension that has recently been implicated in alterations of the immune system and progression of cardiovascular disease." | 1.35 | Primary aldosteronism can alter peripheral levels of transforming growth factor beta and tumor necrosis factor alpha. ( Carvajal, CA; Castillo, CR; Contreras, FJ; Fardella, CE; Herrada, AA; Kalergis, AM; Mosso, LM; Stehr, CB, 2009) |
"Primary aldosteronism (PA) is caused by autonomous hypersecretion of aldosterone from the adrenal cortex, classically from an adenoma, resulting in sodium and water retention, hypokalaemia and raised blood pressure." | 1.35 | Atrial fibrillation in primary aldosteronism. ( Beevers, DG; Karthikeyan, VJ; Lip, GY; Watson, T, 2009) |
"Normokalaemia does not exclude primary aldosteronism as the underlying cause of hypertension." | 1.35 | [Normokalaemic primary aldosteronism due to an aldosterone-producing adrenal adenoma--Case 06/2009]. ( Guthoff, M; Horger, M; Kirchhoff, K; Kurth, R; Müssig, K; Schnauder, G, 2009) |
"A major adverse effect of these treatments is hypertension, suggesting a critical role for VEGF in blood pressure (BP) regulation." | 1.35 | Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression. ( Coffman, TM; Facemire, CS; Griffiths, R; Hurwitz, H; Nixon, AB, 2009) |
"Endocrine hypertension is rare, but frequently refractory." | 1.35 | [Endocrine hypertension]. ( Ibsen, H; Poulsen, PL, 2009) |
"Insulin resistance was estimated by the homeostasis model assessment." | 1.35 | Aldosterone contributes to blood pressure variance and to likelihood of hypertension in normal-weight and overweight African Americans. ( Grim, CE; Kidambi, S; Kotchen, JM; Kotchen, TA; Krishnaswami, S, 2009) |
"The hypertension was not different and virtually superimposable in WT vs." | 1.35 | The role of aldosterone in mediating the dependence of angiotensin hypertension on IL-6. ( Brands, MW; Cannon, JG; Schreihofer, DA; Sturgis, LC, 2009) |
"The prevalence of primary aldosteronism has increased since many patients who were previously considered as being affected by low renin essential hypertension are actually satisfying the new diagnostic criteria using plasma aldosterone/ plasma renin activity (PRA) ratio." | 1.35 | Some considerations about evolution of idiopathic primary aldosteronism. ( Armanini, D; Fiore, C, 2009) |
"Hypertensive nephrosclerosis is characterized by activation of the renin-angiotensin-aldosterone system in combination with an inflammatory response characterized by an infiltration of T-cells and mononuclear cells, which release proinflammatory cytokines like IL-1beta/TNFalpha." | 1.35 | Synergistic induction of osteopontin by aldosterone and inflammatory cytokines in mesangial cells. ( Gauer, S; Geiger, H; Goppelt-Struebe, M; Hauser, IA; Holzmann, Y; Obermüller, N, 2008) |
"Liddle's syndrome is an autosomal dominant form of human hypertension, caused by gain-of-function mutations of the epithelial sodium channel (ENaC) which is expressed in aldosterone target tissues including the distal colon." | 1.35 | Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome. ( Bertog, M; Cuffe, JE; Hartner, A; Hilgers, KF; Hummler, E; Korbmacher, C; Porst, M; Pradervand, S; Rossier, BC, 2008) |
"Patients with primary aldosteronism were compared with patients with essential hypertension and were treated to reach a blood pressure of less than 140/90 mm Hg." | 1.35 | Cardiovascular outcomes in patients with primary aldosteronism after treatment. ( Baroselli, S; Catena, C; Chiuch, A; Colussi, G; Lapenna, R; Nadalini, E; Sechi, LA, 2008) |
"The aldosterone level was comparable in both groups." | 1.35 | Diastolic dysfunction is associated with insulin resistance, but not with aldosterone level in normotensive offspring of hypertensive families. ( Poredos, P; Trojar, A; Zeljko, T; Zizek, B, 2008) |
"In patients with primary aldosteronism, as a whole group, the cut-off value of 69 corresponded to the best compromise value between sensitivity (96%) and specificity (85%), with and without PRA adjustment." | 1.35 | Plasma and urine aldosterone to plasma renin activity ratio in the diagnosis of primary aldosteronism. ( Bardini, M; Bernini, G; Bernini, M; Berti, P; Miccoli, P; Moretti, A; Orlandini, C; Salvetti, A; Taurino, C, 2008) |
"Aldosterone is a mineral corticoid hormone that is produced in response to angiotensin-II, and like angiotensin-II, stimulates inflammation, oxidative stress, and fibrosis by activating nuclear factor-kappaB and activating protein-1." | 1.35 | Crosstalk between the heme oxygenase system, aldosterone, and phospholipase C in hypertension. ( Jadhav, A; Lane, N; Ndisang, JF, 2008) |
"ACTH-induced-hypertension is commonly employed as a model of stress-related hypertension, and despite extensive investigation, the mechanisms underlying elevated blood pressure (BP) are not well understood." | 1.35 | ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit. ( Dostanic-Larson, I; Lasko, V; Lingrel, JB; Loreaux, EL; Lorenz, JN; Paul, RJ; Schnetzer, JR, 2008) |
"Primary aldosteronism (PA) is characterized by the onset of both cardiac and gluco-metabolic alterations." | 1.34 | Aldosterone as a key mediator of the cardiometabolic syndrome in primary aldosteronism: an observational study. ( Agostinelli, L; Boscaro, M; Giacchetti, G; Mantero, F; Rilli, S; Ronconi, V; Turchi, F, 2007) |
"Hypertension was defined as average ambulatory blood pressure >130/85 mm Hg." | 1.34 | Association of adrenal steroids with hypertension and the metabolic syndrome in blacks. ( Grim, CE; Kidambi, S; Kotchen, JM; Kotchen, TA; Mao, J; Raff, H; Singh, RJ, 2007) |
"Primary aldosteronism accompanied by hypokalemia is a cause of secondary hypertension." | 1.34 | Hypertension associated with rhabdomyolysis. ( Aslanidis, S; Douma, S; Kartali, N; Papaefthimiou, P; Petidis, K; Zamboulis, C, 2007) |
"Aldosterone plays essential roles in body fluid and electrolyte homeostasis and blood pressure." | 1.34 | Polymorphism of CYP11B2 determines salt sensitivity in Japanese. ( Iwai, N; Kajimoto, K; Takashima, N; Tomoike, H, 2007) |
"Essential hypertension is a disease multifactorially triggered by genetic and environmental factors." | 1.34 | Analysis of renin-angiotensin-aldosterone system gene polymorphisms in resistant hypertension. ( Barros, M; Bittencourt, I; Cabello, PH; Cordovil, IL; Dolinsky, LC; Freitas, SR; Lima, AB; Moura-Neto, RS, 2007) |
"Primary aldosteronism (PA) has been considered a rare cause of hypertension." | 1.34 | Prevalence of primary aldosteronism among unselected hypertensive patients: a prospective study based on the use of an aldosterone/renin ratio above 25 as a screening test. ( Fogari, E; Fogari, R; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A, 2007) |
"Primary aldosteronism (PA) represents an important cause of secondary hypertension, potentially curable, and it has been receiving particular attention due to its increasing prevalence, after the beginning of the use of plasma aldosterone concentration to plasma renin activity ratio as a screening method." | 1.34 | [Primary aldosteronism caused by aldosteronoma: problems in the etiologic diagnosis]. ( Brandão Neto, RA; Danilovic, DL; Freire, DS; Lucon, AM; Paraíba, DB; Pereira, MA, 2007) |
"Treatment of primary aldosteronism decreased blood pressure (BP) and restored normal potassium concentrations." | 1.34 | Renal cysts and hypokalemia in primary aldosteronism: results of long-term follow-up after treatment. ( Baroselli, S; Bazzocchi, M; Catena, C; Chiuch, A; Colussi, GL; Lapenna, R; Nadalini, E; Novello, M; Sechi, LA, 2007) |
"Aldosterone is an important cardiovascular hormone; 15% of hypertensive subjects have alteration in aldosterone regulation, defined by a raised ratio of aldosterone to renin (ARR)." | 1.34 | Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study. ( Brown, M; Caulfield, M; Clayton, D; Connell, JM; Davies, E; Dominiczak, AF; Farrall, M; Fraser, R; Freel, EM; Friel, EC; Ingram, M; Munroe, P; Samani, NJ; Webster, J, 2007) |
"Primary hyperaldosteronism is not as uncommon as previously thought, but its prevalence depends on the selected population." | 1.34 | Resistant hypertension: a methodological approach to diagnosis and treatment. ( Tamimi, NA, 2007) |
"Hypertension was less common in the JV than in Irbid City (9." | 1.34 | A comparative study of plasma renin activity, aldosterone and atrial natriuretic hormone between normotensive and hypertensive people living at below sea level altitude (Jordan Valley) and those residing at moderate altitude above. ( El-Migdadi, F, 2007) |
"The majority of infants do not require treatment for hypertension by 6 months of age." | 1.34 | Antenatal and postnatal risk factors for neonatal hypertension and infant follow-up. ( Falk, MC; Kent, AL; Seliem, WA; Shadbolt, B, 2007) |
"Primary aldosteronism (PA) is the most common secondary cause of hypertension and recently has been implicated as a cause of impaired glucose tolerance." | 1.34 | A possible association between primary aldosteronism and a lower beta-cell function. ( Artigas, RA; Carvajal, CA; Castillo, CR; Fardella, CE; Maiz, A; Mosso, LM; Ortiz, EH, 2007) |
"Aldosterone excess has been reported to be a common cause of resistant hypertension." | 1.34 | Aldosterone excess and resistance to 24-h blood pressure control. ( Calhoun, DA; Cofield, SS; Gaddam, KK; Nishizaka, MK; Oparil, S; Pimenta, E; Pratt-Ubunama, MN, 2007) |
"Fifty-four patients with primary aldosteronism were enrolled in a prospective study and were followed for a mean of 6." | 1.34 | Long-term cardiac effects of adrenalectomy or mineralocorticoid antagonists in patients with primary aldosteronism. ( Catena, C; Chiuch, A; Colussi, G; Gianfagna, P; Lapenna, R; Nadalini, E; Sechi, LA, 2007) |
"There is a high prevalence for primary hyperaldosteronism (PHA) in hypertensive patients." | 1.34 | [Comparison of adrenal imaging and selective adrenal vein sampling in primary hyperaldosteronism]. ( Adams, S; Hahn, K; Kokulinsky, P; Liermann, D; Rump, LC; Stegbauer, J; Vonend, O, 2007) |
"Thus, a reliable screening test for primary hyperaldosteronism (PA) is essential to avoid unnecessary diagnostic procedures to this population." | 1.34 | The aldosterone to renin ratio in the evaluation of patients with incidentally detected adrenal masses. ( Botoula, E; Effraimidis, G; Effremidis, G; Gavalas, N; Szabo, A; Thalassinos, NC; Tzanela, M; Valatsou, A; Vassiliadi, D, 2007) |
"Primary hyperaldosteronism (PH), resulting in hypokalaemic hypertension, may be due to an aldosterone-producing adenoma (APA) or bilateral zona glomerulosa hyperplasia." | 1.34 | Prospective evaluation and characteristics of patients with suspected primary hyperaldosteronism. ( Boyne, MS; McKenzie, CA; Wright-Pascoe, R, 2007) |
"Here we describe a 13-yr-old girl with primary hyperaldosteronism secondary to aldosterone-secreting adenoma." | 1.34 | An additional child case of an aldosterone-producing adenoma with an atypical presentation of peripheral paralysis due to hypokalemia. ( Acikalin, MF; Dinleyici, EC; Dogruel, N; Ilhan, H; Oztelcan, B; Tokar, B, 2007) |
"Adult hypertension was induced by maternal low-protein diet during the second half of gestation." | 1.33 | Postnatal modulation of prenatally programmed hypertension by dietary Na and ACE inhibition. ( Manning, J; Vehaskari, VM, 2005) |
"Recent reports suggesting that primary aldosteronism (PA) is more common than historically thought have often relied on use of the plasma aldosterone concentration (PAC) to plasma renin activity (PRA) ratio (ARR) to identify patients with PA." | 1.33 | Validity of plasma aldosterone-to-renin activity ratio in African American and white subjects with resistant hypertension. ( Calhoun, DA; Cofield, S; Nishizaka, MK; Pratt-Ubunama, M; Zaman, MA, 2005) |
"Treatment with aldosterone did not modify blood pressure levels in any strain." | 1.33 | Participation of prostacyclin in endothelial dysfunction induced by aldosterone in normotensive and hypertensive rats. ( Aras-Lopez, R; Balfagón, G; Blanco-Rivero, J; Cachofeiro, V; Ferrer, M; Lahera, V; Márquez-Rodas, I; Salaices, M; Xavier, FE, 2005) |
"Aldosterone plays an important role in the pathogenesis of hypertension." | 1.33 | c-Src-dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats. ( Callera, GE; He, Y; Montezano, AC; Schiffrin, EL; Tostes, RC; Touyz, RM; Yogi, A, 2005) |
"Despite advances in treatment, twin-to-twin transfusion syndrome (TTTS) still carries a high risk for perinatal mortality and morbidity." | 1.33 | Paradoxic activation of the renin-angiotensin system in twin-twin transfusion syndrome: an explanation for cardiovascular disturbances in the recipient. ( Delezoide, AL; Dommergues, M; Fisk, NM; Gubler, MC; Madelenat, P; Mahieu-Caputo, D; Martinovic, J; Meulemans, A; Muller, F, 2005) |
"Screening for primary hyperaldosteronism (PHA) is often indicated in individuals with resistant hypertension or hypokalaemia." | 1.33 | Prevalence of primary hyperaldosteronism in mild to moderate hypertension without hypokalaemia. ( Brown, NJ; Conlin, PR; Hopkins, PN; Jeunemaitre, X; Raji, A; Williams, GH; Williams, JS, 2006) |
"Aldosterone plays a crucial role in controlling mineral balance in our body." | 1.33 | Aldosterone-induced abnormal regulation of ENaC and SGK1 in Dahl salt-sensitive rat. ( Aoi, W; Marunaka, Y; Miyazaki, H; Niisato, N; Sawabe, Y, 2006) |
"A total of 25 patients with primary aldosteronism caused by Conn's adenoma, 29 patients with renovascular hypertension, and 29 patients with essential hypertension (EHT) were included in the present study." | 1.33 | Role of aldosterone in left ventricular hypertrophy in hypertension. ( Fujii, K; Iida, M; Matsumura, K; Oka, M; Oniki, H, 2006) |
"Primary aldosteronism is the most common form of mineralocorticoid hypertension." | 1.33 | [Diagnosis and treatment outcome in primary aldosteronism based on a retrospective analysis of 187 cases]. ( Dabasi, G; Füto, L; Gláz, E; Horányi, J; Jakab, C; Járay, J; Kiss, R; Major, L; Molnár, F; Patócs, A; Perner, F; Rácz, K; Szücs, N; Tóth, M; Tulassay, Z; Varga, I, 2006) |
"Resistant hypertension is common in clinical practice." | 1.33 | Aldosterone and refractory hypertension: a prospective cohort study. ( Calò, LA; Cattelan, F; Ciccariello, L; De Toni, R; Macchini, L; Mascagna, V; Pessina, AC; Realdi, A; Sartori, M; Semplicini, A, 2006) |
"Essential hypertension is associated with changes in central catecholaminergic pathways which might also be reflected in the pituitary response to stress stimuli." | 1.33 | Decreased pituitary response to insulin-induced hypoglycaemia in young lean male patients with essential hypertension. ( Cizmarova, E; Huckova, M; Koska, J; Kvetnansky, R; Penesova, A; Radikova, Z; Vigas, M, 2006) |
"Primary aldosteronism (PA) is the most frequent form of secondary hypertension, accounting for up to 5-10% of all hypertensive patients, and the diagnosis of PA can present an important challenge for the clinician." | 1.33 | Comparison of confirmatory tests for the diagnosis of primary aldosteronism. ( Fallo, F; Fardella, C; Maccario, M; Marafetti, L; Milan, A; Mosso, L; Mulatero, P; Pizzolo, F; Regolisti, G; Veglio, F, 2006) |
"Primary aldosteronism has recently been recognized as the most frequent cause of secondary hypertension." | 1.33 | Confirmatory testing in normokalaemic primary aldosteronism: the value of the saline infusion test and urinary aldosterone metabolites. ( Beuschlein, F; Maser-Gluth, C; Nickel, C; Reincke, M; Rüdiger, F; Schirpenbach, C; Seiler, L, 2006) |
"Aldosterone/salt-treated hypertensive rats exhibited severe proteinuria and renal injury characterized by glomerular sclerosis and tubulointerstitial fibrosis." | 1.33 | Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan. ( Abe, Y; Baba, R; Fan, YY; Fujita, M; Hosomi, N; Kimura, S; Kohno, M; Miyatake, A; Nagai, Y; Nishiyama, A; Sun, GP, 2006) |
"Patients with primary aldosteronism were compared with 247 patients with essential hypertension with the same severity and duration of disease and 102 normotensive subjects." | 1.33 | Insulin sensitivity in patients with primary aldosteronism: a follow-up study. ( Baroselli, S; Catena, C; Cavarape, A; Colussi, G; Favret, G; Lapenna, R; Melis, A; Nadalini, E; Novello, M; Sechi, LA, 2006) |
"Hypertension is rapidly reversible in the majority of heavy drinkers after the withdrawal of alcohol consumption." | 1.33 | Effects of alcohol withdrawal on blood pressure in hypertensive heavy drinkers. ( Basan, L; Casaccio, D; Donnini, D; Esposito, W; Isola, M; Milocco, C; Sechi, LA; Soardo, G; Soldano, F; Varutti, R, 2006) |
"To search for primary hyperaldosteronism (PHA) among previously known hypertensive patients in primary care, using the aldosterone/renin ratio (ARR), and to evaluate clinical and biochemical characteristics in patients with high or normal ratio." | 1.33 | High frequency of primary hyperaldosteronism among hypertensive patients from a primary care area in Sweden. ( Bergenfelz, A; Isaksson, A; Nerbrand, C; Valdemarsson, S; Westerdahl, C; Wihl, A, 2006) |
"Adenomatous primary aldosteronism (Conn's syndrome)." | 1.33 | Diagnosis of adenomatous primary aldosteronism in a patient with severe hypertension. ( Connell, JM; Freel, EM, 2005) |
"Indeed, obesity hypertension has to be considered as the most common form of essential hypertension." | 1.33 | Increased aldosterone/renin quotient in obese hypertensive women: a novel role for low-density lipoproteins? ( Ansurudeen, I; Bornstein, SR; Ehrhart-Bornstein, M; Kopprasch, S; Lamounier-Zepter, V; Rotthoff, T; Scherbaum, WA, 2006) |
"To screen primary aldosteronism cases with ARR (aldosterone/plasma renin activity, ARR) from patients with hypertension, and to evaluate the diagnosis value of ARR in primary aldosteronism cases and analysis the clinical characters of primary aldosteronism cases." | 1.33 | [Aldosterone/plasma renin activity ratio is a sensitive parameter for screening patients with primary aldosteronism]. ( Liu, ZJ; Shao, JM; Wang, DW; Yan, JT; Zhang, HL, 2006) |
"The clinical data of 267 patients of primary hyperaldosteronism with adrenal adenoma confirmed by operation 1995 - 2005 were analyzed." | 1.33 | [Causes of delaying diagnosis of primary hyperaldosteronism with adrenal adenoma and strategy therefore]. ( Li, HZ; Pan, DL; Yan, QZ, 2006) |
"Primary hyperparathyroidism was used first as a clinical model, in which hypercalcemia and normocalcemia occurs before and after surgery, respectively." | 1.32 | [Hormonal interactions of parathormone and calcium metabolism]. ( Kovács, L, 2003) |
"Liddle's syndrome is a monogenic form of hypertension caused by mutations in the PY motif of the COOH terminus of beta- and gamma-epithelial Na+ channel (ENaC) subunits." | 1.32 | Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin. ( Auberson, M; Hoffmann-Pochon, N; Kellenberger, S; Schild, L; Vandewalle, A, 2003) |
"The study was made in 45 patients with congestive heart failure treated in the Department of Cardiology." | 1.32 | [Cytokines and remodeling of the heart in patients with congestive heart failure]. ( Jołda-Mydłowska, B; Salomon, P, 2003) |
"Left ventricular hypertrophy was present in 60% of patients." | 1.32 | The role of biochemical tests and clinical symptoms in differential diagnosis of primary aldosteronism. ( Cybulska, I; Dobrucki, T; Janas, J; Janaszek-Sitkowska, H; Januszkiewicz, A; Kabat, M; Makowiecka-Cieśla, M; Peczkowska, M; Postuła, M; Prejbisz, A, 2003) |
"Overweight and obesity are frequently associated with increased plasma levels of aldosterone." | 1.32 | Human adipocytes secrete mineralocorticoid-releasing factors. ( Barthel, A; Bornstein, SR; Ehrhart-Bornstein, M; Hauner, H; Lamounier-Zepter, V; Langenbach, J; McCann, SM; Scherbaum, WA; Schraven, A; Willenberg, HS, 2003) |
"Aortic dissection is a rare but severe disease." | 1.32 | [Primary aldosteronism. A risk factor for aortic dissection?]. ( Blacher, J; Kesri, L; Mourad, JJ; Safar, M; Tartière, JM, 2003) |
"In glucocorticoid-remediable aldosteronism (GRA), there is a large interfamily variation of phenotype." | 1.32 | Coexistence of different phenotypes in a family with glucocorticoid-remediable aldosteronism. ( De Iasio, R; Fallo, F; Montanari, P; Morra Di Cella, S; Mulatero, P; Pilon, C; Sonino, N; Veglio, F; Williams, TA, 2004) |
"Increased bioavailability of reactive oxygen species (ROS) has been implicated in the pathogenesis of mineralocorticoid hypertension." | 1.32 | NAD(P)H oxidase inhibitor prevents blood pressure elevation and cardiovascular hypertrophy in aldosterone-infused rats. ( Park, JB; Park, MY; Park, YM; Suh, YL, 2004) |
"The severity of obstructive sleep apnea (OSA) correlates with the difficulty of controlling BP." | 1.32 | Aldosterone excretion among subjects with resistant hypertension and symptoms of sleep apnea. ( Calhoun, DA; Harding, SM; Nishizaka, MK; Zaman, MA, 2004) |
"Obstructive sleep apnea can be detected with a careful history and various sleep studies." | 1.32 | Resistant hypertension, obesity, sleep apnea, and aldosterone: theory and therapy. ( Calhoun, DA; Goodfriend, TL, 2004) |
"Primary aldosteronism (PA) is a common form of endocrine hypertension previously believed to account for less than 1% of hypertensive patients." | 1.32 | Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents. ( Fardella, CE; Gomez-Sanchez, CE; Gordon, RD; Loh, KC; Mosso, L; Mulatero, P; Stowasser, M; Veglio, F; Young, WF, 2004) |
"Once considered rare, primary aldosteronism (PAL) is now regarded as the commonest potentially curable and specifically treatable form of hypertension." | 1.32 | Primary aldosteronism--careful investigation is essential and rewarding. ( Gordon, RD; Stowasser, M, 2004) |
"Hyperaldosteronism was diagnosed on the basis of a renin activity <1." | 1.32 | Impaired endothelium-dependent flow-mediated vasodilation in hypertensive subjects with hyperaldosteronism. ( Calhoun, DA; Green, SA; Nishizaka, MK; Renfroe, KY; Zaman, MA, 2004) |
"Primary hyperaldosteronism was not detected among the normokalemic essential hypertensives at any age using aldosterone/plasma renin activity ratio as a primary screening method." | 1.32 | Age dependence of the levels of plasma norepinephrine, aldosterone, renin activity and urinary vanillylmandelic acid in normal and essential hypertensives. ( Abd-Allah, NM; Esmat, AY; Hammad, SA; Hassan, FH, 2004) |
"Primary hyperaldosteronism is a well-recognized cause of secondary hypertension." | 1.32 | Serum aldosterone and the incidence of hypertension in nonhypertensive persons. ( Benjamin, EJ; Evans, JC; Larson, MG; Levy, D; Meigs, JB; Rifai, N; Vasan, RS; Wilson, PW, 2004) |
"Overweight and obesity are frequently associated with increased plasma levels of aldosterone suggesting a direct link between obesity hypertension and increased mineralocorticoid levels." | 1.32 | Fat cells may be the obesity-hypertension link: human adipogenic factors stimulate aldosterone secretion from adrenocortical cells. ( Arakelyan, K; Bornstein, SR; Ehrhart-Bornstein, M; Krug, AW; Scherbaum, WA, 2004) |
"Primary aldosteronism (PA) is characterized by hypertension and suppressed renin activity with or without hypokalemia and comprises the aldosterone-producing adenoma (APA) and bilateral adrenal hyperplasia or idiopatic hyperaldosteronism (IHA)." | 1.32 | The syndromes of low-renin hypertension: "separating the wheat from the chaff". ( Biglieri, EG; Kater, CE, 2004) |
"In patients with untreated hypertension, there is evidence of increased collagen synthesis, degradation, and inhibition of degradation resulting in fibrosis." | 1.31 | TIMP-1: a marker of left ventricular diastolic dysfunction and fibrosis in hypertension. ( Dunn, FG; Lindsay, MM; Maxwell, P, 2002) |
"In patients with primary aldosteronism treated with spironolactone (n = 8), renin escaped suppression and reached very high levels." | 1.31 | Influence of antihypertensive medication on aldosterone and renin concentration in the differential diagnosis of essential hypertension and primary aldosteronism. ( Hahn, EG; Hensen, J; Schobel, H; Seifarth, C; Trenkel, S, 2002) |
"The prevalence of primary aldosteronism (PA) was assessed in a specialized hypertension center." | 1.31 | High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives. ( Davoli, S; Negro, A; Perazzoli, F; Regolisti, G; Rossi, E; Sani, C, 2002) |
"Thus aldosterone and salt treatment in uninephrectomized rats led to severe hypertension and the development of a vascular inflammatory phenotype in the heart, which may represent one mechanism by which aldosterone contributes to myocardial disease." | 1.31 | Aldosterone induces a vascular inflammatory phenotype in the rat heart. ( Blomme, EA; Delyani, JA; Frierdich, GE; Kekec, BK; McMahon, EG; Nachowiak, DA; Rocha, R; Rudolph, AE, 2002) |
"Aldosterone excretion was also lower in blacks and without its normal circadian pattern which may, in part, explain their altered potassium excretion pattern." | 1.31 | Racial differences in response to acute dosing with hydrochlorothiazide. ( King, K; Ripley, E; Sica, DA, 2000) |
"Hyperaldosteronism sustains much of the hypertension, but the stimuli to the increased aldosterone levels are uncertain." | 1.31 | Role of dietary potassium in the hyperaldosteronism and hypertension of the remnant kidney model. ( Hostetter, TH; Ibrahim, HN, 2000) |
"Primary aldosteronism (PA) was thought to be rare but recent evidence from Australia suggests that it may be more common." | 1.31 | High prevalence of primary aldosteronism in the Tayside hypertension clinic population. ( Brennan, G; Dow, E; Jung, RT; Lim, PO; MacDonald, TM, 2000) |
"A Fludrocortisone test was done to confirm the diagnosis." | 1.31 | Primary hyperaldosteronism in essential hypertensives: prevalence, biochemical profile, and molecular biology. ( Cortés, P; Fardella, CE; Foradori, A; Gómez, L; Gómez-Sánchez, C; Huete, A; Montero, J; Mosso, L; Oestreicher, E; Pinto, M; Soto, J, 2000) |
"Aldosterone was unresponsive (rose by <50%) to AII in all subjects." | 1.31 | Severity of hypertension in familial hyperaldosteronism type I: relationship to gender and degree of biochemical disturbance. ( Bachmann, AW; Gordon, RD; Huggard, PR; Rossetti, TR; Stowasser, M, 2000) |
"Primary aldosteronism was confirmed with the determination of PAC after 2 L saline administered iv over 4 h." | 1.31 | Prevalence of primary aldosteronism among Asian hypertensive patients in Singapore. ( Emmanuel, SC; Khaw, MC; Koay, ES; Loh, KC; Young, WF, 2000) |
"Spironolactone prevented cardiac hypertrophy in adrenalectomized SHRSP." | 1.31 | Cardiac aldosterone production in genetically hypertensive rats. ( Demura, M; Mabuchi, H; Miyamori, I; Takeda, Y; Yoneda, T, 2000) |
"An early diagnosis and treatment of AME syndrome could help to prevent these sequelae, and to preserve renal function." | 1.31 | Nephrocalcinosis and renal cysts associated with apparent mineralocorticoid excess syndrome. ( Jordan, SC; Kamil, ES; Moudgil, A; Rodich, G, 2000) |
"A rat model of intrauterine growth retardation was employed." | 1.31 | Prenatal programming of adult hypertension in the rat. ( Aviles, DH; Manning, J; Vehaskari, VM, 2001) |
"To measure the effects of hyperinsulinemia on serum electrolyte status and associated hormones, and on serum free fatty acid (FFA) concentrations, in patients with essential hypertension." | 1.31 | Serum aldosterone changes during hyperinsulinemia are correlated to body mass index and insulin sensitivity in patients with essential hypertension. ( Haenni, A; Lind, L; Lithell, H; Reneland, R, 2001) |
"Gestational hypertension is a multisystem disorder which always resolves itself after delivery; its primary pathology still remains incompletely clarified." | 1.31 | The renin-aldosterone system during normal and hypertensive pregnancy. ( Creatsas, G; Elsheikh, A; Loutradis, D; Mastorakos, G; Michalas, S; Milingos, S, 2001) |
"Liddle's syndrome is a rare form of hereditary hypertension caused by mutations of the epithelial sodium (Na(+)) channel (ENaC)." | 1.31 | Two sporadic cases of Liddle's syndrome caused by De novo ENaC mutations. ( Dohi, K; Enomoto, N; Hashimoto, K; Koga, M; Marumo, F; Sasaki, S; Takeda, Y; Uchida, S; Yamano, S; Yamashita, Y, 2001) |
"The traditional workup for primary aldosteronism is cumbersome and requires discontinuing antihypertensive medications, which is inconvenient and potentially dangerous." | 1.31 | Screening for primary aldosteronism without discontinuing hypertensive medications: plasma aldosterone-renin ratio. ( Ahmad, S; Davidson, RC; Gallay, BJ; Toivola, B; Xu, L, 2001) |
"Specific treatment of primary aldosteronism (adrenalectomy, treatment with spironolactone) led to the normalization of the BP curve with a marked BP decline." | 1.31 | Twenty-Four hour blood pressure profile in subjects with different subtypes of primary aldosteronism. ( Widimský, J; Zelinka, T, 2001) |
"Primary hyperaldosteronism is more frequent among subjects with essential hypertension than previously thought." | 1.31 | [Excess of mineralocorticoids in essential hypertension: clinical-diagnostic approach]. ( Ahuad, J; Claverie, X; Cortés, P; Fardella, C; Foradori, A; Gac, H; Montero, J; Mosso, L; Oestreicher, E; Soto, J, 2000) |
"Amlodipine treatment reduced the level of adrenocortical angiotensin II type 2 receptor (AT2R) mRNA in SHR from 8 weeks of age." | 1.31 | Chronic treatment with amlodipine modulates adrenocortical angiotensin II receptors in spontaneously hypertensive rats. ( Kataoka, H; Kishida, M; Makino, H; Mimura, Y; Nakamura, Y; Ogura, T; Otsuka, F; Takahashi, M; Yamauchi, T; Yokota, K, 2001) |
"Liddle's syndrome is a rare form of autosomal-dominant salt-sensitive hypertension." | 1.31 | A family with liddle's syndrome caused by a mutation in the beta subunit of the epithelial sodium channel. ( Kitamura, K; Kyuma, M; Sasaki, S; Shimamoto, K; Takeuchi, H; Takizawa, H; Tomita, K; Torii, T; Ura, N, 2001) |
"Hypertension was resolved at follow-up (blood pressure < 140/90 mm Hg) without use of antihypertensive agents in 31 of 93 patients (33%)." | 1.31 | Primary aldosteronism: factors associated with normalization of blood pressure after surgery. ( Farley, DR; Grant, CS; Leibson, C; Sawka, AM; Thompson, GB; van Heerden, JA; Young, WF, 2001) |
"Malignant hypertension is a serious form of arterial hypertension in which the physiopathological mechanisms include increased activity of the sympathetic nervous system, renin angiotensin system, and endothelium dysfunction." | 1.31 | Hemodynamic and metabolic profile in offspring of malignant hypertensive parents. ( Bortolotto, LA; Kamitsuji, CS; Krieger, EM; Lopes, HF; Szlejf, C, 2001) |
"Enrasentan-treated groups exhibited significantly improved survival (90-95% vs." | 1.31 | Enrasentan improves survival, limits left ventricular remodeling, and preserves myocardial performance in hypertensive cardiac hypertrophy and dysfunction. ( Aiyar, N; Anderson, KM; Barone, FC; Coatney, RW; Nelson, AH; Ohlstein, EH; Olzinski, AR; Willette, RN; Woods, T, 2001) |
"Primary aldosteronism is a common cause of non-renal secondary hypertension." | 1.31 | Normokalemic hyperaldosteronism in patients with resistant hypertension. ( Benchetrit, S; Bernheim, J; Podjarny, E, 2002) |
" Losartan improved the shifted circadian BP rhythm towards the active phase in a dose-dependent manner, whereas the improvement caused by 1 and 3 mg/day of benazepril was less effective than the same dosage of losartan." | 1.31 | Effects of losartan and benazepril on abnormal circadian blood pressure rhythm and target organ damage in SHRSP. ( Hayasaki-Kajiwara, Y; Iwasaki, T; Nakajima, M; Naya, N; Shimamura, T, 2002) |
"1." | 1.31 | Is primary aldosteronism underdiagnosed in clinical practice? ( Bobrie, G; Fiquet-Kempf, B; Launay-Mignot, P; Plouin, PF, 2001) |
"Since primary aldosteronism has been reported in asymptomatic incidental adrenal masses (adrenal incidentalomas, AI), the aim of our study was to detect primary aldosteronism in normokalemic patients with AI and to verify whether a raised plasma aldosterone (ALD)/plasma renin activity (PRA) ratio may be useful for diagnosis." | 1.31 | Primary aldosteronism in normokalemic patients with adrenal incidentalomas. ( Argenio, G; Bernini, G; Moretti, A; Salvetti, A, 2002) |
"In 92 patients with chronically treated essential hypertension, two-dimensional and Doppler echocardiographic examinations were performed and LV inflow velocities were measured for evaluation of LV diastolic function." | 1.31 | Influence of plasma aldosterone on left ventricular geometry and diastolic function in treated essential hypertension. ( Horio, T; Iwashima, Y; Kawano, Y; Kuroda, S; Takishita, S, 2002) |
"Also, 17 patients with known primary aldosteronism were retrospectively examined." | 1.31 | Ratio of serum aldosterone to plasma renin concentration in essential hypertension and primary aldosteronism. ( Hahn, EG; Hensen, J; Schobel, H; Seifarth, C; Trenkel, S, 2002) |
"Aldosterone levels were significantly reduced by all treatments." | 1.31 | Combination of non-hypotensive doses of valsartan and enalapril improves survival of spontaneously hypertensive rats with endothelial dysfunction. ( Bruneval, P; Clozel, JP; de Gasparo, M; Hess, P; Nuesslein-Hildesheim, B, 2000) |
"Primary aldosteronism is a disorder that is commonly considered in patients referred to the hypertension clinic." | 1.31 | Unilateral adrenal hyperplasia causing primary aldosteronism: limitations of I-131 norcholesterol scanning. ( Arici, MH; Karimeddini, MK; Malchoff, CD; Mansoor, GA; Whalen, GF, 2002) |
"Since hypertension affects a considerable proportion of obese patients, circulating RAAS has been studied in obese subjects with and without hypertension, albeit with conflicting results." | 1.31 | Comparison of circulating and local adipose tissue renin-angiotensin system in normotensive and hypertensive obese subjects. ( Camilloni, MA; Faloia, E; Garrapa, GG; Gatti, C; Giacchetti, G; Mantero, F; Mariniello, B; Sardu, C, 2002) |
"Hyperaldosteronism has been causally linked to myocardial interstitial fibrosis experimentally, but it remains unclear if this link also applies to humans." | 1.31 | Excess aldosterone is associated with alterations of myocardial texture in primary aldosteronism. ( Bertini, A; Cesari, M; Di Bello, V; Ganzaroli, C; Giorgi, D; Mariani, M; Pessina, AC; Rossi, GP; Sacchetto, A; Scognamiglio, R, 2002) |
"The triamterene therapy was effective in correcting the endocrine and metabolic disorders as well as arterial hypertension, but did not prevent a deficit in mental and physical development." | 1.30 | Liddle's syndrome: a 14-year follow-up of the youngest diagnosed case. ( Capodaglio, PF; Cugini, P; Mazzeo, D; Tucciarone, L; Vania, A, 1997) |
"Men with left ventricular hypertrophy presented with significantly higher serum ACE concentrations than those with normal left ventricular mass index (P = 0." | 1.30 | Associations between circulating components of the renin-angiotensin-aldosterone system and left ventricular mass. ( Danser, AH; Hense, HW; Kürzinger, S; Luchner, A; Muscholl, M; Riegger, GA; Schunkert, H, 1997) |
"In primary aldosteronism, protein kinase C and calmodulin seem to have synergistic stimulatory effects on red blood cell Na(+)-H+ exchange, and both increase the affinity of the exchanger to H+, while their effect on Na+ binding is opposite." | 1.30 | Increased Na(+)-H+ exchange in red blood cells of patients with primary aldosteronism. ( Koren, W; Postnov, IY; Postnov, YV, 1997) |
"In contrast, left ventricular hypertrophy markedly progressed despite the mild extracardiac target-organ damage in primary aldosteronism." | 1.30 | Left ventricular hypertrophy precedes other target-organ damage in primary aldosteronism. ( Hamada, M; Hara, Y; Hayashi, Y; Hiwada, K; Kodama, K; Kohara, K; Okayama, H; Shigematsu, Y, 1997) |
"Aldosterone treatment of vascular smooth muscle cells cultured from WF resulted in 82% less upregulation of angiotensin II radioligand binding, 50% less induction of angiotensin II AT1a receptor mRNA, and 76% less potentiation of angiotensin II-stimulated inositol phosphates than did aldosterone treatment of cells from W." | 1.30 | Resistance to mineralocorticoids in Wistar-Furth rats. ( Fitzgibbon, WR; Islam, MM; Paul, RV; Robinson, CJ; Tobin, ET; Ullian, ME, 1997) |
"Liddle's syndrome is an autosomal dominant form of hypertension that resembles primary hyperaldosteronism, is characterized by the early onset of hypertension with hypokalemia and suppression of both PRA and aldosterone, and is caused by mutations in the carboxyl-terminus of the beta- or gamma-subunits of the renal epithelial sodium channel." | 1.30 | Liddle's syndrome: prospective genetic screening and suppressed aldosterone secretion in an extended kindred. ( Findling, JW; Hansson, JH; Lifton, RP; Raff, H, 1997) |
"Since hyperaldosteronism has been experimentally related to myocardial interstitial fibrosis, we investigated the effects of hypertension and excess aldosterone due to aldosterone-producing adenomas (APAs) on the heart." | 1.30 | Remodeling of the left ventricle in primary aldosteronism due to Conn's adenoma. ( Canali, C; Graniero, GR; Palatini, P; Pavan, E; Pessina, AC; Rossi, GP; Sacchetto, A, 1997) |
"A case of primary hyperaldosteronism and cardiomegaly due to a unilateral adrenal adenoma in a newborn is presented." | 1.30 | Hypertensive cardiomegaly caused by an aldosterone-secreting adenoma in a newborn. ( Armanini, D; Cecchetto, G; Fassina, A; Opocher, G; Pozzan, GB; Rigon, F; Zacchello, F, 1997) |
"The results suggest that left ventricular hypertrophy is more pronounced in patients with primary aldosteronism than in patients with other forms of hypertension." | 1.30 | Left ventricular hypertrophy is more prominent in patients with primary aldosteronism than in patients with other types of secondary hypertension. ( Demura, H; Demura, R; Hase, M; Naruse, K; Naruse, M; Seki, T; Tanabe, A; Tanaka, M; Yoshimoto, T, 1997) |
"We evaluated the renal hemodynamic status of 19 hypertensive patients with NIDDM under controlled sodium balance, low (10 mmol/day for 5 to 7 days) or high (200 mmol/day for 5 to 7 days)." | 1.30 | Autonomy of the renin system in type II diabetes mellitus: dietary sodium and renal hemodynamic responses to ACE inhibition. ( Allan, DR; De'Oliveira, JM; Fisher, ND; Hollenberg, NK; McKnight, JA; Price, DA; Williams, GH, 1997) |
"Glucocorticoid-remediable aldosteronism (GRA) is a rare form of inherited hypertension caused by a characteristic gene duplication." | 1.30 | Evaluation of the dexamethasone suppression test for the diagnosis of glucocorticoid-remediable aldosteronism. ( Coolidge, C; Dluhy, RG; Lifton, RP; Litchfield, WR; New, MI, 1997) |
"The syndrome is characterised by sodium retention and hypervolemia despite low plasma renin activity and aldosterone levels." | 1.30 | [A case of apparent mineralocorticoid excess caused by type 2 11 beta- hydroxysteroid dehydrogenase deficiency]. ( Caillette, A; Corvol, P; Fiet, J; Krozowski, Z; Marc, JM; Morineau, G; Pascoe, L, 1997) |
" A dose-response curve to acetylcholine was performed at cumulative concentrations from 10(-9) to 10(-5) mol/L." | 1.30 | Endothelial dysfunction in hypertension is independent from the etiology and from vascular structure. ( Agabiti-Rosei, E; Bernini, G; Bettoni, G; Castellano, M; Giulini, SM; Muiesan, ML; Porteri, E; Rizzoni, D; Rossi, G; Tiberio, G, 1998) |
"L-NAME treatment induced hypertension that was associated with increased plasma renin activity." | 1.30 | Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo. ( Brosnan, MJ; Devlin, AM; Dominiczak, AF; Graham, D; Hamilton, CA; McIntyre, M; McPhaden, AR; Morton, JJ; Reid, JL, 1998) |
"Aldosterone levels during treatment [13." | 1.30 | Evidence for persistent dysfunction of wild-type aldosterone synthase gene in glucocorticoid-treated familial hyperaldosteronism type I. ( Gartside, MG; Gordon, RD; Stowasser, M; Taylor, WL; Tunny, TJ, 1997) |
"RFR was examined in 33 IDDM patients in similar glycaemic and metabolic control and compared to 12 healthy control subjects, during eight 1 h clearance periods prior to, during and after a 3-h stimulation by amino acid infusion (4." | 1.30 | Renal functional reserve in IDDM patients. ( Ader, JL; Hanaire-Broutin, H; Sackmann, H; Tack, I; Tauber, JP; Tran-Van, T, 1998) |
"Hypertension is a common multifactorial disorder associated with considerable morbidity and mortality." | 1.30 | The diagnosis of Liddle syndrome by identification of a mutation in the beta subunit of the epithelial sodium channel. ( Houtman, P; Jackson, SN; Trembath, RC; Williams, B, 1998) |
"In conclusion, primary aldosteronism is characterized by decreased supine and standing BP variability, which is due in part to the preservation of baroreflex function." | 1.30 | Decreased blood pressure variability at rest in patients with primary aldosteronism. ( Abe, K; Aihara, A; Imai, Y; Munakata, M; Yoshinaga, K, 1998) |
"As insulin resistance has been suggested as the unifying factor in the insulin resistance metabolic syndrome, insulin resistance was evaluated by the euglycaemic hyperinsulinaemic clamp technique in 50 untreated hypertensive subjects in whom PRA and serum aldosterone were measured together with lipids and an intravenous glucose tolerance test (IVGTT)." | 1.30 | Insulin resistance in essential hypertension is related to plasma renin activity. ( Andersson, PE; Haenni, A; Lind, L; Lithell, H; Reneland, R, 1998) |
"Aldosterone-salt treatment induced, (1) arterial hypertension (+40%) and LV hypertrophy (+60%) without altering LV-fractional shortening, (2) an increase in plasma norepinephrine levels (+262%) and suppression of renin activity." | 1.30 | Modifications of myocardial Na+,K(+)-ATPase isoforms and Na+/Ca2+ exchanger in aldosterone/salt-induced hypertension in guinea pigs. ( Carayon, A; Charlemagne, D; Lechat, P; Mougenot, N; Ramírez-Gil, JF; Trouvé, P, 1998) |
"Cardiac fibrosis is linked to aldosterone-induced hypertension, but the effects on in vivo left ventricular (LV) function are not established." | 1.30 | In vivo left ventricular function and collagen expression in aldosterone/salt-induced hypertension. ( Charlemagne, D; Delcayre, C; Lechat, P; Mougenot, N; Ramirez-Gil, JF; Robert, V; Trouve, P; Wassef, M, 1998) |
"Twenty-three patients with primary aldosteronism, 22 essential hypertensive patients and 16 normal controls were studied." | 1.30 | Impaired baroreflex function and arterial compliance in primary aldosteronism. ( Cat Genova, G; Chiandussi, L; Grosso, T; Martini, G; Melchio, R; Molino, P; Rabbia, F; Veglio, F, 1999) |
"Low-renin hypertension is characterized by a high ratio of aldosterone to plasma renin activity (ALD/PRA), which may suggest inappropriately increased aldosterone biosynthesis." | 1.30 | Genetic polymorphism of CYP11B2 gene and hypertension in Japanese. ( Iwai, N; Kinoshita, M; Tamaki, S; Tsujita, Y, 1999) |
"Because essential hypertension is partly genetic, it is possible that altered control of aldosterone synthase gene expression or translation may be responsible." | 1.30 | Aldosterone excretion rate and blood pressure in essential hypertension are related to polymorphic differences in the aldosterone synthase gene CYP11B2. ( Anderson, NH; Connell, JM; Davies, E; Fraser, R; Friel, EC; Holloway, CD; Inglis, GC; Ingram, MC; Morrison, C, 1999) |
"Patients with newly discovered, never-treated, sustained hypertension were included in the study after a 1 month run-in, during which time their blood pressure was measured three times at 2 week intervals." | 1.30 | Clinic-daytime blood pressure difference and cardiovascular damage. ( Celentano, A; Crivaro, M; Ferrara, LA; Gaeta, I; Guida, L; Iannuzzi, R; Marotta, T; Pasanisi, F, 1999) |
"Normotensive primary hyperaldosteronism is exceedingly rare." | 1.30 | Aldosterone-producing adenoma without hypertension: a report of two cases. ( Ghulam, A; Jeunemaitre, X; Lefebvre, J; Provost, F; Ronci, N; Tabarin, A; Vantyghem, MC, 1999) |
"To study severity of left ventricular hypertrophy (LVH) and left ventricular function in patients with primary aldosteronism (PA) in comparison with hyperaldosteronemia and preoperative arterial hypertension, to follow the dynamics of these parameters early and late after surgical removal of aldosteroma." | 1.30 | [Left ventricular myocardial structure and function in patients with primary aldosteronism]. ( Arabidze, GG; Chikhladze, NM; Iarovaia, EB; Sergakova, LM, 1999) |
"Treatment with amiloride was effective." | 1.30 | [Mineralocorticoid-like hypertension. "Apparent mineralocorticoid excess". A hereditary type of hypertension?]. ( Christensen, TH; Ibsen, H; Kaae, HH, 1999) |
"Neurofibromatosis type 1 is a phacomatosis." | 1.30 | A case of neurofibromatosis type 1 with an aldosterone-producing adenoma of the adrenal. ( Alessandri, M; Biagi, P; Campanella, G; Castro, R; Fanciullacci, M; Totteri, A, 1999) |
"Animal models for preeclampsia are no alternative to clinical studies, but they are furthering our understanding of pathophysiology in many fields." | 1.30 | [Animal experiment models of hypertension in pregnancy--an alternative to clinical studies?]. ( Casper, F; Hropot, M; Leiser, R; Seufert, R, 1999) |
"Primary hyperaldosteronism is more frequent than previously thought, it is overlooked when hypokalemia is used as the screening test and it can only be diagnosed measuring plasma aldosterone and renin activity." | 1.30 | [High prevalence of undiagnosed primary hyperaldosteronism among patients with essential hypertension]. ( Fardella, C; Foradori, A; Huete, A; Montero, J; Mosso, L; Rojas, A; Rojas, P; Rojas, V; Sánchez, O; Soto, J, 1999) |
"Aldosterone-renin ratio was in PH patients 10-fold higher comparing with EH patients." | 1.30 | [Incidence of primary hyperaldosteronism in hospitalized patients with hypertension]. ( Bober, J; Lazurova, I; Schwartz, P; Sokol, L; Trejbal, D; Trejbalova, L; Valansky, L; Wagnerova, H; Zachar, M, 1999) |
"Primary aldosteronism comprises two different conditions, the tumoral form usually caused by an adenoma and the idiopathic form due to nodular hyperplasia of the two adenals." | 1.29 | [Conceptual basis and diagnosis of primary hyperaldosteronism]. ( Amar, J; Begasse, F; Chamontin, B; Guittard, J; Salvador, M, 1995) |
"Dexamethasone-sensitive hyperaldosteronism is associated with early onset hypertension and primary hyperaldosteronism." | 1.29 | [Hyperaldosteronism sensitive to dexamethasone with adrenal adenoma. Clinical, biological and genetic study]. ( Aupetit-Faisant, B; Charru, A; Corvol, P; Guyene, TT; Jeunemaitre, X; Pascoe, L; Plouin, PF; Schambelan, M; Shackleton, CH, 1995) |
" Co-administration with propranolol markedly decreased the heart rate, but little affected the heart weight, suggesting changes in the heart rate during the long-term administration of KW-3049 did not largely affect cardiac hypertrophy." | 1.29 | Effect of the new calcium antagonist (+/-)-(R*)-3-[(R*)-1-benzyl-3- piperidyl] methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5- pyridinedicarboxylate hydrochloride (KW-3049) on cardiac hypertrophy in spontaneously hypertensive rats. ( Deguchi, T; Hara, T; Hattori, O; Kato, Y; Saijyo, T; Suzuki, K; Tanaka, H, 1993) |
" In summary, during long-term administration of L-NAME, progressive increases in BP levels were observed without changes in either sodium excretion or enhanced circulating vasoconstrictor activity." | 1.29 | Hormonal, renal, and metabolic alterations during hypertension induced by chronic inhibition of NO in rats. ( García-Estań, J; Lahera, V; Moncada, S; Navarro, J; Romero, JC; Ruilope, LM; Sáiz, J; Sanchez, A, 1994) |
"The degree of hyperaldosteronism in the subjects was mild compared with other conditions and, although an effect on left ventricular mass index could be detected, the present results indicate that other factors may be necessary for the development of left ventricular hypertrophy." | 1.29 | Left ventricular mass in hereditary human hypertension: glucocorticoid-suppressible hyperaldosteronism. ( Connell, JM; Jamieson, A; Kennedy, JA; Murdoch, D, 1995) |
"Preeclampsia is accompanied by amplification of the sodium retention that is a feature of normal pregnancy." | 1.29 | 11 beta-Hydroxysteroid dehydrogenase and its inhibitors in hypertensive pregnancy. ( Brown, MA; Edwards, CR; Honour, JW; Walker, BR; Whitworth, JA; Williamson, PM, 1995) |
"Nephrocalcinosis was still present 8 years later and hypertension was recurring obviously as a consequence of increased peripheral resistance." | 1.29 | Aldosterone and testosterone producing adrenal adenoma in childhood. ( Burda, G; Frisch, H; Neuhold, N; Schmitt, K; Schober, E, 1995) |
"01) with chronic administration of propranolol, suggesting a reflection of decreased cardiac function." | 1.29 | Atrial natriuretic peptide and antihypertensive action due to beta-blockade in essential hypertensive patients. ( Hama, J; Horiuchi, M; Kamoi, K; Katori, R; Kino, H; Nagata, S; Shimada, S; Takenaka, T, 1995) |
"In patients with primary aldosteronism and renovascular hypertension the plasma aldosterone level was shown to be an important factor upregulating AT1 receptor mRNA." | 1.29 | Angiotensin II type 1 receptor messenger RNA levels in human blood cells of patients with primary and secondary hypertension: reference to renin profile. ( Murakami, M; Saruta, T; Sato, A; Shibata, H; Suzuki, H, 1994) |
"Primary aldosteronism caused by an aldosterone-producing adrenal adenoma was documented in an 11-year-old girl who presented with persistent hypertension, headache, tinnitus and hypokalemia." | 1.29 | Adrenal adenoma with primary aldosteronism in a child: a case report. ( Chang, WT; Chen, HC; Lai, FC; Peng, HC; Wen, MC, 1994) |
"Spironolactone treatment (50 mg/kg per day) for 7 days in deficient rats restored blood pressure and heart rate to normal levels and significantly reduced sodium levels in erythrocytes and cerebrospinal fluid." | 1.29 | Hypertension induced by a nonpressor dose of angiotensin II in kininogen-deficient rats. ( Katori, M; Kuribayashi, Y; Majima, M; Mizogami, S; Oh-ishi, S, 1994) |
"Arterial hypertension is nowadays no longer considered an isolated disorder of blood pressure regulation but a multifactorial disease with metabolic and cellular deviations." | 1.29 | [Changes in humoral pressor and depressor factors in essential hypertension during lisinopril therapy]. ( Horký, K; Jáchymová, M; Jarolím, M; Jindra, A; Kolár, J; Peleska, J; Savlíková, J; Stolba, P; Umnerová, V; Vorlová, Z, 1994) |
"Spironolactone treatment (100 mg/daily) completely reversed the syndrome of mineralocorticoid excess." | 1.29 | Unilateral adrenal hypersecretion of both aldosterone and cortisol in two first cousins with a syndrome of mineralocorticoid excess but without signs of hypercortisolism. ( Balsano, F; Bonavita, MS; Carlomagno, A; Coassin, S; De Siati, L; Falaschi, P; Ferri, C; Gualdi, G, 1994) |
" The hypotensive action of NZ-105 were reproducible after repeated dosing for 12 weeks." | 1.29 | Effects of long-term oral administration of NZ-105, a novel calcium antagonist, with or without propranolol in spontaneously hypertensive rats. ( Kasuya, Y; Masuda, Y; Sakai, T; Shigenobu, K; Shudo, C; Tanaka, S, 1993) |
"1." | 1.29 | Acute sodium loading in patients with uncomplicated diabetes mellitus: renal and hormonal effects. ( Beretta-Piccoli, C; Cusi, D; Elshater-Zanetti, F; Shaw, S; Weidmann, P, 1994) |
"From these data it emerges that hyperaldosteronism, as observed in these patients with CRI, is a relatively reliable marker of the extent of CRI and may occur independently of the activation of the RAA system, given that other factors, such as orthostatic stimulation, alterations in the acid-base equilibrium, and the degree of aldosterone hepatic and urinary clearance, contribute to its pathogenesis." | 1.29 | [Role of aldosterone in essential arterial hypertension complicated by chronic renal insufficiency]. ( Buracchi, P; Carletti, F; Gennari, C; Lucani, B; Martinelli, M; Nami, R; Panza, F; Pavese, G; Saia, F, 1993) |
"The hyperaldosteronism could not be suppressed by dexamethasone." | 1.29 | [Unilateral autonomous aldosterone production in hyperaldosteronism suppressible by dexamethasone]. ( Haack, D; Jakob, F; Ludwig, J; Rendl, J; Schröder, K; Seufert, J; Vecsei, P, 1993) |
"The reactive fibrosis is thought to be related to MC excess, while cell loss and microscopic scarring may be secondary to enhanced potassium excretion or a cytotoxic effect of aldosterone." | 1.29 | Myocardial fibrosis in the rat with mineralocorticoid excess. Prevention of scarring by amiloride. ( Campbell, SE; Janicki, JS; Matsubara, BB; Weber, KT, 1993) |
"Effective management of primary aldosteronism is dependent upon correct localization of excessive aldosterone production." | 1.29 | Evaluation of diagnostic tests in the differential diagnosis of primary aldosteronism: unilateral adenoma versus bilateral micronodular hyperplasia. ( Bihrle, R; Donohue, JP; Dugan, J; Eller, D; Gleason, PE; Pratt, JH; Weinberger, MH, 1993) |
"Spironolactone, however, was able to prevent myocardial fibrosis in RHT and aldosterone models of acquired arterial hypertension irrespective of the development of LVH and the presence of hypertension." | 1.29 | Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension. ( Brilla, CG; Matsubara, LS; Weber, KT, 1993) |
"As our model we selected type 1 diabetes with peripheral circulatory hyperinsulinemia induced by sc insulin treatment." | 1.29 | Nocturnal blood pressure elevation is related to adrenomedullary hyperactivity, but not to hyperinsulinemia, in nonobese normoalbuminuric type 1 diabetes. ( Gromeier, S; Kerner, W; Kohlmann, T; Look, D; Peters, A, 1996) |
"Primary aldosteronism (PA) is caused by an adrenal aldosterone-producing tumor (A-APT) or adrenal hyperplasia." | 1.29 | Prevalence of adrenal and extra-adrenal Conn syndrome in hypertensive patients. ( Abdelhamid, S; Bönhof, JA; Müller-Lobeck, H; Pahl, S; Remberger, K; Röckel, A; Walb, D, 1996) |
"Although primary hyperaldosteronism is an uncommon cause of hypertension, it is the most common form of renin-independent hypermineralocorticoidism." | 1.29 | [Adrenal adenoma or hyperplasia? Problems of differential diagnosis in an unusual case of primary hyperaldosteronism]. ( Bonifacio, V; Ciampani, T; Giannini, D; Mancini, G; Sanna, AL, 1996) |
"It has been recognised recently that primary hyperaldosteronism may be more common than previously thought, the frequency of diagnosis being improved by screening using a plasma aldosterone concentration to renin activity ratio." | 1.29 | Primary hyperaldosteronism: a missed diagnosis in 'essential hypertensives'? ( Brown, MA; Cramp, HA; Whitworth, JA; Zammit, VC, 1996) |
"Aldosterone was unresponsive (<50% rise) to 2 h of upright posture following overnight recumbency in 15 out of 15 (100%) patients studied, and to angiotensin II infusion (2 ng/kg per min for 1 h) in 14 out of 14 patients (100%)." | 1.29 | Clinical, biochemical and genetic approaches to the detection of familial hyperaldosteronism type I. ( Bachmann, AW; Gordon, RD; Jonsson, JR; Klemm, SA; Stowasser, M; Tunny, TJ, 1995) |
"The patients with primary aldosteronism had lower serum potassium and higher plasma aldosterone concentrations than those with essential hypertension." | 1.29 | Albuminuria in untreated patients with primary aldosteronism or essential hypertension. ( Halimi, JM; Mimran, A, 1995) |
"In control subjects and patients with Conn's syndrome, the DOC:B ratio was not affected by ACTH." | 1.29 | 11 beta-Hydroxylase activity in glucocorticoid suppressible hyperaldosteronism: lessons for essential hypertension? ( Connell, JM; Davies, E; Fraser, R; Ingram, M; Jamieson, AJ; Soro, A, 1996) |
"Nilvadipine appears to be an effective hypotensive agent at single daily doses of 8 mg." | 1.28 | Nilvadipine in hypertension with renal dysfunction. ( Albert, FW; Berger, HH, 1992) |
"Liddle's syndrome (or pseudoprimary aldosteronism) is a rare hereditary disease; only 18 cases have been reported since 1963." | 1.28 | [Liddle syndrome (or pseudo-hyperaldosteronism). Long-term development and erythrocyte potassium flow study in 4 cases]. ( Charpentier, B; Dommergues, JP; Fries, D; Garay, RP; Guillot, M; Jullien, M; Kleinknecht, D; Nazaret, C; Noblins, M, 1992) |
"ANP, aldosterone and renin were examined during natriuresis of fasting in 25 obese essential hypertensive patients and nine overweight normotensive subjects placed on a supervised 500-KCal diet composed of 50% carbohydrates, 30% fat and 20% protein, and unlimited salt." | 1.28 | The role of atrial natriuretic peptide in natriuresis of fasting. ( Maoz, E; Peleg, E; Rosenthal, T; Salzberg, M; Shamiss, A, 1992) |
" Therefore, after 4 weeks of washout with placebo (phase 1), doxazosin (dosage range from 1 to 16 mg, plus hydrochlorothiazide when necessary) was given to 11 essential hypertensive patients (6 M, 5 F, age range 34-63 years) for 8 weeks (phase 2) in order to achieve diastolic blood pressure values less than 90 mmHg; this dosage was then maintained for a further 20 weeks up to the end of the study (phase 3)." | 1.28 | Reduction of left ventricular hypertrophy after longterm antihypertensive treatment with doxazosin. ( Agabiti-Rosei, E; Beschi, M; Calebich, S; Castellano, M; Muiesan, G; Muiesan, ML; Rizzoni, D; Zulli, R, 1992) |
"Aldosterone-producing adenomas (Conn's syndrome) are also commonly composed of zona fasciculata-like cells, make "hybrid steroids" in excess and are very sensitive to ACTH but not to angiotensin II." | 1.28 | Primary aldosteronism: hypertension with a genetic basis. ( Gordon, RD; Klemm, SA; Stowasser, M; Tunny, TJ, 1992) |
"Hence, cardiac hypertrophy during chronic exposure to cold is supported by other factors, possibly by the increased concentration of either norepinephrine or triiodothyronine, or both, which occurs characteristically in rats under these conditions." | 1.28 | Effect of a reduction in sodium intake on cold-induced elevation of blood pressure in the rat. ( Fregly, MJ; Papanek, PE; van Bergen, P, 1992) |
"In patients with MPGN, the levels of total renin (TR) and inactive renin (IR) were significantly higher than in those suffering from MSPGN." | 1.28 | [The morphofunctional parallels in arterial hypertension in patients with chronic glomerulonephritis]. ( Degtereva, OA; Gadaev, A; Kaiukov, IG; Kotovoĭ, IuO; Kucher, AG; Riabov, SI, 1992) |
"Thromboxane A2 has opposite effects." | 1.28 | Renin-angiotensin-aldosterone system and thromboxane A2/prostacyclin in normotensive and hypertensive black Zimbabweans. ( Mufunda, JJ; Somova, LI, 1992) |
"3." | 1.28 | Concurrence of primary aldosteronism and renal artery stenosis. ( Gordon, RD; Grunstein, H; Monaghan, JC; Roche, J; Stokes, GS, 1992) |
"Aldosterone was analyzed by radioimmunoassay and [4-14C]aldosterone radiometabolites by high-performance liquid chromatography." | 1.28 | Aldosterone metabolism in the isolated perfused liver of R and S hypertension-prone Dahl rats. ( Egfjord, M; Olgaard, K, 1992) |
"Aldosterone-salt treatment produced decreased vascular sensitivity to acetylcholine and nitroprusside in both Wistar and Wistar-Furth rats." | 1.28 | Vascular responsiveness in rats resistant to aldosterone-salt hypertension. ( Bruner, CA, 1992) |
"Aldosterone was increased in the SHR-S strain compared with the SHR-R strain on the low NaCl diet, but aldosterone was not different between the two strains on the high NaCl diet." | 1.28 | Adrenocorticosteroid excretion in salt-sensitive and salt-resistant spontaneously hypertensive rats. ( Griffing, GT; Holbrook, M; Melby, JC; Wilson, TC; Wyss, MJ, 1992) |
"Captopril treatment should be introduced carefully since not all those patients at risk of hypotension can be identified in advance." | 1.28 | First dose hypotension after captopril; can it be predicted? A study of 240 patients. ( de Boo, T; Dennesen, PJ; Postma, CT; Thien, T, 1992) |
"Nitrendipine is a calcium antagonist of the dihydropiridine group that may be given once daily." | 1.28 | Regression of cardiovascular structural changes after long-term antihypertensive treatment with the calcium antagonist nitrendipine. ( Agabiti-Rosei, E; Beschi, M; Castellano, M; Muiesan, ML; Rizzoni, D; Romanelli, G, 1991) |
" Chronic administration of spironolactone prevented the development of hypertension but failed to prevent other adaptive physiological changes characteristically occurring during exposure to cold and seen in the cold-treated control rats." | 1.28 | Effect of chronic treatment with clonidine and spironolactone on cold-induced elevation of blood pressure. ( Baron, A; Fregly, MJ; Riesselmann, A, 1991) |
"A peculiar form of hyperaldosteronism is the glucocorticoid-remediable subtype." | 1.28 | New aspects of mineralocorticoid hypertension. ( Armanini, D; Biason, A; Boscaro, M; Carpenè, G; Fallo, F; Mantero, F; Opocher, G; Rocco, S; Scaroni, C; Sonino, N, 1990) |
" HPC-EC10 (5:3) microcapsules containing piretanide were satisfactory as a sustained-release preparation in the light of the anti hypertensive effect even at a half frequency of daily dosing of the solution." | 1.28 | Pharmacological evaluation of hydroxypropylcellulose-ethylcellulose microcapsules containing piretanide. ( Goto, S; Kawata, M; Kuriki, T; Suzuki, N; Tsujiyama, T, 1990) |
"Essential hypertension is not a pathophysiologically homogenous disease with respect to reactivity and interaction of plasma catecholamines and PRA." | 1.28 | Relationship between plasma catecholamines and the renin-aldosterone system during exercise in normal and essential hypertensive subjects. ( Bultas, J; Jindra, A; Savliková, J, 1990) |
"In conclusion, hypertension is a common problem in acromegaly and at least in part related to similar risk factors in control populations." | 1.28 | Acromegaly and hypertension: prevalence and relationship to the renin-angiotensin-aldosterone system. ( Benker, G; Hirche, H; Kraatz, C; Lüdecke, D; Reinwein, D; Weber, F, 1990) |
"Aldosterone was preferentially metabolized to THA in LRH." | 1.28 | Alterations in aldosterone secretion and metabolism in low renin hypertension. ( Griffing, GT; Melby, JC; Wilson, TE, 1990) |
"Aldosterone treatment resulted in an increase in blood pressure to 165 +/- 5 mmHg over the control value of 105 +/- 2 mmHg within 3 wk of experimental period." | 1.28 | Effects of antimineralocorticoid RU 26752 on steroid-induced hypertension in rats. ( Agarwal, M; Corley, K; Kalimi, M; Opoku, J, 1990) |
"Nonmodulating hypertension is characterized, in part, by a decreased aldosterone response to AII, raising the possibility that an increased dopaminergic inhibition of aldosterone secretion underlies the adrenal defect in nonmodulating hypertension." | 1.28 | Dopamine and nonmodulating hypertension. ( Conlin, PR; Gordon, MS; Hollenberg, NK; Stuenkel, CA; Williams, GH, 1990) |
" The purpose of the present study was to examine whether long-term therapy with ramipril (RA, and ACE inhibitor) would lower blood pressure more effectively and without adverse reactions in combination with the loop diuretics piretanide (PI) or furosemide (FU)." | 1.28 | Loop diuretics combined with an ACE inhibitor for treatment of hypertension: a study with furosemide, piretanide, and ramipril in spontaneously hypertensive rats. ( Baldes, L; Becker, RH; Treudler, M, 1989) |
"1." | 1.28 | Endogenous digoxin-like immunoreactive factor and digitalis-like factor associated with the hypertension of patients receiving multiple alkylating agents as part of autologous bone marrow transplantation. ( Antman, KH; Brena, A; Eder, JP; Graves, SW; Peters, WP; Schryber, SM; Sharma, K, 1989) |
"Bopindolol was given to hypertensive patients in a single daily dose ranging from 1 to 4 mg." | 1.28 | Bopindolol: long-term effects on blood pressure, renal function, plasma renin activity, and plasma aldosterone in mild-to-moderate essential hypertension. ( Modan, M; Rosenfeld, JB; Shohat, J, 1989) |
"Aldosterone levels were most strongly related inversely to duration of diabetes, diabetic retinopathy, parasympathetic neuropathy and directly to diastolic blood pressure and glomerular filtration rate." | 1.28 | Relationships between renin, aldosterone, blood pressure and renal function in hypertensive insulin-dependent diabetes mellitus. ( Baker, R; Waldek, S; Winocour, PH, 1989) |
"Postoperatively the signs of hyperaldosteronism (Conn's syndrome) regressed and the average blood pressure was 112/76 mm Hg." | 1.28 | [Primary hyperaldosteronism without arterial hypertension]. ( Andrassy, K; Buhr, H; Osterziel, KJ; Raue, F; Vecsei, P; Zeier, M; Ziegler, R, 1989) |
"The pharmacokinetic parameters of unchanged plasma captopril and the kinetics of the drug effects on plasma converting enzyme activity (PCEA), plasma renin activity (PRA), plasma aldosterone (PA) and mean blood pressure (MBP) were studied over 24 h after oral administration in three groups of hypertensive patients: with normal renal function (group 1, plasma creatinine less than 110 mumol/l, n = 10), with moderate chronic renal failure (group 2, 135 less than plasma creatinine less than 450 mumol/l, n = 10) and with severe chronic renal failure (group 3, plasma creatinine greater than 500 mumol/l, n = 10)." | 1.27 | Influence of chronic renal failure on captopril pharmacokinetics and clinical and biological effects in hypertensive patients. ( Chaignon, M; Giroux, B; Giudicelli, JF; Guedon, J; Richer, C, 1984) |
"Minoxidil was used in 48 patients with AH of varying clinical forms, 19 of those having the malignant AH syndrome." | 1.27 | [Use of angiotensin converting enzyme inhibitor captopril and peripheral vasodilator minoxidil in the treatment of patients with stable and malignant arterial hypertension]. ( Arabidze, GG; Kutsenko, AI; Leshchinskiĭ, PM; Lordkipanidze, NL; Masenko, VP, 1983) |
"Although secondary hyperaldosteronism due to renal vein thrombosis may occur as a result of renal cell carcinoma or adrenal cortical carcinoma, primary hyperaldosteronism is rarely associated with the latter." | 1.27 | Adrenal cortical carcinoma: an unusual cause of hyperaldosteronism. ( Telner, AH, 1983) |
"Most diagnostic tests for primary aldosteronism use maneuvers to expand the extracellular fluid volume, thereby suppressing the renin-angiotensin system." | 1.27 | Single dose captopril as a diagnostic test for primary aldosteronism. ( Brown, RD; Carollo, ML; Hanson, CS; Kem, DC; Lyons, DF, 1983) |
"A definite diagnosis of primary aldosteronism cannot be made during toxemia of pregnancy, and it is necessary to do serial determinations of plasma renin activity and plasma aldosterone concentration after delivery to confirm the diagnosis." | 1.27 | Elevation of plasma renin activity during pregnancy and rupture of a dissecting aortic aneurysm in a patient with primary aldosteronism. ( Akahoshi, M; Aoi, W; Doi, Y; Hashiba, K; Kuramochi, M; Shimizu, A; Suzuki, S; Utsunomiya, T, 1983) |
"Her condition was diagnosed as primary aldosteronism without hypertension, which is very rare, based on an increased level of plasma aldosterone concentration, low plasma renin activity, and a typical finding of aldosterone-producing adenoma by adrenal scintigraphy." | 1.27 | A case of normotensive primary aldosteronism--comparison with 13 previously experienced cases with hypertension. ( Iimura, O; Kikuchi, K; Nakamura, Y; Nishimiya, T; Oimatsu, H; Ota, S; Shimamoto, K, 1984) |
"Atenolol was orally given to 10 patients with essential hypertension once a day and changes in various parameters were observed through 24 hours." | 1.27 | Acute effect of atenolol on hemodynamic, plasma renin activity and plasma aldosterone concentration in the once daily oral administration. ( Arakawa, K; Sasaki, Y, 1984) |
"Primary aldosteronism is a potentially curable cause of hypertension; it occurs in about 1% of hypertensive patients." | 1.27 | 'Essential' hypertension with hypokalemia. Caused by aldosterone-secreting adrenal adenoma. ( Almog, C; Burke, M; Papo, J; Stavorovsky, M, 1984) |
"Thirty-four patients with untreated Conn's syndrome were studied in a metabolic ward." | 1.27 | Relation of blood pressure with body and plasma electrolytes in Conn's syndrome. ( Beretta-Piccoli, C; Brown, JJ; Davies, DL; Ferriss, B; Fraser, R; Lasaridis, A; Lever, AF; Morton, JJ; Robertson, JI; Semple, PF, 1983) |
"Arotinolol (S-596, ARL) is a beta-adrenoceptor blocking drug with weak alpha-adrenoceptor blocking activity, and may be classified into the fourth generation." | 1.27 | Chronic effects of arotinolol (S-596) in spontaneously hypertensive rats. ( Kawashima, K; Kishi, K; Saito, K; Sokabe, H, 1985) |
"Ketanserin is a serotonin antagonist with high affinity for S2-serotonergic receptors, which mediate the vasoconstrictor effects of serotonin." | 1.27 | Ketanserin: a possible tool for studying the role of serotonin in hypertension. ( Boomsma, F; Man in't Veld, AJ; Schalekamp, MA; Wenting, GJ; Woittiez, AJ, 1985) |
"25 mg and increasing dosage until blood pressure was adequately controlled." | 1.27 | Changes in the pathophysiologic profile of blood pressure determinants during short-term enalapril administration. ( Birkenhäger, WH; de Leeuw, PW, 1986) |
"Systolic hypertension has emerged as another serious side effect in our experience." | 1.27 | Hypertension during extracorporeal membrane oxygenation: cause, effect, and management. ( Cullen, ML; Klein, MD; Lerner, GR; Sell, LL; Shanley, CJ; Whittlesey, GC, 1987) |
" These results demonstrate that chronic administration of ANF not only reduces blood pressure and PRA in 2-K, 1-C hypertensive rats but also plasma and urinary aldosterone." | 1.27 | Effect of chronic infusion of atrial natriuretic factor on plasma and urinary aldosterone, plasma renin activity, blood pressure and sodium excretion in 2-K, 1-C hypertensive rats. ( Cantin, M; Garcia, R; Gutkowska, J; Thibault, G, 1986) |
"Further volume expansion in liver cirrhosis by saline infusion led to the further increase in ANP (13." | 1.27 | Radioimmunoassay of atrial natriuretic peptide in human plasma: application to studies of volume and blood pressure homeostasis. ( Horký, K; Lachmanová, J; Srámková, J; Tesar, V; Widimský, J, 1988) |
"Hyperaldosteronism was associated with the most pronounced deviations in the relationship between stimulants and aldosterone." | 1.27 | [Concentration of adrenocorticotrophic hormone and aldosterone secretion in essential hypertension and hyperaldosteronism]. ( Chikhladze, NM; Pershakova, LP; Shkhvatsabaia, IK; Uchitel', IA; Ustinova, SE, 1985) |
"Enalapril (MK-421) was administered orally as a single dose of 2." | 1.27 | Effect of enalapril on renin, angiotensin converting enzyme activity, aldosterone and prostaglandins in patients with hypertension. ( Genest, J; Gutkowska, J; Hamet, P; Kuchel, O; Larochelle, P; Schiffrin, E, 1985) |
"Mean captopril doses used were similar in both groups." | 1.27 | Effects of converting enzyme inhibition on blood pressure, plasma renin activity (PRA) and plasma aldosterone in hypertensive diabetics compared to patients with essential hypertension. ( Dineen, M; Kelleher, M; Sullivan, PA; Twomey, M, 1985) |
"Cushing's syndrome is the consequence of a sustained overproduction of cortisol (hydrocortisone) by the adrenal cortex." | 1.27 | Diagnosis and pathophysiology of Cushing's syndrome. ( Gabrilove, JL; Krakoff, LR, 1986) |
"Treatment with spironolactone alone for 2 months corrected hypertension, hypokalemic alkalosis, and all laboratory and radiologic evidence of rickets and hyperparathyroidism, resulting in acceleration of growth rate." | 1.27 | Spironolactone-reversible rickets associated with 11 beta-hydroxysteroid dehydrogenase deficiency syndrome. ( Arnhold, IJ; Batista, MC; Bloise, W; Kater, CE; Mendonça, BB; Nicolau, W; Rocha, A, 1986) |
" In patients with severe renal failure, adjustment of the dose or the dosing frequency to the degree of renal failure is recommended to avoid administration of doses in excess of those required to achieve adequate inhibition of converting enzyme." | 1.27 | Lisinopril in hypertensive patients with and without renal failure. ( Boer, P; Geyskes, GG; van Schaik, BA, 1987) |
" Enalapril in a dosage of 20 mg/day significantly and progressively lowered systolic and diastolic blood pressure at rest, with maximal decreases observed on the 120th day of the study period (P less than 0." | 1.27 | Effects of enalapril maleate on blood pressure, renin-angiotensin-aldosterone system, and peripheral sympathetic activity in essential hypertension. ( Carapelle, E; Carone, MB; Cerasola, G; Contorno, A; Cottone, S; D'Ignoto, G; Grasso, L, 1987) |
" Although the group data support a reduction in peripheral sympathetic tone as associated with the decrease in BP for the thermal biofeedback condition, dose-response relations were not significant." | 1.27 | Biochemical changes associated with thermal biofeedback treatment of hypertension. ( Blanchard, EB; McCoy, GC; Morrison, S; Pallmeyer, TP; Pangburn, L; Siracusa, K; Wittrock, DA, 1988) |
"Aldosterone excretion was in HL with EH substantially lower, and sodium excretion higher, than in a comparable group of lowland inhabitants." | 1.27 | Prevalence and clinical peculiarities of essential hypertension in a population living at high altitude. ( Dzhumagulova, AS; Meimanaliev, TS; Mirrakhimov, MM; Murataliev, TM; Rafibekova, ZhS; Shatemirova, KK, 1985) |
"Aldosterone and dopamine were measured in the adrenal capsular portions (mostly zona glomerulosa) by radio-immunoassay and high-performance liquid chromatography, respectively." | 1.27 | Dopamine and aldosterone in adrenal glomerulosa cells in spontaneously hypertensive rats. ( Atarashi, K; Hayakawa, H; Hirata, Y; Matsuoka, H; Sugimoto, T; Takagi, M, 1988) |
"Aldosterone was lower (p less than 0." | 1.27 | Sodium sensitivity in human subjects. Hemodynamic and hormonal correlates. ( Ratts, TE; Sullivan, JM, 1988) |
"Aldosterone only was elevated in 3 cases, while PRA was elevated in 2." | 1.27 | The pattern of plasma renin activity and aldosterone system in patients with sustained hydronephrosis. ( Ezzat, M, 1987) |
" In vitro dose-response curves to NE and TNS were not significantly different." | 1.27 | Effect of high calcium intake on pressor responsivity in hypertensive rats. ( Berger, M; Brickman, AS; Eggena, P; Golub, M; Lee, DB; Nyby, M; Stern, N; Tuck, ML, 1987) |
"Hyperaldosteronism in the patients with renal-parenchymatous and essential arterial hypertension was regarded as secondary in a stable and malignant course of arterial hypertension." | 1.27 | [Radioimmunologic determination of aldosterone and renin in the blood in the diagnosis of different forms of arterial hypertension]. ( Khalmuratova, RA; Khamidov, RI; Sattarova, FK, 1987) |
"The treatment with nifedipine induced a significant reduction in both systolic and diastolic blood pressures; the infusions of angiotensin II (0." | 1.27 | Calcium antagonists and responsiveness of the adrenal glands to aldosterone-releasing stimuli in hypertensive patients. ( Leonetti, G; Terzoli, L; Zanchetti, A, 1987) |
" Dose-response studies on the icvt infusion of ALD were carried out in sensitized and non-sensitized (intact, with tap water to drink) male Sprague-Dawley rats (SDR)." | 1.27 | Dose-response studies of intracerebroventricular infusion of aldosterone in sensitized and non-sensitized rats. ( Gomez Sanchez, EP, 1988) |
"Essential hypertension is thought to produce a uniform exaggerated natriuresis and diuresis." | 1.27 | Spectrum of deranged sodium homeostasis in essential hypertension. ( Epstein, M; Levinson, R; Loutzenhiser, R, 1986) |
") alone or in combination with furosemide (1 mg/kg, i." | 1.27 | The effects of acebutolol alone and in combination with furosemide or hydralazine in experimentally induced hypertensive G-minipigs. ( Hidaka, H; Sawada, S; Tanioka, Y; Yasuda, Y, 1986) |
"Hypertension is a common finding in patients with Cushing's syndrome (CS), but the cause is unknown." | 1.27 | Elevated urinary 19-Nor-deoxycorticosterone glucuronide in Cushing's syndrome. ( Ehlers, ME; Griffing, GT; Melby, JC; Wilson, TE, 1987) |
"Minoxidil treatment lowered blood pressure from 178/112 +/- 8/5 mm Hg (means +/- SEM) to 14/95 +/- 6/3 mm Hg." | 1.26 | Treatment of drug-resistant hypertension with minoxidil or angiotensin-converting enzyme inhibitor: blood pressure, renin, aldosterone, and electrolyte responses. ( Baer, L; Radichevich, I; Williams, GS, 1980) |
"Captopril was given in biweekly, doubling doses starting with 25 mg 3 times a day until control of blood pressure was achieved or a total daily dosage of 600 mg was reached." | 1.26 | Dose response in captopril therapy of hypertension. ( Amery, A; Fagard, R; Lijnen, P; Staessen, J; Verschueren, LJ, 1980) |
"Aldosterone secretion was temporarily suppressed after dexamethasone administration and was stimulated by exogenous ACTH." | 1.26 | Primary aldosteronism due to unilateral adrenal hyperplasia. ( Ganguly, A; Luetscher, JA; Zager, PG, 1980) |
"Captopril was given to pregnant and nonpregnant animals during the developmental phase of hypertension and to nonpregnant animals with established (4 weeks of treatment) hypertension." | 1.26 | Aldosterone-induced hypertension: effects of a kininase inhibitor. ( Douglas, BH; Evans, TA; Lundy, JH; Parks, BR, 1980) |
"Aldosterone levels were unresponsive to variations in dietary salt intake and plasma renin activity was suppressed." | 1.26 | Dexamethasone suppressible hyperaldosteronism in a child with nephrosclerosis. ( Lee, SM; Levine, L; Lightner, E; New, MI; Oberfield, S; Witte, M, 1982) |
"Enalapril was well tolerated." | 1.26 | Effects of enalapril, a new converting enzyme inhibitor, in hypertension. ( Ferguson, RK; Hichens, M; Huber, PB; Irvin, JD; Mojaverian, P; Swanson, BN; Vlasses, PH, 1982) |
"PGF2 alpha was the same in preeclampsia and normotensive pregnancy but higher than in the non-pregnant group." | 1.26 | Prostaglandins, catecholamines, renin and aldosterone during hypertensive and normotensive pregnancy. ( Christensen, NJ; Christensen, P; Johannesen, P; Kornerup, HJ; Kristensen, S; Lauritsen, JG; Leyssac, PP; Pedersen, EB; Rasmussen, AB; Wohlert, M, 1982) |
"Screening tests for primary aldosteronism were compared in 22 patients with this disorder and 140 hypertensive controls." | 1.26 | Simplified screening procedures for primary aldosteronism. Studies on the mechanism of the hyper-responsiveness to furosemide and standing. ( Anderson, GH; Streeten, DH, 1982) |
"Aldosterone excretion was established to be normal in 55." | 1.26 | [Urinary excretion of aldosterone in patients with hypertension]. ( Elenkova, A; Grigorova, R, 1982) |
"Captopril was used in primary and long-term treatment of 40 treatment-resistant hypertensive patients." | 1.26 | Long-term efficacy of captopril in renovascular and essential hypertension. ( Atlas, SA; Case, DB; Laragh, JH; Marion, RM, 1982) |
"We report a case of primary hyperaldosteronism in a 37-year-old woman presenting early in pregnancy with hypertension and hypokalaemia." | 1.26 | Primary hyperaldosteronism in pregnancy. ( Buchanan, JD; Hammond, TG; Scoggins, BA; Thatcher, R; Whitworth, JA, 1982) |
"Twenty-four patients with primary aldosteronism were studied." | 1.26 | Fludrocortisone suppression test in normal subjects, in patients with essential hypertension and in patients with various forms of aldosteronism. ( Lund, JO; Nielsen, MD, 1980) |
"In primary aldosteronism, high UA and PAC together with suppressed PRA represent an important diagnostic guideline for differentiation from other types of low-renin hypertensions." | 1.26 | Renin-angiotensin-aldosterone system in arterial hypertension. ( Gregorová, I; Horký, K, 1980) |
" Both systolic and diastolic blood pressures (BP) decreased significantly during the lower dosage (p < 0." | 1.26 | The renin-aldosterone system in low-dose chlorothiazide treatment of hypertensive subjects. ( Lammintausta, K; Lammintausta, R, 1980) |
"Essential hypertension is not a disease entity, so therefore it is understood that there are several causes of its development." | 1.26 | Different patterns in essential hypertension and possible choice of antihypertensive drugs. ( Koster, M, 1980) |
" With the long-term use of diuretics and various kinds of antihypertensive drugs in the treatment of high blood pressure in patients with PA, normal basal level and responsiveness of PRA were observed." | 1.26 | [Clinical observation of 12 cases of primary aldosteronism, special reference to the diagnostic problem (author's transl)]. ( Hata, S; Ito, Y; Kadena, N; Kunita, H; Nakagawa, K; Nakagawa, S; Obara, T; Okamoto, M; Suzuki, H, 1980) |
"Captopril (SQ 14." | 1.26 | Captopril in primary hypertension. Effects related to the renin-angiotensin-aldosterone and kallikrein-kinin systems. ( Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S, 1981) |
"Hypertension was uncommon when bilateral nephrectomy had been performed." | 1.26 | Hypertension following renal transplantation: the role of the host's kidney. ( Liano, F; Marcen, R; McHugh, MI; Robson, V; Tanboga, H; Wilkinson, R, 1980) |
"Spironolactone was indicated preoperatively for all surgical candidates, for non-operated APA patients, and for all IHA patients." | 1.26 | Primary aldosteronism -- screening, diagnosis and therapy. ( Gregorová, I; Horký, K; Hradec, E; Silinková-Málková, E; Vancura, J, 1981) |
"1." | 1.26 | Effect of angiotensin II and converting enzyme inhibitor (captopril) on blood pressure, plasma renin activity and aldosterone in primary aldosteronism. ( Armanini, D; Boscaro, M; Fallo, F; Mantero, F; Opocher, G; Scaroni, C, 1981) |
"Thus screening for primary aldosteronism can be restricted to hypokalaemic patients." | 1.26 | Simple screening procedure for the diagnosis of primary aldosteronism. ( Giese, J; Lund, JO; Nielsen, MD, 1981) |
"1 Labetalol was administered to 18 hypertensive patients for an average duration of 2." | 1.26 | Response of the systemic pulmonary circulation to labetalol at rest and during exercise. ( Amery, A; Fagard, R; Lijnen, P, 1982) |
"Low-renin hypertension was diagnosed by the presence of hypertension, hypokalaemic alkalosis, suppressed plasma renin activity and low plasma aldosterone." | 1.26 | Low-renin, low-aldosterone hypertension and abnormal cortisol metabolism in a 19-month-old child. ( Fiselier, TJ; Honour, JW; Monnens, LA; Otten, BJ; van Munster, PJ, 1982) |
"Deoxycorticosterone (DOC) levels were significantly lower at 8 weeks and 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) were lower at 16 weeks of age." | 1.26 | Role of adrenal steroidogenesis in etiology of hypertension in the spontaneously hypertensive rat. ( Dale, SL; Komanicky, P; Melby, JC; Reiss, DL, 1982) |
" The syndrome was iatrogenic in two cases depending on the licorice eating and the combined use of diuretics and a 9-alpha-fluoroprednisolone-containing nasal spray in one patient, and on a long-term use of the same nasal decongestant in the other." | 1.26 | [Hypokalemic myopathy in arterial hypertension]. ( Angeletti, G; Filipponi, P; Natali, P; Nicoletti, I; Nunzi, E; Rambotti, P; Santeusanio, F, 1982) |
"In most of the patients examined hyperaldosteronism was found, which was attended by an increased percentage of 14C-aldosterone binding with aldosterone binding globulin (ABG) and particularly with glucocorticoid binding globulin (GBG)." | 1.26 | [14C-aldosterone binding by plasma proteins in adolescents with primary arterial hypertension]. ( Bakova, VV; Golov, AG; Kucherenko, AG; Markov, KhM, 1981) |
"Amiloride was disproportionately potent in lowering serum bicarbonate, and the data do not suggest that these drugs elevate plasma potassium simply by correcting metabolic alkalosis." | 1.26 | Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients. ( Fraser, R; Hettiarachchi, J; Morton, JJ; Ramsay, LE, 1980) |
"Propranolol therapy was associated with a 25% decrease in PRA (p less than 0." | 1.26 | Effects of propranolol on aldosterone plasma concentration and aldosterone metabolic clearance in hypertensive patients. ( Grim, CE; Parkinson, CA; Pratt, JH, 1980) |
"Hyperparathyroidism and hyperaldosteronism coexisted in association with medullary sponge kidneys in a 27-year-old woman with severe hypertension." | 1.26 | Hyperaldosteronism, hyperparathyroidism, medullary sponge kidneys, and hypertension. ( Hellman, DE; Kartchner, M; Komar, N; Mayes, D; Pitt, M, 1980) |
"Aldosterone-oxime was labelled with 125I by using the chloramine T method described by Hunter and Greenwood." | 1.26 | [A simple method for measuring aldosterone secretion rate using 125I-aldosterone (authors' transl)]. ( Fukuchi, S; Haruyama, K; Toki, T; Yamazaki, M, 1980) |
"Two of nine patients with primary aldosteronism had normal Also-18-G excretion but elevated TH-Aldo excretion." | 1.26 | Urinary tetrahydroaldosterone and aldosterone-18-glucuronide excretion in white and black normal subjects and hypertensive patients. ( Gomez-Sanchez, CE; Holland, OB, 1981) |
"Four patients with hyperaldosteronism due to adrenal adenomas served as controls." | 1.26 | The role of ACTH in the episodic release of aldosterone in patients with idiopathic adrenal hyperplasia, hypertension, and hyperaldosteronism. ( Gomez-Sanchez, C; Higgins, JR; Kem, DC; Kramer, NJ; Weinberger, MH, 1976) |
"High aldosterone was more often in patients with high renin, and low levels of aldosterone were usual in those with low and normal renin." | 1.26 | The mechanism of low-renin hypertension: aldosterone response to sodium restriction and upright posture, angiotensin II, ACTH and potassium in patients with hypertension. ( Kondo, K; Matsuki, S; Misumi, J; Nakamura, R; Saito, I; Saruta, T, 1976) |
"The hypothesis that hyperaldosteronism is not the sole cause of hypertension in dexamethasone-suppressible hyperaldosteronsim was tested in an 18-year-old male." | 1.26 | Evidence for an unidentified ACTH-induced steroid hormone causing hypertension. ( Levine, LS; New, MI; Peterson, RE; Saenger, P, 1976) |
"Primary hyperaldosteronism usually causes moderate hypertension." | 1.26 | [Primary hyperaldosteronism with paroxysmal arterial hypertension. Apropos of 2 operated cases]. ( Griffe, J; Morin, PP; Tatibouet, L, 1978) |
"These data show that patients with hyperaldosteronism from an adrenal adenoma or hyperplasia have a consistent and exaggerated response to ACTH." | 1.26 | Plasma aldosterone response to ACTH in primary aldosteronism and in patients with low renin hypertension. ( Gomez-Sanchez, C; Higgins, JR; Holland, OB; Kem, DC; Kramer, NJ; Weinberger, MH, 1978) |
"Aldosterone levels were subnormal but as yet there has been no evidence of overproduction of other mineralocorticoids by chemical analysis or by bioassay of plasma and urinary extracts." | 1.26 | A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol. ( Bradlow, HL; Gunczler, P; Levine, LS; New, MI; Ramirez, LC; Rauh, W; Rösler, A; Ulick, S; Zanconato, G, 1979) |
"The effects of hydralazine (3 mg/kg) and the angiotensin I-converting enzyme (ACE) inhibitor captopril (SQ 14,225) (100 mg/kg) on mean arterial blood pressure, plasma renin activity, urinary volume and urinary Na+,K+, and aldosterone concentrations were examined in spontaneously hypertensive rats of the Okamoto and Aoki strain (SHR) after oral daily dosing for 2 weeks, 3 or 6 months." | 1.26 | Effects of chronic treatment with captopril (SQ 14,225), an orally active inhibitor of angiotensin I-converting enzyme, in spontaneously hypertensive rats. ( Antonaccio, MJ; Goldberg, ME; Harris, DN; High, JP; Horovitz, ZP; Laffan, RJ; Rubin, B; Zaidi, I, 1979) |
"2." | 1.26 | The natural history of hypertension in turkeys. ( Dal Palù, C; Pagnan, A; Pessina, AC; Thiene, G, 1978) |
"1." | 1.26 | Effects of labetalol on systemic and pulmonary haemodynamics at rest and during exercise in hypertensive patients. ( Amery, A; Billiet, L; Fagard, R; Lijnen, P; Reybrouck, T, 1978) |
""Outpatient hyperkalemia" is a new clinical syndrome in which high serum potassium levels (SK) are found in the outpatient condition returning toward normal without any specific treatment after admission to the hospital." | 1.26 | "Outpatient hyperkalemia" syndrome in renal and hypertensive patients with suppressed aldosterone production. ( Boer, P; Dorhout Mees, EJ; Rado, JP; Simatupang, T, 1979) |
"Post-transplant hypertension has been observed in 98 renal allograft recipients who had good renal function and whose follow-up was more than 15 months." | 1.26 | Late hypertension following renal allotransplantation. ( Beaudoin, JG; Guttmann, RD; Klassen, J; Knaack, J; Morehouse, DD; Pollini, J, 1979) |
"Patients with proved aldosteronism are outside the normal ranges of plasma renin activity." | 1.26 | Evaluation of patients for secondary hypertension. ( Donohue, JP; Grim, CE; Weinberger, MH, 1979) |
"Experimental toxemia of pregnancy was induced in 8 pregnant monkeys (Macacamulatta) by reducing the abdomiinal aorta to one-third of its original diameter during the last month of gestation." | 1.26 | Experimental toxemia of pregnancy in the monkey, with a preliminary report on renin and aldosterone. ( Abitbol, MM; Driscoll, SG; Gallo, GR; Ober, MB; Pirani, CL, 1977) |
" The findings indicate that different regulatory mechanisms are activated during acute and chronic administration of nifedipine." | 1.26 | Effect of nifedipine on plasma renin, aldosterone and catecholamines in arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Mikkelsen, E; Pedersen, EB; Pedersen, OL, 1979) |
"1." | 1.26 | Blood pressure reduction by incremental infusion of labetalol in patients with severe hypertension. ( Brown, JJ; Cummings, AM; Fraser, R; Lever, AF; Morton, JJ; Richards, DA; Robertson, JI, 1979) |
" The data shows that this dosage of spironolactone gave minor adjustments of the systemic and renal circulation in spite of the consistent changes in BW, PV, PRA and PA." | 1.26 | Haemodynamic effects of treatment and withdrawal of spironolactone in essential hypertension. ( Falch, DK; Johansson, R; Norman, N; Odegaard, AE, 1979) |
"Triamterene was administered in a dose of 100 mg/day for 8 days to 7 patients with essential hypertension." | 1.26 | Effect of triamterene on urinary excretion of immunoreactive prostaglandin E in essential hypertension. ( Abe, K; Chiba, S; Irokawa, N; Ito, T; Otsuka, Y; Saito, K; Sakurai, Y; Sato, M; Yasujima, M; Yoshinaga, K, 1979) |
"Treatment with spironolactone did not significantly alter the natriuretic response of the spontaneously hypertensive rats (43 +/- 8 mueq/h) to another salt load, but increased the natriuretic response of the normotensive rats (55 +/- 7 mueq/h) to that of the hypertensive rats." | 1.26 | Aldosterone in the exaggerated natriuresis of spontaneously hypertensive rats. ( Bauer, JH; Willis, LR, 1978) |
"Of these, 13 had primary aldosteronism (ALDO), 19 high renin (HRH), 30 low renin (LRH), and 57 normal renin (NRH) essential hypertension." | 1.26 | Natriuretic response to saline infusion in normotensive and hypertensive man. The role of renin suppression in exaggerated natriuresis. ( Grim, CE; Higgins, JT; Luft, FC; Weinberger, MH; Willis, LR, 1977) |
"The hypertension was accompanied by expansion of plasma volume, retention of sodium, and alteration in urinary Na/K ratio." | 1.26 | Isolation of a hypertension-producing compound from normal human urine. ( Bravo, EL; Bumpus, FM; Sen, S, 1977) |
"Aldosterone excretion was low." | 1.26 | Steroid profile in a case of adrenal carcinoma with severe hypertension. ( Forman, BH; Genel, M; Mulrow, PJ; Tan, SY, 1977) |
"Twenty patients suffering from primary hyperaldosteronism were studied." | 1.26 | [The renin-angiotensin-aldosterone system in hypertensive patients. II. Diagnosis of primary hyperaldosteronism]. ( Benguigui, L; Corvol, P; Houde, M; Menard, J; Milliez, P; Tonnelier, M, 1977) |
"We examined the acute and chronic dose-response relationships between intravenously infused angiotensin II (A II) and the resulting changes in arterial pressure and plasma aldosterone concentration at varying levels of sodium intake." | 1.26 | Acute and chronic dose-response relationships for angiotensin, aldosterone, and arterial pressure at varying levels of sodium intake. ( Cowley, AW; McCaa, RE, 1976) |
" In normal subjects, Sar1-Ile-AII showed pressor (agonistic) activity, which was related to both dosage and sodium intake." | 1.26 | Changes of blood pressure, plasma renin activity and plasma aldosterone concentration following the infusion of Sar1-Ile8-angiotensin II in hypertensive, fluid and electrolyte disorders. ( Doi, K; Hata, T; Ichihara, K; Kumahara, Y; Ogihara, T; Yamamoto, T, 1976) |
"In spironolactone-treated rats blood pressure and total aortic renin concentrations were comparable with those in the control rats." | 1.26 | Effects of aldosterone and spironolactone on arterial renin in rats. ( Rosenthal, J, 1976) |
"In two patients with primary hyperaldosteronism, the aldosterone excretion during the night was relatively more elevated than in the day." | 1.26 | [Diurnal variation in the urinary excretion of vanilmandelic acid and aldosterone in normal and hypertensive persons (author's transl)]. ( Deck, KA; Eberlein, L; Luedtke, A, 1976) |
"Hypertension was produced in 25 rabbits by constricting the right renal artery and leaving the opposite kidney intact (two-kidney hypertension)." | 1.26 | Renin-angiotensin-aldosterone system in experimental renal hypertension in the rabbit. ( Davis, JO; Lohmeier, TE, 1976) |
"Hypokalemic hypertension is the leading symptome of the disease." | 1.26 | [Primary aldosteronism]. ( Beckerhoff, R; Braun, KP; Furrer, J; Nussberger, J; Pouliadis, G; Siegenthaler, W; Sobbe, A; Vetter, H; Vetter, W; Witassek, F, 1976) |
"Low-renin hypertension was not characterized by increased exchangeable sodium, but exchaneable postassium was significantly lower than in patients with normal plasma-renin." | 1.25 | Is low-renin hypertension a stage in the development of essential hypertension or a diagnostic entity? ( Beevers, DG; Brown, JJ; Davies, DL; Lever, AF; Padfield, PL; Robertson, JI; Schalekamp, MA; Tree, M, 1975) |
"Aldosterone secretion was elevated markedly in dexamethasone-morphine-treated spontaneously hypertensive rats at both 7-8 and 11-13 weeks of age but was not significantly different from control in 22-25-week-old spontaneously hypertensive rats." | 1.25 | Control of aldosterone secretion in the spontaneously hypertensive rat. ( Aharon, NV; Davis, JO; Freeman, RH; Ulick, S; Weinberger, MH, 1975) |
"Propranolol was given to 10 hypertensive patients with CGN and hypotensive effect on renal function was observed." | 1.25 | Therapy and prognosis of hypertension in chronic nephritis. ( Kajiwara, N, 1975) |
"Five obvious cases of hyperaldosteronism were found among the 16 low-renin patients." | 1.25 | Abnormally sustained aldosterone secretion during salt loading in patients with various forms of benign hypertension; relation to plasma renin activity. ( Collins, RD; Dowdy, AJ; Gonzales, CM; Luetscher, JA; Nokes, GW; Weinberger, MH, 1970) |
"Hypertension was initially ameliorated but was not cured." | 1.25 | Periodic hypokalaemic paralysis, adrenal adenoma, and normal colonic transport of sodium and potassium. ( Jones, MB; Peart, WS; Richards, P, 1973) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2321 (45.47) | 18.7374 |
1990's | 690 (13.52) | 18.2507 |
2000's | 802 (15.71) | 29.6817 |
2010's | 852 (16.69) | 24.3611 |
2020's | 439 (8.60) | 2.80 |
Authors | Studies |
---|---|
Liu, X | 5 |
Jin, L | 1 |
Zhang, H | 6 |
Ma, W | 1 |
Song, L | 3 |
Zhou, X | 4 |
Cai, J | 2 |
Perrin, EC | 1 |
South, AM | 2 |
Carides, MD | 1 |
Sishuba, NT | 1 |
Bombil, I | 1 |
Christofides, C | 1 |
Veldhuizen, GP | 6 |
Alnazer, RM | 6 |
de Leeuw, PW | 23 |
Kroon, AA | 9 |
Memon, SS | 1 |
Lila, A | 1 |
Barnabas, R | 1 |
Goroshi, M | 1 |
Sarathi, V | 1 |
Shivane, V | 1 |
Patil, V | 1 |
Shah, N | 1 |
Bandgar, T | 1 |
Betz, MJ | 1 |
Zech, CJ | 1 |
Tang, WW | 1 |
Ma, WX | 1 |
Sun, SY | 1 |
Ran, XW | 1 |
Hu, Z | 1 |
Chen, X | 5 |
Shao, Y | 1 |
Luo, FX | 1 |
Chu, SL | 3 |
Wang, JG | 6 |
Hundemer, GL | 9 |
Imsirovic, H | 2 |
Vaidya, A | 19 |
Yozamp, N | 3 |
Goupil, R | 2 |
Madore, F | 2 |
Agharazii, M | 2 |
Knoll, G | 2 |
Sood, MM | 2 |
Chen, HH | 4 |
Wan, SH | 1 |
Iyer, SR | 2 |
Cannone, V | 3 |
Sangaralingham, SJ | 5 |
Nuetel, J | 1 |
Burnett, JC | 10 |
Gromotowicz-Poplawska, A | 2 |
Flaumenhaft, R | 1 |
Gholami, SK | 3 |
Merrill-Skoloff, G | 1 |
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Artz, W | 1 |
Jansen, W | 1 |
Doorenbos, H | 1 |
Miyazaki, G | 1 |
Sasano, N | 1 |
Kelch, RP | 1 |
Connors, MH | 1 |
Kaplan, SL | 1 |
Grumbach, MM | 1 |
Vaisrub, S | 1 |
Guest, S | 1 |
Shtel'makh, NI | 1 |
Kamyshan, NA | 1 |
Ashcheulova, IK | 1 |
Gavrik, TI | 1 |
Hitzenberger, G | 1 |
Kovacs, K | 2 |
Horvath, E | 1 |
Piyasena, RD | 1 |
Ekins, RP | 1 |
Feldman, D | 1 |
Vaccaro, E | 1 |
Solitro, A | 1 |
McCaa, CS | 1 |
Miyahara, M | 1 |
Kukuiri, T | 1 |
Sai, Z | 3 |
Weil, MH | 1 |
Shubin, H | 1 |
Toussaint, C | 1 |
Naets, JP | 1 |
Corvilain, J | 1 |
Lambert, PP | 1 |
Seaman, MP | 1 |
Koshikawa, S | 1 |
Shiigai, T | 1 |
Ideura, T | 1 |
Kategawa, H | 1 |
Nielsen, I | 2 |
Moller, I | 1 |
Păun, R | 1 |
Ionescu-Tîrgovişte, C | 1 |
Mićić, R | 1 |
Lebedev, VP | 1 |
Vodolazhskaia-Levina, EE | 1 |
Chemidze, NP | 1 |
Khovanskaia, MP | 1 |
Kalashnikova, OA | 1 |
Aitchison, J | 1 |
Johns, VJ | 1 |
Bhatia, S | 1 |
Koppes, G | 1 |
Luton, JP | 1 |
Laudat, P | 1 |
Lemmer, M | 1 |
Nowaczynski, WJ | 1 |
Ferencíková, J | 1 |
Baláz, V | 1 |
Marek, J | 2 |
Slabý, A | 1 |
Wisenbaugh, PE | 1 |
Hull, C | 1 |
Freedman, RJ | 1 |
Matthews, DN | 1 |
Hadady, M | 1 |
James, IM | 1 |
Imada, A | 1 |
Hammann, K | 1 |
Fischer, N | 1 |
Castleman, B | 1 |
Scully, RE | 1 |
McNeely, BU | 1 |
Amsterdam, EA | 2 |
Dobrzinsky, SJ | 2 |
Finnerty, FA | 1 |
Cashion, WR | 1 |
Nugent, CA | 2 |
Mulrow, RJ | 1 |
Morrow, LB | 1 |
Shutkin, PM | 1 |
Marieb, N | 1 |
Yorifuji, S | 1 |
Kahn, PC | 2 |
Kelleher, MD | 1 |
Egdahl, BH | 1 |
Eversman, JJ | 1 |
Humphrey, DC | 1 |
Peters, TJ | 1 |
Maher, JF | 1 |
Meneuvonen, PJ | 1 |
Salvadori, B | 1 |
Gould, AB | 1 |
Kusla, J | 1 |
Luciak, M | 1 |
Gasiński, J | 1 |
Wilson, DR | 1 |
Skelton, FR | 1 |
Gunnells, CJ | 1 |
Stickel, DL | 1 |
Robinson, RR | 2 |
Frankhuyzen, AL | 1 |
Witter, A | 1 |
Balikian, H | 1 |
Brodie, A | 1 |
Willoughby, S | 1 |
Yoshinaga, H | 1 |
Chinn, RH | 1 |
Düsterdieck, GO | 1 |
Gleadle, RH | 1 |
Moeller, J | 1 |
Tsai, ZH | 1 |
Castiglioni, GC | 1 |
Gennari, R | 1 |
Dinç, I | 1 |
Barlas, O | 1 |
Chiappino, G | 1 |
Baroni, M | 1 |
Margolin, AH | 1 |
Stocks, LO | 1 |
Conn, J | 1 |
Simon, NM | 1 |
Bergan, JJ | 1 |
Baumber, JS | 1 |
Torres, M | 1 |
Manta, I | 2 |
Hodîrnău, A | 2 |
Băltescu, V | 2 |
Proinov, I | 2 |
Schneider, E | 2 |
Lloyd, IJ | 2 |
Kahuho, SK | 1 |
Mulimba, O | 1 |
Webala, GS | 1 |
Enger, E | 1 |
Arnesen, E | 1 |
Geddes, RA | 1 |
Pawsey, CG | 1 |
O'Halloran, MW | 1 |
Ludwig, RN | 1 |
Goldsmith, RF | 1 |
Starr, LM | 1 |
Gentle, JL | 3 |
Mani, MK | 1 |
Stewart, JH | 2 |
Nelson, J | 1 |
Schley, G | 1 |
Bock, KD | 2 |
Hocevar, V | 1 |
Merguet, P | 2 |
Rausch-Stroomann, JG | 2 |
Schröder, E | 2 |
Schümann, HJ | 2 |
Wells, S | 1 |
Silver, D | 1 |
Jacobsen, J | 1 |
Renner, D | 1 |
Stant, EG | 1 |
Brill, AB | 1 |
Biddle, CM | 1 |
Londe, S | 1 |
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Barbi, G | 1 |
Giocoli, G | 1 |
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Sardini, D | 1 |
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Migeon, CJ | 2 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Prevalence of Primary Aldosteronism in Patients With Stroke[NCT03789357] | 300 participants (Actual) | Observational | 2018-05-01 | Completed | |||
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Parallel-Group, Dose-Ranging Study to Evaluate the Efficacy and Safety of Multiple Dose Strengths of CIN-107 as Compared to Placebo After 12 Weeks of Treatment in Patients With Treatment-Resista[NCT04519658] | Phase 2 | 275 participants (Actual) | Interventional | 2020-10-12 | Completed | ||
Radiofrequency Ablation for Aldosterone-producting Adenoma in Patients With Primary Aldosteronism: Evaluation of the Blood Pressure Control and of Its Safety.[NCT02756754] | 31 participants (Actual) | Interventional | 2016-11-07 | Completed | |||
[NCT00000608] | Phase 2 | 0 participants | Interventional | 1997-02-28 | Completed | ||
Electronic Alert-Based Computerized Decision Support to Improve Testing For Primary Aldosteronism in Patients With Hypertension: ALERT-PA[NCT05925569] | 1,600 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | |||
Resident Doctor, Master Degree Candidate[NCT05991856] | 45 participants (Anticipated) | Observational | 2020-01-01 | Recruiting | |||
Preoperative Supine Time for Adrenal Venous Sampling: A Prospective Randomized Controlled Trial[NCT05658705] | 120 participants (Anticipated) | Interventional | 2023-03-29 | Recruiting | |||
Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension[NCT05593055] | Phase 4 | 75 participants (Anticipated) | Interventional | 2023-08-25 | Recruiting | ||
Efficacy and Safety of Percutaneous Superselective Adrenal Arterial Embolization in the Treatment of Primary Aldosteronism With Bilateral Idiopathic Hyperaldosteronism: A Prospective Cohort Study[NCT05186675] | 50 participants (Anticipated) | Interventional | 2022-01-01 | Enrolling by invitation | |||
The Long-term Effect of Superselective Adrenal Arterial Embolization and Medical Treatment for Primary Aldosteronism on Cardiorenovascular Protection, Blood Pressure, and the Endocrinological Profile.[NCT05262660] | 400 participants (Anticipated) | Observational [Patient Registry] | 2022-04-01 | Not yet recruiting | |||
HyperAldosteronism in Pregnancy Predicted Impacts[NCT05636995] | 200 participants (Anticipated) | Observational [Patient Registry] | 2023-01-10 | Recruiting | |||
Glucose Metabolism in Subjects With Aldosterone-Producing Adenomas[NCT02362308] | 10 participants (Actual) | Observational | 2015-01-31 | Completed | |||
Effectiveness and Safety of Superselective Adrenal Arterial Embolization (SAAE) for Resistant Hypertension: A Randomized, Parallel, Controlled Clinical Trial[NCT05552300] | 144 participants (Anticipated) | Interventional | 2022-10-01 | Not yet recruiting | |||
Salt Sensitive Hypertension and Striatin[NCT03683069] | Phase 4 | 400 participants (Actual) | Interventional | 2019-01-15 | Active, not recruiting | ||
An Open-label, Prospective, Controlled Clinical Trial on Effects and Safety of Adrenal Artery Ablation (Triple A) for Primary Aldosteronism[NCT03398785] | Phase 3 | 66 participants (Actual) | Interventional | 2017-10-01 | Completed | ||
African Prospective Study for the Early Detection and Identification of Cardiovascular Disease and Hypertension (African-PREDICT Study)[NCT03292094] | 1,202 participants (Actual) | Observational | 2013-02-04 | Active, not recruiting | |||
"The RADIANCE-HTN Study. A Study of the ReCor Medical Paradise System in Clinical Hypertension"[NCT02649426] | 292 participants (Anticipated) | Interventional | 2016-03-31 | Active, not recruiting | |||
Prospective Assessment of The Prevalence of Primary Aldosteronism in Hypertensive Patients Presenting With Atrial Flutter or Fibrillation[NCT01267747] | 411 participants (Actual) | Observational | 2015-01-31 | Completed | |||
CPAP Effect on Nocturnal Evolution of Chemosensitivity Determinants in Sleep Apnea-hypopnea Patients With Isolated Nocturnal Hypertension or Day-nigh Sustained Hypertension[NCT02398032] | Phase 4 | 32 participants (Actual) | Interventional | 2013-05-31 | Completed | ||
Vascular Function Markers: Differences Between Lean and Abdominally Overweight / Obese Men and Effects of Weight Loss[NCT01675401] | 75 participants (Actual) | Interventional | 2012-09-30 | Completed | |||
Optimum Treatment for Drug-Resistant Hypertension[NCT02369081] | Phase 4 | 348 participants (Actual) | Interventional | 2009-05-31 | Active, not recruiting | ||
Effect of Mineralcorticoid Recept Antagonist on Cardiovascular Disease in Patients With Hypertension and Hyperaldosteronemia:A Multicenter Randomized Controlled Study[NCT05688579] | Phase 4 | 8,000 participants (Anticipated) | Interventional | 2023-04-16 | Enrolling by invitation | ||
A Safety and Feasibility Study of Water-only Fasting and Refeeding for Treatment of Stage 1 and 2 Hypertensive Patients[NCT04515095] | 30 participants (Actual) | Interventional | 2020-08-16 | Completed | |||
Effects of Mineralocorticoid and AT-1 Receptor Antagonism on the Aldosterone-Renin Ratio (ARR) In Primary Aldosteronism Patients (EMIRA Study): Rationale and Design[NCT04185857] | 50 participants (Actual) | Observational | 2018-01-01 | Completed | |||
The Effect of Low Salt Diet on CKD Progression:A Randomized Controlled Trial[NCT05716386] | 200 participants (Actual) | Interventional | 2023-02-28 | Completed | |||
A Phase II, Randomized, Double-blind, Placebo Controlled, Multi-center Study to Evaluate the Effects of LCI699 on Cortisol in Patients With Hypertension[NCT00817414] | Phase 2 | 63 participants (Actual) | Interventional | 2009-01-14 | Completed | ||
A Multi-center, Randomized, Double-blind, Placebo and Active Controlled, Parallel Group, Dose Finding Study to Evaluate the Efficacy and Safety of LCI699 Compared to Placebo After 8 Weeks Treatment in Patients With Essential Hypertension[NCT00758524] | Phase 2 | 628 participants (Actual) | Interventional | 2008-09-11 | Completed | ||
A Phase II, Randomized, Double-blind, Placebo and Active Controlled, Parallel Group, Multi-center, Dose Ranging Study to Evaluate the Efficacy and Safety of LCI699 Compared to Placebo After 8 Weeks Treatment in Patients With Resistant Hypertension[NCT00817635] | Phase 2 | 155 participants (Actual) | Interventional | 2008-12-22 | Completed | ||
A Pilot, Single-blind, Forced-titration Study to Assess the Hemodynamic and Hormonal Effects, Safety and Tolerability of the Aldosterone Synthase Inhibitor LCI699 in Patients With Primary Hyperaldosteronism[NCT00732771] | Phase 2 | 12 participants (Anticipated) | Interventional | 2008-06-30 | Completed | ||
Southern Danish Hypertension and Diabetes Study (SDHDS) With Amiloride[NCT02122731] | Phase 4 | 80 participants (Actual) | Interventional | 2010-11-30 | Completed | ||
Mineralocorticoid Receptor and Obesity Induced Cardiovascular Complications[NCT01406015] | 38 participants (Actual) | Interventional | 2009-02-28 | Completed | |||
Aldosterone and Glucose Homeostasis[NCT00732160] | 34 participants (Actual) | Interventional | 2008-09-30 | Completed | |||
Caveolin-1 and Vascular Dysfunction[NCT01426529] | Phase 1 | 120 participants (Anticipated) | Interventional | 2010-10-01 | Active, not recruiting | ||
Serum Levels of Advanced Glycation End-products After Dietary Intervention in Hypertensive Patients: Study Protocol of a Randomized Clinical Trial.[NCT02848677] | Phase 2 | 120 participants (Anticipated) | Interventional | 2015-11-30 | Recruiting | ||
Safety, Success Rate and Long Term Consequences of Renal Denervation in Patients With Therapy Resistant Hypertension. The Dutch National Renal Denervation Registry[NCT02482103] | 1,000 participants (Anticipated) | Observational [Patient Registry] | 2013-04-30 | Recruiting | |||
HALT Progression of Polycystic Kidney Disease Study B[NCT01885559] | Phase 3 | 486 participants (Actual) | Interventional | 2006-01-31 | Completed | ||
Characteristics Predicting Clinically Relevant Reduction of Hypertension Following Adrenalectomy for Primary Aldosteronism: a Multicenter Analysis[NCT04761354] | 514 participants (Actual) | Observational | 2016-03-26 | Completed | |||
LC-MS/MS-specific Cutoffs for Screening and Confirmatory Testing of Primary Aldosteronism: A Multi-center Study[NCT05959863] | 300 participants (Anticipated) | Observational | 2023-08-30 | Recruiting | |||
Increasing Stay-on-therapy in Hypertensive Patients Treated With First-line Diuretics: An Active Pharmacosurveillance and Pharmacogenetic Study.[NCT00408512] | Phase 4 | 2,500 participants (Anticipated) | Interventional | 2006-12-31 | Completed | ||
Identification of New Biomarkers for the Classification and Monitoring of Difficult-to-treat Arterial Hypertension: Prospective Observational Study[NCT03034265] | 24 participants (Actual) | Observational | 2016-05-31 | Completed | |||
A 4-Week, Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Parallel Group Study To Evaluate The Safety, Tolerability And Efficacy Of Once Daily PF-04971729 And Hydrochlorothiazide In Patients With Type 2 Diabetes Mellitus With Inadequa[NCT01096667] | Phase 2 | 194 participants (Actual) | Interventional | 2010-05-17 | Completed | ||
Effect of Anti-hypertensive Medications on the Diagnostic Accuracy in Screening for Primary Aldosteronism:a Prospective Study[NCT04991961] | 330 participants (Anticipated) | Observational | 2020-09-15 | Recruiting | |||
Table Olives Nutritional Intervention: Pharmacokinetics of Polyphenols and Pentacyclic Triterpenes and Assessment of Antioxidant, Cardiovascular and Anti-inflammatory Biomarkers[NCT03886597] | Phase 1/Phase 2 | 58 participants (Actual) | Interventional | 2019-03-25 | Completed | ||
Comparison of Atorvastatin and Pitavastatin on the Effect of HbA1c in Acute Myocardial Infarction (AMI) Patients With Abnormal Glucose Metabolism: a Multicenter Prospective Randomized Clinical Trial[NCT04945122] | Phase 4 | 900 participants (Anticipated) | Interventional | 2015-10-01 | Recruiting | ||
A Multi-center, Open-label, Randomized, 12-month, Parallel-group, Non-inferiority Study to Compare the Hemoglobin A1C Metabolism of Pitavastatin Therapy Versus Atorvastatin in Chinese Patients With Prediabetes and Hypertension[NCT03532620] | Phase 4 | 396 participants (Anticipated) | Interventional | 2018-08-09 | Recruiting | ||
Effect of Statin Use on Aldosterone Secretion[NCT02871687] | Phase 1 | 103 participants (Actual) | Interventional | 2016-04-30 | Completed | ||
Case Detection and Confirmation, Subtype Classification of Patients With Primary Aldosteronism[NCT02755519] | 300 participants (Actual) | Observational | 2014-05-31 | Completed | |||
Styrian Vitamin D Hypertension Trial: A Randomized, Double-blind, Placebo Controlled Trial to Evaluate the Effects of Vitamin D Supplementation on Systolic Ambulatory Blood Pressure in Vitamin D Deficient Hypertensive Patients[NCT02136771] | Phase 4 | 200 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
68Ga-Pentixafor PET/CT for the Subtyping Diagnosis of Primary Aldosteronism: A Prospective Diagnostic Accuracy Study[NCT05131061] | 100 participants (Actual) | Observational | 2021-11-11 | Completed | |||
Hypertension in High School Students: Genetic and Environmental Factors[NCT06049641] | 2,638 participants (Actual) | Observational | 2014-10-31 | Completed | |||
Phase 4 Study of Losartan in Hypertensive Men and Women With Obstructive Sleep Apnea Before and After Continuous Positive Airway Pressure (CPAP) Treatment[NCT00701428] | Phase 4 | 90 participants (Actual) | Interventional | 2008-06-30 | Completed | ||
Efficacy of Continuous Positive Airway Pressure (CPAP) on Blood Pressure Control of Resistant Hypertension Patients With Obstructive Sleep Apnea Syndrome (OSAS).[NCT01508754] | Phase 4 | 125 participants (Actual) | Interventional | 2012-01-31 | Completed | ||
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE): The Role of Angiotensin-(1-7) in Hypertension and Hypertension-Induced Heart and Kidney Damage[NCT04752293] | 125 participants (Anticipated) | Observational | 2021-05-19 | Recruiting | |||
Dietary Approaches to Stop Hypertension in 'Diastolic' Heart Failure 2 (DASH-DHF 2)[NCT01942395] | 18 participants (Actual) | Interventional | 2012-09-18 | Terminated (stopped due to study diet is no longer available to match with the previous participants.) | |||
Estudio RioplateNsE Sobre Telemonitoreo en hIpertensos No-controlAdos[NCT02730052] | 0 participants (Actual) | Interventional | 2016-12-31 | Withdrawn (stopped due to Centers recruited poorly) | |||
Aspirin AM or PM in Reduction of Tension: a Randomized Cross-over Trial[NCT01379079] | Phase 4 | 290 participants (Actual) | Interventional | 2011-04-30 | Completed | ||
Safety and Efficacy of Fludrocortisone Addition to Dexamethasone in the Management of Hospitalised COVID-19 Patients[NCT05453214] | Phase 3 | 10 participants (Actual) | Interventional | 2021-12-04 | Completed | ||
Effect of Sodium Intake on Calcium Retention in Black and White Adolescent Girls.[NCT01564238] | 67 participants (Actual) | Interventional | 1999-01-31 | Completed | |||
DASH-Sodium Trial in Adolescents[NCT02993458] | 79 participants (Actual) | Interventional | 2016-10-31 | Terminated (stopped due to safety risks to youth in the study required early termination of the study) | |||
[NCT00917345] | 150 participants (Anticipated) | Observational | 2008-01-31 | Recruiting | |||
Towards Cost-effective Management of Patients With Hypertension Due to Primary Aldosteronism: Adrenal Vein Sampling or Ct-scan?[NCT01096654] | Phase 3 | 200 participants (Actual) | Interventional | 2010-07-31 | Completed | ||
Multicenter Study on Use and Interpretation of Adrenal Vein Sampling[NCT01234220] | 2,604 participants (Actual) | Observational | 2010-05-31 | Completed | |||
Prospective Cross-sectional Study on Prevalence of Primary Aldosteronism in Resistant Hypertension and Association With Cardiometabolic Complications[NCT04213963] | 100 participants (Anticipated) | Observational | 2011-09-01 | Recruiting | |||
A Double Blind, Dose Range, Placebo Controlled Study of the Effects of Rostafuroxin vs Placebo in Patients With Stable, Uncomplicated, Essential Hypertension.[NCT00415038] | Phase 2 | 438 participants (Actual) | Interventional | 2005-02-28 | Completed | ||
Macrolides for KCNJ5 - Mutated Aldosterone-Producing Adenoma (MAPA): A Study Of Personalized Diagnosis of Primary Aldosteronism With Implications For Treatment[NCT03414918] | 342 participants (Anticipated) | Interventional | 2018-03-31 | Not yet recruiting | |||
A Blinded Crossover Study of the 24 Hour Blood Pressure Response to Treatment of Obstructive Sleep Apnea Associated Hypertension With Nebivolol or Hydrochlorothiazide[NCT02710071] | Phase 4 | 41 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
A Placebo Controlled Double Blinded Crossover Study of the Antihypertensive Efficacy of Guanfacine vs Hydrochlorothiazide in Obstructive Sleep Apnea (OSA) Associated Hypertension[NCT02699125] | Phase 4 | 41 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
Genetic Based Analysis of Identifying Predictors of Blood Pressure Response in Hypertensive Patients After Renal Denervation[NCT04321044] | 300 participants (Actual) | Interventional | 2019-01-01 | Active, not recruiting | |||
Efficiency of Speech Therapy in Resistant Hypertensive Patients With Mild Obstructive Sleep Apnea Syndrome[NCT03753633] | 50 participants (Anticipated) | Interventional | 2017-10-01 | Active, not recruiting | |||
A 36-week, Randomized, Double-blind, Multi-center, Parallel Group Study Comparing the Efficacy and Safety of Aliskiren in Combination With Losartan Compared to Losartan on the Regression of Left Ventricular Hypertrophy in Overweight Patients With Essentia[NCT00219141] | Phase 3 | 460 participants (Actual) | Interventional | 2005-10-31 | Completed | ||
Lysine-specific Demethylase 1 and Salt-sensitivity in Humans[NCT03029806] | 88 participants (Anticipated) | Interventional | 2017-01-02 | Active, not recruiting | |||
Oral Sodium to Preserve Renal EfficiencY in Acute Heart Failure (OSPREY-AHF)[NCT04334668] | 70 participants (Actual) | Interventional | 2020-05-20 | Active, not recruiting | |||
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Essential Hypertension, During Basal Conditions and After Hypertonic Saline Infusion.[NCT00345124] | 50 participants (Actual) | Interventional | 2006-05-31 | Completed | |||
Technology Assisted Management of Uncontrolled Hypertension (TEAM-HTN): a Pilot Study[NCT03281772] | 180 participants (Anticipated) | Observational | 2017-01-24 | Recruiting | |||
Phase III, Single-Center, Open Label, Trial Evaluating the Safety and Efficacy of PectaSol-C Modified Citrus Pectin on PSA Kinetics in Prostate Cancer in the Setting of Serial Increases in PSA[NCT01681823] | Phase 2 | 60 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
The Pathophysiology and Treatment of Supine Hypertension in Patients With Autonomic Failure[NCT00223717] | Phase 1 | 152 participants (Actual) | Interventional | 2001-01-31 | Completed | ||
Anesthesiological Strategies in Elective Craniotomy: Randomized, Equivalence, Open Trial[NCT00741351] | Phase 3 | 411 participants (Actual) | Interventional | 2007-12-31 | Completed | ||
Comparison of the Analgesic Effects of Scalp Nerve Block and Intravenous Ibuprofen Applications Under the Guidance of Nociception Level Index (NoL) in Patients Undergoing Elective Supratentorial Craniotomy[NCT05763836] | Phase 4 | 102 participants (Anticipated) | Interventional | 2022-11-01 | Recruiting | ||
A Triple-Blind, Parallel Study to Investigate the Effect of Losartan Versus Atenolol on the Reduction of Morbidity and Mortality in Hypertensive Patients With Left Ventricular Hypertrophy[NCT00338260] | Phase 3 | 496 participants (Actual) | Interventional | 1995-06-30 | Completed | ||
Genetic Epidemiology of Responses to Antihypertensives[NCT00005520] | 1,200 participants (Actual) | Observational | 1997-02-28 | Completed | |||
The Prevalence and the Prognosis of Resistant Hypertension Ascertained With Systemic Investigation and Optimal Treatment With Antihypertensive Drugs[NCT01703780] | 9,638 participants (Actual) | Observational | 2012-07-31 | Active, not recruiting | |||
[NCT00005181] | 0 participants | Observational | 2000-07-31 | Completed | |||
Short-Term Oral Mifepristone for Central Serous Chorioretinopathy. A Placebo-controlled Dose Ranging Study of Mifepristone in the Treatment of CSC (STOMP-CSC)[NCT02354170] | Phase 2 | 16 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
Is Spironolactone Safe and Effective in the Treatment of Cardiovascular Disease in Mild Chronic Renal Failure?[NCT00291720] | Phase 2 | 120 participants (Actual) | Interventional | 2005-04-30 | Completed | ||
Randomized Trial of Spironolactone Versus Amiloride as an Add on Agent in Resistant Hypertension[NCT00709137] | 0 participants (Actual) | Interventional | 2008-10-31 | Withdrawn (stopped due to lack of enrollment) | |||
South Danish Hypertension and Diabetes Study[NCT01062763] | Phase 3 | 119 participants (Actual) | Interventional | 2010-03-31 | Completed | ||
Effects of Nebivolol Versus Metoprolol on Blood Flow Responses to Exercise and Angiotensin II in Hypertensive Patients[NCT01502787] | Phase 4 | 46 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
Aldosterone-Renin Ratio to Diagnose Primary Aldosteronism in a Population of Patients With Therapy-Resistant Hypertension: Test Characteristics, Diagnostic Value and Predictive Value for Antihypertensive Treatment. The Dutch ARRAT Study.[NCT00407784] | 500 participants | Observational | 2007-01-31 | Recruiting | |||
BNP Pharmacodynamics and Effects on Metabolism in Lean and Obese Subjects[NCT01977859] | Phase 1 | 4 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
Effect of Nesiritide Infusion on Insulin Sensitivity in Healthy Obese Insulin Resistant Subjects[NCT03234751] | Phase 1 | 6 participants (Actual) | Interventional | 2017-07-13 | Completed | ||
Pilot Study to Assess Blockade of Calcium Channels and Sodium Chloride Cotransporters for Physiologic Abnormalities in Liver Transplant Associated Hypertension[NCT05275907] | Phase 4 | 0 participants (Actual) | Interventional | 2022-07-12 | Withdrawn (stopped due to Screened participants did not meet inclusion criteria prior to study completion date) | ||
The Effectiveness of an Educational Intervention for Sodium Restriction in Patients With Hypertension: Study Protocol for a Randomized Controlled Trial[NCT02848690] | 120 participants (Anticipated) | Interventional | 2015-11-30 | Recruiting | |||
China Salt Substitute Study in Tibet: Efficacy of Salt Substitute in Reducing Blood Pressure in Hypertensive Adults[NCT01429246] | 282 participants (Actual) | Interventional | 2009-02-28 | Completed | |||
The Intra-Procedural Cortisol Assay During Adrenal Vein Sampling: Rationale andDesign of A Randomized Study (I-PADUA)[NCT03449797] | 200 participants (Anticipated) | Interventional | 2018-04-01 | Not yet recruiting | |||
Genes of Hypertension in African Americans[NCT00063505] | 5,000 participants (Actual) | Observational | 2002-12-31 | Completed | |||
Comparison of Saline Infusion Test, Captopril Challenge Test, and Oral Sodium Loading Test in the Diagnosis of Primary Aldosteronism[NCT04193137] | 200 participants (Actual) | Observational | 2019-11-30 | Completed | |||
Prospective Evaluation of Confirmatory Testing For Primary Aldosteronism[NCT04422756] | 200 participants (Anticipated) | Observational | 2017-01-15 | Recruiting | |||
Case Detection and Confirmation, Subtype Classification of Patients With Primary Aldosteronism[NCT03500120] | 200 participants (Actual) | Observational | 2017-09-01 | Completed | |||
The Role of Aldosterone on Sympathetic Nerve Activity and Insulin Sensitivity[NCT02102243] | Phase 4 | 0 participants (Actual) | Interventional | 2010-11-30 | Withdrawn (stopped due to No longer interested in study topic) | ||
Usefulness of the Ipsilateral and Contralateral Index for the Interpretation of Adrenal Vein Sampling (AVS) in the Subtype Diagnosis of Primary Aldosteronism[NCT04378387] | 60 participants (Actual) | Observational | 2005-01-01 | Completed | |||
Randomized Double-Blind Placebo-Controlled Study of Pyrazinoylguanidine Hydrochloride (Amiloride) in Subjects With Coronary Artery Disease[NCT01228214] | Phase 2/Phase 3 | 100 participants (Actual) | Interventional | 2011-03-31 | Active, not recruiting | ||
[NCT00005138] | 0 participants | Observational | 1976-06-30 | Completed | |||
A Clinical Trial of Renin Profiling in Selection of Initial Antihypertensive Drug[NCT00834600] | 185 participants (Actual) | Interventional | 2005-12-31 | Completed | |||
The Function of Dopaminergic and Noradrenergic Systems in Salt-Sensitive Hypertension: The Effects of Changes in Sodium Intake[NCT00001176] | 110 participants | Observational | 1981-05-31 | Completed | |||
Autonomic Imbalance and 24-h Blood Pressure Change in Patients With Chronic Renal Disease[NCT00298129] | 278 participants (Actual) | Observational | 2004-02-29 | Completed | |||
Efficacy of L-arginine Treatment on Blood Pressure Control Patients With Stage 1 Hypertension[NCT02894723] | Phase 4 | 40 participants (Anticipated) | Interventional | 2016-09-30 | Not yet recruiting | ||
Kidney Dopamine Effects on Urinary Sodium Excretion in Postural Tachycardia Syndrome[NCT00685919] | Phase 2/Phase 3 | 32 participants (Actual) | Interventional | 2008-05-31 | Completed | ||
[NCT00005394] | 0 participants | Observational | 1995-08-31 | Completed | |||
LOVE-COARCT Study: Long-term Outcomes and Vascular Evaluation After Coarctation of the Aorta Treatment[NCT03262753] | 90 participants (Anticipated) | Observational | 2013-06-01 | Recruiting | |||
Resistant Hypertension On Treatment - Sequential Nephron Blockade Compared to Dual Blockade of the Renin-angiotensin-aldosterone System Plus Bisoprolol in the Treatment of Resistant Arterial Hypertension: A Randomized Trial (ResHypOT)[NCT02832973] | Phase 4 | 72 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
Renin System Responses to Combined Renin Inhibition and Beta Adrenergic Blockade[NCT00627861] | 1 participants (Actual) | Interventional | 2008-11-30 | Terminated (stopped due to The renin laboratory used in the study is no longer available.) | |||
Pilot Study of Cardiac Magnetic Resonance in Patients With Muscular Dystrophy[NCT02921321] | 100 participants (Anticipated) | Observational | 2014-01-31 | Active, not recruiting | |||
Randomized, Controlled Pilot Trial of Domperidone in Relapsing-Remitting Multiple Sclerosis[NCT02493049] | Phase 2 | 17 participants (Actual) | Interventional | 2015-08-31 | Completed | ||
Addressing HyperteNsion and Diabetes Through Community-Engaged Systems in Puno, Peru (ANDES Study)[NCT05524987] | 1,068 participants (Anticipated) | Interventional | 2022-11-30 | Not yet recruiting | |||
[NCT00155064] | Phase 4 | 100 participants (Anticipated) | Interventional | 2002-07-31 | Completed | ||
Childhood Obesity: Variations in Management[NCT00160914] | 500 participants (Actual) | Observational | 2001-12-31 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
(NCT04519658)
Timeframe: 12 weeks
Intervention | mmHg (Mean) |
---|---|
mITT Population 0.5mg | -9.1 |
mITT Population 1mg | -11.7 |
mITT Population 2mg | -14.0 |
mITT Population Placebo | -9.3 |
(NCT04519658)
Timeframe: 12 weeks
Intervention | mmHg (Mean) |
---|---|
mITT Population 0.5mg | -12.4 |
mITT Population 1mg | -17.3 |
mITT Population 2mg | -19.2 |
mITT Population Placebo | -9.8 |
(NCT04519658)
Timeframe: 12 weeks
Intervention | Participants (Count of Participants) |
---|---|
mITT Population 0.5mg | 21 |
mITT Population 1mg | 28 |
mITT Population 2mg | 26 |
mITT Population Placebo | 21 |
(NCT00817414)
Timeframe: Days 7, 28: Pre-dose and 3 hours post-dose; Day 30: Pre-dose; Day 42: Pre-dose and 0.5, 1, 2, 3, 4, and 8-hours post-dose
Intervention | hr (Geometric Mean) |
---|---|
Cohort A: LCI699 0.5 mg QD | 4.67 |
Cohort A: LCI699 1.0 mg QD | 3.79 |
Cohort B1: LCI699 1.0 mg BID | 5.52 |
Cohort B1: LCI699 2.0 mg QD | 4.90 |
(NCT00817414)
Timeframe: Day 42: Pre-dose and 0.5, 1, 2, 3, 4, and 8-hours post-dose
Intervention | nanogram*hour per milliliter (ng*hr/mL) (Geometric Mean) |
---|---|
Cohort A: LCI699 0.5 mg QD | 6.60 |
Cohort A: LCI699 1.0 mg QD | 14.1 |
Cohort B1: LCI699 1.0 mg BID | 24.1 |
Cohort B1: LCI699 2.0 mg QD | 46.4 |
(NCT00817414)
Timeframe: Days 7, 28: Pre-dose and 3 hours post-dose; Day 30: Pre-dose; Day 42: Pre-dose and 0.5, 1, 2, 3, 4, and 8-hours post-dose
Intervention | ng*hr/mL (Geometric Mean) |
---|---|
Cohort A: LCI699 0.5 mg QD | 9.23 |
Cohort A: LCI699 1.0 mg QD | 18.8 |
Cohort B1: LCI699 1.0 mg BID | 30.6 |
Cohort B1: LCI699 2.0 mg QD | 68.9 |
(NCT00817414)
Timeframe: Predose and 3 hours post-dose on Day 7
Intervention | nanogram per milliliter (ng/mL) (Geometric Mean) |
---|---|
Cohort A: LCI699 0.5 mg QD | 1.51 |
Cohort A: LCI699 1.0 mg QD | 2.88 |
Cohort B1: LCI699 1.0 mg BID | 3.92 |
Cohort B1: LCI699 2.0 mg QD | 6.73 |
(NCT00817414)
Timeframe: Days 7, 28: Pre-dose and 3 hours post-dose; Day 30: Pre-dose; Day 42: Pre-dose and 0.5, 1, 2, 3, 4, and 8-hours post-dose
Intervention | ng/mL (Geometric Mean) |
---|---|
Cohort A: LCI699 0.5 mg QD | 1.42 |
Cohort A: LCI699 1.0 mg QD | 2.94 |
Cohort B1: LCI699 1.0 mg BID | 4.62 |
Cohort B1: LCI699 2.0 mg QD | 8.86 |
As per the protocol, MTD is the dose at which 4 participants exhibited ACTH-stimulated cortisol results <400 nanomoles per liter (nmol/L). The change in the distribution across the treatments were analyzed using 1- way analysis of variance (ANOVA) for continuous variables. (NCT00817414)
Timeframe: Up to Week 6
Intervention | milligrams (mg) (Number) |
---|---|
LCI699 | 1.30 |
An AE is an adverse medical event which occurs in a participant of the study and which is not necessarily in a causal relationship with the treatment the participant receives. (NCT00817414)
Timeframe: Up to 8 weeks
Intervention | Participants (Count of Participants) |
---|---|
Cohort A: LCI699 0.5 mg QD | 6 |
Cohort A: LCI699 1 mg QD | 9 |
Cohort B1: LCI699 1 mg BID | 10 |
Cohort B1: LCI699 2 mg QD | 10 |
Placebo | 10 |
(NCT00817414)
Timeframe: Days 7, 28: Pre-dose and 3 hours post-dose; Day 30: Pre-dose; Day 42: Pre-dose and 0.5, 1, 2, 3, 4, and 8-hours post-dose
Intervention | hour (hr) (Median) |
---|---|
Cohort A: LCI699 0.5 mg QD | 2.21 |
Cohort A: LCI699 1.0 mg QD | 1.00 |
Cohort B1: LCI699 1.0 mg BID | 1.00 |
Cohort B1: LCI699 2.0 mg QD | 1.00 |
Exposure-response relationship was assessed using ACTH stimulation test. Tests were done 2 hours after study drug administration (i.e., at peak LCI699 concentrations). An increase in cortisol greater than >500 nmol at 60 minutes after ACTH administration was expected. (NCT00817414)
Timeframe: Up to Week 6
Intervention | nanomoles per liter (nmol/L) (Mean) | ||
---|---|---|---|
Day 7 | Day 28 | Day 42 | |
Cohort A: LCI699 0.5 mg QD | 690.0 | 634.87 | 647.51 |
Cohort A: LCI699 1.0 mg QD | 669.40 | 573.41 | 626.08 |
Cohort B1: LCI699 1.0 mg BID | 625.06 | 554.79 | 539.68 |
Cohort B1: LCI699 2.0 mg QD | 562.04 | 539.09 | 479.91 |
Placebo | 799.06 | 804.86 | 812.91 |
Automated arterial BP determinations was made with an automated BP device (such as the Omron BP monitor) in accordance with the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV. Sitting and standing BP and HR measurements were performed. MSDBP response was defined as the percentage of participants with a MSDBP <90 mmHg or a >= 10 mmHg reduction from baseline. MSDBP control was defined as the percentage of participants with a MSDBP <90 mmHg for non-diabetic participants and <80mHg for diabetic participants. (NCT00817414)
Timeframe: Week 6
Intervention | percentage of participants (Number) | |
---|---|---|
MSDBP Response | MSDBP Control | |
Cohort A: LCI699 0.5 mg QD | 58.3 | 58.3 |
Cohort A: LCI699 1 mg QD | 66.7 | 66.7 |
Cohort B1: LCI699 1 mg BID | 100 | 76.9 |
Cohort B1: LCI699 2 mg QD | 76.9 | 76.9 |
Placebo | 61.5 | 46.2 |
Automated arterial BP determinations was made with an automated BP device (such as the Omron BP monitor) in accordance with the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV. Sitting and standing blood pressure (BP) and heart rate (HR) measurements were performed. MSSBP response was defined as the percentage of participants with a MSSBP <140 mmHg or a >=20 mmHg reduction from baseline. MSSBP control was defined as the percentage of participants with a MSSBP <140 mmHg for non-diabetic participants and <130mHg for diabetic participants. (NCT00817414)
Timeframe: Week 6
Intervention | percentage of participants (Number) | |
---|---|---|
MSSBP Response | MSSBP Control | |
Cohort A: LCI699 0.5 mg QD | 58.3 | 50.0 |
Cohort A: LCI699 1 mg QD | 50.0 | 41.7 |
Cohort B1: LCI699 1 mg BID | 69.2 | 61.5 |
Cohort B1: LCI699 2 mg QD | 76.9 | 76.9 |
Placebo | 61.5 | 53.8 |
An ABPM measured a participant's BP over a 24-hour period readings using an automated validated monitoring device from Baseline to Week 8. The 24-hour DBP was calculated by taking the mean of all ambulatory DBP readings for the 24-hour period. (NCT00758524)
Timeframe: Baseline, Week 8
Intervention | mm Hg (Least Squares Mean) |
---|---|
Core Period: LCI699 0.25 mg QD | -4.03 |
Core Period: LCI699 0.5 mg QD | -2.44 |
Core Period: LCI699 1.0 mg QD | -4.96 |
Core Period: LCI699 0.5 mg BID | -2.75 |
Core Period: Eplerenone 50 mg BID | -6.03 |
Core Period: Placebo | 1.03 |
An ABPM measured a participant's BP over a 24-hour period readings using an automated validated monitoring device from Baseline to Week 8. The 24-hour SBP was calculated by taking the mean of all ambulatory SBP readings for the 24-hour period. (NCT00758524)
Timeframe: Baseline, Week 8
Intervention | mm Hg (Least Squares Mean) |
---|---|
Core Period: LCI699 0.25 mg QD | -7.15 |
Core Period: LCI699 0.5 mg QD | -4.90 |
Core Period: LCI699 1.0 mg QD | -7.73 |
Core Period: LCI699 0.5 mg BID | -6.18 |
Core Period: Eplerenone 50 mg BID | -10.52 |
Core Period: Placebo | 1.11 |
Automated arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV, using an automated BP device (such as the Omron BP monitor). The change in the MSDBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from baseline in MSDBP was analyzed using an analysis of covariance model (ANCOVA) with treatment and region as factors and baseline MSDBP level as a covariate. (NCT00758524)
Timeframe: Baseline, Week 8
Intervention | mm Hg (Mean) |
---|---|
Core Period: LCI699 0.25 mg QD | -4.47 |
Core Period: LCI699 0.5 mg QD | -5.50 |
Core Period: LCI699 1.0 mg QD | -7.11 |
Core Period: LCI699 0.5 mg BID | -4.25 |
Core Period: Eplerenone 50 mg BID | -7.49 |
Core Period: Placebo | -3.22 |
Automated arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV, using an automated BP device (such as the Omron BP monitor). The change in the MSSBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from baseline in MSSBP was analyzed using an ANCOVA with treatment and region as factors and baseline MSSBP levels as a covariate. (NCT00758524)
Timeframe: Baseline, Week 8
Intervention | mm Hg (Mean) |
---|---|
Core Period: LCI699 0.25 mg QD | -9.00 |
Core Period: LCI699 0.5 mg QD | -10.69 |
Core Period: LCI699 1.0 mg QD | -11.93 |
Core Period: LCI699 0.5 mg BID | -9.10 |
Core Period: Eplerenone 50 mg BID | -13.31 |
Core Period: Placebo | -2.93 |
Change from baseline was analyzed using plasma aldosterone values measured at Baseline and Week 8. (NCT00758524)
Timeframe: Baseline, Week 8
Intervention | picomoles per liter (pmol/L) (Mean) |
---|---|
Core Period: LCI699 0.25 mg QD | -21.5 |
Core Period: LCI699 0.5 mg QD | -20.0 |
Core Period: LCI699 1.0 mg QD | -9.9 |
Core Period: LCI699 0.5 mg BID | -47.5 |
Core Period: Eplerenone 50 mg BID | 277.1 |
Core Period: Placebo | -28.8 |
The ACTH stimulation cortisol test was a standard procedure to measure the ability of adrenal cortex to respond to exogenous ACTH and directly assess the adrenal reserve. Serum cortisol concentrations at 1 hour after injection were measured to assess the maximum stimulated cortisol level achieved. Potential adrenal suppression was indicated if the serum cortisol concentration was <500 nanomoles per liter (nmol/L) at 1 hour after the injection. (NCT00758524)
Timeframe: Baseline, 1 hour post-dose at Week 8
Intervention | nanomoles per liter (nmol/L) (Mean) |
---|---|
Core Period: LCI699 0.25 mg QD | 729.20 |
Core Period: LCI699 0.5 mg QD | 692.74 |
Core Period: LCI699 1.0 mg QD | 604.46 |
Core Period: LCI699 0.5 mg BID | 609.21 |
Core Period: Eplerenone 50 mg BID | 802.32 |
Core Period: Placebo | 822.65 |
Automated arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV, using an automated BP device (such as the Omron BP monitor). The change in the MSDBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from baseline in MSDBP was analyzed using an analysis of covariance model (ANCOVA) with treatment and region as factors and baseline MSDBP level as a covariate. (NCT00758524)
Timeframe: Baseline, Week 8
Intervention | mm Hg (Mean) |
---|---|
Core Period: LCI699 0.25 mg QD | -4.47 |
Core Period: LCI699 0.5 mg QD | -5.50 |
Core Period: LCI699 1.0 mg QD | -7.11 |
Core Period: LCI699 0.5 mg BID | -4.25 |
Automated arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV, using an automated BP device (such as the Omron BP monitor). The change in the MSSBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from baseline in MSSBP was analyzed using an ANCOVA with treatment and region as factors and baseline MSSBP levels as a covariate. (NCT00758524)
Timeframe: Baseline, Week 8
Intervention | mm Hg (Mean) |
---|---|
Core Period: LCI699 0.25 mg QD | -9.00 |
Core Period: LCI699 0.5 mg QD | -10.69 |
Core Period: LCI699 1.0 mg QD | -11.93 |
Core Period: LCI699 0.5 mg BID | -9.10 |
Automated arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV, using an automated BP device (such as the Omron BP monitor). The change in the MSDBP was calculated comparing the Week 9 readings to the readings taken at Week 8 (Baseline). The change from Week 8 to week 9 in MSDBP was analyzed using an ANCOVA with treatment and region as factors and Week 8 MSDBP level as a covariate. (NCT00758524)
Timeframe: From Week 8 to Week 9
Intervention | mm Hg (Least Squares Mean) |
---|---|
Withdrawal Period: LCI699 0.25 mg QD | 0.5 |
Withdrawal Period: LCI699 0.25 mg QD Placebo | 0.5 |
Withdrawal Period: LCI699 0.5 mg QD | 1.6 |
Withdrawal Period: LCI699 0.5 mg QD Placebo | -0.2 |
Withdrawal Period: LCI699 1.0 mg QD | -0.5 |
Withdrawal Period: LCI699 1.0 mg QD Placebo | 2.5 |
Withdrawal Period: LCI699 0.5 mg BID | 1.3 |
Withdrawal Period: LCI699 0.5 mg BID Placebo | 1.3 |
Withdrawal Period: Eplerenone 50 mg BID | -1.2 |
Withdrawal Period: Eplerenone 50 mg BID Placebo | 0.4 |
Withdrawal Period: Placebo | 1.6 |
Automated arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV, using an automated BP device (such as the Omron BP monitor). The change in the MSSBP was calculated comparing the Week 9 readings to the readings taken at Week 8 (Baseline). The change from Week 8 to week 9 in MSSBP was analyzed using an ANCOVA with treatment and region as factors and Week 8 MSSBP level as a covariate. (NCT00758524)
Timeframe: From Week 8 to Week 9
Intervention | mm Hg (Least Squares Mean) |
---|---|
Withdrawal Period: LCI699 0.25 mg QD | 0.3 |
Withdrawal Period: LCI699 0.25 mg QD Placebo | 3.3 |
Withdrawal Period: LCI699 0.5 mg QD | 0.5 |
Withdrawal Period: LCI699 0.5 mg QD Placebo | 2.5 |
Withdrawal Period: LCI699 1.0 mg QD | 0.4 |
Withdrawal Period: LCI699 1.0 mg QD Placebo | 5.3 |
Withdrawal Period: LCI699 0.5 mg BID | 1.6 |
Withdrawal Period: LCI699 0.5 mg BID Placebo | 4.4 |
Withdrawal Period: Eplerenone 50 mg BID | -1.5 |
Withdrawal Period: Eplerenone 50 mg BID Placebo | 2.7 |
Withdrawal Period: Placebo | 1.8 |
An AE was an adverse medical event which occurs in a participant of the study and which is not necessarily in a causal relationship with the treatment the participant receives. SAEs were AEs leading to death, are life-threatening, require hospitalizations or prolongation of hospitalizations, represent an innate malformation or a congenital abnormality. (NCT00758524)
Timeframe: AEs: From start of the study drug treatment up to 8 weeks; SAE: From signing of the informed consent up to 8 weeks
Intervention | Participants (Count of Participants) | ||
---|---|---|---|
AEs | SAEs | Deaths | |
Core Period: Eplerenone 50 mg BID | 26 | 0 | 0 |
Core Period: LCI699 0.25 mg QD | 23 | 1 | 0 |
Core Period: LCI699 0.5 mg BID | 27 | 0 | 0 |
Core Period: LCI699 0.5 mg QD | 22 | 0 | 0 |
Core Period: LCI699 1.0 mg QD | 24 | 0 | 0 |
Core Period: Placebo | 23 | 1 | 0 |
MSDBP response was defined as the percentage of participants with a MSDBP <90 mmHg or a >=10 mmHg reduction from Baseline. MSDBP control was defined as the percentage of participants with a MSDBP <90 mmHg. (NCT00758524)
Timeframe: Baseline, Week 8
Intervention | percentage of participants (Number) | |
---|---|---|
MSDBP Response | MSDBP Control | |
Core Period: Eplerenone 50 mg BID | 48.8 | 45.2 |
Core Period: LCI699 0.25 mg QD | 39.1 | 32.6 |
Core Period: LCI699 0.5 mg BID | 34.4 | 29.2 |
Core Period: LCI699 0.5 mg QD | 34.1 | 29.4 |
Core Period: LCI699 1.0 mg QD | 50.0 | 41.9 |
Core Period: Placebo | 27.6 | 18.4 |
MSSBP response was defined as the percentage of participants with a MSSBP <140 mmHg or a >=20 mmHg reduction from baseline reduction from baseline. MSSBP control was defined as the percentage of participants with a MSSBP <140 mmHg. (NCT00758524)
Timeframe: Baseline, Week 8
Intervention | percentage of participants (Number) | |
---|---|---|
MSSBP Response | MSSBP Control | |
Core Period: Eplerenone 50 mg BID | 52.4 | 44.0 |
Core Period: LCI699 0.25 mg QD | 39.1 | 31.5 |
Core Period: LCI699 0.5 mg BID | 34.4 | 25.0 |
Core Period: LCI699 0.5 mg QD | 37.6 | 27.1 |
Core Period: LCI699 1.0 mg QD | 48.8 | 40.7 |
Core Period: Placebo | 17.1 | 15.8 |
Trough to peak ratios were derived from an ANCOVA model containing treatment, region, hour, treatment by hour interaction as factors with Baseline as a covariate. (NCT00758524)
Timeframe: Baseline, every hour up to 24 hours post-dose at Week 8
Intervention | ratio (Least Squares Mean) | |||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Week 8, Hour 1 | Week 8, Hour 2 | Week 8, Hour 3 | Week 8, Hour 4 | Week 8, Hour 5 | Week 8, Hour 6 | Week 8, Hour 7 | Week 8, Hour 8 | Week 8, Hour 9 | Week 8, Hour 10 | Week 8, Hour 11 | Week 8, Hour 12 | Week 8, Hour 13 | Week 8, Hour 14 | Week 8, Hour 15 | Week 8, Hour 16 | Week 8, Hour 17 | Week 8, Hour 18 | Week 8, Hour 19 | Week 8, Hour 20 | Week 8, Hour 21 | Week 8, Hour 22 | Week 8, Hour 23 | Week 8, Hour 24 | |
Core Period: Eplerenone 50 mg BID | 0.17 | -1.65 | -2.42 | -1.39 | -2.91 | -4.86 | -3.70 | -2.30 | -2.81 | -2.43 | -1.93 | -3.20 | -5.35 | -7.64 | -9.03 | -12.55 | -12.88 | -13.49 | -10.13 | -10.47 | -10.51 | -7.60 | -5.54 | -2.78 |
Core Period: LCI699 0.25 mg QD | 3.91 | 1.44 | 1.16 | 0.51 | 1.11 | -1.18 | -1.85 | -3.01 | -1.24 | -0.59 | -1.02 | -1.60 | -4.32 | -6.47 | -8.34 | -8.92 | -10.26 | -10.68 | -10.13 | -10.73 | -9.31 | -7.90 | -4.94 | -0.21 |
Core Period: LCI699 0.5 mg BID | 3.87 | 3.44 | 4.01 | 2.64 | 1.45 | 1.20 | 1.21 | 2.09 | 3.27 | 0.49 | 1.54 | -1.06 | -1.45 | -2.96 | -6.10 | -9.54 | -10.38 | -11.85 | -10.78 | -10.49 | -8.22 | -6.35 | -2.67 | 1.36 |
Core Period: LCI699 0.5 mg QD | 2.95 | 1.85 | 1.13 | 2.91 | -0.02 | -2.36 | -0.95 | -1.38 | -0.07 | 2.60 | 1.72 | 2.53 | -1.20 | -3.29 | -5.82 | -8.37 | -10.99 | -11.73 | -10.12 | -8.06 | -7.68 | -4.93 | -1.93 | 1.45 |
Core Period: LCI699 1.0 mg QD | 0.27 | 0.17 | -0.36 | 0.35 | -1.69 | -3.01 | -2.63 | -2.43 | -2.25 | -1.65 | -1.54 | -3.10 | -5.31 | -7.38 | -8.89 | -10.50 | -12.71 | -11.88 | -9.74 | -10.43 | -9.66 | -5.37 | -1.18 | 0.29 |
Core Period: Placebo | 7.11 | 6.28 | 4.99 | 7.02 | 4.31 | 1.82 | 3.62 | 2.65 | 3.30 | 3.86 | 2.38 | 3.24 | 1.52 | -0.90 | -1.01 | -1.61 | -4.20 | -6.89 | -5.84 | -5.21 | -4.12 | -1.09 | 1.82 | 1.98 |
Trough to peak ratios were derived from an ANCOVA model containing treatment, region, hour, treatment by hour interaction as factors with Baseline as a covariate. (NCT00758524)
Timeframe: Baseline, every hour up to 24 hours post-dose at Week 8
Intervention | ratio (Least Squares Mean) | |||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Week 8, Hour 1 | Week 8, Hour 2 | Week 8, Hour 3 | Week 8, Hour 4 | Week 8, Hour 5 | Week 8, Hour 6 | Week 8, Hour 7 | Week 8, Hour 8 | Week 8, Hour 9 | Week 8, Hour 10 | Week 8, Hour 11 | Week 8, Hour 12 | Week 8, Hour 13 | Week 8, Hour 14 | Week 8, Hour 15 | Week 8, Hour 16 | Week 8, Hour 17 | Week 8, Hour 18 | Week 8, Hour 19 | Week 8, Hour 20 | Week 8, Hour 21 | Week 8, Hour 22 | Week 8, Hour 23 | Week 8, Hour 24 | |
Core Period: Eplerenone 50 mg BID | -5.33 | -5.90 | -5.89 | -5.12 | -7.22 | -7.91 | -8.70 | -8.06 | -7.46 | -7.35 | -5.75 | -6.25 | -8.81 | -10.91 | -12.04 | -16.68 | -19.59 | -18.55 | -15.49 | -16.09 | -15.34 | -12.47 | -9.02 | -8.90 |
Core Period: LCI699 0.25 mg QD | -0.54 | -1.59 | -2.11 | -2.06 | -4.29 | -4.21 | -4.95 | -5.28 | -3.98 | -3.69 | -2.47 | -5.19 | -6.45 | -7.37 | -10.61 | -11.71 | -13.71 | -14.49 | -13.78 | -13.92 | -14.33 | -13.46 | -7.88 | -3.16 |
Core Period: LCI699 0.5 mg BID | -1.42 | -0.57 | 0.91 | 1.50 | -1.70 | -1.02 | -0.76 | -3.02 | -1.87 | -1.73 | -1.74 | -3.92 | -4.05 | -6.12 | -9.78 | -13.03 | -13.72 | -15.60 | -15.93 | -15.47 | -13.63 | -10.55 | -6.73 | -3.76 |
Core Period: LCI699 0.5 mg QD | 0.09 | 0.15 | -1.53 | -1.18 | -3.09 | -3.12 | -2.10 | -4.69 | -1.59 | -0.30 | -0.43 | 0.73 | -2.30 | -5.68 | -8.28 | -10.01 | -11.96 | -14.37 | -13.08 | -13.22 | -10.06 | -8.35 | -6.23 | -0.64 |
Core Period: LCI699 1.0 mg QD | -4.51 | -3.56 | -4.86 | -4.15 | -3.47 | -5.88 | -5.40 | -5.30 | -4.78 | -3.40 | -4.22 | -4.35 | -7.25 | -9.33 | -11.26 | -12.63 | -15.46 | -14.54 | -12.85 | -12.54 | -12.78 | -7.52 | -5.77 | -3.45 |
Core Period: Placebo | 8.23 | 6.48 | 4.60 | 4.68 | 2.78 | 1.42 | 2.25 | 3.76 | 2.39 | 2.54 | 3.51 | 4.69 | 3.20 | 0.75 | 0.02 | -0.33 | -3.03 | -6.35 | -6.98 | -6.53 | -3.89 | -0.94 | 2.18 | 0.70 |
Arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the American Heart Association guidelines using a calibrated standard aneroid or mercury sphygmomanometer or a calibrated standard sphygmomanometer. The change in the MSDBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from Baseline in MSDBP was analyzed using an ANCOVA with treatment and country as factors and Baseline MSDBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 8
Intervention | mmHg (Mean) |
---|---|
LCI699 0.25 mg BID | -4.5 |
LCI699 1 mg QD | -6.0 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | -6.1 |
Eplerenone 50 mg BID | -7.7 |
Placebo | -4.8 |
Arterial blood pressure (BP) determinations were made after the participant was in the sitting position for 5 minutes according to the American Heart Association guidelines using a calibrated standard aneroid or mercury sphygmomanometer or a calibrated standard sphygmomanometer. The change in the MSSBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from Baseline in MSSBP was analyzed using an analysis of covariance model (ANCOVA) with treatment and country as factors and Baseline MSSBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 8
Intervention | mmHg (Mean) |
---|---|
LCI699 0.25 mg BID | -11.4 |
LCI699 1 mg QD | -13.1 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | -12.5 |
Eplerenone 50 mg BID | -18.7 |
Placebo | -8.8 |
Arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the American Heart Association guidelines using a calibrated standard aneroid or mercury sphygmomanometer or a calibrated standard sphygmomanometer. The change in the MSDBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from Baseline in MSDBP was analyzed using an ANCOVA with treatment and country as factors and Baseline MSDBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 8
Intervention | mmHg (Mean) |
---|---|
LCI699 0.25 mg BID | -4.5 |
LCI699 1 mg QD | -6.0 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | -6.1 |
Arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the American Heart Association guidelines using a calibrated standard aneroid or mercury sphygmomanometer or a calibrated standard sphygmomanometer. The change in the MSSBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from Baseline in MSSBP was analyzed using an ANCOVA with treatment and country as factors and Baseline MSSBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 8
Intervention | mmHg (Mean) |
---|---|
LCI699 0.25 mg BID | -11.4 |
LCI699 1 mg QD | -13.1 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | -12.5 |
Serum cortisol concentrations at 1 hour after injection were measured to assess the maximum stimulated cortisol level achieved. Potential adrenal suppression was indicated if the serum cortisol concentration was <500 nanomoles per liter (nmol/L) at 1 hour after the injection. (NCT00817635)
Timeframe: 1-hour post-dose at Week 8
Intervention | Participants (Count of Participants) |
---|---|
LCI699 0.25 mg BID | 0 |
LCI699 1 mg QD | 1 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | 4 |
Eplerenone 50 mg BID | 0 |
Placebo | 0 |
Percent change from Baseline was analyzed by ANCOVA model using active renin values measured at Baseline and Week 8 LOCF, with treatment and country as factors and Baseline value as the covariate. Negative percent change from Baseline shows improvement. (NCT00817635)
Timeframe: Baseline, Week 8
Intervention | percent change in ARC (Geometric Least Squares Mean) |
---|---|
LCI699 0.25 mg BID | 73.1 |
LCI699 1 mg QD | 72.8 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | 156.4 |
Eplerenone 50 mg BID | 430.6 |
Percent change from Baseline was analyzed by ANCOVA model using plasma renin values measured at Baseline and Week 8 LOCF, with treatment and country as factors and Baseline value as the covariate. Negative percent change from Baseline shows improvement. (NCT00817635)
Timeframe: Baseline, Week 8
Intervention | percent change in PRA (Geometric Least Squares Mean) |
---|---|
LCI699 0.25 mg BID | 41.6 |
LCI699 1 mg QD | 74.3 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | 107.7 |
Eplerenone 50 mg BID | 414.1 |
Percent change from Baseline was analyzed by ANCOVA model using percent ratio of PA to PRA values measured at Baseline and Week 8 LOCF, with treatment and country as factors and Baseline value as the covariate. Negative percent change from Baseline shows improvement. (NCT00817635)
Timeframe: Baseline, Week 8
Intervention | percent change in ratio of PA to PRA (Geometric Least Squares Mean) |
---|---|
LCI699 0.25 mg BID | -46.7 |
LCI699 1 mg QD | -50.0 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | -78.3 |
Eplerenone 50 mg BID | -57.1 |
Percent change from Baseline was analyzed by ANCOVA model using PA values measured at Baseline and Week 8 LOCF, with treatment and country as factors and Baseline value as the covariate. Negative percent change from Baseline shows improvement. (NCT00817635)
Timeframe: Baseline, Week 8
Intervention | percent change in aldosterone (Geometric Least Squares Mean) |
---|---|
LCI699 0.25 mg BID | -22.3 |
LCI699 1 mg QD | -30.4 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | -53.1 |
Eplerenone 50 mg BID | 115.0 |
An ABPM measured a participant's blood pressure over a 24-hour period including daytime and nighttime readings using an automated validated monitoring device from Baseline to Week 4. The 24-hour DBP was calculated by taking the mean of all ambulatory diastolic blood pressure readings for the 24-hour period. The change from Baseline in DBP was analyzed using an ANCOVA with treatment and country as factors and Baseline MSDBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 4
Intervention | mmHg (Mean) | ||
---|---|---|---|
24-hour Mean DBP | Daytime Mean DBP | Nighttime Mean DBP | |
LCI699 0.5 mg BID | -2.5 | -2.6 | -2.8 |
LCI699 1 mg QD | -4.3 | -3.9 | -4.5 |
An ABPM measured a participant's blood pressure over a 24-hour period including daytime and nighttime readings, using an automated validated monitoring device from Baseline to Week 8. The 24-hour DBP was calculated by taking the mean of all ambulatory diastolic blood pressure readings for the 24-hour period. The change from Baseline in DBP was analyzed using an ANCOVA with treatment and country as factors and Baseline MSDBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 8
Intervention | mmHg (Mean) | ||
---|---|---|---|
24-hour Mean DBP | Daytime Mean DBP | Nighttime Mean DBP | |
Eplerenone 50 mg BID | -9.6 | -9.5 | -9.6 |
LCI699 0.25 mg BID | 1.0 | 0.6 | 1.9 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | -3.7 | -3.4 | -4.6 |
LCI699 1 mg QD | -3.4 | -3.6 | -2.5 |
Placebo | -0.2 | -0.8 | 1.2 |
An ABPM measured a participant's blood pressure over a 24-hour period including daytime and nighttime readings using an automated validated monitoring device from Baseline to Week 4. The 24-hour SBP was calculated by taking the mean of all ambulatory systolic blood pressure readings for the 24-hour period. The change from Baseline in SBP was analyzed using an ANCOVA with treatment and country as factors and Baseline MSDBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 4
Intervention | mmHg (Mean) | ||
---|---|---|---|
24-hour Mean SBP | Daytime Mean SBP | Nighttime Mean SBP | |
LCI699 0.5 mg BID | -4.7 | -5.3 | -4.5 |
LCI699 1 mg QD | -7.8 | -8.1 | -6.8 |
An ABPM measured a participant's blood pressure over a 24-hour period including daytime and nighttime readings, using an automated validated monitoring device from Baseline to Week 8. The 24-hour SBP was calculated by taking the mean of all ambulatory systolic blood pressure readings for the 24-hour period. The change from Baseline in SBP was analyzed using ANCOVA with treatment and country as factors and Baseline MSSBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 8
Intervention | mmHg (Mean) | ||
---|---|---|---|
24-hour Mean SBP | Daytime Mean SBP | Nighttime Mean SBP | |
Eplerenone 50 mg BID | -15.7 | -15.7 | -15.4 |
LCI699 0.25 mg BID | -4.4 | -4.9 | -3.2 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | -6.3 | -6.3 | -7.0 |
LCI699 1 mg QD | -5.7 | -6.0 | -4.8 |
Placebo | -1.0 | -1.6 | 0.4 |
An AE was an adverse medical event which occurs in a participant of the study and which is not necessarily in a causal relationship with the treatment the participant receives. SAEs were AEs leading to death, are life-threatening, require hospitalizations or prolongation of hospitalizations, represent an innate malformation or a congenital abnormality. Hyperkalemia was defined as potassium level >5.5 millimoles per liter (mmol/L). It is the medical term that describes a potassium level that's higher than normal. Hyponatremia was defined as sodium level <135 mmol/L. It is the medical term that describes a sodium level that's lesser than normal. (NCT00817635)
Timeframe: AEs, Hyperkalemia, and Hyponatremia: From start of the study drug treatment up to 10 weeks; SAE: From signing of the informed consent up to 10 weeks
Intervention | Participants (Count of Participants) | |||||
---|---|---|---|---|---|---|
AE(s) | SAE(s) | Hyperkalemia [potassium level >5.5 mmol/L] | Hyperkalemia [potassium level ≥6.0 mmol/L] | Hyponatremia [sodium level <130 and ≥125 mmol/L] | Hyponatremia [sodium level <135 mmol/L and ≥130mmol/L] | |
Eplerenone 50 mg BID | 13 | 1 | 0 | 0 | 1 | 3 |
LCI699 0.25 mg BID | 15 | 0 | 2 | 2 | 0 | 3 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | 8 | 0 | 0 | 0 | 0 | 7 |
LCI699 1 mg QD | 15 | 0 | 0 | 0 | 0 | 2 |
Placebo | 16 | 0 | 1 | 0 | 0 | 2 |
MSDBP response was defined as the percentage of participants with a MSDBP <90 mmHg or a >=10 mmHg reduction from baseline. MSDBP control was defined as the percentage of participants with a MSDBP <90 mmHg for non-diabetic participants and <80mHg for diabetic participants. (NCT00817635)
Timeframe: Week 8
Intervention | percentage of participants (Number) | |
---|---|---|
MSDBP Response | MSDBP Control | |
Eplerenone 50 mg BID | 71.9 | 56.3 |
LCI699 0.25 mg BID | 67.7 | 54.8 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | 71.0 | 58.1 |
LCI699 1 mg QD | 73.1 | 65.4 |
Placebo | 57.6 | 54.5 |
MSSBP response was defined as the percentage of participants with a MSSBP <140 mmHg or a >=20 mmHg reduction from baseline reduction from baseline. MSSBP control was defined as the percentage of participants with a MSSBP <140 mmHg for non-diabetic participants and <130mHg for diabetic participants. (NCT00817635)
Timeframe: Week 8
Intervention | percentage of participants (Number) | |
---|---|---|
MSSBP Response | MSSBP Control | |
Eplerenone 50 mg BID | 65.6 | 53.1 |
LCI699 0.25 mg BID | 54.8 | 51.6 |
LCI699 0.5 mg Followed by LCI699 1 mg BID | 41.9 | 32.3 |
LCI699 1 mg QD | 57.7 | 50.0 |
Placebo | 42.4 | 36.4 |
Insulin resistance was measured using the 75 G glucose tolerance test. Participants ingested 75 grams of glucose in 300-400 mL of water over 5 minutes. Blood samples were taken before ingesting glucose and then every 30 minutes for 120 minutes. HOMA-IR was calculated using the Insulin and glucose levels obtained. A negative change (decrease in insulin resistance) indicates improvement. (NCT01406015)
Timeframe: Baseline and Week 6 (Prior to ingesting glucose and every 30 minutes for 120 minutes)
Intervention | IR index (Mean) | |
---|---|---|
Baseline | Change from Baseline at Week 6 | |
Placebo | 3.4 | 0.1 |
Spironolactone | 2.7 | 0.1 |
Insulin sensitivity was measured using the 75 gram (G) glucose tolerance test. Participants ingested 75 grams of glucose in 300-400 milliliters (mL) of water over 5 minutes. Blood samples were taken before ingesting glucose and then every 30 minutes for 120 minutes. Insulin sensitivity index was calculated by Matsuda and Defronzo's formula using the values obtained. A positive change from Baseline (increase in insulin sensitivity) indicates improvement. (NCT01406015)
Timeframe: Baseline and Week 6 (Prior to ingesting glucose and every 30 minutes for 120 minutes)
Intervention | IS index (Mean) | |
---|---|---|
Baseline | Change from Baseline at Week 6 | |
Placebo | 4.6 | -1.1 |
Spironolactone | 3.7 | -0.1 |
Renal plasma blood flow was determined by clearance of para-aminohippurate (PAH). A loading dose of PAH (8 mg/kg) was given intravenously followed by a 1 hour constant infusion of PAH at a rate of 12 mg/minute (min). Plasma samples were obtained at Baseline and at 50 and 60 minutes. PAH clearance was calculated from the plasma levels and infusion rates and reported in millimeters (mL)/minute (min). A positive change from Baseline indicates improvement. (NCT01406015)
Timeframe: Baseline and Week 6 (Prior to PAH infusion and at 50 and 60 minutes post PAH infusion)
Intervention | mL/min (Mean) | |
---|---|---|
Baseline | Change from Baseline at Week 6 | |
Placebo | 521 | -5.2 |
Spironolactone | 488 | -2.3 |
Ultrasonography of the brachial artery was performed to evaluate endothelial function by flow mediated dilatation (FMD) studies. A blood pressure cuff was placed on the participant's upper arm and was compressed for 5 minutes. After release of compression, brachial artery diameter and blood flow velocity were measured. FMD was expressed as the percentage change in brachial artery diameter. A positive change from Baseline indicates improvement. (NCT01406015)
Timeframe: Baseline and Week 6
Intervention | percent dilalation (Mean) | |
---|---|---|
Baseline | Change from Baseline at Week 6 | |
Placebo | 10.2 | -2.0 |
Spironolactone | 9.6 | -1.2 |
Acute Insulin response during Hyperglycemic clamp (delta insulin uU/mL, t=0-10) (NCT00732160)
Timeframe: 3 hours
Intervention | uU/mL (Mean) |
---|---|
Vehicle, HS | 48.9 |
Vehicle, LS | 37.6 |
Aldosterone, HS | 51.8 |
Aldosterone, LS | 34.4 |
Insulin sensitivity index (ISI) was calculated by dividing the average glucose infusion rate (mg glucose infusion/kg body weight/min) by the average insulin concentration (uU/mL) from 90 to 120 minutes. This was multiplied by 100 (thus, x100 in units description), per reporting convention in literature. (NCT00732160)
Timeframe: 3 hours
Intervention | mg/kg/min per uU/mL*100 (Mean) |
---|---|
Vehicle, HS | 25.2 |
Vehicle, LS | 24.8 |
Aldosterone, HS | 23.4 |
Aldosterone, LS | 24.7 |
Annual percent change in 24 hour urine albumin, centrally processed. Data from multiple years were analyzed with the primary focus on the change over time for the measure (from the slope of the model). The measure presented is the average annual percent change across the 8 years. (NCT01885559)
Timeframe: up to 8 years (annually assessed)
Intervention | annual percent change (Mean) |
---|---|
ACE-I + Placebo | 7.5 |
ACE-I + ARB | 7.3 |
Annual percent change in urinary aldosterone, centrally processed measure. Data from multiple years were analyzed with the primary focus on the change over time for the measure (from the slope for time from the model). The measure presented is the average annual percent change across the 8 years. (NCT01885559)
Timeframe: up at 8 years (annually assessed)
Intervention | annual percent change (Mean) |
---|---|
ACE-I + Placebo | -8.8 |
ACE-I + ARB | -10.2 |
Report of back or flank pain since the last visit (yes or no) (NCT01885559)
Timeframe: 48 months
Intervention | percentage of participants at 48 months (Number) |
---|---|
ACE-I + Placebo | 43 |
ACE-I + ARB | 46 |
Cause-specific hospitalizations (cardiovascular) (NCT01885559)
Timeframe: up to 8 years
Intervention | events (Number) |
---|---|
ACE-I + Placebo | 29 |
ACE-I + ARB | 16 |
Hospitalization for any cause (NCT01885559)
Timeframe: up to 8 years
Intervention | events (Number) |
---|---|
ACE-I + Placebo | 173 |
ACE-I + ARB | 136 |
(NCT01885559)
Timeframe: Patients followed for 5-8 years with average of 6.5 years follow up
Intervention | participants (Number) |
---|---|
ACE-I + Placebo | 116 |
ACE-I + ARB | 115 |
Short Form-36 Quality of Life Mental Component Summary ranges from 0 (worst possible outcome) to 100 (best possible outcome). Data from multiple years were analyzed with the primary focus on the change over time for the measure (from the slope for time from the model). The measure presented is the average annual change across the 8 years. (NCT01885559)
Timeframe: up to 8 years (annually assessed)
Intervention | units on a scale per year (Mean) |
---|---|
ACE-I + Placebo | -0.031 |
ACE-I + ARB | -0.079 |
Short Form-36 Quality of Life Physical Component Summary ranges from 0 (worst possible outcome) to 100 (best possible outcome). Data from multiple years were analyzed with the primary focus on the change over time for the measure (from the slope for time from the model). The measure presented is the average annual change across the 8 years. (NCT01885559)
Timeframe: up to 8 years (annually assessed)
Intervention | units on a scale per year (Mean) |
---|---|
ACE-I + Placebo | -0.64 |
ACE-I + ARB | -0.68 |
Baseline 24-hour average SBP was assessed using 24-hour ambulatory blood pressure monitoring (ABPM). (NCT01096667)
Timeframe: 24 hours
Intervention | mmHg (Mean) |
---|---|
Placebo | 136.11 |
Ertugliflozin 1 mg | 133.13 |
Ertugliflozin 5 mg | 135.08 |
Ertugliflozin 25 mg | 135.59 |
HCTZ 12.5mg | 139.55 |
Urinary glucose excetion was corrected for a duration of 24 hours (with appropriate duration of collection defined as >20 hours and <28 hours). (NCT01096667)
Timeframe: 24 hours
Intervention | grams/day (Mean) |
---|---|
Placebo | 13.35 |
Ertugliflozin 1 mg | 9.97 |
Ertugliflozin 5 mg | 8.04 |
Ertugliflozin 25 mg | 17.56 |
HCTZ 12.5mg | 6.96 |
For FPG, blood was drawn after an overnight fast of at least 8 hours (except water). (NCT01096667)
Timeframe: Baseline
Intervention | mg/dL (Mean) |
---|---|
Placebo | 169.47 |
Ertugliflozin 1 mg | 158.38 |
Ertugliflozin 5 mg | 158.29 |
Ertugliflozin 25 mg | 172.03 |
HCTZ 12.5mg | 156.87 |
Trough DBP was measured using an automated blood pressure device with the participant in a seated position for at least 5 minutes before and while the blood pressure measure is obtained. Three measurements of blood pressure were taken at least 2-minutes apart. Baseline trough DBP is calculated as the mean of triplicate (3) trough DBP measures. (NCT01096667)
Timeframe: Baseline
Intervention | mmHg (Mean) |
---|---|
Placebo | 84.89 |
Ertugliflozin 1 mg | 83.08 |
Ertugliflozin 5 mg | 83.79 |
Ertugliflozin 25 mg | 83.89 |
HCTZ 12.5mg | 84.72 |
Trough heart rate was measured using an automated blood pressure device with the participant in a seated position for at least 5 minutes before and while the heart rate measure was obtained. Three measurements of heart rate were taken at least 2-minutes apart. Baseline trough heart rate is calculated as the mean of triplicate (3) trough heart rate measures. (NCT01096667)
Timeframe: Baseline
Intervention | beats per minute (Mean) |
---|---|
Placebo | 77.07 |
Ertugliflozin 1 mg | 78.73 |
Ertugliflozin 5 mg | 77.30 |
Ertugliflozin 25 mg | 75.63 |
HCTZ 12.5mg | 77.97 |
Trough SBP was measured using an automated blood pressure device with the participant in a seated position for at least 5 minutes before and while the blood pressure measure is obtained. Three measurements of blood pressure were taken at least 2-minutes apart. Baseline trough SBP is calculated as the mean of triplicate (3) trough SBP measures. (NCT01096667)
Timeframe: Baseline
Intervention | mmHg (Mean) |
---|---|
Placebo | 135.17 |
Ertugliflozin 1 mg | 134.23 |
Ertugliflozin 5 mg | 137.31 |
Ertugliflozin 25 mg | 135.25 |
HCTZ 12.5mg | 138.07 |
For FPG, blood was drawn after an overnight fast of at least 8 hours (except water). (NCT01096667)
Timeframe: Baseline and Week 2
Intervention | mg/dL (Least Squares Mean) |
---|---|
Placebo | -5.44 |
Ertugliflozin 1 mg | -10.98 |
Ertugliflozin 5 mg | -22.45 |
Ertugliflozin 25 mg | -32.03 |
HCTZ 12.5mg | 3.21 |
For FPG, blood was drawn after an overnight fast of at least 8 hours (except water). (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | mg/dL (Least Squares Mean) |
---|---|
Placebo | 4.39 |
Ertugliflozin 1 mg | -13.70 |
Ertugliflozin 5 mg | -30.41 |
Ertugliflozin 25 mg | -31.03 |
HCTZ 12.5mg | 3.79 |
Trough DBP was measured using an automated blood pressure device with the participant in a seated position for at least 5 minutes before and while the blood pressure measure is obtained. Three measurements of blood pressure were taken at least 2-minutes apart. The change from baseline at Week 4 is the difference between the baseline and Week 4 assessments. (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | mmHg (Least Squares Mean) |
---|---|
Placebo | 0.30 |
Ertugliflozin 1 mg | -0.90 |
Ertugliflozin 5 mg | -0.75 |
Ertugliflozin 25 mg | -2.71 |
HCTZ 12.5mg | -2.54 |
Trough heart rate was measured using an automated blood pressure device with the participant in a seated position for at least 5 minutes before and while the heart rate measure was obtained. Three measurements of heart rate were taken at least 2-minutes apart. The change from baseline at Week 4 is the difference between the baseline and Week 4 assessments. (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | beats per minute (Least Squares Mean) |
---|---|
Placebo | 2.34 |
Ertugliflozin 1 mg | -1.86 |
Ertugliflozin 5 mg | 1.22 |
Ertugliflozin 25 mg | -1.51 |
HCTZ 12.5mg | -0.99 |
Trough SBP was measured using an automated blood pressure device with the participant in a seated position for at least 5 minutes before and while the blood pressure measure is obtained. Three measurements of blood pressure were taken at least 2-minutes apart. The change from baseline at Week 4 is the difference between the baseline and Week 4 assessments. (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | mmHg (Least Squares Mean) |
---|---|
Placebo | 1.24 |
Ertugliflozin 1 mg | -2.77 |
Ertugliflozin 5 mg | -5.92 |
Ertugliflozin 25 mg | -4.96 |
HCTZ 12.5mg | -3.13 |
Change from baseline on 24-hour average DBP at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | mmHg (Least Squares Mean) |
---|---|
Placebo | 0.77 |
Ertugliflozin 1 mg | -1.89 |
Ertugliflozin 5 mg | -2.34 |
Ertugliflozin 25 mg | -1.50 |
HCTZ 12.5mg | -1.42 |
Change from baseline in 24-hour average heart rate at Week 4 using 24 hour ABPM. (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | Beats per minute (Least Squares Mean) |
---|---|
Placebo | 1.00 |
Ertugliflozin 1 mg | -1.22 |
Ertugliflozin 5 mg | 1.07 |
Ertugliflozin 25 mg | -1.39 |
HCTZ 12.5mg | -0.56 |
Change from baseline on 24-hour average SBP at Week 4 assessed using 24-hour ABPM. In the case of missing data, last observation carried forward (LOCF). (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | mmHg (Least Squares Mean) |
---|---|
Placebo | 0.26 |
Ertugliflozin 1 mg | -2.71 |
Ertugliflozin 5 mg | -3.73 |
Ertugliflozin 25 mg | -3.42 |
HCTZ 12.5mg | -2.95 |
Urinary glucose excetion was corrected for a duration of 24 hours (with appropriate duration of collection defined as >20 hours and <28 hours). In the case of missing data, LOCF. (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | grams/day (Least Squares Mean) |
---|---|
Placebo | 4.15 |
Ertugliflozin 1 mg | 46.33 |
Ertugliflozin 5 mg | 64.54 |
Ertugliflozin 25 mg | 74.49 |
HCTZ 12.5mg | -0.48 |
Change from baseline on daytime average DBP at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. Daytime was defined as 0600 to 2159 hours, inclusive, local time. (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | mmHg (Least Squares Mean) |
---|---|
Placebo | 0.87 |
Ertugliflozin 1 mg | -2.12 |
Ertugliflozin 5 mg | -1.88 |
Ertugliflozin 25 mg | -1.77 |
HCTZ 12.5mg | -1.69 |
Change from baseline in daytime average heart rate at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. Daytime was defined as 0600 to 2159 hours, inclusive, local time. (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | Beats per minute (Least Squares Mean) |
---|---|
Placebo | 1.58 |
Ertugliflozin 1 mg | -1.80 |
Ertugliflozin 5 mg | 1.10 |
Ertugliflozin 25 mg | -1.07 |
HCTZ 12.5mg | -0.06 |
Change from baseline on daytime average SBP at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. Daytime was defined as 0600 to 2159 hours, inclusive, local time. (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | mmHg (Least Squares Mean) |
---|---|
Placebo | 0.82 |
Ertugliflozin 1 mg | -2.88 |
Ertugliflozin 5 mg | -3.61 |
Ertugliflozin 25 mg | -4.17 |
HCTZ 12.5mg | -3.10 |
Change from baseline on nighttime average DBP at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. Nighttime was defined as 2200 to 0559 hours, inclusive, local time. (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | mmHg (Least Squares Mean) |
---|---|
Placebo | 1.02 |
Ertugliflozin 1 mg | -1.48 |
Ertugliflozin 5 mg | -2.52 |
Ertugliflozin 25 mg | -0.84 |
HCTZ 12.5mg | -0.55 |
Change from baseline in 24-hour nighttime average heart rate at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. Nighttime was defined as 2200 to 0559 hours, inclusive, local time. (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | Beats per minute (Least Squares Mean) |
---|---|
Placebo | -0.18 |
Ertugliflozin 1 mg | -0.15 |
Ertugliflozin 5 mg | 1.43 |
Ertugliflozin 25 mg | -1.99 |
HCTZ 12.5mg | -1.24 |
Change from baseline on nighttime average SBP at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. Nighttime was defined as 2200 to 0559 hours, inclusive, local time. (NCT01096667)
Timeframe: Baseline and Week 4
Intervention | mmHg (Least Squares Mean) |
---|---|
Placebo | -0.29 |
Ertugliflozin 1 mg | -2.48 |
Ertugliflozin 5 mg | -3.47 |
Ertugliflozin 25 mg | -2.31 |
HCTZ 12.5mg | -2.30 |
An adverse event is defined as any untoward medical occurrence in a clinical investigation participant administered a product or medical device; the event need not necessarily have a causal relationship with the treatment or usage. The table below includes all data collected since first dose of study drug. Discontinuation of study drug due to an AE includes temporary and permanent discontinuation of study drug due to an AE. (NCT01096667)
Timeframe: Up to 28 days (treatment period)
Intervention | Participants (Number) |
---|---|
Placebo | 0 |
Ertugliflozin 1 mg | 0 |
Ertugliflozin 5 mg | 0 |
Ertugliflozin 25 mg | 1 |
HCTZ 12.5mg | 0 |
An adverse event is defined as any untoward medical occurrence in a clinical investigation participant administered a product or medical device; the event need not necessarily have a causal relationship with the treatment or usage. The table below includes all data collected since first dose of study drug. (NCT01096667)
Timeframe: Up to 63 days (including run-in, treatment period, and follow-up)
Intervention | Participants (Number) |
---|---|
Placebo | 9 |
Ertugliflozin 1 mg | 8 |
Ertugliflozin 5 mg | 15 |
Ertugliflozin 25 mg | 12 |
HCTZ 12.5mg | 10 |
Baseline 24-hour average DBP was assessed using 24-hour ABPM. Daytime was defined as 0600 to 2159 hours, inclusive, local time. Nighttime was defined as 2200 to 0559 hours, inclusive, local time. (NCT01096667)
Timeframe: up to 24 hours
Intervention | mmHg (Mean) | ||
---|---|---|---|
24-hr | Daytime | Nighttime | |
Ertugliflozin 1 mg | 78.67 | 81.77 | 72.05 |
Ertugliflozin 25 mg | 80.36 | 83.59 | 73.28 |
Ertugliflozin 5 mg | 80.18 | 83.47 | 73.05 |
HCTZ 12.5mg | 82.66 | 85.87 | 75.76 |
Placebo | 81.89 | 85.32 | 74.24 |
Baseline 24-hour average heart rate was assessed using 24-hour ABPM. Daytime was defined as 0600 to 2159 hours, inclusive, local time. Nighttime was defined as 2200 to 0559 hours, inclusive, local time. (NCT01096667)
Timeframe: up to 24 hours
Intervention | beats per minute (Mean) | ||
---|---|---|---|
24-hr | Daytime | Nighttime | |
Ertugliflozin 1 mg | 80.74 | 83.74 | 74.44 |
Ertugliflozin 25 mg | 79.41 | 82.18 | 73.49 |
Ertugliflozin 5 mg | 79.68 | 82.71 | 73.16 |
HCTZ 12.5mg | 79.08 | 81.95 | 73.03 |
Placebo | 81.11 | 84.43 | 74.05 |
Daytime was defined as 0600 to 2159 hours, inclusive, local time. Nighttime was defined as 2200 to 0559 hours, inclusive, local time. (NCT01096667)
Timeframe: Daytime: 16 hours; Nighttime: 8 hours
Intervention | mmHg (Mean) | |
---|---|---|
Daytime | Nighttime | |
Ertugliflozin 1 mg | 136.85 | 125.15 |
Ertugliflozin 25 mg | 139.56 | 127.13 |
Ertugliflozin 5 mg | 138.89 | 126.37 |
HCTZ 12.5mg | 143.32 | 131.68 |
Placebo | 139.95 | 127.54 |
"24-h Systolic Blood Pressure is the average of all 24-h Ambulatory Systolic Blood Pressure recordings. The Wake Period Systolic Blood Pressure is the average of all Systolic Blood Pressures recorded every 15 minutes during the wake period. The Sleep Period Systolic Blood pressure is the average of all Systolic Blood Pressures recorded every 30 minutes during the sleep period.~24-h Diastolic Blood Pressure is the average of all 24-h Ambulatory Diastolic Blood Pressure recordings. The Wake Period Diastolic Blood Pressure is the average of all Diastolic Blood Pressures recorded every 15 minutes during the wake period. The Sleep Period Diastolic Blood pressure is the average of all Diastolic Blood Pressures recorded every 30 minutes during the sleep period." (NCT02710071)
Timeframe: At the end of 2 weeks of placebo therapy, at the end of 6 weeks of Nebivolol therapy and at the end of 6 weeks of hydrochlorothiazide therapy.
Intervention | mmHg (Mean) | |||||
---|---|---|---|---|---|---|
24-h systolic blood pressure | 24-h diastolic blood pressure | Wake systolic blood pressure | Wake diastolic blood pressure | Sleep systolic blood pressure | Sleep diastolic blood pressure | |
Hydrochlorothiazide | 133 | 80 | 138 | 85 | 127 | 75 |
Nebivolol | 130 | 77 | 135 | 81 | 123 | 71 |
Placebo | 137 | 82 | 141 | 86 | 129 | 76 |
Brachial Artery Flow Mediated Dilation is upper arm brachial artery dilation during the 3 minutes forearm reactive hyperemia following the release of the 5-minute forearm cuff occlusion. (NCT02699125)
Timeframe: At the end of 2 weeks of placebo therapy, at the end of 6 weeks of guanfacine therapy and at the end of 6 weeks of hydrochlorothiazide therapy.
Intervention | percentage of the preoclussion diameter (Mean) |
---|---|
Placebo | 4.5 |
Guanfacine | 8.4 |
Hydrochlorothiazide | 4.9 |
"The primary outcome measure is ambulatory systolic and diastolic blood pressure recorded once every 15 minutes during the day and once every 30 minutes during the sleep. The Outcome Measure Data Table present primary outcome as 24-h, Wake and Sleep Period Systolic and Diastolic Blood Pressure after each of the following three interventions: Placebo, Guanfacine and Hydrochlorothiazide." (NCT02699125)
Timeframe: At the end of 2 weeks of placebo therapy, at the end of 6 weeks of guanfacine therapy and at the end of 6 weeks of hydrochlorothiazide therapy.
Intervention | mmHg (Mean) | |||||
---|---|---|---|---|---|---|
24-h systolic blood pressure | 24-h diastolic blood pressure | Wake systolic blood pressure | Wake diastolic blood pressure | Sleep systolic blood pressure | Sleep diastolic blood pressure | |
Guanfacine | 133 | 81 | 137 | 84 | 124 | 73 |
Hydrochlorothyazide | 136 | 83 | 139 | 86 | 130 | 76 |
Placebo | 143 | 87 | 147 | 91 | 136 | 80 |
Left ventricular mass index (LVMI) was measured by magnetic resonance imaging (MRI). An increase in LVMI indicates hypertrophy of the left ventricle. This could be a normal reversible response to cardiovascular conditioning (athletic heart) or an abnormal irreversible response to chronically increased volume load (preload) or increased pressure load (afterload). Thickening of the ventricular muscle results in increased left ventricular pressure, increased end-systolic volume, and decreased end-diastolic volume, causing an overall reduction in cardiac output. (NCT00219141)
Timeframe: Baseline to end of study (Week 36)
Intervention | g/m^2 (Least Squares Mean) |
---|---|
Aliskiren 300 mg | -5.51 |
Losartan 100 mg | -4.81 |
Aliskiren/Losartan 300/100 mg | -5.61 |
(NCT00219141)
Timeframe: Baseline to end of study (Week 36)
Intervention | mm * ms (Mean) |
---|---|
Aliskiren 300 mg | -104.97 |
Losartan 100 mg | -150.31 |
Aliskiren/Losartan 300/100 mg | -130.65 |
(NCT00219141)
Timeframe: Baseline to end of study (Week 36)
Intervention | mm (Mean) |
---|---|
Aliskiren 300 mg | -0.71 |
Losartan 100 mg | -0.64 |
Aliskiren/Losartan 300/100 mg | -0.86 |
(NCT00219141)
Timeframe: Baseline to end of study (Week 36)
Intervention | mm (Mean) |
---|---|
Aliskiren 300 mg | -0.95 |
Losartan 100 mg | -1.20 |
Aliskiren/Losartan 300/100 mg | -1.17 |
(NCT00219141)
Timeframe: Baseline to end of study (Week 36)
Intervention | percent (Mean) |
---|---|
Aliskiren 300 mg | 0.62 |
Losartan 100 mg | 2.02 |
Aliskiren/Losartan 300/100 mg | 1.92 |
(NCT00219141)
Timeframe: Baseline to end of study (Week 36)
Intervention | g (Mean) |
---|---|
Aliskiren 300 mg | -9.81 |
Losartan 100 mg | -9.92 |
Aliskiren/Losartan 300/100 mg | -12.29 |
(NCT00219141)
Timeframe: Baseline to end of study (Week 36)
Intervention | mL (Mean) |
---|---|
Aliskiren 300 mg | -7.05 |
Losartan 100 mg | -4.52 |
Aliskiren/Losartan 300/100 mg | -7.03 |
(NCT00219141)
Timeframe: Baseline to end of study (Week 36)
Intervention | mL (Mean) |
---|---|
Aliskiren 300 mg | -3.20 |
Losartan 100 mg | -4.73 |
Aliskiren/Losartan 300/100 mg | -5.14 |
(NCT00219141)
Timeframe: Baseline to end of study (Week 36)
Intervention | mm (Mean) |
---|---|
Aliskiren 300 mg | -0.88 |
Losartan 100 mg | -0.89 |
Aliskiren/Losartan 300/100 mg | -0.90 |
(NCT00219141)
Timeframe: Baseline to end of study (Week 36)
Intervention | g/m^2 (Mean) |
---|---|
Aliskiren 300 mg | -4.87 |
Losartan 100 mg | -4.79 |
Aliskiren/Losartan 300/100 mg | -5.81 |
(NCT00219141)
Timeframe: Baseline to end of study (Week 36)
Intervention | mL (Mean) |
---|---|
Aliskiren 300 mg | -3.89 |
Losartan 100 mg | 0.24 |
Aliskiren/Losartan 300/100 mg | -2.24 |
(NCT00219141)
Timeframe: Baseline to end of study (Week 36)
Intervention | mm (Mean) |
---|---|
Aliskiren 300 mg | -1.07 |
Losartan 100 mg | -0.97 |
Aliskiren/Losartan 300/100 mg | -1.43 |
Two 24-hour ambulatory blood pressure monitoring (ABPM) evaluations were performed, one at baseline and one at the end of the study. For each evaluation, the ABPM device was attached to the non-dominant arm of the patient. A correlation was made between the ABPM device readings and measurements taken with a mercury sphygmomanometer and stethoscope. Following the correlation procedure, blood pressure was measured at study specified intervals. (NCT00219141)
Timeframe: Baseline the end of study (Week 36)
Intervention | mm Hg (Least Squares Mean) | |
---|---|---|
Systolic | Diastolic | |
Aliskiren 300 mg | -2.67 | -1.31 |
Aliskiren/Losartan 300/100 mg | -6.97 | -4.11 |
Losartan 100 mg | -3.81 | -1.92 |
(NCT01062763)
Timeframe: 4 months
Intervention | participants (Number) |
---|---|
Addition of Spironolactone | 4 |
Placebo | 0 |
Change of diastolic blood pressure from baseline to study end at four months. (NCT01062763)
Timeframe: 4 months
Intervention | mm Hg (Mean) |
---|---|
Addition of Spironolactone | -3.9 |
Placebo | -0.3 |
Change of systolic blood pressure from baseline to study end at four months. (NCT01062763)
Timeframe: 4 months
Intervention | mm Hg (Mean) |
---|---|
Addition of Spironolactone | -9.6 |
Placebo | -0.7 |
(NCT01502787)
Timeframe: 12 weeks after initiation of metoprolol
Intervention | mmHg (Mean) |
---|---|
Metoprolol | 114 |
Nebivolol | 113 |
(NCT01502787)
Timeframe: 12 weeks
Intervention | mmHg (Mean) |
---|---|
Initial Treatment With Metoprolol | 101 |
Initial Treatment With Nebivolol | 103 |
(NCT01502787)
Timeframe: 12 weeks after each specified medication
Intervention | ml/min (Mean) |
---|---|
First Intervention Metoprolol: 12 Weeks | 96 |
Second Intervention Nebivolol: 24 Weeks | 105 |
Urine was collected over 24 hours during treatment. The urinary volume was measured and the urine was analyzed for creatinine and catecholamines. Total amounts of creatinine and catecholamines were calculated and the results are expressed as catecholamine:creatinine. (NCT00685919)
Timeframe: Immediately before the 1st dose of Placebo or Carbidopa and ending immediately before the last dose (approximately 24 hours)
Intervention | Micrograms per milligrams (ug/mg) (Mean) |
---|---|
Healthy Participants Who Received Placebo as Treatment A or Treatment B | 0.024 |
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B | 0.283 |
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B | 0.026 |
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B | 0.385 |
Urine was collected over 24 hours during treatment. The urinary volume was measured and the urine was analyzed for creatinine and catecholamines. Total amounts of creatinine and catecholamines were calculated and the results are expressed as catecholamine:creatinine. (NCT00685919)
Timeframe: Immediately before the 1st dose of Placebo or Carbidopa and ending immediately before the last dose (approximately 24 hours)
Intervention | Micrograms per milligrams (ug/mg) (Mean) |
---|---|
Healthy Participants Who Received Placebo as Treatment A or Treatment B | 0.208 |
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B | 0.035 |
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B | 0.24 |
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B | 0.038 |
Urine was collected for 24hr during treatment. Urinary volume was measured and the urine was analyzed for sodium and creatinine concentrations. Total amounts of sodium and creatinine excreted over the 24 hr were calculated and results expressed as ratio of sodium:creatinine. (NCT00685919)
Timeframe: Immediately before the 1st dose of placebo or carbidopa to immediately before the 5th dose (approximately 24 hours)
Intervention | Milliequivalents per gram (mEq/g) (Mean) |
---|---|
Healthy Participants Who Received Placebo as Treatment A or Treatment B | 140 |
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B | 132 |
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B | 137 |
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B | 154 |
Blood samples were collected while resting supine for at least 30 minutes and 2 to 4 hours after lunch. For catecholamine measurements, blood was collected in chilled vacuum tubes with EDTA. Plasma was separated and stored with added reduced glutathione (Amersham International PLC) at -70°C until the assay. Plasma catecholamines were measured by a method that involves batch alumina extraction followed by high-performance liquid chromatography (HPLC) for separation with electrochemical detection and quantification. (NCT00685919)
Timeframe: 8 hours after the last dose of placebo or carbidopa
Intervention | Picograms per milliliter (pg/mL) (Mean) |
---|---|
Healthy Participants Who Received Placebo as Treatment A or Treatment B | 1813 |
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B | 20297 |
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B | 2104 |
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B | 25680 |
Blood samples were collected while resting supine for at least 30 minutes and 2 to 4 hours after lunch. For catecholamine measurements, blood was collected in chilled vacuum tubes with EDTA. Plasma was separated and stored with added reduced glutathione (Amersham International PLC) at -70°C until the assay. Plasma catecholamines were measured by a method that involves batch alumina extraction followed by high-performance liquid chromatography (HPLC) for separation with electrochemical detection and quantification. (NCT00685919)
Timeframe: 8 hours after the last dose of placebo or carbidopa
Intervention | Picograms per milliliter (pg/mL) (Mean) |
---|---|
Healthy Participants Who Received Placebo as Treatment A or Treatment B | 150 |
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B | 181 |
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B | 278 |
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B | 245 |
Blood samples were collected while resting supine for at least 30 minutes and 2 to 4 hours after lunch. Samples were processed and sent to the Vanderbilt Clinical Laboratory for assay. (NCT00685919)
Timeframe: 8 hours after the last dose of placebo or carbidopa
Intervention | Milliequivalents per liter (mEq/L) (Mean) |
---|---|
Healthy Participants Who Received Placebo as Treatment A or Treatment B | 138 |
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B | 138 |
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B | 139 |
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B | 138 |
Blood samples were collected while resting supine for at least 30 minutes and 1 1/2 to 2 hours after breakfast. Samples were processed and sent to the Vanderbilt Clinic Laboratory for assay. (NCT00685919)
Timeframe: 2 hours after the last dose of placebo or carbidopa
Intervention | Nanograms per milliliter per hour (ng/mL (Mean) |
---|---|
Healthy Participants Who Received Placebo as Treatment A or Treatment B | 1.153 |
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B | 1.033 |
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B | 1.544 |
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B | 1.878 |
Systolic blood pressure was measured once using a Dinamap non-invasive oscillometric blood pressure monitor, 2-4 hours after lunch and after at least 30 minutes of resting supine. (NCT00685919)
Timeframe: 8 hours after the last dose of placebo or carbidopa
Intervention | millimeters of mercury (mmHg) (Mean) |
---|---|
Healthy Participants Who Received Placebo as Treatment A or Treatment B | 103 |
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B | 101 |
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B | 102 |
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B | 101 |
(NCT00627861)
Timeframe: all visits (weekly for 12 weeks)
Intervention | mm Hg (Number) | |||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Week 1-Systolic | Week 1-Diastolic | Week 2-Systolic | Week 2-Diastolic | Week 3-Systolic | Week 3-Diastolic | Week 4-Systolic | Week 4-Diastolic | Week 5-Systolic | Week 5-Diastolic | Week 6-Systolic | Week 6-Diastolic | Week 7-Systolic | Week 7-Diastolic | Week 8-Systolic | Week 8-Diastolic | Week 9-Systolic | Week 9 -Diastolic | Week 10-Systolic | Week 10-Diastolic | Week 11-Systolic | Week 11-Diastolic | Week 12-Systolic | Week 12-Diastolic | |
Aliskiren and Metoprolol | 146 | 64 | 144 | 88 | 148 | 90 | 148 | 92 | 156 | 92 | 150 | 84 | 157 | 89 | 147 | 76 | 129 | 94 | 139 | 79 | 170 | 90 | 146 | 78 |
The blood test, plasma renin activity or PRA, is being measured during the visits outlined. (NCT00627861)
Timeframe: screening, 4th, 6th, 7th, 9th, 10th, 11th, 12th weeks
Intervention | ng/mL/h (Number) | |||||||
---|---|---|---|---|---|---|---|---|
Screening | Week 4 | Week 6 | Week 7 | Week 9 | Week 10 | Week 11 | Week 12 | |
Aliskiren and Metoprolol | 2.07 | 1.22 | 0.28 | 0.18 | 0.28 | 0.07 | 0.03 | 0.06 |
(NCT00627861)
Timeframe: 5th, 6th, 7th, 9th, 10th, 11th, 12th weeks
Intervention | pg/mL (Number) | ||||||
---|---|---|---|---|---|---|---|
Week 5 | Week 6 | Week 7 | Week 9 | Week 10 | Week 11 | Week 12 | |
Aliskiren and Metoprolol | 16.5 | 13.5 | 20.5 | 22 | 2.7 | 4.4 | 3.2 |
799 reviews available for aldosterone and Hypertension
Article | Year |
---|---|
Adrenal venous sampling in the diagnostic workup of primary aldosteronism.
Topics: Adrenal Glands; Aldosterone; Blood Specimen Collection; Humans; Hyperaldosteronism; Hypertension; Ma | 2022 |
Diagnosis and treatment of primary aldosteronism.
Topics: Adenoma; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertensio | 2021 |
Effect of diuretics on plasma aldosterone and potassium in primary hypertension: A systematic review and meta-analysis.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Diuretics; Humans; Hypertension; Potassium; Th | 2022 |
[Conn's syndrome-Frequent and still too rarely diagnosed to underdiagnosed].
Topics: Adrenalectomy; Aldosterone; Diabetes Mellitus, Type 2; Humans; Hyperaldosteronism; Hypertension; Ren | 2022 |
Mechanical dependency of the SARS-CoV-2 virus and the renin-angiotensin-aldosterone (RAAS) axis: a possible new threat.
Topics: Aldosterone; Angiotensins; COVID-19; Humans; Hypertension; Peptidyl-Dipeptidase A; Renin; Renin-Angi | 2022 |
Primary Aldosteronism, Aldosterone, and Extracellular Vesicles.
Topics: Aldosterone; Biomarkers; Extracellular Vesicles; Gene Expression Regulation; Humans; Hyperaldosteron | 2022 |
[Diagnosis of primary hyperaldosteronism].
Topics: Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 2022 |
Prognosis of adrenalectomy guided by computed tomography versus adrenal vein sampling in patients with primary aldosteronism: A systematic review and meta-analysis.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Prognosis; Ret | 2022 |
Primary Aldosteronism: Where Are We Now? Where to From Here?
Topics: Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Sodium, Dietary | 2022 |
The Role of Aldosterone in OSA and OSA-Related Hypertension.
Topics: Aldosterone; Continuous Positive Airway Pressure; Humans; Hyperaldosteronism; Hypertension; Sleep Ap | 2021 |
High Prevalence of Autonomous Aldosterone Production in Hypertension: How to Identify and Treat It.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Prevalence; Renin | 2022 |
Chronic hypertension and superimposed preeclampsia: screening and diagnosis.
Topics: Aldosterone; Angiogenic Proteins; Biomarkers; Chronic Disease; Cytokines; Female; Humans; Hypertensi | 2022 |
Mosaic theory revised: inflammation and salt play central roles in arterial hypertension.
Topics: Aldosterone; Humans; Hypertension; Inflammation; Sodium Chloride, Dietary | 2022 |
Hyperaldosteronism: How Current Concepts Are Transforming the Diagnostic and Therapeutic Paradigm.
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 2020 |
Aldosterone and cardiovascular diseases.
Topics: Aldosterone; Atherosclerosis; Atrial Fibrillation; Cardiovascular Diseases; Heart Failure; Humans; H | 2023 |
Aldosterone breakthrough from a pharmacological perspective.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypertension | 2022 |
11-Deoxycorticosterone Producing Adrenal Hyperplasia as a Very Unusual Cause of Endocrine Hypertension: Case Report and Systematic Review of the Literature.
Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Carcinoma; Desoxycorti | 2022 |
Diagnostic value of aldosterone to renin ratio calculated by plasma renin activity or plasma renin concentration in primary aldosteronism: a meta-analysis.
Topics: Aldosterone; Area Under Curve; Humans; Hyperaldosteronism; Hypertension; Renin | 2022 |
Primary Aldosteronism and Resistant Hypertension: A Pathophysiological Insight.
Topics: Aldosterone; Fibrosis; Humans; Hyperaldosteronism; Hypertension; Kidney | 2022 |
Performance of the aldosterone-to-renin ratio as a screening test for primary aldosteronism in primary care.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Primary Health Care; Renin | 2022 |
Renin-Angiotensin Aldosterone System Inhibitors and COVID-19: A Systematic Review and Meta-Analysis Revealing Critical Bias Across a Body of Observational Research.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonis | 2022 |
Management and Outcomes of Primary Aldosteronism in Pregnancy: A Systematic Review.
Topics: Adrenalectomy; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Pregnancy; Retrospecti | 2022 |
Renin-Angiotensin-Aldosterone Inhibitors and COVID-19 Infection.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angi | 2022 |
Pathogenesis of Primary Aldosteronism: Impact on Clinical Outcome.
Topics: Adrenocortical Adenoma; Aldosterone; Cytochrome P-450 CYP11B2; G Protein-Coupled Inwardly-Rectifying | 2022 |
Update on the Genetics of Primary Aldosteronism and Aldosterone-Producing Adenomas.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Aldosterone; G P | 2022 |
Focus on adrenal and related causes of hypertension in childhood and adolescence: Rare or rarely recognized?
Topics: Adolescent; Adult; Aldosterone; Child; Humans; Hydrocortisone; Hypertension | 2022 |
Salt Sensitivity of Blood Pressure in Women.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Receptors, Mineralo | 2023 |
Primary aldosteronism - a multidimensional syndrome.
Topics: Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Risk Factors; Syndrome | 2022 |
Influence and implications of the renin-angiotensin-aldosterone system in obstructive sleep apnea: An updated systematic review and meta-analysis.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Hormones; Humans; Hypertension; Renin; Renin-Angiotensi | 2023 |
Salt, Not Always a Cardiovascular Enemy? A Mini-Review and Modern Perspective.
Topics: Aldosterone; Blood Pressure; Endothelin-1; Humans; Hypertension; Nitric Oxide; Receptors, Mineraloco | 2022 |
Promise of Physiological Profiling to Prevent Stroke in People of African Ancestry: Prototyping Ghana.
Topics: Aldosterone; Antihypertensive Agents; Ghana; Humans; Hypertension; Multicenter Studies as Topic; Ren | 2022 |
Role of α1-blockers in the current management of hypertension.
Topics: Adrenergic alpha-Antagonists; Aged; Aldosterone; Antihypertensive Agents; Diuretics; Doxazosin; Huma | 2022 |
Who should be screened for primary aldosteronism? A comprehensive review of current evidence.
Topics: Adrenal Gland Neoplasms; Aldosterone; Diuretics; Humans; Hyperaldosteronism; Hypertension; Renin | 2022 |
Blood pressure effects of sodium transport along the distal nephron.
Topics: Aldosterone; Animals; Blood Pressure; Humans; Hypertension; Mammals; Nephrons; Sodium | 2022 |
Primary aldosteronism and obstructive sleep apnea: What do we know thus far?
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Sleep Apnea, Obstructive | 2022 |
Personalized Treatment of Patients With Primary Aldosteronism.
Topics: Aldosterone; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Patient-Cente | 2023 |
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors | 2022 |
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors | 2022 |
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors | 2022 |
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors | 2022 |
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors | 2022 |
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors | 2022 |
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors | 2022 |
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors | 2022 |
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors | 2022 |
Vascular and hormonal interactions in the adrenal gland.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldoster | 2022 |
Vascular and hormonal interactions in the adrenal gland.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldoster | 2022 |
Vascular and hormonal interactions in the adrenal gland.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldoster | 2022 |
Vascular and hormonal interactions in the adrenal gland.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldoster | 2022 |
CASZ1: a promising factor modulating aldosterone biosynthesis and mineralocorticoid receptor activity.
Topics: Aldosterone; Chromatography, Liquid; DNA-Binding Proteins; Genome-Wide Association Study; Humans; Hy | 2023 |
CASZ1: a promising factor modulating aldosterone biosynthesis and mineralocorticoid receptor activity.
Topics: Aldosterone; Chromatography, Liquid; DNA-Binding Proteins; Genome-Wide Association Study; Humans; Hy | 2023 |
CASZ1: a promising factor modulating aldosterone biosynthesis and mineralocorticoid receptor activity.
Topics: Aldosterone; Chromatography, Liquid; DNA-Binding Proteins; Genome-Wide Association Study; Humans; Hy | 2023 |
CASZ1: a promising factor modulating aldosterone biosynthesis and mineralocorticoid receptor activity.
Topics: Aldosterone; Chromatography, Liquid; DNA-Binding Proteins; Genome-Wide Association Study; Humans; Hy | 2023 |
[The genetic background of primary aldosteronism].
Topics: Adrenocortical Adenoma; Aldosterone; Genetic Background; Humans; Hyperaldosteronism; Hypertension | 2023 |
Cardiovascular and metabolic characters of
Topics: Adenoma; Adrenocortical Adenoma; Aldosterone; Female; G Protein-Coupled Inwardly-Rectifying Potassiu | 2023 |
Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American
Topics: Aldosterone; American Heart Association; Cardiovascular Diseases; Female; Humans; Hypertension; Moth | 2023 |
Underdiagnosis of Primary Aldosteronism: A Review of Screening and Detection.
Topics: Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Renin | 2023 |
The Effect of Aldosterone on Cardiorenal and Metabolic Systems.
Topics: Aldosterone; Cardiovascular Diseases; Essential Hypertension; Humans; Hyperaldosteronism; Hypertensi | 2023 |
Primary Aldosteronism Prevalence - An Unfolding Story.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Prevalence; Renin | 2023 |
Prognostic models to predict complete resolution of hypertension after adrenalectomy in primary aldosteronism: A systematic review and meta-analysis.
Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Progno | 2023 |
Improving Detection Rates for Primary Aldosteronism.
Topics: Aldosterone; Blood Pressure; Heart Disease Risk Factors; Humans; Hyperaldosteronism; Hypertension; P | 2023 |
Recent progress in the diagnosis and treatment of primary aldosteronism.
Topics: Aldosterone; Glucose; Humans; Hyperaldosteronism; Hyperkalemia; Hypertension; Mineralocorticoid Rece | 2023 |
Ca
Topics: Aldosterone; Calcium Channels, T-Type; Calcium Signaling; Humans; Hyperaldosteronism; Hypertension; | 2023 |
Advances in the molecular imaging of primary aldosteronism.
Topics: Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Molecular Imaging; Tomography | 2023 |
Mineralocorticoid receptor signalling in primary aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Quali | 2023 |
Role of NCC in the pathophysiology of hypertension in primary aldosteronism.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Kidney Tubules, Distal; Phosp | 2023 |
G protein-coupled estrogen receptor: a promising therapeutic target for aldosterone-induced hypertension.
Topics: Aldosterone; Estrogens; Female; GTP-Binding Proteins; Humans; Hypertension; Receptors, Estrogen; Rec | 2023 |
Key to the Treatment of Primary Aldosteronism in Secondary Hypertension: Subtype Diagnosis.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertensi | 2023 |
Primary aldosteronism 2.0: an update for clinicians on diagnosis and treatment.
Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2023 |
Therapeutic management of congenital forms of endocrine hypertension.
Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocort | 2023 |
A low dietary sodium dose is associated with a more pronounced aldosterone response in normotensive than in hypertensive individuals.
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Randomized Controlled Trials as Topic; Sodium; So | 2023 |
Antifibrotic Roles of RAAS Blockers: Update.
Topics: Aldosterone; Angiotensin I; Blood Pressure; Humans; Hypertension; Mineralocorticoid Receptor Antagon | 2019 |
Steroid Profiling and Immunohistochemistry for Subtyping and Outcome Prediction in Primary Aldosteronism-a Review.
Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Chromatography, Liquid; Cytochrome P- | 2019 |
Mineralocorticoid Receptor and Endothelial Dysfunction in Hypertension.
Topics: Aldosterone; Animals; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Epithelial S | 2019 |
Monogenic hypertension.
Topics: Aldosterone; Genetic Testing; High-Throughput Nucleotide Sequencing; Humans; Hydrocortisone; Hyperte | 2019 |
Low-Renin Hypertension.
Topics: Aldosterone; Citrus paradisi; Cushing Syndrome; Glycyrrhiza; Humans; Hyperaldosteronism; Hypertensio | 2019 |
Resistant Hypertension: A Clinical Perspective.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Liddle Syndrome; Renin | 2019 |
[Secondary hypertension in women].
Topics: Adult; Age Factors; Aldosterone; Computed Tomography Angiography; Female; Fibromuscular Dysplasia; H | 2019 |
Arterial Hypertension, Aldosterone, and Atrial Fibrillation.
Topics: Aldosterone; Atrial Fibrillation; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Randomize | 2019 |
[Hormonal Assessment of Secondary Hypertension - How to do it and what to expect?]
Topics: Aldosterone; Antihypertensive Agents; Blood Chemical Analysis; Diagnosis, Differential; Diagnostic T | 2019 |
Primary Aldosteronism: JACC State-of-the-Art Review.
Topics: Adrenal Glands; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension | 2019 |
Primary aldosteronism: Treatment of the disease, and new therapeutic approaches.
Topics: Adrenalectomy; Aldosterone; Antihypertensive Agents; Endocrinology; Humans; Hyperaldosteronism; Hype | 2020 |
Associations between primary aldosteronism and diabetes, poor bone health, and sleep apnea-what do we know so far?
Topics: Aldosterone; Bone Density; Diabetes Mellitus; Disease Management; Humans; Hyperaldosteronism; Hypert | 2020 |
Prevalence, diagnosis and outcomes of treatment for primary aldosteronism.
Topics: Adrenal Gland Neoplasms; Adrenocortical Adenoma; Aldosterone; Diagnostic Techniques, Endocrine; Huma | 2020 |
The importance of the epithelial sodium channel in determining salt sensitivity in people of African origin.
Topics: Aldosterone; Amiloride; Blood Pressure; Epithelial Sodium Channels; Humans; Hypertension; Sodium; So | 2021 |
Sodium pumps, ouabain and aldosterone in the brain: A neuromodulatory pathway underlying salt-sensitive hypertension and heart failure.
Topics: Aldosterone; Animals; Brain; Heart Failure; Humans; Hypertension; Ouabain; Sodium Chloride, Dietary; | 2020 |
Old and new genes in primary aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Genetic Association Studies; Genetic | 2020 |
Recent insights into sodium and potassium handling by the aldosterone-sensitive distal nephron: implications on pathophysiology and drug discovery.
Topics: Aldosterone; Drug Discovery; Humans; Hypertension; Nephrons; Potassium; Sodium | 2020 |
The spectrum of low-renin hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Molecular Diagnostic Techniques; Renin | 2020 |
MicroRNAs and Adrenocortical Tumors: Where do we Stand on Primary Aldosteronism?
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertens | 2020 |
Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II Type 1 Receptor Blocke | 2020 |
The cardiovascular consequences of hyperaldosteronism.
Topics: Aldosterone; Blood Pressure; Cardiovascular Diseases; Humans; Hyperaldosteronism; Hypertension | 2021 |
The Potential Role of Aldosterone-Producing Cell Clusters in Adrenal Disease.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Cytoc | 2020 |
Salt Appetite and its Effects on Cardiovascular Risk in Primary Aldosteronism.
Topics: Aldosterone; Appetite; Cardiovascular Diseases; Feeding Behavior; Heart Disease Risk Factors; Humans | 2020 |
Hypokalemia and the Prevalence of Primary Aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Disease Progression; Humans; Hyperald | 2020 |
Primary aldosteronism is a public health issue: challenges and opportunities.
Topics: Aldosterone; Blood Pressure; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension; Publi | 2020 |
Renin-angiotensin-aldosterone system and COVID-19 infection.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-C | 2020 |
Oxidative Stress: A Unifying Paradigm in Hypertension.
Topics: Aldosterone; Angiotensin II; Endothelin-1; Endothelium, Vascular; Humans; Hypertension; Inflammation | 2020 |
Aldosterone receptor antagonists.
Topics: Aldosterone; Blood Pressure; Heart Failure; Humans; Hypertension; Mineralocorticoid Receptor Antagon | 2021 |
[Update and Research Progress in the Diagnosis of Primary Aldosteronism].
Topics: Aldosterone; Captopril; Humans; Hyperaldosteronism; Hypertension; Renin | 2020 |
Genetic and Genomic Mechanisms of Primary Aldosteronism.
Topics: Adrenocortical Adenoma; Aldosterone; Animals; Calcium Signaling; Genetics; Genomics; Humans; Hyperal | 2020 |
Treatment of primary hyperaldosteronism.
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Ant | 2020 |
Pathogenesis and treatment of primary aldosteronism.
Topics: Adrenal Glands; Aldosterone; Animals; Humans; Hyperaldosteronism; Hypertension; Mutation | 2020 |
Aldosterone, Inflammation, Immune System, and Hypertension.
Topics: Aldosterone; Blood Pressure; Cardiometabolic Risk Factors; Humans; Hypertension; Immunity; Water-Ele | 2021 |
Evolution of the Primary Aldosteronism Syndrome: Updating the Approach.
Topics: Aldosterone; Blood Pressure; Diagnostic Techniques, Endocrine; Humans; Hyperaldosteronism; Hypertens | 2020 |
Five Reasons for the Failure to Diagnose Aldosterone Excess in Hypertension.
Topics: Aldosterone; Diagnosis, Differential; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension | 2020 |
Left ventricular remodeling and dysfunction in primary aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypertrophy, Left Ventricular; Ventricular Dy | 2021 |
Female Sex, a Major Risk Factor for Salt-Sensitive Hypertension.
Topics: Aldosterone; Female; Humans; Hypertension; Male; Receptors, Mineralocorticoid; Risk Factors; Sodium | 2020 |
Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride.
Topics: Aldosterone; Asian People; Bias; Black People; Blood Pressure; Catecholamines; Cholesterol; Confiden | 2020 |
Confounders of the aldosterone-to-renin ratio when used as a screening test in hypertensive patients: A critical analysis of the literature.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Renin-Angiotensin System | 2021 |
The Mineralocorticoid Receptor in Salt-Sensitive Hypertension and Renal Injury.
Topics: Acute Kidney Injury; Aldosterone; Humans; Hypertension; Metabolic Syndrome; Receptors, Mineralocorti | 2021 |
The effect of medication on the aldosterone-to-renin ratio. A critical review of the literature.
Topics: Aldosterone; Antihypertensive Agents; Humans; Hyperaldosteronism; Hypertension; Renin | 2021 |
China nationwide screening and registry of primary aldosteronism in hypertensive patients.
Topics: Aldosterone; China; Humans; Hyperaldosteronism; Hypertension; Multicenter Studies as Topic; Prospect | 2021 |
Aldosterone sensitivity: an opportunity to explore the pathogenesis of hypertension.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Drug Resistance; Humans; Hypertension | 2021 |
The mineralocorticoid receptor-an emerging player in metabolic syndrome?
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Metabolic Syndrome; Mineralocorticoid Recepto | 2021 |
New Genetic Polymorphisms as an Epidemiological Factor of Arterial Hypertension in Patients with Hyposodical Diet.
Topics: Aldosterone; Diet; Humans; Hypertension; Polymorphism, Genetic; Renin; Renin-Angiotensin System; Sod | 2022 |
[Hyperaldosteronism].
Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Minera | 2021 |
Kidney and epigenetic mechanisms of salt-sensitive hypertension.
Topics: Aging; Aldosterone; Angiotensin II; Animals; DNA Methylation; Fetal Nutrition Disorders; Glucuronida | 2021 |
How common is primary aldosteronism?
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 2021 |
Functional Characteristic and Significance of Aldosterone-Producing Cell Clusters in Primary Aldosteronism and Age-Related Hypertension.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Age Factors; Aging; Aldosterone; H | 2021 |
Primary aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Prevalence; Renin | 2022 |
Pathophysiology of Hypertension: The Mosaic Theory and Beyond.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Blood Vessels; Body Fluids; Central Nervous System; Hum | 2021 |
Unravelling the Genetic Basis of Primary Aldosteronism.
Topics: Aldosterone; Germ-Line Mutation; High-Throughput Nucleotide Sequencing; Humans; Hyperaldosteronism; | 2021 |
DNA Methylation of the Angiotensinogen Gene,
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Cardiovascular Diseases; CCAAT-Enhancer-Binding Protei | 2021 |
A systematic review of nonsynonymous single nucleotide polymorphisms in the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Humans; Hypertension; Polymorphism, Single Nucleotide; Renin; Renin-Angiotensin System | 2022 |
Sexual Dimorphism of Corticosteroid Signaling during Kidney Development.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Blood Pressure; Gene Expression Regulation, Developme | 2021 |
Therapeutic Outcomes with Surgical and Medical Management of Primary Aldosteronism.
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Ant | 2021 |
Chronic use of renin-angiotensin-aldosterone inhibitors in hypertensive COVID-19 patients: Results from a Spanish registry and meta-analysis.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensins; Antihypertensive Agents; COVID-19; Huma | 2022 |
Primary Aldosteronism: a Continuum from Normotension to Hypertension.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Kidney; Renin | 2021 |
Sex steroids receptors, hypertension, and vascular ageing.
Topics: Adolescent; Aging; Aldosterone; Female; Humans; Hypertension; Male; Receptors, Steroid; Renin-Angiot | 2022 |
Primary Aldosteronism Presenting with Hypertension Five Days after Delivery: A Case Report and Literature Review.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Female; Humans; | 2022 |
Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride.
Topics: Aldosterone; Asian People; Black People; Blood Pressure; Catecholamines; Cholesterol; Diet, Sodium-R | 2017 |
Mineralocorticoid Receptor Blockade in End-Stage Renal Disease.
Topics: Aldosterone; Humans; Hypertension; Kidney Failure, Chronic; Mineralocorticoid Receptor Antagonists; | 2017 |
Primary aldosteronism: a common cause of resistant hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 2017 |
The association between consistent licorice ingestion, hypertension and hypokalaemia: a systematic review and meta-analysis.
Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Female; Glycyrrhiza; Glycyrrhizic Acid; Humans; Hype | 2017 |
Adrenal venous sampling for primary aldosteronism: laboratory medicine best practice.
Topics: Adrenal Cortex Function Tests; Adrenal Glands; Aldosterone; Biomarkers; Blood Specimen Collection; H | 2017 |
Endothelial factors in the pathogenesis and treatment of chronic kidney disease Part I: General mechanisms: a joint consensus statement from the European Society of Hypertension Working Group on Endothelin and Endothelial Factors and The Japanese Society
Topics: Aldosterone; Animals; Arterial Pressure; Consensus; Endothelin-1; Endothelium, Vascular; Fibrosis; G | 2018 |
Primary Aldosteronism and Obstructive Sleep Apnea: Is This A Bidirectional Relationship?
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Prevalence; Risk Factors; Sle | 2017 |
Aging and Adrenal Aldosterone Production.
Topics: Adrenal Cortex; Aging; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mutation | 2018 |
Overview of aldosterone-related genetic syndromes and recent advances.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Age Factors; Aging; Aldosterone; C | 2018 |
Primary aldosteronism in the primary care setting.
Topics: Adrenalectomy; Aldosterone; Blood Pressure; Cardiovascular Diseases; Cerebrovascular Disorders; Huma | 2018 |
Hypertension in Blacks: Individualized Therapy Based on Renin/Aldosterone Phenotyping.
Topics: Aldosterone; Antihypertensive Agents; Black People; Blood Pressure; Global Health; Humans; Hypertens | 2018 |
Role of Renin-Angiotensin-Aldosterone System Activation in Promoting Cardiovascular Fibrosis and Stiffness.
Topics: Aldosterone; Cardiovascular Diseases; Cardiovascular System; Fibrosis; Humans; Hypertension; Models, | 2018 |
Primary Aldosteronism: Practical Approach to Diagnosis and Management.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hyperal | 2018 |
Leptin and Aldosterone.
Topics: Aldosterone; Animals; Female; Gene Expression Regulation; Humans; Hypertension; Leptin; Male; Obesit | 2019 |
The renin-angiotensin-aldosterone system and its suppression.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit | 2019 |
Eplerenone Versus Spironolactone in Resistant Hypertension: an Efficacy and/or Cost or Just a Men's Issue?
Topics: Aldosterone; Antihypertensive Agents; Eplerenone; Humans; Hypertension; Mineralocorticoid Receptor A | 2019 |
Treatment of Resistant and Refractory Hypertension.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Drug Resistance; Drug Therapy, Combin | 2019 |
Role of Pendrin in the Pathophysiology of Aldosterone-Induced Hypertension.
Topics: Acid-Base Equilibrium; Aldosterone; Animals; Blood Pressure; Humans; Hyperaldosteronism; Hypertensio | 2019 |
The aldosterone to renin ratio in the diagnosis of primary aldosteronism: Promises and challenges.
Topics: Aldosterone; Biomarkers; Humans; Hyperaldosteronism; Hypertension; Practice Guidelines as Topic; Ren | 2019 |
Obesity, kidney dysfunction and hypertension: mechanistic links.
Topics: Adipokines; Aldosterone; Angiotensin II; Humans; Hypertension; Kidney; Kidney Tubules; Leptin; Obesi | 2019 |
K
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Potassium; Reni | 2019 |
[Update in the clinical management of low renin hypertension].
Topics: Aldosterone; Disease Management; Humans; Hypertension; Receptors, Mineralocorticoid; Renin; Renin-An | 2019 |
Effectiveness of Thermal Ablation for Aldosterone-Producing Adrenal Adenoma: A Systematic Review and Meta-Analysis of Clinical and Biochemical Parameters.
Topics: Ablation Techniques; Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Antihypertensive Agents; | 2019 |
ENaC modulators and renal disease.
Topics: Aldosterone; Diuretics; Epithelial Sodium Channel Agonists; Epithelial Sodium Channel Blockers; Epit | 2013 |
Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials.
Topics: Aldosterone; Biomarkers; Blood Pressure; Cardiovascular Diseases; Diet, Sodium-Restricted; Female; H | 2013 |
Pathophysiology of genetic deficiency in tissue kallikrein activity in mouse and man.
Topics: Aldosterone; Animals; Blood Pressure; Diabetes Mellitus; Humans; Hypertension; Ischemia; Kidney; Kin | 2013 |
Immune system alterations by aldosterone during hypertension: from clinical observations to genomic and non-genomic mechanisms leading to vascular damage.
Topics: Aldosterone; Blood Vessels; Genome, Human; Humans; Hypertension; Immune System; Oxidative Stress | 2013 |
Genetics of mineralocorticoid excess: an update for clinicians.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Animals; Disease Models, Animal; G Pr | 2013 |
Effect of longer-term modest salt reduction on blood pressure.
Topics: Age Factors; Aldosterone; Blood Pressure; Humans; Hypertension; Lipids; Norepinephrine; Randomized C | 2013 |
Smooth muscle cell mineralocorticoid receptors: role in vascular function and contribution to cardiovascular disease.
Topics: Aging; Aldosterone; Angiotensin II; Animals; Atherosclerosis; Blood Pressure; Cardiovascular Disease | 2013 |
Inhibition of the renin-angiotensin-aldosterone system for cerebrorenal protection.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyperte | 2013 |
Aldosterone mediates cardiac fibrosis in the setting of hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Cytochrome P-450 CYP11B2; Fibrosis; Heart Diseases; Humans; Hy | 2013 |
A critical review of the evidence supporting aldosterone in the etiology and its blockade in the treatment of obesity-associated hypertension.
Topics: Aldosterone; Evidence-Based Medicine; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; | 2014 |
Diagnosis and management of primary aldosteronism: an updated review.
Topics: Adenoma; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenalectomy; Aldosterone; Humans; Hypera | 2013 |
Mineralocorticoid receptors in vascular disease: connecting molecular pathways to clinical implications.
Topics: Aldosterone; Animals; Atherosclerosis; Blood Pressure; Cardiovascular Diseases; Disease Progression; | 2013 |
Regulation of aldosterone biosynthesis by the Kir3.4 (KCNJ5) potassium channel.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II; Cell Membrane; G Prot | 2013 |
Aldosterone receptor antagonists: current perspectives and therapies.
Topics: Aldosterone; Animals; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Rec | 2013 |
Sex differences in angiotensin II- and aldosterone-induced hypertension: the central protective effects of estrogen.
Topics: Aldosterone; Angiotensin II; Animals; Brain; Estrogens; Humans; Hypertension; Models, Biological; Re | 2013 |
Aldosterone synthase inhibition in hypertension.
Topics: Aldosterone; Animals; Antihypertensive Agents; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Humans; | 2013 |
Endocrine and hypertensive disorders of potassium regulation: primary aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Eplerenone; Humans; Hy | 2013 |
Diagnosis and treatment of unilateral forms of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hyper | 2013 |
Primary aldosteronism: a new insight into pathogenesis, diagnosis, and treatment in hypertensive patients.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Mineralocorticoid Receptor Antag | 2013 |
Aberrant Rac1-mineralocorticoid receptor pathways in salt-sensitive hypertension.
Topics: Aldosterone; Animals; Humans; Hypertension; Kidney; Metabolic Syndrome; rac1 GTP-Binding Protein; Ra | 2013 |
Aldosterone and blood pressure regulation: recent milestones on the long and winding road from electrocortin to KCNJ5, GPER, and beyond.
Topics: Aldosterone; Blood Pressure; Cardiovascular System; G Protein-Coupled Inwardly-Rectifying Potassium | 2014 |
[Presentations and management of adrenal hypertension].
Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; | 2014 |
Regulation of Potassium Homeostasis.
Topics: Aldosterone; Animals; Circadian Rhythm; Homeostasis; Humans; Hypertension; Kidney; Potassium; Renal | 2015 |
Actions of circulating angiotensin II and aldosterone in the brain contributing to hypertension.
Topics: Aldosterone; Angiotensin II; Brain Chemistry; Humans; Hypertension; Neurotransmitter Agents; Renin-A | 2014 |
Aldosterone excess and resistant hypertension: investigation and treatment.
Topics: Aldosterone; Animals; Drug Resistance; Humans; Hypertension; Quality of Life; Renin; Reproducibility | 2014 |
[Renin-aldosterone and bone metabolism].
Topics: Acute Kidney Injury; Aldosterone; Angiotensin II; Animals; Bone and Bones; Calcium; Cardiovascular D | 2014 |
The inextricable role of the kidney in hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Homeostasis; Humans; Hypertension; Kidney; Models, Biological; | 2014 |
[Organ damage and cardiorenal syndrome in acute heart failure].
Topics: Aldosterone; Cardiac Output; Cardio-Renal Syndrome; Comorbidity; Endothelium, Vascular; Heart Failur | 2014 |
Expression and gene variation studies deny association of human HSD3B1 gene with aldosterone production or blood pressure.
Topics: Adrenal Cortex; Aged; Aldosterone; Blood Pressure; Cells, Cultured; Female; Gene Expression Regulati | 2015 |
Resistant hypertension in diabetes mellitus.
Topics: Aldosterone; Diabetes Mellitus; Humans; Hypertension; Leptin; Obesity; Sympathetic Nervous System | 2014 |
Comparison of agents that affect aldosterone action.
Topics: Aldosterone; Animals; Epithelial Sodium Channel Blockers; Humans; Hydrocortisone; Hyperaldosteronism | 2014 |
Aldosterone and volume management in hypertensive heart disease.
Topics: Aldosterone; Area Under Curve; Diuretics; Eplerenone; Heart Failure; Humans; Hypertension; Mineraloc | 2014 |
Increased aldosterone: mechanism of hypertension in obesity.
Topics: Aldosterone; Antihypertensive Agents; Humans; Hypertension; Obesity | 2014 |
Clock genes in hypertension: novel insights from rodent models.
Topics: Aldosterone; Animals; ARNTL Transcription Factors; Blood Vessels; Circadian Rhythm; CLOCK Proteins; | 2014 |
Bidirectional relationship of hypertension with obstructive sleep apnea.
Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Continuous Positive Airway Pressure; Die | 2014 |
[Primary hyperaldosteronism: boundaries of diagnostics and therapy].
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adrenocortical Hyperfunction; Aldos | 2014 |
Effects of T-type calcium channel blockers on renal function and aldosterone in patients with hypertension: a systematic review and meta-analysis.
Topics: Adult; Aged; Aldosterone; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Ty | 2014 |
Update in primary aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Quality of Life | 2015 |
Mineralocorticoid receptor activation and mineralocorticoid receptor antagonist treatment in cardiac and renal diseases.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Blood Pressure; Clinical Trials as Topi | 2015 |
Mineralocorticoid-induced sodium appetite and renal salt retention: evidence for common signaling and effector mechanisms.
Topics: Aldosterone; Angiotensin II; Animals; Appetite; Blood Pressure; Epithelial Sodium Channels; Humans; | 2014 |
Pathogenesis of drug-resistant hypertension.
Topics: Age Factors; Aldosterone; Blood Pressure; Coronary Vasospasm; Drug Resistance; Humans; Hypertension; | 2014 |
Pathophysiology and treatment of resistant hypertension: the role of aldosterone and amiloride-sensitive sodium channels.
Topics: Aldosterone; Amiloride; Antihypertensive Agents; Blood Pressure; Coronary Vasospasm; Diuretics; Drug | 2014 |
The mineralocorticoid receptor: a new player controlling energy homeostasis.
Topics: Adipose Tissue; Aldosterone; Animals; Energy Metabolism; Homeostasis; Humans; Hypertension; Metaboli | 2013 |
Apparent treatment-resistant hypertension and chronic kidney disease: another cardiovascular-renal syndrome?
Topics: Aldosterone; Antihypertensive Agents; Blood Volume; Cardio-Renal Syndrome; Coronary Vasospasm; Diure | 2014 |
Dual renin-angiotensin-aldosterone blockade: promises and pitfalls.
Topics: Aldosterone; Angiotensins; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Mineraloco | 2015 |
Comparison of aldosterone synthesis in adrenal cells, effect of various AT1 receptor blockers with or without atrial natriuretic peptide.
Topics: Adrenal Glands; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Atrial Natriuretic Factor; Cel | 2015 |
Recent topics on podocytes and aldosterone.
Topics: Aldosterone; Animals; Disease Models, Animal; Humans; Hypertension; Metabolic Syndrome; Mice; Podocy | 2015 |
Renal mechanisms of salt-sensitive hypertension: contribution of two steroid receptor-associated pathways.
Topics: Aldosterone; Animals; Circadian Rhythm; Disease Models, Animal; Epithelial Sodium Channels; Humans; | 2015 |
Transforming growth factor beta1 and aldosterone.
Topics: Aldosterone; Animals; Humans; Hypertension; Kidney; Renin-Angiotensin System; Sodium; Transforming G | 2015 |
Laboratory challenges in primary aldosteronism screening and diagnosis.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Practice Guidelines as Topic; | 2015 |
[Hypertension in the course of primary aldosteronism during pregnancy].
Topics: Acid Sensing Ion Channel Blockers; Aldosterone; Amiloride; Antihypertensive Agents; Eplerenone; Fema | 2015 |
Hypertension: renin-angiotensin-aldosterone system alterations.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim | 2015 |
Obesity-induced hypertension: interaction of neurohumoral and renal mechanisms.
Topics: Aldosterone; Animals; Antihypertensive Agents; Dyslipidemias; Heart Conduction System; Hemodynamics; | 2015 |
Relative roles of principal and intercalated cells in the regulation of sodium balance and blood pressure.
Topics: Aldosterone; Animals; Biological Transport; Blood Pressure; Humans; Hypertension; Kidney; Sodium; So | 2015 |
Issues in the Diagnosis and Treatment of Primary Aldosteronism.
Topics: Aldosterone; Biomarkers; Critical Pathways; Humans; Hyperaldosteronism; Hypertension; Practice Guide | 2016 |
Mineralocorticoid and apparent mineralocorticoid syndromes of secondary hypertension.
Topics: Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocortical Adenoma; Aldosterone; Drug | 2015 |
[Genetic alterations in primary aldosteronism].
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Animals; Calcium Channels, L-Type; G | 2015 |
Atlas of tissue renin-angiotensin-aldosterone system in human: A transcriptomic meta-analysis.
Topics: Aldosterone; Cluster Analysis; Databases, Factual; Gene Expression; Humans; Hypertension; Multigene | 2015 |
Renin and aldosterone measurements in the management of arterial hypertension.
Topics: Aldosterone; Humans; Hypertension; Renin | 2015 |
Aldosterone biosynthesis in the human adrenal cortex and associated disorders.
Topics: Adrenal Cortex; Aldosterone; Biosynthetic Pathways; Gene Expression Regulation; Humans; Hyperaldoste | 2015 |
Aldosterone and the Mineralocorticoid Receptor: Risk Factors for Cardiometabolic Disorders.
Topics: Aldosterone; Cardiovascular Diseases; Humans; Hypertension; Metabolic Syndrome; Obesity; Receptors, | 2015 |
Reviving the use of aldosterone inhibitors in treating hypertension in obesity.
Topics: Aldosterone; Animals; Evidence-Based Medicine; Humans; Hypertension; Mineralocorticoid Receptor Anta | 2015 |
Pharmacological treatment of aldosterone excess.
Topics: Aldosterone; Cytochrome P-450 CYP11B2; Dihydropyridines; Drug Interactions; Epithelial Sodium Channe | 2015 |
The roles of sensitization and neuroplasticity in the long-term regulation of blood pressure and hypertension.
Topics: Adaptation, Physiological; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiovascular Syst | 2015 |
[Primary aldosteronism: new insights into familial forms].
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; DNA Mutational Analysis; G Protein-Co | 2015 |
Aldosterone and Left Ventricular Remodeling.
Topics: Aldosterone; Essential Hypertension; Heart Ventricles; Humans; Hyperaldosteronism; Hypertension; Ven | 2015 |
Urinary extracellular vesicles as markers to assess kidney sodium transport.
Topics: Aldosterone; Animals; Biomarkers; Epithelial Sodium Channels; Extracellular Vesicles; Humans; Hypert | 2016 |
The potential of targeting CYP11B.
Topics: Aldosterone; Animals; Cardiomegaly; Cytochrome P-450 CYP11B2; Drug Design; Humans; Hypertension; Imi | 2016 |
Resistant Hypertension and the Pivotal Role for Mineralocorticoid Receptor Antagonists: A Clinical Update 2016.
Topics: Age Factors; Aldosterone; Blood Pressure Monitoring, Ambulatory; Comorbidity; Diabetes Mellitus; Hum | 2016 |
The Role of Aldosterone in Obesity-Related Hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Caloric Restriction; Diet, Sodium-Restricted; Humans; Hyperald | 2016 |
The Different Therapeutic Choices with ARBs. Which One to Give? When? Why?
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressu | 2016 |
Apparent mineralocorticoid excess.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Antihypertensive Agents; Cortisone; Diagno | 2017 |
Hyperaldosteronism: Screening and Diagnostic Tests.
Topics: Aldosterone; Biomarkers; Critical Pathways; Humans; Hyperaldosteronism; Hypertension; Mass Screening | 2016 |
Hyperaldosteronism: How to Discriminate Among Different Disease Forms?
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Aldosterone; Biomarkers; Diagnos | 2016 |
Potassium: friend or foe?
Topics: Aldosterone; Cation Exchange Resins; Cell Membrane; Child; Heart Failure; Homeostasis; Humans; Hyper | 2017 |
Vascular Mineralocorticoid Receptors: Linking Risk Factors, Hypertension, and Heart Disease.
Topics: Aldosterone; Blood Vessels; Heart Diseases; Humans; Hypertension; Receptors, Mineralocorticoid; Risk | 2016 |
Syndromes that Mimic an Excess of Mineralocorticoids.
Topics: Aldosterone; Biomarkers; Cushing Syndrome; Dexamethasone; Diet; Genetic Predisposition to Disease; G | 2016 |
Obesity, hypertension and aldosterone: is leptin the link?
Topics: Adipose Tissue; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Leptin; Male; Obesity | 2016 |
Adipocytes, aldosterone and obesity-related hypertension.
Topics: Adipocytes; Adrenal Glands; Aldosterone; Animals; Biomarkers; Energy Metabolism; Gene Expression Reg | 2016 |
Clock genes and salt-sensitive hypertension: a new type of aldosterone-synthesizing enzyme controlled by the circadian clock and angiotensin II.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldosterone; Angiotensin II; Animals; Circadian Clocks; Circadian R | 2016 |
Sodium and potassium in the pathogenesis of hypertension: focus on the brain.
Topics: Aldosterone; Angiotensin II; Animals; Brain; Humans; Hypertension; Ouabain; Oxidative Stress; Potass | 2017 |
Vascular Consequences of Aldosterone Excess and Mineralocorticoid Receptor Antagonism.
Topics: Aldosterone; Animals; Cardiovascular Diseases; Endothelium, Vascular; Epithelial Cells; Humans; Hype | 2017 |
Radiofrequency ablation treatment for aldosterone-producing adenomas.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Catheter Ablation; Hum | 2017 |
ACTH and Polymorphisms at Steroidogenic Loci as Determinants of Aldosterone Secretion and Blood Pressure.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure; Cytochrome P-450 CYP11B2; Genetic | 2017 |
Role of the renin-angiotensin system in vascular inflammation.
Topics: Aldosterone; Angiotensin II; Animals; Capillary Permeability; Chemokine CCL2; Humans; Hypertension; | 2008 |
The role of aldosterone in cardiovascular disease in people with diabetes and hypertension: an update.
Topics: Aldosterone; Cardiovascular Diseases; Diabetes Complications; Humans; Hypertension; Insulin Resistan | 2008 |
[System renin-aldosterone in fat tissue and other organ and tissues].
Topics: Adipose Tissue; Aldosterone; Humans; Hypertension; Metabolic Syndrome; Obesity; Renin | 2008 |
Molecular and clinical investigations in patients with low-renin hypertension.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Diuretics; Down-Regulation; Drug Resistance; D | 2009 |
Mineralocorticoid antagonism and cardiac hypertrophy.
Topics: Aldosterone; Antihypertensive Agents; Cardiomegaly; Fibrosis; Humans; Hyperaldosteronism; Hypertensi | 2008 |
Obesity, sleep apnea, aldosterone, and hypertension.
Topics: Aldosterone; Humans; Hypertension; Metabolic Syndrome; Mineralocorticoid Receptor Antagonists; Obesi | 2008 |
Circulating endothelial progenitor cells in cardiovascular disorders.
Topics: Acute Coronary Syndrome; Aldosterone; Animals; Apoptosis; Cardiovascular Diseases; Diabetes Mellitus | 2008 |
Altered corticosteroid biosynthesis in essential hypertension: A digenic phenomenon.
Topics: Aldosterone; Blood Pressure; Cytochrome P-450 CYP11B2; Humans; Hypertension; Polymorphism, Genetic; | 2009 |
[Primary aldosteronism].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Renin; Renin-Angiotensin Syst | 2008 |
Aldosterone as an independent factor in cerebrovascular damage.
Topics: Aldosterone; Animals; Blood Pressure; Cerebrovascular Disorders; Disease Models, Animal; Humans; Hyp | 2008 |
Aldosterone and cardiovascular disease.
Topics: Adrenalectomy; Aldosterone; Animals; Antihypertensive Agents; Cardiovascular Agents; Cardiovascular | 2009 |
Reconsidering the roles of the mineralocorticoid receptor.
Topics: Aldosterone; Blood Pressure; Heart Failure; Humans; Hydrocortisone; Hypertension; Mineralocorticoid | 2009 |
[Kidney and hypertension].
Topics: Aldosterone; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Kidney Tubules; Oxidative Str | 2009 |
[Primary hyperaldosteronisms: from diagnosis to treatment].
Topics: Adrenal Cortex Function Tests; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Antihypertensive | 2009 |
Interaction of aldosterone and extracellular volume in the pathogenesis of obesity-associated kidney disease: a narrative review.
Topics: Aldosterone; Animals; Diabetes Complications; Humans; Hypertension; Insulin Resistance; Kidney; Kidn | 2009 |
Effects of eplerenone, a selective mineralocorticoid receptor antagonist, on clinical and experimental salt-sensitive hypertension.
Topics: Aldosterone; Animals; Disease Models, Animal; Eplerenone; Humans; Hypertension; Mineralocorticoid Re | 2009 |
Investigating hypertension in a young person.
Topics: Adult; Aldosterone; Humans; Hypertension; Kidney Diseases; Male; Referral and Consultation; Renin; U | 2009 |
Resistant hypertension: who and how to evaluate.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Humans; Hyperaldosteron | 2009 |
Narrative review: the emerging clinical implications of the role of aldosterone in the metabolic syndrome and resistant hypertension.
Topics: Aldosterone; Cardiovascular Diseases; Endothelium, Vascular; Humans; Hypertension; Insulin Resistanc | 2009 |
Aldosterone-receptor antagonism in hypertension.
Topics: Albuminuria; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Arrhythmias, Cardiac; D | 2009 |
Mineralocorticoid receptor activation in obesity hypertension.
Topics: Aldosterone; Animals; Biological Evolution; Humans; Hypertension; Ligands; Metabolic Syndrome; Miner | 2009 |
[Development of hypertension and RAAS].
Topics: Aldosterone; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Humans; Hypertension; Peptid | 2009 |
[The renin-angiotensin system].
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme | 2009 |
The role of 11β-hydroxysteroid dehydrogenase type 2 in human hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Blood Pressure; Colon; Corticoste | 2010 |
Aldosterone and arterial hypertension.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Blood Vessels; Brain; Cytochrome P-45 | 2010 |
Aliskiren: a new inhibitor of renin-angiotensin aldosterone system activity.
Topics: Aldosterone; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibito | 2009 |
Aldosterone, sodium, and hypertension: lessons from torcetrapib?
Topics: Aldosterone; Animals; Anticholesteremic Agents; Cholesterol Ester Transfer Proteins; Humans; Hyperch | 2010 |
Aldosterone in uremia - beyond blood pressure.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Endothelial Cells; Endothelium, Vascular; | 2010 |
Mineralocorticoid receptors, salt-sensitive hypertension, and metabolic syndrome.
Topics: Aldosterone; Animals; Humans; Hypertension; Metabolic Syndrome; Rats; Rats, Inbred Dahl; Receptors, | 2010 |
The central role of the brain aldosterone-"ouabain" pathway in salt-sensitive hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Choroid Plexus; Ependyma; Epithelial Sodium Channels; Humans; | 2010 |
Aldosterone renin ratio in patients with resistant hypertension.
Topics: Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Predictive Value of Tests; Renin | 2010 |
Midkine regulation of the renin-angiotensin system.
Topics: Acetylcholinesterase; Acute Kidney Injury; Aldosterone; Angiotensin II; Animals; Central Nervous Sys | 2010 |
Hypertension in women: the role of progesterone and aldosterone.
Topics: Aged; Aldosterone; Androstenes; Animals; Cardiovascular Diseases; Diet, Sodium-Restricted; Estradiol | 2010 |
Aldosterone: role in edematous disorders, hypertension, chronic renal failure, and metabolic syndrome.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Drug Resistance; Dru | 2010 |
Epithelial Na+ channel (ENaC), hormones, and hypertension.
Topics: Aldosterone; Animals; Antihypertensive Agents; Epithelial Sodium Channels; Genomics; Hormones; Human | 2010 |
Drug mechanisms to help in managing resistant hypertension in obesity.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Life Style; Mineralocort | 2010 |
Activation of the aldosterone/mineralocorticoid receptor system in chronic kidney disease and metabolic syndrome.
Topics: Aldosterone; Animals; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Humans; Hypertensi | 2010 |
Mineralocorticoid receptor antagonists and the metabolic syndrome.
Topics: Aldosterone; Antihypertensive Agents; Eplerenone; Humans; Hypertension; Inflammation; Insulin Resist | 2010 |
The epithelial sodium channel and the control of sodium balance.
Topics: Aldosterone; Animals; Blood Pressure; Epithelial Sodium Channels; Humans; Hypertension; Nephrons; Re | 2010 |
Role of epithelial sodium channels and their regulators in hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Epithelial Sodium Channels; Humans; Hypertension; Mutation; Ne | 2010 |
Aldosterone, hypertension and heart failure: insights from clinical trials.
Topics: Aldosterone; Animals; Anticholesteremic Agents; Atorvastatin; Clinical Trials as Topic; Dihydrotesto | 2010 |
A systemic review of the relationship between aldosterone synthase - 344 C/T polymorphism and hypertension in Han.
Topics: Aldosterone; China; Female; Genetic Predisposition to Disease; Humans; Hypertension; Male; Polymorph | 2010 |
Prevalence and diagnosis of primary aldosteronism.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Blood Chemical Analysis; Blood Pressure Monitoring, Ambu | 2010 |
Cardiovascular and renal damage in primary aldosteronism: outcomes after treatment.
Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Cardiovascular System; Humans; Hyperaldosteroni | 2010 |
Roles of bone morphogenetic protein-6 in aldosterone regulation by adrenocortical cells.
Topics: Adrenal Cortex; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Bone Morphogenetic Protein 6; | 2010 |
Endogenous ouabain: a link between sodium intake and hypertension.
Topics: Aldosterone; Diet; Humans; Hypertension; Nutritional Status; Ouabain; Receptors, Cell Surface; Risk | 2011 |
Role of genetic variation in regulation of aldosterone biosynthesis.
Topics: Aldosterone; Animals; Cardiovascular Diseases; Cytochrome P-450 CYP11B2; Genetic Variation; Humans; | 2011 |
The kidneys and aldosterone/mineralocorticoid receptor system in salt-sensitive hypertension.
Topics: Aldosterone; Humans; Hypertension; Kidney; Receptors, Mineralocorticoid; Signal Transduction; Sodium | 2011 |
Hypertension due to loss of clock: novel insight from the molecular analysis of Cry1/Cry2-deleted mice.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Biological Clocks; Circadian Rhythm; CLOCK Pr | 2011 |
Mineralocorticoid actions in the brain and hypertension.
Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Brain; Cerebrospinal Fluid; Cytochrome P-450 C | 2011 |
Antihypertensive therapy for patients with obstructive sleep apnea.
Topics: Aldosterone; Antihypertensive Agents; Continuous Positive Airway Pressure; Humans; Hypertension; Inc | 2011 |
Antihypertensive therapy for patients with obstructive sleep apnea.
Topics: Aldosterone; Antihypertensive Agents; Continuous Positive Airway Pressure; Humans; Hypertension; Inc | 2011 |
Antihypertensive therapy for patients with obstructive sleep apnea.
Topics: Aldosterone; Antihypertensive Agents; Continuous Positive Airway Pressure; Humans; Hypertension; Inc | 2011 |
Antihypertensive therapy for patients with obstructive sleep apnea.
Topics: Aldosterone; Antihypertensive Agents; Continuous Positive Airway Pressure; Humans; Hypertension; Inc | 2011 |
Aldosterone, hypertension, and beyond.
Topics: Aldosterone; Epigenomics; Epithelial Sodium Channels; Humans; Hyperaldosteronism; Hypertension; Hypo | 2011 |
Mineralocorticoid receptor blockade in chronic kidney disease.
Topics: Aldosterone; Diabetes Mellitus; Humans; Hypertension; Inflammation; Kidney Failure, Chronic; Mineral | 2011 |
Envoi.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2011 |
Role of mineralocorticoid action in the brain in salt-sensitive hypertension.
Topics: Aldosterone; Animals; Brain; Central Nervous System; Humans; Hypertension; Ligands; Mineralocorticoi | 2012 |
[Non-steroidal anti-inflammatory drugs and risk of stroke in older patients: current controversies and research directions].
Topics: Age Factors; Aged; Aged, 80 and over; Aldosterone; Anti-Inflammatory Agents, Non-Steroidal; Atherosc | 2011 |
Resistant hypertension, obstructive sleep apnoea and aldosterone.
Topics: Airway Resistance; Aldosterone; Antihypertensive Agents; Blood Pressure; Comorbidity; Continuous Pos | 2012 |
Mutations in KCNJ5 gene cause hyperaldosteronism.
Topics: Adenoma; Aldosterone; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Humans; Hype | 2011 |
Luminal nucleotides are tonic inhibitors of renal tubular transport.
Topics: Adenosine Triphosphate; Aldosterone; Animals; Blood Pressure; Cilia; Connexins; Epithelial Cells; Hu | 2011 |
Role of BK channels in hypertension and potassium secretion.
Topics: Aldosterone; Animals; Blood Pressure; Humans; Hypertension; Ion Transport; Kidney Tubules; Large-Con | 2011 |
[Renin-angiotensin-aldosteron system: evolution of views from renin discovery to nowadays. Perspectives of therapeutic block].
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Humans; Hypertension; Mineraloc | 2011 |
Arterial hypertension and thyroid disorders: what is important to know in clinical practice?
Topics: Adrenergic beta-Antagonists; Aldosterone; Animals; Antihypertensive Agents; Calcium Channel Blockers | 2011 |
Emerging drugs which target the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Clinical Trials as Topic; Drug Design; Drugs, | 2011 |
Regulation and dysregulation of epithelial Na+ channels.
Topics: Aldosterone; Animals; Epithelial Sodium Channels; Extracellular Signal-Regulated MAP Kinases; Gene E | 2012 |
Effects of low-sodium diet vs. high-sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride (Cochrane Review).
Topics: Adult; Aged; Aldosterone; Asian People; Black People; Blood Pressure; Catecholamines; Cholesterol; D | 2012 |
Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride.
Topics: Aldosterone; Asian People; Black People; Blood Pressure; Catecholamines; Cholesterol; Diet, Sodium-R | 2011 |
Primary aldosteronism: who should be screened?
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Practice Guidelines as Topic | 2012 |
[Bone and calcium update; research of calcium metabolism on cardiovascular system update. Calcium channel blocker update].
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Calcium Channels; C | 2011 |
M-atrial natriuretic peptide: a novel antihypertensive protein therapy.
Topics: Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Biological Availability; Blood Pres | 2012 |
Prevalence of primary aldosteronism in patient's cohorts and in population-based studies--a review of the current literature.
Topics: Aldosterone; Cohort Studies; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Population Gr | 2012 |
Intrinsic control of sodium excretion in the distal nephron by inhibitory purinergic regulation of the epithelial Na(+) channel.
Topics: Aldosterone; Animals; Biological Transport; Blood Pressure; Epithelial Sodium Channels; Humans; Hype | 2012 |
Inflammation in hypertension: current therapeutic approaches.
Topics: Adipose Tissue; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; Cell Adhe | 2011 |
Extrarenal effects of aldosterone.
Topics: Aldosterone; Endothelium, Vascular; Heart; Humans; Hypertension; Inflammation; Metabolic Syndrome; M | 2012 |
Mineralocorticoid receptor-associated hypertension and its organ damage: clinical relevance for resistant hypertension.
Topics: Aldosterone; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hypertension; Receptors, Mine | 2012 |
[Mechanisms responsible for the renoprotective effects of renin-angiotensin inhibitors].
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Humans; Hypertension; | 2012 |
Resistant hypertension and aldosterone: an update.
Topics: Aldosterone; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Hyperaldosteronis | 2012 |
Aldosterone, oxidative stress, and NF-κB activation in hypertension-related cardiovascular and renal diseases.
Topics: Aldosterone; Animals; Cardiovascular Diseases; Disease Models, Animal; Heart Failure; Humans; Hypera | 2012 |
Pathophysiology of salt sensitivity hypertension.
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Kidney; Protein Serine-Threonine Kinases; rac1 GT | 2012 |
Salt, aldosterone and hypertension.
Topics: Aldosterone; Animals; Appetite; Cardiovascular Diseases; Humans; Hyperaldosteronism; Hypertension; K | 2013 |
Integrating genetics and genomics in primary aldosteronism.
Topics: Aldosterone; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Genomics; Humans; Hyperaldost | 2012 |
The ubiquitous mineralocorticoid receptor: clinical implications.
Topics: Aldosterone; Cardiovascular Diseases; Glucocorticoids; Humans; Hypertension; Mineralocorticoid Recep | 2012 |
Circadian clock-deficient mice as a tool for exploring disease etiology.
Topics: Aldosterone; Animals; Circadian Clocks; Circadian Rhythm; Cryptochromes; Diabetes Mellitus; Humans; | 2012 |
Aldosterone synthase inhibition in humans.
Topics: Aldosterone; Antihypertensive Agents; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Humans; Hypertens | 2013 |
[Update on endocrine hypertension].
Topics: Adrenal Gland Neoplasms; Adrenocortical Adenoma; Aldosterone; Cardiovascular Diseases; Endocrine Sys | 2012 |
Effects of angiotensin II on kinase-mediated sodium and potassium transport in the distal nephron.
Topics: Aldosterone; Angiotensin II; Animals; Epithelial Sodium Channels; Humans; Hyperkalemia; Hypertension | 2013 |
[Primay hyperaldosteronism--diagnostic and treatment].
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocortical Adenoma; A | 2012 |
Vascular actions of aldosterone.
Topics: Adipocytes; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Vessels; Cardiovasc | 2013 |
[Resistant hypertension].
Topics: Age Factors; Aldosterone; Coronary Vasospasm; Disease Management; Diuretics; Humans; Hyperaldosteron | 2012 |
Aldosterone and the risk of hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Renin | 2013 |
Mineralocorticoid receptors and pathophysiological roles for aldosterone in the cardiovascular system.
Topics: Aldosterone; Animals; Cardiomegaly; Cardiovascular System; Heart Failure; Humans; Hyperaldosteronism | 2002 |
[Aldosterone and cardiovascular diseases, more than water and salt retention].
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Body Water; Cardiovascular Di | 2002 |
New genetic insights in familial hyperaldosteronism.
Topics: Adrenal Cortex Diseases; Aldosterone; Chromosomes, Human, Pair 7; Cytochrome P-450 CYP11B2; Humans; | 2002 |
Primary aldosteronism: management issues.
Topics: Adrenal Cortex Diseases; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypok | 2002 |
New biology of aldosterone, and experimental studies on the selective aldosterone blocker eplerenone.
Topics: Aldosterone; Animals; Cardiomegaly; Clinical Trials as Topic; Desoxycorticosterone; Eplerenone; Fibr | 2002 |
Clinical implications of aldosterone blockade.
Topics: Aldosterone; Antihypertensive Agents; Black People; Blood Pressure; Cardiovascular Diseases; Clinica | 2002 |
The role of aldosterone receptor blockade in the management of cardiovascular disease.
Topics: Aldosterone; Animals; Cardiovascular Diseases; Eplerenone; Heart Failure; Humans; Hypertension; Mine | 2002 |
Local cardiac renin-angiotensin system: hypertension and cardiac failure.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically | 2002 |
Aldosterone-induced cardiac damage: focus on blood pressure independent effects.
Topics: Aldosterone; Animals; Blood Pressure; Cardiomyopathies; Heart Failure; Hyperaldosteronism; Hypertens | 2003 |
Aldosterone: a risk factor for vascular disease.
Topics: Aldosterone; Animals; Arteries; Fibrosis; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoi | 2003 |
Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglyceride.
Topics: Aldosterone; Blood Pressure; Catecholamines; Cholesterol; Diet, Sodium-Restricted; Humans; Hypertens | 2003 |
Essential hypertension and left ventricular hypertrophy in cardiovascular disease: beyond overactivity of the renin-angiotensin-aldosterone-sodium system.
Topics: Aldosterone; Animals; Cardiovascular Diseases; Humans; Hypertension; Hypertrophy, Left Ventricular; | 2003 |
Eplerenone.
Topics: Aldosterone; Antihypertensive Agents; Clinical Trials as Topic; Drug Approval; Eplerenone; Humans; H | 2003 |
Aldosterone and specific aldosterone receptor antagonists in hypertension and cardiovascular disease.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Diseases; Endothelium | 2003 |
Is altered adrenal steroid biosynthesis a key intermediate phenotype in hypertension?
Topics: Adrenal Glands; Aldosterone; Cytochrome P-450 CYP11B2; Humans; Hyperaldosteronism; Hypertension; Phe | 2003 |
Negative regulators of sodium transport in the kidney: key factors in understanding salt-sensitive hypertension?
Topics: Aldosterone; Animals; Biological Transport; Blood Pressure; Humans; Hypertension; Hypotension; Kidne | 2003 |
[Monogenic hypertension].
Topics: Adolescent; Adult; Aldosterone; Child; Female; Genes, Dominant; Genotype; Humans; Hyperaldosteronism | 2003 |
Eplerenone: cardiovascular protection.
Topics: Aldosterone; Animals; Cardiovascular Diseases; Cardiovascular System; Disease Models, Animal; Eplere | 2003 |
[Role of ion channels of kidney in water-electrolyte metabolism].
Topics: Aldosterone; Alkalosis; Animals; Bartter Syndrome; Chloride Channels; Humans; Hyperaldosteronism; Hy | 2003 |
Forms of mineralocorticoid hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; | 2003 |
Aldosterone breakthrough during angiotensin-converting enzyme inhibitor therapy.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Clinical Trials as Topic; Diu | 2003 |
[Primary hyperaldosteronism].
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Antihypertensive Agent | 2003 |
Aldosterone receptor antagonists for hypertension: what do they offer?
Topics: Aldosterone; Clinical Trials as Topic; Diuretics; Eplerenone; Heart Failure; Humans; Hypertension; M | 2003 |
[ALDOSTERONE AND HYPERTENSION].
Topics: Aldosterone; Humans; Hypertension | 1963 |
[THE EFFECT OF POSTURAL CHANGES ON THE PHYSIOLOGICAL FUNCTION IN MAN].
Topics: Aldosterone; Cardiovascular System; Epinephrine; Hexamethonium Compounds; Humans; Hypertension; Hypo | 1963 |
[DRUGS INHIBITING ALDOSTERONE SECRETION AND ALDOSTERONE ANTAGONISTS].
Topics: Aldosterone; Edema; Heparinoids; Hypertension; Ketones; Metyrapone; Mineralocorticoid Receptor Antag | 1963 |
[ANGIOTENSIN AND ALDOSTERONE SECRETION].
Topics: Aldosterone; Angiotensins; Biological Transport; Chemical Phenomena; Chemistry; Hypertension; Pharma | 1963 |
CHEMISTRY AND THERAPY OF MALIGNANT HYPERTENSION.
Topics: Aldosterone; Angiotensins; Antihypertensive Agents; Blood Vessels; Cushing Syndrome; Glomerulonephri | 1963 |
MECHANISMS IN ESSENTIAL HYPERTENSION.
Topics: Aldosterone; Angiotensins; Catecholamines; Essential Hypertension; Guanethidine; Hypertension; Miner | 1964 |
SYSTEMIC CIRCULATION.
Topics: Aldosterone; Angiotensins; Blood Circulation; Blood Vessels; Blood Viscosity; Blood Volume; Blood Vo | 1964 |
ALDOSTERONISM.
Topics: Aldosterone; Diagnosis, Differential; Diuretics; Humans; Hyperaldosteronism; Hypertension; Kidney Di | 1964 |
ALDOSTERONE AND ANGIOTENSIN. INTERRELATIONSHIPS IN NORMAL AND DISEASED STATES.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensins; Desoxycorticosterone; Digoxin; Dogs; Heart F | 1964 |
ALDOSTERONE: ITS BIOCHEMISTRY AND PHYSIOLOGY.
Topics: Aldosterone; Angiotensins; Biochemical Phenomena; Biochemistry; Blood; Edema; Female; Homeostasis; H | 1964 |
[METABOLIC DATA ON HYPERTENSION (ESSENTIAL HYPERTENSION)].
Topics: Adrenal Glands; Aldosterone; Angiotensins; Arteriosclerosis; Autonomic Nervous System Diseases; Cate | 1964 |
ALDOSTERONE IN CLINICAL MEDICINE.
Topics: Aldosterone; Blood Volume; Body Weight; Desoxycorticosterone; Dexamethasone; Diuretics; Drug Therapy | 1964 |
RECENT ADVANCES IN HYPERTENSION.
Topics: Aldosterone; Angiotensins; Blood Pressure; Cardiac Output; Hypertension; Hypertension, Renal; Kidney | 1964 |
[PHYSIOPATHOLOGY OF ARTERIAL HYPERTENSION. ROLE OF ANGIOTENSIN AND ALDOSTERONE SECRETION].
Topics: Adrenal Glands; Aldosterone; Angiotensins; Biochemical Phenomena; Biochemistry; Hyperaldosteronism; | 1964 |
[NEW DATA ON THE ETIOPATHOGENESIS OF ESSENTIAL ARTERIAL HYPERTENSION].
Topics: Aldosterone; Electrolytes; Essential Hypertension; Humans; Hypertension; Metabolism | 1965 |
Aldosterone blockade in patients with systolic left ventricular dysfunction.
Topics: Aldosterone; Eplerenone; Forecasting; Heart Failure; Humans; Hypercholesterolemia; Hypertension; Mal | 2003 |
Aldosterone receptor antagonists: biology and novel therapeutical applications.
Topics: Aldosterone; Heart Failure; Hirsutism; Humans; Hyperaldosteronism; Hypertension; Liver Cirrhosis; Mi | 2003 |
Primary aldosteronism.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Diagnosis, Differential; Humans; Hyperaldoster | 2003 |
[The aldosterone to Renin ratio in secondary hypertension].
Topics: Adrenalectomy; Adult; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension | 2003 |
A neuroendocrine-immune interface. The immunostimulatory state of aldosteronism.
Topics: Aldosterone; Antioxidants; Cytokines; Endomyocardial Fibrosis; Heart Failure; Humans; Hyperaldostero | 2003 |
[Rational diagnostic approach in hypertension].
Topics: Adrenal Gland Neoplasms; Aldosterone; Angiography; Cushing Syndrome; Diabetic Nephropathies; Diagnos | 2003 |
Obesity and hypertension.
Topics: Adipose Tissue; Aldosterone; Body Mass Index; Cardiovascular System; Genetic Predisposition to Disea | 2003 |
Hypertension and obesity.
Topics: Adipose Tissue; Aldosterone; Animals; Body Mass Index; Humans; Hypertension; Inflammation; Insulin R | 2004 |
Hypertension and obesity.
Topics: Adipose Tissue; Aldosterone; Animals; Body Mass Index; Humans; Hypertension; Inflammation; Insulin R | 2004 |
Hypertension and obesity.
Topics: Adipose Tissue; Aldosterone; Animals; Body Mass Index; Humans; Hypertension; Inflammation; Insulin R | 2004 |
Hypertension and obesity.
Topics: Adipose Tissue; Aldosterone; Animals; Body Mass Index; Humans; Hypertension; Inflammation; Insulin R | 2004 |
Fibrosis in hypertensive heart disease: role of the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Collagen; Fibrosis; | 2004 |
Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglyceride.
Topics: Aldosterone; Blood Pressure; Catecholamines; Cholesterol; Diet, Sodium-Restricted; Humans; Hypertens | 2004 |
[Significance of aldosterone antagonist therapy].
Topics: Aldosterone; Cardiovascular Diseases; Clinical Trials as Topic; Dose-Response Relationship, Drug; Dr | 2004 |
Trends in the prevalence of primary aldosteronism, aldosterone-producing adenomas, and surgically correctable aldosterone-dependent hypertension.
Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Remission Induction | 2004 |
Evolving role of aldosterone blockers alone and in combination with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers in hypertension management: a review of mechanistic and clinical data.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bloo | 2004 |
Pathogenesis of structural vascular changes in hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Obesity; Sodium Chloride | 2004 |
Genetics of primary aldosteronism.
Topics: Aldosterone; Cytochrome P-450 CYP11B2; Gene Expression Regulation; Genetic Variation; Genetics; Huma | 2004 |
Aldosterone and aldosterone antagonism in systemic hypertension.
Topics: Aldosterone; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hypertension; Mineralocortico | 2004 |
Regulation of epithelial ion transport by aldosterone through changes in gene expression.
Topics: Aldosterone; Anti-Inflammatory Agents; Biological Transport, Active; Cortisone; Epithelial Cells; Ex | 2004 |
Aldosterone target organ protection by eplerenone.
Topics: Aldosterone; Blood Vessels; Brain; Clinical Trials as Topic; Eplerenone; Heart Failure; Humans; Hype | 2004 |
The impact of polymorphisms in the gene encoding aldosterone synthase (CYP11B2) on steroid synthesis and blood pressure regulation.
Topics: Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Cortodoxone; Cytochrome P-450 CYP11B2; Gen | 2004 |
[Hypertension secondary to primary aldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Diagnosis, Di | 2004 |
Brain mineralocorticoid receptors: orchestrators of hypertension and end-organ disease.
Topics: Aldosterone; Brain; Disease; Heart; Humans; Hypertension; Kidney; Receptors, Mineralocorticoid | 2004 |
Mechanisms of obesity-related hypertension.
Topics: Adipose Tissue; Adrenal Glands; Aldosterone; Fatty Acids; Humans; Hypertension; Hypothalamus; Liver; | 2004 |
Role of aldosterone blockade in the management of hypertension and cardiovascular disease.
Topics: Aldosterone; Animals; Heart Failure; Humans; Hypertension; Kidney Diseases; Mineralocorticoid Recept | 2004 |
Mineralocorticoid receptor antagonists and hypertension: is there a rationale?
Topics: Albuminuria; Aldosterone; Animals; Drug Therapy, Combination; Eplerenone; Humans; Hyperkalemia; Hype | 2004 |
Effect of longer-term modest salt reduction on blood pressure.
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Lipids; Norepinephrine; Randomized Controlled Tri | 2004 |
Effect of longer-term modest salt reduction on blood pressure.
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Lipids; Norepinephrine; Randomized Controlled Tri | 2004 |
Effect of longer-term modest salt reduction on blood pressure.
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Lipids; Norepinephrine; Randomized Controlled Tri | 2004 |
Effect of longer-term modest salt reduction on blood pressure.
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Lipids; Norepinephrine; Randomized Controlled Tri | 2004 |
Capsaicin sensitive-sensory nerves and blood pressure regulation.
Topics: Aldosterone; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Capsaicin; | 2003 |
[Diagnosis and treatment of primary hyperaldosteronism].
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Chronic Disease; Diagnosis, Differential; Hum | 2004 |
[Renin-angiotensin-aldosterone system and natriuretic peptide system--reference to cardiovascular diseases].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiovascular Diseases; Drug Design; Heart Fa | 2004 |
Arterial stiffness and the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Arteries; Elasticity; Humans; Hypertension; Renin-Angiotensin System | 2004 |
Obesity-associated hypertension: new insights into mechanisms.
Topics: Adiponectin; Aldosterone; Animals; Appetite; Endothelium, Vascular; Energy Metabolism; Ghrelin; Huma | 2005 |
Plasma renin and aldosterone measurements in low renin hypertensive states.
Topics: Aldosterone; Blood Chemical Analysis; Humans; Hypertension; Renin; Sensitivity and Specificity | 2005 |
Aldosterone as a cardiovascular risk factor.
Topics: Aldosterone; Animals; Cardiac Output, Low; Cardiovascular Diseases; Humans; Hypertension; Mineraloco | 2005 |
Genetics of human hypertension.
Topics: Aldosterone; Genetic Linkage; Humans; Hypertension; Polymorphism, Genetic; Renin-Angiotensin System | 2005 |
[Blockade of renin-angiotensin system and aldosterone breakthrough].
Topics: Aldosterone; Animals; Humans; Hypertension; Renin-Angiotensin System | 2005 |
Pleiotropic actions of aldosterone and the effects of eplerenone, a selective mineralocorticoid receptor antagonist.
Topics: Aldosterone; Animals; Drug Interactions; Eplerenone; Humans; Hypertension; Mineralocorticoid Recepto | 2004 |
Mineralocorticoid resistance.
Topics: Aldosterone; Genes, Dominant; Genes, Recessive; Genotype; Humans; Hypertension; Kidney; Mineralocort | 2005 |
Cardiovascular effects of aldosterone.
Topics: Aldosterone; Animals; Cardiovascular Diseases; Heart Failure; Humans; Hypertension; Mineralocorticoi | 2005 |
Aldosterone receptor antagonists: biology and novel therapeutic applications.
Topics: Aldosterone; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Ant | 2005 |
[Hypertension due to primary aldosteronism].
Topics: Aldosterone; Decision Trees; Humans; Hyperaldosteronism; Hypertension | 2005 |
[Aldosterone blockade in essential hypertension].
Topics: Aldosterone; Fibrosis; Humans; Hypertension; Inflammation; Mineralocorticoid Receptor Antagonists | 2005 |
Role of cardiovascular aldosterone in hypertension.
Topics: Aldosterone; Animals; Cardiovascular System; Epithelial Cells; Humans; Hypertension | 2005 |
Antihypertensive therapy: role of aldosterone antagonists.
Topics: Aldosterone; Animals; Antihypertensive Agents; Humans; Hypertension; Mineralocorticoid Receptor Anta | 2005 |
[Roll of aldosterone in pathogenesis of kidney disorders].
Topics: Aldosterone; Animals; Body Water; Disease Models, Animal; Eplerenone; Humans; Hypertension; Kidney D | 2005 |
Molecular mechanisms of mineralocorticoid receptor antagonism by eplerenone.
Topics: Aldosterone; Animals; Eplerenone; Heart Failure; Hypertension; Ligands; Mineralocorticoid Receptor A | 2005 |
Treatment of resistant hypertension.
Topics: Aldosterone; Algorithms; Antihypertensive Agents; Drug Resistance; Hemodynamics; Humans; Hypertensio | 2005 |
Miscellaneous endocrine causes of hypertension.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Biomarkers; Humans; Hyperaldoster | 2005 |
Mineralocorticoid-stimulating activity of adipose tissue.
Topics: Adipocytes; Adipose Tissue; Aldosterone; Blood Pressure; Humans; Hypertension; Mineralocorticoids; O | 2005 |
Aldosterone--a hormone of cardiovascular adaptation and maladaptation.
Topics: Aldosterone; Blood Pressure; Cardiovascular Diseases; Electrolytes; Homeostasis; Humans; Hypertensio | 2006 |
[Molecular mechanism in biological transport in the kidney: Na+/K(+)-ATPase].
Topics: Aldosterone; Biological Transport; Calmodulin-Binding Proteins; Catecholamines; Hypertension; Insuli | 2006 |
Mineralocorticoid receptor blockade in the protection of target organ damage.
Topics: Aldosterone; Animals; Brain; Brain Diseases; Cardiovascular Diseases; Eplerenone; Heart; Humans; Hyp | 2006 |
The role of aldosterone in renal sodium transport.
Topics: Aldosterone; Biological Transport; Blood Pressure; Humans; Hypertension; Nephrons; Sodium | 2006 |
The pharmacological treatment of primary aldosteronism.
Topics: Aldosterone; Amiloride; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combinatio | 2006 |
Inherited sodium avid states.
Topics: Aldosterone; Genetic Predisposition to Disease; Humans; Hypertension; Nephrons; Renin; Sodium; Sodiu | 2006 |
Optimal use and interpretation of the aldosterone renin ratio to detect aldosterone excess in hypertension.
Topics: Aldosterone; Antihypertensive Agents; Captopril; Humans; Hyperaldosteronism; Hypertension; Renin; Se | 2006 |
Role of the renin-angiotensin-aldosterone system in vascular remodeling and inflammation: a clinical review.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme | 2006 |
[Regulation by vasopressin of NaCl absorption in the renal collecting duct].
Topics: Absorption; Aldosterone; Amiloride; Animals; Cells, Cultured; Chlorides; Cystic Fibrosis Transmembra | 2005 |
The renal epithelial sodium channel: genetic heterogeneity and implications for the treatment of high blood pressure.
Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Endosomal Sorting Complexes Required for Transport; | 2006 |
[Prostasin].
Topics: Aldosterone; Amyloid beta-Protein Precursor; Animals; Benzamidines; Epithelial Sodium Channels; Guan | 2006 |
[Nitric oxide].
Topics: Adiponectin; Aldosterone; Animals; Arginine; Blood Pressure; Cardiovascular Diseases; Endothelium, V | 2006 |
Hypertension and diabetes: role of the renin-angiotensin system.
Topics: Aldosterone; Antihypertensive Agents; Cardiovascular Diseases; Diabetes Complications; Diabetes Mell | 2006 |
Screening for primary aldosteronism.
Topics: Aldosterone; Algorithms; Humans; Hyperaldosteronism; Hypertension; Potassium; Prevalence; Renin | 2006 |
Surgically correctable hypertension caused by primary aldosteronism.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Algorit | 2006 |
Incidentally discovered masses in hypertensive patients.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cushing Syndrome; Diagnostic Imaging; Humans; Hyperte | 2006 |
[Normokalemic primary hyperaldosteronism].
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hype | 2006 |
Association of the C-344T aldosterone synthase gene variant with essential hypertension: a meta-analysis.
Topics: Aldosterone; Blood Pressure; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Cytochro | 2007 |
Hypertension and the expanding role of aldosterone.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Humans; Hypertension | 2006 |
Aldosterone breakthrough during RAS blockade: a role for endothelins and their antagonists?
Topics: Adrenal Cortex; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme | 2006 |
Primary hyperaldosteronism secondary to unilateral adrenal hyperplasia: an unusual cause of surgically correctable hypertension. A review of 30 cases.
Topics: Adrenal Glands; Aldosterone; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; Male; Mi | 2007 |
Resistant hypertension: prevalence and evolving concepts.
Topics: Aldosterone; Humans; Hypertension; Prevalence; Recurrence; Sleep Apnea, Obstructive; Treatment Failu | 2007 |
Aldosterone and the vasculature: mechanisms mediating resistant hypertension.
Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Endothelium; Humans; Hypertension; Muscle, Sm | 2007 |
[Diagnosis of primary hyperaldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia | 2007 |
[Screening tests and diagnostic examinations of hypertensives for primary aldosteronism].
Topics: Adrenal Cortex Function Tests; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Antihyperten | 2006 |
Genetics of arterial hypertension and hypotension.
Topics: Aldosterone; Blood Pressure; Genetic Predisposition to Disease; Humans; Hydrocortisone; Hypertension | 2007 |
Ca2+ channel subtypes and pharmacology in the kidney.
Topics: Aldosterone; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Calcium Channel Blockers; | 2007 |
Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions.
Topics: Aldosterone; Angiotensin II; Cell Adhesion Molecules; Cytokines; Diabetes Complications; Diabetes Me | 2007 |
Aldosterone excess, hypertension, and chromosome 7p22: evidence continues to mount.
Topics: Aldosterone; Chromosome Mapping; Chromosomes, Human, Pair 7; Genetic Linkage; Humans; Hypertension | 2007 |
Angiotensin II reactivation and aldosterone escape phenomena in renin-angiotensin-aldosterone system blockade: is oral renin inhibition the solution?
Topics: Administration, Oral; Aldosterone; Amides; Angiotensin II; Animals; Antihypertensive Agents; Enzyme | 2007 |
New concepts in adrenal vein sampling for aldosterone in the diagnosis of primary aldosteronism.
Topics: Adrenal Glands; Aldosterone; Blood Pressure; Diagnosis, Differential; Humans; Hyperaldosteronism; Hy | 2007 |
The role of aldosterone in resistant hypertension: implications for pathogenesis and therapy.
Topics: Aldosterone; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Mi | 2007 |
Why are mineralocorticoid receptors so nonselective?
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Blood Pressure; Humans; Hydrocortisone; Hy | 2007 |
The emerging role of ACE2 in physiology and disease.
Topics: Aldosterone; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Diseases; Coronavirus; Female; | 2007 |
A primer on aldosterone for gynecologists/obstetricians.
Topics: Aldosterone; Female; Gynecology; Heart Failure; Humans; Hypertension; Mineralocorticoid Receptor Ant | 2007 |
Drug insight: aldosterone-receptor antagonists in heart failure--the journey continues.
Topics: Aldosterone; Contraindications; Drug Therapy, Combination; Eplerenone; Heart Failure; Humans; Hypert | 2007 |
The role of aldosterone and mineralocorticoid receptors in cardiovascular disease.
Topics: Aldosterone; Animals; Atherosclerosis; Cardiovascular Diseases; Heart Failure; Humans; Hyperaldoster | 2007 |
[Hypertension in postmenopausal women --selected pathomechanisms].
Topics: Age Factors; Aldosterone; Angiotensin II; Blood Pressure; Body Mass Index; Dyslipidemias; Estrogen R | 2006 |
Aldosteronism and hypertension.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Mass | 2006 |
The association of aldosterone with obesity-related hypertension and the metabolic syndrome.
Topics: Adipose Tissue; Aldosterone; Animals; Blood Pressure; Humans; Hypertension; Metabolic Syndrome; Obes | 2007 |
Adrenal causes of hypertension: pheochromocytoma and primary aldosteronism.
Topics: Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Models, Biological; Pheochrom | 2007 |
[Hypertension and metabolic syndrome].
Topics: Aldosterone; Humans; Hypertension; Insulin Resistance; Metabolic Syndrome; Oxidative Stress; Renin-A | 2007 |
Hyperaldosteronism: a commonly occurring underlying feature of essential hypertension and the metabolic syndrome?
Topics: Aldosterone; Black or African American; Humans; Hyperaldosteronism; Hypertension; Insulin Resistance | 2007 |
Aldosterone and refractory hypertension.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Drug Resistance; Humans; Hyperaldosteronism; H | 2007 |
Aldosterone and progression of renal disease.
Topics: Aldosterone; Animals; Disease Progression; Humans; Hypertension; Kidney Diseases; Prorenin Receptor; | 2008 |
Resistant hypertension and aldosteronism.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Bloc | 2007 |
Rapid non-genomic effects of aldosterone on the renal vasculature.
Topics: Aldosterone; Animals; Blood Flow Velocity; Disease Progression; Endothelium, Vascular; Glomerular Fi | 2008 |
Endocrine arterial hypertension: diagnostic approach in clinical practice.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Algorithms; Catecholamines; Cushing Syndrome; Diagnos | 2008 |
Primary aldosteronism, a major form of low renin hypertension: from screening to diagnosis.
Topics: Aldosterone; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Re | 2008 |
Aldosterone and glomerular podocyte injury.
Topics: Aldosterone; Animals; Disease Models, Animal; Humans; Hypertension; Metabolic Syndrome; Oxidative St | 2008 |
Aldosterone and metabolic syndrome: is increased aldosterone in metabolic syndrome patients an additional risk factor?
Topics: Aldosterone; Cardiovascular Diseases; Humans; Hypertension; Lipid Metabolism; Metabolic Syndrome; Ob | 2008 |
Spotlight on HDL-raising therapies: insights from the torcetrapib trials.
Topics: Aldosterone; Anticholesteremic Agents; Blood Pressure; Cardiovascular Diseases; Cholesterol Ester Tr | 2008 |
Aldosterone in salt-sensitive hypertension and metabolic syndrome.
Topics: Aldosterone; Animals; Humans; Hypertension; Metabolic Syndrome; Receptors, Mineralocorticoid; Renin- | 2008 |
The role of adrenal steroidogenesis in arterial hypertension.
Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertensi | 2008 |
[Diagnostic tests for endocrine hypertension].
Topics: Adrenal Cortex Function Tests; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; A | 1984 |
Disorders of the adrenal cortex: their effects on electrolyte metabolism.
Topics: Addison Disease; Adrenal Cortex Diseases; Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; | 1984 |
An overview of the clinical pharmacology of enalapril.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Di | 1984 |
Some aspects of kidney function, the renin-aldosterone system and sympathetic activity in essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Albuminuria; Aldosterone; Catecholamines; Female; Glomerular Fil | 1980 |
Antihypertensive beta-blockade and the renin-angiotensin system.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensins; Animals; Hypertension; Potassium; Renin | 1980 |
Renin-angiotensin-aldosterone and hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensinogen; Angiotensins; Animals; Blood Press | 1980 |
Measurement of the hormones of the renin system in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Blood Volume; | 1981 |
Renin in essential hypertension.
Topics: Adrenergic beta-Antagonists; Age Factors; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme | 1981 |
The effect of adrenergic blockade on potassium concentrations in different conditions.
Topics: Adrenergic beta-Antagonists; Aldosterone; Animals; Epinephrine; Humans; Hypertension; Pindolol; Pota | 1983 |
Adrenergic regulation of renin release and effects on angiotensin and aldosterone.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Animals; Dinoprostone; Dogs; Electric Stim | 1983 |
Hypertension, the adrenal and the kidney: lessons from pharmacologic interruption of the renin-angiotensin system.
Topics: Adrenal Glands; Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Angiotensins; Animals; Blo | 1980 |
Clonidine and the kidney.
Topics: Adrenal Gland Neoplasms; Aldosterone; Antihypertensive Agents; Catecholamines; Clonidine; Humans; Hy | 1980 |
[The renin-angiotensin system. Physiopathological aspects and clinical implications of hypertensive syndromes. A survey].
Topics: Acromegaly; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Cushing Syndrome; Glycoproteins; | 1981 |
Exogenous mineralocorticoid-like disorders.
Topics: Adult; Aldosterone; Animals; Carbenoxolone; Emollients; Female; Fludrocortisone; Fluprednisolone; Gl | 1981 |
Captopril in the treatment of hypertension.
Topics: Aldosterone; Captopril; Drug Eruptions; Hemodynamics; Humans; Hypertension; Hypotension; Physical Ex | 1982 |
Quo vadis basic and clinical chronobiology: promise for health maintenance.
Topics: Adrenal Cortex; Alcoholism; Aldosterone; Biological Clocks; Blood Pressure; Breast Neoplasms; Cardio | 1983 |
The renin system and future trends in management of high blood pressure.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Antihypertensive Agents; Blood | 1980 |
Hypertension of childhood with suppressed renin.
Topics: 18-Hydroxydesoxycorticosterone; 20-alpha-Dihydroprogesterone; Adolescent; Adrenal Cortex; Adrenal Hy | 1980 |
[Pharmacological effects of captopril].
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Bradyk | 1981 |
Angiotensin converting enzyme (ACE) inhibitors.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Capt | 1982 |
Enzymatic disorders and hypertension.
Topics: Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; A | 1981 |
The kinins and prostaglandins in hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Water; Dinoprost; Female; Furos | 1981 |
[Renin-angiotensin-aldosterone function tests].
Topics: Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Desoxycorti | 1982 |
Angiotensin-converting enzyme and its clinical significance--a review.
Topics: Adolescent; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dogs; | 1983 |
Overview: the role of angiotensin-converting enzyme inhibitors in cardiovascular therapy.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dipeptides; Diuretics; Dose-Respon | 1984 |
[Hypertensinogenic steroids].
Topics: Aldosterone; Animals; Blood Pressure; Calcium; Catecholamines; Desoxycorticosterone; Female; Glucoco | 1984 |
[New mineralocorticoids and mineralocorticoid-like steroids].
Topics: Aldosterone; Androstenedione; Animals; Desoxycorticosterone; Female; Humans; Hypertension; Pregnancy | 1984 |
Interaction between the natriuretic effects of renal perfusion pressure and the antinatriuretic effects of angiotensin and aldosterone in control of sodium excretion.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Volume; Hypertension; Inf | 1984 |
The Franz Gross Memorial Lecture. The renin-aldosterone connection: past, present and future.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Animals; Diet, Sodium-Restricted; Dogs; Humans; Hyper | 1984 |
Pathophysiology of hypertension and ischemic heart disease.
Topics: Adult; Aldosterone; Animals; Cardiomegaly; Coronary Circulation; Coronary Disease; Endocardium; Hear | 1980 |
[The catecholamine system].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Catecholamines; Dogs; Drug Interactions; Human | 1982 |
Toward chronobiologic pattern discrimination of the risk of developing breast cancer and other diseases.
Topics: Adolescent; Adult; Age Factors; Aldosterone; Breast Neoplasms; Carbohydrate Metabolism; Circadian Rh | 1982 |
Pathophysiology of the syndrome of hyporeninemic hypoaldosteronism.
Topics: Acidosis; Aged; Aldosterone; Ammonia; Angiotensin II; Bicarbonates; Cations, Monovalent; Extracellul | 1980 |
The renal kallikrein-kinin system.
Topics: Acute Kidney Injury; Aldosterone; Angiotensins; Animals; Blood Pressure; Glomerular Filtration Rate; | 1980 |
Steroid receptors and hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Cardiac Output; Cytosol; Dexamethasone; Drinking; Fludrocortis | 1980 |
Salt balance and long-term blood pressure control.
Topics: Aldosterone; Blood Pressure; Blood Volume; Cardiac Output; Diet; Extracellular Space; Humans; Hypert | 1980 |
[Effect of oral contraceptives on the circulatory system].
Topics: Aldosterone; Angiotensin II; Cardiovascular Diseases; Cerebrovascular Disorders; Contraceptives, Ora | 1980 |
Sodium and hypertension. A review of the role of sodium in pathogenesis and the action of diuretic drugs.
Topics: Age Factors; Aldosterone; Amiloride; Benzothiadiazines; Diuretics; Furosemide; Humans; Hypertension; | 1980 |
Effects of captopril in animal models of hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Animals; Arteries; Blood Pressure; Brady | 1980 |
Primary aldosteronism--a review.
Topics: 18-Hydroxycorticosterone; Adenoma; Adolescent; Adrenal Glands; Adult; Aldosterone; Child; Humans; Hy | 1980 |
Hypertension in pregnancy.
Topics: Aldosterone; Angiotensins; Female; Humans; Hypertension; Kidney; Pre-Eclampsia; Pregnancy; Pregnancy | 1980 |
Sodium and mineralocorticoids in normal pregnancy.
Topics: Aldosterone; Angiotensinogen; Desoxycorticosterone; Diet, Sodium-Restricted; Diuretics; Female; Huma | 1980 |
Regulation of aldosterone secretion in normotensive and hypertensive man.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Humans; Hypertension; Potassiu | 1980 |
Captopril: a preliminary review of its pharmacological properties and therapeutic efficacy.
Topics: Aldosterone; Angiotensin II; Captopril; Drug Interactions; Heart Failure; Hemodynamics; Humans; Hype | 1980 |
The renin-angiotensin system and aldosterone in hypertension: a brief review of some aspects.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Renin | 1981 |
The role of the renin-angiotensin-aldosterone system in circulatory control and hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin | 1981 |
[Essential hypertension, renovascular hypertension and potassium metabolism].
Topics: Aldosterone; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Potassium; Renin | 1981 |
[Primary hyperaldosteronism-current theories].
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia | 1981 |
[Limited usefulness of corticosteroid therapy (author's transl)].
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Arthritis, Rheumatoid; Glucose; Humans; Hypert | 1981 |
Studies on the mechanism of mineralocorticoid-induced hypertension: evidence for the presence of an in-situ mechanism in the arterial wall for a direct action of mineralocorticoids.
Topics: Aldosterone; Animals; Arteries; Cell Nucleus; Chromatin; Corticosterone; Cytosol; Desoxycorticostero | 1981 |
Interactions of renal prostaglandins with the renin-angiotensin system.
Topics: Aldosterone; Animals; Arachidonic Acids; Dogs; Humans; Hypertension; Kidney; Pressoreceptors; Prosta | 1981 |
Pathogenesis of mineralocorticoid hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Animals; Bloo | 1981 |
[Recent medico-social aspects of arterial hypertension].
Topics: Adult; Age Factors; Aged; Aldosterone; Autonomic Nervous System; Blood Pressure Determination; Brady | 1982 |
Renin-angiotensin-aldosterone system for blood pressure and electrolyte homeostasis and its involvement in hypertension, in congestive heart failure and in associated cardiovascular damage (myocardial infarction and stroke).
Topics: Aldosterone; Animals; Blood Pressure; Cardiovascular Diseases; Cerebrovascular Disorders; Electrolyt | 1995 |
The cardiac renin-angiotensin-aldosterone system and hypertensive cardiac hypertrophy.
Topics: Adaptation, Physiological; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; An | 1995 |
[New data on mineralocorticoid hormones. Physiopathological implications].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Receptors, Glucocorticoid; Receptors, Mineral | 1995 |
The promiscuous receptor: a case for the guardian enzyme.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Corticosterone; Humans; Hydroxysteroid | 1995 |
Mineralocorticoid receptors and hypertension.
Topics: Aldosterone; Animals; Epithelium; Heart Diseases; Hypertension; Rats; Receptors, Glucocorticoid; Rec | 1995 |
Pharmacological modulation of cardiac fibroblast function.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomyopathy, Dilated; Collagen; E | 1995 |
Renal parenchymal disease and hypertension.
Topics: Aldosterone; Animals; Blood Proteins; Cardenolides; Digoxin; Endothelins; Humans; Hypertension; Kall | 1995 |
Significance of 19-noraldosterone, a new mineralocorticoid, in clinical and experimental hypertension.
Topics: Aldosterone; Animals; Humans; Hypertension; Rats; Rats, Inbred SHR | 1995 |
Aldosterone-secreting adrenal cortical adenoma in an 11-year-old child and collective review of the literature.
Topics: Adrenocortical Adenoma; Aldosterone; Alkalosis; Child; Female; Humans; Hyperaldosteronism; Hypertens | 1994 |
Recent advances in endothelin research on cardiovascular and endocrine systems.
Topics: Adrenal Glands; Aldosterone; Animals; Cardiovascular Physiological Phenomena; Endothelins; Hemodynam | 1994 |
Type II pseudohypoaldosteronism. Report of a case and review of the literature.
Topics: Aldosterone; Atrial Natriuretic Factor; Female; Humans; Hyperkalemia; Hypertension; Middle Aged; Pot | 1994 |
Developments in the molecular biology of corticosteroid synthesis and action: implications for an understanding of essential hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Aldosterone; Animals; Cortisone; Hum | 1994 |
Apparent mineralocorticoid excess.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Glycyrrhiza; Humans; Hydroxysteroid Dehydrogenas | 1994 |
Control of vascular reactivity in pregnancy: the basis for therapeutic approaches to prevent pregnancy-induced hypertension.
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Metabolic Clearance Rate; Pregnancy; Preg | 1994 |
Glucocorticoid-remediable aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mutation | 1994 |
[The dopaminergic regulation of the renin-angiotensin-aldosterone system. The control of aldosterone secretion (2)].
Topics: Aldosterone; Animals; Dopamine; Humans; Hypertension; Receptors, Dopamine; Renin-Angiotensin System | 1994 |
Calcium antagonism: aldosterone and vascular responses to catecholamines and angiotensin II in man.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Cardiovascular Physiological | 1993 |
The association of aldosterone-producing adrenal adenoma in a patient with autosomal dominant polycystic kidney disease.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hyper | 1994 |
[Age-related changes in the renin-angiotensin-aldosterone system and the sympathetic nervous system in patients with essential hypertension].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Blood Pressure; Catecholamines; Fema | 1993 |
AANA Journal course. 5: Update for nurse anesthetists--essential hypertension, anesthesia, and the kidney.
Topics: Aldosterone; Anesthesia; Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Intraoperative | 1993 |
Fatty acids may regulate aldosterone secretion and mediate some of insulin's effects on blood pressure.
Topics: Aldosterone; Angiotensin II; Animals; Black People; Blood Pressure; Cattle; Cohort Studies; Dogs; Fa | 1993 |
Reduced aldosterone metabolites in hypertension.
Topics: Aldosterone; Animals; Female; Hypertension; Male; Mineralocorticoids; Sodium, Dietary | 1993 |
Conn syndrome in a child, caused by adrenal adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Child; Fatigue; Female; Humans; Hyperaldosteronism; H | 1996 |
Mineralocorticoids, salt, hypertension: effects on the heart.
Topics: Aldosterone; Animals; Cardiomegaly; Fibrosis; Heart; Humans; Hypertension; Hypokalemia; Mineralocort | 1996 |
Aldosterone and its mechanism of action: more questions than answers.
Topics: Aldosterone; Animals; Blood Pressure; Humans; Hydrocortisone; Hypertension; Receptors, Mineralocorti | 1995 |
11 beta-Hydroxysteroid dehydrogenase deficit: a rare cause of arterial Hypertension. Diagnosis and therapeutic approach in two young brothers.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Child; Child, Preschool; Cortisone; Dexamethason | 1996 |
Inherited forms of mineralocorticoid hypertension.
Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Animals; Humans; Hydrocortisone; Hypertension; Mineral | 1996 |
The renin-angiotensin-aldosterone system and the cardiac natriuretic peptides.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiac Output, Low; Central Nervou | 1996 |
Clinical relevance of about-yearly changes in blood pressure and the environment.
Topics: Aldosterone; Blood Pressure; Chronobiology Phenomena; Humans; Hypertension; Melatonin; Models, Cardi | 1996 |
11 beta-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; ACTH Syndrome, Ectopic; Aldosterone; Glycyrrhiza; Humans; Hyd | 1997 |
Mineralocorticoid receptors and glucocorticoid receptors.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Corticosterone; Humans; Hydrocortisone; | 1996 |
Vascular function in OSA.
Topics: Aldosterone; Angiotensin II; Arginine; Atrial Natriuretic Factor; Endothelium; Humans; Hypertension; | 1996 |
[Pathophysiology of left ventricular hypertrophy in arterial hypertension].
Topics: Aldosterone; Cyclic AMP; Growth Substances; Heart; Humans; Hypertension; Hypertrophy, Left Ventricul | 1997 |
[Mineralocorticoid-induced hypertension].
Topics: 17-Hydroxysteroid Dehydrogenases; Adenoma; Aldosterone; Chromosomes, Human, Pair 8; Crossing Over, G | 1997 |
Nonesterified fatty acids in the pathogenesis of hypertension: theory and evidence.
Topics: Aldosterone; Animals; Blood Pressure; Fatty Acids, Nonesterified; Homeostasis; Humans; Hypertension; | 1997 |
Hypertension in autosomal dominant polycystic kidney disease.
Topics: Aldosterone; Humans; Hypertension; Polycystic Kidney, Autosomal Dominant; Renal Circulation; Renin-A | 1997 |
Regulation and role of myocardial collagen matrix remodeling in hypertensive heart disease.
Topics: Adult; Aldosterone; Angiotensin II; Animals; Cells, Cultured; Collagen; Collagenases; Heart; Heart D | 1997 |
Left ventricular anatomy and function in primary aldosteronism and renovascular hypertension.
Topics: Adrenalectomy; Aldosterone; Animals; Heart; Heart Ventricles; Humans; Hyperaldosteronism; Hypertensi | 1997 |
Left ventricular hypertrophy in hypertension: etiology, treatment, and controversies.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Hem | 1998 |
Effects of sodium restriction on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglyceride: a meta-analysis.
Topics: Aldosterone; Blood Pressure; Body Weight; Catecholamines; Cholesterol; Diet, Sodium-Restricted; Horm | 1998 |
[Mineralocorticoids and hypertension].
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Animals; Child; Child, Pres | 1998 |
Liddle's syndrome in an elderly woman.
Topics: Aged; Aldosterone; Alkalosis; Diagnosis, Differential; Diuretics; Female; Humans; Hypernatremia; Hyp | 1998 |
Renin-producing adrenal tumor: report of a case.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Humans; Hypertension; Ma | 1998 |
[The role of neurohormonal mechanisms in the etiopathogenesis of essential hypertension].
Topics: Aldosterone; Angiotensin II; Endothelins; Humans; Hypertension; Neuropeptide Y; Nitric Oxide; Renin; | 1998 |
[The effect of reduced sodium intake on blood pressure, body weight, renin, aldosterone, catecholamines, cholesterol and triglycerides. A meta-analysis].
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Catecholamines; Cholesterol; Diet, Sodium-Res | 1999 |
[Molecular structure of renin-angiotensin-aldosterone system].
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Electrolytes; Gene Expression | 1999 |
[Hypertension and mineralocorticoids. Usefulness of renin and aldosterone measurements].
Topics: Aldosterone; Electrolytes; Humans; Hyperaldosteronism; Hypertension; Hypoaldosteronism; Mineralocort | 1999 |
Interactions between endothelin-1 and the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Animals; Endothelin-1; Humans; Hypertension; Models, Biological; Plasma Volume; Recepto | 1999 |
Aldosterone and the heart: towards a physiological function?
Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Animals; Cytochrome P-450 CYP11B2; Fibrosis; Gene Expre | 1999 |
Steroid dehydrogenase structures, mechanism of action, and disease.
Topics: 17-Hydroxysteroid Dehydrogenases; Aldosterone; Amino Acid Sequence; Animals; Cortisone Reductase; Gl | 2000 |
Beneficial interactions between pharmacological, pathophysiological and hypertension research.
Topics: Aldosterone; Animals; Antihypertensive Agents; Calcium; Humans; Hypertension; Renin-Angiotensin Syst | 1999 |
Mineralocorticoid selectivity: molecular and cellular aspects.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Blood Pressure; Glucocorticoids; Humans | 2000 |
Role of the 11beta-hydroxysteroid dehydrogenase type 2 in blood pressure regulation.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Blood Pressure; Humans; Hydroxysteroid Dehydroge | 2000 |
Aldosterone antagonists in hypertension and heart failure.
Topics: Aldosterone; Animals; Female; Heart Failure; Humans; Hypertension; Male; Mineralocorticoid Receptor | 2000 |
Clinical implications of the ovarian/endometrial renin-angiotensin-aldosterone system.
Topics: Aldosterone; Animals; Endometrium; Female; Humans; Hypertension; Male; Menstrual Cycle; Ovary; Pre-E | 2000 |
Heart-hitting tales of salt and destruction.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cardiovascular Diseases; Humans; Hyperaldosteronism; | 2000 |
Angiotensin II receptor blockers: equal or preferred substitutes for ACE inhibitors?
Topics: Acrylates; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; | 2000 |
Dynamic interactions between integrative physiology and molecular medicine: the key to understand the mechanism of action of aldosterone in the kidney.
Topics: Acid-Base Equilibrium; Aldosterone; Animals; Bicarbonates; Humans; Hypertension; Kidney; Sodium Chlo | 2000 |
Aldosterone-related genetic effects in hypertension.
Topics: Aldosterone; Cytochrome P-450 CYP11B2; Epithelium; Humans; Hyperaldosteronism; Hypertension; Ion Tra | 2000 |
Aldosterone and vascular damage.
Topics: Adrenal Cortex; Aldosterone; Arteries; Autonomic Nervous System; Baroreflex; Body Water; Compliance; | 2000 |
The promise of selective aldosterone receptor antagonists for the treatment of hypertension and congestive heart failure.
Topics: Aldosterone; Animals; Antihypertensive Agents; Eplerenone; Heart Failure; Humans; Hypertension; Mine | 2000 |
[Steroid hormone].
Topics: Aldosterone; Animals; Humans; Hydroxysteroid Dehydrogenases; Hypertension; Mineralocorticoids | 2000 |
Genetic determination of human essential hypertension.
Topics: Aldosterone; Carrier Proteins; Humans; Hydrocortisone; Hypertension; Kallikreins; Kidney; Kinins; Re | 2000 |
Non-genomic actions of aldosterone: role in hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Calcium; Cyclic AMP; Humans; Hypertension; Inositol 1,4,5-Tris | 2001 |
K(+) depletion and the progression of hypertensive disease or heart failure. The pathogenic role of diuretic-induced aldosterone secretion.
Topics: Aldosterone; Animals; Antihypertensive Agents; Benzothiadiazines; Clinical Trials as Topic; Disease | 2001 |
Molecular mechanisms of human hypertension.
Topics: Aldosterone; Animals; Female; Genes, Recessive; Humans; Hypertension; Male; Mineralocorticoids; Mode | 2001 |
Aldosterone as a mediator of progressive renal disease: pathogenetic and clinical implications.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Eplerenone; Humans; Hyper | 2001 |
A review of the medical treatment of primary aldosteronism.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Humans; Hyperaldost | 2001 |
Primary aldosteronism: revival of a syndrome.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mutation; Renin; Syndrome | 2001 |
The spironolactone renaissance.
Topics: Aldosterone; Androgen Antagonists; Angiogenesis Inhibitors; Animals; Clinical Trials as Topic; Colla | 2001 |
The hypertensive patient with hypokalaemia: the search for hyperaldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Magnetic Resonance Angiography; | 2001 |
Aldosterone and the hypertensive kidney: its emerging role as a mediator of progressive renal dysfunction: a paradigm shift.
Topics: Aldosterone; Animals; Disease Progression; Humans; Hypertension; Kidney; Kidney Diseases; Renal Insu | 2001 |
Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit | 2001 |
Pathophysiological effects of aldosterone in cardiovascular tissues.
Topics: Adrenalectomy; Aldosterone; Animals; Cardiovascular Diseases; Cerebral Hemorrhage; Humans; Hypertens | 2001 |
The diagnosis of essential and secondary hypertension in adults.
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Algorithms; Angiography; Blood Pressure Determination; | 2001 |
Hyperaldosteronism: recent concepts, diagnosis, and management.
Topics: Aged; Aldosterone; Diuretics; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; M | 2001 |
Primary aldosteronism: are we diagnosing and operating on too few patients?
Topics: Aldosterone; Diagnostic Techniques, Endocrine; Endocrine Surgical Procedures; Humans; Hyperaldostero | 2001 |
Recent studies with eplerenone, a novel selective aldosterone receptor antagonist.
Topics: Aldosterone; Animals; Cardiovascular System; Clinical Trials as Topic; Endothelium, Vascular; Eplere | 2001 |
[Primary hyperaldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Algorithms; Amiloride; Di | 1998 |
Genetics of the mineralocorticoid system in primary hypertension.
Topics: Adrenal Glands; Aldosterone; Cytochrome P-450 CYP11B2; Humans; Hydrocortisone; Hydroxysteroid Dehydr | 2002 |
The neurohormonal natural history of essential hypertension: towards primary or tertiary aldosteronism?
Topics: Aldosterone; Cytochrome P-450 CYP11B2; Disease Progression; Humans; Hyperaldosteronism; Hypertension | 2002 |
Epithelial sodium channel and the control of sodium balance: interaction between genetic and environmental factors.
Topics: Aldosterone; Animals; Epithelial Sodium Channels; Extravascular Lung Water; Humans; Hypertension; So | 2002 |
Gene therapy for hypertension and restenosis.
Topics: Aldosterone; Animals; Coronary Restenosis; Genetic Therapy; Humans; Hypertension; Renin-Angiotensin | 2000 |
Is aldosterone the missing link in refractory hypertension?: aldosterone-to-renin ratio as a marker of inappropriate aldosterone activity.
Topics: Aldosterone; Antihypertensive Agents; Biomarkers; Humans; Hyperaldosteronism; Hypertension; Prevalen | 2002 |
Primary aldosteronism, a common entity? the myth persists.
Topics: Aldosterone; Biomarkers; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin | 2002 |
Familial varieties of primary aldosteronism.
Topics: Adrenocortical Adenoma; Aldosterone; Chromosome Mapping; Chromosomes, Human, Pair 7; Genetic Variati | 2001 |
Pathophysiology of propranolol in hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Diu | 1977 |
Acute and long-term studies of the mechanisms of action of beta-blocking drugs in lowering blood pressure.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Circadian Rhy | 1976 |
Clinical pharmacology of antihypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Bethanidine; Blo | 1977 |
[Incidence of beta-blockers on plasma renin activity. Present status].
Topics: Acebutolol; Adrenergic beta-Antagonists; Aldosterone; Blood Pressure; Depression, Chemical; Dose-Res | 1978 |
The renin system in essential, renovascular and adrenocortical hypertension: an overview.
Topics: Aldosterone; Blood Volume; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant | 1977 |
[Mineralocorticoid excess in essential hypertension].
Topics: 18-Hydroxydesoxycorticosterone; Aldosterone; Animals; Dehydroepiandrosterone; Humans; Hydroxycortico | 1979 |
Abnormal regulation of aldosterone in hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Circadian Rhythm; Diures | 1975 |
The renin-angiotensin-aldosterone system in parenchymal kidney disease.
Topics: Acute Kidney Injury; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Blood | 1975 |
Mineralocorticoid hormones.
Topics: Acid-Base Imbalance; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Anima | 1976 |
The adrenal cortex and essential hypertension.
Topics: Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Ani | 1976 |
Converting enzyme inhibition and blood pressure regulation.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Dogs | 1976 |
Drug-induced hypertension: pathogenesis and management.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Antidepressive Agents, Tricyclic; Carbenox | 1976 |
Experimental and clinical studies with converting enzyme inhibitor.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressur | 1976 |
The biochemistry of the renin-angiotensin system and its role in hypertension.
Topics: Aldosterone; Angiotensin II; Angiotensin III; Angiotensinogen; Animals; Cattle; Dogs; Endopeptidases | 1976 |
Kallikrein, kinins, and the kidney: what's going on in there?
Topics: Aldosterone; Humans; Hypertension; Kallikreins; Kidney; Kinins; Nephrons; Peptidyl-Dipeptidase A; Pr | 1978 |
Spirolactones: clinical and pharmacologic studies.
Topics: Aldosterone; Animals; Binding, Competitive; Canrenoic Acid; Canrenone; Diuresis; Humans; Hyperaldost | 1977 |
Mineralocorticoids in normal and hypertensive pregnancies.
Topics: Adrenocorticotropic Hormone; Aldosterone; Desoxycorticosterone; Female; Humans; Hypertension; Pregna | 1978 |
Control of aldosterone secretion.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Dogs; Humans; Hyperaldosteronism; | 1979 |
Interrelations between various blood pressure regulatory systems and the mosaic theory of hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Volume; Brain; Humans; Hypertension; Hyp | 1979 |
[Pathogenetic mechanisms of primary arterial hypertension in adolescents].
Topics: Adolescent; Age Factors; Aldosterone; Animals; Catecholamines; Cyclic AMP; Hemodynamics; Humans; Hyp | 1979 |
Renin-angiotensin system.
Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Amino Acid Sequence; Angiotens | 1975 |
Primary aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; | 1977 |
Experimental toxemia of pregnancy: review and speculation.
Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Dogs; Endocrine Glands; Female; Humans | 1977 |
Role of the adrenal cortex and sodium in the pathogenesis of human hypertension.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Animals; Dogs; Female; Humans; | 1978 |
[The effect of an angiotensin antagonist on blood pressure, renin and aldosterone secretion and its pathogenetic importance].
Topics: Aldosterone; Angiotensin II; Aortic Valve Stenosis; Bartter Syndrome; Binding, Competitive; Blood Pr | 1978 |
[Pathophysiological aspects of the renin-angiotensin-aldosterone system].
Topics: Adrenal Insufficiency; Aldosterone; Angiotensin II; Bartter Syndrome; Contraceptives, Oral; Half-Lif | 1977 |
Significance of renin and angiotensin in hypertension.
Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin I; Angiotensin II; Female; Humans; Hyper | 1978 |
[The renin-angiotensin-aldosterone system in diabetics].
Topics: Aldosterone; Angiotensin II; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic N | 1978 |
[Pathogenesis of arterial hypertension with a low renin activity in the blood plasma].
Topics: Adolescent; Adult; Age Factors; Aged; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteroni | 1978 |
[Primary aldosteronism--aldosterone-induced sodium storing hypertension--symptoms and differential diagnosis].
Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Alkalosis; Animals; Diagnosis, Differential; Dogs; F | 1979 |
Aging and the cardiovascular system.
Topics: Aged; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Cardiac Output; C | 1978 |
Pharmacologic interruption of the renin-angiotensin system.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Kidney; Renin; Structure | 1979 |
An apraisal of the role of aldosterone and the sympathetic nervous system in essential hypertension.
Topics: Aldosterone; Animals; Disease Models, Animal; Humans; Hyperaldosteronism; Hypertension; Sympathetic | 1979 |
Angiotensin as a renal, adrenal, and cardiovascular hormone: responses to saralasin in normal man and in essential and secondary hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressu | 1979 |
Low renin hypertension: a current review of definitions and controversies.
Topics: Aging; Aldosterone; Antihypertensive Agents; Black People; Electrolytes; Female; Humans; Hypertensio | 1979 |
[Prostaglandins, kallikrein-kinin and dopamine. Practical implications of this vasodilator-natriuretic system].
Topics: Aldosterone; Angiotensin II; Anti-Inflammatory Agents; Arachidonic Acids; Bartter Syndrome; Bradykin | 1979 |
[Renin-angiotensin-aldosterone system: the present status and problems].
Topics: Aldosterone; Angiotensin II; Animals; Enzyme Activation; Enzyme Precursors; Feedback; Humans; Hypera | 1979 |
[The adrenergic system in essential arterial hypertension].
Topics: Adrenal Glands; Aldosterone; Animals; Catecholamines; Central Nervous System; Humans; Hypertension; | 1979 |
Salt, volume and the prevention of hypertension.
Topics: Adult; Age Factors; Aldosterone; Animals; Culture; Diet, Sodium-Restricted; Diuretics; Extracellular | 1976 |
Interrelations of renin, angiotensin II, and sodium in hypertension and renal failure.
Topics: Acute Kidney Injury; Aldosterone; Angiotensin II; Animals; Blood Pressure; Glomerular Filtration Rat | 1976 |
Propranolol, renin and hypertension: a review.
Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Child; Clinical Trials as Topic; Female; Human | 1976 |
Cardiovascular and renal effects of head-out water immersion in man: application of the model in the assessment of volume homeostasis.
Topics: Aldosterone; Blood Volume; Diuresis; Extracellular Space; Hemodynamics; Hemostasis; Humans; Hydrosta | 1976 |
[Determination of aldosterone and other mineralocorticoids].
Topics: Adolescent; Adult; Age Factors; Aldosterone; Child; Child, Preschool; Circadian Rhythm; Diet; Humans | 1976 |
[Clinical aspects of hypertension under contraceptive steroids].
Topics: Adult; Aldosterone; Angiotensin II; Black or African American; Black People; Contraceptives, Oral; E | 1976 |
Angiotensin antagonists as diagnostic and pharmacologic tools.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Kidney; Kinetics; Propranolol; Re | 1976 |
The second Volhard Lecture: The use of blocking agents to define the functions of the renin--angiotensin system.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Calcium; Dogs; Hypertension; Hypertension, Ren | 1975 |
Vasopressor substances in normal and abnormal pregnancy.
Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Arginine Vasopressin; Catecholamines; Female; | 1975 |
Complications of systemic contraceptive agents: hypertension.
Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Drug Combination | 1975 |
Aldosterone and renin in essential hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adult; Age Factors; Aldosterone; Angiotensin II; Clinical Trials as | 1975 |
[Oral contraceptives and hypertension. A review].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Female; Hemodynamics; Humans; Hyp | 1975 |
Inter-relationships between plasma angiotensin II, arterial pressure, aldosterone and exchangeable sodium in normotensive and hypertensive man.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Hy | 1975 |
[Pathophysiology of hypertension].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Blood Pressure; Hemodynamics; Humans; Hypertension; Hyp | 1975 |
Aldosterone-specific membrane receptors and rapid non-genomic actions of mineralocorticoids.
Topics: Aldosterone; Animals; Biological Transport; Carrier Proteins; Cell Size; Desoxycorticosterone; Dogs; | 1992 |
Aldosterone regulation of gene transcription leading to control of ion transport.
Topics: Aldosterone; Biological Transport; Colon; Hypertension; Ion Channels; Kidney; Potassium; Receptors, | 1992 |
Cellular calcium and magnesium metabolism in the pathophysiology and treatment of hypertension and related metabolic disorders.
Topics: Aldosterone; Blood Glucose; Blood Pressure; Calcium; Calcium Channel Blockers; Cardiomegaly; Diabete | 1992 |
[The characteristics of the regulation of aldosterone secretion (a review of the literature)].
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Receptors, | 1991 |
What is the role of the central nervous system in mineralocorticoid hypertension?
Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Blood Vessels; Central Nervous System; Humans; | 1991 |
Vascular and cardiac actions of aldosterone and spironolactone.
Topics: Aldosterone; Animals; Electrocardiography; Humans; Hypertension; Muscle, Smooth, Vascular; Myocardia | 1991 |
Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system.
Topics: Aldosterone; Animals; Cardiomegaly; Fibrosis; Humans; Hypertension; Models, Cardiovascular; Myocardi | 1991 |
The renin-angiotensin system: renal actions and blood pressure regulation.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dogs; Humans; Hypertension; Kidney; Natriuresi | 1991 |
17 alpha-hydroxylation deficiency.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Child; Female; Humans; Hypertension | 1991 |
Dysregulation of aldosterone secretion and its relationship to the pathogenesis of essential hypertension.
Topics: Aldosterone; Angiotensin II; Homeostasis; Humans; Hypertension; Renin; Sodium, Dietary | 1991 |
Corticosteroids, kidneys, sweet roots and dirty drugs.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Aldosterone; Animals; Carbenoxolone; | 1991 |
Functional derangements in the regulation of aldosterone secretion in hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Kidney; Renin; Sodium; Sodium, Dietary | 1991 |
The causes of raised blood pressure in insulin-dependent and non-insulin-dependent diabetes.
Topics: Aldosterone; Blood Pressure; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopat | 1991 |
Non-modulating hypertension. A subset of sodium-sensitive hypertension.
Topics: Aldosterone; Homeostasis; Humans; Hypertension; Renal Circulation; Sodium | 1991 |
Post transplant hypertension.
Topics: Aldosterone; Cyclosporins; Humans; Hypertension; Kidney; Kidney Transplantation; Postoperative Care; | 1991 |
Dopaminergic regulation of aldosterone secretion. Biochemical mechanisms and pharmacology.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Biomechanical Phenomena; Cyclic AMP; Dihydroer | 1990 |
Diabetes mellitus, the renin-angiotensin system, and angiotensin-converting enzyme inhibition.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Diab | 1990 |
Primary hyperaldosteronism.
Topics: Aldosterone; Desoxycorticosterone; Electrolytes; Humans; Hyperaldosteronism; Hypertension; Kidney Tu | 1990 |
[The renin-angiotensin-aldosterone (RAA) system in endocrine diseases].
Topics: Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Cushing Syndrome; Endocrine System Diseases; H | 1990 |
A study of urinary and intracellular sodium and potassium, renin, aldosterone, and hypertension in blacks and Indians in Natal.
Topics: Aldosterone; Black or African American; Black People; Erythrocytes; Humans; Hypertension; India; Pot | 1990 |
Natriuretic effect of calcium antagonists.
Topics: Aldosterone; Animals; Calcium Channel Blockers; Glomerular Filtration Rate; Humans; Hypertension; Ki | 1985 |
Acute inhibition of the renin-angiotensin system: interest and limits to detect surgically curable hypertension.
Topics: Aldosterone; Blood Pressure; Captopril; Humans; Hypertension; Renin; Renin-Angiotensin System; Saral | 1985 |
Altered Ca-dependent fluxes of 42K in rat aorta during aldosterone-salt hypertension.
Topics: Aldosterone; Animals; Aorta; Calcium; Hypertension; Ion Channels; Rats; Sodium Chloride | 1986 |
Dopaminergic receptor mechanisms modulating the renin-angiotensin system and aldosterone secretion: an overview.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Depression, Chemical; Dopamine | 1989 |
Atrial natriuretic peptide. An important factor in sodium and blood pressure regulation.
Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Homeostasis; Humans; Hypertension; Natriures | 1989 |
Corcoran lecture: the case for or against salt in hypertension. Arthur Curtis Corcoran, MD (1909-1965). Tribute and prelude to Corcoran Lecture of 1988.
Topics: Aldosterone; Animals; Blood Pressure; Humans; Hypertension; Sodium; Sodium Chloride | 1989 |
The renin-angiotensin system. Normal physiology and changes in older hypertensives.
Topics: Aging; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Natriuresis; Renin-Angiote | 1989 |
Homeostatic regulation of potassium excretion.
Topics: Aldosterone; Animals; Central Nervous System; Cerebral Ventricles; Circadian Rhythm; Desoxycorticost | 1989 |
Sodium-sensitive hypertension. Implications of pathogenesis for therapy.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diet, Sodium- | 1989 |
Role of angiotensin and aldosterone in the pathogenesis of hypertension in insulin-dependent diabetes mellitus?
Topics: Aldosterone; Diabetes Mellitus, Type 1; Humans; Hypertension; Renin-Angiotensin System | 1989 |
Antihypertensive mechanisms of beta-adrenoceptor blockade: a review.
Topics: Adrenal Medulla; Adrenergic beta-Antagonists; Aldosterone; Animals; Antihypertensive Agents; Blood P | 1985 |
Biochemical indices associated with meditation practice: a literature review.
Topics: Aldosterone; Blood Circulation; Catecholamines; Cholesterol; Dopamine beta-Hydroxylase; Growth Hormo | 1985 |
Atrial natriuretic factor. A newly discovered hormone with significant clinical implications.
Topics: Adenylyl Cyclases; Adrenal Cortex; Aldosterone; Amino Acid Sequence; Animals; Antihypertensive Agent | 1986 |
Atrial natriuretic peptide: a new factor in hormonal control of blood pressure and electrolyte homeostasis.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Circulation; Blood Pressure; | 1986 |
Pharmacological influences on aldosterone secretion.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Dopamine; Histamine; Humans; Hypera | 1987 |
Atrial natriuretic hormone: a regulator of blood pressure and volume homeostasis.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Blood Volume; Hemodynamics; Homeost | 1988 |
[Diet therapy of obese and hypertensive patients. Efficacy and modality of the hypotensive action].
Topics: Aldosterone; Diet, Sodium-Restricted; Energy Intake; Humans; Hypertension; Obesity; Renin | 1987 |
The renin-angiotensin system and body function.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinoge | 1985 |
Syndrome of hypertension and hyperkalemia with normal glomerular filtration rate.
Topics: Adolescent; Adult; Aldosterone; Bicarbonates; Blood Pressure; Child; Diet, Sodium-Restricted; Diuret | 1986 |
Role of exogenous factors in alterations of red cell Na+-Li+ exchange and Na+-K+ cotransport in essential hypertension, primary hyperaldosteronism, and hypokalemia.
Topics: Adult; Aldosterone; Biological Transport, Active; Body Weight; Erythrocytes; Fatty Acids; Female; Ge | 1986 |
Potassium metabolism and hypertension.
Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aldosterone; Animals; Catecholamines; | 1985 |
[Angiotensin converting enzyme: its levels and its effect on blood pressure regulation].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Bradykinin; Humans; Hypertension; Peptidyl-Dipeptidase | 1986 |
Aldosterone, calcium, and hypertension.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel Blockers | 1986 |
Clinical applications of antimineralocorticoids.
Topics: Aldosterone; Angiotensin II; Ascites; Glucose; Heart Failure; Humans; Hypertension; Liver Cirrhosis; | 1988 |
[Vasoactive substances in normal pregnancy and in pregnancy complicated by gestosis].
Topics: Aldosterone; Female; Humans; Hypertension; Kallikreins; Pre-Eclampsia; Pregnancy; Pregnancy Complica | 1988 |
Hypertension: relating drug therapy to pathogenetic mechanisms.
Topics: Aldosterone; Angiotensinogen; Catecholamines; Creatinine; Humans; Hydrocortisone; Hyperaldosteronism | 1988 |
Low-renin hypertension of childhood.
Topics: Adolescent; Aldosterone; Child; Child, Preschool; Humans; Hypertension; Infant; Renin | 1987 |
Animal models of mineralocorticoid resistance.
Topics: Aldosterone; Animals; Corticosterone; Desoxycorticosterone; Dexamethasone; Disease Models, Animal; D | 1986 |
[Current status and prospects of the laboratory diagnosis of arterial hypertension].
Topics: Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Catecholamines; Diagnosis, Differential; Human | 1986 |
The renin-angiotensin system and long-term regulation of arterial pressure.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Fluids; Feedback; Hypertension; Kidney; N | 1986 |
Regulation of arterial pressure: role of pressure natriuresis and diuresis.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Diuresis; Homeostasis; Humans; Hypertension; K | 1986 |
Disorders of mineralocorticoid activity.
Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Specime | 1985 |
[Hypertensive syndrome in kidney diseases].
Topics: Aldosterone; Blood Pressure; Blood Volume; Diagnosis, Differential; Diuresis; Humans; Hyperaldostero | 1985 |
Calcium antagonists in the treatment of hypertension: a critical overview.
Topics: Aldosterone; Blood Pressure; Calcium; Calcium Channel Blockers; Cardiac Output; Catecholamines; Hear | 1985 |
The renal pressor system in human pregnancy.
Topics: Aldosterone; Alpha-Globulins; Angiotensin II; Contraceptives, Oral; Female; Humans; Hypertension; Ju | 1972 |
[Hemodynamic and hormonologic basis of the treatment of arterial hypertension].
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Cardiac Output; C | 1974 |
Inhibitors of adrenal steroid biosynthesis.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide | 1970 |
[Metabolism of corticoids].
Topics: Adipose Tissue; Adrenal Cortex Hormones; Aldosterone; Animals; Arthritis, Rheumatoid; Brain; Chemica | 1974 |
Assessment of adrenocortical function.
Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenal Glands; Adrenal Insufficiency; Adult; Aldoster | 1971 |
Aldosteronism and hypertension.
Topics: Aldosterone; Angiotensin II; Hyperaldosteronism; Hypertension; Renin | 1965 |
[Activity of renin-angiotensin in normal and abnormal conditions].
Topics: Adrenal Gland Diseases; Aldosterone; Angiotensin II; Humans; Hypertension; Kidney; Kidney Diseases; | 1967 |
Aldosterone in childhood.
Topics: Adolescent; Adrenal Glands; Adrenal Insufficiency; Adrenocortical Hyperfunction; Adrenocorticotropic | 1968 |
[The importance of angiotensin in clinical practice].
Topics: Aldosterone; Anaphylaxis; Angiotensin II; Animals; Blood Pressure; Glomerular Filtration Rate; Human | 1966 |
Pathophysiology of hypertension.
Topics: Aldosterone; Angiotensin II; Aorta; Carotid Sinus; Humans; Hypertension; Hypothalamus; Juxtaglomerul | 1967 |
Tissue hormones: angiotensin, bradykinin and the regulation of regional blood flows.
Topics: Aldosterone; Angiotensin II; Animals; Autonomic Nervous System; Bradykinin; Calcium; Catecholamines; | 1968 |
[Recent concept of primary aldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Insufficiency; Aldosterone; Angiotensin II; Carbohydrate M | 1967 |
[The renin-angiotensin-aldosterone system in late gestosis].
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Juxtaglomerular Apparatus; Pre-Eclampsia; | 1968 |
[Sodium in experimental hypertension].
Topics: Aldosterone; Angiotensin II; Animals; Desoxycorticosterone; Extracellular Space; Hypertension; Hyper | 1965 |
[Hypokalemic hypertension].
Topics: Acid-Base Equilibrium; Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Angiotensin II; Diureti | 1968 |
Recent developments in pathophysiologic studies of the renin-angiotensin system.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Amino Acid Sequence; Angiotensin II; Biological Assay | 1969 |
Neurogenic control of the blood pressure in hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Central Nervous System; Humans; Hypertension; Kidney; P | 1967 |
[Recent data on the physiopathologic metabolism of aldosterone].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Aorta; Edema; Female; Heart Disea | 1967 |
Control of aldosterone secretion by the renin-angiotensin system and by corticotropin.
Topics: Addison Disease; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Female; Humans; | 1968 |
[Renin--facts and hypotheses].
Topics: Acid-Base Equilibrium; Aldosterone; Amino Acids; Angiotensin II; Animals; Fibrinolysis; Humans; Hype | 1968 |
[Experimental bases of the pathophysiology of the renin-angiotensin system].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Female; Humans; Hyperaldosteronism; Hypertensi | 1968 |
[Renin-angiotensin-aldosterone system in blood pressure regulation disorders].
Topics: Adult; Aldosterone; Angiotensin II; Child; Electrolytes; Female; Humans; Hydrogen-Ion Concentration; | 1968 |
[Adrenal cortex function tests and their interpretation].
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Aldosterone; Androg | 1969 |
[Significance of renin in physiopathology and diagnosis].
Topics: Acute Kidney Injury; Aldosterone; Angiography; Angiotensin II; Humans; Hyperaldosteronism; Hypertens | 1969 |
[The role of renin in the pathophysiology and diagnosis, excluding pregnancy and its complications].
Topics: Aldosterone; Angiotensin II; Extracellular Space; Humans; Hyperaldosteronism; Hypertension; Kidney; | 1969 |
[Changes in renal hemodynamics and function in cardiac insufficiency].
Topics: Aldosterone; Angiotensin II; Animals; Arteriovenous Anastomosis; Cardiac Volume; Catecholamines; Diu | 1969 |
[New endocrine disorders attracting current interest--adrenal system].
Topics: Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Ho | 1969 |
[Hyperaldosteronism and the renin-angiotensin system].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Animals; Catecholamines | 1969 |
[Pathogenesis of arterial hypertension. Current trends and prospectives].
Topics: Aldosterone; Angiotensin II; Animals; Blood Vessels; Cardiac Output; Catecholamines; Humans; Hyperte | 1969 |
[The renin--angiotensin--aldosterone system].
Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Animals; Arteries; Blood Pressure; Blood Volum | 1969 |
[Renin-angiotensin-aldosterone system from the pathophysiological viewpoint].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Catecholamines; Cats; Chemical | 1969 |
[Endocrine function tests for etiological diagnosis of hypertensive patients].
Topics: Adult; Aldosterone; Angiotensin II; Catecholamines; Cushing Syndrome; Endocrine Glands; Glucocortico | 1970 |
[Role of the adrenal cortex in the pathogenesis of hypertension].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Hydrocortisone; Hyperaldosteronism; Hypertension; Renin | 1970 |
[Role of prostaglandins in the pathogenesis of arterial hypertension].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Kidney; Muscle, Smooth; Prostaglandins; Renin | 1970 |
[17-alpha-hydroxylase deficiency].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adul | 1971 |
[Hypertension caused by oral contraceptives].
Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Female; Humans; Hypertension; Renin | 1971 |
[Juxtaglomerular cell tumor and aldosterone-secreting renal tumor].
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Female; Hemangiope | 1971 |
Hypertension and chronic renal failure.
Topics: Aldosterone; Angiotensin II; Body Weight; Humans; Hypertension; Hypertension, Renal; Kidney Failure, | 1971 |
The relationship between angiotensin and aldosterone.
Topics: Adrenal Gland Neoplasms; Aldosterone; Alkalosis; Angiotensin II; Animals; Humans; Hyperaldosteronism | 1971 |
Perspectives in aldosterone and renin control.
Topics: Aldosterone; Angiotensin II; Animals; Bionics; Glomerular Filtration Rate; Humans; Hyperaldosteronis | 1971 |
[On mechanisms acting upon arterial blood pressure and sodium metabolism, particularly during pregnancy].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Feedback; Female; Humans; Hypertension; Kidney | 1971 |
[The renin-angiotensin-aldosterone system in arterial hypertension].
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Diagnosis, Differential; Feedback; Glomeru | 1971 |
[The renin-angiotensin-aldosterone system in arterial hypertension].
Topics: Adenoma; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Glomerular Filtration Rate; Homeo | 1971 |
[Arterial hypertension and oral contraceptives].
Topics: Adolescent; Adult; Age Factors; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure | 1971 |
Circulation: overall regulation.
Topics: Aldosterone; Angiotensin II; Blood Circulation; Blood Pressure; Body Fluids; Cardiac Output; Heart F | 1972 |
The adrenal cortex.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Ascorbic | 1972 |
Physiologic characteristics of hypertension.
Topics: Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Autonomic Nervous System; Blood Volume; Cardia | 1972 |
Renin, angiotensin and aldosterone system in pathogenesis and management of hypertensive vascular disease.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Angiotensin II; Contraceptives, Oral; | 1972 |
The cardiovascular effects of oral contraceptives.
Topics: Aldosterone; Angiotensin II; Blood Coagulation; Blood Flow Velocity; Blood Vessels; Cardiovascular S | 1972 |
Salt, water, and rest as a preventative for toxemia of pregnancy. A commentary and review.
Topics: Aldosterone; Angiotensin II; Blood Volume; Body Weight; Diabetes Insipidus; Diuresis; Diuretics; Ede | 1972 |
[Abnormalities of sodium and water metabolism with special reference to hypertensive diseases].
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hype | 1972 |
Endocrine causes of hypertension.
Topics: Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Angiotensin II; Catecholamines; | 1973 |
The role of renal factors in the pathogenesis of experimental hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Cadmium; Cattle; Chronic Disease; Embolism; Glomerulonephritis | 1973 |
The physiology of renin.
Topics: Aldosterone; Angiotensin II; Edema; Extracellular Space; Female; Glomerular Filtration Rate; Humans; | 1973 |
Significance of the effects of prostaglandins on renal and adrenal function in man.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Blood Pressure; Body Temperature; Cyclic AMP; | 1973 |
[Some new aspects of the renin-angiotensin system].
Topics: Aldosterone; Angiotensin II; Animals; Brain Chemistry; Dogs; Female; Humans; Hypertension; Mineraloc | 1973 |
[Renin-secreting tumors].
Topics: Aldosterone; Carcinoma, Small Cell; Diagnosis, Differential; Humans; Hypertension; Juxtaglomerular A | 1973 |
Aldosterone: review of its physiology and diagnostic aspects of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; | 1973 |
The pathophysiology of renin.
Topics: Aldosterone; Angiotensin II; Animals; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; | 1973 |
[Na metabolism anomaly in essential hypertension].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Natriuresis; Plasma Volume; Renin; Sodium | 1973 |
[Renin-angiotensin-aldosterone system in essential hypertension].
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Age | 1973 |
[Renin-angiotensin-(aldosterone)-system-clinical aspects].
Topics: Acute Kidney Injury; Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Aldosterone; Angioten | 1973 |
Perspectives on the renin-angiotensin-aldosterone system in hypertension.
Topics: Aldosterone; Angiotensin II; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; | 1974 |
The role of the renal medulla in hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Cardiac Output; Desoxycorticosterone; Extracellular Space; Hum | 1974 |
[Primary hypo- and hyperreninism].
Topics: Addison Disease; Adolescent; Adult; Aldosterone; Angiotensin II; Blood Volume; Diagnosis, Differenti | 1974 |
The renin-angiotensin system (first of two parts).
Topics: Aldosterone; Angiotensin II; Animals; Autonomic Nervous System; Biological Assay; Blood Pressure; Ch | 1974 |
[Primary aldosteronism].
Topics: Aldosterone; Angiotensin II; Desoxycorticosterone; Glucocorticoids; Humans; Hyperaldosteronism; Hype | 1973 |
Low-renin hypertension.
Topics: Adrenal Glands; Age Factors; Aldosterone; Angiotensin II; Blood Volume; Extracellular Space; Female; | 1974 |
[Oral contraceptives and arterial hypertension].
Topics: Aldosterone; Angiotensin II; Animals; Blood Circulation; Blood Pressure; Body Weight; Contraceptives | 1974 |
[Changes in the hemodynamics of patients with hypertension].
Topics: Aldosterone; Angiotensin II; Blood Flow Velocity; Blood Pressure; Cardiac Output; Heart; Hemodynamic | 1974 |
Sodium metabolism, aldosterone and the hypertensive disorders of pregnancy.
Topics: Aldosterone; Diuretics; Estrogens; Female; Humans; Hypertension; Posture; Pre-Eclampsia; Pregnancy; | 1972 |
Adrenal mineralocorticoids causing hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Corticosterone; Desoxyc | 1972 |
Instinct, appetites and medicine.
Topics: Aldosterone; Animals; Appetite; Biological Evolution; Disorders of Sex Development; Female; Humans; | 1972 |
[Diagnosis and therapy of primary hyperaldosteronism].
Topics: Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; H | 1972 |
Renin and hypertension: a review article.
Topics: Aldosterone; Humans; Hydrochlorothiazide; Hypertension; Juxtaglomerular Apparatus; Kidney Diseases; | 1973 |
Aldosteronism updated.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Dexamethasone; Diagnosis, Differentia | 1973 |
[Mineralocorticoids and essential hypertension].
Topics: Adrenal Glands; Aldosterone; Black or African American; Corticosterone; Desoxycorticosterone; Diet; | 1973 |
Improvements of metabolic and diagnostic assessment of human renal allotransplants.
Topics: Adrenal Glands; Aldosterone; Anemia; Biopsy, Needle; Cholinesterases; Erythropoietin; Fibrin; Graft | 1972 |
[Primary hypertension with low plasma renin level].
Topics: Aldosterone; Blood Pressure; Dexamethasone; Diagnosis, Differential; Female; Germany, West; Humans; | 1973 |
The use of spironolactone in the diagnosis and the treatment of hypertension associated with mineralocorticoid excess.
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Aldosterone; Antihypertensive Agents; Carc | 1973 |
[Disturbances in the endocrine functions of the kidneys].
Topics: Aldosterone; Erythropoiesis; Erythropoietin; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney | 1973 |
[Low renin essential hypertension].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin; Spironolactone; Trichlormet | 1973 |
[Clinical course, diagnosis and treatment of primary hyperaldosteronism].
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Cushing Syndrome; Diagnosis, Differential; Fe | 1974 |
[Heart diseases, hypertension and hormonal anomaly--with special reference to aldosterone and catecholamine].
Topics: Aldosterone; Catecholamines; Heart Diseases; Humans; Hypertension; Hyperthyroidism | 1967 |
Aldosterone, the adrenal cortex, and hypertension.
Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Animals; Bloo | 1968 |
[Abnormal secretion of aldosterone].
Topics: Adrenal Insufficiency; Adrenocortical Hyperfunction; Aldosterone; Animals; Dysautonomia, Familial; E | 1967 |
Shock following acute myocardial infarction. Current understanding of hemodynamic mechanisms.
Topics: Acidosis; Aldosterone; Animals; Arrhythmias, Cardiac; Arteries; Blood Flow Velocity; Blood Pressure; | 1968 |
Commentary on incidence of primary aldosteronism: current estimations based on objective data.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Blood Pressure; Desoxycorticosterone; | 1969 |
[Clinical problems in body fluid balance].
Topics: Acid-Base Equilibrium; Aldosterone; Body Fluids; Diabetes Insipidus; Edema; Glomerular Filtration Ra | 1969 |
[Aspect of hormones and hypertension].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Catechol | 1969 |
[Approach to the etiological study of essential hypertension].
Topics: Aldosterone; Animals; Catecholamines; Diagnosis, Differential; Hemodynamics; Humans; Hyperaldosteron | 1969 |
[Hypertension and aldosterone].
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension | 1970 |
[Relations between aldosterone secretion and hypertension].
Topics: Aldosterone; Animals; Humans; Hyperaldosteronism; Hypertension | 1970 |
[Recent knowledge of diseases with abnormal aldosterone secretion].
Topics: Addison Disease; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adult; Aldosterone; A | 1971 |
[Aldosterone (including in the urinary content)--how to read its figures].
Topics: Adrenal Glands; Age Factors; Aldosterone; Blood Chemical Analysis; Circadian Rhythm; Diet; Extracell | 1971 |
[Aldosterone deficiency].
Topics: Adult; Aldosterone; Autonomic Nervous System; Endocrine System Diseases; Heart Failure; Heparin; Hum | 1971 |
[Hypermineralocorticoidism and hypertension].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Cushing Syndrome; Dexam | 1971 |
[Mineralocorticoid function of the adrenal cortex under normal conditions and in pathology (review of the literature)].
Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenal Insufficiency; Adrenalectomy; Adult; Aging; Aldoster | 1971 |
[The third factor].
Topics: Aldosterone; Animals; Biological Assay; Dogs; Extracorporeal Circulation; Female; Glomerular Filtrat | 1971 |
[Aldosterone analysis (including urinary aldosterone test): interpretation of the test results].
Topics: Adrenal Glands; Adult; Age Factors; Aldosterone; Child; Circadian Rhythm; Diet; Humans; Hyperaldoste | 1969 |
Aldosterone and electrolyte balance in human hypertension.
Topics: Adrenocortical Hyperfunction; Aldosterone; Animals; Corticosterone; Furosemide; Humans; Hyperaldoste | 1970 |
Plasma renin concentration in human hypertension.
Topics: Aldosterone; Female; Heart Failure; Humans; Hypertension; Hypertension, Malignant; Kidney Failure, C | 1967 |
473 trials available for aldosterone and Hypertension
Article | Year |
---|---|
Enhanced Thrombotic Responses Are Associated With Striatin Deficiency and Aldosterone.
Topics: Aldosterone; Animals; Calmodulin-Binding Proteins; Fibrin; Hypertension; Membrane Proteins; Mice; Ne | 2021 |
The renoprotective effect of esaxerenone independent of blood pressure lowering: a post hoc mediation analysis of the ESAX-DN trial.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyperte | 2023 |
Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Cytochrome P-450 CYP11B2; Double-Blind Method; | 2023 |
Surgical versus medical treatment for unilateral primary aldosteronism: an alternative to a randomized controlled trial.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2023 |
CYP11B2 inhibitor dexfadrostat phosphate suppresses the aldosterone-to-renin ratio, an indicator of sodium retention, in healthy volunteers.
Topics: Adrenocorticotropic Hormone; Aldosterone; Cytochrome P-450 CYP11B2; Healthy Volunteers; Humans; Hype | 2023 |
Moderate dietary salt restriction improves blood pressure and mental well-being in patients with primary aldosteronism: The salt CONNtrol trial.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Sodi | 2023 |
Effect of angiotensin II receptor blocker and salt supplementation on short-term blood pressure variability in type 2 diabetes.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Cross-Over Studies; D | 2020 |
A combination of captopril challenge test after saline infusion test improves diagnostic accuracy for primary aldosteronism.
Topics: Adrenal Cortex Function Tests; Adult; Aldosterone; Captopril; Diagnosis, Differential; Drug Administ | 2020 |
Effects of Sodium Reduction on Energy, Metabolism, Weight, Thirst, and Urine Volume: Results From the DASH (Dietary Approaches to Stop Hypertension)-Sodium Trial.
Topics: Adult; Aldosterone; Basal Metabolism; Blood Pressure; Body Weight; Cross-Over Studies; Diet, Sodium- | 2020 |
Effects of dapagliflozin on renin-angiotensin-aldosterone system under renin-angiotensin system inhibitor administration.
Topics: Aged; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzh | 2020 |
Clinical outcomes of laparoscopic-based renal denervation plus adrenalectomy vs adrenalectomy alone for treating resistant hypertension caused by unilateral aldosterone-producing adenoma.
Topics: Adenoma; Adrenalectomy; Aldosterone; Blood Pressure; Denervation; Humans; Hypertension; Kidney; Lapa | 2020 |
Thirty-six-month results of laparoscopic-based renal denervation plus unilateral laparoscopic adrenalectomy for the treatment of patients with resistant hypertension caused by unilateral aldosterone-producing adenoma.
Topics: Adenoma; Adrenalectomy; Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; | 2021 |
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome | 2021 |
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome | 2021 |
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome | 2021 |
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome | 2021 |
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome | 2021 |
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome | 2021 |
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome | 2021 |
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome | 2021 |
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome | 2021 |
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi | 2021 |
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi | 2021 |
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi | 2021 |
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi | 2021 |
Effect of Reducing Sedentary Behavior on Blood Pressure (RESET BP): Rationale, design, and methods.
Topics: Accelerometry; Adult; Aged; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; COVI | 2021 |
Effects of Renin-Angiotensin-Aldosterone Inhibitors on Early Outcomes of Hypertensive COVID-19 Patients: A Randomized Triple-Blind Clinical Trial.
Topics: Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; | 2021 |
Plasma renin and aldosterone concentrations related to endovascular ultrasound renal denervation in the RADIANCE-HTN SOLO trial.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Denervation; Female; Humans; Hypertension; Kid | 2022 |
Integrative Blood Pressure Response to Upright Tilt Post Renal Denervation.
Topics: Aged; Aldosterone; Antihypertensive Agents; Arterial Pressure; Biomarkers; Cardiac Output; Cross-Sec | 2017 |
Physiological Phenotyping for Personalized Therapy of Uncontrolled Hypertension in Africa.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Black People; Blood Pressure; Drug Mo | 2017 |
Dietary Sodium Modifies Serum Uric Acid Concentrations in Humans.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Diet; Diet, Sodium-Restricted; Female; Humans; Hypertensio | 2017 |
The effect of treatment for sleep apnoea on determinants of blood pressure control.
Topics: Aged; Aldosterone; Blood Pressure; Catecholamines; Continuous Positive Airway Pressure; Cross-Over S | 2017 |
Aldosterone Is Not Associated With Metabolic and Microvascular Insulin Sensitivity in Abdominally Obese Men.
Topics: Adolescent; Adult; Aged; Aldosterone; Blood Glucose; Blood Pressure; Female; Humans; Hypertension; I | 2018 |
Adrenal Vein Sampling Is the Preferred Method to Select Patients With Primary Aldosteronism for Adrenalectomy: Con Side of the Argument.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Blood | 2018 |
Non-uniform relationship between salt status and aldosterone activity in patients with chronic kidney disease.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Cross-Over Studies; Diet, Sodium-Restricte | 2018 |
Greater reductions in plasma aldosterone with aliskiren in hypertensive patients with higher soluble (Pro)renin receptor level.
Topics: Aged; Aldosterone; Amides; Antihypertensive Agents; Blood Pressure; Female; Fumarates; Humans; Hyper | 2018 |
[The correlation between the carotid artery plaque and the change of aldosterone level related indexes during captopril challenge test].
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Carotid Stenosis; Humans; Hyperten | 2019 |
Time course of antiproteinuric effect of aliskiren in arterial hypertension associated with type 2 diabetes and microalbuminuria.
Topics: Adult; Aged; Albumins; Albuminuria; Aldosterone; Amides; Antihypertensive Agents; Arterial Pressure; | 2013 |
Evidence of primary aldosteronism in a predominantly female cohort of normotensive individuals: a very high odds ratio for progression into arterial hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Case-Control Studies; Cohort Studies; Dexamethasone; Diagn | 2013 |
Effect of acute and chronic vitamin D administration on systemic renin angiotensin system in essential hypertensives and controls.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calci | 2013 |
Procalcitonin and the inflammatory response to salt in essential hypertension: a randomized cross-over clinical trial.
Topics: Aldosterone; Biomarkers; Calcitonin; Calcitonin Gene-Related Peptide; Cross-Over Studies; Humans; Hy | 2013 |
Effect of aldosterone breakthrough on albuminuria during treatment with a direct renin inhibitor and combined effect with a mineralocorticoid receptor antagonist.
Topics: Aged; Albuminuria; Aldosterone; Amides; Blood Pressure; Dose-Response Relationship, Drug; Drug Thera | 2013 |
A randomised controlled trial evaluating the effect of potassium supplementation on vascular function and the renin-angiotensin-aldosterone system.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Cross-Over Studies; Double-Blind Method; Endothelium, Vasc | 2014 |
Long-term effects of irbesartan on plasma aldosterone concentration and left atrial volume in hypertensive patients.
Topics: Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Atrial Remodeling; Biphenyl | 2014 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre | 2013 |
Low dose spironolactone reduces blood pressure in patients with resistant hypertension and type 2 diabetes mellitus: a double blind randomized clinical trial.
Topics: Adult; Aged; Albumins; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitori | 2013 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Effects of aliskiren on blood pressure and humoral factors in hypertensive hemodialysis patients previously on angiotensin II receptor antagonists.
Topics: Adult; Aged; Aldosterone; Amides; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; | 2014 |
Marinobufagenin in essential hypertension and primary aldosteronism: a cardiotonic steroid with clinical and diagnostic implications.
Topics: Aldosterone; Blood Pressure; Bufanolides; Carotid Intima-Media Thickness; Essential Hypertension; Fe | 2015 |
A randomized controlled study of CPAP effect on plasma aldosterone concentration in patients with resistant hypertension and obstructive sleep apnea.
Topics: Aged; Aldosterone; Blood Pressure; Continuous Positive Airway Pressure; Drug Resistance; Female; Hum | 2014 |
Renin-angiotensin system phenotyping as a guidance toward personalized medicine for ACE inhibitors: can the response to ACE inhibition be predicted on the basis of plasma renin or ACE?
Topics: Aged; Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl | 2014 |
Greater efficacy of aldosterone blockade and diuretic reinforcement vs. dual renin-angiotensin blockade for left ventricular mass regression in patients with resistant hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Amiloride; Amlodipine; Angiotensin II Type 1 Receptor Blockers | 2014 |
Effects of spironolactone on dialysis patients with refractory hypertension: a randomized controlled study.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Dose-Res | 2014 |
Aldosterone, cognitive function, and cerebral hemodynamics in hypertension and antihypertensive therapy.
Topics: Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Cerebrovascular Circulation; Cognition; Fema | 2015 |
Effects of a contraceptive containing drospirenone and ethinylestradiol on blood pressure, metabolic profile and neurohumoral axis in hypertensive women at reproductive age.
Topics: Adult; Aldosterone; Androstenes; Antihypertensive Agents; Baroreflex; Blood Pressure; Body Mass Inde | 2014 |
Effects of the T/L-type calcium channel blocker benidipine on albuminuria and plasma aldosterone concentration. A pilot study involving switching from L-type calcium channel blockers to benidipine.
Topics: Aged; Albuminuria; Aldosterone; Blood Pressure; Calcium Channel Blockers; Creatinine; Dihydropyridin | 2014 |
Inappropriately elevated endothelin-1 plays a role in the pathogenesis of intradialytic hypertension.
Topics: Adrenomedullin; Adult; Aged; Aldosterone; Angiotensin II; Endothelin-1; Female; Humans; Hypertension | 2015 |
Impact of baroreflex activation therapy on renal function--a pilot study.
Topics: Aged; Aldosterone; Baroreflex; Blood Pressure; Female; Glomerular Filtration Rate; Humans; Hypertens | 2014 |
Angiotensin blockade in late autosomal dominant polycystic kidney disease.
Topics: Adolescent; Adult; Albuminuria; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Co | 2014 |
Respective effects of OSA treatment and angiotensin receptor blocker on aldosterone in hypertensive OSA patients: a randomized cross-over controlled trial.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Biomarkers; Cross-Over Studies; Female; Humans; Hyper | 2014 |
TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Case-Control Studies; Dioxygenase | 2015 |
Blood pressure-lowering effect of the sodium glucose co-transporter-2 inhibitor ertugliflozin, assessed via ambulatory blood pressure monitoring in patients with type 2 diabetes and hypertension.
Topics: Aldosterone; Antihypertensive Agents; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambu | 2015 |
Correlations of plasma renin activity and aldosterone concentration with ambulatory blood pressure responses to nebivolol and valsartan, alone and in combination, in hypertension.
Topics: Aldosterone; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Double-Blind M | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum | 2015 |
Effects of potassium supplementation on markers of osmoregulation and volume regulation: results of a fully controlled dietary intervention study.
Topics: Aged; Aldosterone; Biomarkers; Blood Pressure; Diet, Sodium-Restricted; Dietary Supplements; Double- | 2016 |
Low Response of Renin-Angiotensin System to Sodium Intake Intervention in Chinese Hypertensive Patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Biomarkers; Blood Pressure Determination; China; Diet, Sod | 2016 |
Changeover Trial of Azilsartan and Olmesartan Comparing Effects on the Renin-Angiotensin-Aldosterone System in Patients with Essential Hypertension after Cardiac Surgery (CHAOS Study).
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; | 2016 |
Effects of Vitamin D Supplementation on Plasma Aldosterone and Renin-A Randomized Placebo-Controlled Trial.
Topics: Aged; Aldosterone; Dietary Supplements; Double-Blind Method; Female; Humans; Hypertension; Male; Mid | 2016 |
Relationship Between Obesity, Hypertension, and Aldosterone Production in Postmenopausal African American Women: A Pilot Study.
Topics: Adipocytes; Aged; Aldosterone; Benzimidazoles; Black or African American; Cell Line; Culture Media, | 2016 |
Treatment with patiromer decreases aldosterone in patients with chronic kidney disease and hyperkalemia on renin-angiotensin system inhibitors.
Topics: Aged; Albuminuria; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzy | 2016 |
Neuroendocrine and Inflammatory Responses to Losartan and Continuous Positive Airway Pressure in Patients with Hypertension and Obstructive Sleep Apnea. A Randomized Controlled Trial.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Case-Control Studies; Continuous Positive Airw | 2016 |
Effects of continuous positive airway pressure treatment on aldosterone excretion in patients with obstructive sleep apnoea and resistant hypertension: a randomized controlled trial.
Topics: Aged; Aldosterone; Continuous Positive Airway Pressure; Coronary Vasospasm; Diuretics; Female; Follo | 2017 |
Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin.
Topics: Adult; Aged; Albuminuria; Aldosterone; Animals; Antihypertensive Agents; Diabetic Nephropathies; Fem | 2017 |
Development of hypertension and effects of benazepril hydrochloride in a canine remnant kidney model of chronic renal failure.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Benzazepines; Blood Pr | 2008 |
The ovarian cycle as a factor of variability in the laboratory screening for primary aldosteronism in women.
Topics: Adult; Aldosterone; Cohort Studies; False Positive Reactions; Female; Gonadal Steroid Hormones; Huma | 2009 |
Intravenous intralipid-induced blood pressure elevation and endothelial dysfunction in obese African-Americans with type 2 diabetes.
Topics: Adult; Aldosterone; Black or African American; Blood Pressure; C-Reactive Protein; Diabetes Mellitus | 2009 |
Differential effects of chlorthalidone versus spironolactone on muscle sympathetic nerve activity in hypertensive patients.
Topics: Aldosterone; Analysis of Variance; Blood Pressure; Chlorthalidone; Cross-Over Studies; Diuretics; He | 2009 |
A reverse postural test as a screening tool for aldosterone-producing adenoma: a pilot study.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Diagnosis, Differential; Exercise; Female; Hum | 2009 |
Low-Sodium DASH reduces oxidative stress and improves vascular function in salt-sensitive humans.
Topics: Adult; Aldosterone; Aorta; Blood Pressure; Cardiac Output; Diet, Sodium-Restricted; Elasticity; Elec | 2009 |
Long-term effect of efonidipine therapy on plasma aldosterone and left ventricular mass index in patients with essential hypertension.
Topics: Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzym | 2009 |
Aldosterone excess or escape: Treating resistant hypertension.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Bloo | 2009 |
Effects of ARB or ACE-inhibitor administration on plasma levels of aldosterone and adiponectin in hypertension.
Topics: Adiponectin; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin II Type 1 Receptor Blockers; A | 2009 |
Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Mass Index; Creatinine; Cross-Over Studies; Diet, Sod | 2009 |
Protective effects of efonidipine, a T- and L-type calcium channel blocker, on renal function and arterial stiffness in type 2 diabetic patients with hypertension and nephropathy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Aldosterone; Amlodipine; Arteries; Calcium Channel Blockers; Calc | 2009 |
Effects of angiotensin-converting enzyme inhibition on plasma aldosterone concentration, plasma renin activity, and blood pressure in spontaneously hypertensive cats with chronic renal disease.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Press | 2002 |
Safety and benefits of a tablet combining losartan and hydrochlorothiazide in Japanese diabetic patients with hypertension.
Topics: Adult; Albuminuria; Aldosterone; Antihypertensive Agents; Asian People; Blood Pressure; Cross-Over S | 2009 |
Time-dependent effects of low-dose aspirin on plasma renin activity, aldosterone, cortisol, and catecholamines.
Topics: Aged; Aldosterone; Aspirin; Catecholamines; Circadian Rhythm; Cross-Over Studies; Dose-Response Rela | 2009 |
Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Conve | 2010 |
Racial differences in potassium homeostasis in response to differences in dietary sodium in girls.
Topics: Adolescent; Aldosterone; Analysis of Variance; Black or African American; Blood Pressure; Body Weigh | 2010 |
Racial differences in potassium homeostasis in response to differences in dietary sodium in girls.
Topics: Adolescent; Aldosterone; Analysis of Variance; Black or African American; Blood Pressure; Body Weigh | 2010 |
Racial differences in potassium homeostasis in response to differences in dietary sodium in girls.
Topics: Adolescent; Aldosterone; Analysis of Variance; Black or African American; Blood Pressure; Body Weigh | 2010 |
Racial differences in potassium homeostasis in response to differences in dietary sodium in girls.
Topics: Adolescent; Aldosterone; Analysis of Variance; Black or African American; Blood Pressure; Body Weigh | 2010 |
Does the ratio of serum aldosterone to plasma renin activity predict the efficacy of diuretics in hypertension? Results of RENALDO.
Topics: Aldosterone; Bendroflumethiazide; Blood Pressure; Cross-Over Studies; Diuretics; Drug Therapy, Combi | 2010 |
Effect of body weight loss and normalization on blood pressure in overweight non-obese patients with stage 1 hypertension.
Topics: Aged; Aldosterone; Blood Glucose; Blood Pressure; Body Mass Index; Diet, Reducing; Female; Humans; H | 2010 |
Diagnosis of primary aldosteronism: comparison of post-captopril active renin concentration and plasma renin activity.
Topics: Adult; Aged; Aldosterone; Area Under Curve; Captopril; Diagnosis, Differential; Female; Humans; Hype | 2010 |
Impact of different diagnostic criteria during adrenal vein sampling on reproducibility of subtype diagnosis in patients with primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Aldosterone; Cath | 2010 |
Impact of different diagnostic criteria during adrenal vein sampling on reproducibility of subtype diagnosis in patients with primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Aldosterone; Cath | 2010 |
Impact of different diagnostic criteria during adrenal vein sampling on reproducibility of subtype diagnosis in patients with primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Aldosterone; Cath | 2010 |
Impact of different diagnostic criteria during adrenal vein sampling on reproducibility of subtype diagnosis in patients with primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Aldosterone; Cath | 2010 |
Effects of eprosartan on diastolic function and neurohormones in patients with hypertension and diastolic dysfunction.
Topics: Acrylates; Aged; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Bloo | 2010 |
[Does spironolactone use at arterial hypertension therapy protect endothelium also in smoking patients?].
Topics: Aldosterone; Diuretics; Endothelin-1; Endothelium, Vascular; Female; Humans; Hypertension; Male; Mid | 2009 |
Impact of aldosterone receptor blockade compared with thiazide therapy on sympathetic nervous system function in geriatric hypertension.
Topics: Aged; Aldosterone; Blood Pressure; Body Composition; Catecholamines; Diuretics; Female; Heart Rate; | 2010 |
Beta2-adrenergic receptor genotype affects the renin-angiotensin-aldosterone system response to the Dietary Approaches to Stop Hypertension (DASH) dietary pattern.
Topics: Aldosterone; Alleles; Blood Pressure; Diet; Female; Genotype; Humans; Hypertension; Male; Middle Age | 2010 |
Effect of modest salt reduction on skin capillary rarefaction in white, black, and Asian individuals with mild hypertension.
Topics: Adult; Aged; Aldosterone; Asian People; Black People; Capillaries; Diet, Sodium-Restricted; Double-B | 2010 |
A new-generation N/L-type calcium channel blocker leads to less activation of the renin-angiotensin system compared with conventional L type calcium channel blocker.
Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin I; Angiotensin II; Blood Pressure; Calcium C | 2010 |
Effects of ACE inhibitors on cardiac angiotensin II and aldosterone in humans: "Relevance of lipophilicity and affinity for ACE".
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Aorta, Thoracic; | 2010 |
Simvastatin reduces sympathetic activity in men with hypertension and hypercholesterolemia.
Topics: Adult; Aldosterone; Anticholesteremic Agents; Blood Pressure; Catecholamines; Comorbidity; Double-Bl | 2010 |
Role of plasma aldosterone concentration in regression of left-ventricular mass following antihypertensive medication.
Topics: Adult; Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agen | 2011 |
Benidipine reduces albuminuria and plasma aldosterone in mild-to-moderate stage chronic kidney disease with albuminuria.
Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calciu | 2011 |
Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin.
Topics: Adult; Aldosterone; Androstanols; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Protei | 2011 |
Additive antioxidative effects of azelnidipine on angiotensin receptor blocker olmesartan treatment for type 2 diabetic patients with albuminuria.
Topics: Aged; Albuminuria; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; B | 2011 |
Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertension.
Topics: Aldosterone; Amides; Antihypertensive Agents; Blood Pressure; Demography; Female; Fumarates; Heart V | 2011 |
Tagging SNPs in REN, AGTR1 and AGTR2 genes and response of renin activity, angiotensin II and aldosterone concentrations to antihypertensive treatment in Kazakans.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aten | 2011 |
Effects of olmesartan on the renin-angiotensin-aldosterone system for patients with essential hypertension after cardiac surgery--investigation using a candesartan change-over study.
Topics: Aged; Aldosterone; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; An | 2011 |
Olmesartan medoxomil treatment is associated with decreased plasma B-type natriuretic peptide levels in patients on hemodialysis.
Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Female; Humans; Hyper | 2012 |
Effects of a novel aldosterone synthase inhibitor for treatment of primary hypertension: results of a randomized, double-blind, placebo- and active-controlled phase 2 trial.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Cytochrome | 2011 |
Abnormal increase in urinary aquaporin-2 excretion in response to hypertonic saline in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Aquaporin 2; Atrial Natriuretic Factor; Cross-Over Studies; Cycl | 2012 |
Efficacy analysis of the renoprotective effects of aliskiren in hypertensive patients with chronic kidney disease.
Topics: Aged; Albuminuria; Aldosterone; Amides; Antihypertensive Agents; Biomarkers; Blood Pressure; Diabeti | 2013 |
Association between postexercise hypotension and long-term training-induced blood pressure reduction: a pilot study.
Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Decision Support Techniques; Exercise Test; Exercise | 2013 |
Adrenalectomy reverses myocardial fibrosis in patients with primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Cardiomyopathies; Echocardiography; Fe | 2012 |
Hypertensive left ventricular hypertrophy: a mechanistic approach to optimizing regression assessed by cardiovascular magnetic resonance.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Female; Humans; Hypertension; Hypertrophy, Left V | 2012 |
L/N-type calcium channel blocker cilnidipine reduces plasma aldosterone, albuminuria, and urinary liver-type fatty acid binding protein in patients with chronic kidney disease.
Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensiv | 2013 |
The effects of aldosterone synthase inhibition on aldosterone and cortisol in patients with hypertension: a phase II, randomized, double-blind, placebo-controlled, multicenter study.
Topics: Adolescent; Adult; Aged; Aldosterone; Arterial Pressure; Cytochrome P-450 CYP11B2; Double-Blind Meth | 2012 |
Effect of amiloride and spironolactone on renal tubular function and central blood pressure in patients with arterial hypertension during baseline conditions and after furosemide: a double-blinded, randomized, placebo-controlled crossover trial.
Topics: Aged; Aldosterone; Amiloride; Angiotensin II; Aquaporin 2; Blood Pressure; Cross-Over Studies; Diure | 2013 |
Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter.
Topics: Adult; Aldosterone; Blood Pressure; Body Mass Index; Diet; Dose-Response Relationship, Drug; Female; | 2012 |
Angiotensin II, independent of plasma renin activity, contributes to the hypertension of autonomic failure.
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; | 2013 |
Vasoactive modulators during and after craniotomy: relation to postoperative hypertension.
Topics: Adult; Aged; Aldosterone; Anesthesia; Atrial Natriuretic Factor; Blood Pressure; Catecholamines; Cra | 2002 |
Vasoactive modulators during and after craniotomy: relation to postoperative hypertension.
Topics: Adult; Aged; Aldosterone; Anesthesia; Atrial Natriuretic Factor; Blood Pressure; Catecholamines; Cra | 2002 |
Vasoactive modulators during and after craniotomy: relation to postoperative hypertension.
Topics: Adult; Aged; Aldosterone; Anesthesia; Atrial Natriuretic Factor; Blood Pressure; Catecholamines; Cra | 2002 |
Vasoactive modulators during and after craniotomy: relation to postoperative hypertension.
Topics: Adult; Aged; Aldosterone; Anesthesia; Atrial Natriuretic Factor; Blood Pressure; Catecholamines; Cra | 2002 |
Additive effect of drospirenone/17-beta-estradiol in hypertensive postmenopausal women receiving enalapril.
Topics: Aldosterone; Androstenes; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Double-Bli | 2002 |
Influence of AT1 receptor blockade on blood pressure, renal haemodynamics and hormonal responses to intravenous angiotensin II infusion in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl | 2002 |
Effect of spironolactone on impaired fibrinolysis of hypertensive patients.
Topics: Adult; Aged; Aldosterone; Female; Fibrinolysis; Humans; Hypertension; Male; Middle Aged; Mineralocor | 2002 |
Hyperaldosteronism among black and white subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug | 2002 |
Hyperaldosteronism among black and white subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug | 2002 |
Hyperaldosteronism among black and white subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug | 2002 |
Hyperaldosteronism among black and white subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug | 2002 |
Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism.
Topics: Aldosterone; Amlodipine; Antihypertensive Agents; Atenolol; Biphenyl Compounds; Confounding Factors, | 2002 |
Racial difference in the activity of the amiloride-sensitive epithelial sodium channel.
Topics: Adolescent; Adult; Aldosterone; Amiloride; Black People; Blood Pressure; Body Mass Index; Cohort Stu | 2002 |
Efficacy and tolerability of eplerenone and losartan in hypertensive black and white patients.
Topics: Adult; Aldosterone; Analysis of Variance; Angiotensin Receptor Antagonists; Antihypertensive Agents; | 2003 |
Plasma fatty acids response to central volume expansion in salt-sensitive hypertension.
Topics: Adult; Aldosterone; Blood Volume; Creatinine; Fatty Acids, Nonesterified; Female; Humans; Hypertensi | 2003 |
Effect of amlodipine, quinapril, and losartan on pulse wave velocity and plasma collagen markers in patients with mild-to-moderate arterial hypertension.
Topics: Adult; Aldosterone; Amlodipine; Antihypertensive Agents; Biomarkers; Blood Flow Velocity; Blood Pres | 2003 |
Assessment of the novel selective aldosterone blocker eplerenone using ambulatory and clinical blood pressure in patients with systemic hypertension.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Eplerenone; Female; Heart | 2003 |
One year follow-up of hormone replacement therapy with percutaneous estradiol and low-dose vaginal natural progesterone in women with mild to moderate hypertension.
Topics: Administration, Cutaneous; Administration, Intravaginal; Aldosterone; Amlodipine; Antihypertensive A | 2003 |
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens | 2003 |
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens | 2003 |
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens | 2003 |
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens | 2003 |
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens | 2003 |
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens | 2003 |
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens | 2003 |
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens | 2003 |
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens | 2003 |
Synthetic human alpha-atrial natriuretic peptide improves the management of postoperative hypertension and renal dysfunction after the repair of abdominal aortic aneurysm.
Topics: Aged; Aldosterone; Aortic Aneurysm, Abdominal; Atrial Natriuretic Factor; Chi-Square Distribution; F | 2003 |
Acute angiotensin II increases plasma F2-isoprostanes in salt-replete human hypertensives.
Topics: Adult; Aldosterone; Angiotensin II; Biomarkers; Blood Pressure; Drug Interactions; F2-Isoprostanes; | 2003 |
Effect of an angiotensin II type 1 receptor blocker, valsartan, on neurohumoral factors in patients with hypertension: comparison with a long-acting calcium channel antagonist, amlodipine.
Topics: Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Co | 2003 |
Hemodynamic effects of amlodipine, bisoprolol, and lisinopril in hypertensive patients after liver transplantation.
Topics: Adult; Aged; Aldosterone; Amlodipine; Antihypertensive Agents; Bisoprolol; Cross-Over Studies; Femal | 2004 |
Randomized double-blind placebo-controlled study of an angiotensin immunotherapeutic vaccine (PMD3117) in hypertensive subjects.
Topics: Adolescent; Adult; Aged; Aldosterone; Aluminum Hydroxide; Angiotensin I; Angiotensin-Converting Enzy | 2004 |
Active renin versus plasma renin activity to define aldosterone-to-renin ratio for primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Differential Threshold; Female; Humans; | 2004 |
Genetic factors associated with volume-sensitive hypertension.
Topics: Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Blood Volume; Calmodulin-Binding Proteins | 2004 |
Influence of dietary sodium on the renin-angiotensin-aldosterone system and prevalence of left ventricular hypertrophy by EKG criteria.
Topics: Aldosterone; Blood Pressure; Electrocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ve | 2005 |
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2005 |
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2005 |
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2005 |
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2005 |
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2005 |
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2005 |
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2005 |
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2005 |
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2005 |
Aldosterone-to-renin ratio, arterial stiffness, and the response to aldosterone antagonism in essential hypertension.
Topics: Aldosterone; Arteries; Bendroflumethiazide; Blood Flow Velocity; Blood Pressure; Compliance; Cross-O | 2005 |
Effects of circadian rhythms, posture, and medication on renin-aldosterone interrelations in essential hypertensives.
Topics: Adult; Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Convertin | 2005 |
Mechanisms of hypertension after liver transplantation.
Topics: Adult; Aged; Aldosterone; Endothelin-1; Female; Humans; Hypertension; Liver Transplantation; Male; M | 2005 |
Effect of spironolactone on blood pressure and the renin-angiotensin-aldosterone system in oligo-anuric hemodialysis patients.
Topics: Adult; Aldosterone; Antihypertensive Agents; Anuria; Blood Pressure; Body Weight; Cross-Over Studies | 2005 |
Endogenous ouabain and acute salt loading in low-renin hypertension.
Topics: Adrenocorticotropic Hormone; Aldosterone; Biomarkers; Blood Pressure; Cardenolides; Female; Hormones | 2005 |
Effects of dual blockade of the renin angiotensin system in hypertensive type 2 diabetic patients with nephropathy.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Conve | 2005 |
Central role for ENaC in development of hypertension.
Topics: Aldosterone; Amiloride; Antihypertensive Agents; Blood Pressure; Epithelial Sodium Channels; Humans; | 2005 |
Effects of a new hormone therapy, drospirenone and 17-beta-estradiol, in postmenopausal women with hypertension.
Topics: Aged; Aldosterone; Androstenes; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cholesterol; | 2006 |
Dual blockade of angiotensin II with enalapril and losartan reduces proteinuria in hypertensive patients with type 2 diabetes.
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents | 2006 |
Effects of spironolactone during an angiotensin II receptor blocker treatment on the left ventricular mass reduction in hypertensive patients with concentric left ventricular hypertrophy.
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl | 2006 |
Can the blood pressure effects of COX-2 selective inhibitors be explained by changes in plasma aldosterone levels?
Topics: Aged; Aldosterone; Blood Pressure; Celecoxib; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Femal | 2006 |
Bovine casein hydrolysate (c12 Peptide) reduces blood pressure in prehypertensive subjects.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Case | 2007 |
Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study.
Topics: Aldosterone; Bendroflumethiazide; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Ren | 2007 |
Prospective evaluation of the saline infusion test for excluding primary aldosteronism due to aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hydrocortisone; Hype | 2007 |
Prospective evaluation of the saline infusion test for excluding primary aldosteronism due to aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hydrocortisone; Hype | 2007 |
Prospective evaluation of the saline infusion test for excluding primary aldosteronism due to aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hydrocortisone; Hype | 2007 |
Prospective evaluation of the saline infusion test for excluding primary aldosteronism due to aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hydrocortisone; Hype | 2007 |
The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio.
Topics: Aged; Aldosterone; Amiloride; Bendroflumethiazide; Cross-Over Studies; Double-Blind Method; Female; | 2007 |
Gradual reactivation of vascular angiotensin I to angiotensin II conversion during chronic ACE inhibitor therapy in patients with diabetes mellitus.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; B | 2007 |
Pharmacokinetics and pharmacodynamics of drospirenone-estradiol combination hormone therapy product coadministered with hydrochlorothiazide in hypertensive postmenopausal women.
Topics: Aged; Aldosterone; Androstenes; Antihypertensive Agents; Area Under Curve; Biological Availability; | 2007 |
Comparison of the effects of efonidipine and amlodipine on aldosterone in patients with hypertension.
Topics: Aged; Aged, 80 and over; Aldosterone; Amlodipine; Blood Pressure; Calcium Channel Blockers; Calcium | 2007 |
Aldosterone escape with diuretic or angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker combination therapy in patients with mild to moderate hypertension.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biph | 2007 |
Aldosterone breakthrough during angiotensin II receptor blockade in hypertensive patients with diabetes mellitus.
Topics: Aged; Albuminuria; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Co | 2007 |
Spironolactone for poorly controlled hypertension in type 2 diabetes: conflicting effects on blood pressure, endothelial function, glycaemic control and hormonal profiles.
Topics: Aged; Aldosterone; Angiotensin II; Blood Glucose; Blood Pressure; Body Mass Index; Cross-Over Studie | 2008 |
Enalapril and atenolol in primary hypertension--a comparative study of blood pressure lowering and hormonal effects.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolo | 1984 |
Effect of dietary sodium on angiotensin-converting enzyme (ACE) inhibition and the acute hypotensive effect of enalapril (MK-421) in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; B | 1984 |
Long-term clinical experience with enalapril in essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Therapy, Combina | 1983 |
Blood pressure and hormonal changes following alteration in dietary sodium and potassium in mild essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Diet, Sodium-Restricted; Double-Blind | 1981 |
Blood pressure and hormonal changes following alteration in dietary sodium and potassium in young men with and without a familial predisposition to hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Diet; Hormones; Humans; Hypertension; | 1981 |
Lack of beta-adrenoreceptor hypersensitivity after abrupt withdrawal of long-term therapy with oxprenolol.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Delayed-Action Preparations; Drug Hypersensitivity; | 1981 |
Acute effects of prizidilol on blood pressure, heart rate, catecholamines, renin and aldosterone in essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Female; Heart | 1982 |
Antihypertensive effects of bunitrolol in essential hypertension.
Topics: Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Mid | 1983 |
Single-agent and combination therapy of essential hypertension.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Diuretics; Drug Therapy | 1984 |
Bucindolol, a beta-adrenoceptor blocker with vasodilatory action: its effect in systemic hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Drug Therapy, Combination; Female; | 1984 |
Antihypertensive and humoral effects of verapamil and nifedipine in essential hypertension.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Volume; Calcium Channel Blockers; | 1982 |
The relation between cardiac hypertrophy and hypertension.
Topics: Aldosterone; Blood Glucose; Blood Pressure; Cardiomegaly; Heart Ventricles; Humans; Hypertension; In | 1983 |
[A new principle in long-term treatment of essential hypertension: angiotensin-converting enzyme inhibition (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captop | 1980 |
Uncontrollable hypertension in patients on hemodialysis: long-term treatment with captopril and salt subtraction.
Topics: Adolescent; Adult; Aldosterone; Captopril; Child; Clinical Trials as Topic; Female; Humans; Hyperten | 1981 |
Fluctuations in the plasma angiotensin I converting enzyme activity during long-term treatment with captopril.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; M | 1982 |
Low-dose captopril: its use in mild to moderate hypertension unresponsive to diuretic treatment.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Clini | 1982 |
A comparative pilot study of enalapril, a new converting enzyme inhibitor, and hydrochlorothiazide in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Dipeptides; Enal | 1982 |
The effect of captopril and propranolol on the responses to posture and isometric exercise in patients with essential hypertension.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Fe | 1983 |
[Clinical study of the efficacy of oral potassium canrenoate and spironolactone in essential arterial hypertension].
Topics: Administration, Oral; Adult; Aldosterone; Blood Pressure; Canrenoic Acid; Clinical Trials as Topic; | 1983 |
Captopril, aldosterone and urinary kallikrein in primary hypertension.
Topics: Aldosterone; Angiotensin II; Captopril; Humans; Hydrochlorothiazide; Hypertension; Kallikreins; Prol | 1983 |
Clinical efficacy, safety, and pharmacokinetics of indapamide in renal impairment.
Topics: Aldosterone; Blood Pressure; Body Weight; Diuretics; Hemodynamics; Humans; Hypertension; Indapamide; | 1983 |
The effects of piretanide on catecholamine metabolism, plasma renin activity and serum aldosterone: a double-blind pilot comparison against hydrochlorothiazide in patients with essential hypertension.
Topics: Aged; Aldosterone; Blood Pressure; Catecholamines; Diuretics; Dopamine; Double-Blind Method; Female; | 1984 |
Effects of indomethacin, sulindac, naproxen, aspirin, and paracetamol in treated hypertensive patients.
Topics: Acetaminophen; Aldosterone; Aspirin; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; | 1984 |
Efficacy of low-dose captopril given twice daily to patients with essential hypertension uncontrolled by a beta blocker plus thiazide diuretic.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Captopril; Chlorthalidone; Dose-Response Relationship, Dru | 1984 |
Clinical biochemical and haemodynamic correlates of sodium sensitivity in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Diet, Sodium-Restricted; Female; Forea | 1983 |
Sodium sensitivity in essential hypertension: role of the renin-angiotensin-aldosterone system and predictive value of an intravenous frusemide test.
Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Diet; Female; Furosemide; Humans; Hypertension; Mal | 1984 |
[Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension].
Topics: Adult; Aged; Aldosterone; Calcium Channel Blockers; Electrolytes; Female; Heart Rate; Humans; Hydroc | 1984 |
Antihypertensive and metabolic effects of increasing doses of atenolol and labetalol. A comparative study in primary hypertension.
Topics: Adult; Aged; Aldosterone; Atenolol; Blood Pressure; Double-Blind Method; Drug Evaluation; Ethanolami | 1982 |
[Controlled study of the anti-hypertensive effects of indapamide, metoprolol and their combination in patients with essential arterial hypertension].
Topics: Adult; Aged; Aldosterone; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Exercise T | 1982 |
[Controlled study of antihypertensive effects of indapamide and metoprolol and their combination in patients with essential arterial hypertension].
Topics: Adult; Aged; Aldosterone; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; He | 1982 |
Controlled trial of biofeedback-aided behavioural methods in reducing mild hypertension.
Topics: Adult; Aldosterone; Biofeedback, Psychology; Cholesterol; Clinical Trials as Topic; Female; Humans; | 1981 |
Captopril in essential hypertension; contrasting effects of adding hydrochlorothiazide or propranolol.
Topics: Adult; Aged; Aldosterone; Body Weight; Captopril; Clinical Trials as Topic; Drug Therapy, Combinatio | 1982 |
Reduced pressor effect of angiotensin II and of noradrenaline in normal man following the oral administration of the calcium-antagonist nifedipine.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; | 1982 |
Response of thiazide-induced hypokalemia to amiloride.
Topics: Aldosterone; Amiloride; Bicarbonates; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypert | 1983 |
Spironolactone and triamterene in volume-dependent essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Hum | 1980 |
Hemodynamic changes during long-term thiazide treatment of essential hypertension in responders and nonresponders.
Topics: Adult; Aldosterone; Blood Volume; Body Weight; Diuresis; Hemodynamics; Humans; Hydrochlorothiazide; | 1980 |
Antihypertensive effect of fractionated sublingual administration of nifedipine in moderate essential hypertension.
Topics: Administration, Oral; Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Clinical Trials a | 1980 |
Effect of moderate salt restriction and high potassium intake on pressor hormones, response to noradrenaline and baroreceptor function in man.
Topics: Adult; Aldosterone; Blood Pressure; Diet; Diet, Sodium-Restricted; Heart Rate; Humans; Hypertension; | 1980 |
Captopril, an orally active converting enzyme inhibitor, in the treatment of primary hypertension. A controlled long-term study with reference to initial plasma renin activity.
Topics: Adult; Aldosterone; Captopril; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combinat | 1981 |
The renin-aldosterone system during exercise in young patients with essential hypertension.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Male; Physical Exertion; Renin; Sodium Chloride | 1981 |
Antihypertensive and hormonal effects of single oral doses of captopril and nifedipine in essential hypertension.
Topics: Administration, Oral; Adult; Aged; Aldosterone; Captopril; Female; Humans; Hypertension; Male; Middl | 1981 |
Correlation between propranolol in plasma and urine, renin-aldosterone system and blood pressure in essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Ma | 1981 |
[Effect of propranolol on diuretic activity of furosemide hypertensive patients (author's transl)].
Topics: Aldosterone; Diuresis; Drug Synergism; Female; Furosemide; Humans; Hypertension; Male; Osmolar Conce | 1981 |
Merits of adding a beta blocker (acebutolol) to a diuretic (hydrochlorothiazide) in the treatment of hypertension.
Topics: Acebutolol; Adult; Aldosterone; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combina | 1982 |
Effects of once daily indapamide and pindolol on blood pressure, plasma aldosterone concentration and plasma renin activity in a general practice setting.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Diuretics; Family Practice; Heart Rate; Humans; Hypertensi | 1982 |
Interaction between oxprenolol and indomethacin on blood pressure in essential hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Interactions | 1982 |
[Spironolactone in essential hypertension associated with abnormal aldosterone regulation and in Conn's syndrome (author's transl)].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi | 1980 |
Young borderline hypertensives are hyperreactive to mental arithmetic stress: spectral analysis of R-R intervals.
Topics: Adult; Aging; Aldosterone; Blood Pressure; Electrocardiography; Heart Rate; Humans; Hypertension; Ma | 1995 |
Renin-angiotensin-aldosterone system, RR interval, and blood pressure variability during postural changes in borderline arterial hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; | 1995 |
Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM.
Topics: Albuminuria; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Blood P | 1995 |
Age is a major determinant of the divergent blood pressure responses to varying salt intake in essential hypertension.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; | 1995 |
Effects of losartan on the renin-angiotensin-aldosterone axis in essential hypertension.
Topics: Aldosterone; Angiotensin II; Biphenyl Compounds; Blood Pressure; Creatinine; Drug Combinations; Fema | 1995 |
Differing mechanisms of action of angiotensin-converting enzyme inhibition in black and white hypertensive patients. The Trandolapril Multicenter Study Group.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Blood | 1995 |
Divergent effects of dihydropyridine and phenylalkylamine calcium channel antagonist classes on autonomic function in human hypertension.
Topics: Aldosterone; Analysis of Variance; Autonomic Nervous System; Baroreflex; Calcium Channel Blockers; C | 1995 |
Normal sympathetic vasomotor and cardiac parasympathetic activities in patients with primary aldosteronism: assessment by spectral analysis.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Blood Pressure; Electroca | 1995 |
Hormonal and renal responses to atrial natriuretic peptide infusion in low-renin hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Cross-Over Studies; Double-Blind Method; Glomerular F | 1995 |
Comparison of moexipril, a new ACE inhibitor, to verapamil-SR as add-on therapy to low dose hydrochlorothiazide in hypertensive patients.
Topics: Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Delayed-Action Preparat | 1995 |
Regulation of sodium excretion in human hypertension: long-term effects of calcium antagonist and angiotensin converting enzyme inhibitor.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Calcium Cha | 1993 |
Hemodynamic and humoral effects of the angiotensin II antagonist losartan in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bod | 1994 |
Salt sensitive essential hypertension evaluated by 24 hour ambulatory blood pressure.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Blood Pressure Monitoring, Ambulatory | 1994 |
[Potassium citrate versus potassium chloride in essential hypertension. Effects on hemodynamic, hormonal and metabolic parameters].
Topics: Adult; Aged; Aldosterone; Blood Glucose; Blood Pressure; Citrates; Citric Acid; Cross-Over Studies; | 1995 |
Coenzyme Q10 in essential hypertension.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Cholesterol; Cholesterol, HDL; Co | 1994 |
Amlodipine and haemodynamic effects of cyclo-oxygenase inhibition.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Amlodipine; Biomarkers; Blood Pressure; Creatinine | 1995 |
The renin angiotensin aldosterone system and frusemide response in congestive heart failure.
Topics: Administration, Oral; Aged; Aldosterone; Captopril; Cross-Over Studies; Drug Therapy, Combination; F | 1995 |
[Endocrine effects of nicardipine on intraoperative hypertension under droperidol-fentanyl-ketamine (DFK) anesthesia].
Topics: Adult; Aged; Aldosterone; Anesthesia, Intravenous; Atrial Natriuretic Factor; Catecholamines; Droper | 1995 |
Stimulation of aldosterone by ACTH in normal and hypertensive pregnancy.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hypertension; Pre-E | 1995 |
Hormonal, blood pressure, and peritoneal transport response to short-term ACE inhibition.
Topics: Administration, Oral; Adult; Aldosterone; Biological Transport; Blood Pressure; Enalapril; Enalapril | 1994 |
Hemodynamic and biochemical effects of the AT1 receptor antagonist irbesartan in hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Body Weigh | 1995 |
The influence of salt intake on plasma calcitonin gene-related peptide in subjects with mild essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Calcitonin Gene-Related Peptide; Cross-Over S | 1994 |
Does lipophilicity of angiotensin converting enzyme inhibitors selectively influence autonomic neural function in human hypertension?
Topics: Aldosterone; Autonomic Nervous System; Blood Pressure; Catecholamines; Cold Temperature; Cross-Over | 1994 |
Crossover comparison of the effects of enalapril and captopril on potassium homeostasis in patients with mild hypertension.
Topics: Aldosterone; Blood Pressure; Captopril; Circadian Rhythm; Cross-Over Studies; Drug Administration Sc | 1994 |
Enhanced pressor responsiveness to norepinephrine in type II diabetes. Effect of ACE inhibition.
Topics: Adult; Aldosterone; Blood Pressure; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; | 1994 |
Effects of an angiotensin II receptor antagonist, TCV-116, on renal haemodynamics in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Bloo | 1994 |
Hemodynamic and neurohumoral effects of fish oil in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Blood Pressure | 1993 |
Salt sensitivity and the blood pressure response to verapamil.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hyp | 1994 |
Low plasma 19-hydroxyandrostenedione levels in patients with aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Androstenedione; Blood Pressure; Dexamet | 1993 |
Randomly allocated study of the effects of standard therapy versus ACE inhibition on micro-albuminuria in essential hypertension.
Topics: Adrenergic beta-Antagonists; Albuminuria; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blo | 1994 |
[The importance of studying the renin-angiotensin-aldosterone system in essential arterial hypertension in clinical practice. Activity of the renin-angiotensin-aldosterone system during treatment of hypertension with ACE-inhibitors and beta blockers].
Topics: Adult; Aldosterone; Cross-Over Studies; Enalapril; Female; Humans; Hypertension; Male; Metoprolol; M | 1994 |
Pressure-dependent, enhanced natriuretic response to low-dose, atrial natriuretic peptide infusion in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; | 1994 |
Hemodynamic and humoral effects of low-dose aspirin in treated and untreated essential hypertensive patients.
Topics: Adult; Aldosterone; Aspirin; Captopril; Cross-Over Studies; Double-Blind Method; Female; Hemodynamic | 1994 |
Urinary kallikrein and salt sensitivity in essential hypertensive males.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cross-Over Studies; Double-Blind Meth | 1994 |
Effects of atrial natriuretic factor infusion on plasma prorenin levels in hypertensive males.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Enzyme Precursors; Heart Rate; Humans | 1994 |
Antihypertensive and humoral effects of verapamil and lacidipine in combination in hypertensive patients.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridi | 1993 |
Amlodipine in ambulatory hypertensive patients: humoral and haemodynamic effects.
Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Aldosterone; Amlodipine; Blood Pressure; Cholesterol; F | 1993 |
Comparison of blood pressure and angiotensin responses to the renin inhibitor Ro 42-5892 and the angiotensin converting enzyme inhibitor enalapril in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood P | 1993 |
[Influence of chronic ketanserin therapy on blood pressure and certain humoral and metabolic factors in patients with mild to moderate primary essential hypertension].
Topics: Administration, Oral; Adult; Aldosterone; Cholesterol; Epinephrine; Female; Humans; Hypertension; Ke | 1993 |
Responses to converting enzyme and renin inhibition. Role of angiotensin II in humans.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captop | 1994 |
Divergent hemodynamic and hormonal responses to varying salt intake in normotensive subjects.
Topics: Adult; Age Factors; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Family Heal | 1993 |
Brain natriuretic peptide: natriuretic and endocrine effects in essential hypertension.
Topics: Aldosterone; Cyclic GMP; Half-Life; Homeostasis; Humans; Hypertension; Male; Middle Aged; Natriuresi | 1993 |
Endogenous erythropoietin and salt sensitivity of blood pressure in patients with essential hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Erythropoietin; Female; Humans; Hyper | 1993 |
Efficacy of manidipine in the treatment of hypertension with renal impairment: a multicenter trial.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Blood Urea Nitrogen; Calcium C | 1993 |
The role of atrial natriuretic peptide in the diuretic effect of Ca2+ entry blockers.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Diure | 1993 |
Metoclopramide blocks bromocriptine induced antihypertensive effect in hypertensive patients.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Bromocriptine; Dopamine Antagonists; Dopamine | 1995 |
Comparison of amlodipine and quinapril on ambulatory blood pressure and platelet function in hypertension.
Topics: Adult; Aged; Aldosterone; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Age | 1995 |
Effect of dexamethasone on plasma free dopamine: dopaminergic modulation in hypertensive patients.
Topics: Adult; Aldosterone; alpha-Methyltyrosine; Dexamethasone; Dopamine; Dopamine Agents; Epinephrine; Hum | 1995 |
Dopaminergic regulation of aldosterone secretion: its pathophysiologic significance in subsets of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Dopamine; Dopamine Antagonists; Female; | 1995 |
Effects of felodipine, metoprolol and their combination on blood pressure at rest and during exercise and on volume regulatory hormones in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Double-Blind Method; Drug Thera | 1995 |
'Captopril test', with blood pressure and peripheral renin as response variables in hypertensive patients with suspected renal artery stenosis.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure Determination; Ca | 1995 |
Improvement of insulin sensitivity by metformin treatment does not lower blood pressure of nonobese insulin-resistant hypertensive patients with normal glucose tolerance.
Topics: Adult; Aged; Alanine; Aldosterone; Blood Glucose; Blood Pressure; Body Weight; Cross-Over Studies; D | 1996 |
Active kallikrein response to changes in sodium-chloride intake in essential hypertensive patients.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cross-Over Studies; Double-Blind Meth | 1996 |
Quinapril ACE-inhibition effects on adrenergic parameters in moderate essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Catech | 1996 |
Left ventricular structural and functional characteristics in patients with renovascular hypertension, primary aldosteronism and essential hypertension.
Topics: Adult; Aldosterone; Echocardiography; Female; Heart Ventricles; Humans; Hyperaldosteronism; Hyperten | 1996 |
[Concentration of neuropeptide Y in serum of patients with primary hypertension].
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Endothelins; Female; Humans; Hypertension; Male | 1996 |
Behaviour of adrenomedullin during acute and chronic salt loading in normotensive and hypertensive subjects.
Topics: Adrenomedullin; Adult; Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Body F | 1996 |
Effects of magnesium on blood pressure and intracellular ion levels of Brazilian hypertensive patients.
Topics: Administration, Oral; Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Brazil; Cal | 1996 |
Glucose load and renal sodium handling in mild essential hypertension on different sodium intakes.
Topics: Adolescent; Adult; Aldosterone; C-Peptide; Cross-Over Studies; Diet, Sodium-Restricted; Double-Blind | 1996 |
Interruption of prolonged ramipril treatment in hypertensive patients: effects on the renin-angiotensin system.
Topics: Aldosterone; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhi | 1996 |
The effects of angiotensin II receptor blockade with losartan on systemic blood pressure and renal and extrarenal prostaglandin synthesis in women with essential hypertension.
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphen | 1995 |
[Selected components of the kallikrein-kinin system and of the renin-angiotensin-aldosterone system in offspring of parents with hypertension].
Topics: Adult; Aldosterone; Body Mass Index; Family Health; Female; Humans; Hypertension; Kallikrein-Kinin S | 1996 |
Effects of carbidopa and of intravenous saline infusion into normal and hypertensive subjects on urinary free and conjugated dopamine.
Topics: Adolescent; Adult; Aldosterone; Aromatic Amino Acid Decarboxylase Inhibitors; Atrial Natriuretic Fac | 1997 |
Circulating kallikreins in normotensive and hypertensive humans: effects of mineralocorticoid administration.
Topics: Adult; Aldosterone; Blood Pressure; Female; Fludrocortisone; Heart Rate; Humans; Hypertension; Kalli | 1997 |
The effects of long-term treatment on left ventricular hypertrophy in patients with essential hypertension: relation to changes in neurohumoral factors.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atrial | 1997 |
[Effect of 12-week treatment with amlodipine on plasma renin activity and adrenal cortex function in patients with essential hypertension].
Topics: Adult; Aldosterone; Amlodipine; Antihypertensive Agents; Female; Humans; Hydrocortisone; Hypertensio | 1997 |
Renin status does not predict the anti-hypertensive response to angiotensin-converting enzyme inhibition in African-Americans. Trandolapril Multicenter Study Group.
Topics: Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; | 1998 |
Responses of natriuretic peptides to acute and chronic salt loading in normotensive and hypertensive subjects.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Female; Humans; Hypertension; I | 1998 |
Circulating plasma prekallikrein and tissue kallikrein in normotensive and hypertensive humans: effects of angiotensin II infusion.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Infusions, Intravenous; Ka | 1998 |
Inhibition of neutral endopeptidase causes vasoconstriction of human resistance vessels in vivo.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Fac | 1998 |
Increased arterial distensibility in postmenopausal hypertensive women with and without hormone replacement therapy after acute administration of the ACE inhibitor moexipril.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Blood Pressure; Double-B | 1998 |
Metoclopramide and domperidone block the antihypertensive effect of bromocriptine in hypertensive patients.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Bromocriptine; Case-Control Studies; Cr | 1998 |
Effects of eprosartan versus enalapril in hypertensive patients on the renin-angiotensin-aldosterone system and safety parameters: results from a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group.
Topics: Acrylates; Adult; Aged; Aged, 80 and over; Aldosterone; Analysis of Variance; Angiotensin II; Angiot | 1999 |
Effects of spironolactone and angiotensin-converting enzyme inhibitor on left ventricular hypertrophy in patients with essential hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Drug Therapy, Combination; Ec | 1999 |
The state and responsiveness of the renin-angiotensin-aldosterone system in patients with type II diabetes mellitus.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Diabetes Mellitus, Type 2; Diet, Sodium-Restricted; Female | 1999 |
Angiotensin II stimulates left ventricular hypertrophy in hypertensive patients independently of blood pressure.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Data Interpretation, Statistical; Dose-Response | 1999 |
[The effect of reduced sodium intake on blood pressure, body weight, renin, aldosterone, catecholamines, cholesterol and triglycerides. A meta-analysis].
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Catecholamines; Cholesterol; Diet, Sodium-Res | 1999 |
Dose-response efficacy of valsartan, a new angiotensin II receptor blocker.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihyperten | 1999 |
Acute hypotensive, natriuretic, and hormonal effects of nifedipine in salt-sensitive and salt-resistant black normotensive and hypertensive subjects.
Topics: Adult; Aldosterone; Antihypertensive Agents; Black People; Blood Pressure; Calcium Channel Blockers; | 1999 |
Plasma human atrial natriuretic peptide, endothelin-1, aldosterone and plasma-renin activity in pregnancy-induced hypertension.
Topics: Adolescent; Adult; Aldosterone; Atrial Natriuretic Factor; Endothelin-1; Female; Humans; Hypertensio | 1999 |
Altered adrenal sensitivity to angiotensin II in low-renin essential hypertension.
Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin II; Black People; Demography; Female; Humans; Hypert | 1999 |
Raised aldosterone to renin ratio predicts antihypertensive efficacy of spironolactone: a prospective cohort follow-up study.
Topics: Aldosterone; Anti-Inflammatory Agents; Antihypertensive Agents; Female; Fludrocortisone; Follow-Up S | 1999 |
Effects of the nonpeptide V(1) vasopressin receptor antagonist SR49059 in hypertensive patients.
Topics: Administration, Oral; Adult; Aldosterone; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopr | 1999 |
Aldosterone synthase gene (CYP11B2) C-344T polymorphism in Caucasians from the Berlin Salt-Sensitivity Trial (BeSST).
Topics: Adult; Aldosterone; Alleles; Angiotensinogen; Anthropometry; Blood Pressure; Cross-Over Studies; Cyt | 1999 |
Modification of intracellular calcium and plasma renin by dietary calcium in men.
Topics: Adult; Aldosterone; Biomarkers; Blood Platelets; Blood Pressure; Calcitriol; Calcium; Calcium, Dieta | 1999 |
Impact of aldosterone on left ventricular structure and function in young normotensive and mildly hypertensive subjects.
Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hypertension; Mal | 2000 |
Trandolapril does not improve insulin sensitivity in patients with hypertension and type 2 diabetes: a double-blind, placebo-controlled crossover trial.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; C | 2000 |
Renal haemodynamics and sodium excretory capacity during urapidil treatment in patients with essential hypertension.
Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Biomarkers; Ca | 2000 |
Antihypertensive effect of valyl-tyrosine, a short chain peptide derived from sardine muscle hydrolyzate, on mild hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Dipeptides; Dou | 2000 |
Efficacy of candesartan cilexetil alone or in combination with amlodipine and hydrochlorothiazide in moderate-to-severe hypertension. UK and Israel Candesartan Investigators.
Topics: Aldosterone; Amlodipine; Analysis of Variance; Antihypertensive Agents; Benzimidazoles; Biphenyl Com | 2000 |
Treatment of familial hyperaldosteronism type I: only partial suppression of adrenocorticotropin required to correct hypertension.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hyperal | 2000 |
The effects of verapamil SR and bisoprolol on reducing the sympathetic nervous system's activity.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Bisoprolol; Blood Pressure; Calcium Channel Blockers; Endo | 2000 |
Hemodynamic, hormone, and urinary effects of adrenomedullin infusion in essential hypertension.
Topics: Adrenomedullin; Adult; Aldosterone; Atrial Natriuretic Factor; Creatinine; Cross-Over Studies; Cycli | 2000 |
Proximal sodium reabsorption: An independent determinant of blood pressure response to salt.
Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Electrolytes; Fem | 2000 |
Dose response effect of conjugated equine oestrogen on blood pressure in postmenopausal women with hypertension.
Topics: Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Cross-Over Stu | 2000 |
C825T polymorphism of the G protein beta(3)-subunit and antihypertensive response to a thiazide diuretic.
Topics: Adult; Age Factors; Aldosterone; Alleles; Antihypertensive Agents; Blood Pressure; Diuretics; Female | 2001 |
Adverse cardiac effects of salt with fludrocortisone in hypertension.
Topics: Aldosterone; Anti-Inflammatory Agents; Echocardiography; Electrocardiography; Electrolytes; Female; | 2001 |
Absence of D147E mutation of CYP11B2 gene in hypertensive patients with increased corticosterone and aldosterone production.
Topics: Aged; Aldosterone; Corticosterone; Cytochrome P-450 CYP11B2; Exons; Female; Genotype; Humans; Hypert | 2001 |
Effect of salt intake on endothelium-derived factors in a group of patients with essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure Monitoring, Ambu | 2001 |
Effect of short-term losartan treatment in patients with primary aldosteronism and essential hypertension.
Topics: Administration, Oral; Age Factors; Aldosterone; Angiotensin Receptor Antagonists; Antihypertensive A | 2001 |
Performance of the basal aldosterone to renin ratio and of the renin stimulation test by furosemide and upright posture in screening for aldosterone-producing adenoma in low renin hypertensives.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Area Under Curve; Case-Control Studies; Diuret | 2001 |
Importance of the renin system for determining blood pressure fall with acute salt restriction in hypertensive and normotensive whites.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hyperten | 2001 |
Role of weight loss and polyunsaturated fatty acids in improving metabolic fitness in moderately obese, moderately hypertensive subjects.
Topics: Aldosterone; Blood Pressure; Body Composition; Dietary Fats; Fatty Acids; Fatty Acids, Omega-3; Fatt | 2001 |
Inhibitory effect of telmisartan on the blood pressure response to angiotensin II challenge.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme | 2001 |
Evaluation of plasma levels of renin-aldosterone and blood pressure in women over 35 years treated with new oral contraceptives.
Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Contraceptives, Oral; Drug Evaluation; Ethinyl Estr | 2001 |
Angiotensinogen gene core promoter variants and non-modulating hypertension.
Topics: Adult; Aldosterone; Angiotensinogen; Angiotensins; Genetic Linkage; Genotype; Humans; Hypertension; | 2001 |
Omapatrilat versus lisinopril: efficacy and neurohormonal profile in salt-sensitive hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood | 2001 |
Long-term effects of olmesartan, an Ang II receptor antagonist, on blood pressure and the renin-angiotensin-aldosterone system in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Antihyper | 2001 |
Spironolactone abolishes the relationship between aldosterone and plasminogen activator inhibitor-1 in humans.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Diuretics; Do | 2002 |
Angiotensinogen genotype affects renal and adrenal responses to angiotensin II in essential hypertension.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Antihypertens | 2002 |
Aldosterone synthase (CYP11B2) -344 C/T polymorphism is related to antihypertensive response: result from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin Receptor Antagonists; Antihypertensive Agents; | 2002 |
Amiloride, a specific drug for hypertension in black people with T594M variant?
Topics: Aldosterone; Amiloride; Amino Acid Substitution; Atrial Natriuretic Factor; Black People; Blood Pres | 2002 |
Effects of beta-adrenoreceptor blocking drugs on plasma volume. Renin and aldosterone as components of their antihypertensive action.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Antihypertensive Agents; Clinical Trials as Topic; | 1976 |
Long term non-selective and cardioselective beta-receptor blockade in hypertensive patients. Effects on circulatory parameters, catecholamines and renin activity under basal conditions and in connection with exercise and hypoglycemia.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Glucose; Blood Pressure; Clinical Trial | 1976 |
[The renin-aldosterone system in essential hypertension--hypotensive action of beta adrenergic blocking agents and variation of the renin-aldosterone system (author's transl)].
Topics: Adrenergic beta-Antagonists; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Met | 1977 |
Labetalol in the treatment of severe essential hypertension: relationship between arterial blood pressure, plasma catecholamines, plasma renin activity, plasma aldosterone and body weight.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Pressure; | 1979 |
[Treatment of essential hypertension with propranolol (author's transl)].
Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Clinical Trials as Topic; Creatinine; Cyclic AMP; F | 1976 |
Reduction of plasma renin activity by inhibition of the fatty acid cyclooxygenase in human subjects: independence of sodium retention.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Clinical Trials as Topic; Creatinine; Cycloox | 1979 |
Hormonal changes with long-term converting-enzyme inhibition by captopril in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; B | 1979 |
[Effect of chronic beta-adrenergic blockade on blood pressure and release of renin, aldosterone and cortisol in essential hypertension (author's transl)].
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Circadian Rhythm; Clinical Trials a | 1975 |
Spironolactone and hydrochlorothiazide in normal-renin and low-renin essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; H | 1977 |
Mineralocorticoid hypertension in childhood.
Topics: 18-Hydroxydesoxycorticosterone; Adolescent; Aldosterone; Blood Pressure; Child, Preschool; Clinical | 1977 |
Effect of minoxidil on blood pressure and hemodynamics in severe hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Drug Therapy, Combinat | 1977 |
Long term treatment of moderate hypertension with the beta1-receptor blocking agent metoprolol. I. Effect on maximal working capacity, plasma catecholamines and renin, Urinary aldosterone, blood pressure and pulse rate under basal conditions.
Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Clinical Trials as Topic; Epinephrine; Hemodynam | 1977 |
Relationship of plasma renin activity and aldosterone levels with hemodynamic functions in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Blood Volume; Blood Volume Determination; Cardiac Output; Cardia | 1977 |
Renin-aldosterone profiling in hypertension.
Topics: Aldosterone; Angiotensin II; Benzothiadiazines; Clinical Trials as Topic; Diagnosis, Differential; D | 1977 |
[Systematic analysis of various blood pressure regulating factors in diabetes mellitus].
Topics: Aldosterone; Catecholamines; Clinical Trials as Topic; Creatinine; Diabetes Complications; Diabetes | 1977 |
Response of blood pressure and the renin-angiotensin-aldosterone axis to hypotensive therapy: comparison of propranolol with spironolactone.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Female; Furosemide; Hu | 1977 |
Alpha and beta adrenergic blockade with orally administered labetalol in hypertension. Studies on blood volume, plasma renin and aldosterone and catecholamine excretion.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Volume; Body Weight; Chlorthalidone; Clinical Trials | 1978 |
[Spironolactone-induced changes of the renin-angiotensin-aldosterone system and blood pressure lowering in essential hypertension].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Humans; Hype | 1977 |
Relationships of renin and aldosterone to antihypertensive effects of spironolactone and propranolol.
Topics: Adult; Aldosterone; Antihypertensive Agents; Clinical Trials as Topic; Female; Humans; Hypertension; | 1978 |
Hydrochlorothiazide and spironolactone in hypertension.
Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Clinical Trials as Topic; Cr | 1979 |
The renin-aldosterone system in dihydralazine therapy during hypertensive pregnancy.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Dihydralazine; Electrolytes; Female; H | 1978 |
A comparative study of the effects of oxprenolol versus propranolol in essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Hum | 1979 |
Effects of beta 1-selective and non-selective beta-blockade on blood pressure, plasma renin activity and plasma aldosterone in hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; | 1979 |
Once-daily metoprolol in primary hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Drug Administration Schedule; Electrol | 1979 |
Haemodynamic effects of captopril in hypertensive patients: comparison with saralasin.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Captopril; Cardiac Output; Clinical Trials as Topic; He | 1979 |
Effect of increasing doses of labetalol on blood pressure, plasma renin activity and aldosterone in hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Etha | 1979 |
[Correlation between plasma volume and plasma renin activity, aldosteronemia, blood electrolytes and arterial pressure in a group of randomized hypertensives].
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Electrolytes; Female; Humans; Hypertension; Male; Mi | 1979 |
Clonidine in primary hypertension: effects on blood pressure, plasma renin activity, plasma and urinary aldosterone.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Humans; Hypertensio | 1977 |
The influence of sar1 ala8 angiotensin II (saralasin) on plasma aldosterone in hypertensive patients.
Topics: Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypertension, Reno | 1979 |
The renin-aldosterone system and thiazide-induced depletion of total body potassium in essential hypertension.
Topics: Adult; Aged; Aldosterone; Body Weight; Chlorothiazide; Drug Therapy, Combination; Female; Humans; Hy | 1978 |
Controlled treatment of primary hypertension with propranolol and spironolactone. A crossover study with special reference to initial plasma renin activity.
Topics: Adult; Aldosterone; Angiotensin II; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hum | 1976 |
Propranolol, renin and hypertension: a review.
Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Child; Clinical Trials as Topic; Female; Human | 1976 |
Effect of blood pressure angiotensin II and aldosterone concentrations during treatment of severe hypertension with intravenous labetalol: comparison with propranolol.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Ethanolamines; Heart Rate; Hu | 1976 |
[Antihypertensive effects of ecarazine hydrochloride in essential hypertension and its action on the renin-aldosterone system].
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Clinical Trials as Topic; Female; Heterocyclic Co | 1976 |
Differential effects of acute and chronic beta-adrenoreceptor blockade on blood pressure and the renin-angiotensin-aldosterone system in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Clinical Trials as Topic; Humans; Hypertension; Male; Pindolol; | 1976 |
Effect of beta1-receptor blockade (Metoprolol, Selokenr) on blood pressure, pulse rate, plasma catecholamines, renin activity and urinary aldosterone.
Topics: Aldosterone; Blood Pressure; Catecholamines; Clinical Trials as Topic; Drug Evaluation; Humans; Hype | 1976 |
Anti-hypertensive adrenergic-blocking agents: effects on sodium balance, the renin-angiotensin system and haemodynamics.
Topics: Adult; Aldosterone; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Clonidine; Female; Gua | 1975 |
Effect of sotalol on haemodynamics and renin-angiotensin-aldosterone system in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Female; Heart Rate; Humans | 1976 |
Effect of high dose spironolactone and chlorthalidone in essential hypertension: relation to plasma renin activity and plasma volume.
Topics: Adult; Aldosterone; Body Weight; Chlorthalidone; Female; Humans; Hypertension; Male; Middle Aged; Pl | 1975 |
Effects of intravenous labetalol on blood pressure, angiotensin II and aldosterone in hypertension: comparison with propranolol.
Topics: Aldosterone; Angiotensin II; Depression, Chemical; Ethanolamines; Heart Rate; Humans; Hypertension; | 1976 |
Aldosterone and renin in essential hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adult; Age Factors; Aldosterone; Angiotensin II; Clinical Trials as | 1975 |
Intrapatient comparison of treatment with chlorthalidone, spironolactone and propranolol in normoreninemic essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Chlorthalidone; Clinical Trials as Topic; Creatinin | 1975 |
Antagonism of the effects of furosemide by indomethacin in normal and hypertensive man.
Topics: Aldosterone; Blood Pressure; Clinical Trials as Topic; Drug Interactions; Furosemide; Humans; Hypert | 1975 |
Contraceptive steroids and hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Deoxycholic Acid; Female; Humans; | 1975 |
Twenty-four hour blood pressure effect of once-daily lisinopril, enalapril, and placebo in patients with mild to moderate hypertension.
Topics: Adult; Aged; Aldosterone; Ambulatory Care; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; | 1992 |
Comparative effects of dopaminergic agonists on cardiovascular, renal, and renin-angiotensin systems in hypertensive patients.
Topics: Aldosterone; Blood Pressure; Bromocriptine; Creatinine; Dopamine Agents; Female; Heart Rate; Hemodyn | 1992 |
Short-term strenuous exercise training: effects on blood pressure and hormonal levels in mild hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Chromogranin A; Chromogranins; Epinephrine; Exercise Therapy; Fo | 1992 |
Long-term diuretic therapy: effects of dose reduction on antihypertensive efficacy and counterregulatory systems.
Topics: Aldosterone; Benzothiadiazines; Blood Pressure; Body Weight; Diuretics; Dose-Response Relationship, | 1992 |
Hemodynamic and humoral effects of the novel calcium antagonist Ro 40-5967 in patients with hypertension.
Topics: Aldosterone; Benzimidazoles; Calcium Channel Blockers; Catecholamines; Drug Administration Schedule; | 1992 |
Effect of atrial natriuretic peptide (8-33-Met ANP) in patients with hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Bradycardia; Diuresis; Double-Blind M | 1992 |
Effects of sustained-release nicardipine on regression of left ventricular hypertrophy in systemic hypertension.
Topics: Aldosterone; Blood Pressure; Cardiomegaly; Delayed-Action Preparations; Double-Blind Method; Echocar | 1992 |
[Several indicators of hormonal homeostasis (hypophysis--gonads) in patients with hypertension].
Topics: Adult; Aldosterone; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Gonadotropins, Pituitary | 1992 |
Comparisons of long-term effects between converting enzyme inhibitors and conventional therapy in treating mild to moderate hypertension.
Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Electroca | 1991 |
Single administration of captopril and combined use with beta-blocker and/or thiazide diuretic in the treatment of essential hypertension.
Topics: Acebutolol; Adrenergic beta-Antagonists; Aldosterone; Benzothiadiazines; Blood Pressure; Captopril; | 1991 |
Vascular pressor responses in treated and untreated essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; D | 1990 |
Catecholamines and the renin-angiotensin-aldosterone system during treatment with felodipine ER or hydrochlorothiazide in essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Delayed-Action Preparations; Double-Blind | 1991 |
Hemodynamic and humoral interactions between perindopril and indomethacin in essential hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; D | 1991 |
Short-term effects of atenolol and nifedipine on atrial natriuretic peptide, plasma renin activity, and plasma aldosterone in patients with essential hypertension.
Topics: Adult; Aldosterone; Atenolol; Atrial Natriuretic Factor; Female; Humans; Hypertension; Male; Middle | 1991 |
Isradipine in the treatment of hypertension. Some additional effects observed during a one-year study.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Echocardiography; Exercise; Femal | 1991 |
Acute and sustained changes in sodium balance during nifedipine treatment in essential hypertension.
Topics: Aged; Aldosterone; Analysis of Variance; Atrial Natriuretic Factor; Blood Pressure; Delayed-Action P | 1991 |
Atrial natriuretic peptide inhibits the aldosterone response to metoclopramide in patients with glomerular disease and essential hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Female; Glomerulonephritis; Heart Rat | 1991 |
Dietary sodium and inhibition of neutral endopeptidase 24.11 in essential hypertension.
Topics: Adult; Aldosterone; Analysis of Variance; Atrial Natriuretic Factor; Blood Pressure; Creatine; Heart | 1991 |
Effects of antihypertensive drugs on glomerular function in normotensive and hypertensive subjects: hormonal aspects.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Dietary Carbohydrates; Dietary Proteins; Enalapril; F | 1991 |
Glucose tolerance and insulin secretion in essential hypertension after treatment with an angiotensin converting enzyme inhibitor.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Cilazapril; Female; Glucose To | 1991 |
Response to the cold pressor test in normotensive and hypertensive patients.
Topics: Aldosterone; Blood Pressure; Cold Temperature; Humans; Hypertension; Posture; Reflex; Renin | 1991 |
The influence of oral potassium citrate/bicarbonate on blood pressure in essential hypertension during unrestricted salt intake.
Topics: Adult; Aldosterone; Bicarbonates; Blood Pressure; Citrates; Female; Humans; Hypertension; Male; Midd | 1991 |
Effects of carvedilol on renal function.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Carbazoles; Carvedilol; Double-Blin | 1990 |
Sodium restriction in hypertensive patients treated with a converting enzyme inhibitor and a thiazide.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Double-Blind Metho | 1991 |
Co-dergocrine mesylate inhibits the increase in plasma catecholamines caused by nifedipine in essential hypertension.
Topics: Aldosterone; Catecholamines; Dihydroergotoxine; Drug Therapy, Combination; Female; Humans; Hypertens | 1990 |
Effect of the circulating renin-angiotensin system on prolactin release in humans.
Topics: Adenoma; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Circadian Rhythm; Enalapril; Humans; | 1990 |
Effects of captopril and minoxidil on left ventricular hypertrophy in resistant hypertensive patients: a 6 month double-blind comparison.
Topics: Adult; Aged; Aldosterone; Captopril; Cardiomegaly; Double-Blind Method; Echocardiography; Humans; Hy | 1990 |
Inverse relationship between upright plasma renin activity and twenty-four hour blood pressure variability in borderline hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Male; Postur | 1990 |
The effects of nicardipine on sodium and calcium metabolism in hypertensive patients: a chronic study.
Topics: Administration, Oral; Adult; Aged; Aldosterone; Calcium; Double-Blind Method; Female; Humans; Hypert | 1990 |
Comparison of the renal effects of dilevalol and carteolol in patients with mild to moderate essential hypertension.
Topics: Adult; Aldosterone; Blood Proteins; Carteolol; Female; Glomerular Filtration Rate; Hemodynamics; Hum | 1990 |
Antihypertensive and renal effects of enalapril and slow-release verapamil in essential hypertension. A double-blind, randomized study.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Delayed-Action Preparations; Double-Blind Method | 1990 |
Efficacy of nicardipine slow release (SR) on hypertension, potassium balance and plasma aldosterone in idiopathic aldosteronism.
Topics: Administration, Oral; Adult; Aldosterone; Blood Pressure; Delayed-Action Preparations; Female; Human | 1990 |
Ketanserin and captopril interaction in the treatment of essential hypertensives.
Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Captopril; Double-Blind Method; Drug Therapy, Combi | 1990 |
Effect of ketanserin in primary aldosteronism.
Topics: Aldosterone; Blood Pressure; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Ketanserin; P | 1985 |
Moderate sodium restriction, angiotensin converting enzyme inhibition, and thiazide diuretic in the management of essential hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Diet, So | 1989 |
[Effect of a calcium inhibitor, nicardipine, on aldosterone secretion in primary hyperaldosteronism].
Topics: Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hypera | 1989 |
Prolonged decrease in blood pressure after atrial natriuretic peptide infusion in essential hypertension: a new anti-pressor mechanism?
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Diet, Sodium-Restricted; Female | 1989 |
Increase of plasma atrial natriuretic peptide levels after sublingual administration of nifedipine in essentially hypertensive patients.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Heart Rate; Humans; Hypertension; Mid | 1989 |
Fosenopril, an angiotensin-converting enzyme inhibitor, and propranolol: comparative effects at rest and exercise on blood pressure, hormonal variables, and plasma potassium in essential hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; Exercise | 1989 |
Acute calcium entry blockade inhibits the blood pressure but not the hormonal responses to angiotensin II.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; | 1989 |
Comparison of intravenous dilevalol with placebo in moderate hypertension.
Topics: Aldosterone; Atrial Natriuretic Factor; Catecholamines; Cyclic GMP; Double-Blind Method; Humans; Hyp | 1989 |
Captopril versus enalapril maleate: a comparison of antihypertensive and hormonal effects.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopr | 1985 |
Influence of food on acute and chronic effects of captopril in essential hypertensive patients.
Topics: Adult; Aldosterone; Captopril; Fasting; Female; Food; Hemodynamics; Humans; Hypertension; Male; Midd | 1985 |
Therapeutic value of calcium antagonists in autonomous hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Fema | 1989 |
Does hormone analysis predict the antihypertensive response of basic medical treatment?
Topics: Adolescent; Adult; Aldosterone; Clinical Trials as Topic; Dinoprost; Dinoprostone; Female; Humans; H | 1989 |
The haemodynamic and hormonal responses after clonidine occur independently of sedation in essential hypertension.
Topics: Adult; Aldosterone; Clonidine; Epinephrine; Female; Hemodynamics; Hormones; Humans; Hypertension; Hy | 1989 |
Hypertensive dysregulation and its modification by calcium channel blockade in nonoliguric renal failure.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Catecholamines; | 1989 |
Antihypertensive and humoral effects of nifedipine in essential hypertension uncontrolled by hydrochlorothiazide alone.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therap | 1989 |
Preliminary observations of the acute effects of selective serum thromboxane inhibition and angiotensin converting enzyme inhibition on blood pressure and renal hemodynamics in hypertensive humans.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Clinical Tr | 1989 |
Crossover design for the dose determination of an angiotensin converting enzyme inhibitor in hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Bl | 1989 |
Reversal of diuretic-induced secondary hyperaldosteronism and hypokalemia by trilostane, an inhibitor of adrenal steroidogenesis.
Topics: Aldosterone; Blood Pressure; Dihydrotestosterone; Diuretics; Double-Blind Method; Female; Humans; Hy | 1989 |
Mechanism of impaired natriuretic response to furosemide during prolonged therapy.
Topics: Adult; Aged; Aldosterone; Body Weight; Chlorothiazide; Furosemide; Humans; Hypertension; Male; Middl | 1989 |
[Clinical pharmacology of a single doses of captopril and enalapril. Controlled study in subjects with essential hypertension].
Topics: Adult; Aged; Aldosterone; Blood Pressure; Captopril; Clinical Trials as Topic; Double-Blind Method; | 1987 |
[Definition and consequences of blocking the renin-angiotensin system by converting enzyme inhibition].
Topics: Adult; Aged; Aldosterone; Blood Pressure; Drug Administration Schedule; Enalapril; Female; Humans; H | 1987 |
Antihypertensive effect of enalapril in essential hypertension: role of prostacyclin.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aldosterone; Enalapril; Epoprostenol; Female; Humans; Hyp | 1987 |
Unrelated responses of brachial artery hemodynamics and renin-angiotensin system to acute converting enzyme inhibition by enalaprilat in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Brachial Artery; Clini | 1988 |
[Effects of phenylephrine on atrial natriuretic factor and the renin-aldosterone axis in normal patients and essential hypertensive patients].
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Diuresis; Humans; Hyperte | 1988 |
Humoral effects of metoclopramide and domperidone in normal subjects and in hypertensive patients.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Domperidone; Female; Humans; Hydrocortisone; Hypert | 1988 |
Studies with fenoldopam, a dopamine receptor DA1 agonist, in essential hypertension.
Topics: Adult; Aldosterone; Benzazepines; Blood Pressure; Chromium Radioisotopes; Fenoldopam; Glomerular Fil | 1986 |
Fenoldopam: effect on aldosterone secretion.
Topics: Aldosterone; Benzazepines; Double-Blind Method; Fenoldopam; Humans; Hypertension; Metoclopramide; Mi | 1986 |
Renin and beta-blockade: prorenin and aldosterone may explain the controversy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Dou | 1986 |
Effect of fenoldopam on the aldosterone response to metoclopramide in man.
Topics: Aldosterone; Benzazepines; Clinical Trials as Topic; Double-Blind Method; Fenoldopam; Humans; Hypert | 1986 |
The clinical pharmacology of bopindolol, a new long-acting beta-adrenoceptor antagonist, in hypertension.
Topics: Adrenergic beta-Antagonists; Aldosterone; Cardiac Output; Clinical Trials as Topic; Epinephrine; Hea | 1987 |
Renal haemodynamic and neurohumoral responses to urapidil in hypertensive man.
Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Clinical Trial | 1988 |
Ketanserin and prazosin: a comparison of antihypertensive and biochemical effects.
Topics: Adult; Aldosterone; Blood Pressure; Cholesterol; Drug Evaluation; Female; Heart Rate; Humans; Hypert | 1986 |
Systemic and renal hemodynamic effects of celiprolol in essential hypertensives.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Celiprolol; Clinical Trials as Topic; D | 1988 |
Effects of fosenopril, a once-daily angiotensin-converting enzyme inhibitor, on resting and exercise-induced changes of blood pressure, hormonal variables, and plasma potassium in essential hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Drug Administration Schedule; | 1988 |
Effects of celiprolol on plasma renin, aldosterone, norepinephrine and epinephrine in primary hypertension.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Celiprolol; Double-Blind Method; Epinephrine; Fem | 1988 |
Inhibition of the aldosterone response to sodium depletion in man by stimulation of dopamine DA2 receptors.
Topics: Aged; Aldosterone; Dihydroergotoxine; Female; Humans; Hypertension; Male; Middle Aged; Receptors, Do | 1988 |
Humoral effects of long-term oral enalapril therapy.
Topics: Administration, Oral; Aldosterone; Angiotensin II; Blood Pressure; Blood Specimen Collection; Clinic | 1986 |
Time course of changes in blood pressure, aldosterone and body fluids during enalapril treatment: a double-blind randomized study vs hydrochlorothiazide plus propranolol in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Body Fluids; Clinical Trials as Topic; Double-Blind Method; Drug | 1986 |
The pharmacodynamics and dose-response relationships of the angiotensin converting enzyme inhibitor, cilazapril, in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Autonomic Nervous System; Blood | 1986 |
The haemodynamic and humoral effects of treatment for one month with the angiotensin converting enzyme inhibitor perindopril in salt replete hypertensive patients.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Age | 1987 |
Moderate sodium restriction in hypertensive subjects: renal effects of ACE-inhibition.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diet, Sodium-Restricte | 1987 |
Enhanced response of plasma prolactin to metoclopramide during chronic converting enzyme inhibition.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Enalapril; Female; Hum | 1987 |
Effects of moderate low sodium/high potassium diet on essential hypertension: results of a comparative study.
Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Clinical Trials as Topic; Diet; Double-Blind Method | 1988 |
Hormone, calcium and blood pressure relationships in primary hyperparathyroidism.
Topics: Aged; Aldosterone; Catecholamines; Female; Hormones; Humans; Hypercalcemia; Hyperparathyroidism; Hyp | 1988 |
Antihypertensive response to ketanserin: influence of race and weight.
Topics: Adult; Aged; Aldosterone; Black People; Blood Pressure; Body Weight; Female; Heart Rate; Humans; Hyp | 1988 |
Inducing hyperkalemia by converting enzyme inhibitors and heparin.
Topics: Acidosis; Acute Kidney Injury; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Drug Therapy, | 1988 |
Intracellular sodium and the response to nitrendipine or atenolol in African blacks.
Topics: Adult; Africa; Aldosterone; Atenolol; Black People; Blood Pressure; Double-Blind Method; Erythrocyte | 1988 |
The combination of prazosin and verapamil in the treatment of essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Drug Therapy, Combination; Female; Heart Rate; H | 1988 |
Captopril and nifedipine in combination for moderate to severe essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Captopril; Drug Administration Schedule; Drug | 1987 |
Multiple oral doses of nicardipine, a calcium-entry blocker: effects on renal function, plasma renin activity, and aldosterone concentration in mild-to-moderate essential hypertension.
Topics: Adult; Aldosterone; Clinical Trials as Topic; Female; Glomerular Filtration Rate; Hemodynamics; Huma | 1987 |
Plasma renin activity does not predict the antihypertensive efficacy of chlorthalidone.
Topics: Adult; Aldosterone; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; E | 1987 |
Acute and chronic ketanserin in essential hypertension: antihypertensive mechanisms and pharmacokinetics.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Electrocardiography; Female; Heart Rate; Humans; | 1987 |
Haemodynamic (systemic and renal) and humoral interactions between nicardipine and domperidone in hypertensives.
Topics: Adult; Aldosterone; Domperidone; Drug Interactions; Female; Glomerular Filtration Rate; Heart Rate; | 1987 |
The effect of reduced alcohol consumption on blood pressure: a randomised, controlled, single blind study.
Topics: Adult; Alcohol Drinking; Aldosterone; Blood Pressure; Clinical Trials as Topic; Epinephrine; Humans; | 1987 |
Atenolol or propranolol in hypertensive patients poorly controlled on captopril and frusemide.
Topics: Aged; Aldosterone; Atenolol; Blood Pressure; Captopril; Clinical Trials as Topic; Creatinine; Double | 1987 |
Guanfacine as monotherapy for systemic hypertension.
Topics: Adult; Aged; Aldosterone; Cholesterol; Clinical Trials as Topic; Double-Blind Method; Drug Evaluatio | 1986 |
Effects of combined therapy with amiloride and hydrochlorothiazide on plasma and total body potassium, blood pressure, and the renin-angiotensin-aldosterone system in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Amiloride; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Drug | 1986 |
Prostaglandin E2 analogue elicits renal and hormonal compensatory mechanisms in human hypertension.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressu | 1986 |
Selected mechanisms of diuretic-induced electrolyte changes.
Topics: Aldosterone; Amiloride; Clinical Trials as Topic; Diuresis; Diuretics; Double-Blind Method; Humans; | 1986 |
Hypokalemia in thiazide-treated systemic hypertension.
Topics: Aldosterone; Amiloride; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydrochlorothia | 1986 |
Neurohormonal responses to antihypertensive treatment with captopril or hydrochlorothiazide.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Dopamine; Female; Humans; Hydrochlorothiazide; Hypert | 1986 |
[Increased endogenous dopamine activity in diabetes mellitus. Inhibition of plasma renin activity, aldosterone and prolactin secretion].
Topics: Aged; Aldosterone; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dopamine; Humans; Hypertensi | 1986 |
The influence of ibuprofen, diclofenac and sulindac on the blood pressure lowering effect of hydrochlorothiazide.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Creatinine; Diclofenac; Drug The | 1987 |
Potassium and norepinephrine- or angiotensin-mediated pressor control in pre-hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Norepinephri | 1987 |
Potassium supplementation in hypertensive patients with diuretic-induced hypokalemia.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; | 1985 |
Effect of captopril and hydrochlorothiazide on the response to pressor agents in hypertensives.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Dru | 1985 |
Effects of potassium on sodium balance, renin, noradrenaline and arterial pressure.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Condiments; Female; Heart Rate; Humans; Hyperten | 1985 |
Interference on metabolism induced by muzolimine and chlorthalidone in type II hypertensive diabetics.
Topics: Aldosterone; Blood Glucose; Blood Pressure; Carbohydrate Metabolism; Chlorthalidone; Clinical Trials | 1985 |
The sodium intake modifies the renin-aldosterone and blood pressure changes associated with moderately low energy diets.
Topics: Aldosterone; Blood Pressure; Diet, Reducing; Diet, Sodium-Restricted; Humans; Hypertension; Male; Mi | 1985 |
[Evaluation of the antihypertensive effect of capsule and tablet forms of nifedipine in moderate hypertension].
Topics: Aldosterone; Capsules; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertension; Nifedipi | 1985 |
[Esmaloride--a new potassium neutral diuretic combination. Clinical pharmacologic properties].
Topics: Aldosterone; Amiloride; Blood Glucose; Blood Pressure; Body Weight; Creatinine; Drug Combinations; F | 1985 |
Effect of verapamil on renal plasma flow, glomerular filtration rate and plasma angiotensin II, aldosterone and arginine vasopressin in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Blood Pressure; Body Weight; Female; Glome | 1985 |
Beta-blockers and plasma renin activity in hypertension.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aldosterone; Benzothiadiazines; Blood Pressure; Crea | 1974 |
High blood pressure and oral contraceptives. Changes in plasma renin and renin substrate and in aldosterone excretion.
Topics: Aldosterone; Angiotensin II; Clinical Trials as Topic; Contraceptives, Oral; Ethinyl Estradiol; Fema | 1968 |
Effect of adrenocorticotropin on desoxycorticosterone, corticosterone and aldosterone excretion.
Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormo | 1969 |
[Variations in the renin-angiotensin-aldosterone system and in the antidiuretic hormone induced within 5 days by a contraceptive drug. Rapid action of a contraceptive drug on the hormones controlling water and salt metabolism].
Topics: Adult; Aldosterone; Angiotensin II; Clinical Trials as Topic; Contraceptives, Oral; Ethinyl Estradio | 1970 |
18-Hydroxy-deoxycorticosterone in human hypertension.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Blood Pressure; Catheteriz | 1971 |
Propranolol therapy in essential hypertension. Observations on predictability of therapeutic response.
Topics: Administration, Oral; Adult; Aged; Aldosterone; Blood Pressure; Cardiac Output; Creatinine; Dose-Res | 1974 |
Relation of age, diastolic pressure and known duration of hypertension to presence of low renin essential hypertension.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aging; Aldosterone; Blood Pressure; Clinical Trials | 1973 |
Treatment of low-renin essential hypertension. Comparison of spironolactone and a hydrochlorothiazide-triamterene combination.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; | 1974 |
[Clinical effect of a beta receptor blockader, oxprenolol, in hypertension--its relationship with renin-aldosterone activities].
Topics: Adolescent; Adult; Aldosterone; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle | 1974 |
Effects of acute and chronic administration of propranolol on blood pressure and plasma renin activity in hypertensive patients.
Topics: Adolescent; Adult; Aldosterone; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Diet, S | 1974 |
Total body potassium in long-term Lasix therapy.
Topics: Aldosterone; Clinical Trials as Topic; Diuresis; Furosemide; Humans; Hydrochlorothiazide; Hypertensi | 1974 |
A method for the simultaneous determination of the secretion rates of cortisol, 11-desoxycortisol, corticosterone, 11-desoxycorticosterone and aldosterone.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Carbon Isotopes; Child; Child, Pres | 1969 |
The postural plasma renin activity response in essential hypertension and primary hyperaldosteronism.
Topics: Adult; Aged; Aldosterone; Clinical Trials as Topic; Female; Humans; Hyperaldosteronism; Hypertension | 1969 |
3835 other studies available for aldosterone and Hypertension
Article | Year |
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A Chinese pedigree with glucocorticoid remediable aldosteronism.
Topics: Adult; Aldosterone; China; Cytochrome P-450 CYP11B2; Glucocorticoids; Humans; Hyperaldosteronism; Hy | 2021 |
Correlation between kidney sodium and potassium handling and the renin-angiotensin-aldosterone system in children with hypertensive disorders.
Topics: Adolescent; Aldosterone; Blood Pressure; Creatinine; Cross-Sectional Studies; Female; Humans; Hypert | 2022 |
The role of surgery in Conn's syndrome - a case of refractory hypertension secondary to an aldosterone secreting adenoma.
Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Male | 2021 |
The Effects of Verapamil, Hydralazine, and Doxazosin on Renin, Aldosterone, and the Ratio Thereof.
Topics: Aldosterone; Antihypertensive Agents; Doxazosin; Humans; Hydralazine; Hyperaldosteronism; Hypertensi | 2023 |
Prevalence of primary aldosteronism in type 2 diabetes mellitus and hypertension: A prospective study from Western India.
Topics: Adult; Aldosterone; Diabetes Mellitus, Type 2; Female; Humans; Hyperaldosteronism; Hypertension; Ind | 2022 |
[A Case of Pseudohypoaldosteronism Type Ⅱ (PHA2) Caused by a Novel Mutation of
Topics: Adaptor Proteins, Signal Transducing; Adult; Aldosterone; Female; Humans; Hypertension; Microfilamen | 2021 |
Hypertension with unilateral adrenal aldosterone and cortisol cosecreting adenoma: A case report.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Humans; Hydrocortisone; Hyperal | 2021 |
Screening Rates for Primary Aldosteronism Among Individuals With Hypertension Plus Hypokalemia: A Population-Based Retrospective Cohort Study.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; | 2022 |
First-in-Human Study of MANP: A Novel ANP (Atrial Natriuretic Peptide) Analog in Human Hypertension.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Female; Humans; Hypertension; M | 2021 |
Prediction of long-term biochemical cure in patients with unilateral primary hyperaldosteronism treated surgically based on the early post-operative plasma aldosterone value.
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Postoperative Period; Renin; R | 2022 |
Evaluation of Intra-Renal Stiffness in Patients with Primary Aldosteronism.
Topics: Adult; Aged; Aldosterone; Essential Hypertension; Female; Humans; Hyperaldosteronism; Hypertension; | 2022 |
Genetic Predictors of Salt Sensitivity of Blood Pressure: The Additive Impact of 2 Hits in the Same Biological Pathway.
Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Angiotensinogen; Blood Pressure; Estrogen Receptor be | 2021 |
Fibrin clot properties and fibrinolysis in patients with endocrine hypertension due to aldosterone or catecholamines excess.
Topics: Adrenal Gland Neoplasms; Aldosterone; Catecholamines; Fibrin; Fibrin Clot Lysis Time; Fibrinolysis; | 2022 |
Plasma aldosterone concentration is associated with white matter lesions in patients with primary aldosteronism.
Topics: Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin; Retrospectiv | 2022 |
Higher aldosterone is associated with increased renal impairment risk in patients with hypertension and abnormal glucose metabolism: a longitudinal study.
Topics: Aldosterone; Glomerular Filtration Rate; Glucose; Humans; Hypertension; Longitudinal Studies; Renal | 2022 |
Aldosterone and renin concentrations were abnormally elevated in a cohort of normotensive pregnant women.
Topics: Aldosterone; Blood Pressure; Female; Humans; Hypertension; Placenta; Pregnancy; Pregnancy Outcome; P | 2022 |
Screening Rate for Primary Aldosteronism Among Patients With Apparent Treatment-Resistant Hypertension: Retrospective Analysis of Current Practice.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Mass Scree | 2022 |
Suspected primary hyperreninism in a cat with malignant renal sarcoma and global renin-angiotensin-aldosterone system upregulation.
Topics: Aldosterone; Animals; Cat Diseases; Cats; Hyperaldosteronism; Hypertension; Kidney Neoplasms; Male; | 2022 |
Positive Association Between Plasma Aldosterone Concentration and White Matter Lesions in Patients With Hypertension.
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Magnetic Resonance Imaging; Ma | 2021 |
Enhanced performance of a modified diagnostic test of primary aldosteronism in patients with adrenal adenomas.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Aldosterone; Dexamethasone; Female; Humans | 2022 |
Th17/Treg imbalance in patients with primary hyperaldosteronism and resistant hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure Monitoring, Ambulatory; Forkhead Transcription Factors; | 2022 |
The neurobiology of childhood trauma-aldosterone and blood pressure changes in a community sample.
Topics: Adverse Childhood Experiences; Aldosterone; Blood Pressure; Humans; Hypertension; Renin; Renin-Angio | 2022 |
Salt-Sensitive Hypertension in GR
Topics: Adrenal Glands; Aldosterone; Animals; Corticosterone; Epoxide Hydrolases; Fatty Acids, Unsaturated; | 2021 |
Letter to editor on "Thirty-six-month results of laparoscopic-based renal denervation plus unilateral laparoscopic adrenalectomy for the treatment of patients with resistant hypertension caused by unilateral aldosterone-producing Adenoma".
Topics: Adenoma; Adrenalectomy; Aldosterone; Denervation; Humans; Hyperaldosteronism; Hypertension; Laparosc | 2022 |
Screening for primary aldosteronism in the diabetic population: a cohort study.
Topics: Aldosterone; Cohort Studies; Diabetes Mellitus, Type 2; Humans; Hyperaldosteronism; Hypertension; Ma | 2023 |
Higher Plasma Aldosterone Concentrations Are Associated With Elevated Risk of Aortic Dissection and Aneurysm: a Case-Control Study.
Topics: Aldosterone; Aortic Dissection; Case-Control Studies; Female; Humans; Hyperaldosteronism; Hypertensi | 2022 |
Salt Sensitivity of Blood Pressure and Aldosterone: Interaction Between the Lysine-specific Demethylase 1 Gene, Sex, and Age.
Topics: Aldosterone; Animals; Blood Pressure; Epigenesis, Genetic; Estrogens; Female; Histone Demethylases; | 2022 |
Apparent mineralocorticoid excess: A diagnosis beyond classical causes of severe hypertension in a child.
Topics: Aldosterone; Amiloride; Blood Pressure; Child, Preschool; Female; Humans; Hypertension; Hypokalemia; | 2022 |
MANP (M-Atrial Natriuretic Peptide) Reduces Blood Pressure and Furosemide-Induced Increase in Aldosterone in Hypertension.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Furosemide; Guanosine M | 2022 |
[Diagnosis and therapy of primary aldosteronism: new aspects].
Topics: Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hyperplasia; Hypert | 2022 |
Establishing Reference Ranges for Aldosterone, Renin and Aldosterone-to-Renin Ratio for Women in the Third-Trimester of Pregnancy.
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Pregnancy; Pregnancy Trimester | 2022 |
Syndromes of Pseudo-Hyperaldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Renin; Syndrome | 2022 |
Screening for primary aldosteronism is underutilised in patients with chronic kidney disease.
Topics: Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Renal Insufficiency, Chroni | 2022 |
Renin, aldosterone, the aldosterone-to-renin ratio, and incident hypertension among normotensive subjects from the general population.
Topics: Aldosterone; Biomarkers; Blood Pressure; Female; Humans; Hypertension; Male; Renin | 2023 |
Detecting primary aldosteronism in Australian primary care: a prospective study.
Topics: Adult; Aldosterone; Australia; Humans; Hyperaldosteronism; Hypertension; Primary Health Care; Prospe | 2022 |
Renal artery occlusive disease, renin-angiotensin-aldosterone, inflammation, and refractory arterial hypertension, a half-century's perspective.
Topics: Aldosterone; Angiotensin II; Angiotensins; Blood Pressure; Humans; Hypertension; Inflammation; Renal | 2022 |
Circulating renin-angiotensin-aldosterone system activity in cats with systemic hypertension or cardiomyopathy.
Topics: Aldosterone; Amlodipine; Animals; Biomarkers; Cardiomyopathies; Cat Diseases; Cats; Furosemide; Hype | 2022 |
Plasma aldosterone to renin ratio for the detection of primary aldosteronism in patients with drug-resistant hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 2022 |
Impact of renin-angiotensin-aldosterone-system inhibitor drugs on mortality in patients with atrial fibrillation and hypertension.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensin | 2022 |
Machine learning-based models for predicting clinical outcomes after surgery in unilateral primary aldosteronism.
Topics: Adrenalectomy; Aldosterone; Antihypertensive Agents; Cross-Sectional Studies; Humans; Hyperaldostero | 2022 |
Case Report: Primary Aldosteronism Due to Bilateral Aldosterone-Producing Micronodules With HISTALDO Classical and Contralateral Non-Classical Pathology.
Topics: Adenoma; Adrenocortical Adenoma; Aldosterone; Cytochrome P-450 CYP11B2; Female; G Protein-Coupled In | 2022 |
Early Renin Recovery After Adrenalectomy in Aldosterone-Producing Adenomas: A Prospective Study.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adrenocorticotropic Hormone | 2022 |
A pilot study to evaluate the erythrocyte glycocalyx sensitivity to sodium as a marker for cellular salt sensitivity in hypertension.
Topics: Aldosterone; Blood Pressure; Erythrocytes; Essential Hypertension; Female; Glycocalyx; Humans; Hyper | 2023 |
Japan Endocrine Society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021.
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Japan; Mineralocorticoid Recep | 2022 |
Primary aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2022 |
Covid-19 associated reduction in hypertension-related diagnostic and therapeutic procedures in Excellence Centers of the European Society of Hypertension.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Catecho | 2022 |
The use of renin angiotensin aldosterone system inhibitors may be associated with decreased mortality after cancer surgery.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hyper | 2022 |
Creation of a quick and sensitive fluorescent immunosensor for detecting the mineralocorticoid steroid hormone aldosterone.
Topics: Aldosterone; Biosensing Techniques; Humans; Hypertension; Immunoassay; Mineralocorticoids | 2022 |
Primary Aldosteronism More Prevalent in Patients With Cardioembolic Stroke and Atrial Fibrillation.
Topics: Aldosterone; Atrial Fibrillation; Embolic Stroke; Humans; Hyperaldosteronism; Hypertension; Renin; S | 2022 |
Higher plasma renin activity is associated with increased kidney damage risk in patients with hypertension and glucose metabolic disorders.
Topics: Aldosterone; Glucose Metabolism Disorders; Humans; Hypertension; Kidney; Proteinuria; Renal Insuffic | 2022 |
Association of Renin-Angiotensin-Aldosterone Inhibitors with COVID-19 Infection and Disease Severity among Individuals with Hypertension.
Topics: Aldosterone; Angiotensins; Antihypertensive Agents; COVID-19 Drug Treatment; Humans; Hypertension; M | 2022 |
Divergent Characteristics of T-Cell Receptor Repertoire Between Essential Hypertension and Aldosterone-Producing Adenoma.
Topics: Adenoma; Aldosterone; Essential Hypertension; Humans; Hypertension; Receptors, Antigen, T-Cell; Reni | 2022 |
Hypertension Resolution after Laparoscopic Adrenal Tumor Resection in Patients of Adrenal Incidentaloma with Normal Hormone Levels.
Topics: Adrenal Gland Neoplasms; Aldosterone; Female; Humans; Hypertension; Laparoscopy; Male; Retrospective | 2023 |
Clinical, biochemical, and miRNA profile of subjects with positive screening of primary aldosteronism and nonclassic apparent mineralocorticoid excess.
Topics: Aldosterone; Cortisone; Cross-Sectional Studies; Humans; Hyperaldosteronism; Hypertension; Lipocalin | 2022 |
Prevalence and clinical characteristics of primary aldosteronism in a tertiary-care center in Korea.
Topics: Adult; Aldosterone; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hyperaldosteronism; Hyper | 2022 |
'I can't understand why others don't screen more': a qualitative study exploring why Australian general practitioners screen for primary aldosteronism.
Topics: Aldosterone; Antihypertensive Agents; Australia; Female; General Practitioners; Humans; Hyperaldoste | 2022 |
Liddle syndrome misdiagnosed as primary aldosteronism is caused by inaccurate aldosterone-rennin detection while a novel
Topics: Adult; Aldosterone; Chymosin; Diagnostic Errors; Epithelial Sodium Channels; Female; Humans; Hyperal | 2022 |
Ambulatory fludrocortisone suppression test in the diagnosis of primary aldosteronism: Safety, accuracy and cost-effectiveness.
Topics: Aldosterone; Cost-Benefit Analysis; Fludrocortisone; Humans; Hyperaldosteronism; Hypertension; Renin | 2022 |
Association of cardiovascular disease risk and changes in renin levels by mineralocorticoid receptor antagonists in patients with primary aldosteronism.
Topics: Aldosterone; Cardiovascular Diseases; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Re | 2022 |
Comparison of Echocardiographic Changes Between Surgery and Medication Treatment in Patients With Primary Aldosteronism.
Topics: Aldosterone; Echocardiography; Humans; Hyperaldosteronism; Hypertension; Hypertrophy, Left Ventricul | 2022 |
Reliability Analysis of a Functional Diagnostic Test for Primary Hyperaldosteronism Based on Data Analysis.
Topics: Aldosterone; Data Analysis; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hypertension; Ren | 2022 |
Hunting for protective drugs at the break of a pandemic: Causal inference from hospital data.
Topics: Aldosterone; COVID-19 Drug Treatment; Hospitals; Humans; Hypertension; Pandemics; Protective Agents; | 2022 |
Primary Aldosteronism Screening Rates Differ with Sex, Race, and Comorbidities.
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Mass Screen | 2022 |
Upregulation of Mineralocorticoid Receptor Contributes to Development of Salt-Sensitive Hypertension after Ischemia-Reperfusion Injury in Rats.
Topics: Aldosterone; Animals; Blood Pressure; Hypertension; Kidney; Rats; Receptors, Mineralocorticoid; Repe | 2022 |
The metabolic phenotype of patients with primary aldosteronism: impact of subtype and sex - a multicenter-study of 3566 Caucasian and Asian subjects.
Topics: Adenoma; Aldosterone; Diabetes Mellitus, Type 2; Female; Humans; Hydrocortisone; Hyperaldosteronism; | 2022 |
Relationship Between Risks for Obstructive Sleep Apnea, Resistant Hypertension, and Aldosterone Among African American Adults in the Jackson Heart Study.
Topics: Adult; Aldosterone; Black or African American; Cross-Sectional Studies; Humans; Hypertension; Longit | 2022 |
Chinese normotensive and essential hypertensive reference intervals for plasma aldosterone and renin activity by liquid chromatography-tandem mass spectrometry.
Topics: Aged; Aldosterone; Blood Pressure; China; Chromatography, Liquid; Humans; Hypertension; Renin; Tande | 2022 |
Clinical and biochemical predictors and predictive model of primary aldosteronism.
Topics: Adrenal Gland Neoplasms; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Middle Aged; | 2022 |
Pseudohypoaldosteronism associated with hypertrophic cardiomyopathy, hypertension and thrombocytosis due to mutation in the ELAC2 gene: a case report.
Topics: Aldosterone; Cardiomyopathy, Hypertrophic; Child; Humans; Hypertension; Mutation; Neoplasm Proteins; | 2022 |
Effect of Angiotensin receptor blockade on Plasma Osmolality and Neurohumoral Responses to High Environmental Temperature in Rats Fed a High Salt Diet.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit | 2021 |
Anti-Hypertensive Effects of Anthocyanins from Hibiscus sabdarifa Calyx on the Renin-Angiotensin-Aldoslestrone System in Wistar Rats.
Topics: Aldosterone; Animals; Anthocyanins; Antihypertensive Agents; Blood Pressure; Captopril; Hibiscus; Hy | 2022 |
Variability of aldosterone, renin and the aldosterone-to-renin ratio in hypertensive patients without primary aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Reproducibility of Results | 2022 |
Two cases of aldosterone and cortisol producing adenoma with different histopathological features: A case report.
Topics: Adenoma; Aldosterone; Cytochrome P-450 CYP11B2; Humans; Hydrocortisone; Hyperaldosteronism; Hyperten | 2022 |
Aldosterone breakthrough as a clue to the physiological importance of paracrine regulation of aldosterone secretion.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Humans; Hypertension | 2022 |
A case of malignant nephrosclerosis occurring with serum renin in the normal range.
Topics: Adult; Aldosterone; Humans; Hypertension; Male; Nephrosclerosis; Reference Values; Renin | 2023 |
Genetic screening of hypertensive patients with aldosterone hypersecretion under conditions of stress.
Topics: Aldosterone; Genetic Testing; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor A | 2022 |
Primary aldosteronism caused by a pI157S somatic
Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Child; Female; G | 2022 |
Prevalence of Primary Aldosteronism in Newly Diagnosed Hypertensive Patients in Primary Care.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Prevalence; Primary Health Care; | 2022 |
Impact of dedicated multidisciplinary service on patient selection and outcomes for surgical treatment of primary aldosteronism.
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Patient Selection; Retrospecti | 2022 |
Circulating Plasma Concentrations of ACE2 in Primary Aldosteronism and Cardiovascular Outcomes.
Topics: Adrenalectomy; Aldosterone; Angiotensin-Converting Enzyme 2; Cardiovascular Diseases; Essential Hype | 2022 |
Associated factors and effects of comorbid atrial fibrillation in hypertensive patients due to primary aldosteronism.
Topics: Adult; Aldosterone; Atrial Fibrillation; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; M | 2023 |
Aldosterone, Renin, and Aldosterone-to-Renin Ratio Variability in Screening for Primary Aldosteronism.
Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin; Retrospecti | 2022 |
Primary aldosteronism presenting as embolic myocardial infarction.
Topics: Adrenal Glands; Aldosterone; Arrhythmias, Cardiac; Embolism; Female; Humans; Hyperaldosteronism; Hyp | 2022 |
Green tea could improve elderly hypertension by modulating arterial stiffness, the activity of the renin/angiotensin/aldosterone axis, and the sodium-potassium pumps in old male rats.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Hypertension; Lipids; M | 2022 |
Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia.
Topics: Aldosterone; Angiotensins; Animals; Female; Galectins; Humans; Hypertension; Mice; NADP; NADPH Oxida | 2022 |
Screening for primary aldosteronism: The "PA" Shiny app.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Mobile Applications; Renin | 2022 |
Inconsistencies in laboratory investigations of hypertension in a young woman taking ethinylestradiol/drospirenone association.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Renin | 2023 |
Unilateral Adrenalectomy for Primary Aldosteronism Due to Bilateral Adrenal Disease Can Result in Resolution of Hypokalemia and Amelioration of Hypertension.
Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperald | 2023 |
Catheter-based adrenal ablation: an alternative therapy for patients with aldosterone-producing adenoma.
Topics: Adenoma; Adrenalectomy; Aldosterone; Catheters; Humans; Hyperaldosteronism; Hypertension; Retrospect | 2023 |
Importance of dietary salt restriction for patients with primary aldosteronism during treatment with mineralocorticoid receptor antagonists: The potential importance of post-treatment plasma renin levels.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor An | 2023 |
Higher plasma aldosterone is associated with increased risk of cardiovascular events in hypertensive patients with suspected OSA: UROSAH data.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Cardiovascular Diseases; Humans; Hyperaldos | 2022 |
[New clinical opportunities for mineralocorticoid receptor antagonists: focus on antifibrotic effects].
Topics: Aldosterone; COVID-19 Drug Treatment; Eplerenone; Humans; Hypertension; Mineralocorticoid Receptor A | 2021 |
[Primary hyperaldosteronism: indications for screening].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Renin | 2022 |
Mutagenesis of the cleavage site of (pro)renin receptor abrogates aldosterone-salt-induced hypertension and renal injury in mice.
Topics: Aldosterone; Angiotensin II; Animals; Hypertension; Kidney; Mice; Mineralocorticoids; Mutagenesis; P | 2023 |
Salt-Losing Syndrome in a Girl with Type I and II Pseudohypoaldosteronism.
Topics: Acidosis; Aldosterone; Female; Humans; Hyperkalemia; Hypertension; Hyponatremia; Infant; Pseudohypoa | 2022 |
Lysine-specific demethylase 1 deficiency modifies aldosterone synthesis in a sex-specific manner.
Topics: Aldosterone; Animals; Blood Pressure; Female; Hypertension; Lysine; Male; Mice; Zona Glomerulosa | 2023 |
Implication of MR Activity in Posttreatment Arterial Stiffness Reversal in Patients With Primary Aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Pulse Wave Analysis; Renin; Vascular Stiffnes | 2023 |
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype | 2023 |
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype | 2023 |
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype | 2023 |
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype | 2023 |
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype | 2023 |
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype | 2023 |
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype | 2023 |
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype | 2023 |
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype | 2023 |
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin | 2023 |
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin | 2023 |
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin | 2023 |
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin | 2023 |
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin | 2023 |
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin | 2023 |
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin | 2023 |
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin | 2023 |
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin | 2023 |
An explorative epigenome-wide association study of plasma renin and aldosterone concentration in a Ghanaian population: the RODAM study.
Topics: Aldosterone; DNA Methylation; Epigenesis, Genetic; Epigenome; Ghana; Humans; Hypertension; Nerve Tis | 2022 |
An explorative epigenome-wide association study of plasma renin and aldosterone concentration in a Ghanaian population: the RODAM study.
Topics: Aldosterone; DNA Methylation; Epigenesis, Genetic; Epigenome; Ghana; Humans; Hypertension; Nerve Tis | 2022 |
An explorative epigenome-wide association study of plasma renin and aldosterone concentration in a Ghanaian population: the RODAM study.
Topics: Aldosterone; DNA Methylation; Epigenesis, Genetic; Epigenome; Ghana; Humans; Hypertension; Nerve Tis | 2022 |
An explorative epigenome-wide association study of plasma renin and aldosterone concentration in a Ghanaian population: the RODAM study.
Topics: Aldosterone; DNA Methylation; Epigenesis, Genetic; Epigenome; Ghana; Humans; Hypertension; Nerve Tis | 2022 |
Primary aldosteronism is a clinical issue that should not be underestimated anymore.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2023 |
Primary aldosteronism is a clinical issue that should not be underestimated anymore.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2023 |
Primary aldosteronism is a clinical issue that should not be underestimated anymore.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2023 |
Primary aldosteronism is a clinical issue that should not be underestimated anymore.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2023 |
A case report of a young boy with low renin and high aldosterone levels induced by Liddle syndrome who was previously misdiagnosed with primary aldosteronism.
Topics: Adolescent; Aldosterone; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; L | 2023 |
A case report of a young boy with low renin and high aldosterone levels induced by Liddle syndrome who was previously misdiagnosed with primary aldosteronism.
Topics: Adolescent; Aldosterone; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; L | 2023 |
A case report of a young boy with low renin and high aldosterone levels induced by Liddle syndrome who was previously misdiagnosed with primary aldosteronism.
Topics: Adolescent; Aldosterone; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; L | 2023 |
A case report of a young boy with low renin and high aldosterone levels induced by Liddle syndrome who was previously misdiagnosed with primary aldosteronism.
Topics: Adolescent; Aldosterone; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; L | 2023 |
The promise of selective aldosterone synthase inhibition for the management of resistant hypertension.
Topics: Aldosterone; Blood Pressure; Cytochrome P-450 CYP11B2; Humans; Hypertension | 2023 |
Behavior of the renal kallikrein in spontaneously hypertensive rats: Influence of sexual hormones and aldosterone-sensitive distal nephron ion channels.
Topics: Aldosterone; Animals; Epithelial Sodium Channels; Female; Hypertension; Ion Channels; Kallikreins; K | 2023 |
Fatty acids as a direct regulator of aldosterone hypersecretion.
Topics: Aldosterone; Cytochrome P-450 CYP11B2; Fatty Acids; Humans; Hyperaldosteronism; Hypertension; Palmit | 2023 |
Effect of Metabolic Adaptation by Voluntary Running Wheel Activity and Aldosterone Inhibition on Renal Function in Female Spontaneously Hypertensive Rats.
Topics: Aldosterone; Animals; Body Weight; Female; Hypertension; Kidney; Motor Activity; Proprotein Converta | 2022 |
The selective aldosterone synthase inhibitor Baxdrostat significantly lowers blood pressure in patients with resistant hypertension.
Topics: Aldosterone; Blood Pressure; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Humans; Hypertension; Mine | 2022 |
Serum aldosterone effect on left ventricular structure and diastolic function in essential hypertension.
Topics: Aldosterone; Diastole; Echocardiography; Essential Hypertension; Female; Humans; Hypertension; Hyper | 2023 |
Effect of Oral Contraception on Screening Tests for Primary Aldosteronism: A 10-Year Longitudinal Study.
Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Longitudinal Studi | 2023 |
Advances in Medical Treatment of Primary Aldosteronism.
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Ant | 2023 |
Diabetes mellitus is associated with more adverse non-hemodynamic left ventricular remodeling and less recovery in patients with primary aldosteronism.
Topics: Aldosterone; Diabetes Mellitus; Echocardiography; Humans; Hyperaldosteronism; Hypertension; Hypertro | 2023 |
New CT Scan Distinguishes Primary Aldosteronism Subtypes.
Topics: Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Tomography, X-Ray Computed | 2023 |
Acute psychotic episode inaugurating a primary hyperaldosteronism: a case report.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypok | 2022 |
The DOCA-Salt Model of Hypertension for Studies of Cerebrovascular Function, Stroke, and Brain Health.
Topics: Acetates; Aldosterone; Brain; Desoxycorticosterone Acetate; Humans; Hypertension; Renin-Angiotensin | 2023 |
The effect of age, sex and BMI on the aldosterone-to-renin ratio in essential hypertensive individuals.
Topics: Aldosterone; Body Mass Index; Female; Humans; Hyperaldosteronism; Hypertension; Male; Renin | 2023 |
Decreasing the Effects of Aldosterone in Resistant Hypertension - A Success Story.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension | 2023 |
Aldosterone and Treatment-Resistant Hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Monit | 2023 |
Malignant Hypertension and Bilateral Primary Aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Mineralocorticoid Re | 2023 |
Coexistence of Pheochromocytoma and Primary Aldosteronism due to Multiple Aldosterone-producing Micronodules in the Ipsilateral Adrenal Gland.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Female; Humans; Hyperaldosteron | 2023 |
International multicenter survey on screening and confirmatory testing in primary aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Surveys and Questionnaires | 2023 |
Association of objective and subjective parameters of obstructive sleep apnea with plasma aldosterone concentration in 2,066 hypertensive and 25,368 general population.
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Male; Sleep; Sleep Apnea, Obstructive | 2022 |
Aldosterone Synthase Inhibitors and the Treatment of Essential Hypertension.
Topics: Aldosterone; Cytochrome P-450 CYP11B2; Essential Hypertension; Humans; Hyperaldosteronism; Hypertens | 2023 |
Effect of the interaction between the visceral-to-subcutaneous fat ratio and aldosterone on cardiac function in patients with primary aldosteronism.
Topics: Aldosterone; Cardiovascular Diseases; Humans; Hyperaldosteronism; Hypertension; Intra-Abdominal Fat; | 2023 |
The renin-angiotensin-aldosterone system: a new look at an old system.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin; Renin-Angiotensin System | 2023 |
Association of Aldosterone with Mortality in the General Population.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Humans; Hypertension; Inflammatio | 2023 |
Impact of a change to a novel chemiluminescent immunoassay for measuring plasma aldosterone on the diagnosis of primary aldosteronism.
Topics: Aldosterone; Captopril; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Immunoassay; Renin; R | 2023 |
Pitfalls in the diagnosis and treatment of a hypertensive patient with unilateral primary aldosteronism and contralateral pheochromocytoma: a case report.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Female; Humans; Hyperaldosteron | 2023 |
RAS-challenge as a first-look test for detection of primary aldosteronism in patients with treatment-resistant hypertension.
Topics: Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin | 2023 |
ER ribosomal-binding protein 1 regulates blood pressure and potassium homeostasis by modulating intracellular renin trafficking.
Topics: Aldosterone; Aluminum Oxide; Animals; Blood Pressure; Carrier Proteins; Genome-Wide Association Stud | 2023 |
Renin, Aldosterone, and Cortisol in Pregnancy-Induced Hypertension.
Topics: Aldosterone; Female; Humans; Hydrocortisone; Hypertension; Hypertension, Pregnancy-Induced; Potassiu | 2023 |
Aldosterone breakthrough from a pharmacological perspective.
Topics: Aldosterone; Humans; Hypertension; Renin; Renin-Angiotensin System | 2023 |
A hyperaldosteronism subtypes predictive model using ensemble learning.
Topics: Adenoma; Aldosterone; Cross-Sectional Studies; Humans; Hyperaldosteronism; Hypertension; Potassium; | 2023 |
Smooth Muscle Mineralocorticoid Receptor Promotes Hypertension After Preeclampsia.
Topics: Aldosterone; Animals; Female; Humans; Hypertension; Mice; Muscle, Smooth; Pre-Eclampsia; Pregnancy; | 2023 |
[Noninvasive stratification of primary aldosteronism: a glimpse of latest updates].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2023 |
Screening for Primary Aldosteronism Among Hypertensive Adults with Obstructive Sleep Apnea: A Retrospective Population-Based Study.
Topics: Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Ontario; Renin; Retrospec | 2023 |
Visceral fat: a bad companion for mineralocorticoid receptor overactivation.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Intra-Abdominal Fat; Receptors, Mineralocorti | 2023 |
Usefulness of Alternative Therapy with Hydrocortisone in the Postoperative Management of Severe Primary Aldosteronism.
Topics: Adrenalectomy; Aldosterone; Humans; Hydrocortisone; Hyperaldosteronism; Hyperkalemia; Hypertension; | 2023 |
Topics: Aldosterone; Humans; Hypertension | 2023 |
An Abbreviated History of Aldosterone Metabolism, Current and Future Challenges.
Topics: Aldosterone; Animals; Glucuronides; Glucuronosyltransferase; Hyperaldosteronism; Hypertension | 2023 |
Early Implementation of Aldosterone-Targeted Therapy in Patients With Hypertension.
Topics: Aldosterone; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Receptors, Mineralocortic | 2023 |
Blood Levels of Angiotensinogen and Hypertension in the Multi-Ethnic Study of Atherosclerosis (MESA).
Topics: Adult; Aldosterone; Angiotensinogen; Atherosclerosis; Blood Pressure; Female; Humans; Hypertension; | 2023 |
Efficacy of Antihypertensive Drugs of Different Classes After Renal Denervation in Spontaneously Hypertensive Rats.
Topics: Aldosterone; Amlodipine; Animals; Antihypertensive Agents; Bisoprolol; Blood Pressure; Cardiomyopath | 2023 |
Reference intervals for LC-MS /MS measurements of plasma renin activity, aldosterone, angiotensin II, and 24-hour urinary aldosterone in Northern Chinese Han population.
Topics: Aldosterone; Angiotensin II; Chromatography, Liquid; East Asian People; Healthy Volunteers; Humans; | 2023 |
Renal Artery Stenosis Complicated with Primary Aldosteronism.
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Renal Artery Obstruction; Reni | 2023 |
Decoding Hypertension Through Primary Aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2023 |
Using Renin Activity to Guide Mineralocorticoid Receptor Antagonist Therapy in Patients with Low Renin and Hypertension.
Topics: Adult; Aldosterone; Cohort Studies; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Rece | 2023 |
Hypertension in Primary Aldosteronism Is Initiated by Salt-Induced Increases in Vascular Resistance With Reductions in Cardiac Output.
Topics: Aldosterone; Animals; Blood Pressure; Cardiac Output; Hemodynamics; Hyperaldosteronism; Hypertension | 2023 |
Primary Aldosteronism and Drug Resistant Hypertension: A "Chicken-Egg" Story.
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Risk Factors | 2023 |
Evidence and Uncertainties Surrounding Renin-Guided Medical Therapy for Primary Aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Miner | 2023 |
[Adrenalectomy for primary hyperaldosteronism : retrospective review of 57 patients in CHU of Liege].
Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Retros | 2023 |
Clues to suspect aldosterone breakthrough in the real world.
Topics: Aldosterone; Humans; Hypertension; Potassium; Renin | 2023 |
Screening for primary aldosteronism in primary care.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Primary Health Care; Renin | 2023 |
Unique Case of Cardiomyopathy Secondary to Adrenal Adenoma (Primary-Aldosteronism).
Topics: Adenoma; Adrenocortical Adenoma; Aldosterone; Cardiomyopathies; Female; Humans; Hyperaldosteronism; | 2023 |
Association Between Life's Simple 7 and Biomarkers of Cardiovascular Disease: Aldosterone, Interleukin-6, C-Reactive Protein.
Topics: Adolescent; Adult; Aged; Aldosterone; Biomarkers; Blood Pressure; C-Reactive Protein; Cardiovascular | 2023 |
The Prevalence of Primary Aldosteronism in Screening Populations: Is Hypokalaemia Important?
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Mass Screening; Prevalence | 2023 |
Duplicated adrenal veins in primary aldosteronism misdiagnosed with ectopic aldosteronoma due to apparent bilateral aldosterone suppression.
Topics: Adrenal Glands; Aldosterone; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension; Hypokalemi | 2023 |
Mineralocorticoid receptor blockade protects the kidneys but does not affect inverted blood pressure rhythm in hypertensive transgenic (mRen-2)27 rats.
Topics: Albuminuria; Aldosterone; Animals; Animals, Genetically Modified; Blood Pressure; Hypertension; Kidn | 2023 |
Adrenocorticotropic hormone application lowered aldosterone/cortisol value on dominant side without superior surgical outcomes during adrenal venous sampling.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Humans; Hydrocortisone; Hyperaldosteronism | 2023 |
Predictive performance of aldosterone-to-renin ratio in the diagnosis of primary aldosteronism in patients with resistant hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Renin; Reproducibility of Result | 2023 |
High plasma aldosterone concentration is associated with worse 24-h ambulatory blood pressure profile in patients with primary aldosteronism.
Topics: Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Car | 2023 |
Biochemical Evaluation by Confirmatory Tests after Unilateral Adrenalectomy for Primary Aldosteronism.
Topics: Adrenalectomy; Aldosterone; Captopril; Furosemide; Humans; Hyperaldosteronism; Hypertension; Renin; | 2023 |
Impact of gut microbiome on the renin-aldosterone system: Shika-machi Super Preventive Health Examination results.
Topics: Aldosterone; Animals; Gastrointestinal Microbiome; Humans; Hypertension; Renin; Renin-Angiotensin Sy | 2023 |
Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Cell Adhesion Molecule-1; Cytochrome | 2023 |
Aldosterone Biosynthesis Is Potently Stimulated by Perfluoroalkyl Acids: A Link between Common Environmental Pollutants and Arterial Hypertension.
Topics: Adrenal Cortex Neoplasms; Aldosterone; Alkanesulfonic Acids; Cytochrome P-450 CYP11B2; Environmental | 2023 |
Case series: Primary aldosteronism diagnosed despite normal screening investigations: A report of three cases.
Topics: Adenoma; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Positron Emi | 2023 |
NGAL is a Novel Target in Hypertension by Modulating the NCC-Mediated Renal Na Balance.
Topics: Aldosterone; Animals; Hypertension; Kidney; Lipocalin-2; Mice; Mice, Knockout; Sodium; Solute Carrie | 2023 |
Association of urinary liver-type fatty acid-binding protein with outcomes after adrenalectomy for unilateral primary aldosteronism.
Topics: Adrenalectomy; Adult; Aldosterone; Creatinine; Female; Humans; Hyperaldosteronism; Hypertension; Liv | 2023 |
Importance of plasma aldosterone concentrations as a clinical indicator of nocturnal hypertension in primary aldosteronism.
Topics: Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hyperaldosteronism; Hype | 2023 |
Prolonged postoperative hypoaldosteronism related to hyperkalemia in patients with aldosterone-producing adenoma.
Topics: Adenoma; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hyperkalemi | 2023 |
Non-suppression of renin by renal cysts in a subset of patients with primary aldosteronism-a prospective observational single center study.
Topics: Adult; Aged; Aldosterone; Cysts; Female; Humans; Hyperaldosteronism; Hypertension; Kidney Diseases, | 2023 |
Using plasma aldosterone concentrations at 1 h of saline infusion test for the diagnosis of primary aldosteronism.
Topics: Aldosterone; Cross-Sectional Studies; Humans; Hyperaldosteronism; Hypertension; Infusions, Intraveno | 2023 |
The Impact of Obesity on the Resolution of Hypertension Following Adrenalectomy for Primary Hyperaldosteronism.
Topics: Adrenalectomy; Aldosterone; Antihypertensive Agents; Humans; Hyperaldosteronism; Hypertension; Hypok | 2023 |
Novel mechanisms of salt-sensitive hypertension.
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Receptors | 2023 |
Concurrent disorders of cats with diabetes mellitus and arterial systolic hypertension.
Topics: Aldosterone; Amlodipine; Animals; Antihypertensive Agents; Cat Diseases; Cats; Diabetes Mellitus; Hy | 2023 |
Improvement of hypertension control and left-ventricular function after cure of primary hyperparathyroidism.
Topics: Adult; Aged; Aldosterone; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hypercalcemia; Hype | 2023 |
Could we be missing something when calculating the aldosterone-to-renin ratio?
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 2023 |
Reply to 'Could we be missing something when calculating the aldosterone-to-renin ratio?'
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 2023 |
Progress in Primary Aldosteronism 7: No better time to meet!
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2023 |
Aldosterone and renin concentrations and blood pressure in young Indigenous and non-Indigenous adults in the Northern Territory: a cross-sectional study.
Topics: Adult; Aldosterone; Blood Pressure; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hyp | 2023 |
Simple standing test without furosemide is useful in the diagnosis of primary aldosteronism.
Topics: Aldosterone; Captopril; Furosemide; Humans; Hyperaldosteronism; Hypertension; Retrospective Studies | 2023 |
Aldosterone Antagonism Is More Effective at Reducing Blood Pressure and Excessive Renal ENaC Activity in AngII-Infused Female Rats Than in Males.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Diuretics; Female; Hypertension; Hypo | 2023 |
Association and progression of multi-morbidity with Chronic Kidney Disease stage 3a secondary to Type 2 Diabetes Mellitus, grouped by albuminuria status in the multi-ethnic population of Northwest London: A real-world study.
Topics: Albuminuria; Aldosterone; Diabetes Mellitus, Type 2; Heart Failure; Humans; Hypertension; London; Mi | 2023 |
Unique Gene Expression Signature in Periadrenal Adipose Tissue Identifies a High Blood Pressure Group in Patients With Cushing Syndrome.
Topics: Adipose Tissue; Aldosterone; Angiotensins; Blood Pressure; Cushing Syndrome; Humans; Hydrocortisone; | 2023 |
Vasoactive mediators of hypertension in obesity.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure; Cross-Sectional Studies; Humans | 2023 |
Associations Between Aldosterone-Renin-Ratio and Bone Parameters Derived from Peripheral Quantitative Computed Tomography and Impact Microindentation in Men.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Male; Renin; Renin-Angiotensin System; Tomogr | 2023 |
Aldosterone Synthase Inhibition With Lorundrostat for Uncontrolled Hypertension: The Target-HTN Randomized Clinical Trial.
Topics: Adult; Aldosterone; Blood Pressure; Cytochrome P-450 CYP11B2; Humans; Hyperaldosteronism; Hypertensi | 2023 |
A New Dawn for Aldosterone as a Therapeutic Target in Hypertension.
Topics: Aldosterone; Humans; Hypertension; Molecular Targeted Therapy | 2023 |
Primary Aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Spironolactone | 2023 |
Surgery based on computed tomography images might be feasible for primary aldosteronism patients with visible unilateral adenoma.
Topics: Adenoma; Adrenal Glands; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Middl | 2023 |
Skin NA+, K+ and water before and after surgical cure of human primary aldosteronism: Erratum.
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Water | 2023 |
Who and How Should We Screen for Primary Aldosteronism?
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Reni | 2023 |
Expression of functional mineralocorticoid receptor (MR) and G-protein coupled estrogen receptor (GPER) in human T lymphocytes.
Topics: Aldosterone; CD8-Positive T-Lymphocytes; GTP-Binding Proteins; Humans; Hypertension; Receptors, Estr | 2023 |
Topics: Aldosterone; Blood Pressure; Calcium Channels, L-Type; Diet, Sodium-Restricted; Female; Humans; Hype | 2023 |
Central diastolic blood pressure, plasma aldosterone and uric acid are associated with microalbuminuria in essential hypertension: a case-control study.
Topics: Albuminuria; Aldosterone; Blood Pressure; Case-Control Studies; Essential Hypertension; Humans; Hype | 2023 |
Unilateral adrenalectomy for a drug-resistant bilateral primary aldosteronism with heart failure: pathophysiology and surgical indication.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Antihypertensive Agents; Bisoprolol; Eplerenone; Heart F | 2023 |
Increasing rates of referrals for investigation of primary aldosteronism at a tertiary centre.
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Ant | 2023 |
[Is there an alternative treatment option for patients with primary aldosteronism?]
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2023 |
Higher plasma aldosterone concentrations in patients with aortic diseases and hypertension: a retrospective observational study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Aortic Diseases; Blood Pressure; Female; Hu | 2023 |
Liddle syndrome presenting with normal aldosterone levels: A case report.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Liddle Syndrome; Renin | 2023 |
Bilateral co-secretory lesions presenting with coexisting Cushing syndrome and primary aldosteronism: a case report.
Topics: Adrenocortical Adenoma; Adrenocorticotropic Hormone; Aldosterone; Cushing Syndrome; Female; Humans; | 2023 |
Historical changes and between-facility differences in adrenal venous sampling for primary aldosteronism in Japan.
Topics: Adrenal Glands; Aldosterone; Blood Specimen Collection; Endocrinology; Female; Hematologic Tests; Hu | 2020 |
Quantitation and clinical evaluation of plasma aldosterone by ultra-performance liquid chromatography-mass spectrometry.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Chromatography, High Pressure Liquid; Enzym | 2020 |
Rare cause of severe hypertension in an adolescent boy presenting with short stature: Answers.
Topics: Adolescent; Aldosterone; Body Height; Cullin Proteins; Developmental Disabilities; Diagnosis, Differ | 2020 |
A rare cause of hypertension in childhood: Questions.
Topics: Aldosterone; Alkalosis; Bartter Syndrome; Child; Child, Preschool; Consanguinity; Female; Humans; Hy | 2020 |
A rare cause of hypertension in childhood: Answers.
Topics: Aldosterone; Alkalosis; Bartter Syndrome; Child; Child, Preschool; Consanguinity; Cortisone; Diagnos | 2020 |
Interpreting stimulated plasma renin and aldosterone to select physiologically individualized therapy for resistant hypertension: importance of the class of stimulating drugs.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Co | 2019 |
ANO4 (Anoctamin 4) Is a Novel Marker of Zona Glomerulosa That Regulates Stimulated Aldosterone Secretion.
Topics: Adrenal Cortex; Aldosterone; Analysis of Variance; Anoctamins; Cell Communication; Cell Proliferatio | 2019 |
Adherence to consensus guidelines for screening of primary aldosteronism in an urban healthcare system.
Topics: Aged; Aldosterone; Animals; Consensus; Female; Guideline Adherence; Humans; Hyperaldosteronism; Hype | 2020 |
A Young Female With Refractory Hypertension.
Topics: Adult; Aldosterone; Antihypertensive Agents; Drug Resistance; Drug Therapy, Combination; Female; Hum | 2020 |
Seated saline infusion test in predicting subtype diagnosis of primary aldosteronism.
Topics: Adrenocortical Adenoma; Adult; Aldosterone; Cosyntropin; Female; Humans; Hyperaldosteronism; Hyperte | 2019 |
The hypertensive child.
Topics: Abdominal Pain; Adrenocorticotropic Hormone; Aldosterone; Amlodipine; Antihypertensive Agents; Catec | 2019 |
Simplifying the Diagnosis of Primary Aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium | 2020 |
Mild primary aldosteronism (PA) followed by overt PA are possibly the most common forms of low renin hypertension: a single-center retrospective study.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Retrospective Studies | 2020 |
Construction of a predictive scoring system as a guide to screening and confirmation of the diagnosis of primary aldosteronism.
Topics: Adolescent; Adult; Aged; Aldosterone; Cross-Sectional Studies; Diagnostic Techniques, Endocrine; Fem | 2020 |
Unilateral primary aldosteronism as an independent risk factor for vertebral fracture.
Topics: Adult; Aged; Aldosterone; Case-Control Studies; Cross-Sectional Studies; Female; Humans; Hyperaldost | 2020 |
[Stress the standardized diagnosis and management of primary aldosteronism].
Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hyperkalemia; Hypertension; Renin | 2020 |
Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals.
Topics: Aldosterone; Animals; Antifungal Agents; Azoles; Cricetinae; Disease Models, Animal; Drug Monitoring | 2020 |
NATURE OF CORRELATIONS AND DEPENDENCE OF PLASMA CONCENTRATIONS OF GALECTIN-3 AND ALDOSTERONE ON DIFFERENT CLINICAL CHARACTERISTICS IN MALE AND FEMALE PATIENTS WITH ARTERIAL HYPERTENSION.
Topics: Aldosterone; Female; Galectin 3; Humans; Hypertension; Male; Middle Aged; Obesity; Risk Factors | 2019 |
Two Mineralocorticoid Receptor-Mediated Mechanisms of Pendrin Activation in Distal Nephrons.
Topics: Aldosterone; Animals; Disease Models, Animal; Hypertension; Mice; Mice, Knockout; Nephrons; Receptor | 2020 |
Pharmacodynamics and metabonomics study of Tianma Gouteng Decoction for treatment of spontaneously hypertensive rats with liver-yang hyperactivity syndrome.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; C-Reactive Protein; Drugs | 2020 |
Appropriate timing for a biochemical evaluation after adrenalectomy for unilateral aldosterone-producing adenoma.
Topics: Adenoma; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Retrospective Studies | 2020 |
The effect of vitamin D treatment on clinical and biochemical outcomes of primary aldosteronism.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Parathyroid Hormone; Renin; V | 2020 |
Aldosterone-to-renin ratio and blood pressure in young adults from the general population.
Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Female; Humans; Hypertension; Male; Morbidity; Popul | 2020 |
mTORC1 Deficiency Modifies Volume Homeostatic Responses to Dietary Sodium in a Sex-Specific Manner.
Topics: Aldosterone; Animals; Blood Pressure; Female; Homeostasis; Hypertension; Kidney; Male; Mechanistic T | 2020 |
Determining the Prevalence of Primary Aldosteronism in Patients With New-Onset Type 2 Diabetes and Hypertension.
Topics: Aldosterone; Biomarkers; China; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Hypera | 2020 |
Not All Hypertension Is a Lifelong Disease: A Teachable Moment.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Antihypertensive Agent | 2020 |
Differences in hypertension phenotypes between Africans and Europeans: role of environment.
Topics: Aldosterone; Black People; Blood Pressure; Echocardiography; Ethnicity; Europe; Female; Heart Ventri | 2020 |
The risk factors for hepatic steatosis in patients with primary aldosteronism.
Topics: Adult; Aldosterone; Blood Pressure; Fatty Liver; Female; Humans; Hyperaldosteronism; Hypertension; I | 2020 |
Aldosterone-induced hypertension is sex-dependent, mediated by T cells and sensitive to GPER activation.
Topics: Aldosterone; Animals; Antihypertensive Agents; Benzodioxoles; Blood Pressure; Cyclopentanes; Disease | 2021 |
Primary aldosteronism in young adults with acute stroke: Prevalence and clinical characteristics.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Middle Aged; Prevalence; Stroke; | 2020 |
Age- and sex-specific reference ranges are needed for the aldosterone/renin ratio.
Topics: Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Infant, Newb | 2020 |
Impact of mineralocorticoid receptor blockade with direct renin inhibition in angiotensin II-dependent hypertensive mice.
Topics: Aldosterone; Amides; Animals; Antihypertensive Agents; Drug Evaluation, Preclinical; Drug Therapy, C | 2020 |
Autonomous Aldosterone Production and Left Ventricular Hypertrophy.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypertrophy, Left Ventricular | 2020 |
Spironolactone mitigates, but does not reverse, the progression of renal fibrosis in a transgenic hypertensive rat.
Topics: Aldosterone; Animals; Blood Pressure; Disease Models, Animal; Fibrosis; Hypertension; Kidney Disease | 2020 |
Elevated Renin and Aldosterone Levels in a Young Woman With Hypertension.
Topics: Adult; Aldosterone; Androstenes; Antihypertensive Agents; Computed Tomography Angiography; Contracep | 2020 |
The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study.
Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2020 |
The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study.
Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2020 |
The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study.
Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2020 |
The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study.
Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2020 |
Oestrogen receptors and T cells determine how sex affects aldosterone-induced hypertension.
Topics: Aldosterone; Humans; Hypertension; Receptors, Estrogen; T-Lymphocytes | 2021 |
[Diagnostic Efficiency of Different Screening Indexes for Primary Aldosteronism].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Retrospective Studies | 2020 |
[The Value of Serum Potassium and Ratio of Sodium to Potassium after Saline Infusion Test in Differential Diagnosis of Primary Hyperaldosteronism].
Topics: Aldosterone; China; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Potassium; Re | 2020 |
[Diagnosis and Treatment of Primary Aldosteronism in West China Hospital of Sichuan University from 2009 to 2018].
Topics: Adrenal Gland Neoplasms; Aldosterone; China; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2020 |
Primary Aldosteronism: The Next Decade.
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Ramipril; Renin | 2020 |
Seizure and coma secondary to Conn's syndrome: a case report.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Coma; Humans; | 2020 |
Clinical outcomes of primary aldosteronism based on lateralization index and contralateral suppression index after adrenal venous sampling in real-world practice: a retrospective cohort study.
Topics: Adrenal Glands; Adult; Aged; Aged, 80 and over; Aldosterone; Blood Specimen Collection; Catheterizat | 2020 |
Interplay Between Statins, Cav1 (Caveolin-1), and Aldosterone.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Caveolin 1; Cholesterol; Correlation of Data; Dyslipide | 2020 |
Serum uromodulin is inversely associated with arterial hypertension and the vasoconstrictive prohormone CT-proET-1 in the population-based KORA F4 study.
Topics: Aged; Aldosterone; Endothelin-1; Female; Humans; Hypertension; Male; Peptide Fragments; Renin; Uromo | 2020 |
The dangers of herbal teas: hypertension and weakness caused by liquorice-induced apparent mineralocorticoid excess.
Topics: Aldosterone; Alkalosis; Female; Glycyrrhiza; Humans; Hypertension; Hypokalemia; Middle Aged; Mineral | 2020 |
The potential pathophysiological role of aldosterone and the mineralocorticoid receptor in anxiety and depression - Lessons from primary aldosteronism.
Topics: Aldosterone; Anxiety; Depression; Female; Humans; Hyperaldosteronism; Hypertension; Male; Receptors, | 2020 |
Primary aldosteronism: Involvement of sympathetic system in the persistence of hypertension after surgery.
Topics: Adenoma; Adrenalectomy; Aldosterone; Denervation; Humans; Hyperaldosteronism; Hypertension; Laparosc | 2020 |
Evaluation of Adrenal Vein Sampling Use and Outcomes in Patients With Primary Aldosteronism.
Topics: Adrenal Cortex Function Tests; Adrenal Glands; Adrenalectomy; Adult; Aged; Aged, 80 and over; Aldost | 2020 |
Association between renin-angiotensin-aldosterone system inhibitor treatment, neutrophil-lymphocyte ratio, D-Dimer and clinical severity of COVID-19 in hospitalized patients: a multicenter, observational study.
Topics: Adult; Aged; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors | 2021 |
Adrenal artery ablation for primary aldosteronism without apparent aldosteronoma: An efficacy and safety, proof-of-principle trial.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Arteries; Humans; Hyperaldosteronism; Hypertension; Pros | 2020 |
Adrenal artery ablation for primary aldosteronism without apparent aldosteronoma: An efficacy and safety, proof-of-principle trial.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Arteries; Humans; Hyperaldosteronism; Hypertension; Pros | 2020 |
Adrenal artery ablation for primary aldosteronism without apparent aldosteronoma: An efficacy and safety, proof-of-principle trial.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Arteries; Humans; Hyperaldosteronism; Hypertension; Pros | 2020 |
Adrenal artery ablation for primary aldosteronism without apparent aldosteronoma: An efficacy and safety, proof-of-principle trial.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Arteries; Humans; Hyperaldosteronism; Hypertension; Pros | 2020 |
Taiwan mini-frontier of primary aldosteronism: Updating detection and diagnosis.
Topics: Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Taiwan | 2021 |
The cytochrome 11B2 aldosterone synthase gene rs1799998 single nucleotide polymorphism determines elevated aldosterone, higher blood pressure, and reduced glomerular filtration, especially in diabetic female patients.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Case-Control Studies; Cytochrome P-450 CYP11B2; Diabetes M | 2020 |
Genetics, prevalence, screening and confirmation of primary aldosteronism: a position statement and consensus of the Working Group on Endocrine Hypertension of The European Society of Hypertension.
Topics: Aldosterone; Consensus; Humans; Hyperaldosteronism; Hypertension; Prevalence | 2020 |
Potassium losing, aldosterone producing adrenocortical carcinoma: a rare presentation.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adult; Aldosteron | 2020 |
Association of -344C/T polymorphism in the aldosterone synthase (CYP11B2) gene with cardiac and cerebrovascular events in Chinese patients with hypertension.
Topics: Adult; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Card | 2020 |
Primary Aldosteronism: New Insights Into its Detection and Cardiac Involvement.
Topics: Aldosterone; Extracellular Matrix; Humans; Hyperaldosteronism; Hypertension; Magnetic Resonance Spec | 2020 |
Serum ACE2, Angiotensin II, and Aldosterone Levels Are Unchanged in Patients With COVID-19.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibito | 2021 |
Clinical characteristics of primary aldosteronism in newly diagnosed diabetes mellitus with hypertensive patients.
Topics: Aldosterone; Diabetes Mellitus; Humans; Hyperaldosteronism; Hypertension; Renin | 2020 |
CASZ1b is a novel transcriptional corepressor of mineralocorticoid receptor.
Topics: Aldosterone; Co-Repressor Proteins; DNA-Binding Proteins; Humans; Hypertension; Receptors, Mineraloc | 2021 |
Significance of Discordant Results Between Confirmatory Tests in Diagnosis of Primary Aldosteronism.
Topics: Adrenal Glands; Aged; Aldosterone; Blood Specimen Collection; Cross-Sectional Studies; Diagnosis, Di | 2021 |
Variability of Aldosterone Measurements During Adrenal Venous Sampling for Primary Aldosteronism.
Topics: Adrenal Glands; Aldosterone; Blood; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension | 2021 |
Association between renin-angiotensin-aldosterone system inhibitor use and COVID-19 hospitalization and death: a 1.4 million patient nationwide registry analysis.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; COVID-19; H | 2021 |
Effect of sodium-glucose cotransporter-2 inhibitors on aldosterone-to-renin ratio in diabetic patients with hypertension: a retrospective observational study.
Topics: Aged; Aldosterone; Diabetes Mellitus, Type 2; Female; Humans; Hyperaldosteronism; Hypertension; Male | 2020 |
Intraindividual Variability of Aldosterone Concentrations in Primary Aldosteronism: Implications for Case Detection.
Topics: Adult; Aldosterone; Biological Variation, Individual; Chromatography, Liquid; Female; Humans; Hypera | 2021 |
Paradoxical Increase of 24-Hour Urinary Aldosterone Levels in Obese Patients With Resistant Hypertension on a High Salt Diet.
Topics: Aldosterone; Cross-Sectional Studies; Humans; Hypertension; Obesity; Sodium Chloride, Dietary | 2021 |
Repeat Adrenal Vein Sampling in Aldosteronism: Reproducibility and Interpretation of Persistently Discordant Results.
Topics: Adrenal Glands; Adult; Aged; Aged, 80 and over; Aldosterone; Blood Specimen Collection; Catheterizat | 2021 |
[Dynamic changes of renin-angiotensin-aldosterone system parameters after surgery of primary hyperparathyroidism].
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Calcium; Humans; Hyperparathyroidism, Primary | 2020 |
[Primary aldosteronism: The Mayo Clinic approach].
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocortic | 2020 |
High prevalence and a long delay in the diagnosis of primary aldosteronism among patients with young-onset hypertension.
Topics: Adult; Aldosterone; Cross-Sectional Studies; Humans; Hyperaldosteronism; Hypertension; Middle Aged; | 2021 |
Salt Intake, Aldosterone Secretion, and Obesity: Role in the Pathogenesis of Resistant Hypertension.
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Obesity; Sodium Chloride, Dietary | 2021 |
Primary aldosteronism: considerations about the evaluation of the aldosterone to renin ratio during canrenone treatment.
Topics: Aldosterone; Antihypertensive Agents; Canrenone; Diagnostic Techniques, Endocrine; Duration of Thera | 2021 |
Exploration Of The Seated Saline Suppression Test For The Diagnosis Of Primary Aldosteronism In The Chinese Population.
Topics: Adrenocortical Adenoma; Aldosterone; Asian People; Humans; Hyperaldosteronism; Hypertension; Renin | 2020 |
Mineralocorticoid Receptor Antagonists Decrease the Rates of Positive Screening for Primary Aldosteronism.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Humans; Hyp | 2020 |
Aldosterone, gut microbiome and hypertension: selected papers from APCH 2019.
Topics: Aldosterone; Gastrointestinal Microbiome; Humans; Hypertension | 2021 |
Primary Aldosteronism: Strike Two.
Topics: Aldosterone; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hypertension | 2021 |
Growth differentiation factor 15 levels are similar in primary aldosteronism and essential hypertension and do not predict arterial inflammation.
Topics: Aldosterone; Arteritis; Essential Hypertension; Growth Differentiation Factor 15; Humans; Hyperaldos | 2021 |
Outcomes of Adrenalectomy and the Aldosteronoma Resolution Score in the Black and Hispanic Population.
Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Black or African American; Female; Hispanic or L | 2021 |
Automated Mindray CL-1200i chemiluminescent assays of renin and aldosterone for the diagnosis of primary aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Luminescent Measurements; Renin | 2021 |
Novel chemiluminescent immunoassay to measure plasma aldosterone and plasma active renin concentrations for the diagnosis of primary aldosteronism.
Topics: Aldosterone; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension; Radioimmunoassay; Ren | 2022 |
Primary aldosteronism investigation in the elderly: challenges and opportunities.
Topics: Aged; Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2021 |
A Flounder Fish Peptide Shows Anti-Hypertensive Effects by Suppressing the Renin-Angiotensin-Aldosterone System and Endothelin-1.
Topics: Administration, Oral; Aldosterone; Amino Acid Sequence; AMP-Activated Protein Kinases; Angiotensin I | 2021 |
Treatment of Primary Aldosteronism Increases Plasma Epoxyeicosatrienoic Acids.
Topics: Adrenalectomy; Adult; Aldosterone; Animals; Arachidonic Acids; Blood Pressure; Epoxide Hydrolases; F | 2021 |
Association of Serum Aldosterone and Plasma Renin Activity With Ambulatory Blood Pressure in African Americans: The Jackson Heart Study.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Black or African American; Blood Pressure; Female; Huma | 2021 |
Altered Taste Perception for Sodium Chloride in Patients With Primary Aldosteronism: A Prospective Cohort Study.
Topics: Adrenalectomy; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Min | 2021 |
Volumetric evaluation of CT images of adrenal glands in primary aldosteronism.
Topics: Adrenal Glands; Aldosterone; Antihypertensive Agents; Cone-Beam Computed Tomography; Correlation of | 2021 |
Evaluation of Hypokalemia.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Algorithms; Female; Humans; Hyperaldosteronism; Hyper | 2021 |
Seated Saline Suppression Test Is Comparable With Captopril Challenge Test for the Diagnosis of Primary Aldosteronism: A Prospective Study.
Topics: Aldosterone; Captopril; Humans; Hyperaldosteronism; Hypertension; Prospective Studies; Renin | 2021 |
[Primary aldosteronism: from diagnosis to therapy in clinical practice].
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Ant | 2021 |
Aldosterone-producing adenoma associated with non-suppressed renin: a case series.
Topics: Adenoma; Adrenocortical Adenoma; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male | 2022 |
Primary Aldosteronism with Parathyroid Hormone Elevation: A Single-center Retrospective Study.
Topics: Aldosterone; Calcium; Humans; Hyperaldosteronism; Hypertension; Parathyroid Hormone; Retrospective S | 2021 |
Association of aldosterone and blood pressure with the risk for cardiovascular events after treatments in primary aldosteronism.
Topics: Aldosterone; Blood Pressure; Cardiovascular Diseases; Female; Humans; Hyperaldosteronism; Hypertensi | 2021 |
Hypokalemia-Induced Rhabdomyolysis Caused by Adrenal Tumor-Related Primary Aldosteronism: A Report of 2 Cases.
Topics: Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; M | 2021 |
Prevalence, Subtype Classification, and Outcomes of Treatment of Primary Aldosteronism: A Prospective Study in China.
Topics: Aldosterone; China; Humans; Hyperaldosteronism; Hypertension; Prevalence; Prospective Studies; Renin | 2021 |
MicroRNA 21 and microRNA 155 levels in resistant hypertension, and their relationships with aldosterone.
Topics: Adult; Aged; Aldosterone; Blood Pressure Monitoring, Ambulatory; Case-Control Studies; Female; Human | 2021 |
[HYPERTENSION IN A YOUNG WOMAN WITH ANXIETY DISORDER: THE CHICKEN OR THE EGG?]
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Anxiety Disorder | 2021 |
Mineralocorticoid Receptor Antagonist Effect on Aldosterone to Renin Ratio in Patients With Primary Aldosteronism.
Topics: Adolescent; Adrenalectomy; Adult; Aged; Aldosterone; Canrenone; Cohort Studies; False Negative React | 2021 |
The Effects of Short-Term Changes in Sodium Intake on Plasma Marinobufagenin Levels in Patients with Primary Salt-Sensitive and Salt-Insensitive Hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Bufanolides; Female; Humans; Hypertension; Male; Midd | 2021 |
Hemodynamic and Non-Hemodynamic Components of Cardiac Remodeling in Primary Aldosteronism.
Topics: Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Blood Pressure; Echocardiography; Essenti | 2021 |
Aldosterone Secretion in Patients With Primary Hyperparathyroidism Without Arterial Hypertension.
Topics: Aldosterone; Humans; Hyperparathyroidism, Primary; Hypertension; Renin-Angiotensin System; Retrospec | 2021 |
Allisartan isoproxil reduces mortality of stroke-prone rats and protects against cerebrovascular, cardiac, and aortic damage.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Aorti | 2021 |
Urinary sodium/potassium ratio as a screening tool for hyperaldosteronism in men with hypertension.
Topics: Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potas | 2021 |
Aldosterone contributes to hypertension in male mice inducibly overexpressing human endothelin-1 in endothelium.
Topics: Aldosterone; Animals; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Humans; Hypertension; | 2021 |
Determination of adrenal hypersecretion in primary Aldosteronism without aldosterone-production adenomas.
Topics: Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Diagnosis, Differential; Female; Follow-Up Stud | 2021 |
Comparison of cystatin C-based and creatinine-based glomerular filtration rate in the prediction of postoperative residual hypertension in aldosterone-producing adenoma patients after adrenalectomy.
Topics: Adenoma; Adrenalectomy; Aldosterone; Biomarkers; Creatinine; Cystatin C; Glomerular Filtration Rate; | 2021 |
Characterization of the Renin-Angiotensin-Aldosterone System in Young Healthy Black Adults: The African Prospective Study on the Early Detection and Identification of Hypertension and Cardiovascular Disease (African-PREDICT Study).
Topics: Adult; Aldosterone; Angiotensin II; Black People; Blood Pressure; Cardiovascular Diseases; Early Dia | 2021 |
Letter to the Editor from Rui Zhu et al: "Performance of the Aldosterone-to-Renin Ratio as a Screening Test for Primary Aldosteronism: A Systematic Review and Meta-Analysis".
Topics: Aldosterone; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hypertension; Renin | 2021 |
Response Letter to the Editor from Zhu et al: "Performance of the Aldosterone-to-Renin Ratio as a Screening Test for Primary Aldosteronism: A Systematic Review and Meta-Analysis".
Topics: Aldosterone; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hypertension; Renin | 2021 |
Subtype-specific trends in the clinical picture of primary aldosteronism over a 13-year period.
Topics: Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Retro | 2021 |
Aldosterone hyperreactivity to acute psychosocial stress induction in men with essential hypertension.
Topics: Aldosterone; Blood Pressure; Essential Hypertension; Humans; Hypertension; Male; Stress, Psychologic | 2021 |
Does the Aldosterone: Renin Ratio Predict Future Blood Pressure in Young Adults?
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Renin; Renin-Angiotensin System; Young Adult | 2021 |
Associastion of In-hospital Use of Statins, Aspirin, and Renin-Angiotensin-Aldosterone Inhibitors with Mortality and ICU Admission Due to COVID-19.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensin | 2021 |
Prevalence of Primary Aldosteronism Across the Stages of Hypertension Based on a New Combined Overnight Test.
Topics: Adult; Aged; Aldosterone; Biomarkers; Case-Control Studies; Diagnostic Tests, Routine; Female; Follo | 2021 |
A case of primary aldosteronism with a negative aldosterone-to-renin ratio.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Biomarkers; B | 2021 |
Lipid Profiles in Primary Aldosteronism Compared with Essential Hypertension: Propensity-Score Matching Study.
Topics: Aldosterone; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension; Lipids; Retrospective | 2021 |
Aldosterone and Primary Aldosteronism: Star Performers in Hypertension Research.
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2021 |
Updates on Renin-Angiotensin System Blockers in Hypertensive Patients With COVID-19.
Topics: Aldosterone; Angiotensins; Antihypertensive Agents; COVID-19; Humans; Hypertension; Renin; Renin-Ang | 2021 |
Monogenic forms of low-renin hypertension: clinical and molecular insights.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin | 2022 |
Renin Phenotypes Characterize Vascular Disease, Autonomous Aldosteronism, and Mineralocorticoid Receptor Activity.
Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension; Linear Models; | 2017 |
Association of aldosterone excess and apnea-hypopnea index in patients with resistant hypertension.
Topics: Aged; Aldosterone; Coronary Vasospasm; Female; Humans; Hypertension; Male; Middle Aged; Sleep Apnea | 2017 |
Aldosterone a Relevant Factor in the Beginning and Evolution of Arterial Hypertension.
Topics: Aldosterone; Essential Hypertension; Humans; Hypertension; Renin | 2017 |
Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice.
Topics: Aldosterone; Animals; Biomarkers; Blood Pressure; Cytochrome P-450 CYP11B2; Electrolytes; Fadrozole; | 2017 |
Role and Regulation of MicroRNAs in Aldosterone-Mediated Cardiac Injury and Dysfunction in Male Rats.
Topics: Aldosterone; Animals; Gene Expression Regulation; Heart; Heart Diseases; Hyperaldosteronism; Hyperte | 2017 |
Urine exosomes from healthy and hypertensive pregnancies display elevated level of α-subunit and cleaved α- and γ-subunits of the epithelial sodium channel-ENaC.
Topics: Adult; Aldosterone; Epithelial Sodium Channels; Exosomes; Female; Fibrinolysin; Humans; Hypertension | 2017 |
Physiological and Pathological Roles in Human Adrenal of the Glomeruli-Defining Matrix Protein NPNT (Nephronectin).
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Cytochrome P-450 CYP11B2; Extracellular Matri | 2017 |
Relationship and associated mechanisms between ambulatory blood pressure and clinic blood pressure with prevalent cardiovascular disease in diabetic hypertensive patients.
Topics: Aged; Aldosterone; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Body Mass In | 2017 |
Hypertensive Patients That Respond to Aldosterone Antagonists May Have a Nonclassical 11β-HSD2 Deficiency.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Humans; Hypertension; Mineralocorticoid Re | 2017 |
Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: The aldosterone-mineralocorticoid receptor-Nox1 axis.
Topics: Acetylcholine; Aldosterone; Animals; Aorta; Blood Pressure; Galectin 3; Hypertension; Male; Mesenter | 2017 |
Aldosterone and Mineralocorticoid Receptors-Physiology and Pathophysiology.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenocorticotropic Hormone; Aldosterone; Animals; Arteries; | 2017 |
A case of confirmed primary hyperaldosteronism diagnosed despite normal screening investigations.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertens | 2017 |
Quantitative Value of Aldosterone-Renin Ratio for Detection of Aldosterone-Producing Adenoma: The Aldosterone-Renin Ratio for Primary Aldosteronism (AQUARR) Study.
Topics: Adrenocortical Adenoma; Aldosterone; Biomarkers, Tumor; Blood Pressure; Disease Progression; Female; | 2017 |
Rating the blood pressure outcome after adrenalectomy for unilateral primary aldosteronism.
Topics: Adrenalectomy; Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Retrospective | 2017 |
NEFM (Neurofilament Medium) Polypeptide, a Marker for Zona Glomerulosa Cells in Human Adrenal, Inhibits D1R (Dopamine D1 Receptor)-Mediated Secretion of Aldosterone.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cell Line, Tumor; Cell Proliferation; Dopamine Agonis | 2017 |
Of Mice and Man and the Regulation of Aldosterone Secretion.
Topics: Aldosterone; Biological Transport; Cell Communication; Humans; Hypertension | 2017 |
Rapid Diagnosis of Primary Aldosteronism: Oxymoron or One Small Step?
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2017 |
Rapid Screening of Primary Aldosteronism by a Novel Chemiluminescent Immunoassay.
Topics: Adult; Aldosterone; Antihypertensive Agents; Chromatography, Liquid; Comparative Effectiveness Resea | 2017 |
Characteristics of hypertension in premature infants with and without chronic lung disease: a long-term multi-center study.
Topics: Aldosterone; Antihypertensive Agents; Chronic Disease; Female; Humans; Hypertension; Infant; Infant, | 2017 |
Bypass of confirmatory tests for case detection of primary aldosteronism in leaner patients?
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Obesity; Thinness | 2017 |
Prevalence of primary aldosteronism without hypertension in the general population: Results in Shika study.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Disease Progression; Female; Humans; Hyperaldosteronism; H | 2018 |
Prenatal exposure to angiotensin II increases blood pressure and decreases salt sensitivity in rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Female; Heart Ventricles; Hypertension; Kidney | 2017 |
Associations between glycaemic control and activation of the renin-angiotensin-aldosterone system in participants with type 2 diabetes mellitus and hypertension.
Topics: Aged; Aldosterone; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glycat | 2018 |
Mineralocorticoids: the secret of muscle reflex dysfunction in hypertension?
Topics: Aldosterone; Animals; Hypertension; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Rats | 2017 |
Cerebrovascular recovery after stroke with individual and combined losartan and captopril treatment of SHRsp.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim | 2017 |
Screening of primary aldosteronism by clinical features and daily laboratory tests: combination of urine pH, sex, and serum K.
Topics: Adult; Aldosterone; Area Under Curve; Biomarkers; Female; Humans; Hydrogen-Ion Concentration; Hypera | 2018 |
Microalbuminuria and plasma aldosterone levels in nondiabetic treatment-naïve patients with hypertension.
Topics: Adult; Aged; Albuminuria; Aldosterone; Female; Humans; Hypertension; Hypertension, Renal; Kidney; Ki | 2017 |
Nocturnal diastolic blood pressure decline is associated with higher 25-hydroxyvitamin D level and standing plasma renin activity in a hypertensive population.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Blood Pressure; Blood Pres | 2017 |
Disruption of the with no lysine kinase-STE20-proline alanine-rich kinase pathway reduces the hypertension induced by angiotensin II.
Topics: Aldosterone; Amiloride; Angiotensin II; Animals; Blood Pressure; Diuretics; Epithelial Sodium Channe | 2018 |
Aldosterone induces left ventricular subclinical systolic dysfunction: a strain imaging study.
Topics: Adult; Aged; Aldosterone; Echocardiography; Essential Hypertension; Female; Heart; Humans; Hyperaldo | 2018 |
Favorable surgical outcomes of aldosterone-producing adenoma based on lateralization by CT imaging and hypokalemia: a non-AVS-based strategy.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi | 2017 |
Aldosterone to Renin Ratio as a Screening Instrument for Primary Aldosteronism in a Middle-Aged Population with Atrial Fibrillation.
Topics: Aldosterone; Atrial Fibrillation; Female; Humans; Hyperaldosteronism; Hypertension; Male; Mass Scree | 2017 |
Changes in plasma aldosterone and electrolytes levels, kidney epithelial sodium channel (ENaC) and blood pressure in normotensive WKY and hypertensive SHR rats following gonadectomy and chronic testosterone treatment.
Topics: Aldosterone; Animals; Blood Pressure; Castration; Disease Models, Animal; Electrolytes; Epithelial S | 2017 |
PECULIARITIES OF REMODELING OF HEART AND NEUROHUMORAL STATUS IN PATIENTS WITH CHRONIC HEART FAILURE AND CONCOMITANT RENAL DISEASE DEPENDING ON THE VALUE OF THE EJECTION FRACTION OF THE LEFT VENTRICLE.
Topics: Aldosterone; Chronic Disease; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Myocar | 2017 |
KCNJ5 mutation as a predictor for resolution of hypertension after surgical treatment of aldosterone-producing adenoma.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Female; G Prote | 2018 |
The Spectrum of Subclinical Primary Aldosteronism and Incident Hypertension: A Cohort Study.
Topics: Aged; Aged, 80 and over; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; H | 2017 |
Aldosterone-to-renin ratio depends on age and sex in children attending a clinic for cardiovascular risk assessment.
Topics: Adolescent; Age Factors; Aldosterone; Blood Pressure; Body Weight; Cardiovascular Diseases; Child; C | 2018 |
Urinary Cadmium Excretion Is Associated With Increased Synthesis of Cortico- and Sex Steroids in a Population Study.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aldosterone; Cadmium; Cohort Studies; Family; Female; Gonadal | 2018 |
Primary Hyperaldosteronism Due to Adrenocortical Adenoma: a Case Report.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Female; Humans; | 2017 |
Central and peripheral slow-pressor mechanisms contributing to Angiotensin II-salt hypertension in rats.
Topics: Aldosterone; Angiotensin II; Animals; Arterial Pressure; Brain; Cardenolides; Cardiovascular System; | 2018 |
Primary aldosteronism and cardiovascular risk, before and after treatment.
Topics: Aldosterone; Cardiovascular Diseases; Humans; Hyperaldosteronism; Hypertension; Risk Factors | 2018 |
Refining the Definitions of Biochemical and Clinical Cure for Primary Aldosteronism Using the Primary Aldosteronism Surgical Outcome (PASO) Classification System.
Topics: Adrenalectomy; Adult; Aged; Aldosterone; Biomarkers; Female; Humans; Hyperaldosteronism; Hypertensio | 2018 |
It's Complicated: How Often are Patients with Primary Aldosteronism Cured After Adrenalectomy?
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 2018 |
Mineralocorticoid receptor antagonism protects the aorta from vascular smooth muscle cell proliferation and collagen deposition in a rat model of adrenal aldosterone-producing adenoma.
Topics: ACTH-Secreting Pituitary Adenoma; Aldosterone; Animals; Antihypertensive Agents; Aorta; Cell Prolife | 2018 |
Misdiagnosis of a hidden cause of hypertension: a case report.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Diagnostic Errors; Female; Huma | 2017 |
Adrenal Vein Sampling Is the Preferred Method to Select Patients With Primary Aldosteronism for Adrenalectomy: Pro Side of the Argument.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Austra | 2018 |
Renin Activity and Aldosterone Assay Among Nigerians with Hypertension and Normotension: An Insight into Normative Values and Clinical Correlates.
Topics: Adult; Aldosterone; Biomarkers; Black People; Blood Pressure; Case-Control Studies; Cross-Sectional | 2018 |
Aldosterone as a mediator of microvascular and macrovascular damage in a population of normotensive to early-stage hypertensive individuals.
Topics: Adult; Albuminuria; Aldosterone; Blood Pressure; Correlation of Data; Female; Humans; Hypertension; | 2018 |
Double hit! A unique case of resistant hypertension.
Topics: Adrenal Glands; Aldosterone; Diuretics; Female; Humans; Hyperaldosteronism; Hyperparathyroidism, Pri | 2017 |
Mutations of the Twik-Related Acid-Sensitive K+ Channel 2 Promoter in Human Primary Aldosteronism.
Topics: Adrenocortical Adenoma; Adult; Aldosterone; Binding Sites; Female; Germ-Line Mutation; Humans; Hyper | 2018 |
Prevalence of primary aldosteronism in primary care: a cross-sectional study.
Topics: Adult; Aged; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; | 2018 |
RAGE-aptamer attenuates deoxycorticosterone acetate/salt-induced renal injury in mice.
Topics: Acetates; Acute Kidney Injury; Aldosterone; Animals; Aptamers, Peptide; Blood Pressure; Desoxycortic | 2018 |
Can aldosterone break your heart? Takotsubo cardiomyopathy in a patient with newly diagnosed primary aldosteronism.
Topics: Aldosterone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agen | 2018 |
Case detection in primary aldosteronism: high-diagnostic value of the aldosterone-to-renin ratio when performed under standardized conditions.
Topics: Adult; Aged; Aldosterone; False Negative Reactions; False Positive Reactions; Female; Humans; Hypera | 2018 |
Uterine fibroids and risk of hypertension: Implication of inflammation and a possible role of the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Cardiovascular Diseases; Female; Humans; Hypertension; Inflammation; Leiomyoma; Renin; | 2018 |
Plasma renin activity to plasma aldosterone concentration ratio for the assessment of essential hypertensive patients in real-life clinical practice.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Humans; Hypertension; Renin; | 2018 |
Primary aldosteronism: key characteristics at diagnosis: a trend toward milder forms.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Female; Germany; Humans; Hyperaldostero | 2018 |
Fluid retention, aldosterone excess, and treatment of resistant hypertension.
Topics: Aldosterone; Amiloride; Blood Pressure; Hemodynamics; Humans; Hypertension; Spironolactone | 2018 |
Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies.
Topics: Aldosterone; Amiloride; Antihypertensive Agents; Bisoprolol; Blood Pressure; Doxazosin; Female; Hemo | 2018 |
Licorice-induced apparent mineralocorticoid excess compounded by excessive use of terbutaline and high water intake.
Topics: Aldosterone; Asthma; Bronchodilator Agents; Diagnosis, Differential; Glycyrrhiza; Humans; Hypertensi | 2018 |
Olmesartan combined with renal denervation reduces blood pressure in association with sympatho-inhibitory and aldosterone-reducing effects in hypertensive mice with chronic kidney disease.
Topics: Albuminuria; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Combined Mo | 2019 |
Relationship between sodium, pentraxin-3 and aldosterone in inflammation and cardiovascular risk.
Topics: Aldosterone; C-Reactive Protein; Cardiovascular Diseases; Humans; Hypertension; Inflammation; Potass | 2018 |
Primary aldosteronism in patients with adrenal incidentaloma: Is screening appropriate for everyone?
Topics: Adrenal Gland Neoplasms; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypoka | 2018 |
Is the plasma aldosterone-to-renin ratio associated with blood pressure response to treatment in general practice?
Topics: Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pressure; Female; General Practice; Humans; | 2019 |
Role of Cryptochrome-1 and Cryptochrome-2 in Aldosterone-Producing Adenomas and Adrenocortical Cells.
Topics: Adenoma; Aldosterone; Angiotensin II; Animals; Cell Line, Tumor; Cryptochromes; Gene Expression Regu | 2018 |
Intestinal Mineralocorticoid Receptor Contributes to Epithelial Sodium Channel-Mediated Intestinal Sodium Absorption and Blood Pressure Regulation.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Colon; Diet, Sodium-Restricted; Disea | 2018 |
Chronic depression symptoms desensitize renin activity to protect against volume-loading hypertension in Blacks: The SABPA study.
Topics: Adult; Aldosterone; Black People; Blood Pressure; Depression; Female; Glomerular Filtration Rate; Hu | 2018 |
Beneficial effect of combined spironolactone and quinapril treatment on thrombosis and hemostasis in 2K1C hypertensive rats.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antigens, Tumor-Associated, Carbohyd | 2018 |
Inhibition of adenosine deaminase and xanthine oxidase by valproic acid abates hepatic triglyceride accumulation independent of corticosteroids in female rats treated with estrogen-progestin.
Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Aldosterone; Animals; Contraceptives, Oral, Com | 2018 |
[Efficacy of Screening and Confirmatory Tests of Primary Aldosteronism in Diagnosing Aldosterone Producing Adenoma].
Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Retrospective Studies | 2018 |
Untangling Essential Hypertension: The Potential Roles of Aldosterone and Atrial Natriuretic Peptide.
Topics: Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Essential Hypertension; Humans; Hyp | 2018 |
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L | 2018 |
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L | 2018 |
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L | 2018 |
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L | 2018 |
Spectrum of renin angiotensin aldosterone system disorders in young hypertensives.
Topics: Adolescent; Adult; Aldosterone; Blood Gas Analysis; Cross-Sectional Studies; Electrolytes; Humans; H | 2018 |
Aldosterone LC-MS/MS Assay-Specific Threshold Values in Screening and Confirmatory Testing for Primary Aldosteronism.
Topics: Adult; Aged; Aldosterone; Chromatography, High Pressure Liquid; Diagnostic Techniques, Endocrine; Fe | 2018 |
Aldosterone overload: An overlooked cause of high blood pressure?
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2018 |
Relationship between water and salt intake, osmolality, vasopressin, and aldosterone in the regulation of blood pressure.
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Osmolar Concentration; Sodium Chloride, Dietary; | 2018 |
Adrenal Vein Sampling Lateralization Despite Mineralocorticoid Receptor Antagonists Exposure in Primary Aldosteronism.
Topics: Adrenal Glands; Adult; Aged; Aldosterone; Blood Specimen Collection; False Negative Reactions; Femal | 2019 |
Renin-producing germ cell tumor in the pineal apparatus and mediastinum: A rare case report.
Topics: Adult; Aldosterone; Craniotomy; Humans; Hypertension; Male; Mediastinal Neoplasms; Neoplasms, Germ C | 2018 |
The eNOS-NO pathway attenuates kidney dysfunction via suppression of inflammasome activation in aldosterone-induced renal injury model mice.
Topics: Aldosterone; Animals; Antihypertensive Agents; Disease Models, Animal; Endothelium; Fibrosis; Humans | 2018 |
Increased Fibroblast Growth Factor 23 in Heart Failure: Biomarker, Mechanism, or Both?
Topics: Aldosterone; Biomarkers; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Heart Failure; Huma | 2019 |
Cellular and Genetic Causes of Idiopathic Hyperaldosteronism.
Topics: Aldosterone; Calcium Channels, L-Type; Cytochrome P-450 CYP11B2; Female; G Protein-Coupled Inwardly- | 2018 |
Endothelial cell mineralocorticoid receptors oppose VEGF-induced gene expression and angiogenesis.
Topics: Aldosterone; Animals; Aorta; Cells, Cultured; Desoxycorticosterone Acetate; Disease Models, Animal; | 2019 |
Predictors of confirmatory test results for the diagnosis of primary hyperaldosteronism in hypertensive patients with an aldosterone-to-renin ratio greater than 20. The SHRIMP study.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hype | 2019 |
Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study.
Topics: Adult; Aldosterone; Ankle Brachial Index; Antihypertensive Agents; Blood Pressure; Brachial Artery; | 2019 |
Speckle-Tracking Echocardiographic Layer-Specific Strain Analysis on Subclinical Left Ventricular Dysfunction in Patients With Primary Aldosteronism.
Topics: Adult; Aged; Aldosterone; Asymptomatic Diseases; Biomarkers; Blood Pressure; Case-Control Studies; C | 2019 |
Effects of mineralocorticoid and AT-1 receptor antagonism on the aldosterone-renin ratio (ARR) in primary aldosteronism patients (EMIRA Study): rationale and design.
Topics: Adult; Aged; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Female; Humans; Hyperaldosteronis | 2019 |
The exaggerated salt-sensitive response in hypertensive transgenic rats (TGR mRen-2) fostered by a normotensive female.
Topics: Aldosterone; Animals; Blood Pressure; Female; Hypertension; Kidney; Male; Rats; Rats, Transgenic; Re | 2019 |
Changes in serum and intracardiac fibroblast growth factor 23 during the progression of left ventricular hypertrophy in hypertensive model rats.
Topics: Aldosterone; Animals; Bone and Bones; Chronic Kidney Disease-Mineral and Bone Disorder; Disease Mode | 2019 |
Lack of Suppression of Aldosterone Production Leads to Salt-Sensitive Hypertension in Female but Not Male Balb/C Mice.
Topics: Adrenal Glands; Aldosterone; Angiotensinogen; Animals; Blood Pressure; Female; Hypertension; Male; M | 2018 |
Aldosterone and 18-Oxocortisol Coaccumulation in Aldosterone-Producing Lesions.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Female; Humans; | 2018 |
Rates of abnormal aldosterone/renin ratio in African-origin compared to European-origin patients: A retrospective study.
Topics: Adult; Africa; Aldosterone; Echocardiography; Female; Humans; Hyperaldosteronism; Hypertension; Hypo | 2019 |
Adrenal Tissue-Specific Deletion of TASK Channels Causes Aldosterone-Driven Angiotensin II-Independent Hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Hypertension; Male; Mice; Mice, Knockout; Nerve Tissue Protein | 2019 |
Impact of adrenocorticotropic hormone stimulation during adrenal venous sampling on outcomes of primary aldosteronism.
Topics: Adrenal Glands; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Co | 2019 |
Frequency of Primary Hyperaldosteronism in Young Hypertensives in a Tertiary Care Setting of Rawalpindi.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Cross-Sectional Studies; Female; Humans; Hyperaldost | 2019 |
Mineralocorticoid Receptor Antagonists.
Topics: Aldosterone; Animals; Antihypertensive Agents; Heart Failure; Humans; Hypertension; Mineralocorticoi | 2019 |
Family hyperaldosteronism type I: a clinical case and review of literature.
Topics: Adrenalectomy; Aldosterone; Antihypertensive Agents; Blood Pressure; Corticosterone; Cytochrome P-45 | 2018 |
[Two case reports on resistant hypertension].
Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension | 2019 |
The Aldosterone/Renin Ratio Predicts Cardiometabolic Disorders in Subjects Without Classic Primary Aldosteronism.
Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Cross-Sectional Studies; Disease Progression; Female | 2019 |
Evaluation of Biochemical Conditions Allowing Bypass of Confirmatory Testing in The Workup of Primary Aldosteronism: A Retrospective Study in a French Hypertensive Population.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Female; Humans; Hyperaldosteronism; Hyperte | 2019 |
[Corticosurrenaloma: an exceptional cause of primary hyperaldosteronism].
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Glucocorticoids; Hepatectomy; Humans; Hyperaldosteronis | 2018 |
Hypertension in pregnancy: Role of body mass index, insulin resistance, aldosterone, and calcium homeostasis.
Topics: Aldosterone; Body Mass Index; Calcium; China; Cross-Sectional Studies; Female; Homeostasis; Humans; | 2019 |
CaseReport: Aldosterone-secreting adrenal carcinoma complicating longstanding hypertension.
Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Carcinoma; Humans; H | 2020 |
Long-term BP control and vascular health in patients with hyperaldosteronism treated with low-dose, amiloride-based therapy.
Topics: Aftercare; Aldosterone; Amiloride; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitorin | 2019 |
Hypertension with primary aldosteronism is associated with increased carotid intima-media thickness and endothelial dysfunction.
Topics: Aldosterone; Antihypertensive Agents; Brachial Artery; Carotid Arteries; Carotid Intima-Media Thickn | 2019 |
Subclinical atherosclerosis due to increase of plasma aldosterone concentrations in essential hypertensive individuals.
Topics: Adult; Aldosterone; Ankle Brachial Index; Atherosclerosis; Biomarkers; Carotid Intima-Media Thicknes | 2019 |
Primary Aldosteronism: Does Underlying Pathology Impact Clinical Presentation and Outcomes Following Unilateral Adrenalectomy?
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Female; Humans; | 2019 |
Sex Difference in the Association Between Subtype Distribution and Age at Diagnosis in Patients With Primary Aldosteronism.
Topics: Adrenalectomy; Adult; Age Distribution; Age of Onset; Aged; Aldosterone; Databases, Factual; Female; | 2019 |
The captopril challenge test for diagnosing primary Aldosteronism in a Chinese population.
Topics: Adult; Aldosterone; Captopril; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; | 2019 |
[Primary hyperaldosteronism in a population of hypertensive patients].
Topics: Aged; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2019 |
Maintenance of long-term blood pressure control and vascular health by low-dose amiloride-based therapy in hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Albuminuria; Aldosterone; Amiloride; Ankle Brachial Index; | 2019 |
Excess Arterial Damage in Hyperaldosteronism.
Topics: Aldosterone; Arteries; Humans; Hyperaldosteronism; Hypertension | 2019 |
Aldosterone Induces Vascular Damage.
Topics: Adult; Aldosterone; Antihypertensive Agents; Area Under Curve; Arterial Pressure; Cohort Studies; Cr | 2019 |
Body mass index predicts aldosterone production in hypertensive postmenopausal women.
Topics: Adult; Aldosterone; Body Mass Index; China; Correlation of Data; Cross-Sectional Studies; Estrogens; | 2020 |
Familial hyperkalemia and hypertension and a hypothesis to explain proximal renal tubular acidosis.
Topics: Acidosis, Renal Tubular; Aldosterone; Chlorides; Humans; Hyperkalemia; Hypertension; Protein Serine- | 2019 |
The changing spectrum of hypertension in premature infants.
Topics: Aldosterone; Antihypertensive Agents; Creatinine; Female; Humans; Hypertension; Infant, Low Birth We | 2019 |
Urinary sodium excretion is the main determinant of mineralocorticoid excretion rates in patients with chronic kidney disease.
Topics: Aldosterone; Cohort Studies; Corticosterone; Cross-Sectional Studies; Essential Hypertension; Female | 2013 |
Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Calcium; Cells, Cultured; Electrophys | 2013 |
Regression of albuminuria and hypertension and arrest of severe renal injury by a losartan-hydrochlorothiazide association in a model of very advanced nephropathy.
Topics: Acute Kidney Injury; Albuminuria; Aldosterone; Animals; Antihypertensive Agents; Drug Therapy, Combi | 2013 |
Predominance of AT(1) blockade over mas-mediated angiotensin-(1-7) mechanisms in the regulation of blood pressure and renin-angiotensin system in mRen2.Lewis rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihy | 2013 |
Factors affecting complete hypertension cure after adrenalectomy for aldosterone-producing adenoma: outcomes in a large series.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Antihypertensive Agents; Blood | 2013 |
Blood pressure variability activates cardiac mineralocorticoid receptor and induces cardiac remodeling in hypertensive rats.
Topics: Active Transport, Cell Nucleus; Aldosterone; Animals; Blood Pressure; Cardiomegaly; Cell Nucleus; Ep | 2013 |
Aldosterone levels and inflammatory stimulation in essential hypertensive patients.
Topics: Adult; Aged; Aldosterone; Biomarkers; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; C | 2013 |
Medical or surgical therapy for primary aldosteronism: post-treatment follow-up as a surrogate measure of comparative outcomes.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Antihypertensiv | 2013 |
Additional antihypertensive effect of magnesium supplementation with an angiotensin II receptor blocker in hypomagnesemic rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agen | 2013 |
Aldosterone excess impairs first phase insulin secretion in primary aldosteronism.
Topics: Adult; Aldosterone; Blood Glucose; Female; Humans; Hyperaldosteronism; Hypertension; Insulin; Insuli | 2013 |
Hormones other than aldosterone may contribute to hypertension in 3 different subtypes of primary aldosteronism.
Topics: Adrenal Medulla; Adult; Aldosterone; Blood Pressure Determination; Female; Glucocorticoids; Humans; | 2013 |
Serum dehydroepiandrosterone sulfate concentration is lower in women with primary aldosteronism.
Topics: Adenoma; Adult; Aged; Aldosterone; Cholesterol, HDL; Creatinine; Dehydroepiandrosterone Sulfate; Ess | 2015 |
High sodium intake is associated with increased glucocorticoid production, insulin resistance and metabolic syndrome.
Topics: Adiponectin; Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Blood Glucose; Body Mass Index | 2014 |
Rhabdomyolysis presenting with severe hypokalemia in hypertensive patients: a case series.
Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperald | 2013 |
Renin angiotensin antagonists normalize aberrant activation of epithelial sodium channels in sodium-sensitive hypertension.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Do | 2012 |
Hypertension and depressed symptomatology: a cluster related to the activation of the renin-angiotensin-aldosterone system (RAAS). Findings from population based KORA F4 study.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Cross-Sectional Studies; Depression; Female; Germany; H | 2013 |
Estrogen receptor-β in the paraventricular nucleus and rostroventrolateral medulla plays an essential protective role in aldosterone/salt-induced hypertension in female rats.
Topics: Aldosterone; Animals; Animals, Newborn; Blood Pressure; Cells, Cultured; Disease Models, Animal; Est | 2013 |
Spironolactone prevents dietary-induced metabolic syndrome by inhibiting PI3-K/Akt and p38MAPK signaling pathways.
Topics: Aldosterone; Animals; Apoptosis; Diet, High-Fat; Dyslipidemias; Hypertension; Insulin-Secreting Cell | 2013 |
Novel mechanism for disrupted circadian blood pressure rhythm in a rat model of metabolic syndrome--the critical role of angiotensin II.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Circadian Rhythm; Disease Models, Animal; Hype | 2013 |
Bone health and aldosterone excess.
Topics: Absorptiometry, Photon; Adult; Aged; Aldosterone; Bone Density; Calcium; Essential Hypertension; Fem | 2013 |
Prevalence and clinical characteristics of primary aldosteronism in Japanese patients with type 2 diabetes mellitus and hypertension.
Topics: Aged; Aldosterone; Angiotensin Receptor Antagonists; Antihypertensive Agents; Asian People; Diabetes | 2013 |
Incidence and factors of post-adrenalectomy hyperkalemia in patients with aldosterone producing adenoma.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Female; H | 2013 |
[Effect of Rhodiola Sacra on left ventricular remodeling and its mechanism in spontaneously hypertensive rats].
Topics: Aldosterone; Angiotensin II; Animals; Drugs, Chinese Herbal; Hypertension; Male; Rats; Rats, Inbred | 2013 |
Echocardiographic effects of eplerenone and aldosterone in hypertensive rats.
Topics: Aldosterone; Animals; Echocardiography; Eplerenone; Hypertension; Male; Rats; Rats, Inbred SHR; Rats | 2013 |
Bimodal aldosterone distribution in low-renin hypertension.
Topics: Aged; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2013 |
Inadequate RAAS suppression is associated with excessive left ventricular mass and systo-diastolic dysfunction.
Topics: Adult; Aldosterone; Blood Pressure Monitoring, Ambulatory; Cross-Sectional Studies; Echocardiography | 2013 |
Primary aldosteronism: emerging trends.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Renin | 2013 |
Central endogenous angiotensin-(1-7) protects against aldosterone/NaCl-induced hypertension in female rats.
Topics: Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models | 2013 |
Comparison of 24-h urinary aldosterone level and random urinary aldosterone-to-creatinine ratio in the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Creatinine; Essential Hypertension; Female; Hu | 2013 |
Quantification of urinary 18-hydroxycortisol using LC-MS/MS.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Biomarkers, Tumor; Chromatography, Liquid; Essential | 2013 |
Stimulation of aldosterone synthesis by angiotensin II in the brain: support for positive feedback in hypertension?
Topics: Aldosterone; Animals; Brain; Corticosterone; Hypertension; Male | 2013 |
Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Brain; Corticosterone; Cytochrome P-450 CYP11B | 2013 |
Synergic effect of high renin and aldosterone levels on inappropriate left ventricular mass and systolic function: a tissue Doppler study.
Topics: Adult; Aldosterone; Biomarkers; Echocardiography, Doppler; Female; Humans; Hypertension; Male; Renin | 2013 |
Nebivolol: a multifaceted antioxidant and cardioprotectant in hypertensive heart disease.
Topics: Aldosterone; Animals; Antioxidants; Benzopyrans; Calcium; Cardiotonic Agents; Cytosol; Disease Model | 2013 |
Complement 3 activates the renal renin-angiotensin system by induction of epithelial-to-mesenchymal transition of the nephrotubulus in mice.
Topics: Aldosterone; Amides; Angiotensin II; Animals; Antihypertensive Agents; Complement C3; Epithelial-Mes | 2013 |
NT-proBNP, a useful tool in hypertensive patients undergoing a diagnostic evaluation for primary aldosteronism.
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Natriuretic | 2014 |
Female sex hormones are associated with the reduction of serum sodium and hypertension complications in patients with aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Biomarkers; Cerebrovascular Disorders; | 2013 |
Blood pressure control 1 year after referral to a hypertension specialist.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Cohort Studies; Female; Follow-Up | 2013 |
Effects of salt status and blockade of mineralocorticoid receptors on aldosterone-induced cardiac injury.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Echocardiography; Endoth | 2014 |
Lethal liquorice lollies (liquorice abuse causing pseudohyperaldosteronism).
Topics: Aldosterone; Diagnosis, Differential; Electrocardiography; Female; Follow-Up Studies; Glycyrrhiza; H | 2013 |
Evaluation of docosahexaenoic acid in a dog model of hypertension induced left ventricular hypertrophy.
Topics: Aldosterone; Animals; Arachidonic Acid; Blood Pressure; Disease Models, Animal; Docosahexaenoic Acid | 2013 |
Prognosis of primary aldosteronism in Japan: results from a nationwide epidemiological study.
Topics: Adenoma; Aldosterone; Epidemiologic Studies; Female; Health Surveys; Humans; Hyperaldosteronism; Hyp | 2014 |
Combined antihypertensive effect of luteolin and buddleoside enriched extracts in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Drug Therapy, Combination; Endothelin | 2013 |
Somatic ATP1A1, ATP2B3, and KCNJ5 mutations in aldosterone-producing adenomas.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Cytochrome P-450 CYP11B2; Fema | 2014 |
Telmisartan delays myocardial fibrosis in rats with hypertensive left ventricular hypertrophy by TGF-β1/Smad signal pathway.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzo | 2014 |
Blood pressure and neurohormonal responses to renal nerve ablation in treatment-resistant hypertension.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Denervati | 2014 |
Cushing's disease and hypertension: in vivo and in vitro study of the role of the renin-angiotensin-aldosterone system and effects of medical therapy.
Topics: Adult; Aged; Aldosterone; Angiotensinogen; Animals; Cabergoline; Ergolines; Female; Humans; Hyperten | 2014 |
Aldosterone blockade reduces mortality without changing cardiac remodeling in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Electrocardiography; Gene Expression Regulation; Hy | 2013 |
[Correlation between plasma aldosterone concentration and left ventricular structure in hypertensive patients].
Topics: Adolescent; Adult; Aged; Aldosterone; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, L | 2013 |
Aldosterone testing: evaluation of a novel automated immunoassay.
Topics: Aldosterone; Case-Control Studies; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Limit of D | 2014 |
Smooth muscle cell mineralocorticoid receptors are mandatory for aldosterone-salt to induce vascular stiffness.
Topics: Aldosterone; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Male; Mice; Mice, Transg | 2014 |
Renal denervation: still more questions than answers.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Denervation; Endothelin-1; Humans; Hypertensio | 2014 |
Long-term prehypertension treatment with losartan effectively prevents brain damage and stroke in stroke-prone spontaneously hypertensive rats.
Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Apoptosis; Blood Pressure; Brain; Hypertension; Lo | 2014 |
M-atrial natriuretic peptide and nitroglycerin in a canine model of experimental acute hypertensive heart failure: differential actions of 2 cGMP activating therapeutics.
Topics: Aldosterone; Angiotensin II; Animals; Arterial Pressure; Atrial Natriuretic Factor; Cardiac Pacing, | 2014 |
Modulation of aldosterone levels by -344 C/T CYP11B2 polymorphism and spironolactone use in resistant hypertension.
Topics: Aged; Aldosterone; Alleles; Blood Pressure; Cytochrome P-450 CYP11B2; DNA; Female; Genotype; Humans; | 2014 |
Reninoma: the importance of renal vein renin ratios for lateralisation and diagnosis.
Topics: Adolescent; Adult; Aldosterone; Antihypertensive Agents; Captopril; Enalaprilat; Female; Humans; Hyp | 2014 |
[Analysis of characteristics of renin, aldosterone and aldosterone/renin ratio in patients with aldosterone-producing adenoma].
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Case-Control Studies; Essential Hypertension; Female; H | 2013 |
Autocrine and paracrine function of Angiotensin 1-7 in tissue repair during hypertension.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Aut | 2014 |
Renin-angiotensin-aldosterone-blockade is associated with decreased use of antidepressant therapy in patients with type 1 diabetes and diabetic nephropathy.
Topics: Adult; Aged; Aldosterone; Angiotensins; Antidepressive Agents; Antihypertensive Agents; Cross-Sectio | 2014 |
Methylglyoxal, a reactive glucose metabolite, increases renin angiotensin aldosterone and blood pressure in male Sprague-Dawley rats.
Topics: Aldosterone; Angiotensins; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Catecholami | 2014 |
Association of renin and aldosterone with ethnicity and blood pressure: the Multi-Ethnic Study of Atherosclerosis.
Topics: Aged; Aged, 80 and over; Aldosterone; Asian People; Atherosclerosis; Biomarkers; Black or African Am | 2014 |
Measurement of plasma renin concentration instead of plasma renin activity decreases the positive aldosterone-to-renin ratio tests in treated patients with essential hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Blood Chemical Ana | 2014 |
Exploring the role of aldosterone in right ventricular function.
Topics: Aldosterone; Blood Pressure; Female; Heart Ventricles; Humans; Hypertension; Male; Renin; Renin-Angi | 2014 |
Abnormal regulation of renin angiotensin aldosterone system is associated with right ventricular dysfunction in hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Echocardiography, Doppler; Female; Heart Ventricles; Humans; Hyp | 2014 |
Is adrenal venous sampling mandatory before surgical decision in case of primary hyperaldosteronism?
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Blood Pressure; | 2014 |
Corticosterone-activated mineralocorticoid receptor contributes to salt-induced sympathoexcitation in pressure overload mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenalectomy; Aldosterone; Animals; Corticosterone; Hy | 2014 |
Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma.
Topics: Adenoma; Adrenal Glands; Adult; Aged; Aldosterone; Antigens, Neoplasm; Biomarkers; Case-Control Stud | 2014 |
[Influence factors of salt-sensitive hypertension and responses of blood pressure and urinary sodium and potassium excretion to acute oral saline loading among essential hypertensive patients].
Topics: Adult; Aged; Aldosterone; Blood Pressure; Electrolytes; Essential Hypertension; Female; Humans; Hype | 2013 |
Aldosterone to active Renin ratio as screening test for primary aldosteronism: reproducibility and influence of orthostasis and salt loading.
Topics: Aldosterone; Cohort Studies; Dizziness; Essential Hypertension; Female; Humans; Hyperaldosteronism; | 2014 |
Endothelial cell mineralocorticoid receptors regulate deoxycorticosterone/salt-mediated cardiac remodeling and vascular reactivity but not blood pressure.
Topics: Aldosterone; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cells, Cultured; Conne | 2014 |
Adiponectin as an independent predictor of left ventricular hypertrophy in nondiabetic patients with hypertension.
Topics: Adiponectin; Aged; Aldosterone; Biomarkers; Female; Hemodynamics; Humans; Hypertension; Hypertrophy, | 2015 |
Aldosterone receptor blockers spironolactone and canrenone: two multivalent drugs.
Topics: Albuminuria; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Canrenone; Humans; Hypertension; | 2014 |
Hypokalaemia in a hyperthyroid domestic shorthair cat with adrenal hyperplasia.
Topics: Adrenal Glands; Adrenocortical Hyperfunction; Aldosterone; Amlodipine; Animals; Carbimazole; Cat Dis | 2014 |
The unique response of renin and aldosterone to dietary sodium intervention in sodium sensitivity.
Topics: Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Age | 2014 |
Effect of obstructive respiratory events on blood pressure and renal perfusion in a pig model for sleep apnea.
Topics: Aldosterone; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Creatinine; Disea | 2014 |
The velocity of home blood pressure reduction in response to low-dose eplerenone combined with other antihypertensive drugs determined by exponential decay function analysis.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure | 2014 |
Aldosterone-to-renin ratio and nocturnal blood pressure decline assessed by self-measurement of blood pressure at home: the Ohasama Study.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure | 2014 |
Primary aldosteronism and essential hypertension: assessment of cardiovascular risk at diagnosis and after treatment.
Topics: Adult; Aged; Aldosterone; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Essential Hyperten | 2014 |
Urinary angiotensinogen as a potential biomarker of intrarenal renin-angiotensin system activity in Chinese chronic kidney disease patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Angiotensinogen; Asian Peop | 2015 |
Aldosterone to active renin ratio is associated with nocturnal blood pressure in obese and treated hypertensive patients: the Styrian Hypertension Study.
Topics: Aged; Aldosterone; Antihypertensive Agents; Austria; Blood Pressure; Blood Pressure Monitoring, Ambu | 2014 |
Negative association between plasma aldosterone concentration/plasma renin activity and morning blood pressure surge in never-treated hypertensive patients.
Topics: Aldosterone; Ankle Brachial Index; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory | 2014 |
Adiponectin and Aldosterone in Left Ventricular Hypertrophy: An Intriguing Interplay.
Topics: Adiponectin; Aldosterone; Humans; Hypertension; Hypertrophy, Left Ventricular | 2018 |
CNS neuroplasticity and salt-sensitive hypertension induced by prior treatment with subpressor doses of ANG II or aldosterone.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain; Brain-Derived | 2014 |
Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and exacerbates angiotensin II-mediated hypertension.
Topics: Adaptor Proteins, Signal Transducing; Aldosterone; Angiotensin II; Angiotensinogen; Animals; Blood P | 2014 |
Mizoribine ameliorates renal injury and hypertension along with the attenuation of renal caspase-1 expression in aldosterone-salt-treated rats.
Topics: Aldosterone; Animals; Blood Pressure; Caspase 1; DNA Nucleotidylexotransferase; Epithelial Sodium Ch | 2014 |
[Suppression test to diagnose hyperaldosteronism in cats].
Topics: Aldosterone; Animals; Cat Diseases; Cats; Hyperaldosteronism; Hypertension | 2014 |
Racial differences in sensitivity of blood pressure to aldosterone.
Topics: Adolescent; Adult; Aldosterone; Analysis of Variance; Anti-Inflammatory Agents; Black or African Ame | 2014 |
Heme oxygenase suppresses markers of heart failure and ameliorates cardiomyopathy in L-NAME-induced hypertension.
Topics: Adiponectin; Aldosterone; Animals; Antioxidants; Arginine; Atrial Natriuretic Factor; Biomarkers; Bl | 2014 |
Adipokines: another link between obesity and hypertension.
Topics: Aldosterone; Humans; Hypertension; Obesity | 2015 |
Editorial: New horizon in the treatment of hypertension--role for Ca channel blockers--why do Ca channel blockers be focused on?
Topics: Aldosterone; Calcium Channel Blockers; Edema; Heart; Humans; Hypertension; Renal Insufficiency, Chro | 2013 |
KCNJ5 gene somatic mutations affect cardiac remodelling but do not preclude cure of high blood pressure and regression of left ventricular hypertrophy in primary aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Female; Follow-Up Studies; G Protein- | 2014 |
Small dedifferentiated cardiomyocytes bordering on microdomains of fibrosis: evidence for reverse remodeling with assisted recovery.
Topics: Aldosterone; Animals; Antioxidants; Cell Dedifferentiation; Cell Differentiation; Fibrosis; Hyperten | 2014 |
Reduction of plasma aldosterone and arterial stiffness in obese pre- and stage1 hypertensive subjects after aerobic exercise.
Topics: Aldosterone; Biomarkers; Blood Pressure; Down-Regulation; Exercise Therapy; Female; Humans; Hyperten | 2015 |
[Farmacological effect of retabolil on aldosterone level and arterial pressure in rats under the action of vibrations].
Topics: Aldosterone; Anabolic Agents; Animals; Arterial Pressure; Hypertension; Male; Mineralocorticoid Rece | 2014 |
Clinical outcomes in patients undergoing laparoscopic adrenalectomy for unilateral aldosterone producing adenoma: partial versus total adrenalectomy.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Blood Pressure; Female; H | 2014 |
Lack of RAAS inhibition by high-salt intake is associated with arterial stiffness in hypertensive patients.
Topics: Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System; Sodiu | 2014 |
High-probability features of primary aldosteronism may obviate the need for confirmatory testing without increasing false-positive diagnoses.
Topics: Adrenal Glands; Adult; Aldosterone; False Positive Reactions; Female; Humans; Hydrocortisone; Hypera | 2014 |
Association between urine aldosterone and diastolic function in patients with primary aldosteronism and essential hypertension.
Topics: Adult; Aldosterone; Echocardiography; Essential Hypertension; Female; Humans; Hyperaldosteronism; Hy | 2014 |
Primary aldosteronism in hypertensive patients: clinical implications and target therapy.
Topics: Adrenocorticotropic Hormone; Aldosterone; Antihypertensive Agents; Case-Control Studies; Female; Hum | 2014 |
Hypotensive effect of retabolil correcting the concentration of aldosterone during stress exposures.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Male; Nandrolone; Nandr | 2014 |
Association of aldosterone-to-renin ratio with hypertension differs by sodium intake: the Ohasama study.
Topics: Aged; Aldosterone; Female; Humans; Hypertension; Incidence; Japan; Longitudinal Studies; Male; Middl | 2015 |
Oxidative stress in patients affected by primary aldosteronism.
Topics: Adenoma; Adrenalectomy; Adult; Aged; Aldosterone; Essential Hypertension; Female; Humans; Hyperaldos | 2014 |
Aldosterone-renin ratio in the assessment of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; | 2014 |
The blood pressure-lowering effect of renal denervation is inversely related to kidney function.
Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; C | 2014 |
The value of losartan suppression test in the confirmatory diagnosis of primary aldosteronism in patients over 50 years old.
Topics: Aldosterone; Captopril; Demography; Female; Humans; Hyperaldosteronism; Hypertension; Losartan; Male | 2015 |
Increased salt intake during early ontogenesis lead to development of arterial hypertension in salt-resistant Wistar rats.
Topics: Adaptor Proteins, Signal Transducing; Aldosterone; Animals; Blood Pressure; Blotting, Western; Disea | 2015 |
A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium.
Topics: Adenoma; Adrenal Cortex; Adrenocortical Adenoma; Aged; Aldosterone; Antihypertensive Agents; Cell Li | 2014 |
Introgressed chromosome 2 quantitative trait loci restores aldosterone regulation and reduces response to salt in the stroke-prone spontaneously hypertensive rat.
Topics: Aldosterone; Animals; Chromosomes; Genotype; Hypertension; Kidney; Male; Quantitative Trait Loci; Ra | 2014 |
Albumin may prevent hypertension by inhibiting renin angiotensin aldosterone system.
Topics: Aldosterone; Cohort Studies; Female; Humans; Hypertension; Japan; Male; Potassium; Renin-Angiotensin | 2014 |
Vitamin D modulates the association of circulating insulin-like growth factor-1 with carotid artery intima-media thickness.
Topics: Aged; Aged, 80 and over; Aging; Albuminuria; Aldosterone; Apoptosis; Baltimore; Body Mass Index; Car | 2014 |
The influence of aging on the diagnosis of primary aldosteronism.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captop | 2014 |
RAAS and stress markers in acute ischemic stroke: preliminary findings.
Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Animals; Biomarkers; Blood Pressure; Female; H | 2015 |
Synergic effects of renin and aldosterone on right ventricular function in hypertension: a tissue Doppler study.
Topics: Adult; Aldosterone; Anthropometry; Biomarkers; Echocardiography, Doppler; Female; Heart Ventricles; | 2015 |
Decreased plasma prorenin levels in primary aldosteronism: potential diagnostic implications.
Topics: Adenoma; Adult; Aldosterone; Cohort Studies; Essential Hypertension; Female; Humans; Hyperaldosteron | 2015 |
Primary aldosteronism: functional histopathology and long-term follow-up after unilateral adrenalectomy.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Cytochrome P- | 2015 |
Beneficial effects of proanthocyanidins in the cardiac alterations induced by aldosterone in rat heart through mineralocorticoid receptor blockade.
Topics: Aldosterone; Animals; Cell Line; Chlorocebus aethiops; Heart; Hypertension; Immediate-Early Proteins | 2014 |
[How to unravel hyperaldosteronism in clinical practice].
Topics: Aldosterone; Algorithms; Antihypertensive Agents; Diagnosis, Differential; Drug Resistance; Humans; | 2014 |
Aldosteronoma resolution score predicts long-term resolution of hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure Determination; C | 2014 |
Effects of cilnidipine on sympathetic nerve activity and cardiorenal function in hypertensive patients with type 2 diabetes mellitus: association with BNP and aldosterone levels.
Topics: Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, T | 2014 |
Renal BOLD-MRI relates to kidney function and activity of the renin-angiotensin-aldosterone system in hypertensive patients.
Topics: Aged; Aldosterone; Blood Pressure; Creatinine; Female; Glomerular Filtration Rate; Humans; Hypertens | 2015 |
Inhibitory effect of D3 dopamine receptor on migration of vascular smooth muscle cells induced by synergistic effect of angiotensin II and aldosterone.
Topics: Aldosterone; Angiotensin II; Aorta, Thoracic; Cell Movement; Cells, Cultured; Drug Synergism; Humans | 2015 |
[24-hour systolic wave increment index monitoring in patients with low-renin arterial hypertension].
Topics: Adult; Aldosterone; Arteries; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhyth | 2014 |
Should aldosterone suppression tests be conducted during a particular phase of the menstrual cycle, and, if so, which phase? Results of a preliminary study.
Topics: Adult; Aldosterone; Chromatography, High Pressure Liquid; Diagnostic Techniques, Endocrine; Estradio | 2015 |
Aldosterone Levels, Aortic Stiffness, and Wave Reflection in Essential Hypertensive Patients.
Topics: Adult; Aldosterone; Biomarkers; Female; Humans; Hypertension; Male; Middle Aged; Predictive Value of | 2015 |
Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; A | 2014 |
Plasma aldosterone and its relationship with left ventricular mass in hypertensive patients with early-stage chronic kidney disease.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Creatinine; Female; Humans; Hypertension; Hypertrophy, Lef | 2015 |
Effect of aldosterone-producing adenoma on endothelial function and Rho-associated kinase activity in patients with primary aldosteronism.
Topics: Adenoma; Adult; Aldosterone; Blood Pressure; Endothelium, Vascular; Female; Follow-Up Studies; Human | 2015 |
Expression and functional role of the prorenin receptor in the human adrenocortical zona glomerulosa and in primary aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aldosterone; Animals; Case-Control Studies | 2015 |
Iron restriction inhibits renal injury in aldosterone/salt-induced hypertensive mice.
Topics: Aldosterone; Animals; Hypertension; Iron, Dietary; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; | 2015 |
Primary aldosteronism and its various clinical scenarios.
Topics: Adult; Aged; Aldosterone; Cardiovascular Diseases; Female; Humans; Hyperaldosteronism; Hypertension; | 2015 |
Importance of contralateral aldosterone suppression during adrenal vein sampling in the subtype evaluation of primary aldosteronism.
Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Retrospective Stud | 2015 |
Unadjusted Plasma Renin Activity as a "First-Look" Test to Decide Upon Further Investigations for Primary Aldosteronism.
Topics: Adult; Aldosterone; Antihypertensive Agents; Body Mass Index; Female; Humans; Hyperaldosteronism; Hy | 2015 |
Plasma aldosterone concentration is positively associated with pulse pressure in patients with primary hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Logistic Models; Male; Middle Aged | 2015 |
Aldosterone and abnormal left ventricular geometry in chronic kidney disease.
Topics: Aldosterone; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Renal Insufficiency, | 2015 |
Plasma aldosterone and left ventricular diastolic function in treatment-naïve patients with hypertension: tissue-Doppler imaging study.
Topics: Adult; Aldosterone; Analysis of Variance; Case-Control Studies; Chi-Square Distribution; Diastole; E | 2015 |
Reliability of a Bayesian network to predict an elevated aldosterone-to-renin ratio.
Topics: Adult; Aldosterone; Bayes Theorem; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Ag | 2015 |
Global- and renal-specific sympathoinhibition in aldosterone hypertension.
Topics: Aldosterone; Analysis of Variance; Animals; Baroreflex; Blood Pressure; Disease Models, Animal; Dogs | 2015 |
Impact of global versus renal-specific sympathoinhibition in aldosterone-induced hypertension: implications for medical device-based treatment of resistant hypertension.
Topics: Aldosterone; Animals; Baroreflex; Hypertension; Male; Norepinephrine; Renin-Angiotensin System | 2015 |
Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism.
Topics: Adolescent; Adult; Age of Onset; Aldosterone; Amino Acid Sequence; Calcium; Calcium Channels, T-Type | 2015 |
Cost-Effectiveness of Therapeutic Drug Monitoring in Diagnosing Primary Aldosteronism in Patients With Resistant Hypertension.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Cost-Benefit Analysis; | 2015 |
Stress-induced Aldosterone Hyper-Secretion in a Substantial Subset of Patients With Essential Hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Case-Control Studies; Cy | 2015 |
Mineralocorticoid exposure and receptor activity modulate microvascular endothelial function in African Americans with and without hypertension.
Topics: Adult; Aldosterone; Black or African American; Blood Pressure; Endothelium, Vascular; Female; Humans | 2015 |
Neutrophil Gelatinase-Associated Lipocalin, a Novel Mineralocorticoid Biotarget, Mediates Vascular Profibrotic Effects of Mineralocorticoids.
Topics: Acute-Phase Proteins; Aldosterone; Animals; Aorta; Cardiomyopathy, Hypertrophic; Cells, Cultured; Cy | 2015 |
[The inversion of concepts about biological role of system rennin-angiotensin II- aldosterone and functions of arterial tension as a metabolism regulator].
Topics: Aldosterone; Angiotensin II; Arterial Pressure; Arteries; Chymosin; Essential Hypertension; Humans; | 2015 |
Obstructive Sleep Apnea Using Watch-PAT 200 Is Independently Associated With an Increase in Morning Blood Pressure Surge in Never-Treated Hypertensive Patients.
Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Ambulat | 2015 |
Changes in Renal Function and Oxidative Status Associated with the Hypotensive Effects of Oleanolic Acid and Related Synthetic Derivatives in Experimental Animals.
Topics: Aldosterone; Animals; Antihypertensive Agents; Antioxidants; Arginine Vasopressin; Blood Pressure; G | 2015 |
Association of Mineralocorticoid Receptor Polymorphism I180V With Left Ventricular Hypertrophy in Resistant Hypertension.
Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hypertension; Hypertrophy, Left Ventric | 2016 |
Effect of postural changes on aldosterone to plasma renin ratio in patients with suspected secondary hypertension.
Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Posture; Prospecti | 2015 |
Pharmacological profile of CS-3150, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist.
Topics: Administration, Oral; Adrenalectomy; Aldosterone; Animals; Antihypertensive Agents; Binding, Competi | 2015 |
Prevalence of Liddle Syndrome Among Young Hypertension Patients of Undetermined Cause in a Chinese Population.
Topics: Adult; Aldosterone; China; Diagnostic Errors; Essential Hypertension; Female; Humans; Hypertension; | 2015 |
Circulating tissue inhibitor of matrix metalloproteinase-1 is associated with aldosterone-induced diastolic dysfunction.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Diastole; Echoc | 2015 |
A renin-ssance in primary aldosteronism testing: obstacles and opportunities for screening, diagnosis, and management.
Topics: Aldosterone; Calcium Channels, L-Type; Fludrocortisone; G Protein-Coupled Inwardly-Rectifying Potass | 2015 |
Association of Post-Saline Load Plasma Aldosterone Levels With Left Ventricular Hypertrophy in Primary Hypertension.
Topics: Adult; Aldosterone; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; I | 2016 |
Maternal and Fetal Outcomes in Preeclampsia: Interrelations Between Insulin Resistance, Aldosterone, Metabolic Syndrome, and Polycystic Ovary Syndrome.
Topics: Aldosterone; Female; Humans; Hypertension; Insulin; Insulin Resistance; Metabolic Syndrome; Polycyst | 2015 |
Screening for primary aldosteronism in an argentinian population: a multicenter prospective study.
Topics: Adolescent; Adult; Aged; Aldosterone; Argentina; Female; Humans; Hyperaldosteronism; Hypertension; M | 2015 |
Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension.
Topics: Aldosterone; Anesthesia; Angiotensin II; Animals; Blood Pressure; Electrolytes; Hypertension; Intest | 2015 |
Primary Aldosteronism: Seismic Shifts.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Stress, Psychological | 2015 |
[IMPACT OF LONG-TERM ADAPTATION TO COLD ON THE STATE OF CARDIOVASCULAR SYSTEM].
Topics: Acclimatization; Adaptation, Physiological; Aldosterone; Angiotensin II; Animals; Arctic Regions; Ca | 2015 |
[Primary aldosteronism].
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Algorithms; Antihypert | 2015 |
β-Blocker withdrawal is preferable for accurate interpretation of the aldosterone-renin ratio in chronically treated hypertension.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Aged; Aldosterone; Angiotensin | 2016 |
Clinical validation for the aldosterone-to-renin ratio and aldosterone suppression testing using simultaneous fully automated chemiluminescence immunoassays.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Essential Hypertension; Female; Humans; | 2015 |
Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; beta Catenin; Female; Humans; Hyperaldosteroni | 2015 |
Lipophilic Statins and Aldosterone Secretion: A Bridge Too Far?
Topics: Adrenal Glands; Aldosterone; Animals; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors | 2015 |
Depressor effect of chymase inhibitor in mice with high salt-induced moderate hypertension.
Topics: Albuminuria; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Conve | 2015 |
Mineralocorticoid Receptor Antagonism for Cardiovascular Protection in End-Stage Renal Disease: New Data But the Controversy Continues.
Topics: Aldosterone; Humans; Hypertension; Kidney Failure, Chronic; Mineralocorticoid Receptor Antagonists; | 2016 |
Blood pressure changes after catheter-based renal denervation are related to reductions in total peripheral resistance.
Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; C | 2015 |
Normoaldosteronemic aldosterone-producing adenoma: immunochemical characterization and diagnostic implications.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Cytochrome P-45 | 2015 |
Discovery of N-[5-(6-Chloro-3-cyano-1-methyl-1H-indol-2-yl)-pyridin-3-ylmethyl]-ethanesulfonamide, a Cortisol-Sparing CYP11B2 Inhibitor that Lowers Aldosterone in Human Subjects.
Topics: Aldosterone; Animals; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Halogenation; Haplorhini; Humans; | 2015 |
Sodium interference in the determination of urinary aldosterone.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Reproducibility of Results; Sodi | 2016 |
Sodium Infusion Test for Diagnosis of Primary Aldosteronism in Chinese Population.
Topics: Adult; Aged; Aldosterone; Area Under Curve; Asian People; Blood Pressure; Female; Humans; Hyperaldos | 2016 |
Factors affecting parathyroid hormone levels in different types of primary aldosteronism.
Topics: Adenoma; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adult; Aldosterone; Calcium; Essential Hype | 2016 |
Inducible Knock-Down of the Mineralocorticoid Receptor in Mice Disturbs Regulation of the Renin-Angiotensin-Aldosterone System and Attenuates Heart Failure Induced by Pressure Overload.
Topics: Aldosterone; Animals; Collagen; Disease Models, Animal; Echocardiography; Electrolytes; Fibrosis; Ge | 2015 |
Role of brain aldosterone and mineralocorticoid receptors in aldosterone-salt hypertension in rats.
Topics: Aldosterone; Animals; Arterial Pressure; Corticosterone; Cytochrome P-450 CYP11B2; Drinking Behavior | 2016 |
Assessment of the Quantitative Value Usefulness of the Aldosterone-Renin Ratio (ARR) for Primary Aldosteronism (AQUARR) Study.
Topics: Adenoma; Aldosterone; Biomarkers; Databases, Factual; Humans; Hyperaldosteronism; Hypertension; Pred | 2016 |
Aldosterone Predicts Cardiovascular, Renal, and Metabolic Disease in the General Community: A 4-Year Follow-Up.
Topics: Aged; Aldosterone; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Echocardiography; | 2015 |
Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue.
Topics: Adipocytes, Brown; Adipocytes, White; Adipose Tissue, Brown; Adipose Tissue, White; Aldosterone; Ani | 2016 |
Eplerenone improves carotid intima-media thickness (IMT) in patients with primary aldosteronism.
Topics: Adrenalectomy; Adult; Aged; Aldosterone; Atherosclerosis; Biomarkers; Carotid Intima-Media Thickness | 2016 |
Association Between Pituitary-Adrenal Axis Dominance Over the Renin-Angiotensin-Aldosterone System and Hypertension.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Cross-Sectional Studies; Female; Humans; Hype | 2016 |
[Evaluation of the ratio of plasma aldosterone to rennin concentration measured by an automated chemiluminescent immunoassay in screening for primary aldosteronism].
Topics: Aldosterone; Area Under Curve; Case-Control Studies; Chymosin; Essential Hypertension; Humans; Hyper | 2016 |
Prospective validation of an automated chemiluminescence-based assay of renin and aldosterone for the work-up of arterial hypertension.
Topics: Adult; Aldosterone; Automation; Female; Humans; Hypertension; Luminescence; Male; Middle Aged; Prosp | 2016 |
Alteration of amiloride-sensitive salt taste nerve responses in aldosterone/NaCl-induced hypertensive rats.
Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Body Weight; Chorda Tympani Nerve; Epithelial Sodiu | 2016 |
Prevalence of Malignancies in Patients With Primary Aldosteronism.
Topics: Adult; Aged; Aldosterone; Biomarkers, Tumor; Blood Pressure; Case-Control Studies; Female; Germany; | 2016 |
A cross-sectional study of the effects of β-blocker therapy on the interpretation of the aldosterone/renin ratio: can dosing regimen predict effect?
Topics: Adrenergic beta-Antagonists; Aged; Aldosterone; Antihypertensive Agents; Cross-Sectional Studies; Di | 2016 |
[Clinical diagnosis and treatment of adrenocortical adenoma in patients aged 60 years or above].
Topics: Adrenocortical Adenoma; Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Middle Aged; Progn | 2016 |
The Aldosterone Renin Ratio (ARR) APP as Tool to Enhance the Detection Rate of Primary Aldosteronism.
Topics: Aldosterone; Biomarkers; Diagnosis, Computer-Assisted; Discriminant Analysis; Humans; Hyperaldostero | 2016 |
Urinary sodium excretion predicts blood pressure response to spironolactone in patients with resistant hypertension independent of aldosterone status.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Middle Age | 2016 |
Decrease in serum potassium levels post saline suppression test in primary aldosteronism: an under-recognised phenomenon?
Topics: Aldosterone; Diagnostic Tests, Routine; Female; Humans; Hyperaldosteronism; Hypertension; Potassium; | 2016 |
Common Polymorphisms at the CYP17A1 Locus Associate With Steroid Phenotype: Support for Blood Pressure Genome-Wide Association Study Signals at This Locus.
Topics: Adult; Aged; Aldosterone; Alleles; Blood Pressure; Cohort Studies; Female; Gene Expression Regulatio | 2016 |
The story of spironolactones from 1957 to now: from sodium balance to inflammation.
Topics: Aldosterone; History, 20th Century; History, 21st Century; Hypertension; Inflammation; Mineralocorti | 2016 |
Activation of cardiac renin-angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder.
Topics: Aldosterone; Animals; Ataxia Telangiectasia Mutated Proteins; Cardiovascular Diseases; Contraceptive | 2017 |
Aldosterone-to-Renin Ratio Is Associated With Reduced 24-Hour Heart Rate Variability and QTc Prolongation in Hypertensive Patients.
Topics: Adult; Aged; Aldosterone; Austria; Autonomic Nervous System Diseases; Blood Pressure; Blood Pressure | 2016 |
Leptin Induces Hypertension and Endothelial Dysfunction via Aldosterone-Dependent Mechanisms in Obese Female Mice.
Topics: Aldosterone; Analysis of Variance; Animals; Cardiovascular Diseases; Disease Models, Animal; Endothe | 2016 |
Association of Circulating Renin and Aldosterone With Osteocalcin and Bone Mineral Density in African Ancestry Families.
Topics: Adult; Age Factors; Aged; Aldosterone; Anthropometry; Biomarkers; Black People; Body Mass Index; Bon | 2016 |
Adrenal Venous Sampling in Patients With Positive Screening but Negative Confirmatory Testing for Primary Aldosteronism.
Topics: Adrenal Glands; Age Factors; Aged; Aldosterone; Cohort Studies; Cosyntropin; Female; Humans; Hyperal | 2016 |
An App for the Diagnosis of Primary Aldosteronism.
Topics: Aldosterone; Arterial Pressure; Biomarkers; Computers, Handheld; Humans; Hyperaldosteronism; Hyperte | 2016 |
SFE/SFHTA/AFCE consensus on primary aldosteronism, part 4: Subtype diagnosis.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adult; Age Factors; Aldosterone; France; Humans; Hydrocorti | 2016 |
Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors.
Topics: Aldosterone; Analysis of Variance; Animals; Disease Models, Animal; Endothelium, Vascular; Hypertens | 2016 |
A new highly sensitive and specific overnight combined screening and diagnostic test for primary aldosteronism.
Topics: Adult; Aged; Aldosterone; Captopril; Dexamethasone; Diagnostic Tests, Routine; Female; Humans; Hyper | 2016 |
Enhanced Soluble Serum CD40L and Serum P-Selectin Levels in Primary Aldosteronism.
Topics: Adrenocortical Adenoma; Aldosterone; Anthropometry; CD40 Ligand; Female; Humans; Hyperaldosteronism; | 2016 |
Alterations in plasma membrane promote overexpression and increase of sodium influx through epithelial sodium channel in hypertensive platelets.
Topics: Aged; Aldosterone; Blood Platelets; Case-Control Studies; Caveolin 1; Caveolins; Dystroglycans; Epit | 2016 |
Letter by Campbell Regarding Article, "Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects".
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Diabetes Mellitus; Humans; Hydroxymethylglutaryl-CoA Re | 2016 |
Response to Letter Regarding Article, "Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects".
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Diabetes Mellitus; Humans; Hydroxymethylglutaryl-CoA Re | 2016 |
2016 Endocrine Society guidelines update for the diagnosis of primary aldosteronism: are the proposed aldosterone-to-renin ratio cut-off values relevant in the era of fully automated immunoassays?
Topics: Aldosterone; Automation, Laboratory; Endocrinology; Humans; Hyperaldosteronism; Hypertension; Immuno | 2016 |
Mineralocorticoid and angiotensin II type 1 receptors in the subfornical organ mediate angiotensin II - induced hypothalamic reactive oxygen species and hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dependovirus; Gene Knockdown Techniques; Genet | 2016 |
In Liddle Syndrome, Epithelial Sodium Channel Is Hyperactive Mainly in the Early Part of the Aldosterone-Sensitive Distal Nephron.
Topics: Aldosterone; Animals; Disease Models, Animal; Epithelial Sodium Channels; Hypertension; Kidney Tubul | 2016 |
SFE/SFHTA/AFCE Consensus on Primary Aldosteronism, part 2: First diagnostic steps.
Topics: Age Factors; Aldosterone; Antihypertensive Agents; Blood Specimen Collection; Female; Humans; Hypera | 2016 |
[Renin and aldosterone determinations in hypertensive patients].
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Biomarkers; Female; Humans; Hyperaldosteronism; Hyperte | 2016 |
Causes of secondary hypertension in the young population: A monocentric study.
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Aortic Coarctation; Biomarkers; Blood Pressure Monitori | 2016 |
Secondary hypertension in adults.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Aortic Coarctation; Blood Pressure; Glomerulo | 2016 |
Clinical Outcomes following Percutaneous Radiofrequency Ablation of Unilateral Aldosterone-Producing Adenoma: Comparison with Adrenalectomy.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Antihypertensive Agents; Bioma | 2016 |
Angiotensin 1-7 Is a Negative Modulator of Aldosterone Secretion In Vitro and In Vivo.
Topics: Aldosterone; Angiotensin I; Animals; Antihypertensive Agents; Fluorescent Antibody Technique; Humans | 2016 |
[An evaluation of plasma aldosterone-to-active-renin ratio in different postures in combination with aldosterone concentration in the diagnosis of aldosteronoma].
Topics: Aldosterone; Asian People; China; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension; | 2016 |
Functional characterization of two novel germline mutations of the KCNJ5 gene in hypertensive patients without primary aldosteronism but with ACTH-dependent aldosterone hypersecretion.
Topics: Adrenocorticotropic Hormone; Aldosterone; Cytochrome P-450 CYP11B2; Electrophysiological Phenomena; | 2016 |
KCNK3 Variants Are Associated With Hyperaldosteronism and Hypertension.
Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; California; Ethnicity; Female; Genetic Pr | 2016 |
Cardiac Structure and Function in Hyperaldosteronism.
Topics: Aldosterone; Heart; Humans; Hyperaldosteronism; Hypertension | 2016 |
SFE/SFHTA/AFCE primary aldosteronism consensus: Introduction and handbook.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Calcium Channel Blockers; France; Humans | 2016 |
Parathyroid hormone, aldosterone-to-renin ratio and fibroblast growth factor-23 as determinants of nocturnal blood pressure in primary hyperparathyroidism: the eplerenone in primary hyperparathyroidism trial.
Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; C | 2016 |
Prevalence, Neurohormonal Correlates, and Prognosis of Heart Failure Stages in the Community.
Topics: Adult; Aged; Aldosterone; C-Reactive Protein; Coronary Artery Disease; Diabetes Mellitus; Female; He | 2016 |
ARAs to the RESCUE.
Topics: Aldosterone; Eplerenone; Gynecomastia; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Meta-A | 2016 |
Dietary Sodium Restriction Increases the Risk of Misinterpreting Mild Cases of Primary Aldosteronism.
Topics: Adult; Aldosterone; Algorithms; Cohort Studies; Diagnostic Errors; Diet, Sodium-Restricted; Down-Reg | 2016 |
Aldosterone-Renin Ratio and Side-Selective Renal Perfusion in Essential Hypertension.
Topics: Aldosterone; Blood Pressure; Essential Hypertension; Humans; Hypertension; Kidney; Renin; Renin-Angi | 2016 |
Endogenous ouabain and aldosterone are coelevated in the circulation of patients with essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Essential Hypertension; Female; Humans; Hyperaldosteronism; Hype | 2016 |
Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension.
Topics: Adiponectin; Adolescent; Aldosterone; Blood Pressure; Body Mass Index; C-Reactive Protein; Child; Ch | 2016 |
Radiofrequency ablation compared with laparoscopic adrenalectomy for aldosterone-producing adenoma.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aftercare; Aged; Aged, 80 and ov | 2016 |
On the top of ARB N/L type Ca channel blocker leads to less elevation of aldosterone.
Topics: Aged; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blo | 2016 |
Body Mass Index Predicts 24-Hour Urinary Aldosterone Levels in Patients With Resistant Hypertension.
Topics: Adult; Age Factors; Aged; Aldosterone; Blood Pressure Determination; Body Mass Index; Comorbidity; C | 2016 |
Letter by Zhou and Zhou Regarding Article, "Hypertension: Renin-Angiotensin-Aldosterone System Alterations".
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin-Angiotensin System | 2016 |
Response by Danser and van den Meiracker to Letter by Zhou and Zhou Regarding Article, "Hypertension: Renin-Angiotensin-Aldosterone System Alterations".
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin-Angiotensin System | 2016 |
The Clinical Value of Salivary Aldosterone in Diagnosis and Follow-Up of Primary Aldosteronism.
Topics: Adrenalectomy; Aged; Aldosterone; Case-Control Studies; Circadian Rhythm; Eplerenone; Female; Follow | 2016 |
Primary aldosteronism in patients with acute stroke: prevalence and diagnosis during initial hospitalization.
Topics: Aged; Aldosterone; Comorbidity; Female; Hospitalization; Humans; Hyperaldosteronism; Hypertension; J | 2016 |
Cholecalciferol treatment downregulates renin-angiotensin system and improves endothelial function in essential hypertensive patients with hypovitaminosid D.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Cardiovascular Diseases; Cholecalciferol; Endoth | 2016 |
Renal denervation attenuates aldosterone expression and associated cardiovascular pathophysiology in angiotensin II-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Calcitonin Gene-Related Peptide; Cell Line, Tumor; Denervation | 2016 |
Acute Vasodilation Caused by Different Strategies of Renal Sympathetic Denervation for Right and Left Renal Arteries.
Topics: Aldosterone; Biomarkers; Blood Pressure; Catheter Ablation; Cross-Sectional Studies; Humans; Hyperte | 2017 |
PRIMARY ALDOSTERONISM IN THE PRIMARY CARE CLINIC: RIFE OR RARE?
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Primary Health Care; Renin | 2016 |
Some Considerations About Primary Aldosteronism and Its Follow-Up.
Topics: Aldosterone; Follow-Up Studies; Humans; Hyperaldosteronism; Hypertension; Renin | 2016 |
Increased urinary excretion of the epithelial Na channel activator prostasin in patients with primary aldosteronism.
Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Epithelial Sodium Channels; Essential Hypertension; | 2017 |
Primary aldosteronism as a public health issue.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Public Health | 2016 |
PREVELENCE OF PRIMARY ALDOSTERONISM IN AN URBAN HYPERTENSIVE POPULATION.
Topics: Adult; Aged; Aldosterone; Comorbidity; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middl | 2016 |
Liddle syndrome: clinical and genetic profiles.
Topics: Adolescent; Adult; Aldosterone; Alleles; Child; China; Creatinine; Epithelial Sodium Channel Blocker | 2017 |
Whole-exome sequencing reveals an inherited R566X mutation of the epithelial sodium channel β-subunit in a case of early-onset phenotype of Liddle syndrome.
Topics: Adult; Aldosterone; Alleles; Amiloride; Child, Preschool; Epithelial Sodium Channels; Exome; Exome S | 2016 |
High-sensitive C-reactive protein in primary aldosteronism.
Topics: Aldosterone; C-Reactive Protein; Humans; Hyperaldosteronism; Hypertension | 2017 |
Role of adrenocorticotropic hormone in essential hypertension and primary aldosteronism.
Topics: Adenoma; Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Essential Hypertension; Humans; H | 2017 |
Plasma adrenocorticotropic hormone but not aldosterone is correlated with blood pressure in patients with aldosterone-producing adenomas.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Blood Pressure; Essential Hypertensi | 2017 |
High Frequency of Variants of Candidate Genes in Black Africans with Low Renin-Resistant Hypertension.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Black People; Blood Pressure; Cytochrome P-450 | 2017 |
Novel Approach to Establishing an Aldosterone: Renin Ratio Cutoff for Primary Aldosteronism.
Topics: Alberta; Aldosterone; Biomarkers; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Age | 2017 |
Positive association between KCNJ5 rs2604204 (A/C) polymorphism and plasma aldosterone levels, but also plasma renin and angiotensin I and II levels, in newly diagnosed hypertensive Chinese: a case-control study.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure Monitoring, Ambulatory; Case-Contr | 2017 |
Assessment of the Aldosteronona resolution score as a predictive resolution score of hypertension after adrenalectomy for aldosteronoma in French patients.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aged, 80 and over; Aldoste | 2017 |
Plasma aldosterone level within the normal range is less associated with cardiovascular and cerebrovascular risk in primary aldosteronism.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Cardiovascular Diseases; Cross-Sectional Studies; Essentia | 2017 |
Changes in the expression of α
Topics: Adult; Aldosterone; Animals; Blood Pressure; Enzyme Inhibitors; Female; Homocysteine; Humans; Hypert | 2017 |
Early treatment with losartan effectively ameliorates hypertension and improves vascular remodeling and function in a prehypertensive rat model.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Expression Regula | 2017 |
Clinical outcomes following unilateral adrenalectomy in patients with primary aldosteronism.
Topics: Adrenalectomy; Adult; Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Blood Pressure; | 2017 |
Increased Aldosterone Release During Head-Up Tilt in Early Primary Hypertension.
Topics: Adult; Age Factors; Aldosterone; Angiotensin II; Biomarkers; Blood Pressure; Case-Control Studies; H | 2017 |
The importance of genetic counseling and genetic screening: a case report of a 16-year-old boy with resistant hypertension and severe hypokalemia.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; 46, XX Disorders of Sex Development; Adolescent; Adrenal Glan | 2017 |
Serum uric acid is not independently associated with plasma renin activity and plasma aldosterone in hypertensive adults.
Topics: Adiposity; Adult; Age Factors; Aldosterone; Biomarkers; Blood Pressure; Chi-Square Distribution; Cro | 2017 |
Primary Aldosteronism or Not Primary Aldosteronism: Is This Now the Question in Normotension?
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension | 2017 |
A Late Diagnosis of Primary Aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Antihypertensiv | 2017 |
Characterization of resistant hypertension: association between resistant hypertension, aldosterone, and persistent intravascular volume expansion.
Topics: Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Case-Control Studies; Drug Resistan | 2008 |
Increased carotid intima-media thickness in hypertensive patients with a high aldosterone/plasma renin activity ratio and elevated aldosterone plasma concentration.
Topics: Aldosterone; Carotid Arteries; Humans; Hypertension; Renin; Tunica Intima; Tunica Media; Ultrasonogr | 2008 |
Plasma aldosterone and its relationships with left ventricular mass in essential hypertensive patients with the metabolic syndrome.
Topics: Adult; Aldosterone; Blood Pressure; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Lef | 2008 |
Primary hyperaldosteronism due to adrenal microadenoma: a curable cause of refractory hypertension.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Antihypertensive Agents; Blood Pressu | 2008 |
Menopause not aldosterone-to-renin ratio predicts blood pressure response to a mineralocorticoid receptor antagonist in primary care hypertensive patients.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aldosterone; Blood Pressure; Canrenoic Acid; Female; Huma | 2008 |
Response to genetic manipulations of liver angiotensinogen in the physiological range.
Topics: Aldosterone; Angiotensinogen; Animals; Gene Dosage; Genetic Engineering; Hypertension; Liver; Male; | 2008 |
Exaggerated blood pressure response to exercise is associated with augmented rise of angiotensin II during exercise.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Bicycling; Blood Pressure; Case-Control Studies; Catechola | 2008 |
Effects of aldosterone on the heart: beyond systemic hemodynamics?
Topics: Aldosterone; Animals; Blood Pressure; Heart; Humans; Hypertension; Hypertrophy, Left Ventricular | 2008 |
Inappropriate left ventricular mass in patients with primary aldosteronism.
Topics: Adaptation, Physiological; Adult; Aged; Aldosterone; Echocardiography; Female; Humans; Hyperaldoster | 2008 |
A patient with a juxtaglomerular cell tumor with histological vascular invasion.
Topics: Aldosterone; Blood Vessels; Female; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney Neoplasm | 2008 |
Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet.
Topics: Adiposity; Aldosterone; Angiotensins; Animals; Blood Glucose; Blood Pressure; Cell Line; Diet; Dieta | 2008 |
Blood pressure outcome of adrenalectomy in patients with primary hyperaldosteronism with or without unilateral adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Female; Follow- | 2008 |
Effect of weight loss through laparoscopic gastric banding on blood pressure, plasma renin activity and aldosterone levels in morbid obesity.
Topics: Adult; Aldosterone; Bariatric Surgery; Blood Glucose; Blood Pressure; Down-Regulation; Female; Human | 2009 |
[Possible pathogenetic role of 11 beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) gene polymorphisms in arterial hypertension].
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adrenocorticotropic Hormone; Adult; Aldosterone; Case-C | 2008 |
Polymorphism of the aldosterone synthase gene is not associated with progression of diabetic nephropathy, but associated with hypertension in type 2 diabetic patients.
Topics: Adult; Aged; Aldosterone; Cytochrome P-450 CYP11B2; Diabetes Mellitus, Type 2; Diabetic Nephropathie | 2008 |
Screening for primary aldosteronism in a cohort of Brazilian patients with resistant hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aged; Aldosterone; Brazil; Cross-Sectional Studies | 2008 |
[Primary hyperaldosteronism in hypertension].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 2008 |
Primary aldosteronism in newly diagnosed hypertensive patients.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Predictive Value of Tests; Reference Values; | 2008 |
The cutoff value of aldosterone-to-renin ratio for the diagnosis of primary aldosteronism in patients taking antihypertensive medicine.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Aged; Aldosterone; Antihypertensi | 2008 |
[Role of antialdosteronics in the treatment of refractory hypertension].
Topics: Aldosterone; Clinical Trials as Topic; Diuretics; Drug Resistance; Humans; Hypertension; Mineralocor | 2008 |
The blood pressure variability, arterial elasticity and humoral factors in subjects with family history of hypertension.
Topics: Adult; Aldosterone; Arteries; Blood Pressure; Catecholamines; Elasticity; Female; Humans; Hypertensi | 2008 |
Relationship of plasma renin with a prothrombotic state in hypertension: relevance for organ damage.
Topics: Adult; Aldosterone; Algorithms; Analysis of Variance; Biomarkers; Cerebrovascular Disorders; Cross-S | 2008 |
Hypertension-induced renal fibrosis and spironolactone response vary by rat strain and mineralocorticoid receptor gene expression.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Collagen Type I; Fibrosis; Gene Expression Regula | 2008 |
Collectrin is involved in the development of salt-sensitive hypertension by facilitating the membrane trafficking of apical membrane proteins via interaction with soluble N-ethylmaleiamide-sensitive factor attachment protein receptor complex.
Topics: Aldosterone; Animals; Aquaporin 2; Blood Pressure; Cell Line; Collectins; Epithelial Sodium Channels | 2008 |
Angiotensinogen gene haplotypes in hypertension.
Topics: Aldosterone; Alleles; Angiotensinogen; Haplotypes; Humans; Hypertension; Polymorphism, Single Nucleo | 2008 |
Actions of aldosterone in the cardiovascular system: the good, the bad, and the ugly?
Topics: Aldosterone; Angiotensin II; Blood Pressure; Cardiovascular System; ErbB Receptors; Homeostasis; Hyp | 2009 |
"Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim | 2009 |
Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study.
Topics: Aldosterone; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; C-Reactive Protein; Cross-Sectio | 2009 |
Mechanisms in the PVN mediating local and central sodium-induced hypertension in Wistar rats.
Topics: Aldosterone; Amiloride; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic | 2009 |
Mineralocorticoid receptor antagonism attenuates vascular apoptosis and injury via rescuing protein kinase B activation.
Topics: Aldosterone; Animals; Aorta, Thoracic; Apoptosis; bcl-Associated Death Protein; Blood Pressure; Cyto | 2009 |
Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt-induced hypertension in Dahl salt-sensitive rats.
Topics: Aldosterone; Animals; Blood Pressure; Corticosterone; Cytochrome P-450 CYP11B2; Disease Models, Anim | 2009 |
Expression of NAD(P)H oxidase subunits and their contribution to cardiovascular damage in aldosterone/salt-induced hypertensive rat.
Topics: Acetophenones; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agen | 2008 |
Endocrine rhythms and expression of selected genes in the brain, stellate ganglia, and adrenals of hypertensive TGR rats.
Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Brain; Circadian Rhythm; Corticosterone; Dopam | 2008 |
Small tumor size as favorable prognostic factor after adrenalectomy in Conn's adenoma.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aged; Aldosterone; Blood Pressure; | 2009 |
Aldosterone and Cardiovascular Disease. Foreword.
Topics: Adrenalectomy; Aldosterone; Animals; Antihypertensive Agents; Cardiovascular Agents; Cardiovascular | 2009 |
Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured; Esters; Gabexate; Gu | 2009 |
Aldosterone and alterations of hypertension-related vascular function in African Americans.
Topics: Adolescent; Adult; Aldosterone; Anthropometry; Black or African American; Cardiac Output; Catecholam | 2009 |
Aldosterone levels and stroke incidence in essential hypertensive patients.
Topics: Aldosterone; Blood Pressure; Cross-Sectional Studies; Female; Follow-Up Studies; Greece; Humans; Hyp | 2010 |
Primary hyperaldosteronism in a domestic ferret with an adrenocortical adenoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Animals; Fatal Outcome; Female; Ferre | 2008 |
[Evaluation of selected endocrine parameters in smoking patients with arterial hypertension].
Topics: Aldosterone; Female; Humans; Hypertension; Insulin; Male; Middle Aged; Smoking | 2008 |
Primary aldosteronism with aldosterone-producing adenoma consisting of pure zona glomerulosa-type cells in a pregnant woman.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Estrogen Recept | 2009 |
Prevalence of primary hyperaldosteronism in a systemic arterial hypertension league.
Topics: Adrenal Glands; Aldosterone; Antihypertensive Agents; Fasting; Female; Humans; Hyperaldosteronism; H | 2009 |
Aldosterone and metabolic dysfunction: an unresolved issue.
Topics: Aldosterone; Animals; Dyslipidemias; Humans; Hyperaldosteronism; Hypertension; Hypokalemia | 2009 |
Trilostane, FAD286, and the role of aldosterone in the central regulation of blood pressure: focus on "Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt-induced hypertension in Dahl salt-sensitive rats".
Topics: 3-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Blood Pressure; Corticosterone; Cytochrome P- | 2009 |
Left ventricular hypertrophy and geometry in hypertensive patients with chronic kidney disease.
Topics: Aged; Aldosterone; Blood Pressure Determination; Case-Control Studies; Catecholamines; Chronic Disea | 2009 |
Blood pressure outcome of adrenalectomy in patients with primary hyperaldosteronism with or without unilateral adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Blood Pressure; | 2009 |
T allele of -344 C/T polymorphism in aldosterone synthase gene is not associated with resistant hypertension.
Topics: Adult; Aldosterone; Alleles; Blood Pressure; Carotid Arteries; Cytochrome P-450 CYP11B2; Drug Resist | 2009 |
Sex differences and central protective effect of 17beta-estradiol in the development of aldosterone/NaCl-induced hypertension.
Topics: Administration, Oral; Aldosterone; Animals; Blood Pressure; Body Weight; Brain; Disease Models, Anim | 2009 |
Medical management of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 2009 |
Hypertension, insulin resistance, and aldosterone: sex-specific relationships.
Topics: Adolescent; Adult; Age Factors; Aldosterone; Anthropometry; Black or African American; Blood Glucose | 2009 |
Aldosterone blockade by Spironolactone improves the hypertensive vascular hypertrophy and remodeling in angiotensin II overproducing transgenic mice.
Topics: Aldosterone; Angiotensin II; Animals; Female; Hyperplasia; Hypertension; Hypertrophy; Male; Mice; Mi | 2009 |
Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cytoc | 2009 |
Renal functional, not morphological, abnormalities account for salt sensitivity in Dahl rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cyclic GMP; Diastole; Dose-Response Relationsh | 2009 |
Swimming prevents vulnerable atherosclerotic plaque development in hypertensive 2-kidney, 1-clip mice by modulating angiotensin II type 1 receptor expression independently from hemodynamic changes.
Topics: Aldosterone; Animals; Apolipoproteins E; Atherosclerosis; Blood Pressure; Cholesterol; Citrate (si)- | 2009 |
Endothelial dysfunction is related to aldosterone excess and raised blood pressure.
Topics: Aged; Aldosterone; Endothelium, Vascular; Female; Humans; Hyperaldosteronism; Hypertension; Male; Mi | 2009 |
Programming of hypertension: associations of plasma aldosterone in adult men and women with birthweight, cortisol, and blood pressure.
Topics: Adrenocorticotropic Hormone; Age Factors; Aged; Aldosterone; Analysis of Variance; Birth Weight; Blo | 2009 |
Factors determining cardiovascular and renal outcomes after adrenalectomy in patients with aldosterone-producing adrenal adenoma.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Cardiovas | 2009 |
Long-term effects of surgical correction of adrenal hyperplasia and adenoma causing primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Analysis of Variance; | 2010 |
Hyperaldosteronism in an adolescent with Gardner's syndrome.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Female; Fibromatosis, Aggr | 2009 |
Aberrant ENaC activation in Dahl salt-sensitive rats.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Epithelial Sodium Channels; Hypertension; Kidney; | 2009 |
Aldosterone-producing adrenal cortical adenoma with oncocytic change and cytoplasmic eosinophilic globular inclusions.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aged; Aldosterone; Antihypertensive Agents; Female | 2009 |
Aldosterone, a vasculotoxic agent--novel functions for an old hormone.
Topics: Aldosterone; Blood Pressure; Blood Vessels; Humans; Hypertension; Receptors, Mineralocorticoid | 2009 |
Metabolic syndrome in primary aldosteronism and essential hypertension: relationship to adiponectin gene variants.
Topics: Adiponectin; Aldosterone; Biomarkers; Blood Glucose; Chi-Square Distribution; Cross-Sectional Studie | 2010 |
Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC.
Topics: Adenomatous Polyposis Coli Protein; Aldosterone; Animals; Blood Pressure; Blood Volume; Body Weight; | 2009 |
Aldosterone in clinical nephrology--old hormone, new questions.
Topics: Aldosterone; Eplerenone; Humans; Hypertension; Kidney Diseases; Mineralocorticoid Receptor Antagonis | 2009 |
Elevated aldosterone levels in patients with androgenetic alopecia.
Topics: Adult; Aldosterone; Alopecia; Case-Control Studies; Humans; Hypertension; Male; Middle Aged; Pilot P | 2009 |
Adrenal venous sampling for primary aldosteronism and clinical outcomes after unilateral adrenalectomy: a single-center experience.
Topics: Adrenalectomy; Adult; Aldosterone; Blood Pressure; Creatinine; Female; Humans; Hyperaldosteronism; H | 2009 |
Going with the Wnt? Focus on "Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC".
Topics: Adenomatous Polyposis Coli Protein; Aldosterone; Animals; Blood Pressure; Blood Volume; Glomerular F | 2009 |
Sodium chloride and aldosterone: harbingers of hypertension-related cardiovascular disease.
Topics: Aldosterone; Animals; Blood Pressure; Cardiovascular Diseases; Echocardiography; Humans; Hypertensio | 2009 |
Independent relations of left ventricular structure with the 24-hour urinary excretion of sodium and aldosterone.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Echocardiography; Female; H | 2009 |
Primary aldosteronism can alter peripheral levels of transforming growth factor beta and tumor necrosis factor alpha.
Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Inter | 2009 |
Atrial fibrillation in primary aldosteronism.
Topics: Adult; Aldosterone; Atrial Fibrillation; Female; Humans; Hyperaldosteronism; Hypertension; Hypertrop | 2009 |
Effects of fixed-dose isosorbide dinitrate/hydralazine on diastolic function and exercise capacity in hypertension-induced diastolic heart failure.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Cytokines; Diastole; Drug Therapy, | 2009 |
Association of kidney function with residual hypertension after treatment of aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Creatinine; Fe | 2009 |
[Normokalaemic primary aldosteronism due to an aldosterone-producing adrenal adenoma--Case 06/2009].
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Diagnosis, Diff | 2009 |
Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression.
Topics: Aldosterone; Animals; Antibodies, Monoclonal; Blood Pressure; Enzyme Inhibitors; Gene Expression; Hy | 2009 |
[Neurohumoral regulation of blood pressure in rheumatic patients].
Topics: Aldosterone; Blood Pressure; Catecholamines; Endothelins; Epinephrine; Humans; Hypertension; Kidney; | 2009 |
[Endocrine hypertension].
Topics: Adrenal Gland Neoplasms; Aldosterone; Cushing Syndrome; Humans; Hyperaldosteronism; Hypertension; Hy | 2009 |
Update in primary aldosteronism.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Amiloride; Antihypertensive Agents; Chromos | 2009 |
Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism.
Topics: Administration, Oral; Aldosterone; Animals; Cardiomegaly; Collagen Type I; Cytochrome P-450 CYP1A1; | 2009 |
Aldosterone contributes to blood pressure variance and to likelihood of hypertension in normal-weight and overweight African Americans.
Topics: Adult; Aldosterone; Black or African American; Blood Pressure; Body Mass Index; Cross-Sectional Stud | 2009 |
Dietary salt restriction activates mineralocorticoid receptor signaling in volume-overloaded heart failure.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Body Weight; Cell Size; Contraindications; Diet, So | 2009 |
The dual role of the kidney in primary aldosteronism: key determinant in rescue from volume expansion and persistence of hypertension.
Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hyperten | 2009 |
CYP11B2 gene haplotypes independently and in concurrence with aldosterone and aldosterone to renin ratio increase the risk of hypertension.
Topics: Adult; Aged; Aldosterone; Cytochrome P-450 CYP11B2; Genetic Predisposition to Disease; Haplotypes; H | 2010 |
[Correlations between heart rate variability, renin activity and plasma aldosteron concentration in chronic glomerulonephritis with intact function of the kidneys].
Topics: Adult; Aldosterone; Autonomic Nervous System; Cardiovascular System; Chronic Disease; Glomerulonephr | 2009 |
The role of aldosterone in mediating the dependence of angiotensin hypertension on IL-6.
Topics: Aldosterone; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; D | 2009 |
Familial and phenotypic associations of the aldosterone Renin ratio.
Topics: Adult; Aldosterone; Blood Pressure; Body Mass Index; Circadian Rhythm; Family; Female; Genotype; Hum | 2009 |
Aldosterone synthesis in the brain contributes to Dahl salt-sensitive rat hypertension.
Topics: Aldosterone; Animals; Brain; Cytochrome P-450 CYP11B2; Female; Hypertension; Male; Rats; Rats, Inbre | 2010 |
Clinical effects of eplerenone, a selective aldosterone blocker, in Japanese patients with essential hypertension.
Topics: Aged; Albuminuria; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; A | 2010 |
Some considerations about evolution of idiopathic primary aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Refer | 2009 |
Hypovolaemia-induced metabolic dysfunction, mediated in part by aldosterone and angiotensin.
Topics: Aldosterone; Angiotensins; Humans; Hypertension; Hypovolemia; Metabolic Syndrome; Renin-Angiotensin | 2009 |
Gender differences in angiotensin II and aldosterone secretion in patients with pressure overloaded systemic right ventricles are similar to those observed in systemic arterial hypertension.
Topics: Adolescent; Aldosterone; Angiotensin II; Biomarkers; Blood Pressure; Female; Humans; Hypertension; I | 2011 |
Hypertension and aldosterone levels in women with early-onset androgenetic alopecia.
Topics: Adult; Age Factors; Aldosterone; Alopecia; Biomarkers; Blood Pressure; Case-Control Studies; Female; | 2010 |
Nonalcoholic fatty liver disease in primary aldosteronism: a pilot study.
Topics: Adult; Aldosterone; Fatty Liver; Female; Homeostasis; Humans; Hyperaldosteronism; Hypertension; Hypo | 2010 |
Aldosterone and hypertension in African Americans.
Topics: Aldosterone; Black or African American; Humans; Hypertension; Renin | 2009 |
Inappropriately high circulating and intrarenal angiotensin II levels during dietary salt loading exacerbate hypertension in Cyp1a1-Ren-2 transgenic rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Creatinine; Cytochrome P-450 CYP1A1; Hypertens | 2010 |
Within-patient reproducibility of the aldosterone: renin ratio in primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldoste | 2010 |
Commentary.
Topics: Aldosterone; Dietary Supplements; Female; Glycyrrhiza; Glycyrrhizic Acid; Humans; Hypertension; Hypo | 2009 |
Too much of a good thing: a woman with hypertension and hypokalemia.
Topics: Aldosterone; Chronic Disease; Dietary Supplements; Female; Glycyrrhiza; Glycyrrhizic Acid; Humans; H | 2009 |
Commentary.
Topics: Aldosterone; Dietary Supplements; Female; Glycyrrhiza; Glycyrrhizic Acid; Humans; Hypertension; Hypo | 2009 |
Choice of diuretic therapy and reconsideration for aldosterone receptors blockers.
Topics: Aldosterone; Blood Pressure; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Humans; Hy | 2010 |
Effects of female sex hormones and contraceptive pill on the diagnostic work-up for primary aldosteronism.
Topics: Aldosterone; Comorbidity; Contraceptives, Oral; Estradiol; Female; Humans; Hyperaldosteronism; Hyper | 2010 |
Spironolactone for all hypertensive patients?
Topics: Aldosterone; Diuretics; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hypertension; Practic | 2010 |
Vasculoprotective effect of cilostazol in aldosterone-induced hypertensive rats.
Topics: Aldosterone; Animals; Aorta; Atherosclerosis; Blood Pressure; Chemokine CCL2; Cilostazol; Disease Mo | 2010 |
Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6.
Topics: Aldosterone; Animals; Circadian Rhythm; Cryptochromes; Gene Expression Regulation; Humans; Hypertens | 2010 |
Common genetic variations of the renin-angiotensin-aldosterone system and response to acute angiotensin I-converting enzyme inhibition in essential hypertension.
Topics: Adult; Aldosterone; Alleles; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Antihyperten | 2010 |
Hypertension finds a new rhythm.
Topics: Aldosterone; Animals; Circadian Rhythm; Cryptochromes; Hypertension; Mice; Progesterone Reductase; S | 2010 |
Plasma aldosterone and glomerular filtration in hypertensive patients with preserved renal function.
Topics: Aldosterone; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Pr | 2010 |
Improved quality of life, blood pressure, and biochemical status following laparoscopic adrenalectomy for unilateral primary aldosteronism.
Topics: Adrenalectomy; Adult; Aged; Aldosterone; Blood Pressure; Female; Health Status; Humans; Hyperaldoste | 2010 |
Are plasma renin activity and aldosterone levels useful as a screening test to differentiate between unilateral and bilateral renal artery stenosis in hypertensive patients?
Topics: Adult; Aldosterone; Angioplasty, Balloon; Female; Humans; Hypertension; Male; Middle Aged; Renal Art | 2010 |
[Clinical characteristics of five elderly patients with severe hypokalemia induced by glycyrrhizin derivatives].
Topics: Aged; Aged, 80 and over; Aldosterone; Alkalosis; Anti-Inflammatory Agents; Drugs, Chinese Herbal; Fe | 2010 |
Adipokines and cardiometabolic profile in primary hyperaldosteronism.
Topics: Adenoma; Adiponectin; Adult; Aged; Aldosterone; Biomarkers; Blood Glucose; Blood Pressure; C-Reactiv | 2010 |
[Effect of electroacupuncture of different acupoints on blood pressure, plasma angiotensin II, aldosterone and atrial natriuretic peptide in spontaneous hypertension rats].
Topics: Acupuncture Points; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; | 2009 |
Salivary aldosterone as a diagnostic aid in primary aldosteronism.
Topics: Adenoma; Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aged; Aged, 80 and over; Aldos | 2010 |
Pathogenesis of hypertension: interactions among sodium, potassium, and aldosterone.
Topics: Aldosterone; Elasticity; Endothelium, Vascular; Humans; Hypertension; Male; Middle Aged; Nitric Oxid | 2010 |
Plasma renin activity and aldosterone concentration are not altered by the novel calcium channel antagonist, azelnidipine, in hypertensive patients.
Topics: Aged; Aged, 80 and over; Aldosterone; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Bloc | 2010 |
RGS2 expression and aldosterone: renin ratio modulate response to drug therapy in hypertensive patients.
Topics: Adolescent; Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Cohort Studies; Drug | 2010 |
Current Opinion in Endocrinology, Diabetes & Obesity. Editorial overview.
Topics: Adrenal Cortex; Adrenal Insufficiency; Aldosterone; Humans; Hydrocortisone; Hyperaldosteronism; Hype | 2010 |
Aldosterone/renin ratio determines peripheral and central blood pressure values over a broad range.
Topics: Aldosterone; Biomarkers; Cohort Studies; Coronary Angiography; Cross-Sectional Studies; Female; Huma | 2010 |
New insight into the role of aldosterone/renin ratio in elevated peripheral and central blood pressure.
Topics: Aldosterone; Biomarkers; Humans; Hyperaldosteronism; Hypertension; Renin; Renin-Angiotensin System | 2010 |
[A 58-year-old hypertensive patient with primary hyperaldosteronism and renal artery stenosis].
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiography; Angioplasty, Balloon; Di | 2010 |
Difficult-to-control hypertension due to bilateral aldosterone-producing adrenocortical microadenomas associated with a cortisol-producing adrenal macroadenoma.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Cushin | 2011 |
Familial adenomatous polyposis and hypertension.
Topics: Adenomatous Polyposis Coli; Adrenal Glands; Adult; Aldosterone; Humans; Hyperaldosteronism; Hyperpla | 2010 |
Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats.
Topics: Aldosterone; Animals; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Felodipine; | 2010 |
Mechanisms underlying off-target effects of the cholesteryl ester transfer protein inhibitor torcetrapib involve L-type calcium channels.
Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Aldosterone; Amides; Angiotensin II; Animals; Anticholester | 2010 |
Delayed diagnosis of primary hyperaldosteronism.
Topics: Adult; Aldosterone; Calcium Channel Blockers; Delayed Diagnosis; Dihydropyridines; Drug Resistance; | 2010 |
Long-term effects of telmisartan on blood pressure, the renin-angiotensin-aldosterone system, and lipids in hypertensive patients.
Topics: Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihyper | 2010 |
Indicators of mineralocorticoid excess in the evaluation of primary aldosteronism.
Topics: Adult; Aged; Aldosterone; Biomarkers; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertensi | 2010 |
The prevalence of metabolic syndrome and its components in two main types of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Biomarkers; Blood Pressure; Body Mass Index; C | 2010 |
Predictors of resolution of hypertension after adrenalectomy in patients with aldosterone-producing adenoma.
Topics: Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hyper | 2010 |
Licorice-induced hypertension and common variants of genes regulating renal sodium reabsorption.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adolescent; Adult; Aldosterone; Epithelial Sodium Chann | 2010 |
[The accuracy of combining aldosterone to renin ratio and low renin level in diagnosing primary aldosteronism].
Topics: Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin; ROC C | 2010 |
Metabolic syndrome and primary aldosteronism: time for reappraisal?
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Biomarkers; Blood Pressure; Body Mass Index; Humans; | 2010 |
Association of HSD3B1 and HSD3B2 gene polymorphisms with essential hypertension, aldosterone level, and left ventricular structure.
Topics: Adult; Aldosterone; Case-Control Studies; Echocardiography; Female; Genotype; Haplotypes; Humans; Hy | 2010 |
Aldosterone inhibition and cardiovascular protection: more important than it once appeared.
Topics: Aldosterone; Atherosclerosis; Blood Vessels; Cardiomegaly; Cardiotonic Agents; Endothelium; Heart Fa | 2010 |
The aldosterone-renin ratio based on the plasma renin activity and the direct renin assay for diagnosing aldosterone-producing adenoma.
Topics: Adenoma; Adult; Aged; Aldosterone; Blood Chemical Analysis; Captopril; Female; Humans; Hyperaldoster | 2010 |
Increased levels of oxidative stress, subclinical inflammation, and myocardial fibrosis markers in primary aldosteronism patients.
Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; C-Reactive Protein; Cardiomyopathies; Case-Control S | 2010 |
Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice.
Topics: Aldosterone; Animals; Blood Pressure; Cardiomegaly; Cardiovascular Diseases; Fibrosis; Heart; Hypert | 2010 |
Association of DNA polymorphisms within the CYP11B2/CYP11B1 locus and postoperative hypertension risk in the patients with aldosterone-producing adenomas.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; China; Cytochro | 2010 |
Salt-induced cardiac hypertrophy and interstitial fibrosis are due to a blood pressure-independent mechanism in Wistar rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agen | 2010 |
Severity of obstructive sleep apnea is related to aldosterone status in subjects with resistant hypertension.
Topics: Adult; Aged; Aldosterone; Comorbidity; Cross-Sectional Studies; Drug Resistance; Female; Humans; Hyp | 2010 |
HO-1 attenuates hypertension-induced inflammation/oxidative stress: support from Bartter's/Gitelman's patients.
Topics: Aldosterone; Angiotensin II; Bartter Syndrome; Blood Pressure; Heme Oxygenase-1; Humans; Hypertensio | 2010 |
Genetic analyses of the chimeric CYP11B1/CYP11B2 gene in a Korean family with glucocorticoid-remediable aldosteronism.
Topics: Adolescent; Aldosterone; Asian People; Cytochrome P-450 CYP11B2; Dexamethasone; Family; Female; Gluc | 2010 |
Endogenous ouabain and the renin-angiotensin-aldosterone system: distinct effects on Na handling and blood pressure in human hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Kidney Tubules; Linear Models; Mal | 2011 |
Cardiovascular correlates of insulin resistance in normotensive and hypertensive African Americans.
Topics: Adolescent; Adult; Aldosterone; Black or African American; Blood Glucose; Blood Pressure; Cardiac Ou | 2011 |
Clinical relevance of dietary salt intake on aldosterone and the aldosterone-to-renin ratio as screening parameters for primary aldosteronism.
Topics: Age Factors; Aldosterone; Antihypertensive Agents; Cross-Sectional Studies; Female; Humans; Hyperald | 2010 |
High plasma aldosterone concentration is a novel risk factor of cognitive impairment in patients with hypertension.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Cognition; Cognition Disorders; Female; Humans; Hyperte | 2011 |
A mother/daughter case of familial hyperaldosteronism.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Antihypertensive Agents; Biomarkers; Blo | 2010 |
A genome-wide association study of hypertension-related phenotypes in a Japanese population.
Topics: Adult; Aged; Alcohol Drinking; Aldosterone; Asian People; Biomarkers; Blood Pressure; Body Mass Inde | 2010 |
Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects?
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme | 2010 |
Misdiagnosis of two cases of primary aldosteronism owing to failure of computed tomography to detect adrenal microadenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Diagnostic Errors; Fem | 2010 |
Dietary sodium, aldosterone, and left ventricular mass changes during long-term inhibition of the renin-angiotensin system.
Topics: Adult; Aged; Aldosterone; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypert | 2010 |
A novel atrial natriuretic peptide based therapeutic in experimental angiotensin II mediated acute hypertension.
Topics: Acute Disease; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Atrial Natriuretic Fac | 2010 |
The relationship between osteopontin and adiponectin in patients with essential hypertension.
Topics: Adiponectin; Aged; Aldosterone; C-Reactive Protein; Female; Humans; Hypertension; Male; Middle Aged; | 2010 |
[Variants of surgical management for severe arterial hypertension combined with type 2 diabetes mellitus].
Topics: Adult; Aged; Aldosterone; Atherosclerosis; Cadaver; Diabetes Mellitus, Type 2; Female; Follow-Up Stu | 2010 |
Prenatal overexposure to glucocorticoids programs renal 11β-hydroxysteroid dehydrogenase type 2 expression and salt-sensitive hypertension in the rat.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Animals, Newborn; Blood Pressure; | 2011 |
Amlodipine suppressed cardiac gene expression of brain natriuretic peptide, transforming growth factor-β₁ and fibronectin mediated by aldosterone in male stroke-prone spontaneously hypertensive rats.
Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium C | 2010 |
High prevalence of liddle syndrome phenotype among hypertensive US Veterans in Northwest Louisiana.
Topics: Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Bicarbonates; Blood Pressure; Cross-S | 2010 |
Overnight rostral fluid shift and obstructive sleep apnea in treatment resistant hypertension: connecting the dots clarifies the picture.
Topics: Aldosterone; Blood Volume; Drug Resistance; Fluid Shifts; Humans; Hypertension; Insulin Resistance; | 2010 |
Current diagnosis and treatment of primary aldosteronism.
Topics: Adrenal Cortex; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocortic | 2010 |
Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Drug Interactions; Electrop | 2011 |
Aldosterone-to-renin ratio and home blood pressure in subjects with higher and lower sodium intake: the Ohasama study.
Topics: Aged; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Sectional Studies; F | 2011 |
Aldosterone/Mineralocorticoid receptor stimulation induces cellular senescence in the kidney.
Topics: Acetylglucosaminidase; Aldosterone; Animals; Blood Pressure; Blotting, Western; Cells, Cultured; Cel | 2011 |
The development of a whole-cell based medium throughput screening system for the discovery of human aldosterone synthase (CYP11B2) inhibitors: old drugs disclose new applications for the therapy of congestive heart failure, myocardial fibrosis and hyperte
Topics: Aldosterone; Cytochrome P-450 CYP11B2; Drug Discovery; Drug Evaluation, Preclinical; Fibrosis; Heart | 2011 |
Adrenal venous sampling but not computed tomography is essential before undertaking adrenalectomy for primary aldosteronism.
Topics: Adenoma; Adrenal Glands; Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hyperaldostero | 2011 |
The dangers of mandating policy in the absence of clear evidence.
Topics: Aldosterone; Evidence-Based Medicine; Humans; Hypertension; Sodium Chloride, Dietary | 2011 |
[Effects of Bai-Chuan capsule on left ventricular hypertrophy and correlative indexes].
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Apiaceae; Blood Pressure; Capsules; C | 2010 |
Aldosterone alters the participation of endothelial factors in noradrenaline vasoconstriction differently in resistance arteries from normotensive and hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Collagen Type I; Endothelium, Vascular; Gene Expression Regula | 2011 |
A rare case of ACTH-independent macronodular adrenal hyperplasia associated with aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aldost | 2011 |
Medicine. The genetics of primary aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Animals; Disease Mode | 2011 |
K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Cell Line; Cell Proli | 2011 |
Primary aldosteronism among newly diagnosed and untreated hypertensive patients in a Swedish primary care area.
Topics: Adrenal Glands; Adult; Aged; Aldosterone; Blood Specimen Collection; Female; Fludrocortisone; Humans | 2011 |
Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men.
Topics: Aldosterone; Blood Pressure; Diabetes Mellitus, Type 2; Gene Frequency; Genotype; Hemodynamics; Huma | 2011 |
Relative contributions of mitochondria and NADPH oxidase to deoxycorticosterone acetate-salt hypertension in mice.
Topics: Acetophenones; Albuminuria; Aldosterone; Animals; Blood Pressure; Cell Line; Desoxycorticosterone; D | 2011 |
Verification and evaluation of aldosteronism demographics in the Taiwan Primary Aldosteronism Investigation Group (TAIPAI Group).
Topics: Adenoma; Aldosterone; Cohort Studies; Demography; Female; Humans; Hyperaldosteronism; Hypertension; | 2011 |
Cardiovascular changes in patients with primary aldosteronism after surgical or medical treatment.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adult; Aged; Aldosterone; Blood | 2012 |
Higher aldosterone and lower N-terminal proatrial natriuretic peptide as biomarkers of salt sensitivity in the community.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Down-Regulation; Fe | 2011 |
Arterial hypertension in obesity: relationships with hormone and anthropometric parameters.
Topics: Adult; Aldosterone; Biomarkers; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory | 2011 |
Eplerenone potentiates protective effects of amlodipine against cardiovascular injury in salt-sensitive hypertensive rats.
Topics: Aldosterone; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Drug Th | 2011 |
Impact of aldosterone synthase gene C-344T polymorphism on IgA nephropathy.
Topics: Adult; Aldosterone; Biopsy; Cytochrome P-450 CYP11B2; Disease Progression; Female; Genotype; Glomeru | 2011 |
Mineralocorticoid receptor activation: a major contributor to salt-induced renal injury and hypertension in young rats.
Topics: Acute Kidney Injury; Aldosterone; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Ani | 2011 |
Frequency of familial hyperaldosteronism type 1 in a hypertensive pediatric population: clinical and biochemical presentation.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Child; Child, Preschool; Chile; Comorbidity; Cross-S | 2011 |
New take on the role of angiotensin II in cardiac hypertrophy and fibrosis.
Topics: Aldosterone; Angiotensin II; Animals; Cardiomegaly; Fibrosis; Humans; Hypertension; Inflammation; Mi | 2011 |
Is familial hyperaldosteronism underdiagnosed in hypertensive children?
Topics: Aldosterone; Blood Pressure; Child; Chile; Comorbidity; Cytochrome P-450 CYP11B2; Family Health; Gen | 2011 |
A clinical phenotype mimicking essential hypertension in a newly discovered family with Liddle's syndrome.
Topics: Adolescent; Adult; Aged; Aldosterone; Amiloride; Epithelial Sodium Channels; Female; Humans; Hyperte | 2011 |
High prevalence of autonomous aldosterone secretion among patients with essential hypertension.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aged; Aldosterone; Blood Pressure; Case-Control St | 2011 |
NKCC2 is activated in Milan hypertensive rats contributing to the maintenance of salt-sensitive hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Diuretics; Furosemide; Humans; Hypertension; Kidney; Male; Pro | 2011 |
Dysregulation of renal transient receptor potential melastatin 6/7 but not paracellin-1 in aldosterone-induced hypertension and kidney damage in a model of hereditary hypomagnesemia.
Topics: Aldosterone; Animals; Claudins; Disease Models, Animal; Hypercalciuria; Hypertension; Membrane Prote | 2011 |
Effect of the plasminogen-plasmin system on hypertensive renal and cardiac damage.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Fibrinolysin; Fibrosis | 2011 |
Diagnosis of glucocorticoid-remediable aldosteronism in hypertensive children.
Topics: Adolescent; Adult; Aldosterone; Child; Chimera; Cytochrome P-450 CYP11B2; Dexamethasone; Female; Glu | 2011 |
Transcriptome analysis of aldosterone-regulated genes in human vascular endothelial cell lines stably expressing mineralocorticoid receptor.
Topics: Aldosterone; Animals; Aorta; Cell Line; Endothelial Cells; Endothelium, Vascular; Gene Expression; G | 2011 |
[Flaccid paraplegia revealing an adenoma of Conn: a case report].
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Biomarkers; Fem | 2012 |
[Correction of aldosterone level as marker of RAAS dysfunction in patients with arterial hypertension degree II-III and chronic kidney diseases].
Topics: Aged; Aldosterone; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme In | 2011 |
Association of the aldosterone synthase gene -344T>C polymorphism with essential hypertension and glucose homeostasis: a case-control study in a Han Chinese population.
Topics: Aldosterone; Asian People; Blood Glucose; Blood Pressure; Case-Control Studies; China; Cytochrome P- | 2011 |
Impact of leptin-mediated sympatho-activation on cardiovascular function in obese mice.
Topics: Aldosterone; Animals; Blood Pressure; Cardiovascular System; Dietary Fats; Heart Rate; Hypertension; | 2011 |
Coexisting renal artery aneurysm and adrenal adenoma in resistant hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Aneurysm; Female; Humans; Hyperaldosteronism; Hyperte | 2011 |
Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice.
Topics: Aldosterone; Animals; Aquaporin 2; Aromatic-L-Amino-Acid Decarboxylases; Cyclooxygenase 2; Dopamine; | 2011 |
Aldosterone, mortality, and acute ischaemic events in coronary artery disease patients outside the setting of acute myocardial infarction or heart failure.
Topics: Age Factors; Aged; Aldosterone; Angioplasty, Balloon, Coronary; Body Mass Index; Brain Ischemia; C-R | 2012 |
Plasma catecholamines in Nigerians with primary hypertension.
Topics: Adult; Aldosterone; Black People; Blood Glucose; Case-Control Studies; Catecholamines; Epinephrine; | 2011 |
Resistant hypertension and undiagnosed primary hyperaldosteronism detected by use of a computerized database.
Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Clinical Pharmacy Information Systems; D | 2011 |
Aldosterone induces electrical remodeling independent of hypertension.
Topics: Aldosterone; Animals; Hypertension; Male; Rats; Rats, Wistar; Tachycardia, Ventricular; Ventricular | 2013 |
Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway.
Topics: Aldosterone; Animals; Hypertension; Kidney; Kidney Diseases; Male; Mice; Mice, Transgenic; Models, B | 2011 |
Effects of antihypertensive treatment on endothelial function in postmenopausal hypertensive women. A significant role for aldosterone inhibition.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Demography; Endothelium, Vascular; Female; Fol | 2011 |
A comparison between sphygmomanometer-based and ambulatory blood pressure monitoring in acute salt loading and depletion protocol.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure Monitoring, Ambulatory; Diuretics; Female; Furosemide | 2011 |
Endothelial progenitor cells in primary aldosteronism: a biomarker of severity for aldosterone vasculopathy and prognosis.
Topics: Adenoma; Adult; Aged; Aldosterone; Apoptosis; Arteries; Biomarkers; C-Reactive Protein; Cell Count; | 2011 |
Aldosterone-to-renin ratio and nocturnal blood pressure decline in a general population: the Ohasama study.
Topics: Aged; Aldosterone; Blood Pressure; Circadian Rhythm; Cross-Sectional Studies; Female; Humans; Hypert | 2011 |
Blood pressure, thyroid-stimulating hormone, and thyroid disease prevalence in primary aldosteronism and essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension; Insulin Resist | 2011 |
[Effect of qianyang recipe on correlated indices of hypertension rats of gan-yang hyperactivity syndrome].
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Calcitonin Gene-Related Peptide; Dr | 2011 |
Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension.
Topics: Aldosterone; Animals; Aorta, Thoracic; Blood Pressure; Blotting, Western; Cyclic GMP; Disease Models | 2011 |
Pattern of adrenal morphology and function in patients with acromegaly.
Topics: Acromegaly; Adrenal Glands; Adult; Aldosterone; Female; Glucose Tolerance Test; Human Growth Hormone | 2012 |
Angiotensin II acts through the angiotensin 1a receptor to upregulate pendrin.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anion Transport Prote | 2011 |
A role for cardiotrophin-1 in myocardial remodeling induced by aldosterone.
Topics: Aldosterone; Animals; Blood Pressure; Blotting, Western; Collagen; Cytokines; Disease Models, Animal | 2011 |
Role of the renin-angiotensin-aldosterone system in the enhancement of salt sensitivity caused by prenatal protein restriction in stroke-prone spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Cytochrome P-450 CYP11B2; Diet, Protein-Restricted; Female; Hypertension; Kidn | 2012 |
Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome.
Topics: Aldosterone; Angiotensin II; Animals; Animals, Genetically Modified; Blood Platelets; Humans; Hypert | 2011 |
Aldosterone-producing adenoma formation in the adrenal cortex involves expression of stem/progenitor cell markers.
Topics: Adenoma; Adrenal Cortex; Adrenal Glands; Aldosterone; Biomarkers; Cell Proliferation; Gene Expressio | 2011 |
L/N-type calcium channel blocker suppresses reflex aldosterone production induced by antihypertensive action.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Block | 2012 |
What is the role of aldosterone excess in resistant hypertension and how should it be investigated and treated?
Topics: Aldosterone; Eplerenone; Female; Humans; Hyperaldosteronism; Hyperkalemia; Hypertension; Male; Miner | 2011 |
Hyperparathyroidism in patients with primary aldosteronism: cross-sectional and interventional data from the GECOH study.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Cross-Sectional Studies; Data In | 2012 |
Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aldosterone; Animals; Antihypertensive Agents; Biomar | 2011 |
Conn's syndrome unmasked by thiazide-induced hypokalaemia.
Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Blood Pressure Monitoring, Ambulatory; Diagnosis, | 2011 |
Plasma aldosterone levels and development of insulin resistance: prospective study in a general population.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Aldosterone; Blood Glucose; Cross-Sectional Studie | 2011 |
Targeted mutation of SLC4A5 induces arterial hypertension and renal metabolic acidosis.
Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Aldosterone; Animals; Atrial Natriuretic Factor; Blo | 2012 |
Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice.
Topics: Actins; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cellular Sene | 2012 |
The epistasis between vascular homeostasis genes is apparent in essential hypertension.
Topics: Adult; Aldosterone; Analysis of Variance; Blood Pressure; Case-Control Studies; Chi-Square Distribut | 2012 |
PVN adenovirus-siRNA injections silencing either NOX2 or NOX4 attenuate aldosterone/NaCl-induced hypertension in mice.
Topics: Adenoviridae; Aldosterone; Animals; Autonomic Nervous System; Blood Pressure; Female; Genetic Therap | 2012 |
T regulatory lymphocytes prevent aldosterone-induced vascular injury.
Topics: Adaptive Immunity; Adoptive Transfer; Aldosterone; Animals; Endothelium, Vascular; Hypertension; Imm | 2012 |
[Aldosterone/renin ratio in the diagnosis of primary aldosteronism].
Topics: Adult; Aldosterone; Argentina; Blood Pressure; Cross-Sectional Studies; Female; Humans; Hyperaldoste | 2011 |
Reversibility of the effects of aliskiren in the renal versus systemic circulation.
Topics: Adult; Aged; Aldosterone; Amides; Analysis of Variance; Angiotensin II; Antihypertensive Agents; Blo | 2012 |
Lack of validation of a same-day outpatient protocol for determination of salt sensitivity of blood pressure.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Protocols; Furosemide; Humans; Hypertension; Inpatients | 2012 |
Endogenous aldosterone is involved in vascular calcification in rat.
Topics: Aldosterone; Alkaline Phosphatase; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals | 2012 |
Adrenalectomy improves increased carotid intima-media thickness and arterial stiffness in patients with aldosterone producing adenoma.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Analysis of Vari | 2012 |
The effects of ethanol upon hydric balance and arterial pressure in rats: folic acid as a possible hypotensor.
Topics: Alcohol Drinking; Alcohol-Induced Disorders; Aldosterone; Animals; Antihypertensive Agents; Creatini | 2012 |
Activation of mineralocorticoid receptors in the rostral ventrolateral medulla is involved in hypertensive mechanisms in stroke-prone spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Eplerenone; Hypertension; Male; Medulla Oblongata; Microinject | 2012 |
Myocardial migration by fibroblast progenitor cells is blood pressure dependent in a model of angII myocardial fibrosis.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cell Movement; Collagen; Fibroblasts; Fibrosis | 2012 |
Sex-specific effects of spironolactone on blood pressure in gonadectomized male and female Wistar rats.
Topics: Aldosterone; Animals; Blood Pressure; Female; Gonads; Humans; Hypertension; Male; Mineralocorticoid | 2012 |
11β-hydroxysteroid dehydrogenase type 2 polymorphisms and activity in a Chilean essential hypertensive and normotensive cohort.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Case-Control Studies; Chile; Cohort Studie | 2012 |
Primary aldosteronism: are we missing the wood for the trees?
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Pract | 2012 |
Neuroendocrine changes and natriuresis in response to social stress in rats.
Topics: Aldosterone; Analysis of Variance; Animals; Behavior, Animal; Catecholamines; Chronic Disease; Corti | 2012 |
Lessons from Africa: the importance of measuring plasma renin and aldosterone in resistant hypertension.
Topics: Africa; Aldosterone; Antihypertensive Agents; Black or African American; Drug Resistance; Female; Hu | 2012 |
Antihypertensive and cardiorenal protective effects of SM-368229, a novel mineralocorticoid receptor antagonist, in aldosterone/salt-treated rats.
Topics: Acetylglucosaminidase; Aldosterone; Animals; Antihypertensive Agents; Benzoxazines; Biomarkers; Bloo | 2012 |
Pattern of adrenal hormonal secretion in patients with adrenal adenomas: the relevance of aldosterone in arterial hypertension.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenoco | 2012 |
Unilateral primary aldosteronism with spontaneous remission after long-term spironolactone therapy.
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Antihypertensive Agents; Cardiomegaly; Enalapril; Human | 2012 |
The development of hypertension and hyperaldosteronism in a rodent model of life-long obesity.
Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Body Weight; Cytochrome P-450 CYP11B2; Dietary | 2012 |
A case of myelolipoma with bilateral adrenal hyperaldosteronism cured after unilateral adrenalectomy.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Comorbidity; Humans; Hyperaldosteronism; Hypert | 2012 |
Biphasic time course of the changes in aldosterone biosynthesis under high-salt conditions in Dahl salt-sensitive rats.
Topics: Adrenal Glands; Aldosterone; Animals; Disease Models, Animal; Hypertension; Immunohistochemistry; Ma | 2012 |
Urinary corticosteroid excretion predicts left ventricular mass and proteinuria in chronic kidney disease.
Topics: Aged; Aldosterone; Biomarkers; Cross-Sectional Studies; Desoxycorticosterone; Female; Gas Chromatogr | 2012 |
Effects of proangiotensin-12 infused continuously over 14 days in conscious rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme | 2012 |
Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice.
Topics: Aldosterone; Amiloride; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensi | 2012 |
[Peculiarities of cardiac contractile function in patients with arterial hypertension depending on temperament and anxiety state].
Topics: Adult; Aldosterone; Anxiety; Comorbidity; Diastole; Echocardiography; Humans; Hypertension; Hypertro | 2011 |
Blood pressure response to angiotensin II is enhanced in obese Zucker rats and is attributed to an aldosterone-dependent mechanism.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Hypertension; Male; Obesity; Ra | 2012 |
The concentration of blood pressure regulating hormones in premenopausal women with isolated systolic hypertension related to hyperthyroidism.
Topics: Aldosterone; Blood Pressure; Female; Humans; Hypertension; Hyperthyroidism; Renin | 2012 |
Aldosterone-to-renin ratio as a predictor of stroke under conditions of high sodium intake: the Ohasama study.
Topics: Adult; Aged; Aldosterone; Female; Humans; Hypertension; Incidence; Japan; Male; Middle Aged; Prospec | 2012 |
TASK-3 channel deletion in mice recapitulates low-renin essential hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Gene Expression Regulation; Humans; Hy | 2012 |
Screening for primary aldosteronism in hypertensive subjects: results from two German epidemiological studies.
Topics: Adult; Aged; Aldosterone; Comorbidity; Female; Germany; Health Surveys; Humans; Hyperaldosteronism; | 2012 |
Prediction of primary vs secondary hypertension in children.
Topics: Adolescent; Aldosterone; Biomarkers; Catecholamines; Child; Child, Preschool; Creatinine; Echocardio | 2012 |
A rare cause of hypertension in a healthy 2-year-old female: questions.
Topics: Adrenal Cortex Function Tests; Adrenal Hyperplasia, Congenital; Aldosterone; Antihypertensive Agents | 2012 |
Aldosterone inhibits antifibrotic factors in mouse hypertensive heart.
Topics: Aldosterone; Animals; Animals, Newborn; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blo | 2012 |
Plasma aldosterone is increased in class 2 and 3 obese essential hypertensive patients despite drug treatment.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Press | 2012 |
Low plasma renin activity and high aldosterone/renin ratio are associated with untreated isolated systolic hypertension.
Topics: Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System; | 2012 |
Dietary sodium intake and cardiovascular mortality: controversy resolved?
Topics: Aldosterone; Blood Pressure; Cardiovascular Diseases; Cholesterol; Humans; Hypertension; Male; Middl | 2012 |
Leptin and aldosterone in sympathetic activity in resistant hypertension with or without type 2 diabetes.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; | 2012 |
Polymorphic variation of CYP11B2 predicts postoperative resolution of hypertension in patients undergoing adrenalectomy for aldosterone-producing adenomas.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Cytochrome P-450 CYP11 | 2012 |
Natriuretic peptide receptor guanylyl cyclase-A protects podocytes from aldosterone-induced glomerular injury.
Topics: Acute Kidney Injury; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured; | 2012 |
Macrophage mineralocorticoid receptor signaling plays a key role in aldosterone-independent cardiac fibrosis.
Topics: Aldosterone; Angiotensin Amide; Animals; Fibrosis; Heart; Hypertension; Macrophages; Male; Mice; Mic | 2012 |
Aldosterone inhibits the fetal program and increases hypertrophy in the heart of hypertensive mice.
Topics: Aldosterone; Animals; Cardiomegaly; Cyclic AMP Response Element-Binding Protein; Female; Fetus; Gene | 2012 |
Basal and postprandial serum levels of gastrin in normotensive and hypertensive adults.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Case-Control Studies; Fasting; Female; Gastrins; | 2013 |
[Hypertension-induced fibrosis: a balance story].
Topics: Aldosterone; Angiotensin II; Animals; Bone Morphogenetic Proteins; Cardiomegaly; Disease Models, Ani | 2012 |
Long-term food restriction attenuates age-related changes in the expression of renal aldosterone-sensitive sodium transporters in Wistar-Kyoto rats: a comparison with SHR.
Topics: Aging; Aldosterone; Animals; Body Mass Index; Food Deprivation; Hydrogen Peroxide; Hypertension; Kid | 2012 |
One-hour upright posture is an ideal position for serum aldosterone concentration and plasma renin activity measuring on primary aldosteronism screening.
Topics: Adult; Aldosterone; China; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension | 2012 |
Plasma and urinary metanephrines determined by an enzyme immunoassay, but not serum chromogranin A for the diagnosis of pheochromocytoma in patients with adrenal mass.
Topics: Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Chromogranin A; Diagnosis, Diff | 2012 |
Aldosterone-producing adrenocortical carcinoma without hypertension.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adult; Aldosterone; Biopsy; Femal | 2012 |
Prospective appraisal of the prevalence of primary aldosteronism in hypertensive patients presenting with atrial flutter or fibrillation (PAPPHY Study): rationale and study design.
Topics: Aldosterone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Biomarkers; Chi-Square Dis | 2013 |
Different polymorphisms of the mineralocorticoid receptor gene are associated with either glucocorticoid or mineralocorticoid levels in hypertension.
Topics: Adult; Aldosterone; DNA; Exons; Female; Genotype; Glucocorticoids; Haplotypes; Humans; Hydrocortison | 2012 |
Interferon-γ ablation exacerbates myocardial hypertrophy in diastolic heart failure.
Topics: Aldosterone; Animals; Autophagy; Disease Models, Animal; Disease Progression; Fibrosis; Heart Failur | 2012 |
Hyperparathyroidism can be useful in the identification of primary aldosteronism due to aldosterone-producing adenoma.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Calcium; Comor | 2012 |
Sixteen years experience in six cases of Conn syndrome in Jakarta.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Alkalosis; Female; Humans; Hyperaldosteronism; | 2012 |
[Differences of blood plasma renin activity, angiotensin II and aldosterone levels in essential or secondary hypertension].
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hyperaldosteronism; Hypertensi | 2012 |
Positive association between aldosterone-renin ratio and carotid intima-media thickness in hypertensive children.
Topics: Adolescent; Aldosterone; Carotid Intima-Media Thickness; Child; Female; Humans; Hypertension; Male; | 2013 |
Influence of salt intake on target organ damages in treated hypertensive patients.
Topics: Aged; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antih | 2012 |
Increased microparticle production and impaired microvascular endothelial function in aldosterone-salt-treated rats: protective effects of polyphenols.
Topics: Aldosterone; Animals; Antioxidants; Aorta; Arterial Pressure; Cell-Derived Microparticles; Endotheli | 2012 |
Aldosterone and stress-dependent arterial hypertension.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Blood Pressure; Hypertension; Male; Rats; Stress, Phy | 2011 |
High-circulating leptin levels are associated with increased blood pressure in uncontrolled resistant hypertension.
Topics: Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pressure; Blood Pressure Monitoring, A | 2013 |
Cerebrovascular consequences of pseudohyperaldosteronism.
Topics: Adolescent; Adult; Aged; Aldosterone; Child; Child, Preschool; Cohort Studies; Epithelial Sodium Cha | 2012 |
Task3 potassium channel gene invalidation causes low renin and salt-sensitive arterial hypertension.
Topics: Adaptation, Physiological; Adrenal Glands; Aldosterone; Animals; Blood Pressure; Calcium; Cells, Cul | 2012 |
Persistent hypertension after adrenalectomy for an aldosterone-producing adenoma: weight as a critical prognostic factor for aldosterone's lasting effect on the cardiac and vascular systems.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Body Mass Index | 2012 |
Aldosterone acting through the central nervous system sensitizes angiotensin II-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Hypertension; Hypothalamus; M | 2012 |
Expression of aldosterone synthase and adrenocorticotropic hormone receptor in adrenal incidentalomas from normotensive and hypertensive patients: Distinguishing subclinical or atypical primary aldosteronism from adrenal incidental
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Asymptomatic Diseases; Biomark | 2012 |
Increasing peripheral insulin sensitivity by protein tyrosine phosphatase 1B deletion improves control of blood pressure in obesity.
Topics: Adrenergic alpha-1 Receptor Agonists; Albuminuria; Aldosterone; Animals; Blood Pressure; Dose-Respon | 2012 |
Transient prehypertensive treatment in spontaneously hypertensive rats: a comparison of losartan and amlodipine regarding long-term blood pressure, cardiac and renal protection.
Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardioton | 2012 |
Generalized glucocorticoid resistance caused by a novel two-nucleotide deletion in the hormone-binding domain of the glucocorticoid receptor gene NR3C1.
Topics: Adult; Aldosterone; Animals; Base Sequence; Coronary Artery Disease; COS Cells; Female; Frameshift M | 2013 |
Adrenal histologic findings show no difference in clinical presentation and outcome in primary hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Antihypertensive Agent | 2013 |
Blood pressure has only minor influence on aldosterone-induced oxidative stress and DNA damage in vivo.
Topics: Aldosterone; Animals; Apoptosis; Blood Pressure; Cell Transformation, Neoplastic; Cells, Cultured; C | 2013 |
Association of elevated plasma aldosterone-to-renin ratio with future cardiovascular events in patients with essential hypertension.
Topics: Adult; Aged; Aldosterone; Asian People; Cardiovascular Diseases; Cohort Studies; Essential Hypertens | 2012 |
Galectin-3 mediates aldosterone-induced vascular fibrosis.
Topics: Aldosterone; Animals; Blood Pressure; Cells, Cultured; Collagen Type I; Disease Models, Animal; Fibr | 2013 |
Screening for primary aldosteronism in a primary care unit.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Cohort Studies; Female; Humans; H | 2013 |
Hypertension caused by primary hyperaldosteronism: increased heart damage and cardiovascular risk.
Topics: Aged; Aldosterone; Blood Pressure; Cardiovascular Diseases; Cohort Studies; Female; Heart Diseases; | 2013 |
MDR-1 C3435T polymorphism may affect blood pressure in resistant hypertensive patients independently of its effects on aldosterone release.
Topics: Adult; Aged; Aldosterone; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transp | 2014 |
Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs: effects of aging and long-term aldosterone infusion.
Topics: Aging; Aldosterone; Animals; Cell Membrane Permeability; Dogs; Female; Hypertension; Hypertrophy, Le | 2013 |
Elevation of angiotensin-II type-1-receptor autoantibodies titer in primary aldosteronism as a result of aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Autoantibodies; Autoimmunity; Diagnosis | 2013 |
Differential predictors of insulin resistance in nondiabetic salt-resistant and salt-sensitive subjects.
Topics: Adult; Aldosterone; Black People; Blood Glucose; Creatinine; Diet, Sodium-Restricted; Epinephrine; F | 2013 |
Cholecalciferol administration blunts the systemic renin-angiotensin system in essential hypertensives with hypovitaminosis D.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Cholecalciferol; Essential Hypertension; Female; Humans; H | 2014 |
Increased dietary sodium is related to severity of obstructive sleep apnea in patients with resistant hypertension and hyperaldosteronism.
Topics: Aldosterone; Blood Pressure; Comorbidity; Cross-Sectional Studies; Female; Humans; Hyperaldosteronis | 2013 |
Cardiovascular effects of Tulbaghia violacea Harv. (Alliaceae) root methanolic extract in Dahl salt-sensitive (DSS) rats.
Topics: Aldosterone; Allium; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Male; Medicine, | 2013 |
The contributions of muscarinic receptors and changes in plasma aldosterone levels to the anti-hypertensive effect of Tulbaghia violacea.
Topics: Aldosterone; Allium; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Captopril; Heart Ra | 2013 |
Suppression of primary aldosteronism and resistant hypertension by the peroxisome proliferator-activated receptor gamma agonist pioglitazone.
Topics: Aldosterone; Blood Pressure; Comorbidity; Humans; Hyperaldosteronism; Hypertension; Male; Middle Age | 2013 |
Structural insights into aldosterone synthase substrate specificity and targeted inhibition.
Topics: Aldosterone; Blood Pressure; Catalysis; Crystallography, X-Ray; Cytochrome P-450 CYP11B2; Desoxycort | 2013 |
Role of hypothalamic angiotensin type 1 receptors in pressure overload-induced mineralocorticoid receptor activation and salt-induced sympathoexcitation.
Topics: Aldosterone; Animals; Aorta, Thoracic; Blood Pressure; Blotting, Western; Epithelial Sodium Channels | 2013 |
Association of aldosterone with left ventricular mass in hypertension: interaction with plasma fibrinogen levels.
Topics: Adult; Aged; Aldosterone; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Heart Ventricl | 2013 |
Abnormal aldosterone physiology and cardiometabolic risk factors.
Topics: Aldosterone; Cross-Sectional Studies; Female; Humans; Hypertension; Incidence; Male; Metabolic Syndr | 2013 |
Dopaminergic modulation of aldosterone secretions on changes of sodium intake in aldosterone-producing adenoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Blood Pressure; Diet, Sodium-R | 2002 |
Structural changes in small resistance arteries and left ventricular geometry in patients with primary and secondary hypertension.
Topics: Adult; Aged; Aldosterone; Arteries; Echocardiography; Female; Heart Ventricles; Humans; Hypertension | 2002 |
Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor.
Topics: Adrenomedullin; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anim | 2002 |
TIMP-1: a marker of left ventricular diastolic dysfunction and fibrosis in hypertension.
Topics: Aldosterone; Blood Pressure; Cohort Studies; Collagen; Collagen Type I; Echocardiography; Electrocar | 2002 |
PAI-1 in human hypertension: relation to hypertensive groups.
Topics: Adult; Aldosterone; Data Interpretation, Statistical; Female; Fibrinogen; Humans; Hypertension; Insu | 2002 |
Soluble cell adhesion molecules in hypertensive concentric left ventricular hypertrophy.
Topics: Adult; Aged; Aldosterone; Carotid Arteries; Case-Control Studies; Cell Adhesion Molecules; E-Selecti | 2002 |
Contribution of endothelin-1 to renal activator protein-1 activation and macrophage infiltration in aldosterone-induced hypertension.
Topics: Aldosterone; Analysis of Variance; Animals; Dansyl Compounds; DNA; Electrophoretic Mobility Shift As | 2002 |
Variation at the aldosterone synthase (CYP11B2) locus contributes to hypertension in subjects with a raised aldosterone-to-renin ratio.
Topics: Aldosterone; Base Sequence; Blood Pressure; Creatinine; Cytochrome P-450 CYP11B2; DNA Primers; Femal | 2002 |
Is cardiovascular remodeling in patients with essential hypertension related to more than high blood pressure? A LIFE substudy. Losartan Intervention For Endpoint-Reduction in Hypertension.
Topics: Aged; Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood Vess | 2002 |
High plasma adrenomedullin concentrations in patients with high-renin essential hypertension.
Topics: Adrenomedullin; Adult; Aldosterone; Humans; Hypertension; Middle Aged; Peptides; Renin | 2002 |
Influence of antihypertensive medication on aldosterone and renin concentration in the differential diagnosis of essential hypertension and primary aldosteronism.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Diagnosi | 2002 |
Variant of pre-clinical Cushing's syndrome: hypertension and hypokalemia associated with normoreninemic normoaldosteronism.
Topics: Adenoma; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Cushing Syndrome; Cyt | 2002 |
[Effect of isosorbide mononitrate on hypotensive action of enalapril in patients with mild and moderate hypertension].
Topics: Administration, Oral; Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypert | 2002 |
High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Humans; Hyperaldost | 2002 |
Aldosterone induces a vascular inflammatory phenotype in the rat heart.
Topics: Aldosterone; Animals; Blood Pressure; Chemokine CCL2; Coronary Vessels; Cyclooxygenase 2; Endomyocar | 2002 |
Primary hyperaldosteronism as a cause of hypertension.
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin | 1967 |
Screening for primary aldosteronism: implications of an increased plasma aldosterone/renin ratio.
Topics: Adult; Aldosterone; Black People; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Age | 2002 |
New insights into the role of aldosterone in cardiorenal disease and the clinical implications. Introduction.
Topics: Aldosterone; Heart Failure; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Randomized | 2002 |
[Selective aldosterone blocker for hypertension and heart failure. Better tolerance than previous drugs].
Topics: Aldosterone; Clinical Trials as Topic; Eplerenone; Heart Failure; Humans; Hypertension; Spironolacto | 2002 |
Long-term follow-up and cost benefit of adrenalectomy in patients with primary hyperaldosteronism.
Topics: Adrenalectomy; Aldosterone; Antihypertensive Agents; Blood Pressure; Cost-Benefit Analysis; Female; | 2002 |
Selective aldosterone blockade prevents angiotensin II/salt-induced vascular inflammation in the rat heart.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Body Weight; Coronary Disease; Coronary Vessels | 2002 |
Brain natriuretic peptide as a risk marker for incident hypertensive cardiovascular events.
Topics: Aged; Aging; Aldosterone; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Catecholamines; Dis | 2002 |
Investigation of the role of aldosterone in hypertension associated with spontaneous pituitary-dependent hyperadrenocorticism in dogs.
Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldosterone; Animals; Antineoplastic Agen | 2002 |
PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Cell Adhesion Molecules; C | 2002 |
Endothelin receptor blockade lowers plasma aldosterone levels via different mechanisms in primary aldosteronism and high-to-normal renin hypertension.
Topics: Adrenocorticotropic Hormone; Aldosterone; Endothelin Receptor Antagonists; Female; Humans; Hydrocort | 2003 |
Asymmetry of renal blood flow in patients with moderate to severe hypertension.
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Radiography; R | 2003 |
The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related.
Topics: Adult; Aldosterone; Animals; Binding, Competitive; Corticosterone; Cortisone; COS Cells; Female; Hum | 2003 |
Increased salt sensitivity induced by impairment of sensory nerves: is nephropathy the cause?
Topics: Aldosterone; Animals; Animals, Newborn; Blood Pressure; Capsaicin; Denervation; Diuresis; Drinking; | 2003 |
Myocardial ultrasonic backscatter in hypertension: relation to aldosterone and endothelin.
Topics: Adult; Aldosterone; Analysis of Variance; Blood Pressure; Echocardiography; Endothelins; Female; Hum | 2003 |
[11 beta-hydroxysteroid dehydrogenase type 2 activity in Chilean patients with hypertension].
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Case-Control Studies; Chile; Chromatograph | 2002 |
20-HETE and furosemide-induced natriuresis in salt-sensitive essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Female; Furosemide; Humans; Hydroxyeicosatetraenoic Acids; Hyper | 2003 |
Renin-angiotensin-aldosterone system and G-protein beta-3 subunit gene polymorphisms in salt-sensitive essential hypertension.
Topics: Adult; Aldosterone; Blood Volume; Female; Genotype; Heterotrimeric GTP-Binding Proteins; Humans; Hyp | 2003 |
Adenovirus-mediated human prostasin gene delivery is linked to increased aldosterone production and hypertension in rats.
Topics: Adenoviridae; Aldosterone; Animals; Blood Pressure; Disease Models, Animal; Female; Gene Expression; | 2003 |
[Hormonal interactions of parathormone and calcium metabolism].
Topics: Adolescent; Adult; Aged; Aldosterone; Blood Glucose; Bone Density; Bone Resorption; Calcium; Drug Ad | 2003 |
[Vasopressin and renin-aldosterone system in patients with arterial hypertension].
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 2002 |
Dietary salt regulates renal SGK1 abundance: relevance to salt sensitivity in the Dahl rat.
Topics: Administration, Oral; Aldosterone; Animals; Blood Pressure; Gene Expression Regulation; Hypertension | 2003 |
[Conn syndrome as cause of stubborn hypertension. Which hypertensives should you screen?].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenergic beta-Antagonists; Aldosterone; Angiotens | 2003 |
Effect of Salvia miltiorrhiza on left ventricular hypertrophy and cardiac aldosterone in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Drugs, Chinese Herbal; Hypertension; Hypertrophy, Left Ventricular; Male; Myoc | 2002 |
Hypertension, angiotensin II, aldosterone, and race.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Antihypertensive Agents; Black People; Eplerenone; Hu | 2003 |
Pathologic quiz case: a 57-year-old man with hypertension and hypokalemia.
Topics: Adenocarcinoma, Clear Cell; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldoste | 2003 |
Mineralocorticoid regulation of epithelial Na+ channels is maintained in a mouse model of Liddle's syndrome.
Topics: Aldosterone; Amiloride; Animals; Disease Models, Animal; Diuretics; Epithelial Cells; Epithelial Sod | 2003 |
Effects of long-acting calcium channel antagonists on neurohumoral factors: comparison of nifedipine coat-core with amlodipine.
Topics: Aged; Aged, 80 and over; Aldosterone; Amlodipine; Blood Pressure; Calcium Channel Blockers; Chemistr | 2003 |
The epithelial Na+ channel: progressing from Liddle's syndrome to essential hypertension.
Topics: Aldosterone; Black People; Disease Progression; Genetic Predisposition to Disease; Humans; Hypertens | 2003 |
A new mutation, R563Q, of the beta subunit of the epithelial sodium channel associated with low-renin, low-aldosterone hypertension.
Topics: Adult; Aged; Aldosterone; Amino Acid Sequence; Biomarkers; Black People; Female; Genetic Predisposit | 2003 |
Association of high-altitude systemic hypertension with the deletion allele-of the angiotensin-converting enzyme (ACE) gene.
Topics: Adaptation, Physiological; Adult; Aldosterone; Altitude; Case-Control Studies; Gene Deletion; Geneti | 2003 |
Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Bu | 2003 |
Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin.
Topics: Aldosterone; Amiloride; Animals; Cell Line; Electric Conductivity; Epithelial Cells; Gene Expression | 2003 |
Aldosterone antagonism and hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Physiological Phenomena; Cardi | 2003 |
Combined effects of low-dose oral spironolactone and captopril therapy in a rat model of spontaneous hypertension and heart failure.
Topics: Administration, Oral; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriur | 2003 |
Upregulation of ligand, receptor system, and amidating activity of adrenomedullin in left ventricular hypertrophy of severely hypertensive rats: effects of angiotensin-converting enzyme inhibitors and diuretic.
Topics: Adrenomedullin; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic F | 2003 |
A biallelic gene polymorphism of CYP11B2 predicts increased aldosterone to renin ratio in selected hypertensive patients.
Topics: Adult; Aldosterone; Alleles; Cytochrome P-450 CYP11B2; Female; Gene Frequency; Genotype; Haplotypes; | 2003 |
Primary aldosteronism and hypertensive disease.
Topics: Aldosterone; Cross-Sectional Studies; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hypertens | 2003 |
Aldosterone plays a pivotal role in the pathogenesis of thrombotic microangiopathy in SHRSP.
Topics: Aldosterone; Animals; Antineoplastic Agents, Hormonal; Blood Pressure; Body Weight; Creatinine; Dexa | 2003 |
[Cytokines and remodeling of the heart in patients with congestive heart failure].
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Biomarkers; Cardiomyopathy, Dilated; Catecholam | 2003 |
[Humoral markers of endothelial dysfunction in essential hypertension].
Topics: Adult; Aldosterone; Biomarkers; Endothelium, Vascular; Humans; Hypertension; Insulin-Like Growth Fac | 2003 |
[Reninoma: a rare but curable cause of high blood pressure, a case report].
Topics: Adult; Aldosterone; Enzyme Precursors; Humans; Hypertension; Hypokalemia; Kidney Neoplasms; Renal Ve | 2003 |
Analysis of angiotensin II mediated COX-2 downregulation in angiotensin II- or aldosterone-infused hypertensive rat.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cyclooxygenase 2; Down-Regulation; Hypertensio | 2003 |
Effects of static magnetic fields on plasma levels of angiotensin II and aldosterone associated with arterial blood pressure in genetically hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Radiation; Electro | 2003 |
Brain sodium channels and ouabainlike compounds mediate central aldosterone-induced hypertension.
Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Brain Chemistry; Cardenolides; Digoxin; Heart Rate; | 2003 |
[Organization, contributions and possibilities of a department of clinical research in a French-Canadian center; aldosterone and arterial hypertension].
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Biomedical Research; Canada; Humans; Hypertens | 1955 |
Malignant hypertension and hyperaldosteronism.
Topics: Adrenal Cortex; Adrenal Cortex Diseases; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hype | 1956 |
Malignant hypertension and hyperaldosteronism.
Topics: Adrenal Cortex; Adrenal Cortex Diseases; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hype | 1956 |
Malignant hypertension and hyperaldosteronism.
Topics: Adrenal Cortex; Adrenal Cortex Diseases; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hype | 1956 |
Malignant hypertension and hyperaldosteronism.
Topics: Adrenal Cortex; Adrenal Cortex Diseases; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hype | 1956 |
Studies on aldosterone. II. Hypertension as a cumulative effect of aldosterone administration.
Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Pharmaceutical Prep | 1957 |
Studies on aldosterone. II. Hypertension as a cumulative effect of aldosterone administration.
Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Pharmaceutical Prep | 1957 |
Studies on aldosterone. II. Hypertension as a cumulative effect of aldosterone administration.
Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Pharmaceutical Prep | 1957 |
Studies on aldosterone. II. Hypertension as a cumulative effect of aldosterone administration.
Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Pharmaceutical Prep | 1957 |
Aldosterone and hypertension.
Topics: Aldosterone; Humans; Hypertension | 1957 |
Hyperaldosteronism and malignant hypertension.
Topics: Aldosterone; Humans; Hypertension | 1957 |
Production of experimental hypertension by aldosterone.
Topics: Aldosterone; Desoxycorticosterone; Humans; Hypertension | 1957 |
[Urinary excretion of aldosterone-like substances in hypertensive vascular disease].
Topics: Adrenal Cortex Hormones; Aldosterone; Body Fluids; Electrolytes; Humans; Hypertension | 1957 |
Malignant hypertension, adrenal hyperplasia and depletion of potassium.
Topics: Adrenal Cortex; Adrenal Cortex Diseases; Aldosterone; Humans; Hyperplasia; Hypertension; Hypertensio | 1957 |
Further studies on urinary aldosterone in human arterial hypertension.
Topics: Aldosterone; Body Fluids; Humans; Hypertension | 1958 |
Antihypertensive effects of an aldosterone antagonist.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Mineralocorticoid Recept | 1958 |
ALDOSTERONE antagonists as antihypertensive agents.
Topics: Aldosterone; Antihypertensive Agents; Humans; Hypertension; Mineralocorticoid Receptor Antagonists | 1958 |
Studies on new diuretic compounds: spirolactone and chlorothiazide.
Topics: Acetazolamide; Aldosterone; Chlorothiazide; Diuretics; Hypertension; Mineralocorticoid Receptor Anta | 1958 |
Prevention by adrenal-regeneration hypertension by an aldosterone-blocker.
Topics: Adrenal Gland Diseases; Adrenalectomy; Aldosterone; Humans; Hypertension; Mineralocorticoid Receptor | 1959 |
[Hyperaldosteronism with adenomatous hyperplasia of the adrenals in a case of hypertension with refractory edema].
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Aldosterone; Edema; Humans; Hyperaldostero | 1959 |
Aldosteronism and hypertension: the influence of complete adrenalectomy upon essential hypertension in a child.
Topics: Adrenalectomy; Aldosterone; Child; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension; | 1959 |
Primary hyperaldosteronism and related hypertension. Surgical management.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension | 1961 |
Body fluid and electrolyte composition in arterial hypertension. II. Studies in mineralocorticoid hypertension.
Topics: Aldosterone; Body Fluids; Electrolytes; Humans; Hypertension; Mineralocorticoids | 1961 |
Primary aldosteronism versus hypertensive disease with secondary aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 1961 |
Aldosteronism and hypertension. Primary aldosteronism versus hypertensive disease with secondary aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 1961 |
Aldosterone excretion in essential hypertension.
Topics: Aldosterone; Biological Transport; Body Fluids; Essential Hypertension; Humans; Hypertension | 1960 |
Studies of the pathogenesis of human hypertension. The adrenal cortex and renal pressor mechanism.
Topics: Adrenal Cortex; Aldosterone; Angiotensin Amide; Hypertension; Kidney; Vasoconstrictor Agents | 1961 |
Study of a large steroid spectrum in normal subjects and hypertensive patients.
Topics: Adrenal Cortex Hormones; Aldosterone; Body Fluids; Hypertension; Pregnanediol; Steroids | 1960 |
Angiotensin, aldosterone and human arterial hypertension.
Topics: Aldosterone; Angiotensin Amide; Angiotensins; Body Fluids; Hypertension | 1961 |
Spironolactone in hypertensive patients. Oligemic and antihypertensive effects.
Topics: Aldosterone; Antihypertensive Agents; Blood Volume; Diuretics; Humans; Hypertension; Mineralocortico | 1961 |
[Hypertension and aldosterone].
Topics: Aldosterone; Hypertension | 1960 |
Secondary hyperaldosteronism associated with hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 1961 |
Primary aldosteronism with severe hypertension relieved by adrenalectomy.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hy | 1961 |
[Urinary excretion of aldosterone in essential hypertension. Investigations by a chemical method].
Topics: Aldosterone; Body Fluids; Essential Hypertension; Humans; Hypertension | 1960 |
[Daily rhythm of the secretion of aldosterone in patients with hypertension].
Topics: Aldosterone; Humans; Hypertension; Periodicity | 1961 |
[On the intervention of the angiotensin-aldosterone system in the pathogenesis of arterial hypertension].
Topics: Aldosterone; Angiotensin Amide; Angiotensins; Hypertension | 1961 |
Aldosteronism and arterial hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 1961 |
Relation of aldosterone secretion to hypertensive vascular disease.
Topics: Aldosterone; Biological Transport; Cell Communication; Humans; Hypertension | 1961 |
[The urinary excretion of aldosterone in hypertensive patients].
Topics: Aldosterone; Body Fluids; Humans; Hypertension | 1961 |
Primary aldosteronism--a new and curable hypertensive syndrome.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Syndrome | 1961 |
Urinary aldosterone and hypertension.
Topics: Aldosterone; Humans; Hypertension | 1961 |
[Conn's syndrome and essential arterial hypertension].
Topics: Aldosterone; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension | 1960 |
Essential hypertension and aldosterone.
Topics: Aldosterone; Essential Hypertension; Humans; Hypertension | 1961 |
Remediable hypertension.
Topics: Aldosterone; Humans; Hypertension; Kidney; Kidney Diseases; Pheochromocytoma | 1959 |
[Natruresis and aldosterone excretion in essential hypertension].
Topics: Aldosterone; Biological Transport; Body Fluids; Essential Hypertension; Humans; Hypertension; Sodium | 1959 |
[Venous hypertension and hyperproduction of aldosterone: experimental research].
Topics: Adrenal Glands; Aldosterone; Cardiovascular System; Humans; Hypertension | 1959 |
Primary aldosteronism: a case with severe hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 1960 |
Electrolyte and corticosteroid studies in a 15-year-old girl with primary aldosteronism and malignant hypertension.
Topics: Adolescent; Adrenal Cortex Hormones; Aldosterone; Electrolytes; Female; Humans; Hyperaldosteronism; | 1960 |
[Quantitative determination of aldosterone in urine of patients with hypertension].
Topics: Aldosterone; Humans; Hypertension | 1959 |
[Secondary hyperaldosteronism in the course of arterial hypertension].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Vascular Diseases | 1960 |
An evaluation of the electrocardiogram and the acidity of the urine as a screening test for primary aldosteronism.
Topics: Aldosterone; Electrocardiography; Humans; Hyperaldosteronism; Hypertension | 1959 |
[Aldosterone production of the adrenal gland in experimental renal hypertension].
Topics: Adrenal Glands; Aldosterone; Humans; Hypertension; Hypertension, Renal | 1960 |
Effects of angiotensin infusions on aldosterone and electrolyte excretion in normal subjects and patients with hypertension and adrenocortical disorders.
Topics: Adrenal Cortex; Adrenal Cortex Diseases; Aldosterone; Angiotensins; Body Fluids; Electrolytes; Human | 1962 |
[On the effects of aldosterone antagonists on high blood pressure].
Topics: Aldosterone; Humans; Hypertension; Mineralocorticoid Receptor Antagonists | 1962 |
Aldosterone secretion in hypertensive diseases.
Topics: Aldosterone; Humans; Hypertension; Lipid Metabolism | 1962 |
The effects of spironolactone and chlorthalidone on arterial pressure.
Topics: Aldosterone; Arterial Pressure; Blood Pressure; Chlorthalidone; Diuretics; Humans; Hypertension; Min | 1962 |
Primary hyperaldosteronism, a curable form of hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 1962 |
Primary aldosteronism. Case observed in a patient subjected previously to thoracolumbar sympathectomy.
Topics: Aldosterone; Chlorothiazide; Humans; Hyperaldosteronism; Hypertension; Sympathectomy | 1962 |
Effect of thiazide diuretics on plasma volume, body electrolytes, and excretion of aldosterone in hypertension.
Topics: Aldosterone; Biological Transport; Blood Volume; Chlorothiazide; Electrolytes; Hypertension; Plasma | 1961 |
New approaches in the study of cardiovascular disease: aldosterone, renin, hypertension and juxtaglomerular cells.
Topics: Adrenal Cortex; Aldosterone; Cardiovascular Diseases; Humans; Hypertension; Juxtaglomerular Apparatu | 1961 |
Surgical treatment of hypertension -- primary aldosteronism. A review of 13 cases.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Essential Hypertension; Humans; Hyperaldoster | 1962 |
Effect of chlorothiazide upon aldosterone excretion and sodium and potassium balance in essential hypertension.
Topics: Aldosterone; Body Fluids; Chlorothiazide; Essential Hypertension; Humans; Hypertension; Potassium; S | 1962 |
Influence of alterations in sodium intake on urinary aldosterone response to corticotropin in normal individuals and patients with essential hypertension.
Topics: Adrenocorticotropic Hormone; Aldosterone; Diet; Essential Hypertension; Humans; Hypertension; Nutrit | 1962 |
An explanation of hypertension produced by narrowing the renal artery.
Topics: Aldosterone; Humans; Hypertension; Hypertension, Renal; Natriuresis; Renal Artery; Renin | 1963 |
The effect of aldosterone on electrolytes and on digital vascular reactivity to 1-norepinephrine in normotensive, hypertensive, and hypotensive subjects.
Topics: Aldosterone; Blood Flow Velocity; Blood Pressure; Blood Pressure Determination; Electrolytes; Humans | 1963 |
Further evidence for a role of the renin-angiotensin system in regulation of aldosterone secretion.
Topics: Aldosterone; Humans; Hypertension; Renin; Renin-Angiotensin System | 1963 |
[Mechanism of the development of renal hypertension].
Topics: Aldosterone; Epinephrine; Humans; Hypertension; Hypertension, Renal; Kidney; Norepinephrine; Renin | 1962 |
Humoral factors in essential hypertension.
Topics: Aldosterone; Essential Hypertension; Humans; Hypertension; Renin | 1963 |
[Urinary aldosterone in subjects with hypertension].
Topics: Aldosterone; Humans; Hypertension | 1963 |
[Aspects of the hormonal regulation of aldosterone biosynthesis].
Topics: Adrenocorticotropic Hormone; Aldosterone; Humans; Hypertension; Lipogenesis; Pineal Gland; Tissue Ex | 1963 |
[Sodium metabolism and hypertension].
Topics: Aldosterone; Humans; Hypertension; Hypertension, Renal; Kidney; Sodium | 1963 |
Juxtaglomerular cells, aldosterone, renin and hypertension.
Topics: Aldosterone; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney; Renin | 1962 |
Renal hypertension with elevated aldosterone. Case due to muscular hypertrophy cured by nephrectomy with decline of aldosterone levels to normal.
Topics: Aldosterone; Humans; Hypertension; Hypertension, Renal; Hypertrophy; Kidney; Nephrectomy | 1963 |
Hypertension and increased aldosterone excretion associated with unilateral renal artery stenosis.
Topics: Aldosterone; Humans; Hyperparathyroidism; Hypertension; Hypertension, Pulmonary; Renal Artery Obstru | 1963 |
[Internal secretion and hypertension. Aldosterone and hypertension].
Topics: Aldosterone; Humans; Hypertension | 1962 |
[Influence of angiotensin activity on renal electrolyte and water excretion caused by pretreatment with aldosterone].
Topics: Aldosterone; Angiotensins; Electrolytes; Hypertension; Kidney; Potassium; Sodium; Sodium, Dietary; W | 1963 |
Influence of aldosterone and angiotensin II on endotoxin shock in the primate.
Topics: Aldosterone; Angiotensin II; Animals; Endotoxins; Humans; Hypertension; Primates; Shock; Shock, Sept | 1963 |
The rate of aldosterone secretion in hypertensive patients with demonstrable renal artery stenosis.
Topics: Aldosterone; Humans; Hypertension; Hypertension, Malignant; Renal Artery Obstruction | 1963 |
[Intervention of aldosterone and electrolytes in the pathogenesis of essential hypertension].
Topics: Aldosterone; Electrolytes; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension; Sodium; | 1962 |
[Determination of loosely bound aldosterone in the blood of healthy and sick people].
Topics: Aldosterone; Humans; Hypertension; Hypertension, Renal; Kidney; Liver Cirrhosis; Nephrotic Syndrome | 1963 |
Isolation of a polar aldosterone-like substance from the urine and adrenal incubates of patients with arterial hypertension.
Topics: Aldosterone; Humans; Hypertension | 1963 |
[Influence of aldosterone on the intradermal test with angiotensin].
Topics: Aldosterone; Angiotensins; Humans; Hypertension; Intradermal Tests; Skin Tests | 1963 |
[Studies on the urinary excretion of aldosterone. II. On the role of aldosterone in the pathogenesis of some clinical syndromes].
Topics: Aldosterone; Diabetes Insipidus; Edema; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Liv | 1962 |
[Treatment of shock, considered irreversible, with angiotensin and aldosterone].
Topics: Aldosterone; Angiotensins; Humans; Hypertension; Shock | 1963 |
Angiotensin pressor inhibition by aldosterone in the rabbit.
Topics: Aldosterone; Angiotensin II; Angiotensins; Animals; Blood Pressure; Hypertension; Rabbits; Renin | 1963 |
ALDOSTERONE SECRETION AND VARIOUS FORMS OF HYPERTENSIVE VASCULAR DISEASE.
Topics: Adrenal Gland Neoplasms; Aldosterone; Angiotensins; Humans; Hypertension; Ischemia; Renal Artery; Re | 1963 |
[HYPOKALEMIA, ALDOSTERONE EXCRETION AND PRIMARY HYPERALDOSTERONISM].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Hypokalemia; Kidney; Uri | 1963 |
MALIGNANT HYPERTENSION AND ALDOSTERONE SECRETION. INFLUENCE OF REVERSAL AND PROGRESSION OF THE SYNDROME IN TWO CASES.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Spironolactone; Urem | 1963 |
EXPERIMENTAL STUDIES ON THE RELATIONSHIP BETWEEN ENDOCRINE ORGANS AND HYPERTENSION IN SPONTANEOUSLY HYPERTENSIVE RATS. II. EFFECTS OF VARIOUS HORMONES ON BLOOD PRESSURE.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Arginine Vasopressin; Blood Pressure; Body Weight | 1963 |
ETIOLOGIC MECHANISMS IN PREHYPERTENSION.
Topics: Aldosterone; Genetics, Medical; Hypertension; Metabolism; Nervous System; Physiology; Prehypertensio | 1963 |
ALDOSTERONE AND CORTICOSTERONE SECRETION RATES IN RATS WITH EXPERIMENTAL RENAL HYPERTENSION.
Topics: Aldosterone; Chromatography; Corticosterone; Hypertension; Hypertension, Renal; Kidney; Nephrectomy; | 1963 |
[ALDOSTERONURIA IN DIFFERENT HYPERTENSIVE STATES].
Topics: Aldosterone; Body Fluids; Humans; Hypertension; Urine | 1963 |
ALDOSTERONE AND THE EDEMA OF CONGESTIVE HEART FAILURE.
Topics: Aldosterone; Chromatography; Diuretics; Edema; Geriatrics; Heart Diseases; Heart Failure; Hypertensi | 1964 |
[RENAL HYPERTENSION].
Topics: Aldosterone; Angiotensins; Blood Vessel Prosthesis; Humans; Hypertension; Hypertension, Renal; Kidne | 1963 |
[HORMONAL FACTORS IN CARDIAC INSUFFICIENCY].
Topics: Aldosterone; Angiotensins; Catecholamines; Heart Failure; Humans; Hypertension; Hyperthyroidism; Met | 1963 |
EFFECTS OF ALDOSTERONE AND OTHER ADRENAL HORMONES ON THE BLOOD PRESSURE RESPONSES TO RENIN AND ANGIOTENSIN.
Topics: Aldosterone; Angiotensins; Animals; Blood Pressure; Corticosterone; Desoxycorticosterone; Female; Hy | 1964 |
VARIATIONS IN PLASMA RENIN CONCENTRATION IN SEVERAL PHYSIOLOGICAL AND PATHOLOGICAL STATES.
Topics: Addison Disease; Aldosterone; Angiotensins; Blood Chemical Analysis; Hypertension; Hypokalemia; Live | 1964 |
THE RENIN CONTENT OF THE BLOOD OF HUMANS AND DOGS UNDER SEVERAL CONDITIONS.
Topics: Aldosterone; Blood Chemical Analysis; Diet, Sodium-Restricted; Dogs; Edema; Hyperaldosteronism; Hype | 1964 |
MEASUREMENT OF HUMAN ARTERIAL RENIN ACTIVITY IN SOME PHYSIOLOGICAL AND PATHOLOGICAL STATES.
Topics: Aldosterone; Angiotensins; Arteries; Arteriosclerosis; Blood Chemical Analysis; Blood Pressure; Diet | 1964 |
RELATIONS BETWEEN RENIN, ALDOSTERONE AND EXPERIMENTAL HYPERTENSION IN RATS.
Topics: Aldosterone; Blood Pressure; Hypertension; Hypertension, Renal; Kidney; Rats; Renal Artery; Renin; R | 1964 |
INTERACTION BETWEEN ALDOSTERONE SECRETION, SODIUM AND POTASSIUM BALANCE, AND ANGIOTENSIN ACTIVITY IN MAN: STUDIES IN HYPERTENSION AND CIRRHOSIS.
Topics: Adrenal Glands; Aldosterone; Angiotensins; Blood Pressure; Edema; Humans; Hyperaldosteronism; Hypert | 1964 |
THE ROLE OF THE RENIN-ANGIOTENSIN SYSTEM IN BLOOD PRESSURE REGULATION AND KIDNEY FUNCTION.
Topics: Adrenal Glands; Aldosterone; Angiotensins; Blood Chemical Analysis; Blood Circulation; Blood Pressur | 1964 |
THE ROLE OF THE RENIN-ANGIOTENSIN SYSTEM IN THE HYPERTENSION ASSOCIATED WITH RENAL VASCULAR DISEASE.
Topics: Aldosterone; Angiotensins; Blood Chemical Analysis; Hypertension; Hypertension, Renal; Kidney; Kidne | 1964 |
HYPERTENSION DUE TO RENAL ARTERY OCCLUSION SIMULATING PRIMARY ALDOSTERONISM.
Topics: Aldosterone; Angiotensins; Blood Chemical Analysis; Blood Pressure; Hyperaldosteronism; Hypertension | 1964 |
EXPERIMENTAL STUDIES ON THE RELATIONSHIP BETWEEN ENDOCRINE ORGANS AND HYPERTENSION IN SPONTANEOUSLY HYPERTENSIVE RATS. III. ROLE OF THE ENDOCRINE ORGANS AND HORMONES.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Animals; Arginine Vasopressin; Cortisone; D | 1964 |
[ALDOSTERONE SECRETION RATE IN VARIOUS DISEASES].
Topics: Aldosterone; Cushing Syndrome; Diabetic Nephropathies; Heart Diseases; Humans; Hyperaldosteronism; H | 1963 |
[DIAGNOSIS AND TREATMENT OF ADDISON'S DISEASE].
Topics: Addison Disease; Adrenal Cortex Hormones; Adrenal Insufficiency; Adrenocorticotropic Hormone; Aldost | 1963 |
[NATRIURETIC DRUGS].
Topics: Acetazolamide; Aldosterone; Ascites; Chlorothiazide; Dexamethasone; Diabetes Insipidus; Diuresis; Di | 1963 |
ALDOSTERONE SECRETION RATE AND ELECTROLYTE BALANCE STUDIES ON THREE PATIENTS WITH HYPERTENSION. INFLUENCE OF GUANETHIDINE, HYDRALAZINE AND METHYCLOTHIAZIDE.
Topics: Aldosterone; Diet, Sodium-Restricted; Diuretics; Guanethidine; Heart Diseases; Humans; Hydralazine; | 1964 |
DEMONSTRATION BY PRESSOR AND STEROIDOGENIC ASSAYS OF INCREASED RENIN IN LYMPH OF DOGS WITH SECONDARY HYPERALDOSTERONISM.
Topics: Adrenal Glands; Aldosterone; Angiotensins; Corticosterone; Dogs; Hyperaldosteronism; Hypertension; H | 1964 |
THE DIAGNOSTIC IMPLICATION OF RESTRICTION OF SALT INTAKE AND ADMINISTRATION OF VARIOUS DRUGS IN PRIMARY ALDOSTERONISM.
Topics: Aldosterone; Biomedical Research; Cushing Syndrome; Desoxycorticosterone; Diagnosis, Differential; D | 1964 |
THE JUXTAGLOMERULAR APPARATUS AND ALDOSTERONE IN HYPERALDOSTERONISM.
Topics: Aldosterone; Angiotensins; Biomedical Research; Carcinoma, Hepatocellular; Cushing Syndrome; Hepatit | 1964 |
STUDIES ON THE MECHANISMS OF HUMAN ARTERIAL HYPERTENSION.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenal Medulla; Aldosterone; Brain; Hypertension; Hyperten | 1964 |
[ADRENAL CORTEX AND HYPERTENSION].
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenalectomy; Aldosterone; Angiotensins; Chlorothiazide; D | 1964 |
[ALDOSTERONE AND SPIROLACTONES IN THE CLINICAL TREATMENT OF INTERNAL DISEASES (REVIEW OF THE LITERATURE AND ANALYSIS OF PERSONAL CASES)].
Topics: Albuminuria; Aldosterone; Blood; Cardiovascular Diseases; Drug Therapy; Humans; Hyperaldosteronism; | 1963 |
[PATHOPHYSIOLOGY AND CLINICAL ASPECTS OF SECONDARY ALDOSTERONISM AND ITS TREATMENT].
Topics: Adrenocorticotropic Hormone; Aldosterone; Ascites; Body Fluids; Classification; Dexamethasone; Extra | 1964 |
BLOOD VOLUME, TOTAL BODY WATER AND ALDOSTERONE EXCRETION IN ESSENTIAL HYPERTENSION.
Topics: Aldosterone; Blood Volume; Blood Volume Determination; Body Fluids; Body Water; Chromium Isotopes; E | 1964 |
EXPERIMENTAL HYPERTENSIONS TREATED WITH CCL-4: MEASUREMENTS OF ADRENAL FUNCTION, VASCULAR RESPONSIVENESS, ANGIOTENSINASE AND CONVERTING ENZYME.
Topics: Aldosterone; Angiotensins; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; C | 1964 |
STEROID BIOSYNTHESIS BY RAT ADRENAL: DURING DEVELOPMENT OF ADRENAL REGENERATION AND DESOXYCORTICOSTERONE ACETATE-INDUCED HYPERTENSION.
Topics: Acetates; Adrenal Glands; Adrenalectomy; Aldosterone; Chromatography; Corticosterone; Desoxycorticos | 1964 |
ANGIOTENSIN, ELECTROLYTES AND ALDOSTERONE.
Topics: Adrenal Glands; Aldosterone; Angiotensins; Animals; Cerebral Cortex; Chlorides; Corticosterone; Dogs | 1964 |
EXPERIMENTAL ASCITES. VI. THE EFFECTS OF HEPATIC VENOUS OUTFLOW OBSTRUCTION AND ASCITES ON ALDOSTERONE SECRETION.
Topics: Adrenal Glands; Aldosterone; Ascites; Blood; Blood Pressure; Budd-Chiari Syndrome; Dogs; Hepatic Vei | 1964 |
[ON CHANGES IN BLOOD VESSEL WALL ELECTROLYTES AND THE ADRENAL CORTEX IN EXPERIMENTAL HYPERTENSION].
Topics: Adrenal Cortex; Aldosterone; Aorta; Blood Pressure Determination; Carbon Tetrachloride Poisoning; Co | 1964 |
PRIMARY ALDOSTERONISM: OBSERVATIONS IN SIX CASES AND REVIEW OF DIAGNOSTIC PROCEDURES.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Diabetes Mellitus; Diagnosis, Differen | 1964 |
[SIGNIFICANCE OF ALDOSTERONE IN THE PATHOGENESIS OF THE EDEMATOUS AND HYPERTENSIVE SYNDROME IN KIDNEY DISEASES].
Topics: Aldosterone; Blood; Edema; Glomerulonephritis; Humans; Hyperaldosteronism; Hypertension; Hypertensio | 1964 |
CHANGES IN PLASMA RENIN DURING SODIUM DEPLETION IN MAN.
Topics: Aldosterone; Angiotensins; Blood Chemical Analysis; Diet, Sodium-Restricted; Hypertension; Hypertens | 1964 |
ANGIOTENSIN.
Topics: Aldosterone; Angiotensins; Blood Pressure; Blood Pressure Determination; Hypertension; Liver; Metabo | 1964 |
BLOOD-PRESSURE HYPERREACTIVITY TO ANGIOTENSIN IN MAN.
Topics: Aldosterone; Angiotensins; Blood Pressure; Blood Pressure Determination; Blood Volume; Edema; Fluids | 1964 |
REIN-ANGIOTENSIN AND ALDOSTERONE IN EXPERIMENTAL HYPERTENSION.
Topics: Adrenal Glands; Aldosterone; Angiotensins; Animals; Aorta; Blood; Carbon Tetrachloride; Desoxycortic | 1964 |
[ON THE IMPORTANCE OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN THE PATHOGENESIS OF RENAL HYPERTENSION].
Topics: Aldosterone; Angiotensins; Diuresis; Hypertension; Hypertension, Renal; Kidney; Metabolism; Natriure | 1964 |
[ON A USEFUL MODIFICATION OF THE METHOD OF URINARY ALDOSTERONE DETERMINATION BY THIN LAYER CHROMATOGRAPHY].
Topics: Aldosterone; Chromatography; Chromatography, Thin Layer; Female; Humans; Hypertension; Premenstrual | 1964 |
[POLYCARDIOGRAPHIC INVENTORY, MICROCIRCULATORY ASPECTS AND HUMORAL EFFECTS IN JUVENILE ARTERIAL HYPERTENSION].
Topics: Adolescent; Aldosterone; Angiotensins; Blood; Capillaries; Cardiovascular System; Catecholamines; Ch | 1964 |
[HYPERALDOSTERONURIA IN THE COURSE OF JUVENILE ARTERIAL HYPERTENSION].
Topics: Adolescent; Aldosterone; Body Fluids; Chromatography; Humans; Hypertension; Urine | 1964 |
EFFECT OF ALDOSTERONE ON JUXTAGLOMERULAR INDEX AND ZONA GLOMERULOSA OF NORMOTENSIVE AND HYPERTENSIVE RATS.
Topics: Adrenal Glands; Aldosterone; Blood Pressure; Blood Pressure Determination; Hypertension; Hypertensio | 1965 |
[INVESTIGATION OF PLASMA ALDOSTERONE AND ALDOSTERONE METABOLISM IN HEALTHY SUBJECTS AND PATIENTS WITH HEART, LIVER AND KIDNEY DISEASE].
Topics: Aldosterone; Blood; Healthy Volunteers; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Hyp | 1965 |
[ALDOSTERONE AND ARTERIAL HYPERTENSION].
Topics: Aldosterone; Hypertension; Physiology; Rats; Research | 1964 |
HYPERTENSION AND HYPERSALIMENTATION. I. ALDOSTERONE HYPERTENSION.
Topics: Adrenal Glands; Aldosterone; Arteritis; Diet; Heart Diseases; Hypertension; Kidney; Metabolism; Myoc | 1965 |
[ARTERIAL HYPERTENSION, RENIN, ANGIOTENSIN, AND ALDOSTERONE].
Topics: Aldosterone; Angiotensins; Humans; Hypertension; Renin | 1965 |
NORMAL AND ALTERED FUNCTION OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN MAN: APPLICATIONS IN CLINICAL AND RESEARCH MEDICINE.
Topics: Adrenal Glands; Aldosterone; Angiotensins; Edema; Hyperaldosteronism; Hypertension; Kidney; Physiolo | 1965 |
PROLONGED INFUSIONS OF ANGIOTENSIN II AND NOREPINEPHRINE AND BLOOD PRESSURE, ELECTROLYTE BALANCE, AND ALDOSTERONE AND CORTISOL SECRETION IN NORMAL MAN AND IN CIRRHOSIS WITH ASCITES.
Topics: Aldosterone; Angiotensin II; Angiotensins; Ascites; Blood Pressure; Body Fluids; Dexamethasone; Huma | 1965 |
[Comparative studies on the hypertensive effects of aldosterone and desoxycorticosterone].
Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; Desoxycorticosterone; Humans; Hypertensio | 1955 |
Hypertension caused by renal artery occlusion simulating primary aldosteronism.
Topics: Aldosterone; Disease; Humans; Hyperaldosteronism; Hypertension; Renal Artery | 1960 |
Hypotensive agents and pressor substances. The effect of epinephrine, norepinephrine, angiotensin II, and others on the secretory rate of aldosterone in man.
Topics: Aldosterone; Angiotensin Amide; Angiotensin II; Antihypertensive Agents; Catecholamines; Epinephrine | 1960 |
Aldosterone secretion and primary and malignant hypertension.
Topics: Aldosterone; Biological Transport; Humans; Hypertension; Hypertension, Malignant; Lipid Metabolism | 1960 |
Electrolyte metabolism and aldosterone secretion in benign and malignant hypertension.
Topics: Aldosterone; Electrolytes; Humans; Hypertension; Hypertension, Malignant | 1960 |
The role of aldosterone in man. Evidence for regulation of electrolyte balance and arterial pressure by a renal-adrenal system which may be involved in malignant hypertension.
Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Hypertension, Malig | 1960 |
Effects of an acute salt load in a case of primary hyperaldo-steronism before and nine months after surgical cure: comparison with normal subjects and patients with essential hypertension before and after reduction of their elevated pressure with drug tre
Topics: Aldosterone; Essential Hypertension; Humans; Hypertension; Sodium Chloride; Sodium Chloride, Dietary | 1959 |
Hypertension and hypokalaemia associated with hypo-aldosteronism.
Topics: Aldosterone; Child; Humans; Hyperaldosteronism; Hypertension; Hypoaldosteronism; Hypokalemia; Infant | 1959 |
[False Conn syndromes].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Medical Records; Potassium; Tetany | 1960 |
Hypertension associated with hypokalemia and alkalosis simulating primary hyperaldosteronism: report of a case.
Topics: Aldosterone; Alkalosis; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Potassium; Vascular D | 1959 |
On the influence of body water volume and potassium supply on the aldosterone excretion in arterial hypertension.
Topics: Aldosterone; Biological Transport; Body Composition; Body Water; Diuretics; Humans; Hypertension; Po | 1962 |
[Influence of spirolactones on manifestations of experimental renal hypertension].
Topics: Aldosterone; Diuretics; Hypertension; Hypertension, Renal; Kidney; Leadership; Mineralocorticoid Rec | 1962 |
Hypertension and renal loss of potassium.
Topics: Aldosterone; Humans; Hypertension; Kidney; Potassium; Potassium Deficiency | 1961 |
Hormones and the pathogenesis of congestive heart failure: vasopressin, aldosterone, and angiotensin II. Further evidence for renal-adrenal interaction from studies in hypertension and in cirrhosis.
Topics: Aldosterone; Angiotensin Amide; Angiotensin II; Heart Defects, Congenital; Heart Failure; Humans; Hy | 1962 |
Experimental vascular disease elicited by aldosterone and renin.
Topics: Aldosterone; Angiotensin Amide; Blood Vessels; Disease; Humans; Hypertension; Renin; Vascular Diseas | 1962 |
Aldosteronism and hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 1962 |
Urinary aldosterone and hypertension.
Topics: Aldosterone; Body Fluids; Humans; Hypertension; Ions; Sodium; Sodium, Dietary | 1962 |
[Hypertension and aldosterone].
Topics: Aldosterone; Anions; Humans; Hypertension; Ions; Potassium; Sodium; Sodium, Dietary | 1962 |
[Contribution to the treatment of essential hypertension.(Control of blood pressure, active blood volume, venous pressure, circulation time and mineral metabolism after Repicin and spirolactone medication)].
Topics: Aldosterone; Blood Circulation Time; Blood Pressure; Blood Pressure Determination; Blood Volume; Chl | 1962 |
The role of biochemical tests and clinical symptoms in differential diagnosis of primary aldosteronism.
Topics: Adult; Age Factors; Aged; Aldosterone; Biomarkers; Blood Pressure; Blood Pressure Determination; Dia | 2003 |
Prevalence and role of a raised aldosterone to renin ratio in the diagnosis of primary aldosteronism: a debate on the scientific logic of the use of the ratio in practice.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Diagnosis, Differential; Diagnostic Tests, Routine; Hum | 2003 |
Primary aldosteronism, diagnosed by the aldosterone to renin ratio, is a common cause of hypertension.
Topics: Aldosterone; Antihypertensive Agents; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hyperte | 2003 |
Genetic determinants of nonmodulating hypertension.
Topics: Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Epistasis, Genetic; Family Health; Female | 2003 |
Relationship between plasma aldosterone and left ventricular structure and function in patients with essential hypertension.
Topics: Aldosterone; Echocardiography; Female; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Re | 2003 |
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosterone; Female; F | 2003 |
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosterone; Female; F | 2003 |
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosterone; Female; F | 2003 |
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosterone; Female; F | 2003 |
Human adipocytes secrete mineralocorticoid-releasing factors.
Topics: Adipocytes; Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Base Sequence; Colforsin; Culture Me | 2003 |
[Primary aldosteronism. A risk factor for aortic dissection?].
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Aortic Aneurysm; Aortic Dissec | 2003 |
Hypersensitivity of the adrenal cortex to trophic and secretory effects of angiotensin II in Lyon genetically-hypertensive rats.
Topics: Adrenal Cortex; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone | 2004 |
Effect of salt and water intake on epithelial sodium channel mRNA abundance in the kidney of salt-sensitive Sabra rats.
Topics: Aldosterone; Animals; Disease Models, Animal; Drinking; Epithelial Cells; Hypertension; Kidney Corte | 2003 |
[Influence of exercise on plasma concentration of neuropeptide Y in patients with essential hypertension].
Topics: Aldosterone; Catecholamines; Exercise; Female; Humans; Hypertension; Male; Middle Aged; Neuropeptide | 2003 |
Coexistence of different phenotypes in a family with glucocorticoid-remediable aldosteronism.
Topics: Adult; Aged; Aldosterone; Cortodoxone; Cytochrome P-450 CYP11B2; Dexamethasone; Female; Genotype; Gl | 2004 |
NAD(P)H oxidase inhibitor prevents blood pressure elevation and cardiovascular hypertrophy in aldosterone-infused rats.
Topics: Acetophenones; Aldosterone; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Collagen; Fibro | 2004 |
Serum potassium level and dietary potassium intake as risk factors for stroke.
Topics: Aged; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Potassium, Dietary; Renin; R | 2003 |
Aldosterone excretion among subjects with resistant hypertension and symptoms of sleep apnea.
Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin; Sleep Apnea | 2004 |
Diurnal blood pressure variation in pheochromocytoma, primary aldosteronism and Cushing's syndrome.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Blood Pressure; Blood Pressure Determination; Cas | 2004 |
Resistant hypertension, obesity, sleep apnea, and aldosterone: theory and therapy.
Topics: Aldosterone; Antihypertensive Agents; Drug Resistance; Humans; Hypertension; Male; Middle Aged; Mode | 2004 |
Ethnic, geographic and dietary influences upon vasoactive hormones and blood pressure among Greenland Inuit and Danes.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Denmark; Epidemi | 2003 |
Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats.
Topics: Aldosterone; Animals; Cyclic N-Oxides; Eplerenone; Hypertension; JNK Mitogen-Activated Protein Kinas | 2004 |
From inflammation to fibrosis: a stiff stretch of highway.
Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Apoptosis; Cell Adhesion Molecules; Collagen | 2004 |
Pathophysiological aspects of experimental myocardial infarction during arterial hypertension.
Topics: Adult; Aldosterone; Animals; Blood Pressure; Case-Control Studies; Disease Models, Animal; Humans; H | 2003 |
Impaired 11-beta hydroxysteroid dehydrogenase type 2 activity in sweat gland ducts in human essential hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenal Cortex Hormones; Adult; Aldosterone; Bicarbonat | 2004 |
Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents.
Topics: Aldosterone; Chile; Follow-Up Studies; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Italy; | 2004 |
Relations of serum aldosterone to cardiac structure: gender-related differences in the Framingham Heart Study.
Topics: Aged; Aldosterone; Antihypertensive Agents; Body Mass Index; Cohort Studies; Cross-Sectional Studies | 2004 |
The many targets of aldosterone.
Topics: Aldosterone; Amiloride; Body Water; Cell Size; Endothelial Cells; Endothelium, Vascular; Guanidines; | 2004 |
Diagnosis of primary aldosteronism: value of different screening parameters and influence of antihypertensive medication.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertensi | 2004 |
Relationship between hypertensive left ventricular hypertrophy, neurohormonal factors and ventricular arrhythmias in very old patients.
Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Arrhythmias, Cardiac; Biomarkers; Coronary Ang | 2004 |
Aldosterone antagonist facilitates the cardioprotective effects of angiotensin receptor blockers in hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; B | 2004 |
Increased renovascular response to angiotensin II in persons genetically predisposed to arterial hypertension disappears after chronic angiotensin-converting enzyme inhibition.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biomarkers | 2004 |
Eplerenone prevents salt-induced vascular remodeling and cardiac fibrosis in stroke-prone spontaneously hypertensive rats.
Topics: Acetylcholine; Aldosterone; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Collagen | 2004 |
Primary aldosteronism--careful investigation is essential and rewarding.
Topics: Adrenal Gland Diseases; Aldosterone; Diagnosis, Differential; Female; Hospital Units; Humans; Hypera | 2004 |
Vascular synthesis of aldosterone: role in hypertension.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Cardi | 2004 |
Impaired endothelium-dependent flow-mediated vasodilation in hypertensive subjects with hyperaldosteronism.
Topics: Adult; Aldosterone; Brachial Artery; Endothelium, Vascular; Female; Hemorheology; Humans; Hyperaldos | 2004 |
Age dependence of the levels of plasma norepinephrine, aldosterone, renin activity and urinary vanillylmandelic acid in normal and essential hypertensives.
Topics: Adolescent; Adult; Age Factors; Aldosterone; Child; Child, Preschool; Epinephrine; Female; Humans; H | 2004 |
Aldosterone regulation for 18 years in a case of primary aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Biomarkers; Calcium Channel Blockers; Humans; Hypera | 2004 |
Aldosterone modulates neural vasomotor response in hypertension: role of calcitonin gene-related peptide.
Topics: Adenine; Adenosine Triphosphate; Aldosterone; Animals; Anti-Arrhythmia Agents; Calcitonin Gene-Relat | 2004 |
Six missense mutations of the epithelial sodium channel beta and gamma subunits in Japanese hypertensives.
Topics: Aged; Aldosterone; Asian People; Epithelial Sodium Channels; Exons; Female; Genetic Predisposition t | 2004 |
Aldosterone--villain or bystander?
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin-Angiotensin System; Risk Fac | 2004 |
Serum aldosterone and the incidence of hypertension in nonhypertensive persons.
Topics: Aldosterone; Blood Pressure; Female; Heart Ventricles; Humans; Hyperaldosteronism; Hypertension; Hyp | 2004 |
[Promoter variants of aldosterone synthase gene (CYP11B2) and salt-sensitivity of blood pressure].
Topics: Adult; Aldosterone; Alleles; Blood Pressure; Cytochrome P-450 CYP11B2; Diet, Sodium-Restricted; DNA; | 2004 |
Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention.
Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Diuretics; Endothelin-1; Furosemide; Heterozygote; | 2004 |
Aldosterone-renin ratios in the context of primary care.
Topics: Aldosterone; Humans; Hypertension; Prevalence; Primary Health Care; Renin | 2004 |
Aldosterone to Renin ratio in a primary care setting: the Bussolengo study.
Topics: Adult; Age Factors; Aged; Aldosterone; Female; Humans; Hypertension; Italy; Male; Middle Aged; Renin | 2004 |
The current epidemic of primary aldosteronism: causes and consequences.
Topics: Aldosterone; Disease Outbreaks; Humans; Hyperaldosteronism; Hypertension | 2004 |
The current epidemic of primary aldosteronism: causes and consequences.
Topics: Aldosterone; Disease Outbreaks; Humans; Hyperaldosteronism; Hypertension; Renin | 2004 |
The current epidemic of primary aldosteronism: causes and consequences.
Topics: Aldosterone; Disease Outbreaks; Humans; Hyperaldosteronism; Hypertension; Renin | 2004 |
[Effect of modified liberation doxazosin on blood pressure, insulin resistance, and catecholamine secretion in patients with true resistant hypertension].
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Catecholamines; Doxazosin; Drug Resistance; Fe | 2004 |
Chronic central infusion of aldosterone leads to sympathetic hyperreactivity and hypertension in Dahl S but not Dahl R rats.
Topics: Aldosterone; Animals; Baroreflex; Blood Pressure; Cardiotonic Agents; Heart Rate; Hypertension; Inje | 2005 |
Postnatal modulation of prenatally programmed hypertension by dietary Na and ACE inhibition.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Enalapril; Female; Hype | 2005 |
A1166C polymorphism of angiotensin II type 1 receptor, blood pressure and arterial stiffness in hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Blood Flow Velocity; Blood Pressure; Female; Genotype | 2004 |
Cardioprotective effects of vasopeptidase inhibition vs. angiotensin type 1-receptor blockade in spontaneously hypertensive rats on a high salt diet.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Apoptosis; A | 2004 |
[Renin aldosterone profile in essential hypertension during pregnancy and after delivery].
Topics: Adult; Aldosterone; Blood Pressure; Case-Control Studies; Female; Humans; Hypertension; Postpartum P | 2004 |
[One hypertensive in ten affected? Renaissance of primary hyperaldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cross-Sectional Studies; Diagnosis, Differential; Hum | 2004 |
Aldosterone revisited.
Topics: Aldosterone; Humans; Hypertension; Potassium | 2004 |
Aldosterone revisited.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists | 2004 |
Aldosterone revisited.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Sodium; Sodium, Dietary | 2004 |
[Free urinary cortisol is elevated in patients with low-renin essential hypertension].
Topics: Aldosterone; Creatinine; Epidemiologic Methods; Female; Glucocorticoids; Humans; Hydrocortisone; Hyp | 2004 |
Alteration of renal adrenomedullin and its receptor system in the severely hypertensive rat: effect of diuretic.
Topics: Adrenomedullin; Aldosterone; Animals; Collagen Type I; Disease Models, Animal; Diuretics; Gene Expre | 2005 |
Plasma sodium: ignored and underestimated.
Topics: Adult; Aldosterone; Blood Pressure; Cohort Studies; Cross-Over Studies; Dose-Response Relationship, | 2005 |
The influence of aldosterone on the development of left ventricular geometry and hypertrophy in patients with essential hypertension.
Topics: Aged; Aldosterone; Body Mass Index; Echocardiography; Female; Heart Ventricles; Humans; Hypertension | 2004 |
Scientists probe aldosterone's role in hypertension and heart disease.
Topics: Aldosterone; Cardiovascular Agents; Cardiovascular Physiological Phenomena; Heart Diseases; Humans; | 2004 |
11beta-Hydroxysteroid dehydrogenase type 2 activity is associated with left ventricular mass in essential hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Blood Pressure; Cohort Studies; Cortodoxon | 2005 |
CYP11B2 gene polymorphisms and hypertension in highlanders accustomed to high salt intake.
Topics: Adult; Aged; Aldosterone; Body Mass Index; Cytochrome P-450 CYP11B2; Environment; Feeding Behavior; | 2005 |
Long-term follow-up after adrenalectomy for primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Algorithms; Antihypertensive Ag | 2005 |
Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension.
Topics: Adult; Aged; Aldosterone; Alleles; Epithelial Sodium Channels; Female; Genetic Predisposition to Dis | 2005 |
Multiple gene approaches to delineate the role of the renin-angiotensin-aldosterone system in nephropathy.
Topics: Aldosterone; Alleles; Angiotensins; Case-Control Studies; Cytochrome P-450 CYP11B2; Gene Frequency; | 2005 |
Genetic polymorphisms of the renin-angiotensin-aldosterone system and renal insufficiency in essential hypertension.
Topics: Acute Kidney Injury; Aged; Aldosterone; Case-Control Studies; Female; Humans; Hypertension; Italy; M | 2005 |
Adrenocorticotropic hormone is produced in the ventricle of patients with essential hypertension.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Aorta; Cardiac Catheterization; Case-Control | 2005 |
Prorenin cryoactivation as a possible cause of normal renin levels in patients with primary aldosteronism.
Topics: Adenoma; Aldosterone; Chymosin; Enzyme Precursors; Humans; Hyperaldosteronism; Hypertension; Immunor | 2005 |
ACE inhibitors and mineralocorticoid receptor blockade in patients with congestive heart failure.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Heart Failure; Humans; Hypertension; Mineralo | 2005 |
Fat cells may be the obesity-hypertension link: human adipogenic factors stimulate aldosterone secretion from adrenocortical cells.
Topics: Adipocytes; Adrenal Cortex; Adult; Aldosterone; Animals; Cattle; Cells, Cultured; Female; Humans; Hy | 2004 |
Hyperaldosteronism and hypertension: ethnic differences.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Black People; Blood Pressure; Blood Pressure Monitori | 2005 |
Estrogen depletion differentially affects blood pressure depending on age in Long-Evans rats.
Topics: Aldosterone; Animals; Blood Pressure; Drinking; Estradiol; Estrogen Replacement Therapy; Female; Hyp | 2004 |
The changes of serum-ACE, plasma renin activity and aldosterone in the diabetics with hypertension.
Topics: Adult; Aged; Aldosterone; Diabetes Mellitus; Female; Humans; Hypertension; Male; Middle Aged; Peptid | 1986 |
The syndromes of low-renin hypertension: "separating the wheat from the chaff".
Topics: Adenoma; Adolescent; Adult; Aged; Aldosterone; Child; Diagnosis, Differential; Female; Humans; Hyper | 2004 |
Decreased plasma levels of nitric oxide metabolites, angiotensin II, and aldosterone in spontaneously hypertensive rats exposed to 5 mT static magnetic field.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Radiation; Electro | 2005 |
Adrenocortical carcinoma producing 11-deoxycorticosterone: a rare cause of mineralocorticoid hypertension.
Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Catecholamines | 2005 |
The effects of genetic factors on selected indicators of the activity of the sympathoadrenal system and the renin-angiotensin-aldosterone system in twins.
Topics: Adrenal Glands; Adult; Aldosterone; Blood Pressure; Dopamine; Epinephrine; Female; Humans; Hypertens | 2004 |
Participation of aldosterone in the vascular inflammatory response of spontaneously hypertensive rats: role of the NFkappaB/IkappaB system.
Topics: Aldosterone; Animals; Antihypertensive Agents; Drug Therapy, Combination; Eplerenone; Hypertension; | 2005 |
Failure of angiotensin II to suppress plasma renin activity in normotensive subjects with a positive family history of hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Dos | 2005 |
Adrenocortical carcinoma with concomitant myelolipoma in a patient with hyperaldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adult; Aldosterone; Biomarkers, T | 2005 |
Alterations in aldosterone and angiotensin II levels in salt-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Glutathione; Glutathione Disulfid | 2005 |
Validity of plasma aldosterone-to-renin activity ratio in African American and white subjects with resistant hypertension.
Topics: Alabama; Aldosterone; Biomarkers; Black or African American; Blood Pressure; Female; Humans; Hyperal | 2005 |
Morbid obesity, hypertensive disease and the renin-angiotensin-aldosterone axis.
Topics: Adolescent; Adult; Aldosterone; Analysis of Variance; Anastomosis, Roux-en-Y; Female; Gastric Bypass | 2005 |
Differential effects of angiotensin II type-1 receptor antisense oligonucleotides on renal function in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Diure | 2005 |
Participation of prostacyclin in endothelial dysfunction induced by aldosterone in normotensive and hypertensive rats.
Topics: Acetylcholine; Aldosterone; Animals; Aorta, Thoracic; Blood Pressure; Drug Administration Schedule; | 2005 |
Aldosterone promotes endothelial dysfunction via prostacyclin independent of hypertension.
Topics: Aldosterone; Animals; Endothelium, Vascular; Epoprostenol; Humans; Hypertension | 2005 |
Relationship between impaired aldosterone response to adrenocorticotropic hormone and prevalence of hemodialysis in type 2 diabetic patients without azotemia.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Diabetes Mellitus, Type 2; Female; Follow-Up Studie | 2005 |
Quiz page. Secondary hypertension with contralateral pheochromocytoma and aldosteronoma.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Antihypertensive Agent | 2005 |
Prolonged attenuation of cold-induced hypertension by adenoviral delivery of renin antisense.
Topics: Adenoviridae; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cold Temperature; DNA, Antisense | 2005 |
Aldosterone in heart failure: pathophysiology and treatment.
Topics: Aldosterone; Death, Sudden, Cardiac; Endothelium, Vascular; Heart Failure; Humans; Hypertension; Min | 2004 |
Plasma aldosterone to renin ratio predicts treatment response in primary aldosteronism: is volume loading needed?
Topics: Aldosterone; Diagnosis, Differential; Diagnostic Techniques, Endocrine; Female; Fludrocortisone; Hum | 2005 |
c-Src-dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Hypertension; Mal | 2005 |
[Role of hormones in volume regulating kidney function in patients with hypertension].
Topics: Aldosterone; Atrial Natriuretic Factor; Diuresis; Hormones; Humans; Hypertension; Kidney; Kidney Fun | 2005 |
Low-renin hypertension with relative aldosterone excess is associated with impaired NO-mediated vasodilation.
Topics: Adult; Aged; Aldosterone; Case-Control Studies; Female; Forearm; Humans; Hyperaldosteronism; Hyperte | 2005 |
Urinary prostasin: a candidate marker of epithelial sodium channel activation in humans.
Topics: Adult; Aged; Aldosterone; Biomarkers; Blotting, Western; Case-Control Studies; Diuretics; Dose-Respo | 2005 |
Paradoxic activation of the renin-angiotensin system in twin-twin transfusion syndrome: an explanation for cardiovascular disturbances in the recipient.
Topics: Adult; Aldosterone; Cardiomyopathies; Cardiovascular System; Down-Regulation; Fatal Outcome; Female; | 2005 |
Angiotensin-converting enzyme 2 (ACE2) and ACE activities display tissue-specific sensitivity to undernutrition-programmed hypertension in the adult rat.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Blood Press | 2005 |
Simvastatin and losartan enhance nitric oxide and reduce oxidative stress in salt-induced hypertension.
Topics: Acetylcholine; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; | 2005 |
Prevalence of primary hyperaldosteronism in mild to moderate hypertension without hypokalaemia.
Topics: Aldosterone; Black People; Cross-Over Studies; Female; Humans; Hyperaldosteronism; Hypertension; Hyp | 2006 |
Increased number of aldosterone-sensitive NTS neurons in Dahl salt-sensitive rats.
Topics: Aldosterone; Animals; Cell Count; Hydroxysteroid Dehydrogenases; Hypertension; Immunohistochemistry; | 2005 |
Does aldosterone-to-renin ratio predict the antihypertensive effect of the aldosterone antagonist spironolactone?
Topics: Aldosterone; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Female; Humans; Hypertens | 2005 |
Role of aldosterone in angiotensin II-induced cardiac and aortic inflammation, fibrosis, and hypertrophy.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Collagen; Ectodysplasins; Fibrosis; Heart; Hypertension | 2005 |
Neurogenic mechanisms contribute to hypertension in mice with disruption of the K-Cl cotransporter KCC3.
Topics: Aldosterone; Animals; Calcium; Chlorides; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Mu | 2006 |
Aldosterone-induced abnormal regulation of ENaC and SGK1 in Dahl salt-sensitive rat.
Topics: Aldosterone; Animals; Blotting, Western; Body Weight; Epithelial Sodium Channels; Extracellular Sign | 2006 |
[Microsatellite marker AGAT of the mineralocorticoid receptor gene is associated with plasma renin activity in patients with essential hypertension].
Topics: Aldosterone; Alleles; Body Mass Index; Case-Control Studies; Female; Genetic Markers; Genotype; Huma | 2005 |
Increased renal alpha-ENaC and NCC abundance and elevated blood pressure are independent of hyperaldosteronism in vasopressin escape.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenalectomy; Aldosterone; Animals; Blood Pressure; Co | 2006 |
Cardiac consequences of aldosterone excess in human hypertension.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; | 2006 |
Role of aldosterone in left ventricular hypertrophy in hypertension.
Topics: Adrenergic beta-Antagonists; Adrenocortical Adenoma; Adult; Aldosterone; Angiotensin II; Blood Press | 2006 |
Aldosterone and left ventricular hypertrophy in Afro-Caribbean subjects with low renin hypertension.
Topics: Adult; Aged; Aldosterone; Black People; Blood Pressure; Caribbean Region; Echocardiography; Female; | 2006 |
Too much aldosterone--more common than we ever realized?
Topics: Adult; Aged; Aldosterone; Black People; Blood Pressure; Caribbean Region; Female; Humans; Hypertensi | 2006 |
Long-term results of adrenalectomy in patients with aldosterone-producing adenomas: multivariate analysis of factors affecting unresolved hypertension and review of the literature.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Female; H | 2005 |
Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and failure in low-aldosterone hypertensive rats.
Topics: Aldosterone; Animals; Cardiac Output, Low; Cardiomegaly; Cardiotonic Agents; Coronary Vessels; Corti | 2006 |
Mineralocorticoid receptors and cardiovascular damage: it's not just aldosterone.
Topics: Aldosterone; Animals; Cardiac Output, Low; Cardiomegaly; Cardiotonic Agents; Corticosterone; Epleren | 2006 |
[Diagnosis and treatment outcome in primary aldosteronism based on a retrospective analysis of 187 cases].
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Cytochrome P-450 CYP11B2 | 2006 |
Obesity-induced hypertension develops in young rats independently of the renin-angiotensin-aldosterone system.
Topics: Acetylcholine; Aging; Aldosterone; Animals; Blood Glucose; Cardiovascular System; Dietary Fats; Dise | 2006 |
Altered vascular contractility in adult female rats with hypertension programmed by prenatal glucocorticoid exposure.
Topics: Acetylcholine; Aldosterone; Angiotensin II; Animals; Animals, Newborn; Aorta; Corticosterone; Dexame | 2006 |
[Primary hyperaldosteronism: should we pose its systematic detection at health centres?].
Topics: Aldosterone; Blood Chemical Analysis; Clinical Trials as Topic; Humans; Hyperaldosteronism; Hyperten | 2006 |
Effects of enalapril, tempol, and eplerenone on salt-induced hypertension in dahl salt-sensitive rats.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Blood | 2006 |
Effect of prepuberal gonadectomy upon aldosterone levels in female and male SHR: interaction between blood pressure and kallikrein kinin system.
Topics: Aging; Aldosterone; Animals; Biomarkers; Blood Pressure; Castration; Disease Models, Animal; Disease | 2006 |
Blood pressure reduction in pregnancy by sodium chloride.
Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Hypoaldosteronism; Pregnancy; Preg | 2006 |
Cardioprotective mechanisms of spironolactone associated with the angiotensin-converting enzyme/epidermal growth factor receptor/extracellular signal-regulated kinases, NAD(P)H oxidase/lectin-like oxidized low-density lipoprotein receptor-1, and Rho-kinas
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Chemokine CCL2; Coronary Vessels; Er | 2005 |
John Arthur Luetscher, Jr (1903-2005).
Topics: Aldosterone; Cardiology; History, 20th Century; Humans; Hypertension; United States | 2006 |
Aldosterone and refractory hypertension: a prospective cohort study.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Cohort Studies; Drug Resistance; Female; Follo | 2006 |
The prevalence of primary aldosteronism in diabetic patients.
Topics: Aldosterone; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Hyperaldosteronism; H | 2006 |
Activation of brain renin-angiotensin-aldosterone system by central sodium in Wistar rats.
Topics: Aldosterone; Animals; Blood Pressure; Brain; Brain Chemistry; Chlorides; Epithelial Sodium Channels; | 2006 |
[Use of spironolactone and indapamide in the treatment of low-renin arterial hypertension].
Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Creatinine; Diuretics; Female; Follow-Up Studies; Hu | 2006 |
Decreased pituitary response to insulin-induced hypoglycaemia in young lean male patients with essential hypertension.
Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Case-Control Studies; Epinephrine; Growth Hormone | 2006 |
Laparoscopic adrenalectomy for primary hyperaldosteronism: clinical experience with 60 cases.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aged, 80 and over; Aldosterone; Blood | 2006 |
[Blood pressure elevation in obese descendants of parents with essential arterial hypertension and its relation to the renin-angiotensin axis, C-reactive protein, and saline taste sensitivity].
Topics: Adolescent; Adult; Aldosterone; C-Reactive Protein; Child; Child, Preschool; Chlorides; Diastole; Fe | 2006 |
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper | 2006 |
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper | 2006 |
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper | 2006 |
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper | 2006 |
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper | 2006 |
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper | 2006 |
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper | 2006 |
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper | 2006 |
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper | 2006 |
Differential regional haemodynamic changes during mineralocorticoid hypertension.
Topics: Aldosterone; Animals; Antidiuretic Hormone Receptor Antagonists; Cardiac Output; Coronary Circulatio | 2006 |
Confirmatory testing in normokalaemic primary aldosteronism: the value of the saline infusion test and urinary aldosterone metabolites.
Topics: Adult; Aldosterone; False Negative Reactions; Female; Humans; Hyperaldosteronism; Hypertension; Hypo | 2006 |
Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Body | 2006 |
The antagonism of aldosterone receptor prevents the development of hypertensive heart failure induced by chronic inhibition of nitric oxide synthesis in rats.
Topics: Actins; Aldosterone; Animals; Blotting, Western; Cytochrome P-450 CYP11B2; Drug Therapy, Combination | 2006 |
Effects of adrenomedullin on cardiac oxidative stress and collagen accumulation in aldosterone-dependent malignant hypertensive rats.
Topics: Adrenomedullin; Aldosterone; Animals; Blood Pressure; Cardiotonic Agents; Collagen; Fibronectins; He | 2006 |
Osteopontin and carotid atherosclerosis in patients with essential hypertension.
Topics: Adult; Aged; Aldosterone; Atherosclerosis; Biomarkers; Carotid Artery Diseases; Carotid Artery, Comm | 2006 |
[Association of aldosterone synthase gene -344T/C polymorphism with plasma aldosterone and angiotensin II concentration in hypertensive patients].
Topics: Aged; Aldosterone; Angiotensin II; Cytochrome P-450 CYP11B2; Female; Gene Frequency; Genotype; Human | 2006 |
Plasma aldosterone assays: comparison between chemiluminescence-based and RIA methods.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Luminescent Measurements; Plasma; Radioimmuno | 2006 |
Aldosterone, dietary salt, and renal disease.
Topics: Albuminuria; Aldosterone; Animals; Cross-Sectional Studies; Humans; Hyperaldosteronism; Hypertension | 2006 |
Insulin sensitivity in patients with primary aldosteronism: a follow-up study.
Topics: Aldosterone; Antihypertensive Agents; Blood Glucose; Blood Pressure; C-Reactive Protein; Female; Glu | 2006 |
Estrogen and salt sensitivity in the female mRen(2). Lewis rat.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Estrogens; Female; Gene Expressi | 2006 |
The prevalence of a raised aldosterone-renin ratio (ARR) among new referrals to a hypertension clinic.
Topics: Adult; Aged; Aldosterone; Ambulatory Care Facilities; Antihypertensive Agents; Blood Pressure Monito | 2006 |
The liquorice effect on the RAAS differs between the genders.
Topics: Adult; Aldosterone; Blood Pressure; Case-Control Studies; Female; Glycyrrhiza; Humans; Hypertension; | 2006 |
Effects of alcohol withdrawal on blood pressure in hypertensive heavy drinkers.
Topics: Adult; Aldosterone; Analysis of Variance; Biomarkers; Blood Pressure; Catecholamines; Central Nervou | 2006 |
High frequency of primary hyperaldosteronism among hypertensive patients from a primary care area in Sweden.
Topics: Aged; Aldosterone; Fludrocortisone; Humans; Hyperaldosteronism; Hypertension; Middle Aged; Renin; Sw | 2006 |
Mineralocorticoid-receptor blockade, hypertension and heart failure.
Topics: Aldosterone; Clinical Trials as Topic; Eplerenone; Heart Failure; Hormone Antagonists; Humans; Hyper | 2005 |
Diagnosis of adenomatous primary aldosteronism in a patient with severe hypertension.
Topics: Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Algorithms; Humans; Hyperaldosteronism; | 2005 |
Increased aldosterone/renin quotient in obese hypertensive women: a novel role for low-density lipoproteins?
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Blood Glucose; Cells, Cultured; Female; Humans | 2006 |
Sanguinarine downregulates AT1a gene expression in a hypertensive rat model.
Topics: Aldosterone; Alkaloids; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypert | 2006 |
A WNK in the kidney controls blood pressure.
Topics: Aldosterone; Animals; Biological Transport; Blood Pressure; Humans; Hypertension; Kidney; Protein Se | 2006 |
Eplerenone relieves spironolactone-induced painful gynaecomastia in a patient with primary aldosteronism.
Topics: Administration, Oral; Aldosterone; Clinical Trials as Topic; Eplerenone; Gynecomastia; Humans; Hyper | 2007 |
Cholecalciferol treatment changes urinary sodium-potassium ratio and plasma aldosterone of spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Cholecalciferol; Disease Models, Animal; Hypertension; Potassi | 2007 |
The renal physiology of pendrin (SLC26A4) and its role in hypertension.
Topics: Absorption; Acid-Base Equilibrium; Aldosterone; Animals; Anion Transport Proteins; Bicarbonates; Blo | 2006 |
Functional effects of genetic variants in the 11beta-hydroxylase (CYP11B1) gene.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Animals; Biological Assay; Case-Control Stu | 2006 |
Primary hyperaldosteronism in a patient with end-stage renal disease.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Follow-Up Studies; Fosinopril | 2007 |
Plasma aldosterone in hypertensive patients on chronic hemodialysis: distribution, determinants and impact on survival.
Topics: Aged; Aldosterone; Cause of Death; Female; Follow-Up Studies; Health Status; Humans; Hypertension; M | 2006 |
Aldosterone as a key mediator of the cardiometabolic syndrome in primary aldosteronism: an observational study.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Blood Glucose | 2007 |
Aldosterone and cardiovascular disease: smoke and fire.
Topics: Aldosterone; Cardiovascular Diseases; Electrocardiography; Humans; Hyperaldosteronism; Hypertension; | 2006 |
Association of adrenal steroids with hypertension and the metabolic syndrome in blacks.
Topics: Adolescent; Adult; Aldosterone; Black People; Female; Humans; Hydrocortisone; Hypertension; Male; Me | 2007 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen | 2006 |
[MEN type I presenting hypokalemia and hypertension, complicated with acromegaly, adrenal cortical tumor and rectal carcinoid tumor].
Topics: Acromegaly; Adrenalectomy; Adrenocortical Adenoma; Aged; Aldosterone; Carcinoid Tumor; Female; Growt | 2006 |
Reactive oxygen species-dependent hypertension in dopamine D2 receptor-deficient mice.
Topics: Aldosterone; Animals; Antioxidants; Blood Pressure; Hypertension; Mice; Oxidants; Oxidative Stress; | 2007 |
Abnormally increased endothelin-1 in plasma during the night in obstructive sleep apnea: relation to blood pressure and severity of disease.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitori | 2007 |
Apparent mineralocorticoid excess manifested in an elderly patient with hypothyroidism.
Topics: Aged, 80 and over; Aldosterone; Female; Humans; Hypertension; Hypokalemia; Hypothyroidism; Mineraloc | 2007 |
Loss of Vav2 proto-oncogene causes tachycardia and cardiovascular disease in mice.
Topics: Adrenal Glands; Aldosterone; Animals; Aorta; Endothelins; Gene Expression Regulation; Guanine Nucleo | 2007 |
Gender differences in selected zinc metabolism parameters in patients with mild primary arterial hypertension.
Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidas | 2006 |
Hypertension associated with rhabdomyolysis.
Topics: Adult; Aldosterone; Blood Pressure; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hyp | 2007 |
[New concepts in searching for primary aldosteronism in hypertension: advances in screening, confirming and subtyping tests].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Renin; Renin-Angiotensin Syst | 2006 |
[Aldosterone-to-renin ratio threshold for screening primary aldosteronism in Chinese hypertensive patients].
Topics: Adult; Aged; Aldosterone; China; Clinical Chemistry Tests; Female; Humans; Hyperaldosteronism; Hyper | 2006 |
[Aldosterone/plasma renin activity ratio is a sensitive parameter for screening patients with primary aldosteronism].
Topics: Aldosterone; Clinical Chemistry Tests; Follow-Up Studies; Humans; Hyperaldosteronism; Hypertension; | 2006 |
Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: the possible role of local renin-angiotensin system.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Bipheny | 2007 |
Interactions between aldosterone and connective tissue growth factor in vascular and renal damage in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Aorta; Blood Pressure; Blood Pressure Determination; Cells, Cultured; Connecti | 2007 |
[Causes of delaying diagnosis of primary hyperaldosteronism with adrenal adenoma and strategy therefore].
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Biomarkers, Tumor; Chymo | 2006 |
Plasma aldosterone is related to severity of obstructive sleep apnea in subjects with resistant hypertension.
Topics: Adult; Aged; Aldosterone; Case-Control Studies; Female; Humans; Hypertension; Male; Middle Aged; Pol | 2007 |
Clinical and genetic correlates of aldosterone-to-renin ratio and relations to blood pressure in a community sample.
Topics: Aged; Aldosterone; Blood Pressure; Chromosomes, Human, Pair 11; Female; Genetic Linkage; Genetic Var | 2007 |
Polymorphism of CYP11B2 determines salt sensitivity in Japanese.
Topics: Aged; Aldosterone; Asian People; Blood Pressure; Cohort Studies; Cysteine; Cytochrome P-450 CYP11B2; | 2007 |
Aldosterone antagonists: silver bullet or just sodium excretion and potassium retention?
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Huma | 2007 |
Role of aldosterone in left ventricular hypertrophy among African-American patients with end-stage renal disease on hemodialysis.
Topics: Aged; Aldosterone; Black or African American; Diabetes Mellitus; Humans; Hypertension; Hypertrophy, | 2007 |
Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiac Output, Low; | 2007 |
Hypertension caused by prenatal testosterone excess in female sheep.
Topics: Aldosterone; Animals; Blood Pressure; Chlorides; Cholesterol; Disease Models, Animal; Dyslipidemias; | 2007 |
Analysis of renin-angiotensin-aldosterone system gene polymorphisms in resistant hypertension.
Topics: Aldosterone; Brazil; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease | 2007 |
Enhancement of receptor-operated cation current and TRPC6 expression in arterial smooth muscle cells of deoxycorticosterone acetate-salt hypertensive rats.
Topics: Aldosterone; Animals; Aorta; Arteries; Blood Pressure; Blotting, Western; Calcium Channels; Desoxyco | 2007 |
Peroxisome proliferator-activated receptor alpha-independent actions of fenofibrate exacerbates left ventricular dilation and fibrosis in chronic pressure overload.
Topics: Aldosterone; Animals; Cells, Cultured; Chronic Disease; Extracellular Signal-Regulated MAP Kinases; | 2007 |
WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.
Topics: Aldosterone; Animals; Colon; Epithelial Sodium Channels; Hyperkalemia; Hypertension; Mice; Mice, Tra | 2007 |
CYP3A5 and ABCB1 genes influence blood pressure and response to treatment, and their effect is modified by salt.
Topics: Absorption; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; ATP Binding Cassette Trans | 2007 |
Possibly simultaneous primary aldosteronism and preclinical Cushing's syndrome in a patient with double adenomas of right adrenal gland.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cushing Syndrome; Enzymes; Female; Humans; Hydrocorti | 2007 |
Urinary free cortisol is not a biochemical marker of hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adult; Aged; Aldosterone; Biomarkers; Blood Pressure; C | 2007 |
Evolution and hypertension: is the Renin system necessary?
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angi | 2007 |
Aldosteronism: too much of a good thing. The hormone aldosterone helps the body manage water and sodium. Too much of it is an overlooked cause of high blood pressure.
Topics: Adrenal Gland Diseases; Adrenal Glands; Aldosterone; Body Water; Humans; Hyperaldosteronism; Hyperte | 2007 |
[Association of aldosterone synthase gene -344 T/C polymorphism with early renal damage in Han nationality with essential hypertension].
Topics: Adult; Albumins; Albuminuria; Aldosterone; Asian People; China; Cytochrome P-450 CYP11B2; Female; Ge | 2007 |
Left ventricular hypertrophy and geometry in untreated essential hypertension is associated with blood levels of aldosterone and procollagen type III amino-terminal peptide.
Topics: Aldosterone; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Linear M | 2007 |
Developmental activity of the renin-angiotensin system during the "critical period" modulates later L-NAME-induced hypertension and renal injury.
Topics: Aging; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles | 2007 |
Prevalence of primary aldosteronism among unselected hypertensive patients: a prospective study based on the use of an aldosterone/renin ratio above 25 as a screening test.
Topics: Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Mass Screening; Mi | 2007 |
Differential aerobic exercise-induced changes in plasma aldosterone between African Americans and Caucasians.
Topics: Abdominal Fat; Aged; Aldosterone; Black or African American; Blood Pressure; Exercise; Female; Human | 2007 |
Arterial plasma vasopressin and aldosterone predict left ventricular mass in men who develop hypertension over 20 years.
Topics: Adult; Aldosterone; Analysis of Variance; Antihypertensive Agents; Arteries; Biomarkers; Blood Press | 2007 |
[Conn syndrome].
Topics: Aldosterone; Causality; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypernatremia; Hyperten | 2007 |
The incidentally discovered adrenal mass.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Black People; Humans; Hyperaldosteron | 2007 |
[Determining aldosterone in the adrenal veins in order to establish uni- or bilateral aldosterone production in patients with primary hyperaldosteronism].
Topics: Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Male; | 2007 |
Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation.
Topics: Aldosterone; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Body Weight; Cytokines; | 2007 |
Primary hyperaldosteronism: returning to the limelight?
Topics: Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 2007 |
Unilateral adrenal hyperplasia.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; R | 2007 |
[Primary aldosteronism caused by aldosteronoma: problems in the etiologic diagnosis].
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Diagnosis, Differential; Fem | 2007 |
Synergistic induction of osteopontin by aldosterone and inflammatory cytokines in mesangial cells.
Topics: Aldosterone; Animals; Chemotaxis, Leukocyte; Drug Synergism; Hypertension; Interleukin-1beta; Mesang | 2008 |
The influence of serum aldosterone and the aldosterone-renin ratio on pulse wave velocity in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Lipids; Mid | 2007 |
Renal cysts and hypokalemia in primary aldosteronism: results of long-term follow-up after treatment.
Topics: Adrenalectomy; Aldosterone; Follow-Up Studies; Humans; Hyperaldosteronism; Hypertension; Hypokalemia | 2007 |
Insulin resistance and hyperinsulinemia are related to plasma aldosterone levels in hypertensive patients.
Topics: Aged; Aldosterone; Cross-Sectional Studies; Female; Glucose; Humans; Hyperinsulinism; Hypertension; | 2007 |
Polycystic ovary syndrome: implications of corticotropin in the regulation of blood pressure, aldosterone, and androgen secretion.
Topics: Adrenocorticotropic Hormone; Aldosterone; Biomarkers; Blood Pressure; Female; Humans; Hypertension; | 2007 |
Captopril test can give misleading results in patients with suspect primary aldosteronism.
Topics: Aldosterone; Captopril; Clinical Laboratory Techniques; Cohort Studies; Female; Humans; Hyperaldoste | 2007 |
A polymorphic GT short tandem repeat affecting beta-ENaC mRNA expression is associated with low renin essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Case-Control Studies; Chile; Dinucleotide Repeats; Epithelial So | 2007 |
Effects of fenofibrate on cardiac remodeling in aldosterone-induced hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Extracellular Matrix; Fenofibrate; Fibrosis; Heart; Heart Rate | 2007 |
Aldosterone causes vasoconstriction in coronary arterioles of rats via angiotensin II type-1 receptor: influence of hypertension.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Coronary Vessels; Endothe | 2007 |
Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study.
Topics: Adrenocorticotropic Hormone; Aged; Aldosterone; Alleles; Cortodoxone; Cytochrome P-450 CYP11B2; Fema | 2007 |
The effect of diet on simvastatin and losartan enhancement of endothelial function.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Diet; | 2007 |
Tailored hormonal therapy in secretory adrenocortical cancer.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Aldosterone; Alkalosis; Ang | 2007 |
Is there an unrecognized epidemic of primary aldosteronism? Con.
Topics: Adrenal Gland Neoplasms; Aldosterone; Disease Outbreaks; Humans; Hyperaldosteronism; Hypertension; I | 2007 |
Resistant hypertension: a methodological approach to diagnosis and treatment.
Topics: Aldosterone; Diagnosis, Differential; Drug Resistance; Humans; Hyperaldosteronism; Hypertension; Pat | 2007 |
A comparative study of plasma renin activity, aldosterone and atrial natriuretic hormone between normotensive and hypertensive people living at below sea level altitude (Jordan Valley) and those residing at moderate altitude above.
Topics: Adult; Aged; Aldosterone; Altitude; Atrial Natriuretic Factor; Cross-Sectional Studies; Health Surve | 2007 |
Associations between sympathetic activity, plasma concentrations of renin, aldosterone, and parathyroid hormone, and the degree of intractability of blood pressure control in modialysis patients.
Topics: Adult; Aged; Aldosterone; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Epinephrine | 2007 |
Unexpected therapeutic response to spironolactone: a prospective debate on aldosterone and potassium ion in hypertension.
Topics: Aldosterone; Dose-Response Relationship, Drug; Humans; Hypertension; Potassium; Renin-Angiotensin Sy | 2007 |
Determination of the aldosterone/renin ratio in 269 patients with adrenal incidentaloma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Blood Pressure; Female; Humans; Hyperten | 2007 |
Increased plasma aldosterone-to-renin ratio is associated with impaired left ventricular longitudinal functional reserve in patients with uncomplicated hypertension.
Topics: Aldosterone; Exercise Test; Female; Fractional Flow Reserve, Myocardial; Humans; Hypertension; Male; | 2008 |
Antenatal and postnatal risk factors for neonatal hypertension and infant follow-up.
Topics: Aldosterone; Australia; Birth Weight; Blood Pressure; Body Height; Female; Follow-Up Studies; Gestat | 2007 |
Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: role of oxidative stress.
Topics: Aldosterone; Animals; Antioxidants; Cyclic N-Oxides; Disease Models, Animal; Eplerenone; Hypertensio | 2007 |
Sympathoadrenergic and metabolic factors are involved in ambulatory blood pressure rise in childhood obesity.
Topics: Adolescent; Albuminuria; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Ma | 2008 |
Resistant hypertension and aldosterone excess: new insights from ambulatory blood pressure monitoring.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Drug Resistance; Humans | 2007 |
A possible association between primary aldosteronism and a lower beta-cell function.
Topics: Aged; Aldosterone; Blood Glucose; C-Peptide; Case-Control Studies; Cholesterol; Female; Humans; Hype | 2007 |
Aldosterone excess and resistance to 24-h blood pressure control.
Topics: Adult; Age Factors; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monit | 2007 |
Long-term cardiac effects of adrenalectomy or mineralocorticoid antagonists in patients with primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Female; Follo | 2007 |
Rapid cortisol assay during adrenal vein sampling in patients with primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Female; Humans; Hydrocortisone | 2007 |
Insulin resistance and hyperinsulinemia are related to plasma aldosterone levels in hypertensive patients: response to Colussi et al.
Topics: Aldosterone; Humans; Hyperinsulinism; Hypertension; Insulin; Insulin Resistance; Reproducibility of | 2007 |
Effects of aldosterone and angiotensin II receptor blockade on cardiac angiotensinogen and angiotensin-converting enzyme 2 expression in Dahl salt-sensitive hypertensive rats.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensinog | 2007 |
Increased expression in calcitonin-like receptor induced by aldosterone in cerebral arteries from spontaneously hypertensive rats does not correlate with functional role of CGRP receptor.
Topics: Aldosterone; Animals; Calcitonin Receptor-Like Protein; Cerebral Arteries; Hypertension; Intracellul | 2008 |
Absence of peroxisome proliferator-activated receptor-alpha abolishes hypertension and attenuates atherosclerosis in the Tsukuba hypertensive mouse.
Topics: Aldosterone; Angiotensin II; Animals; Atherosclerosis; Blood Pressure; Cardiomegaly; Diet, Atherogen | 2007 |
[Comparison of adrenal imaging and selective adrenal vein sampling in primary hyperaldosteronism].
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Female; Humans; Hydro | 2007 |
[Hypokalemic hypertension cause by licorice abuse].
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Diagnosis, Differential; Female; Glycyrrhi | 2007 |
Neuroendocrine profiling in inherited stress-induced arterial hypertension rat strain with stress-sensitive arterial hypertension.
Topics: Adrenal Cortex; Adrenal Medulla; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure; | 2007 |
Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome.
Topics: Aldosterone; Animals; Colon; Disease Models, Animal; Epithelial Sodium Channels; Female; Hypertensio | 2008 |
More fuel to the debate on the "epidemics of primary aldosteronism".
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Captopril; Humans; Hyperaldosteronism; Hyperte | 2008 |
A not-so-modest proposal that a "modest" increase in aldosterone causes hypertension and more.
Topics: Aldosterone; Animals; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Mice; Renin; Sodium | 2008 |
Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cytochrome P-450 CYP11B2; Female; Hyperaldoste | 2008 |
The aldosterone to renin ratio in the evaluation of patients with incidentally detected adrenal masses.
Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Case-Control Studies; Diagnosis, Differential; Fema | 2007 |
Adrenocortical changes and arterial hypertension in lipoatrophic A-ZIP/F-1 mice.
Topics: Adipokines; Adipose Tissue, White; Adrenal Cortex; Aldosterone; Animals; Blood Glucose; Blood Pressu | 2008 |
Prospective evaluation and characteristics of patients with suspected primary hyperaldosteronism.
Topics: Adult; Aldosterone; Body Mass Index; Female; Glucose Intolerance; Humans; Hyperaldosteronism; Hypert | 2007 |
An additional child case of an aldosterone-producing adenoma with an atypical presentation of peripheral paralysis due to hypokalemia.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Aldosterone; Female; Humans; Hyperaldosteronism; Hyper | 2007 |
Relation of dietary salt and aldosterone to urinary protein excretion in subjects with resistant hypertension.
Topics: Aged; Aldosterone; Circadian Rhythm; Cohort Studies; Female; Humans; Hypertension; Male; Middle Aged | 2008 |
A novel adipokine CTRP1 stimulates aldosterone production.
Topics: Adipokines; Aldosterone; Angiotensin II; Animals; Calcium; Cytochrome P-450 CYP11B2; DNA-Binding Pro | 2008 |
Plasma potassium level is associated with common genetic variation in the beta-subunit of the epithelial sodium channel.
Topics: Adult; Aldosterone; Alleles; Blood Pressure; DNA; Epithelial Sodium Channels; Female; Heterozygote; | 2008 |
Cardiovascular outcomes in patients with primary aldosteronism after treatment.
Topics: Adrenalectomy; Adult; Aged; Aldosterone; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; | 2008 |
Increased nocturnal sodium excretion in obstructive sleep apnoea. Relation to nocturnal change in diastolic blood pressure.
Topics: Adult; Age Factors; Aldosterone; Aquaporin 2; Arginine Vasopressin; Atrial Natriuretic Factor; Blood | 2008 |
Diastolic dysfunction is associated with insulin resistance, but not with aldosterone level in normotensive offspring of hypertensive families.
Topics: Adult; Aldosterone; Case-Control Studies; Female; Genetic Predisposition to Disease; Heart Failure, | 2008 |
Letter regarding article by Hood et al, "The Spironolactone, Amiloride, Losartan, and Thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio".
Topics: Aldosterone; Amiloride; Antihypertensive Agents; Bendroflumethiazide; Cross-Over Studies; Double-Bli | 2008 |
Aldosterone and hypertension in the cardiometabolic syndrome.
Topics: Aldosterone; Body Mass Index; Humans; Hyperaldosteronism; Hypertension; Metabolic Syndrome; Risk Fac | 2008 |
RNAi inhibition of mineralocorticoid receptors prevents the development of cold-induced hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Cardiomegaly; Cold Temperature; Dependovirus; Dis | 2008 |
Translational research goes both ways: lessons from clinical studies.
Topics: Aldosterone; Amino Acid Sequence; Antihypertensive Agents; Biomedical Research; Clinical Trials as T | 2008 |
Urinary kallikrein and blood pressure--gender-different response to potassium supplementation in SHR. Role of aldosterone.
Topics: Aldosterone; Animals; Blood Pressure; Female; Hypertension; Kallikreins; Male; Potassium, Dietary; R | 2008 |
Relationship between oxidative stress and essential hypertension.
Topics: Adult; Aldosterone; Ascorbic Acid; Blood Pressure; Cross-Sectional Studies; Dinoprost; Endothelin-1; | 2007 |
Vascular remodeling and duration of hypertension predict outcome of adrenalectomy in primary aldosteronism patients.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Arteries; Blo | 2008 |
Heart rate variability in white-coat hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensins; Arginine Vasopressin; Autonomic Nervous System; Blood Pressu | 2008 |
Low renin hypertension (LRH): shades of John Laragh.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 2008 |
The antihypertensive effects of quercetin in a salt-sensitive model of hypertension.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dimethyl Sulfoxide; Diseas | 2008 |
The in vivo effects of Tulbhagia violacea on blood pressure in a salt-sensitive rat model.
Topics: Aldosterone; Animals; Blood Pressure; Heart Rate; Hypertension; Liliaceae; Male; Phytotherapy; Plant | 2008 |
[Is there an unrecognized epidemic of primary aldosteronism? The Danish Society of Hypertension].
Topics: Aldosterone; Denmark; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Prevalence; Renin | 2008 |
Plasma and urine aldosterone to plasma renin activity ratio in the diagnosis of primary aldosteronism.
Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Predictive Value o | 2008 |
Urinary aldosterone-to-active-renin ratio: a useful tool for predicting resolution of hypertension after adrenalectomy in patients with aldosterone-producing adenomas.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Age Factors; Aged; Aldosterone; Antihyperten | 2008 |
Body mass index predicts plasma aldosterone concentrations in overweight-obese primary hypertensive patients.
Topics: Aldosterone; Body Mass Index; Female; Humans; Hypertension; Male; Middle Aged; Obesity; Overweight; | 2008 |
High blood pressure arising from a defect in vascular function.
Topics: Aldosterone; Animals; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinas | 2008 |
High plasma aldosterone and low renin predict blood pressure increase and hypertension in middle-aged Caucasian populations.
Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Female; Follow-Up Studies; France; Humans; Hyperten | 2008 |
Significance of angiotensinogen gene haplotypes and genotypes combinations in hypertension.
Topics: Adult; Aldosterone; Angiotensinogen; Case-Control Studies; Female; Genotype; Haplotypes; Humans; Hyp | 2008 |
Crosstalk between the heme oxygenase system, aldosterone, and phospholipase C in hypertension.
Topics: Aldosterone; Animals; Aorta; Blood Pressure; Calcium; Cyclic GMP; Cyclic GMP-Dependent Protein Kinas | 2008 |
Upregulation of apical sodium-chloride cotransporter and basolateral chloride channels is responsible for the maintenance of salt-sensitive hypertension.
Topics: Aldosterone; Animals; Chloride Channels; Chloride-Bicarbonate Antiporters; Disease Models, Animal; E | 2008 |
ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit.
Topics: Adrenergic beta-Agonists; Adrenocorticotropic Hormone; Aldosterone; Animals; Binding Sites; Blood Pr | 2008 |
Effects of mannooligosaccharides from coffee mannan on blood pressure in Dahl salt-sensitive rats.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Coffee; Diet; Disease Models, Animal; Hypertensio | 2008 |
Central infusion of aldosterone synthase inhibitor prevents sympathetic hyperactivity and hypertension by central Na+ in Wistar rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Brain; Corticosterone; Cytochrome P-450 CYP11B | 2008 |
A new form of congenital adrenal hyperplasia.
Topics: Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Aldosterone; | 1967 |
Heart failure in the elderly.
Topics: Aged; Aldosterone; Aminophylline; Digitalis; Diuretics; Heart Failure; Humans; Hypertension; Organom | 1967 |
Independence of blood pressure and aldosterone secretion.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Guanethidine; Humans; Hyperaldosteronism | 1967 |
Bilateral adrenal hyperplasia as a cause of primary aldosteronism with hypertension, hypokalemia and suppressed renin activity.
Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenal Glands; Aldosterone; Blood Urea Nitrogen; | 1967 |
The steroid content of adrenal adenomas and measurements of aldosterone production in patients with essential hypertension and primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Corticosterone; Female; Humans; Hydrocor | 1967 |
Salivary electrolytes, urea nitrogen, uric acid and salt taste thresholds in hypertension.
Topics: Aldosterone; Chlorine; Citrates; Humans; Hypertension; Parotid Gland; Potassium; Saliva; Secretory R | 1967 |
Hypertension and hypokalemic alkalosis associated with underproduction of aldosterone.
Topics: Adrenal Glands; Aldosterone; Alkalosis; Blood Pressure Determination; Child; Diagnosis, Differential | 1967 |
Hypokalemia in the hypertensive patient, with observations on the incidence of primary aldosteronism.
Topics: Aldosterone; Benzothiadiazines; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Potassium; Re | 1967 |
Hypertension following subcutaneous and intraperitoneal injections of polyvinyl alcohol and the effect of aldosterone.
Topics: Alcohols; Aldosterone; Animals; Arteritis; Blood Pressure; Body Weight; Female; Hepatomegaly; Hypert | 1967 |
Childhood primary aldosteronism with bilateral adrenocortical hyperplasia: plasma renin activity as an aid to diagnosis.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Child; Child, Preschool; Humans; Hyperaldosteronism; Hyp | 1967 |
Primary aldosteronism: case report with plasma renin suppression.
Topics: Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension; Hypok | 1967 |
Experimental hypertensive disease of pregnancy.
Topics: Aldosterone; Angiography; Animals; Blood Pressure; Dogs; Female; Fetus; Hypertension; Kidney; Matern | 1967 |
Effect of diazoxide on plasma renin activity in hypertensive patients.
Topics: Aldosterone; Blood Glucose; Blood Pressure; Creatinine; Diazoxide; Diet; Humans; Hypertension; Natri | 1967 |
[On the diagnosis of Conn's syndrome].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Renin | 1967 |
A quantitative gas-liquid chromatographic method for aldosterone in human urine.
Topics: Aldosterone; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Humans; Hyperaldosteronism | 1967 |
[Electrolyte metabolism in hypertension].
Topics: Adult; Aged; Aldosterone; Animals; Catecholamines; Diet; Female; Food; Humans; Hydrochlorothiazide; | 1967 |
The comparative hypertensive activities of the acetates of D-aldosterone and deoxycorticosterone.
Topics: Acetates; Aldosterone; Animals; Desoxycorticosterone; Female; Heart; Hypertension; Kidney; Myocardiu | 1967 |
Oral contraceptives. Renin, aldosterone, and high blood pressure.
Topics: Adult; Aldosterone; Blood Pressure; Contraceptives, Oral; Female; Humans; Hypertension; Middle Aged; | 1967 |
Pregnancy and primary aldosteronism.
Topics: Adult; Aldosterone; Carbon Dioxide; Chlorides; Female; Humans; Hyperaldosteronism; Hypertension; Pot | 1967 |
[Renin-angiotensin-aldosterone system in hypertensive conditions].
Topics: Adult; Aged; Aldosterone; Female; Fundus Oculi; Humans; Hypertension; Hypertension, Malignant; Hyper | 1967 |
[Use of the method of determination of tetrahydroaldosterone in the study of clinical cases].
Topics: Adolescent; Adult; Aldosterone; Child, Preschool; Female; Humans; Hyperaldosteronism; Hypertension; | 1967 |
Renal effects of nitrendipine monotherapy in essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Volume; Calcium Channel Blockers; Cardiac Output; Epinephrine; Glome | 1984 |
The calcium channel blocker nitrendipine in single- and multiple-agent antihypertensive regimens: preliminary report of a multicenter study.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Calcium Channel Blockers; Drug Therapy, Combi | 1984 |
Clinical and experimental studies on human urinary angiotensin I-converting enzyme.
Topics: Aldosterone; Electrolytes; Humans; Hypertension; Kinetics; Molecular Weight; Peptidyl-Dipeptidase A; | 1984 |
Hormonal and metabolic effects of angiotensin converting enzyme inhibitors. Possible differences between enalapril and captopril.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dip | 1984 |
Enalapril in treatment of hypertension with renal artery stenosis. Changes in blood pressure, renin, angiotensin I and II, renal function, and body composition.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Body Compos | 1984 |
Renal Na+-K+-ATPase in weanling and adult spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Hypertension; Kidney; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-A | 1984 |
[Changes in responses of blood pressure and several hormones to infusions of angiotensin II and angiotensin III in patients with essential hypertension].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Angiotensin III; Blood Pressure; Ca | 1984 |
Influence of chronic renal failure on captopril pharmacokinetics and clinical and biological effects in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Femal | 1984 |
Effects of prostacyclin on the responses of blood pressure and several hormones in normotensive and hypertensive subjects.
Topics: Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Epinephrine; Epoprostenol; Hormones; Human | 1984 |
[Effect of ACTH on serum corticosteroid level in patients with hypertension].
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hyp | 1984 |
Plasma enalapril levels and hormonal effects after short- and long-term administration in essential hypertension.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bloo | 1984 |
Altered corticosteroid control of the erythrocyte sodium-potassium pump in the spontaneously hypertensive rat.
Topics: Adenosine Triphosphatases; Adrenal Cortex Hormones; Adrenalectomy; Aldosterone; Animals; Dexamethaso | 1983 |
Volume control and altered renal and adrenal responsiveness to angiotensin in essential hypertension: implications for treatment with converting enzyme inhibition.
Topics: Adrenal Glands; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bloo | 1983 |
Physiological effects of short-term treatment with enalapril in hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Dose-Response Relationship, Drug; Enalapril; Epinephrine; Female | 1983 |
Clinical pharmacology of enalapril.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biological Ava | 1984 |
Converting enzyme inhibitors normalize the reduced adrenal responsiveness to angiotensin II in essential hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressur | 1984 |
Beta-adrenergic regulation of circadian rhythmicity of the renin-angiotensin-aldosterone system in five subtypes of essential hypertension.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Circadian Rhythm; Femal | 1980 |
Low-dose diuretic and beta adrenoceptor blocker in essential hypertension.
Topics: Adrenergic beta-Antagonists; Aldosterone; Analysis of Variance; Black People; Blood Pressure; Diuret | 1980 |
Angiotensin II blockade during combined thiazide-beta-blocker treatment.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Drug Interactions; Female; Humans; | 1980 |
[Neurohumoral regulation problems and the pathogenesis of hypertension].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Blood Pressure; Homeostasis; Humans; Hypertension; Neur | 1980 |
Prizidilol, an antihypertensive with precapillary vasodilator and beta-adrenoceptor blocking actions, in primary hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Antihypertensive Agents; Drug Evaluation; Fem | 1981 |
Antihypertensive effect of the new oral angiotensin converting enzyme inhibitor "MK-421".
Topics: Administration, Oral; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibi | 1981 |
Net influx and efflux of 22Na in erythrocytes from normotensive offspring of patients with essential hypertension.
Topics: Adult; Aldosterone; Biological Transport; Erythrocytes; Female; gamma-Glutamyltransferase; Humans; H | 1981 |
Neurohumoral response to hospitalization in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Epinephrine; Hospitalization; Humans; Hypertension; Middle | 1981 |
Biochemistry and pharmacology of hypertension.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Brain; Homeostasis; Humans; Hypertension; | 1982 |
Prizidilol (SK & F 92657), a new vasodilator with beta-blocking properties in the treatment of essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Pressure; Female; Heart Rate; Humans; H | 1982 |
[Mineralocorticoid function of the adrenal glands in adolescents with primary arterial hypertension before and after treatment with beta-blocking agents].
Topics: Administration, Oral; Adolescent; Adrenal Cortex; Adrenergic beta-Antagonists; Aerosols; Aldosterone | 1983 |
The role of prostaglandins in the regulation of blood pressure with special reference to vascular reactivity.
Topics: Adult; Aldosterone; Alprostadil; Animals; Blood Pressure; Humans; Hypertension; Indomethacin; Male; | 1984 |
[Etiological studies of hypertension. A Renin-angiotension-aldosterone system].
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Humans; Hypertension; Middle Aged; Renin; Renin-Ang | 1984 |
Treatment of drug-resistant hypertension with minoxidil or angiotensin-converting enzyme inhibitor: blood pressure, renin, aldosterone, and electrolyte responses.
Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Captopril; Creatinine; Drug Resistance; Female; Hum | 1980 |
Increased aldosterone metabolic clearance in hypertensive patients treated with minoxidil: an effect of greater hepatic perfusion.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Diuretics; Humans; Hypertension; Indocyanine Green; Liver; | 1980 |
Angiotensin-converting enzyme inhibitors.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Heart Failure; Hum | 1980 |
Altered blood pressure and renin responses to converting enzyme inhibition after aprotinin-induced kallikrein-kinin-system blockade.
Topics: Aldosterone; Angiotensin II; Aprotinin; Blood Pressure; Captopril; Humans; Hypertension; Peptidyl-Di | 1980 |
[Aldosterone content of the blood in ischemic heart disease under antireticular cytotoxic serum treatment].
Topics: Adult; Aldosterone; Coronary Disease; Female; Humans; Hypertension; Immune Sera; Immunization, Passi | 1982 |
Relation of blood pressure and body sodium content during sodium depletion in normal and hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Diuretics; Humans; Hype | 1984 |
Distribution of extracellular fluid over the intra- and extravascular space in hypertensive patients.
Topics: Adenoma; Adult; Aldosterone; Blood Pressure; Blood Volume; Cardiac Output; Extracellular Space; Huma | 1984 |
Forearm vasoconstrictor response to ouabain: studies in patients with mild and moderate essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Epinephrine; Forearm; Humans; Hypertension; Male; Middle A | 1984 |
[A simple diagnostic test for primary hyperaldosteronism].
Topics: Adrenal Glands; Adult; Aldosterone; Captopril; Humans; Hyperaldosteronism; Hyperplasia; Hypertension | 1983 |
The characteristics of renal mineralocorticoid receptors in glycyrrhizinic acid or deoxycorticosterone-induced hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Cytosol; Desoxycorticosterone; Glycyrrhetinic Acid; Glycyrrhiz | 1984 |
[Binding of aldosterone to its receptors along the nephron of the normal and spontaneously hypertensive rat].
Topics: Aldosterone; Animals; Autoradiography; Female; Hypertension; Nephrons; Rats; Rats, Inbred SHR; Rats, | 1984 |
Endocrine and cardiovascular influences of converting enzyme inhibition with SQ 14225 in hypertensive patients in the supine position and during head-up tilt before and after sodium depletion.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Epinephrine | 1980 |
[The long term effect of the oral converting enzyme inhibitor captopril in hypertensive patients (author's transl)].
Topics: Administration, Oral; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Catecholamin | 1980 |
In vitro steroidogenic properties of a new hypertension-producing compound isolated from normal human urine.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Cats; Cyclic AMP; | 1980 |
[Clinical experience with an oral angiotensin I-converting enzyme inhibitor in hypertensive patients: effects on blood pressure and the renin-aldosterone system by a single dose (author's transl)].
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; | 1980 |
Chronic ACTH administration and the development of hypertension in rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure; Blood Volume; Corticosterone; Des | 1980 |
[Effect of angiotensin converting enzyme inhibitor (SQ 14225) on renin-angiotesin sytem and haemodynamics (author's transl)].
Topics: Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Captopril; Hemodynamics; Human | 1980 |
Renin-angiotensin-aldosterone system.
Topics: Aging; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Humans | 1980 |
Dose response in captopril therapy of hypertension.
Topics: Adult; Aldosterone; Angiotensins; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Femal | 1980 |
Endocrine profile in the long-term phase of converting-enzyme inhibition.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diet, Sodiu | 1980 |
Primary aldosteronism due to unilateral adrenal hyperplasia.
Topics: Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldosterone; Blood Pressur | 1980 |
Aldosterone-induced hypertension: effects of a kininase inhibitor.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Female; H | 1980 |
Sodium-potassium-dependent ATPase activity in erythrocyte ghosts of patients with primary and secondary hypertension.
Topics: Adult; Aldosterone; Cushing Syndrome; Erythrocyte Membrane; Erythrocytes; Female; Humans; Hydrocorti | 1980 |
[The long term effects of the oral converting enzyme inhibitor, captopril in hypertensive patients--the endocrinological study of its hypotensive mechanism (author's transl)].
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Catecholami | 1980 |
Studies on the mechanism of "exaggerated natriuresis" in essential hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Diuresis; Glomerul | 1981 |
Aldosterone response to prolonged ACTH infusion in juvenile hypertension.
Topics: Adolescent; Adrenocorticotropic Hormone; Aldosterone; Child; Humans; Hypertension; Potassium; Renin; | 1980 |
[Captopril in the treatment of essential hypertension (author's transl)].
Topics: Adult; Aldosterone; Anemia; Captopril; Humans; Hypertension; Middle Aged; Peptidyl-Dipeptidase A; Po | 1980 |
Plasma aldosterone and corticosterone responses to adrenocorticotropin, angiotensin, potassium, and stress in spontaneously hypertensive rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Corticosterone; Hypertension; Mal | 1981 |
Captopril in various forms of severe therapy-resistant hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Captopril; Female; Heart Rate; Humans; Hypert | 1981 |
Effects of a single administration of captopril on hemodynamics and serum angiotensin converting enzyme activity, plasma renin activity and plasma aldosterone concentration in hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Cardiac Output; Female; Heart Rate; Hemodynamics; Hum | 1981 |
Intra-erythrocyte sodium and (Na+,K+-activated)-ATPase concentration and urinary aldosterone excretion in spontaneously hypertensive rats.
Topics: Adenosine Triphosphate; Aldosterone; Animals; Erythrocytes; Hypertension; Male; Potassium; Rats; Sod | 1981 |
[Behavior of aldosterone and plasma renin activity after ACTH administration and insulin-induced hypoglycemia in patients with essential arterial hypertension].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Glucose; Humans; Hydrocortisone; Hypertension | 1981 |
Effect of propranolol therapy on aldosterone responses to angiotensin II and adrenocorticotropic hormone in essential hypertension.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Humans; Hypertension; Male; Middle Aged; P | 1981 |
Overproduction of sodium-retaining steroids by the zona glomerulosa is adrenocorticotropin-dependent and mediates hypertension in dexamethasone-suppressible aldosteronism.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Aminoglutethimide; Child, Preschool | 1981 |
Alterations in aldosterone biosynthesis in essential hypertensives.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Humans; Hypertension; Middle Aged; | 1981 |
Hormonal responses to long-term converting enzyme inhibition in hypertensive patients.
Topics: Adolescent; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; | 1981 |
[Changes in blood viscosity concomitant with prazosin therapy in patients with essential arterial hypertension].
Topics: Adult; Aldosterone; Blood Pressure; Blood Viscosity; Creatinine; Female; Heart Rate; Humans; Hyperte | 1980 |
[Lecture: the interrelation between endocrinology and clinical internal medicine (author's transl)].
Topics: Adult; Aldosterone; Angiotensins; Cyclic AMP; Cyclic GMP; Endocrine Glands; Female; Humans; Hyperten | 1981 |
Hypertension, hypokalemia and hypoaldosteronism with suppressed renin: a clinical study of a patient with Liddle's syndrome.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Biological Transport; Diagnosis, Differential; Fema | 1981 |
Decreased adrenal responsiveness to angiotensin II: a defect present in spontaneously hypertensive rats. A possible model of human essential hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Corticosterone; Disease Models, Animal; Female | 1982 |
Pituitary - adrenocortical function in patients during treatment with the angiotensin-converting enzyme inhibitor captopril.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Captopril; Female; Humans; Hydrocortisone; Hyperten | 1981 |
Two cases of low-renin hypertension thought to be due to excessive secretion of unknown mineralocorticoid.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood P | 1982 |
Dexamethasone suppressible hyperaldosteronism in a child with nephrosclerosis.
Topics: Adrenocorticotropic Hormone; Aldosterone; Child; Dexamethasone; Glomerulonephritis; Humans; Hyperald | 1982 |
Converting enzyme inhibition with captopril in patients with primary hyperaldosteronism.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Drug Therapy, Comb | 1982 |
Effects of angiotensin I converting enzyme inhibitor (SQ 14,225) on the responses of blood pressure and steroid hormone to angiotensin II and ACTH infusion in hypertensive subjects.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopr | 1982 |
Prediction of sustained antihypertensive efficacy of chronic captopril therapy: relationships to immediate blood pressure response and control plasma renin activity.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood P | 1982 |
Angiotensin-converting enzyme inhibition, catecholamines and hemodynamics in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Epinephrine | 1982 |
Acute and chronic effects of the angiotensin-converting enzyme inhibitor captopril in severe hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Creatinine; Dose-R | 1982 |
Humoral and hemodynamic effects of increasing doses of captopril in patients with essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Female; Hemodynamic | 1982 |
SA446, a new orally active converting enzyme inhibitor: antihypertensive action and comparison with captopril in stroke-prone spontaneously hypersensitive rats.
Topics: 3-Mercaptopropionic Acid; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypert | 1982 |
The role of steroids in human essential hypertension.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Desoxycorticoster | 1982 |
Effects of enalapril, a new converting enzyme inhibitor, in hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood P | 1982 |
Response of plasma ACTH and adrenocortical hormones to potassium loading in essential hypertension.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldosterone; Desoxycorticosterone; Grow | 1982 |
19-nor-deoxycorticosterone excretion in healthy and hypertensive subjects.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Desoxycorticosterone; Electrolytes; Female; Humans; | 1981 |
[Role of hormonal factors in the development of arterial hypertension in obesity].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Humans; Hypertension; Obesity; Renin; Secretory Rat | 1982 |
17 alpha-hydroxylase deficiency syndrome associated with bilateral streak gonads and impaired development of Müllerian ducts derivatives. Report of a case.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aldosterone; Amenorrhea; C | 1982 |
Exchangeable and total body sodium and potassium in various hypertensive syndromes.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Humans; Hydrocortisone; Hyperaldosteronism | 1982 |
19-hydroxyandrostenedione, a new amplifier of the action of aldosterone, in low renin essential hypertension.
Topics: Addison Disease; Adrenocorticotropic Hormone; Aldosterone; Androstenedione; Cushing Syndrome; Female | 1982 |
Increased excretion of 18-hydroxycorticosterone in patients with adrenal adenomas and hypertension.
Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Aldo | 1982 |
Aldosterone response to antihypertensive treatment.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Atenolol; Blood Pressure; Dipepti | 1982 |
Suppression of adrenal mineralocorticoid production in prehypertensive young adult men.
Topics: 18-Hydroxycorticosterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldosterone; | 1983 |
Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension.
Topics: Adult; Age Factors; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Calcium; Heart Rate; | 1982 |
Specificity of the alteration in aldosterone biosynthesis in the spontaneously hypertensive rat.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Corticosterone; Diet, Sodium-Rest | 1983 |
Participation of the renin system in treatment-resistant hypertension as measured by acute blockade of the angiotensin converting enzyme.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Humans; Hyp | 1982 |
Metabolic and blood pressure responses to hydrocortisone in the syndrome of apparent mineralocorticoid excess.
Topics: Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Child; Female; Humans; Hydrocortisone; Hyd | 1983 |
Cardiovascular, humoral, and renal effects of phenoxybenzamine in hypertension.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Cardiovascular System; Furosemide; Humans; Hypertens | 1983 |
Adrenocortical response to corticotropin is inhibited by gamma 3-MSH antisera in normotensive and spontaneously hypertensive rats.
Topics: 18-Hydroxycorticosterone; Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Animals; Antibod | 1983 |
Volume hormones and blood pressure.
Topics: Aldosterone; Animals; Arginine Vasopressin; Blood Pressure; Blood Volume; Female; Heart Atria; Human | 1983 |
Effects of a new angiotensin-converting enzyme inhibitor, MK 421, in normal men and patients.
Topics: Adult; Aldosterone; Angiotensin I; Antihypertensive Agents; Bartter Syndrome; Blood Pressure; Dipept | 1982 |
Influence of food on the clinical effect of angiotensin I converting enzyme inhibitor (SQ 14,225).
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Drug Administration Schedule; Female; Food; Humans; H | 1983 |
[Relation between hormonal and hemodynamics indices during emotional stress in healthy individuals and in hypertensive patients].
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Hemodynamics; Humans; Hydro | 1983 |
Aldosterone suppression with dopamine infusion in low-renin hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; B | 1983 |
10. Hypertension. A comparison of the effects of angiotensin II infusion and variations in salt intake on plasma aldosterone levels in normal subjects, patients with essential hypertension and patients with hyperaldosteronism.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Corticosterone; Desoxycorticosterone; Dexa | 1983 |
[Corticotropin studies in essential hypertension].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hypertension; Male; | 1983 |
Angiotensin converting enzyme inhibition reveals an important role for the renin system in the control of normal and high blood pressure in man.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captop | 1983 |
The role of corticosteroids in the regulation of myocardial Na, K-ATPase in normotensive and spontaneously hypertensive rats.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Aldosterone; Animals; Blood Pressure; Body Weight; Dexametha | 1984 |
[Use of angiotensin converting enzyme inhibitor captopril and peripheral vasodilator minoxidil in the treatment of patients with stable and malignant arterial hypertension].
Topics: Adolescent; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; | 1983 |
Importance of the adrenal cortex for development and maintenance of hypertension in spontaneously hypertensive rats.
Topics: Adrenal Cortex; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Animals; Be | 1984 |
Androgen modulation of adrenal angiotensin receptors.
Topics: Adrenal Cortex; Aldosterone; Androgens; Angiotensin II; Angiotensin III; Animals; Cattle; Cell Membr | 1984 |
Renin, aldosterone, and serum-converting enzyme activity during normal and hypertensive pregnancy.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy Compl | 1984 |
19-nor-deoxycorticosterone excretion in primary aldosteronism and low renin hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Desoxycorticosterone; Fe | 1983 |
Environmental and physiological characteristics in adolescents genetically predisposed to hypertension.
Topics: Adolescent; Aldosterone; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Kallikreins; Kidn | 1983 |
6 beta-Hydroxyandrostenedione: evidence for a new hypertensinogenic agent.
Topics: Aldosterone; Androstenedione; Angiotensinogen; Angiotensins; Animals; Corticosterone; Hypertension; | 1983 |
Effect of captopril on blood pressure and on the renin-angiotensin-aldosterone system in coarctation of the aorta.
Topics: Adolescent; Adult; Aldosterone; Aortic Coarctation; Blood Pressure; Captopril; Dose-Response Relatio | 1983 |
Urinary prostaglandin E2 and kallikrein excretion in glucocorticoid hypertension in rats.
Topics: Aldosterone; Animals; Blood Pressure; Captopril; Dexamethasone; Dinoprostone; Hypertension; Kallikre | 1983 |
[Effects of excessive salt-loading on blood pressure, plasma norepinephrine concentration, plasma renin activity, plasma aldosterone concentration and urinary aldosterone excretion in patients with essential hypertension and normotensive subjects].
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nor | 1983 |
Role of the aldosterone system in the salt-sensitivity of patients with benign essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hypertensio | 1983 |
Changes in renal function induced by endralazine, a new antihypertensive drug.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Female; Glomerular Filtration Rate; Heart Rate | 1983 |
[Low renin variant of hypertension: functional relations of the renin-aldosterone pressor system].
Topics: Aldosterone; Diuresis; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Ang | 1983 |
Renin and aldosterone concentrations in pregnant essential hypertensives - a prospective study.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Labetalol; Methyldopa; Potassium; Pregnancy; Pregn | 1983 |
Effects of intravenous endralazine in essential hypertension.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Epinephrine; Female; Humans; Hypertensi | 1983 |
Ketamine hypertension and the renin-angiotensin system.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Ketamine; Renin; R | 1983 |
Increased urinary kallikrein excretion in young borderline hypertensive patients.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Kallikreins; Male; Renal Circulation; Renin; Sodiu | 1983 |
[Studies on the pathogenesis of arterial hypertension in acromegaly. I. The renin-angiotensin-aldosterone system].
Topics: Acromegaly; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Growth Hormone; Humans; Hydr | 1983 |
Adrenal cortical carcinoma: an unusual cause of hyperaldosteronism.
Topics: Adrenal Cortex Neoplasms; Adult; Aldosterone; Carcinoma; Humans; Hyperaldosteronism; Hypertension; H | 1983 |
Effects of penbutolol and metoprolol on blood pressure, plasma catecholamines and renin activity in hypertensive patients.
Topics: Aldosterone; Blood Pressure; Catecholamines; Female; Humans; Hypertension; Male; Metoprolol; Penbuto | 1983 |
Sympathetic nerve and hormonal responses to a single dose of nifedipine in patients with essential hypertension and normal subjects: comparison among renin-subgroups.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Female; Hormones; Humans; Hypertension; Male; Middle Aged; | 1983 |
Single dose captopril as a diagnostic test for primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Captopril; Diagnosis, Differential; Fema | 1983 |
[The pressor and adrenal responses to angiotensin II in patients with normoreninemic essential hypertension--the influence of sodium intake and captopril].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Captopril; Diet, Sodium-Restricted; Female; Humans; Hyp | 1983 |
[A new diagnostic test for primary tumoral hyperaldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Captopril; Humans; Hyperaldost | 1983 |
[Relation existing between the kallikrein-kinin and renin-angiotensin-aldosterone systems].
Topics: Aldosterone; Humans; Hypertension; Kallikreins; Kinins; Liver Cirrhosis; Renin; Renin-Angiotensin Sy | 1983 |
Effect of captopril on the renin-angiotensin system in hypertensive children.
Topics: Adolescent; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Child; Humans; Hypertension; Prol | 1983 |
Defect in the sodium-modulated tissue responsiveness to angiotensin II in essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Humans; Hypertension; Kinet | 1983 |
Renin-angiotensin system in normotensive and hypertensive patients with progressive systemic sclerosis: hyporesponsiveness of renin during captopril test.
Topics: Adult; Aged; Aldosterone; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Proline; Renin | 1983 |
[Urinary kallikrein and other vasoactive substances in patients with primary aldosteronism and essential hypertension].
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Kallikreins; Male; Middle Aged | 1983 |
Plasma catecholamines and autonomic nervous system function in patients with early renal insufficiency and hypertension: effect of clonidine.
Topics: Adult; Aged; Aldosterone; Clonidine; Female; Hemodynamics; Humans; Hypertension; Kidney Diseases; Ma | 1984 |
Plasma renin activity, blood uric acid and plasma volume in pregnancy-induced hypertension.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Plasma Volume; Pregnancy; Pregnancy Complications, | 1983 |
Fatal, low renin hypertension associated with a disturbance of cortisol metabolism.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Humans; Hydrocortisone; Hydroxysteroid Dehydroge | 1983 |
Captopril enhances vascular and adrenal responsiveness to angiotensin II in essential hypertension.
Topics: Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Humans; | 1984 |
[Acute antihypertensive effect of captopril in hypertensive patients: with special reference to kallikrein-kinin system].
Topics: Adult; Aldosterone; Blood Pressure; Bradykinin; Captopril; Female; Humans; Hyperaldosteronism; Hyper | 1983 |
[Relation between dopamine secretion and saltsensitivity in essential hypertension].
Topics: Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Dopamine; Epinephrine; Hematocrit; Huma | 1983 |
Acute arterial fibrinoid deposition and ischaemic parenchymal damage of the kidney. Pathogenic factors in the development of malignant hypertension.
Topics: Aldosterone; Animals; Arteries; Blood Urea Nitrogen; Corticosterone; Hypertension; Hypertension, Mal | 1983 |
The relationship of aldosterone to mild essential hypertension.
Topics: Adult; Aging; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Renin; Renin- | 1983 |
Unilateral hypersecretion of aldosterone associated with adrenal hyperplasia as a cause of primary aldosteronism.
Topics: Adrenal Cortex; Adrenal Glands; Adrenalectomy; Aldosterone; Female; Furosemide; Humans; Hyperaldoste | 1983 |
A comparison of biological effects of three angiotensin II antagonists in sodium depleted hypertensive patients.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypert | 1983 |
Effects of diuretic therapy in low-, normal- and high-renin isolated systolic systemic hypertension.
Topics: Adult; Aged; Aldosterone; Diuretics; Humans; Hypertension; Middle Aged; Prognosis; Renin; Sodium | 1984 |
Effects of long-term prazosin therapy on lipoprotein metabolism in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Lipoproteins; Male; Middle A | 1984 |
Effect of metoprolol on 24-hour urinary excretion of adrenal steroids and kallikrein in patients with essential hypertension.
Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Adult; Aldosteron | 1984 |
Cation transport of red blood cells from hypertensive patients in Japan.
Topics: Adolescent; Adult; Aged; Aldosterone; Biological Transport; Erythrocytes; Female; Humans; Hypertensi | 1983 |
Elevation of plasma renin activity during pregnancy and rupture of a dissecting aortic aneurysm in a patient with primary aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Aortic Dissection; Aortic Rupture; Female; Hu | 1983 |
Urinary kallikrein activity (esterase activity), plasma renin activity, and urinary aldosterone excretion in kidney transplantation patients.
Topics: Adult; Aldosterone; Esterases; Female; Humans; Hypertension; Kallikreins; Kidney Transplantation; Ma | 1983 |
Effects of timolol on blood pressure, systemic hemodynamics, plasma renin activity, and glomerular filtration rate in patients with essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; | 1984 |
[The role of sodium and potassium in borderline hypertension].
Topics: Adult; Aldosterone; Blood Pressure; Cardiac Output; Heart Rate; Humans; Hypertension; Male; Potassiu | 1983 |
[Differential aspects of the dynamics of the renin-angiotensin-aldosterone system in obesity with and without hypertension and in essential arterial hypertension].
Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Female; Humans; Hypertension; Male; Middle Aged; Ob | 1983 |
[Treatment of arterial hypertension patients depending on renin activity].
Topics: Aldosterone; Antihypertensive Agents; Diuretics; Humans; Hypertension; Kallikreins; Prekallikrein; R | 1984 |
An exaggerated natriuretic response to hypertonic saline infusion in the stage II (who stage classification) essential hypertensive patients.
Topics: Adult; Aldosterone; Diuresis; Extracellular Space; Female; Humans; Hypertension; Male; Middle Aged; | 1984 |
[Plasma renin activity and plasma aldosterone change in diabetic nephropathy].
Topics: Adult; Aldosterone; Diabetic Nephropathies; Female; Humans; Hypertension; Male; Middle Aged; Posture | 1983 |
Urinary kallikrein excretion in patients with primary aldosteronism: differentiation of adrenal adenoma from idiopathic adrenal hyperplasia.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Diagnosis, Differential; Diet, | 1984 |
Thiazide-induced potassium loss not prevented by beta blockade.
Topics: Aldosterone; Amiloride; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrochlorothi | 1984 |
Effect of angiotensin III on blood pressure, renin-angiotensin-aldosterone system in normal and hypertensive subjects.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Angiotensin III; Blood Pressure; Female; Humans; Hyd | 1984 |
[Changes in the renin-angiotensin-aldosterone and kallikrein systems in normo- and hypertensive pregnant women].
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Kallikreins; Pregnancy; Pregnancy Complications, C | 1984 |
[Nyctohemeral values of plasma renin and aldosterone in relation to age, sex and sodium intake and posture].
Topics: Adolescent; Adult; Age Factors; Aged; Aldosterone; Circadian Rhythm; Diet; Female; Humans; Hypertens | 1983 |
A case of normotensive primary aldosteronism--comparison with 13 previously experienced cases with hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Female; Humans; Hyperaldosteronism; H | 1984 |
[Study on renin-angiotensin-aldosterone system. II. Changes of plasma renin activity, plasma aldosterone concentration and urinary sodium excretion in the hypertensives].
Topics: Adult; Aldosterone; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Aged; Renin; | 1984 |
[Features of vascular reactivity, sodium metabolism and its humoral regulation in healthy subjects with a family history of hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Middle Aged; Norepin | 1984 |
Primary aldosteronism due to adrenal carcinomas.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Combined Modality Therapy; Female; Foll | 1984 |
Acute effect of captopril on serum lipid peroxides level in hypertensive patients.
Topics: Adult; Aldosterone; Captopril; Female; Humans; Hypertension; Lipid Peroxides; Male; Proline; Renin-A | 1984 |
[Juvenile essential hypertension. II. Plasma renin activity and levels of aldosterone at rest and after loading in children with juvenile essential hypertension].
Topics: Adolescent; Aldosterone; Cold Temperature; Humans; Hypertension; Posture; Renin | 1984 |
[Dopaminergic modulation of salt sensitivity in essential hypertension].
Topics: Aldosterone; Catecholamines; Diet, Sodium-Restricted; Dopamine; Female; Humans; Hypertension; Male; | 1984 |
[Comparison of effects of two angiotensin II antagonists on blood pressure, heart rate, plasma renin activity, and plasma aldosterone concentration in the same hypertensive patients].
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Angiotensin II; Blood Pressure; Heart R | 1984 |
[Effects of guanabenz on plasma renin and aldosterone and on sodium balance in hypertensive patients].
Topics: Adult; Aldosterone; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Renin; S | 1984 |
[Effect of guanabenz alone and in association with a diuretic on blood pressure and on the renin-angiotensin-aldosterone system in hypertensive patients].
Topics: Adult; Aged; Aldosterone; Chlorthalidone; Drug Therapy, Combination; Guanabenz; Guanidines; Heart Ra | 1984 |
[Circadian rhythms of the renin-angiotensin-aldosterone system in hypertension patients].
Topics: Aldosterone; Circadian Rhythm; Furosemide; Humans; Hypertension; Renin; Renin-Angiotensin System; Ti | 1984 |
Acute effect of atenolol on hemodynamic, plasma renin activity and plasma aldosterone concentration in the once daily oral administration.
Topics: Administration, Oral; Adult; Aldosterone; Atenolol; Blood Pressure; Cardiac Output; Female; Heart Ra | 1984 |
Effect of indapamide on the renin-aldosterone system, and urinary excretion of potassium and calcium in essential hypertension.
Topics: Adult; Aldosterone; Calcium; Creatinine; Diuretics; Female; Humans; Hypertension; Indapamide; Male; | 1984 |
Clinical syndromes associated with disorders of renal tubular chloride transport: excess and deficiency of a circulating factor?
Topics: Aldosterone; Angiotensin II; Bartter Syndrome; Body Weight; Chlorides; Female; Furosemide; Humans; H | 1984 |
Circulatory volume in essential hypertension. Relationships with age, blood pressure, exchangeable sodium, renin, aldosterone and catecholamines.
Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Blood Pressure; Blood Volume; Body Height; Body Surface | 1984 |
Renin, angiotensin II, aldosterone, catecholamines, prostaglandins and vasopressin. The importance of pressor and depressor factors for hypertension in pregnancy.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Catecholamines; Female; Humans | 1984 |
Hemodynamic effects of a competitive renin inhibitory peptide in humans: evidence for multiple mechanisms of action.
Topics: Adult; Aldosterone; Angiotensinogen; Blood Pressure; Captopril; Drug Interactions; Heart Rate; Hemod | 1983 |
Characteristics of hypertension in primary IgA glomerulonephritis.
Topics: Adolescent; Adult; Aldosterone; Child; Female; Glomerulonephritis, IGA; Humans; Hypertension; Indome | 1984 |
[Radioimmunoassay in the diagnosis of arterial hypertension].
Topics: Adrenal Gland Neoplasms; Aldosterone; Catecholamines; Diagnosis, Differential; Humans; Hyperaldoster | 1984 |
Abnormal relation of extracellular fluid volume and exchangeable sodium with systemic arterial pressure in early borderline essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Extracellular Space; Female; Homeostasis; Humans; Hypertension; | 1984 |
Comparison of the effects of diuretic therapy and low sodium intake in isolated systolic hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Diuretics; Female; H | 1984 |
Therapeutic effect of exercise on hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Female; Heart Rate; Humans; Hypertension; Lactat | 1984 |
Comparison of long-term renal hemodynamic effects of methyldopa and propranolol in patients with hypertension and renal insufficiency.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Female; Furosemide; Humans; Hypertension; Kidney Diseases; | 1984 |
Effects of single dose administration of angiotension covering enzyme inhibitor (captopril) on blood pressure, plasma renin activity and plasma aldosterone in patients with essential hypertension. A proposal for the captopril test.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Female; Furosemide; Humans; Hypertension; Male; Middl | 1984 |
Effect of a moderately energy- and salt-reduced diet on body compartments and blood pressure control in obese men with mild hypertension.
Topics: Adipose Tissue; Aldosterone; Blood Pressure; Body Composition; Body Fluid Compartments; Diet, Reduci | 1984 |
Prediction of hyperkalemia associated with prolonged treatment with captopril by glucose-induced acute serum potassium changes.
Topics: Aldosterone; Blood Pressure; Captopril; Glucose; Glucose Tolerance Test; Humans; Hyperkalemia; Hyper | 1984 |
[Is there a relation between the renin-angiotensin-aldosterone system and vasopressin secretion in essential hypertension?].
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Diet, Sodium-Restricted; Female; Humans; H | 1984 |
[Recent findings on mineralocorticoids].
Topics: Aldosterone; Animals; Circadian Rhythm; Humans; Hyperaldosteronism; Hypertension; Kidney; Mineraloco | 1984 |
Intracellular concentration and transmembrane fluxes of sodium and potassium in erythrocytes of white normal male subjects with and without a family history of hypertension.
Topics: Aldosterone; Erythrocyte Membrane; Erythrocytes; Furosemide; Humans; Hypertension; Kallikreins; Male | 1984 |
Calf muscle haemodynamics and the renin-angiotensin-aldosterone system in normotensive subjects with a familial predisposition to hypertension: changes during increased salt intake.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Hemodynamics; Humans; Hypertension; | 1984 |
Enhanced response of plasma aldosterone to metoclopramide in essential hypertension.
Topics: Adult; Aldosterone; Humans; Hypertension; Male; Metoclopramide; Middle Aged; Posture; Potassium; Ren | 1984 |
Does potassium lower blood pressure by increasing sodium excretion? A metabolic study in patients with mild to moderate essential hypertension.
Topics: Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Potass | 1983 |
The natriuretic response to acute saline loading in normotensive and hypertensive renal transplant recipients.
Topics: Adult; Aldosterone; Blood Pressure; Creatinine; Female; Humans; Hypertension; Kidney Transplantation | 1983 |
Failure of angiotensin II to reduce plasma renin activity in hypertensive pregnant women.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Drug Evaluation; Female; Humans; Hypertension; M | 1984 |
[Effects of potassium on renin and aldosterone].
Topics: Aldosterone; Diuretics; Humans; Hypertension; Potassium; Renin | 1984 |
Direct and indirect measurement of urinary kallikrein excretion in patients with essential hypertension and normotensives: relation to age and plasma renin and aldosterone levels.
Topics: Adult; Age Factors; Aldosterone; Female; Humans; Hypertension; Kallikreins; Male; Middle Aged; Potas | 1984 |
'Essential' hypertension with hypokalemia. Caused by aldosterone-secreting adrenal adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Aged; Aldosterone; Chronic Disease; Humans; Hyperaldosteronism; Hy | 1984 |
Metabolic and mechanical properties of aortas from aldosterone-salt hypertensive rats.
Topics: Aldosterone; Animals; Aorta; Biological Transport; Biomechanical Phenomena; Energy Metabolism; Hyper | 1984 |
Irvine H. Page lecture 1982. A new look at the old mosaic.
Topics: Aldosterone; Animals; Hemodynamics; Homeostasis; Humans; Hypertension; Hypertension, Renal; Water-El | 1984 |
Oral potassium chloride and amiloride in hydrochlorothiazide-induced potassium loss.
Topics: Administration, Oral; Adult; Aldosterone; Amiloride; Biological Availability; Creatinine; Drug Evalu | 1984 |
[A simple radioimmunoassay determination of urinary aldosterone using 125I-labeled ligand [ALDOCTK-125KIT] and its clinical application].
Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Cushing Syndrome; Female; Glomerulonephritis; Huma | 1984 |
Adrenocortical function in the course of long-term verapamil treatment.
Topics: Adrenal Cortex; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; | 1984 |
Primary hyperaldosteronism during pregnancy.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi | 1984 |
Cardiovascular and adrenal sensitivity to angiotensin II in essential hypertension.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; | 1984 |
[Current aspects of diuretic use].
Topics: Aldosterone; Benzothiadiazines; Calcium; Carbonic Anhydrase Inhibitors; Diuretics; Diuretics, Osmoti | 1984 |
Flurbiprofen interaction with single doses of atenolol and propranolol.
Topics: Adult; Aldosterone; Atenolol; Blood Pressure; Body Weight; Female; Flurbiprofen; Heart Rate; Humans; | 1984 |
The adrenal cortex and hypertension.
Topics: Adrenal Cortex; Aldosterone; Cushing Syndrome; Diagnosis, Differential; Glucocorticoids; Humans; Hyp | 1983 |
[The effect of dopaminergic stimulation and inhibition on the urinary excretion of aldosterone and kallikrein in spontaneously hypertensive rats].
Topics: Aldosterone; Animals; Bromocriptine; Dopamine; Hypertension; Kallikreins; Male; Metoclopramide; Natr | 1983 |
[Relation between kallikreinuria and the renin-angiotensin-aldosterone system in patients with arterial hypertension].
Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Kallikreins; Male; Middle Aged; Re | 1984 |
[Effects of salt loading on urinary excretion of kallikrein in normotensive subjects and patients with essential hypertension].
Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Kallikreins; Male; Middle Aged; Refere | 1984 |
Relation of rates of excretion of urinary prostaglandin E metabolites to administration of angiotensin, aldosterone, and spironolactone in vivo.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Angiotensin II; Animals; Hypertension; Male; Prostagland | 1984 |
Pre-eclampsia: a hypothesis for its pathogenesis.
Topics: Aldosterone; Female; Glomerular Filtration Rate; Humans; Hypertension; Posture; Pre-Eclampsia; Pregn | 1984 |
[Water and electrolyte distribution and indices of central hemodynamics in patients with hypertension with different levels of urinary excretion of catecholamines and different plasma levels of aldosterone and cortisol].
Topics: Adolescent; Adult; Aged; Aldosterone; Catecholamines; Female; Hemodynamics; Humans; Hydrocortisone; | 1983 |
[Strategy for hormonal study in the arterial hypertension of acromegaly].
Topics: Acromegaly; Adenoma; Adrenal Gland Neoplasms; Aldosterone; Body Fluid Compartments; Diet, Sodium-Res | 1983 |
[Possible correlation between intralymphocytic sodium and plasma aldosterone].
Topics: Aldosterone; Humans; Hypertension; Liver Cirrhosis; Lymphocytes; Sodium | 1983 |
Corticosteroid modulation of the renin system and blood pressure in the spontaneously hypertensive rat.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Aldosterone; Angiotensinogen; Animals; Blood | 1983 |
Predictability of antihypertensive efficacy of selective beta 1 blockers.
Topics: Adult; Aldosterone; Atenolol; Blood Pressure; Cardiac Output; Catecholamines; Echocardiography; Fema | 1983 |
Potassium load in spontaneously hypertensive rats. Effects on blood pressure, renin-angiotensin, aldosterone, and intracellular electrolytes.
Topics: Aldosterone; Animals; Blood Pressure; Calcium; Electrolytes; Hypertension; Intracellular Fluid; Male | 1983 |
Effects of bromocriptine on the circadian rhythm of 18-hydroxycorticosterone and cortisol secretion in essential hypertensives.
Topics: 18-Hydroxycorticosterone; Adult; Aldosterone; Bromocriptine; Circadian Rhythm; Corticosterone; Human | 1983 |
Relation of blood pressure with body and plasma electrolytes in Conn's syndrome.
Topics: Adult; Aldosterone; Blood Pressure; Electrolytes; Female; Humans; Hyperaldosteronism; Hypertension; | 1983 |
The antihypertensive effect of dietary potassium chloride loading in rats with adrenal regeneration hypertension.
Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Blood Proteins; Corticosterone; Electrolytes; | 1984 |
Blood pressure and intra-erythrocyte sodium during normal and high salt intake in middle-aged men: relationship to family history of hypertension, and neurogenic and hormonal variables.
Topics: Aldosterone; Blood Pressure; Body Weight; Diet; Dopamine; Epinephrine; Erythrocytes; Heart Rate; Hum | 1984 |
The renin-angiotensin-aldosterone system and circadian rhythm of urine variables in normotensive and hypertensive subjects.
Topics: Aldosterone; Animals; Blood Pressure; Catecholamines; Chlorine; Circadian Rhythm; Creatinine; Humans | 1984 |
Primary aldosteronism. Clinical management.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Diagnosis, Di | 1984 |
Relationship between plasma aldosterone and angiotensin II before and after noradrenergic inhibition in normal subjects and patients with mild essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Debrisoquin; Female; Humans; Hypertension; | 1984 |
Adrenal adenoma with 18-hydroxycorticosterone excess and hypertension: a variant of aldosteronomas.
Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Aldosterone; Corticosterone; Female; Hum | 1984 |
Hypertension and age: clinical and biochemical correlates.
Topics: Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Blood Volume; Furosemide; Humans; Hypertensio | 1982 |
Enhanced renin levels after discontinuation of furosemide: additional effects of loop diuretics on renin release.
Topics: Adult; Aged; Aldosterone; Furosemide; Humans; Hypertension; Kidney Function Tests; Male; Middle Aged | 1982 |
Alcohol and hypertension.
Topics: Adult; Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Aldosterone; Blood Pressure; Dopam | 1982 |
Endocrine factors in juvenile essential hypertension.
Topics: Adult; Aldosterone; Corticosterone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hypertensi | 1982 |
The effect of high-sodium intake and furosemide on blood pressure and other related variables in salt-sensitive hypertension.
Topics: Aldosterone; Blood Pressure; Cardiac Output; Diet; Dinoprostone; Furosemide; Humans; Hypertension; N | 1982 |
Effect of ageing on circadian rhythms of plasma renin and aldosterone in mesor-hypertensive women.
Topics: Adolescent; Adult; Aging; Aldosterone; Circadian Rhythm; Female; Humans; Hypertension; Menstruation; | 1982 |
Hypertension in adult onset diabetes mellitus: abnormal renal hemodynamics and endogenous vasoregulatory factors.
Topics: Aldosterone; Blood Glucose; Blood Pressure; Blood Volume; Diabetes Complications; Diabetes Mellitus; | 1982 |
Hemodynamic and endocrine changes associated with captopril in diuretic-resistant hypertensive patients.
Topics: Adult; Aldosterone; Benzothiadiazines; Blood Pressure; Captopril; Cardiac Output; Diuretics; Female; | 1982 |
Identifying aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension; Renin | 1982 |
Circadian blood pressure and renin, aldosterone, cortisol, and prolactin levels in hypertensive pseudohypoparathyroid patients.
Topics: Adult; Aldosterone; Blood Pressure; Circadian Rhythm; Female; Hormones; Humans; Hydrocortisone; Hype | 1982 |
Rapid increase of mineralocorticoids after furosemide in low-renin essential hypertension: evidence for 18-hydroxycorticosterone to be a better marker than aldosterone.
Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adult; Aldosterone; Corticosterone; Female | 1982 |
The renin-aldosterone system in pre-eclampsia, essential and transient hypertension during pregnancy, and normotensive pregnant and non-pregnant control subjects.
Topics: Aldosterone; Blood Pressure; Creatinine; Female; Humans; Hypertension; Potassium; Pre-Eclampsia; Pre | 1982 |
Long-term captopril treatment in moderate to severe hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Captopril; Diuretics; Drug Therapy, Combination; Female; H | 1982 |
Prostaglandins, catecholamines, renin and aldosterone during hypertensive and normotensive pregnancy.
Topics: Aldosterone; Dinoprost; Dinoprostone; Epinephrine; Female; Humans; Hypertension; Norepinephrine; Pre | 1982 |
Aldosterone and its metabolism in spontaneously hypertensive rats (SHR).
Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Hypertension; Kinetics; Male; Potassium; Rats; | 1982 |
Simplified screening procedures for primary aldosteronism. Studies on the mechanism of the hyper-responsiveness to furosemide and standing.
Topics: Aldosterone; Blood Pressure; Furosemide; Humans; Hyperaldosteronism; Hypertension; Mass Screening; P | 1982 |
Recurrence of hypertension in primary aldosteronism after discontinuation of spironolactone. Time course of changes in cardiac output and body fluid volumes.
Topics: Aldosterone; Blood Pressure; Cardiac Output; Humans; Hyperaldosteronism; Hypertension; Potassium; Re | 1982 |
Renin subgroups in essential hypertension.
Topics: Aldosterone; Blood Pressure; Creatinine; Female; Heart Rate; Hematocrit; Humans; Hypertension; Kidne | 1982 |
Characterization of a group of essential hypertensives with impaired regulation of aldosterone.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; | 1982 |
The salivary sodium/potassium ratio in hypertension: relation to race and plasma renin activity.
Topics: Adult; Aldosterone; Black People; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Middle A | 1982 |
The role of aldosterone in the response to treatment of primary hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Chlorthalidone; Female; Humans; Hypertension; Male; Middle | 1982 |
Glucose-induced hyperkalemia developing in the upright position in captopril-treated hypertensives.
Topics: Adolescent; Adult; Aged; Aldosterone; Captopril; Diabetes Mellitus; Female; Glucose; Glucose Toleran | 1982 |
Sodium and potassium status, plasma renin and aldosterone profiles in normotensive and hypertensive Johannesburg blacks.
Topics: Adult; Aldosterone; Black or African American; Blood Pressure; Creatinine; Female; Humans; Hypertens | 1982 |
Plasma volume, electrolyte, and endocrine changes during onset of laminitis hypertension in horses.
Topics: Acute Disease; Aldosterone; Animals; Electrolytes; Female; Horse Diseases; Horses; Hydrocortisone; H | 1982 |
Renal function in borderline hypertensive first-degree relatives of essential hypertensives. Effects of sodium load.
Topics: Adolescent; Adult; Aldosterone; Electrolytes; Female; Humans; Hypertension; Kidney; Kidney Function | 1982 |
Humoral mechanisms of arterial hypertension in patients in the acute phase of myocardial infarction.
Topics: Adult; Aged; Aldosterone; Catecholamines; Female; Hemodynamics; Humans; Hydrocortisone; Hypertension | 1982 |
Increased adrenergic activity during pregnancy-induced hypertension.
Topics: Adult; Aldosterone; Epinephrine; Female; Humans; Hypertension; Norepinephrine; Pregnancy; Pregnancy | 1982 |
The renin-angiotensin-aldosterone system and blood pressure during oxprenolol treatment in hypertensive patients pretreated with diuretics.
Topics: Adult; Aldosterone; Amiloride; Blood Pressure; Body Weight; Diuretics; Drug Combinations; Female; Hu | 1982 |
[Effect of prazosin on catecholamines, renin-aldosterone system and prostaglandins in primary hypertension].
Topics: Adult; Aldosterone; Catecholamines; Female; Humans; Hypertension; Male; Middle Aged; Prazosin; Prost | 1982 |
[Circadian rhythms of renin, aldosterone and cortisol in essential arterial hypertension with recent, confirmed and complicated appearance].
Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Female; Humans; Hydrocortisone; Hypertension; Male | 1981 |
[Evaluation and correlation of various hemodynamic and humoral parameters in stable essential hypertension].
Topics: Adult; Aldosterone; Blood Volume; Cardiovascular System; Humans; Hypertension; Middle Aged; Renin | 1981 |
Enhanced vascular reactivity to norepinephrine in salt-sensitive patients with hypertension.
Topics: Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Midd | 1982 |
[Urinary excretion of aldosterone in patients with hypertension].
Topics: Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Plasma Volume; Potassium; | 1982 |
Renin angiotensin aldosterone system and adrenergic system in normotensive and hypertensive pregnancy.
Topics: Adult; Aldosterone; Epinephrine; Female; Humans; Hypertension; Norepinephrine; Pregnancy; Pregnancy | 1982 |
The sympathetic nervous system in primary hypertension.
Topics: Adult; Age Factors; Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Nore | 1982 |
Effects of various doses of captopril on plasma aldosterone concentrations in patients with essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Female; Humans; Hyp | 1982 |
[Catecholamines in the blood and the renin-angiotensin-aldosterone axis in essential hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Catecholamines; Electrolytes; Female; Humans; Hypertension; Male | 1981 |
[Adrenergic factors in the hemodynamic adaptation to effort].
Topics: Adaptation, Physiological; Aldosterone; Catecholamines; Hemodynamics; Humans; Hypertension; Labetalo | 1981 |
Leucocyte cation transport in essential hypertension: its relation to the renin-angiotensin system.
Topics: Aldosterone; Angiotensin II; Biological Transport; Diet, Sodium-Restricted; Humans; Hypertension; Le | 1981 |
Relation between arterial pressure, dietary sodium intake, and renin system in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Diet; Diet, Sodium-Restricted; Female; Humans; Hypertension; Mal | 1981 |
Investigation of the mechanism of action of prostaglandin synthesis inhibitors on renin and aldosterone secretion and sodium excretion.
Topics: Adult; Aldosterone; Cyclooxygenase Inhibitors; Humans; Hypertension; Indomethacin; Male; Middle Aged | 1981 |
Catecholamines, renin, aldosterone, and blood volume during chronic minoxidil therapy.
Topics: Aldosterone; Blood Volume; Epinephrine; Female; Humans; Hypertension; Long-Term Care; Male; Middle A | 1981 |
The effect of captopril on catecholamines, renin activity, angiotensin II and aldosterone in plasma during physical exercise in hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Catecholamines; Female; Humans; Hyper | 1981 |
Responsiveness of the renin-aldosterone system during exercise in young patients with essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Blood Proteins; Female; Heart Rate; Humans; Hypertension; Male; | 1981 |
Reduction of plasma and urinary vasopressin during treatment of severe hypertension by captopril.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middl | 1981 |
Long-term efficacy of captopril in renovascular and essential hypertension.
Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Female | 1982 |
Captopril in the long-term treatment of essential hypertension: changes in the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Dose-Response Relationship, D | 1982 |
Long-term treatment of childhood hypertension with captopril.
Topics: Adolescent; Adult; Aldosterone; Captopril; Child; Electrocardiography; Female; Humans; Hypertension; | 1982 |
[The renin-angiotensin system and the sympathetic nervous system in essential hypertension].
Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Epinephrine; Female; Humans; Hypertension; Male; Mi | 1982 |
[The renin-angiotensin-aldosterone system and the adrenergic system in normal pregnancy and hypertension induced by pregnancy].
Topics: Aldosterone; Epinephrine; Female; Humans; Hypertension; Norepinephrine; Pregnancy; Pregnancy Complic | 1982 |
Effects on the renin-angiotensin system of agents acting at central and peripheral adrenergic receptors.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clonidine; Double-Blind Method; Female; Humans; Hypertensi | 1983 |
Achievements in hypertension: a 25 year overview.
Topics: Aldosterone; Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Obesity; Renin-Angiotensin | 1983 |
Aldosterone 21-sulphate in man.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Animals; Biological A | 1983 |
Hypersensitivity of spontaneously hypertensive rats to heat and ether before the onset of high blood pressure.
Topics: Adrenal Glands; Aldosterone; Animals; Ascorbic Acid; Blood Pressure; Cholesterol; Corticosterone; Et | 1983 |
[Changes in water-sodium balance in patients with hypertension subjected to different types of hypotensive therapy].
Topics: Adult; Aged; Aldosterone; Angiotensin I; Chlorthalidone; Extracellular Space; Female; Hemodynamics; | 1983 |
[Total plasma aldosterone content in hypertension].
Topics: Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Plasma Volume | 1983 |
Renal denervation and sodium balance in young spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Denervation; Hypertension; Kidney; Male; Rats; Rats, Mutant Strains; Sodium | 1983 |
Aldosterone metabolites and possible aldosterone precursors in hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Antigen-Antibody Comple | 1983 |
[Current neurohumoral and therapeutic aspects of hypertension].
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Female; Humans; Hypertension; Kallikreins; Male; | 1981 |
Primary hyperaldosteronism in pregnancy.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Female; Humans; Hyperaldosteron | 1982 |
Tobacco chewer's hypokalemia: licorice revisited.
Topics: Aged; Aldosterone; Alkalosis; Glycyrrhiza; Humans; Hypertension; Hypokalemia; Male; Nicotiana; Plant | 1980 |
Fludrocortisone suppression test in normal subjects, in patients with essential hypertension and in patients with various forms of aldosteronism.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosteron | 1980 |
Acute effects of saralasin on plasma aldosterone in different pathophysiological conditions.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Bartter Syndrome; Child; Diet, Sodium-Restricted; Fe | 1980 |
[Hemodynamics and the renin-angiotensin-aldosterone system in primary hypertension].
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Hemodynamics; Humans; Hypertension; Male; Middle Age | 1980 |
Hypertension in a four-year-old child: gas chromatographic and mass spectrometric evidence for deficient hepatic metabolism of steroids.
Topics: Aldosterone; Alkalosis; Child, Preschool; Gas Chromatography-Mass Spectrometry; Humans; Hypertension | 1980 |
[Plasma renin, aldosterone, and dopamine-beta-hydroxylase activity in hypertensive patients over 70 years of age (author's transl)].
Topics: Aged; Aldosterone; Dopamine beta-Hydroxylase; Female; Humans; Hypertension; Male; Posture; Renin | 1980 |
Prostaglandins and plasma renin activity in hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Electrolytes; Glomerular Filtration Rate; Humans; Hypertension; | 1980 |
The effect of clonidine on renin and aldosterone of hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Hydrocortisone; Hypertens | 1980 |
Integrated concentration of epinephrine and norepinephrine in normal subjects and in patients with mild essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Child; Epinephrine; Humans; Hydrocortisone; Hyperten | 1980 |
Saralasin infusion in renovascular and essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Heart Rate; Humans; Hyperten | 1980 |
[Pathogenesis of arterial hypertension].
Topics: Adolescent; Adult; Age Factors; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; M | 1980 |
Radioreceptor assay of plasma mineralocorticoid activity. Role of aldosterone, cortisol, and deoxycorticosterone in various mineralocorticoid-excess states.
Topics: Adolescent; Aldosterone; Binding, Competitive; Child, Preschool; Desoxycorticosterone; Humans; Hydro | 1980 |
Body fluid volumes and the response of renin and aldosterone to short- and long-term thiazide therapy of essential hypertension.
Topics: Adult; Aldosterone; Extracellular Space; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male | 1980 |
Neurogenic factors in low renin essential hypertension.
Topics: Adolescent; Adult; Age Factors; Aldosterone; Blood Pressure; Epinephrine; Female; Furosemide; Humans | 1980 |
Evidence for a subgroup of essential hypertensives with non-suppressible excretion of aldosterone during sodium loading.
Topics: Aldosterone; Humans; Hypertension; Potassium; Renin; Sodium; Spironolactone | 1980 |
Renin-hyporesponsiveness in essential hypertension. Dissociation between plasma renin and catecholamines or aldosterone following furosemide.
Topics: Adult; Aged; Aldosterone; Catecholamines; Female; Furosemide; Humans; Hypertension; Male; Middle Age | 1980 |
Hypertension in the elderly.
Topics: Adult; Aged; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Vessels; Blood Volum | 1980 |
Etiological considerations in Gordon's syndrome: possible role of prostaglandins.
Topics: Acidosis; Aldosterone; Bradykinin; Humans; Hyperkalemia; Hypertension; Kidney; Prostaglandins; Prost | 1980 |
Renin-angiotensin-aldosterone system in arterial hypertension.
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Fa | 1980 |
The state of certain humoral systems and haemodynamics in healthy subjects and in patients with essential hypertension with excessive salt intake.
Topics: Aldosterone; Blood Volume; Diuresis; Furosemide; Hemodynamics; Humans; Hydrocortisone; Hypertension; | 1980 |
Abnormal adrenal and vascular responses to angiotensin II and an angiotensin antagonist in acromegaly.
Topics: Acromegaly; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restric | 1980 |
The renin-aldosterone system in secondary hypertension: relationship to blood pressure and plasma electrolytes.
Topics: Aldosterone; Blood Pressure; Electrolytes; Humans; Hyperaldosteronism; Hypertension; Kidney Failure, | 1980 |
A comparative study on (des-aspartyl1)-angiotensin II and angiotensin II in patients with essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin III; Blood Pressure; Humans; Hypertension; Middle Ag | 1980 |
Effect of propranolol on the urinary excretion of prostaglandin E and plasma renin activity in hypertensive patients.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; | 1980 |
Long-term effects of captopril in hypertension.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Captopril; Child; Electrolytes; Humans; Hypertension | 1980 |
The renin-aldosterone system in low-dose chlorothiazide treatment of hypertensive subjects.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Chlorothiazide; Humans; Hypertension; Middle Aged; R | 1980 |
[Blood volume, plasma renin activity and plasma aldosterone concentration in patients with essential hypertension who were treated for more than ten years (author's transl)].
Topics: Adult; Aged; Aldosterone; Blood Volume; Diuretics; Female; Humans; Hypertension; Male; Middle Aged; | 1980 |
A simplified screening test for differentiating primary aldosteronism from essential hypertension with low plasma renin activity.
Topics: Aldosterone; Dexamethasone; Diagnosis, Differential; Furosemide; Humans; Hyperaldosteronism; Hyperte | 1980 |
Dopaminergic Modulation of renin activity and aldosterone and prolactin secretion in the spontaneously hypertensive rat.
Topics: Aldosterone; Animals; Blood Pressure; Dopamine Antagonists; Hypertension; Levodopa; Male; Metoclopra | 1980 |
[Renin-angiotensin-aldosterone system in diabetes, arterial hypertension and orthostatic hypotension].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Diabetes Mellitus; Female; Humans; Hyperte | 1980 |
Factors influencing blood pressure in salt-sensitive patients with hypertension.
Topics: Aldosterone; Autonomic Nervous System; Cardiac Output; Diet, Sodium-Restricted; Female; Furosemide; | 1980 |
Different patterns in essential hypertension and possible choice of antihypertensive drugs.
Topics: Adult; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Cardiac Output; Catecholamines; | 1980 |
[Renin-angiotensin system. Physiological importance. Methods and study in humans (author's transl)].
Topics: Adolescent; Adrenal Gland Diseases; Adult; Aldosterone; Angiotensins; Blood Pressure; Child; Child, | 1980 |
Captopril in clinical hypertension. Changes in components of renin-angiotensin system and in body composition in relation to fall in blood pressure with a note on measurement of angiotensin II during converting enzyme inhibition.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Captopril; Diuretics; Humans; Hypertension; Potassium; | 1980 |
Relationships between sodium clearance, plasma renin activity, plasma aldosterone, renal hemodynamics and blood pressure in essential hypertension.
Topics: Aldosterone; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Malignant; Kidney; p-Am | 1980 |
The kallikrein-kinin system in essential hypertension.
Topics: Adult; Aldosterone; Animals; Bartter Syndrome; Blood Pressure; Bradykinin; Guinea Pigs; Humans; Hype | 1980 |
Urinary kallikrein in normotensive subjects and in patients with essential hypertension.
Topics: Adult; Aldosterone; Animals; Creatinine; Dogs; Female; Furosemide; Humans; Hypertension; Kallikreins | 1980 |
Dissociated renin-aldosterone response to acute sodium depletion in patients with a previous history of pregnancy-associated hypertension.
Topics: Adolescent; Adult; Aldosterone; Bendroflumethiazide; Blood Pressure; Body Weight; Female; Humans; Hy | 1980 |
[Evaluation of the differences in responsiveness of plasma renin activity to five different stimulations in essential hypertension (author's transl)].
Topics: Adult; Aged; Aldosterone; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypertension; Male; M | 1980 |
Captopril in diuretic-treated hypertensive patients.
Topics: Aged; Aldosterone; Captopril; Diuretics; Dizziness; Dose-Response Relationship, Drug; Drug Therapy, | 1980 |
Hyperkalemia resulting from captopril administration.
Topics: Aldosterone; Captopril; Humans; Hyperkalemia; Hypertension; Hyponatremia; Male; Middle Aged; Mineral | 1980 |
Renal function, plasma renin, and spontaneous diuresis in an advanced stage of hypertension in rats.
Topics: Aldosterone; Animals; Blood Pressure; Diuresis; Electrolytes; Hypertension; Kidney; Male; Rats; Reni | 1980 |
Plasma catecholamines, renin and aldosterone during combined alpha- and beta- adrenoceptor blockade in patients with severe arterial hypertension.
Topics: Adult; Aged; Aldosterone; Body Weight; Epinephrine; Ethanolamines; Female; Humans; Hypertension; Lab | 1980 |
The effect of dietary sodium in infancy on blood pressure and related factors. Studies of infants fed salted and unsalted diets for five months at eight months and eight years of age.
Topics: Aldosterone; Blood Pressure; Child; Diet, Sodium-Restricted; Extracellular Space; Growth; Humans; Hy | 1980 |
[Saralasin in subjects with low renin arterial hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Furosemide; Humans; Hypertension; Male; | 1980 |
Role of haemodynamics, catecholamines and renin in acute hypercalcaemic hypertension in man.
Topics: Adult; Aged; Aldosterone; Blood Volume; Calcium; Epinephrine; Hematocrit; Hemodynamics; Humans; Hype | 1980 |
Angiotensin II and not sodium status is the major determinant of the agonistic/antagonistic balance of saralasin's actions.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; M | 1980 |
Changes in endocrine activities relative to obesity in patients with essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Energy Intake; Female; Humans; Hy | 1981 |
[Essential hypertension with low levels of plasma renin activity: effects of propranolol on aldosteronemia, plasma volume and electrolyte balance].
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Plasma Volume; Propranolol; Ren | 1980 |
Suppression of captopril-induced increase in plasma renin activity by des-Asp1-,Ileu8-angiotensin II in man.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Blood Pressure; Captopril; Femal | 1981 |
Role of sympathetic nerve inhibition and body sodium-volume state in the antihypertensive action of clonidine in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Clonidine; Epinephrine; Female; Heart Rate; Humans; Hypertension | 1980 |
[Diagnostic significance of the determination of parameters of the renin-angiotensin-aldosterone system].
Topics: Adrenal Gland Diseases; Aldosterone; Angiotensins; Humans; Hypertension; Hypokalemia; Kidney Disease | 1980 |
Alteration of the volume-renin component in borderline essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Blood Volume; Diet, Sodium-Restricted; Female; Human | 1981 |
[Urinary prostaglandin E in patients with hypertension--relationship to renin-angiotensin-aldosterone system (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hyperaldosteronism; Hypertension; Male; Prostagl | 1980 |
Low-renin hypertension with hyperaldosteronism in childhood.
Topics: Aldosterone; Child; Dexamethasone; Glucocorticoids; Humans; Hyperaldosteronism; Hypertension; Remiss | 1980 |
[Renin-angiotensin-aldosterone system in essential hypertension. Inappropriately high plasma aldosterone in young patients with severe hypertension and in older hypertensives].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aldosterone; Angiotensin II; Female; Humans; Hyperten | 1980 |
Changes in urinary electrolytes versus serum electrolytes during treatment of primary hypertension with chlorthalidone alone and in combination with spironolactone.
Topics: Adult; Aldosterone; Chlorthalidone; Drug Therapy, Combination; Electrolytes; Humans; Hypertension; M | 1981 |
Interaction of minoxidil and captopril in the treatment of refractory hypertension.
Topics: Acidosis; Adolescent; Aldosterone; Captopril; Creatinine; Drug Interactions; Female; Humans; Hyperka | 1981 |
[Pseudo-Conn's syndrome after habitual ingestion of liquorice. Report on various clinical cases].
Topics: Adult; Aldosterone; Female; Glycyrrhiza; Humans; Hyperaldosteronism; Hypertension; Middle Aged; Plan | 1981 |
[Physiopathological aspects of arterial hypertension in obese subjects].
Topics: Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Obesity; Plasma Volume; R | 1980 |
[The dopaminergic system and aldosterone secretion. I. Suppressive effects of L-dopa on secondary hyperaldosteronism].
Topics: Adult; Aldosterone; Female; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Levodopa; Male | 1980 |
[The dopaminergic system and aldosterone secretion. II. Effect of L-dopa and dexamethasone on aldosterone biosynthesis].
Topics: Adult; Aldosterone; Dexamethasone; Female; Humans; Hydrocortisone; Hypertension; Levodopa; Male; Mid | 1980 |
Effects of captopril on blood pressure, electrolytes, and certain hormones in hypertension.
Topics: Aldosterone; Blood Pressure; Captopril; Electrolytes; Humans; Hypertension; Posture; Proline; Renin; | 1981 |
[Use of a radioimmunological study sequence for elucidating the role of vasopressor factors in the pathogenesis of hypertension].
Topics: Adult; Aldosterone; Chronic Disease; Coronary Disease; Humans; Hydrocortisone; Hypertension; Male; M | 1981 |
Prolonged clonidine treatment: catecholamines, renin activity and aldosterone following exercise in hypertensives.
Topics: Adult; Aldosterone; Clonidine; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male; Middle A | 1981 |
[Clinical observation of 12 cases of primary aldosteronism, special reference to the diagnostic problem (author's transl)].
Topics: Adrenal Cortex; Adult; Age Factors; Aged; Aldosterone; Circadian Rhythm; Female; Humans; Hyperaldost | 1980 |
Conn's syndrome in a patient with acromegaly.
Topics: Acromegaly; Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin II; Female; Humans; Hyperten | 1981 |
Plasma aldosterone response to angiotensin II in sodium-restricted elderly subjects with essential hypertension.
Topics: Aged; Aging; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; H | 1981 |
[Effects of angiotensin I converting enzyme inhibitor (captopril) on blood pressure, pulse rate, plasma renin activity, and plasma aldosterone concentration in patients with essential hypertension and normal subjects].
Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; | 1980 |
Alternate day steroids and blood pressure control after renal transplantation.
Topics: Aldosterone; Blood Pressure; Drug Administration Schedule; Humans; Hypertension; Immunosuppression T | 1980 |
Prevalence of primary aldosteronism.
Topics: Adult; Aged; Aldosterone; Denmark; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Ag | 1981 |
Captopril in primary hypertension. Effects related to the renin-angiotensin-aldosterone and kallikrein-kinin systems.
Topics: Adult; Aldosterone; Angiotensin II; Captopril; Female; Humans; Hypertension; Kallikreins; Kinins; Ma | 1981 |
A pathophysiologic study of the hypertension associated with burn injury in children.
Topics: Acute Disease; Aldosterone; Burns; Catecholamines; Child; Electrolytes; Fluid Therapy; Hemodynamics; | 1981 |
Angiotensin II and sodium as determinants of the agonistic--antagonistic balance of saralasin's actions.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Diet, Sodium-Restricted; Female; Huma | 1981 |
[Effects on long-term treatment with indapamide in subjects with essential arterial hypertension].
Topics: Adult; Aged; Aldosterone; Diuretics; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; Re | 1981 |
Effects of angiotensin II analog on blood pressure, renin and aldosterone in women on oral contraceptives and toxemia.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Angiotensin II; Blood Pressure; Contrac | 1981 |
[Renin activity and plasma aldosterone content in hypertension].
Topics: Adult; Aldosterone; Enzyme Activation; Humans; Hypertension; Middle Aged; Posture; Renin | 1981 |
Erythrocyte and total body potassium in untreated primary hypertension.
Topics: Adult; Aldosterone; Body Water; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Potas | 1981 |
Home blood pressure and circadian variation of blood pressure in the evaluation of hypertensive patients.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Blood Pressure; Blood Pressure Determination; Cap | 1981 |
Salt intake and hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Diet, Sodium-Restrict | 1981 |
Renal kallikrein-kinin: its relation to renal prostaglandins and renin-angiotensin-aldosterone in man.
Topics: Adult; Aldosterone; Circadian Rhythm; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypertens | 1981 |
Hypertension following renal transplantation: the role of the host's kidney.
Topics: Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Kidney; Kidney Transplantation; Middle Age | 1980 |
[Changes in the renin-angiotensin-aldosterone system during graduated ergometric tests in patients with essential arterial hypertension and in normal controls].
Topics: Adrenergic Fibers; Adult; Aldosterone; Angiotensin II; Exercise Test; Female; Humans; Hypertension; | 1981 |
Relationships between blood pressure and plasma renin, aldosterone and dopamine-beta--hydroxylase in the elderly. Studies in patients over 70 years of age.
Topics: Aged; Aldosterone; Blood Pressure; Dopamine beta-Hydroxylase; Female; Humans; Hypertension; Male; Re | 1981 |
[Effect of salt on the functional state of the renin-angiotensin-aldosterone system in healthy persons and hypertensives].
Topics: Adolescent; Adult; Aldosterone; Diuresis; Humans; Hydrocortisone; Hypertension; Middle Aged; Natriur | 1981 |
[Captopril in the treatment of hypertension (author's transl)].
Topics: Aldosterone; Angiotensin II; Captopril; Humans; Hypertension; Proline; Renin | 1981 |
Is renin a risk factor?
Topics: Aldosterone; Animals; Aortic Diseases; Arteriosclerosis; Cholesterol, Dietary; Diet, Atherogenic; Hy | 1981 |
Mineralocorticoid and metabolic response to metyrapone on normotensive children and children with dexamethasone-suppressible and primary hyperaldosteronism.
Topics: Aldosterone; Child; Desoxycorticosterone; Electrolytes; Female; Humans; Hyperaldosteronism; Hyperten | 1981 |
Captopril withdrawal after chronic therapy.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Epinephrine; Female; Humans; Hyperten | 1981 |
Acute effects of a new vasodilator, Ro 12-4713, on blood pressure, plasma Renin activity, Aldosterone and Catecholamine levels, and renal function in hypertensive and normal subjects.
Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Dose-Response Relationship, Drug; Female; Humans | 1981 |
Effect of chronic diuretic treatment on the plasma renin-angiotensin-aldosterone system in essential hypertension.
Topics: Adult; Aldosterone; Angiotensins; Diuretics; Electrolytes; Female; Humans; Hydrochlorothiazide; Hype | 1981 |
Primary aldosteronism -- screening, diagnosis and therapy.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Female; Humans; Hyperaldosteron | 1981 |
Relationship between blood pressure and blood levels of angiotensin I converting enzyme inhibitor (SQ 14,225).
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Chlorides; Endopeptidases; Female; Humans; Hypertensi | 1981 |
Correction of hypertension by partial nephrectomy in segmental renal artery stenosis and electron microscopic studies of renin.
Topics: Adolescent; Aldosterone; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Kidn | 1981 |
Acute hypercalcemic hypertension in man: role of hemodynamics, catecholamines, and renin.
Topics: Adult; Aged; Aldosterone; Blood Volume; Dopamine; Epinephrine; Hemodynamics; Humans; Hypercalcemia; | 1981 |
Elevated 'free' 18-hydroxy-corticosterone excretion as a possible indicator for early diagnosis of primary aldosteronism.
Topics: 18-Hydroxycorticosterone; Adult; Aldosterone; Corticosterone; Female; Humans; Hyperaldosteronism; Hy | 1981 |
A screening test to identify aldosterone-producing adenoma by measuring plasma renin activity. Results in hypertensive patients.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Midd | 1981 |
Screening for surgically correctable hypertension caused by primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 1981 |
[The relationship between lymphocyte sodium content and the renin-angiotensin-aldosterone system in subjects with essential arterial hypertension].
Topics: Adult; Aldosterone; Humans; Hypertension; Lymphocytes; Middle Aged; Renin; Renin-Angiotensin System; | 1981 |
Blood pressure and the renin--angiotensin--aldosterone system.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Middle Aged; Renin; Renin-A | 1981 |
Effect of angiotensin II and converting enzyme inhibitor (captopril) on blood pressure, plasma renin activity and aldosterone in primary aldosteronism.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Captopril; Humans; Hyperaldosteronism; Hypertension; Pr | 1981 |
Comparison of the effects of captopril, diuretic and their combination in low- and normal-renin essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Drug Evaluation; Drug Therapy, Combination; Humans; H | 1982 |
The effect of biofeedback-assisted relaxation training on blood pressure and selected biochemical parameters in patients with essential hypertension.
Topics: Adrenal Cortex; Adult; Aldosterone; Biofeedback, Psychology; Blood Pressure; Female; Humans; Hydroco | 1981 |
Body-fluid composition in normal and hypertensive man.
Topics: Adult; Aged; Aldosterone; Body Fluids; Body Water; Erythrocyte Volume; Extracellular Space; Humans; | 1982 |
[A case of glucocorticoid responsive aldosteronism (author's transl)].
Topics: Aldosterone; Dexamethasone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertensio | 1981 |
Rise in plasma concentration of aldosterone during long-term angiotensin II suppression.
Topics: Adult; Aldosterone; Angiotensin II; Captopril; Depression, Chemical; Female; Humans; Hypertension; M | 1981 |
Inter-relationship of sympathetic nervous system and renin-angiotensin-aldosterone system in three renin subgroups of borderline and persistent essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Dopamine beta-Hydroxylase; Female; Furo | 1981 |
Reversal of glucose-induced hyperkalemia by sodium restriction in "normaldosteronemic" diabetes mellitus.
Topics: Adult; Aged; Aldosterone; Blood Glucose; Diabetes Complications; Diet, Sodium-Restricted; Female; Gl | 1981 |
Circadian changes in plasma renin activity and plasma aldosterone concentration in one-kidney hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Circadian Rhythm; Constriction; Hypertension; Kidney; Male; Ra | 1982 |
Simple screening procedure for the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hype | 1981 |
Antihypertensive effect of the oral angiotensin I-converting enzyme inhibitor in long-term treatment of hypertensive patients.
Topics: Adult; Aged; Aldosterone; Bradykinin; Captopril; Female; Humans; Hypertension; Hypertension, Maligna | 1981 |
Renin, the heart and hypertension.
Topics: Aldosterone; Captopril; Heart Failure; Humans; Hypertension; Renin | 1982 |
Comparison of the hormonal and renal effects of captopril in severe essential and renovascular hypertension.
Topics: Aldosterone; Blood Pressure; Blood Volume; Captopril; Humans; Hypertension; Hypertension, Renal; Hyp | 1982 |
Changes of the intralymphocytic sodium concentration after acute and chronic captopril administration.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Humans; Hypertension; Lymphocytes; Middle Aged; Potas | 1982 |
Role of sympathetic nervous system activity in the blood pressure response to long-term captopril therapy in severely hypertensive patients.
Topics: Aldosterone; Blood Pressure; Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hype | 1982 |
Increase in plasma aldosterone during prolonged captopril treatment.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Humans; Hypertension; Hypertension, Renal; Hypertensi | 1982 |
Comparison of antihypertensive and hormonal effects of captopril and propranolol at rest and during exercise.
Topics: Aldosterone; Blood Pressure; Captopril; Drug Therapy, Combination; Humans; Hypertension; Male; Physi | 1982 |
Renin as a risk factor for atherogenesis. Part 3. Effects of hypercholesterolemia, hyporeninemia and one-kidney-one clip hypertension in the rabbit.
Topics: Aldosterone; Animals; Arteriosclerosis; Blood Pressure; Blood Urea Nitrogen; Body Weight; Cholestero | 1982 |
[Dopamine-beta-hydroxylase activity, aldosterone level, and plasma renin activity in patients with essential hypertension during exposure to physical load (author's transl)].
Topics: Adolescent; Adult; Aldosterone; Dopamine beta-Hydroxylase; Humans; Hypertension; Male; Physical Exer | 1982 |
Aldosterone in sustained essential hypertension.
Topics: Adult; Aldosterone; Extracellular Space; Humans; Hypertension; Inulin; Liver Circulation; Male; Midd | 1982 |
A vasodilator that avoids renin stimulation and fluid retention: antihypertensive treatment with trimazosin.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Body Fluids; Female; Heart Rate; | 1982 |
Effect of angiotensin converting enzyme inhibitor on serum aldosterone and potassium level.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Captopril; Diet, Sodium-Restricted; Female; Humans; Hypert | 1982 |
[The renin-aldosterone profile in hypertension].
Topics: Adult; Aldosterone; Circadian Rhythm; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin- | 1982 |
[Blood pressure, renin angiotensin aldosterone system and other cardiovascular risk factors in children of essential hypertensives (author's transl)].
Topics: Adolescent; Adult; Aldosterone; Blood Glucose; Blood Pressure; Child; Child, Preschool; Cholesterol; | 1982 |
19-hydroxyandrostenedione as a new hypertensinogenic agent.
Topics: Aldosterone; Androstenedione; Animals; Blood Pressure; Corticosterone; Desoxycorticosterone; Hyperte | 1982 |
The renin-angiotensin-aldosterone system and hypertension in primary hyperparathyroidism.
Topics: Adult; Aged; Aldosterone; Female; Furosemide; Humans; Hyperparathyroidism; Hypertension; Male; Middl | 1982 |
Effect of dietary sodium intake on the metabolism of prostaglandins in the kidney in hypertensive patients.
Topics: Adult; Aldosterone; Diet; Female; Humans; Hypertension; Male; Middle Aged; Prostaglandins; Renin; So | 1982 |
Sodium sensitivity and resistance in normotensive humans.
Topics: Adult; Age Factors; Aged; Aldosterone; Black People; Blood Pressure; Female; Humans; Hypertension; M | 1982 |
Hormonal changes associated with hypertension in neoplasia-induced hypercalcemia.
Topics: Aldosterone; Animals; Calcium; Hormones; Hypercalcemia; Hypertension; Leydig Cell Tumor; Male; Norep | 1982 |
Exchangeable sodium and saralasin-blocking, plasma renin and aldosterone in pre- and postoperative young patients with aortic coarctation.
Topics: Adolescent; Aldosterone; Angiotensin II; Aortic Coarctation; Child; Humans; Hypertension; Natriuresi | 1982 |
Discrimination of renovascular from essential hypertension by converting enzyme inhibition with an orally active compound.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Diagnosis, Diffe | 1982 |
Renal function and hemodynamic studies in low- and normal-renin essential hypertension.
Topics: Adult; Aldosterone; Glomerular Filtration Rate; Humans; Hypertension; Inulin; Kidney; Male; Metaboli | 1982 |
Response of the systemic pulmonary circulation to labetalol at rest and during exercise.
Topics: Adult; Aldosterone; Ethanolamines; Female; Hemodynamics; Humans; Hypertension; Labetalol; Male; Phen | 1982 |
Captopril treatment: inter-dose variations in renin, angiotensins I and II, aldosterone and blood pressure.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Female; Hu | 1982 |
Hormonal pattern during development of hypertension in spontaneously hypertensive rats (SHR).
Topics: Aldosterone; Animals; Blood Pressure; Dinoprostone; Dopamine; Hormones; Hypertension; Norepinephrine | 1982 |
Aldosterone responsiveness to angiotensin II after sodium restriction in subjects with low renin essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hyperte | 1982 |
The role of urinary PGE2 and renin-angiotensin-aldosterone system in the pathogenesis of essential hypertension.
Topics: Adult; Aldosterone; Creatinine; Dinoprostone; Female; Furosemide; Glomerular Filtration Rate; Humans | 1982 |
[Endocrinological analysis of etiology of essential hypertension (author's transl)].
Topics: Adult; Aged; Aging; Aldosterone; Catecholamines; Humans; Hypertension; Middle Aged; Renin; Renin-Ang | 1982 |
Relation of arterial pressure with body sodium, body potassium and plasma potassium in essential hypertension.
Topics: Adult; Age Factors; Aldosterone; Angiotensin II; Blood Pressure; Body Surface Area; Body Weight; Hum | 1982 |
[The renin-aldosterone system in the diagnosis of essential hypertension].
Topics: Adult; Aldosterone; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin | 1982 |
[A decreased metabolic clearance rate of aldosterone in low-renin essential hypertension (author's transl)].
Topics: Adult; Aldosterone; Humans; Hypertension; Metabolic Clearance Rate; Middle Aged; Renin | 1982 |
An unusual case of hypertension with hypokalaemia.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Hypokalemia; Renin | 1982 |
Dopaminergic regulation of circadian rhythms of blood pressure, renin and aldosterone in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Bromocriptine; Circadian Rhythm; Dopamine; Humans; Hypertension; | 1982 |
Primary aldosteronism associated with a primary double cancer of the thyroid and rectum: report of a case.
Topics: Adenocarcinoma; Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hyperten | 1981 |
Low-renin, low-aldosterone hypertension and abnormal cortisol metabolism in a 19-month-old child.
Topics: Aldosterone; Cortisone; Dexamethasone; Follow-Up Studies; Furosemide; Humans; Hydrocortisone; Hypert | 1982 |
[Renin-angiotensin-aldosterone system and glucocorticoids in arterial hypertension].
Topics: Aldosterone; Glucocorticoids; Humans; Hydrocortisone; Hypertension; Hypertension, Renovascular; Pyel | 1982 |
Blood pressure in relation to the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Analysis of Variance; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Middl | 1982 |
Direct radioimmunoassays for "aldosterone" and "18-hydroxycorticosterone" in unprocessed urine, and their use in screening to distinguish primary aldosteronism from hypertension.
Topics: 18-Hydroxycorticosterone; Aldosterone; Corticosterone; Diagnosis, Differential; Female; Humans; Hype | 1982 |
[Fundamental and clinical studies on measurement of serum aldosterone by solid phase (author's transl)].
Topics: Adult; Aged; Aldosterone; Humans; Hypertension; Middle Aged; Radioimmunoassay; Reagent Kits, Diagnos | 1982 |
[Role of the angiotensin-aldosterone mechanism in the formation of Pulmonogenic arterial hypertension].
Topics: Aldosterone; Angiotensin I; Angiotensins; Chronic Disease; Humans; Hypertension; Hypertension, Pulmo | 1982 |
Role of adrenal steroidogenesis in etiology of hypertension in the spontaneously hypertensive rat.
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Glands; Aging; Aldosterone; Animals; Body Weight; Corticoste | 1982 |
The vasoconstriction-volume spectrum in normotension and in the pathogenesis of hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Blood Volume; Dogs; Humans; Hypertension; Hypertension, Malign | 1982 |
Parallel adrenal and renal abnormalities in young patients with essential hypertension.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Diuresis; Female; Hemod | 1982 |
[Hypokalemic myopathy in arterial hypertension].
Topics: Adult; Aged; Aldosterone; Diuretics; Fluprednisolone; Glycyrrhiza; Humans; Hypertension; Hypokalemia | 1982 |
Allantoxanamide-induced myocardial necrosis in Sprague-Dawley vs spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Corticosterone; Female; He | 1982 |
Acromegaly and hypertension: role of the renin-angiotensin-aldosterone system.
Topics: Acromegaly; Adult; Aged; Aldosterone; Blood Pressure; Female; Furosemide; Humans; Hypertension; Male | 1982 |
Proceedings of the symposium Mineralocorticoids in Essential and Secondary Hypertension. Newport Beach, California, February 28, 1982.
Topics: Aldosterone; Animals; Humans; Hypertension; Mineralocorticoids | 1982 |
The mineralocorticoid hormone pathways in hypertension with hyperaldosteronism.
Topics: 18-Hydroxydesoxycorticosterone; Adenoma; Aldosterone; Corticosterone; Desoxycorticosterone; Hydrocor | 1982 |
Hypersecretion of a new corticosteroid, 18-hydroxycortisol in two types of adrenocortical hypertension.
Topics: Adenoma; Adrenal Cortex; Aldosterone; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension | 1982 |
Aldosterone, sodium and potassium in essential hypertension.
Topics: Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Potassium; Reference Val | 1982 |
["Volume-dependent" form of hypertension].
Topics: Aldosterone; Blood Pressure; Body Water; Cardiac Output; Extracellular Space; Female; Humans; Hypert | 1982 |
[Diagnosis and surgical treatment of adrenal forms of symptomatic arterial hypertension].
Topics: Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Glucocortic | 1982 |
The Yucatan miniature swine: an improved pig model for the study of desoxycorticosterone-acetate (DOCA) and aldosterone hypertension.
Topics: Aldosterone; Animals; Desoxycorticosterone; Disease Models, Animal; Hypertension; Swine | 1982 |
Altered arterial ion transport and its reversal in aldosterone hypertensive rat.
Topics: Aldosterone; Animals; Arteries; Biological Transport, Active; Blood Pressure; Hypertension; Ions; Ma | 1982 |
Differences in adrenal cholesterol, ascorbic acid, circulating corticosterone and aldosterone during the onset of hypertension in SHR vs WKy rats.
Topics: Adrenal Glands; Aldosterone; Animals; Ascorbic Acid; Cholesterol; Corticosterone; Hypertension; Male | 1982 |
Plasma aldosterone concentrations in neonatal spontaneously hypertensive rats.
Topics: Age Factors; Aldosterone; Animals; Animals, Newborn; Hypertension; Rats | 1982 |
[Effects of passive semiorthostatic cardiopulmonary hematic centralization (by immersion in water) on hydrosaline elimination and on the renin-angiotensin-aldosterone system in essential hypertension].
Topics: Adolescent; Adult; Aged; Aldosterone; Cardiovascular System; Creatinine; Diuresis; Humans; Hypertens | 1982 |
Long term spironolactone and the adrenal cortex in essential hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex; Adult; Aged; Aldosterone; Cosyntropin; Female; Human | 1980 |
Hypersensitivity of spontaneously hypertensive rats (SHR) to heat, ether, and immobilization.
Topics: Aldosterone; Animals; Blood Glucose; Corticosterone; Ether; Ethyl Ethers; Female; Growth Hormone; Ho | 1981 |
Changes in the morphology and location of arterial lesions in virgin and breeder Sprague-Dawley and spontaneously hypertensive rats (SHR) to adrenal regeneration hypertension.
Topics: Adrenal Glands; Aldosterone; Animals; Aorta; Aortic Diseases; Arterioles; Arteriosclerosis; Blood Pr | 1980 |
Circadian rhythm of circulating aldosterone in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Circadian Rhythm; Female; Hypertension; Male; Rats; Sex Factors | 1981 |
[Determination of urinary 3 alpha, 5 beta-tetrahydroaldosterone as a parameter of aldosterone secretion in hypersensitive patients (author's transl)].
Topics: Aldosterone; Humans; Hypertension; Radioimmunoassay | 1981 |
[14C-aldosterone binding by plasma proteins in adolescents with primary arterial hypertension].
Topics: Adolescent; Aldosterone; Blood Proteins; Carbon Radioisotopes; Humans; Hyperaldosteronism; Hypertens | 1981 |
Blood levels of ethynylestradiol, caffeine, aldosterone and desoxycorticosterone in hypertensive oral contraceptive users.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Caffeine; Contraceptives, Oral; Desoxycorticosterone | 1981 |
Mineralocorticoid and hypertensive effects of 19-nor-progesterone.
Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Body Temperature; Body Weight; Drinking; Female | 1981 |
[Preoperative management of 461 hypertensive women].
Topics: Adult; Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Genital Diseases, Female; | 1981 |
Cyproheptadine in idiopathic aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cyproheptadine; Dexamethasone; Drug Synergism; Humans | 1981 |
Propranolol-induced alterations in the pathophysiology of spontaneously hypertensive rats.
Topics: Aging; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Corticosterone; F | 1981 |
[Excretion of free aldosterone fraction in adolescents with hypertension].
Topics: Adolescent; Aldosterone; Child; Glucuronates; Humans; Hypertension | 1981 |
The role of aldosterone in the development of hypertension in spontaneously hypertensive rats.
Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Creatinine; Hypertension; Kidney; Male; Potassi | 1981 |
[Estimation of the urinary aldosterone (author's transl)].
Topics: Aldosterone; Humans; Hypertension; Kidney Diseases; Liver Diseases; Radioimmunoassay; Reagent Kits, | 1981 |
[A direct radioimmunoassay determination of plasma aldosterone concentration in normal subjects and patients with hypertension or renal disease using 125I-labeled ligand (ALDOCTK-125 Kit) (author's transl)].
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Radioimmunoass | 1981 |
Characteristics of aldosterone binding in human plasma.
Topics: Aldosterone; Carrier Proteins; Humans; Hydrocortisone; Hypertension; Kinetics; Transcortin | 1980 |
Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.
Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Bendroflumethiazide; Bicarbonates; Blood Pressure; Di | 1980 |
Primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Posture | 1980 |
Effects of propranolol on aldosterone plasma concentration and aldosterone metabolic clearance in hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Metabolic Clearance Rate; Mi | 1980 |
[Measurement of percent uptake in the adrenal glands with 131I-adosterol (author's transl)].
Topics: Adosterol; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Cushing Syndrome; Humans; Hypertens | 1980 |
Hyperaldosteronism, hyperparathyroidism, medullary sponge kidneys, and hypertension.
Topics: Adenoma; Adult; Aldosterone; Blood Pressure; Female; Humans; Hyperaldosteronism; Hyperparathyroidism | 1980 |
[A simple method for measuring aldosterone secretion rate using 125I-aldosterone (authors' transl)].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hyperthyroidism; Iodine Radioisotopes; Radioi | 1980 |
Deoxycorticosterone and aldosterone clearance and binding in normal and hypertensive man.
Topics: Adult; Aldosterone; Desoxycorticosterone; Humans; Hypertension; Metabolic Clearance Rate; Middle Age | 1980 |
[Role of mineralocorticoid regulation of vascular reactivity in the arterial pressure reaction to increased salt uptake in healthy persons].
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Vessels; Dose-Response Relationship, Drug; | 1980 |
[Hypotensive effect of spironolactone in patients with essential hypertension and aldosterone regulation disorders].
Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Spironolactone | 1980 |
Increased 18-hydroxycorticosterone responses to frusemide in essential hypertension.
Topics: 18-Hydroxycorticosterone; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Corticosterone; Female | 1980 |
Regulation of serum-progesterone in patients with essential hypertension.
Topics: Adult; Aged; Aldosterone; Circadian Rhythm; Diet, Sodium-Restricted; Humans; Hypertension; Hypertens | 1980 |
Urinary tetrahydroaldosterone and aldosterone-18-glucuronide excretion in white and black normal subjects and hypertensive patients.
Topics: Adult; Aldosterone; Black People; Diet; Female; Glucuronates; Humans; Hyperaldosteronism; Hypertensi | 1981 |
Circadian blood pressure variation versus renal function.
Topics: Aldosterone; Black People; Blood Pressure; Circadian Rhythm; Creatinine; Heart Rate; Humans; Hyperte | 1995 |
Ca(2+)-dependent K+ current in arterial smooth muscle cells from aldosterone-salt hypertensive rats.
Topics: Aldosterone; Animals; Arteries; Caffeine; Calcium; Calcium Channel Blockers; Charybdotoxin; Electric | 1995 |
[Conceptual basis and diagnosis of primary hyperaldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hyper | 1995 |
Biological determinants of aldosterone-induced cardiac fibrosis in rats.
Topics: Aldosterone; Animals; Blotting, Northern; Collagen; Fibrosis; Heart; Histocytochemistry; Hypertensio | 1995 |
[Conn's adenoma. Diagnostic and prognostic value of the measurement of potassium, renin, aldosterone levels and the aldosterone/renin ratio].
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potassium; | 1995 |
[Hyperaldosteronism sensitive to dexamethasone with adrenal adenoma. Clinical, biological and genetic study].
Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Dexamethasone; Fem | 1995 |
Effect of the new calcium antagonist (+/-)-(R*)-3-[(R*)-1-benzyl-3- piperidyl] methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5- pyridinedicarboxylate hydrochloride (KW-3049) on cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegal | 1993 |
Hormonal, renal, and metabolic alterations during hypertension induced by chronic inhibition of NO in rats.
Topics: Aldosterone; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Creatinine; Diuresis; Do | 1994 |
Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome.
Topics: Adolescent; Adult; Aldosterone; Alleles; Amino Acid Sequence; Animals; Base Sequence; Codon; Epithel | 1995 |
Central obesity and hypertension: pathophysiologic role of renal haemodynamics and function.
Topics: Adult; Albuminuria; Aldosterone; Body Constitution; Body Mass Index; Cardiac Output; Female; Glomeru | 1995 |
Left ventricular mass in hereditary human hypertension: glucocorticoid-suppressible hyperaldosteronism.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Child; Female; Genotype; Glucocorticoids; Humans; Hy | 1995 |
In vivo pharmacology of L-159,913, a new highly potent and selective nonpeptide angiotensin II receptor antagonist.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Bip | 1995 |
Phorbol ester-stimulated 6-keto-prostaglandin F1 alpha in aortas from control and aldosterone-salt rats.
Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Alkaloids; Animals; Aorta; Calcium; Dose-Response Relatio | 1995 |
[Evaluation of the efficacy and safety of monotherapy for significant essential hypertension in adolescents with use of enalapril].
Topics: Adolescent; Aldosterone; Child; Echocardiography; Enalapril; Evaluation Studies as Topic; Female; Ga | 1995 |
Hypertension in cyclosporin A-treated patients is independent of circulating endothelin levels.
Topics: Adult; Aldosterone; Arthritis, Rheumatoid; Atrial Natriuretic Factor; Blood Pressure; Cyclosporine; | 1995 |
Attenuated Ca2+ response to acetylcholine in endothelial cells from aorta of aldosterone-salt hypertensive rats.
Topics: Acetylcholine; Aldosterone; Animals; Arginine; Calcium; Endothelium, Vascular; Fura-2; Hypertension; | 1995 |
Acute effects of flosequinan (BTS 49465) in untreated moderate to severe hypertension.
Topics: Administration, Oral; Adult; Aldosterone; Epinephrine; Female; Hemodynamics; Humans; Hypertension; M | 1995 |
The Bergen Blood Pressure Study: inappropriately low levels of circulating atrial natriuretic peptide in offspring of hypertensive families.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Catecholamines; Family; Female; Human | 1994 |
Glucocorticoids but not mineralocorticoids modulate endothelin-1 and angiotensin II binding in SHR vascular smooth muscle cells.
Topics: Aldosterone; Androstanols; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compo | 1995 |
The role of potassium in postural hypotension: electrolytes and neurohumoral factors in elderly hypertensive patients using diuretics.
Topics: Aged; Aged, 80 and over; Aldosterone; Atrial Natriuretic Factor; Case-Control Studies; Cross-Section | 1995 |
11 beta-Hydroxysteroid dehydrogenase and its inhibitors in hypertensive pregnancy.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Blood Pressure; Female; Humans; Hydrocort | 1995 |
Angiotensin and bradykinin peptides in the TGR(mRen-2)27 rat.
Topics: Aldosterone; Amino Acid Sequence; Angiotensin II; Animals; Animals, Genetically Modified; Bradykinin | 1995 |
Angiotensin peptides in spontaneously hypertensive and normotensive Donryu rats.
Topics: Adipose Tissue, Brown; Adrenal Glands; Aldosterone; Angiotensins; Animals; Brain Chemistry; Hyperten | 1995 |
Renal and adrenal sparing surgery for patients with primary aldosteronism and primary reninoma.
Topics: Adenocarcinoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans | 1995 |
Aldosterone and testosterone producing adrenal adenoma in childhood.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Child; Humans; Hypertension; Male; Nephrocalcinosis; | 1995 |
Clinical evidence for an association between left ventricular geometric adaptation and extracardiac target organ damage in essential hypertension.
Topics: Aldosterone; Catecholamines; Cholesterol; Creatinine; Female; Humans; Hypertension; Hypertrophy, Lef | 1995 |
Atrial natriuretic peptide and antihypertensive action due to beta-blockade in essential hypertensive patients.
Topics: Adrenergic beta-Antagonists; Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; | 1995 |
Renal, endocrine and vascular effects of atrial natriuretic peptide in a novel vasopressin-deficient genetically hypertensive strain of rat.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Disease Models, Ani | 1995 |
Aldosterone and Hypertension. Proceedings of a satellite symposium to the 15th International Society of Hypertension Congress. Lorne, Victoria, Australia, March 17-19, 1994.
Topics: Aldosterone; Animals; Blood Pressure; History, 20th Century; Humans; Hyperaldosteronism; Hypertensio | 1995 |
Differences in temperature-sensitive receptor binding of glucocorticoids in spontaneously hypertensive and normotensive Wistar-Kyoto rats.
Topics: Aldosterone; Animals; Corticosterone; Dexamethasone; Hypertension; Male; Radioligand Assay; Rats; Ra | 1995 |
Exaggerated blood pressure response to angiotensin II in patients with Cushing's syndrome due to adrenocortical adenoma.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Cu | 1994 |
Screening of a population of young hypertensives for primary hyperaldosteronism.
Topics: Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Middle Aged; Renin | 1994 |
Nonmodulating trait may precede the development of hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Dopamine; Humans; Hypertension; Infusions, | 1994 |
Renin-sodium profile and renal prostaglandins in the pathogenesis of systemic arterial hypertension in blacks.
Topics: Adult; Aldosterone; Black People; Female; Humans; Hypertension; Kidney; Potassium; Prostaglandins; R | 1994 |
Hypertension and the mineralocorticoid receptor in the brain.
Topics: Adrenalectomy; Aldosterone; Amiloride; Animals; Blood Pressure; Brain; Cerebral Ventricles; Hippocam | 1994 |
Renin and aldosterone are higher and the hyperinsulinemic effect of salt restriction greater in subjects with risk factors clustering.
Topics: Adult; Aldosterone; Anthropometry; Blood Pressure; Cluster Analysis; Coronary Disease; Diet; Diet, S | 1994 |
Relationships among plasma aldosterone, high-density lipoprotein cholesterol, and insulin in humans.
Topics: Adult; Aldosterone; Blood Pressure; Cholesterol, HDL; Female; Humans; Hypertension; Insulin; Male; M | 1995 |
The impaired control of plasma renin activity in hypertensive patients with end-stage renal disease due to chronic glomerulonephritis.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Glomerulonephritis; Humans; H | 1994 |
19-Hydroxyandrostenedione amplifies the hypertensive action of mineralocorticoids in rats.
Topics: Aldosterone; Androstenedione; Animals; Blood Pressure; Desoxycorticosterone; Dose-Response Relations | 1993 |
Role of glucocorticoid in the development of glycyrrhizin-induced hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Blood Pr | 1994 |
Angiotensin II type 1 receptor messenger RNA levels in human blood cells of patients with primary and secondary hypertension: reference to renin profile.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Base Sequence; Blood Platelets; Blotting, Northe | 1994 |
Resolution of posttransplant hypertension after liver transplantation despite impaired glomerular filtration.
Topics: Adult; Aldosterone; Antihypertensive Agents; Epoprostenol; Female; Glomerular Filtration Rate; Hemod | 1994 |
Artificial mutations in P450c11AS (aldosterone synthase) can increase enzymatic activity: a model for low-renin hypertension?
Topics: Aldosterone; Animals; Base Sequence; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme System; Hyper | 1995 |
A new subset of mineralocorticoid hypertension with excess of 21-deoxyaldosterone and Kelly's-M1 steroid: clinical and morphological findings.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hypertension; Immunohistochemi | 1995 |
The serum angiotensinogen concentration and variants of the angiotensinogen gene in white and black children.
Topics: Adolescent; Adult; Aldosterone; Alleles; Angiotensinogen; Base Sequence; Black People; Blood Pressur | 1995 |
Role of the renin-angiotensin system in arterial hypertension secondary to acute unilateral urinary obstruction.
Topics: Aldosterone; Animals; Blood Pressure; Captopril; Disease Models, Animal; Dogs; Hypertension; Renin; | 1994 |
Role of 21-deoxyaldosterone in human hypertension.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Female; Humans; Hyperaldos | 1994 |
High incidence of primary aldosteronism in 199 patients referred with hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Female; Humans; Hyperaldosteronism; Hyperte | 1994 |
[Effect of captopril on adrenal gluco- and mineral-corticoid functions in the treatment of patients with hypertension].
Topics: 11-Hydroxycorticosteroids; Adrenal Glands; Adult; Aged; Aldosterone; Captopril; Female; Humans; Hype | 1993 |
Zona glomerulosa of the adrenal gland in a transgenic strain of rat: a morphologic and functional study.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Animals, Genetically Modified; Ce | 1994 |
[A case of idiopathic hyperaldosteronism with normal plasma aldosterone concentrations for 5 years after onset: a 12-year follow-up study].
Topics: Aldosterone; Diagnosis, Differential; Follow-Up Studies; Furosemide; Humans; Hyperaldosteronism; Hyp | 1994 |
The association between salt sensitivity of blood pressure and some polymorphic factors.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; DNA Transposable Elements; Drug R | 1994 |
The role of endogenous digitalis-like factor in blood pressure regulation in essential hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Blood Proteins; Cardenolides; Digoxin | 1994 |
The CSF aldosterone in brain tumors with brain edema.
Topics: Adolescent; Adult; Aged; Aldosterone; Astrocytoma; Blood-Brain Barrier; Brain Edema; Brain Neoplasms | 1994 |
Effect of central amiloride infusion on mineralocorticoid hypertension.
Topics: Aldosterone; Amiloride; Animals; Brain; Carbenoxolone; Diet; Hypertension; Injections, Intraventricu | 1994 |
Adrenal adenoma with primary aldosteronism in a child: a case report.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Child; Female; Humans; Hyperaldosteronism; Hypertensi | 1994 |
[Endocrinological and imaging analyses of adrenal incidentalomas with hypertension and/or diabetes mellitus].
Topics: 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Aged; Aldosterone; Carcinoma; Catecholamines; Cus | 1994 |
Cushing's disease: evaluation of mineralocorticoid-induced hypertension.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Corticosterone; Cushing Sy | 1993 |
Effect of an angiotensin II receptor antagonist, CV-11974, and its prodrug, TCV-116, on production of aldosterone.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin III; Ang | 1994 |
Hypertension induced by a nonpressor dose of angiotensin II in kininogen-deficient rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Heart Rate; Hypertension; Kininogens; Kinins; | 1994 |
Increased cardiac types I and III collagen mRNAs in aldosterone-salt hypertension.
Topics: Aldosterone; Animals; Collagen; Gene Expression; Hypertension; Male; Myocardium; Rats; Rats, Wistar; | 1994 |
[Changes in humoral pressor and depressor factors in essential hypertension during lisinopril therapy].
Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Female; Humans; Hypertension; Kallikreins; Lisin | 1994 |
The renal functional reserve in recently diagnosed essential hypertension.
Topics: Adult; Albuminuria; Aldosterone; Amino Acids; Catecholamines; Creatinine; Humans; Hypertension; Kidn | 1994 |
[Primary amenorrhea and arterial hypertension in a case of 17 alpha-hydroxylase deficiency].
Topics: Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Amenorrhea; Corticosterone; Desoxycorticosteron | 1994 |
Unilateral adrenal hypersecretion of both aldosterone and cortisol in two first cousins with a syndrome of mineralocorticoid excess but without signs of hypercortisolism.
Topics: Adrenal Glands; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hyperaldosteronism; Hyperplasia; | 1994 |
Role of insulin and norepinephrine in the hypertension of obesity.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Insulin; Male; Norepinephrine; Obesity; Renin; Wei | 1994 |
Effect of insulin on sodium reabsorption in hypertensive patients.
Topics: Absorption; Adult; Aldosterone; Blood Glucose; Blood Pressure; Glucose Clamp Technique; Humans; Hype | 1994 |
[Possible influence of hemodynamic and neurohormonal factors on the heart's response to arterial hypertension].
Topics: Adult; Aldosterone; Cardiomegaly; Female; Heart; Hemodynamics; Humans; Hypertension; Linear Models; | 1994 |
Abnormalities in the renin-angiotensin-aldosterone system in normotensive subjects with a positive family history of hypertension.
Topics: Aged; Aldosterone; Blood Pressure; Humans; Hypertension; Male; Medical Records; Middle Aged; Obesity | 1994 |
Blood pressure responses to dietary salt in rural and urban African men.
Topics: Adult; Aldosterone; Black People; Developing Countries; Diet, Sodium-Restricted; Humans; Hypertensio | 1993 |
Evidence of abnormalities in corticosteroid secretion leading to volume-dependent hypertension in Milan rats.
Topics: 18-Hydroxycorticosterone; Adrenal Glands; Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pre | 1994 |
Effects of long-term oral administration of NZ-105, a novel calcium antagonist, with or without propranolol in spontaneously hypertensive rats.
Topics: Administration, Oral; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel | 1993 |
Escape from the sodium-retaining effects of mineralocorticoids: is there a role for dopamine?
Topics: Adenoma; Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Dopamine; Female | 1994 |
Reduced left ventricular distensibility in normotensive men with a positive family history of hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Electrocardiography; Heart Rate; Humans; H | 1993 |
[Restructuring of the collagen network in hypertension: role of the angiotensin-aldosterone system].
Topics: Aldosterone; Animals; Collagen; Fibrosis; Humans; Hypertension; Hypertrophy, Left Ventricular; Renin | 1993 |
[Relationship of the renin-angiotensin-aldosterone system with auricular natriuretic factor in its response to the action of thiazide diuretics and to nifedipine, a sustained-release calcium antagonist].
Topics: Aldosterone; Amiloride; Animals; Ants; Blood Pressure; Delayed-Action Preparations; Female; Heart Ra | 1994 |
Treatment with lisinopril normalizes serum concentrations of procollagen type III amino-terminal peptide in patients with essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Echocardiography; Female; Humans; Hypertension; Lisinopril; Male | 1994 |
[Aldosterone and 11 beta-hydroxysteroid dehydrogenase: role in arterial hypertension].
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Humans; Hydroxysteroid Dehydrogenases; Hyperaldo | 1993 |
Association between extracellular volume expansion and urinary calcium excretion in normal humans.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Volume; Calcium; Extracellular Space; Female; H | 1993 |
Bioelectric impedance analysis of body composition in alcohol-related essential hypertension.
Topics: Adult; Alcoholism; Aldosterone; Body Composition; Body Water; Electric Impedance; Extracellular Spac | 1993 |
How common is primary aldosteronism? Is it the most frequent cause of curable hypertension?
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Australia; Female; Humans; Hyperaldosteronism; Hyperten | 1993 |
Acute sodium loading in patients with uncomplicated diabetes mellitus: renal and hormonal effects.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Diabetes Mellitus; Diabet | 1994 |
Sodium physiopathology and 'nonmodulating' hypertension.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Drug Resistance | 1994 |
Hyperkalemia due to hyporeninemic hypoaldosteronism with liver cirrhosis and hypertension.
Topics: Aldosterone; Captopril; Furosemide; Humans; Hyperkalemia; Hypertension; Hypoaldosteronism; Liver Cir | 1993 |
Decreased activity of 11 beta-hydroxysteroid dehydrogenase in mesenteric arteries of Dahl salt-sensitive rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aging; Aldosterone; Animals; Blood Pressure; Body Weight; Cor | 1994 |
Apparent mineralocorticoid excess type II.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Aldosterone; Cortisone; Dexamethasone; Fem | 1994 |
Circulatory and plasma catecholamine responses to mental stress in young subjects with two different types of hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Diastole; Epinephrine; Humans; Hypertension; Mal | 1994 |
Pathophysiological mechanisms of urbanisation-related hypertension and the sodium pressor response in black Zimbabweans.
Topics: Aldosterone; Black People; Blood Pressure; Endothelins; Epoprostenol; Female; Humans; Hypertension; | 1993 |
Cyclosporine-induced stimulation of the renin-angiotensin system after liver and heart transplantation.
Topics: Aldosterone; Analysis of Variance; Angiotensinogen; Blood Pressure; Cyclosporine; Heart Transplantat | 1993 |
Ambulatory blood pressure changes in the menstrual cycle of hypertensive women. Significance of plasma renin activity values.
Topics: Adult; Aldosterone; Blood Pressure Determination; Blood Pressure Monitors; Female; Gonadal Steroid H | 1993 |
Plasma levels of brain natriuretic peptide in healthy subjects and patients with essential hypertension: response to posture.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Female; Heart Rate; Humans; Hypertension; Male; Middl | 1993 |
Natriuretic and hypotensive effect of adenosine-1 blockade in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Cyclic AMP; Glomerular Filtration Rate; Heart Rate; Humans; Hype | 1993 |
[Role of aldosterone in essential arterial hypertension complicated by chronic renal insufficiency].
Topics: Adrenocorticotropic Hormone; Aged; Aldosterone; Blood Pressure; Cations; Creatinine; Female; Humans; | 1993 |
11 beta-Hydroxysteroid dehydrogenase activity in mesenteric arteries of spontaneously hypertensive rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Blood Pressure; Blotting, Northern; Bod | 1993 |
Water immersion and salt-sensitivity in essential hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Calcium; Diet; Extracellular Space; F | 1993 |
Nature of elevated blood pressure in normoalbuminuric type I diabetic patients. Essential hypertension?
Topics: Adolescent; Adult; Albuminuria; Aldosterone; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type | 1993 |
[Unilateral autonomous aldosterone production in hyperaldosteronism suppressible by dexamethasone].
Topics: Adrenal Cortex Hormones; Adult; Aldosterone; Dexamethasone; Female; Humans; Hydrocortisone; Hyperald | 1993 |
Left ventricular hypertrophy in asymptomatic essential hypertension: its relationship with aldosterone and the increase in sodium-proton exchanger activity.
Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Case-Control Studies; Erythrocytes; Female; Humans; | 1993 |
Renal response to amino acid infusion in essential hypertension.
Topics: Adult; Aged; Aldosterone; Amino Acids; Angiotensin II; Blood Pressure; Diastole; Diet, Sodium-Restri | 1994 |
Insulin sensitivity and the effects of insulin on renal sodium handling and pressor systems in essential hypertensive patients.
Topics: Aldosterone; Blood Pressure; Female; Glucose Clamp Technique; Heart Rate; Humans; Hypertension; Infu | 1994 |
The effect of prostaglandin E1 analog misoprostol on chronic cyclosporin nephrotoxicity.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Chronic Disease; Creatinine; Cyclos | 1993 |
Chronic pressure-natriuresis relationship in dogs with inherited essential hypertension.
Topics: Aldosterone; Analysis of Variance; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Blood P | 1993 |
The effect of low and high sodium diets on plasma atrial natriuretic factor, the renin-aldosterone system and blood pressure in subjects with essential hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Humans; Hypertension; Male; Middle Aged; Renin; Renin | 1994 |
Regulation of aldosterone secretion in hypertensive blacks.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Black People; Female; Humans; Hyper | 1994 |
Evidence that primary aldosteronism may not be uncommon: 12% incidence among antihypertensive drug trial volunteers.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hy | 1993 |
Primary aldosteronism: a new understanding.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi | 1993 |
Myocardial fibrosis in the rat with mineralocorticoid excess. Prevention of scarring by amiloride.
Topics: Aldosterone; Amiloride; Animals; Cardiomyopathies; Cicatrix; Collagen; Disease Models, Animal; Drug | 1993 |
Deficient inactivation of cortisol by 11 beta-hydroxysteroid dehydrogenase in essential hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Carbenoxolone; Cortisone; Female; Humans; | 1993 |
Effects of a calcium antagonist on the pituitary-adrenal axis.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure; Calcium Channel Blockers; Female; H | 1993 |
The angiotensin I converting enzyme gene and predisposition to high blood pressure.
Topics: Adult; Aldosterone; Alleles; Angiotensin II; Blood Pressure; Diastole; Family; Female; Genetic Predi | 1993 |
The role of glucocorticoid activity in the inheritance of hypertension: studies in the rat.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Hypertension; Male; Rats; Rats, I | 1993 |
[Effect of different amounts of dietary sodium on plasma atrial natriuretic peptide (ANP)in essential salt sensitive hypertension].
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Cyclic GMP; Female; Humans; Hypertension; Male; Renin | 1993 |
[Effect of intravenous sodium chloride load on levels of atrial natriuretic peptide (ANP) and 3'5' guanosine monophosphate (cGMP) in plasma of patients with uncomplicated sodium-sensitive arterial hypertension maintained on different dietary sodium intake
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Cyclic GMP; Female; Humans; Hypertension; Infusions, | 1993 |
The relationship between blood pressure and sodium and potassium excretion during the day and at night.
Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Monitors; Circadian Rhythm; Female; Humans; Hyper | 1993 |
Role of L-arginine-nitric oxide pathway in hypertension.
Topics: Adult; Aged; Aldosterone; Arginine; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; N | 1993 |
Evaluation of diagnostic tests in the differential diagnosis of primary aldosteronism: unilateral adenoma versus bilateral micronodular hyperplasia.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosteron | 1993 |
Exaggerated natriuresis induced by sodium chloride infusion in essential hypertension is accompanied by an exaggerated urinary 3' 5' guanosine monophosphate excretion.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Cyclic GMP; Female; Humans; Hypertension; Infusions, | 1993 |
Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Cardiomyopathies; Fibrosis; Hyperaldosteronism; Hypertension; | 1993 |
Influence of arterial blood pressure and aldosterone on left ventricular hypertrophy in moderate essential hypertension.
Topics: Adult; Aldosterone; Analysis of Variance; Blood Pressure; Female; Humans; Hypertension; Hypertrophy, | 1993 |
Effects of nitrendipine on blood pressure, renin-angiotensin-system and atrial natriuretic peptide in hypertensive type I diabetic patients.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Diabetes Mellitus, Type 1; Diab | 1993 |
Efficacy and mode of action of manidipine: a new calcium antagonist.
Topics: Adult; Aldosterone; Calcium; Calcium Channel Blockers; Dihydropyridines; Diuresis; Female; Hemodynam | 1993 |
Coronary microvascular fluid flux and permeability: influence of angiotensin II, aldosterone, and acute arterial hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Capillary Permeability; Coronary Vessels; Dogs; Female; Heart; | 1993 |
Renin-angiotensin-aldosterone system in healthy subjects aged ten to eighteen years.
Topics: Adolescent; Age Factors; Aldosterone; Black People; Child; Female; Humans; Hypertension; Male; Refer | 1993 |
Renin-angiotensin-aldosterone system and arterial hypertension following orthotopic liver transplantation.
Topics: Aldosterone; Humans; Hypertension; Liver Transplantation; Prospective Studies; Reference Values; Ren | 1993 |
Antihypertensive action of heparin: role of the renin-angiotensin aldosterone system and prostaglandins.
Topics: Aldosterone; Animals; Blood Pressure; Dinoprost; Epoprostenol; Hematocrit; Heparin; Hypertension; In | 1993 |
[Effect of aging on sensitivity of blood pressure to salt].
Topics: Adult; Aged; Aging; Aldosterone; Blood Pressure; Epinephrine; Female; Humans; Hypertension; Male; Mi | 1993 |
Sodium retention and hypertension after kidney transplantation in rats.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Cerebrovascular Disorders; Diet; Hypertension; Ki | 1993 |
Plasma big endothelin-1 concentrations in congestive heart failure patients with or without systemic hypertension.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Case-Control Studies; Endothelins; Female; Foll | 1993 |
Atrial natriuretic peptide in non-modulating essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Diet, Sodium-Restricted; Hormones; Hu | 1993 |
Effect of losartan, an angiotensin II receptor antagonist, on response of cortisol and aldosterone to adrenocorticotrophic hormone.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Ant | 1995 |
Alterations of calcium metabolism and of parathyroid function in primary aldosteronism, and their reversal by spironolactone or by surgical removal of aldosterone-producing adenomas.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Analysis | 1995 |
Dopamine D5 receptor expression is unchanged in peripheral blood lymphocytes in essential hypertension.
Topics: Adult; Aldosterone; Benzazepines; Catecholamines; Female; Humans; Hypertension; Lymphocytes; Male; M | 1995 |
Endogenous renal 11 beta-hydroxysteroid dehydrogenase inhibitory factors in patients with low-renin essential hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Chromatography, High Pressure Liquid; Die | 1996 |
[Mechanism of inhibition of aldosterone secretion by a Ca2+ channel blocker in patients with essential hypertension and patients with primary aldosteronism].
Topics: Adult; Aged; Aldosterone; Calcium Channel Blockers; Depression, Chemical; Female; Humans; Hyperaldos | 1995 |
Converting enzyme inhibition and its withdrawal in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinoge | 1995 |
Immunoreactive endogenous ouabain in primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels.
Topics: Aldosterone; Blood Pressure; Dihydroergotoxine; Dopamine Agonists; Dopamine Antagonists; Female; Hum | 1995 |
Nocturnal blood pressure elevation is related to adrenomedullary hyperactivity, but not to hyperinsulinemia, in nonobese normoalbuminuric type 1 diabetes.
Topics: Adolescent; Adrenal Medulla; Adult; Albuminuria; Aldosterone; Body Mass Index; Circadian Rhythm; Dia | 1996 |
Chronic ouabain infusion does not cause hypertension in sheep.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood | 1996 |
Prevalence of adrenal and extra-adrenal Conn syndrome in hypertensive patients.
Topics: Adrenal Cortex Neoplasms; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; | 1996 |
Angiotensin converting enzyme gene I/D polymorphism, blood pressure and the renin-angiotensin system in Caucasian and Afro-Caribbean peoples.
Topics: Adult; Africa; Aldosterone; Alleles; Black People; Blood Pressure; Caribbean Region; Female; Gene Fr | 1996 |
[Adrenal adenoma or hyperplasia? Problems of differential diagnosis in an unusual case of primary hyperaldosteronism].
Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Diagnosis, | 1996 |
[Plasma renin activity, aldosterone and adrenergic activity in patients with hypertension and in normotensives with a family history of hypertension].
Topics: Adolescent; Adult; Aldosterone; Catecholamines; Exercise; Humans; Hypertension; Male; Renin; Stress, | 1996 |
Adrenal tumor producing 11-deoxycorticosterone, 18-hydroxy-11-deoxycorticosterone and aldosterone.
Topics: 18-Hydroxydesoxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Aldosterone; Desoxycorticosterone; | 1996 |
Influence of humoral and neurohormonal factors on cardiovascular hypertrophy in untreated essential hypertensives.
Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Blood Pressure Monito | 1996 |
Does industrial environment influence the prevalence of arterial hypertension, plasma cholesterol and uric acid concentration and activity of the renin-aldosterone system?
Topics: Adult; Aldosterone; Cholesterol; Environmental Monitoring; Environmental Pollution; Epidemiological | 1996 |
Sodium status, corticosteroid metabolism and blood pressure in normal human subjects and in a patient with abnormal salt appetite.
Topics: Adrenal Cortex Hormones; Adult; Aldosterone; Angiotensin II; Appetite; Female; Humans; Hydroxysteroi | 1996 |
Effects of hyperinsulinaemia on renal function and the pressor system in insulin-resistant obese adolescents.
Topics: Adolescent; Adrenergic alpha-Agonists; Aldosterone; Glucose Clamp Technique; Humans; Hypertension; I | 1996 |
[Features of endocrine function changes in hypertensive NISAG line rats after exposure to adrenaline].
Topics: Adrenergic Agonists; Aldosterone; Animals; Corticosterone; Endocrine Glands; Epinephrine; Hypertensi | 1996 |
Physiological significance of plasma sulfoconjugated dopamine in patients with hypertension--clinical and experimental studies.
Topics: Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure | 1996 |
Modifications induced by -10 degrees Trendelenburg's posture in sodium tubular handling in patients with essential hypertension.
Topics: Adult; Aldosterone; Body Mass Index; Dinoprostone; Epinephrine; Female; Head-Down Tilt; Humans; Hype | 1996 |
Aldosterone action, sodium channels and inherited disease.
Topics: Aldosterone; Epithelium; Humans; Hypertension; Hypokalemia; Metabolism, Inborn Errors; Mineralocorti | 1996 |
Effect of central muscarine receptor blockade with DKJ-21 on the blood pressure and heart rate in stress-induced hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Corticosterone; Female; Heart Rate; Hypertension; Male; Muscar | 1996 |
Fluid, ionic and hormonal changes induced by high salt intake in salt-sensitive and salt-resistant hypertensive patients.
Topics: Aldosterone; Atrial Natriuretic Factor; Blood Glucose; Calcium; Cholesterol; Cholesterol, LDL; Creat | 1996 |
Urinary calcium excretion in treated and untreated essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Antihypertensive Agents; Benzothiadiazines; Blood G | 1996 |
Renal functional reserve in kidney and heart transplant recipients.
Topics: Adult; Aldosterone; Amino Acids; Azathioprine; Creatinine; Cyclosporine; Female; Glomerular Filtrati | 1996 |
Ethnic differences of renin-sodium profile and renal prostaglandins in the pathogenesis of systemic arterial hypertension.
Topics: Adult; Aldosterone; Black People; Case-Control Studies; Dinoprost; Dinoprostone; Female; Humans; Hyp | 1996 |
Primary hyperaldosteronism: a missed diagnosis in 'essential hypertensives'?
Topics: Adult; Aldosterone; Biomarkers; Case-Control Studies; Diagnosis, Differential; Female; Humans; Hyper | 1996 |
Fluid homeostasis after heart transplantation: the role of cardiac denervation.
Topics: Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Denervation; Electrolytes; Female; Hea | 1996 |
Modulation of target tissue response to angiotensin II and sodium sensitivity in Japanese patients with essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Infusions, Intrave | 1996 |
Clinical, biochemical and genetic approaches to the detection of familial hyperaldosteronism type I.
Topics: Adolescent; Adult; Aged; Aldosterone; Base Sequence; Blood Pressure; Blotting, Southern; Child; DNA; | 1995 |
Albuminuria in untreated patients with primary aldosteronism or essential hypertension.
Topics: Albuminuria; Aldosterone; beta 2-Microglobulin; Female; Humans; Hyperaldosteronism; Hypertension; Ma | 1995 |
Chronic carvedilol reduces mortality and renal damage in hypertensive stroke-prone rats.
Topics: Adrenergic beta-Antagonists; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Body Wei | 1996 |
Alpha-fluoromethylhistidine, an inhibitor of histamine biosynthesis, causes arterial hypertension.
Topics: Aldosterone; Analysis of Variance; Animals; Behavior, Animal; Blood Pressure; Catecholamines; Heart | 1996 |
[Aldosterone precursors and hypertension with hypokalemia and adrenal module non caused by primary hyperaldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Diagnosis, Differential; Female; Humans; | 1996 |
The role of intermediate phenotypes in essential hypertension: non-modulation as a model.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Blood Flow Velocity; Genotype | 1996 |
The resistance of the Wistar/Furth rat strain to steroid hypertension.
Topics: Adenosine Triphosphatases; Aldosterone; Animals; Desoxycorticosterone; Dexamethasone; Gene Expressio | 1996 |
11 beta-Hydroxylase activity in glucocorticoid suppressible hyperaldosteronism: lessons for essential hypertension?
Topics: Adrenocorticotropic Hormone; Aldosterone; Chimera; Corticosterone; Cortodoxone; Cytochrome P-450 CYP | 1996 |
Regulation of 11 beta-hydroxylase cytochrome p450 expression by cholesterol in spontaneously hypertensive rats.
Topics: Adrenal Cortex; Aldosterone; Animals; Cholesterol, Dietary; Cohort Studies; Corticosterone; Cytochro | 1995 |
Effect of chronic ethanol consumption on the atrial natriuretic system of spontaneously hypertensive rats.
Topics: Aging; Alcohol Drinking; Aldosterone; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Bloo | 1996 |
Effects of estrogen replacement therapy on the renin-angiotensin system in postmenopausal women.
Topics: Aged; Aldosterone; Analysis of Variance; Angiotensinogen; Estradiol; Estriol; Estrogen Replacement T | 1997 |
Effects of nifedipine treatment on the renin-angiotensin-aldosterone axis.
Topics: Aged; Aldosterone; Blood Pressure; Delayed-Action Preparations; Female; Humans; Hypertension; Male; | 1997 |
Structure and function of steroid dehydrogenases involved in hypertension, fertility, and cancer.
Topics: Aldosterone; Amino Acid Sequence; Binding Sites; Conserved Sequence; Cortisone Reductase; Crystallog | 1997 |
Liddle's syndrome: a 14-year follow-up of the youngest diagnosed case.
Topics: Aldosterone; Alkalosis; Blood Pressure; Child; Female; Follow-Up Studies; Growth; Humans; Hypertensi | 1997 |
Associations between circulating components of the renin-angiotensin-aldosterone system and left ventricular mass.
Topics: Age Factors; Aged; Aldosterone; Blood Pressure; Body Mass Index; Echocardiography; Female; Humans; H | 1997 |
Vascular aldosterone in genetically hypertensive rats.
Topics: Aldosterone; Animals; Blotting, Northern; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP | 1997 |
Increased Na(+)-H+ exchange in red blood cells of patients with primary aldosteronism.
Topics: Adrenal Gland Neoplasms; Adult; Age Factors; Aldosterone; Blood Pressure; Calmodulin; Erythrocytes; | 1997 |
An abnormal sodium metabolism in Japanese patients with essential hypertension, judged by serum sodium distribution, renal function and the renin-aldosterone system.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Ki | 1997 |
Left ventricular hypertrophy precedes other target-organ damage in primary aldosteronism.
Topics: Adult; Aged; Aldosterone; Electrocardiography; Female; Humans; Hyperaldosteronism; Hypertension; Hyp | 1997 |
[Hypertensive subpopulations as defined by their natriuretic response to ambulation].
Topics: Adult; Aged; Aldosterone; Catecholamines; Dinoprostone; Female; Humans; Hypertension; Kallikreins; M | 1997 |
Development of polyuria in Tsukuba hypertensive mice carrying human renin and angiotensinogen genes.
Topics: Aldosterone; Angiotensinogen; Animals; Electrolytes; Humans; Hyperaldosteronism; Hypertension; Kidne | 1995 |
Urinary excretion of 19-noraldosterone in the spontaneously hypertensive rat and stroke-prone spontaneously hypertensive rat.
Topics: Aldosterone; Animals; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Hypertension; | 1995 |
Renin-angiotensin system in the antihypertensive effect of isoteoline in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Antihypertensive Agents; Aporphines; Blood Pressure; Hypertension; In Vitro Te | 1995 |
Resistance to mineralocorticoids in Wistar-Furth rats.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Cells, Cultured; Citrate ( | 1997 |
Age, gender, and non-modulation. A sexual dimorphism in essential hypertension.
Topics: Adolescent; Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Data Interpretat | 1997 |
Liddle's syndrome: prospective genetic screening and suppressed aldosterone secretion in an extended kindred.
Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Female; Frameshift Mutation; Genetic Testing; | 1997 |
Serum gamma-glutamyl transferase levels and blood pressure falls after alcohol moderation.
Topics: Adult; Aged; Alcohol Drinking; Aldosterone; Blood Platelets; Blood Pressure; Calcium; Catecholamines | 1997 |
Remodeling of the left ventricle in primary aldosteronism due to Conn's adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Blood Flow Velocity; Coronary Circulatio | 1997 |
Genetic analysis of renin gene expression in the central nervous system of spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Brain Stem; Central Nervous System; DNA; Female; | 1997 |
Hypertensive cardiomegaly caused by an aldosterone-secreting adenoma in a newborn.
Topics: Adenoma; Adrenalectomy; Aldosterone; Cardiomegaly; Humans; Hyperaldosteronism; Hypertension; Infant; | 1997 |
[The morphofunctional characteristics of the zona glomerulosa of the adrenal cortex in rats with hereditary stress-induced arterial hypertension].
Topics: Aldosterone; Animals; Hypertension; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Rats, Wi | 1996 |
Effects of moxibustion on blood pressure and renal function in spontaneously hypertensive rats.
Topics: Acupuncture Points; Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Chlorides; Crea | 1997 |
Impact of the renin-angiotensin-aldosterone system on blood pressure response to intravenous enalaprilat in patients with hypertensive crises.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Emergencies; Enalaprilat; Female; Human | 1997 |
Lack of evidence for the interaction between renin-angiotensin-aldosterone system and endothelin in vivo.
Topics: Adult; Aldosterone; Antihypertensive Agents; Captopril; Endothelins; Endothelium; Humans; Hypertensi | 1996 |
Pharmacological profile of valsartan, a non-peptide angiotensin II type 1 receptor antagonist. 1st communication: antihypertensive effects of valsartan in hypertensive models.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertens | 1997 |
Left ventricular hypertrophy is more prominent in patients with primary aldosteronism than in patients with other types of secondary hypertension.
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Cushing Syndrome; Echocardiography; Female; Humans; Hyp | 1997 |
Influence of different dietary salts on the cardiovascular and renal effects of moxonidine in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Drinking; | 1997 |
Role of the renal kallikrein-kinin system in the development of hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Bradykini | 1997 |
Plasma renin activity in heart failure-prone SHHF/Mcc-facp rats.
Topics: Aging; Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Blood Volume; Disease Suscep | 1997 |
Mechanisms in the pressor effects of hepatic portal venous fatty acid infusion.
Topics: Acetylcholine; Aldosterone; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pre | 1997 |
Relationship between some humoral factors and left ventricular hypertrophy in essential hypertension.
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Midd | 1996 |
Autonomy of the renin system in type II diabetes mellitus: dietary sodium and renal hemodynamic responses to ACE inhibition.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitu | 1997 |
Sodium chloride and hypertension.
Topics: Aldosterone; Arteriosclerosis; China; Diet; Extracellular Space; Humans; Hypertension; Hypotonic Sol | 1997 |
Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Autoradiography; Binding Sites; Endomyocardial Fibrosis | 1997 |
The role of blood pressure and aldosterone in the production of hemorrhagic stroke in captopril-treated hypertensive rats.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cerebral | 1997 |
[Electrolyte metabolism and endocrine indices in the plasma and lymph of rats with hereditary arterial hypertension].
Topics: Aldosterone; Animals; Electrolytes; Hypertension; Insulin; Lymph; Male; Potassium; Rats; Rats, Wista | 1997 |
Effects of the glucocorticoid II receptor antagonist mifepristone on hypertension in the obese Zucker rat.
Topics: Aldosterone; Animals; Blood Pressure; Corticosterone; Hypertension; Male; Mifepristone; Obesity; Rat | 1997 |
Brain nitric oxide synthase messenger RNA in central mineralocorticoid hypertension.
Topics: Aldosterone; Animals; Brain; Hypertension; Injections, Intraventricular; Mineralocorticoids; Nitric | 1997 |
Long-term blockade of the angiotensin II receptor in renin transgenic rats, salt-loaded Dahl rats, and stroke-prone spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modifie | 1997 |
Evaluation of the dexamethasone suppression test for the diagnosis of glucocorticoid-remediable aldosteronism.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Cytochrome P-450 CYP11B2; Dexamethasone; Glucocorti | 1997 |
Role of renin-angiotensin-aldosterone system and of sympathetic activity in arterial hypertension associated with autosomal dominant polycystic kidney disease.
Topics: Aldosterone; Blood Pressure; Catecholamines; Female; Humans; Hypertension; Hypertension, Renal; Male | 1997 |
Dopamine D3 receptor in peripheral mononuclear cells of essential hypertensives.
Topics: Adult; Aldosterone; Binding, Competitive; Blood Pressure; Dopamine; Epinephrine; Female; Humans; Hyp | 1997 |
[A case of apparent mineralocorticoid excess caused by type 2 11 beta- hydroxysteroid dehydrogenase deficiency].
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Child, Preschool; Cortisone; Female; Humans; Hyd | 1997 |
[Cardio-protection and cardio-reparation in systemic arterial hypertension].
Topics: Aldosterone; Antihypertensive Agents; Electrocardiography; Humans; Hypertension; Hypertrophy, Left V | 1997 |
Coexisting renal artery stenosis and primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi | 1997 |
[Association between blood pressure and circulating hormonal factors with left ventricular mass in patients with essential hypertension older than 55 years of age].
Topics: Aged; Aldosterone; Cardiomegaly; Endothelin-1; Epinephrine; Female; Humans; Hypertension; Male; Midd | 1997 |
Association between increased plasma levels of aldosterone and decreased systemic arterial compliance in subjects with essential hypertension.
Topics: Adult; Aged; Aldosterone; Arteries; Compliance; Diltiazem; Hemodynamics; Humans; Hypertension; Male; | 1997 |
Endothelial dysfunction in hypertension is independent from the etiology and from vascular structure.
Topics: Acetylcholine; Adipose Tissue; Adrenal Gland Neoplasms; Aldosterone; Arterioles; Blood Pressure; Cho | 1998 |
Neurohormonal activity and left ventricular geometry in patients with essential arterial hypertension.
Topics: Aldosterone; Atrial Natriuretic Factor; Case-Control Studies; Echocardiography, Doppler; Female; Hea | 1998 |
Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo.
Topics: Actins; Aldosterone; Animals; Aorta, Thoracic; Carbachol; Cardiomegaly; Cell Cycle; DNA; Heart; Hype | 1998 |
[Alterations of calcium, magnesium, and zinc in essential hypertension:their relation to the renin-angiotensin-aldosterone system].
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Black People; Calcium; | 1997 |
Plasma atrial natriuretic peptide and natriuretic peptide receptor gene expression in adipose tissue of normotensive and hypertensive obese patients.
Topics: Actins; Adipose Tissue; Aldosterone; Atrial Natriuretic Factor; Biopsy, Needle; DNA Primers; Female; | 1997 |
Evidence for persistent dysfunction of wild-type aldosterone synthase gene in glucocorticoid-treated familial hyperaldosteronism type I.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Blotting, Southern; Cytochrome P-450 CYP11B2; | 1997 |
Circadian blood pressure variation in hypertensive patients with primary hyperaldosteronism.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; F | 1998 |
Renal functional reserve in IDDM patients.
Topics: Adult; Albuminuria; Aldosterone; Amino Acids; Blood Glucose; Blood Pressure; C-Peptide; Creatinine; | 1998 |
[Renin-aldosterone system in secretion of cortisol in patients with arterial hypertension in European North].
Topics: Adult; Aldosterone; Arctic Regions; Blood Pressure; Environmental Exposure; Humans; Hydrocortisone; | 1998 |
Opposite associations of circulating aldosterone and atrial natriuretic peptide with left ventricular diastolic function in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Coronary Circulation; Diastole; Echoc | 1998 |
[Hypertension treatable with glucocorticoids: report of a case].
Topics: Aldosterone; Dexamethasone; Female; Glucocorticoids; Humans; Hypertension; Middle Aged; Potassium; S | 1997 |
[Mutation T-->C of nucleotide 2238 in the gene of atrial natriuretic peptide (ANP) precursor and heterogeneity of sodium-sensitive hypertension. Preliminary report].
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Base Sequence; DNA; Female; Genotype; Humans; Hyperte | 1997 |
The diagnosis of Liddle syndrome by identification of a mutation in the beta subunit of the epithelial sodium channel.
Topics: Aldosterone; Alleles; Amino Acid Sequence; Base Sequence; Blood Pressure; Chromosome Mapping; Chromo | 1998 |
[Case of primary aldosteronism associated with heart and kidney failure].
Topics: Aldosterone; Biomarkers; Female; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Kidney Dis | 1998 |
Effects of dietary gamma-linolenic acid on blood pressure and adrenal angiotensin receptors in hypertensive rats.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone; Dietary Fats, | 1998 |
T235 variant of the angiotensinogen gene and blood pressure in the Chilean population.
Topics: Aldosterone; Angiotensinogen; Blood Pressure; Chile; DNA; DNA Primers; Female; Genotype; Humans; Hyp | 1998 |
Decreased blood pressure variability at rest in patients with primary aldosteronism.
Topics: Adult; Aldosterone; Baroreflex; Blood Pressure; Diastole; Exercise; Female; Heart Rate; Humans; Hype | 1998 |
Genetic determination of plasma aldosterone levels in essential hypertension.
Topics: Age Factors; Aldosterone; Biomarkers; Blood Flow Velocity; Blood Pressure; Body Height; Body Weight; | 1998 |
Molecular basis for hypertension in the "type II variant" of apparent mineralocorticoid excess.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Amino Acid Substitution; Base Sequence; B | 1998 |
Aldosterone overproduction and CYP11B2 mRNA overexpression in vessels of spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Aorta; Arteries; Cytochrome P-450 CYP11B2; Gene Expression; Hypertension; Mese | 1998 |
Associations between aldosterone synthase gene polymorphism and the adrenocortical function in males.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Analysis of Variance; Cohort Studie | 1998 |
Insulin resistance in essential hypertension is related to plasma renin activity.
Topics: Aged; Aldosterone; Blood Pressure; Female; Glucose Clamp Technique; Glucose Tolerance Test; Humans; | 1998 |
Modifications of myocardial Na+,K(+)-ATPase isoforms and Na+/Ca2+ exchanger in aldosterone/salt-induced hypertension in guinea pigs.
Topics: Aldosterone; Animals; Blotting, Northern; Blotting, Western; Echocardiography; Guinea Pigs; Hyperten | 1998 |
Aldosterone stimulates Na,K-ATPase activity in basolateral membrane of rat kidney.
Topics: Aldosterone; Animals; Binding Sites; Dactinomycin; Gene Expression Regulation, Enzymologic; Hyperten | 1998 |
Association between a polymorphism in the G protein beta3 subunit gene and lower renin and elevated diastolic blood pressure levels.
Topics: Aged; Aldosterone; Analysis of Variance; Anthropometry; Antihypertensive Agents; Blood Pressure; Coh | 1998 |
Differential catecholamine responses to protein intake in healthy and hypertensive subjects.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Dietary Prot | 1998 |
Vascular and neuroendocrine components in altered blood pressure regulation after surgical repair of coarctation of the aorta.
Topics: Adolescent; Adult; Aldosterone; Aortic Coarctation; Blood Flow Velocity; Blood Pressure; Child; Chil | 1998 |
Mutations in the carboxy terminus of the beta and gamma subunits of the epithelial sodium channel are not present in patients with hypertensive crisis.
Topics: Adult; Aged; Aldosterone; Amino Acid Sequence; Base Sequence; DNA; Emergencies; Female; Humans; Hype | 1998 |
Differential glucose tolerance in dipper and nondipper essential hypertension: the implications of circadian blood pressure regulation on glucose tolerance in hypertension.
Topics: Adult; Aldosterone; Autonomic Nervous System; Blood Glucose; Blood Pressure; Catecholamines; Cholest | 1998 |
Hormonal characteristics of primary aldosteronism due to unilateral adrenal hyperplasia.
Topics: Adrenal Cortex; Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldosteron | 1998 |
Structure-function relationships of aldosterone synthase and 11 beta-hydroxylase enzymes: implications for human hypertension.
Topics: 18-Hydroxycorticosterone; Aldosterone; Animals; COS Cells; Cytochrome P-450 CYP11B2; Humans; Hyperte | 1998 |
Aldosterone: a hormone with adverse autonomic effects?
Topics: Aldosterone; Animals; Autonomic Nervous System; Baroreflex; Cardiovascular System; Homeostasis; Huma | 1998 |
Renal effects of leptin in normotensive, hypertensive, and obese rats.
Topics: Aldosterone; Animals; Blood Pressure; Hemodynamics; Hypertension; Kidney; Leptin; Male; Obesity; Pro | 1998 |
Pressure-natriuresis and -diuresis in transgenic rats harboring both human renin and human angiotensinogen genes.
Topics: Aldosterone; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Diuresis; Huma | 1998 |
Hormonal response to orthostasis in elderly people with systemic systolic hypertension.
Topics: Aged; Aldosterone; Atrial Natriuretic Factor; Cardiac Output; Hemodynamics; Humans; Hypertension; Ma | 1998 |
In vivo left ventricular function and collagen expression in aldosterone/salt-induced hypertension.
Topics: Aldosterone; Animals; Collagen; Electrolytes; Fibrosis; Guinea Pigs; Hormones; Hypertension; Hypertr | 1998 |
Possible mechanisms of salt-induced hypertension in Dahl salt-sensitive rats.
Topics: Aldosterone; Animals; Aorta; Arginine Vasopressin; Blood Pressure; Body Weight; Cyclic GMP; Diet, So | 1998 |
Adrenal tumors and pregnancy.
Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Fatal Outc | 1999 |
Left ventricular systolic function in primary aldosteronism and hypertension.
Topics: Adult; Aldosterone; Echocardiography, Doppler; Female; Humans; Hyperaldosteronism; Hypertension; Hyp | 1998 |
Circadian variation of urinary microalbumin excretion and ambulatory blood pressure in patients with essential hypertension.
Topics: Adult; Aged; Albuminuria; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Blood Pressure Mon | 1998 |
Impaired baroreflex function and arterial compliance in primary aldosteronism.
Topics: Adult; Aldosterone; Arteries; Baroreflex; Blood Pressure; Compliance; Female; Heart Rate; Hemodynami | 1999 |
High and non-suppressible plasma renin activity in a patient with aldosterone producing adenoma: pathophysiologic and diagnostic implications.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Hypertension; Renin | 1999 |
Renal characteristics and effect of angiotensin suppression in oral contraceptive users.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressur | 1999 |
Genetic polymorphism of CYP11B2 gene and hypertension in Japanese.
Topics: Adult; Aged; Aldosterone; Amino Acid Substitution; Blood Pressure; Cytochrome P-450 CYP11B2; DNA; Fe | 1999 |
Potentially high prevalence of primary aldosteronism in a primary-care population.
Topics: Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Predictive Value of Tests | 1999 |
Low calorie diet enhances renal, hemodynamic, and humoral effects of exogenous atrial natriuretic peptide in obese hypertensives.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Diet; Diuresis; Female; Hemodynamics; Humans; Hyper | 1999 |
Aldosterone excretion rate and blood pressure in essential hypertension are related to polymorphic differences in the aldosterone synthase gene CYP11B2.
Topics: Adult; Aldosterone; Alleles; Blood Pressure; Cytochrome P-450 CYP11B2; Female; Genetic Linkage; Huma | 1999 |
Effects of the new angiotensin II type 1 receptor antagonist KRH-594 on several types of experimental hypertension.
Topics: Administration, Oral; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; | 1999 |
Adrenal cancer with hypertension but low plasma renin and aldosterone.
Topics: Adrenal Cortex Neoplasms; Adult; Aldosterone; Carcinoma; Female; Humans; Hypertension; Renin | 1999 |
[Relations between blood insulin concentration, renin-angiotensin-aldosterone system and clinical picture of hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Biomarkers; Blood Glucose; Blood Pressure; Echocardiography; Glu | 1999 |
Clinic-daytime blood pressure difference and cardiovascular damage.
Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carotid Arteries; Cholest | 1999 |
Hyponatremic-hypertensive syndrome with renal ischemia: an underrecognized disorder.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Female; Humans; Hypertension; Hyponatremia; Male; Middl | 1999 |
Epithelial sodium channel activity is not increased in hypertension in whites.
Topics: Adult; Aldosterone; Amiloride; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans; | 1999 |
Aldosterone directly induces Na, K-ATPase alpha 1-subunit mRNA in the renal cortex of rat.
Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Gene Expression Regulation, Enzymologic; Hypertensi | 1999 |
[Levels of biologically active substances in the blood of patients resistant and nonresistant to antihypertensive therapy].
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Drug Resistance; | 1999 |
Docosahexaenoic acid is an antihypertensive nutrient that affects aldosterone production in SHR.
Topics: Adrenal Glands; Aldosterone; Animals; Antihypertensive Agents; Arachidonic Acid; Blood Pressure; Cor | 1999 |
Beta-adrenergic receptor blockade as a therapeutic approach for suppressing the renin-angiotensin-aldosterone system in normotensive and hypertensive subjects.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme | 1999 |
Beta-adrenergic receptor blockade as a therapeutic approach for suppressing the renin-angiotensin-aldosterone system in normotensive and hypertensive subjects.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme | 1999 |
Beta-adrenergic receptor blockade as a therapeutic approach for suppressing the renin-angiotensin-aldosterone system in normotensive and hypertensive subjects.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme | 1999 |
Beta-adrenergic receptor blockade as a therapeutic approach for suppressing the renin-angiotensin-aldosterone system in normotensive and hypertensive subjects.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme | 1999 |
Adrenocortical activity in the newborn spontaneously hypertensive rat.
Topics: Adrenal Cortex; Aldosterone; Animals; Animals, Newborn; Biomarkers; Blood Pressure; Corticosterone; | 1999 |
Maternal hypertension and progeny blood pressure: role of aldosterone and 11beta-HSD.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Animals; Blood Pressure; Cerebral Ventric | 1999 |
Effects of cholic acid on blood pressure and production of vascular aldosterone and corticosterone.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aged; Aldosterone; Animals; Bile Acids and Salts; Bloo | 1999 |
Significance of sympathetic nervous system in sodium-induced nocturnal hypertension.
Topics: Aldosterone; Circadian Rhythm; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle A | 1999 |
Medical management of aldosterone-producing adenomas.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; | 1999 |
[Woman with refractory hypertension and hypokalemia].
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adrenocorticotrop | 1999 |
[Mineralocorticoid hypertension. A new form of secondary hypertension?].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoids; Renin; Renin-Angiotensin | 1999 |
Hyper-responsiveness to angiotensin II is related to cardiac structural adaptation in hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Hype | 1999 |
Primary aldosteronism in general practice.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; False Positive React | 1999 |
Aldosterone-producing adenoma without hypertension: a report of two cases.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure Moni | 1999 |
Vascular remodeling in hypertensive transgenic mice.
Topics: Aldosterone; Animals; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Blood Pressure; Disease M | 1999 |
Low-renin and nonmodulating essential hypertension.
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Renin; Sodium Channels; Vasoconstrictor Agents | 1999 |
Approach to a patient with suspected primary aldosteronism.
Topics: Aldosterone; Diagnosis, Differential; Female; Hematologic Tests; Humans; Hyperaldosteronism; Hyperte | 1999 |
Altered sodium perception in essential hypertensive patients following rapid volume expansion.
Topics: Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Dextrans; Female; | 1999 |
Genetic variants in the epithelial sodium channel in relation to aldosterone and potassium excretion and risk for hypertension.
Topics: Adolescent; Aldosterone; Black People; Blood Pressure; Cohort Studies; Epithelial Cells; Exons; Fema | 1999 |
A(-6)G variant of angiotensinogen gene and aldosterone levels in hypertensives.
Topics: Aged; Aldosterone; Angiotensinogen; Female; Gene Frequency; Humans; Hypertension; Male; Middle Aged; | 1999 |
Effect of poststroke captopril treatment on mortality associated with hemorrhagic stroke in stroke-prone rats.
Topics: Aldosterone; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Captopril; | 1999 |
Relation between the renin-angiotensin-aldosterone system and left ventricular structure and function in young normotensive and mildly hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin II; Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring, | 1999 |
[Left ventricular myocardial structure and function in patients with primary aldosteronism].
Topics: Adrenalectomy; Adult; Aldosterone; Blood Flow Velocity; Blood Pressure; Echocardiography, Doppler; F | 1999 |
Biochemical evidence of aldosterone overproduction and abnormal regulation in normotensive individuals with familial hyperaldosteronism type I.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Child; Dexamethasone; Female; Glucocorticoids; Homeo | 1999 |
[Hypertension plus hypokalemia should direct the line of thoughts toward Liddle's syndrome].
Topics: Adult; Aldosterone; Cataract; Diagnosis, Differential; Female; Humans; Hypertension; Hypokalemia; Im | 1999 |
[Mineralocorticoid-like hypertension. "Apparent mineralocorticoid excess". A hereditary type of hypertension?].
Topics: Adolescent; Adult; Aldosterone; Amiloride; Chromosome Aberrations; Chromosome Disorders; Diuretics; | 1999 |
A case of neurofibromatosis type 1 with an aldosterone-producing adenoma of the adrenal.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Causality; Female; Humans; Hypertension; Neuro | 1999 |
Prevalence of mild apparent mineralocorticoid excess in Mennonites.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Child; Christianity; Consanguinity; Female; Gene | 1999 |
Different platelet aggregability during mental stress in two stages of essential hypertension.
Topics: Adenosine Diphosphate; Adult; Aged; Aldosterone; beta-Thromboglobulin; Binding Sites; Biomarkers; Bl | 1999 |
Relation between dehydroepiandrosterone sulfate and blood pressure levels in a population-based sample.
Topics: Aged; Aldosterone; Androstenedione; Biomarkers; Blood Pressure; Dehydroepiandrosterone Sulfate; Fema | 1999 |
Platelet magnesium depletion in normotensive and hypertensive obese subjects: the role of salt-regulating hormones and catecholamines.
Topics: Adult; Aldosterone; Blood Platelets; Epinephrine; Female; Humans; Hypertension; Magnesium; Magnesium | 1999 |
Adrenocortical activity in fetal SHR and WKY rats.
Topics: Adrenal Cortex; Aldosterone; Animals; Corticosterone; Cytochrome P-450 Enzyme System; Female; Fetus; | 2000 |
Autonomic abnormalities demonstrable in young normotensive subjects who are children of hypertensive parents.
Topics: Adolescent; Adult; Aldosterone; Baroreflex; Blood Pressure; Body Mass Index; Chi-Square Distribution | 2000 |
[Animal experiment models of hypertension in pregnancy--an alternative to clinical studies?].
Topics: Aldosterone; Animals; Disease Models, Animal; Female; Hematocrit; Humans; Hypertension; Infant, Newb | 1999 |
[High prevalence of undiagnosed primary hyperaldosteronism among patients with essential hypertension].
Topics: Aldosterone; Comorbidity; Female; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Middl | 1999 |
Salt-induced exacerbation of morning surge in blood pressure in patients with essential hypertension.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Aldosterone; Baroreflex; Blood Pressure; Blood Pressure | 2000 |
Controlled study of circadian rhythm of blood pressure in patients with aldosterone-producing adenoma compared with those with essential hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Blood Pressure | 2000 |
[Features of dopaminergic system function in menopausal females with arterial hypertension].
Topics: Adult; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pressure; Bromocriptine; Dopamine; Do | 2000 |
Comment on "Interactions between endothelin-1 and the renin-angiotensin-aldosterone system".
Topics: Aldosterone; Animals; Animals, Genetically Modified; Endothelin Receptor Antagonists; Endothelin-1; | 1999 |
[Contemporary rules for diagnosing hypertension].
Topics: Aldosterone; Biomarkers; Blood Vessels; Elasticity; Humans; Hypertension; P-Selectin; Renin | 1999 |
Racial differences in response to acute dosing with hydrochlorothiazide.
Topics: Adult; Aldosterone; Black People; Blood Pressure; Circadian Rhythm; Diuretics; Dose-Response Relatio | 2000 |
[Changes in gluco- and mineralocorticoid adrenal functions in rats with inherited arterial hypertension during experimental myocardial infarction].
Topics: Adrenal Glands; Aldosterone; Animals; Corticosterone; Hypertension; Male; Myocardial Infarction; Rat | 2000 |
Plasma aldosterone concentrations are not related to the degree of angiotensin-converting enzyme inhibition in essential hypertensive patients.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Biomarkers; Blood Pressure; Ech | 2000 |
Medical management of aldosterone-producing adenomas.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension; Mineralocorticoid Receptor Anta | 2000 |
Role of dietary potassium in the hyperaldosteronism and hypertension of the remnant kidney model.
Topics: Aldosterone; Animals; Blood Pressure; Circadian Rhythm; Glomerular Filtration Rate; Hyperaldosteroni | 2000 |
Insulin action in primary hyperaldosteronism before and after surgical or pharmacological treatment.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Glucose; Glucose Clamp Technique; Glucos | 2000 |
Liddle's syndrome: a report in a middle-aged woman.
Topics: Aldosterone; Alkalosis; Female; Humans; Hypertension; Hypokalemia; Middle Aged; Renin; Syndrome | 2000 |
High prevalence of primary aldosteronism in the Tayside hypertension clinic population.
Topics: Adult; Aged; Aldosterone; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hypertension; Male; M | 2000 |
Defective suppression of the aldosterone biosynthesis during stroke permissive diet in the stroke-prone phenotype of the spontaneously hypertensive rat.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Hypertension; Japan; Male; Rats; Rats, Inbred SHR; | 2000 |
[Effect of coffee on blood pressure and activity renin-angiotensin- aldosterone system and catecholamines concentration in patients with essential hypertension].
Topics: Adult; Aged; Aldosterone; Angiotensins; Caffeine; Catecholamines; Coffee; Humans; Hypertension; Male | 1999 |
Primary hyperaldosteronism in essential hypertensives: prevalence, biochemical profile, and molecular biology.
Topics: Aldosterone; Blood Pressure; Crossing Over, Genetic; Cytochrome P-450 CYP11B2; Dexamethasone; Female | 2000 |
Difficult-to-control hypertension.
Topics: Adrenal Gland Neoplasms; Aldosterone; Catecholamines; Diagnosis, Differential; Humans; Hypertension; | 2000 |
Severity of hypertension in familial hyperaldosteronism type I: relationship to gender and degree of biochemical disturbance.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Circadian Rhythm; Cytochrome P-45 | 2000 |
Renin-angiotensin-aldosterone system in pregnancy-induced hypertension.
Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Female; Humans; Hypertension; Peptidyl-Dipeptidase A | 2000 |
Different regulation of cardiac and renal corticosteroid receptors in aldosterone-salt treated rats: effect of hypertension and glucocorticoids.
Topics: Adrenalectomy; Age Factors; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blottin | 2000 |
Premature closure or do not get lost in your diagnostic work-up and blame it on the patient.
Topics: Adult; Aldosterone; Angiography; Diagnostic Errors; Diuretics; Female; Humans; Hypertension; Renal A | 2000 |
Reversal of cardiac hypertrophy and fibrosis by S21402, a dual inhibitor of neutral endopeptidase and angiotensin converting enzyme in SHRs.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cardiomeg | 2000 |
Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy.
Topics: Adolescent; Aldosterone; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Binding, Compe | 2000 |
Delayed hypotensive effect of the thromboxane A2/prostaglandin H2 receptor antagonist S-1452 in spontaneously hypertensive rats.
Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Bridged | 2000 |
[Mechanism of primary hypertension].
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Aldosterone; Animals; Corticosterone; Humans; Hydroxyst | 1998 |
Molecular variations in the calcium-sensing receptor in relation to sodium balance and presence of hypertension in blacks and whites.
Topics: Adolescent; Adult; Aldosterone; Black People; Blood Pressure; Blood Pressure Monitoring, Ambulatory; | 2000 |
Genetic variation of the gamma subunit of the epithelial Na+ channel and essential hypertension. Relationship with salt sensitivity.
Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; DNA; DNA Primers; Epithel | 2000 |
[Incidence of primary hyperaldosteronism in hospitalized patients with hypertension].
Topics: Adult; Aldosterone; Female; Hospitalization; Humans; Hyperaldosteronism; Hypertension; Male; Middle | 1999 |
Hypertension. Mutation points to salt recycling pathway.
Topics: Aldosterone; Female; Humans; Hypertension; Kidney; Male; Point Mutation; Pregnancy; Pregnancy Compli | 2000 |
Prevalence of primary aldosteronism among Asian hypertensive patients in Singapore.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; China; Female; Humans; Hyperaldos | 2000 |
[Response of vasoactive substance to blood pressure changes during hemodialysis in uremic patients].
Topics: Aldosterone; Atrial Natriuretic Factor; Blood Volume; Female; Humans; Hypertension; Male; Nitric Oxi | 1999 |
Child abuse in an infant presenting as unexplained acute systemic hypertension.
Topics: Acute Disease; Aldosterone; Antihypertensive Agents; Blood Pressure; Captopril; Child Abuse; Femoral | 2000 |
The aldosterone/renin ratio as a screening test for primary aldosteronism.
Topics: Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 2000 |
[What tests should be conducted for secondary arterial hypertension in hypertensive patients resistant to treatment?].
Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Cohort Studies; Drug Combinations; Follo | 2000 |
Renin inhibition improves pressure natriuresis in essential hypertension.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Imidazoles; Male; Middle | 2000 |
Role of salt in hypertensive left venticular diastolic function.
Topics: Aldosterone; Blood Flow Velocity; Diastole; Echocardiography, Doppler, Color; Heart Ventricles; Huma | 2000 |
Roles of renal dopamine and kallikrein-kinin systems in antihypertensive mechanisms of exercise in rats.
Topics: Aldosterone; Animals; Aromatic-L-Amino-Acid Decarboxylases; Blood Pressure; Blotting, Northern; Body | 2000 |
Circadian rhythms in the renin-angiotensin system and adrenal steroids may contribute to the inverse blood pressure rhythm in hypertensive TGR(mREN-2)27 rats.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Animals, Genetically Modified; Blood Pressure; Circad | 2000 |
Cardiac aldosterone production in genetically hypertensive rats.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardi | 2000 |
Hypertension associated with multiple renal arteries may be renin-dependent.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Female; Furosemide; Humans; Hypertension; Male; Middl | 2000 |
[Role of hypothalamo-hypophyseal-adrenal axis in the pathogenesis of arterial hypertension in patients with prolactinoma of the anterior lobe of the hypophysis].
Topics: Adult; Aldosterone; Bromocriptine; Data Interpretation, Statistical; Dopamine; Dopamine Agonists; Fe | 2000 |
Dexamethasone-suppressible hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Dexamethasone; Female; Genotype; Glucocor | 2000 |
Nephrocalcinosis and renal cysts associated with apparent mineralocorticoid excess syndrome.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adolescent; Aldosterone; Alkalosis; Female; Humans; Hydroxyst | 2000 |
The urinary levels of catecholamines, aldosterone and cortisol in hypertensive East Africans: a pilot study.
Topics: Adolescent; Aldosterone; Catecholamines; Female; Humans; Hydrocortisone; Hypertension; Kenya; Male; | 2000 |
Prenatal programming of adult hypertension in the rat.
Topics: Aging; Aldosterone; Animals; Apoptosis; Blood Pressure; Creatine; Dietary Proteins; Female; Fetal Gr | 2001 |
[The autonomic nervous system and hypertension: quid novi?].
Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Humans; Hypertension | 2000 |
Serum aldosterone changes during hyperinsulinemia are correlated to body mass index and insulin sensitivity in patients with essential hypertension.
Topics: Aldosterone; Biomarkers; Blood Glucose; Blood Pressure; Body Mass Index; Calcium; Disease Progressio | 2001 |
The renin-aldosterone system during normal and hypertensive pregnancy.
Topics: Adult; Aldosterone; Birth Weight; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy | 2001 |
Two sporadic cases of Liddle's syndrome caused by De novo ENaC mutations.
Topics: Adult; Aldosterone; Epithelium; Female; Humans; Hypertension; Hypokalemia; Male; Mutation, Missense; | 2001 |
Approach to the patient with hypertension, unexplained hypokalemia, and metabolic alkalosis.
Topics: Adenoma; Adrenalectomy; Aldosterone; Alkalosis; Antihypertensive Agents; Diagnosis, Differential; Hu | 2001 |
Antifibrotic effects of N-acetyl-seryl-aspartyl-Lysyl-proline on the heart and kidney in aldosterone-salt hypertensive rats.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cell Division; Colla | 2001 |
A mutation in the cofactor-binding domain of 11beta-hydroxysteroid dehydrogenase type 2 associated with mineralocorticoid hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Amino Acid Sequence; Binding Sites; Cell Line; C | 2001 |
Arterial pressure, left ventricular mass, and aldosterone in essential hypertension.
Topics: Adult; Aldosterone; Black People; Blood Pressure; Body Mass Index; Canada; Circadian Rhythm; Electro | 2001 |
Effect of sympathetic and plasma renin activity on hemodialysis hypertension.
Topics: Adult; Aldosterone; Chromatography, High Pressure Liquid; Epinephrine; Female; Humans; Hypertension; | 2001 |
Screening for primary aldosteronism without discontinuing hypertensive medications: plasma aldosterone-renin ratio.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyper | 2001 |
Hormone replacement therapy increases plasma level of angiotensin II in postmenopausal hypertensive women.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Bradykinin; Female; Hormone Replacement Therapy; Humans; | 2001 |
The role of nitric oxide and the renin-angiotensin system in salt-restricted Dahl rats.
Topics: Aldosterone; Animals; Blood Pressure; Diet, Sodium-Restricted; Down-Regulation; Glucuronidase; Hyper | 2001 |
Cautions over the current epidemic of primary aldosteronism.
Topics: Aldosterone; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Renin | 2001 |
Twenty-Four hour blood pressure profile in subjects with different subtypes of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Pressure; Blood Pressure Determination; | 2001 |
Aldosterone to renin ratio as a determinant of exercise blood pressure response in hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Determination; Exercise; Exercise Test; Female; H | 2001 |
Salt sensitivity in genetically hypertensive rats of the Lyon strain.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Press | 2001 |
Effects of high sodium intake on cardiovascular aldosterone synthesis in stroke-prone spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Cardiovascular System; Diet; Genetic Predisposition to Disease; Hypertension; | 2001 |
[Excess of mineralocorticoids in essential hypertension: clinical-diagnostic approach].
Topics: Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potas | 2000 |
Paraneoplastic hyperaldosteronism associated with non-Hodgkin's lymphoma.
Topics: Aldosterone; Cytochrome P-450 CYP11B2; Fatal Outcome; Humans; Hyperaldosteronism; Hypertension; Lymp | 2001 |
Diagnosis of Liddle syndrome by genetic analysis of beta and gamma subunits of epithelial sodium channel--a report of five affected family members.
Topics: Adolescent; Adult; Aged; Aldosterone; Base Sequence; Child; DNA; Epithelial Sodium Channels; Female; | 2001 |
ET(A) receptor antagonist prevents blood pressure elevation and vascular remodeling in aldosterone-infused rats.
Topics: Aldosterone; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Body Weight; Dansyl Compounds; | 2001 |
Insulin, renin-aldosterone system and blood pressure in obese people.
Topics: Adult; Aldosterone; Blood Pressure; Cross-Sectional Studies; Female; Humans; Hyperinsulinism; Hypert | 2001 |
Chronic treatment with amlodipine modulates adrenocortical angiotensin II receptors in spontaneously hypertensive rats.
Topics: Adrenal Cortex; Aldosterone; Amlodipine; Animals; Antihypertensive Agents; Hypertension; Male; Rats; | 2001 |
Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Antioxidants; Bl | 2001 |
Insulin sensitivity and sodium excretion in normotensive offspring and hypertensive patients.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Insulin; Insulin Resistance; Male; Norepinephrine; | 2001 |
A family with liddle's syndrome caused by a mutation in the beta subunit of the epithelial sodium channel.
Topics: Aldosterone; Alkalosis; Base Sequence; Blood Gas Analysis; Calcium Channel Blockers; Diagnosis, Diff | 2001 |
Cautions over idiopathic aldosteronism.
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension | 2001 |
Prevalence of primary aldosteronism in unselected hypertensive populations: screening and definitive diagnosis.
Topics: Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Pota | 2001 |
Mineralocorticoids upregulate arterial contraction to epidermal growth factor.
Topics: Aldosterone; Animals; Aorta, Thoracic; Blood Pressure; Desoxycorticosterone; Dose-Response Relations | 2001 |
Primary aldosteronism: factors associated with normalization of blood pressure after surgery.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aged, 80 and over; Aldosterone; Analys | 2001 |
Lack of association between Gly460Trp polymorphism of alpha-adducin gene and salt sensitivity of blood pressure in Polish hypertensives.
Topics: Adult; Aldosterone; Amino Acid Sequence; Blood Pressure; Calmodulin-Binding Proteins; Diet, Sodium-R | 2001 |
Screening for primary aldosteronism--normal ranges for aldosterone and renin in three South African population groups.
Topics: Aldosterone; Ethnicity; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Prevale | 2001 |
Adrenal response to angiotensin II in black hypertension: lack of sexual dimorphism.
Topics: Adrenal Glands; Adult; Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Black People; Fema | 2001 |
Hemodynamic and metabolic profile in offspring of malignant hypertensive parents.
Topics: Adolescent; Adult; Aldosterone; Blood Glucose; Blood Pressure; Cholesterol; Diastole; Family Health; | 2001 |
A new role for progesterone: an agonist for mineralocorticoid receptor activation and pregnancy-related hypertension.
Topics: Aldosterone; Codon, Nonsense; Female; Heterozygote; Humans; Hypertension; Pregnancy; Pregnancy Compl | 2001 |
-344C/T polymorphism of CYP11B2 gene in Italian patients with idiopathic low renin hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cytochrome P-450 CYP11B2; Gene Fre | 2001 |
Enrasentan improves survival, limits left ventricular remodeling, and preserves myocardial performance in hypertensive cardiac hypertrophy and dysfunction.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Carboxylic Acids; Endothelin Recept | 2001 |
Adverse cardiac effects of salt with fludrocortisone in hypertension.
Topics: Aldosterone; Anti-Inflammatory Agents; Blood Pressure; Echocardiography; Electrocardiography; Fludro | 2001 |
Role of renin-angiotensin-aldosterone system in salt-sensitive hypertension induced by sensory denervation.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Capsaicin; Denervation; Female; Hypertension; Min | 2001 |
Insulin sensitivity with respect to glucose metabolism in hypertension-prone men did not predict the blood pressure increase in 5 years.
Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Body Mass Index; Family Health; Follow-Up Studies | 2001 |
Role of angiotensin converting enzyme genotype in sodium sensitivity in older hypertensives.
Topics: Aged; Aging; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Genotype; Humans; Hyperte | 2001 |
Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Dose-Response Relationship, Drug; Family Health; Germany; Hemody | 2002 |
[Study on the relation between hypertensive left ventricular hypertrophy in very old people with neurohormonal factors and ventricular arrhythmias].
Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Arrhythmias, Cardiac; Female; Humans; Hyperten | 2000 |
Left ventricular structure and diastolic function in subjects with two hypertensive parents.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Case-Control Studies; Catecholamines | 2001 |
Normokalemic hyperaldosteronism in patients with resistant hypertension.
Topics: Adult; Aged; Aldosterone; Analysis of Variance; Antihypertensive Agents; Creatinine; Female; Humans; | 2002 |
Primary aldosteronism: the most frequent form of secondary hypertension?
Topics: Aldosterone; Antihypertensive Agents; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Mineral | 2002 |
Effects of long-term enalapril and losartan therapy of hypertension on cardiovascular aldosterone.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit | 2001 |
Salt-sensitive hypertension resulting from nitric oxide synthase inhibition is associated with loss of regulation of angiotensin II in the rat.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Enzyme Inhibit | 2002 |
Test and teach. Surgically correctable hypertension. Conn's syndrome and spironolactone bodies.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertens | 2001 |
Mutations in aldosterone synthase gene of Milan hypertensive rats: phenotypic consequences.
Topics: 18-Hydroxycorticosterone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldo | 2002 |
Role of aldosterone in the pathogenesis of hypertension.
Topics: Aldosterone; Blood Pressure; Cytochrome P-450 CYP11B2; Exercise; Humans; Hypertension; Quantitative | 2002 |
Hypertension due to a giant aldosterone-secreting adenoma.
Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Female; Humans; Hypertension; Middle Aged; Tomograph | 2001 |
Upregulation of arterial serotonin 1B and 2B receptors in deoxycorticosterone acetate-salt hypertension.
Topics: Aldosterone; Animals; Desoxycorticosterone; Gene Expression; Hypertension; Male; Mineralocorticoids; | 2002 |
Effects of losartan and benazepril on abnormal circadian blood pressure rhythm and target organ damage in SHRSP.
Topics: Aldosterone; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Cardiomegaly; Circadian | 2002 |
Is primary aldosteronism underdiagnosed in clinical practice?
Topics: Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Diagnosis, Differential; Humans; Hyperaldostero | 2001 |
Dysregulation of angiotensin II synthesis is associated with salt sensitivity in the spontaneous hypertensive rat.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting | 2002 |
[Hypertension: once primary, always primary?].
Topics: Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Female; Humans; Hyperaldosteron | 2002 |
Primary aldosteronism in normokalemic patients with adrenal incidentalomas.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Fe | 2002 |
Influence of plasma aldosterone on left ventricular geometry and diastolic function in treated essential hypertension.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Diastole; Echocardiography; Female; Heart Vent | 2002 |
Ratio of serum aldosterone to plasma renin concentration in essential hypertension and primary aldosteronism.
Topics: Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Prosp | 2002 |
Combination of non-hypotensive doses of valsartan and enalapril improves survival of spontaneously hypertensive rats with endothelial dysfunction.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Press | 2000 |
The role of spironolactone in the treatment of patients with refractory hypertension.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Mid | 2002 |
Stress-induced renal alterations in normotensives offspring of hypertensives and in hypertensives.
Topics: Aldosterone; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Renin; Sodium; | 2002 |
Aldosterone is produced from ventricles in patients with essential hypertension.
Topics: Aldosterone; Analysis of Variance; Atrial Natriuretic Factor; Blood Pressure; Female; Heart Ventricl | 2002 |
Unilateral adrenal hyperplasia causing primary aldosteronism: limitations of I-131 norcholesterol scanning.
Topics: Adosterol; Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; Iodin | 2002 |
Aldosterone acts on the kidney, not the brain, to cause mineralocorticoid hypertension in sheep.
Topics: Aldosterone; Animals; Blood; Blood Pressure; Body Fluids; Brain; Electrolytes; Female; Hormones; Hyp | 2002 |
Comparison of circulating and local adipose tissue renin-angiotensin system in normotensive and hypertensive obese subjects.
Topics: Adipose Tissue; Adult; Aldosterone; Angiotensinogen; Blood; Female; Humans; Hypertension; Male; Midd | 2002 |
Effects of hormone replacement therapy on left ventricular hypertrophy and growth-promoting factors in hypertensive postmenopausal women.
Topics: Aldosterone; Echocardiography; Estrogen Replacement Therapy; Female; Growth Substances; Humans; Hype | 2002 |
Aldosterone excess and essential hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension | 2002 |
Renin-producing serous cystoadenocarcinoma of the ovary: a case report.
Topics: Aldosterone; Cystadenocarcinoma, Serous; Diagnosis, Differential; Female; Humans; Hyperaldosteronism | 2002 |
Excess aldosterone is associated with alterations of myocardial texture in primary aldosteronism.
Topics: Adult; Aged; Aldosterone; Echocardiography, Doppler; Female; Heart; Heart Ventricles; Humans; Hypera | 2002 |
Aldosterone breakthrough during angiotensin II receptor antagonist therapy in stroke-prone spontaneously hypertensive rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; | 2002 |
[Effect of chronic beta-receptor blockade in blood pressure and renin and aldosterone secretion in essential hypertension].
Topics: Adrenergic beta-Antagonists; Aldosterone; Blood Pressure; Humans; Hypertension; Renin | 1975 |
Long term treatment of moderate hypertension with penbutolol (Hoe 893d). I. Effects on blood pressure, pulse rate, catecholamines in blood and urine, plasma renin activity and urinary aldosterone under basal conditions and following exercise.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Cyclopentanes | 1975 |
Renin and age as determinants of a predominantly betablocker-based antihypertensive drug program.
Topics: Adrenergic beta-Antagonists; Adult; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Blo | 1976 |
Labetalol (AH5158), a competitive alpha- and beta-receptor blocking drug, in the management of hypertension.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Cloni | 1976 |
Clonidine and the vasodilating beta blocker antihypertensive drug interaction.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Clonidine; Drug Interactions; Femal | 1977 |
Mineralocorticoid radioreceptor assay: application to adrenal-regeneration hypertension.
Topics: Adrenal Glands; Aldosterone; Animals; Cytosol; Hydrogen-Ion Concentration; Hypertension; Mineralocor | 1977 |
[Recurrent aldosteronism and arterial hypertension following adrenalectomy. One clinical case (author's transl)].
Topics: Adrenal Glands; Adrenalectomy; Adrenergic beta-Antagonists; Adult; Aldosterone; Humans; Hyperaldoste | 1978 |
Need for beta-blockade in hypertension reduced with long-term minoxidil.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Female; Follow-Up Studies; Humans; Hypertension; Ma | 1978 |
Symposium: Renin-angiotensin-aldosterone system and hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Congresses as Topic; Germany, West; Humans; Hypertension; Reni | 1978 |
[Hormone and mediator content in the blood of the adrenals and in the peripheral blood in hypertension].
Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adult | 1979 |
[Behavior of cardiac output, plasma volume, plasma renin activity and aldosterone secretion in patients with essential hypertension treated with beta-blocking agents and diuretics].
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Volume; Cardiac Output; Chlorthalidone; Diure | 1979 |
Is low-renin hypertension a stage in the development of essential hypertension or a diagnostic entity?
Topics: Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Blood Specimen Collection; Female; Humans; Hy | 1975 |
Severe arterial hypertension caused by chronical abuse of a topical mineralocorticoid.
Topics: Adult; Aldosterone; Clonidine; Drug Combinations; Drug Therapy, Combination; Female; Fluprednisolone | 1975 |
Rectal potential difference in essential hypertension.
Topics: Action Potentials; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Rectum; Renin | 1976 |
Dexamethasone-responsive hypertension in young women with suppressed renin and aldosterone.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure; Body Weight; Dexamethasone; Female; | 1978 |
Active and total renin in physiological and pathophysiological conditions [proceedings].
Topics: Age Factors; Aldosterone; Humans; Hypertension; Renin; Sodium | 1977 |
A renal abnormality as a possible cause of "essential" hypertension.
Topics: Adult; Aldosterone; Animals; Blood Pressure; Cardiac Output; Catecholamines; Female; Glomerular Filt | 1979 |
Influence of beta blockade on the renin-angiotensin-aldosterone system [proceedings].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Metoprolol; Propanolamines; Propranolol; Renin | 1979 |
Idiopathic aldosteronism: a diagnostic artifact?
Topics: Aldosterone; Angiotensin II; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Reni | 1979 |
Evidence for a new mineralocorticoid in patients with low-renin essential hypertension.
Topics: Adrenalectomy; Aldosterone; Animals; Biological Assay; Chromatography, Gas; Corticosterone; Cortison | 1975 |
The Distinguished Lecture. Is hypertension essential?
Topics: Aldosterone; Aminoglutethimide; Angiotensin II; Animals; Dehydroepiandrosterone; Humans; Hypertensio | 1975 |
Interaction of 16beta-hydroxydehydroepiandrosterone with renal mineralocorticoid receptors.
Topics: Aldosterone; Animals; Binding, Competitive; Dehydroepiandrosterone; Hypertension; Kidney; Male; Mine | 1977 |
Pathogenic significance of adrenocortical hormones in essential hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Aldosterone; Cortodoxone; Dehydroepiandrost | 1977 |
Hypertension, hypokalemia, hyporeninemia and severe target organ damage.
Topics: Aldosterone; Blood Pressure; Cardiomegaly; Female; Humans; Hyperaldosteronism; Hypertension; Hypokal | 1976 |
[Comparative study of plasma levels of renin and aldosterone activity in essential arterial hypertension in relation to duration of the disease and the presence of complications].
Topics: Acute Disease; Adolescent; Adult; Aldosterone; Cardiomegaly; Chronic Disease; Female; Humans; Hypert | 1977 |
A case of ectopic renin-secreting orbital hemangiopericytoma associated with juvenile hypertension and hypokalemia.
Topics: Adolescent; Aldosterone; Brain; Brain Neoplasms; Exophthalmos; Female; Hemangiopericytoma; Humans; H | 1979 |
Plasma renin activity and in vitro synthesis of aldosterone by the adrenal glands of rats with spontaneous, renal, or pinealectomy-induced hypertension.
Topics: Adenosine Monophosphate; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pr | 1975 |
Dynamic aldosterone and 18-hydroxydeoxycorticosterone studies in labile and stable benign essential hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adrenocorticotropic Hormone; Aldosterone; Carrier Proteins; Circadia | 1975 |
Enhanced aldosterone response to angiotensin II in human hypertension.
Topics: Adrenal Cortex; Adrenal Glands; Adult; Aldosterone; Analysis of Variance; Angiotensin II; Female; Hu | 1976 |
The regulation of plasma 18-hydroxy 11-deoxycorticosterone in man.
Topics: 18-Hydroxydesoxycorticosterone; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Des | 1976 |
Unusual low plasma renin hypertension in a child.
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Alkalosis; | 1976 |
[State of the renal-pressor units of arterial pressure regulation in primary arterial hypertension in children and adolescents].
Topics: Adolescent; Adrenal Cortex; Adrenal Glands; Aldosterone; Child; Endopeptidases; Humans; Hypertension | 1976 |
Aldosterone receptors and the evaluation of plasma mineralocorticoid activity in normal and hypertensive states.
Topics: Aldosterone; Androstenediols; Animals; Binding, Competitive; Corticosterone; Depression, Chemical; D | 1976 |
The role of ACTH in the episodic release of aldosterone in patients with idiopathic adrenal hyperplasia, hypertension, and hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Depressi | 1976 |
Plasma deoxycorticosterone and aldosterone in essential hypertension.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Desoxycorticosterone; Female; Humans; Hypertension; | 1976 |
The mechanism of low-renin hypertension: aldosterone response to sodium restriction and upright posture, angiotensin II, ACTH and potassium in patients with hypertension.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensin II; Diet; Female; Humans; Hydroco | 1976 |
Effects of ACTH on plasma levels of adrenal steroids in essential hypertension.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure; Corticoste | 1976 |
[Changes of the renin-angiotensin-aldosterone system under contraceptive steroids. Contribution to the etiology of hypertension under hormonal contraceptives].
Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Endopeptid | 1976 |
Evidence for an unidentified ACTH-induced steroid hormone causing hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldoste | 1976 |
[State of the neurohumoral regulatory system in circulatory insufficiency].
Topics: 17-Ketosteroids; Adult; Aged; Aldosterone; Angiotensinogen; Coronary Disease; Cortisone; Endopeptida | 1976 |
Endocrine and cardiovascular consequences of angiotensin converting enzyme inhibition.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Dose-Response Relationship, D | 1977 |
Response of several adrenal steroids to ACTH stimulation in essential hypertension.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Corticoste | 1977 |
Unexpected pressor responses to propranolol in essential hypertension. An interaction between renin, aldosterone and sympathetic activity.
Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Body Weight; Depression, Chemical; Female; Heart Ra | 1976 |
Blockade of renin or angiotensin for understanding human hypertension: a comparison of propranolol, saralasin and converting enzyme blockade.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Volume; | 1977 |
The role of the adrenal cortex in human essential hypertension: keynote address.
Topics: 18-Hydroxydesoxycorticosterone; Adolescent; Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Horm | 1977 |
[Do aldosterone and other mineralocorticoids play a role in the pathogenesis of essential hypertension?].
Topics: 17-alpha-Hydroxypregnenolone; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Proteins; Cir | 1977 |
Plasma concentration of aldosterone, 18-hydroxy-deoxycorticosterone and cortisol in adrenal veins of patients with low-renin hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropi | 1977 |
Effects of ACTH and posture on aldosterone metabolism in essential hypertension.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Po | 1977 |
[2 models of indomethacin-induced arterial hypertension in rats in chronic experiments].
Topics: Aldosterone; Angiotensins; Animals; Cyclic AMP; Disease Models, Animal; Hypertension; Indomethacin; | 1977 |
[Primary hyperaldosteronism with paroxysmal arterial hypertension. Apropos of 2 operated cases].
Topics: Adrenal Glands; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Mi | 1978 |
Plasma levels of 18-hydroxy-11-deoxycorticosterone in essential hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Cir | 1978 |
Mineralocorticoids, salt balance and blood pressure after prolonged ACTH administration in juvenile hypertension.
Topics: Adolescent; Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Body Weight; Child; Humans; Hy | 1978 |
[Effect of varied sodium intake on the excretion of desoxycorticosterone, cortisol and aldosterone as well as the ACTH stimulation of those corticoids].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Cortisone; Desoxycorticosterone; | 1978 |
The adrenal receptor for angiotensin II is altered in essential hypertension.
Topics: Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; | 1979 |
Effect of angiotensin converting enzyme inhibition on blood pressure, plasma renin activity and plasma aldosterone in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Female; Humans; Hypert | 1978 |
Effect of posture on the plasma concentrations of aldosterone in hypertension and primary hyperaldosteronism.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Circadian Rhythm; Desoxycorticost | 1979 |
Adrenocortical function, electrolyte metabolism, and blood pressure during prolonged adrenocorticotropin infusion in juvenile hypertension.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure | 1979 |
Orally active angiotensin-converting enzyme inhibitor (SO 14,225) as a treatment for essential hypertension.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Female; Humans; Hypert | 1979 |
Reduced response of plasma aldosterone to acute ACTH stimulation during long-term treatment with spironolactone in essential hypertension.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure; Humans; Hydrochlorothiazide; Hydroc | 1979 |
Plasma aldosterone response to ACTH in primary aldosteronism and in patients with low renin hypertension.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldost | 1978 |
The biologic significance of the aldosterone concentration in saliva.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Child; Child, Preschool; Dexamethasone; | 1979 |
A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Aldosterone; Child; Cortisone; Humans; Hydro | 1979 |
Adrenocortical steroid hormones in production of hypertension in sheep.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure; Cardiac | 1979 |
[A study on the mechanism of aldosterone secretion in low-renin essential hypertension (author's transl)].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Electrolytes; Female; Furosemide; H | 1979 |
Effects of chronic treatment with captopril (SQ 14,225), an orally active inhibitor of angiotensin I-converting enzyme, in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Heart; Hy | 1979 |
Humoral effects of the oral converting-enzyme inhibitor SQ 14,225 in hypertensive patients in supine and tilted position.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Epinephrine; Human | 1979 |
A novel orally active converting-enzyme inhibitor YS 980: effects on blood pressure in spontaneously hypertensive rats.
Topics: 3-Mercaptopropionic Acid; Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Anim | 1979 |
Aldosterone and in vivo mineralocorticoid activity in normotensive and hypertensive man.
Topics: Action Potentials; Adrenal Cortex Diseases; Aldosterone; Female; Humans; Hyperaldosteronism; Hyperte | 1979 |
Urinary free 18-hydroxy-11-desoxycorticosterone excretion in normal and hypertensive patients.
Topics: 18-Hydroxydesoxycorticosterone; Adrenocorticotropic Hormone; Aldosterone; Desoxycorticosterone; Diet | 1978 |
Rectal potential difference in the diagnosis of aldosterone excess.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Desoxycorticosterone; Diet; Electrodes; Female; | 1975 |
The effect of clonidine and penbutolol, respectively on catecholamines in blood and urine, plasma renin activity and urinary aldosterone in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Butylamines; Catecholamines; Clonidine; Cyclopentan | 1975 |
Effects of dietary potassium and race on urinary excretion of kallikrein and aldosterone in man.
Topics: Adult; Aldosterone; Diet; Female; Humans; Hypertension; Kallikreins; Male; Middle Aged; Potassium; R | 1978 |
[A precise bioassay for in vivo mineralocorticoid activity in man: relation to plasma aldosterone in normal subjects, essential hypertension, hyperaldosteronism and adrenocortical insufficiency (author transl)].
Topics: Adrenal Cortex Diseases; Aldosterone; Circadian Rhythm; Humans; Hyperaldosteronism; Hypertension; In | 1977 |
Renin and aldosterone measurements in the diagnosis and management of hypertension. I. Renin and aldosterone measurements in the etiological diagnosis of hypertension.
Topics: Adolescent; Adult; Aldosterone; Child; Child, Preschool; Female; Humans; Hypertension; Hypertension, | 1977 |
Renin and aldosterone measurements in the diagnosis and management of hypertension. II. Renin and aldosterone measurements as guide of drug therapy in hypertension.
Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1977 |
Clinical use of plasma renin assays.
Topics: Adolescent; Adrenal Gland Diseases; Adult; Aged; Aldosterone; Bartter Syndrome; Female; Humans; Hype | 1978 |
Plasma aldosterone in essential hypertension.
Topics: Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Sodium | 1978 |
Renin, aldosterone, sodium and potassium in essential hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Humans; Hypertension; Male; Middle Aged; Potassium; Renin; Sod | 1978 |
A physiological basis for the treatment of essential hypertension.
Topics: Aldosterone; Clonidine; Diuretics; Humans; Hypertension; Propranolol; Renin; Sodium | 1978 |
Acid-activated renin responses to hydrochlorothiazide, propranol and indomethacin.
Topics: Adult; Aldosterone; Blood Pressure; Enzyme Activation; Humans; Hydrochlorothiazide; Hypertension; In | 1978 |
The natural history of hypertension in turkeys.
Topics: Aging; Aldosterone; Animals; Blood Pressure; Creatinine; Hypertension; Lipids; Potassium; Renin; Sod | 1978 |
Evidence for an unidentified, adrenocorticotrophic hormone-dependent mineralocorticoid maintaining hypertension in young women with hypoaldosteronism.
Topics: Adult; Aldosterone; Body Weight; Dexamethasone; Female; Humans; Hypertension; Hypokalemia; Renin | 1978 |
Effects of labetalol on systemic and pulmonary haemodynamics at rest and during exercise in hypertensive patients.
Topics: Adult; Aldosterone; Ethanolamines; Female; Hemodynamics; Humans; Hypertension; Labetalol; Male; Midd | 1978 |
Renin--angiotensin system in mild essential hypertension. The functional significance of angiotensin II in untreated and thiazide-treated hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Benzothiadiazines; Blood Pressure; Diuretics; Female; Humans; Hy | 1978 |
The role of intrarenal vasoactive substances in the pathogenesis of essential hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Female; Furosemide; H | 1978 |
Noradrenaline secretion by the human kidney.
Topics: Aging; Aldosterone; Blood Pressure; Humans; Hypertension; Kidney; Norepinephrine; Propranolol; Renin | 1978 |
Haemodynamic and endocrinological profile of essential hypertension.
Topics: Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Blood Volume; Cardiac Output; Extracellular S | 1978 |
Effect of sodium loading on the renin-aldosterone system in essential hypertension.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Male; Natriuresis; Renin; Sodium; Sodium Chloride | 1979 |
Pathophysiological mechanisms of the antihypertensive effect of a cardioselective beta-adrenoceptor blocking drug (metoprolol).
Topics: Aldosterone; Cardiac Output; Hemodynamics; Humans; Hypertension; Kidney; Male; Metoprolol; Middle Ag | 1979 |
Renin angiotensin system and sympathetic nerve activity in mild essential hypertension. The functional significance of angiotensin II in untreated and thiazide treated hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle | 1979 |
Measurement of the end-organ responses to aldosterone in man: diversity of response and its possible biological significance.
Topics: Action Potentials; Adult; Aged; Aldosterone; Electrophysiology; Female; Humans; Hypertension; Kidney | 1979 |
Intrinsic defect of aldosterone synthesis in dexamethasone-responsive hypertension with suppressed renin and aldosterone.
Topics: Adult; Aldosterone; Dexamethasone; Female; Humans; Hydrocortisone; Hypertension; Renin | 1979 |
"Outpatient hyperkalemia" syndrome in renal and hypertensive patients with suppressed aldosterone production.
Topics: Adult; Aged; Aldosterone; Diet, Sodium-Restricted; Female; Humans; Hyperkalemia; Hypertension; Kidne | 1979 |
[SAR1, ALA8]-Angiotensin II (saralasin): a symposium. Introduction.
Topics: Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Hypertension, Renal; Renin; Saralasin | 1979 |
[Mineralocorticoid hypertension: clinical and laboratory aspects with emphasis on selective percutaneous venography associated with aldosterone determination in the adrenal vein].
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Middle Aged; Mineralocorticoids; Phlebography; Pot | 1977 |
[17 alpha-hydroxylase deficiency].
Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Female; Humans; Hypertension; Hypogonadism; Male; Ster | 1977 |
[Antihypertensive effect of carteolol, a beta-receptor blockader, in essential hypertension and its action on the renin-aldosterone system].
Topics: Adolescent; Adult; Aged; Aldosterone; Antihypertensive Agents; Female; Humans; Hypertension; Levobun | 1977 |
Plasma renin, plasma aldosterone and exchangeable sodium in normotensive and hypertensive kidney transplant recipients with and without transplant renal artery stenosis.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Kidney Transplantation; Male; Middle Aged; Natriur | 1977 |
Studies of renin-aldosterone axis in stable normotensive and hypertensive renal allograft recipients.
Topics: Adult; Aldosterone; Creatinine; Female; Humans; Hypertension; Kidney Transplantation; Male; Postoper | 1978 |
Role of the renin-angiotensin system in post-transplantation hypertension in patients with multiple kidneys.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet; Female; Humans; Hypertension; | 1978 |
Late hypertension following renal allotransplantation.
Topics: Adolescent; Adult; Aldosterone; Female; Follow-Up Studies; Humans; Hypertension; Hypertension, Renal | 1979 |
Prolonged pseudoaldosteronism induced by glycyrrhizin.
Topics: Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Glycyrrhetinic Acid; Glycyrrhiza | 1979 |
Effects of an angiotensin II antagonist; [sarcosine 1, isoleucine 8] angiotensin II, on blood pressure, plasma renin activity and plasma aldosterone concentration in hypertensive and normotensive subjects taking oral contraceptives.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Angiotensin II; Blood Pressure; Contrac | 1979 |
[Biochemical diagnosis of hypertension in adrenal gland diseases].
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Catecholamines; Corticosterone; Desoxycorticosterone; H | 1979 |
Central and renal circulation, renin and aldosterone in plasma during prazosin treatment in essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Chemical Analysis; Blood Circulation; Cardiac Output; Female; Hemody | 1979 |
[Effects of minoxidil on blood pressure and plasma volume in refractory hypertension (author's transl)].
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Dihydralazine; Female; Humans; Hypertension; Male; M | 1979 |
Are idiopathic hyperaldosteronism and low-renin hypertension variants of essential hypertension?
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Angiotensin II; Blood Pressure; | 1979 |
Captopril in hypertension with renal artery stenosis and in intractable hypertension; acute and chronic changes in circulating concentrations of renin, angiotensins I and II and aldosterone, and in body composition.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Blood Pressure; Captopr | 1979 |
Urinary kallikrein in normotensive subjects and in patients with essential hypertension.
Topics: Adult; Aldosterone; Creatinine; Furosemide; Humans; Hypertension; Kallikreins; Male; Potassium; Reni | 1979 |
Sodium excretion and blood pressure in essential hypertensive patients during the early phase of hospital admission.
Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Cardiac Output; Female; Hospitalization; Human | 1979 |
Haemodynamics during long-term thiazide treatment in essential hypertension: differences between responders and non-responders.
Topics: Adult; Aldosterone; Blood Pressure; Cardiac Output; Heart Rate; Humans; Hydrochlorothiazide; Hyperte | 1979 |
The evidence that salt is an important aetiological agent, if not the cause, of hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoids; Renin; Risk; Sodium; Sodi | 1979 |
Pathophysiological studies on hypertension induced in rats by kidney extract and salt.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood | 1979 |
The role of renal prostaglandin E and kallikrein in pathogenesis of essential hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Femal | 1979 |
[Effects of a single dose of captopril on blood pressure and the renin-angiotensin-aldosterone system in normal subjects and hypertensive patients with various etiologies (author's transl)].
Topics: Adult; Aldosterone; Angiotensin I; Angiotensins; Blood Pressure; Captopril; Humans; Hypertension; Ma | 1979 |
The response of plasma renin activity by oral calcium loading in normal subjects and hypertensive and diabetic patients.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin II; Calcium; Diabetes Complications; Diabetes | 1979 |
Evaluation of patients for secondary hypertension.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Cushing Syndrome; Female; Humans; Hyp | 1979 |
[Reliability and diagnostic use of the furosemide test in the study of the renin-angiotensin-aldosterone system].
Topics: Adolescent; Adult; Aldosterone; Cushing Syndrome; Electrolytes; Female; Furosemide; Humans; Hyperten | 1978 |
[The renin-angiotensin-aldosterone system in arterial hypertension].
Topics: Aldosterone; Angiotensins; Animals; Captopril; Dogs; Humans; Hypertension; Hypertension, Renovascula | 1979 |
Is low urinary prostaglandin concentration a stage in the development of essential hypertension?
Topics: Adult; Aldosterone; Humans; Hypertension; Kidney; Kidney Medulla; Middle Aged; Prostaglandins; Prost | 1979 |
An association between the renin angiotensin system, blood pressure and potassium intake.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure; Humans; Hypertension; Potassium | 1980 |
[Short-term effects of a treatment with methoprolol (a selective beta 1-blocking agent) in essential hypertension. Changes of haemodynamics, renin, aldosterone, sodium and potassium balance (author's transl)].
Topics: Adult; Aldosterone; Drug Evaluation; Female; Hemodynamics; Humans; Hypertension; Male; Metoprolol; M | 1979 |
[Temporal aspects of the function of the renin-angiotensin-aldosterone system. Contribution to the methodological standardization of explorative test (author's transl)].
Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Diet, Sodium-Restricted; Female; Furosemide; Human | 1979 |
[Effect of potassium canrenoate on arterial pressure, plasma renin activity and urinary aldosterone in essential hypertension].
Topics: Adolescent; Adult; Aldosterone; Canrenoic Acid; Female; Humans; Hypertension; Male; Middle Aged; Pre | 1978 |
[Hemodynamic, humoral and renal effects of the acute administration of nifedipine in hypertensive patients].
Topics: Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Creatinine; Electrolytes; Female; Heart Ra | 1979 |
Diurnal 18-hydroxy-11-deoxycorticosterone pattern in human stable hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adolescent; Adult; Aldosterone; Circadian Rhythm; Cushing Syndrome; | 1978 |
Experimental toxemia of pregnancy in the monkey, with a preliminary report on renin and aldosterone.
Topics: Aldosterone; Animals; Aorta; Constriction; Disease Models, Animal; Female; Haplorhini; Hypertension; | 1977 |
Value of the spironolactone test in the diagnosis of primary hyperaldosteronism.
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potassium; | 1979 |
Cardiovascular and endocrine profile of adrenergic neurone blockade in normal and hypertensive man.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Volume; Body Weight; Debrisoquin; Female; Hemodynami | 1979 |
The biological significance of reduced metabolites of aldosterone.
Topics: Aldosterone; Biotransformation; Humans; Hypertension; Renin | 1979 |
Evidence for heterogeneity of mineralocorticoids in urine of patients with low renin essential hypertension.
Topics: Aldosterone; Corticosterone; Humans; Hypertension; Mineralocorticoids; Progesterone; Reference Value | 1979 |
Role of the renin-angiotensin-aldosterone system in hypertensive children with coarctation of the aorta.
Topics: Adolescent; Adult; Aldosterone; Angiotensins; Aortic Coarctation; Body Fluids; Cardiac Catheterizati | 1979 |
Enhanced adrenal responsiveness to angiotensin II in patients with low renin essential hypertension.
Topics: Adolescent; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Dose-Response Relationship, Drug; Hu | 1979 |
Effect of adrenal suppression with dexamethasone in essential hypertension.
Topics: Adrenal Glands; Adult; Aldosterone; Blood Pressure; Dexamethasone; Humans; Hydrocortisone; Hypertens | 1979 |
Essential role of mean circulatory filling pressure in salt-induced hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Blood Volume; Cardiac Output; Dogs; Heart Rate; Hydrocortisone | 1979 |
Aldosterone, deoxycorticosterone, corticosterone, and prolactin changes during the lifespan of chronically and spontaneously hypertensive rats.
Topics: Aging; Aldosterone; Animals; Blood Pressure; Corticosterone; Desoxycorticosterone; Female; Hypertens | 1979 |
Chronobiology of blood pressure.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Circadian Rhythm; Desoxycorticosterone; | 1979 |
[Behavior of the renin-angiotensin-aldosterone system and of electrolyte and water excretion in male and female spontaneously hypertensive and normotensive rats under the influence of a saluretic].
Topics: Aldosterone; Angiotensin II; Animals; Azoles; Circadian Rhythm; Corticosterone; Diuretics; Electroly | 1979 |
Rapid blood pressure control with minoxidil: acute and chronic effects on blood pressure, sodium excretion, and the renin-aldosterone system.
Topics: Adult; Aldosterone; Blood Pressure; Blood Volume; Creatinine; Diuretics; Heart Rate; Humans; Hyperte | 1979 |
The metabolic clearance of aldosterone decreases similarly during infusion of angiotensin II in patients with essential hypertension and in normal subjects.
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kinetics; Male; Metabolic Clearanc | 1979 |
Age- and sex-related differences in plasma aldosterone in essential hypertension. Relationship to plasma renin activity.
Topics: Adolescent; Adult; Age Factors; Aldosterone; Female; Furosemide; Humans; Hydrocortisone; Hypertensio | 1979 |
The adrenal cortex and arterial hypertension.
Topics: Adrenal Cortex Hormones; Aldosterone; Desoxycorticosterone; Extracellular Space; Humans; Hypertensio | 1979 |
Effects of bromocryptine on hormone and blood pressure levels in the spontaneously hypertensive rat.
Topics: Age Factors; Aldosterone; Animals; Blood Pressure; Body Weight; Bromocriptine; Corticosterone; Femal | 1979 |
[Conn's disease with an edematous form of chronic glomerulonephritis].
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Chronic Disease; Edema; Female; Glomerulonephritis; Hum | 1979 |
Effects of indomethacin on plasma renin activity, plasma aldosterone concentration, urinary prostaglandin E excretion and blood pressure in patients with essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypertensio | 1979 |
18-Hydroxy-11-deoxycorticosterone in hypertensive uremic patients during hemodialysis.
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Aged; Aldosterone; Desoxycorticosterone; Fe | 1979 |
Aldosterone and its stimuli in normal and hypertensive man: are essential hypertension and primary hyperaldosteronism without tumour the same condition?
Topics: Adenoma; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hyperaldosteronism; Hyp | 1979 |
Adrenocorticosteroids in experimental and human hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Animals; Biolo | 1979 |
[Acute combined alpha- and beta-adrenergic blockade in essential hypertension: effects on blood pressure, renal function, renin, and aldosterone].
Topics: Adult; Aldosterone; Blood Pressure; Diuresis; Drug Therapy, Combination; Female; Humans; Hypertensio | 1979 |
Angiotensin II in primary hypertension, relationship to plasma renin activity, aldosterone and urinary electrolytes.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Body Weight; Creatinine; Electrolytes; Female; Furosemide; | 1979 |
Observations on edema formation in the nephrotic syndrome in adults with minimal lesions.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Blood Volume; Creatinine; Edema; Female; Glomerular | 1979 |
Idiopathic, sustained, inappropriate secretion of ADH with associated hypertension and thirst.
Topics: Adolescent; Aldosterone; Diet; Drinking; Female; Humans; Hypertension; Inappropriate ADH Syndrome; O | 1979 |
Hypertension and aldosterone overproduction without renin suppression in Cushing's syndrome from an adrenal adenoma.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Corticosterone; Cushing Syndrome; Desoxycorti | 1979 |
Effect of nifedipine on plasma renin, aldosterone and catecholamines in arterial hypertension.
Topics: Adult; Aged; Aldosterone; Catecholamines; Evaluation Studies as Topic; Female; Hemodynamics; Humans; | 1979 |
[Hormonal contraceptives and high blood pressure (author's transl)].
Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Contraceptives, Oral; Contraceptives, Oral, Hormonal; E | 1979 |
Renin-aldosterone and vanillylmandelic acid in postpartum hypertension.
Topics: Aldosterone; Female; Humans; Hypertension; Posture; Pregnancy; Puerperal Disorders; Renin; Vanilmand | 1979 |
Vascular responsiveness to pressor agents during human pregnancy.
Topics: Aldosterone; Angiotensin II; Aspirin; Female; Hematocrit; Humans; Hypertension; Indomethacin; Pregna | 1979 |
The placenta and the renin-angiotensin system.
Topics: Aldosterone; Angiotensin II; Female; Fetus; Humans; Hypertension; Maternal-Fetal Exchange; Placenta; | 1979 |
Postural effects on renal function and volume homeostasis during pregnancy.
Topics: Adult; Aldosterone; Female; Glomerular Filtration Rate; Homeostasis; Humans; Hydrocortisone; Hyperte | 1979 |
[Salt restriction test].
Topics: Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Renin | 1979 |
[DOCA loading test].
Topics: Aldosterone; Desoxycorticosterone; Humans; Hyperaldosteronism; Hypertension | 1979 |
[Role of steroid hormones in the etiology and clinical course of hypertension].
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Female; Humans; Hydrocortisone; Hypertension; Male; | 1979 |
Genetic aspects of plasma aldosterone binding globulins in families of patients with essential hypertension, including isolation of novel thermostable homologues from plasma and urine.
Topics: Adolescent; Adult; Aged; Aldosterone; Canrenoic Acid; Carrier Proteins; Child; Child, Preschool; Fem | 1979 |
Adrenal sensitivity to angiotensin II and undiscovered aldosterone stimulating factors in hypertension.
Topics: Adrenal Glands; Adult; Aldosterone; Dexamethasone; Female; Humans; Hyperaldosteronism; Hypertension; | 1979 |
[A nephrologist's thoughts on pregnancy toxemia].
Topics: Aldosterone; Angiotensins; Edema; Female; Glomerular Filtration Rate; Glomerulonephritis; Humans; Hy | 1979 |
Volume studies in men with mild to moderate hypertension.
Topics: Adult; Aldosterone; Body Fluids; Body Water; Erythrocyte Volume; Extracellular Space; Heart Rate; Hu | 1979 |
Effect of prostaglandin E1 on renin and aldosterone in hypertensive patients.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Indomethacin; Male; Middle Aged; Propranolol; Pros | 1979 |
Abnormal adrenal responsiveness and angiotensin II dependency in high renin essential hypertension.
Topics: Adrenal Cortex; Adrenal Cortex Function Tests; Adult; Aldosterone; Angiotensin II; Blood Pressure; D | 1979 |
Effects of sodium loading and depletion in normotensive first-degree relatives of essential hypertensives.
Topics: Adult; Aldosterone; Creatinine; Female; Furosemide; Humans; Hypertension; Kidney; Kidney Function Te | 1979 |
Decreased hepatic delta 4-reductase activity for aldosterone in SHR [proceedings].
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aldosterone; Animals; Hypertension; Liver; Oxidoreductases; R | 1979 |
[Renin activity and the aldosterone and cortisol content in the blood depending on the course of hypertension].
Topics: Adult; Aldosterone; Blood Pressure; Chronic Disease; Coronary Disease; Enzyme Activation; Humans; Hy | 1979 |
Ticrynafen: a new thiazide-like but uricosuric antihypertensive diuretic.
Topics: Aldosterone; Animals; Glomerular Filtration Rate; Glycolates; Hemodynamics; Humans; Hypertension; Ki | 1979 |
Hypertension and hyperkalaemia responding to bendrofluazide.
Topics: Adult; Aldosterone; Arginine Vasopressin; Bendroflumethiazide; Diet, Sodium-Restricted; Furosemide; | 1979 |
Blood pressure reduction by incremental infusion of labetalol in patients with severe hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Ethanolamines; Female; Heart R | 1979 |
Minoxidil increases aldosterone metabolic clearance in hypertensive patients.
Topics: Adult; Aldosterone; Humans; Hypertension; Kidney Failure, Chronic; Metabolic Clearance Rate; Middle | 1979 |
[Nature of the reaction of blood plasma steroid hormones in hypertension to various types of stimulation].
Topics: Adolescent; Adult; Aldosterone; Furosemide; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; | 1979 |
Vaule of renin measurement, saralasin test, and acebutolol treatment in hypertension.
Topics: Acebutolol; Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet; Heart Rate; Humans | 1979 |
Aldosterone 18-glucuronide excretion determined with and without chromatography in human hypertensives.
Topics: Aldosterone; Chromatography, Paper; Circadian Rhythm; Glucuronates; Humans; Hypertension; Radioimmun | 1979 |
Renal kallikrein-kinin system and prostaglandin in hypertension: their relation to renin-angiotensin-aldosterone system.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensins; Diet, Sodium-Restricted; Female; Furosemide; Hum | 1979 |
Defect in kallikrein-kinin-system in essential hypertension and reduction of blood pressure by orally given kallikrein.
Topics: Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Kallikreins; Refe | 1979 |
Dissociation in the excretion of different aldosterone metabolites and unmetabolized ('free') aldosterone in hypertension.
Topics: 18-Hydroxycorticosterone; Aldosterone; Glucuronates; Humans; Hyperaldosteronism; Hypertension; Renal | 1979 |
Studies on the renin-angiotensin-aldosterone system in elderly hypertensive patients with an angiotensin II antagonist.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; F | 1979 |
Effect of oral labetalol on plasma catecholamines, renin and aldosterone in patients with severe arterial hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Catecholamines; Epinephrine; Ethanolamines; F | 1979 |
Haemodynamic effects of treatment and withdrawal of spironolactone in essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Body Weight; Cardiac Output; Creatini | 1979 |
Effect of triamterene on urinary excretion of immunoreactive prostaglandin E in essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Angiotensins; Blood Pressure; Female; Humans; Hypertension; Kidney; | 1979 |
[Sodium chloride and hypertension (an additional, temporary hypothesis)].
Topics: Aldosterone; Angiotensins; Animals; Body Weight; Diet, Sodium-Restricted; Disease Models, Animal; Hu | 1979 |
The renin-angiotensin-aldosterone system in hypertension: its biochemistry and applications.
Topics: Adult; Age Factors; Aldosterone; Amino Acid Sequence; Angiotensin II; Angiotensins; Female; Humans; | 1979 |
[Effect of hypotensive therapy depending on the blood level of steroid hormones and their reaction to diuretics].
Topics: Adolescent; Adult; Aldosterone; Furosemide; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension | 1979 |
[Clinical and experimental studies of plasma and urinary aldosterone determination].
Topics: Adult; Aged; Aldosterone; Evaluation Studies as Topic; Female; Humans; Hyperaldosteronism; Hypertens | 1977 |
[Low renin hypertension and aldosterone].
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Ren | 1977 |
[Simple determination of plasma aldosterone with aldosterone radioimmunoassay kit using 125I-aldosterone].
Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Iodine Radioisotopes; Male; Middle Age | 1977 |
[Effect of carbon baths on blood pressure level of aldosterone, renin, minerals in the blood and catecholamines in the urine of patients with essential hypertension].
Topics: Adult; Aldosterone; Balneology; Blood Pressure; Carbon; Catecholamines; Female; Humans; Hypertension | 1977 |
Diagnosis of secondary forms of hypertension. A comprehensive protocol.
Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Female; Furosemide; Humans; Hy | 1977 |
Radioimmunoassays of tetrahydroaldosterone (TH-aldo) in human urine.
Topics: Aldosterone; Antigens; Cross Reactions; Glucuronates; Humans; Hyperaldosteronism; Hypertension; Immu | 1978 |
Effect of an angiotensin II analogue upon blood pressure, plasma renin concentration and plasma aldosterone in hypertensive patients.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; | 1979 |
The application of neurologic reflexes to the treatment of hypertension.
Topics: Adult; Aldosterone; Humans; Hypertension; Male; Middle Aged; Osteopathic Medicine; Reflex; Renin | 1979 |
The renin-aldosterone system in exaggerated natriuresis of essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Natriuresis; Renin; Sodium; | 1977 |
[Pathophysiology of hypertension (author's transl)].
Topics: Aldosterone; Angiotensin II; Diagnosis, Differential; Humans; Hypertension; Renin | 1977 |
[Various humoral pressor and depressor systems in hypertension].
Topics: Adolescent; Adult; Aldosterone; Catecholamines; Diuresis; Humans; Hydrocortisone; Hypertension; Kall | 1977 |
[Plasma aldosterone concentration and vascular reactivity in hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Blood Vessels; Humans; Hypertension; Male; Middle Aged; Norepine | 1977 |
Effects of 1-Sar-8-Ile-angiotensin II on urinary prostaglandin excretion in patients with essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Female; Humans; Hypertensio | 1977 |
[Hyperkalemic, hyperchloremic acidosis in moderate chronic renal insufficiency and selective hypoaldosteronism].
Topics: Acidosis; Adult; Aged; Aldosterone; Chlorides; Female; Humans; Hyperkalemia; Hypertension; Kidney Fa | 1977 |
[The adrenergic system and the control of the renin and aldosterone circadian rhythm in essential arterial hypertension].
Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Female; Humans; Hydrocortisone; Hypertension; Male | 1977 |
[Circadian rhythm of renin and aldosterone in essential arterial hypertension].
Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Humans; Hydrocortisone; Hypertension; Renin | 1977 |
Influence of pentobarbitalnatrium (Nembutal) narcosis on blood pressure, plasma renin activity, aldosterone, sodium and potassium in normotensive and spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Hypertension; Pentobarbital; Potassium; Rats; Rat | 1977 |
[Liddle's syndrome].
Topics: Aldosterone; Alkalosis; Humans; Hypertension; Hypokalemia; Renin; Syndrome | 1977 |
[Modification of genetic hypertension in rats].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone; Denervation; Diet, Sodium-Rest | 1977 |
[What role does the renin-angiotensin system have in the pathogenesis of hypertension?].
Topics: Aldosterone; Angiotensin II; Animals; Corticosterone; Desoxycorticosterone; Extracellular Space; Hyp | 1977 |
[Relationship between plasma noradrenaline (PNA), plasma renin activity (PRA), plasma aldosterone (PAC) and sodium excretion (U-Na+) in primary hypertension].
Topics: Aldosterone; Humans; Hypertension; Norepinephrine; Renin; Sodium | 1977 |
[Diagnostic ability of the renin-angiotensin-aldosterone-system (R.A.A.-system) stimulation as a screening test in hypertension].
Topics: Aldosterone; Angiotensin II; Diagnosis, Differential; Furosemide; Humans; Hypertension; Hypertension | 1977 |
[Hemodynamics, renin and aldosterone following angiotensin II blockade and sodium chloride deficiency in hypertensive subjects].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Diet, Sodium-Restricted; Heart Rate; He | 1977 |
[Kidney function in essential hypertension].
Topics: Aldosterone; Blood Pressure; Diuresis; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Nat | 1977 |
[Correlations between plasma volume, hemodynamic indices and hematochemical parameters in hypertensive patients (proceedings)].
Topics: Aldosterone; Hemodynamics; Humans; Hypertension; Plasma Volume; Renin | 1977 |
The role of adrenal mineralocorticoids in hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hyperplas | 1978 |
Aldosterone in the exaggerated natriuresis of spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Body Water; Diet; Extracellular Space; Hypertension; Kidney; Male; Natriuresis | 1978 |
The integrated concentration of plasma renin activity and aldosterone in essential hypertension.
Topics: Adult; Aged; Aldosterone; Furosemide; Humans; Hypertension; Male; Middle Aged; Renin | 1978 |
[Oral contraceptives, hypertension and nephrosclerosis].
Topics: Adult; Aldosterone; Animals; Blood Coagulation; Contraceptives, Oral; Estrogens; Female; Humans; Hyp | 1978 |
Effect of saralasin on plasma aldosterone in hypertensive man.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Furosemide; Humans; Hypertension; Hypert | 1978 |
The possible importance of aldosterone as well as renin in the long-term antihypertensive action of propranolol.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Depression, Chemical; Female; Humans; Hypertension; Male; | 1978 |
The effect of high-sodium and low-sodium intakes on blood pressure and other related variables in human subjects with idiopathic hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Blood Volume; Body Weight; Diet; Humans; Hypertension; Middle Ag | 1978 |
Effect of furosemide on urinary kallikrein excretion in patients with essential hypertension.
Topics: Adult; Aldosterone; Female; Furosemide; Humans; Hypertension; Kallikreins; Male; Middle Aged; Potass | 1978 |
The multiple factors affecting plasma renin activity in essential hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Dopamine beta-Hydroxylase; Epinephrine; Female; Furosemide; Hu | 1978 |
Familial hyperkalemia, hypertension, and hyporeninemia with normal aldosterone levels. A tubular defect in potassium handling.
Topics: Acidosis; Adrenal Glands; Aldosterone; Humans; Hyperkalemia; Hypertension; Kidney; Male; Middle Aged | 1978 |
The effect of an angiotensin antagonist (saralasin) on arterial pressure and plasma aldosterone in hemodialysis-resistant hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Filtration; Humans; Hypertension; Male; | 1978 |
Use of the angiotensin I antagonist, SQ 20881, for lateralizing renal venous renin activity.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensins; Blood; Blood Pressure; Humans; Hyperten | 1978 |
Changes in renal function in essential hypertension.
Topics: Aldosterone; Blood Pressure; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; | 1978 |
Comparison of the antihypertensive and hormonal effects of a cardioselective beta-blocker, acebutolol, and diuretics in essential hypertension.
Topics: Acebutolol; Adult; Aldosterone; Amiloride; Blood Pressure; Dose-Response Relationship, Drug; Drug Th | 1978 |
Relative significance of plasma renin activity and concentration in physiologic and pathophysiologic conditions.
Topics: Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Diet; Diet, Sodium-Restricted; Female; Humans | 1978 |
The pressor response to angiotensin II in patients with low renin essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Urea Nitrogen; Humans; Hyperaldosteronism; | 1978 |
[Biochemical profile of essential arterial hypertension. Indications for a targeted therapy: experience with propranolol].
Topics: Aldosterone; Drug Evaluation; Humans; Hypertension; Propranolol; Renin | 1978 |
Aldosterone responsiveness in patients with diabetes mellitus.
Topics: Aldosterone; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Electrolytes; Female | 1978 |
Increased adrenal sensitivity to angiotensin II in low-renin essential hypertension.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Female; Furosemide; Humans; Hypertension; Male; | 1978 |
Plasma renin activity, aldosterone and sodium excretion in women with high and low casual blood pressure levels.
Topics: Adolescent; Aged; Aldosterone; Blood Pressure Determination; Female; Humans; Hypertension; Middle Ag | 1978 |
An approach to mineralocorticoid hormone hypertension.
Topics: Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Aldosterone; Cushing Syndrome; Desoxy | 1978 |
Adrenal steroidogenesis and hepatic corticosteroid metabolism in hypertensive rats.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Animals | 1978 |
[Studies on kallikrein-kinin system in essential hypertension: urinary kallikrein-kinin system and renin-angiotensin-aldosterone system (author's transl)].
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Kallikreins; Kinins; Male; Middle Aged; Renin | 1978 |
Comparison of the biological effects of two angiotensin II analogues in hypertensive patients with sodium depletion.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Renin; S | 1978 |
[The renin-angiotensin-aldosterone system and hypertensive syndromes].
Topics: Aldosterone; Angiotensins; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Renin | 1978 |
[Role of aldosterone in the pathogenesis of spontaneous (hereditarily determined) hypertension in rats].
Topics: Age Factors; Aldosterone; Animals; Body Weight; Hypertension; Rats; Rats, Inbred Strains | 1978 |
[The urologist and hypertension].
Topics: Acute Disease; Aldosterone; Angiotensins; Central Nervous System; Child; Humans; Hypertension; Hyper | 1978 |
Failure of chronic aldosterone infusion to increase arterial pressure in dogs with angiotensin-induced hypertension.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Computers; Dogs; Hematocrit; Hy | 1978 |
Subpressor angiotensin infusion, renal sodium handling, and salt-induced hypertension in the dog.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Furose | 1978 |
[The effect of cortisol infusion on plasma renin activity, aldosterone levels and 11-deoxycorticosterone levels in humans (author's transl)].
Topics: Adolescent; Adult; Aldosterone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hyperaldostero | 1978 |
Influence of sodium intake on hydrochlorothiazide-induced changes in blood pressure, serum electrolytes, renin and aldosterone in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Humans; Hydrochlorothiazid | 1978 |
Effects of 1-sar-8-ala-angiotensin II on arterial pressure, renin and aldosterone in hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet; Female; Humans; Hypertension; Male; Renin; | 1978 |
Antihypertensive effect of volume depletion: interrelation with renal prostaglandins.
Topics: Aldosterone; Animals; Blood Pressure; Furosemide; Humans; Hypertension; Indomethacin; Kidney; Kidney | 1978 |
Implication of renal prostaglandin E in urinary sodium excretion.
Topics: Adolescent; Adult; Aged; Aldosterone; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Prost | 1978 |
Aldosterone in primary hypertension relationship to plasma renin activity and urinary electrolytes and a comparison with normotensive subjects.
Topics: Adult; Aged; Aging; Aldosterone; Blood Pressure; Electrolytes; Female; Humans; Hypertension; Male; M | 1978 |
[Individual renal blood flow and activity of the renin-aldosterone system in patients with renovascular hypertension and hypertensive disease].
Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Renin | 1978 |
Role of renin and aldosterone suppression in the antihypertensive mechanism of clonidine.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Clonidine; Female | 1978 |
Use of diuretics in treatment of hypertension secondary to renal disease.
Topics: Adult; Aldosterone; Antihypertensive Agents; Creatinine; Female; Furosemide; Humans; Hydrochlorothia | 1978 |
Hypertension and oral contraceptives.
Topics: Aldosterone; Contraceptives, Oral; Female; Humans; Hypertension; Mineralocorticoids; Renin | 1978 |
Role of aldosterone in the antihypertensive effect of spironolactone in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Electrolytes; Female; Humans; Hypertension; Kidney; | 1978 |
[Saralasin for renovascular or essential hypertension (author's transl)].
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Hypert | 1978 |
Plasma mineralocorticoids, plasma renin, and urinary kallikrein in salt-sensitive and salt-resistant rats.
Topics: 18-Hydroxydesoxycorticosterone; Aldosterone; Animals; Blood Pressure; Body Weight; Corticosterone; D | 1978 |
[Studies of urinary kallikrein in patients with various types of hypertension (relationship to renin-angiotension-aldosterone system (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kallikreins; Kidney Diseases; Male | 1978 |
[Study on etiology of hypertension in patients on chronic hemodialysis (author's transl)].
Topics: Adult; Aldosterone; Dopamine beta-Hydroxylase; Humans; Hypertension; Middle Aged; Renal Dialysis; Re | 1978 |
[Saralasin-induced changes of blood pressure, renin and aldosterone in essential and renal hypertension (author's transl)].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Hypertension, Renal; Renin; Saral | 1978 |
[New differential diagnostic and therapeutic possibilities in arterial hypertension].
Topics: Adult; Aldosterone; Antihypertensive Agents; Diagnosis, Differential; Humans; Hypertension; Hyperten | 1978 |
[Long-term minoxidil therapy: renin, aldosterone, noradrenaline and the need for beta blockers].
Topics: Adult; Aldosterone; Chlorthalidone; Female; Furosemide; Hirsutism; Humans; Hypertension; Male; Middl | 1978 |
Blood pressure, renin-angiotensin system and urinary kallikrein in a case of juxtaglomerular cell tumor.
Topics: Acebutolol; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Half-Life; Humans; Hypertens | 1978 |
Familial hyperpotassemia and hypertension accompanied by normal plasma aldosterone levels: possible hereditary cell membrane defect.
Topics: Adult; Aldosterone; Cell Membrane; Humans; Hyperkalemia; Hypertension; Insulin; Kidney Function Test | 1978 |
Proximal renal tubular acidosis: association with familial normaldosteronemic hyperpotassemia and hypertension.
Topics: Acidosis, Renal Tubular; Adult; Aldosterone; Child; Child, Preschool; Female; Humans; Hyperkalemia; | 1978 |
[Renin-angiotensin-aldosterone system and electrolytes metabolism on furosemide stimulation test (author's transl)].
Topics: Aldosterone; Diet, Sodium-Restricted; Electrolytes; Furosemide; Humans; Hypertension; Renin | 1978 |
Studies on hypertension: changes of humoral factors under long-term administration of thiazide.
Topics: Aldosterone; Animals; Benzothiadiazines; Catecholamines; Diuretics; Hypertension; Rats; Renin; Sodiu | 1978 |
[Responses of renin-angiotensin-aldosterone system to insulin hypoglycemia in patients with essential hypertension (author's transl)].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypoglycemia; Insulin; Male; | 1978 |
Aldosterone diagnosis in hypertension: comparative evaluation of radioimmunoassays for urinary aldosterone and 18-OH-corticosterone.
Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Aldosterone; Chromatography; Corticosteron | 1978 |
Blood pressure responses to extremes of sodium intake in normal man.
Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Diet; Diuresis; Humans; Hypertension; Kidney; Male; | 1978 |
The effect of the converting enzyme inhibitor SQ 20.881 on kinins, renin-angiotensin-aldosterone and catecholamines in relation to blood pressure in hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Catecholamines; Epinephrine; Female; Humans; Hyp | 1978 |
Effects of furosemide on plasma renin and aldosterone in three subtypes of essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Renin; | 1978 |
Kinetic variations of plasma renin and aldosterone during active orthostatism in three subtypes of essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Posture; | 1978 |
[Effect of oral sodium load on the renin and aldosterone secretion in essential hypertension. Comparison to normal persons].
Topics: Aldosterone; Hypertension; Renin; Sodium | 1978 |
[Total body potassium in low renin essential hypertension with reference to the renin-angiotensin-aldosterone system (author's transl)].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kidney; Male; Middle Aged; P | 1978 |
[Studies on renal prostaglandin E in essential hypertension: relationships among urinary prostaglandin E, sodium balance, renin-angiotensin-aldosterone system and renal kallikrein-kinin system (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kallikreins; Kidney; Male; Prostag | 1978 |
[Plasma prostaglandins and the renin-aldosterone system in patients with labile or permanent essential hypertension].
Topics: Adult; Aldosterone; Electrolytes; Humans; Hypertension; Kidney; Plasma Volume; Prostaglandins E; Pro | 1978 |
[Mechanism of sodium retention in nephrotic syndrome: role of aldosterone and glomerular filtration].
Topics: Aldosterone; Glomerular Filtration Rate; Humans; Hypertension; Kidney Glomerulus; Natriuresis; Nephr | 1978 |
Age versus urinary sodium for judging renin, aldosterone, and catecholamine levels: studies in normal subjects and patients with essential hypertension.
Topics: Adolescent; Adult; Age Factors; Aged; Aldosterone; Catecholamines; Epinephrine; Female; Humans; Hype | 1978 |
The characterization of low renin hypertension by plasma renin activity and plasma aldosterone concentration.
Topics: Adult; Aged; Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Mathematics; Middle Aged; R | 1978 |
Sodium metabolism in essential hypertension. Natriuretic response to acute hypertonic saline load.
Topics: Aldosterone; Blood Pressure; Blood Proteins; Humans; Hydrocortisone; Hypertension; Kidney Tubules; N | 1978 |
Evidence for an angiotensinogenic mechanism of the hypertension of Cushing's syndrome.
Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure; | 1978 |
Interrelations between plasma renin activity, aldosterone, and sympathetic nervous system activity in essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Dopamine beta-Hydroxylase; Female; Humans; Hydrocortisone; Hypertens | 1978 |
Relationship of basal plasma norepinephrine to blood pressure, plasma renin activity, mineralocorticoids, and plasma volume in essential hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Ma | 1978 |
[Effect of guanabenz on arterial pressure and the renin-aldosterone system in hypertensive patients].
Topics: Adult; Aged; Aldosterone; Blood Pressure; Guanabenz; Guanidines; Heart Rate; Humans; Hypertension; H | 1978 |
The effect of indomethacin on plasma renin activity and urinary aldosterone of patients with essential hypertension.
Topics: 17-Ketosteroids; Adult; Aldosterone; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Hype | 1978 |
Renin-angiotensin-aldosterone system in long-term renal transplant patients.
Topics: Adult; Aldosterone; Angiotensin II; Animals; Diet, Sodium-Restricted; Dogs; Follow-Up Studies; Human | 1976 |
Plasma renin activity (PRA) and plasma aldosterone (PA) in hypertensive kidney allograft recipients.
Topics: Aldosterone; Humans; Hypertension; Kidney Transplantation; Postoperative Complications; Renin; Sodiu | 1976 |
Plasma renin, plasma aldosterone, exchangeable sodium and renal hemodynamics in normotensive and hypertensive recipients of a kidney transplant with and without transplant renal artery stenosis.
Topics: Aldosterone; Blood Pressure; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal; | 1976 |
[Equilibration of the treatment of severe arterial hypertension. Significance of d-1 propranolol].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Heart Rate; Humans; Hydralazine; Hypertension; Long-Ter | 1975 |
Renin-angiotensin-aldosterone system in diabetes mellitus.
Topics: Aldosterone; Angiotensin II; Animals; Blood Volume; Diabetes Mellitus; Diabetes Mellitus, Experiment | 1976 |
Study of aldosterone levels in plasma during pregnancy.
Topics: Aldosterone; Female; Humans; Hypertension; Menstruation; Methods; Parity; Pregnancy; Pregnancy Compl | 1977 |
[Importance of the simultaneous estimation of aldosterone, 18-hydroxy-11-deoxycorticosterone and cortisol in the adrenal veins in arterial hypertension with suppressed renin (author's transl)].
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Glands; Aldosterone; Desoxycorticosterone; Humans; Hydrocort | 1977 |
Renin reactivity as a determinant of responsiveness to antihypertensive treatment.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Body Weight; Chlorthalidone; Drug | 1977 |
[Effect of dietary salt restriction and erect posture on plasma renin activity and aldosteronemia in patients with essential hypertension].
Topics: Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Posture; Renin | 1977 |
Natriuretic response to saline infusion in normotensive and hypertensive man. The role of renin suppression in exaggerated natriuresis.
Topics: Adolescent; Adult; Aged; Aldosterone; Female; Furosemide; Humans; Hyperaldosteronism; Hypertension; | 1977 |
An abnormality in steroid reductive metabolism in a hypertensive syndrome.
Topics: Aldosterone; Cortisone; Glucocorticoids; Humans; Hydrocortisone; Hypertension | 1977 |
Influence of thiazide on salt hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Chlorothiazide; Hypertension; Male; Natriuresis; Rats; Renin; | 1977 |
Isolation of a hypertension-producing compound from normal human urine.
Topics: Aldosterone; Animals; Blood Pressure; Blood Volume; Heart Rate; Humans; Hypertension; Kidney; Molecu | 1977 |
[Metoprolol in essential arterial hypertension].
Topics: Adult; Aldosterone; Diet; Drug Evaluation; Female; Humans; Hypertension; Male; Metoprolol; Middle Ag | 1977 |
Alloxan diabetes in spontaneously hypertensive rats: gravimetric, metabolic and histopathological alterations.
Topics: Aldosterone; Animals; Body Weight; Cardiovascular Diseases; Corticosterone; Diabetes Mellitus, Exper | 1977 |
Prostaglandins and the renal antihypertensive function.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Furosemide; Humans; Hypertension; Ind | 1977 |
Evaluation of patients for secondary hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Female; Hospitalization; Humans; Hyperaldosteronism; Hypertens | 1977 |
[Aldosteronemia and plasma renin activity in patients with hypertension treated with visken (prindolol)].
Topics: Aldosterone; Humans; Hypertension; Pindolol; Renin | 1977 |
The physiology of blood pressure regulation--normal and abnormal.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Child; Glomerular Filtration Rate; Hemo | 1977 |
[Radioimmunological determination of aldosterone in the serum. New method for the localization of aldosteronism].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Posture; Radioimmunoassay; Renin | 1977 |
Steroid profile in a case of adrenal carcinoma with severe hypertension.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Aldost | 1977 |
Production of sustained hypertension by chronic intrarenal norepinephrine infusion in conscious dogs.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female | 1977 |
Multifactorial analysis of chronic hypertension induced by electrolyte-active steroids in trained, unanesthetized dogs.
Topics: Acebutolol; Aldosterone; Animals; Chronic Disease; Clonidine; Corticosterone; Diet, Sodium-Restricte | 1977 |
Evidence for an unidentified steroid in a child with apparent mineralocorticoid hypertension.
Topics: 17-Ketosteroids; Aldosterone; Blood Pressure; Body Weight; Child, Preschool; Chlorothiazide; Dexamet | 1977 |
Aldosterone regulation in essential hypertension: altered adrenal responsiveness to angiotensin II.
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Infusions, Parenteral; Male; Postu | 1977 |
Altered renin-angiotensin-aldosterone relationships in normal renin essential hypertension.
Topics: Adrenal Cortex; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; | 1977 |
[The value of stimulation of the renin-angiotensin-aldosterone system as a screening test for hypertension (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Diuretics; Furosemide; Humans; Hypertension; Male; Middle Aged; | 1977 |
The antihypertensive action of methyldopa in relation to its effect on the renin-aldosterone system.
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Body Weight; Humans; Hypertension; Hypertensio | 1977 |
Aids in the diagnosis of hypertension.
Topics: Aldosterone; Angiotensin II; Cardiovascular Diseases; Diuretics; Humans; Hyperaldosteronism; Hyperte | 1977 |
Experimental aldosterone hypertension in the rat.
Topics: Aldosterone; Animals; Blood Pressure; Chlorisondamine; Desoxycorticosterone; Drug Interactions; Etha | 1977 |
[Pattern of aldosterone and catecholamines in patients with essential hypertension and differnet plasma renin activity].
Topics: Adult; Aldosterone; Catecholamines; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1977 |
Low renin hypertension.
Topics: Adrenal Cortex; Aldosterone; Humans; Hydrocortisone; Hypertension; Metal Metabolism, Inborn Errors; | 1977 |
[Stimulation of renin-angiotensin-aldosterone system as screening test for hypertension].
Topics: Aldosterone; Angiotensin II; Furosemide; Humans; Hypertension; Methods; Propranolol; Renin | 1977 |
Age- and posture-related changes in plasma protein binding and metabolism of aldosterone in essential and secondary hypertension.
Topics: Adolescent; Adult; Age Factors; Aldosterone; Blood Proteins; Female; Humans; Hypertension; Male; Met | 1977 |
Frequency of surgical treatment for hypertension in adults at the Mayo Clinic from 1973 through 1975.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Female; Humans; Hypertension | 1977 |
[The effect of upright posture on plasma aldosterone concentration in arterial hypertension (author's transl)].
Topics: Aldosterone; Humans; Hypertension; Posture | 1977 |
Influence of beta-blockade on aldosterone metabolism under normal and low sodium diet in man.
Topics: Acebutolol; Adult; Aldosterone; Angiotensins; Diet, Sodium-Restricted; Humans; Hypertension; Male; M | 1977 |
[The renin-angiotensin-aldosterone system in hypertensive patients. II. Diagnosis of primary hyperaldosteronism].
Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adult; Aldosterone; Blo | 1977 |
Urinary kallikrein in normal renin essential hypertension.
Topics: Adult; Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Kallikreins; Male; Renin; Sodium | 1977 |
[The renin-aldosterone system in essential hypertension--aging, low renin hypertension and the relation between renin secretion and aldosterone secretion--].
Topics: Adult; Aged; Aging; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Middle Aged; Renin | 1977 |
[Effects of an analogue of angiotensin II, [Sar1,Ile8] ATII, on blood pressure, plasma renin activity and plasma aldosterone in various forms of hypertension].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Hypertension | 1977 |
[Effects of acute sodium depletion on blood pressure and renin-angiotensin-aldosterone system in patients with benign essential hypertension (author's transl)].
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Electrolytes; Female; H | 1977 |
Inappropriate secretion of antiduretic hormone, hypertension, and hypoplastic corpus callosum.
Topics: Adolescent; Agenesis of Corpus Callosum; Aldosterone; Angiotensin II; Arginine Vasopressin; Blood Pr | 1977 |
Disparate patterns of aldosterone response during diuretic treatment of hypertension.
Topics: Adult; Aldosterone; Body Weight; Chlorthalidone; Female; Humans; Hypertension; Male; Middle Aged; Pu | 1977 |
Age and the renin-aldosterone system.
Topics: Adolescent; Adult; Age Factors; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Mid | 1977 |
[Antihypertensive effects of coenzyme Q10 in essential hypertension--in relation to the renin-aldosterone system].
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Female; Humans; Hypertension; Male; Middle Aged; | 1977 |
Retardation in the development of spontaneous hypertension in SH rats by gonadectomy.
Topics: Adrenal Glands; Aldosterone; Animals; Body Weight; Castration; Corticosterone; Desoxycorticosterone; | 1977 |
The renin-angiotensin system in hypertension.
Topics: Aldosterone; Angiotensins; Diuretics; Humans; Hypertension; Juxtaglomerular Apparatus; Propranolol; | 1977 |
[The renin-angiotensin-aldosterone system in essential arterial hypertension].
Topics: Adolescent; Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Female; Furosemide; Humans; Hyper | 1977 |
[The effects of clonidine on the renin-angiotensin-aldosterone system in patients with hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Clonidine; Drug Evaluation; Female; Humans; Hype | 1977 |
Factors influencing the choice of antihypertensive agents.
Topics: Age Factors; Aldosterone; Cerebrovascular Disorders; Clonidine; Depression; Diabetes Complications; | 1976 |
[Simple determination of urinary aldosterone without chromatography].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Radioimmunoassay | 1976 |
Nomograms relating aldosterone excretion to urinary sodium and potassium in the pediatric population: their application to the study of childhood hypertension.
Topics: Adolescent; Adult; Aldosterone; Child, Preschool; Circadian Rhythm; Humans; Hypertension; Infant; In | 1976 |
Dissociation of plasma renin activity and aldosterone in essential hypertension.
Topics: Adolescent; Adult; Age Factors; Aldosterone; Humans; Hypertension; Middle Aged; Renin | 1976 |
[Recent progress concerning the pathogenesis of arterial hypertension].
Topics: Affective Symptoms; Aldosterone; Blood Pressure; Elasticity; Heart Rate; Humans; Hyperaldosteronism; | 1976 |
Renin, aldosterone and arterial pressure responses to acute beta-adrenergic receptor blockage in hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Circadian Rhythm; Humans; Hypertension; Male; Pindolol; Proprano | 1976 |
[Significance of certain humoral factors in the pathogenesis of hypertension in pregnancy].
Topics: Aldosterone; Female; Humans; Hypertension; Potassium; Pregnancy; Pregnancy Complications, Cardiovasc | 1976 |
A delayed suppression of the renin-aldosterone axis following saline infusion in human hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Female; Humans; Hypertension; Infus | 1976 |
Clinical pharmacology of angiotensin antagonists.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Humans; Hypertension; Radioimmunoassa | 1976 |
The effect of saralasin (1sar-8-ala-angiotensin II) on blood pressure in patients with Cushing's syndrome.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Cushing Syndrome; Female; Humans; Hyperaldosteronism; H | 1976 |
Reciprocal relation between renin dependency and sodium dependency in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Feedback; Humans; Hypertension; Kidney; Middle A | 1976 |
[Relationship between hormone concentration in peripheral blood in hypertension, arteriosclerosis and obesity].
Topics: Adult; Aldosterone; Arteriosclerosis; Female; Hormones; Humans; Hydrocortisone; Hypertension; Insuli | 1976 |
[A critical review of hypothetical causes of EPH-gestosis].
Topics: Aldosterone; Angiotensin II; Animals; Biogenic Amines; Blood Volume; Body Fluids; Edema; Female; Fib | 1976 |
Relationship between plasma aldosterone concentration and plasma potassium in patients with essential hypertension during alprenolol treatment.
Topics: Adult; Aldosterone; Alprenolol; Blood Pressure; Female; Humans; Hypertension; Male; Potassium; Renin | 1976 |
The renal prostaglandins and blood pressure regulation.
Topics: Aldosterone; Binding Sites; Blood Pressure; Diuresis; Furosemide; Humans; Hypertension; Indomethacin | 1976 |
Benign desoxycorticosterone-producing adrenal tumor.
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Cholesterol; Desoxycorticosterone; Female; Humans; Hydr | 1976 |
[Evaluation of plasma remin activity and urinary excretion of aldosterone in subjects with clinically essential hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1976 |
[Sodium, hypertension and diuretics].
Topics: Aldosterone; Angiotensin II; Benzothiadiazines; Diuretics; Humans; Hypertension; Renin; Sodium; Sodi | 1976 |
Renin and aldosterone suppression in the antihypertensive action of clonidine.
Topics: Adult; Aldosterone; Clonidine; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle A | 1976 |
Acute and chronic dose-response relationships for angiotensin, aldosterone, and arterial pressure at varying levels of sodium intake.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Diet; Dogs; Dose-Response Relationship, Drug; | 1976 |
Studies of the renin-angiotension-aldosterone system, cortisol, DOC, and ADH in normal and hypertensive pregnancy.
Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Angiotensinogen; Arginine Vasopressin; Cortico | 1976 |
Sequential changes in the renin--angiotensin--aldosterone systems and plasma progesterone concentration in normal and abnormal human pregnancy.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy | 1976 |
[Endocrine disorders in patients with essential hypertension].
Topics: Aldosterone; Angiotensin II; Catecholamines; Humans; Hypertension; Prostaglandins; Renin | 1976 |
[Effect of diazoxide on blood pressure, PRA and plasma aldosterone in hypertensive patients (author's transl)].
Topics: Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Diazoxide; Humans; Hyperaldosteronism; Hyperte | 1976 |
[Evaluation of the plasma renin activity and urinary aldosterone excretion in patients with essential hypertension treated with spironolactone. Note II].
Topics: Adult; Aldosterone; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged; Renin; Spirono | 1976 |
[Plasma renin activity and plasma aldosterone in essential hypertension: effect of age and diastolic blood pressure].
Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Creatinine; Furosemide; Humans; Hypertension; Middle Ag | 1976 |
[Physiopathology of arterial hypertension. Role of the nervous system and of the hormones].
Topics: Aldosterone; Animals; Bradykinin; Brain; Catecholamines; Hormones; Humans; Hyperaldosteronism; Hyper | 1976 |
[Rectal electrical potential difference and plasma aldosterone in hyperaldosteronism and low-, normal- and high-renin hypertension].
Topics: Action Potentials; Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 1976 |
[Relationship between renin-aldosterone system and efficacy of a beta-blocking agent in hypertensive patients].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle | 1976 |
Changes of blood pressure, plasma renin activity and plasma aldosterone concentration following the infusion of Sar1-Ile8-angiotensin II in hypertensive, fluid and electrolyte disorders.
Topics: Acidosis, Renal Tubular; Aldosterone; Angiotensin II; Bartter Syndrome; Blood Pressure; Cushing Synd | 1976 |
The effects of the angiotensin II antagonist saralasin on blood pressure and plasma aldosterone in man in relation to the prevailing plasma angiotensin II concentration.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Diet; Humans; Hyperaldosteronism; Hypertension; Kidney | 1976 |
[Relationship between plasma-renin and plasma-aldosterone in patients with essential hypertension and in healthy persons].
Topics: Aldosterone; Humans; Hypertension; Posture; Renin | 1976 |
[Aldosterone excretion, cortisol and corticosterone plasma concentration in patients with essential hypertension under sodium load].
Topics: Aldosterone; Corticosterone; Humans; Hydrocortisone; Hypertension; Sodium | 1976 |
[Influence of propranolol on plasma-renin activity, plasma-aldosterone concentration and blood pressure in patients with essential hypertension].
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Propranolol; Renin | 1976 |
[Acute and chronic beta-receptor blockade: influence on blood pressure and on the renin-angiotensin-aldosterone system in essential hypertension].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Pindolol; Propranolol; Pulse; Ren | 1976 |
[Correlations between plasmatic renin and aldosterone in essential arterial hypertension with sympathetic hyperactivity].
Topics: Aldosterone; Female; Humans; Hypertension; Male; Renin; Sympathetic Nervous System | 1976 |
[Plasma aldosterone and renin activities in various types of hypertension].
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1976 |
[Changes of arterial pressure and biosynthesis of corticosteroids in rats with neurogenic stress].
Topics: Aldosterone; Animals; Blood Pressure; Corticosterone; Desoxycorticosterone; Humans; Hypertension; Ma | 1976 |
The renal humoral system: a cause of hypertension?
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Kidney; Renin | 1975 |
Hypertension and renal diseases.
Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Humans; Hypertension; Hypertension, Malignant; | 1975 |
Outpatient screening tests for primary aldosteronism.
Topics: Adolescent; Adult; Aged; Aldosterone; Fludrocortisone; Humans; Hyperaldosteronism; Hypertension; Mid | 1976 |
Aldosterone excretion rate in normal subjects and hypertensive patients.
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Sodium | 1976 |
The effects of saralasin, an angiotensin II antagonist, on blood pressure and the renin-angiotensin-aldosterone system in normal and hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Depression, Chemical; Diet; Female; Humans; Hype | 1976 |
Effects of aldosterone and spironolactone on arterial renin in rats.
Topics: Aldosterone; Animals; Aorta; Hypertension; Male; Rats; Renin; Spironolactone; Subcellular Fractions | 1976 |
Solitary kidney and ageing as causes of low renin and aldosterone concentrations: relevance to "low-renin" essential hypertension.
Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Glomerular Filtration Rate; Humans; Hypertension; Kidne | 1976 |
Determination of renin-dependency and sodium-dependency in the three renin sub-groups of essential hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Renin; Saralasin; Sodium | 1976 |
Synthesis of endocrine control in hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dogs; Feedback; Hypertension; Kidney; Potassiu | 1976 |
Role of steroids in hypertension: evaluation of plasma mineralocorticoid activity with aldosterone receptors.
Topics: Aldosterone; Animals; Binding, Competitive; Desoxycorticosterone; Humans; Hydrocortisone; Hypertensi | 1976 |
Haemodynamic and endocrinological changes during anti-hypertensive treatment with a new vasodilator substance (L6150) and propranolol.
Topics: Adult; Aged; Aldosterone; Cardiac Output; Drug Therapy, Combination; Female; Humans; Hypertension; K | 1976 |
The use of angiotensin-converting enzyme inhibitor in the diagnosis and treatment of hypertension.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Drug Evaluation; Female; Hu | 1975 |
18-hydroxylated steroids in human hypertension - clinical study.
Topics: 18-Hydroxydesoxycorticosterone; Adolescent; Adult; Aged; Aldosterone; Female; Humans; Hydroxylation; | 1976 |
Mineralocorticoid like effect of new 18-hydroxy-steroid isolated from urine of hypertensive patients.
Topics: 18-Hydroxydesoxycorticosterone; Adrenalectomy; Aldosterone; Animals; Hydroxylation; Hydroxyprogester | 1976 |
Role of juxtagolmerular apparatus in renal allograft rejection.
Topics: Aldosterone; Angiotensin II; Animals; Dogs; Erythropoietin; Glomerular Filtration Rate; Graft Reject | 1975 |
Renin and hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Diuretics; Hyperaldosteronism; Hypertension; Juxtaglome | 1975 |
Hypertension corrected by discontinuing chronic sodium bicarbonate ingestion. Subsequent transient hypoaldosteronism.
Topics: 17-Hydroxycorticosteroids; Aldosterone; Angiotensin II; Antihypertensive Agents; Bicarbonates; Calci | 1975 |
Adrenal steroidogenesis in the spontaneously hypertensive rat (SHR).
Topics: Adrenal Cortex Hormones; Adrenal Glands; Age Factors; Aldosterone; Animals; Catheterization; Cortico | 1975 |
[Changes in the biosynthesis of corticosteroids from progesterone-C14 under the effect of prostaglandin E2 in rabbits with vasorenal hypertension].
Topics: Adrenal Glands; Aldosterone; Animals; Carbohydrate Metabolism; Carbon Radioisotopes; Corticosterone; | 1975 |
Workup of the newly discovered hypertensive patient.
Topics: Adult; Aldosterone; Angiotensin II; Cardiac Output; Cerebrovascular Disorders; Contraceptives, Oral; | 1975 |
Role of blood pressure in cardiovascular disease: the Framingham Study.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Cardiovascular Diseases; Cholesterol; Coronary Disease; De | 1975 |
Pathophysiology of angiotensin-salt hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Urea Nitrogen; Body Weight; Calcium; Corticosterone; Des | 1975 |
Suppression of renin and aldosterone by small amounts of DOCA in normal man.
Topics: Adult; Aldosterone; Body Weight; Depression, Chemical; Desoxycorticosterone; Diet, Sodium-Restricted | 1975 |
Effects of high and low sodium intake on arterial pressure and forearm vasular resistance in borderline hypertension. A preliminary report.
Topics: Adult; Aldosterone; Blood Flow Velocity; Blood Pressure; Body Weight; Central Venous Pressure; Creat | 1975 |
[Renin, angiotensin and aldosterone in the diagnosis of hypertension].
Topics: Aldosterone; Angiotensin II; Blood Volume; Diagnosis, Differential; Humans; Hypertension; Hypertensi | 1975 |
[Essential hypertension and the renin-angiotensin-aldosterone system].
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Humans; Hypertension; Middle Aged; Renin | 1975 |
Plasma renin and aldosterone in an abdominal pregnancy with toxemia.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Ischemia; Placenta; Pre-Eclampsia; Pregnancy; Preg | 1975 |
Editorial: Low renin "essential'' hypertension; a variant of classic primary aldosteronism?
Topics: Adrenal Cortex; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 1975 |
Control of aldosterone secretion in the spontaneously hypertensive rat.
Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone; Hyperte | 1975 |
Proceedings: Steroid production rates in two patients with corticosterone-producing adenomata.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Corticosterone; Female; Hum | 1975 |
Effect of acute volume depletion on blood pressure, plasma renin activity and plasma aldosterone concentration in hypertensive subjects.
Topics: Acute Disease; Adolescent; Adult; Aldosterone; Blood Pressure; Body Fluids; Electrolytes; Female; Fu | 1975 |
Effect of pressor agents on blood pressure, plasma renin activity and plasma aldosterone concentration in essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hyperaldosteronism; | 1975 |
[Plasma aldosterone and plasma renin activity in patients with essential and renal hypertension under acute stimulation with saline depletion and acute suppression with saline infusion].
Topics: Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Female; Furosemide; Glomerulonephritis; | 1975 |
Letter: Adrenal tumours and hypertension.
Topics: Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension | 1975 |
Therapy and prognosis of hypertension in chronic nephritis.
Topics: Adult; Aldosterone; Angiotensin II; Blood Volume; Catecholamines; Chronic Disease; Creatinine; Extra | 1975 |
Proceedings: Changes of plasma renin activity and plasma aldosterone by aging of spontaneously hypertensive rat, and their relationship with blood pressure.
Topics: Aging; Aldosterone; Animals; Disease Models, Animal; Hypertension; Rats; Renin | 1975 |
Deoxycorticosterone excretion in normal, hypertensive and hypokalaemic subjects.
Topics: Aldosterone; Animals; Bicarbonates; Blood Pressure; Cross Reactions; Desoxycorticosterone; Humans; H | 1975 |
[Spironolactone and thiabutazide in the treatment of essential hypertension (author's transl)].
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Body Weight; Butanes; Female; Furosemide; Huma | 1975 |
[Renin-angiotensin - aldosterone system in essential hypertension].
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Radioimmunoassay; Renin | 1975 |
Extensive hypertensive work-up: pro.
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Antihypertensive Agents; Attitude to Health; Epidemiolo | 1975 |
Response of plasma aldosterone to fludrocortisone in primary hyperaldosteronism and other forms of hypertension.
Topics: Adenocarcinoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Aldosterone; Desoxycorticost | 1975 |
[Liquorice syndrome].
Topics: Adult; Aldosterone; Female; Glycyrrhiza; Humans; Hypertension; Hypokalemia; Plants, Medicinal; Renin | 1975 |
[Hypertension and oral contraceptives. Own experiences].
Topics: Adult; Aldosterone; Contraceptives, Oral; Female; Humans; Hypertension; Middle Aged; Renin | 1975 |
Selection of patients and operative approach in primary aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; | 1975 |
Effects of unilateral nephrectomy in man on renin, aldosterone and volume/pressure relationships.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Kidney; Male; Nephrectomy; Pla | 1975 |
The classification and treatment of essential hypertension using the renin-sodium index for vasoconstriction-volume analysis.
Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; | 1975 |
Mineralocorticoid activity in patients in the early benign phase of essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Liver; Middle Aged; Progesterone; Renin | 1975 |
Adrenal steroidogenesis in "low renin" or hyporeninemic hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Biological Assa | 1975 |
[Clinical importance of the renin-angiotensin-aldosterone system in hypertension].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Renin | 1975 |
Hypertension, oedema, and suppressed renin aldosterone system due to unsupervised salt administration.
Topics: Aldosterone; Child, Preschool; Diarrhea, Infantile; Edema; Female; Glucose; Humans; Hypernatremia; H | 1975 |
Comparison between the effects of ST 600 and clonidine.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Volume; Cardiac Output; Clo | 1975 |
Oral contraceptive pill hypertension.
Topics: Adolescent; Adult; Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Body Weight; Contracep | 1975 |
[Effects of acebutolol on the renin-aldosterone system in essential arterial hypertension].
Topics: Acebutolol; Adolescent; Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Humans; Hyperte | 1975 |
[Renin-angiotensin-aldosterone system in hypertensive disease and arteriosclerotic myocardioslcerosis complicated by chronic circulatory insufficiency].
Topics: Aged; Aldosterone; Angiotensin II; Blood Circulation; Chronic Disease; Coronary Disease; Female; Hum | 1975 |
[Behavior of blood pressure during oral hormonal anticonception].
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Contraceptives | 1975 |
Water, sodium, potassium, and electrolyte balance.
Topics: Aged; Aldosterone; Child, Preschool; Diet; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Hype | 1975 |
[Diazoxide test in the diagnosis of arterial hypertension: modifications in the levels of renin and aldosterone in blood of patients with various restrains of the renal function].
Topics: Adolescent; Adult; Aldosterone; Diazoxide; Humans; Hyperaldosteronism; Hypertension; Kidney Diseases | 1975 |
[Changes in the corticosteroids and their alpha-ketol metabolites in the urine of hypertension patients treated with metopirons].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aldosterone; Circadian Rhythm; Cortodoxone; Desoxycortic | 1975 |
Hypertension as a disease of modern society.
Topics: Adaptation, Psychological; Aldosterone; Blood Pressure; Diet; Humans; Hypertension; Life Style; Soci | 1975 |
[Interference of canrenoate potassium with plasma renin activity. Note I. Effects of canrenoate potassiumon plasma renin activity in patients with essential hypertension].
Topics: Adult; Aged; Aldosterone; Canrenoic Acid; Electrolytes; Female; Humans; Hypertension; Male; Middle A | 1975 |
[Renin and aldosterone].
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Juxtaglomerular Apparatus; Li | 1975 |
Stimulated renin: a screening test for hypertension.
Topics: Adult; Aged; Aldosterone; Diagnosis, Differential; Evaluation Studies as Topic; Female; Furosemide; | 1975 |
[Clinical and etiological studies of glucocorticoid-reactive hypertension].
Topics: Adolescent; Adult; Aldosterone; Female; Glucocorticoids; Humans; Hypertension; Male; Middle Aged; Po | 1975 |
[Hypertension in the aged. (4) Renal and hormonal factors].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Catecholamines; Desoxycorticosterone; Hormones; Humans; Hy | 1975 |
[A reduced aldosterone response to infused angiotensin II in low renin essential hypertension (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1975 |
[Experimental studies on the determination of serum aldosterone by direct extraction using aldosterone-radioimmunoassay-kit (CIS) but without chromatography].
Topics: Adrenal Gland Diseases; Aldosterone; Humans; Hypertension; Radioimmunoassay | 1975 |
[Functional state and reactivity of the adrenal cortex in rats with hereditarily conditioned hypertension].
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Animals; Blood Pressure; Human | 1975 |
[Physiopathology and clinical aspects of primary hyperaldosteronism].
Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Proteinuri | 1975 |
Low renin essential hypertension in a child.
Topics: Aldosterone; Child; Circadian Rhythm; Dexamethasone; Humans; Hydrochlorothiazide; Hydrocortisone; Hy | 1976 |
Location of aldosterone-producing adenomas with 131I-19-iodocholesterol.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cholesterol; Humans; Hyperaldosteronism; Hypertension | 1976 |
Editorial: Solving the adrenal lesion(s) of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cholesterol; Humans; Hyperaldosteronism; Hypertension | 1976 |
Mineralocorticoid secretion in essential hypertension with normal and low plasma renin activity.
Topics: 18-Hydroxycorticosterone; Adult; Aldosterone; Corticosterone; Desoxycorticosterone; Humans; Hyperten | 1976 |
The effect of dietary sodium chloride on blood pressure, body fluids, electrolytes, renal function, and serum lipids of normotensive man.
Topics: Adult; Aldosterone; Blood Pressure; Body Fluids; Body Weight; Cholesterol; Diet, Sodium-Restricted; | 1976 |
[Diurnal variation in the urinary excretion of vanilmandelic acid and aldosterone in normal and hypertensive persons (author's transl)].
Topics: Adult; Aldosterone; Circadian Rhythm; Creatinine; Female; Humans; Hyperaldosteronism; Hypertension; | 1976 |
[Principle and range of application of radioimmunoassay. (V). The renin-angiontensin-aldosterone system].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Juxtaglomerular Apparatus; Radioimmunoassay; Reni | 1976 |
Renin-angiotensin-aldosterone system in experimental renal hypertension in the rabbit.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Corticost | 1976 |
Suppression of the renin-aldosterone system in mild essential hypertension.
Topics: Adult; Aldosterone; Extracellular Space; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Po | 1976 |
Aldosterone metabolic clearance is normal in low-renin essential hypertension.
Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Body Surface Area; Female; Hum | 1976 |
[Primary aldosteronism].
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Aldosterone; Antihyp | 1976 |
Enflurane anaesthesia for removal of aldosterone producing adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Anesthesia, Inhalation; Blood Pressure; Enflur | 1976 |
Relation between plasma renin activity, angiotensin, and aldosterone and blood pressure in mild untreated hypertension.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Arteries; Blood Pressure; Diet; Female; Humans; Hype | 1976 |
Urine aldosterone radioimmunoassay: validation of a method without chromatography.
Topics: Adrenal Gland Diseases; Aldosterone; Chromatography, Paper; Cushing Syndrome; Humans; Hyperaldostero | 1976 |
Triamterene-induced changes in aldosterone and renin values in essential hypertension. Evidence of a role for aldosterone in preventing blood pressure reduction.
Topics: Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Renin; Sodi | 1976 |
Nilvadipine in hypertension with renal dysfunction.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Creatinine; Female; Heart Rate; H | 1992 |
[Liddle syndrome (or pseudo-hyperaldosteronism). Long-term development and erythrocyte potassium flow study in 4 cases].
Topics: Aldosterone; Alkalosis; Cell Membrane Permeability; Child; Child, Preschool; Erythrocyte Membrane; F | 1992 |
Subdiaphragmatic vagotomy in rats induces systemic hypertension and sodium retention.
Topics: Aldosterone; Animals; Corticosterone; Female; Hypertension; Potassium; Rats; Rats, Sprague-Dawley; R | 1992 |
Adrenal renin is released into the circulation of the hypertensive transgenic rat TGR (mRen-2)27.
Topics: Adrenal Glands; Aldosterone; Animals; Cells, Cultured; Dexamethasone; Disease Models, Animal; Hypert | 1992 |
Twenty-four year spironolactone therapy in an aged patient with aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aged; Aldosterone; Fe | 1992 |
Mineralocorticoids and mineralocorticoid receptors in mononuclear leukocytes in patients with pregnancy-induced hypertension.
Topics: 18-Hydroxycorticosterone; Aldosterone; Female; Humans; Hypertension; Leukocytes, Mononuclear; Minera | 1992 |
Suppression of the renin-angiotensin-aldosterone axis with erythropoietin therapy by a negative feedback loop.
Topics: Adult; Aged; Aldosterone; Anemia; Erythropoietin; Feedback; Hemoglobins; Humans; Hypertension; Middl | 1992 |
The role of the adrenal gland in hypertensive transgenic rat TGR(mREN2)27.
Topics: 18-Hydroxycorticosterone; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Animals | 1992 |
[Adrenal corticosteroid and disease models of hypertension].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Desoxycorticoster | 1992 |
[Effect of antihypertensive therapy with captopril on gluco- and mineralocorticoid receptors of peripheral blood lymphocytes in hypertensive patients of various age].
Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Captopril; Female; Humans; Hypertension; Lymphoc | 1992 |
The role of atrial natriuretic peptide in natriuresis of fasting.
Topics: Adolescent; Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Fasting; Female; Humans; Hypertensi | 1992 |
Plasma 19-hydroxy-androstenedione (19-OH-A) in essential hypertension.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Androstenedione; Catecholamines; Exercise Test; Hum | 1992 |
Do opioid receptors participate in the regulation of atrial natriuretic peptide (ANP) secretion in hypertensive patients?
Topics: Adult; Aldosterone; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; Female; Humans; | 1992 |
[The interrelationship between humoral factors and the indices of left ventricular myocardial hypertrophy in hypertension].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Hemodynamics; Humans; Hydrocortisone; Hyper | 1992 |
Kallikrein-kinin,enkephalin, renin-aldosterone and catecholamine systems in the vanadate (as vanadyl)-induced arterial hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Bradykinin; Bucladesine; Catecholamines; Diastole; Enkephalins | 1992 |
Circadian rhythm of calcitonin gene-related peptide in uncomplicated essential hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Calcitonin Gene-Related Peptide; Case | 1992 |
Acute effects of angiotensin-converting enzyme inhibitor on erythrocyte sodium ion transport in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Carrier Proteins; Cell Membrane Permeability; Erythro | 1992 |
[The correlation of humoral factors with the indices of the phasic structure of the left ventricular cardiac cycle in hypertension patients].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Chronic Disease; Combined Modality Therapy; Female; | 1992 |
[The behavior of serum angiotensin-converting enzyme in normotensive subjects, in subjects with essential hypertension and in subjects with primary hyperaldosteronism on the orthostatic test].
Topics: Adult; Aldosterone; Bed Rest; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; P | 1992 |
Effects of dietary magnesium supplementation on diurnal variations of blood pressure and plasma Na+, K(+)-ATPase activity in essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Circadian Rhythm; Female; Humans; Hypertension; Magnesium; | 1992 |
Effect of manidipine on cardiac hypertrophy and coronary circulation in DOCA/salt hypertensive rats.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Coronary Circulation; C | 1992 |
Reduction of left ventricular hypertrophy after longterm antihypertensive treatment with doxazosin.
Topics: Adrenergic alpha-Antagonists; Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Cardiomeg | 1992 |
Primary aldosteronism: hypertension with a genetic basis.
Topics: Adrenocorticotropic Hormone; Aldosterone; Humans; Hyperaldosteronism; Hypertension | 1992 |
[Effect of nifedipine treatment on the renin-aldosterone system and secretion of cortisol and growth hormone in patients with essential hypertension].
Topics: Adult; Aldosterone; Female; Growth Hormone; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; | 1991 |
Hemodynamic and endocrine changes associated with hypotensive action of amosulalol in essential hypertension.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Cardiac Output; Ethanolamines; Female; | 1992 |
Atrial natriuretic factor in essential hypertension: echocardiographic and humoral correlates.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Echocardiography; Female; Humans; Hypertension; Male; | 1992 |
Effect of a reduction in sodium intake on cold-induced elevation of blood pressure in the rat.
Topics: Acclimatization; Aldosterone; Animals; Blood Pressure; Body Weight; Cardiomegaly; Cold Temperature; | 1992 |
[Diurnal variation of blood pressure in salt-responder].
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Circadian Rhythm; Female; Heart Rate; | 1992 |
Atrial and brain natriuretic peptides: secretion during exercise in patients with essential hypertension and modulation by acute angiotensin-converting enzyme inhibition.
Topics: Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood Pressu | 1992 |
The influence of age on renal function and renin and aldosterone responses to sodium-volume expansion and contraction in normotensive and mildly hypertensive humans.
Topics: Adolescent; Adult; Aging; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Creatine; Cross-Se | 1992 |
Zonal distribution and regulation of adrenal renin in a transgenic model of hypertension in the rat.
Topics: Adrenal Glands; Aldosterone; Animals; Animals, Genetically Modified; Cells, Cultured; Hypertension; | 1992 |
Altered secretion of corticosteroids and prolactin in adrenal regeneration hypertensive rats.
Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Dopamine; Electrolytes; Hypertension; Male; Mi | 1992 |
Abnormal norepinephrine and aldosterone responses to upright posture in nonmodulating hypertension.
Topics: Adult; Aldosterone; Analysis of Variance; Animals; Catecholamines; Female; Humans; Hypertension; In | 1992 |
Elevation of plasma atrial natriuretic peptide occurs during adrenaline infusion in hypertensive but not normotensive subjects.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Epinephrine; Female; Heart Rate; Huma | 1992 |
Response of plasma renin-angiotensin system to a single captopril administration in patients receiving long-term treatment with captopril.
Topics: Aldosterone; Angiotensin II; Angiotensin III; Blood Pressure; Captopril; Drug Tolerance; Female; Hea | 1992 |
[The dynamics of the concentration of atrial natriuretic factor depending on changes in the arterial pressure level in patients with arterial hypertension].
Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Captopril; Chronic Disease; Humans; Hydrochl | 1992 |
[The morphofunctional parallels in arterial hypertension in patients with chronic glomerulonephritis].
Topics: Aldosterone; Biopsy; Chronic Disease; Glomerulonephritis; Glomerulonephritis, Membranoproliferative; | 1992 |
[The morphofunctional parallels in arterial hypertension in patients with chronic glomerulonephritis].
Topics: Adult; Aldosterone; Chronic Disease; Glomerulonephritis; Glomerulonephritis, Membranoproliferative; | 1992 |
Non-modulation as an intermediate phenotype in essential hypertension.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; | 1992 |
Renin-angiotensin-aldosterone system and thromboxane A2/prostacyclin in normotensive and hypertensive black Zimbabweans.
Topics: Adult; Aldosterone; Black People; Epoprostenol; Evaluation Studies as Topic; Humans; Hypertension; M | 1992 |
[Functional state of the adrenals in various forms of arterial hypertension].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Cushing Syndrome; Huma | 1992 |
[Changes in the humoral systems in juvenile arterial hypertension and their correction by using nifedipine and anaprilin].
Topics: Adolescent; Aldosterone; Angiotensin II; Blood Pressure; Drug Evaluation; Humans; Hypertension; Nife | 1992 |
23Na NMR evaluation of human erythrocytes Na+/K+/CL-cotransport. A study in elderly hypertensives.
Topics: Aged; Aldosterone; Blood Pressure; Carrier Proteins; Cholesterol; Creatinine; Erythrocytes; Humans; | 1992 |
[Cardiac and renal sodium-modulating hormones in juvenile arterial hypertension. The physiopathological aspects and therapeutic results of a trial at the Policlinico Militare Celio in Rome].
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Heart; Hospitals, Military; Humans; H | 1992 |
Renin and aldosterone levels and hypertension following envenomation in humans by the yellow scorpion Leiurus quinquestriatus.
Topics: Adult; Aldosterone; Animals; Child; Child, Preschool; Humans; Hypertension; Infant; Middle Aged; Ren | 1992 |
[Dopamine mechanisms in salt-responsive hypertension].
Topics: Aldosterone; Catecholamines; Dopamine; Humans; Hypertension; Renin; Sodium, Dietary | 1992 |
[Pathophysiology of normotensive subjects with a family history of hypertension].
Topics: Adult; Aldosterone; Blood Pressure; Cell Membrane; Electrolytes; Humans; Hypertension; Kidney; Middl | 1992 |
[Disease models of steroid-induced hypertension].
Topics: Aldosterone; Animals; Corticosterone; Cushing Syndrome; Desoxycorticosterone; Dexamethasone; Disease | 1992 |
Adrenal and circulating renin-angiotensin system in stroke-prone hypertensive rats.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Cerebrovascular Disorders; Concanavalin A; Enz | 1992 |
Concurrence of primary aldosteronism and renal artery stenosis.
Topics: Adrenal Cortex; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renal Arte | 1992 |
Renin-aldosterone relationships in pregnancy-induced hypertension.
Topics: Aldosterone; Female; Humans; Hypertension; Osmolar Concentration; Pregnancy; Pregnancy Complications | 1992 |
The hypertensinogenic activity of 18,19-dihydroxycorticosterone in adrenalectomized rats.
Topics: 18-Hydroxycorticosterone; Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Blood Pressure; Drug | 1992 |
Weight reduction decreases the circulating concentration of the N-terminus of the ANF prohormone.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Diet, Reducing; Female; Humans; | 1992 |
Importance of atrial natriuretic hormone in an exaggerated natriuresis during acute sodium load in primary aldosteronism.
Topics: Aldosterone; Atrial Natriuretic Factor; Dopamine; Glomerular Filtration Rate; Humans; Hyperaldostero | 1992 |
Endocrine sodium and volume regulation in familial hyperkalemia with hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Family; Female; Humans; Hydrochloroth | 1992 |
[Study on uric acid metabolism in patients with primary aldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Female; Humans; Hyperaldosteron | 1992 |
Hypertension during reduction of long-term steroid therapy in young subjects with asthma.
Topics: Adolescent; Adrenal Cortex Hormones; Aldosterone; Asthma; Child; Female; Follow-Up Studies; Humans; | 1992 |
Determination of urinary 18-hydroxycortisol in the diagnosis of primary aldosteronism.
Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Diagnosis, | 1992 |
Aldosterone metabolism in the isolated perfused liver of R and S hypertension-prone Dahl rats.
Topics: Aldosterone; Animals; Bile; Chromatography, High Pressure Liquid; Hypertension; In Vitro Techniques; | 1992 |
Increased systemic and renal vascular sensitivity to angiotensin II in normotensive men with positive family histories of hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Glomerular Filtration Rate; Heart R | 1992 |
Metabolic cardiovascular risk factors and the renin-aldosterone system in essential hypertension.
Topics: Adult; Aldosterone; Body Mass Index; Cardiovascular Diseases; Cholesterol, HDL; Creatine; Female; Gl | 1992 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 24-1992. A 52-year-old man with hypertension, hypokalemia, and an adrenal mass.
Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemi | 1992 |
Vascular responsiveness in rats resistant to aldosterone-salt hypertension.
Topics: Aldosterone; Animals; Blood Vessels; Carotid Arteries; Disease Susceptibility; Hypertension; Male; R | 1992 |
Adrenocorticosteroid excretion in salt-sensitive and salt-resistant spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Chromatography, Thin Layer; Corticosterone; Desoxycorticostero | 1992 |
First dose hypotension after captopril; can it be predicted? A study of 240 patients.
Topics: Aldosterone; Captopril; Diastole; Forecasting; Humans; Hypertension; Hypotension; Prevalence; Prospe | 1992 |
Enalapril versus combined enalapril and nadolol treatment: effects on blood pressure, heart rate, humoral variables, and plasma potassium at rest and during exercise in hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Combined Modality Therapy; Enalapril; Female; Heart Rate; Hemody | 1992 |
[Does the captopril test improve the diagnosis of primary hyperaldosteronism?].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Pressure; Captopril; Diagnosis, Differen | 1992 |
Diagnostic approach to patients with primary hyperaldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertens | 1991 |
Sodium metabolism in offspring of hypertensive parents.
Topics: Adolescent; Adult; Aldosterone; Child; Erythrocytes; Female; Humans; Hypertension; Male; Reference V | 1991 |
[The significance of atrial natriuretic polypeptide in the cause of essential hypertension].
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Cyclic GMP; Dopamin | 1991 |
Plasma and tissue kallikrein-kinin systems during acute administration of frusemide in normotensive and hypertensive humans.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Dinoprostone; Electrolytes; Female | 1991 |
Influence of betaxolol on renal function and atrial natriuretic peptide in essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Atrial Natriuretic Factor; Betaxolol; Exercise Test; Female; Furosem | 1991 |
Atrial natriuretic peptide in patients with essential hypertension. Hemodynamic, renal, and hormonal responses.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cardiac Output; Cyclic GMP; Glomerula | 1991 |
Altered phospholipase activities related to alpha 1-adrenergic receptor supersensitivity of aortas from aldosterone-salt hypertensive rats.
Topics: Aldosterone; Animals; Aorta; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nore | 1991 |
Distinct plasma atrial natriuretic factor, renin and aldosterone responses to prolonged high-salt intake in hypertensive and normotensive rats.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Guanylate Cyclase; Homeostasis; Hypertension; Male; | 1991 |
Remodeling of the rat right and left ventricles in experimental hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Cardiomegaly; Collagen; Fibrosis; Heart Ventricles; Hemodynami | 1990 |
Body sodium in normal subjects predisposed to hypertension.
Topics: Aldosterone; Blood Pressure; Body Weight; Creatinine; Diet; Heart Rate; Humans; Hypertension; Male; | 1990 |
The diurnal rhythm of plasma potassium: relationship to diuretic therapy.
Topics: Adult; Aldosterone; Amiloride; Animals; Blood Pressure; Circadian Rhythm; Cricetinae; Diuretics; Ele | 1991 |
Regression of cardiovascular structural changes after long-term antihypertensive treatment with the calcium antagonist nitrendipine.
Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Echocardiography; Female; Heart Rate; Hemodynami | 1991 |
Renin-angiotensin-aldosterone system in normal and hypertensive pregnancy. Response to postural stimuli.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Posture; Pregnancy; Pr | 1992 |
Dipyridamole decreases circulating renin-angiotensin system activity in hypertensive patients.
Topics: Adenosine; Administration, Oral; Adult; Aldosterone; Blood Pressure; Creatine; Dipyridamole; Female; | 1992 |
Acute effect of erythropoietin on plasma renin activity and aldosterone levels in end-stage renal disease.
Topics: Aldosterone; Blood Pressure; Erythropoietin; Humans; Hypertension; Kidney Failure, Chronic; Renin; V | 1992 |
Effects of angiotensin subtype 1 and subtype 2 receptor antagonists in normotensive versus hypertensive rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Comp | 1991 |
[The somatotype, blood hormone content and the threshold of taste sensitivity to table salt in young people with arterial hypertension].
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Growth Hormone; Hormones; Humans; Hypertension; Insu | 1991 |
[The specificity of the hypotensive effect of calcium antagonists in hypertension].
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Calcium; Calcium Channel Blockers | 1991 |
Sustained effects of biofeedback-assisted relaxation therapy in essential hypertension.
Topics: Adult; Aldosterone; Analysis of Variance; Anxiety; Biofeedback, Psychology; Blood Pressure; Humans; | 1991 |
Effect of chronic treatment with clonidine and spironolactone on cold-induced elevation of blood pressure.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Clonidine; Cold Temperature; Drin | 1991 |
Daily profiles of aldosterone levels during normal, high and low sodium intake in patients with essential hypertension.
Topics: Adult; Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Periodicity; Renin; Sodium, Dieta | 1991 |
Effects of cicletanine on vasoactive systems in conscious sinoaortic-denervated dogs.
Topics: Aldosterone; Amino Acid Sequence; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; C | 1991 |
Influence of nonhemodynamic factors on the microcirculation in moderate arterial essential hypertension.
Topics: Aldosterone; Blood Pressure; Hemodynamics; Humans; Hypertension; Microcirculation; Middle Aged; Nore | 1991 |
Hyperfiltration and calcium metabolism in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Calcitriol; Calcium; Creatine; Female; Glomerular Filtration Rat | 1991 |
[Aldosteroma (Conn's syndrome)].
Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aldosterone; Diagnosis, Differential; Fema | 1991 |
Arterial structural changes and pressor responsiveness to noradrenaline.
Topics: Adult; Aldosterone; Arteries; Blood Pressure; Forearm; Humans; Hypertension; Middle Aged; Norepineph | 1991 |
Plasma endothelin-1,2 levels in mild and severe hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Endothelins; Humans; Hypertension; Middle Aged; Renin | 1991 |
Time-course of changes in intracellular cations and blood pressure with salt loading in patients with essential hypertension.
Topics: Aldosterone; Blood Pressure; Calcium; Cations; Erythrocytes; Female; Hematocrit; Humans; Hypertensio | 1991 |
[The level of plasma renin and plasma aldosterone activity in normotensive women and in pregnancy-induced arterial hypertension in a group of women from Cameroon].
Topics: Adult; Aldosterone; Blood Pressure; Cameroon; Female; Humans; Hypertension; Pregnancy; Pregnancy Com | 1991 |
Elevation of plasma endothelin associated with systemic hypertension in humans following orthotopic liver transplantation.
Topics: Aldosterone; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Endothelins; Female; Humans; Hyp | 1991 |
Abnormal hormonal and renal responses to saline load in hypertensive patients with parental history of cardiovascular accidents.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cerebrovascular Disorders; Family Hea | 1991 |
[Endothelin in arterial hypertension].
Topics: Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Endothelins; Heart Failure; Humans; Hyperten | 1991 |
[Atrial natriuretic factor in patients with hypertension].
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Hemodynamics; Humans; Hypertension; Natriuresis; Reni | 1991 |
[Relation between traditional Chinese medicine differential types and plasma levels of renin, angiotension II, aldosterone, atrial natriuretic factor in patients with essential hypertension].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Female; Humans; Hypertension; M | 1991 |
Dissociation of plasma atrial natriuretic peptide responses to upright posture and furosemide administration in patients with normal-, low renin essential hypertension and primary aldosteronism.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Furosemide; Humans; Hyperaldosteronism; Hypertension; | 1991 |
Influence of the arterial blood pressure and nonhemodynamic factors on left ventricular hypertrophy in moderate essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Determination; Cardiomegaly; Epinephrine; Female; | 1991 |
Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Biomarkers; Blood Pres | 1991 |
Plasma concentrations of atrial natriuretic hormone in acromegaly: relationship to hypertension.
Topics: Acromegaly; Adult; Aldosterone; Analysis of Variance; Atrial Natriuretic Factor; Blood Pressure; Fem | 1991 |
Plasma atrial natriuretic peptide and its relation to the renin-angiotensin-aldosterone system in patients with chronic renal failure.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Humans; Hypertension; Kidney Failure, | 1991 |
Calcium metabolism in elderly hypertensive patients: possible participation of exaggerated sodium, calcium and phosphate excretion.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Calcitriol; | 1991 |
Therapeutic response may be predicted by some clinical parameters in essential hypertensive patients.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Blood Pressure; Cardiomegaly; | 1991 |
Atrial natriuretic peptide and plasma volume in pregnancy-induced hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Volume; Capillary Permeability; Female; Humans; | 1991 |
The syndrome of hypertension and hyperkalemia with normal GFR (Gordon's syndrome): is there increased proximal sodium reabsorption?
Topics: Absorption; Adult; Aldosterone; Atrial Natriuretic Factor; Female; Glomerular Filtration Rate; Human | 1991 |
Relationship between parathyroid hormone and left ventricular mass in moderate essential hypertension.
Topics: Aldosterone; Blood Pressure; Cardiomegaly; Epinephrine; Female; Humans; Hypertension; Male; Middle A | 1991 |
Impairment of atrial natriuretic factor response to acute saline load in hypertensives with family history of cardiovascular accidents.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Cerebrovascular Disorders; Female; Humans; Hypertensi | 1991 |
Plasma sodium-potassium ATPase inhibition activity in low- and normal-renin hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Longitudinal Studies; Male; Norepi | 1991 |
Resting and volume-stimulated circulating atrial natriuretic peptide in young normotensive men with positive family histories of hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Body Mass Index; Central Venous Press | 1991 |
Platelet-free calcium and vascular calcium uptake in ethanol-induced hypertensive rats.
Topics: Administration, Oral; Aldosterone; Animals; Aorta; Blood Platelets; Blood Pressure; Body Weight; Cal | 1991 |
[Corticoid secretion and patho-histological changes in the adrenal glands in hypertension].
Topics: 11-Hydroxycorticosteroids; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Atrophy; Humans; Hydro | 1991 |
[The renin-angiotensin-aldosterone system and arterial hypertension in patients with rheumatoid arthritis].
Topics: Adult; Aldosterone; Arthritis, Rheumatoid; Blood Pressure; Female; Humans; Hypertension; Middle Aged | 1991 |
Angiotensin II mediates hyperadrenergic activity evoked by sodium restriction in essential hypertension.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Diet, Sodium-Restrict | 1991 |
[Arterial hypertension secondary to an aldosterone-producing adenoma (APA)].
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension; Male; Middle Aged | 1991 |
Effect of inhibition of converting enzyme on renal hemodynamics and sodium management in polycystic kidney disease.
Topics: Adult; Aldosterone; Blood Pressure; Enalapril; Erythrocytes; Female; Genes, Dominant; Glomerular Fil | 1991 |
Licorice-induced hypermineralocorticoidism.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aged; Aldosterone; Desoxycorticosterone; Foodborne Diseases; | 1991 |
Effect of chronic dietary treatment with L-tryptophan on the development of cold-induced hypertension in rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Catecholamines; Cold Temperature; Diet; Hypert | 1991 |
Historical reflections on hypertension.
Topics: Aldosterone; Auscultation; Blood Pressure Determination; Heart Sounds; History, 18th Century; Histor | 1991 |
Sexual function and neuropeptide Y levels in selected brain regions in male spontaneously hypertensive rats.
Topics: Aldosterone; Analysis of Variance; Animals; Blood Pressure; Body Weight; Brain Chemistry; Copulation | 1991 |
Angiotensin-converting enzyme inhibitor and anemia in a patient undergoing hemodialysis.
Topics: Aldosterone; Anemia; Blood Pressure; Enalapril; Erythropoietin; Hematocrit; Humans; Hypertension; Ki | 1991 |
Systemic and renal effects of a new angiotensin converting enzyme inhibitor, benazepril, in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Drug Evaluation; Electro | 1990 |
Infradian, notably circannual, cardiovascular variation gauging effect of intrauterine exposure to beta-adrenergic agonists.
Topics: Adrenergic beta-Agonists; Aldosterone; Blood Pressure; Cardiovascular Physiological Phenomena; Cardi | 1990 |
Captopril attenuates reflex adrenergic response in essential hypertension.
Topics: Administration, Oral; Adult; Aldosterone; Blood Pressure; Captopril; Female; Hemodynamics; Humans; H | 1991 |
Effect of a new mineralocorticoid antagonist mespirenone on aldosterone-induced hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Hypertension; Male; Mineralocorticoid Receptor An | 1991 |
Temporal relationship between the decrease in arterial pressure and sodium retention in conscious spontaneously hypertensive rats with carbon tetrachloride-induced cirrhosis.
Topics: Aldosterone; Animals; Blood Pressure; Carbon Tetrachloride; Creatinine; Hypertension; Liver Cirrhosi | 1991 |
Renal hemodynamics and the renin-angiotensin-aldosterone system in normotensive subjects with hypertensive and normotensive parents.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Child; Female; Hemodynamics; Humans; | 1991 |
Feasibility of outpatient electrolyte balance studies.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Creatinine; Feasibility Studies; Female; Humans; Hypertensi | 1991 |
Effect of high calcium diet on the development of high blood pressure in intact spontaneously hypertensive rats and in adrenalectomized spontaneously hypertensive rats treated with aldosterone.
Topics: Adrenalectomy; Aldosterone; Animals; Body Weight; Calcium; Diet; Hypertension; Male; Rats; Rats, Inb | 1991 |
Antihypertensive effects of an aromatase inhibitor in inbred salt-sensitive rats.
Topics: Aldosterone; Androstenedione; Animals; Antihypertensive Agents; Aromatase Inhibitors; Cortisone; Des | 1991 |
[The correlation of the indices of humoral immunity and of the activity of the renin-angiotensin-aldosterone system in hypertensive patients].
Topics: Adult; Aldosterone; Angiotensin II; Antibody Formation; Disease Susceptibility; Humans; Hypertension | 1991 |
Increased production of angiotensin II in the adrenal gland of stroke-prone spontaneously hypertensive rats with malignant hypertension.
Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin I; Angiotensin II; Animals; Cerebrovascular Disorder | 1991 |
Inappropriate elevation of the aldosterone/plasma renin activity ratio in hypertensive patients with increases of 11-deoxycorticosterone and 18-hydroxy-11-deoxycorticosterone: a subtype of essential hypertension?
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Glands; Adrenocortical Hyperfunction; Adult; Aged; Aldostero | 1991 |
Effects of slow-release nifedipine on water-sodium, uric acid, and calcium metabolism, and on aldosterone secretion in patients with essential hypertension.
Topics: Aldosterone; Angiotensin II; Calcium; Delayed-Action Preparations; Humans; Hypertension; Nifedipine; | 1990 |
Hyperkalemia and hypertension: is this a "chloride-shunt" disorder?
Topics: Acidosis; Adolescent; Aldosterone; Chlorides; Diuretics; Female; Humans; Hyperkalemia; Hypertension; | 1990 |
Preventive effect of angiotensin I on weight reduction in the adrenal glands of DOCA/salt hypertensive rats.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Animals; Blood Pressure; Body Weight; Corticosterone; De | 1990 |
[Circadian rhythm of the renin-angiotensin-aldosterone system in the normal state and in pathology].
Topics: Aldosterone; Angiotensin III; Circadian Rhythm; Humans; Hyperaldosteronism; Hypertension; Reference | 1990 |
[Diurnal fluctuations of plasma renin activity and aldosterone level in patients with arterial hypertension].
Topics: Aldosterone; Blood Pressure; Chronic Disease; Circadian Rhythm; Humans; Hypertension; Hypertension, | 1990 |
Long-term medical management of aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Benzothiadiazines; Combined Modality Therapy; Diureti | 1990 |
[The effect of clonidine on humoral factors in patients with arterial hypertension].
Topics: Adrenal Gland Neoplasms; Aldosterone; Atrial Natriuretic Factor; Catecholamines; Clonidine; Diagnosi | 1990 |
Plasma atrial natriuretic factor levels during normal pregnancy and pregnancy complicated by diabetes mellitus and hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Female; Humans; Hypertension; Pregnancy; Pregnancy Co | 1990 |
Vasoactive humoral systems and sodium transport in erythrocytes of normotensive offsprings of essential hypertensive subjects.
Topics: Adult; Aldosterone; Biological Transport; Dinoprost; Erythrocytes; Furosemide; Humans; Hypertension; | 1990 |
Pattern of peripheral venous response to volume expansion in borderline systemic hypertension.
Topics: Adolescent; Adult; Aldosterone; ATPase Inhibitory Protein; Atrial Natriuretic Factor; Female; Forear | 1990 |
Plasma atrial natriuretic peptide in young normotensive subjects with a family history of hypertension and in young hypertensive patients.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure Determination; Evaluation Studies as T | 1990 |
Long term reduction in sodium balance: possible additional mechanism whereby nifedipine lowers blood pressure.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Female; Humans; Hy | 1990 |
[Mutual interaction of the renin-angiotensin system and the atrial natriuretic factor in the renal response to acute volume loading].
Topics: Aldosterone; Ascites; Atrial Natriuretic Factor; Extracellular Space; Humans; Hypertension; Kidney; | 1990 |
Flight influence on the plasma level of renin-angiotensin-aldosterone system and atrial natriuretic peptide.
Topics: Adult; Aerospace Medicine; Aldosterone; Angiotensin I; Angiotensin II; Atrial Natriuretic Factor; Hu | 1990 |
Atrial natriuretic peptide in normal and low renin essential hypertension.
Topics: Aldosterone; Atrial Natriuretic Factor; Furosemide; Humans; Hypertension; Posture; Renin; Renin-Angi | 1990 |
[Captopril and hypertensive cardiopathy : therapeutic effects and hormonal changes].
Topics: Aged; Aldosterone; Atrial Natriuretic Factor; Captopril; Female; Heart Failure; Humans; Hypertension | 1990 |
New aspects of mineralocorticoid hypertension.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenal Glands; Aldosterone; Atrial Natri | 1990 |
Prolonged low dose infusion of atrial natriuretic factor in essential hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Electrolytes; Heart Rate; | 1990 |
Effects of aldosterone on intralymphocytic sodium and potassium in patients with essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Lymphocytes; Male; Mid | 1990 |
Circadian rhythms of atrial natriuretic peptide, renin, aldosterone, cortisol, blood pressure and heart rate in normal and hypertensive subjects.
Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Circadian Rhythm; Female; Heart Rate; Humans | 1990 |
[The significance of cGMP and dopamine receptor on the natriuretic and hypotensive activities of synthetic atrial natriuretic polypeptide in essential hypertension].
Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Dopamine Antagonists; Humans; Hy | 1990 |
[Effect of a beta 1-receptor blocker on the plasma level of atrial natriuretic peptide in patients with essential hypertension in the exercise test].
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Betaxolol; Blood Pressure; Cyclic GMP; Exercise Test; | 1990 |
[Diagnosis of adrenal gland tumors].
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Androsterone; Cushing Syndrome; Diagnosis, Differenti | 1990 |
Amiloride blocks the onset of ACTH-induced hypertension in the sheep.
Topics: Adrenocorticotropic Hormone; Aldosterone; Amiloride; Animals; Blood Pressure; Drug Administration Sc | 1990 |
Hemodynamic and humoral effects of chronic antihypertensive treatment with fenquizone: importance of aldosterone response.
Topics: Adult; Aldosterone; Blood Pressure; Chronic Disease; Diuretics; Female; Forearm; Heart Rate; Hemodyn | 1990 |
[Processing of clinical tests for the diagnosis of hypertension].
Topics: Aldosterone; Blood Urea Nitrogen; Diagnosis, Differential; Electrolytes; Hematologic Tests; Humans; | 1990 |
Biochemical correction in the syndrome of hypertension and hyperkalaemia by severe dietary salt restriction suggests renin-aldosterone suppression critical in pathophysiology.
Topics: Adult; Aldosterone; Angiotensin II; Animals; Diet, Sodium-Restricted; Family Health; Humans; Hyperka | 1990 |
Pharmacological evaluation of hydroxypropylcellulose-ethylcellulose microcapsules containing piretanide.
Topics: Administration, Oral; Aldosterone; Animals; Blood Pressure; Body Weight; Cellulose; Diuretics; Drug | 1990 |
Assessment of renin dependency of hypertension with a dipeptide renin inhibitor.
Topics: Adult; Aged; Aldosterone; Dipeptides; Dose-Response Relationship, Drug; Female; Humans; Hydrochlorot | 1990 |
Physiological and immunopathological consequences of active immunization of spontaneously hypertensive and normotensive rats against murine renin.
Topics: Aldosterone; Angiotensinogen; Animals; Homeostasis; Hypertension; Immunization; Kidney; Male; Mice; | 1990 |
Angiotensin-converting enzyme (ACE) inhibition. Therapeutic option for diabetic hypertensive patients.
Topics: Adult; Aldosterone; Diabetes Mellitus, Type 2; Enalapril; Female; Humans; Hypertension; Male; Middle | 1990 |
Beneficial effects of angiotensin-converting enzyme inhibitor on renal function and glucose homeostasis in diabetics with hypertension.
Topics: Aged; Aldosterone; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; | 1990 |
Relationship between plasma catecholamines and the renin-aldosterone system during exercise in normal and essential hypertensive subjects.
Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Exercise; Exercise Test; Humans; Hypertension; M | 1990 |
Acromegaly and hypertension: prevalence and relationship to the renin-angiotensin-aldosterone system.
Topics: Acromegaly; Aldosterone; Blood Pressure; Cross-Sectional Studies; Female; Germany, West; Growth Horm | 1990 |
The renin-angiotensin-aldosterone system and autosomal dominant polycystic kidney disease.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Protocols; Enalapril; Female; Humans; Hypertension; Mal | 1990 |
[The malignant hypertension syndrome: incontrovertible and questionable truths].
Topics: Aldosterone; Biopsy, Needle; Chronic Disease; Glomerulonephritis; Hemodynamics; Humans; Hydrocortiso | 1990 |
Alterations in aldosterone secretion and metabolism in low renin hypertension.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Posture; Renin | 1990 |
[Plasma mineralocorticoids--aldosterone and desoxycorticosterone-- in patients with"low-renin"arterial hypertension].
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Atrophy; Desoxycorticosterone; Humans; Hypera | 1990 |
Salt sensitivity in hypertensive rats with angiotensin II administration.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Hypertension; Male; Rats; Rats, Inbred Strains | 1990 |
Effects of renin inhibition in systemic hypertension.
Topics: Adult; Aldosterone; Dipeptides; Epoprostenol; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1990 |
Serum aldosterone response to metoclopramide in normal subjects and acromegalic patients.
Topics: Acromegaly; Adult; Aldosterone; Dopamine; Female; Humans; Hypertension; Injections, Intravenous; Mal | 1990 |
Effects of altered dietary sodium intake on hormonal profiles in salt-sensitive hypertensive rats.
Topics: Aldosterone; Animals; Cortisone; Desoxycorticosterone; Diet; Hydroxycorticosteroids; Hypertension; M | 1990 |
[Plasma renin activity and aldosterone in patients with essential hypertension].
Topics: Adolescent; Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1990 |
Calcium antagonists inhibit elevated potassium efflux from aorta of aldosterone-salt hypertensive rats.
Topics: Aldosterone; Animals; Aorta; Calcium; Calcium Channel Blockers; Diltiazem; Hypertension; In Vitro Te | 1990 |
Prostanoids and aldosterone-induced mild experimental hypertension in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Animals; Blood Pressure; Hypertension; Indomethacin; Male | 1990 |
Salt-sensitive blood pressure and exaggerated vascular reactivity in the hypertension of diabetes mellitus.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Diabetes Mellitus, Type 2; Diet, Sodium-Re | 1990 |
Intracerebroventricular infusion of RU28318 blocks aldosterone-salt hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Cerebral Ventricles; Hypertension; Infusions, Parenteral; Male | 1990 |
Elevated K turnover in mesenteric arteries from aldosterone-salt hypertensive rats.
Topics: Aldosterone; Animals; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Potassium; Rats; | 1990 |
ICV infusion of corticosterone antagonizes ICV-aldosterone hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Cerebral Ventricles; Corticosterone; Hypertension; Injections, | 1990 |
Effects of antimineralocorticoid RU 26752 on steroid-induced hypertension in rats.
Topics: Aldosterone; Animals; Blood Pressure; Hypertension; Male; Nephrectomy; Rats; Rats, Inbred Strains; R | 1990 |
Primary aldosteronism. Study of twenty-six operated cases.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Female; Foll | 1990 |
Effect of high calcium diet and nitrendipine on the development of high blood pressure in adrenalectomised spontaneously hypertensive rats treated with aldosterone.
Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Calcium, Dietary; Hypertension; Male; Nitrendip | 1990 |
A symposium: International update--the important role of aldosterone and aldosterone antagonism in cardiovascular medicine. Based on symposia held in Brussels, Belgium and Newport Beach, California.
Topics: Aldosterone; Heart Diseases; Humans; Hypertension; Mineralocorticoid Receptor Antagonists | 1990 |
Role of aldosterone in angiotensin II-induced hypertension in rats.
Topics: Aldosterone; Angiotensin II; Animals; Dose-Response Relationship, Drug; Hypertension; Infusions, Int | 1990 |
Dopamine and nonmodulating hypertension.
Topics: Adrenal Glands; Aldosterone; Blood Pressure; Diet; Dopamine; Humans; Hypertension; Metoclopramide; P | 1990 |
Localization of aldosterone-producing adenoma: venous sampling in primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Female; Humans; Hydrocortisone | 1990 |
The effect of chronic guanfacine administration on high plasma vasopressin levels in essential hypertension.
Topics: Aldosterone; Blood Pressure; Female; Guanfacine; Guanidines; Humans; Hypertension; Male; Middle Aged | 1990 |
Chronic effects of arotinolol (S-596) in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Aldosterone; Animals; Blood Pressure; Body Weight; Heart Rate; Hyperten | 1985 |
Aldosterone binding in isolated tubules. IV. Autoradiography along the nephron of the spontaneously hypertensive rat.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Autoradiography; Binding Sites; Female; Hyperte | 1985 |
Why use angiotensin converting enzyme inhibitors to lower blood pressure?
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhib | 1985 |
Ketanserin: a possible tool for studying the role of serotonin in hypertension.
Topics: Aldosterone; Blood Pressure; Female; Hemodynamics; Humans; Hypertension; Ketanserin; Male; Middle Ag | 1985 |
Calcium metabolism and the renin-aldosterone system in essential hypertension.
Topics: Aldosterone; Blood Pressure; Calcium; Calcium Channel Blockers; Humans; Hypertension; Magnesium; Par | 1985 |
Unusual association of hyperkalemia and hypertension.
Topics: Adult; Aldosterone; Bicarbonates; Erythrocytes; Female; Humans; Hyperkalemia; Hypertension; Ion Chan | 1986 |
Cellular sodium transport in arterial wall--summary of studies by digital computer simulation.
Topics: Aldosterone; Animals; Arteries; Biological Transport, Active; Computers; Extracellular Space; Hypert | 1986 |
Changes in the pathophysiologic profile of blood pressure determinants during short-term enalapril administration.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Dose-Response Relationship, Drug; | 1986 |
Borderline hypertension and sodium sensitivity.
Topics: Aldosterone; Blood Pressure; Cardiac Output; Electrocardiography; Humans; Hypertension; Microcircula | 1986 |
Effects of an angiotensin-converting enzyme (ACE) inhibitor, SA446, on tissue ACE activity in normotensive, spontaneously hypertensive, and renal hypertensive rats.
Topics: 3-Mercaptopropionic Acid; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypert | 1987 |
Antihypertensive effects and pharmacokinetics of single and consecutive administration of doxazosin in patients with mild to moderate essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Creatinine; Doxazosin; Electrolytes; Female; Hea | 1987 |
Autometrically and automatically monitored, iatrogenous, inhalant-decongestant-associated high blood pressure quantified by rhythmometry.
Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Determination; Circadian Rhythm; Fluprednisolone; | 1987 |
[Excess mineralocorticoid syndrome secondary to nasal sprays containing 9 alpha-fluoroprednisolone].
Topics: Aldosterone; Fluprednisolone; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Mineralocorticoi | 1987 |
Antihypertensive, enzymatic, and hormonal activity of cilazapril, a new angiotensin-converting enzyme inhibitor in patients with mild to moderate essential hypertension.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cilazapril; F | 1988 |
Nifedipine does not blunt the aldosterone and cardiovascular response to angiotensin II and potassium infusion in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Drug Interactions; Female; Heart Rate; Hem | 1988 |
Long-term effect of tiapamil in essential hypertension.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Electrocardiography; Female; Hear | 1988 |
Hormonal and renal responses to oral once-daily calcium entry blocker in normotensive and hypertensive persons.
Topics: Adult; Aldosterone; Angiotensin II; Calcium Channel Blockers; Dopamine; Epinephrine; Female; Hemodyn | 1988 |
Effects of different sodium intakes on the antihypertensive and renal effects of single oral doses of nifedipine in hypertensive patients.
Topics: Administration, Oral; Adult; Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Furosemide; | 1987 |
Vasoconstriction and hypersensitivity to vasoactive substances after acute volume expansion in dogs.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Volume; Cardiac Output; Dextr | 1988 |
Altered chloride transport in arteries from aldosterone salt-hypertensive rats.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo | 1988 |
Effects of ketanserin on peripheral vascular pressor mechanisms in essential hypertension.
Topics: Aldosterone; Blood Pressure; Extremities; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male | 1988 |
Loop diuretics combined with an ACE inhibitor for treatment of hypertension: a study with furosemide, piretanide, and ramipril in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Bridged | 1989 |
Aldosterone, catecholamines, and CK-BB as biochemical markers in hypertensive intracerebral hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Catecholamines; Cerebral Hemorrhage; Creatine Kinase; H | 1989 |
Effect of angiotensin converting-enzyme inhibition on potassium-mediated aldosterone secretion in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Pota | 1985 |
Abnormal glomerular and tubular function during angiotensin converting enzyme inhibition in renovascular hypertension evaluated by the lithium clearance method.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Glomerular Filtration Rate; H | 1989 |
Short-term monotherapy with the potassium channel activator BRL 34915 on endocrine sodium regulation in essential hypertension.
Topics: Administration, Oral; Adult; Aldosterone; Atrial Natriuretic Factor; Benzopyrans; Blood Pressure; Cr | 1989 |
Atrial natriuretic peptide and exaggerated natriuresis during acute hypertonic volume expansion in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Volume; D | 1989 |
[Atrial natriuretic factor: an epidemiological study. Preliminary results].
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Epidemiologic Methods; Humans; Hypert | 1989 |
[Humoral mechanisms in the pathogenesis of arterial hypertension with emphasis on the renin-angiotensin-aldosterone system and natriuretic substances].
Topics: Aldosterone; Atrial Natriuretic Factor; Humans; Hypertension; Natriuretic Agents; Renin-Angiotensin | 1989 |
Hypoxic modulation of systolic blood pressure and urinary sodium excretion in spontaneously hypertensive rats after carotid body denervation.
Topics: Aldosterone; Animals; Blood Gas Analysis; Blood Pressure; Body Weight; Carotid Body; Hydrogen-Ion Co | 1989 |
[Role of atrial natriuretic peptide in hypertension].
Topics: Aldosterone; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Depression, Chemical; Huma | 1989 |
Weight reduction decreases atrial natriuretic factor and blood pressure in obese patients.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Electrolytes; Female; Heart Rat | 1989 |
On the pathogenesis of arterial blood pressure elevation early in the course of diabetic nephropathy.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Atrial Natriuretic Factor; Diabetes Mellitus, Typ | 1989 |
Effects of cilazapril on renal function and hormones in hypertensive patients with renal disease.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cilazapril; Female; Gl | 1989 |
Central and peripheral effects of the peptide ANF on renal function and blood pressure in hypertensive rats.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Heart Rate; Hypertension; Infusions | 1989 |
ACTH effects on aldosterone, cortisol, and other steroids.
Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; AIDS-Related | 1989 |
Prolonged converting enzyme inhibition in non-modulating hypertension.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diet, Sodium- | 1989 |
The antihypertensive response to lisinopril: the effect of age in a predominantly black population.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Black | 1989 |
Chronobiological evidence for an uncoupling of the Na,K-ATPase to aldosterone in normal renin hypertension.
Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Erythrocyte Membrane; Female; Humans; Hypertension | 1989 |
Effect of dietary sodium on the Na-K ATPase inhibitor in patients with essential hypertension.
Topics: Aldosterone; ATPase Inhibitory Protein; Biological Transport; Blood Proteins; Body Weight; Erythrocy | 1989 |
An association between mineral metabolism and the renin-aldosterone system in human hypertension.
Topics: Adult; Aldosterone; Calcium; Cyclic AMP; Female; Humans; Hypertension; Magnesium; Male; Middle Aged; | 1989 |
Progesterone antagonizes development but not maintenance of ACTH-induced hypertension in sheep.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure; Female; Hypertension; Infusions, | 1989 |
Angiotensin-induced hypertension in the rat. Sympathetic nerve activity and prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Angiotensin II; Animals; Blood Pressure; Dinoprostone; Hy | 1989 |
Endogenous digoxin-like immunoreactive factor and digitalis-like factor associated with the hypertension of patients receiving multiple alkylating agents as part of autologous bone marrow transplantation.
Topics: Adult; Aldosterone; Alkylating Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Protein | 1989 |
Enhanced slow-pressor response to angiotensin II in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Captopril; Hypertension; Kidney; Muscle, Smoot | 1989 |
Aldosterone, kallikrein, kininase I and II in normal and hypertension complicated pregnancy.
Topics: Aldosterone; Carboxypeptidases; Female; Humans; Hypertension; Kallikreins; Lysine Carboxypeptidase; | 1989 |
Adrenocortical steroid requirements for initiation of ACTH-dependent hypertension in sheep.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Ani | 1989 |
Bopindolol: long-term effects on blood pressure, renal function, plasma renin activity, and plasma aldosterone in mild-to-moderate essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Pressure; Electrolytes; Female; Heart R | 1989 |
Hemodynamic and beta-adrenergic receptor adaptations during long-term beta-adrenoceptor blockade. Studies with acebutolol, atenolol, pindolol, and propranolol in hypertensive patients.
Topics: Adaptation, Physiological; Adrenergic beta-Antagonists; Adult; Aldosterone; Catecholamines; Hemodyna | 1989 |
The effect of triple drug therapy on renal function in patients with essential hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Aldosterone; Antihypertensive Agents; Atenolol; Betaxolol; Blood | 1989 |
Comparison of dopamine and fenoldopam effects on renal blood flow and prostacyclin excretion in normal and essential hypertensive subjects.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adult; Aged; Aldosterone; Blood Pressure | 1989 |
Effect of oral potassium on urinary kallikrein excretion in essential hypertension.
Topics: Administration, Oral; Adult; Aldosterone; Humans; Hypertension; Kallikreins; Middle Aged; Potassium; | 1989 |
[Crisis of arterial hypertension in patients with primary aldosteronism].
Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adult; Aldosterone; | 1989 |
[The renin-angiotensin-aldosterone system in hypertension of hypothalamic origin].
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Hypothalamic Diseases; Middle | 1989 |
Glucocorticoid receptors and dissociation constant (Kd) are decreased in mononuclear leukocytes of spontaneously hypertensive rats (SHR-SP) as compared to normotensive Wistar-Kyoto rats (WKY).
Topics: 18-Hydroxycorticosterone; Aldosterone; Animals; Corticosterone; Female; Hypertension; Kinetics; Mono | 1989 |
Regulation of cardiac output during aldosterone-induced hypertension.
Topics: Aldosterone; Animals; Blood Pressure Monitors; Cardiac Output; Dogs; Hemodynamics; Hypertension; Inf | 1989 |
Effects of nicardipine on blood pressure and renal function in elderly hypertensive patients with renal dysfunction.
Topics: Aged; Aldosterone; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Cholesterol; Creatinine; Elec | 1989 |
Blood pressure and serum calcium responses to altered sodium intake in high renin hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Calcium; Female; Humans; Hypertension; Male; Norepinephrine; Ren | 1989 |
Effect of transdermal clonidine on the endocrine responses to insulin-induced hypoglycemia in essential hypertension.
Topics: Administration, Cutaneous; Adult; Aldosterone; Blood Glucose; Blood Pressure; Clonidine; Diabetes Co | 1989 |
Urinary kallikrein excretion following chronic sinoaortic denervation in conscious dogs.
Topics: Aldosterone; Animals; Blood Pressure; Carotid Sinus; Catecholamines; Chromatography, High Pressure L | 1989 |
Hemodynamic and endocrine effects of acute and chronic administration of nifedipine.
Topics: Aldosterone; Arginine; Blood Pressure; Cardiac Output; Endocrine Glands; Female; Glucagon; Glycated | 1989 |
Normotension with decreased plasma renin activity and low serum ionic calcium levels: a prehypertensive state?
Topics: Adult; Aldosterone; Blood Pressure; Calcium; Female; Humans; Hypertension; Magnesium; Male; Middle A | 1989 |
Management of low-renin hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diuretics; Humans; | 1989 |
Nadolol antihypertensive effect and disposition in young and elderly adults with mild to moderate essential hypertension.
Topics: Adult; Aged; Aging; Aldosterone; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Hyper | 1989 |
Effect of benazepril monotherapy in subjects with hypertension associated with renal dysfunction.
Topics: Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; | 1989 |
Relationships between renin, aldosterone, blood pressure and renal function in hypertensive insulin-dependent diabetes mellitus.
Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Neuropathies; | 1989 |
[Effect of obzidan on hemodynamic indices and the renin and aldosterone levels of the blood plasma in patients with juvenile hypertension].
Topics: Adolescent; Adult; Aldosterone; Drug Evaluation; Drug Resistance; Hemodynamics; Humans; Hypertension | 1989 |
[The use of digoxin, lasix and finoptin in treating circulatory failure in hypertension].
Topics: Aged; Aldosterone; Digoxin; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Humans; Hy | 1989 |
[Primary hyperaldosteronism without arterial hypertension].
Topics: 18-Hydroxycorticosterone; Acidosis, Renal Tubular; Adenoma; Adrenal Gland Neoplasms; Adult; Aldoster | 1989 |
The effects of aging on urinary kallikreins and other vasoactive substances in essential hypertension.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Blood Pressure; Dinoprostone; Female; Humans; Hy | 1989 |
Urinary kallikrein excretion in neurogenic hypertension in the dogs: possible relationship between kallikrein excretion and catecholamines.
Topics: Aldosterone; Animals; Blood Pressure; Denervation; Dogs; Epinephrine; Female; Hypertension; Kallikre | 1989 |
Do weak mineralocorticoids affect the pathogenesis of hypertension in Cushing's disease?
Topics: Adult; Aldosterone; Cushing Syndrome; Female; Humans; Hypertension; Male; Middle Aged; Mineralocorti | 1989 |
Renin inhibition with A-64662: effect on blood pressure and hormonal response in man.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Dipeptides; Dose-Response Relationship, Drug; Drug Eval | 1989 |
Effect of single-administration captopril on plasma and urinary vasopressin in normotensive subjects and patients with essential hypertension and primary aldosteronism.
Topics: Adult; Aldosterone; Arginine Vasopressin; Captopril; Depression, Chemical; Female; Humans; Hyperaldo | 1989 |
Cardiovascular regulatory functions in elderly patients with hypertension.
Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Blood Pressure; Cardiovascular System; Female; Heart; H | 1989 |
Nisoldipine inhibition of sodium influx into aorta from aldosterone-salt-hypertensive rats.
Topics: Aldosterone; Animals; Aorta; Calcium; Calcium Channel Blockers; Hydrogen; Hypertension; Ion Exchange | 1989 |
The role of dopamine in nonmodulating hypertension.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Dopamine; Dose-Response | 1989 |
Steroids during development of genetic hypertension in rats of Lyon strain.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Blood Pressure; Body Weight; Creatinine; Hypertension | 1989 |
Internal desynchronization between circadian rhythms of plasma aldosterone and erythrocyte membrane-bound Na/K-ATPase.
Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Erythrocyte Membrane; Female; Humans; Hypertension | 1987 |
New findings in apparent mineralocorticoid excess.
Topics: Adrenocorticotropic Hormone; Aldosterone; Child; Child, Preschool; Cortisone; Female; Humans; Hydroc | 1987 |
Hypertension during extracorporeal membrane oxygenation: cause, effect, and management.
Topics: Aldosterone; Cardiac Output; Catecholamines; Humans; Hypertension; Infant, Newborn; Oxygenators, Mem | 1987 |
Pathogenesis of systemic hypertension and glomerular injury in the spontaneously hypertensive rat.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Catecholamines; Glomerular Filtration Rate; Hyperte | 1987 |
Arterial hypertension in acromegaly: altered dopaminergic control of aldosterone secretion.
Topics: Acromegaly; Adrenocorticotropic Hormone; Adult; Aldosterone; Cosyntropin; Female; Humans; Hypertensi | 1987 |
Effect of atrial natriuretic factor on aldosterone and its precursor steroid production in adrenal zona glomerulosa cells from spontaneously hypertensive rats.
Topics: 18-Hydroxycorticosterone; Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; | 1987 |
Systemic and renal hemodynamic changes after two-month treatment with enalapril in patients with essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Electrolytes; Enalapril; Female; Hemodynamics; Human | 1987 |
A ouabain-displacing factor in normal pregnancy, pregnancy-induced hypertension and pre-eclampsia.
Topics: Adult; Aldosterone; Cardenolides; Catecholamines; Digoxin; Female; Humans; Hypertension; Natriuretic | 1988 |
Inhibitory effect of enalapril on serum aldosterone in essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Enalapril; Female; Heart Rate; Humans; Hypertension; | 1987 |
Enalapril and atenolol in essential hypertension: attenuation of hypotensive effects in combination.
Topics: Aldosterone; Angiotensin II; Atenolol; Atrial Natriuretic Factor; Drug Interactions; Drug Therapy, C | 1988 |
Effects of thiazide on erythrocyte sodium and potassium concentrations and Na+K+ATPase in hypertensive patients.
Topics: Aldosterone; Benzothiadiazines; Diuretics; Erythrocytes; Humans; Hypertension; Male; Potassium; Reni | 1988 |
Angiotensin-responsive aldosterone-producing adenoma masquerades as idiopathic hyperaldosteronism (IHA: adrenal hyperplasia) or low-renin essential hypertension.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Dexamet | 1987 |
Captopril versus enalapril: a comparison of 24 h humoral and hypotensive effects.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Enalapril; Humans; Hypertension; Pept | 1987 |
Effects of corticotropin-releasing factor (CRF) on aldosterone and 18-hydroxycorticosterone in essential hypertension and primary aldosteronism.
Topics: 18-Hydroxycorticosterone; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Corticosterone; Cor | 1987 |
Effect of lisinopril monotherapy on renal hemodynamics.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Creatinine; Electrolytes; Ena | 1988 |
Antihypertensive activity of enalapril. Effect of ibuprofen and different salt intakes.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pr | 1987 |
[Plasma renin activity, levels of catecholamines and aldosterone in essential arterial hypertension treated with ACE inhibitors. Base values and values after stress].
Topics: Adult; Aldosterone; Catecholamines; Dopamine; Enalapril; Epinephrine; Humans; Hypertension; Male; No | 1987 |
Plasma cortisol and corticosteroid-binding globulin in essential hypertension.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Child; Child, Preschool; Female; | 1988 |
Mild hypertension in patients with suspected dilated cardiomyopathy: cause or consequence?
Topics: Adult; Aged; Aldosterone; Blood Pressure; Cardiomyopathy, Dilated; Electrolytes; Female; Heart Rate; | 1988 |
Hypertension in pseudohypoparathyroidism type I.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Catecholamines; Child; | 1988 |
[Acute hemodynamic and hormonal effects of enalapril in essential hypertension: relations between hormone levels and efficacy].
Topics: Aldosterone; Blood Pressure; Drug Evaluation; Enalapril; Heart Rate; Hemodynamics; Humans; Hypertens | 1988 |
[High plasma renin activity in chronic obstructive pulmonary disease].
Topics: Aged; Aldosterone; Female; Humans; Hypertension; Lung Diseases, Obstructive; Male; Middle Aged; Pept | 1988 |
[Clinical use of magnetic resonance tomography for assessing adrenal function in patients with arterial hypertension].
Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Diagnosis, Di | 1988 |
Modulation of left ventricular hypertrophy by dietary salt and inhibition of angiotensin converting enzyme.
Topics: Aldosterone; Animals; Body Weight; Cardiomegaly; Enalapril; Hypertension; Lisinopril; Peptidyl-Dipep | 1988 |
Severe hypertension with absent secondary sex characteristics due to partial deficiency of steroid 17 alpha-hydroxylase activity.
Topics: Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Aldost | 1987 |
Effect of elevated blood pressure, renin and aldosterone on renal sodium handling in two-kidney Goldblatt hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Female; Hypertension; Kidney; Rats; Rats, Inbred Strains; Rena | 1986 |
Augmentation of renal blood flow and sodium excretion in hypertensive patients during blood pressure reduction by intravenous administration of the dopamine1 agonist fenoldopam.
Topics: Adult; Aldosterone; Benzazepines; Blood Pressure; Dose-Response Relationship, Drug; Female; Fenoldop | 1987 |
The acute and chronic effects of betaxolol on blood pressure, renin-aldosterone, and renal function in essential hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Aldosterone; Betaxolol; Blood Pressure; Humans; Hypertension; Kid | 1987 |
Effect of glucocorticoid deficiency on arterial pressure in conscious spontaneously hypertensive rats.
Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Dexamethasone; Glucocorticoids; Hypertension; M | 1989 |
Chronic hypotensive effects of verapamil in angiotensin hypertension are steroid independent.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Chronic Disease; Dogs | 1989 |
Nitrendipine, a calcium-entry blocker. Renal and humoral effects in human arterial hypertension.
Topics: Adult; Aged; Aldosterone; Blood Volume; Body Fluids; Calcium Channel Blockers; Catecholamines; Elect | 1986 |
[Effects of diltiazem on developing blood pressure and accompanying cardiac and vascular hypertrophy in SHR].
Topics: Aldosterone; Animals; Aorta; Aortic Diseases; Benzazepines; Cardiomegaly; Diltiazem; Hindlimb; Hyper | 1985 |
Isomyosin transitions in ventricles of aldosterone-salt hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Cardiomegaly; Electrophoresis, Polyacrylamide Gel | 1986 |
Endogenous opioid peptides: do they mediate the acute antihypertensive action of clonidine in humans?
Topics: Adult; Aged; Aldosterone; beta-Endorphin; Blood Pressure; Clonidine; Endorphins; Humans; Hypertensio | 1986 |
Effect of chronic infusion of atrial natriuretic factor on plasma and urinary aldosterone, plasma renin activity, blood pressure and sodium excretion in 2-K, 1-C hypertensive rats.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Chronic Disease; Diuresis; Drug Eva | 1986 |
[Effect of atriopeptin on the plasma renin-angiotensin system in rats].
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Hypertension; Male; Rats; Rats, Inb | 1986 |
Plasma levels of atrial natriuretic peptide are raised in essential hypertension during low and high sodium intake.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Diet, Sodium-Restricted; Female; Humans; Hypert | 1987 |
[Human atrial natriuretic peptide: a secretory product of the heart and its significance for physiology and clinical practice].
Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Diuresis; Heart Failure; Humans; Hypertensio | 1987 |
[Possible correlations between the electrolyte picture and plasma levels of aldosterone in pregnancy complicated by hypertension].
Topics: Adenosine Triphosphatases; Aldosterone; Erythrocytes; Female; Humans; Hypertension; Potassium; Pregn | 1987 |
Hemodynamic and hormonal effects of atrial natriuretic factor in patients with essential hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Epinephrine; Female; Hemodynamics; Humans; Hypertensi | 1987 |
Aldosterone regulation during saline infusion: usefulness of aldosterone/cortisol ratio in the diagnosis of aldosterone-producing adenoma.
Topics: Adenoma; Aldosterone; Atrial Natriuretic Factor; Chromatography, High Pressure Liquid; Humans; Hydro | 1987 |
Plasma levels of human atrial natriuretic peptide in patients with hypertensive diseases.
Topics: Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Cross Reactions; Diet, Sodiu | 1987 |
Alpha-h-ANP injection in normals, low renin hypertension and primary aldosteronism.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Diuresis; Heart Rate; Humans; Hydroco | 1987 |
Changes in the plasma hANP level during long-term salt loading in patient with essential hypertension.
Topics: Aged; Aldosterone; Atrial Natriuretic Factor; Female; Humans; Hypertension; Male; Middle Aged; Norep | 1988 |
Renal, cardiovascular and hormonal effects of alpha-human atrial natriuretic peptide on essential hypertension.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Female; Heart; Humans; Hypertension; Kidney; Ma | 1987 |
Plasma levels of atrial natriuretic peptide in patients with borderline and essential hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Calcium; Female; Humans; Hypertension; Male; Renin | 1988 |
[Physiologic importance of atrial natriuretic peptide in volume expansion and hypertension: experimental studies].
Topics: Aldosterone; Animals; Antibodies, Monoclonal; Atrial Natriuretic Factor; Blood Pressure; Blood Volum | 1988 |
[Atrial natriuretic peptide (ANP) in essential hypertension: a humoral marker for salt sensitivity and hypertensive heart disease at a clinically asymptomatic stage?].
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Catecholamines; Female; Heart Disease | 1988 |
Efficacy and safety of cilazapril, a new angiotensin-converting enzyme inhibitor.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Benzothiadiazines; Blood Pressure; Cilazapril | 1988 |
[Role of atrial natriuretic peptide in the renal response to acute volume expansion in the normal and essential hypertensive patient].
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Volume; Female; Humans; Hypertension; Male; Mid | 1988 |
[Arterial hypertension with hyperkalemia, tubular acidosis and normal renal function: Gordon syndrome and/or pseudohypoaldosteronism type II?].
Topics: Acidosis, Renal Tubular; Aldosterone; Atrial Natriuretic Factor; Humans; Hyperkalemia; Hypertension; | 1988 |
Salt sensitivity in blacks. Salt intake and natriuretic substances.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Black People; Blood Pressure; Dinoprostone; Dopamine; | 1988 |
Radioimmunoassay of atrial natriuretic peptide in human plasma: application to studies of volume and blood pressure homeostasis.
Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Electrolytes; Extracellular Space; Heart Fai | 1988 |
Response of atrial natriuretic peptide to acute saline loading in essential hypertension.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Female; Glomerular Filtra | 1988 |
Does the renin-angiotensin-aldosterone system modify cardiac structure and function in essential hypertension?
Topics: Aldosterone; Cardiomegaly; Female; Humans; Hypertension; Male; Myocardium; Renin-Angiotensin System; | 1988 |
A new Australian kindred with the syndrome of hypertension and hyperkalaemia has dysregulation of atrial natriuretic factor.
Topics: Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Australia; Fludrocortisone; Humans; Hyperkal | 1988 |
Dopaminergic control of aldosterone secretion is not mediated by atrial natriuretic factor in patients with essential hypertension.
Topics: Aldosterone; Atrial Natriuretic Factor; Deoxyepinephrine; Dopamine; Humans; Hypertension; Metoclopra | 1988 |
Long-term antihypertensive treatment may induce normalization of left ventricular mass before complete regression of vascular structural changes: consequences for cardiac function at rest and during stress.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Drug Admi | 1988 |
Effects of chronically administered atrial natriuretic factor in aldosterone-infused hypertensive rats.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Hypertension; Infusions, Intravenou | 1988 |
[Role of ANP in the regulation of blood pressure].
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Humans; Hypertension; Sodium; Vasod | 1988 |
Plasma beta-endorphin levels in primary aldosteronism.
Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Age | 1985 |
[Concentration of adrenocorticotrophic hormone and aldosterone secretion in essential hypertension and hyperaldosteronism].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Humans; Hydrocortisone; Hyperaldosteronism; Hyperte | 1985 |
Adrenocortical function in deoxycorticosterone acetate (DOCA)-hypertensive Yucatan miniature swine.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; An | 1985 |
Cigarette smoking in hypertensive patients. Blood pressure and endocrine responses.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Endocrine Gla | 1985 |
Urinary 6-keto-PGF1 alpha after captopril and indomethacin: possible contribution of PGI2 to the antihypertensive mechanism of ACE inhibitors.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopri | 1985 |
Plasma Na+-K+ ATPase inhibitory activity in normal and hypertensive subjects: relationship to intracellular electrolytes and blood pressure.
Topics: Adult; Aldosterone; Animals; ATPase Inhibitory Protein; Blood Pressure; Blood Proteins; Electrolytes | 1985 |
The effect of long-term verapamil treatment on the secretion of cortisol and aldosterone in subjects with normal and high blood pressure.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hyp | 1985 |
[The acute effects of the new angiotensin I-converting enzyme inhibitor, enalapril maleate, on blood pressure, plasma renin, aldosterone and kinins in hypertensive patients].
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Brad | 1985 |
Relationships among endogenous digitalis-like factors in essential hypertension.
Topics: Aldosterone; Animals; Blood Proteins; Calcium; Cardenolides; Digoxin; Epinephrine; Humans; Hypertens | 1985 |
Effect of enalapril on renin, angiotensin converting enzyme activity, aldosterone and prostaglandins in patients with hypertension.
Topics: Adult; Aldosterone; Alprostadil; Creatinine; Dinoprostone; Enalapril; Female; Humans; Hypertension; | 1985 |
Enalapril in essential hypertension.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Catecholamines; Enalapril; Female | 1985 |
Natriuretic effect and changes in renal haemodynamics induced by enalapril in essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Enalapril; Female; Glomerul | 1985 |
Effect of sodium intake on the excretion of urinary natriuretic factor in essential hypertensives.
Topics: Aldosterone; Digoxin; Humans; Hypertension; Natriuretic Agents; Radioimmunoassay; Sodium; Sodium Chl | 1985 |
Effects of converting enzyme inhibition on blood pressure, plasma renin activity (PRA) and plasma aldosterone in hypertensive diabetics compared to patients with essential hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Diabetic Angiopath | 1985 |
Are non-modulating patients with essential hypertension a distinct subgroup? Implications for therapy.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Female; Furosemide; Humans; Hypertension; Kidney | 1985 |
Blood pressure response to enalaprilic acid in essential hypertension: dose-response and effect of pre-treatment with furosemide.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Dose-Response Re | 1985 |
24-H patterns of erythrocyte membrane-bound Na/K ATPase, plasma renin and aldosterone in normotensives and essential hypertensives.
Topics: Adolescent; Adult; Aldosterone; Erythrocyte Membrane; Female; Humans; Hypertension; Male; Renin; Sod | 1985 |
Acute effects of the new oral angiotensin converting enzyme inhibitor 1-(D-3-acetylthio-2-methylpropanoyl)-L-prolyl-L-phenylalanine (Alacepril) in essential hypertension.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; | 1985 |
Changes in blood pressure and body fluid volumes during diuretic therapy in patients with essential hypertension who receive enalapril.
Topics: Aged; Aldosterone; Blood Pressure; Body Fluids; Body Weight; Chlorthalidone; Creatinine; Drug Evalua | 1986 |
Non-modulating essential hypertension: a subset particularly responsive to converting enzyme inhibitors.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertens | 1985 |
[Round-table conference "Biochemical diagnosis of arterial hypertension"].
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Catechol | 1985 |
Diagnosis and pathophysiology of Cushing's syndrome.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Cushing Syndrome; Femal | 1986 |
[Clinical significance of serum angiotensin I-converting enzyme in essential hypertension].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Bradykinin; Circadian Rhythm; Creatinine; | 1985 |
Dopaminergic control of aldosterone secretion in hypertensive patients chronically treated with an angiotensin converting enzyme inhibitor.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme | 1986 |
Renal sodium excretion and atrial natriuretic factor.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Extracellular Space; Glomerular Filtration Rate; Hu | 1986 |
Effect of alacepril on renin-angiotensin-aldosterone system and kallikrein-kinin-prostaglandin system in experimental animals.
Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Angiotensin I; Animals; Antihypertensive Agents; Blood Pr | 1986 |
[Various humoral factors regulating blood pressure in patients with hypertension during treatment by an impulse magnetic field].
Topics: Adult; Aldosterone; Blood Pressure; Cyclic AMP; Cyclic GMP; Dinoprost; Female; Homeostasis; Humans; | 1986 |
Cortisol resistance in man.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Alkalosis; Cell Transformation, Viral; Child; Circa | 1986 |
[Arterial hypertension in alcohol withdrawal syndrome].
Topics: Adult; Aged; Aldosterone; Cyclic AMP; Ethanol; Female; Humans; Hypertension; Male; Middle Aged; Reni | 1986 |
Studies on the antihypertensive effect of single doses of the angiotensin converting enzyme inhibitor ramipril (HOE 498) in man.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood P | 1986 |
[Results of a 5-year study with captopril in patients with severe therapy-resistant hypertension].
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Drug | 1986 |
[Mechanisms of hypertension in patients with terminal kidney failure on programmed hemodialysis].
Topics: Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Kidney Failure, Chronic; Peptidyl-Dipeptid | 1986 |
Zona glomerulosa cell responses to atrial natriuretic factor in genetically hypertensive rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood | 1986 |
Effect of nifedipine in hypertension not controlled by converting enzyme inhibitor and diuretic.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Drug Therapy, Combination; Enalapril; Female; Furosem | 1986 |
Enalaprilat: an intravenous substitute for oral enalapril therapy. Humoral and pharmacokinetic effects.
Topics: Administration, Oral; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihyp | 1986 |
Spironolactone-reversible rickets associated with 11 beta-hydroxysteroid dehydrogenase deficiency syndrome.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenocorticotropic Hormone; Aldosterone; Alkalosis; Bone and | 1986 |
[Clinical pharmacology of enalapril in hypertension with chronic renal failure].
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Enalapril; Heart Rate; Humans | 1986 |
Humoral and blood pressure effects of the angiotensin converting enzyme inhibitor ramipril in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressur | 1986 |
Effects of aldosterone and adrenocorticotropic hormone on urinary kallikrein excretion.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hypertension; Infusions, Intravenou | 1986 |
[Mechanisms of the hypotensive action of captopril in essential hypertension].
Topics: Adult; Aldosterone; Captopril; Epinephrine; Hemodynamics; Humans; Hypertension; Kallikreins; Middle | 1986 |
[Influence of endogenous renin-angiotensin system on plasma aldosterone responsiveness to metoclopramide].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Diuretics; Dopamine; Female; Humans; Hyperaldostero | 1987 |
Lisinopril in hypertensive patients with and without renal failure.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Creatinine; Enal | 1987 |
Characterization of the alpha-1 adrenergic receptors in the thoracic aorta of control and aldosterone hypertensive rats: correlation of radioligand binding with potassium efflux and contraction.
Topics: Aldosterone; Angiotensin II; Animals; Aorta, Thoracic; Dibenzylchlorethamine; Hypertension; Muscle C | 1987 |
[Effects of alpha-human atrial natriuretic peptide on plasma steroids and renal function in the human].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Catechol | 1987 |
Effects of enalapril maleate on blood pressure, renin-angiotensin-aldosterone system, and peripheral sympathetic activity in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Enalapril; Exercise Test; Female; Humans; Hypert | 1987 |
Single oral administration of captopril may not bring an improvement in screening of primary aldosteronism.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diet; Humans; Hyperaldosteronism; | 1987 |
Effect of beta-adrenergic receptor blockade on atrial natriuretic peptide in essential hypertension.
Topics: Acebutolol; Adult; Aged; Aldosterone; Atenolol; Atrial Natriuretic Factor; Cyclic GMP; Female; Human | 1987 |
Sodium excretion in normal and hypertensive pregnancy: a prospective study.
Topics: Aldosterone; Cross-Sectional Studies; Diet; Diet, Sodium-Restricted; Female; Humans; Hypertension; I | 1988 |
[Influence of sodium intake on antihypertensive effect of calcium antagonist].
Topics: Administration, Oral; Aldosterone; Blood Pressure; Catecholamines; Female; Heart Rate; Humans; Hyper | 1988 |
Natriuretic and renal hemodynamic effects of nicardipine in essential hypertension.
Topics: Administration, Oral; Aldosterone; Blood Pressure; Heart Rate; Hemodynamics; Humans; Hypertension; I | 1988 |
Normal vitamin D and mineral metabolism in essential hypertension.
Topics: Adult; Aldosterone; Calcifediol; Calcitriol; Calcium; Creatinine; Electrolytes; Female; Humans; Hype | 1988 |
[Effect of captopril on renin-aldosterone system in essential hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Captopril; Chromatography, High Pressure Liquid; Female; Humans; | 1988 |
[The role of hormonal factors in the pathogenesis of juvenile arterial hypertension].
Topics: Adolescent; Adult; Aldosterone; Estradiol; Exercise Test; Humans; Hypertension; Renin; Testosterone | 1988 |
Biochemical changes associated with thermal biofeedback treatment of hypertension.
Topics: Adult; Aged; Aldosterone; Biofeedback, Psychology; Blood Pressure; Female; Humans; Hypertension; Mal | 1988 |
Influence of sublingual captopril on plasma catecholamine levels during hypertensive emergencies and cold immersion.
Topics: Administration, Sublingual; Adult; Aged; Aldosterone; Blood Pressure; Captopril; Catecholamines; Col | 1988 |
[Effects of high sodium diet on dopaminergic mechanism in normal and hypertensive subjects].
Topics: Adult; Aldosterone; Blood Pressure; Dopamine; Epinephrine; Heart Rate; Humans; Hypertension; Metoclo | 1988 |
[Effect of immersion (WI) in mineral water on plasma renin activity (PRA) and aldosterone (ALD) and vasopressin (VP) levels in the blood of patients with arterial hypertension].
Topics: Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Immersion; Mineral Waters; Renin; Vasopres | 1988 |
Sodium-renin-aldosterone relations in normal and hypertensive pregnancy.
Topics: Adult; Aldosterone; Blood Volume; Diet, Sodium-Restricted; Female; Humans; Hypertension; Pregnancy; | 1988 |
[A 54-year-old patient with muscle weakness, hypokalemia and arterial hypertension].
Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Female; Humans; Hypertension; Hypokalemia; Middle Ag | 1988 |
Intracellular free Ca2+ in platelets of essential hypertensive patients. Lack of correlation with clinical and laboratory data.
Topics: Adolescent; Adult; Aldosterone; Blood Platelets; Blood Pressure; Calcium; Cholesterol; Female; Human | 1988 |
The effect of ageing on the plasma renin-angiotensin-aldosterone system in elderly hypertensive patients.
Topics: Aged; Aged, 80 and over; Aging; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin; | 1988 |
Cardiovascular and neurohormonal changes following central sympathetic blockade with clonidine in human unilateral renal artery stenosis.
Topics: Adult; Aged; Aldosterone; Captopril; Clonidine; Hemodynamics; Humans; Hypertension; Middle Aged; Nor | 1988 |
Norepinephrine and calcium responses to altered sodium intake in modulating and non-modulating high-renin hypertension.
Topics: Aldosterone; Blood Pressure; Calcium; Humans; Hypertension; Norepinephrine; Renin; Sodium | 1988 |
[Changes in the indicators of the renin-angiotensin-aldosterone system, kallikrein-kinin system and arterial blood pressure in elderly patients with essential hypertension treated with captopril].
Topics: Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Captopril; Female; Humans; Hypertension; Kall | 1988 |
[Studies of the effect of bromocriptine on the serum prolactin, aldosterone and cortisol levels and plasma renin activity in patients with essential hypertension].
Topics: Adult; Aldosterone; Bromocriptine; Enzyme Inhibitors; Humans; Hydrocortisone; Hypertension; Middle A | 1988 |
Mechanisms of cyclosporine A hypertension.
Topics: Aldosterone; Animals; Arteries; Blood Pressure; Captopril; Cyclosporins; Electric Stimulation; Hyper | 1987 |
Infected hand injury in a hypertensive patient.
Topics: Adrenal Glands; Adult; Aldosterone; Antihypertensive Agents; Hand Injuries; Humans; Hyperplasia; Hyp | 1987 |
[Hemodynamic indices and the renin and aldosterone levels of the blood plasma in patients with different forms of arterial hypertension undergoing combined kristepin and propranolol treatment].
Topics: Adolescent; Adult; Aldosterone; Clopamide; Dihydroergotoxine; Drug Combinations; Drug Therapy, Combi | 1988 |
Short- and long-term efficacy of nifedipine in hypertensive patients with impaired renal function, with special reference to influencing factors.
Topics: Adult; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Creatinine; Female; Humans; Hypertension; K | 1987 |
[Acute response to calcium inhibitors in secondary arterial hypertension: does renin play a role?].
Topics: Adult; Aldosterone; Blood Pressure; Heart Rate; Humans; Hyperaldosteronism; Hypertension; Hypertensi | 1988 |
[Segmental renal hypoplasia of an adult originating from pseudo-tumor hyperreninism].
Topics: Adult; Aldosterone; Captopril; Humans; Hypertension; Kidney; Male; Microscopy, Electron; Nephrectomy | 1988 |
Prevalence and clinical peculiarities of essential hypertension in a population living at high altitude.
Topics: Adult; Age Factors; Aldosterone; Alkalosis, Respiratory; Altitude; Altitude Sickness; Cardiomegaly; | 1985 |
Urinary kallikrein in mild to moderate essential hypertension.
Topics: Aldosterone; Female; Furosemide; Humans; Hypertension; Kallikreins; Male; Middle Aged; Natriuresis; | 1985 |
Participation of endogenous catecholamines in the regulation of left ventricular mass in progeny of hypertensive parents.
Topics: Adolescent; Adult; Aldosterone; Atenolol; Blood Pressure; Blood Volume; Body Weight; Cardiomegaly; C | 1985 |
Influence of an enriched dietary sodium chloride regime during gestation and suckling and post-natally on the ontogeny of hypertension in the rat.
Topics: 18-Hydroxydesoxycorticosterone; Aldosterone; Angiotensin I; Animals; Animals, Suckling; Blood Pressu | 1988 |
[Is the renin-angiotensin system implicated in the hypertensive effect of a water-soluble tissue extract?].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cattle; Female; Hypertension; Male; Rats; Rats | 1988 |
Aldosterone and magnesium in essential arterial hypertension.
Topics: Adult; Aldosterone; Calcium; Female; Humans; Hypertension; Magnesium; Male; Middle Aged; Potassium | 1988 |
A case of glucocorticoid-suppressible hyperaldosteronism with aldosterone producing adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Dexamethasone; Female; Glucoco | 1988 |
[Aldosterone metabolites in spontaneously hypertensive rats].
Topics: Aldosterone; Animals; Chromatography, High Pressure Liquid; Cytoplasm; Hypertension; Injections, Int | 1988 |
Mineralocorticoids are not involved in the antihypertensive effect of neonatal thymectomy in the genetically hypertensive LH rat.
Topics: Aldosterone; Animals; Animals, Newborn; Blood Pressure; Desoxycorticosterone; Disease Models, Animal | 1988 |
[A syndrome of arterial hypertension caused by a combination of 2 adrenal gland tumors].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hypertension; Neoplasms, Multi | 1988 |
Dopamine and aldosterone in adrenal glomerulosa cells in spontaneously hypertensive rats.
Topics: Adrenal Glands; Adrenal Medulla; Aldosterone; Animals; Catecholamines; Dopamine; Hypertension; Rats; | 1988 |
Effects of intracerebroventricular infusion of aldosterone on blood pressure and sodium and potassium concentrations in cerebral spinal fluid in rats.
Topics: Aldosterone; Animals; Blood Pressure; Brain; Hypertension; Infusion Pumps; Male; Potassium; Rats; Ra | 1988 |
Urinary excretion of aldosterone metabolite Kelly-M1 in patients with adrenal dysfunction.
Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Aldosterone; Cysti | 1988 |
Zona glomerulosa function after life-long suppression in two siblings with the hypertensive virilizing form of congenital adrenal hyperplasia.
Topics: 18-Hydroxycorticosterone; Adolescent; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Aldosterone; | 1988 |
Therapeutic results of primary aldosteronism with special reference to renal or renovascular lesions.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Diet, Sodium-Restricted; Female; Furosemide; H | 1988 |
Steroid-induced hypertension in patients with nephrotic syndrome.
Topics: Adolescent; Adult; Aldosterone; Blood Volume; Female; Glomerulonephritis; Humans; Hypertension; Male | 1988 |
Acute hypertensive and natriuretic responses following preoptic hypothalamic lesions.
Topics: Aldosterone; Animals; Blood Pressure; Blood Volume; Corticosterone; Heart Rate; Hypertension; Male; | 1988 |
Sodium sensitivity in normotensive and borderline hypertensive humans.
Topics: Aldosterone; Black People; Blood Pressure; Body Weight; Cardiac Output; Conjunctiva; Echocardiograph | 1988 |
[Plasma levels of catecholamine, renin activity and aldosterone during operations in patients with hypertension].
Topics: Adult; Aged; Aldosterone; Catecholamines; Female; Humans; Hypertension; Male; Middle Aged; Renin; Su | 1988 |
Effect of penbutolol on circadian blood pressure, and renin, aldosterone and cortisol levels in patients with essential hypertension.
Topics: Administration, Oral; Adult; Aldosterone; Blood Pressure; Circadian Rhythm; Female; Humans; Hydrocor | 1988 |
Long-term systemic hypertension in children after successful repair of coarctation of the aorta.
Topics: Aldosterone; Aortic Coarctation; Blood Pressure; Child; Female; Heart Rate; Humans; Hypertension; Ma | 1988 |
Sodium sensitivity in human subjects. Hemodynamic and hormonal correlates.
Topics: Adult; Aldosterone; Female; Hemodynamics; Humans; Hypertension; Male; Renin; Sodium, Dietary | 1988 |
The pattern of plasma renin activity and aldosterone system in patients with sustained hydronephrosis.
Topics: Adolescent; Adult; Aldosterone; Child; Female; Humans; Hydronephrosis; Hypertension; Kidney; Male; M | 1987 |
Effect of high calcium intake on pressor responsivity in hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Calcium, Dietary; Dose-Response Relationship, | 1987 |
[Radioimmunologic determination of aldosterone and renin in the blood in the diagnosis of different forms of arterial hypertension].
Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Rena | 1987 |
Effect of one year of thiazide therapy on plasma volume, renin, aldosterone, lipids and urinary metanephrines in systolic hypertension of elderly patients.
Topics: Aged; Aldosterone; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Lipids; Metanephrin | 1987 |
The gerontological decline of the renin-aldosterone system: a chronobiological approach extended to essential hypertension.
Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Circadian Rhythm; Female; Humans; Hypertension; Male; M | 1987 |
Effects of sodium intake on the captopril test for primary aldosteronism.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Diet; Female; Humans; Hyperaldosteronism; Hypertensio | 1987 |
[The renin-angiotensin-aldosterone system in obesity associated with essential arterial hypertension].
Topics: Aldosterone; Circadian Rhythm; Humans; Hypertension; Obesity; Renin; Renin-Angiotensin System | 1987 |
Renin suppression by saline is blunted in nonmodulating essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; | 1987 |
"Salt-sensitive" essential hypertension in men. Is the sodium ion alone important?
Topics: Aged; Aldosterone; Blood Pressure; Body Weight; Citrates; Citric Acid; Humans; Hypertension; Male; M | 1987 |
Essential arterial hypertension: plasma and urinary aldosterone alterations.
Topics: Adult; Age Factors; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin; Sodium | 1987 |
Efficacy and safety of lasilactone, a new combination diuretic, in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Drug Combinations; Female; Furosemide; Humans; Hypertension; Mal | 1987 |
Renin and aldosterone in hypertensive blacks.
Topics: Adult; Aged; Aldosterone; Black People; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1987 |
[Detection of primary aldosteronism using the captopril test].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Captopril; Female; Humans; Hyp | 1987 |
[Renin-angiotensin-aldosterone system in hypertension patients who have had a cerebral stroke].
Topics: Aged; Aldosterone; Cerebrovascular Disorders; Chronic Disease; Humans; Hypertension; Middle Aged; Re | 1987 |
[Structural and functional status of the adrenal cortex in patients with arterial hypertension (comparison of computerized-tomographic and clinico-biochemical data)].
Topics: 17-Ketosteroids; Adrenal Cortex; Aldosterone; Humans; Hydrocortisone; Hypertension; Renin; Tomograph | 1987 |
Dopamine blockade abolishes the exaggerated natriuresis of essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Creatinine; Humans; Hypertension; Immersion; Male; Metoclopramid | 1987 |
Role of renal kallikrein in modulating the antihypertensive effect of a single oral dose of captopril in normal- and low-renin essential hypertensives.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Diuresis; Female; Humans; Hypertension; Kallikreins; | 1987 |
Effects of calcium loading in DOCA-salt hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Calcium; Desoxycorticosterone; Drinking; Epinephr | 1987 |
Hemodynamic and neurohumoral factors in the response of hypertensives to hydrochlorothiazide therapy.
Topics: Aldosterone; Benzothiadiazines; Blood Pressure; Diuretics; Epinephrine; Female; Hemodynamics; Humans | 1987 |
Calcium antagonists and responsiveness of the adrenal glands to aldosterone-releasing stimuli in hypertensive patients.
Topics: Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Calcium Channel Blockers; Drug Evaluation; | 1987 |
Effects of felodipine and metoprolol on blood pressure, plasma renin, angiotensin II, aldosterone and catecholamines in hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Electro | 1987 |
Blunted aldosterone responsiveness to angiotensin II in normotensive subjects with familial predisposition to essential hypertension.
Topics: Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Humans; Hypertension; Male; Sodium, Dietary | 1988 |
Hypertensive mechanisms associated with centrally administered aldosterone in dogs.
Topics: Aldosterone; Hemodynamics; Hypertension; Injections, Intraventricular; Injections, Subcutaneous; Mal | 1988 |
[Studies on abnormalities of adrenal steroidogenesis in essential hypertension, primary aldosteronism and renovascular hypertension: responses of plasma steroids to angiotensin III].
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adult; Aldosterone; Angiotensin II; Angiotensin III; Circad | 1988 |
Dose-response studies of intracerebroventricular infusion of aldosterone in sensitized and non-sensitized rats.
Topics: Aldosterone; Animals; Cerebral Ventricles; Dose-Response Relationship, Drug; Hypertension; Infusions | 1988 |
Lack of increase in sodium concentration of cerebrospinal fluid in DOCA-salt hypertensive rats.
Topics: 18-Hydroxycorticosterone; Adrenalectomy; Aldosterone; Animals; Arginine Vasopressin; Blood Pressure; | 1988 |
Primary aldosteronism at Henry Ford Hospital in the 1980s.
Topics: Adrenalectomy; Adult; Aldosterone; Combined Modality Therapy; Female; Humans; Hyperaldosteronism; Hy | 1987 |
[Primary hyperaldosteronism: diagnosis, treatment and histopathological findings in 15 cases].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Female; Humans; Hyperaldostero | 1987 |
Apparent mineralocorticoid excess causing hypertension and hypokalemia in children.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Child; Child, Preschool; Female; Humans; Hydroco | 1986 |
Humoral factors involved in the regulation of sodium-fluid balance in man. III. Renal prostaglandins and renin-angiotensin-aldosterone system in hypertensive disorders.
Topics: Aldosterone; Dinoprost; Dinoprostone; Epinephrine; Humans; Hypertension; Hypertension, Renal; Kidney | 1986 |
Cellular sodium turnover in obese hypertensive men.
Topics: Adult; Aldosterone; Erythrocytes; Humans; Hypertension; Male; Middle Aged; Obesity; Potassium; Sodiu | 1986 |
Circadian rhythms of urinary sodium, potassium and some agents influencing their excretion in young borderline hypertensives.
Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Corticosterone; Desoxycorticosterone; Dinoprost; D | 1986 |
Immediate and short-term hemodynamic effects of diltiazem in patients with hypertension.
Topics: Adult; Aged; Aldosterone; Benzazepines; Blood Pressure; Diltiazem; Dopamine; Epinephrine; Female; He | 1986 |
Multiple factors contribute to the pathogenesis of hypertension in Cushing's syndrome.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Captopr | 1986 |
New insights into the medical management of primary aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Angiotensin II; Calcium Channel Blockers; Fem | 1986 |
Hypertension and kidney transplantation.
Topics: Aldosterone; Animals; Cyclosporins; Electrolytes; Glucocorticoids; Graft Survival; Hormones; Humans; | 1986 |
Short-term augmented calcium intake has no effect on sodium homeostasis.
Topics: Administration, Oral; Adult; Aldosterone; Analysis of Variance; Blood Pressure; Calcium; Creatinine; | 1986 |
Detection of primary aldosteronism by the 6-hour integrated aldosterone/renin ratio.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Blood Pressure; Female; Humans; Hyperald | 1986 |
Interplay of various factors in glucose-induced hyperkalemia during captopril treatment.
Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Captopril; Glomerular Filtration Rate; Glucose; G | 1986 |
Hypertension and hypokalaemia due to a renin-secreting kidney tumour. Primary reninism.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Hypokalemia; Kidney Neoplasms; Renin | 1986 |
[Radioimmunologic analysis of the status of the renin-angiotensin-aldosterone system in arterial hypertension].
Topics: Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension; Radioimmunoassay; Renin | 1986 |
Renal kallikrein in diabetic patients with hypertension accompanied by nephropathy.
Topics: Adult; Aged; Aldosterone; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; | 1986 |
Spectrum of deranged sodium homeostasis in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Creatinine; Homeostasis; Humans; Hypertension; Immersion; Male; | 1986 |
[Progressive hyperkalemia during chronic captopril therapy (pharmacological hypoaldosteronism)].
Topics: Aged; Aldosterone; Captopril; Dose-Response Relationship, Drug; Humans; Hyperkalemia; Hypertension; | 1986 |
Body sodium/blood volume state in normotensive members of normotensive and hypertensive families.
Topics: Aldosterone; Blood Pressure; Blood Volume; Humans; Hypertension; Male; Renin; Sodium; Water-Electrol | 1986 |
Blood pressure control in normotensive members of hypertensive families.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Creatinine; Dose-Response Relationship, Drug; Ep | 1986 |
Antihypertensive effect of a new calcium channel blocker, FK 235, in essential hypertension.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hyperte | 1986 |
Effect of exercise on plasma concentrations of arginine vasopressin, angiotensin II and aldosterone in hypertensive and normotensive renal transplant recipients.
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Blood Pressure; Exercise Test; Female; Hea | 1986 |
Diurnal patterns of blood pressure, heart rate and vasoactive hormones in normal man.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Catecholamines; Circadian Rhythm; Female; Heart | 1986 |
The renin-angiotensin system in hypothyroidism of short duration.
Topics: Adult; Aldosterone; Electrophysiology; Female; Humans; Hypertension; Hypothyroidism; Intestinal Muco | 1986 |
[Dynamic model of the circadian rhythm of renin activity and aldosterone concentration in the blood plasma of hypertension patients].
Topics: Adult; Aldosterone; Circadian Rhythm; Humans; Hypertension; Male; Middle Aged; Renin | 1986 |
Excessive sodium retention as a characteristic of salt-sensitive hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Blood Volume; Body Weight; Creatinine; Female; Humans; Hypertens | 1986 |
Suppression of plasma renin and aldosterone in stress-salt hypertension in dogs.
Topics: Aldosterone; Animals; Avoidance Learning; Cardiovascular System; Dogs; Female; Heart Rate; Hypertens | 1986 |
The syndrome of hypertension and hyperkalaemia with normal GFR. A unique pathophysiological mechanism for hypertension?
Topics: Adult; Aldosterone; Diet; Female; Glomerular Filtration Rate; Humans; Hyperkalemia; Hypertension; Ki | 1986 |
Lack of effect of nifedipine on counterregulatory mechanisms in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Catecholamines; Female; Glomerular Filtration Rate; Humans | 1986 |
Is single oral administration of captopril beneficial in screening for primary aldosteronism?
Topics: Adult; Aldosterone; Angiotensin II; Captopril; Diagnosis, Differential; Diet, Sodium-Restricted; Hum | 1986 |
Central renin-angiotensin system and the pathogenesis of DOCA-salt hypertension in rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain; Captopril; Desoxycortico | 1986 |
The effect of 8 weeks treatment with the calcium antagonist felodipine on blood pressure, heart rate, working capacity, plasma renin activity, plasma angiotensin II, urinary catecholamines and aldosterone in patients with essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Catecholamines; Felodipine; Heart Rate; | 1986 |
Renal prostaglandin E in sustained severe hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Prostag | 1986 |
Mineralocorticoid-induced kaliuresis in type-II pseudohypoaldosteronism.
Topics: Acidosis; Adult; Aldosterone; Benzothiadiazines; Desoxycorticosterone; Diuretics; Humans; Hyperkalem | 1986 |
Renin-angiotensin-aldosterone system: a long-term follow-up study in 17 alpha-hydroxylase deficiency syndrome (17OHDS).
Topics: Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Female; Glucocortic | 1986 |
A case of adrenal tumor producing renin, aldosterone, and sex steroid hormones.
Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Carcinoma; Female; Gon | 1986 |
Diagnostic value of captopril test in primary aldosteronism.
Topics: Adult; Aldosterone; Captopril; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; | 1986 |
Effects of intravenous administration of a calcium antagonist on prostaglandins and thromboxane in plasma and urine in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Blood Pressure; Calcium Channel Blockers; Dinopros | 1986 |
Effects of volume expansion and contraction on potassium homeostasis in normal and hypertensive humans.
Topics: Adult; Aldosterone; Black People; Blood Volume; Creatinine; Diet, Sodium-Restricted; Female; Furosem | 1986 |
Effect of exogenous angiotensin II infusion after one year of captopril therapy in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Captopril; Female; Humans; Hypertension; Male; Renin; Time Facto | 1986 |
Systemic systolic hypertension in the elderly: correlation of hemodynamics, plasma volume, renin, aldosterone, urinary metanephrines and response to thiazide therapy.
Topics: Aged; Aged, 80 and over; Aldosterone; Epinephrine; Hemodynamics; Humans; Hydrochlorothiazide; Hypert | 1986 |
[Decreased activity of the renal vasodilation and natriuretic system in normotensive men with a familial history of essential hypertension and decreased Na+, K+-cotransport in erythrocytes].
Topics: Adult; Aldosterone; Carrier Proteins; Erythrocytes; Humans; Hydrocortisone; Hypertension; Kallikrein | 1986 |
Long term evolution of glucocorticoid-suppressible hyperaldosteronism.
Topics: Adolescent; Aldosterone; Dexamethasone; Humans; Hyperaldosteronism; Hypertension; Male; Posture; Ren | 1987 |
Plasma aldosterone-plasma renin activity ratio. A simple test to identify patients with primary aldosteronism.
Topics: Adult; Aged; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension; | 1986 |
Suppression of adrenal renin in Dahl salt-sensitive rats.
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex; Aldosterone; Animals; Diet, Sodium-Restricted; Femal | 1986 |
Circadian rhythm of plasma renin activity in older normal and essential hypertensive men: relation with inactive renin, aldosterone, cortisol and REM sleep.
Topics: Aging; Aldosterone; Angiotensinogen; Circadian Rhythm; Enzyme Precursors; Humans; Hydrocortisone; Hy | 1986 |
The renin-angiotensin system is not responsible for hypertension following coronary artery bypass grafting.
Topics: Adult; Aldosterone; Angiotensin II; Cardiopulmonary Bypass; Hemodynamics; Humans; Hypertension; Midd | 1987 |
The effects of acebutolol alone and in combination with furosemide or hydralazine in experimentally induced hypertensive G-minipigs.
Topics: Acebutolol; Aldosterone; Animals; Drug Therapy, Combination; Female; Furosemide; Heart Rate; Hydrala | 1986 |
An abnormal response of the adrenal cortex to insulin: glucose in essential hypertension.
Topics: Adrenal Cortex; Aldosterone; Bendroflumethiazide; Blood Pressure; Glucose; Humans; Hydrocortisone; H | 1986 |
Thiazide induced hypotension: the role of plasma volume reduction and the urinary kallikrein system.
Topics: Aldosterone; Blood Pressure; Humans; Hydrochlorothiazide; Hypertension; Hypotension; Kallikreins; Ma | 1986 |
Acute effect of furosemide on renal kallikrein and prostaglandin systems in mild to moderate essential hypertension.
Topics: Aldosterone; Female; Furosemide; Hemodynamics; Humans; Hypertension; Kallikreins; Male; Middle Aged; | 1987 |
[Level of prostaglandins, cyclic nucleotides, renin and aldosterone in the plasma of patients with essential hypertension].
Topics: Adult; Aldosterone; Humans; Hypertension; Middle Aged; Nucleotides, Cyclic; Prostaglandins; Renin | 1987 |
System dynamics modeling of renin aldosterone and electrolyte changes induced by furosemide in hypertensive patients.
Topics: Adult; Aldosterone; Computers; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Models, | 1987 |
Natriuresis and the renin axis in sodium-sensitive man.
Topics: Aldosterone; Blood Pressure; Drug Resistance; Extracellular Space; Furosemide; Humans; Hypertension; | 1986 |
Influence of genetic variance on sodium sensitivity of blood pressure.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Diseases in Twins; Female; | 1987 |
Elevated urinary 19-Nor-deoxycorticosterone glucuronide in Cushing's syndrome.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Carcinoma; Cushing Syndrome; Desoxycort | 1987 |
Acute haemodynamic and humoral responses to felodipine and metoprolol in mild hypertension.
Topics: Adult; Aldosterone; Antihypertensive Agents; Calcium Channel Blockers; Catecholamines; Drug Therapy, | 1987 |
[Effect of treatment with pindolol on the renin-angiotensin-aldosterone system, kidney function and electrolyte balance in patients with primary arterial hypertension].
Topics: Adolescent; Adult; Aldosterone; Humans; Hypertension; Kidney; Male; Middle Aged; Pindolol; Renin-Ang | 1986 |
[Determination of pregnancy plasma angiotensin II and aldosterone level in hypertensive states].
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardi | 1987 |
[Studies on the significance of 17 alpha,20 alpha-dihydroxy-4-pregnen-3-one (17 alpha,20 alpha-P) in pregnancy induced hypertension (PIH) and its site of production].
Topics: Aldosterone; Female; Fetal Blood; Humans; Hydroxyprogesterones; Hypertension; In Vitro Techniques; I | 1987 |
Calcium, the renin-aldosterone system, and the hypotensive response to nifedipine.
Topics: Aldosterone; Blood Pressure; Calcium; Humans; Hypertension; Nifedipine; Renin-Angiotensin System | 1987 |
Bootstrapped potential circadian harbingers if not determinants of cardiovascular risk.
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Circadian Rhythm; Female; Humans; Hydrocortisone; Hy | 1987 |
Central role for sodium in the pathogenesis of blood pressure changes independent of angiotensin, aldosterone and catecholamines in type 1 (insulin-dependent) diabetes mellitus.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Diabetes Mellitus, Typ | 1987 |
[Role of renal dopamine receptor in the pathogenesis of hypertension after sodium loading].
Topics: Aldosterone; Animals; Dopamine; Hypertension; Kidney; Male; Rats; Rats, Inbred Strains; Receptors, D | 1986 |
Abnormal vasopressin and aldosterone response to furosemide in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Electrolytes; Female; Furosemide; Humans; | 1986 |
Role of sulfate conjugation of catecholamines in blood pressure regulation.
Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Aldosterone; Animals; Blood Pressure; Catecholamines; Dogs; | 1986 |
[Effect of urapidil on adrenal cortex activity and prolactin secretion in patients with idiopathic hypertension].
Topics: Adrenal Cortex; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; | 1986 |
[Clinical significance and characteristics of the radioimmunologic determination of aldosterone levels in serum (plasma)].
Topics: Adolescent; Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension | 1986 |
HPLC isolation and GC-MS characterization of a compound strongly cross reacting with tetrahydroaldosterone antiserum.
Topics: Aldosterone; Chromatography, High Pressure Liquid; Chromatography, Paper; Cross Reactions; Gas Chrom | 1986 |
[Fundamental evaluation of aldosterone by aldosterone radioimmunoassay kit II].
Topics: Aldosterone; Evaluation Studies as Topic; Humans; Hyperaldosteronism; Hypertension; Radioimmunoassay | 1986 |
Abnormal renal sodium handling in essential hypertension. Relation to failure of renal and adrenal modulation of responses to angiotensin II.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Humans; | 1986 |
A simple method for definition of incomplete suppression of aldosterone and its association with hypertension and hypokalaemia in man.
Topics: Aged; Aldosterone; Diet, Sodium-Restricted; Female; Humans; Hyperaldosteronism; Hypertension; Hypoka | 1986 |
[Diagnosis of primary aldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Diagnosis, Differential | 1986 |
[How do gestational hormones modify sodium balance? Contribution to the genesis of "pill hypertension"].
Topics: Aldosterone; Contraceptives, Oral, Hormonal; Female; Humans; Hypertension; Progesterone; Water-Elect | 1986 |
Effect of sodium balance and calcium channel-blocking drugs on plasma aldosterone responses to infusion of angiotensin II in normal subjects and patients with essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Calcium; Calcium Channel Blockers; Diet, Sodium-Restricted; Dilt | 1986 |
A physico-chemical comparison of aortic receptors in rat hypertension models.
Topics: Aldosterone; Animals; Aorta; Binding Sites; Chromatography, DEAE-Cellulose; Hypertension; Male; Musc | 1986 |
[Changes in sodium metabolism in essential hypertension patients].
Topics: Adult; Aldosterone; Blood Volume; Cardiac Output; Female; Humans; Hypertension; Male; Middle Aged; P | 1986 |
Reversal of changes in metabolism and calcium sensitivity in aortas of rats recovered from aldosterone-salt hypertension.
Topics: Aldosterone; Animals; Aorta, Thoracic; Calcium; Energy Metabolism; Hypertension; Rats; Rats, Inbred | 1986 |
[Diagnostic possibilities of MR-tomography of the adrenals of patients with essential hypertension].
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hypertension; Magnetic Resonance Spectr | 1986 |
The effects of 19-nor-aldosterone on blood pressure of adrenalectomized spontaneously hypertensive rats.
Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Hypertension; Rats; Rats, Inbred SHR; Rats, Inb | 1985 |
Dopaminergic regulation of plasma aldosterone secretion in hypertensive patients.
Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Re | 1985 |
Urinary free 19-nor-deoxycorticosterone and deoxycorticosterone in human hypertension.
Topics: Adult; Aged; Aldosterone; Desoxycorticosterone; Diet, Sodium-Restricted; Female; Humans; Hypertensio | 1985 |
Dopamine reduces aldosterone and 18-hydroxycorticosterone response to angiotensin II in patients with essential low-renin hypertension and idiopathic hyperaldosteronism.
Topics: 18-Hydroxycorticosterone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Corticosterone; Depres | 1985 |
[Tetanic spasms, arterial hypertension and hypokalemia].
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Female; Humans; Hypertension | 1985 |
Calcium metabolism and parathyroid function in primary aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Blood Pressure; Calcium; | 1985 |
Salt-induced hypertension in the 'Sabra' rat strain: influence of nifedipine treatment.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Hypertension; Male; Myocardium; Nifedipine; Organ | 1985 |
[Plasma renin activity, plasma aldosterone concentration in the differential diagnosis of curable forms of secondary hypertension].
Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Angiotensin II; Diagnosis, Differential; Humans; Hyper | 1985 |
Aldosterone response to modulation of potassium in patients on dialysis or with essential hypertension.
Topics: Adult; Aldosterone; Glucose; Humans; Hydrocortisone; Hypertension; Insulin; Potassium; Renal Dialysi | 1985 |
High prevalence of cardiovascular diseases and enhanced activity of the renin-angiotensin system in psoriatic patients.
Topics: Aldosterone; Cardiovascular Diseases; Coronary Disease; Diabetes Mellitus; Humans; Hypercholesterole | 1985 |
Body-sodium and blood volume in a patient with licorice-induced hypertension.
Topics: Aged; Aldosterone; Blood Volume; Diagnosis, Differential; Glycyrrhetinic Acid; Glycyrrhiza; Glycyrrh | 1985 |
Effects of orally administered glandular kallikrein on urinary kallikrein and prostaglandin excretion, plasma immunoreactive prostanoids and platelet aggregation in essential hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Kall | 1985 |
Captopril before and after spironolactone therapy in primary aldosteronism. Pathogenetic and therapeutical aspects.
Topics: Aldosterone; Blood Pressure; Captopril; Drug Therapy, Combination; Humans; Hypertension; Potassium; | 1985 |
Is the antihypertensive effect of muzolimine due to volume depletion?
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Volume; Chronic Disease; Creatini | 1985 |
Aldosterone studies in obese patients with hypertension.
Topics: Aldosterone; Blood Pressure; Body Weight; Diet, Reducing; Humans; Hypertension; Natriuresis; Obesity | 1985 |
The state of the renin-angiotensin-aldosterone system in various clinical forms of hypertension in aging.
Topics: Adult; Aged; Aging; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angio | 1985 |
[Hypertension in the elderly: pathophysiological comparison between subjects with sustained hypertension and with transient hypertension on admission].
Topics: Aged; Aldosterone; Female; Hospitalization; Humans; Hypertension; Male; Middle Aged; Patient Admissi | 1985 |
[Clinical evaluation of penbutolol (Hoe 893d) (beta adrenergic blocker), alone and in combination with hydrochlorothiazide, in the treatment of arterial hypertension. II. Effect on plasma electrolytes, renal function, plasma renin and aldosterone activity
Topics: Aldosterone; Antihypertensive Agents; Drug Therapy, Combination; Electrolytes; Humans; Hydrochloroth | 1985 |
Effect of a calcium antagonist: verapamil on resting blood pressure and pressor response to dynamic exercise.
Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Female; Heart Rate; Humans; Hypertension; Male; | 1985 |
Urinary excretion of kallikrein before and after operation for aldosterone-producing adenoma.
Topics: Adenoma; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Kallikreins; Male; Mi | 1985 |
Essential hypertension: a metabolic cause? A hypothesis.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Calcium; Captopril; Female; Humans; Hydrochlorothiazide; H | 1985 |
Morphological changes in the adrenal cortex in different variants of low-renin hyperaldosteronism. Comparison with the functional state of certain hormonal systems.
Topics: Adenoma; Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Hu | 1985 |
[Results of the surgical management of primary aldosteronism based on a retrospective analysis of preoperative diagnosis and morphology of the adrenal gland].
Topics: Adrenal Glands; Adrenalectomy; Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Corticosterone | 1985 |
Resistance to captopril in hypertension of coarctation of the aorta.
Topics: Adult; Aldosterone; Aortic Coarctation; Captopril; Drug Resistance; Humans; Hypertension; Middle Age | 1985 |
A study of urinary sodium and potassium excretion rates among urban and rural Zulus and Indians.
Topics: Adult; Age Factors; Aldosterone; Black People; Blood Pressure; Female; Humans; Hypertension; Kinetic | 1985 |
[Changes in reactivity of the renin-angiotensin-aldosterone system in old age as a risk factor in the development of hypertension].
Topics: Adult; Aged; Aging; Aldosterone; Angiotensin II; Homeostasis; Humans; Hypertension; Hypothalamo-Hypo | 1985 |
[Role of hormonal factors in the etiology of juvenile arterial hypertension].
Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Hormones; Humans; Hydrocortisone; Hypertension; Male | 1985 |
Head out water immersion (WI) induced endocrine alterations in hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Immersion; Plasma Volume; Renin; Vasopress | 1985 |
Is the renin-angiotensin-aldosterone system (RAAS) related to vasopressin (AVP) secretion in patients with essential hypertension.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Male; Renin; Renin-Angiotensin System; Vasopressin | 1985 |
Adrenalectomy in primary aldosteronism: a long-term follow-up study.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Blo | 1985 |
Pathogenetic aspects of hypertension in Cushing's syndrome.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensinogen; Blood Pressure; Child; Circadian Rhythm; Cush | 1985 |
Effects of san-huang-hsieh-hsin-tang on sympathetic activity, plasma renin, and plasma aldosterone.
Topics: Aldosterone; Humans; Hypertension; Medicine, Chinese Traditional; Medicine, East Asian Traditional; | 1985 |
Clinical evaluation of the captopril screening test for primary aldosteronism.
Topics: Adult; Aldosterone; Captopril; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal | 1985 |
Two possible mechanisms for alcohol associated hypertension.
Topics: Adult; Alcohol Drinking; Alcoholism; Aldosterone; Blood Pressure; Double-Blind Method; Ethanol; Huma | 1985 |
Alcohol withdrawal and hypertension: evidence for a kidney abnormality.
Topics: Alcoholism; Aldosterone; Humans; Hydrocortisone; Hypertension; Kidney; Natriuresis; Renin; Substance | 1985 |
Effects of diltiazem on hormonal and hemodynamic responses to lower body negative pressure and tilt in patients with mild to moderate systemic hypertension.
Topics: Adult; Aged; Aldosterone; Benzazepines; Blood Pressure; Diltiazem; Forearm; Heart Rate; Hemodynamics | 1985 |
Angiotensin-induced hypertension in conscious dogs: biochemical parameters and baroreceptor reflex.
Topics: Aldosterone; Angiotensin II; Animals; Body Weight; Consciousness; Disease Models, Animal; Dogs; Fema | 1985 |
The diagnostic value of the 24 hour integrated concentration of plasma aldosterone.
Topics: Adolescent; Adult; Aged; Aldosterone; Analysis of Variance; Child; Diagnosis, Differential; Evaluati | 1985 |
Cardiovascular, baroreflex and humoral responses in hypertensive patients during nicardipine therapy.
Topics: Adult; Aldosterone; Carotid Arteries; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle A | 1985 |
[Studies on the pathophysiology of pregnancy induced hypertension--endocrinological analysis by the method of angiotensin II and NaCl loading].
Topics: Aldosterone; Angiotensin II; Bradykinin; Female; Humans; Hypertension; Kallikreins; Pregnancy; Pregn | 1985 |
[Central hemodynamic function and the metabolic electrolyte ratio of patients with hypertension and hereditary disposition].
Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Catecholamines; Chronic Disease; Disease Susceptibility | 1985 |
Body sodium-blood volume state, aldosterone, and cardiovascular responsiveness after calcium entry blockade with nifedipine.
Topics: Aged; Aldosterone; Angiotensin II; Blood Volume; Calcium; Chlorthalidone; Drug Therapy, Combination; | 1985 |
The role of urinary kininogen in the regulation of kinin generation.
Topics: Aldosterone; Blood Pressure; Creatinine; Diuresis; Humans; Hypertension; Kallikreins; Kidney Failure | 1985 |
The contribution of arterial pressure to the cardiac dysfunction of chronic alcoholism.
Topics: Adult; Alcoholism; Aldosterone; Blood Pressure; Catecholamines; Echocardiography; Electrolytes; Hear | 1985 |
[Concentration of somatotropic hormone in the blood in arterial hypertension of different origin].
Topics: Adult; Aldosterone; Climacteric; Female; Growth Hormone; Hemodynamics; Humans; Hypertension; Hyperte | 1985 |
Hemodynamic, renal, and hormonal responses to changes in dietary potassium in normotensive and hypertensive man: long-term antihypertensive effect of potassium supplementation in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Creatinine; Diet, Sodium-Restricted; Epinephrine; Female; Hormon | 1985 |
[Acute effect of nifedipine on arterial pressure and the renin-angiotensin system in healthy subjects and hypertensives].
Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male | 1985 |
Intracerebroventricular infusion of aldosterone induces hypertension in rats.
Topics: Aldosterone; Animals; Brain; Cerebral Ventricles; Hypertension; Male; Mineralocorticoid Receptor Ant | 1986 |
Dopaminergic modulation of salt sensitivity in patients with essential hypertension.
Topics: Aged; Aldosterone; Blood Pressure; Dopamine; Dopamine Antagonists; Epinephrine; Female; Humans; Hype | 1986 |
Alterations in active Na-K transport during mineralocorticoid-salt hypertension in the rat.
Topics: Aldosterone; Animals; Biological Transport, Active; Chlorides; Desoxycorticosterone; Hypertension; K | 1986 |
The prediction of anatomical morphology of primary aldosteronism using serum 18-hydroxycorticosterone levels.
Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Corticoster | 1985 |
Calcium sensitivity of isometric force in intact and chemically skinned aortas during the development of aldosterone-salt hypertension in the rat.
Topics: Aldosterone; Animals; Biological Transport; Blood Pressure; Calcium; Hypertension; Rats | 1985 |
Clinical significance of unconjugated 3 alpha,5 beta-tetrahydroaldosterone and 5 beta-dihydroaldosterone measured by radioimmunoassay.
Topics: Aldosterone; Chromatography, Paper; Female; Humans; Hypertension; Male; Radioimmunoassay | 1985 |
[Therapy resistant hypertension].
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Female; Humans; Hypertension; Middle Aged; Neoplasms, | 1985 |
Plasma immunoreactive gamma melanotropin in patients with idiopathic hyperaldosteronism, aldosterone-producing adenomas, and essential hypertension.
Topics: Adenoma; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Melanocyte-Stim | 1985 |
The second Sir George Pickering memorial lecture. What regulates whole body autoregulation? Clinical observations.
Topics: Adult; Aldosterone; Autonomic Nervous System Diseases; Blood Pressure; Body Fluids; Cardiac Output; | 1985 |
Antihypertensive effect of riboflavin analogues in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Antihypertensive Agents; Flavins; Hydrochlorothiazide; Hypertension; Male; Min | 1985 |
Sodium-dependent hypertension produced by chronic central angiotensin II infusion.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Water; Drinking; Heart Rat | 1985 |
Diagnostic imaging in hypertension.
Topics: Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension; Hypertension, Renovascular; Urography | 1985 |
Atrial natriuretic factor: isolation, identification, biological and pharmacological actions.
Topics: Aldosterone; Amino Acid Sequence; Animals; Blood Vessels; Heart Atria; Hypertension; Myocardium; Nat | 1985 |
21-Deoxytetrahydroaldosterone excretion in primary hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hyperplas | 1985 |
Selective blood sampling in adrenal hypertension.
Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Aldosterone; Cushing Syndrome; Epinephrine; | 1985 |
Nicardipine and nifedipine: effects on diuresis and serum aldosterone levels in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Diuresis; Hypertension; Male; Nicardipine; Nifedipine; Rats; R | 1985 |
[Serum aldosterone level in patients with hypertension during treatment by acupuncture].
Topics: Acupuncture Therapy; Adult; Aldosterone; Female; Follow-Up Studies; Humans; Hyperaldosteronism; Hype | 1985 |
Hypertension in hypothyroidism: arterial pressure and hormone relationships.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Epinephrine; Female; Heart Rate; Humans; Hype | 1985 |
Hypertension with aldosterone excess and low plasma-renin: preoperative distinction between patients with and without adrenocortical tumour.
Topics: Adenoma; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Age Fac | 1970 |
Apparently isolated excess deoxycorticosterone in hypertension. A variant of the mineralocorticoid-excess syndrome.
Topics: 17-Ketosteroids; Adult; Aged; Aldosterone; Chromatography, Gas; Desoxycorticosterone; Dexamethasone; | 1972 |
Plasma renin, renin substrate, angiotensin II, and aldosterone in hypertensive disease of pregnancy.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Estrogens; Female; Gestational Age; Humans; Hypertensio | 1973 |
Plasma-aldosterone during oral-contraceptive therapy.
Topics: Acetates; Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Contraceptive | 1973 |
Mineralocorticoids and rectal potential difference.
Topics: Aldosterone; Biological Transport, Active; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Me | 1973 |
Editorial: Sodium and the pressor role of angiotensin.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Hypertension, | 1973 |
Body-fluid volume in low-renin hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Body Height; Body Surface Area; Body Weight; Extracellular Space | 1974 |
Renin and hypertension in childhood.
Topics: Aldosterone; Alpha-Globulins; Angiotensin II; Child; Child, Preschool; Humans; Hypertension; Hyperte | 1974 |
Proceedings: Mode of action of beta-adrenergic receptor blocking drugs in hypertension.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Brain; Cardiac Output; Humans; Hypertensio | 1974 |
Sympathectomy for hypertension.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Diuretics; Guanethidine; Humans; Hypertens | 1974 |
[Neurohumoral aspects of myocardial infarct and its complications].
Topics: 17-Ketosteroids; Adrenal Glands; Adult; Aged; Aldosterone; Epinephrine; Female; Heart Failure; Hemod | 1974 |
[Essential hypertension: Renin and aldosterone, key to pathogeny and therapy?].
Topics: Adrenergic beta-Antagonists; Aldosterone; Autonomic Nervous System; Blood Volume; Diuretics; Hemodyn | 1974 |
The influence of a heparin-like compound on hypertension, electrolytes and aldosterone in man.
Topics: Adult; Aldosterone; Blood; Electrolytes; Ephedrine; Heparinoids; Humans; Hypertension; Middle Aged; | 1966 |
Renin and angiotensin.
Topics: Addison Disease; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Kidney; Potassiu | 1968 |
Clinical investigation of the effects of adrenal corticosteroid excess on the colon.
Topics: Addison Disease; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Adult; Aldosterone; Colon; C | 1969 |
Possible mechanism of action for aldosterone-induced hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Carotid Sinus; Humans; Hyperaldosteronism; Hypertension; Hyper | 1970 |
The influence of a heparin-like compound on hypertension, electrolytes and aldosterone in man.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aldosterone; Blood Pressure; Female; Glycosaminoglycans; | 1966 |
Co-existing aldosterone-producing adrenal tumor (aldosteronoma) and bilateral renovascular lesions.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Angiography; Blood Pressure; Carbon Di | 1969 |
Essential hypertension: renin and aldosterone, heart attack and stroke.
Topics: Adult; Aldosterone; Cardiomegaly; Cerebrovascular Disorders; Female; Humans; Hypertension; Male; Mid | 1972 |
Excretion of conjugated 11-deoxy-17-ketosteroids in "essential" hypertension.
Topics: 17-Ketosteroids; Adult; Age Factors; Aged; Aldosterone; Androstenes; Androsterone; Blood Pressure; C | 1972 |
The vascular reactivity to vasoactive substances and the electrolyte contents in arterial walls.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Arteries; Blood Pressure; Carbon Tetrachloride | 1965 |
[Studies on the renin-angiotensin-aldosterone system, especially their roles in the humoral regulating system and the cause of hypertension].
Topics: Aldosterone; Angiotensin II; Animals; Dogs; Hypertension; Rats; Renin | 1965 |
On the role of renin-angiotensin system with special relation to aldosterone for the etiology of hypertension.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood; Hyperaldosteronism; Hypertension; In Vit | 1966 |
On the humoral factors in arterial hypertension.
Topics: Aldosterone; Angiotensin II; Blood; Humans; Hypertension; Renin; Urine | 1966 |
[Behavior of urinary aldosterone and electrolytes during infusion of angiotensin II in normal, essential and renovascular hypertensive subjects].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; In Vitro Techniques; Male; Urine; | 1965 |
[Aldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Animals; Edema; Female; Humans | 1965 |
[Angiotensin intradermoreaction in patients with liver cirrhosis in the ascitic phase. Results and interpretation in relation to the pathogenesis of the altered hydrosaline metabolism in cirrhogenic liver diseases].
Topics: Aldosterone; Angiotensin II; Ascites; Diabetes Insipidus; Heart Failure; Humans; Hypertension; Jaund | 1966 |
Renal renin in unilaterally nephrectomized hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Female; Hypertension; Juxtaglomerular Apparatus; Kidney; Kidne | 1965 |
[Study on corticosterone secretion rate with reference to normal and hypertensive subjects].
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Aldosterone; Body Constitut | 1966 |
Renin-angiotensin-aldosterone system during chronic thiazide therapy of benign hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hydrochlorothiazide; Hypertens | 1968 |
Effect of corticotropin on aldosterone excretion and plasma renin in normal subjects, in essential hypertension and in primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angioten | 1968 |
Effects of glucocorticoid administration on aldosterone excretion and plasma renin in normal subjects, in essential hypertension and in primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Dexameth | 1968 |
[Renin and aldosterone in human arterial hypertension (excluding Conn's syndrome)].
Topics: Adult; Aldosterone; Angiotensin II; Diagnosis, Differential; Diet, Sodium-Restricted; Female; Humans | 1965 |
[Aldosteronuria in the hypertensive patient with Addison's disease].
Topics: Addison Disease; Adrenocorticotropic Hormone; Aged; Aldosterone; Angiotensin II; Female; Humans; Hyp | 1968 |
[Influence of experimental sodium chloride depletion on water-electrolyte metabolism, blood pressure and reaction ability of the vascula system in young hypertonics].
Topics: Adult; Age Factors; Aldosterone; Angiotensin II; Blood Vessels; Electrolytes; Erythrocytes; Female; | 1968 |
[The reinin- angiotensin-aldosterone system in essential and renovascular hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypertension, Renal; Juxtaglomerul | 1968 |
Aldosterone production after suppression of corticotropic secretory activity.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Depression, Chemical; Dexamethasone; Diet, | 1968 |
[Data on the further study of the etiology and pathogenesis of hypertension].
Topics: Adrenocortical Hyperfunction; Aldosterone; Animals; Bradykinin; Brain; Carotid Sinus; Dogs; Endopept | 1967 |
Suppressed plasma renin activity in hypertension.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldostero | 1969 |
[The renin, angiotensin and aldosterone system in secondary hypertension].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin | 1968 |
Studies of hypertension and carbohydrate intolerance associated with Wilms tumor.
Topics: Aldosterone; Carbohydrate Metabolism; Female; Glucose Tolerance Test; Humans; Hypertension; Hypokale | 1969 |
Relation of the pituitary to the sodium-retaining effects of adrenal enucleation.
Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Animals; Glucocorticoids; H | 1969 |
Studies of plasma renin activity in patients with hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Diagnosis, Differential; Diet, Sodium-Restricted; Female; Humans | 1968 |
[Does the recent knowledge on the renin-angiotensin system have clinical applications?].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Feedback; Humans; Hyperaldosteronism; Hypertension; Jux | 1968 |
[Determination of renin activity and aldosteronuria in 24 hypertensives].
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hype | 1968 |
[Renin and angiotensin].
Topics: Aldosterone; Angiotensin II; Animals; Arteries; Dogs; Humans; Hypertension; Hypertension, Renal; Jux | 1968 |
Medical grand rounds from the University of Alabama Medical Center.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertens | 1969 |
[Dynamic tests of the function of the renin-angiotensin-aldosterone system].
Topics: Adrenal Insufficiency; Aldosterone; Angiotensin II; Diagnosis, Differential; Diazoxide; Diet, Sodium | 1969 |
[Plasma renin activity in peripheral venous blood under various stimulation conditions].
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Arteriosclerosis; Blood Pressure; Creat | 1969 |
Quantitative analysis of the pathophysiology of hypertension.
Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Blood Pressure; Blood Vessels; Cardiac Output | 1969 |
Hypertension with inappropriate aldosterone stimulation.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II | 1969 |
[Study on the renin-angiotensin-aldosterone system. Effects of sodium restriction and postural changes on plasma renin activity and fluctuation in urinary aldosterone].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Chromatography, Thin Layer; Diet, Sodium-Restricted; Hu | 1969 |
The renin-angiotensin system in curable hypertension.
Topics: Aldosterone; Angiotensin II; Chemical Phenomena; Chemistry; Feedback; Humans; Hypertension; Renin | 1969 |
Studies of the renin-angiotensin-aldosterone system in patients with hypertension and in normal subjects.
Topics: Aldosterone; Angiotensin II; Blood Urea Nitrogen; Body Weight; Creatinine; Diet; Diet, Sodium-Restri | 1969 |
Renin-angiotensin-aldosterone system in hypertension. The clinical usefulness of measuring components of thisystem.
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Renin | 1969 |
Hypermineralocorticoid-induced hypertension.
Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldosterone; Desoxycorticosterone; Humans | 1969 |
Corticosteroid synthesis in adrenal enucleated rats before the onset of hypertension.
Topics: Adrenal Glands; Adrenal Medulla; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Animals; B | 1969 |
Hyperaldosteronism in hypertensive congenital adrenal hyperplasia.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenal Rest Tumor; Adr | 1969 |
[Arterial hypertension and inadequate stimulation of aldosterone secretion. A new syndrome].
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Corticosterone; Diet, Sodium-Restricted; H | 1969 |
Primary aldosteronism in a hypertensive acromegalic patient.
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone | 1969 |
[Hypertension and endocrinology].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Angiotensin II; Catecholamines; Cushi | 1969 |
Suppressed plasma renin activity in essential hypertension. Roles of plasma volume, blood pressure, and sympathetic nervous system.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Catecholamines; Diet; Epinephrine; | 1970 |
Abnormal responsiveness of the renin aldosterone system to acute stimulation in patients with essential hypertension.
Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Bloodletting; Diuretics | 1970 |
Aldosteronism in hypertensive disease.
Topics: Adrenal Gland Diseases; Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Potas | 1970 |
[A case of arterial hypertension imputable to an estroprogestational contraceptive. Implication of the renin-angiotensin-aldosterone system].
Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Estrogens; Female; Humans; Hyperaldosteron | 1969 |
Aldosterone, angiotensin, and hypertension.
Topics: Aldosterone; Angiotensin II; Humans; Hypertension | 1970 |
Hypertension in young females receiving anovulatory steroids.
Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Drug Hypersensitivity; Female; Humans; Hyp | 1970 |
The pathophysiology and bio-assay of the renin-angiotensin system.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Biological Assay; Child; Child, Preschool; Female; H | 1970 |
Adrenal cortex, aldosterone, and hypertension. Report of an international workshop.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Female; Humans; Hypertension; Methods; Posture | 1969 |
Abnormally sustained aldosterone secretion during salt loading in patients with various forms of benign hypertension; relation to plasma renin activity.
Topics: Adolescent; Adrenocortical Hyperfunction; Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; | 1970 |
The influence of potassium administration and of potassium deprivation on plasma renin in normal and hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin II; Biological Transport, Active; Blood Pressure; Diet Therapy; Fema | 1970 |
[Endocrine hypertension].
Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Aldosterone; | 1970 |
[Importance of renin-angiotensin-aldosterone system in diverse forms of hypertension].
Topics: Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Animals; Contraceptives, Oral; Female; Humans; | 1970 |
The pill, hypertension, and the toxemias of pregnancy.
Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Edema; Estrogens; Female; Humans; Hypernatremia; | 1971 |
Hypertension, oral contraceptive agents, and conjugated estrogens.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Determination; Contraceptives, Or | 1971 |
The etiopathology of hypertension.
Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Cardiac | 1970 |
A quantitative approach to the study of circulatory abnormality, especially of hypertension.
Topics: Aldosterone; Angiotensin II; Arteries; Blood Pressure; Body Fluids; Humans; Hypertension; Kidney; Pr | 1971 |
[Clarification of a hypertension].
Topics: Aldosterone; Angiotensin II; Aortic Coarctation; Blood Pressure Determination; Creatinine; Cushing S | 1970 |
[Oral contraceptives and hypertension].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Estrogens; Female; Humans; Hypert | 1971 |
On the role of aldosterone to hypertension, especially an extent of its participation.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Animals; Blood Pressure; Femal | 1971 |
The role of aldosterone in pathogenesis of arterial hypertension.
Topics: Addison Disease; Aldosterone; Angiotensin II; Animals; Arteries; Cushing Syndrome; Fundus Oculi; Hum | 1971 |
Discussion on pathogenesis of hypertension.
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Potassium; Renin; Sodium | 1971 |
Determination of plasma renin concentration by angiotensin I immunoassay. Diagnotic import of precise measurement of subnormal renin in hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Hyperfunction; Aldos | 1971 |
[Relationship between the renin-angiotensin-aldosterone system and CNS in the etiology of hypertension].
Topics: Aldosterone; Angiotensin II; Central Nervous System; Humans; Hypertension; Renin; Sympathetic Nervou | 1971 |
Abnormal membrane sodium transport in Liddle's syndrome.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Biological Transport; Cell Membrane; Child; Erythroc | 1971 |
[Comparative gas chromatographic analysis of the FFA-pattern in the plasma in different models of hypertension in the rat].
Topics: Aldosterone; Angiotensin II; Animals; Chromatography, Gas; Disease Models, Animal; Fatty Acids, None | 1971 |
[Relation of plasma renin activity and aldosterone excretion rate in angiotensin II-test and its diagnostic value in arterial hypertension patients].
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Methods; Renin; Water-Electrolyte B | 1971 |
[Clinical studies on the relation between aldosterone and various hypertensive and renal diseases. 2. Studies on the effect of synthetic angiotensin II on aldosterone secretion rate].
Topics: Addison Disease; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Injections, Intr | 1971 |
Plasma renin activity and aldosterone secretion in patients with acromegaly.
Topics: Acromegaly; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Chlorides; Diet, | 1972 |
[Significance of renin-angiotensin system in the development of hypertension--author's comments and viewpoint].
Topics: Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Renin | 1971 |
[The renin-angiotensin-aldosterone system. Disorders and methods of clinical research].
Topics: Adrenal Gland Neoplasms; Adrenal Insufficiency; Aldosterone; Angiotensin II; Dexamethasone; Electrol | 1970 |
Control of blood pressure.
Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Blood Pressure; Hexamethonium Compounds; Huma | 1972 |
Plasma desoxycorticosterone levels in man with simultaneous measurement of aldosterone, corticosterone, cortisol and 11-deoxycortisol.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Carbon Isotopes; Chromatography, Paper; Co | 1972 |
[Hypertension and hypertensive syndromes].
Topics: Adult; Aldosterone; Angiotensin II; Arteriosclerosis; Glomerulonephritis; Humans; Hypertension; Hype | 1971 |
Drug modification of digital vascular reactivity to vasoactive substances.
Topics: Aldosterone; Angiotensin II; Benzothiadiazines; Blood Pressure; Dihydroxyphenylalanine; Fingers; Gua | 1969 |
Arterial pressure regulation. Overriding dominance of the kidneys in long-term regulation and in hypertension.
Topics: Aldosterone; Angiotensin II; Arteries; Blood Pressure; Blood Vessels; Blood Volume; Cardiac Output; | 1972 |
Plasma cortisol and adrenocorticotrophic hormone in normal men and non-pregnant women, normal pregnant women and women with pre-eclampsia.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood; Cesarean Section; Circadian | 1972 |
Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Blood Pr | 1972 |
Low renin hypertension and the adrenal cortex.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Cor | 1972 |
Volume control.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Glomerular Filtration Rate; Hemodynamics; Humans; Hyper | 1972 |
[Kidney and hypertension].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Extracellular Space; Humans; Hypertension; Hyp | 1972 |
[Renin-angiotensin-aldosterone system in water-electrolyte homeostasis].
Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Electrolytes; Humans; Hyperaldosteronism; Hyp | 1972 |
Oral contraceptive hypertension.
Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Estrogens; Female; Humans; Hypertension; Kidney; | 1972 |
Effect of prostaglandin A 1 on renal and adrenal function in man.
Topics: Adrenal Glands; Aldosterone; Ascites; Blood Pressure; Calcium; Creatinine; Cyclic AMP; Edema; Glomer | 1972 |
The renin-angiotensin-aldosterone system in normotensive and hypertensive patients with acromegaly.
Topics: Acromegaly; Adolescent; Adult; Aldosterone; Angiotensin II; Blood Volume; Female; Growth Hormone; Hu | 1972 |
The control of aldosterone secretion in normal and hypertensive man: abnormal renin-aldosterone patterns in low renin hypertension.
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Potassium; Renin; Sodium | 1972 |
Renin, angiotensin II, and adrenal corticosteroid relationships during sodium deprivation and angiotensin infusion in normotensive and hypertensive man.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Corticosterone; Female; | 1972 |
[Hemodialysis and hypertension].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Kidney Failure, Chronic; Renal Dialysis; Renin | 1972 |
Accelerated hypertension secondary to oral contraceptives.
Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Estrogens; Female; Humans; Hypertension; Renin | 1973 |
[Essential hypertension: biochemical analysis--selective treatment].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Propranolol; Renin; Sodium | 1973 |
Effects of ACTH and salt on blood pressure and steroid secretion in rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure; Corticosterone; D | 1972 |
Plasma volume, extracellular fluid volume and exchangeable sodium concentrations in the New Zealand strain of genetically hypertensive rat.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Chromium Isotopes; Extracellular | 1973 |
Angiotensin, aldosterone and DOC in hypertensive disease of pregnancy.
Topics: Aldosterone; Angiotensin II; Desoxycorticosterone; Female; Humans; Hypertension; Pregnancy; Pregnanc | 1973 |
Hypertension with adrenal, genital, renal defects, and deafness. A new familial syndrome.
Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Aldosterone; Deafness; Female; Glucocort | 1973 |
[Arterial hypertension and mineralocorticoids].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Cortisone; Cushing Syndrome; Female | 1973 |
[Oral contraceptives and hypertension].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Female; Humans; Hypertension; Ren | 1973 |
Time course of decrease in blood pressure and in blood pressure response to vasopressor agents during pregnancy in the rat.
Topics: Acetylcholine; Aldosterone; Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Female; H | 1973 |
[Renin-angiotensin-aldosterone system in hyperthyroidism].
Topics: Aldosterone; Angiotensin II; Female; Furosemide; Humans; Hypertension; Hyperthyroidism; Hypopituitar | 1973 |
Editorial: New knowledge of benign essential hypertension.
Topics: Age Factors; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Ethnicity; Humans | 1973 |
Vasoconstriction-volume analysis for understanding and treating hypertension: the use of renin and aldosterone profiles.
Topics: Aldosterone; Angiotensin II; Arteries; Blood Pressure; Diuretics; Humans; Hyperaldosteronism; Hypert | 1973 |
The renin axis in causation, prognosis and treatment of hypertensive disease.
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Prognosis; Renin | 1973 |
Clinical conference: Essential hypertension: new concepts about mechanisms.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Humans; Hydroxycorticos | 1973 |
Altered ion transport in vascular smooth muscle from spontaneously hypertensive rats. Influences of aldosterone, norepinephrine, and angiotensin.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Aorta; Aorta, Thoracic; Blood Pressure; Chlorid | 1973 |
Proceedings: Blueprints for the solution of three endocrinological enigmas. The Sir Henry Dale Lecture for 1973.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Blood Glucose; Ca | 1973 |
Renin-secreting Wilms' tumor with severe hypertension. Report of a case and brief review of renin-secreting tumors.
Topics: Aldosterone; Child, Preschool; Diagnosis, Differential; Humans; Hypertension; Kidney; Kidney Neoplas | 1973 |
Systems analysis of arterial pressure regulation and hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Arteries; Blood Pressure; Capillary Permeability; Cardiac Outp | 1972 |
Renal function in pregnancy.
Topics: Aldosterone; Angiotensin II; Catecholamines; Estrogens; Female; Glomerular Filtration Rate; Glycosur | 1972 |
[Water and electrolyte imbalance and the renin-angiotensin-aldosterone system].
Topics: Aldosterone; Angiotensin II; Animals; Dogs; Electrolytes; Humans; Hypertension; Male; Middle Aged; P | 1973 |
[Pregnancy toxemia. Recent data].
Topics: Aldosterone; Angiotensin II; Disseminated Intravascular Coagulation; Estriol; Female; Fetal Death; F | 1974 |
Hormonal profiling in the diagnosis and treatment of essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Female; Humans; Hyperaldosteronism; Hypert | 1974 |
[Recent contributions to the study of arterial hypertension].
Topics: Aldosterone; Angiotensin II; Endopeptidases; Humans; Hypertension; Hypertension, Malignant; Renin | 1974 |
Plasma renin concentration: comparison of angiotensinase inhibitors and correlation with plasma renin activity and aldosterone.
Topics: Aldosterone; Angiotensin II; Dimercaprol; Humans; Hydrogen-Ion Concentration; Hypertension; Methods; | 1974 |
[Diagnosis and therapy of arterial hypertension. Significance of the renin-angiotensin-aldosterone system in differential diagnosis and therapy].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Antihypertensive Agents; Diagnosis, Differential; Human | 1974 |
Mineralocorticoid receptors in salt-susceptible and salt-resistant rats.
Topics: Aldosterone; Animals; Binding, Competitive; Cell Nucleus; Cytoplasm; Desoxycorticosterone; Female; H | 1974 |
[The evaluation of arterial hypertension (author's transl)].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Blood Sedimentation; Electrocardiography; Humans; Hyper | 1974 |
Response of plasma aldosterone to postural change, diuretica, angiotensin II, sodium restriction or loading and prostaglandin.
Topics: Adrenocortical Hyperfunction; Aldosterone; Angiotensin II; Ascites; Cushing Syndrome; Diet; Diet, So | 1973 |
[Primary and secondary aldosteronism in hypertension].
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hype | 1974 |
[Prognosis of hypertension disease and of the system renin-angiotension-aldosteron (author's transl)].
Topics: Aldosterone; Angiotensin II; Arteries; Humans; Hydrocortisone; Hypertension; Prognosis; Radioimmunoa | 1974 |
Plasma aldosterone during haemodialysis in patients with terminal renal failure.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Humans; Hydrocortisone; Hy | 1973 |
Decreased response of plasma renin activity to orthostasis in diabetic patients with orthostatic hypotension.
Topics: Adult; Aldosterone; Amyloidosis; Angiotensin II; Animals; Blood Pressure; Cattle; Diabetes Complicat | 1974 |
[Exchangeable sodium and sodium space in some types of hypertension (author's transl)].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Renin; Sodium | 1974 |
Clinical use of renin determinations.
Topics: Aldosterone; Angiotensin II; Blood Volume; Feedback; Humans; Hypertension; Hypertension, Renal; Meth | 1974 |
An angiotensin converting-enzyme inhibitor to identify and treat vasoconstrictor and volume factors in hypertensive patients.
Topics: Adolescent; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; B | 1974 |
Editorial: Angiotensin inhibition.
Topics: Alanine; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Press | 1974 |
Low renin, "normal" aldosterone and hypertension: circadian rhythm of renin, aldosterone, cortisol and growth hormone.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Circadian Rhythm; Female; Growth Hormone; Humans; H | 1974 |
Renin and hypertension.
Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Humans; Hyperaldosteronism; Hypertension; Hype | 1973 |
The adrenal cortex and the kidney.
Topics: Adrenal Cortex; Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Al | 1974 |
[The effect of oral contraceptives on plasma renin activity and plasma renin substrate concentration (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Drug Combinations; Ethinyl Estradiol; Feed | 1974 |
Some observations on arterial and venous levels of angiotensin II in man.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Creatinine; Female; Humans; Hypertension; Iodine Rad | 1974 |
The prevalence of hypertension in an unselected population, and the frequency of abnormalities of potassium, angiotensin II and aldosterone in hypertensive subjects.
Topics: Aldosterone; Angiotensin II; Female; Health Surveys; Humans; Hypertension; Hypokalemia; Male; Middle | 1974 |
[Experimental perspectives on the pathogenesis of essential arterial hypertension].
Topics: Aldosterone; Angiotensin II; Animals; Anxiety; Blood Coagulation; Epinephrine; Fibrinolysis; Heart R | 1974 |
[Proceedings: Plasma aldosterone response to angiotensin injection in essential hypertension and various other diseases].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension | 1974 |
[Arterial hypertension (author's transl)].
Topics: Aldosterone; Angiotensin II; Epinephrine; Humans; Hypertension; Mineralocorticoids; Norepinephrine; | 1974 |
Renin-aldosterone axis in renal transplant patients.
Topics: Adult; Aldosterone; Angiotensin II; Female; Graft Rejection; Humans; Hypertension; Hypertension, Mal | 1974 |
Treatment of essential hypertension with a new vasodilator in combination with beta-adrenergic blockade.
Topics: Adrenergic alpha-Antagonists; Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Cardiac O | 1970 |
[Nephrologic aspects of late gestosis (author's transl)].
Topics: Aldosterone; Edema; Female; Hemodynamics; Humans; Hypertension; Kidney Diseases; Pre-Eclampsia; Preg | 1974 |
[Quantitative determination of aldosterone in the urine of patients with hypertension].
Topics: Adolescent; Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged | 1974 |
Proceedings: Plasma renin activity and aldosterone concentration in children.
Topics: Age Factors; Aldosterone; Child; Child, Preschool; Humans; Hypertension; Infant; Radioimmunoassay; R | 1974 |
Urinary kallikrein excretion in hypertensive man. Relationships to sodium intake and sodium-retaining steroids.
Topics: Adult; Aldosterone; Blood Pressure; Diet; Diet, Sodium-Restricted; Fludrocortisone; Humans; Hyperald | 1974 |
Plasma aldosterone in essential hypertension with low renin activity.
Topics: Aldosterone; Body Weight; Corticosterone; Cushing Syndrome; Furosemide; Humans; Hydrochlorothiazide; | 1974 |
[Detection of 18-hydroxy-11-desoxycorticosterone and of 2 unknown substances in the urine of hypertensive patients. Isolation of one of these substances].
Topics: Aldosterone; Chromatography, Gas; Chromatography, Paper; Desoxycorticosterone; Female; Humans; Hyper | 1974 |
[Aldosterone excretion and plasma renin activity in patients with essential hypertension and with primary aldosteronism (author's transl)].
Topics: Adolescent; Adult; Aldosterone; Diet, Sodium-Restricted; Female; Humans; Hyperaldosteronism; Hyperte | 1974 |
[Behavior of plasma aldosterone following sodium reduction and sodium tolerance in primary and renal hypertension].
Topics: Aldosterone; Deficiency Diseases; Furosemide; Humans; Hypertension; Hypertension, Renal; Sodium; Sti | 1974 |
[Plasma renin activity and aldosterone excretion in patients with essential hypertension, with hypertension in bilateral adrenal cortex hyperplasia and with aldosterone-producing adrenal cortex adenomas following various sodium tolerance tests].
Topics: Adenoma; Adrenal Cortex Function Tests; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldostero | 1974 |
Altered adrenal steroidogenesis in "low renin" essential hypertension.
Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Animals; Cytosol; Depression, Chemical; Desoxycor | 1974 |
Vascular reactivity in obesity.
Topics: Adult; Aldosterone; Blood Pressure; Blood Vessels; Catecholamines; Female; Humans; Hydrocortisone; H | 1974 |
Primary aldosteronism, idiopathic aldosteronism and "low-renin" benign essential hypertension. A retrospective study.
Topics: Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Cerebrovascular Disorders; Female; Humans; Hy | 1974 |
[Proceedings: Plasma aldosterone and 11-deoxycorticosterone (DOC) in normal subjects, endocrinopathic hypertension and essential hypertension].
Topics: Adult; Aldosterone; Corticosterone; Endocrine System Diseases; Female; Humans; Hypertension; Male; M | 1974 |
[Proceedings: Hypertension--correlation between chronological changes of plasma renin activity and aldosterone levels in spontaneous hypertension in rats].
Topics: Aldosterone; Animals; Hypertension; Rats; Renin | 1974 |
[Proceedings: Quantification of aldosterone secretion in various types of hypertension (by radioimmunoassay)].
Topics: Aldosterone; Humans; Hypertension; Radioimmunoassay | 1974 |
[Proceedings: Plasma renin activity and aldosterone values in furosemide loading in various diseases].
Topics: Aldosterone; Edema; Furosemide; Humans; Hypertension; Renin | 1974 |
Management of potassium problems during long-term diuretic therapy.
Topics: Aldosterone; Diet; Diuretics; Extracellular Space; Homeostasis; Humans; Hydrogen-Ion Concentration; | 1974 |
The effect of saline infusion and postural changes on plasma aldosterone in hypertension.
Topics: Adrenal Cortex; Adrenal Glands; Aldosterone; Diagnosis, Differential; Humans; Hypertension; Hyperten | 1974 |
Antihypertensive effect of spironolactone in essential, renal and mineralocorticoid hypertension.
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Di | 1973 |
Renin suppression in hypertension in relation to body fluid volumes, patterns of sodium excretion and renal haemodynamics.
Topics: Adult; Age Factors; Aldosterone; Body Fluids; Female; Glomerular Filtration Rate; Hemodynamics; Huma | 1973 |
Selective hypoaldosteronism: a case report and review of literature.
Topics: Adrenal Insufficiency; Adult; Aldosterone; Diabetes Complications; Heart Diseases; Humans; Hyperkale | 1974 |
[Electrolytes and arterial hypertension].
Topics: Aldosterone; Animals; Desoxycorticosterone; Drug Combinations; Electrolytes; Humans; Hypertension; P | 1973 |
Possible role of 18-hydroxy-deoxycorticosterone in hypertension.
Topics: Aldosterone; Analysis of Variance; Animals; Corticosterone; Desoxycorticosterone; Diet; Female; Gene | 1972 |
[Is essential hypertension still a disease entity? Definition of hyporeninemic hypertension].
Topics: Aldosterone; Amiloride; Chlorthalidone; Diagnosis, Differential; Drug Combinations; Humans; Hydrochl | 1974 |
[Secretion, distribution, and metabolism of aldosterone in various types of hypertension].
Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Rena | 1972 |
[Quadriplegia, severe hypokalemic alkalosis, tetany, arterial hypertension in relation to excessive licorice extract consumption in a chronic alcoholic].
Topics: Alcoholism; Aldosterone; Alkalosis; Chronic Disease; Diabetes Complications; Electrocardiography; Gl | 1972 |
Adrenal adenoma and hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension | 1972 |
Experience with the use of an aldosterone antagonist in selected hypertensive patients.
Topics: Adult; Aldosterone; Carbon Dioxide; Creatinine; Female; Humans; Hypertension; Kidney Function Tests; | 1972 |
[Treatment of essential arterial hypertension with spironolactone: its value in the detection of primary hyperaldosteronism and prediction of its efficacy].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Age Factors; Aldosterone; Diet Therapy; Humans; Hyperald | 1972 |
[Pathogenesis of hypertension in primary aldosteronism].
Topics: Aldosterone; Capillary Resistance; Humans; Hyperaldosteronism; Hypertension; Potassium | 1972 |
[Radioimmunoassay of steroid hormones].
Topics: Addison Disease; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Radioimmunoass | 1972 |
Studies on essential hypertension with suppressed plasma renin activity: sodium excretion pattern on salt restriction and effects of spironolactone on blood pressure and plasma renin activity.
Topics: Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hyperaldost | 1972 |
The diagnostic and therapeutic value of spironolactone in patients with systemic hypertension.
Topics: Acid-Base Equilibrium; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Press | 1973 |
Essential hypertension--why idiopathic?
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Cardiac Outpu | 1973 |
Anomalous postural response of plasma aldosterone concentration in patients with aldosterone-producing adrenal adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; | 1973 |
A dissociated effect of amino-glutethimide on the mineralocorticoid secretion in man.
Topics: Adult; Aldosterone; Aminoglutethimide; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Dexame | 1973 |
Renin-secreting juxtaglomerular-cell adenoma. Preoperative clinical and angiographic diagnosis.
Topics: Adenoma; Adolescent; Aldosterone; Angiography; Humans; Hypertension; Kidney Neoplasms; Male; Radiogr | 1973 |
New techniques in the diagnosis and treatment of hypertension.
Topics: Aldosterone; Hypertension; Pheochromocytoma; Thyroid Neoplasms | 1973 |
Evaluation of a simplified technic for the measurement of aldosterone in human urine.
Topics: Aldosterone; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Female; Humans; Hydro | 1973 |
Primary excess and deficiency or renin.
Topics: Adolescent; Adult; Aged; Aldosterone; Child; Endocrine System Diseases; Hemangiopericytoma; Humans; | 1973 |
[Relationship between sweat, sodium and potassium excretion and the renin-angiotensin-aldosterone system in hypertension].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Child | 1973 |
Volume-dependent essential and steroid hypertension.
Topics: Adult; Aged; Aldosterone; Diet, Sodium-Restricted; Female; Follow-Up Studies; Humans; Hydrochlorothi | 1973 |
Plasma and extracellular fluid volumes in hypertension.
Topics: Aldosterone; Blood Pressure; Diuretics; Extracellular Space; Humans; Hyperaldosteronism; Hypertensio | 1973 |
Renin subgroups in essential hypertension. Further analysis of their pathophysiological and epidemiological characteristics.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aldosterone; Bicarbonates; Blood Urea Nitrogen; Diet | 1973 |
Experience with primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Female; Follow-Up Studies; Huma | 1973 |
[Studies on the autonomy of aldosterone secretion in primary hyperaldosteronism. Diagnosis and differential diagnosis of "Conn's syndrome"].
Topics: Adrenal Glands; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; M | 1973 |
Role of renin and aldosterone in hypertension due to a renin-secreting tumor.
Topics: Adrenalectomy; Adult; Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Kidney; Kidney Neo | 1973 |
Periodic hypokalaemic paralysis, adrenal adenoma, and normal colonic transport of sodium and potassium.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Colon; Corticosterone; Desoxycorticosterone; Feces; F | 1973 |
The pressor effects of application of digoxin to the carotid sinus.
Topics: Aldosterone; Animals; Blood Pressure; Carotid Sinus; Digoxin; Hypertension; Male; Rabbits | 1973 |
[Significance of hyperaldosteronism in the pathogenesis of arterial hypertension in pheochromocytoma].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aldosterone; Biopsy; Catecholamines; Chromatography, Thi | 1973 |
Diagnostic considerations in secondary hypertension.
Topics: Aldosterone; Aortic Coarctation; Contraceptives, Oral; Cushing Syndrome; Diagnosis, Differential; Hu | 1973 |
Primary amenorrhoea with hypertension due to 17-hydroxylase deficiency. Therapy with dexamethasone and ethinyloestradiol.
Topics: Adult; Aldosterone; Amenorrhea; Dexamethasone; Diet, Sodium-Restricted; Estrogens; Ethinyl Estradiol | 1973 |
Adrenocortical carcinoma with an isolated mineralocorticoid excess and recurrency fourteen years after removal of the tumor.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Humans; Hydrocortisone; Hypertension; M | 1973 |
A calcified aldosterone-producing tumor in a hypertensive, normokalemic, prepubertal girl.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Calcinosis; Child; Child Behavior Disorders; Desoxyco | 1973 |
Effect of PGA1 on renin and aldosterone in man.
Topics: 17-Hydroxycorticosteroids; Adult; Aldosterone; Blood Pressure; Body Weight; Depression, Chemical; Di | 1973 |
Antihypertensive action of propranolol. Specific antirenin responses in high and normal renin forms of essential, renal, renovascular and malignant hypertension.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Child; Female; Humans; Hypertensi | 1973 |
Volume factor in low and normal renin essential hypertension. Treatment with either spironolactone or chlorthalidone.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Chlorthalidone; Creatinine; Female; H | 1973 |
Plasma aldosterone-renin interrelationships in various forms of essential hypertension. Studies using a rapid assay of plasma aldosterone.
Topics: Adolescent; Adult; Aldosterone; Child; Diet; Female; Humans; Hypertension; Male; Methods; Middle Age | 1973 |
[Treatment of essential arterial hypertension with spironolactone: its value for the screening of primary hyperaldosteronism and prediction of its efficacy].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Probability; Spironolactone | 1973 |
[The role of anti-aldosterones in the treatment of arterial hypertension].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Potas | 1973 |
[Diagnosis of adrenal gland neoplasms causing primary aldosteronism by determination of plasma aldosterone in adrenal- or renal-vein blood].
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Child; Female; Humans; Hype | 1973 |
Hyporeninemic hypertension.
Topics: Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Renin | 1973 |
The physiology of renin secretion in essential hypertension. Estimation of renin secretion rate and renal plasma flow from peripheral and renal vein renin levels.
Topics: Aldosterone; Arteries; Blood Pressure; Humans; Hypertension; Kidney; Radiography; Regional Blood Flo | 1973 |
Editorial: Some thoughts on sodium homoeostasis.
Topics: Aldosterone; Blood Pressure; Glomerular Filtration Rate; Homeostasis; Humans; Hypertension; Kidney T | 1973 |
[Radioimmunoassay for urinary aldosterone. Aldosterone excretion in essential hypertensives (author's transl)].
Topics: Aldosterone; Buffers; Chromatography, Paper; Chromatography, Thin Layer; Cross Reactions; Humans; Hy | 1973 |
A comparison of double-isotope derivative and radioimmunological estimation of plasma aldosterone concentration in man.
Topics: Aldosterone; Carbon Radioisotopes; Female; Humans; Hypertension; Isotope Labeling; Methods; Pregnanc | 1973 |
[Humoral disorders in hypertensive disease].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Aldosterone; Catechol | 1973 |
[Role of corticosteroids in the pathogenesis of primary arterial hypertension in adolescents].
Topics: Adolescent; Adrenal Cortex Hormones; Age Factors; Aldosterone; Child; Chromatography, Thin Layer; Co | 1973 |
[The secondary disease in internal medicine (antibacterial chemotherapy)].
Topics: Aldosterone; Anti-Infective Agents; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Huma | 1973 |
Ultrastructural features of corticomedullary cells in a human adrenocortical adenoma and in rat adrenal cortex.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Animals; Catecholamines; | 1973 |
[Plasma aldosterone and plasma renin activity during hemodialysis].
Topics: Aldosterone; Humans; Hypertension; Potassium; Renal Dialysis; Renin; Time Factors | 1973 |
Radioimmunoassay of aldosterone in plasma and urine: validation of a novel separation technique and a rapid urine assay.
Topics: Aldosterone; Animals; Chromatography, Paper; Cross Reactions; Female; Furosemide; Humans; Hydrocorti | 1973 |
Actual incidence of secondary hypertension.
Topics: Adult; Aldosterone; Biopsy; Blood Pressure; Catecholamines; Cushing Syndrome; Diagnosis, Differentia | 1973 |
On the mechanism of suppressed plasma-renin activity during beta-adrenergic blockade with propranolol.
Topics: Adult; Aldosterone; Diet, Sodium-Restricted; Diuretics; Female; Humans; Hypertension; Injections, In | 1974 |
Plasma steroids in rats with experimental ectopic pituitary tumor and arterial hypertension.
Topics: Adrenal Glands; Aldosterone; Animals; Binding, Competitive; Corticosterone; Desoxycorticosterone; Hy | 1974 |
[Aldosterone excretion in patients with essential hypertension after variable sodium loading (author's transl)].
Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Radioimm | 1974 |
Mineralocorticoid receptors and 18-hydroxydeoxycorticosterone binding in the kidney of the spontaneously hypertensive rat.
Topics: Aldosterone; Animals; Binding, Competitive; Corticosterone; Cytoplasm; Dexamethasone; Female; Hypert | 1974 |
[Excretion of corticosteroids in the urine in adolescents with primary arterial hypertension].
Topics: Adrenal Cortex Hormones; Aldosterone; Corticosterone; Cortisone; Humans; Hypertension; Tetrahydrocor | 1974 |
[Aldosterone-Aldosteronism].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Male; Potassium; Sodium | 1974 |
Normal renin secretion in hypertensive patients with primarily unilateral chronic hydronephrosis.
Topics: Adult; Aged; Aldosterone; Chronic Disease; Female; Humans; Hydronephrosis; Hypertension; Hypertensio | 1974 |
[Hormonal studies in clinical aspects of internal diseases].
Topics: Adrenal Glands; Aldosterone; Epinephrine; Humans; Hyperaldosteronism; Hypertension; Norepinephrine; | 1974 |
[Endocrine hypertension syndromes of adrenal pathogenesis. II. Syndromes due to hyperaldosteronism and hypercortisolism].
Topics: Adrenocortical Hyperfunction; Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hydrocort | 1974 |
Renin, aldosterone, body fluid volumes, and the baroreceptor reflex in the development and reversal of Goldblatt hypertension in conscious dogs.
Topics: Adrenal Glands; Aldosterone; Animals; Aorta, Thoracic; Blood Pressure; Body Fluids; Denervation; Dog | 1974 |
[Anephric man].
Topics: Aldosterone; Animals; Arteries; Blood Glucose; Body Weight; Diet Therapy; Dogs; Erythropoiesis; Hema | 1968 |
[Aldosteronism. Evolution of the problem from 1955 to 1969].
Topics: Adult; Aldosterone; Diagnosis, Differential; Female; History, 20th Century; Humans; Hyperaldosteroni | 1969 |
Quadric analysis in the preoperative distinction between patients with and without adrenocortical tumors in hypertension with aldosterone excess and low plasma renin.
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Aldosterone; Bicarbonates; Blood Pr | 1971 |
The effects of sodium loading and deprivation on plasma renin and plasma and urinary aldosterone in hypertension.
Topics: Aldosterone; Corticosterone; Diet, Sodium-Restricted; Humans; Hydrocortisone; Hypertension; Potassiu | 1972 |
Hyporeninemic hypertension.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Blood Urea Nitrogen; Catecholamines; Diet, Sod | 1972 |
The 'hypertensive' evaluation.
Topics: Abdomen; Aldosterone; Auscultation; Blood Cell Count; Blood Pressure; Blood Urea Nitrogen; Catechola | 1972 |
Primary aldosteronism. Review of diagnostic tests and 15 cases.
Topics: Academic Dissertations as Topic; Adult; Aged; Aldosterone; Diagnosis, Differential; Electrolytes; Ev | 1972 |
A new male pseudo-hermaphroditism associated with hypertension due to a block of 17 -hydroxylation.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aldosterone; Corticosterone; Desoxycorticosterone | 1972 |
New evidences of disturbances of mineralocorticoid activity in benign, uncomplicated essential hypertension.
Topics: 17-Hydroxycorticosteroids; Adult; Aldosterone; Female; Humans; Hypertension; Male; Metabolic Clearan | 1972 |
[Mineralocorticoid reaction of hypertensive patients to spirolactone].
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Metabolic Clearance Rate; Sodium; Spironolactone | 1972 |
[Sympathico-reno-adrenal relationship in some kinds of hypertensions].
Topics: Adrenal Glands; Aldosterone; Catecholamines; Humans; Hypertension; Kidney; Renin; Sympathetic Nervou | 1972 |
Hypertension with primary and secondary hyperaldosteronism.
Topics: Adenoma; Aldosterone; Blood Pressure; Contraceptives, Oral; Diuretics; Humans; Hyperaldosteronism; H | 1972 |
Renin, aldosterone, sodium and hypertension.
Topics: Adrenal Glands; Adult; Age Factors; Aged; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Kid | 1972 |
Electrolyte changes in patients with subarachnoid haemorrhage.
Topics: Acute Disease; Aldosterone; Alkalosis, Respiratory; Aminohippuric Acids; Carbon Dioxide; Extracellul | 1972 |
Studies on the renin-angiotensin-aldosterone system: studies on histological changes in adrenal and renal tissue; a follow-up study of postoperative blood pressure in primary and idiopathic aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Biopsy; Blood P | 1972 |
Steroid secretion by the enucleated rat adrenal: measurements during salt retention and the development of hypertension.
Topics: Adrenal Glands; Adrenal Medulla; Aldosterone; Animals; Blood Pressure; Chromatography, Thin Layer; C | 1972 |
[SP 54 therapy in hypertension. The effect of SP 54 on blood pressure, renin and aldosterone as well as electrolyte balance in patients with hypertension].
Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Midd | 1972 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-1972.
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Diagnosis, Di | 1972 |
Propranolol inhibition of renin secretion. A specific approach to diagnosis and treatment of renin-dependent hypertensive diseases.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Depression, Chemical; Humans; Hypertens | 1972 |
The pattern of plasma renin activity and aldosterone secretion in normal and hypertensive subjects before and after saline infusions.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Blood Pressure; Di | 1971 |
The pattern of electrolyte excretion in normal and hypertensive subjects before and after saline infusions. A simple electrolyte formula for the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Body Weight; Diet; Female; Hum | 1971 |
The diagnostic value of salt depletion and salt loading in screening for secondary hypertension.
Topics: Adrenal Glands; Aldosterone; Hyperaldosteronism; Hypertension; Hypertonic Solutions; Kidney; Natriur | 1971 |
Saline suppression of plasma aldosterone in hypertension.
Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Infusions, Paren | 1971 |
Renin and aldosterone in essential hypertension.
Topics: Aldosterone; Catecholamines; Diet, Sodium-Restricted; Feces; Humans; Hyperaldosteronism; Hypertensio | 1971 |
Sodium and hypertension.
Topics: Aldosterone; Amidines; Aorta; Depression, Chemical; Diuretics; Epinephrine; Heart Atria; Heart Ventr | 1971 |
Adrenal arteriography and venography in primary aldosteronism.
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Angiog | 1971 |
A decreased metabolic clearance rate of aldosterone in benign essential hypertension.
Topics: Adaptation, Physiological; Adolescent; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hyper | 1971 |
Testosterone-induced 18-hydroxylase block: a new form of steroid hypertension in man.
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Corticosterone; Female; Humans; Hydroxylation; Hyperten | 1971 |
Low renin hypertension: a state of inappropriate secretion of aldosterone.
Topics: Aldosterone; Humans; Hypertension; Renin | 1971 |
Evaluation of renal vascular hypertension and primary hyperaldosteronism.
Topics: Aldosterone; Angiography; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Hyperte | 1971 |
Effects of hydrochlorothiazide, furosemide and ethacrynic acid on pinealectomy-induced hypertension in rats.
Topics: Aldosterone; Animals; Blood Pressure; Ethacrynic Acid; Furosemide; Hydrochlorothiazide; Hypertension | 1971 |
Hypertension and low plasma renin activity: presumptive evidence for mineralocorticoid excess.
Topics: Adrenal Glands; Aldosterone; Blood Pressure; Body Weight; Carbon Dioxide; Chlorides; Female; Humans; | 1971 |
[Pharmacological and clinical bases for the use of diuretics in pregnancy].
Topics: Adult; Aldosterone; Blood Pressure; Carbohydrate Metabolism; Diuretics; Edema; Female; Fetus; Hormon | 1971 |
Evaluation of select criteria for the diagnosis of primary aldosteronism in normokalemic hypertension.
Topics: Adult; Aldosterone; Desoxycorticosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Mi | 1971 |
Effects of an aldosterone antagonist, spironolactone, on pinealectomized rats.
Topics: Adrenal Glands; Aldosterone; Animals; Arteries; Blood Pressure; Epinephrine; Hypertension; Male; Min | 1971 |
Sodium, aldosterone and hypertension.
Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Kidney; Kidney Diseases; Sodium | 1971 |
[Primary aldosteronism from the viewpoint of own observations].
Topics: 17-Ketosteroids; Adrenal Glands; Aldosterone; Germany, East; Humans; Hyperaldosteronism; Hypertensio | 1971 |
Fecal and salivary electrolytes in the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Feces; Female; Humans; Hyperaldosteronism; Hyp | 1971 |
[Clinical studies on the relation between aldosterone and various hypertensive and renal diseases. 1. Studies on the secretion and metabolism of aldosterone in various hypertensive and renal diseases].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Kidney Diseases; Time Factors; Tritium | 1971 |
Structure-function studies of the regenerating adrenal.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Corticosterone; Culture Techniques; Desoxycorti | 1969 |
Episodic hypertension associated with positive renin assays after renal transplantation.
Topics: Adult; Aldosterone; Humans; Hypertension; Ischemia; Kidney Transplantation; Male; Renin; Transplanta | 1966 |
Plasma renin activity and aldosterone secretion in a pregnant woman with primary aldosteronism.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Biological Assay; Female; Humans; Hyper | 1967 |
Renal hypertension and renin hypertension in intact and in adrenalectomized rats.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Constriction; Corticosterone; Dexamethasone; Hy | 1969 |
In vitro metabolism of progesterone by the adrenals of spontaneously hypertensive rats.
Topics: Adrenal Glands; Aldosterone; Animals; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Female; | 1969 |
Effects of sodium loading, sodium depletion and posture on plasma aldosterone concentration and renin activity in hypertensive patients.
Topics: Adolescent; Adult; Aged; Aldosterone; Child; Female; Humans; Hydrocortisone; Hypertension; Male; Mid | 1969 |
[Primary aldosteronism without association of hypokalemia].
Topics: 17-Hydroxycorticosteroids; Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hyperkalemia; Hy | 1969 |
Hypertension induced by oral contraceptives containing estrogen and gestagen. Effects on plasma renin activity and aldosterone excretion.
Topics: Adult; Aldosterone; Benzothiadiazines; Blood Pressure; Contraceptives, Oral; Female; Humans; Hyperte | 1969 |
Hypertension and hyperaldosteronism with low plasma renin concentration: analysis of a series of eighty-two patients.
Topics: Adrenal Glands; Aldosterone; Body Weight; Humans; Hyperaldosteronism; Hypertension; Plasma Volume; P | 1969 |
[Saluretics and hypertension].
Topics: Aldosterone; Catecholamines; Diuretics; Humans; Hypertension; Potassium; Sodium | 1969 |
Suppressed plasma renin activity in in hypertensive patients--its evaluation for the diagnosis of primary aldosteronism.
Topics: Aldosterone; Cushing Syndrome; Diet, Sodium-Restricted; Glomerulonephritis; Humans; Hydrochlorothiaz | 1969 |
[Measurement of aldosterone in peripheral blood and urine--analysis of the method and evaluation of estimated values in normal subjects and aldosteronism].
Topics: Adult; Aldosterone; Carbon Isotopes; Child; Chromatography, Paper; Female; Humans; Hyperaldosteronis | 1969 |
[Aldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin | 1969 |
[Aldosterone secretion in arterial hypertension].
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Middle Aged | 1969 |
[Morphological signs of hyperactivity of the renin-aldosterone system in experimental cadmium-induced hypertension].
Topics: Aldosterone; Animals; Cadmium; Hypertension; Juxtaglomerular Apparatus; Rats; Renin | 1969 |
Pseudopheochromocytoma--adrenomedullary response to venography.
Topics: Adrenal Medulla; Aldosterone; Diatrizoate; Epinephrine; Humans; Hydrocortisone; Hypertension; Norepi | 1970 |
A physiologic approach to curable hypertension.
Topics: Adrenal Gland Neoplasms; Aldosterone; Cardiovascular Diseases; Catecholamines; Diagnosis, Differenti | 1970 |
Studies on catecholamines, renin and aldosterone following Catapresan (2-(2,6-dichlor-phenylamine)-2-imidazoline hydrochloride) in hypertensive patients.
Topics: Adolescent; Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Catecholamines; Depre | 1970 |
Renin, aldosterone, and hypertension. The hepatic metabolism of renin and aldosterone. A review with new observations on the hepatic clearance of renin.
Topics: Aldosterone; Animals; Blood; Disease Models, Animal; Dogs; Heart Failure; Hemorrhage; Hepatic Veins; | 1970 |
The intercurrent hypertension of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Body Weight; Chronic Disease; Desoxyc | 1970 |
The role of renin in the exaggerated natriuresis of hypertension.
Topics: Adult; Aldosterone; Ethacrynic Acid; Female; Furosemide; Glomerular Filtration Rate; Humans; Hyperal | 1970 |
[Orthostatic reaction disorders in the etiopathogenesis of various pathologic conditions].
Topics: Addison Disease; Aldosterone; Edema; Hemodynamics; Humans; Hypertension; Hypertension, Renal; Hypote | 1970 |
[Research on arterial hypertension. Significance of aldosterone, catecholamines, amino acids and some electrolytes].
Topics: Aldosterone; Amino Acids; Catecholamines; Electrolytes; Humans; Hypertension; Hypertension, Malignan | 1970 |
Oral contraceptives and hypertension.
Topics: Aldosterone; Animals; Contraceptives, Oral; Hypertension; Progesterone; Rabbits; Sodium Chloride | 1970 |
[Renin-angiotensin-aldosterone system: effect of the hypertensive agents on plasma renin activity and clinical application, especially in screening of primary aldosteronism and other simialr diseases].
Topics: Adolescent; Adult; Aldosterone; Animals; Blood Pressure; Denervation; Diazoxide; Dogs; Female; Glome | 1970 |
The effects of progesterone on the responses of the cardiovascular system to intravenous infusions of aldosterone.
Topics: Aldosterone; Animals; Blood Pressure; Contraceptives, Oral; Drug Synergism; Female; Femoral Artery; | 1970 |
[Functional hyperaldosteronism].
Topics: Aldosterone; Dexamethasone; Hyperaldosteronism; Hypertension; Hypokalemia; Renin | 1970 |
A preliminary evaluation for primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Desoxycorticosterone; Fludrocortisone | 1970 |
Hypertension and severe hyperkalaemia associated with suppression of renin and aldosterone and completely reversed by dietary sodium restriction.
Topics: Aldosterone; Ammonia; Bicarbonates; Blood Urea Nitrogen; Child; Chlorides; Creatinine; Diet, Sodium- | 1970 |
Hypertension and adrenal cortex disease. A review of 100 autopsied cases.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Autopsy; Fem | 1970 |
Plasma renin activity in human hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Contraceptives, Oral; Female; Humans; Hypertension; Kidney Failu | 1970 |
Sodium homeostasis, salt appetite, and hypertension.
Topics: Aldosterone; Animals; Anxiety; Appetite; Bicarbonates; Diet; Diet, Sodium-Restricted; Female; Food A | 1970 |
Sodium balance, plasma renin, and aldosterone in hypertension.
Topics: Aldosterone; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; R | 1970 |
[Research on arterial hypertension. Significance of aldosterone, catecholamines, amino acids and some electrolytes in compensated and decompensated cardiac lesions].
Topics: Adult; Aged; Aldosterone; Amino Acids; Catecholamines; Coronary Disease; Electrolytes; Female; Heart | 1970 |
Panel discussion: the incidence of aldosteronism and early detection in the population.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Immunoassay | 1970 |
[Hypertension and tachycardia in acute intermittent porphyria].
Topics: Adult; Aldosterone; Amino Acids; Anemia; Blood Pressure; Catecholamines; Depression, Chemical; Elect | 1970 |
Hypertension, adrenal abnormalities, and alterations in plasma renin activity.
Topics: Adenoma; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldoste | 1970 |
Plasma renin activity and aldosterone secretion rate in hypertension. The distinction between primary and secondary hyperaldosteronism.
Topics: Adolescent; Adrenalectomy; Adult; Aged; Aldosterone; Carbon Isotopes; Creatinine; Female; Humans; Hy | 1970 |
[Diagnosis of arterial hypertension].
Topics: 17-Hydroxycorticosteroids; Aldosterone; Angiography; Aortic Valve Stenosis; Arteries; Catecholamines | 1970 |
Sodium space and electrolyte excretion during the menstrual cycle.
Topics: Aldosterone; Basal Metabolism; Body Temperature; Body Weight; Creatinine; Female; Humans; Hypertensi | 1971 |
Dietary salt intake in hypertensive patients with normal and low plasma renin activity.
Topics: Adult; Aldosterone; Creatinine; Diet; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Re | 1971 |
Hypertension in apparently normal children.
Topics: Adolescent; Age Factors; Aldosterone; Blood Pressure; Child; Child, Preschool; Female; Humans; Hyper | 1971 |
[Clinical evaluation of a new method for the determination of urinary aldosterone].
Topics: Aldosterone; Chromatography, Thin Layer; Edema; Female; Heart Diseases; Humans; Hyperaldosteronism; | 1971 |
Primary aldosteronism associated with acute intermittent porphyria. Report of a case.
Topics: Acyltransferases; Adult; Aldosterone; Catheterization; Enzyme Induction; Feces; Female; Humans; Hype | 1971 |
[Essential hypertension--an endocrine form of hypertension].
Topics: Aldosterone; Humans; Hypertension; Renin | 1971 |
Saline suppression of plasma aldosterone and plasma renin activity in hypertension.
Topics: Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension; Male; Postur | 1971 |
[Endocrinologic and circulatory findings in a case of primary aldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Female; Hemodynamics; Humans; Hyperaldosteronism; Hyp | 1971 |
A dynamic study of plasma renin activity and aldosterone concentration in normal and hypertensive subjects.
Topics: Adolescent; Adult; Aldosterone; Body Weight; Diuresis; Female; Furosemide; Humans; Hyperaldosteronis | 1971 |
Low-renin essential hypertension--another form of childhood hypertension.
Topics: Aldosterone; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Hypertension; Infant; Infan | 1971 |
[Intracellular electrolyte variations in experimental hypertension].
Topics: Aldosterone; Animals; Aorta; Desoxycorticosterone; Humans; Hyperparathyroidism; Hypertension; Male; | 1967 |
[Present hypertension problems].
Topics: Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Renin | 1967 |
[Study of the juxtaglomerular apparatus in various forms of experimental hypertension].
Topics: Aldosterone; Animals; Arteries; Blood Pressure; Constriction; Hyperplasia; Hypertension; Hypertensio | 1967 |
[Primary aldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi | 1967 |
The role of aldosterone in hypernatremic dehydration in infants.
Topics: Aldosterone; Anuria; Dehydration; Gastroenteritis; Humans; Hypernatremia; Hypertension; Hypokalemia; | 1968 |
Effects of renin on aldosterone secretion in the rat.
Topics: Aldosterone; Animals; Arteries; Blood Pressure; Female; Hypertension; Kidney; Myocardium; Nephrectom | 1968 |
Plasma renin activity and aldosterone secretion in hypertensive patients during high and low sodium intake and administration of diuretic.
Topics: Adult; Aldosterone; Blood Pressure; Child; Chlorothiazide; Cushing Syndrome; Diet; Female; Humans; H | 1968 |
Primary aldosteronism: review of 12 cases and present diagnostic criteria.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi | 1968 |
Primary aldosteronism: experience with current diagnostic criteria and surgical treatment in fourteen patients.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Female; Humans; Hyperaldosteron | 1968 |
Incidence of suppressed renin activity and of normokalemic primary aldosteronism in hypertensive Negro patients.
Topics: Adult; Aldosterone; Black People; Chlorothiazide; Diet, Sodium-Restricted; Female; Humans; Hyperaldo | 1968 |
Plasma renin activity in congenital virilizing adrenal hyperplasia.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfun | 1968 |
Unilateral adrenalectomy for aldosteronomas localized preoperatively by differential adrenal vein catheterization.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Angiography; Ao | 1968 |
Hormonally maintained high blood pressure following adrenalectomy in rats with adrenal-regeneration hypertension and its possible significance in the etiology of that disorder.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Blood Pressure; Body Weight; Corticosterone; Fe | 1968 |
Primary aldosteronism.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor An | 1968 |
Metabolic and hormonal studies in a patient with primary aldosteronism, presenting with acute hypokalaemic paresis induced by chlorothiazide.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Chlorothiazide; Diagnosis, Diff | 1968 |
[Excretion of aldosterone and the mineralocorticoid function of adrenal glands in diffuse glomerulonephritis].
Topics: Adolescent; Adrenal Glands; Adult; Aldosterone; Female; Glomerulonephritis; Humans; Hypertension; Ma | 1968 |
Aldosterone secretion rate in the hypertensive form of congenital adrenal hyperplasia.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Aldosterone; Cortisone; Diet; Disorders of Sex Deve | 1968 |
Surgical treatment of adrenal disorders associated with increased hormone production.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adult; | 1968 |
Aldosteronism in hypertension. The spironolactone response test.
Topics: Adrenalectomy; Aldosterone; Blood Pressure; Body Weight; Diagnosis, Differential; Electrolytes; Huma | 1968 |
Aldosterone secretion in hypertension.
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Antihyp | 1968 |
Incidence of primary aldosteronism uncomplicated "essential" hypertension. A prospective study with elevated aldosterone secretion and suppressed plasma renin activity used as diagnostic criteria.
Topics: Adolescent; Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hyperte | 1968 |
Studies on cardiac output to blood volume, and renal circulation in chronic congestive heart failure.
Topics: Adult; Aged; Aldosterone; Arteriosclerosis; Blood Pressure; Blood Volume; Cardiac Output; Chronic Di | 1968 |
Metabolic studies on hypertensive patients with suppressed plasma renin activity not due to hyperaldosternosm.
Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Blood Volume; Body Weight; E | 1968 |
[Secretion, plasma concentration, distribution, metabolism and excretion of aldosterone in healthy and sick subjects].
Topics: Aldosterone; Edema; Glomerulonephritis; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Liv | 1968 |
[A case of juvenile arterial hypertension associated with hypokalemia and low aldosterone secretion (Liddle syndrome)].
Topics: Adolescent; Aldosterone; Female; Humans; Hypertension; Hypokalemia; Spironolactone; Triamterene | 1968 |
Syndrome of idiopathic hyperkalaemia and hypertension with decreased plasma renin activity: effects on plasma renin and aldosterone of reducing the serum potassium level.
Topics: Adolescent; Aldosterone; Chlorothiazide; Corticosterone; Glomerular Filtration Rate; Humans; Hydroco | 1968 |
[Aldosterone and arterial hypertension].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal | 1968 |
[Excretion of aldosterone in pregnancy hypertension].
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular | 1968 |
[Pathological evaluation of adrenal cortical adenoma with essential hypertension].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Midd | 1968 |
Test for pathologic secretion of aldosterone.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diet; Humans; Hyperaldosteronism; Hyperplasia; Hypert | 1968 |
[Clinical management of arterial hypertension at the Hôtel-Dieu de Montréal].
Topics: Aldosterone; Angiography; Antihypertensive Agents; Diet Therapy; Diuretics; Electrolytes; Histamine; | 1968 |
Aldosterone and hypertension.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia | 1969 |
Intravenously administered chlorothiazide in diagnostic evaluation of hypertensive disease.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Aldosterone; Blood Pre | 1969 |
A concluding response.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin | 1969 |
Correlation of plasma renin activity and aldosterone secretion rate in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension; Hyperten | 1969 |
[The pathogenesis of hypertension and sinus tachycardia in human thallium intoxication].
Topics: Adult; Aldosterone; Antidotes; Blood Pressure; Catecholamines; Heart Rate; Humans; Hypertension; Inj | 1969 |
Deoxycorticosterone production in adrenal regeneration hypertension: in vitro vs. in vivo comparison.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Analysis of Variance; Animals; Blood Pressure; Body Weig | 1969 |
Secretion of sodium and potassium by the parotid gland in essential hypertension.
Topics: Adult; Aldosterone; Chlorides; Female; Humans; Hypertension; Male; Parotid Gland; Potassium; Saliva; | 1969 |
[The importance of primary aldosteronism as cause of "essential" hypertension].
Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Middle Aged; Potassium; | 1969 |
[Hypokalemic metabolic alkalosis].
Topics: Acid-Base Equilibrium; Adrenal Gland Diseases; Adrenocortical Hyperfunction; Adult; Aldosterone; Alk | 1969 |
Salivary sodium-potassium ratio and plasma renin activity in hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Diet, Sodium-Restricted; Female; Humans; Hyper | 1969 |
Non-tumorous "primary" aldosteronism. I. Type relieved by glucocorticoid (glucocorticoid-remediable aldosteronism).
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenalectomy; Adult; Aldosterone; Androgens | 1969 |
Potassium loss with thiazide therapy.
Topics: Aldosterone; Blood Gas Analysis; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Natriuresi | 1969 |
Plasma renin activity in the diagnosis of primary aldosteronism: failure to distinguish primary aldosteronism from essential hypertension.
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Animals; Biological Assay; Blood Urea Nitrogen; Chlorot | 1969 |
Secretion and turnover of aldosterone in various pathological states.
Topics: Adolescent; Adult; Aldosterone; Chronic Disease; Dehydration; Edema; Glomerulonephritis; Heart Failu | 1969 |
[Effect of the biotron on the activity of aldosterone in hypertensive patients. (The sodium-potassium coefficient in the saliva)].
Topics: Aldosterone; Climate; Humans; Hypertension; Potassium; Saliva; Sodium | 1965 |
[Studies on the secretion and metabolic clearance rates and the mean plasma concentration of aldosterone in man].
Topics: Adult; Aged; Aldosterone; Female; Glomerulonephritis; Humans; Hypertension; Injections, Intravenous; | 1965 |
The pharmacology and clinical use of rauwolfia, hydralazine, thiazides, and aldosterone antagonists in arterial hypertension.
Topics: Aldosterone; Benzothiadiazines; Diuretics; Humans; Hydralazine; Hypertension; Phytotherapy; Plants, | 1966 |
Relation between potassium balance and aldosterone secretion in normal subjects and in patients with hypertensive or renal tubular disease.
Topics: Acidosis, Renal Tubular; Adrenal Gland Neoplasms; Adult; Aldosterone; Ethacrynic Acid; Female; Human | 1966 |
[Determination of the plasma renin activity in 261 hypertensives].
Topics: Aldosterone; Female; Humans; Hypertension; Male; Renin; Sodium | 1966 |
The role of catecholamines in the pathogenesis of hypertension.
Topics: Aldosterone; Humans; Hypertension; Norepinephrine; Sodium; Urine | 1966 |
[The importance of aldosterone in the development of edema and hypertension].
Topics: Aldosterone; Edema; Humans; Hypertension | 1966 |