Page last updated: 2024-11-07

aldosterone and Hypertension

aldosterone has been researched along with Hypertension in 5104 studies

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
" Prostasin was measured in plasma and urine from type 2 diabetic patients with resistant hypertension (n = 112) randomized to spironolactone/placebo in a clinical trial."9.24Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin. ( Bistrup, C; Hansen, MR; Hansen, PB; Hinrichs, GR; Jacobsen, IA; Jensen, BL; Kurt, B; Oxlund, C; Schwarzensteiner, I; Stæhr, M; Svenningsen, P; Thuesen, AD; Toft, A, 2017)
"Angiotensin II receptor blockers (ARBs) have been widely used to treat hypertension and large-scale clinical studies have shown various benefits."9.22Changeover Trial of Azilsartan and Olmesartan Comparing Effects on the Renin-Angiotensin-Aldosterone System in Patients with Essential Hypertension after Cardiac Surgery (CHAOS Study). ( Arimoto, M; Hata, H; Osaka, S; Sakino, H; Sezai, A; Shiono, M; Yaoita, H, 2016)
"To address the cardiovascular mechanisms involved in response to an angiotensin II receptor antagonist, losartan, and continuous positive airway pressure (CPAP) as add-on treatment for hypertension and OSA."9.22Neuroendocrine and Inflammatory Responses to Losartan and Continuous Positive Airway Pressure in Patients with Hypertension and Obstructive Sleep Apnea. A Randomized Controlled Trial. ( Lindberg, C; Manhem, K; Peker, Y; Rosengren, A; Thunström, E; Yucel-Lindberg, T, 2016)
"5 mg hydrochorothiazide + 5 mg amlodipine, 86 patients with resistant hypertension were randomized to the add-on 25 mg spironolactone (MRB group, n = 46) or 5 mg ramipril (RASB group, n = 40) groups for 12 weeks."9.19Greater efficacy of aldosterone blockade and diuretic reinforcement vs. dual renin-angiotensin blockade for left ventricular mass regression in patients with resistant hypertension. ( Azizi, M; Bobrie, G; Chatellier, G; Frank, M; Ménard, J; Perdrix, L; Plouin, PF, 2014)
"The purpose of this study was to evaluate the effects of spironolactone on dialysis patients with refractory hypertension and possible adverse effects."9.19Effects of spironolactone on dialysis patients with refractory hypertension: a randomized controlled study. ( Chen, J; Ni, X; Wu, F; Xia, M; Ying, G; Zhang, J; Zhang, P, 2014)
"The aim was to compare the antiproteinuric effect of aliskiren and ramipril in hypertensive patients with type 2 diabetes and microalbuminuria."9.17Time course of antiproteinuric effect of aliskiren in arterial hypertension associated with type 2 diabetes and microalbuminuria. ( Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Perrone, T; Preti, P; Zoppi, A, 2013)
"The primary objective of this study was to evaluate the antihypertensive effect of low dose spironolactone added to triple therapy for resistant hypertension in patients with type 2 diabetes measured by ambulatory monitoring."9.17Low dose spironolactone reduces blood pressure in patients with resistant hypertension and type 2 diabetes mellitus: a double blind randomized clinical trial. ( Gram, J; Henriksen, JE; Jacobsen, IA; Oxlund, CS; Schousboe, K; Tarnow, L, 2013)
" We conducted an open-label, randomized trial to compare the effects of cilnidipine against those of amlodipine on blood pressure (BP), albuminuria, and plasma aldosterone concentration in hypertensive patients with mild- to moderate-stage chronic kidney disease."9.17L/N-type calcium channel blocker cilnidipine reduces plasma aldosterone, albuminuria, and urinary liver-type fatty acid binding protein in patients with chronic kidney disease. ( Abe, M; Inoshita, A; Maruyama, N; Okada, K; Soma, M; Suzuki, H; Yoshida, Y, 2013)
" We wanted to test the hypotheses that amiloride and spironolactone induced potassium retention reduces ambulatory blood pressure (ABP) and central blood pressure (CBP) during baseline conditions and after furosemide and that the tubular transport via the epithelial sodium channels (ENaCs) and aquaporin-2 (AQP2) water channels was increased by furosemide in arterial hypertension."9.17Effect of amiloride and spironolactone on renal tubular function and central blood pressure in patients with arterial hypertension during baseline conditions and after furosemide: a double-blinded, randomized, placebo-controlled crossover trial. ( Jensen, JM; Larsen, T; Lauridsen, TG; Matthesen, SK; Pedersen, EB; Vase, H, 2013)
" In this study, we conducted an open-label and randomized trial to compare the effects of benidipine with those of amlodipine on blood pressure (BP), albuminuria and aldosterone concentration in hypertensive patients with mild-to-moderate stage chronic kidney disease (CKD)."9.15Benidipine reduces albuminuria and plasma aldosterone in mild-to-moderate stage chronic kidney disease with albuminuria. ( Abe, M; Fujita, T; Maruyama, N; Maruyama, T; Matsumoto, K; Matsumoto, S; Okada, K; Soma, M, 2011)
"The Ouabain and Adducin for Specific Intervention on Sodium in Hypertension (OASIS-HT) Trial was a phase-2 dose-finding study of rostafuroxin, a digitoxygenin derivative, which selectively antagonizes the effects of endogenous ouabain (EO) on Na+,K+-ATPase and mutated adducin."9.15Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin. ( Bacchieri, A; Barton, J; Bianchi, G; Citterio, L; de Leeuw, PW; Dłużniewski, M; Espositi, ED; Ferrari, P; Glorioso, N; Januszewicz, A; Kawecka-Jaszcz, K; Lanzani, C; Manunta, P; Milyagin, V; Nikitin, Y; Souček, M; Staessen, JA; Stolarz-Skrzypek, K; Thijs, L; Timio, M; Tykarski, A; Valentini, G, 2011)
"The Aliskiren in Left Ventricular Hypertrophy (ALLAY) trial randomised 465 hypertensive overweight subjects with LVH to the direct renin inhibitor aliskiren 300 mg, losartan 100 mg or the combination and followed patients for 9 months."9.15Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertension. ( Appelbaum, E; Dahlöf, B; Desai, A; Lukashevich, V; Pouleur, AC; Prescott, MF; Smith, BA; Solomon, SD; Uno, H, 2011)
"Participants enrolled in this trial were outpatients with essential hypertension after cardiac surgery who had received candesartan for more than one year."9.15Effects of olmesartan on the renin-angiotensin-aldosterone system for patients with essential hypertension after cardiac surgery--investigation using a candesartan change-over study. ( Hata, M; Sezai, A; Shiono, M; Soma, M; Unosawa, S; Wakui, S; Yoshitake, I, 2011)
" Spironolactone is thought to be an important addition to resistant hypertension (RH) treatment."9.14Aldosterone excess or escape: Treating resistant hypertension. ( Adriana de Souza, L; Coca, A; Coelho, OR; Ferreira-Melo, S; Martins, LC; Moreno, H; Pimenta, E; Sierra, C; Ubaid-Girioli, S; Yugar-Toledo, JC, 2009)
"Forty type 2 diabetic patients with hypertension and nephropathy receiving angiotensin receptor II blockers were enrolled and randomly divided into two groups: the efonidipine group was administered efonidipine hydrochloride ethanolate 40 mg/day and the amlodipine group was admin-istered amlodipine besilate 5 mg/day for 12 months."9.14Protective effects of efonidipine, a T- and L-type calcium channel blocker, on renal function and arterial stiffness in type 2 diabetic patients with hypertension and nephropathy. ( Ban, N; Endo, K; Kawana, H; Miyashita, Y; Nagayama, D; Ohhira, M; Oyama, T; Saiki, A; Sasaki, H; Shirai, K; Yamaguchi, T, 2009)
"This study was conducted to determine the effects of a tablet combining losartan/hydrochlorothiazide (L/HCTZ) in comparison with losartan alone in Japanese diabetic patients with hypertension."9.14Safety and benefits of a tablet combining losartan and hydrochlorothiazide in Japanese diabetic patients with hypertension. ( Ichihara, A; Itoh, H; Kinouchi, K; Kurauchi-Mito, A; Sakoda, M, 2009)
"A total of 50 stable outpatients with essential hypertension who had received candesartan for more than 1 year were randomized into two groups: control group (n=25): continuous candesartan treatment at a stable dose; and olmesartan group (n=25): candesartan (8 mg day(-1)) was changed to olmesartan given at a dose of 20 mg day(-1)."9.14Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension. ( Fujii, M; Horie, M; Kawahara, C; Nishiyama, K; Tsutamoto, T; Yamaji, M; Yamamoto, T, 2010)
"A common pharmacologic test for the diagnosis of primary aldosteronism (PA) is the administration of captopril to determine whether an abnormal plasma aldosterone concentration (PAC) to plasma renin activity (PRA) ratio(ARR) persists, although active renin concentration (ARC) may offer advantages with regard to processing and standardization."9.14Diagnosis of primary aldosteronism: comparison of post-captopril active renin concentration and plasma renin activity. ( Chang, CC; Chang, HW; Chueh, SC; Fang, CC; Ho, YL; Huang, KH; Kuo, CC; Lin, CY; Lin, LY; Lin, SL; Lin, YH; Liu, KL; Tsai, CT; Wang, SM; Wu, KD; Wu, VC; Yen, RF, 2010)
"The aim of the study was evaluation of spironolactone effect on concentration of endothelin-1 (ET-1 - vasoconstrictive substance produced by endothelial cells) and aldosterone (Ald) and plasma renin activity (PRA) in patients with primary arterial hypertension (AH): group A--smoking patients (11 individuals) in comparison with group B--non-smoking ones (12 individuals)."9.14[Does spironolactone use at arterial hypertension therapy protect endothelium also in smoking patients?]. ( Kara-Perz, H; Kosicka, T; Perz, S, 2009)
" We investigated the hypothesis that simvastatin decreased muscle sympathetic nerve activity (MSNA) in 31 hypertensive subjects with hypercholesterolemia (aged 38."9.14Simvastatin reduces sympathetic activity in men with hypertension and hypercholesterolemia. ( Abramczyk, P; Bidiuk, J; Ciarka, A; Dobosiewicz, A; Gaciong, Z; Lewandowski, J; Siński, M, 2010)
"In this study we evaluated the effect of a dual blockade with enalapril and losartan on the reduction of overt macroproteinuria and its potential mechanism(s) in hypertensive patients with type 2 diabetes."9.12Dual blockade of angiotensin II with enalapril and losartan reduces proteinuria in hypertensive patients with type 2 diabetes. ( Hirata, A; Igarashi, M; Kadomoto, Y; Tominaga, M, 2006)
"The patients with essential hypertension were randomly divided into 2 groups; 1 group was treated with an ARB, candesartan (8 mg/day), for 1 year (ARB group) and other group was treated with the ARB for the first 6 months and with the ARB plus SPRL (25 mg/day) for the next 6 months (combination group)."9.12Effects of spironolactone during an angiotensin II receptor blocker treatment on the left ventricular mass reduction in hypertensive patients with concentric left ventricular hypertrophy. ( Date, T; Kawai, M; Mochizuki, S; Seki, S; Shimizu, M; Taniguchi, I; Taniguchi, M; Yoshida, S, 2006)
" It is not known if subjects with a high ratio have aldosteronism or aldosterone-sensitive hypertension is debated but it is important to know whether spironolactone is superior to other diuretics such as bendroflumethiazide in this setting."9.12Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study. ( Alhashmi, K; Connell, JM; Ford, I; MacDonald, TM; McInnes, GT; McMahon, AD; Parthasarathy, HK; Struthers, AD, 2007)
"One hundred eighteen patients with mild-to-moderate essential arterial hypertension were randomized to treatment with 10 mg/d of amlodipine (group 1), 20 mg/d of quinapril (group 2), or 2 x 50 mg/d of losartan (group 3)."9.10Effect of amlodipine, quinapril, and losartan on pulse wave velocity and plasma collagen markers in patients with mild-to-moderate arterial hypertension. ( Kawecka-Jaszcz, K; Klocek, M; Rajzer, M, 2003)
"Eplerenone is a highly selective aldosterone blocking agent, which was recently approved for the treatment of hypertension and has also been shown to reduce mortality in post-myocardial infarction patients with heart failure."9.10Assessment of the novel selective aldosterone blocker eplerenone using ambulatory and clinical blood pressure in patients with systemic hypertension. ( Carr, AA; Jordan, R; Krause, S; Oigman, W; Roniker, B; White, WB, 2003)
"Previous reports have demonstrated the antihypertensive efficacy of high doses of spironolactone in subjects with primary aldosteronism and, to a lesser degree, subjects with resistant hypertension."9.10Efficacy of low-dose spironolactone in subjects with resistant hypertension. ( Calhoun, DA; Nishizaka, MK; Zaman, MA, 2003)
"Patients with mild-to-moderate primary hypertension and left ventricular hypertrophy were randomized in a double-blind study to receive treatment with either the angiotensin II type 1 (AT1) receptor antagonist irbesartan (n = 43), or the beta1-adrenergic receptor blocker atenolol (n = 43)."9.10Aldosterone synthase (CYP11B2) -344 C/T polymorphism is related to antihypertensive response: result from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial. ( Hägg, A; Kahan, T; Karlsson, J; Kurland, L; Lind, L; Malmqvist, K; Melhus, H; Nyström, F; Ohman, P, 2002)
" In the present study, we examined the effect on left ventricular hypertrophy of adding a low dose of the mineralocorticoid receptor antagonist spironolactone (25 mg/d) to an angiotensin-converting enzyme inhibitor (enalapril maleate) in patients with essential hypertension."9.09Effects of spironolactone and angiotensin-converting enzyme inhibitor on left ventricular hypertrophy in patients with essential hypertension. ( Saruta, T; Sato, A; Suzuki, Y, 1999)
"To determine the relationship between endothelin-1 (ET-1), human atrial natriuretic peptide (hANP), plasma-renin activity (PRA) and 24-h urinary excretion of aldosterone (U-Ald) in pregnancy-induced hypertension (PIH)."9.09Plasma human atrial natriuretic peptide, endothelin-1, aldosterone and plasma-renin activity in pregnancy-induced hypertension. ( Bogdanovska, SV; Gerasimovska, BD; Lozance, LA; Maleska, VT; Masin-Paneva, J; Zafirovska, KG, 1999)
"Since renal sympathetic nerves are involved in the regulation of sodium excretion, we investigated whether treatment with urapidil, an alpha1-adrenoceptor blocking agent which also lowers sympathetic activity, alters sodium excretory capacity in patients with essential hypertension."9.09Renal haemodynamics and sodium excretory capacity during urapidil treatment in patients with essential hypertension. ( de Leeuw, PW; Fuss-Lejeune, M; Kroon, AA; Lavrijssen, AT; Schiffers, PM, 2000)
"This multicenter study evaluated the efficacy of candesartan cilexetil, an angiotensin II type 1 receptor antagonist, used alone or in combination with amlodipine or in combination with amlodipine and hydrochlorothiazide in the treatment of patients with moderate-to-severe essential hypertension."9.09Efficacy of candesartan cilexetil alone or in combination with amlodipine and hydrochlorothiazide in moderate-to-severe hypertension. UK and Israel Candesartan Investigators. ( Antonios, TF; He, FJ; MacGregor, GA; Viskoper, JR, 2000)
"We examined the effects of the vasodilator peptide adrenomedullin (AM) infused intravenously into subjects with essential hypertension."9.09Hemodynamic, hormone, and urinary effects of adrenomedullin infusion in essential hypertension. ( Lewis, LK; Nicholls, MG; Richards, AM; Troughton, RW; Yandle, TG, 2000)
"The aim of this study was to investigate the effect of short-term treatment with losartan, a selective and competitive angiotensin II (AngII) receptor blocker, on vascular endothelial growth factor (VEGF), active renin and kallikrein activity (KA) in patients with essential hypertension and primary aldosteronism."9.09Effect of short-term losartan treatment in patients with primary aldosteronism and essential hypertension. ( Atanassova, I; Natchev, E; Orbetzova, M; Tzingilev, D; Zacharieva, S, 2001)
"To examine the factors that determine the blood pressure response to enalapril and nifedipine monotherapy in the treatment of hypertension associated with non-insulin-dependent diabetes mellitus (NIDDM)."9.08Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM. ( Chan, JC; Cheung, CK; Cockram, CS; Law, LK; Nicholls, MG; Swaminathan, R, 1995)
"The effect of calcium channel blocker (CCB), amlodipine (5-10 mg/day) and angiotensin-converting enzyme (ACE) inhibitor, quinapril (10-40 mg/day) on ambulatory blood pressure (ABP), rheological and platelet function in hypertension were compared in this randomised double-blind placebo-controlled cross-over study."9.08Comparison of amlodipine and quinapril on ambulatory blood pressure and platelet function in hypertension. ( Chang, SM; Chou, TC; Ding, YA, 1995)
"In forty six hypertensive patients in whom a high level of clinical suspicion for renovascular hypertension was present on the basis of clinical clues, a captopril test was performed with either 25 mg of captopril or placebo on 2 separate days to determine prospectively the value of the captopril test."9.08'Captopril test', with blood pressure and peripheral renin as response variables in hypertensive patients with suspected renal artery stenosis. ( de Leeuw, PW; Lavrijssen, AT; Schiffers, PM; Schreij, G; van Es, PN, 1995)
"The effects of inhibition of the renin-angiotensin system with quinapril on adrenergic transmission were determined in 18 patients with moderate essential hypertension."9.08Quinapril ACE-inhibition effects on adrenergic parameters in moderate essential hypertension. ( Bronsoms Artero, J; Matas Serra, M; Matè Benito, G; Mauri Nicolas, JM; Torguet Escuder, P; Vallès Prats, M, 1996)
"The effects of two types of angiotensin converting enzyme (ACE) inhibitors, enalapril (long-acting) and captopril (short-acting), on serum electrolytes and circadian rhythm of urinary electrolyte excretions were compared in relation to aldosterone status in patients with essential hypertension and normal renal function."9.07Crossover comparison of the effects of enalapril and captopril on potassium homeostasis in patients with mild hypertension. ( Abe, I; Fujishima, M; Kobayashi, K; Ohmori, S; Ohya, Y; Takata, Y; Tominaga, M; Ueno, M, 1994)
"The present study was performed to clarify changes in plasma levels of 19-hydroxyandrostenedione (19-OH-AD), an amplifier of aldosterone and a possible hypertensinogenic steroid, during several tests for the renin-angiotensin system in 20 patients with aldosterone-producing adenoma (APA) and to determine whether 19-OH-AD participates in the etiology of the hypertension in this disorder."9.07Low plasma 19-hydroxyandrostenedione levels in patients with aldosterone-producing adenoma. ( Miura, K; Miyazaki, S; Morita, H; Mune, T; Yamakita, N; Yasuda, K, 1993)
"The authors assessed in 20 subjects with mild or medium severe arterial hypertension basal and stimulated values of plasma renin activity (PRA) and aldosterone before onset of treatment and after 6-week therapy with enalapril (ENAP KRKA) or metoprolol (Vasocardin Slovakofarma)."9.07[The importance of studying the renin-angiotensin-aldosterone system in essential arterial hypertension in clinical practice. Activity of the renin-angiotensin-aldosterone system during treatment of hypertension with ACE-inhibitors and beta blockers]. ( Chamulová, M; Hrnciar, J; Hrnciarová, M; Kreze, A; Lepej, J; Okálová, D, 1994)
"Ketanserin, a serotonin-2-receptor antagonist, was administered to 16 patients with mild to moderate essential hypertension in randomized single-blind placebo controlled study."9.07[Influence of chronic ketanserin therapy on blood pressure and certain humoral and metabolic factors in patients with mild to moderate primary essential hypertension]. ( Berent, H; Brym, E; Czerniewska, E; Januszewicz, W; Knypl, K; Kuçzyńska, K; Wacławek-Maczkowska, J; Wasowska, T; Wocial, B, 1993)
" After a two-week, placebo run-in phase, 110 patients with mild to moderate hypertension were randomised to receive 10 mg lisinopril or enalapril, or placebo for 4 weeks."9.07Twenty-four hour blood pressure effect of once-daily lisinopril, enalapril, and placebo in patients with mild to moderate hypertension. ( Dunne, B; Glazer, N; Kostis, JB; Miller, WE; Rector, DJ; Tresznewsky, ON; Whelton, A, 1992)
"The effects of a sustained-release formulation of the calcium antagonist nicardipine on left ventricular (LV) mass, Doppler transmitral velocity profiles and plasma neurohumoral studies were analyzed in patients with mild to moderate systemic hypertension."9.07Effects of sustained-release nicardipine on regression of left ventricular hypertrophy in systemic hypertension. ( Adler, J; Dittrich, HC; Ong, J; Reitman, M; Weber, M; Ziegler, M, 1992)
"The short-term effects of atenolol and nifedipine on plasma levels of atrial natriuretic peptide (ANP), plasma renin activity (PRA), and plasma aldosterone (PA) were studied in two groups of patients with uncomplicated essential hypertension."9.07Short-term effects of atenolol and nifedipine on atrial natriuretic peptide, plasma renin activity, and plasma aldosterone in patients with essential hypertension. ( Bucci, V; Casale, R; Colantonio, D; Desiati, P; Giandomenico, G; Pasqualetti, P, 1991)
"Nifedipine causes an acute and a sustained reduction in sodium balance in patients with essential hypertension."9.07Acute and sustained changes in sodium balance during nifedipine treatment in essential hypertension. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR, 1991)
"The effects of 6 weeks of treatment with dilevalol 100 mg once daily, or carteolol 10 mg once daily, on renal blood flow (RBF), glomerular filtration rate (GFR) and total renal vascular resistance (TRR) were studied in 10 patients with mild-to-moderate essential hypertension in a randomised cross-over experiment."9.06Comparison of the renal effects of dilevalol and carteolol in patients with mild to moderate essential hypertension. ( Baba, T; Murabayashi, S; Takebe, K; Tomiyama, T, 1990)
"The renal, metabolic and antihypertensive effects of enalapril (E) and slow-release verapamil (V) were compared in a 2-month double-blind crossover trial in 22 patients with newly discovered essential hypertension."9.06Antihypertensive and renal effects of enalapril and slow-release verapamil in essential hypertension. A double-blind, randomized study. ( Fagher, B; Henningsen, N; Hulthén, L; Katzman, P; Thulin, T, 1990)
"The purpose of the study was to evaluate the effects of a dihydropyridine calcium antagonist, nicardipine (N), on blood pressure (BP) and aldosterone secretion in hypertensive patients (pt) with primary aldosteronism."9.06[Effect of a calcium inhibitor, nicardipine, on aldosterone secretion in primary hyperaldosteronism]. ( Begasse, F; Chamontin, B; David, D; Salvador, M, 1989)
" To investigate the contribution of sedation to the cardiovascular effects induced by clonidine, we studied patients with essential hypertension on two separate occasions when similar levels of sedation were induced by clonidine and nitrazepam."9.06The haemodynamic and hormonal responses after clonidine occur independently of sedation in essential hypertension. ( Kooner, JS; Mathias, CJ; Peart, WS, 1989)
"This double-blind placebo controlled study investigated the antihypertensive and humoral effects of nifedipine capsules in patients with essential hypertension inadequately controlled (seated diastolic blood pressure greater than or equal to 95 mm Hg) by hydrochlorothiazide (HCTZ) alone."9.06Antihypertensive and humoral effects of nifedipine in essential hypertension uncontrolled by hydrochlorothiazide alone. ( Abraham, PA; Halstenson, CE; Opsahl, JA, 1989)
"The effects of enalapril alone and in combination with the cyclooxygenase inhibitors sulindac and indomethacin on blood pressure (BP), plasma aldosterone, renin activity and converting enzyme activity were evaluated in 29 patients with mild to moderate essential hypertension, 26 of whom had low plasma renin activity."9.06Antihypertensive effect of enalapril in essential hypertension: role of prostacyclin. ( Hammett, DK; Horton, R; Irvin, J; Oparil, S; Wilkins, LH, 1987)
"A series of studies were undertaken to assess the effect of oral fenoldopam, a specific DA1 dopamine receptor agonist on blood pressure and renal function in patients with mild essential hypertension."9.06Studies with fenoldopam, a dopamine receptor DA1 agonist, in essential hypertension. ( Brown, J; Harvey, JN; Lee, MR; Worth, DP, 1986)
"The effects of the addition of a calcium entry antagonist, nifedipine (20-mg tablet twice a day), to an angiotensin converting enzyme inhibitor, captopril (25 mg three times a day), and the addition of captopril to nifedipine were observed in two separate studies in patients with essential hypertension."9.06Captopril and nifedipine in combination for moderate to severe essential hypertension. ( MacGregor, GA; Markandu, ND; Shore, AC; Singer, DR, 1987)
" In nine patients with essential hypertension, following single and multiple doses of ketanserin, assessments were made of blood pressure and heart rate, QT interval, and pressor responses to phenylephrine and angiotensin II."9.06Acute and chronic ketanserin in essential hypertension: antihypertensive mechanisms and pharmacokinetics. ( Donnelly, R; Elliott, HL; Meredith, PA; Reid, JL, 1987)
"The efficacy and tolerability of the new ACE-inhibitor enalapril (MK 421) and the beta 1-selective adrenoceptor blocker atenolol for the treatment of primary hypertension were compared in a double blind parallel study."9.05Enalapril and atenolol in primary hypertension--a comparative study of blood pressure lowering and hormonal effects. ( Karlberg, BE; Ohman, KP, 1984)
"The hormonal and hypotensive effects of a single oral 10 mg dose of enalapril (MK-421), were assessed by a double-blind randomized trial in 12 subjects with essential hypertension, during a 100 and 40 mmol/day sodium intake."9.05Effect of dietary sodium on angiotensin-converting enzyme (ACE) inhibition and the acute hypotensive effect of enalapril (MK-421) in essential hypertension. ( Cubela, R; Jackson, B; Johnston, CI, 1984)
" In 14 patients with mild to moderate essential hypertension, the effects of bucindolol, hydrochlorothiazide and their combination on blood pressure (BP), heart rate (HR) and parameters of the renin-aldosterone system were compared with those after placebo."9.05Bucindolol, a beta-adrenoceptor blocker with vasodilatory action: its effect in systemic hypertension. ( Fedder, IL; Ferguson, RK; Rocci, ML; Rotmensch, HH; Soyka, L; Swanson, BN; Vlasses, PH, 1984)
"The aim of this study was to investigate and compare the effects of two calcium antagonist drugs, verapamil (VER) and nifedipine (NIF), on blood pressure (BP), heart rate (HR), plasma catecholamines (pCA), renin (PRA), plasma aldosterone (pALD), and plasma volume (PV) in a group of patients with mild to moderate essential hypertension."9.05Antihypertensive and humoral effects of verapamil and nifedipine in essential hypertension. ( Agabiti-Rosei, E; Alicandri, CL; Beschi, M; Castellano, M; Corea, L; Fariello, R; Muiesan, G; Romanelli, G, 1982)
"The effect of low doses (25 mg three times a day) of captopril was evaluated in 16 patients with mild to moderate essential hypertension, previously uncontrolled by hydrochlorothiazide."9.05Low-dose captopril: its use in mild to moderate hypertension unresponsive to diuretic treatment. ( Ferguson, RK; Mojaverian, P; Rotmensch, HH; Swanson, BN; Vlasses, PH, 1982)
"Eight patients with essential hypertension completed a double-blind, randomly allocated crossover comparison of either 5 or 10 mg enalapril maleate, 50 mg hydrochlorothiazide, or their combination administered once daily during sequential two-week periods."9.05A comparative pilot study of enalapril, a new converting enzyme inhibitor, and hydrochlorothiazide in essential hypertension. ( Ferguson, RK; Irvin, JD; Lee, RB; Swanson, BN; Vlasses, PH, 1982)
"The effects of captopril and propranolol on blood pressure, heart rate and plasma noradrenaline, renin and aldosterone, and on the responses to changes in posture and to isometric exercise were measured in patients with essential hypertension."9.05The effect of captopril and propranolol on the responses to posture and isometric exercise in patients with essential hypertension. ( Goodwin, FJ; Holly, JM; Marsh, FP; Sharman, VL; Vandenburg, MJ, 1983)
"57 years), with primary arterial hypertension, was submitted to two periods of treatment in a cross-over study with spironolactone and potassium canrenoate."9.05[Clinical study of the efficacy of oral potassium canrenoate and spironolactone in essential arterial hypertension]. ( Fanti, P; Mantellini, R; Sciarra, F; Tosti-Croce, C, 1983)
"The effects on blood pressure, the renin-angiotensin-aldosterone and the kallikrein-kinin systems were investigated in 32 patients with primary hypertension WHO stage I-II treated with captopril."9.05Captopril, aldosterone and urinary kallikrein in primary hypertension. ( Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S, 1983)
"The metabolic effects of piretanide (2 x 6 mg daily) were compared with those of hydrochlorothiazide, in doses of 2 x 25 mg or 2 x 50 mg daily, in a double-blind study consisting of three parallel groups totalling 15 patients with uncomplicated essential hypertension."9.05The effects of piretanide on catecholamine metabolism, plasma renin activity and serum aldosterone: a double-blind pilot comparison against hydrochlorothiazide in patients with essential hypertension. ( Bückert, C; Kirsten, R; Verho, M, 1984)
"Thirty-two patients with moderate to severe essential hypertension whose supine diastolic blood pressure (SDBP) was greater than or equal to 95 mm Hg following 2 weeks' treatment with the optimal dosage of beta blocker-diuretic combination were randomly assigned to the addition of either captopril 25 mg or 50 mg b."9.05Efficacy of low-dose captopril given twice daily to patients with essential hypertension uncontrolled by a beta blocker plus thiazide diuretic. ( Agabiti-Rosei, E; Alicandri, C; Boni, E; Cinquegrana, A; Fariello, R; Montini, E; Muiesan, G; Muiesan, ML; Zaninelli, A, 1984)
"Thirty-two patients with primary hypertension were studied in a double-blind cross-over comparison between the cardioselective beta 1-blocking agent atenolol and the combined alpha- and beta-blocking agent labetalol."9.05Antihypertensive and metabolic effects of increasing doses of atenolol and labetalol. A comparative study in primary hypertension. ( Henningsen, NC; Karlberg, BE; Nilsson, OR; Thulin, T, 1982)
"Twenty-four patients with moderate to severe hypertension were treated for four weeks with captopril, an oral inhibitor of angiotensin-converting enzyme."9.05Captopril in essential hypertension; contrasting effects of adding hydrochlorothiazide or propranolol. ( Banks, RA; Bayliss, J; Jones, JC; MacGregor, GA; Markandu, ND; Roulston, JE, 1982)
"The effects of amiloride hydrochloride on thiazide-induced hypokalemia were evaluated."9.05Response of thiazide-induced hypokalemia to amiloride. ( Chan, L; Maronde, RF; Milgrom, M; Vlachakis, ND, 1983)
"The magnitude and duration of the antihypertensive effect of nifedipine were studied in 7 cases of moderate essential hypertension."9.05Antihypertensive effect of fractionated sublingual administration of nifedipine in moderate essential hypertension. ( Bonnet, F; Corvol, P; Thibonnier, M, 1980)
"Captopril (SQ 14 225), an orally active inhibitor of angiotensin converting enzyme, was evaluated in the treatment of primary (essential) hypertension in a placebo-controlled long-term study."9.05Captopril, an orally active converting enzyme inhibitor, in the treatment of primary hypertension. A controlled long-term study with reference to initial plasma renin activity. ( Asplund, J; Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S, 1981)
"In a single-dose crossover study Captopril (SQ 14225), 1 mg/kg body weight, and Nifedipine (Bay a 1040) 20 mg were administered orally to 12 hospitalized patients with essential hypertension (Stage 1 or 2, W."9.05Antihypertensive and hormonal effects of single oral doses of captopril and nifedipine in essential hypertension. ( Corvol, P; Menard, J; Milliez, P; Sire, O; Soto, ME; Thibonnier, M, 1981)
"Thirty patients with mild or moderate essential hypertension, and a fixed elevation of diastolic blood pressure, were randomly allocated to three groups and treated with propranolol 40 mg x 4 (Group 1), 80 mg x 4 (group 2) and 160 mg x 4 (Group 3)."9.05Correlation between propranolol in plasma and urine, renin-aldosterone system and blood pressure in essential hypertension. ( Andreasen, F; Bjerregaard, P; Kornerup, HJ; Pedersen, EB; Pedersen, OL, 1981)
"In a double-blind crossover study, the antihypertensive effect of hydrochlorothiazide alone and in combination with the beta blocker acebutolol was assessed in 18 patients suffering from mild to moderate hypertension."9.05Merits of adding a beta blocker (acebutolol) to a diuretic (hydrochlorothiazide) in the treatment of hypertension. ( Belleau, LJ; Brossard, JJ; Lebel, M, 1982)
" Since ketanserin, a more specific 5-HT2-serotoninergic (5-HT2) antagonist, has been shown to affect aldosterone secretion in essential hypertension, we have further investigated this mechanism by injecting ketanserin (10 mg i."9.05Effect of ketanserin in primary aldosteronism. ( Armanini, D; Boscaro, M; D'Agostino, D; Mantero, F; Opocher, G; Rocco, S, 1985)
"Renal plasma flow, glomerular filtration rate plasma angiotensin II, aldosterone and arginine vasopressin, free water clearance, blood pressure and body weight in 11 patients with mild to moderate hypertension were determined at the end of consecutive 6 week periods of administration of placebo and verapamil up to 120 mg t."9.05Effect of verapamil on renal plasma flow, glomerular filtration rate and plasma angiotensin II, aldosterone and arginine vasopressin in essential hypertension. ( Danielsen, H; Pedersen, EB; Sørensen, SS; Thomsen, OO, 1985)
"Effect of long-term administration of propranolol was studied in 90 unselected patients with essential hypertension."9.04[Treatment of essential hypertension with propranolol (author's transl)]. ( Braun, B; Klaus, D; Klumpp, F; Lemke, R; Zehner, J, 1976)
" Captopril was shown to be as effective as hydrochlorothiazide in lowering the blood pressure in patients with moderately severe essential hypertension."9.04Hormonal changes with long-term converting-enzyme inhibition by captopril in essential hypertension. ( Johnston, CI; Matthews, PG; McGrath, BP, 1979)
"Eighteen patients with diastolic hypertension (100 to 120 mm Hg), in addition to propranolol, 160 mg daily, and hydrochlorothiazide, 100 mg daily, received progressively increased doses of either minoxidil or placebo in a double-blind crossover study."9.04Effect of minoxidil on blood pressure and hemodynamics in severe hypertension. ( Bryan, RK; Hoobler, SW; Purdy, JM; Rosenzweig, J; Weller, JM, 1977)
"A double-blind study of hydrochlorothiazide and spironolactone, alone and in combination, was conducted in 49 patients with mild-to-moderate essential hypertension after a 4-wk placebo washout period."9.04Hydrochlorothiazide and spironolactone in hypertension. ( Schrijver, G; Weinberger, MH, 1979)
" Plasma renin activity (PRA), the daily urinary excretion of aldosterone (dU-Aldo) and electrolytes were studied before and during dihydralazine therapy (25 mg 3 times daily)."9.04The renin-aldosterone system in dihydralazine therapy during hypertensive pregnancy. ( Lammintausta, R, 1978)
"The antihypertensive effect of the selective beta-1-adrenoceptor blocker, metoprolol, administered once daily was evaluated in 32 patients with primary hypertension."9.04Once-daily metoprolol in primary hypertension. ( Karlberg, BE; Nilsson, O; Nitelius, E; Tolagen, K; Waern, U, 1979)
"15 patients who had benign, uncomplicated essential hypertension, were treated with chlorthiazide (500 mg twice a day) with or without propranolol (10--20 mg 4 times a day), and the effect of the treatment on plasma renin activity (PRA), urinary aldosterone excretion, total body potassium (TBK) and plasma sodium and potassium was evaluated."9.04The renin-aldosterone system and thiazide-induced depletion of total body potassium in essential hypertension. ( Carroll, HJ; Oh, MS, 1978)
" Serial measurements of plasma renin activity (PRA), plasma aldosterone concentration (PA) and blood pressure were performed overnight in patients with borderline (group 1) and sustained essential hypertension (group 2) before and after acute and chronic administration of either propranolol or pindolol."9.04Differential effects of acute and chronic beta-adrenoreceptor blockade on blood pressure and the renin-angiotensin-aldosterone system in essential hypertension. ( Gramann, W; Kolloch, R; Krück, F; Stumpe, KO; Vetter, H, 1976)
"To review comparative efficacy and tolerability data between the two main mineralocorticoid receptor antagonists (MRAs), spironolactone and eplerenone, in patients with resistant hypertension (HTN)."9.01Eplerenone Versus Spironolactone in Resistant Hypertension: an Efficacy and/or Cost or Just a Men's Issue? ( Manolis, AA; Manolis, AS; Manolis, TA; Melita, H, 2019)
" Angiotensin II and aldosterone often collaborate in pathological situations to induce hypertrophy of cardiomyocytes, vascular inflammation, perivascular and interstitial fibrosis, and microvascular rarefaction."8.89Aldosterone mediates cardiac fibrosis in the setting of hypertension. ( Azibani, F; Chatziantoniou, C; Delcayre, C; Fazal, L; Samuel, JL, 2013)
"(2) In RALES, low-dose spironolactone in addition to standard of care, produced a 30% improvement in survival in progressive heart failure, commonly assumed to reflect deleterious effects of aldosterone, with spironolactone competing with aldosterone for cardiac mineralocorticoid receptors."8.86Aldosterone, hypertension and heart failure: insights from clinical trials. ( Funder, JW, 2010)
" Angiotensin II, the principal effector peptide of the RAAS, has far-reaching effects on vascular structure, growth and fibrosis, and is a key regulator of vascular remodeling and inflammation."8.83Role of the renin-angiotensin-aldosterone system in vascular remodeling and inflammation: a clinical review. ( Duprez, DA, 2006)
"Only recently approved for use in the treatment of hypertension in the US, the beta-adrenergic receptor blocking compound propranolol has been used elsewhere for this purpose since 1964."8.75Pathophysiology of propranolol in hypertension. ( Frohlich, ED, 1977)
" It has been reported that sPRR functions as an important regulator of intrarenal renin contributing to angiotensin II (ANG II)-induced hypertension."8.31Mutagenesis of the cleavage site of (pro)renin receptor abrogates aldosterone-salt-induced hypertension and renal injury in mice. ( Chen, Y; Fu, Z; Kaewsaro, K; Lambert, J; Yang, T; Zheng, H, 2023)
"The authors sought to determine the relationship of circulating angiotensinogen levels to ethnicity, sex, BP, incident hypertension, and prevalent hypertension in a modern sex-balanced ethnically diverse cohort."8.31Blood Levels of Angiotensinogen and Hypertension in the Multi-Ethnic Study of Atherosclerosis (MESA). ( Brambatti, M; Carlisle, SM; DeFilippis, AP; Kahlon, T; Michos, ED; Morgan, ES; Mostacero, DO; Mousavi, H; Mullick, AE; Ouyang, P; Shah, SJ; Tami, Y; Trainor, PJ; Tsimikas, S, 2023)
"To study the development of microalbuminuria (MAU) in essential hypertension (EHT), we investigated the association of MAU with central blood pressure (CBP), direct renin concentration (DRC), plasma aldosterone (PA), and uric acid (UA)."8.31Central diastolic blood pressure, plasma aldosterone and uric acid are associated with microalbuminuria in essential hypertension: a case-control study. ( Chou, H; Li, J; Li, Y; Shi, L; Wei, M; Yang, N, 2023)
"Activity of the circulating renin-angiotensin-aldosterone system (RAAS) has not been comprehensively characterized in cats with systemic hypertension (SH) or cardiomyopathy (CM), and the effects of furosemide or amlodipine treatment on the RAAS have not been fully evaluated in cats."8.12Circulating renin-angiotensin-aldosterone system activity in cats with systemic hypertension or cardiomyopathy. ( Domenig, O; Guillot, E; Mochel, JP; Ward, JL; Ware, WA; Yuan, L, 2022)
"The saline suppression test (SST) and captopril challenge test (CCT) are commonly used confirmatory tests for primary aldosteronism (PA)."8.02Seated Saline Suppression Test Is Comparable With Captopril Challenge Test for the Diagnosis of Primary Aldosteronism: A Prospective Study. ( Cheng, Q; Du, Z; Feng, Z; He, W; Hu, J; Li, Q; Liu, B; Song, Y; Wang, Z; Xu, Z; Yang, J; Yang, S, 2021)
"We prospectively enrolled 121 patients with confirmed primary aldosteronism who started mineralocorticoid receptor antagonist (canrenone) treatment."8.02Mineralocorticoid Receptor Antagonist Effect on Aldosterone to Renin Ratio in Patients With Primary Aldosteronism. ( Avataneo, V; Bertello, C; Buffolo, F; Burrello, J; D'Avolio, A; Mengozzi, G; Monticone, S; Mulatero, P; Pecori, A; Rabbia, F; Rumbolo, F; Veglio, F, 2021)
"Recent reports described cases of severe hypertension and hypokalemia accompanied by low renin and aldosterone levels during antifungal therapy with posaconazole and itraconazole."7.96Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals. ( Beck, KR; Odermatt, A; Telisman, L; Thompson, GR; van Koppen, CJ, 2020)
"Vascular function, including reactive hyperemia index (RHI), flow-mediated vasodilation (FMD) and nitroglycerine-induced vasodilation (NID), arterial stiffness including brachial-ankle pulse wave velocity (baPWV) and brachial intima-media thickness (IMT) and ROCK activity in peripheral leukocytes were measured before and after 12 weeks of treatment with eplerenone in 50 patients with IHA."7.91Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study. ( Aibara, Y; Chayama, K; Goto, C; Hashimoto, H; Higashi, Y; Kajikawa, M; Kihara, Y; Kishimoto, S; Liao, JK; Maruhashi, T; Matsui, S; Nakashima, A; Noma, K; Oki, K; Takaeko, Y; Yusoff, FM, 2019)
" We report our long-term single-practice experience in 5 patients with chronic hyperaldosteronism (HA, including 3 with glucocorticoid remediable aldosteronism, GRA) treated with low-dose amiloride (a specific epithelial sodium channel [ENaC] blocker) 5-10 (mean 7) mg daily for 14-28 (mean 20) years."7.91Long-term BP control and vascular health in patients with hyperaldosteronism treated with low-dose, amiloride-based therapy. ( Hong, M; Hussain, T; Izzo, JL; Osmond, PJ, 2019)
"The Captopril challenge test (CCT) is an easy-conduct confirmatory test for diagnosing primary aldosteronism (PA)."7.91The captopril challenge test for diagnosing primary Aldosteronism in a Chinese population. ( Feng, WH; Li, HY; Li, P; Zhang, WJ; Zhang, Y; Zhu, DL; Zhu, KY, 2019)
" We report our long-term single-practice experience in an unusual group of five patients with chronic hyperaldosteronism (HA, including three with glucocorticoid-remediable aldosteronism, GRA) treated with low-dose amiloride (a specific epithelial sodium channel [ENaC] blocker) 5-10 (mean 7) mg daily for 14-28 (mean 20) years."7.91Maintenance of long-term blood pressure control and vascular health by low-dose amiloride-based therapy in hyperaldosteronism. ( Hong, M; Hussain, T; Izzo, JL; Osmond, PJ, 2019)
"High salt intake markedly enhances hypertension induced by angiotensin II (Ang II)."7.88Central and peripheral slow-pressor mechanisms contributing to Angiotensin II-salt hypertension in rats. ( Ahmad, M; Blaustein, MP; Hamlyn, JM; Keshtkar-Jahromi, M; Leenen, FHH; Lu, J; Wang, HW, 2018)
"In the PATHWAY-2 study of resistant hypertension, spironolactone reduced blood pressure substantially more than conventional antihypertensive drugs."7.88Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies. ( Brown, MJ; Caulfield, MJ; Cruickshank, JK; Ford, I; MacDonald, TM; Mackenzie, IS; McInnes, GT; Morant, SV; Padmanabhan, S; Salsbury, J; Sever, P; Webb, DJ; Williams, B, 2018)
"Stroke-prone spontaneously hypertensive (SHRSP) rats were administered losartan, amlodipine or saline for 6 or 16weeks at the onset of prehypertension."7.85Early treatment with losartan effectively ameliorates hypertension and improves vascular remodeling and function in a prehypertensive rat model. ( He, DH; Lin, JX; Xie, Q; Xu, CS; Zhang, LM, 2017)
"Activation of angiotensinergic pathways by central aldosterone (Aldo)-mineralocorticoid receptor (MR) pathway plays a critical role in angiotensin II (Ang II)-induced hypertension."7.83Mineralocorticoid and angiotensin II type 1 receptors in the subfornical organ mediate angiotensin II - induced hypothalamic reactive oxygen species and hypertension. ( Ahmad, M; Chen, A; Huang, BS; Leenen, FH; Wang, HW; White, RA, 2016)
"Cross-sectional data of the single-center "Eplerenone in Primary Hyperparathyroidism" trial were used."7.83Parathyroid hormone, aldosterone-to-renin ratio and fibroblast growth factor-23 as determinants of nocturnal blood pressure in primary hyperparathyroidism: the eplerenone in primary hyperparathyroidism trial. ( Belyavskiy, E; Brandenburg, VM; Brussee, H; Catena, C; Fahrleitner-Pammer, A; Gaksch, M; Grübler, MR; März, W; Meinitzer, A; Perl, S; Pieske, B; Pilz, S; Scharnagl, H; Sechi, LA; Tomaschitz, A; Van Ballegooijen, AJ; Verheyen, N; Wetzel, J, 2016)
"Among patients with essential hypertension, circulating endogenous ouabain and Aldo are typically coelevated and their BP is salt-sensitive."7.83Endogenous ouabain and aldosterone are coelevated in the circulation of patients with essential hypertension. ( Brioni, E; Casamassima, N; Hamlyn, JM; Lanzani, C; Manunta, P; Messaggio, E; Simonini, M; Tentori, S; Zagato, L, 2016)
" Anthropometric parameters and aldosterone, plasma renin activity, cortisol, cortisone, Homeostasis Model Assessment Insulin Resistance (HOMA-IR), high-sensitivity C-reactive protein, adiponectin, IL-6, plasminogen activator inhibitor type 1 levels and matrix metalloproteinase-9 and matrix metalloproteinase-2 (MMP-9 and MMP-2) activities were measured."7.83Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension. ( Aglony, M; Allende, F; Bancalari, R; Baudrand, R; Campino, C; Carvajal, CA; Fardella, CE; Fuentes, CA; García, H; García, L; Kalergis, AM; Lagos, CF; Loureiro, C; Martinez-Aguayo, A; Sanhueza, S; Solari, S; Tapia-Castillo, A; Valdivia, C; Vecchiola, A, 2016)
" In this study, we sought to determine if renal denervation (RDN) inhibits aldosterone expression and associated cardiovascular pathophysiological changes in angiotensin II (Ang II)-induced hypertension."7.83Renal denervation attenuates aldosterone expression and associated cardiovascular pathophysiology in angiotensin II-induced hypertension. ( Chen, DR; Chen, J; Gao, PJ; Hong, MN; Li, XD; Ma, Y; Ruan, CC; Wu, YJ; Xu, JZ; Zhu, DL, 2016)
"The objective of this article is to measure serum dehydroepiandrosterone sulfate (DHEA-S) concentration in both genders with primary aldosteronism (PA)."7.81Serum dehydroepiandrosterone sulfate concentration is lower in women with primary aldosteronism. ( Chen, AH; Huang, TS; Li, HY; Lin, YH; Wu, VC, 2015)
"The renal mechanisms responsible for angiotensin II (ANG II)-induced hypertension remain incompletely understood."7.81Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension. ( Li, XC; Miguel-Qin, E; Shull, GE; Zhuo, JL, 2015)
" This study suggests that telmisartan (TEL) can inhibit myocardial fibrosis of hypertensive left ventricular hypertrophy (LVH) through the transforming growth factor-β1 (TGF-β1)/Smad signaling pathway."7.80Telmisartan delays myocardial fibrosis in rats with hypertensive left ventricular hypertrophy by TGF-β1/Smad signal pathway. ( Guan, G; Ma, A; Shao, L; Tian, G; Wang, J; Wang, Y; Zhang, Y, 2014)
" On day 11, hypertension was induced by continuous angiotensin II infusion."7.80M-atrial natriuretic peptide and nitroglycerin in a canine model of experimental acute hypertensive heart failure: differential actions of 2 cGMP activating therapeutics. ( Burnett, JC; Cataliotti, A; Chen, HH; Ichiki, T; McKie, PM; Sangaralingham, SJ, 2014)
" We investigated the effects of upregulating heme-oxygenase (HO) on myocardial histo-pathological lesions, proinflammatory cytokines/chemokines, oxidative mediators and important markers of heart failure such as osteopontin and osteoprotergerin in N(ω)-nitro-l-arginine methyl ester (L-NAME)-induced hypertension."7.80Heme oxygenase suppresses markers of heart failure and ameliorates cardiomyopathy in L-NAME-induced hypertension. ( Chibbar, R; Lane, N; Ndisang, JF, 2014)
"Aim of the study is to evaluate the impact of spironolactone (SPL) on indexes of metabolic syndrome (MS) and further investigate the mechanisms underlying its protective effects."7.79Spironolactone prevents dietary-induced metabolic syndrome by inhibiting PI3-K/Akt and p38MAPK signaling pathways. ( Liang, LY; Lin, YE; Liu, MJ; Long, HD; Zeng, ZH, 2013)
"This study was performed to determine the characteristics and mechanism of hypertension in SHR/NDmcr-cp(+/+) rats (SHRcp), a new model of metabolic syndrome, with a focus on the autonomic nervous system, aldosterone, and angiotensin II."7.79Novel mechanism for disrupted circadian blood pressure rhythm in a rat model of metabolic syndrome--the critical role of angiotensin II. ( Kataoka, K; Katayama, T; Kim-Mitsuyama, S; Koibuchi, N; Maeda, M; Matsui, K; Mingjie, M; Nakagawa, T; Ogawa, H; Sueta, D; Toyama, K; Uekawa, K; Waki, H; Yasuda, O, 2013)
"Circulating angiotensin II (Ang II) activates a central aldosterone-mineralocorticoid receptor neuromodulatory pathway, which mediates most of the Ang II-induced hypertension."7.79Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension. ( Ahmad, M; Huang, BS; Leenen, FH; White, RA, 2013)
"Leptin and aldosterone have been associated with the pathophysiological mechanisms of hypertension."7.79High-circulating leptin levels are associated with increased blood pressure in uncontrolled resistant hypertension. ( Barbaro, NR; de Faria, AP; de Haro Moraes, C; Demacq, C; Ferreira-Melo, SE; Figueiredo, VN; Júnior, HM; Martins, LC; Quinaglia, T; Sabbatini, AR, 2013)
" We report a case of 55-year-old man with primary aldosteronism (PA) whose hyperaldosteronism was suppressed with the PPAR γ agonist pioglitazone."7.79Suppression of primary aldosteronism and resistant hypertension by the peroxisome proliferator-activated receptor gamma agonist pioglitazone. ( Harada, E; Kashiwagi, Y; Mizuno, Y; Morita, S; Shono, M; Yano, M; Yasue, H; Yoshimura, M, 2013)
"In 205 patients with untreated essential hypertension, we measured components of the renin-angiotensin-aldosterone system, plasma levels of fibrinogen, D-dimer, prothrombin fragment 1 + 2 (F1 + 2), and plasminogen activator inhibitor-1 (PAI-1), and assessed cardiac characteristics with standard echocardiography."7.79Association of aldosterone with left ventricular mass in hypertension: interaction with plasma fibrinogen levels. ( Catena, C; Colussi, G; Sechi, LA; Valeri, M, 2013)
" In the present study, we investigated the contribution of aldosterone to the renal p21 expression and senescence during the development of angiotensin II (AngII)-induced hypertension."7.78Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice. ( Deguchi, K; Hitomi, H; Kitada, K; Kobori, H; Lei, B; Masaki, T; Minamino, T; Mori, H; Nakano, D; Nishiyama, A, 2012)
"The aim of this paper is to report a case of unilateral PA with spontaneous remission and reduction of cardiac hypertrophy after long-term spironolactone (SP) therapy."7.78Unilateral primary aldosteronism with spontaneous remission after long-term spironolactone therapy. ( Demura, M; Karashima, S; Kometani, M; Takata, H; Takeda, Y; Yamagishi, M; Yoneda, T, 2012)
"The finding of adipocyte-derived hormone leptin as an overstimulator of sympathetic activity brought a new perspective to the pathophysiological mechanisms of obesity-hypertension."7.78Leptin and aldosterone in sympathetic activity in resistant hypertension with or without type 2 diabetes. ( Boer-Martins, L; Demacq, C; Faria, AP; Figueiredo, VN; Martins, LC; Moraes, Cde H; Moreno, H, 2012)
" Determination of metanephrines by high-pressure liquid chromatography has been well established for the diagnosis of pheochromocytomas, demonstrating high sensitivity and specificity."7.78Plasma and urinary metanephrines determined by an enzyme immunoassay, but not serum chromogranin A for the diagnosis of pheochromocytoma in patients with adrenal mass. ( Deutschbein, T; Hinrichs, J; Mann, K; Petersenn, S; Schmidt, H; Unger, N; Walz, MK, 2012)
"To study on the difference of plasma renin activity (PRA), angiotensin II (Ang II), and aldosterone levels in patients with essential hypertension (EH) or primary aldosteronism (PA) or pheochromocytoma (PHEO), and to analyze the sensitivity and specificity on the diagnosis of PA among patients with hypertension with aldosterone/PRA ratio (ARR)."7.78[Differences of blood plasma renin activity, angiotensin II and aldosterone levels in essential or secondary hypertension]. ( Chen, S; Fu, CL; Li, M; Lu, L; Song, AL; Sun, ML; Tong, AL; Wang, YH; Zeng, ZP, 2012)
"Many studies have implicated both angiotensin II (ANG II) and aldosterone (Aldo) in the pathogenesis of hypertension, the progression of renal injury, and cardiac remodeling after myocardial infarction."7.77Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension. ( Beltz, TG; Gomez-Sanchez, CE; Guo, F; Hay, M; Johnson, AK; Xue, B; Yu, Y, 2011)
"Hypertension was induced in cyp1a1ren-2 transgenic rats by feeding indole-3-carbinol (n = 10) and in Fischer 344 rats by subcutaneously infusing ANG II (n = 7)."7.77Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome. ( Clemetson, KJ; Gebhard, S; Gesell-Salazar, M; Greinacher, A; Hammer, E; Kuttler, B; Peters, B; Peters, J; Rettig, R; Scharf, C; Steil, L; Völker, U, 2011)
" In the present study, the effect of a subdose of fasudil, a selective ROCK inhibitor, on systemic hypertension and myocardium fibrosis induced by aldosterone was investigated in uninephrectomized Sprague-Dawley rats (SD)."7.77Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats. ( Guo, P; Masaki, T; Mori, H; Nishiyama, A; Wu, C, 2011)
" It has been reported that eplerenone has a potential antihypertensive effect, with a profile slightly different from that of spironolactone, and has fewer adverse reactions, suggesting that it may become a first-line treatment for hypertension."7.76Clinical effects of eplerenone, a selective aldosterone blocker, in Japanese patients with essential hypertension. ( Fukuda, S; Sato, A, 2010)
"We, therefore compared, head-to-head, the aldosterone-renin ratio based on PRA with that based on DRA, at baseline and after captopril administration, for identifying aldosterone-producing adenoma (APA) in 251 patients of the Primary Aldosteronism Prevalence in hYpertension Study (PAPY)."7.76The aldosterone-renin ratio based on the plasma renin activity and the direct renin assay for diagnosing aldosterone-producing adenoma. ( Barisa, M; Belfiore, A; Desideri, G; Ferri, C; Letizia, C; Maccario, M; Mantero, F; Morganti, A; Palumbo, G; Patalano, A; Pessina, AC; Roman, E; Rossi, GP; Seccia, TM, 2010)
" The current study was designed to advance our understanding of the therapeutic potential of M-ANP in a canine model of acute angiotensin II-induced hypertension with elevated cardiac filling pressures and aldosterone activation."7.76A novel atrial natriuretic peptide based therapeutic in experimental angiotensin II mediated acute hypertension. ( Boerrigter, G; Burnett, JC; Cataliotti, A; Chen, HH; Ichiki, T; Martin, FL; McKie, PM; Sangaralingham, SJ, 2010)
" To elucidate the potential role of local renin-angiotensin system in aldosterone-induced cardiovascular injury, we investigated the effects of selective mineralocorticoid receptor (MR) antagonist eplerenone (EPL), angiotensin (Ang) II type 1 receptor antagonist candesartan (ARB), and superoxide dismutase mimetic tempol (TEM) on the development of hypertension, vascular injury, oxidative stress, and inflammatory-related gene expression in aldosterone-treated hypertensive rats."7.74Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: the possible role of local renin-angiotensin system. ( Hirata, Y; Hirono, Y; Kobayashi, N; Sakurada, M; Shichiri, M; Sugiyama, T; Suzuki, N; Takai, S; Yoshimoto, T, 2007)
" To elucidate its significance for myocardial fibrosis in the hypertensive heart, we used a mouse model with infusion of angiotensin II and examined results by histology, immunohistochemistry, in situ hybridization, and quantitative real-time reverse transcriptase polymerase chain reaction (RT-PCR)."7.74Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation. ( Hiroe, M; Imanaka-Yoshida, K; Inada, H; Nishioka, T; Onishi, K; Suzuki, M; Takakura, N; Yoshida, T, 2007)
"Renin-angiotensin system gene polymorphisms are associated with essential hypertension; angiotensinogen gene variants are considered potential genetic risk factors."7.74Significance of angiotensinogen gene haplotypes and genotypes combinations in hypertension. ( Goyal, AK; Gupta, M; Javed, S; Kumar, R; Nejatizadeh, A; Pasha, MQ; Stobdan, T, 2008)
"To compare efficacy of use of the blocker of aldosteron receptors spironolactone and diuretic indapamide in low-renin arterial hypertension (AH), their action on blood pressure, serum concentrations of sodium, potassium, creatinine, plasmic renin activity (PRA), plasmic aldosteron concentration (PAC)."7.73[Use of spironolactone and indapamide in the treatment of low-renin arterial hypertension]. ( Bagdonas, G; Kazanavichus, G; Naudzhunas, A; Yankauskene, L, 2006)
" Since chronic inhibition of nitric oxide (NO) synthase with N(omega)-nitro-L-arginine methyl ester (L-NAME) induces systemic hypertension associated with cardiovascular inflammation and remodeling, we examined the potential role of aldosterone in this process using eplerenone, a selective aldosterone receptor antagonist."7.73The antagonism of aldosterone receptor prevents the development of hypertensive heart failure induced by chronic inhibition of nitric oxide synthesis in rats. ( Asano, Y; Fujita, M; Hirata, A; Hori, M; Kitakaze, M; Minamino, T; Okada, K; Sanada, S; Shintani, Y; Takashima, S; Tomoike, H; Tsukamoto, O; Yamasaki, S; Yulin, L, 2006)
"Losartan attenuates BSO-induced hypertension, which appears to be mediated, in part, by angiotensin II and the prostanoid endothelium-derived factors."7.72Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats. ( Abukhalaf, IK; Bayorh, MA; Eatman, D; Ganafa, AA; Silvestrov, N; Socci, RR, 2003)
"The effects of low-dose oral spironolactone (SPIRO) in a rat model of hypertensive heart failure (spontaneously hypertensive heart failure rat) were compared with its effects when combined with captopril (CAP)."7.72Combined effects of low-dose oral spironolactone and captopril therapy in a rat model of spontaneous hypertension and heart failure. ( Bauer, JA; Ghosh, S; Holycross, BJ; Kambara, A; Kwiatkowski, P; McCune, SA; Schanbacher, B; Wung, P, 2003)
"We investigated the pathophysiological role of the cardiac adrenomedullin (AM) system, including the ligand, receptor and amidating activity in the hypertrophied heart in severe hypertension."7.72Upregulation of ligand, receptor system, and amidating activity of adrenomedullin in left ventricular hypertrophy of severely hypertensive rats: effects of angiotensin-converting enzyme inhibitors and diuretic. ( Akimoto, K; Minamino, N; Mori, Y; Nishikimi, T; Tadokoro, K; Wang, X, 2003)
"Functional changes in the kidneys of healthy men with (FH+) (n = 15) and without (FH-) (n = 15) family history of primary arterial hypertension were examined during administration of low-dose exogenous angiotensin II (A2) (1 ng/kg per min) before and after acute (1 mg intravenous enalaprilat) and chronic (7 days oral enalapril, 30 mg/day) angiotensin-converting enzyme (ACE) inhibition."7.72Increased renovascular response to angiotensin II in persons genetically predisposed to arterial hypertension disappears after chronic angiotensin-converting enzyme inhibition. ( Bock, A; Dieterle, T; Drewe, J; Gyr, K; Haberthür, C; Huber, PR; Martina, B; Schächinger, H, 2004)
"There are not studies about the utility of modified liberation doxazosin (MLD) in the combined treatment of the true resistant hypertension (TRH)."7.72[Effect of modified liberation doxazosin on blood pressure, insulin resistance, and catecholamine secretion in patients with true resistant hypertension]. ( Aliaga Martínez, L; Fernández-Torres, C; Jiménez-Alonso, J; Mediavilla García, JD; Sabio, JM, 2004)
"The dual ACE+NEP inhibitor MDL prevented and regressed severe hypertension and cardiovascular damage, even in this model of severe angiotensin II-dependent hypertension with pronounced cardiovascular damage."7.71Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor. ( Agabiti-Rosei, E; Bova, S; Cavallin, M; Mazzocchi, G; Nussdorfer, GG; Pessina, AC; Rizzoni, D; Rossi, GP, 2002)
"Aldosterone-induced hypertension is associated with renal damage that may be mediated by endothelin-1 (ET-1)."7.71Contribution of endothelin-1 to renal activator protein-1 activation and macrophage infiltration in aldosterone-induced hypertension. ( Chen, X; He, G; Schiffrin, EL; Tostes, RC; Touyz, RM, 2002)
"The aim of the study was to compare hypotensive reaction after treatment with enalapril and enalapril with isosorbide mononitrate in patients with mild and moderate hypertension."7.71[Effect of isosorbide mononitrate on hypotensive action of enalapril in patients with mild and moderate hypertension]. ( Przewłocka-Kosmala, M, 2002)
"An increased sensitivity to angiotensin II (Ang II) has been observed in patients with established hypertension."7.71Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension. ( Delles, C; Jacobi, J; Klingbeil, AU; Schlaich, MP; Schmidt, BM; Schmieder, RE; Schneider, MP, 2002)
"Spironolactone is a safe, effective therapy for patients with refractory hypertension."7.71The role of spironolactone in the treatment of patients with refractory hypertension. ( Carré, E; Lincoff, AM; Mertes, M; Ouzan, J; Pérault, C, 2002)
" The antistroke effects of captopril treatment occurred without an antihypertensive effect, weren't altered by enhancing hypertension during treatment (with dexamethasone), and couldn't be duplicated by antihypertensive treatment with hydralazine."7.70Effect of poststroke captopril treatment on mortality associated with hemorrhagic stroke in stroke-prone rats. ( King, SR; Smeda, J; Vasdev, S, 1999)
"Clinical evaluation of hypotensive effectiveness and the cardiovascular and side effects of enalapril monotherapy of significant essential hypertension (SEH) in adolescents was performed."7.69[Evaluation of the efficacy and safety of monotherapy for significant essential hypertension in adolescents with use of enalapril]. ( Cichocka, E; Januszewicz, P; Kawalec, W; Wyszyńska, T, 1995)
"Flosequinan (BTS 49465, 7-fluoro-1-methyl-3-methyl-sulphinyl-4-quinolone), a recently direct-acting vasodilator that should cause relatively less reflex tachycardia, was given in a single oral dose of 200 mg to 10 untreated patients with moderate to severe hypertension."7.69Acute effects of flosequinan (BTS 49465) in untreated moderate to severe hypertension. ( Janssen, MC; Reyenga, J; Smits, P; Thien, T, 1995)
"Ten cases of adrenal adenomas, one case with unilateral adrenal hyperplasia, and another case with apparent bilateral are reported, in whom an alternative pathway of aldosterone via 21-deoxyaldosterone is operative."7.69A new subset of mineralocorticoid hypertension with excess of 21-deoxyaldosterone and Kelly's-M1 steroid: clinical and morphological findings. ( Abdelhamid, S; Bönhof, JA; Haack, D; Lewicka, S; Müller-Lobeck, H; Nensel, U; Pahl, S; Remberger, K; Röckel, A; Vecsei, P, 1995)
" To define possible cellular mechanisms involved in central mineralocorticoid action, benzamil, an amiloride analogue with selective affinity for the Na+ channel, was continuously infused intracerebroventricularly in three mineralocorticoid-dependent hypertension models in Sprague-Dawley rats, the continuous subcutaneous infusion of aldosterone, the intracerebroventricular infusion of aldosterone, and the ingestion of carbenoxolone, a synthetic licorice analogue."7.69Effect of central amiloride infusion on mineralocorticoid hypertension. ( Gomez-Sanchez, CE; Gomez-Sanchez, EP, 1994)
" Study 1: A long-term (4 weeks) treatment with slow-release nifedipine (Nif), 40-60 mg/day, was performed in 9 in-patients with essential hypertension (EHT)."7.69[Mechanism of inhibition of aldosterone secretion by a Ca2+ channel blocker in patients with essential hypertension and patients with primary aldosteronism]. ( Iimura, O; Shimamoto, K; Yokoyama, T, 1995)
"Approximately half of Caucasian patients with essential hypertension and with hyperaldosteronism exhibit elevated circulating levels of endogenous ouabain."7.69Immunoreactive endogenous ouabain in primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels. ( De Toni, R; Hamlyn, JM; Manunta, P; Pavan, E; Pessina, AC; Rossi, G; Semplicini, A, 1995)
"The present study aimed to assess the influence of a highly industrialized environment on the prevalence of arterial hypertension and plasma levels of cholesterol, uric acid, aldosterone and plasma renin activity."7.69Does industrial environment influence the prevalence of arterial hypertension, plasma cholesterol and uric acid concentration and activity of the renin-aldosterone system? ( Kokot, F; Wiecek, A, 1996)
" Tsukuba hypertensive mice (THM) carry both human renin and angiotensinogen genes, and develop hypertension."7.69Development of polyuria in Tsukuba hypertensive mice carrying human renin and angiotensinogen genes. ( Fukamizu, A; Ikemoto, F; Mino, N; Murakami, K; Nishikibe, M; Tsuchida, M; Uehara, S, 1995)
"Myocardial fibrosis, associated with increased expression of angiotensin converting enzyme (ACE) and bradykinin (BK) receptor binding at sites of tissue repair, accompanies chronic elevations in circulating angiotensin II (AngII) and/or aldosterone (ALDO) that simulate chronic cardiac failure."7.69Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion. ( Ramires, FJ; Sun, Y; Weber, KT, 1997)
"We have investigated the possible involvement of endogenous corticosteroids in the maintenance of hypertension in aged lean and obese Zucker rats using the type II corticosteroid antagonist mifepristone."7.69Effects of the glucocorticoid II receptor antagonist mifepristone on hypertension in the obese Zucker rat. ( Clapham, JC; Turner, NC, 1997)
"The present study was designed to investigate the effect of L-arginine administration on patients with essential and secondary hypertension by measuring haemodynamic parameters, neuroendocrine hormones and indicators of nitric oxide (NO) release."7.68Role of L-arginine-nitric oxide pathway in hypertension. ( Hishikawa, K; Kato, R; Nakaki, T; Saruta, T; Suzuki, H, 1993)
"Vascular permeability of the coronary and mesenteric circulation is increased in association with the arterial hypertension that accompanies either endogenous activation of the renin-angiotensin-aldosterone system (RAAS) or exogenous administration of angiotensin II (AII)."7.68Coronary microvascular fluid flux and permeability: influence of angiotensin II, aldosterone, and acute arterial hypertension. ( Campbell, SE; Janicki, JS; Reddy, HK; Weber, KT; Zhou, G, 1993)
"A case of primary aldosteronism treated with spironolactone therapy has been followed up for 24 years."7.68Twenty-four year spironolactone therapy in an aged patient with aldosterone-producing adenoma. ( Hashimoto, T; Ito, Y; Koshida, H; Miyamori, I; Morimoto, S; Morise, T; Takeda, R; Yamazaki, T, 1992)
"The effect of manidipine on cardiac hypertrophy, coronary circulation, left ventricular weight and maximal coronary flow in hypertension was measured in DOCA/salt treated systolic hypertensive rats with and without manidipine treatment."7.68Effect of manidipine on cardiac hypertrophy and coronary circulation in DOCA/salt hypertensive rats. ( Asayama, J; Itoh, H; Kuwabara, T; Nakagawa, M; Nakata, T; Sasaki, S; Takeda, K; Takesako, T; Tanabe, S; Yamahara, Y, 1992)
"The effect of treatment of hypertension with nifedipine on plasma renin activity, blood serum level of aldosterone in the course of renin test, and cortisol and growth hormone concentrations after stimulation with insulin hypoglycemia was followed during two weeks of treatment in 40 patients with essential hypertension."7.68[Effect of nifedipine treatment on the renin-aldosterone system and secretion of cortisol and growth hormone in patients with essential hypertension]. ( Kokot, F; Wnuk, R, 1991)
"To clarify the hemodynamic and endocrine mechanisms of the hypotensive effect of amosulalol, an alpha- and beta-adrenoceptor antagonist, 19 patients with essential hypertension received amosulalol (20-80 mg/day; average 48."7.68Hemodynamic and endocrine changes associated with hypotensive action of amosulalol in essential hypertension. ( Ando, K; Fujita, T; Noda, H; Ogata, E, 1992)
"Aim of this study was to assess the relationship between plasma concentration of atrial natriuretic factor (ANF) and its two-dimensional echocardiographic (left ventricular mass, left atrium diameter) and humoral (plasma renin and aldosterone) variables in essential hypertension (EH)."7.68Atrial natriuretic factor in essential hypertension: echocardiographic and humoral correlates. ( Favilla, S; Lattanzi, F; Lucarini, AR; Marini, C; Salvetti, A; Urbani, MP, 1992)
"This study was conducted to elucidate renal uric acid metabolism in patients with primary aldosteronism (PA;16 cases) as compared with normotensive subjects (NT;25 cases) and essential hypertensives (EHT;51 cases)."7.68[Study on uric acid metabolism in patients with primary aldosteronism]. ( Iimura, O; Kikuchi, K; Komura, H; Marusaki, S; Namba, M; Ohtomo, T; Satoh, N; Suzuki, S; Takada, T, 1992)
"Urinary excretion of 18-hydroxycortisol (18-OHF), 18-hydroxycorticosterone (18-OHB) and aldosterone 18-glucuronide (Aldo-18-glu) was measured in 10 patients with primary aldosteronism; 5 with aldosterone-producing adenoma (APA) and 5 with idiopathic hyperaldosteronism (IHA), 10 patients with essential hypertension (EHT) and 11 normotensive subjects."7.68Determination of urinary 18-hydroxycortisol in the diagnosis of primary aldosteronism. ( Iki, K; Itoh, Y; Miyamori, I; Takasaki, H; Takeda, R; Takeda, Y, 1992)
"Plasma concentrations of renin and aldosterone were measured before and 60 min after taking 25 mg captopril in 242 patients with arterial hypertension (124 men, 118 women, aged 51."7.68[Does the captopril test improve the diagnosis of primary hyperaldosteronism?]. ( Bönner, G; Degenhardt, S; Grimm, U; Krone, W; Stimpel, M; Wambach, G, 1992)
" In 10 patients with essential hypertension, we investigated the influence of betaxolol, a selective beta 1-adrenergic blocking agent, on renal function and on plasma levels of ANP during exercise, volume depletion and volume expansion."7.68Influence of betaxolol on renal function and atrial natriuretic peptide in essential hypertension. ( Grabensee, B; Heering, P; Hollenbeck, M; Kutkuhn, B; Plum, J, 1991)
"Plasma levels of atrial natriuretic factor were measured in 71 patients with essential hypertension and 13 with borderline arterial hypertension by using radioimmunoassay."7.68[Atrial natriuretic factor in patients with hypertension]. ( Bil'chenko, AV; Vasil'ev, IuM, 1991)
"130 cases of patients with essential hypertension (EH) and 70 cases of normal subjects were researched for correlation between TCM differential types and plasma levels of renin, angiotension II, aldosterone, atrial natriuretic factor (ANF) in patients with EH."7.68[Relation between traditional Chinese medicine differential types and plasma levels of renin, angiotension II, aldosterone, atrial natriuretic factor in patients with essential hypertension]. ( Li, H, 1991)
"Plasma levels of atrial natriuretic peptide (ANP) were measured in patients with normal renin essential hypertension (n = 12), low renin essential hypertension (n = 11) and primary aldosteronism due to aldosterone producing adenoma (APA, n = 8) and idiopathic hyperaldosteronism (IHA, n = 3) after overnight rest in the supine position and after 4 h upright posture and furosemide administration."7.68Dissociation of plasma atrial natriuretic peptide responses to upright posture and furosemide administration in patients with normal-, low renin essential hypertension and primary aldosteronism. ( Fütö, L; Gláz, E; Gutkowska, J; Kiss, R; Rácz, K; Sergev, O; Varga, I, 1991)
"To study the effects of a novel angiotensin I converting enzyme inhibitor (ACEI) on hypertension-induced cardiac hypertrophy, benazepril hydrochloride (CGS 14824 A, CAS 86541-74-4) at the dose of 3 and 10 mg/kg/d p."7.68Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneously hypertensive rats. ( Hasegawa, Y; Inukai, T; Katahira, J; Nakao, K; Takemori, E, 1991)
"0% by weight) of the neutral amino acid, L-tryptophan, on the development of hypertension during chronic exposure to cold."7.68Effect of chronic dietary treatment with L-tryptophan on the development of cold-induced hypertension in rats. ( Baron, A; Cade, JR; Fregly, MJ; Riesselmann, A, 1991)
"An attenuation of adrenergic activity during the inhibition of endogenous angiotensin II formation was evaluated by determining plasma norepinephrine concentration after a single oral administration of captopril compared to that after nifedipine in essential hypertension."7.68Captopril attenuates reflex adrenergic response in essential hypertension. ( Masuyama, Y; Mohara, O, 1991)
"The effects of the mineralocorticoid antagonist mespirenone on the development and maintenance of aldosterone-induced hypertension in Sprague-Dawley rats has been studied."7.68Effect of a new mineralocorticoid antagonist mespirenone on aldosterone-induced hypertension. ( Agarwal, M; Kalimi, M; Opoku, J; Qureshi, D, 1991)
"This case of Conn's syndrome demonstrates long-term (seven years) efficacy of triamterene-thiazide therapy in controlling both hypertension and hypokalemia."7.68Long-term medical management of aldosterone-producing adenoma. ( Bornemann, M, 1990)
" They investigated therefore in 15 patients with essential hypertension (EH) and in three patients with pheochromocytoma the urinary excretion of free noradrenaline (NA), adrenaline (A) and dopamine (DA), the plasma renin activity (PRA), the aldosterone concentration (PAC) and atrial natriuretic factor (ANF) in plasma, using radioimmunoanalysis, always before and 24 hours after clonidine administration (Haemiton retardR) by the oral route."7.68[The effect of clonidine on humoral factors in patients with arterial hypertension]. ( Dvoráková, J; Gregorová, I; Horký, K; Kopecká, J; Poliak, M, 1990)
"Atrial natriuretic factor (ANF) may play a role in the regulation of the changes of blood volume and vascular reactivity during pregnancy and when pregnancy is complicated by hypertension."7.68Plasma atrial natriuretic factor levels during normal pregnancy and pregnancy complicated by diabetes mellitus and hypertension. ( Atkinson, AB; McCance, DR; McKnight, JA; Roberts, G; Sheridan, B; Traub, AI, 1990)
"This study investigated the ability of two diuretics, amiloride and frusemide, to prevent the development of ACTH induced hypertension in conscious sheep."7.68Amiloride blocks the onset of ACTH-induced hypertension in the sheep. ( Coghlan, JP; Reid, AF; Scoggins, BA; Whitworth, JA, 1990)
"The plasma aldosterone (A) and desoxycorticosterone (DOCS) levels were measured in 10 patients with primary aldosteronism and in 2 subgroups with low-renin hypertensive disease (LRHD): (1) those with normal adrenal glands++ (n - 11) and (2) those with structural changes in the cortex (n - 11)."7.68[Plasma mineralocorticoids--aldosterone and desoxycorticosterone-- in patients with"low-renin"arterial hypertension]. ( Bulkina, OS; Gorbacheva, ON; Levitskaia, IuV; Obtrakht, NV; Sokolova, RI; Ustinova, SE, 1990)
"There is evidence of crucial central nervous system involvement in the pathogenesis of mineralocorticoid-excess salt hypertension, as well as data indicating that corticosterone is the predominant ligand for the type I adrenocorticoid receptor in the brain."7.68ICV infusion of corticosterone antagonizes ICV-aldosterone hypertension. ( Fort, C; Gómez-Sánchez, EP; Thwaites, D; Venkataraman, MT, 1990)
"Initial experiments demonstrated that a 1-h infusion of 10 ng/min angiotensin II (ANG II) into rats causes an increase in plasma aldosterone concentration (PAC) and that chronic administration of aldosterone alone to rats on increased sodium intake causes hypertension."7.68Role of aldosterone in angiotensin II-induced hypertension in rats. ( Fink, GD; Kanagy, NL; Pawloski, CM, 1990)
"Ten male patients with essential hypertension were studied on a constant diet (100 mEq of sodium daily) while on placebo, immediately following a 20-mg oral dose of nitrendipine, and during 1 week of nitrendipine therapy (10 mg twice daily)."7.67Renal effects of nitrendipine monotherapy in essential hypertension. ( Barrett, JD; Eggena, P; Golub, MS; Sambhi, MP; Thananopavarn, C, 1984)
"The converting enzyme inhibitor enalapril, in single daily doses of 10 to 40 mg, was given to 20 hypertensive patients with renal artery stenosis."7.67Enalapril in treatment of hypertension with renal artery stenosis. Changes in blood pressure, renin, angiotensin I and II, renal function, and body composition. ( Brown, JJ; Cumming, AM; Davies, DL; East, BW; Hodsman, GP; Lever, AF; Morton, JJ; Murray, GD; Robertson, JI, 1984)
"Enalapril lowers blood pressure both acutely and during long-term therapy in patients with essential hypertension."7.67Plasma enalapril levels and hormonal effects after short- and long-term administration in essential hypertension. ( Casley, D; Cubella, R; Jackson, BJ; Johnston, CI; Larmour, I, 1984)
"Forty to fifty percent of patients with essential hypertension are unable to modify their adrenal and renal vascular responses to angiotensin II with changes in sodium intake."7.67Converting enzyme inhibitors normalize the reduced adrenal responsiveness to angiotensin II in essential hypertension. ( Hollenberg, NK; Williams, GH, 1984)
"The dependence of arteriolar vasoconstrictor tone on the activity of Na+,K+-ATPase was studied in 17 normotensive subjects (NT) and 28 patients with essential hypertension (EH) by measuring the response in forearm blood flow and vascular resistance to intraarterial infusion of the Na+,K+-ATPase inhibitor ouabain."7.67Forearm vasoconstrictor response to ouabain: studies in patients with mild and moderate essential hypertension. ( Bolli, P; Bühler, FR; Hulthén, UL; Kiowski, W, 1984)
" Furthermore, acute and chronic administrations of clonidine were used to determine a participation of the sympathetic nervous system in the maintenance of hypertension in these patients."7.67Plasma catecholamines and autonomic nervous system function in patients with early renal insufficiency and hypertension: effect of clonidine. ( Campese, VM; Levitan, D; Massry, SG; Romoff, M, 1984)
"The converting-enzyme inhibitor captopril (25-50 mg orally every 6 h for 66 h) was used to dissociate the circulating levels of angiotensin II (ANG II) from changes in sodium balance in 11 patients with normal renin essential hypertension on 10 mmol of sodium/day intake."7.67Captopril enhances vascular and adrenal responsiveness to angiotensin II in essential hypertension. ( Dluhy, RG; Gordon, MB; Hollenberg, NK; Koletsky, RJ; LeBoff, MS; Moore, TJ; Williams, GH, 1984)
"Treatment of fifteen patients with essential hypertension over four weeks using the beta 1-adrenoceptor blocking agent, metoprolol, resulted in a decrease in 24 h urinary excretion of kallikrein and aldosterone along with a decrease in plasma renin activity."7.67Effect of metoprolol on 24-hour urinary excretion of adrenal steroids and kallikrein in patients with essential hypertension. ( Fritschka, E; Gotzen, R; Kittler, R; Schöneshöfer, M, 1984)
"Timolol, a non-cardioselective beta-blocking agent, was administered orally after 2 weeks of placebo to 14 patients with essential hypertension for 8 weeks following 1-4 weeks of dose-ranging period."7.67Effects of timolol on blood pressure, systemic hemodynamics, plasma renin activity, and glomerular filtration rate in patients with essential hypertension. ( Bedogna, V; Fabris, A; Gammaro, L; Maschio, G; Ortalda, V; Tessitore, N; Valvo, E, 1984)
"Studies were carried out in 15 patients with renal insufficiency and hypertension to compare the long-term effects of methyldopa and propranolol on renal hemodynamics."7.67Comparison of long-term renal hemodynamic effects of methyldopa and propranolol in patients with hypertension and renal insufficiency. ( Alterman, L; Bank, DE; Bank, N; Lowenstein, I; Zelen, R, 1984)
"Blood pressure, plethysmographically determined muscle blood flow in the calf at rest and during maximal dilatation, plasma renin activity, angiotensin II and plasma and urinary aldosterone were determined in normotensive men with a positive family history of hypertension (n = 17) and in an age- and weight-matched control group (n = 15) during usual sodium intake and after four weeks of increased salt intake."7.67Calf muscle haemodynamics and the renin-angiotensin-aldosterone system in normotensive subjects with a familial predisposition to hypertension: changes during increased salt intake. ( Andersson, OK; Aurell, M; Berglund, GL; Gudmundsson, O; Wikstrand, JM, 1984)
"Aldosterone responses to posture and the dopamine antagonist, metoclopramide, were studied in seven normotensive controls and 12 patients with essential hypertension."7.67Enhanced response of plasma aldosterone to metoclopramide in essential hypertension. ( Eshkol, A; Lunenfeld, B; Rosenthal, T; Sowers, JR; Stern, N; Tuck, M, 1984)
"The responsiveness of plasma aldosterone to the infusion of angiotensin II at dose rates of 2, 4, and 10 ng/kg X min was assessed in 11 normal subjects and 13 patients with mild essential hypertension before and after 4 weeks of treatment with the sympatholytic agent debrisoquine."7.67Relationship between plasma aldosterone and angiotensin II before and after noradrenergic inhibition in normal subjects and patients with mild essential hypertension. ( Beretta-Piccoli, C; Bianchetti, MG; Boehringer, K; Link, L; Morton, JJ; Weidmann, P, 1984)
"A 46-year-old woman with hypertension, normokalemia, suppressed renin, normal catecholamines, and a left adrenal mass on the CT scan was found to have excessive 18-hydroxycorticosterone (18-OHB) and normal aldosterone levels in plasma, both of which responded poorly to sodium restriction and angiotension II, and supranormally to ACTH."7.67Adrenal adenoma with 18-hydroxycorticosterone excess and hypertension: a variant of aldosteronomas. ( Azukizawa, S; Hosojima, H; Imaizumi, N; Kigoshi, T; Morimoto, S; Uchida, K; Yamamoto, I, 1984)
"A single dose of doxazosin, a long-acting postsynaptic alpha 1-adrenoceptor antagonist, was administered to seven patients with essential hypertension."7.67Antihypertensive effects and pharmacokinetics of single and consecutive administration of doxazosin in patients with mild to moderate essential hypertension. ( Kaneko, Y; Miyajima, E; Miyakawa, T; Shionoiri, H; Takagi, N; Umemura, S; Yasuda, G; Yoshimura, H, 1987)
"The principal aim of this study was to investigate the effects of ketanserin on peripheral vascular pressor mechanisms in nine patients with essential hypertension, including an assessment of the responsiveness to intravenous infusions of the alpha 1-adrenergic agonist, phenylephrine, and the nonadrenergic vasoconstrictor, angiotensin II."7.67Effects of ketanserin on peripheral vascular pressor mechanisms in essential hypertension. ( Donnelly, R; Elliott, HL; Reid, JL, 1988)
" Eight patients with essential hypertension were challenged with an infusion of 32 mmol of potassium chloride in saline before and after control of their blood pressure by the angiotensin converting-enzyme (ACE) inhibitor enalapril."7.67Effect of angiotensin converting-enzyme inhibition on potassium-mediated aldosterone secretion in essential hypertension. ( Barnes, JN; Drew, PJ; Furniss, SS; Goodwin, FJ; Holly, JM; Knight, AR; Skehan, JD, 1985)
"Glomerular filtration rate (GFR) and tubular function were measured by means of the lithium clearance technique in 14 patients with renovascular hypertension (RVH) and eight patients with essential hypertension (EH) before and after oral administration of captopril 25 mg."7.67Abnormal glomerular and tubular function during angiotensin converting enzyme inhibition in renovascular hypertension evaluated by the lithium clearance method. ( Amdisen, A; Danielsen, H; Eiskjaer, H; Hansen, HH; Jensen, FT; Jespersen, B; Madsen, B; Nielsen, HK; Pedersen, EB; Sørensen, SS, 1989)
"The author reviews contemporary views on the pathogenetic participation of selected humoral factors (of the renin-angiotensin-aldosterone system, natriuretic hormone and atrial natriuretic factor) in the development of arterial hypertension in humans."7.67[Humoral mechanisms in the pathogenesis of arterial hypertension with emphasis on the renin-angiotensin-aldosterone system and natriuretic substances]. ( Horký, K, 1989)
"The relationship between atrial natriuretic factor (ANF), the renin-aldosterone axis, and blood pressure reduction with weight loss was investigated in 18 obese subjects (five hypertensive and 13 normotensive) placed on a 12-week, low-sodium (40 mmol), weight-reducing diet."7.67Weight reduction decreases atrial natriuretic factor and blood pressure in obese patients. ( McMurray, RW; Vesely, DL, 1989)
"Nine hypertensive patients with mild to moderate renal dysfunction were entered into a protocol to assess the blood pressure, humoral and renal effects of the angiotensin converting enzyme inhibitor, Benazepril (CGS14824A, 2 to 20 mg twice daily) in patients with hypertension and moderate renal insufficiency (mean creatinine clearance 56 ml/min/1."7.67Effect of benazepril monotherapy in subjects with hypertension associated with renal dysfunction. ( Bauer, JH; Lau, A; Reams, GP, 1989)
"Effects of a single administration of captopril on plasma and urinary vasopressin (AVP) were examined in 8 normotensive (NT) female volunteers, 17 patients with essential hypertension (EHT) and 2 patients with primary aldosteronism (PA)."7.67Effect of single-administration captopril on plasma and urinary vasopressin in normotensive subjects and patients with essential hypertension and primary aldosteronism. ( Fujishima, M; Kimura, Y; Muratani, H; Nakao, Y; Takishita, S; Tomita, Y; Tsuchihashi, T; Ueno, M, 1989)
"In 16 patients with essential hypertension the effects of enalapril 20 mg once daily were compared with those of atenolol 50 mg once daily, with the two drugs in combination and with placebo using a double-blind cross-over design with allocation of treatment order by randomised Latin squares."7.67Enalapril and atenolol in essential hypertension: attenuation of hypotensive effects in combination. ( Bune, AJ; Cain, MD; Chalmers, JP; Morris, MJ; Russell, AE; Southgate, DO; West, MJ; Wing, LM, 1988)
"The effects of ovine corticotropin releasing factor (o-CRF) on plasma aldosterone, 18-OH-corticosterone (18-OHB), plasma adrenocorticotropin (ACTH) and cortisol were determined in eight patients with primary aldosteronism, six with aldosterone-producing adenoma (APA) and two with idiopathic hyperaldosteronism (IHA)."7.67Effects of corticotropin-releasing factor (CRF) on aldosterone and 18-hydroxycorticosterone in essential hypertension and primary aldosteronism. ( Ikeda, M; Koshida, H; Matsubara, T; Miyamori, I; Morise, T; Okamoto, S; Takeda, R; Takeda, Y; Vecsei, P; Yasuhara, S, 1987)
"This study was designed to examine the mechanisms that contribute to the chronic hypotensive effects of verapamil during angiotensin II-induced hypertension."7.67Chronic hypotensive effects of verapamil in angiotensin hypertension are steroid independent. ( Lohmeier, TE; Montani, JP; Rushing, EL; Smith, MJ, 1989)
"Thirteen patients with hypertension and normal renal function received nitrendipine, a calcium entry blocker."7.67Nitrendipine, a calcium-entry blocker. Renal and humoral effects in human arterial hypertension. ( Bravo, EL; Fouad, FM; Pedrinelli, R; Tarazi, RC; Textor, SC, 1986)
"To study the effects of Ca antagonists on hypertension induced cardiac and vascular hypertrophy, diltiazem, at the doses of 30 and 60 mg/kg, p."7.67[Effects of diltiazem on developing blood pressure and accompanying cardiac and vascular hypertrophy in SHR]. ( Inamasu, M; Iwasaki, HO; Morita, T; Nagao, T; Narita, H, 1985)
" These studies were performed in patients with essential hypertension who were maintained on a constant sodium intake (100 mmol/day), before and after 5 days of treatment with ibopamine, an orally active dopamine analogue."7.67Dopaminergic control of aldosterone secretion is not mediated by atrial natriuretic factor in patients with essential hypertension. ( Ambrosi, B; Ardeleani, G; Ferraris, P; Morganti, A; Quorso, P; Sala, C; Venegoni, P; Zanchetti, A, 1988)
" The present study evaluated plasma beta-endorphin, ACTH, cortisol, and aldosterone levels in patients with IHA (n = 10), aldosterone-producing adenomas (n = 4), essential hypertension (n = 11), and normal subjects (n = 10)."7.67Plasma beta-endorphin levels in primary aldosteronism. ( Berelowitz, B; Griffing, GT; Hudson, M; Manson, JA; McIntosh, T; Melby, JC; Salzman, R, 1985)
"The purpose of this study was to evaluate the natriuretic effect and renal haemodynamic changes induced by enalapril in patients with essential hypertension."7.67Natriuretic effect and changes in renal haemodynamics induced by enalapril in essential hypertension. ( Brito, M; Gilbert, HB; Giménez, M; Marcó, E; Moledo, LI; Raffaele, P; Sánchez, RA, 1985)
"In 15 patients with mild-to-moderate essential hypertension a new orally active angiotensin converting enzyme inhibitor, 1-(D-3-acetylthio-2-methylpropanoyl)-L-prolyl-L-phenylalanine (Alacepril), was administered with a single oral dose of 50 mg to evaluate its antihypertensive effect."7.67Acute effects of the new oral angiotensin converting enzyme inhibitor 1-(D-3-acetylthio-2-methylpropanoyl)-L-prolyl-L-phenylalanine (Alacepril) in essential hypertension. ( Fukuchi, S; Hashimoto, S; Kunii, N; Mizuno, K; Niimura, S; Tani, M; Watari, H; Yabe, R, 1985)
"We evaluated the effect of additional chlorthalidone therapy on blood pressure and body fluid volumes in 10 patients with essential hypertension who did not respond to chronic converting enzyme inhibition with enalapril."7.67Changes in blood pressure and body fluid volumes during diuretic therapy in patients with essential hypertension who receive enalapril. ( Geyskes, GG; Mees, EJ; Roos, JC; van Schaik, BA, 1986)
"The angiotensin converting enzyme (ACE) inhibitor captopril proved to be an effective antihypertensive drug during a 5-year follow-up study of patients with severe hypertension who had been resistant to a triple-drug regimen."7.67[Results of a 5-year study with captopril in patients with severe therapy-resistant hypertension]. ( Scheler, F; Schoel, G; Schrader, J, 1986)
"Nifedipine, in a slow release preparation, was given at a mean daily dosage of 47 +/- 4 mg to 12 patients with severe hypertension in whom arterial pressure was not satisfactorily controlled (mean blood pressure, 172 +/- 6/111 +/- 4 mmHg) by the association of a converting enzyme inhibitor and a diuretic."7.67Effect of nifedipine in hypertension not controlled by converting enzyme inhibitor and diuretic. ( Mimran, A; Ribstein, J, 1986)
"0] octane-3-carboxylic acid (ramipril, Hoe 498) were investigated in 10 patients with essential hypertension (WHO stage I or II)."7.67Humoral and blood pressure effects of the angiotensin converting enzyme inhibitor ramipril in essential hypertension. ( Distler, A; Eckert, HG; Haller, H; Irmisch, R; Lenz, T; Metzger, H; Meyer-Sabellek, W; Philipp, T; Tansey, MJ; Wilp, C, 1986)
"Captopril effects were studied in 27 patients with second-stage essential hypertension following administration of a single 25 mg oral dose of the drug."7.67[Mechanisms of the hypotensive action of captopril in essential hypertension]. ( Chernova, NA; Parfenova, EV; Uchitel', IA; Ustinova, SE; Zhukova, IM, 1986)
"Plasma renin activity (PRA) and plasma aldosterone concentration (PAC) were measured in 19 cases with primary aldosteronism (PA) and 72 with essential hypertension (EHT) to differentiate the two disorders in the following conditions: after overnight recumbency (basal state) and after oral administration of captopril."7.67Single oral administration of captopril may not bring an improvement in screening of primary aldosteronism. ( Abe, I; Fujishima, M; Kawasaki, T; Kawazoe, N; Muratani, H; Takishita, S; Tomita, Y; Tsuchihashi, T; Ueno, M, 1987)
"The role of central pressor mechanisms in the maintenance of blood pressure in six hypertensive patients with angiographically proven unilateral renal artery stenosis was investigated by studying the haemodynamic and hormonal responses before and after central sympathetic blockade with clonidine."7.67Cardiovascular and neurohormonal changes following central sympathetic blockade with clonidine in human unilateral renal artery stenosis. ( Kooner, JS; Mathias, CJ; Peart, S, 1988)
"The magnitude of captopril hypotensive effect, and variation in renin-angiotensin-aldosterone and kallikrein-kinin parameters were examined in patients with advanced essential hypertension in the presence of normal and low plasma renin activity."7.67[Changes in the indicators of the renin-angiotensin-aldosterone system, kallikrein-kinin system and arterial blood pressure in elderly patients with essential hypertension treated with captopril]. ( Beuer, E; Brozovskiĭ, KKh; Faulhaber, H; Gurke, R; Khartrodt, V, 1988)
"We investigated the effect of an orally administered, long-acting, beta-adrenergic blocking agent, penbutolol, on the circadian rhythm of blood pressure (BP) and heart rate (HR), and plasma renin activity (PRA), aldosterone (PA) and cortisol (PC) levels in hospital patients with essential hypertension validated by a chronobiological inferential statistic method."7.67Effect of penbutolol on circadian blood pressure, and renin, aldosterone and cortisol levels in patients with essential hypertension. ( Bianconi, M; degli Uberti, EC; Margutti, A; Pansini, R; Portaluppi, F; Rossi, R; Teodori, V; Trasforini, G, 1988)
"The validity of the captopril test for primary aldosteronism (PA) was tested in patients with surgically verified PA (n = 12) or essential hypertension (EHT, n = 20) with different levels of sodium intakes."7.67Effects of sodium intake on the captopril test for primary aldosteronism. ( Iwaoka, T; Naomi, S; Sato, T; Umeda, T, 1987)
"In order to evaluate whether changes in the plasma concentration of aldosterone (PA) following the administration of captopril, an inhibitor of angiotensin-converting enzyme, will establish the diagnosis of primary aldosteronism we have used this test in 9 healthy subjects and in 22 patients with various forms of hypertension, including 5 patients with primary aldosteronism due to idiopathic adrenal hyperplasia (n = 4) or aldosterone-producing adenoma (n = 1)."7.67[Detection of primary aldosteronism using the captopril test]. ( Graninger, W; Nowotny, P; Pirich, K; Vierhapper, H; Waldhäusl, W, 1987)
"The immediate effects of intravenous diltiazem effects and short-term (4 weeks) of the oral drug on systemic and regional hemodynamics, cardiac structure, and humoral responses were evaluated by previously reported methods in nine patients with mild-to-moderate essential hypertension and in one patient with primary aldosteronism."7.67Immediate and short-term hemodynamic effects of diltiazem in patients with hypertension. ( Amodeo, C; Frohlich, ED; Kobrin, I; Messerli, FH; Ventura, HO, 1986)
"The effect of angiotensin converting enzyme inhibition by captopril (CAP) on serum potassium (SK) changes was studied during a three-hour glucose tolerance test (GTT) in recumbent and upright positions in 16 patients with drug-resistant hypertension."7.67Interplay of various factors in glucose-induced hyperkalemia during captopril treatment. ( Bános, C; Gercsák, G; Radó, JP, 1986)
"The influence of long-term nifedipine treatment on body fluid compartments, renal function, the renin-angiotensin system, and the adrenergic system was studied in 18 patients with essential hypertension."7.67Lack of effect of nifedipine on counterregulatory mechanisms in essential hypertension. ( Bruun, NE; Hartling, OJ; Ibsen, H; Moelbak, AG; Nielsen, F; Nielsen, MD, 1986)
"Plasma renin activity (PRA) and plasma aldosterone concentration (PAC) were measured in 19 cases with primary aldosteronism (PA) and in 72 with essential hypertension (EHT) to differentiate the two disorders during the following conditions on normal salt diet: after overnight recumbency (basal state) and 2 hours after oral administration of 25 mg of captopril."7.67Is single oral administration of captopril beneficial in screening for primary aldosteronism? ( Abe, I; Kawasaki, T; Kawazoe, N; Kimura, Y; Muratani, H; Takishita, S; Tomita, Y; Tsuchihashi, T; Ueno, M; Uezono, K, 1986)
"The effect of 8 weeks treatment with the calcium antagonist felodipine--a new long-acting dihydropyridine derivative--in a dose of 10 mg twice daily was studied in 10 male patients with essential hypertension, WHO grade I-II, aged 25-62 years."7.67The effect of 8 weeks treatment with the calcium antagonist felodipine on blood pressure, heart rate, working capacity, plasma renin activity, plasma angiotensin II, urinary catecholamines and aldosterone in patients with essential hypertension. ( Hökfelt, B; Hulthén, UL; Katzman, PL, 1986)
"The effect of exogenous angiotensin II on plasma renin activity (PRA), plasma renin concentration (PRC) and plasma aldosterone (PA) was investigated in a group of 8 patients with essential hypertension after one year of captopril therapy."7.67Effect of exogenous angiotensin II infusion after one year of captopril therapy in essential hypertension. ( Hammond, TG; Miranda, B; Robles, RG; Rodicio, JL; Romero, JC; Ruilope, LM; Sancho, J, 1986)
"7 years, with systemic systolic hypertension were studied before and after 1 month of therapy with oral hydrochlorothiazide, 50 mg/day."7.67Systemic systolic hypertension in the elderly: correlation of hemodynamics, plasma volume, renin, aldosterone, urinary metanephrines and response to thiazide therapy. ( Dunsky, MH; Hill, NE; Mookherjee, S; Smulyan, H; Vardan, S; Warner, RA, 1986)
"Oral administration of felodipine to 10 patients with mild essential hypertension acutely reduced systemic vascular resistance (SVR) by 40% after 30 min."7.67Acute haemodynamic and humoral responses to felodipine and metoprolol in mild hypertension. ( Amery, A; Fagard, R; Lijnen, P; Moerman, E; Staessen, J, 1987)
"Plasma concentrations of arginine vasopressin (AVP), angiotensin II (AII), aldosterone (Aldo), urinary output (V), osmolar clearance (Cosm), free water clearance (CH2O), fractional excretions of sodium (FENa) and potassium (FEK), urinary sodium excretion rate (U-Na) and serum potassium (S-K) were determined in 9 patients with essential hypertension (group I) and 13 normotensive healthy control subjects (group II) before and three times during the first 4 hours after an intravenous injection of 40 mg of furosemide."7.67Abnormal vasopressin and aldosterone response to furosemide in essential hypertension. ( Danielsen, H; Madsen, M; Pedersen, EB; Sørensen, SS; Thomsen, OO, 1986)
"This study assessed renal sodium handling in a group of patients with essential hypertension in whom control of the renal blood supply and aldosterone release by angiotensin II is abnormal ("non-modulating") because of recent evidence that these patients have sodium-sensitive hypertension."7.67Abnormal renal sodium handling in essential hypertension. Relation to failure of renal and adrenal modulation of responses to angiotensin II. ( Hollenberg, NK; Moore, T; Rabinowe, S; Redgrave, J; Shoback, D; Williams, GH, 1986)
"Plasma aldosterone, 18-hydroxycorticosterone (18-OH-B), 18-hydroxydeoxycorticosterone (18-OH-DOC), corticosterone, cortisol and prolactin levels were determined during an angiotensin II infusion at increasing rates both with and without a simultaneous infusion of dopamine in seven normotensive subjects, in ten patients with essential hypertension, and in ten patients with primary aldosteronism."7.67Dopamine reduces aldosterone and 18-hydroxycorticosterone response to angiotensin II in patients with essential low-renin hypertension and idiopathic hyperaldosteronism. ( Lorenz, R; von Werder, K; Weber, PC; Witzgall, H, 1985)
"The effects of chronic dietary salt-loading and nifedipine therapy on hypertension-prone (SBH), -resistant (SBN) and parental (SB) Sabra rats were investigated."7.67Salt-induced hypertension in the 'Sabra' rat strain: influence of nifedipine treatment. ( Ben-Ishay, D; Ebsen, W; Garthoff, B; Kazda, S; Luckhaus, G, 1985)
"Two patients with hypertension due to coarctation of the aorta were treated for 12 weeks with captopril at increasing doses."7.67Resistance to captopril in hypertension of coarctation of the aorta. ( Fallo, F; Mantero, F; Maragno, I, 1985)
"In order to investigate the validity of angiotensin converting enzyme inhibition with captopril as a screening test for primary aldosteronism (PA), 50 mg of captopril were administered orally to 7 patients with PA, 17 with essential hypertension (EH), 5 with renovascular hypertension (RVH), 2 with renoparenchymal hypertension (RH) and 8 normal volunteers."7.67Clinical evaluation of the captopril screening test for primary aldosteronism. ( Fujii, Y; Hamasaki, S; Inoue, J; Iwaoka, T; Miura, F; Naomi, S; Sato, T; Umeda, T, 1985)
"Mean arterial blood pressure, forearm vascular resistance, plasma norepinephrine, plasma renin activity and aldosterone responses to graded lower body negative pressure and tilt at 80 degrees were examined in 10 men with mild to moderate essential hypertension before and after 12 weeks of diltiazem (240 to 360 mg/day) therapy."7.67Effects of diltiazem on hormonal and hemodynamic responses to lower body negative pressure and tilt in patients with mild to moderate systemic hypertension. ( Beck, F; McNamara, C; Mohanty, PK; Sowers, JR; Thames, MD; Welch, B, 1985)
"The responses of plasma renin activity (PRA), plasma bradykinin (BK) and urinary kallikrein like activity (UK) associated with the infusion of angiotensin II (AII) before and after NaCl loading were investigated in pregnancy induced hypertension (PIH)."7.67[Studies on the pathophysiology of pregnancy induced hypertension--endocrinological analysis by the method of angiotensin II and NaCl loading]. ( Mochizuki, M; Morikawa, H; Yamasaki, M, 1985)
"Serum 18-hydroxycorticosterone, aldosterone, and potassium were measured under basal conditions in 34 patients with documented primary aldosteronism, 10 patients with essential hypertension, and 9 normal subjects."7.67The prediction of anatomical morphology of primary aldosteronism using serum 18-hydroxycorticosterone levels. ( Brown, RD; Hanson, CS; Hollifield, JW; Kem, DC; Painton, R; Tang, K; Weinberger, MH, 1985)
"Experiments were performed to characterize the hypertension produced by chronic intracerebroventricular (ICV) infusion of angiotensin II (ANG II) in conscious rats."7.67Sodium-dependent hypertension produced by chronic central angiotensin II infusion. ( Bruner, CA; Fink, GD; Weaver, JM, 1985)
"In earlier studies by our group it was shown that the urinary tetrahydroaldosterone excretion is a more reliable test for the diagnosis of primary aldosteronism than aldosterone-18-glucuronide ('urinary aldosterone')."7.6721-Deoxytetrahydroaldosterone excretion in primary hyperaldosteronism. ( Abdelhamid, S; Lewicka, S; Vecsei, P; Winter, J, 1985)
"0 mg/kg prizidilol HCl, an antihypertensive with vasodilator and beta-adrenoceptor blocking actions, were given to 12 patients with primary hypertension on separate days."7.66Prizidilol, an antihypertensive with precapillary vasodilator and beta-adrenoceptor blocking actions, in primary hypertension. ( Karlberg, BE; Larsson, R; Norlander, B; Wirsén, A, 1981)
"The antihypertensive effect of captopril was tested on 19 patients with essential hypertension, WHO grade I or II."7.66[Captopril in the treatment of essential hypertension (author's transl)]. ( Braun, B; Klaus, D; Lederle, RM, 1980)
" The plasma aldosterone responses to exogenous angiotensin II and adrenocorticotropic hormone (ACTH) were studied before and after 1 month of propranolol therapy (120-240 mg/day) in eight patients with essential hypertension."7.66Effect of propranolol therapy on aldosterone responses to angiotensin II and adrenocorticotropic hormone in essential hypertension. ( Fittingoff, DB; Golub, MS; Tuck, ML, 1981)
"30% of patients with essential hypertension have a decreased adrenal response to angiotensin II (A II) on a low but not a high sodium intake."7.66Decreased adrenal responsiveness to angiotensin II: a defect present in spontaneously hypertensive rats. A possible model of human essential hypertension. ( Braley, LM; Menachery, A; Williams, GH, 1982)
"The humoral and hemodynamic effects of converting enzyme inhibition captopril are presented in two patients with primary hyperaldosteronism (PHA)."7.66Converting enzyme inhibition with captopril in patients with primary hyperaldosteronism. ( Demers, LM; Harrison, TS; Hayes, AH; Luderer, JR, 1982)
"To compare the hemodynamic and humoral effects of increasing doses of captopril, blood pressure, heart rate, plasma renin activity, plasma aldosterone and angiotensin-converting enzyme activity were measured in 10 patients with mild uncomplicated essential hypertension before and after captopril given in an increasing dose of 25, 50 and 100 mg twice a day, with each dose given for 3 days."7.66Humoral and hemodynamic effects of increasing doses of captopril in patients with essential hypertension. ( Abdel-Haq, B; Magagna, A; Pedrinelli, R; Salvetti, A; Sassano, P, 1982)
"Ten milligrams nifedipine was administered orally to young and old persons with or without hypertension, and the acute effects of nifedipine on the renin-angiotensin-aldosterone system were studied one half to 3 hours later."7.66Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension. ( Hiramatsu, K; Kubota, T; Yamada, T; Yamagishi, F, 1982)
"Infusion of angiotensin II into a patient with dexamethasone-suppressible hyperaldosteronism caused a brisk increase in plasma aldosterone concentration."7.6610. Hypertension. A comparison of the effects of angiotensin II infusion and variations in salt intake on plasma aldosterone levels in normal subjects, patients with essential hypertension and patients with hyperaldosteronism. ( Brown, JJ; Fraser, R; Lever, AF; Robertson, JI; Usherwood, T; Zoccali, C, 1983)
"The effects of endralazine, administered intravenously, on blood pressure, heart rate, forearm blood flow, plasma renin activity, aldosterone, adrenaline and noradrenaline were studied in five patients with essential hypertension."7.66Effects of intravenous endralazine in essential hypertension. ( Hoffmann, JJ; Thien, T; van T'Laar, A, 1983)
"Plasma renin activity (PRA), plasma aldosterone (PA), blood uric acid (BUA), plasma concentrations of catecholamines (Pcat) and plasma volume (PV) were measured simultaneously in 24 patients with pregnancy-induced hypertension (PIH)."7.66Plasma renin activity, blood uric acid and plasma volume in pregnancy-induced hypertension. ( Boulanger, JC; Carayon, A; Coevoet, B; Comoy, E; de Fremont, JF; Demory, JE; Desailly, I; Fievet, P; Pleskov, L; Verhoest, P, 1983)
"The response of plasma renin activity (PRA), plasma aldosterone, 18-hydroxycorticosterone (18-OH-B), 18-hydroxydeoxycorticosterone (18-OH-DOC) and corticosterone to furosemide were compared in 20 normal control subjects, 16 patients with normal-renin essential hypertension (NREH) and 12 patients with low-renin essential hypertension (LREH)."7.66Rapid increase of mineralocorticoids after furosemide in low-renin essential hypertension: evidence for 18-hydroxycorticosterone to be a better marker than aldosterone. ( Thayil, G; Weber, PC; Witzgall, H, 1982)
"1 The long-term effects of the oral angiotensin-converting enzyme inhibitor captopril with the addition of a diuretic (chlorthalidone) were examined in 16 patients with moderate or grave hypertension."7.66Long-term captopril treatment in moderate to severe hypertension. ( Aguglia, F; Balsano, F; De Mattia, G; Ficara, C; Santucci, A, 1982)
"The role of the renin-aldosterone axis in mediating responses to antihypertensive treatment was examined in patients with essential hypertension treated with propranolol (n=50) or chlorthalidone (n=50)."7.66The role of aldosterone in the response to treatment of primary hypertension. ( Drayer, JI; Laragh, JH; Purdy, RE; Weber, MA, 1982)
"Paradoxical glucose-induced hyperkalemia (GIH) was elicited exclusively in the upright position during captopril treatment in four hypertensive patients (Group 3) without impaired glucose tolerance in three."7.66Glucose-induced hyperkalemia developing in the upright position in captopril-treated hypertensives. ( Bános, C; Csabuda, M; Gercsák, G; Molnár, Z; Pató, E; Radó, JP, 1982)
"5 mg and 25 mg) of angiotensin I converting enzyme inhibitor (SQ 14,255, captopril) were administered to 8 patients with essential hypertension on a three-crossover study design, and the time course of mean blood pressure (MBP), plasma renin activity (PRA), plasma angiotensin converting enzyme activity (ACE-A), plasma cortisol (PC) and plasma aldosterone (PA) were determined following administration of the drug."7.66Effects of various doses of captopril on plasma aldosterone concentrations in patients with essential hypertension. ( Hatano, M; Honda, M; Izumi, Y, 1982)
"Plasma concentrations and urinary excretion rate of vasopressin (VP) were examined in ten cases of severe hypertension before and during short-term treatment by Captopril (SQ 14225)."7.66Reduction of plasma and urinary vasopressin during treatment of severe hypertension by captopril. ( Aldiger, JC; Corvol, P; Menard, J; Milliez, P; Soto, ME; Thibonnier, M, 1981)
"We investigated changes in the renin-angiotensin-aldosterone system in seven patients with essential hypertension during treatment with captopril (SQ 14225) (300 to 450 mg/day) for 12 months."7.66Captopril in the long-term treatment of essential hypertension: changes in the renin-angiotensin-aldosterone system. ( Hayduk, K; Liebau, G; Riegger, GA; Steilner, H, 1982)
"Plasma volume (PV), extracellular fluid volume (ECV) serum electrolytes, renin and aldosterone were measured before and after 1 week and 4 months of hydrochlorothiazide (HCT) treatment, 50 mg twice daily, in nine male patients with uncomplicated essential hypertension."7.66Body fluid volumes and the response of renin and aldosterone to short- and long-term thiazide therapy of essential hypertension. ( Schalekamp, MA; van Brummelen, P, 1980)
"Twenty-one patients with essential hypertension received a constant infusion of angiotensin II and des-aspartyl1-angiotensin II for 45 min on 2 consecutive days during normal sodium intake."7.66A comparative study on (des-aspartyl1)-angiotensin II and angiotensin II in patients with essential hypertension. ( Fukuchi, S; Mizuno, K; Yamazaki, M, 1980)
"Captopril was given for treatment of hypertension alone or in combination with diuretics to 32 patients for 1- to 4-mo periods."7.66Long-term effects of captopril in hypertension. ( Hata, T; Iwanaga, K; Kumahara, Y; Maruyama, A; Mikami, H; Naka, T; Nakamaru, M; Ogihara, T, 1980)
"The effect of the converting enzyme inhibitor captopril on arterial pressure, the components of the renin-angiotensin-aldosterone system, and body sodium and potassium content was studied in eight hypertensive patients with renal artery stenosis and, in conjunction with diuretics, in seven patients with hypertension unresponsive to previous treatment."7.66Captopril in clinical hypertension. Changes in components of renin-angiotensin system and in body composition in relation to fall in blood pressure with a note on measurement of angiotensin II during converting enzyme inhibition. ( Atkinson, AB; Brown, JJ; Davies, DL; Fraser, R; Kelly, P; Leckie, B; Lever, AF; Morton, JJ; Robertson, JI, 1980)
"Arterial blood pressure and plasma catecholamines, renin activity and aldosterone concentration in 12 patients with severe essential hypertension were studied before and after combined alpha- and beta- adrenoceptor blockade induced by oral labetalol treatment for 2 months."7.66Plasma catecholamines, renin and aldosterone during combined alpha- and beta- adrenoceptor blockade in patients with severe arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Pedersen, A; Pedersen, EB; Pedersen, G, 1980)
"A simultaneous analysis of the interrelationships between mean blood pressure (MBP), plasma catecholamines, plasma renin activity (PRA) and aldosterone, exchangeable body sodium, and blood volume was carried out before and after acute and chronic administration of clonidine in 15 patients with essential hypertension, in order to further elucidate the mechanism(s) of action of this drug."7.66Role of sympathetic nerve inhibition and body sodium-volume state in the antihypertensive action of clonidine in essential hypertension. ( Campese, VM; Massry, SG; Romoff, M; Telfer, N; Weidmann, P, 1980)
"A case of severe hypertension resistant to multiple drug therapy was controlled with minoxidil, captopril, and propranolol hydrochloride after treatment with these drugs alone or in other combinations had failed."7.66Interaction of minoxidil and captopril in the treatment of refractory hypertension. ( Matson, JR; Norby, LH; Robillard, JE, 1981)
"The plasma aldosterone (PA) response to sodium restriction (25 mEq daily for 4 days) and to graded infusions of angiotensin II (AII, 2, 4 and 8 ng/kg/min each for 30 min) during a low-sodium intake were studied in 15 elderly subjects with mild essential hypertension versus 10 elderly normotensive subjects."7.66Plasma aldosterone response to angiotensin II in sodium-restricted elderly subjects with essential hypertension. ( Kigoshi, T; Miyamoto, M; Morimoto, S; Morise, T; Takeda, R; Takimoto, H; Uchida, K, 1981)
"The effect of 5 to 9 days of metyrapone administration (400 mg/m2 every 4 h) on aldosterone, deoxycorticosterone, plasma renin activity, electrolyte balance, and blood pressure was investigated in 2 normotensive siblings (one of whom showed limited ACTH reserve), in 3 patients with hypertension and dexamethasone-suppressible hyperaldosteronism, and in a hypertensive patient with primary hyperaldosteronism due to bilateral adrenal hyperplasia."7.66Mineralocorticoid and metabolic response to metyrapone on normotensive children and children with dexamethasone-suppressible and primary hyperaldosteronism. ( Levine, LS; New, MI; Sonino, N, 1981)
"Plasma aldosterone (PA) responses to sodium restriction (25 mEq sodium/day for 4 days) and to graded angiotensin II (AII) infusions (2, 4 and 8 ng/kg/min each for 30 min) during a low sodium intake were studied in 14 subjects with low renin essential hypertension (LREH) versus 16 normotensive subjects."7.66Aldosterone responsiveness to angiotensin II after sodium restriction in subjects with low renin essential hypertension. ( Fujimura, A; Hashiba, T; Honjo, A; Kigoshi, T; Morimoto, S; Takeda, R; Uchida, K, 1982)
"For distinguishing primary aldosteronism from essential hypertension, we use simple direct radioimmunoassays for "aldosterone" (aldosterone and other materials that react with the antibody to aldosterone) and "18-hydroxycorticosterone" (similarly) in unprocessed urine."7.66Direct radioimmunoassays for "aldosterone" and "18-hydroxycorticosterone" in unprocessed urine, and their use in screening to distinguish primary aldosteronism from hypertension. ( Abdelhamid, S; Benraad, TJ; Haack, D; Hofman, J; Lichtwald, K; Vecsei, P, 1982)
"The most abundant substance in the urinary free steroid fraction of patients with primary aldosteronism has been identified as 18-hydroxycortisol."7.66Hypersecretion of a new corticosteroid, 18-hydroxycortisol in two types of adrenocortical hypertension. ( Chu, MD; Ulick, S, 1982)
"In view of recent evidence that spironolactone may inhibit synthesis of corticosteroids by a direct effect on the adrenal cortex, adrenocortical function was studied in eight patients with essential hypertension who had been treated with spironolactone from 3 months to 14 years."7.66Long term spironolactone and the adrenal cortex in essential hypertension. ( Gorchein, A; Horth, CE; James, VH; Lewis, PS; May, CN, 1980)
"Plasma concentrations of angiotensin II (AII), aldosterone, 18-hydroxycorticosterone and cortisol were measured in seven patients with benign essential hypertension and in seven age-matched control subjects before, and at frequent intervals for 2 h after the intravenous injection of frusemide (40 mg)."7.66Increased 18-hydroxycorticosterone responses to frusemide in essential hypertension. ( Fraser, R; Mason, PA; Semple, PF, 1980)
"Sequential changes in plasma renin activity and urinary aldosterone and noradrenaline were assessed in eight patients with severe hypertension after minoxidil had been added to their treatment."7.66Need for beta-blockade in hypertension reduced with long-term minoxidil. ( Brunner, HR; Ferguson, RK; Gavras, H; Jaeger, P; Jequier, E; Turini, G, 1978)
"To determine the mechanism underlying altered adrenal responsiveness in patients with essential hypertension, the renin-angiotensin-aldosterone axis was assessed in normotensive and hypertensive subjects using three pharmacological probes: SQ 20881, a converting enzyme inhibitor; saralasin, a competitive angiotensin antagonist with prominent agonist properties; and angiotensin itself."7.66The adrenal receptor for angiotensin II is altered in essential hypertension. ( Dluhy, RG; Hollenberg, NK; Moore, TJ; Swartz, SL; Williams, GH, 1979)
") before and during treatment with spironolactone (Sp, 75--100 mg/day) for at least 8 months was studied in 11 patients with essential hypertension."7.66Reduced response of plasma aldosterone to acute ACTH stimulation during long-term treatment with spironolactone in essential hypertension. ( Kim, KS; Miyamori, I; Miyamoto, M; Morimoto, S; Takeda, R; Uchida, K, 1979)
"We substituted minoxidil for dihydralazine in the treatment of 10 patients with refractory hypertension."7.66[Effects of minoxidil on blood pressure and plasma volume in refractory hypertension (author's transl)]. ( Alhenc-Gelas, F; Ménard, J; Morgado Vital, A; Plouin, PF, 1979)
"The plasma aldosterone response to infused angiotensin II was determined in normal controls and in patients with normal renin and with low renin essential hypertension."7.66Enhanced adrenal responsiveness to angiotensin II in patients with low renin essential hypertension. ( Adlin, VE; Channick, BJ; Kanefsky, TM; Marks, AD; Marks, DB, 1979)
"To determine if the abnormally large increases in levels of plasma aldosterone which occur during infusion of angiotensin II in some patients with essential hypertension are due to abnormal decreases in the metabolic clearance of aldosterone, we measured clearances of aldosterone before and during infusion of angiotensin II in 12 patients with essential hypertension and in 10 normal subjects."7.66The metabolic clearance of aldosterone decreases similarly during infusion of angiotensin II in patients with essential hypertension and in normal subjects. ( Brown, RD; Wisgerhof, M, 1979)
"In essential hypertension mean basal (supine) and stimulated plasma renin activity (2 h upright posture + 40 mg furosemide intraveneously) decreased progressively with age."7.66Age- and sex-related differences in plasma aldosterone in essential hypertension. Relationship to plasma renin activity. ( Alasso, I; Glänzer, K; Vetter, H; Vetter, W, 1979)
"Plasma concentrations of angiotensin II (AII) were studied in 36 patients with primary (essential) hypertension and 15 normotensive control subjects during basal (1 h supine rest), upright and frusemide-stimulated (80 mg orally) conditions."7.66Angiotensin II in primary hypertension, relationship to plasma renin activity, aldosterone and urinary electrolytes. ( Karlberg, BE; Tolagen, K, 1979)
"Adrenal responsiveness to angiotensin II (AII) and the diastolic blood pressure responses to saralasin were studied in 19 patients with high renin essential hypertension (HREH) on a 10-meq Na(+)/100 meq K(+) diet."7.66Abnormal adrenal responsiveness and angiotensin II dependency in high renin essential hypertension. ( Bavli, SZ; Dluhy, RG; Hollenberg, NK; Leung, FK; Moore, TJ; Solomon, HS; Williams, GH, 1979)
"3%) the normal, aldosterone-18-glucuronide concentration was clinically misleading, but increased free aldosterone and/or tetrahydroaldosterone values suggested the presence of hyperaldosteronism, which in many of these cases was confirmed by elevated excretion of the possible major aldosterone precursor 18-hydroxycorticosterone (18-OH-B)."7.66Dissociation in the excretion of different aldosterone metabolites and unmetabolized ('free') aldosterone in hypertension. ( Abdelhamid, S; Fiegel, P; Gless, KH; Haack, D; Lichtwald, K; Vecsei, P; Walb, D, 1979)
"Arterial blood pressure and plasma catecholamines, renin activity and aldosterone concentration in 12 patients with severe essential hypertension were studied before and after combined alpha- and beta-adrenergic receptor blockage induced by oral labetalol treatment for 2 months."7.66Effect of oral labetalol on plasma catecholamines, renin and aldosterone in patients with severe arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Pedersen, A; Pedersen, EB; Pedersen, G, 1979)
"The effect of furosemide on urinary kallikrein excretion was studied in 10 patients with essential hypertension and 9 normal volunteer subjects."7.66Effect of furosemide on urinary kallikrein excretion in patients with essential hypertension. ( Abe, K; Chiba, S; Irokawa, N; Ito, T; Kusaka, T; Miyazaki, S; Ritz, K; Saito, K; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K, 1978)
"Studies were undertaken to determine if the dissociation of aldosterone and plasma renin activity in low-renin essential hypertension is due to altered adrenal responsiveness to angiotensin II."7.66Increased adrenal sensitivity to angiotensin II in low-renin essential hypertension. ( Brown, RD; Wisgerhof, M, 1978)
"To determine the influence of dietary sodium intake on the effects of hydrochlorothiazide (HCT) on blood pressure (BP), serum electrolytes, renin and aldosterone, nine male patients with uncomplicated essential hypertension were studied during the following therapeutic regimes: 1) sodium restriction alone (50 mmol/day), 2) sodium restriction combined with HCT (50 MG TWICE DAILY), 3) HCT alone, and 4) sodium restriction combined with HCT."7.66Influence of sodium intake on hydrochlorothiazide-induced changes in blood pressure, serum electrolytes, renin and aldosterone in essential hypertension. ( de Graeff, J; Schalekamp, M; van Brummelen, P, 1978)
"In order to evaluate the relationship between aldosterone status and the blood pressure-lowering effect of spironolactone, 38 patients with essential hypertension were treated with spironolactone (400 mg/day) during one week in hospital on a rigidly sodium-restricted diet."7.66Role of aldosterone in the antihypertensive effect of spironolactone in essential hypertension. ( Benraad, H; Benraad, T; Drayer, J; Hoefnagels, W; Kloppenborg, P, 1978)
"In 34 patients saralasin was infused after variable degrees of sodium depletion in order to differentiate between essential and renin-induced hypertension."7.66[Saralasin-induced changes of blood pressure, renin and aldosterone in essential and renal hypertension (author's transl)]. ( Beyer, J; Hayduk, K; Liebau, G; Steiner, B, 1978)
"The blood pressure response to the angiotensin II analog 1-sar-8-ala-angiotensin II, or saralasin, was studied in five patients with clinical and laboratory evidence of Cushing's syndrome."7.66Evidence for an angiotensinogenic mechanism of the hypertension of Cushing's syndrome. ( Anderson, GH; Dalakos, TG; Elias, AN; Schroeder, ET; Streeten, DH, 1978)
"The effect of indomethacin on plasma renin activity (PRA), urinary aldosterone, 17 OH ketogenic steroids and plasma cortisol was studied in twenty-three patients with essential hypertension and compared in eleven patients to oxprenolol effect by 2 x 2 factorial trial."7.66The effect of indomethacin on plasma renin activity and urinary aldosterone of patients with essential hypertension. ( Arzilli, F; Cavasinni, L; Pedrinelli, R; Poli, L; Salvetti, A; Sassano, P, 1978)
"Adrenal and vascular responsiveness to graded doses of angiotensin II (A II) were recorded for seven normal subjects and 12 patients with essential hypertension while in balance on an intake of 200 mEq sodium/100 mEq potassium."7.65Enhanced aldosterone response to angiotensin II in human hypertension. ( Dluhy, RG; Kisch, ES; Williams, GH, 1976)
"The blood pressure response to propranolol treatment was analyzed retrospectively in 187 patients with benign essential hypertension."7.65Unexpected pressor responses to propranolol in essential hypertension. An interaction between renin, aldosterone and sympathetic activity. ( Case, DB; Drayer, JI; Keim, HJ; Laragh, JH; Weber, MA, 1976)
"To understand the role of the renin-angiotensin-aldosterone system in the pathogenesis of human hypertension, in serial studies we have blocked the system using three different pharmacologic probes: 1) reduction of renin secretion by administration of the beta receptor blocker, propranolol; 2) blockade of the action of angiotensin II by infusion of saralasin, a competitive antagonist of angiotensin II; and 3) blockade of the enzymatic conversion of angiotensin I to angiotensin II by infusing a nonapeptide competitive inhibitor."7.65Blockade of renin or angiotensin for understanding human hypertension: a comparison of propranolol, saralasin and converting enzyme blockade. ( Case, DB; Keim, H; Laragh, JH; Wallace, JM, 1977)
"To investigate the interaction between the renin angiotensin aldosterone system and the renal prostaglandin (PG), urinary excretion of PGE, urinary excretion of main urinary metabolite (MUM) of PGF2a, urinary excretion of aldosterone, and plasma renin activity were measured before and after infusion of 1-Sar-8-Ile-Angiotensin II, a specific competitive inhibitor of angiotensin II, in 18 patients with essential hypertension under normal and low sodium diets."7.65Effects of 1-Sar-8-Ile-angiotensin II on urinary prostaglandin excretion in patients with essential hypertension. ( Abe, K; Chiba, S; Irokawa, N; Ito, T; Otsuka, Y; Ritsu, K; Saito, K; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K, 1977)
"Adrenal responsiveness to angiotensin II was evaluated in patients with "normal-renin" hypertension."7.65Aldosterone regulation in essential hypertension: altered adrenal responsiveness to angiotensin II. ( Dluhy, RG; Moore, TJ; Williams, GH, 1977)
"In 50 patients with essential hypertension treated with chlorthalidone, 100 mg daily for 6 weeks, treatment responders (fall in mean pressure, greater than or equal to 10%) and nonresponders experienced similar weight and electrolyte changes."7.65Disparate patterns of aldosterone response during diuretic treatment of hypertension. ( Drayer, JI; Laragh, JH; Rev, A; Weber, MA, 1977)
"To investigate the role of the renin angiotensin system in the pathogenesis of hypertension in Cushing's syndrome two patients with hypercorticism were infused with 20 mg saralasin (1-sar-8-ala-angiotensin II) over a period of 30 minutes under constant blood pressue control."7.65The effect of saralasin (1sar-8-ala-angiotensin II) on blood pressure in patients with Cushing's syndrome. ( Beckerhoff, R; Cottier, P; Redlich, B; Siegenthaler, W; Vetter, H; Vetter, W, 1976)
"Plasma aldosterone concentration (PAC), plasma renin concentration (PRC), plasma potassium, plasma sodium and blood pressure (BP) have been measured in 22 patients with essential hypertension before and after treatment for one month with alprenolol."7.65Relationship between plasma aldosterone concentration and plasma potassium in patients with essential hypertension during alprenolol treatment. ( Kornerup, HJ; Pedersen, EB, 1976)
"Compared with a group of normal pregnant women, matched for age, parity, posture, and length of gestation, women with hypertension and proteinuria in the last trimester had significantly lower plasma concentrations of renin, renin substrate and angiotensin II."7.65Studies of the renin-angiotension-aldosterone system, cortisol, DOC, and ADH in normal and hypertensive pregnancy. ( Doig, A; Fraser, R; Morton, JJ; Parboosingh, J; Robertson, JI; Weir, RJ; Wilson, A, 1976)
"The responses of blood pressure, plasma renin activity (PRA) and plasma aldosterone concentration (PAC) to infusion of either angiotensin II (10 ng/Kg/min) or norepinephrine (100 ng/Kg/min) were observed in 25 patients with essential hypertension."7.65Effect of pressor agents on blood pressure, plasma renin activity and plasma aldosterone concentration in essential hypertension. ( Yamamoto, Y, 1975)
"Plasma aldosterone, plasma renin activity, sodium and potassium in the plasma and the urine were determinated under acute stimulation with saline-depletion (furosemide) and under acute suppression with saline infusion in 40 patients with primary hypertension stage I, 19 patients with primary hypertension stages II and III, and 11 patients with renal hypertension (chronic glomerulonephritis and chronic pyelonephritis)."7.65[Plasma aldosterone and plasma renin activity in patients with essential and renal hypertension under acute stimulation with saline depletion and acute suppression with saline infusion]. ( Klaus, D; Klumpp, F; Lemke, R; Zehner, J; Zöfel, P, 1975)
"The anti-hypertensive effect of spironolactone and thiabutazide was tested on 47 unselected patients with primary hypertension."7.65[Spironolactone and thiabutazide in the treatment of essential hypertension (author's transl)]. ( Braun, B; Klaus, D; Klump, F; Lemke, R; Zehner, J; Zöfel, P, 1975)
"The response of plasma aldosterone to fludrocortisone administration (400 mug 12-hourly for 3 days) was studied in twenty-two patients with primary hyperaldosteronism."7.65Response of plasma aldosterone to fludrocortisone in primary hyperaldosteronism and other forms of hypertension. ( Allison, ME; Brown, JJ; Ferriss, JB; Fraser, R; Lever, AF; Luke, RG; Padfield, PL; Robertson, JI, 1975)
"Acebutolol, a new cardioselective beta-blocking agent, has been given for 5 days, at a daily dosage of 600 mg to 8 patients with mild essential hypertension."7.65[Effects of acebutolol on the renin-aldosterone system in essential arterial hypertension]. ( Corvol, P; Ménard, J; Plouin, PF, 1975)
" have applied the diazoxide test for the screening of primary hiperaldosteronism to 22 nephropatic patients suffering from hypertension and with different degrees of renal function."7.65[Diazoxide test in the diagnosis of arterial hypertension: modifications in the levels of renin and aldosterone in blood of patients with various restrains of the renal function]. ( Albertini, A; Cecchettin, M; Ghielmi, S; Maiorca, R; Orlandini, A; Signorini, C, 1975)
"Plasma renin activity, arterial and venous angiotensin II (A II), plasma aldosterone, and sodium excretion were measured in a group of 101 patients with mild essential hypertension."7.65Relation between plasma renin activity, angiotensin, and aldosterone and blood pressure in mild untreated hypertension. ( Horvath, JS; Moore, MA; Russell, RP; Walker, WG; Whelton, P, 1976)
"The effect of triamterene, a potassium-retaining natriuretic and diuretic agent, on arterial blood pressure was studied in 31 patients with essential hypertension; there were seven patients with low plasma renin activity and 24 patients with normal plasma renin activity."7.65Triamterene-induced changes in aldosterone and renin values in essential hypertension. Evidence of a role for aldosterone in preventing blood pressure reduction. ( Drayer, JI; Keim, HJ; Laragh, JH; Thurston, H, 1976)
"A 44-year old woman without history of hypertension in her 4 pregnancies was hospitalized for hemoptysia and found to have hypertension 230/120 to 250/150: she had been taking 2 tablets of Lyndiol (5 mg lynestrenol and ."7.65[A case of arterial hypertension imputable to an estroprogestational contraceptive. Implication of the renin-angiotensin-aldosterone system]. ( Béquart, P; Boulangé, M; Camelot, G; Fontenaille, C, 1969)
"The effect of prolonged preoperative treatment with spironolactone has been studied in a series of 67 patients with hypertension, aldosterone excess, and low plasma renin."7.65Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin. ( Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Haywood, E; Lever, AF; Robertson, JI, 1972)
"The content of aldosterone, corticosterone, and cortisol has been assayed in normal adrenal tissue obtained at autopsy and in adrenal adenomas from both normotensive and hypertensive patients obtained at autopsy and from patients with primary aldosteronism obtained at surgery."7.64The steroid content of adrenal adenomas and measurements of aldosterone production in patients with essential hypertension and primary aldosteronism. ( Kaplan, NM, 1967)
"Aldosterone was not associated with IMMR, insulin sensitivity, or blood pressure and was unaffected by weight loss."6.87Aldosterone Is Not Associated With Metabolic and Microvascular Insulin Sensitivity in Abdominally Obese Men. ( de Leeuw, PW; Houben, AJHM; Joris, PJ; Kusters, YHAM; Mensink, RP; Plat, J; Schalkwijk, CG; Scheijen, JLJM; Schütten, MTJ; Stehouwer, CDA; van de Waarenburg, MPH, 2018)
"Aldosterone excretion was determined by 24 h urine (24h-UAldo) collected at randomization and after 6 months of follow-up."6.84Effects of continuous positive airway pressure treatment on aldosterone excretion in patients with obstructive sleep apnoea and resistant hypertension: a randomized controlled trial. ( Cavalcanti, AH; Cortez, AF; de Souza, F; Margallo, V; Muxfeldt, ES; Salles, GF, 2017)
"Primary aldosteronism (PA) is an endocrine related condition leading to arterial hypertension due to inappropriately high and unregulated aldosterone concentration."6.82Primary Aldosteronism, Aldosterone, and Extracellular Vesicles. ( Carvajal, CA; Fardella, CE; Pérez, JA; Tapia-Castillo, A, 2022)
"Primary aldosteronism (PA) affects millions of individuals worldwide."6.82High Prevalence of Autonomous Aldosterone Production in Hypertension: How to Identify and Treat It. ( Lieberman, L; Turcu, AF; Wannachalee, T, 2022)
"Primary aldosteronism (PA) is the most common and potentially curable form of secondary hypertension, affecting 5-10% of primary care patients with hypertension."6.82Performance of the aldosterone-to-renin ratio as a screening test for primary aldosteronism in primary care. ( Ariens, J; Choy, KW; Horvath, AR; Yang, J, 2022)
"Primary aldosteronism (PA) is the leading cause of secondary hypertension, accounting for over 10% of patients with high blood pressure."6.82Update on the Genetics of Primary Aldosteronism and Aldosterone-Producing Adenomas. ( Faucz, FR; Hannah-Shmouni, F; Pitsava, G; Stratakis, CA, 2022)
"Increased abdominal obesity is associated with increased cardiovascular risk, especially in African American women."6.82Relationship Between Obesity, Hypertension, and Aldosterone Production in Postmenopausal African American Women: A Pilot Study. ( Bakris, GL; Laffin, LJ; Liao, C; Majewski, C, 2016)
"The high prevalence of obstructive sleep apnea in patients with resistant hypertension could be mediated by an activation of the renin-angiotensin-aldosterone system."6.79A randomized controlled study of CPAP effect on plasma aldosterone concentration in patients with resistant hypertension and obstructive sleep apnea. ( Espinel, E; Ferrer, R; Lloberes, P; Martínez-Garcia, MA; Ramon, MA; Romero, O; Sampol, G; Segarra, A; Tovar, JL, 2014)
"Aldosterone breakthrough was observed in 22 of the subjects (55%)."6.78Effect of aldosterone breakthrough on albuminuria during treatment with a direct renin inhibitor and combined effect with a mineralocorticoid receptor antagonist. ( Fukuda, S; Sato, A, 2013)
"Aldosterone production causes vascular injury and may occur despite the long-term administration of angiotensin converting enzyme-inhibitors (ACE-I) (ie, aldosterone breakthrough)."6.74Effects of ARB or ACE-inhibitor administration on plasma levels of aldosterone and adiponectin in hypertension. ( Hoshino, J; Hosoi, T; Iwasaki, T; Kawachi, K; Kurabayashi, M; Morishita, K; Nakamura, T; Ohyama, Y; Saito, T; Saito, Y, 2009)
"Amiloride 40 mg was as effective as the other diuretics."6.73The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio. ( Ashby, MJ; Brown, MJ; Hood, SJ; Taylor, KP, 2007)
"Aldosterone is a mineralocorticoid hormone that controls body fluid and electrolyte balance."6.72Aldosterone, Inflammation, Immune System, and Hypertension. ( Ferreira, NS; Paradis, P; Schiffrin, EL; Tostes, RC, 2021)
"Primary aldosteronism (PA) is one of the most frequent curable forms of secondary hypertension."6.72Functional Characteristic and Significance of Aldosterone-Producing Cell Clusters in Primary Aldosteronism and Age-Related Hypertension. ( Azizan, EA; Pauzi, FA, 2021)
"The ARR threshold to screen for primary aldosteronism may be based on measurement of irR."6.71Active renin versus plasma renin activity to define aldosterone-to-renin ratio for primary aldosteronism. ( Ferrari, P; Nicod, J; Nussberger, J; Saner, E; Shaw, SG, 2004)
"Aldosterone antagonism has BP-independent effects on arterial stiffness."6.71Aldosterone-to-renin ratio, arterial stiffness, and the response to aldosterone antagonism in essential hypertension. ( Feely, J; Mahmud, A, 2005)
"Primary aldosteronism is a specifically treatable and potentially curable form of secondary hypertension."6.70Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism. ( Chiandussi, L; Milan, A; Morello, F; Mulatero, P; Paglieri, C; Rabbia, F; Veglio, F, 2002)
"When amiloride was withdrawn for 2 weeks, there was a large increase in blood pressure of 17/8+/-4/2 mm Hg (systolic, P<0."6.70Amiloride, a specific drug for hypertension in black people with T594M variant? ( Baker, EH; Dong, Y; Duggal, A; Ireson, NJ; MacGregor, GA; Markandu, ND; Wood, M, 2002)
"Losartan appears to be an effective anti-hypertensive agent in patients with mild to moderate hypertension."6.68Effects of losartan on the renin-angiotensin-aldosterone axis in essential hypertension. ( Bauer, IH; Lau-Sieckman, A; Reams, GP; Wu, Z, 1995)
" All patients received three dosing regimens administered in random order: (a) intravenous frusemide: 40 mg bolus then 40 mg h-1 for 3 h, (b) captopril: two 12."6.68The renin angiotensin aldosterone system and frusemide response in congestive heart failure. ( Cerimele, B; Greene, P; Reed, S; Ryan, T; Schwertschlag, U; Voelker, J; Weinberger, M, 1995)
"Neuropeptide Y (NPY) has been recently characterized as a circulating vasoconstrictor peptide which is co-stored with noradrenaline in sympathetic neurons."6.68[Concentration of neuropeptide Y in serum of patients with primary hypertension]. ( Halawa, B; Salomon, P, 1996)
"Essential hypertension is a very common disease in the world."6.68[Selected components of the kallikrein-kinin system and of the renin-angiotensin-aldosterone system in offspring of parents with hypertension]. ( Marzecka, J, 1996)
"Losartan (DuP 753) is a novel orally active angiotensin II antagonist that lowers blood pressure."6.67Hemodynamic and humoral effects of the angiotensin II antagonist losartan in essential hypertension. ( Carroll, J; Grossman, E; Peleg, E; Rosenthal, T; Shamiss, A, 1994)
"Treatment with felodipine ER over 2 weeks increased sympathetic outflow as indicated by elevated plasma norepinephrine levels, whereas plasma epinephrine was mainly unaffected, as were plasma renin and aldosterone levels."6.67Catecholamines and the renin-angiotensin-aldosterone system during treatment with felodipine ER or hydrochlorothiazide in essential hypertension. ( Binner, L; Gabrielsen, F; Hombach, V; Koenig, W; Rosenthal, J; Sund, M, 1991)
"Aldosterone levels were also increased after three months, but without a subsequent decrease."6.67Isradipine in the treatment of hypertension. Some additional effects observed during a one-year study. ( Mayer, O; Polivkova, H; Rottenborn, J, 1991)
"Nicardipine (80 mg/day) was given orally for 12 weeks and no dietary restrictions were imposed."6.67Efficacy of nicardipine slow release (SR) on hypertension, potassium balance and plasma aldosterone in idiopathic aldosteronism. ( Bisbocci, D; Chiandussi, L; Pinna, G; Piras, D; Rabbia, F; Veglio, F, 1990)
"Primary hyperaldosteronism (PA) is a well-known cause of hypertension although its exact prevalence amongst patients with apparent essential hypertension has been a matter of debate."6.66Five Reasons for the Failure to Diagnose Aldosterone Excess in Hypertension. ( Chrousos, GP; Kaltsas, G; Markou, A; Piaditis, GP, 2020)
"Bopindolol is a new long-acting, nonselective beta-adrenoceptor antagonist with partial agonist activity."6.66The clinical pharmacology of bopindolol, a new long-acting beta-adrenoceptor antagonist, in hypertension. ( Boomsma, F; Derkx, FH; Man in 't Veld, AJ; Mulder, P; Schalekamp, MA; van den Meiracker, AH; van Eck, HJ, 1987)
"Celiprolol is a newly developed cardioselective beta-blocking agent with mild beta 2-agonist and weak alpha 2-antagonist properties."6.66Effects of celiprolol on plasma renin, aldosterone, norepinephrine and epinephrine in primary hypertension. ( DeQuattro, V; Hernandez, PH; Kimura, S; Lee, DD, 1988)
" Further measurements were made during a series of intensive study days, and the most important additional finding was a pharmacokinetic interaction that resulted in increased peak concentrations and bioavailability of prazosin."6.66The combination of prazosin and verapamil in the treatment of essential hypertension. ( Campbell, L; Elliott, HL; Meredith, PA; Reid, JL, 1988)
"Nicardipine appears to blunt the secretion of aldosterone responding to an increased PRA possibly through its calcium-antagonizing action."6.66Multiple oral doses of nicardipine, a calcium-entry blocker: effects on renal function, plasma renin activity, and aldosterone concentration in mild-to-moderate essential hypertension. ( Aoyagi, K; Baba, T; Ishizaki, T; Murabayashi, S; Takebe, K; Tamasawa, N, 1987)
"Guanfacine monotherapy was again shown to be an effective initial treatment for mild essential hypertension with no adverse influence on serum lipids."6.66Guanfacine as monotherapy for systemic hypertension. ( Blackshear, JL; Fillingim, JM; Strauss, A; Strauss, M, 1986)
"Captopril was administered orally in 2 daily doses of 25 to 200 mg."6.65Uncontrollable hypertension in patients on hemodialysis: long-term treatment with captopril and salt subtraction. ( Brunner, HR; Gavras, H; Guignard, JP; Turini, GA; Waeber, B; Wauters, JP, 1981)
"In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)."6.65[Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984)
"Labetalol was more effective in lowering blood pressure but less effective in reducing pulse rate of plasma angiotensin II concentration."6.64Effect of blood pressure angiotensin II and aldosterone concentrations during treatment of severe hypertension with intravenous labetalol: comparison with propranolol. ( Brown, JJ; Fraser, R; Lever, AF; Morton, JJ; Robertson, JI; Rosei, EA; Trust, PM, 1976)
"Treatment with propranolol resulted in marked suppression of the plasma renin activity (1."6.64Intrapatient comparison of treatment with chlorthalidone, spironolactone and propranolol in normoreninemic essential hypertension. ( Benraad, TJ; Drayer, JI; Festen, J; Kloppenborg, PW; van't Laar, A, 1975)
"Primary aldosteronism (PA) is the most prevalent cause of secondary hypertension (3%-32% of hypertensive patients)."6.61The aldosterone to renin ratio in the diagnosis of primary aldosteronism: Promises and challenges. ( Denieffe, S; Fitzgibbon, MC; Griffin, TP; O'Shea, PM, 2019)
"Primary aldosteronism is the most common form of secondary hypertension."6.58Overview of aldosterone-related genetic syndromes and recent advances. ( Boulkroun, S; Fernandes-Rosa, FL; Zennaro, MC, 2018)
"Obese subjects often exhibit hyperaldosteronism, with increased salt sensitivity of blood pressure (BP)."6.53The Role of Aldosterone in Obesity-Related Hypertension. ( Fujita, T; Kawarazaki, W, 2016)
"Obesity is a serious health hazard with rapidly increasing prevalence in the United States."6.53Obesity, hypertension and aldosterone: is leptin the link? ( Bollag, WB; Xie, D, 2016)
"Obesity is a multifactorial disease associated with hypertension."6.52Reviving the use of aldosterone inhibitors in treating hypertension in obesity. ( Belin De Chantemèle, EJ; Huby, AC, 2015)
"Obesity is epidemic and is associated with increased blood pressure, which often manifests as treatment-resistant hypertension."6.50A critical review of the evidence supporting aldosterone in the etiology and its blockade in the treatment of obesity-associated hypertension. ( Brook, RD; Byrd, JB, 2014)
"Other than treatment for weight loss, treatment of hypertension with specific antihypertensive medications that block or reduce aldosterone action are appropriate in obese patients."6.50Increased aldosterone: mechanism of hypertension in obesity. ( Flynn, C, 2014)
"Resistant hypertension is a clinically distinct subgroup of hypertension defined by the failure to achieve blood pressure control on optimal dosing of at least 3 antihypertensive medications of different classes, including a diuretic."6.50Pathophysiology and treatment of resistant hypertension: the role of aldosterone and amiloride-sensitive sodium channels. ( Calhoun, DA; Judd, EK; Warnock, DG, 2014)
"Hypertension is traditionally considered a disease in which elevated blood pressure contributes to inflammation and activation of the immune system, leading to cardiovascular injury and end-organ damage."6.49Immune system alterations by aldosterone during hypertension: from clinical observations to genomic and non-genomic mechanisms leading to vascular damage. ( Barake, MF; Campino, C; Fardella, CE; Kalergis, AM; Letelier, NA; Muñoz-Durango, N, 2013)
"Hypertension is an established risk factor for stroke, premature coronary artery disease and heart failure."6.49Aldosterone synthase inhibition in hypertension. ( Andersen, K, 2013)
"A close association exists between hyperaldosteronism, RHTN, and obstructive sleep apnea (OSA) based upon recent studies which indicate that OSA is worsened by aldosterone-mediated fluid retention."6.48Resistant hypertension and aldosterone: an update. ( Ahmed, MI; Calhoun, DA; Clark, D, 2012)
" The observation of reduced nitric oxide bioavailability in hyperaldosteronism implied the generation of oxidative stress by aldosterone."6.48Aldosterone, oxidative stress, and NF-κB activation in hypertension-related cardiovascular and renal diseases. ( Queisser, N; Schupp, N, 2012)
"In the setting of primary aldosteronism, elevated aldosterone levels are associated with increased blood pressure."6.46Aldosterone and arterial hypertension. ( Obermayer-Pietsch, B; Pieber, TR; Pilz, S; Ritz, E; Tomaschitz, A, 2010)
"Aldosterone was in the past considered only as a prohypertensinogenic agent."6.46Aldosterone in uremia - beyond blood pressure. ( Koleganova, N; Ritz, E, 2010)
"Eplerenone has been reported to have anti-hypertensive and protective effects on cardiovascular and renal injury in salt-sensitive hypertensive animal models, such as the Dahl salt-sensitive (DS) hypertensive rat and leptin receptor-deficient spontaneously hypertensive rat (SHR/cp)."6.45Effects of eplerenone, a selective mineralocorticoid receptor antagonist, on clinical and experimental salt-sensitive hypertension. ( Takeda, Y, 2009)
"Features of visceral obesity and obstructive sleep apnea that may stimulate aldosterone secretion are described here."6.44Obesity, sleep apnea, aldosterone, and hypertension. ( Goodfriend, TL, 2008)
"Aldosterone has also been shown to exert a number of effects in the central nervous system."6.44Aldosterone and the vasculature: mechanisms mediating resistant hypertension. ( Duprez, DA, 2007)
"Aldosterone is an important mediator in the pathogenesis of heart failure, and increased plasma aldosterone levels are associated with a poor prognosis."6.44Drug insight: aldosterone-receptor antagonists in heart failure--the journey continues. ( Francis, GS; Kalidindi, SR; Tang, WH, 2007)
"Overweight and obesity are associated with arterial hypertension."6.44The association of aldosterone with obesity-related hypertension and the metabolic syndrome. ( Bochud, M; Burnier, M; Vogt, B, 2007)
"The syndrome of primary aldosteronism, however, encompasses a wide spectrum of disorders that will require better definition."6.44Aldosterone and refractory hypertension. ( Nyirenda, MJ; Padfield, PL, 2007)
"Metabolic syndrome is an aggregation of hypertension, diabetes and dyslipidaemia."6.44Aldosterone in salt-sensitive hypertension and metabolic syndrome. ( Fujita, T, 2008)
"Aldosterone plays an important role in the pathogenesis of cardiovascular disease."6.43Role of cardiovascular aldosterone in hypertension. ( Takeda, Y, 2005)
"Aldosterone is an important and independent target for therapeutic intervention in hypertension and hypertension-related diseases."6.42Aldosterone receptor antagonists for hypertension: what do they offer? ( Krum, H; Liew, D, 2003)
"The classical form of primary aldosteronism is a rare disease with prevalence rates of 0."6.42[The aldosterone to Renin ratio in secondary hypertension]. ( Reincke, M; Seiler, L, 2003)
"Aldosterone has been only considered as a humoral factor playing a role in salt and water homeostasis and as a consequence controlling arterial blood pressure."6.41[Aldosterone and cardiovascular diseases, more than water and salt retention]. ( Duprez, D, 2002)
"Aldosterone has been identified as a critically important neurohormone with direct detrimental effects on the myocardium."6.41Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure. ( Miller, AB; Srivastava, P, 2001)
"Among these, classic primary hyperaldosteronism and its glucocorticoid remediable variety, in which hypertension is secondary to aldosterone production, must be considered."6.40[Hypertension and mineralocorticoids. Usefulness of renin and aldosterone measurements]. ( Fardella, CE; Montero, J; Mosso, L, 1999)
"According to the primary aldosteronism surgical outcome (PASO) criteria, complete and partial clinical success was achieved in 21 (40."5.91Catheter-based adrenal ablation: an alternative therapy for patients with aldosterone-producing adenoma. ( He, H; Jiang, J; Li, Q; Li, Y; Liu, X; Sun, F; Yan, Z; Zhang, H; Zhao, Z; Zhou, X; Zhu, Z, 2023)
"Primary aldosteronism (PA) screening relies on an elevated aldosterone to renin ratio with a minimum aldosterone level, which varies from 10 to 15 ng/dL (277-415."5.91Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening. ( Almeida, MQ; Bortolotto, LA; Brito, LP; Carnevale, FC; Cavalcante, ACBS; Chambo, JL; Coelho, FMA; Consolim-Colombo, FM; Drager, LF; Fagundes, GFC; Fragoso, MCBV; Freitas, TC; Goldbaum, TS; Latronico, AC; Ledesma, FL; Maciel, AAW; Mendonca, BB; Pereira, MAA; Petenuci, J; Pilan, B; Pio-Abreu, A; Silveira, JV; Srougi, V; Tanno, FY; Vilela, LAP; Zerbini, MCN, 2023)
"After genetic analysis, a diagnosis of Liddle syndrome was made due to the presence of a p."5.91A case report of a young boy with low renin and high aldosterone levels induced by Liddle syndrome who was previously misdiagnosed with primary aldosteronism. ( Jin, Y; Qiu, W; Yao, J, 2023)
"Aldosterone has hypertrophic and profibrotic effects on the heart."5.91Serum aldosterone effect on left ventricular structure and diastolic function in essential hypertension. ( Al-Hashedi, EM; Juvenal, H; Mohammed, AA; Yu, J; Zhao, X, 2023)
"Primary aldosteronism (PA) was suspected because of the high plasma aldosterone concentration-to-plasma renin activity ratio."5.91Coexistence of Pheochromocytoma and Primary Aldosteronism due to Multiple Aldosterone-producing Micronodules in the Ipsilateral Adrenal Gland. ( Fujita, Y; Hino, M; Horikawa, O; Inoue, K; Kageyama, S; Kawauchi, A; Maegawa, H; Nakaizumi, N; Noujima, M; Sasano, H; Sato, D; Ugi, S; Wada, A; Yamazaki, Y; Yonishi, M, 2023)
"Primary aldosteronism is the most frequent secondary hypertensive disease and is characterized by an elevated risk for cardiovascular disease."5.91Effect of the interaction between the visceral-to-subcutaneous fat ratio and aldosterone on cardiac function in patients with primary aldosteronism. ( Fujiwara, A; Haruna, A; Haze, T; Hirawa, N; Kawano, R; Kobayashi, Y; Ohki, Y; Ozawa, M; Saka, S; Suzuki, S; Tamura, K, 2023)
"Primary aldosteronism (PA) is considered the number one aetiology for secondary hypertension."5.91Duplicated adrenal veins in primary aldosteronism misdiagnosed with ectopic aldosteronoma due to apparent bilateral aldosterone suppression. ( Chen, K; Fan, C; Fang, T; Liu, H; Quan, H; Wei, W; Yu, J; Zhang, Y, 2023)
"Patients with primary aldosteronism (PA) have a higher risk of cardiovascular disease (CVD) than essential hypertension due to underlying hyperaldosteronism."5.91High plasma aldosterone concentration is associated with worse 24-h ambulatory blood pressure profile in patients with primary aldosteronism. ( Azushima, K; Haze, T; Kanaoka, T; Kinguchi, S; Kobayashi, K; Kobayashi, R; Morita, R; Sunohara, S; Tamura, K; Toya, Y; Wakui, H, 2023)
"Primary aldosteronism was diagnosed based on 4 h PAC, adrenal imaging and/or adrenal venous sampling (AVS)."5.91Using plasma aldosterone concentrations at 1 h of saline infusion test for the diagnosis of primary aldosteronism. ( Chanthanuwat, S; Jannoo, S; Phonanuwong, R; Soonthornpun, S, 2023)
"Primary aldosteronism (PA) is a well-known cause of secondary hypertension."5.91Simple standing test without furosemide is useful in the diagnosis of primary aldosteronism. ( Fushimi, Y; Iwamoto, H; Iwamoto, Y; Kaku, K; Kaneto, H; Katakura, Y; Kimura, T; Kusano, T; Mune, T; Nakanishi, S; Ohnishi, M; Sanada, J; Shimoda, M; Takenouchi, H; Tatsumi, F, 2023)
"Atypical Liddle syndrome can be easily misdiagnosed due to its clinical phenotypes resembling hyperaldosteronism."5.91Liddle syndrome presenting with normal aldosterone levels: A case report. ( Pan, R; Wang, R; Zhang, R; Zhang, Y; Zhao, Y, 2023)
"In 2017, the Primary Aldosteronism Surgical Outcome (PASO) investigators proposed consensus criteria for clinical and biochemical outcomes."5.72Prediction of long-term biochemical cure in patients with unilateral primary hyperaldosteronism treated surgically based on the early post-operative plasma aldosterone value. ( Ishihara, Y; Kaneko, H; Kusakabe, T; Nanba, K; Satoh-Asahara, N; Tagami, T; Tsuiki, M; Umakoshi, H; Yasoda, A, 2022)
" The results of restricted cubic splines showed the dose-response association between increasing PAC, ARR, decreasing serum potassium, and the risk of WMLs."5.72Plasma aldosterone concentration is associated with white matter lesions in patients with primary aldosteronism. ( Heizhati, M; Li, N; Liu, Y; Luo, Q; Wang, M; Yao, X; Yuan, Y; Zhu, Q, 2022)
"We identified patients with aortic dissection and aneurysm with assessed PAC before disease onset from hospital-based electronic database and set as case group."5.72Higher Plasma Aldosterone Concentrations Are Associated With Elevated Risk of Aortic Dissection and Aneurysm: a Case-Control Study. ( Gan, L; Heizhati, M; Hong, J; Li, N; Lin, M; Luo, Q; Wang, M; Yao, X; Yue, N; Zhang, W; Zhu, Q, 2022)
"Diagnosis of primary hyperaldosteronism in pregnancy is complicated due to lack of reference ranges for aldosterone, renin and aldosterone-to-renin ratio."5.72Establishing Reference Ranges for Aldosterone, Renin and Aldosterone-to-Renin Ratio for Women in the Third-Trimester of Pregnancy. ( Grzesiak, M; Horzelski, W; Lewandowski, KC; Lewinski, A; Tadros-Zins, M, 2022)
"Among 43 patients with primary aldosteronism (PA), thirteen APA patients were enrolled in this study."5.72Early Renin Recovery After Adrenalectomy in Aldosterone-Producing Adenomas: A Prospective Study. ( Antonini, SR; de Castro, M; Elias, J; Elias, PCL; Mermejo, LM; Molina, CAF; Moreira, AC; Muglia, VF; Tucci, S, 2022)
"Among those Liddle syndrome patients confirmed by a genetic test, for Test kit A all ARR were screened positive while for test kit B negative."5.72Liddle syndrome misdiagnosed as primary aldosteronism is caused by inaccurate aldosterone-rennin detection while a novel ( Chen, L; Qu, D; Sun, Q; Wu, C; Xu, X; Yang, Y; Zhao, X, 2022)
"Ambulatory FST is safe and accurate and can be performed with significantly less healthcare costs compared to FSTin."5.72Ambulatory fludrocortisone suppression test in the diagnosis of primary aldosteronism: Safety, accuracy and cost-effectiveness. ( Avander, K; Calissendorff, J; Carasel, A; Falhammar, H; Shabo, I; Volpe, C, 2022)
"Racial differences in obstructive sleep apnea (OSA) and increased aldosterone level may explain the racial disparity in resistant hypertension prevalence."5.72Relationship Between Risks for Obstructive Sleep Apnea, Resistant Hypertension, and Aldosterone Among African American Adults in the Jackson Heart Study. ( Eaton, CB; Gjelsvik, A; Hall, ME; Koo, P; McCool, FD; Muntner, P, 2022)
"Primary aldosteronism (PA), including aldosterone and cortisol producing adenoma (A/CPA), is the most common trigger of secondary hypertension."5.72Two cases of aldosterone and cortisol producing adenoma with different histopathological features: A case report. ( Gao, H; Li, L; Tian, H, 2022)
"Hypertension is a major health problem common in the elderly people."5.72Green tea could improve elderly hypertension by modulating arterial stiffness, the activity of the renin/angiotensin/aldosterone axis, and the sodium-potassium pumps in old male rats. ( Akbari, A; Gao, J; Wang, T, 2022)
"Preeclampsia is a life-threatening disorder of pregnancy unique to humans."5.72Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia. ( Dimitriadis, E; Menkhorst, E; Santos, L; St-Pierre, Y; Young, MJ; Zhang, JG; Zhou, W, 2022)
"Primary aldosteronism, eponymously known as Conn's syndrome, has recently gained recognition as the most common cause of endocrine hypertension."5.62The role of surgery in Conn's syndrome - a case of refractory hypertension secondary to an aldosterone secreting adenoma. ( Bombil, I; Carides, MD; Christofides, C; Sishuba, NT, 2021)
"Primary aldosteronism was diagnosed."5.62Hypertension with unilateral adrenal aldosterone and cortisol cosecreting adenoma: A case report. ( Chen, X; Chu, SL; Hu, Z; Luo, FX; Shao, Y; Wang, JG, 2021)
"Primary aldosteronism is an underdiagnosed cause of hypertension."5.62Intraindividual Variability of Aldosterone Concentrations in Primary Aldosteronism: Implications for Case Detection. ( Fudim, T; Hundemer, GL; Moussa, M; Sacks, B; Underhill, J; Vaidya, A; Yozamp, N, 2021)
"Allisartan isoproxil (ALL) is a new angiotensin II receptor blocker and a new antihypertensive drug discovered and developed in China."5.62Allisartan isoproxil reduces mortality of stroke-prone rats and protects against cerebrovascular, cardiac, and aortic damage. ( Cheng, MH; Fu, FH; Ling, QS; Liu, AJ; Liu, JG; Miao, CY; Tian, JS; Zhang, SL, 2021)
"Primary aldosteronism (PA) is highly prevalent in hypertensive population."5.62Determination of adrenal hypersecretion in primary Aldosteronism without aldosterone-production adenomas. ( He, H; Hong, Y; Liu, X; Sun, F; Yan, Z; Zhang, H; Zhao, Z; Zhu, Z, 2021)
"Residual hypertension was defined as persistent hypertension > 140/90 mmHg or requiring anti-hypertensive medications 1 year after surgery."5.62Comparison of cystatin C-based and creatinine-based glomerular filtration rate in the prediction of postoperative residual hypertension in aldosterone-producing adenoma patients after adrenalectomy. ( Chang, CC; Chen, CW; Chiu, YW; Hung, CS; Liao, SC; Lin, YH; Liu, KL; Tsai, CH; Tsai, IJ; Wu, VC, 2021)
"Essential hypertension is a pivotal risk factor for the development of cardiovascular disease (CVD)."5.62Aldosterone hyperreactivity to acute psychosocial stress induction in men with essential hypertension. ( Ehlert, U; Gideon, A; Sauter, C; von Känel, R; Wirtz, PH, 2021)
"Primary aldosteronism (PA), as a cause of secondary hypertension, can cause more serious cardiovascular damage than essential hypertension."5.62A case of primary aldosteronism with a negative aldosterone-to-renin ratio. ( Ding, Y; Liu, F; Wang, L, 2021)
"Aldosterone has been linked with obesity, metabolic syndrome (MetS), pro-inflammatory, and prothrombotic states; however, most studies relate these indicators with primary aldosteronism (PA), excluding non-PA patients."5.51The Aldosterone/Renin Ratio Predicts Cardiometabolic Disorders in Subjects Without Classic Primary Aldosteronism. ( Allende, F; Barros, ER; Baudrand, R; Campino, C; Carvajal, C; Fardella, CE; Fuentes, CA; García, H; Kalergis, AM; Martínez-Aguayo, A; Olmos, R; Solari, S; Tapia-Castillo, A; Vecchiola, A, 2019)
"The aldosterone-treated mice were exposed to NaCl drinking water (1%) during the hormone administration."5.48Disruption of the with no lysine kinase-STE20-proline alanine-rich kinase pathway reduces the hypertension induced by angiotensin II. ( Alessi, DR; Bobadilla, NA; Castaneda-Bueno, M; Cervantes-Perez, LG; Gamba, G; Jimenez, JV; Rojas-Vega, L; Vazquez, N, 2018)
"In patients with KCNJ5-mutated APA, left ventricular hypertrophy was significantly decreased by surgical treatment in patients from either Cured or Improved groups, although those patients with wild-type KCNJ5 showed no change."5.48KCNJ5 mutation as a predictor for resolution of hypertension after surgical treatment of aldosterone-producing adenoma. ( Kitamoto, T; Nishikawa, T; Omura, M; Saito, J; Suematsu, S, 2018)
"Current threshold values for primary aldosteronism (PA) diagnostic testing are based on measuring aldosterone (PAC) using immunoassays."5.48Aldosterone LC-MS/MS Assay-Specific Threshold Values in Screening and Confirmatory Testing for Primary Aldosteronism. ( Ahmed, AH; Gordon, RD; Guo, Z; McWhinney, BC; Poglitsch, M; Stowasser, M; Ungerer, JPJ; Wolley, M, 2018)
"Consecutive patients with diagnosed primary hyperaldosteronism from June 2006 to July 2012 in our center underwent adrenal surgeries without pre-operational adrenal venous sampling (AVS) if all the three criteria were met: (1) round- or oval-shaped occupational lesion of low density after contrast enhancement with diameter >1 cm on CT scan was located in one adrenal gland; (2) unequivocally normal contralateral adrenal gland; (3) serum potassium level lower than 3."5.46Favorable surgical outcomes of aldosterone-producing adenoma based on lateralization by CT imaging and hypokalemia: a non-AVS-based strategy. ( Cao, X; Feng, X; Li, H; Li, Y; Liu, J; Liu, L; Wei, G, 2017)
"We described the prevalence of primary aldosteronism in our population before the change and, using the assumption of disease prevalence stability, determined the corresponding ratio cutoffs after the introduction of the new assay."5.46Novel Approach to Establishing an Aldosterone: Renin Ratio Cutoff for Primary Aldosteronism. ( Chin, A; Kline, GA; Leung, AA; Orton, DJ; Sadrzadeh, H, 2017)
"All primary aldosteronism patients were diagnosed by autonomous aldosterone secretion using confirmatory tests, and then divided into nPA (n = 130) and primary aldosteronism patients with high PAC (hPA: n = 162) using a PAC cutoff level of less than 443 pmol/l (16 ng/dl), representing the normal upper limit of PAC."5.46Plasma aldosterone level within the normal range is less associated with cardiovascular and cerebrovascular risk in primary aldosteronism. ( Hamasaki, T; Hashimoto, K; Hayashi, RD; Kajimoto, Y; Kitamura, T; Kouhara, H; Kurebayashi, S; Mukai, K; Murata, M; Nakao, M; Otsuki, M; Shimomura, I; Takeiri, S; Tamada, D; Yamamoto, T, 2017)
"Eplerenone treatment of patients with PA reduces blood pressure, increases serum potassium level, and improves vascular status."5.43Eplerenone improves carotid intima-media thickness (IMT) in patients with primary aldosteronism. ( Anzai, K; Kawate, H; Matsuda, Y; Matsuzaki, C; Nomura, M; Ohnaka, K; Sakamoto, R; Shibue, K; Takayanagi, R, 2016)
"Primary aldosteronism is one of the most common forms of secondary hypertension, but it is often under diagnosed, which leads to the development of cardiovascular damage, and excess costs for long-term drug treatment and management of complications."5.43The Aldosterone Renin Ratio (ARR) APP as Tool to Enhance the Detection Rate of Primary Aldosteronism. ( Bisogni, V; Rossi, GP, 2016)
"Our data indicate that in mice with Liddle syndrome, the primary site of increased Na(+) reabsorption is the DCT2/CNT."5.43In Liddle Syndrome, Epithelial Sodium Channel Is Hyperactive Mainly in the Early Part of the Aldosterone-Sensitive Distal Nephron. ( Bertog, M; Dahlmann, A; Korbmacher, C; Krueger, B; Nesterov, V; Palmisano, R, 2016)
"Hypertension was resolved less frequently after treatment with RFA compared with laparoscopic adrenalectomy (13 of 36 versus 19 of 27 patients; P = 0·007)."5.43Radiofrequency ablation compared with laparoscopic adrenalectomy for aldosterone-producing adenoma. ( Chiu, PW; Chow, FC; Chu, CM; Kong, AP; Liu, SY; Ng, EK; Wong, SK, 2016)
"Prospective studies indicate that hyperaldosteronism is found in 20% of patients with resistant hypertension."5.43Body Mass Index Predicts 24-Hour Urinary Aldosterone Levels in Patients With Resistant Hypertension. ( Calhoun, DA; Dudenbostel, T; Ghazi, L; Li, P; Liu, M; Oparil, S, 2016)
"Primary aldosteronism (PA), the most common form of secondary hypertension, causes relevant morbidity."5.43The Clinical Value of Salivary Aldosterone in Diagnosis and Follow-Up of Primary Aldosteronism. ( Asbach, E; Bidlingmaier, M; Fourkiotis, V; Gerum, S; Lichtenauer, UD; Manolopoulou, J; Quinkler, M; Reincke, M, 2016)
"The diagnosis of primary aldosteronism (PA) among the older-aged population has posed a crucial challenge."5.42The value of losartan suppression test in the confirmatory diagnosis of primary aldosteronism in patients over 50 years old. ( Balakrishnan, P; Chen, YM; Chueh, SC; Hsein, YC; Kuo, CC; Wang, MJ; Wu, KD; Wu, VC, 2015)
"Aldosterone has hypertrophic and profibrotic effects on the heart."5.42Plasma aldosterone and left ventricular diastolic function in treatment-naïve patients with hypertension: tissue-Doppler imaging study. ( Catena, C; Kraigher-Krainer, E; Pieske, B; Pilz, S; Sechi, LA; Tomaschitz, A; Verheyen, N, 2015)
"Prehypertension has been associated with adverse cerebrovascular events and brain damage."5.40Long-term prehypertension treatment with losartan effectively prevents brain damage and stroke in stroke-prone spontaneously hypertensive rats. ( He, DH; Lin, JX; Lin, LM; Ning, RB; Wang, HJ; Xu, CS; Zhang, LM, 2014)
"Aldosterone was associated with higher SBP only in Hispanics (2."5.40Association of renin and aldosterone with ethnicity and blood pressure: the Multi-Ethnic Study of Atherosclerosis. ( Allison, MA; Budoff, M; Ix, JH; Jenny, NS; Khaki, AR; McClelland, RL; Rifkin, DE; Watson, K, 2014)
"In 10 patients with primary aldosteronism, median supine ARRP was 298 (range 48-1222) and ARRD 34 (range 2."5.40Measurement of plasma renin concentration instead of plasma renin activity decreases the positive aldosterone-to-renin ratio tests in treated patients with essential hypertension. ( Bassani, N; Biganzoli, E; Gritti, A; Lonati, C; Morganti, A, 2014)
"A correct diagnosis of primary aldosteronism (PA) requires adrenal venous sampling (AVS) for the classification of subtypes (bilateral hyperplasia, BAH, or adenoma, APA)."5.40Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma. ( Brazzarola, P; Castagna, A; Cecconi, D; Chiecchi, L; D'Alessandro, A; Guarini, P; Gunasekaran, M; Morandini, F; Mulatero, P; Olivieri, O; Pizzolo, F; Veglio, F; Zolla, L, 2014)
"When hexamethonium was used to assess autonomic control of MAP, no differences in the decrease of MAP in response to ganglionic blockade were detected during the induction."5.40CNS neuroplasticity and salt-sensitive hypertension induced by prior treatment with subpressor doses of ANG II or aldosterone. ( Beltz, T; Clayton, SC; Johnson, AK; Xue, B; Zhang, Z, 2014)
"Aldosterone-salt treatment induces not only hypertension but also extensive inflammation that contributes to fibrosis in the rat kidney."5.40Mizoribine ameliorates renal injury and hypertension along with the attenuation of renal caspase-1 expression in aldosterone-salt-treated rats. ( Doi, S; Doi, T; Kohno, N; Masaki, T; Nakashima, A; Ueno, T; Yokoyama, Y, 2014)
"Aldosterone excess has a direct negative effect on β-cell function in patients with PA."5.39Aldosterone excess impairs first phase insulin secretion in primary aldosteronism. ( Adolf, C; Beuschlein, F; Bidlingmaier, M; Fischer, E; Pallauf, A; Reincke, M; Seissler, J; Then, C, 2013)
"Hyperkalemia is a potentially serious complication following adrenalectomy of aldosterone-producing adenomas (APA)."5.39Incidence and factors of post-adrenalectomy hyperkalemia in patients with aldosterone producing adenoma. ( Cheng, CJ; Chiang, WF; Lin, MY; Lin, SH; Sun, GH; Sung, CC; Wu, ST, 2013)
"Aldosterone values were adjusted statistically for age, sex, and the urinary sodium/creatinine ratio."5.39Bimodal aldosterone distribution in low-renin hypertension. ( Adlin, EV; Braitman, LE; Vasan, RS, 2013)
"Treatment with aldosterone did not alter mitochondrial respiratory function but accelerated Ca(2+)-induced MPT in SSM, but not IFM, compared with healthy old and young beagles."5.39Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs: effects of aging and long-term aldosterone infusion. ( Asemu, G; Cox, JW; Dabkowski, ER; Hecker, PA; Hoppel, CL; O'Connell, KA; Rastogi, S; Ribeiro, RF; Sabbah, HN; Shekar, KC; Stanley, WC; Xu, W, 2013)
"Aldosterone (Aldo) is an important active hormone in the renin-angiotensin-aldosterone system and plays a vital role in the development of hypertension, heart failure and other cardiovascular diseases."5.38Endogenous aldosterone is involved in vascular calcification in rat. ( Cai, Y; Jia, LX; Qi, YF; Tang, CS; Wang, X; Wu, SY; Xiao, CS; Yu, YR, 2012)
"Moreover, aldosterone-producing adrenocortical carcinomas without hypertension are exceedingly rare, with only two previously reported cases."5.38Aldosterone-producing adrenocortical carcinoma without hypertension. ( Bae, SB; Kim, SJ; Kim, YJ; Seo, SW; Song, MS, 2012)
"Primary aldosteronism caused by an aldosterone producing adrenal tumor/aldosteronoma (APA), is a potentially curable form of hypertension, via unilateral adrenalectomy."5.38Persistent hypertension after adrenalectomy for an aldosterone-producing adenoma: weight as a critical prognostic factor for aldosterone's lasting effect on the cardiac and vascular systems. ( Carter, Y; Chen, H; Roy, M; Sippel, RS, 2012)
"1."5.37Association of the aldosterone synthase gene -344T>C polymorphism with essential hypertension and glucose homeostasis: a case-control study in a Han Chinese population. ( Chen, HY; Gao, X; Li, XM; Ling, Y; Liu, Y; Lu, DR; Lu, ZQ; Yi, QL, 2011)
"Primary aldosteronism (PA) is associated with a higher incidence of cardiovascular events, probably through mineralocorticoid receptor (MR)-dependent endothelial cell dysfunction, in comparison with essential hypertension (EH)."5.37Endothelial progenitor cells in primary aldosteronism: a biomarker of severity for aldosterone vasculopathy and prognosis. ( Chen, JW; Chen, YL; Huang, PH; Kuo, CC; Kuo, YS; Lee, BC; Liang, CJ; Lin, SJ; Lin, SL; Lin, YH; Lo, SC; Sun, YY; Tsai, CT; Wu, EL; Wu, KD; Wu, VC, 2011)
"Resistant hypertension has evolved as an important global health care problem."5.37What is the role of aldosterone excess in resistant hypertension and how should it be investigated and treated? ( Sica, DA, 2011)
"Aldosterone plays a role in hypertension, and hypertension is prevalent in patients with insulin resistance."5.37Plasma aldosterone levels and development of insulin resistance: prospective study in a general population. ( Adachi, H; Enomoto, M; Esaki, E; Fukami, A; Hirai, Y; Imaizumi, T; Jacobs, DR; Kasahara, A; Kumagae, S; Kumagai, E; Nanjo, Y; Ogata, K; Ohbu-Murayama, K; Otsuka, M; Tsukagawa, E; Yokoi, K; Yoshikawa, K, 2011)
"Primary aldosteronism (PA) is a possible cause of endocrine hypertension."5.37[Aldosterone/renin ratio in the diagnosis of primary aldosteronism]. ( Catay, E; Honnorat, E; Izquierdo, A; Popescu, BM; Ríos, MC; Rodríguez Cuimbra, S; Sotelo, M, 2011)
"Hypertension was induced in Cyp1a1-Ren-2 rats through dietary administration of the natural xenobiotic indole-3-carbinol (0."5.36Inappropriately high circulating and intrarenal angiotensin II levels during dietary salt loading exacerbate hypertension in Cyp1a1-Ren-2 transgenic rats. ( Bürgelová, M; Cervenka, L; Erbanová, M; Husková, Z; Kramer, HJ; Mullins, JJ; Opocenský, M; Thumová, M; Vanourková, Z, 2010)
"Aldosterone is a prerequisite for this action."5.36Pathogenesis of hypertension: interactions among sodium, potassium, and aldosterone. ( Büssemaker, E; Hausberg, M; Hillebrand, U; Oberleithner, H; Pavenstädt, H, 2010)
"Felodipine has a protective effect on the myocardium and kidney as evidenced by decreased perivascular inflammation, myocardial necrosis and fibrosis."5.36Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats. ( Franco, M; Janicki, JS; Matsubara, BB; Matsubara, LS, 2010)
"Primary aldosteronism (PA) is a frequent cause of secondary hypertension and is amenable to surgical intervention when it is caused by aldosterone-producing adenoma (APA)."5.36Predictors of resolution of hypertension after adrenalectomy in patients with aldosterone-producing adenoma. ( Kim, RM; Lee, J; Soh, EY, 2010)
"Aldosterone and LVH were investigated in 240 and 110 subjects respectively."5.36Association of HSD3B1 and HSD3B2 gene polymorphisms with essential hypertension, aldosterone level, and left ventricular structure. ( Aoi, N; Izumi, Y; Matsumoto, K; Nakayama, T; Sato, M; Sato, N; Shimodaira, M; Soma, M, 2010)
"Hyperaldosteronism (PRA < 1 ng x mL(-1) x h(-1) and UAldo > or = 12 microg/24-h) prevalence was 28% and OSA prevalence was 77%."5.36Severity of obstructive sleep apnea is related to aldosterone status in subjects with resistant hypertension. ( Ahmed, MI; Calhoun, DA; Cofield, SS; Gaddam, KK; Gonzaga, CC; Harding, SM; Oparil, S; Pimenta, E; Thomas, SJ, 2010)
"Resistant hypertension is a common clinical problem and greatly increases the risk of target organ damage."5.35Characterization of resistant hypertension: association between resistant hypertension, aldosterone, and persistent intravascular volume expansion. ( Aban, I; Calhoun, DA; Gaddam, KK; Nishizaka, MK; Oparil, S; Pimenta, E; Pratt-Ubunama, MN, 2008)
"A clear reduction of BP values was recorded after both the first and the second month of treatment with kanrenoate, with the maximal effect obtained when the dosage titration at 100 mg/day was accomplished."5.35Menopause not aldosterone-to-renin ratio predicts blood pressure response to a mineralocorticoid receptor antagonist in primary care hypertensive patients. ( Blengio, GS; Ciacciarelli, A; Corrocher, R; Falcone, S; Olivieri, O; Pizzolo, F; Signorelli, D, 2008)
"Weight loss is associated with reduction of blood pressure and of PRA and aldosterone levels in obese hypertensive subjects."5.35Effect of weight loss through laparoscopic gastric banding on blood pressure, plasma renin activity and aldosterone levels in morbid obesity. ( Dall'Asta, C; Folli, F; Manunta, P; Marchi, M; Paganelli, M; Pizzocri, P; Pontiroli, AE; Vedani, P, 2009)
"Considering the role of aldosterone in diabetic nephropathy, genetic polymorphism of this gene may contribute to the development and progression of diabetic nephropathy."5.35Polymorphism of the aldosterone synthase gene is not associated with progression of diabetic nephropathy, but associated with hypertension in type 2 diabetic patients. ( Cha, DR; Kang, YS; Kim, HK; Ko, GJ; Lee, MH; Song, HK, 2008)
"Primary aldosteronism (PA) may account for as much as 6-20% of cases of refractory hypertension referred to hypertension clinics."5.35The cutoff value of aldosterone-to-renin ratio for the diagnosis of primary aldosteronism in patients taking antihypertensive medicine. ( Fukuchi, K; Horio, T; Iwanaga, Y; Kamide, K; Kawano, Y; Nakahama, H; Nakamura, S; Nakata, H; Niizuma, S; Yoshihara, F, 2008)
"Aldosterone promotes renal fibrosis via the mineralocorticoid receptor (MR), thus contributing to hypertension-induced nephropathy."5.35Hypertension-induced renal fibrosis and spironolactone response vary by rat strain and mineralocorticoid receptor gene expression. ( Camp, JR; Cavallari, LH; Fashingbauer, LA; Geenen, DL; King, ST, 2008)
"Treatment with camostat mesilate or FOY-251 decreased equivalent current (Ieq) in M-1 cells in a dose-dependent manner and inhibited the protease activity of prostasin in vitro."5.35Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension. ( Adachi, M; Kakizoe, Y; Kitamura, K; Ko, T; Maekawa, A; Miyoshi, T; Shiraishi, N; Tomita, K; Wakida, N, 2009)
"Primary aldosteronism (PA) is the most common secondary cause of hypertension that has recently been implicated in alterations of the immune system and progression of cardiovascular disease."5.35Primary aldosteronism can alter peripheral levels of transforming growth factor beta and tumor necrosis factor alpha. ( Carvajal, CA; Castillo, CR; Contreras, FJ; Fardella, CE; Herrada, AA; Kalergis, AM; Mosso, LM; Stehr, CB, 2009)
"Normokalaemia does not exclude primary aldosteronism as the underlying cause of hypertension."5.35[Normokalaemic primary aldosteronism due to an aldosterone-producing adrenal adenoma--Case 06/2009]. ( Guthoff, M; Horger, M; Kirchhoff, K; Kurth, R; Müssig, K; Schnauder, G, 2009)
"Insulin resistance was estimated by the homeostasis model assessment."5.35Aldosterone contributes to blood pressure variance and to likelihood of hypertension in normal-weight and overweight African Americans. ( Grim, CE; Kidambi, S; Kotchen, JM; Kotchen, TA; Krishnaswami, S, 2009)
"The hypertension was not different and virtually superimposable in WT vs."5.35The role of aldosterone in mediating the dependence of angiotensin hypertension on IL-6. ( Brands, MW; Cannon, JG; Schreihofer, DA; Sturgis, LC, 2009)
"Liddle's syndrome is an autosomal dominant form of human hypertension, caused by gain-of-function mutations of the epithelial sodium channel (ENaC) which is expressed in aldosterone target tissues including the distal colon."5.35Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome. ( Bertog, M; Cuffe, JE; Hartner, A; Hilgers, KF; Hummler, E; Korbmacher, C; Porst, M; Pradervand, S; Rossier, BC, 2008)
"The aldosterone level was comparable in both groups."5.35Diastolic dysfunction is associated with insulin resistance, but not with aldosterone level in normotensive offspring of hypertensive families. ( Poredos, P; Trojar, A; Zeljko, T; Zizek, B, 2008)
"In patients with primary aldosteronism, as a whole group, the cut-off value of 69 corresponded to the best compromise value between sensitivity (96%) and specificity (85%), with and without PRA adjustment."5.35Plasma and urine aldosterone to plasma renin activity ratio in the diagnosis of primary aldosteronism. ( Bardini, M; Bernini, G; Bernini, M; Berti, P; Miccoli, P; Moretti, A; Orlandini, C; Salvetti, A; Taurino, C, 2008)
"Aldosterone is a mineral corticoid hormone that is produced in response to angiotensin-II, and like angiotensin-II, stimulates inflammation, oxidative stress, and fibrosis by activating nuclear factor-kappaB and activating protein-1."5.35Crosstalk between the heme oxygenase system, aldosterone, and phospholipase C in hypertension. ( Jadhav, A; Lane, N; Ndisang, JF, 2008)
"ACTH-induced-hypertension is commonly employed as a model of stress-related hypertension, and despite extensive investigation, the mechanisms underlying elevated blood pressure (BP) are not well understood."5.35ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit. ( Dostanic-Larson, I; Lasko, V; Lingrel, JB; Loreaux, EL; Lorenz, JN; Paul, RJ; Schnetzer, JR, 2008)
"Primary aldosteronism (PA) is characterized by the onset of both cardiac and gluco-metabolic alterations."5.34Aldosterone as a key mediator of the cardiometabolic syndrome in primary aldosteronism: an observational study. ( Agostinelli, L; Boscaro, M; Giacchetti, G; Mantero, F; Rilli, S; Ronconi, V; Turchi, F, 2007)
"Essential hypertension is a disease multifactorially triggered by genetic and environmental factors."5.34Analysis of renin-angiotensin-aldosterone system gene polymorphisms in resistant hypertension. ( Barros, M; Bittencourt, I; Cabello, PH; Cordovil, IL; Dolinsky, LC; Freitas, SR; Lima, AB; Moura-Neto, RS, 2007)
"Primary aldosteronism (PA) has been considered a rare cause of hypertension."5.34Prevalence of primary aldosteronism among unselected hypertensive patients: a prospective study based on the use of an aldosterone/renin ratio above 25 as a screening test. ( Fogari, E; Fogari, R; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A, 2007)
"Here we describe a 13-yr-old girl with primary hyperaldosteronism secondary to aldosterone-secreting adenoma."5.34An additional child case of an aldosterone-producing adenoma with an atypical presentation of peripheral paralysis due to hypokalemia. ( Acikalin, MF; Dinleyici, EC; Dogruel, N; Ilhan, H; Oztelcan, B; Tokar, B, 2007)
"Recent reports suggesting that primary aldosteronism (PA) is more common than historically thought have often relied on use of the plasma aldosterone concentration (PAC) to plasma renin activity (PRA) ratio (ARR) to identify patients with PA."5.33Validity of plasma aldosterone-to-renin activity ratio in African American and white subjects with resistant hypertension. ( Calhoun, DA; Cofield, S; Nishizaka, MK; Pratt-Ubunama, M; Zaman, MA, 2005)
"A total of 25 patients with primary aldosteronism caused by Conn's adenoma, 29 patients with renovascular hypertension, and 29 patients with essential hypertension (EHT) were included in the present study."5.33Role of aldosterone in left ventricular hypertrophy in hypertension. ( Fujii, K; Iida, M; Matsumura, K; Oka, M; Oniki, H, 2006)
"Resistant hypertension is common in clinical practice."5.33Aldosterone and refractory hypertension: a prospective cohort study. ( Calò, LA; Cattelan, F; Ciccariello, L; De Toni, R; Macchini, L; Mascagna, V; Pessina, AC; Realdi, A; Sartori, M; Semplicini, A, 2006)
"Primary aldosteronism has recently been recognized as the most frequent cause of secondary hypertension."5.33Confirmatory testing in normokalaemic primary aldosteronism: the value of the saline infusion test and urinary aldosterone metabolites. ( Beuschlein, F; Maser-Gluth, C; Nickel, C; Reincke, M; Rüdiger, F; Schirpenbach, C; Seiler, L, 2006)
"To screen primary aldosteronism cases with ARR (aldosterone/plasma renin activity, ARR) from patients with hypertension, and to evaluate the diagnosis value of ARR in primary aldosteronism cases and analysis the clinical characters of primary aldosteronism cases."5.33[Aldosterone/plasma renin activity ratio is a sensitive parameter for screening patients with primary aldosteronism]. ( Liu, ZJ; Shao, JM; Wang, DW; Yan, JT; Zhang, HL, 2006)
"Liddle's syndrome is a monogenic form of hypertension caused by mutations in the PY motif of the COOH terminus of beta- and gamma-epithelial Na+ channel (ENaC) subunits."5.32Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin. ( Auberson, M; Hoffmann-Pochon, N; Kellenberger, S; Schild, L; Vandewalle, A, 2003)
"Increased bioavailability of reactive oxygen species (ROS) has been implicated in the pathogenesis of mineralocorticoid hypertension."5.32NAD(P)H oxidase inhibitor prevents blood pressure elevation and cardiovascular hypertrophy in aldosterone-infused rats. ( Park, JB; Park, MY; Park, YM; Suh, YL, 2004)
"The severity of obstructive sleep apnea (OSA) correlates with the difficulty of controlling BP."5.32Aldosterone excretion among subjects with resistant hypertension and symptoms of sleep apnea. ( Calhoun, DA; Harding, SM; Nishizaka, MK; Zaman, MA, 2004)
"Obstructive sleep apnea can be detected with a careful history and various sleep studies."5.32Resistant hypertension, obesity, sleep apnea, and aldosterone: theory and therapy. ( Calhoun, DA; Goodfriend, TL, 2004)
"Primary hyperaldosteronism is a well-recognized cause of secondary hypertension."5.32Serum aldosterone and the incidence of hypertension in nonhypertensive persons. ( Benjamin, EJ; Evans, JC; Larson, MG; Levy, D; Meigs, JB; Rifai, N; Vasan, RS; Wilson, PW, 2004)
"Overweight and obesity are frequently associated with increased plasma levels of aldosterone suggesting a direct link between obesity hypertension and increased mineralocorticoid levels."5.32Fat cells may be the obesity-hypertension link: human adipogenic factors stimulate aldosterone secretion from adrenocortical cells. ( Arakelyan, K; Bornstein, SR; Ehrhart-Bornstein, M; Krug, AW; Scherbaum, WA, 2004)
"In patients with primary aldosteronism treated with spironolactone (n = 8), renin escaped suppression and reached very high levels."5.31Influence of antihypertensive medication on aldosterone and renin concentration in the differential diagnosis of essential hypertension and primary aldosteronism. ( Hahn, EG; Hensen, J; Schobel, H; Seifarth, C; Trenkel, S, 2002)
"The prevalence of primary aldosteronism (PA) was assessed in a specialized hypertension center."5.31High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives. ( Davoli, S; Negro, A; Perazzoli, F; Regolisti, G; Rossi, E; Sani, C, 2002)
"To measure the effects of hyperinsulinemia on serum electrolyte status and associated hormones, and on serum free fatty acid (FFA) concentrations, in patients with essential hypertension."5.31Serum aldosterone changes during hyperinsulinemia are correlated to body mass index and insulin sensitivity in patients with essential hypertension. ( Haenni, A; Lind, L; Lithell, H; Reneland, R, 2001)
"Gestational hypertension is a multisystem disorder which always resolves itself after delivery; its primary pathology still remains incompletely clarified."5.31The renin-aldosterone system during normal and hypertensive pregnancy. ( Creatsas, G; Elsheikh, A; Loutradis, D; Mastorakos, G; Michalas, S; Milingos, S, 2001)
"The traditional workup for primary aldosteronism is cumbersome and requires discontinuing antihypertensive medications, which is inconvenient and potentially dangerous."5.31Screening for primary aldosteronism without discontinuing hypertensive medications: plasma aldosterone-renin ratio. ( Ahmad, S; Davidson, RC; Gallay, BJ; Toivola, B; Xu, L, 2001)
"In 92 patients with chronically treated essential hypertension, two-dimensional and Doppler echocardiographic examinations were performed and LV inflow velocities were measured for evaluation of LV diastolic function."5.31Influence of plasma aldosterone on left ventricular geometry and diastolic function in treated essential hypertension. ( Horio, T; Iwashima, Y; Kawano, Y; Kuroda, S; Takishita, S, 2002)
"Also, 17 patients with known primary aldosteronism were retrospectively examined."5.31Ratio of serum aldosterone to plasma renin concentration in essential hypertension and primary aldosteronism. ( Hahn, EG; Hensen, J; Schobel, H; Seifarth, C; Trenkel, S, 2002)
"Hyperaldosteronism has been causally linked to myocardial interstitial fibrosis experimentally, but it remains unclear if this link also applies to humans."5.31Excess aldosterone is associated with alterations of myocardial texture in primary aldosteronism. ( Bertini, A; Cesari, M; Di Bello, V; Ganzaroli, C; Giorgi, D; Mariani, M; Pessina, AC; Rossi, GP; Sacchetto, A; Scognamiglio, R, 2002)
"The patients with hypertension were enrolled as research objects and the captopril challenge test were carried out when they were hospitalized to screen the cause of hypertension."5.30[The correlation between the carotid artery plaque and the change of aldosterone level related indexes during captopril challenge test]. ( Lei, YF; Li, M, 2019)
"Liddle's syndrome is an autosomal dominant form of hypertension that resembles primary hyperaldosteronism, is characterized by the early onset of hypertension with hypokalemia and suppression of both PRA and aldosterone, and is caused by mutations in the carboxyl-terminus of the beta- or gamma-subunits of the renal epithelial sodium channel."5.30Liddle's syndrome: prospective genetic screening and suppressed aldosterone secretion in an extended kindred. ( Findling, JW; Hansson, JH; Lifton, RP; Raff, H, 1997)
"A case of primary hyperaldosteronism and cardiomegaly due to a unilateral adrenal adenoma in a newborn is presented."5.30Hypertensive cardiomegaly caused by an aldosterone-secreting adenoma in a newborn. ( Armanini, D; Cecchetto, G; Fassina, A; Opocher, G; Pozzan, GB; Rigon, F; Zacchello, F, 1997)
"Aldosterone levels during treatment [13."5.30Evidence for persistent dysfunction of wild-type aldosterone synthase gene in glucocorticoid-treated familial hyperaldosteronism type I. ( Gartside, MG; Gordon, RD; Stowasser, M; Taylor, WL; Tunny, TJ, 1997)
"Aldosterone-salt treatment induced, (1) arterial hypertension (+40%) and LV hypertrophy (+60%) without altering LV-fractional shortening, (2) an increase in plasma norepinephrine levels (+262%) and suppression of renin activity."5.30Modifications of myocardial Na+,K(+)-ATPase isoforms and Na+/Ca2+ exchanger in aldosterone/salt-induced hypertension in guinea pigs. ( Carayon, A; Charlemagne, D; Lechat, P; Mougenot, N; Ramírez-Gil, JF; Trouvé, P, 1998)
"Cardiac fibrosis is linked to aldosterone-induced hypertension, but the effects on in vivo left ventricular (LV) function are not established."5.30In vivo left ventricular function and collagen expression in aldosterone/salt-induced hypertension. ( Charlemagne, D; Delcayre, C; Lechat, P; Mougenot, N; Ramirez-Gil, JF; Robert, V; Trouve, P; Wassef, M, 1998)
"Because essential hypertension is partly genetic, it is possible that altered control of aldosterone synthase gene expression or translation may be responsible."5.30Aldosterone excretion rate and blood pressure in essential hypertension are related to polymorphic differences in the aldosterone synthase gene CYP11B2. ( Anderson, NH; Connell, JM; Davies, E; Fraser, R; Friel, EC; Holloway, CD; Inglis, GC; Ingram, MC; Morrison, C, 1999)
"Normotensive primary hyperaldosteronism is exceedingly rare."5.30Aldosterone-producing adenoma without hypertension: a report of two cases. ( Ghulam, A; Jeunemaitre, X; Lefebvre, J; Provost, F; Ronci, N; Tabarin, A; Vantyghem, MC, 1999)
"Neurofibromatosis type 1 is a phacomatosis."5.30A case of neurofibromatosis type 1 with an aldosterone-producing adenoma of the adrenal. ( Alessandri, M; Biagi, P; Campanella, G; Castro, R; Fanciullacci, M; Totteri, A, 1999)
"Nephrocalcinosis was still present 8 years later and hypertension was recurring obviously as a consequence of increased peripheral resistance."5.29Aldosterone and testosterone producing adrenal adenoma in childhood. ( Burda, G; Frisch, H; Neuhold, N; Schmitt, K; Schober, E, 1995)
"In patients with primary aldosteronism and renovascular hypertension the plasma aldosterone level was shown to be an important factor upregulating AT1 receptor mRNA."5.29Angiotensin II type 1 receptor messenger RNA levels in human blood cells of patients with primary and secondary hypertension: reference to renin profile. ( Murakami, M; Saruta, T; Sato, A; Shibata, H; Suzuki, H, 1994)
"Spironolactone treatment (50 mg/kg per day) for 7 days in deficient rats restored blood pressure and heart rate to normal levels and significantly reduced sodium levels in erythrocytes and cerebrospinal fluid."5.29Hypertension induced by a nonpressor dose of angiotensin II in kininogen-deficient rats. ( Katori, M; Kuribayashi, Y; Majima, M; Mizogami, S; Oh-ishi, S, 1994)
"Arterial hypertension is nowadays no longer considered an isolated disorder of blood pressure regulation but a multifactorial disease with metabolic and cellular deviations."5.29[Changes in humoral pressor and depressor factors in essential hypertension during lisinopril therapy]. ( Horký, K; Jáchymová, M; Jarolím, M; Jindra, A; Kolár, J; Peleska, J; Savlíková, J; Stolba, P; Umnerová, V; Vorlová, Z, 1994)
"From these data it emerges that hyperaldosteronism, as observed in these patients with CRI, is a relatively reliable marker of the extent of CRI and may occur independently of the activation of the RAA system, given that other factors, such as orthostatic stimulation, alterations in the acid-base equilibrium, and the degree of aldosterone hepatic and urinary clearance, contribute to its pathogenesis."5.29[Role of aldosterone in essential arterial hypertension complicated by chronic renal insufficiency]. ( Buracchi, P; Carletti, F; Gennari, C; Lucani, B; Martinelli, M; Nami, R; Panza, F; Pavese, G; Saia, F, 1993)
"The hyperaldosteronism could not be suppressed by dexamethasone."5.29[Unilateral autonomous aldosterone production in hyperaldosteronism suppressible by dexamethasone]. ( Haack, D; Jakob, F; Ludwig, J; Rendl, J; Schröder, K; Seufert, J; Vecsei, P, 1993)
"The reactive fibrosis is thought to be related to MC excess, while cell loss and microscopic scarring may be secondary to enhanced potassium excretion or a cytotoxic effect of aldosterone."5.29Myocardial fibrosis in the rat with mineralocorticoid excess. Prevention of scarring by amiloride. ( Campbell, SE; Janicki, JS; Matsubara, BB; Weber, KT, 1993)
"Spironolactone, however, was able to prevent myocardial fibrosis in RHT and aldosterone models of acquired arterial hypertension irrespective of the development of LVH and the presence of hypertension."5.29Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension. ( Brilla, CG; Matsubara, LS; Weber, KT, 1993)
"Nilvadipine appears to be an effective hypotensive agent at single daily doses of 8 mg."5.28Nilvadipine in hypertension with renal dysfunction. ( Albert, FW; Berger, HH, 1992)
"Aldosterone was analyzed by radioimmunoassay and [4-14C]aldosterone radiometabolites by high-performance liquid chromatography."5.28Aldosterone metabolism in the isolated perfused liver of R and S hypertension-prone Dahl rats. ( Egfjord, M; Olgaard, K, 1992)
"Aldosterone-salt treatment produced decreased vascular sensitivity to acetylcholine and nitroprusside in both Wistar and Wistar-Furth rats."5.28Vascular responsiveness in rats resistant to aldosterone-salt hypertension. ( Bruner, CA, 1992)
"Captopril treatment should be introduced carefully since not all those patients at risk of hypotension can be identified in advance."5.28First dose hypotension after captopril; can it be predicted? A study of 240 patients. ( de Boo, T; Dennesen, PJ; Postma, CT; Thien, T, 1992)
"In conclusion, hypertension is a common problem in acromegaly and at least in part related to similar risk factors in control populations."5.28Acromegaly and hypertension: prevalence and relationship to the renin-angiotensin-aldosterone system. ( Benker, G; Hirche, H; Kraatz, C; Lüdecke, D; Reinwein, D; Weber, F, 1990)
"Aldosterone was preferentially metabolized to THA in LRH."5.28Alterations in aldosterone secretion and metabolism in low renin hypertension. ( Griffing, GT; Melby, JC; Wilson, TE, 1990)
" The purpose of the present study was to examine whether long-term therapy with ramipril (RA, and ACE inhibitor) would lower blood pressure more effectively and without adverse reactions in combination with the loop diuretics piretanide (PI) or furosemide (FU)."5.28Loop diuretics combined with an ACE inhibitor for treatment of hypertension: a study with furosemide, piretanide, and ramipril in spontaneously hypertensive rats. ( Baldes, L; Becker, RH; Treudler, M, 1989)
"1."5.28Endogenous digoxin-like immunoreactive factor and digitalis-like factor associated with the hypertension of patients receiving multiple alkylating agents as part of autologous bone marrow transplantation. ( Antman, KH; Brena, A; Eder, JP; Graves, SW; Peters, WP; Schryber, SM; Sharma, K, 1989)
"Bopindolol was given to hypertensive patients in a single daily dose ranging from 1 to 4 mg."5.28Bopindolol: long-term effects on blood pressure, renal function, plasma renin activity, and plasma aldosterone in mild-to-moderate essential hypertension. ( Modan, M; Rosenfeld, JB; Shohat, J, 1989)
"Minoxidil was used in 48 patients with AH of varying clinical forms, 19 of those having the malignant AH syndrome."5.27[Use of angiotensin converting enzyme inhibitor captopril and peripheral vasodilator minoxidil in the treatment of patients with stable and malignant arterial hypertension]. ( Arabidze, GG; Kutsenko, AI; Leshchinskiĭ, PM; Lordkipanidze, NL; Masenko, VP, 1983)
"Most diagnostic tests for primary aldosteronism use maneuvers to expand the extracellular fluid volume, thereby suppressing the renin-angiotensin system."5.27Single dose captopril as a diagnostic test for primary aldosteronism. ( Brown, RD; Carollo, ML; Hanson, CS; Kem, DC; Lyons, DF, 1983)
"Primary aldosteronism is a potentially curable cause of hypertension; it occurs in about 1% of hypertensive patients."5.27'Essential' hypertension with hypokalemia. Caused by aldosterone-secreting adrenal adenoma. ( Almog, C; Burke, M; Papo, J; Stavorovsky, M, 1984)
"Ketanserin is a serotonin antagonist with high affinity for S2-serotonergic receptors, which mediate the vasoconstrictor effects of serotonin."5.27Ketanserin: a possible tool for studying the role of serotonin in hypertension. ( Boomsma, F; Man in't Veld, AJ; Schalekamp, MA; Wenting, GJ; Woittiez, AJ, 1985)
"Hyperaldosteronism was associated with the most pronounced deviations in the relationship between stimulants and aldosterone."5.27[Concentration of adrenocorticotrophic hormone and aldosterone secretion in essential hypertension and hyperaldosteronism]. ( Chikhladze, NM; Pershakova, LP; Shkhvatsabaia, IK; Uchitel', IA; Ustinova, SE, 1985)
"Enalapril (MK-421) was administered orally as a single dose of 2."5.27Effect of enalapril on renin, angiotensin converting enzyme activity, aldosterone and prostaglandins in patients with hypertension. ( Genest, J; Gutkowska, J; Hamet, P; Kuchel, O; Larochelle, P; Schiffrin, E, 1985)
"Mean captopril doses used were similar in both groups."5.27Effects of converting enzyme inhibition on blood pressure, plasma renin activity (PRA) and plasma aldosterone in hypertensive diabetics compared to patients with essential hypertension. ( Dineen, M; Kelleher, M; Sullivan, PA; Twomey, M, 1985)
"Treatment with spironolactone alone for 2 months corrected hypertension, hypokalemic alkalosis, and all laboratory and radiologic evidence of rickets and hyperparathyroidism, resulting in acceleration of growth rate."5.27Spironolactone-reversible rickets associated with 11 beta-hydroxysteroid dehydrogenase deficiency syndrome. ( Arnhold, IJ; Batista, MC; Bloise, W; Kater, CE; Mendonça, BB; Nicolau, W; Rocha, A, 1986)
" Enalapril in a dosage of 20 mg/day significantly and progressively lowered systolic and diastolic blood pressure at rest, with maximal decreases observed on the 120th day of the study period (P less than 0."5.27Effects of enalapril maleate on blood pressure, renin-angiotensin-aldosterone system, and peripheral sympathetic activity in essential hypertension. ( Carapelle, E; Carone, MB; Cerasola, G; Contorno, A; Cottone, S; D'Ignoto, G; Grasso, L, 1987)
"Aldosterone only was elevated in 3 cases, while PRA was elevated in 2."5.27The pattern of plasma renin activity and aldosterone system in patients with sustained hydronephrosis. ( Ezzat, M, 1987)
"Hyperaldosteronism in the patients with renal-parenchymatous and essential arterial hypertension was regarded as secondary in a stable and malignant course of arterial hypertension."5.27[Radioimmunologic determination of aldosterone and renin in the blood in the diagnosis of different forms of arterial hypertension]. ( Khalmuratova, RA; Khamidov, RI; Sattarova, FK, 1987)
"Minoxidil treatment lowered blood pressure from 178/112 +/- 8/5 mm Hg (means +/- SEM) to 14/95 +/- 6/3 mm Hg."5.26Treatment of drug-resistant hypertension with minoxidil or angiotensin-converting enzyme inhibitor: blood pressure, renin, aldosterone, and electrolyte responses. ( Baer, L; Radichevich, I; Williams, GS, 1980)
"Captopril was given in biweekly, doubling doses starting with 25 mg 3 times a day until control of blood pressure was achieved or a total daily dosage of 600 mg was reached."5.26Dose response in captopril therapy of hypertension. ( Amery, A; Fagard, R; Lijnen, P; Staessen, J; Verschueren, LJ, 1980)
"Captopril was given to pregnant and nonpregnant animals during the developmental phase of hypertension and to nonpregnant animals with established (4 weeks of treatment) hypertension."5.26Aldosterone-induced hypertension: effects of a kininase inhibitor. ( Douglas, BH; Evans, TA; Lundy, JH; Parks, BR, 1980)
"Enalapril was well tolerated."5.26Effects of enalapril, a new converting enzyme inhibitor, in hypertension. ( Ferguson, RK; Hichens, M; Huber, PB; Irvin, JD; Mojaverian, P; Swanson, BN; Vlasses, PH, 1982)
"PGF2 alpha was the same in preeclampsia and normotensive pregnancy but higher than in the non-pregnant group."5.26Prostaglandins, catecholamines, renin and aldosterone during hypertensive and normotensive pregnancy. ( Christensen, NJ; Christensen, P; Johannesen, P; Kornerup, HJ; Kristensen, S; Lauritsen, JG; Leyssac, PP; Pedersen, EB; Rasmussen, AB; Wohlert, M, 1982)
"Screening tests for primary aldosteronism were compared in 22 patients with this disorder and 140 hypertensive controls."5.26Simplified screening procedures for primary aldosteronism. Studies on the mechanism of the hyper-responsiveness to furosemide and standing. ( Anderson, GH; Streeten, DH, 1982)
"Aldosterone excretion was established to be normal in 55."5.26[Urinary excretion of aldosterone in patients with hypertension]. ( Elenkova, A; Grigorova, R, 1982)
"Captopril was used in primary and long-term treatment of 40 treatment-resistant hypertensive patients."5.26Long-term efficacy of captopril in renovascular and essential hypertension. ( Atlas, SA; Case, DB; Laragh, JH; Marion, RM, 1982)
"Twenty-four patients with primary aldosteronism were studied."5.26Fludrocortisone suppression test in normal subjects, in patients with essential hypertension and in patients with various forms of aldosteronism. ( Lund, JO; Nielsen, MD, 1980)
"In primary aldosteronism, high UA and PAC together with suppressed PRA represent an important diagnostic guideline for differentiation from other types of low-renin hypertensions."5.26Renin-angiotensin-aldosterone system in arterial hypertension. ( Gregorová, I; Horký, K, 1980)
"Captopril (SQ 14."5.26Captopril in primary hypertension. Effects related to the renin-angiotensin-aldosterone and kallikrein-kinin systems. ( Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S, 1981)
"1."5.26Effect of angiotensin II and converting enzyme inhibitor (captopril) on blood pressure, plasma renin activity and aldosterone in primary aldosteronism. ( Armanini, D; Boscaro, M; Fallo, F; Mantero, F; Opocher, G; Scaroni, C, 1981)
"Low-renin hypertension was diagnosed by the presence of hypertension, hypokalaemic alkalosis, suppressed plasma renin activity and low plasma aldosterone."5.26Low-renin, low-aldosterone hypertension and abnormal cortisol metabolism in a 19-month-old child. ( Fiselier, TJ; Honour, JW; Monnens, LA; Otten, BJ; van Munster, PJ, 1982)
"In most of the patients examined hyperaldosteronism was found, which was attended by an increased percentage of 14C-aldosterone binding with aldosterone binding globulin (ABG) and particularly with glucocorticoid binding globulin (GBG)."5.26[14C-aldosterone binding by plasma proteins in adolescents with primary arterial hypertension]. ( Bakova, VV; Golov, AG; Kucherenko, AG; Markov, KhM, 1981)
"Four patients with hyperaldosteronism due to adrenal adenomas served as controls."5.26The role of ACTH in the episodic release of aldosterone in patients with idiopathic adrenal hyperplasia, hypertension, and hyperaldosteronism. ( Gomez-Sanchez, C; Higgins, JR; Kem, DC; Kramer, NJ; Weinberger, MH, 1976)
"High aldosterone was more often in patients with high renin, and low levels of aldosterone were usual in those with low and normal renin."5.26The mechanism of low-renin hypertension: aldosterone response to sodium restriction and upright posture, angiotensin II, ACTH and potassium in patients with hypertension. ( Kondo, K; Matsuki, S; Misumi, J; Nakamura, R; Saito, I; Saruta, T, 1976)
"These data show that patients with hyperaldosteronism from an adrenal adenoma or hyperplasia have a consistent and exaggerated response to ACTH."5.26Plasma aldosterone response to ACTH in primary aldosteronism and in patients with low renin hypertension. ( Gomez-Sanchez, C; Higgins, JR; Holland, OB; Kem, DC; Kramer, NJ; Weinberger, MH, 1978)
""Outpatient hyperkalemia" is a new clinical syndrome in which high serum potassium levels (SK) are found in the outpatient condition returning toward normal without any specific treatment after admission to the hospital."5.26"Outpatient hyperkalemia" syndrome in renal and hypertensive patients with suppressed aldosterone production. ( Boer, P; Dorhout Mees, EJ; Rado, JP; Simatupang, T, 1979)
"Experimental toxemia of pregnancy was induced in 8 pregnant monkeys (Macacamulatta) by reducing the abdomiinal aorta to one-third of its original diameter during the last month of gestation."5.26Experimental toxemia of pregnancy in the monkey, with a preliminary report on renin and aldosterone. ( Abitbol, MM; Driscoll, SG; Gallo, GR; Ober, MB; Pirani, CL, 1977)
" The findings indicate that different regulatory mechanisms are activated during acute and chronic administration of nifedipine."5.26Effect of nifedipine on plasma renin, aldosterone and catecholamines in arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Mikkelsen, E; Pedersen, EB; Pedersen, OL, 1979)
"1."5.26Blood pressure reduction by incremental infusion of labetalol in patients with severe hypertension. ( Brown, JJ; Cummings, AM; Fraser, R; Lever, AF; Morton, JJ; Richards, DA; Robertson, JI, 1979)
" The data shows that this dosage of spironolactone gave minor adjustments of the systemic and renal circulation in spite of the consistent changes in BW, PV, PRA and PA."5.26Haemodynamic effects of treatment and withdrawal of spironolactone in essential hypertension. ( Falch, DK; Johansson, R; Norman, N; Odegaard, AE, 1979)
"Triamterene was administered in a dose of 100 mg/day for 8 days to 7 patients with essential hypertension."5.26Effect of triamterene on urinary excretion of immunoreactive prostaglandin E in essential hypertension. ( Abe, K; Chiba, S; Irokawa, N; Ito, T; Otsuka, Y; Saito, K; Sakurai, Y; Sato, M; Yasujima, M; Yoshinaga, K, 1979)
"Twenty patients suffering from primary hyperaldosteronism were studied."5.26[The renin-angiotensin-aldosterone system in hypertensive patients. II. Diagnosis of primary hyperaldosteronism]. ( Benguigui, L; Corvol, P; Houde, M; Menard, J; Milliez, P; Tonnelier, M, 1977)
"Hypertension was produced in 25 rabbits by constricting the right renal artery and leaving the opposite kidney intact (two-kidney hypertension)."5.26Renin-angiotensin-aldosterone system in experimental renal hypertension in the rabbit. ( Davis, JO; Lohmeier, TE, 1976)
"Five obvious cases of hyperaldosteronism were found among the 16 low-renin patients."5.25Abnormally sustained aldosterone secretion during salt loading in patients with various forms of benign hypertension; relation to plasma renin activity. ( Collins, RD; Dowdy, AJ; Gonzales, CM; Luetscher, JA; Nokes, GW; Weinberger, MH, 1970)
" Prostasin was measured in plasma and urine from type 2 diabetic patients with resistant hypertension (n = 112) randomized to spironolactone/placebo in a clinical trial."5.24Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin. ( Bistrup, C; Hansen, MR; Hansen, PB; Hinrichs, GR; Jacobsen, IA; Jensen, BL; Kurt, B; Oxlund, C; Schwarzensteiner, I; Stæhr, M; Svenningsen, P; Thuesen, AD; Toft, A, 2017)
"Angiotensin II receptor blockers (ARBs) have been widely used to treat hypertension and large-scale clinical studies have shown various benefits."5.22Changeover Trial of Azilsartan and Olmesartan Comparing Effects on the Renin-Angiotensin-Aldosterone System in Patients with Essential Hypertension after Cardiac Surgery (CHAOS Study). ( Arimoto, M; Hata, H; Osaka, S; Sakino, H; Sezai, A; Shiono, M; Yaoita, H, 2016)
"To address the cardiovascular mechanisms involved in response to an angiotensin II receptor antagonist, losartan, and continuous positive airway pressure (CPAP) as add-on treatment for hypertension and OSA."5.22Neuroendocrine and Inflammatory Responses to Losartan and Continuous Positive Airway Pressure in Patients with Hypertension and Obstructive Sleep Apnea. A Randomized Controlled Trial. ( Lindberg, C; Manhem, K; Peker, Y; Rosengren, A; Thunström, E; Yucel-Lindberg, T, 2016)
"This exploratory study reports two plausible loci associated with SBP response to hydrochlorothiazide: TET2, an aldosterone-responsive mediator of αENaC gene transcription; and CSMD1, previously described as associated with hypertension in a case-control study."5.20TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives. ( Argiolas, G; Barlassina, C; Boerwinkle, E; Braga, D; Carpini, SD; Chapman, AB; Chittani, M; Citterio, L; Condorelli, G; Cooper-Dehoff, RM; Cusi, D; Dominiczak, AF; Donner, KM; Frau, F; Fresu, G; Glorioso, N; Glorioso, V; Gong, Y; Hiltunen, TP; Johnson, JA; Kontula, KK; Lanzani, C; Manunta, P; Melander, O; Ortu, MF; Padmanabhan, S; Piras, DA; Pozzoli, S; Rivera, NV; Salvi, E; Simonini, M; Trimarco, B; Troffa, C; Turner, ST; Velayutham, D; Zaninello, R, 2015)
"A total of 48 patients with untreated hypertension were randomly assigned to irbesartan (ARB group, n=26) and amlodipine (CCB group, n=22)."5.19Long-term effects of irbesartan on plasma aldosterone concentration and left atrial volume in hypertensive patients. ( Fujiwara, S; Fukui, M; Goda, A; Hirotani, S; Komamura, K; Koshiba, M; Lee-Kawabata, M; Masaki, M; Masuyama, T; Nakabo, A; Otsuka, M; Sugahara, M; Tsujino, T, 2014)
"5 mg hydrochorothiazide + 5 mg amlodipine, 86 patients with resistant hypertension were randomized to the add-on 25 mg spironolactone (MRB group, n = 46) or 5 mg ramipril (RASB group, n = 40) groups for 12 weeks."5.19Greater efficacy of aldosterone blockade and diuretic reinforcement vs. dual renin-angiotensin blockade for left ventricular mass regression in patients with resistant hypertension. ( Azizi, M; Bobrie, G; Chatellier, G; Frank, M; Ménard, J; Perdrix, L; Plouin, PF, 2014)
"The purpose of this study was to evaluate the effects of spironolactone on dialysis patients with refractory hypertension and possible adverse effects."5.19Effects of spironolactone on dialysis patients with refractory hypertension: a randomized controlled study. ( Chen, J; Ni, X; Wu, F; Xia, M; Ying, G; Zhang, J; Zhang, P, 2014)
"The aim was to compare the antiproteinuric effect of aliskiren and ramipril in hypertensive patients with type 2 diabetes and microalbuminuria."5.17Time course of antiproteinuric effect of aliskiren in arterial hypertension associated with type 2 diabetes and microalbuminuria. ( Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Perrone, T; Preti, P; Zoppi, A, 2013)
"The primary objective of this study was to evaluate the antihypertensive effect of low dose spironolactone added to triple therapy for resistant hypertension in patients with type 2 diabetes measured by ambulatory monitoring."5.17Low dose spironolactone reduces blood pressure in patients with resistant hypertension and type 2 diabetes mellitus: a double blind randomized clinical trial. ( Gram, J; Henriksen, JE; Jacobsen, IA; Oxlund, CS; Schousboe, K; Tarnow, L, 2013)
"We aimed to assess the effect of aliskiren treatment on blood pressure, albuminuria, and kidney function in patients with chronic kidney disease (CKD)."5.17Efficacy analysis of the renoprotective effects of aliskiren in hypertensive patients with chronic kidney disease. ( Abe, M; Baba, S; Inoshita, A; Maruyama, N; Okada, K; Soma, M; Suzuki, H; Takashima, H, 2013)
" We conducted an open-label, randomized trial to compare the effects of cilnidipine against those of amlodipine on blood pressure (BP), albuminuria, and plasma aldosterone concentration in hypertensive patients with mild- to moderate-stage chronic kidney disease."5.17L/N-type calcium channel blocker cilnidipine reduces plasma aldosterone, albuminuria, and urinary liver-type fatty acid binding protein in patients with chronic kidney disease. ( Abe, M; Inoshita, A; Maruyama, N; Okada, K; Soma, M; Suzuki, H; Yoshida, Y, 2013)
" We wanted to test the hypotheses that amiloride and spironolactone induced potassium retention reduces ambulatory blood pressure (ABP) and central blood pressure (CBP) during baseline conditions and after furosemide and that the tubular transport via the epithelial sodium channels (ENaCs) and aquaporin-2 (AQP2) water channels was increased by furosemide in arterial hypertension."5.17Effect of amiloride and spironolactone on renal tubular function and central blood pressure in patients with arterial hypertension during baseline conditions and after furosemide: a double-blinded, randomized, placebo-controlled crossover trial. ( Jensen, JM; Larsen, T; Lauridsen, TG; Matthesen, SK; Pedersen, EB; Vase, H, 2013)
"We measured urinary excretion of AQP2 and ENaC β-subunit corrected for creatinine (u-AQP2(CR), u-ENaC(β-CR)), prostaglandin E2 (u-PGE2) and cyclic AMP (u-cAMP), fractional sodium excretion (FE(Na)), free water clearance (C(H2O)), as well as plasma concentrations of vasopressin (AVP), renin (PRC), angiotensin II (Ang II), aldosterone (Aldo), and atrial and brain natriuretic peptide (ANP, BNP) in 21 patients with essential hypertension and 20 normotensive controls during 24-h urine collection (baseline), and after hypertonic saline infusion on a 4-day high sodium (HS) diet (300 mmol sodium/day) and a 4-day low sodium (LS) diet (30 mmol sodium/day)."5.16Abnormal increase in urinary aquaporin-2 excretion in response to hypertonic saline in essential hypertension. ( Bech, JN; Graffe, CC; Lauridsen, TG; Pedersen, EB; Vase, H, 2012)
" In this study, we conducted an open-label and randomized trial to compare the effects of benidipine with those of amlodipine on blood pressure (BP), albuminuria and aldosterone concentration in hypertensive patients with mild-to-moderate stage chronic kidney disease (CKD)."5.15Benidipine reduces albuminuria and plasma aldosterone in mild-to-moderate stage chronic kidney disease with albuminuria. ( Abe, M; Fujita, T; Maruyama, N; Maruyama, T; Matsumoto, K; Matsumoto, S; Okada, K; Soma, M, 2011)
"The Ouabain and Adducin for Specific Intervention on Sodium in Hypertension (OASIS-HT) Trial was a phase-2 dose-finding study of rostafuroxin, a digitoxygenin derivative, which selectively antagonizes the effects of endogenous ouabain (EO) on Na+,K+-ATPase and mutated adducin."5.15Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin. ( Bacchieri, A; Barton, J; Bianchi, G; Citterio, L; de Leeuw, PW; Dłużniewski, M; Espositi, ED; Ferrari, P; Glorioso, N; Januszewicz, A; Kawecka-Jaszcz, K; Lanzani, C; Manunta, P; Milyagin, V; Nikitin, Y; Souček, M; Staessen, JA; Stolarz-Skrzypek, K; Thijs, L; Timio, M; Tykarski, A; Valentini, G, 2011)
"The Aliskiren in Left Ventricular Hypertrophy (ALLAY) trial randomised 465 hypertensive overweight subjects with LVH to the direct renin inhibitor aliskiren 300 mg, losartan 100 mg or the combination and followed patients for 9 months."5.15Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertension. ( Appelbaum, E; Dahlöf, B; Desai, A; Lukashevich, V; Pouleur, AC; Prescott, MF; Smith, BA; Solomon, SD; Uno, H, 2011)
"Participants enrolled in this trial were outpatients with essential hypertension after cardiac surgery who had received candesartan for more than one year."5.15Effects of olmesartan on the renin-angiotensin-aldosterone system for patients with essential hypertension after cardiac surgery--investigation using a candesartan change-over study. ( Hata, M; Sezai, A; Shiono, M; Soma, M; Unosawa, S; Wakui, S; Yoshitake, I, 2011)
"The objectives were to determine effects of spironolactone and chlorthalidone on SNA and the role of SNA on diuretic-induced insulin resistance in human hypertension."5.14Differential effects of chlorthalidone versus spironolactone on muscle sympathetic nerve activity in hypertensive patients. ( Adams-Huet, B; Arbique, D; Auchus, RJ; Menon, DV; Vongpatanasin, W; Wang, Z, 2009)
" Spironolactone is thought to be an important addition to resistant hypertension (RH) treatment."5.14Aldosterone excess or escape: Treating resistant hypertension. ( Adriana de Souza, L; Coca, A; Coelho, OR; Ferreira-Melo, S; Martins, LC; Moreno, H; Pimenta, E; Sierra, C; Ubaid-Girioli, S; Yugar-Toledo, JC, 2009)
"Forty type 2 diabetic patients with hypertension and nephropathy receiving angiotensin receptor II blockers were enrolled and randomly divided into two groups: the efonidipine group was administered efonidipine hydrochloride ethanolate 40 mg/day and the amlodipine group was admin-istered amlodipine besilate 5 mg/day for 12 months."5.14Protective effects of efonidipine, a T- and L-type calcium channel blocker, on renal function and arterial stiffness in type 2 diabetic patients with hypertension and nephropathy. ( Ban, N; Endo, K; Kawana, H; Miyashita, Y; Nagayama, D; Ohhira, M; Oyama, T; Saiki, A; Sasaki, H; Shirai, K; Yamaguchi, T, 2009)
"This study was conducted to determine the effects of a tablet combining losartan/hydrochlorothiazide (L/HCTZ) in comparison with losartan alone in Japanese diabetic patients with hypertension."5.14Safety and benefits of a tablet combining losartan and hydrochlorothiazide in Japanese diabetic patients with hypertension. ( Ichihara, A; Itoh, H; Kinouchi, K; Kurauchi-Mito, A; Sakoda, M, 2009)
"A total of 50 stable outpatients with essential hypertension who had received candesartan for more than 1 year were randomized into two groups: control group (n=25): continuous candesartan treatment at a stable dose; and olmesartan group (n=25): candesartan (8 mg day(-1)) was changed to olmesartan given at a dose of 20 mg day(-1)."5.14Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension. ( Fujii, M; Horie, M; Kawahara, C; Nishiyama, K; Tsutamoto, T; Yamaji, M; Yamamoto, T, 2010)
"A common pharmacologic test for the diagnosis of primary aldosteronism (PA) is the administration of captopril to determine whether an abnormal plasma aldosterone concentration (PAC) to plasma renin activity (PRA) ratio(ARR) persists, although active renin concentration (ARC) may offer advantages with regard to processing and standardization."5.14Diagnosis of primary aldosteronism: comparison of post-captopril active renin concentration and plasma renin activity. ( Chang, CC; Chang, HW; Chueh, SC; Fang, CC; Ho, YL; Huang, KH; Kuo, CC; Lin, CY; Lin, LY; Lin, SL; Lin, YH; Liu, KL; Tsai, CT; Wang, SM; Wu, KD; Wu, VC; Yen, RF, 2010)
"The aim of the study was evaluation of spironolactone effect on concentration of endothelin-1 (ET-1 - vasoconstrictive substance produced by endothelial cells) and aldosterone (Ald) and plasma renin activity (PRA) in patients with primary arterial hypertension (AH): group A--smoking patients (11 individuals) in comparison with group B--non-smoking ones (12 individuals)."5.14[Does spironolactone use at arterial hypertension therapy protect endothelium also in smoking patients?]. ( Kara-Perz, H; Kosicka, T; Perz, S, 2009)
" We investigated the hypothesis that simvastatin decreased muscle sympathetic nerve activity (MSNA) in 31 hypertensive subjects with hypercholesterolemia (aged 38."5.14Simvastatin reduces sympathetic activity in men with hypertension and hypercholesterolemia. ( Abramczyk, P; Bidiuk, J; Ciarka, A; Dobosiewicz, A; Gaciong, Z; Lewandowski, J; Siński, M, 2010)
"Angiotensinogen (AGT) and aldosterone play key roles in the regulation of blood pressure and are implicated in the pathogenesis of cardiovascular diseases."5.12DNA Methylation of the Angiotensinogen Gene, ( Demura, M; Takeda, Y; Yoneda, T, 2021)
"In this study we evaluated the effect of a dual blockade with enalapril and losartan on the reduction of overt macroproteinuria and its potential mechanism(s) in hypertensive patients with type 2 diabetes."5.12Dual blockade of angiotensin II with enalapril and losartan reduces proteinuria in hypertensive patients with type 2 diabetes. ( Hirata, A; Igarashi, M; Kadomoto, Y; Tominaga, M, 2006)
"The patients with essential hypertension were randomly divided into 2 groups; 1 group was treated with an ARB, candesartan (8 mg/day), for 1 year (ARB group) and other group was treated with the ARB for the first 6 months and with the ARB plus SPRL (25 mg/day) for the next 6 months (combination group)."5.12Effects of spironolactone during an angiotensin II receptor blocker treatment on the left ventricular mass reduction in hypertensive patients with concentric left ventricular hypertrophy. ( Date, T; Kawai, M; Mochizuki, S; Seki, S; Shimizu, M; Taniguchi, I; Taniguchi, M; Yoshida, S, 2006)
" It is not known if subjects with a high ratio have aldosteronism or aldosterone-sensitive hypertension is debated but it is important to know whether spironolactone is superior to other diuretics such as bendroflumethiazide in this setting."5.12Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study. ( Alhashmi, K; Connell, JM; Ford, I; MacDonald, TM; McInnes, GT; McMahon, AD; Parthasarathy, HK; Struthers, AD, 2007)
"Amlodipine is an effective treatment for hypertension."5.11Hemodynamic effects of amlodipine, bisoprolol, and lisinopril in hypertensive patients after liver transplantation. ( Alexander, GJ; Brown, MJ; Byrne, CD; Neal, DA; Wilkinson, IB, 2004)
"Renin, aldosterone, and their interrelation are influenced by circadian rhythms, telmisartan, ramipril, and amlodipine in patients with essential hypertension."5.11Effects of circadian rhythms, posture, and medication on renin-aldosterone interrelations in essential hypertensives. ( de Champlain, J; Karas, M; Lacourcière, Y; Lamarre-Cliche, M; Larochelle, P; Poirier, L, 2005)
" We investigated the additive effect of DRSP/E2 versus placebo on 24-h ambulatory blood pressure (BP) in postmenopausal women with hypertension treated with enalapril maleate (ENA)."5.10Additive effect of drospirenone/17-beta-estradiol in hypertensive postmenopausal women receiving enalapril. ( Alonso, A; Karara, AH; Panzitta, D; Preston, RA; Zhang, P, 2002)
"The aim of this study was to investigate blood pressure, renal haemodynamics, hormone secretion and the responses to angiotensin II infusion during candesartan cilexetil (candesartan), losartan potassium (losartan) and valsartan treatment in patients with essential hypertension."5.10Influence of AT1 receptor blockade on blood pressure, renal haemodynamics and hormonal responses to intravenous angiotensin II infusion in hypertensive patients. ( Andersson, OK; Elmfeldt, D; Friberg, PR; Fridman, KU; Wysocki, M, 2002)
"This study shows that spironolactone improves impaired fibrinolysis in systemic hypertension."5.10Effect of spironolactone on impaired fibrinolysis of hypertensive patients. ( Aslan, V; Dincer, M; Gulbas, Z; Yalcin, AI, 2002)
"Black (n = 348) and white (n = 203) patients with mild-to-moderate hypertension were randomized to double-blind treatment with eplerenone 50 mg, the angiotensin II receptor antagonist losartan 50 mg, or placebo once daily."5.10Efficacy and tolerability of eplerenone and losartan in hypertensive black and white patients. ( Flack, JM; Garthwaite, S; Kleiman, JH; Krause, SL; Oparil, S; Pratt, JH; Roniker, B; Saunders, E; Workman, D; Yang, Y, 2003)
"One hundred eighteen patients with mild-to-moderate essential arterial hypertension were randomized to treatment with 10 mg/d of amlodipine (group 1), 20 mg/d of quinapril (group 2), or 2 x 50 mg/d of losartan (group 3)."5.10Effect of amlodipine, quinapril, and losartan on pulse wave velocity and plasma collagen markers in patients with mild-to-moderate arterial hypertension. ( Kawecka-Jaszcz, K; Klocek, M; Rajzer, M, 2003)
"Eplerenone is a highly selective aldosterone blocking agent, which was recently approved for the treatment of hypertension and has also been shown to reduce mortality in post-myocardial infarction patients with heart failure."5.10Assessment of the novel selective aldosterone blocker eplerenone using ambulatory and clinical blood pressure in patients with systemic hypertension. ( Carr, AA; Jordan, R; Krause, S; Oigman, W; Roniker, B; White, WB, 2003)
"After confirming hypertension in the absence of antihypertensive treatment, blood pressure control was achieved by administration of amlodipine at individually adjusted doses."5.10One year follow-up of hormone replacement therapy with percutaneous estradiol and low-dose vaginal natural progesterone in women with mild to moderate hypertension. ( Castro, I; Reis, FM; Ruschel, S; Spritzer, PM; Vilodre, LC; Vitola, D; Wender, MC, 2003)
"Previous reports have demonstrated the antihypertensive efficacy of high doses of spironolactone in subjects with primary aldosteronism and, to a lesser degree, subjects with resistant hypertension."5.10Efficacy of low-dose spironolactone in subjects with resistant hypertension. ( Calhoun, DA; Nishizaka, MK; Zaman, MA, 2003)
"Patients with mild-to-moderate primary hypertension and left ventricular hypertrophy were randomized in a double-blind study to receive treatment with either the angiotensin II type 1 (AT1) receptor antagonist irbesartan (n = 43), or the beta1-adrenergic receptor blocker atenolol (n = 43)."5.10Aldosterone synthase (CYP11B2) -344 C/T polymorphism is related to antihypertensive response: result from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial. ( Hägg, A; Kahan, T; Karlsson, J; Kurland, L; Lind, L; Malmqvist, K; Melhus, H; Nyström, F; Ohman, P, 2002)
" In the present study, we examined the effect on left ventricular hypertrophy of adding a low dose of the mineralocorticoid receptor antagonist spironolactone (25 mg/d) to an angiotensin-converting enzyme inhibitor (enalapril maleate) in patients with essential hypertension."5.09Effects of spironolactone and angiotensin-converting enzyme inhibitor on left ventricular hypertrophy in patients with essential hypertension. ( Saruta, T; Sato, A; Suzuki, Y, 1999)
"To study the efficacy and tolerability of a range of valsartan doses in patients with mild-to-moderate hypertension."5.09Dose-response efficacy of valsartan, a new angiotensin II receptor blocker. ( Chiang, YT; Gatlin, M; Glazer, R; Pool, JL, 1999)
"To determine the relationship between endothelin-1 (ET-1), human atrial natriuretic peptide (hANP), plasma-renin activity (PRA) and 24-h urinary excretion of aldosterone (U-Ald) in pregnancy-induced hypertension (PIH)."5.09Plasma human atrial natriuretic peptide, endothelin-1, aldosterone and plasma-renin activity in pregnancy-induced hypertension. ( Bogdanovska, SV; Gerasimovska, BD; Lozance, LA; Maleska, VT; Masin-Paneva, J; Zafirovska, KG, 1999)
"Since renal sympathetic nerves are involved in the regulation of sodium excretion, we investigated whether treatment with urapidil, an alpha1-adrenoceptor blocking agent which also lowers sympathetic activity, alters sodium excretory capacity in patients with essential hypertension."5.09Renal haemodynamics and sodium excretory capacity during urapidil treatment in patients with essential hypertension. ( de Leeuw, PW; Fuss-Lejeune, M; Kroon, AA; Lavrijssen, AT; Schiffers, PM, 2000)
"This multicenter study evaluated the efficacy of candesartan cilexetil, an angiotensin II type 1 receptor antagonist, used alone or in combination with amlodipine or in combination with amlodipine and hydrochlorothiazide in the treatment of patients with moderate-to-severe essential hypertension."5.09Efficacy of candesartan cilexetil alone or in combination with amlodipine and hydrochlorothiazide in moderate-to-severe hypertension. UK and Israel Candesartan Investigators. ( Antonios, TF; He, FJ; MacGregor, GA; Viskoper, JR, 2000)
"We examined the effects of the vasodilator peptide adrenomedullin (AM) infused intravenously into subjects with essential hypertension."5.09Hemodynamic, hormone, and urinary effects of adrenomedullin infusion in essential hypertension. ( Lewis, LK; Nicholls, MG; Richards, AM; Troughton, RW; Yandle, TG, 2000)
"In this study we investigated the presence of the mutation D147E of CYP11B2 in a group of 128 patients with primary aldosteronism, 68 patients with essential hypertension and increased corticosterone production and in 48 normal volunteers."5.09Absence of D147E mutation of CYP11B2 gene in hypertensive patients with increased corticosterone and aldosterone production. ( Carra, R; Fallo, F; Filigheddu, F; Glorioso, N; Morra di Cella, S; Mulatero, P; Soro, A; Veglio, F, 2001)
"The aim of this study was to investigate the effect of short-term treatment with losartan, a selective and competitive angiotensin II (AngII) receptor blocker, on vascular endothelial growth factor (VEGF), active renin and kallikrein activity (KA) in patients with essential hypertension and primary aldosteronism."5.09Effect of short-term losartan treatment in patients with primary aldosteronism and essential hypertension. ( Atanassova, I; Natchev, E; Orbetzova, M; Tzingilev, D; Zacharieva, S, 2001)
"To examine the factors that determine the blood pressure response to enalapril and nifedipine monotherapy in the treatment of hypertension associated with non-insulin-dependent diabetes mellitus (NIDDM)."5.08Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM. ( Chan, JC; Cheung, CK; Cockram, CS; Law, LK; Nicholls, MG; Swaminathan, R, 1995)
"The antihypertensive effect of the angiotensin-converting enzyme inhibitor trandolapril administered in doses of 1, 2, and 4 mg/d was compared in 207 white patients and 91 black patients with mild to moderate hypertension following a double-blind, randomized, placebo-controlled, parallel study design."5.08Differing mechanisms of action of angiotensin-converting enzyme inhibition in black and white hypertensive patients. The Trandolapril Multicenter Study Group. ( Gray, JM; Paster, R; Saunders, E; Weir, MR, 1995)
"The antihypertensive effects of moexipril, a new angiotensin converting enzyme inhibitor, and verapamil-SR as add-on therapy to hydrochlorothiazide (HCTZ) were investigated in patients with moderate to severe (stages II and III) essential hypertension."5.08Comparison of moexipril, a new ACE inhibitor, to verapamil-SR as add-on therapy to low dose hydrochlorothiazide in hypertensive patients. ( Chrysant, SG; Fox, AA; Stimpel, M, 1995)
"The effect of calcium channel blocker (CCB), amlodipine (5-10 mg/day) and angiotensin-converting enzyme (ACE) inhibitor, quinapril (10-40 mg/day) on ambulatory blood pressure (ABP), rheological and platelet function in hypertension were compared in this randomised double-blind placebo-controlled cross-over study."5.08Comparison of amlodipine and quinapril on ambulatory blood pressure and platelet function in hypertension. ( Chang, SM; Chou, TC; Ding, YA, 1995)
"The effects on blood pressure (BP) and heart rate (HR), at rest and during bicycle exercise, of the vascular selective calcium antagonist felodipine, the cardio-selective beta-blocker metoprolol, and of the two drugs in combination, were assessed in a double-blind, three-way cross-over study comprising 23 patients with essential, mild to moderate hypertension."5.08Effects of felodipine, metoprolol and their combination on blood pressure at rest and during exercise and on volume regulatory hormones in hypertensive patients. ( Elmfeldt, DB; Gordon, RD; Klemm, SA; Tunny, TJ; Wicks, JR, 1995)
"In forty six hypertensive patients in whom a high level of clinical suspicion for renovascular hypertension was present on the basis of clinical clues, a captopril test was performed with either 25 mg of captopril or placebo on 2 separate days to determine prospectively the value of the captopril test."5.08'Captopril test', with blood pressure and peripheral renin as response variables in hypertensive patients with suspected renal artery stenosis. ( de Leeuw, PW; Lavrijssen, AT; Schiffers, PM; Schreij, G; van Es, PN, 1995)
"The effects of inhibition of the renin-angiotensin system with quinapril on adrenergic transmission were determined in 18 patients with moderate essential hypertension."5.08Quinapril ACE-inhibition effects on adrenergic parameters in moderate essential hypertension. ( Bronsoms Artero, J; Matas Serra, M; Matè Benito, G; Mauri Nicolas, JM; Torguet Escuder, P; Vallès Prats, M, 1996)
"This study compared the effects of 1 year of monotherapy with a calcium-channel antagonist (nilvadipine; NIL), an angiotensin-converting enzyme (ACE) inhibitor (temocapril; TEM), or a new vasodilator (cadralazine; CAD) on left ventricular (LV) hypertrophy in essential hypertension."5.08The effects of long-term treatment on left ventricular hypertrophy in patients with essential hypertension: relation to changes in neurohumoral factors. ( Inoue, H; Oh-hashi, S; Takata, M; Tomita, S; Ueno, H; Yasumoto, K, 1997)
" We administered angiotensin II in graded infusion doses to patients with primary hypertension and normotensive controls to study the effects of on circulating kallikreins."5.08Circulating plasma prekallikrein and tissue kallikrein in normotensive and hypertensive humans: effects of angiotensin II infusion. ( Karlberg, BE; Ohman, KP, 1998)
"We investigated whether rampiril has selective effects on autonomic control of the circulation in human hypertension, compared with the more hydrophilic ACE inhibitor enalapril."5.07Does lipophilicity of angiotensin converting enzyme inhibitors selectively influence autonomic neural function in human hypertension? ( Cervenka, JH; Kailasam, MT; Kennedy, BP; O'Connor, DT; Parmer, RJ; Wu, RA; Ziegler, MG, 1994)
"The effects of two types of angiotensin converting enzyme (ACE) inhibitors, enalapril (long-acting) and captopril (short-acting), on serum electrolytes and circadian rhythm of urinary electrolyte excretions were compared in relation to aldosterone status in patients with essential hypertension and normal renal function."5.07Crossover comparison of the effects of enalapril and captopril on potassium homeostasis in patients with mild hypertension. ( Abe, I; Fujishima, M; Kobayashi, K; Ohmori, S; Ohya, Y; Takata, Y; Tominaga, M; Ueno, M, 1994)
"Eight normotensive subjects, eight mild-to-moderate hypertensive type II diabetic patients, and eight nondiabetic patients with essential hypertension were studied before and after 4 weeks of being administered enalapril."5.07Enhanced pressor responsiveness to norepinephrine in type II diabetes. Effect of ACE inhibition. ( Capelli, M; Ciavarella, A; Mustacchio, A; Ricci, C; Vannini, P, 1994)
"The present study was performed to clarify changes in plasma levels of 19-hydroxyandrostenedione (19-OH-AD), an amplifier of aldosterone and a possible hypertensinogenic steroid, during several tests for the renin-angiotensin system in 20 patients with aldosterone-producing adenoma (APA) and to determine whether 19-OH-AD participates in the etiology of the hypertension in this disorder."5.07Low plasma 19-hydroxyandrostenedione levels in patients with aldosterone-producing adenoma. ( Miura, K; Miyazaki, S; Morita, H; Mune, T; Yamakita, N; Yasuda, K, 1993)
"The authors assessed in 20 subjects with mild or medium severe arterial hypertension basal and stimulated values of plasma renin activity (PRA) and aldosterone before onset of treatment and after 6-week therapy with enalapril (ENAP KRKA) or metoprolol (Vasocardin Slovakofarma)."5.07[The importance of studying the renin-angiotensin-aldosterone system in essential arterial hypertension in clinical practice. Activity of the renin-angiotensin-aldosterone system during treatment of hypertension with ACE-inhibitors and beta blockers]. ( Chamulová, M; Hrnciar, J; Hrnciarová, M; Kreze, A; Lepej, J; Okálová, D, 1994)
" 10 with mild uncomplicated and untreated essential hypertension, 10 with essential hypertension under chronic treatment with captopril, 50 mg bid, and 10 with essential hypertension under chronic treatment with atenolol, 100 mg oid, received aspirin, 100 mg oid, and the corresponding placebo for one month, according to a double blind randomized cross-over design."5.07Hemodynamic and humoral effects of low-dose aspirin in treated and untreated essential hypertensive patients. ( Abdel-Haq, B; Favilla, S; Magagna, A; Salvetti, A; Taddei, S, 1994)
"Ketanserin, a serotonin-2-receptor antagonist, was administered to 16 patients with mild to moderate essential hypertension in randomized single-blind placebo controlled study."5.07[Influence of chronic ketanserin therapy on blood pressure and certain humoral and metabolic factors in patients with mild to moderate primary essential hypertension]. ( Berent, H; Brym, E; Czerniewska, E; Januszewicz, W; Knypl, K; Kuçzyńska, K; Wacławek-Maczkowska, J; Wasowska, T; Wocial, B, 1993)
"The effect of three calcium entry blockers--verapamil, nifedipine and felodipine--on diuresis, natriuresis, the renin-aldosterone axis, and atrial natriuretic peptide (ANP) levels was studied in 30 previously untreated patients with mild to moderate essential hypertension."5.07The role of atrial natriuretic peptide in the diuretic effect of Ca2+ entry blockers. ( Ezra, D; Peleg, E; Rosenthal, T; Shamiss, A, 1993)
" After a two-week, placebo run-in phase, 110 patients with mild to moderate hypertension were randomised to receive 10 mg lisinopril or enalapril, or placebo for 4 weeks."5.07Twenty-four hour blood pressure effect of once-daily lisinopril, enalapril, and placebo in patients with mild to moderate hypertension. ( Dunne, B; Glazer, N; Kostis, JB; Miller, WE; Rector, DJ; Tresznewsky, ON; Whelton, A, 1992)
" Nine outpatients with mild and moderate hypertension were studied in the Cardiology Service of Vargas Hospital with a D1 agonist, piribedil, at 50-100 mg/day, orally, for 8 weeks, and with a D2 agonist, bromocriptine, at 2."5.07Comparative effects of dopaminergic agonists on cardiovascular, renal, and renin-angiotensin systems in hypertensive patients. ( Alvarez, R; Luchsinger, A; Morillo, J; Pieretti, OH; Romero, E; Urbina, A; Velasco, M, 1992)
"The effects of a sustained-release formulation of the calcium antagonist nicardipine on left ventricular (LV) mass, Doppler transmitral velocity profiles and plasma neurohumoral studies were analyzed in patients with mild to moderate systemic hypertension."5.07Effects of sustained-release nicardipine on regression of left ventricular hypertrophy in systemic hypertension. ( Adler, J; Dittrich, HC; Ong, J; Reitman, M; Weber, M; Ziegler, M, 1992)
"The short-term effects of atenolol and nifedipine on plasma levels of atrial natriuretic peptide (ANP), plasma renin activity (PRA), and plasma aldosterone (PA) were studied in two groups of patients with uncomplicated essential hypertension."5.07Short-term effects of atenolol and nifedipine on atrial natriuretic peptide, plasma renin activity, and plasma aldosterone in patients with essential hypertension. ( Bucci, V; Casale, R; Colantonio, D; Desiati, P; Giandomenico, G; Pasqualetti, P, 1991)
"Nifedipine causes an acute and a sustained reduction in sodium balance in patients with essential hypertension."5.07Acute and sustained changes in sodium balance during nifedipine treatment in essential hypertension. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR, 1991)
"11 inhibitor candoxatril in eight patients with untreated essential hypertension on high sodium (350 mmol/day) and low sodium (10 mmol/day) diets."5.07Dietary sodium and inhibition of neutral endopeptidase 24.11 in essential hypertension. ( Buckley, MG; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR, 1991)
"A randomized, double-blind, placebo-controlled study was conducted to study the effects of acute and chronic administration of carvedilol in essential hypertension, with special emphasis on renal haemodynamics and function."5.06Effects of carvedilol on renal function. ( Dupont, AG, 1990)
"In a double-blind 6 month trial, the cardiac effects of captopril and minoxidil, administered as third step treatments, were compared in 34 men with essential hypertension and diastolic blood pressure greater than 95 mm Hg who were taking 200 mg/day of metoprolol and 80 mg/day of furosemide."5.06Effects of captopril and minoxidil on left ventricular hypertrophy in resistant hypertensive patients: a 6 month double-blind comparison. ( Chatellier, G; Corvol, P; Dufloux, MA; Julien, J; Menard, D; Menard, J; Plouin, PF; Prasquier, R, 1990)
"The effects of 6 weeks of treatment with dilevalol 100 mg once daily, or carteolol 10 mg once daily, on renal blood flow (RBF), glomerular filtration rate (GFR) and total renal vascular resistance (TRR) were studied in 10 patients with mild-to-moderate essential hypertension in a randomised cross-over experiment."5.06Comparison of the renal effects of dilevalol and carteolol in patients with mild to moderate essential hypertension. ( Baba, T; Murabayashi, S; Takebe, K; Tomiyama, T, 1990)
"The renal, metabolic and antihypertensive effects of enalapril (E) and slow-release verapamil (V) were compared in a 2-month double-blind crossover trial in 22 patients with newly discovered essential hypertension."5.06Antihypertensive and renal effects of enalapril and slow-release verapamil in essential hypertension. A double-blind, randomized study. ( Fagher, B; Henningsen, N; Hulthén, L; Katzman, P; Thulin, T, 1990)
"The purpose of the study was to evaluate the effects of a dihydropyridine calcium antagonist, nicardipine (N), on blood pressure (BP) and aldosterone secretion in hypertensive patients (pt) with primary aldosteronism."5.06[Effect of a calcium inhibitor, nicardipine, on aldosterone secretion in primary hyperaldosteronism]. ( Begasse, F; Chamontin, B; David, D; Salvador, M, 1989)
"The effects of acute calcium entry blockade by isradipine (IS) and placebo (P) on the haemodynamic and humoral responses to angiotensin II (A II) have been compared in two groups of 9 patients with essential hypertension."5.06Acute calcium entry blockade inhibits the blood pressure but not the hormonal responses to angiotensin II. ( Amery, A; Fagard, R; Hespel, P; Lijnen, P; Moerman, E; Staessen, J, 1989)
"The chronic effect of the calcium antagonist nitrendipine was investigated on blood pressure (BP), plasma aldosterone concentration (PAC), plasma renin activity (PRA), and serum potassium in six patients with primary aldosteronism, either due to an (unilateral) aldosterone-producing adenoma (APA; n = 3; age, 44 +/- 4 years; PAC, 312 +/- 96 pg/ml; PRA, less than 0."5.06Therapeutic value of calcium antagonists in autonomous hyperaldosteronism. ( Ivens, K; Kaufmann, W; Stimpel, M; Volkmann, HP; Wambach, G, 1989)
" To investigate the contribution of sedation to the cardiovascular effects induced by clonidine, we studied patients with essential hypertension on two separate occasions when similar levels of sedation were induced by clonidine and nitrazepam."5.06The haemodynamic and hormonal responses after clonidine occur independently of sedation in essential hypertension. ( Kooner, JS; Mathias, CJ; Peart, WS, 1989)
"To investigate the pathogenetic constellation and its modification by calcium channel blockade in hypertension associated with chronic nonoliguric renal failure, blood pressure (BP), various pressor factors or correlates, cardiovascular responsiveness, and plasma atrial natriuretic peptide (ANP) were assessed in 15 hypertensive patients (serum creatinine 160-715 mumol/l) before and after 6 weeks of intervention with the agent nitrendipine."5.06Hypertensive dysregulation and its modification by calcium channel blockade in nonoliguric renal failure. ( Bürgisser, E; Ferrier, C; Gnädinger, MP; Jahn, H; Schohn, D; Weidmann, P, 1989)
"This double-blind placebo controlled study investigated the antihypertensive and humoral effects of nifedipine capsules in patients with essential hypertension inadequately controlled (seated diastolic blood pressure greater than or equal to 95 mm Hg) by hydrochlorothiazide (HCTZ) alone."5.06Antihypertensive and humoral effects of nifedipine in essential hypertension uncontrolled by hydrochlorothiazide alone. ( Abraham, PA; Halstenson, CE; Opsahl, JA, 1989)
"The effects of enalapril alone and in combination with the cyclooxygenase inhibitors sulindac and indomethacin on blood pressure (BP), plasma aldosterone, renin activity and converting enzyme activity were evaluated in 29 patients with mild to moderate essential hypertension, 26 of whom had low plasma renin activity."5.06Antihypertensive effect of enalapril in essential hypertension: role of prostacyclin. ( Hammett, DK; Horton, R; Irvin, J; Oparil, S; Wilkins, LH, 1987)
"Phenylephrine infusions enhance diuresis and natriuresis both in normal subjects and patients with essential hypertension, whereas they have an opposite effect on urinary aldosterone excretion, decreasing it in normal subjects and enhancing it in hypertensive patients."5.06[Effects of phenylephrine on atrial natriuretic factor and the renin-aldosterone axis in normal patients and essential hypertensive patients]. ( Cantin, M; Closas, J; Cusson, J; De Léan, A; Genest, J; Gutkowska, J; Hamet, P; Larochelle, P; Thibault, G, 1988)
"A series of studies were undertaken to assess the effect of oral fenoldopam, a specific DA1 dopamine receptor agonist on blood pressure and renal function in patients with mild essential hypertension."5.06Studies with fenoldopam, a dopamine receptor DA1 agonist, in essential hypertension. ( Brown, J; Harvey, JN; Lee, MR; Worth, DP, 1986)
"In order to evaluate the acute effects of urapidil on renal vascular tone and on pressor systems we performed a randomised placebo-controlled crossover study in 8 patients with uncomplicated essential hypertension."5.06Renal haemodynamic and neurohumoral responses to urapidil in hypertensive man. ( Birkenhäger, WH; de Bruyn, HA; de Leeuw, PW; van Es, PN, 1988)
"A randomized crossover trial was conducted in 15 patients with essential hypertension to compare the actions of prazosin, a specific alpha 1-adrenoceptor blocker, and ketanserin, an antagonist at alpha 1-adrenergic and serotonin receptors."5.06Ketanserin and prazosin: a comparison of antihypertensive and biochemical effects. ( Marwood, JF; Mennie, BA; Stokes, GS, 1986)
"To evaluate the humoral and hemodynamic (both systemic and renal) effects of celiprolol and to assess whether these effects are at least partially due to the activation of dopamine (DA) receptors, 9 out-patients with mild to moderate uncomplicated essential hypertension, without any therapy for at least 3 weeks, received celiprolol (400 mg once daily) and placebo, each for 1 month, according to a double-blind randomized trial pattern."5.06Systemic and renal hemodynamic effects of celiprolol in essential hypertensives. ( Lucarini, AR; Salvetti, A, 1988)
"Twenty-seven subjects with essential hypertension were prospectively followed for a minimum of 100 weeks, receiving either enalapril monotherapy or enalapril and hydrochlorothiazide combination therapy."5.06Humoral effects of long-term oral enalapril therapy. ( Bauer, JH; Reams, GP, 1986)
"The effect of chronic converting enzyme inhibition with enalapril on the PRA, PRL and plasma aldosterone responses to metoclopramide was studied in 10 patients with mild to moderate essential hypertension."5.06Enhanced response of plasma prolactin to metoclopramide during chronic converting enzyme inhibition. ( Dupont, AG; Van der Nipen, P; Van Steirteghem, AC; Vanhaelst, L, 1987)
"The antihypertensive effects of the 5-HT2 receptor antagonist ketanserin were evaluated in 16 patients with uncomplicated essential hypertension."5.06Antihypertensive response to ketanserin: influence of race and weight. ( Cressman, MD; Ferguson, RK; Gabos, C; Kosoglou, T; Rocci, ML; Vlasses, PH, 1988)
"The effects of the addition of a calcium entry antagonist, nifedipine (20-mg tablet twice a day), to an angiotensin converting enzyme inhibitor, captopril (25 mg three times a day), and the addition of captopril to nifedipine were observed in two separate studies in patients with essential hypertension."5.06Captopril and nifedipine in combination for moderate to severe essential hypertension. ( MacGregor, GA; Markandu, ND; Shore, AC; Singer, DR, 1987)
" To investigate this, 75 out-patients with essential hypertension were treated with chlorthalidone 12."5.06Plasma renin activity does not predict the antihypertensive efficacy of chlorthalidone. ( Bartolomei, G; Cagianelli, MA; Cinotti, G; Innocenti, P; Loni, C; Papi, L; Pedrinelli, R; Saba, G; Saba, P; Salvetti, A, 1987)
" In nine patients with essential hypertension, following single and multiple doses of ketanserin, assessments were made of blood pressure and heart rate, QT interval, and pressor responses to phenylephrine and angiotensin II."5.06Acute and chronic ketanserin in essential hypertension: antihypertensive mechanisms and pharmacokinetics. ( Donnelly, R; Elliott, HL; Meredith, PA; Reid, JL, 1987)
"After a run-in period of 8 weeks on a regimen of hydrochlorothiazide (HCT, median dosage 75 mg/day), patients with essential hypertension were randomly allocated to continued hydrochlorothiazide therapy (Group I) or additional treatment with amiloride (Group II, median dosage 15 mg/day, or 5 mg per 25 mg hydrochlorothiazide) for the following 12 weeks."5.06Effects of combined therapy with amiloride and hydrochlorothiazide on plasma and total body potassium, blood pressure, and the renin-angiotensin-aldosterone system in hypertensive patients. ( Dige-Petersen, H; Giese, J; Ibsen, H; Leth, A; Nielsen, MD; Rasmussen, S; Svendsen, UG, 1986)
"In order to assess the neurohormonal responses to oral administration of two drugs with different antihypertensive mechanisms, and their implications for long-term efficacy, we studied the changes in plasma renin activity, aldosterone, catecholamines and blood pressure after two cross-over periods of treatment with captopril and hydrochlorothiazide for three months in 14 patients with moderate essential hypertension."5.06Neurohormonal responses to antihypertensive treatment with captopril or hydrochlorothiazide. ( Balcells, A; Gaya, J; Ingelmo, M; Rabinad, E; Rivera, F, 1986)
"In an open triple crossover study in 8 patients with essential hypertension, the possibility has been investigated of whether the blood pressure lowering effect of hydrochlorothiazide 50 mg once daily was attenuated by co-administration for 4 weeks of ibuprofen 400 mg t."5.06The influence of ibuprofen, diclofenac and sulindac on the blood pressure lowering effect of hydrochlorothiazide. ( Gribnau, FW; Koopmans, PP; Thien, T, 1987)
"Blood pressure (BP), plasma electrolytes, renin, aldosterone, angiotensin II (AII) or catecholamines, the chronotropic effects of intravenous isoproterenol, norepinephrine (NE) or AII, the pressor responses to NE or AII, and the relationship between plasma AII and aldosterone concentrations were studied before and after 10 days of dietary supplementation with potassium 100 mmol/day, in normotensive members of normotensive (N = 12) or hypertensive (N = 12) families, and 11 patients with borderline essential hypertension."5.06Potassium and norepinephrine- or angiotensin-mediated pressor control in pre-hypertension. ( Beretta-Piccoli, C; Bianchetti, MG; Ferrier, C; Weidmann, P, 1987)
"The efficacy and tolerability of the new ACE-inhibitor enalapril (MK 421) and the beta 1-selective adrenoceptor blocker atenolol for the treatment of primary hypertension were compared in a double blind parallel study."5.05Enalapril and atenolol in primary hypertension--a comparative study of blood pressure lowering and hormonal effects. ( Karlberg, BE; Ohman, KP, 1984)
"The hormonal and hypotensive effects of a single oral 10 mg dose of enalapril (MK-421), were assessed by a double-blind randomized trial in 12 subjects with essential hypertension, during a 100 and 40 mmol/day sodium intake."5.05Effect of dietary sodium on angiotensin-converting enzyme (ACE) inhibition and the acute hypotensive effect of enalapril (MK-421) in essential hypertension. ( Cubela, R; Jackson, B; Johnston, CI, 1984)
"The possibility of beta-adrenoreceptor hypersensitivity after abrupt withdrawal of long-term therapy (8-18 months) with the slow-release (SR) formulation of oxprenolol (160-320 mg/day) was assessed in six patients with uncomplicated essential hypertension."5.05Lack of beta-adrenoreceptor hypersensitivity after abrupt withdrawal of long-term therapy with oxprenolol. ( Amann, FW; Bolli, P; Bühler, FR; Burckhardt, D; Meier, M; Raeder, EA; Rogg, H, 1981)
" In 14 patients with mild to moderate essential hypertension, the effects of bucindolol, hydrochlorothiazide and their combination on blood pressure (BP), heart rate (HR) and parameters of the renin-aldosterone system were compared with those after placebo."5.05Bucindolol, a beta-adrenoceptor blocker with vasodilatory action: its effect in systemic hypertension. ( Fedder, IL; Ferguson, RK; Rocci, ML; Rotmensch, HH; Soyka, L; Swanson, BN; Vlasses, PH, 1984)
"The aim of this study was to investigate and compare the effects of two calcium antagonist drugs, verapamil (VER) and nifedipine (NIF), on blood pressure (BP), heart rate (HR), plasma catecholamines (pCA), renin (PRA), plasma aldosterone (pALD), and plasma volume (PV) in a group of patients with mild to moderate essential hypertension."5.05Antihypertensive and humoral effects of verapamil and nifedipine in essential hypertension. ( Agabiti-Rosei, E; Alicandri, CL; Beschi, M; Castellano, M; Corea, L; Fariello, R; Muiesan, G; Romanelli, G, 1982)
"The effect of low doses (25 mg three times a day) of captopril was evaluated in 16 patients with mild to moderate essential hypertension, previously uncontrolled by hydrochlorothiazide."5.05Low-dose captopril: its use in mild to moderate hypertension unresponsive to diuretic treatment. ( Ferguson, RK; Mojaverian, P; Rotmensch, HH; Swanson, BN; Vlasses, PH, 1982)
"Eight patients with essential hypertension completed a double-blind, randomly allocated crossover comparison of either 5 or 10 mg enalapril maleate, 50 mg hydrochlorothiazide, or their combination administered once daily during sequential two-week periods."5.05A comparative pilot study of enalapril, a new converting enzyme inhibitor, and hydrochlorothiazide in essential hypertension. ( Ferguson, RK; Irvin, JD; Lee, RB; Swanson, BN; Vlasses, PH, 1982)
"The effects of captopril and propranolol on blood pressure, heart rate and plasma noradrenaline, renin and aldosterone, and on the responses to changes in posture and to isometric exercise were measured in patients with essential hypertension."5.05The effect of captopril and propranolol on the responses to posture and isometric exercise in patients with essential hypertension. ( Goodwin, FJ; Holly, JM; Marsh, FP; Sharman, VL; Vandenburg, MJ, 1983)
"57 years), with primary arterial hypertension, was submitted to two periods of treatment in a cross-over study with spironolactone and potassium canrenoate."5.05[Clinical study of the efficacy of oral potassium canrenoate and spironolactone in essential arterial hypertension]. ( Fanti, P; Mantellini, R; Sciarra, F; Tosti-Croce, C, 1983)
"The effects on blood pressure, the renin-angiotensin-aldosterone and the kallikrein-kinin systems were investigated in 32 patients with primary hypertension WHO stage I-II treated with captopril."5.05Captopril, aldosterone and urinary kallikrein in primary hypertension. ( Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S, 1983)
"The metabolic effects of piretanide (2 x 6 mg daily) were compared with those of hydrochlorothiazide, in doses of 2 x 25 mg or 2 x 50 mg daily, in a double-blind study consisting of three parallel groups totalling 15 patients with uncomplicated essential hypertension."5.05The effects of piretanide on catecholamine metabolism, plasma renin activity and serum aldosterone: a double-blind pilot comparison against hydrochlorothiazide in patients with essential hypertension. ( Bückert, C; Kirsten, R; Verho, M, 1984)
"Thirty-two patients with moderate to severe essential hypertension whose supine diastolic blood pressure (SDBP) was greater than or equal to 95 mm Hg following 2 weeks' treatment with the optimal dosage of beta blocker-diuretic combination were randomly assigned to the addition of either captopril 25 mg or 50 mg b."5.05Efficacy of low-dose captopril given twice daily to patients with essential hypertension uncontrolled by a beta blocker plus thiazide diuretic. ( Agabiti-Rosei, E; Alicandri, C; Boni, E; Cinquegrana, A; Fariello, R; Montini, E; Muiesan, G; Muiesan, ML; Zaninelli, A, 1984)
"Thirty-two patients with primary hypertension were studied in a double-blind cross-over comparison between the cardioselective beta 1-blocking agent atenolol and the combined alpha- and beta-blocking agent labetalol."5.05Antihypertensive and metabolic effects of increasing doses of atenolol and labetalol. A comparative study in primary hypertension. ( Henningsen, NC; Karlberg, BE; Nilsson, OR; Thulin, T, 1982)
"Twenty-four patients with moderate to severe hypertension were treated for four weeks with captopril, an oral inhibitor of angiotensin-converting enzyme."5.05Captopril in essential hypertension; contrasting effects of adding hydrochlorothiazide or propranolol. ( Banks, RA; Bayliss, J; Jones, JC; MacGregor, GA; Markandu, ND; Roulston, JE, 1982)
"The effects of amiloride hydrochloride on thiazide-induced hypokalemia were evaluated."5.05Response of thiazide-induced hypokalemia to amiloride. ( Chan, L; Maronde, RF; Milgrom, M; Vlachakis, ND, 1983)
"Blood pressure, cardiac output, plasma volume, renin, and aldosterone were measured in 13 patients with essential hypertension on placebo and after 1, 4, and 12 wk on hydrochlorothiazide 100 mg daily."5.05Hemodynamic changes during long-term thiazide treatment of essential hypertension in responders and nonresponders. ( Man in 't Veld, AJ; Schalekamp, MA; van Brummelen, P, 1980)
"The magnitude and duration of the antihypertensive effect of nifedipine were studied in 7 cases of moderate essential hypertension."5.05Antihypertensive effect of fractionated sublingual administration of nifedipine in moderate essential hypertension. ( Bonnet, F; Corvol, P; Thibonnier, M, 1980)
"Captopril (SQ 14 225), an orally active inhibitor of angiotensin converting enzyme, was evaluated in the treatment of primary (essential) hypertension in a placebo-controlled long-term study."5.05Captopril, an orally active converting enzyme inhibitor, in the treatment of primary hypertension. A controlled long-term study with reference to initial plasma renin activity. ( Asplund, J; Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S, 1981)
"In a single-dose crossover study Captopril (SQ 14225), 1 mg/kg body weight, and Nifedipine (Bay a 1040) 20 mg were administered orally to 12 hospitalized patients with essential hypertension (Stage 1 or 2, W."5.05Antihypertensive and hormonal effects of single oral doses of captopril and nifedipine in essential hypertension. ( Corvol, P; Menard, J; Milliez, P; Sire, O; Soto, ME; Thibonnier, M, 1981)
"Thirty patients with mild or moderate essential hypertension, and a fixed elevation of diastolic blood pressure, were randomly allocated to three groups and treated with propranolol 40 mg x 4 (Group 1), 80 mg x 4 (group 2) and 160 mg x 4 (Group 3)."5.05Correlation between propranolol in plasma and urine, renin-aldosterone system and blood pressure in essential hypertension. ( Andreasen, F; Bjerregaard, P; Kornerup, HJ; Pedersen, EB; Pedersen, OL, 1981)
"In a double-blind crossover study, the antihypertensive effect of hydrochlorothiazide alone and in combination with the beta blocker acebutolol was assessed in 18 patients suffering from mild to moderate hypertension."5.05Merits of adding a beta blocker (acebutolol) to a diuretic (hydrochlorothiazide) in the treatment of hypertension. ( Belleau, LJ; Brossard, JJ; Lebel, M, 1982)
"Sixteen patients with essential hypertension completed a double blind factorial trial comparing the effects of indapamide (2."5.05Effects of once daily indapamide and pindolol on blood pressure, plasma aldosterone concentration and plasma renin activity in a general practice setting. ( Bune, AJ; Chalmers, JP; Graham, JR; Grygiel, JJ; West, MJ; Wing, LM, 1982)
"A double-blind, cross-over study in 16 patients with essential hypertension was carried out, to evaluate any possible interference by indomethacin, a known prostaglandin-synthetase inhibitor, with the antihypertensive effect of oxprenolol, a non-selective beta-adrenoceptor blocking agent."5.05Interaction between oxprenolol and indomethacin on blood pressure in essential hypertensive patients. ( Arzilli, F; Beggi, P; Motolese, M; Pedrinelli, R; Salvetti, A, 1982)
" Since ketanserin, a more specific 5-HT2-serotoninergic (5-HT2) antagonist, has been shown to affect aldosterone secretion in essential hypertension, we have further investigated this mechanism by injecting ketanserin (10 mg i."5.05Effect of ketanserin in primary aldosteronism. ( Armanini, D; Boscaro, M; D'Agostino, D; Mantero, F; Opocher, G; Rocco, S, 1985)
"To determine if food reduces the hemodynamic and humoral effects of captopril in patients with essential hypertension, we performed two studies."5.05Influence of food on acute and chronic effects of captopril in essential hypertensive patients. ( Abdel-Haq, B; Graziadei, L; Magagna, A; Pedrinelli, R; Salvetti, A; Stornello, M; Taddei, S, 1985)
" To assess the effect of potassium repletion in hypokalemic hypertension, we administered either potassium chloride, 60 mmol per day, or placebo tablets, each for six weeks, in a randomized, double-blind, crossover trial to 16 hypertensive patients who had diuretic-induced hypokalemia and who continued to take a constant amount of diuretic."5.05Potassium supplementation in hypertensive patients with diuretic-induced hypokalemia. ( Carnegie, A; Heller, JA; Kaplan, NM; Raskin, P; Simmons, M, 1985)
"To determine the effects of potassium on blood pressure and factors affecting blood pressure, we conducted a randomized, placebo controlled trial of a potassium chloride-based substitute for table salt in 23 patients with mild to moderate essential hypertension."5.05Effects of potassium on sodium balance, renin, noradrenaline and arterial pressure. ( Barnett, P; Cumming, AM; Hutcheson, MJ; Semple, PF; Zoccali, C, 1985)
"Renal plasma flow, glomerular filtration rate plasma angiotensin II, aldosterone and arginine vasopressin, free water clearance, blood pressure and body weight in 11 patients with mild to moderate hypertension were determined at the end of consecutive 6 week periods of administration of placebo and verapamil up to 120 mg t."5.05Effect of verapamil on renal plasma flow, glomerular filtration rate and plasma angiotensin II, aldosterone and arginine vasopressin in essential hypertension. ( Danielsen, H; Pedersen, EB; Sørensen, SS; Thomsen, OO, 1985)
"Effect of long-term administration of propranolol was studied in 90 unselected patients with essential hypertension."5.04[Treatment of essential hypertension with propranolol (author's transl)]. ( Braun, B; Klaus, D; Klumpp, F; Lemke, R; Zehner, J, 1976)
" Captopril was shown to be as effective as hydrochlorothiazide in lowering the blood pressure in patients with moderately severe essential hypertension."5.04Hormonal changes with long-term converting-enzyme inhibition by captopril in essential hypertension. ( Johnston, CI; Matthews, PG; McGrath, BP, 1979)
"Eighteen patients with diastolic hypertension (100 to 120 mm Hg), in addition to propranolol, 160 mg daily, and hydrochlorothiazide, 100 mg daily, received progressively increased doses of either minoxidil or placebo in a double-blind crossover study."5.04Effect of minoxidil on blood pressure and hemodynamics in severe hypertension. ( Bryan, RK; Hoobler, SW; Purdy, JM; Rosenzweig, J; Weller, JM, 1977)
"A double-blind study of hydrochlorothiazide and spironolactone, alone and in combination, was conducted in 49 patients with mild-to-moderate essential hypertension after a 4-wk placebo washout period."5.04Hydrochlorothiazide and spironolactone in hypertension. ( Schrijver, G; Weinberger, MH, 1979)
" Plasma renin activity (PRA), the daily urinary excretion of aldosterone (dU-Aldo) and electrolytes were studied before and during dihydralazine therapy (25 mg 3 times daily)."5.04The renin-aldosterone system in dihydralazine therapy during hypertensive pregnancy. ( Lammintausta, R, 1978)
"The antihypertensive effect of the selective beta-1-adrenoceptor blocker, metoprolol, administered once daily was evaluated in 32 patients with primary hypertension."5.04Once-daily metoprolol in primary hypertension. ( Karlberg, BE; Nilsson, O; Nitelius, E; Tolagen, K; Waern, U, 1979)
" Four different doses of labetalol (150, 300, 600 and 900 mg/day) were given for 1 week to each of four groups of patients with essential hypertension (six patients for each group)."5.04Effect of increasing doses of labetalol on blood pressure, plasma renin activity and aldosterone in hypertensive patients. ( Arzilli, F; Pedrinelli, R; Salvetti, A; Sassano, P, 1979)
"15 patients who had benign, uncomplicated essential hypertension, were treated with chlorthiazide (500 mg twice a day) with or without propranolol (10--20 mg 4 times a day), and the effect of the treatment on plasma renin activity (PRA), urinary aldosterone excretion, total body potassium (TBK) and plasma sodium and potassium was evaluated."5.04The renin-aldosterone system and thiazide-induced depletion of total body potassium in essential hypertension. ( Carroll, HJ; Oh, MS, 1978)
" Serial measurements of plasma renin activity (PRA), plasma aldosterone concentration (PA) and blood pressure were performed overnight in patients with borderline (group 1) and sustained essential hypertension (group 2) before and after acute and chronic administration of either propranolol or pindolol."5.04Differential effects of acute and chronic beta-adrenoreceptor blockade on blood pressure and the renin-angiotensin-aldosterone system in essential hypertension. ( Gramann, W; Kolloch, R; Krück, F; Stumpe, KO; Vetter, H, 1976)
"Furosemide and the prostaglandin synthetase inhibitor, indomethacin, were administered singly and in combination to four normal subjects and six patients with essential hypertension in order to determine whether the antihypertensive, natriuretic and other effects of furosemide could be altered by inhibition of prostaglandin synthesis."5.04Antagonism of the effects of furosemide by indomethacin in normal and hypertensive man. ( Babej, M; Bentzel, CJ; Hysert, PE; Lee, JB; Mookerjee, BK; Patak, RV, 1975)
"To review comparative efficacy and tolerability data between the two main mineralocorticoid receptor antagonists (MRAs), spironolactone and eplerenone, in patients with resistant hypertension (HTN)."5.01Eplerenone Versus Spironolactone in Resistant Hypertension: an Efficacy and/or Cost or Just a Men's Issue? ( Manolis, AA; Manolis, AS; Manolis, TA; Melita, H, 2019)
" Diagnosis relies on a triad of hypertension, hypokalemia and suppressed plasma aldosterone levels, plus an abnormal urinary cortisol to cortisone ratio, either free steroid or metabolites."4.95Apparent mineralocorticoid excess. ( Funder, JW, 2017)
"Animal studies point to a small increase in plasma and cerebrospinal fluid (CSF) [Na], a small decrease in CSF [K], and increased levels of circulating angiotensin II, aldosterone, and endogenous ouabain as the central signals evoking hypertension."4.95Sodium and potassium in the pathogenesis of hypertension: focus on the brain. ( Adrogué, HJ; Madias, NE, 2017)
" It will consider the relationship between obesity and leptin resistance and sympathetic signaling; the role of obstructive sleep apnea in resistant hypertension; and the role of aldosterone in resistant hypertension."4.90Resistant hypertension in diabetes mellitus. ( Bayliss, G; D'Elia, JA; Weinrauch, LA, 2014)
" Angiotensin II and aldosterone often collaborate in pathological situations to induce hypertrophy of cardiomyocytes, vascular inflammation, perivascular and interstitial fibrosis, and microvascular rarefaction."4.89Aldosterone mediates cardiac fibrosis in the setting of hypertension. ( Azibani, F; Chatziantoniou, C; Delcayre, C; Fazal, L; Samuel, JL, 2013)
"(2) In RALES, low-dose spironolactone in addition to standard of care, produced a 30% improvement in survival in progressive heart failure, commonly assumed to reflect deleterious effects of aldosterone, with spironolactone competing with aldosterone for cardiac mineralocorticoid receptors."4.86Aldosterone, hypertension and heart failure: insights from clinical trials. ( Funder, JW, 2010)
" Angiotensin II, the principal effector peptide of the RAAS, has far-reaching effects on vascular structure, growth and fibrosis, and is a key regulator of vascular remodeling and inflammation."4.83Role of the renin-angiotensin-aldosterone system in vascular remodeling and inflammation: a clinical review. ( Duprez, DA, 2006)
" However, although aldosterone receptor antagonism reduces mortality in patients with congestive heart failure, the progestational and antiandrogenic side effects of the nonspecific aldosterone receptor antagonist, spironolactone, have limited its usefulness in the treatment of hypertension."4.82Eplerenone: cardiovascular protection. ( Brown, NJ, 2003)
"The pathogenic role of angiotensin II (ANG II), dietary sodium chloride, sympathetic activation, obesity and aldosterone in the development of structural vascular changes (SVCs) in hypertension is considered from three perspectives (criteria): their utility in predicting hypertension and its complications (predictability); the effect of their inhibition or removal on the reversal of SVCs (reversibility); and their ability to induce SVCs in experimental animals (reproducibility)."4.82Pathogenesis of structural vascular changes in hypertension. ( Simon, G, 2004)
" The selective aldosterone blocker, eplerenone (Inspra), is under development for human therapeutic use for treatment of hypertension and heart failure post-myocardial infarction (MI)."4.82Aldosterone target organ protection by eplerenone. ( McMahon, EG; Rocha, R; Rudolph, AE, 2004)
" Spironolactone and eplerenone are the mineralocorticoid receptor (MR) antagonists currently available for the treatment of hypertension."4.82Mineralocorticoid receptor antagonists and hypertension: is there a rationale? ( Gumieniak, O; Williams, GH, 2004)
" This review summarizes the effects of vasopressin on Na+ transport mediated by the amiloride-sensitive epithelial sodium channel (ENaC) and the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel in immortalized or primary cultured cortical collecting duct cells, expressing either the wild-type ENaC subunits, or mutations, or deletions of the PY domain of the beta- or gamma-ENaC subunits responsible for Liddle's syndrome, an inherited form of hypertension due to excessive salt absorption."4.82[Regulation by vasopressin of NaCl absorption in the renal collecting duct]. ( Vandewalle, A, 2005)
" The 30% improvement in mortality (and 35% in morbidity) seen in the RALES trial with the addition of low-dose spironolactone to best practice therapy in moderate to severe heart failure, similarly points to an unrecognized role for aldosterone in the pathophysiology of heart failure."4.81Mineralocorticoid receptors and pathophysiological roles for aldosterone in the cardiovascular system. ( Funder, JW; Young, MJ, 2002)
"In a 16-week study, eplerenone was more effective than placebo or losartan in lowering systolic blood pressure (BP) and diastolic BP in black patients with mild to moderate hypertension."4.81Clinical implications of aldosterone blockade. ( Weber, MA, 2002)
" The therapeutic efficacy of spironolactone (Pharmacia Corp) in severe chronic heart failure is established."4.81The role of aldosterone receptor blockade in the management of cardiovascular disease. ( Krum, H; Liew, D, 2002)
"Until recently, spironolactone was considered only as an antagonist at the aldosterone receptors of the epithelial cells of the kidney and was used clinically in the treatment of hyperaldosteronism and, occasionally, as a K(+)-sparing diuretic."4.81The spironolactone renaissance. ( Brown, L; Doggrell, SA, 2001)
" A provisional diagnosis of Liddle's syndrome was established and the patient was successfully treated with triamterene."4.80Liddle's syndrome in an elderly woman. ( Furukawa, K; Harada, T; Ikeda, S; Iwasaki, T; Kohno, S; Matsushita, M; Matsushita, T; Miyahara, Y; Miyazaki, M; Naito, T; Ogata, H; Ohzono, Y; Yakabe, K; Yamaguchi, K, 1998)
" Recent studies, however, have demonstrated that in several forms of chronic hypertension caused by aldosterone, angiotensin II (AngII), vasopressin, or norepinephrine and adrenocorticotropin, increased renal arterial pressure is essential for maintaining normal excretion of sodium and water in the face of reduced renal excretory capability."4.77Regulation of arterial pressure: role of pressure natriuresis and diuresis. ( Coleman, TG; Guyton, AC; Hall, JE; Mizelle, HL; Woods, LL, 1986)
"Only recently approved for use in the treatment of hypertension in the US, the beta-adrenergic receptor blocking compound propranolol has been used elsewhere for this purpose since 1964."4.75Pathophysiology of propranolol in hypertension. ( Frohlich, ED, 1977)
"The antihypertensive effect of intravenous (acute) and oral (long-term) beta-adrenergic blockade with propranolol or pindolol was evaluated in 46 male patients with either borderline (group I; 23 patients) or sustained (group II; 23 patients) essential hypertension."4.75Acute and long-term studies of the mechanisms of action of beta-blocking drugs in lowering blood pressure. ( Gramann, W; Higuchi, M; Kolloch, R; Krück, F; Ressel, C; Stumpe, KO; Vetter, H, 1976)
"Hydralazine, doxazosin, and verapamil are currently recommended by the Endocrine Society as acceptable bridging treatment in those in whom full cessation of antihypertensive medication is infeasible during screening for primary aldosteronism (PA)."4.31The Effects of Verapamil, Hydralazine, and Doxazosin on Renin, Aldosterone, and the Ratio Thereof. ( Alnazer, RM; de Leeuw, PW; Kroon, AA; Veldhuizen, GP, 2023)
" It has been reported that sPRR functions as an important regulator of intrarenal renin contributing to angiotensin II (ANG II)-induced hypertension."4.31Mutagenesis of the cleavage site of (pro)renin receptor abrogates aldosterone-salt-induced hypertension and renal injury in mice. ( Chen, Y; Fu, Z; Kaewsaro, K; Lambert, J; Yang, T; Zheng, H, 2023)
"The authors sought to determine the relationship of circulating angiotensinogen levels to ethnicity, sex, BP, incident hypertension, and prevalent hypertension in a modern sex-balanced ethnically diverse cohort."4.31Blood Levels of Angiotensinogen and Hypertension in the Multi-Ethnic Study of Atherosclerosis (MESA). ( Brambatti, M; Carlisle, SM; DeFilippis, AP; Kahlon, T; Michos, ED; Morgan, ES; Mostacero, DO; Mousavi, H; Mullick, AE; Ouyang, P; Shah, SJ; Tami, Y; Trainor, PJ; Tsimikas, S, 2023)
" In our study, we studied if continuous treatment with a mineralocorticoid receptor antagonist, spironolactone (30 mg/kg/day) for 20 days can: 1) attenuate hypertension development and restore inverted 24-h BP rhythm in hypertensive transgenic (mRen-2)27 rats (TGR) measured by telemetry; 2) improve function of the kidneys and heart; 3) be protective against high salt load (1% in water) by mitigating oxidative injury and improving kidney function."4.31Mineralocorticoid receptor blockade protects the kidneys but does not affect inverted blood pressure rhythm in hypertensive transgenic (mRen-2)27 rats. ( Kopkan, L; Majzunova, M; Molcan, L; Sutovska, H; Sykora, M; Zeman, M, 2023)
" The medical records of diabetic cats were searched for the keywords 'hypertension', 'blood pressure', 'amlodipine', 'benazepril' and 'telmisartan' to identify cats with SH, which was defined as systemic arterial blood pressure (SABP) ⩾160 mmHg, documented at least twice, over several days."4.31Concurrent disorders of cats with diabetes mellitus and arterial systolic hypertension. ( Hess, RS; Williams, JG, 2023)
"To study the development of microalbuminuria (MAU) in essential hypertension (EHT), we investigated the association of MAU with central blood pressure (CBP), direct renin concentration (DRC), plasma aldosterone (PA), and uric acid (UA)."4.31Central diastolic blood pressure, plasma aldosterone and uric acid are associated with microalbuminuria in essential hypertension: a case-control study. ( Chou, H; Li, J; Li, Y; Shi, L; Wei, M; Yang, N, 2023)
"Activity of the circulating renin-angiotensin-aldosterone system (RAAS) has not been comprehensively characterized in cats with systemic hypertension (SH) or cardiomyopathy (CM), and the effects of furosemide or amlodipine treatment on the RAAS have not been fully evaluated in cats."4.12Circulating renin-angiotensin-aldosterone system activity in cats with systemic hypertension or cardiomyopathy. ( Domenig, O; Guillot, E; Mochel, JP; Ward, JL; Ware, WA; Yuan, L, 2022)
"The saline suppression test (SST) and captopril challenge test (CCT) are commonly used confirmatory tests for primary aldosteronism (PA)."4.02Seated Saline Suppression Test Is Comparable With Captopril Challenge Test for the Diagnosis of Primary Aldosteronism: A Prospective Study. ( Cheng, Q; Du, Z; Feng, Z; He, W; Hu, J; Li, Q; Liu, B; Song, Y; Wang, Z; Xu, Z; Yang, J; Yang, S, 2021)
"We prospectively enrolled 121 patients with confirmed primary aldosteronism who started mineralocorticoid receptor antagonist (canrenone) treatment."4.02Mineralocorticoid Receptor Antagonist Effect on Aldosterone to Renin Ratio in Patients With Primary Aldosteronism. ( Avataneo, V; Bertello, C; Buffolo, F; Burrello, J; D'Avolio, A; Mengozzi, G; Monticone, S; Mulatero, P; Pecori, A; Rabbia, F; Rumbolo, F; Veglio, F, 2021)
"Recent reports described cases of severe hypertension and hypokalemia accompanied by low renin and aldosterone levels during antifungal therapy with posaconazole and itraconazole."3.96Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals. ( Beck, KR; Odermatt, A; Telisman, L; Thompson, GR; van Koppen, CJ, 2020)
"Vascular function, including reactive hyperemia index (RHI), flow-mediated vasodilation (FMD) and nitroglycerine-induced vasodilation (NID), arterial stiffness including brachial-ankle pulse wave velocity (baPWV) and brachial intima-media thickness (IMT) and ROCK activity in peripheral leukocytes were measured before and after 12 weeks of treatment with eplerenone in 50 patients with IHA."3.91Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study. ( Aibara, Y; Chayama, K; Goto, C; Hashimoto, H; Higashi, Y; Kajikawa, M; Kihara, Y; Kishimoto, S; Liao, JK; Maruhashi, T; Matsui, S; Nakashima, A; Noma, K; Oki, K; Takaeko, Y; Yusoff, FM, 2019)
" We report our long-term single-practice experience in 5 patients with chronic hyperaldosteronism (HA, including 3 with glucocorticoid remediable aldosteronism, GRA) treated with low-dose amiloride (a specific epithelial sodium channel [ENaC] blocker) 5-10 (mean 7) mg daily for 14-28 (mean 20) years."3.91Long-term BP control and vascular health in patients with hyperaldosteronism treated with low-dose, amiloride-based therapy. ( Hong, M; Hussain, T; Izzo, JL; Osmond, PJ, 2019)
"The Captopril challenge test (CCT) is an easy-conduct confirmatory test for diagnosing primary aldosteronism (PA)."3.91The captopril challenge test for diagnosing primary Aldosteronism in a Chinese population. ( Feng, WH; Li, HY; Li, P; Zhang, WJ; Zhang, Y; Zhu, DL; Zhu, KY, 2019)
" We report our long-term single-practice experience in an unusual group of five patients with chronic hyperaldosteronism (HA, including three with glucocorticoid-remediable aldosteronism, GRA) treated with low-dose amiloride (a specific epithelial sodium channel [ENaC] blocker) 5-10 (mean 7) mg daily for 14-28 (mean 20) years."3.91Maintenance of long-term blood pressure control and vascular health by low-dose amiloride-based therapy in hyperaldosteronism. ( Hong, M; Hussain, T; Izzo, JL; Osmond, PJ, 2019)
"High salt intake markedly enhances hypertension induced by angiotensin II (Ang II)."3.88Central and peripheral slow-pressor mechanisms contributing to Angiotensin II-salt hypertension in rats. ( Ahmad, M; Blaustein, MP; Hamlyn, JM; Keshtkar-Jahromi, M; Leenen, FHH; Lu, J; Wang, HW, 2018)
"In the PATHWAY-2 study of resistant hypertension, spironolactone reduced blood pressure substantially more than conventional antihypertensive drugs."3.88Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies. ( Brown, MJ; Caulfield, MJ; Cruickshank, JK; Ford, I; MacDonald, TM; Mackenzie, IS; McInnes, GT; Morant, SV; Padmanabhan, S; Salsbury, J; Sever, P; Webb, DJ; Williams, B, 2018)
"Elevated circulating uric acid has been postulated to play an important pathophysiological role in estrogen-progestin combined oral contraceptive (COC)-induced hypertension and endothelial dysfunction."3.88Inhibition of adenosine deaminase and xanthine oxidase by valproic acid abates hepatic triglyceride accumulation independent of corticosteroids in female rats treated with estrogen-progestin. ( Areola, ED; Badmus, OO; Kim, I; Michael, OS; Olatunji, LA; Omolekulo, TE, 2018)
" There are very little data about the effects of increased angiotensin II (Ang II) concentrations during pregnancy on in utero development of the fetus."3.85Prenatal exposure to angiotensin II increases blood pressure and decreases salt sensitivity in rats. ( Krskova, L; Okuliarova, M; Olexova, L; Panakova, Z; Senko, T; Svitok, P; Zeman, M, 2017)
"These results demonstrates that hypertension and insulin resistance induced by COC is associated with increased cardiac RAS and PAI-1 gene expression, which is likely to be through corticosterone-dependent but not aldosterone-dependent mechanism."3.85Activation of cardiac renin-angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder. ( Kim, IK; Olatunji, LA; Seok, YM; Usman, TO, 2017)
"Stroke-prone spontaneously hypertensive (SHRSP) rats were administered losartan, amlodipine or saline for 6 or 16weeks at the onset of prehypertension."3.85Early treatment with losartan effectively ameliorates hypertension and improves vascular remodeling and function in a prehypertensive rat model. ( He, DH; Lin, JX; Xie, Q; Xu, CS; Zhang, LM, 2017)
"Activation of angiotensinergic pathways by central aldosterone (Aldo)-mineralocorticoid receptor (MR) pathway plays a critical role in angiotensin II (Ang II)-induced hypertension."3.83Mineralocorticoid and angiotensin II type 1 receptors in the subfornical organ mediate angiotensin II - induced hypothalamic reactive oxygen species and hypertension. ( Ahmad, M; Chen, A; Huang, BS; Leenen, FH; Wang, HW; White, RA, 2016)
"Cross-sectional data of the single-center "Eplerenone in Primary Hyperparathyroidism" trial were used."3.83Parathyroid hormone, aldosterone-to-renin ratio and fibroblast growth factor-23 as determinants of nocturnal blood pressure in primary hyperparathyroidism: the eplerenone in primary hyperparathyroidism trial. ( Belyavskiy, E; Brandenburg, VM; Brussee, H; Catena, C; Fahrleitner-Pammer, A; Gaksch, M; Grübler, MR; März, W; Meinitzer, A; Perl, S; Pieske, B; Pilz, S; Scharnagl, H; Sechi, LA; Tomaschitz, A; Van Ballegooijen, AJ; Verheyen, N; Wetzel, J, 2016)
"Among patients with essential hypertension, circulating endogenous ouabain and Aldo are typically coelevated and their BP is salt-sensitive."3.83Endogenous ouabain and aldosterone are coelevated in the circulation of patients with essential hypertension. ( Brioni, E; Casamassima, N; Hamlyn, JM; Lanzani, C; Manunta, P; Messaggio, E; Simonini, M; Tentori, S; Zagato, L, 2016)
" Anthropometric parameters and aldosterone, plasma renin activity, cortisol, cortisone, Homeostasis Model Assessment Insulin Resistance (HOMA-IR), high-sensitivity C-reactive protein, adiponectin, IL-6, plasminogen activator inhibitor type 1 levels and matrix metalloproteinase-9 and matrix metalloproteinase-2 (MMP-9 and MMP-2) activities were measured."3.83Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension. ( Aglony, M; Allende, F; Bancalari, R; Baudrand, R; Campino, C; Carvajal, CA; Fardella, CE; Fuentes, CA; García, H; García, L; Kalergis, AM; Lagos, CF; Loureiro, C; Martinez-Aguayo, A; Sanhueza, S; Solari, S; Tapia-Castillo, A; Valdivia, C; Vecchiola, A, 2016)
"Thirty-three consecutive patients with essential hypertension and hypovitaminosis D underwent therapy with cholecalciferol 50 000 IU/week orally for 8 weeks."3.83Cholecalciferol treatment downregulates renin-angiotensin system and improves endothelial function in essential hypertensive patients with hypovitaminosid D. ( Bacca, A; Bernini, G; Bruno, RM; Carrara, D; Duranti, E; Ghiadoni, L; Taddei, S, 2016)
" In this study, we sought to determine if renal denervation (RDN) inhibits aldosterone expression and associated cardiovascular pathophysiological changes in angiotensin II (Ang II)-induced hypertension."3.83Renal denervation attenuates aldosterone expression and associated cardiovascular pathophysiology in angiotensin II-induced hypertension. ( Chen, DR; Chen, J; Gao, PJ; Hong, MN; Li, XD; Ma, Y; Ruan, CC; Wu, YJ; Xu, JZ; Zhu, DL, 2016)
"The objective of this article is to measure serum dehydroepiandrosterone sulfate (DHEA-S) concentration in both genders with primary aldosteronism (PA)."3.81Serum dehydroepiandrosterone sulfate concentration is lower in women with primary aldosteronism. ( Chen, AH; Huang, TS; Li, HY; Lin, YH; Wu, VC, 2015)
"Angiotensin II type 1 receptor blockade has neuroprotective effects in animal stroke models, but no effects in clinical stroke trials."3.81RAAS and stress markers in acute ischemic stroke: preliminary findings. ( Back, C; Edvinsson, L; Iversen, HK; Jensen, LT; Larsen, VA; Skovgaard, K; Thiesen, KL, 2015)
"The renal mechanisms responsible for angiotensin II (ANG II)-induced hypertension remain incompletely understood."3.81Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension. ( Li, XC; Miguel-Qin, E; Shull, GE; Zhuo, JL, 2015)
" This study suggests that telmisartan (TEL) can inhibit myocardial fibrosis of hypertensive left ventricular hypertrophy (LVH) through the transforming growth factor-β1 (TGF-β1)/Smad signaling pathway."3.80Telmisartan delays myocardial fibrosis in rats with hypertensive left ventricular hypertrophy by TGF-β1/Smad signal pathway. ( Guan, G; Ma, A; Shao, L; Tian, G; Wang, J; Wang, Y; Zhang, Y, 2014)
" On day 11, hypertension was induced by continuous angiotensin II infusion."3.80M-atrial natriuretic peptide and nitroglycerin in a canine model of experimental acute hypertensive heart failure: differential actions of 2 cGMP activating therapeutics. ( Burnett, JC; Cataliotti, A; Chen, HH; Ichiki, T; McKie, PM; Sangaralingham, SJ, 2014)
"Eplerenone is a highly selective aldosterone blocker, which has the potential to lower blood pressure (BP) in patients with hypertension."3.80The velocity of home blood pressure reduction in response to low-dose eplerenone combined with other antihypertensive drugs determined by exponential decay function analysis. ( Asayama, K; Elnagar, N; Hosaka, M; Imai, Y; Ishikura, K; Mano, N; Obara, T; Ohkubo, T; Satoh, M, 2014)
" We investigated the effects of upregulating heme-oxygenase (HO) on myocardial histo-pathological lesions, proinflammatory cytokines/chemokines, oxidative mediators and important markers of heart failure such as osteopontin and osteoprotergerin in N(ω)-nitro-l-arginine methyl ester (L-NAME)-induced hypertension."3.80Heme oxygenase suppresses markers of heart failure and ameliorates cardiomyopathy in L-NAME-induced hypertension. ( Chibbar, R; Lane, N; Ndisang, JF, 2014)
"In C57BL/6-mice, hypertension was induced by infusion of 600 ng/kg • min angiotensin II."3.80Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors. ( Amann, K; Brand, S; Mandel, P; Schupp, N; Zimnol, A, 2014)
"Aim of the study is to evaluate the impact of spironolactone (SPL) on indexes of metabolic syndrome (MS) and further investigate the mechanisms underlying its protective effects."3.79Spironolactone prevents dietary-induced metabolic syndrome by inhibiting PI3-K/Akt and p38MAPK signaling pathways. ( Liang, LY; Lin, YE; Liu, MJ; Long, HD; Zeng, ZH, 2013)
"This study was performed to determine the characteristics and mechanism of hypertension in SHR/NDmcr-cp(+/+) rats (SHRcp), a new model of metabolic syndrome, with a focus on the autonomic nervous system, aldosterone, and angiotensin II."3.79Novel mechanism for disrupted circadian blood pressure rhythm in a rat model of metabolic syndrome--the critical role of angiotensin II. ( Kataoka, K; Katayama, T; Kim-Mitsuyama, S; Koibuchi, N; Maeda, M; Matsui, K; Mingjie, M; Nakagawa, T; Ogawa, H; Sueta, D; Toyama, K; Uekawa, K; Waki, H; Yasuda, O, 2013)
"Urinary 18-hydroxycortisol has been investigated as a marker of aldosterone-producing adenoma (APA)."3.79Quantification of urinary 18-hydroxycortisol using LC-MS/MS. ( Chiba, H; Fuda, H; Fujikawa, M; Hui, SP; Ikegawa, S; Jin, S; Kurosawa, T; Sakurai, T; Takahashi, Y; Takeda, S; Wada, N; Yanagisawa, K, 2013)
"Circulating angiotensin II (Ang II) activates a central aldosterone-mineralocorticoid receptor neuromodulatory pathway, which mediates most of the Ang II-induced hypertension."3.79Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension. ( Ahmad, M; Huang, BS; Leenen, FH; White, RA, 2013)
"Flos Chrysanthemi is used in a variety of diseases in traditional Chinese medicine including hypertension, and the total flavonoids (rich in luteolin (LUT) and buddleoside (BUD)) of Flos Chrysanthemi is known to modulate vascular functions and reduce the blood pressure."3.79Combined antihypertensive effect of luteolin and buddleoside enriched extracts in spontaneously hypertensive rats. ( Chen, SH; Gao, JL; Lei, J; Li, B; Lv, GY; Yu, JJ; Zhan, RJ; Zhang, YP; Zhang, ZR, 2013)
"Leptin and aldosterone have been associated with the pathophysiological mechanisms of hypertension."3.79High-circulating leptin levels are associated with increased blood pressure in uncontrolled resistant hypertension. ( Barbaro, NR; de Faria, AP; de Haro Moraes, C; Demacq, C; Ferreira-Melo, SE; Figueiredo, VN; Júnior, HM; Martins, LC; Quinaglia, T; Sabbatini, AR, 2013)
" We report a case of 55-year-old man with primary aldosteronism (PA) whose hyperaldosteronism was suppressed with the PPAR γ agonist pioglitazone."3.79Suppression of primary aldosteronism and resistant hypertension by the peroxisome proliferator-activated receptor gamma agonist pioglitazone. ( Harada, E; Kashiwagi, Y; Mizuno, Y; Morita, S; Shono, M; Yano, M; Yasue, H; Yoshimura, M, 2013)
"In 205 patients with untreated essential hypertension, we measured components of the renin-angiotensin-aldosterone system, plasma levels of fibrinogen, D-dimer, prothrombin fragment 1 + 2 (F1 + 2), and plasminogen activator inhibitor-1 (PAI-1), and assessed cardiac characteristics with standard echocardiography."3.79Association of aldosterone with left ventricular mass in hypertension: interaction with plasma fibrinogen levels. ( Catena, C; Colussi, G; Sechi, LA; Valeri, M, 2013)
" In the present study, we investigated the contribution of aldosterone to the renal p21 expression and senescence during the development of angiotensin II (AngII)-induced hypertension."3.78Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice. ( Deguchi, K; Hitomi, H; Kitada, K; Kobori, H; Lei, B; Masaki, T; Minamino, T; Mori, H; Nakano, D; Nishiyama, A, 2012)
"5-T magnetic resonance imaging-arterial spin labeling in 34 subjects with arterial hypertension before aliskiren (pre-aliskiren), after 4 weeks of aliskiren treatment (300 mg), and 4-5 days (∼2."3.78Reversibility of the effects of aliskiren in the renal versus systemic circulation. ( Janka, R; Ott, C; Raff, U; Ritt, M; Schmieder, RE; Schneider, MP; Uder, M; Veelken, R; Ziegler, T, 2012)
" Folic acid intake has beneficial effects upon the cardiovascular system decreasing hyperhomocysteinemia, however, more studies imply that it is related with other mechanisms."3.78The effects of ethanol upon hydric balance and arterial pressure in rats: folic acid as a possible hypotensor. ( Barrero, MJ; Carreras, O; Díaz Castro, J; Murillo, ML; Nogales, F; Ojeda, ML, 2012)
"11β-hydroxysteroid dehydrogenase type 2 enzyme (11β-HSD2) inactivates cortisol (F) to cortisone (E); its impairment is associated with hypertension."3.7811β-hydroxysteroid dehydrogenase type 2 polymorphisms and activity in a Chilean essential hypertensive and normotensive cohort. ( Baudrand, R; Campino, C; Carvajal, CA; Faccini, G; Fardella, CE; Guidi, G; Kalergis, AM; Lagos, CF; Morales, M; Olivieri, O; Owen, GI; Padilla, O; Pasini, F; Quinteros, H; Thichauer, J; Valdivia, C, 2012)
"The aim of this paper is to report a case of unilateral PA with spontaneous remission and reduction of cardiac hypertrophy after long-term spironolactone (SP) therapy."3.78Unilateral primary aldosteronism with spontaneous remission after long-term spironolactone therapy. ( Demura, M; Karashima, S; Kometani, M; Takata, H; Takeda, Y; Yamagishi, M; Yoneda, T, 2012)
"Idiopathic primary hyperaldosteronism (IHA) and low-renin essential hypertension (LREH) are common forms of hypertension, characterized by an elevated aldosterone-renin ratio and hypersensitivity to angiotensin II."3.78TASK-3 channel deletion in mice recapitulates low-renin essential hypertension. ( Barrett, PQ; Bayliss, DA; Carey, RM; Guagliardo, NA; Hu, C; Schertz, EM; Tyson, DA; Yao, J, 2012)
"The finding of adipocyte-derived hormone leptin as an overstimulator of sympathetic activity brought a new perspective to the pathophysiological mechanisms of obesity-hypertension."3.78Leptin and aldosterone in sympathetic activity in resistant hypertension with or without type 2 diabetes. ( Boer-Martins, L; Demacq, C; Faria, AP; Figueiredo, VN; Martins, LC; Moraes, Cde H; Moreno, H, 2012)
" Determination of metanephrines by high-pressure liquid chromatography has been well established for the diagnosis of pheochromocytomas, demonstrating high sensitivity and specificity."3.78Plasma and urinary metanephrines determined by an enzyme immunoassay, but not serum chromogranin A for the diagnosis of pheochromocytoma in patients with adrenal mass. ( Deutschbein, T; Hinrichs, J; Mann, K; Petersenn, S; Schmidt, H; Unger, N; Walz, MK, 2012)
"To study on the difference of plasma renin activity (PRA), angiotensin II (Ang II), and aldosterone levels in patients with essential hypertension (EH) or primary aldosteronism (PA) or pheochromocytoma (PHEO), and to analyze the sensitivity and specificity on the diagnosis of PA among patients with hypertension with aldosterone/PRA ratio (ARR)."3.78[Differences of blood plasma renin activity, angiotensin II and aldosterone levels in essential or secondary hypertension]. ( Chen, S; Fu, CL; Li, M; Lu, L; Song, AL; Sun, ML; Tong, AL; Wang, YH; Zeng, ZP, 2012)
"Many studies have implicated both angiotensin II (ANG II) and aldosterone (Aldo) in the pathogenesis of hypertension, the progression of renal injury, and cardiac remodeling after myocardial infarction."3.77Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension. ( Beltz, TG; Gomez-Sanchez, CE; Guo, F; Hay, M; Johnson, AK; Xue, B; Yu, Y, 2011)
"Hypertension was induced by continuous angiotensin II (Ang II) infusion via osmotic mini-pumps over 4 weeks."3.77Effect of the plasminogen-plasmin system on hypertensive renal and cardiac damage. ( Cordasic, N; Daniel, C; Hartner, A; Heusinger-Ribeiro, J; Hilgers, KF; Klanke, B; Knier, B; Veelken, R, 2011)
"Although the anorexic effects of leptin are lost in obesity, leptin-mediated sympatho-activation is preserved."3.77Impact of leptin-mediated sympatho-activation on cardiovascular function in obese mice. ( Belin de Chantemèle, EJ; Mintz, JD; Rainey, WE; Stepp, DW, 2011)
" Since angiotensin II increases pendrin-mediated Cl(-) absorption in vitro, we asked whether angiotensin II increases pendrin expression in vivo and whether angiotensin-induced hypertension is pendrin dependent."3.77Angiotensin II acts through the angiotensin 1a receptor to upregulate pendrin. ( Agazatian, D; Bailey, JL; Coffman, TM; Farley, DB; Hong, S; Inagami, T; Kim, YH; Le, T; Matthews, SW; Pech, V; Verlander, JW; Wall, SM; Weiner, ID; Whitehill, FM, 2011)
"Hypertension was induced in cyp1a1ren-2 transgenic rats by feeding indole-3-carbinol (n = 10) and in Fischer 344 rats by subcutaneously infusing ANG II (n = 7)."3.77Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome. ( Clemetson, KJ; Gebhard, S; Gesell-Salazar, M; Greinacher, A; Hammer, E; Kuttler, B; Peters, B; Peters, J; Rettig, R; Scharf, C; Steil, L; Völker, U, 2011)
" In the present study, the effect of a subdose of fasudil, a selective ROCK inhibitor, on systemic hypertension and myocardium fibrosis induced by aldosterone was investigated in uninephrectomized Sprague-Dawley rats (SD)."3.77Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats. ( Guo, P; Masaki, T; Mori, H; Nishiyama, A; Wu, C, 2011)
" It has been reported that eplerenone has a potential antihypertensive effect, with a profile slightly different from that of spironolactone, and has fewer adverse reactions, suggesting that it may become a first-line treatment for hypertension."3.76Clinical effects of eplerenone, a selective aldosterone blocker, in Japanese patients with essential hypertension. ( Fukuda, S; Sato, A, 2010)
"Cilostazol (CILO), a selective inhibitor of phosphodiesterase 3 with potent antithrombotic property, has been shown to have a vasculoprotective effect in atherosclerosis animal models due to its potential anti-inflammatory and antioxidant actions."3.76Vasculoprotective effect of cilostazol in aldosterone-induced hypertensive rats. ( Hirata, Y; Hirono, Y; Sakurada, M; Sekizawa, N; Suzuki, N; Yoshimoto, T, 2010)
"We evaluated the circulating levels of resistin, leptin, and adiponectin, echocardiographic left ventricle (LV) parameters, and the prevalence of metabolic syndrome (SM) in subjects with PA."3.76Adipokines and cardiometabolic profile in primary hyperaldosteronism. ( Cianci, R; Cotesta, D; De Toma, G; Iacobellis, G; Letizia, C; Pergolini, M; Petramala, L; Sciomer, S; Zinnamosca, L, 2010)
"We, therefore compared, head-to-head, the aldosterone-renin ratio based on PRA with that based on DRA, at baseline and after captopril administration, for identifying aldosterone-producing adenoma (APA) in 251 patients of the Primary Aldosteronism Prevalence in hYpertension Study (PAPY)."3.76The aldosterone-renin ratio based on the plasma renin activity and the direct renin assay for diagnosing aldosterone-producing adenoma. ( Barisa, M; Belfiore, A; Desideri, G; Ferri, C; Letizia, C; Maccario, M; Mantero, F; Morganti, A; Palumbo, G; Patalano, A; Pessina, AC; Roman, E; Rossi, GP; Seccia, TM, 2010)
" The current study was designed to advance our understanding of the therapeutic potential of M-ANP in a canine model of acute angiotensin II-induced hypertension with elevated cardiac filling pressures and aldosterone activation."3.76A novel atrial natriuretic peptide based therapeutic in experimental angiotensin II mediated acute hypertension. ( Boerrigter, G; Burnett, JC; Cataliotti, A; Chen, HH; Ichiki, T; Martin, FL; McKie, PM; Sangaralingham, SJ, 2010)
"BC can inhibit left ventricular hypertrophy, plasma level of angiotensin II and aldosterone to some extent in SHR."3.76[Effects of Bai-Chuan capsule on left ventricular hypertrophy and correlative indexes]. ( Duan, HJ; He, LC; Zhan, YZ; Zhang, Y, 2010)
"The present study was performed to characterize the autoregulatory efficiency of renal blood flow and glomerular filtration rate and the pressure-natriuresis relationship in transgenic rats with inducible angiotensin II (ANG II)-dependent hypertension (Cyp1a1-Ren-2 rats)."3.75Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats. ( Bürgelová, M; Cervenka, L; Erbanová, M; Husková, Z; Kramer, HJ; Mullins, JJ; Rakusan, D; Thumová, M; Vanecková, I; Vanourková, Z, 2009)
"Genetic variation in the human angiotensinogen gene (AGT) influences plasma AGT concentration and susceptibility to essential hypertension by a mechanism that remains to be clarified."3.74Response to genetic manipulations of liver angiotensinogen in the physiological range. ( Cheng, T; Gociman, B; Hillas, E; Hunter, G; Hunter, J; Lalouel, JM; Lott, P; Monson, S; Rohrwasser, A; Ying, J, 2008)
"Cortisol has been implicated in hypertension and lately reported to be regulated at the pre-receptor level by the 11betaHSD1 enzyme, which converts cortisone (E) to cortisol (F)."3.74[Possible pathogenetic role of 11 beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) gene polymorphisms in arterial hypertension]. ( Artigas, RA; Carvajal, CA; Fardella, CE; Morales, MA; Mosso, LM; Ortiz, E; Owen, GI, 2008)
" To elucidate the potential role of local renin-angiotensin system in aldosterone-induced cardiovascular injury, we investigated the effects of selective mineralocorticoid receptor (MR) antagonist eplerenone (EPL), angiotensin (Ang) II type 1 receptor antagonist candesartan (ARB), and superoxide dismutase mimetic tempol (TEM) on the development of hypertension, vascular injury, oxidative stress, and inflammatory-related gene expression in aldosterone-treated hypertensive rats."3.74Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: the possible role of local renin-angiotensin system. ( Hirata, Y; Hirono, Y; Kobayashi, N; Sakurada, M; Shichiri, M; Sugiyama, T; Suzuki, N; Takai, S; Yoshimoto, T, 2007)
" To elucidate its significance for myocardial fibrosis in the hypertensive heart, we used a mouse model with infusion of angiotensin II and examined results by histology, immunohistochemistry, in situ hybridization, and quantitative real-time reverse transcriptase polymerase chain reaction (RT-PCR)."3.74Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation. ( Hiroe, M; Imanaka-Yoshida, K; Inada, H; Nishioka, T; Onishi, K; Suzuki, M; Takakura, N; Yoshida, T, 2007)
" We investigated its role in angiotensin II-induced hypertension in the Tsukuba hypertensive mouse (THM)."3.74Absence of peroxisome proliferator-activated receptor-alpha abolishes hypertension and attenuates atherosclerosis in the Tsukuba hypertensive mouse. ( Bak, S; Coleman, T; Osher, E; Semenkovich, CF; Stern, N; Tordjman, KM; Vechoropoulos, M; Yudovich, R, 2007)
"Renin-angiotensin system gene polymorphisms are associated with essential hypertension; angiotensinogen gene variants are considered potential genetic risk factors."3.74Significance of angiotensinogen gene haplotypes and genotypes combinations in hypertension. ( Goyal, AK; Gupta, M; Javed, S; Kumar, R; Nejatizadeh, A; Pasha, MQ; Stobdan, T, 2008)
"We correlated the BP response to spironolactone 50 mg/day to baseline ARR in 69 hypertensive patients (mean [+/-SD] age 57 +/- 2 years, 65% male), consisting of 39 subjects with long-standing hypertension (4."3.73Does aldosterone-to-renin ratio predict the antihypertensive effect of the aldosterone antagonist spironolactone? ( Feely, J; Hall, M; Mahgoub, M; Mahmud, A, 2005)
"To compare efficacy of use of the blocker of aldosteron receptors spironolactone and diuretic indapamide in low-renin arterial hypertension (AH), their action on blood pressure, serum concentrations of sodium, potassium, creatinine, plasmic renin activity (PRA), plasmic aldosteron concentration (PAC)."3.73[Use of spironolactone and indapamide in the treatment of low-renin arterial hypertension]. ( Bagdonas, G; Kazanavichus, G; Naudzhunas, A; Yankauskene, L, 2006)
" Since chronic inhibition of nitric oxide (NO) synthase with N(omega)-nitro-L-arginine methyl ester (L-NAME) induces systemic hypertension associated with cardiovascular inflammation and remodeling, we examined the potential role of aldosterone in this process using eplerenone, a selective aldosterone receptor antagonist."3.73The antagonism of aldosterone receptor prevents the development of hypertensive heart failure induced by chronic inhibition of nitric oxide synthesis in rats. ( Asano, Y; Fujita, M; Hirata, A; Hori, M; Kitakaze, M; Minamino, T; Okada, K; Sanada, S; Shintani, Y; Takashima, S; Tomoike, H; Tsukamoto, O; Yamasaki, S; Yulin, L, 2006)
"To investigate the association of aldosterone synthase (CYP11B2) -344T/C polymorphism with plasma renin activity (PRA), and concentrations of angiotensin II (Ang II) and aldosterone (Aldo) in patients with essential hypertension (EH)."3.73[Association of aldosterone synthase gene -344T/C polymorphism with plasma aldosterone and angiotensin II concentration in hypertensive patients]. ( Chu, SL; Gao, PJ; Hu, BC; Wang, GL; Wang, JG; Wang, ZH; Zhu, DL, 2006)
"A unique model of hypertension developed in our laboratory shows that neonatal degeneration of capsaicin-sensitive sensory nerves renders a rat responsive to salt load with a significant rise in blood pressure."3.72Increased salt sensitivity induced by impairment of sensory nerves: is nephropathy the cause? ( Wang, DH; Zhao, Y, 2003)
"Losartan attenuates BSO-induced hypertension, which appears to be mediated, in part, by angiotensin II and the prostanoid endothelium-derived factors."3.72Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats. ( Abukhalaf, IK; Bayorh, MA; Eatman, D; Ganafa, AA; Silvestrov, N; Socci, RR, 2003)
"The effects of low-dose oral spironolactone (SPIRO) in a rat model of hypertensive heart failure (spontaneously hypertensive heart failure rat) were compared with its effects when combined with captopril (CAP)."3.72Combined effects of low-dose oral spironolactone and captopril therapy in a rat model of spontaneous hypertension and heart failure. ( Bauer, JA; Ghosh, S; Holycross, BJ; Kambara, A; Kwiatkowski, P; McCune, SA; Schanbacher, B; Wung, P, 2003)
"We investigated the pathophysiological role of the cardiac adrenomedullin (AM) system, including the ligand, receptor and amidating activity in the hypertrophied heart in severe hypertension."3.72Upregulation of ligand, receptor system, and amidating activity of adrenomedullin in left ventricular hypertrophy of severely hypertensive rats: effects of angiotensin-converting enzyme inhibitors and diuretic. ( Akimoto, K; Minamino, N; Mori, Y; Nishikimi, T; Tadokoro, K; Wang, X, 2003)
" This study investigated whether cyclooxygenase-2 expression is regulated in the kidney, in an angiotensin II- and aldosterone-induced hypertension model."3.72Analysis of angiotensin II mediated COX-2 downregulation in angiotensin II- or aldosterone-infused hypertensive rat. ( Lee, YJ; Lim, WC; Park, JB, 2003)
"When performed with careful regard to confounding factors, measurement of the aldosterone : renin ratio in all hypertensive individuals, followed by fludrocortisone suppression testing to confirm or exclude primary aldosteronism and adrenal venous sampling to determine the subtype, can result in the detection of significant numbers of patients with specifically treatable or potentially curable hypertension."3.72High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients. ( Archibald, C; Cowley, DC; Gordon, RD; Gunasekera, TG; Smithers, BM; Stowasser, M; Ward, G, 2003)
"In Lyon hypertensive (LH) rats, a model of low-renin genetic hypertension, we investigated adrenal sensitivity to angiotensin II in terms of angiotensin II receptor (AT1 and AT2 receptors) regulation, morphological changes, and aldosterone and corticosterone secretion."3.72Hypersensitivity of the adrenal cortex to trophic and secretory effects of angiotensin II in Lyon genetically-hypertensive rats. ( Aguilar, F; Claustrat, B; Li, JY; Lo, M; Saez, JM; Sassard, J, 2004)
"Functional changes in the kidneys of healthy men with (FH+) (n = 15) and without (FH-) (n = 15) family history of primary arterial hypertension were examined during administration of low-dose exogenous angiotensin II (A2) (1 ng/kg per min) before and after acute (1 mg intravenous enalaprilat) and chronic (7 days oral enalapril, 30 mg/day) angiotensin-converting enzyme (ACE) inhibition."3.72Increased renovascular response to angiotensin II in persons genetically predisposed to arterial hypertension disappears after chronic angiotensin-converting enzyme inhibition. ( Bock, A; Dieterle, T; Drewe, J; Gyr, K; Haberthür, C; Huber, PR; Martina, B; Schächinger, H, 2004)
"There are not studies about the utility of modified liberation doxazosin (MLD) in the combined treatment of the true resistant hypertension (TRH)."3.72[Effect of modified liberation doxazosin on blood pressure, insulin resistance, and catecholamine secretion in patients with true resistant hypertension]. ( Aliaga Martínez, L; Fernández-Torres, C; Jiménez-Alonso, J; Mediavilla García, JD; Sabio, JM, 2004)
"The dual ACE+NEP inhibitor MDL prevented and regressed severe hypertension and cardiovascular damage, even in this model of severe angiotensin II-dependent hypertension with pronounced cardiovascular damage."3.71Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor. ( Agabiti-Rosei, E; Bova, S; Cavallin, M; Mazzocchi, G; Nussdorfer, GG; Pessina, AC; Rizzoni, D; Rossi, GP, 2002)
"Aldosterone-induced hypertension is associated with renal damage that may be mediated by endothelin-1 (ET-1)."3.71Contribution of endothelin-1 to renal activator protein-1 activation and macrophage infiltration in aldosterone-induced hypertension. ( Chen, X; He, G; Schiffrin, EL; Tostes, RC; Touyz, RM, 2002)
"In 43 untreated patients with hypertension with electrocardiographic left ventricular hypertrophy, we measured relative wall thickness and left ventricular mass index by echocardiography and by magnetic resonance imaging (n = 32), intima-media cross-sectional area, and distensibility of the common carotid arteries by ultrasound, media/lumen ratio of isolated subcutaneous resistance arteries by myography, and median 24-hour systolic BP (n = 40), serum insulin, and plasma levels of epinephrine, norepinephrine, renin, angiotensin II, aldosterone, and endothelin."3.71Is cardiovascular remodeling in patients with essential hypertension related to more than high blood pressure? A LIFE substudy. Losartan Intervention For Endpoint-Reduction in Hypertension. ( Devereux, RB; Dige-Petersen, H; Frandsen, E; Hermann, KL; Ibsen, H; Olsen, MH; Rokkedal, J; Wachtell, K, 2002)
"The aim of the study was to compare hypotensive reaction after treatment with enalapril and enalapril with isosorbide mononitrate in patients with mild and moderate hypertension."3.71[Effect of isosorbide mononitrate on hypotensive action of enalapril in patients with mild and moderate hypertension]. ( Przewłocka-Kosmala, M, 2002)
"The renin-angiotensin-aldosterone system plays a major role in the pathogenesis of hypertension by enhancing the production or the activity of angiotensin II (ANG II)."3.71Hormone replacement therapy increases plasma level of angiotensin II in postmenopausal hypertensive women. ( Ichikawa, S; Kanda, T; Kobayashi, I; Sumino, H; Umeda, M, 2001)
"Increased endothelin-1 may be associated with elevation of blood pressure (BP) and promotion of vascular hypertrophy, especially in salt-sensitive hypertension."3.71ET(A) receptor antagonist prevents blood pressure elevation and vascular remodeling in aldosterone-infused rats. ( Park, JB; Schiffrin, EL, 2001)
"An increased sensitivity to angiotensin II (Ang II) has been observed in patients with established hypertension."3.71Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension. ( Delles, C; Jacobi, J; Klingbeil, AU; Schlaich, MP; Schmidt, BM; Schmieder, RE; Schneider, MP, 2002)
"(1) Salt sensitive hypertension, which occurs as a result of treatment with nitric oxide synthase inhibitors, is associated with a loss of the usual down-regulatory effect of dietary sodium on angiotensin II (Ang II) synthesis."3.71Dysregulation of angiotensin II synthesis is associated with salt sensitivity in the spontaneous hypertensive rat. ( Duggan, KA; Hodge, G; Ye, VZ, 2002)
"Spironolactone is a safe, effective therapy for patients with refractory hypertension."3.71The role of spironolactone in the treatment of patients with refractory hypertension. ( Carré, E; Lincoff, AM; Mertes, M; Ouzan, J; Pérault, C, 2002)
"In a previous study, we showed that dietary gamma-linolenic acid (GLA), an omega-6 polyunsaturated fatty acid found in borage oil (BOR), attenuates the development of hypertension in young spontaneously hypertensive rats (SHR)."3.70Effects of dietary gamma-linolenic acid on blood pressure and adrenal angiotensin receptors in hypertensive rats. ( Ball, DL; Engler, MB; Engler, MM; Goodfriend, TL; Schambelan, M, 1998)
"The angiotensinogen gene has recently been linked to essential hypertension."3.70T235 variant of the angiotensinogen gene and blood pressure in the Chilean population. ( Claverie, X; Fardella, CE; Montero, J; Vignolo, P; Villarroel, L, 1998)
"In 30 normotensive individuals and 30 subjects with mild essential hypertension (white men, mean age 26+/-3 years), the responsiveness to angiotensin II was assessed by measuring changes in mean arterial pressure, renal blood flow, glomerular filtration rate and aldosterone secretion in response to i."3.70Hyper-responsiveness to angiotensin II is related to cardiac structural adaptation in hypertensive subjects. ( Hilgers, K; Klingbeil, AU; Langenfeld, MR; Schäufele, T; Schmieder, RE; Schobel, H, 1999)
" The antistroke effects of captopril treatment occurred without an antihypertensive effect, weren't altered by enhancing hypertension during treatment (with dexamethasone), and couldn't be duplicated by antihypertensive treatment with hydralazine."3.70Effect of poststroke captopril treatment on mortality associated with hemorrhagic stroke in stroke-prone rats. ( King, SR; Smeda, J; Vasdev, S, 1999)
" Five of these patients with aldosterone producing adenoma were operated on and four patients with idiopathic hyperaldosteronism were treated with spironolactone."3.70Insulin action in primary hyperaldosteronism before and after surgical or pharmacological treatment. ( Haas, T; Hilgertová, J; Prázný, M; Sindelka, G; Skrha, J; Widimský, J, 2000)
"Clinical evaluation of hypotensive effectiveness and the cardiovascular and side effects of enalapril monotherapy of significant essential hypertension (SEH) in adolescents was performed."3.69[Evaluation of the efficacy and safety of monotherapy for significant essential hypertension in adolescents with use of enalapril]. ( Cichocka, E; Januszewicz, P; Kawalec, W; Wyszyńska, T, 1995)
"Flosequinan (BTS 49465, 7-fluoro-1-methyl-3-methyl-sulphinyl-4-quinolone), a recently direct-acting vasodilator that should cause relatively less reflex tachycardia, was given in a single oral dose of 200 mg to 10 untreated patients with moderate to severe hypertension."3.69Acute effects of flosequinan (BTS 49465) in untreated moderate to severe hypertension. ( Janssen, MC; Reyenga, J; Smits, P; Thien, T, 1995)
"The transgenic TGR(mRen-2)27 rat, in which the Ren-2 mouse renin gene is transfected into the genome of the Sprague-Dawley rat, develops severe hypertension at a young age that responds to inhibitors of angiotensin-converting enzyme and to antagonists of the type 1 angiotensin II (Ang II) receptor."3.69Angiotensin and bradykinin peptides in the TGR(mRen-2)27 rat. ( Campbell, DJ; Ganten, D; Kladis, A; Rees, B; Rong, P; Skinner, SL, 1995)
"The nonmodulating trait thought to explain development of hypertension in 25 to 35% of patients, is characterized by abnormal angiotensin II (AII)-mediated control of aldosterone release and renal blood flow (RBF)."3.69Nonmodulating trait may precede the development of hypertension. ( Gordon, MB; Gordon, MS; Hollenberg, NK; Williams, GH, 1994)
"In twelve hypertensive patients with end-stage renal disease (ESRD) due to chronic glomerulonephritis (CGN), the mechanisms of renin and aldosterone regulation were studied by exogenously infused angiotensin II, captopril, and upright posture."3.69The impaired control of plasma renin activity in hypertensive patients with end-stage renal disease due to chronic glomerulonephritis. ( Ishii, M; Nagasawa, T; Shionoiri, H; Umemura, S; Yasuda, G, 1994)
"Ten cases of adrenal adenomas, one case with unilateral adrenal hyperplasia, and another case with apparent bilateral are reported, in whom an alternative pathway of aldosterone via 21-deoxyaldosterone is operative."3.69A new subset of mineralocorticoid hypertension with excess of 21-deoxyaldosterone and Kelly's-M1 steroid: clinical and morphological findings. ( Abdelhamid, S; Bönhof, JA; Haack, D; Lewicka, S; Müller-Lobeck, H; Nensel, U; Pahl, S; Remberger, K; Röckel, A; Vecsei, P, 1995)
"The T235 allele of the angiotensinogen gene (AGT) has been associated with hypertension."3.69The serum angiotensinogen concentration and variants of the angiotensinogen gene in white and black children. ( Bloem, LJ; Manatunga, AK; Pratt, JH; Tewksbury, DA, 1995)
"We examined plasma renin activity (PRA), plasma aldosterone (PA), atrial natriuretic factor (ANF) and endogenous digitalis-like factor (DLF) in 15 healthy subjects and 15 patients with essential hypertension (EH) to obtain basal values and values after extracellular fluid volume (ECFV) expansion caused by infusion of isotonic saline solution over a period of 2 hours (20 mg/kg)."3.69The role of endogenous digitalis-like factor in blood pressure regulation in essential hypertension. ( Lichardus, B; Machánová, Y; Murár, J; Pjescák, M; Rosochová, I; Suchmanová-Lazúrová, I; Trejbal, D, 1994)
" To define possible cellular mechanisms involved in central mineralocorticoid action, benzamil, an amiloride analogue with selective affinity for the Na+ channel, was continuously infused intracerebroventricularly in three mineralocorticoid-dependent hypertension models in Sprague-Dawley rats, the continuous subcutaneous infusion of aldosterone, the intracerebroventricular infusion of aldosterone, and the ingestion of carbenoxolone, a synthetic licorice analogue."3.69Effect of central amiloride infusion on mineralocorticoid hypertension. ( Gomez-Sanchez, CE; Gomez-Sanchez, EP, 1994)
"To investigate the possible role of dopamine, a catecholamine with natriuretic properties, in modulating the escape from the sodium-retaining effects of mineralocorticoids, we submitted six aldosterone-producing adenoma (APA) patients and six low-renin essential hypertensive patients to acute volume expansion by head-out water immersion with or without dopaminergic blockade by metoclopramide."3.69Escape from the sodium-retaining effects of mineralocorticoids: is there a role for dopamine? ( Coruzzi, P, 1994)
"11 beta-Hydroxysteroid dehydrogenase (11 beta-HSD) activity in mesenteric arteries of 4-week- and 8-week-old Dahl rats was determined to evaluate the relationship between glucocorticoids and norepinephrine in hypertension, 11 beta-HSD activity (expressed as the percentage conversion of 3H-corticosterone (B) to 3H-11-dehydrocorticosterone (A)) significantly decreased in 8-week-old Dahl salt-sensitive (DS) rats (11."3.69Decreased activity of 11 beta-hydroxysteroid dehydrogenase in mesenteric arteries of Dahl salt-sensitive rats. ( Hatakeyama, H; Iki, K; Miyamori, I; Takeda, R; Takeda, Y; Yoneda, T, 1994)
" Study 1: A long-term (4 weeks) treatment with slow-release nifedipine (Nif), 40-60 mg/day, was performed in 9 in-patients with essential hypertension (EHT)."3.69[Mechanism of inhibition of aldosterone secretion by a Ca2+ channel blocker in patients with essential hypertension and patients with primary aldosteronism]. ( Iimura, O; Shimamoto, K; Yokoyama, T, 1995)
"Approximately half of Caucasian patients with essential hypertension and with hyperaldosteronism exhibit elevated circulating levels of endogenous ouabain."3.69Immunoreactive endogenous ouabain in primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels. ( De Toni, R; Hamlyn, JM; Manunta, P; Pavan, E; Pessina, AC; Rossi, G; Semplicini, A, 1995)
"The present study aimed to assess the influence of a highly industrialized environment on the prevalence of arterial hypertension and plasma levels of cholesterol, uric acid, aldosterone and plasma renin activity."3.69Does industrial environment influence the prevalence of arterial hypertension, plasma cholesterol and uric acid concentration and activity of the renin-aldosterone system? ( Kokot, F; Wiecek, A, 1996)
" A patient with severe hypertension was found to have mildly impaired 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD) activity on the basis of urinary steroid metabolite ratios, low plasma aldosterone, angiotensin II and renin levels and marginally low levels of plasma potassium."3.69Sodium status, corticosteroid metabolism and blood pressure in normal human subjects and in a patient with abnormal salt appetite. ( Collier, A; Connell, JM; Fraser, R; Ingram, MC; Wallace, AM, 1996)
" Urinary excretion rates of calcium, sodium, chloride, potassium, urinary calcium/creatinine index, the fractional excretion of sodium, potassium and uric acid, the creatinine clearance and serum values of creatinine, urea, uric acid, electrolytes, total proteins, parathormone (intact molecule), plasma renin activity, aldosterone, glucose, and insulin (fasting and after an oral glucose load) were performed in every patient and control subject."3.69Urinary calcium excretion in treated and untreated essential hypertension. ( Navarro-Antolin, J; Orte, L; Ortuño, J; Quereda, C; Sabater, J; Villafruela, JJ, 1996)
"Nifedipine is a commonly used agent in treating hypertension and angina because of its vasodilator properties."3.69Effects of nifedipine treatment on the renin-angiotensin-aldosterone axis. ( Cunningham, SK; Fiad, TM; Hayes, FJ; McKenna, TJ, 1997)
" Tsukuba hypertensive mice (THM) carry both human renin and angiotensinogen genes, and develop hypertension."3.69Development of polyuria in Tsukuba hypertensive mice carrying human renin and angiotensinogen genes. ( Fukamizu, A; Ikemoto, F; Mino, N; Murakami, K; Nishikibe, M; Tsuchida, M; Uehara, S, 1995)
" We measured the urinary excretion of 19-noraldosterone in the spontaneously hypertensive rat (SHR) and stroke-prone SHR (SHRSP) during the development of hypertension and compared these measurements with Wistar-Kyoto (WKY) rats."3.69Urinary excretion of 19-noraldosterone in the spontaneously hypertensive rat and stroke-prone spontaneously hypertensive rat. ( Hurukawa, K; Inaba, S; Ito, Y; Miyamori, I; Takeda, R; Takeda, Y; Yoneda, T, 1995)
"The angiotensinogen gene is one of the very few related by linkage analysis to human hypertension, but the linkage has been consistently shown only among males."3.69Age, gender, and non-modulation. A sexual dimorphism in essential hypertension. ( Bellini, C; Ferri, C; Fisher, ND; Gleason, R; Hollenberg, NK; Santucci, A; Seely, EW; Williams, GH, 1997)
" Infusion of ebelactone B, (a selective inhibitor of carboxypeptidase Y-like exopeptidase, a kininase in rat urine), to normal BN-Ki rats during induction of hypertension with DOCA and salt, resulted in the reduction of the raised blood pressure, indicating that a site of action of kinins was at the luminal membrane of the renal tubule cells."3.69Role of the renal kallikrein-kinin system in the development of hypertension. ( Katori, M; Majima, M, 1997)
"Myocardial fibrosis, associated with increased expression of angiotensin converting enzyme (ACE) and bradykinin (BK) receptor binding at sites of tissue repair, accompanies chronic elevations in circulating angiotensin II (AngII) and/or aldosterone (ALDO) that simulate chronic cardiac failure."3.69Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion. ( Ramires, FJ; Sun, Y; Weber, KT, 1997)
"Elevations in plasma aldosterone enhance stroke development within captopril-treated SHRSP through mechanisms that do not involve stimulation of mineralocorticoid receptors or the enhancement of hypertension."3.69The role of blood pressure and aldosterone in the production of hemorrhagic stroke in captopril-treated hypertensive rats. ( MacLeod, AB; Smeda, JS; Vasdev, S, 1997)
"We have investigated the possible involvement of endogenous corticosteroids in the maintenance of hypertension in aged lean and obese Zucker rats using the type II corticosteroid antagonist mifepristone."3.69Effects of the glucocorticoid II receptor antagonist mifepristone on hypertension in the obese Zucker rat. ( Clapham, JC; Turner, NC, 1997)
"A 49-year-old man with liver cirrhosis and hypertension was found to have hyperkalemia out of a degree of renal insufficiency and metabolic acidosis with low to normal anion gap, aggravated by volume contraction with diarrhea and medications (captopril, spironolactone and atenolol) interfering with potassium homeostasis."3.68Hyperkalemia due to hyporeninemic hypoaldosteronism with liver cirrhosis and hypertension. ( Ahn, YH; Chang, DK; Choi, JW; Kee, CS; Kim, HJ, 1993)
" Failure to suppress aldosterone with fludrocortisone acetate administration and oral salt loading confirmed the presence of primary aldosteronism in all six patients."3.68Evidence that primary aldosteronism may not be uncommon: 12% incidence among antihypertensive drug trial volunteers. ( Gordon, RD; Klemm, SA; Stowasser, M; Tunny, TJ; Ziesak, MD, 1993)
"The present study was designed to investigate the effect of L-arginine administration on patients with essential and secondary hypertension by measuring haemodynamic parameters, neuroendocrine hormones and indicators of nitric oxide (NO) release."3.68Role of L-arginine-nitric oxide pathway in hypertension. ( Hishikawa, K; Kato, R; Nakaki, T; Saruta, T; Suzuki, H, 1993)
"Clinical studies were performed on patients with mild-to-moderate essential hypertension to elucidate the efficacy and mode of action of manidipine."3.68Efficacy and mode of action of manidipine: a new calcium antagonist. ( Iimura, O; Shimamoto, K, 1993)
"Vascular permeability of the coronary and mesenteric circulation is increased in association with the arterial hypertension that accompanies either endogenous activation of the renin-angiotensin-aldosterone system (RAAS) or exogenous administration of angiotensin II (AII)."3.68Coronary microvascular fluid flux and permeability: influence of angiotensin II, aldosterone, and acute arterial hypertension. ( Campbell, SE; Janicki, JS; Reddy, HK; Weber, KT; Zhou, G, 1993)
"To evaluate the atrial natriuretic peptide response to angiotensin II (Ang II) infusion in non-modulating hypertension, we studied 31 men with essential hypertension."3.68Atrial natriuretic peptide in non-modulating essential hypertension. ( Balsano, F; Ferri, C; Luparini, RL; Santucci, A, 1993)
"A case of primary aldosteronism treated with spironolactone therapy has been followed up for 24 years."3.68Twenty-four year spironolactone therapy in an aged patient with aldosterone-producing adenoma. ( Hashimoto, T; Ito, Y; Koshida, H; Miyamori, I; Morimoto, S; Morise, T; Takeda, R; Yamazaki, T, 1992)
"To examine the role of mineralocorticoids in the pathophysiology of pregnancy-induced hypertension (PIH), we studied plasma aldosterone and 18-hydroxycorticosterone levels in 25 women with PIH and 25 normal pregnant women, as controls."3.68Mineralocorticoids and mineralocorticoid receptors in mononuclear leukocytes in patients with pregnancy-induced hypertension. ( Bastert, G; Bauer, H; E-Mistry, N; Stolz, W; Vecsei, P; Wacker, J, 1992)
"The effect of manidipine on cardiac hypertrophy, coronary circulation, left ventricular weight and maximal coronary flow in hypertension was measured in DOCA/salt treated systolic hypertensive rats with and without manidipine treatment."3.68Effect of manidipine on cardiac hypertrophy and coronary circulation in DOCA/salt hypertensive rats. ( Asayama, J; Itoh, H; Kuwabara, T; Nakagawa, M; Nakata, T; Sasaki, S; Takeda, K; Takesako, T; Tanabe, S; Yamahara, Y, 1992)
"The effect of treatment of hypertension with nifedipine on plasma renin activity, blood serum level of aldosterone in the course of renin test, and cortisol and growth hormone concentrations after stimulation with insulin hypoglycemia was followed during two weeks of treatment in 40 patients with essential hypertension."3.68[Effect of nifedipine treatment on the renin-aldosterone system and secretion of cortisol and growth hormone in patients with essential hypertension]. ( Kokot, F; Wnuk, R, 1991)
"To clarify the hemodynamic and endocrine mechanisms of the hypotensive effect of amosulalol, an alpha- and beta-adrenoceptor antagonist, 19 patients with essential hypertension received amosulalol (20-80 mg/day; average 48."3.68Hemodynamic and endocrine changes associated with hypotensive action of amosulalol in essential hypertension. ( Ando, K; Fujita, T; Noda, H; Ogata, E, 1992)
"Aim of this study was to assess the relationship between plasma concentration of atrial natriuretic factor (ANF) and its two-dimensional echocardiographic (left ventricular mass, left atrium diameter) and humoral (plasma renin and aldosterone) variables in essential hypertension (EH)."3.68Atrial natriuretic factor in essential hypertension: echocardiographic and humoral correlates. ( Favilla, S; Lattanzi, F; Lucarini, AR; Marini, C; Salvetti, A; Urbani, MP, 1992)
"This study was conducted to elucidate renal uric acid metabolism in patients with primary aldosteronism (PA;16 cases) as compared with normotensive subjects (NT;25 cases) and essential hypertensives (EHT;51 cases)."3.68[Study on uric acid metabolism in patients with primary aldosteronism]. ( Iimura, O; Kikuchi, K; Komura, H; Marusaki, S; Namba, M; Ohtomo, T; Satoh, N; Suzuki, S; Takada, T, 1992)
"Urinary excretion of 18-hydroxycortisol (18-OHF), 18-hydroxycorticosterone (18-OHB) and aldosterone 18-glucuronide (Aldo-18-glu) was measured in 10 patients with primary aldosteronism; 5 with aldosterone-producing adenoma (APA) and 5 with idiopathic hyperaldosteronism (IHA), 10 patients with essential hypertension (EHT) and 11 normotensive subjects."3.68Determination of urinary 18-hydroxycortisol in the diagnosis of primary aldosteronism. ( Iki, K; Itoh, Y; Miyamori, I; Takasaki, H; Takeda, R; Takeda, Y, 1992)
"Plasma concentrations of renin and aldosterone were measured before and 60 min after taking 25 mg captopril in 242 patients with arterial hypertension (124 men, 118 women, aged 51."3.68[Does the captopril test improve the diagnosis of primary hyperaldosteronism?]. ( Bönner, G; Degenhardt, S; Grimm, U; Krone, W; Stimpel, M; Wambach, G, 1992)
" In 10 patients with essential hypertension, we investigated the influence of betaxolol, a selective beta 1-adrenergic blocking agent, on renal function and on plasma levels of ANP during exercise, volume depletion and volume expansion."3.68Influence of betaxolol on renal function and atrial natriuretic peptide in essential hypertension. ( Grabensee, B; Heering, P; Hollenbeck, M; Kutkuhn, B; Plum, J, 1991)
" Even though the angiotensin converting enzyme inhibitor captopril was previously found to attenuate this interstitial and perivascular fibrosis, the relative importance of arterial and ventricular systolic pressures versus circulating angiotensin II (AII) and aldosterone (AL) in promoting hypertrophy and collagen accumulation in renovascular hypertension is uncertain."3.68Remodeling of the rat right and left ventricles in experimental hypertension. ( Brilla, CG; Janicki, JS; Pick, R; Tan, LB; Weber, KT, 1990)
"Plasma levels of atrial natriuretic factor were measured in 71 patients with essential hypertension and 13 with borderline arterial hypertension by using radioimmunoassay."3.68[Atrial natriuretic factor in patients with hypertension]. ( Bil'chenko, AV; Vasil'ev, IuM, 1991)
"130 cases of patients with essential hypertension (EH) and 70 cases of normal subjects were researched for correlation between TCM differential types and plasma levels of renin, angiotension II, aldosterone, atrial natriuretic factor (ANF) in patients with EH."3.68[Relation between traditional Chinese medicine differential types and plasma levels of renin, angiotension II, aldosterone, atrial natriuretic factor in patients with essential hypertension]. ( Li, H, 1991)
"Plasma levels of atrial natriuretic peptide (ANP) were measured in patients with normal renin essential hypertension (n = 12), low renin essential hypertension (n = 11) and primary aldosteronism due to aldosterone producing adenoma (APA, n = 8) and idiopathic hyperaldosteronism (IHA, n = 3) after overnight rest in the supine position and after 4 h upright posture and furosemide administration."3.68Dissociation of plasma atrial natriuretic peptide responses to upright posture and furosemide administration in patients with normal-, low renin essential hypertension and primary aldosteronism. ( Fütö, L; Gláz, E; Gutkowska, J; Kiss, R; Rácz, K; Sergev, O; Varga, I, 1991)
"To study the effects of a novel angiotensin I converting enzyme inhibitor (ACEI) on hypertension-induced cardiac hypertrophy, benazepril hydrochloride (CGS 14824 A, CAS 86541-74-4) at the dose of 3 and 10 mg/kg/d p."3.68Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneously hypertensive rats. ( Hasegawa, Y; Inukai, T; Katahira, J; Nakao, K; Takemori, E, 1991)
"0% by weight) of the neutral amino acid, L-tryptophan, on the development of hypertension during chronic exposure to cold."3.68Effect of chronic dietary treatment with L-tryptophan on the development of cold-induced hypertension in rats. ( Baron, A; Cade, JR; Fregly, MJ; Riesselmann, A, 1991)
"An attenuation of adrenergic activity during the inhibition of endogenous angiotensin II formation was evaluated by determining plasma norepinephrine concentration after a single oral administration of captopril compared to that after nifedipine in essential hypertension."3.68Captopril attenuates reflex adrenergic response in essential hypertension. ( Masuyama, Y; Mohara, O, 1991)
"The effects of the mineralocorticoid antagonist mespirenone on the development and maintenance of aldosterone-induced hypertension in Sprague-Dawley rats has been studied."3.68Effect of a new mineralocorticoid antagonist mespirenone on aldosterone-induced hypertension. ( Agarwal, M; Kalimi, M; Opoku, J; Qureshi, D, 1991)
"This case of Conn's syndrome demonstrates long-term (seven years) efficacy of triamterene-thiazide therapy in controlling both hypertension and hypokalemia."3.68Long-term medical management of aldosterone-producing adenoma. ( Bornemann, M, 1990)
" They investigated therefore in 15 patients with essential hypertension (EH) and in three patients with pheochromocytoma the urinary excretion of free noradrenaline (NA), adrenaline (A) and dopamine (DA), the plasma renin activity (PRA), the aldosterone concentration (PAC) and atrial natriuretic factor (ANF) in plasma, using radioimmunoanalysis, always before and 24 hours after clonidine administration (Haemiton retardR) by the oral route."3.68[The effect of clonidine on humoral factors in patients with arterial hypertension]. ( Dvoráková, J; Gregorová, I; Horký, K; Kopecká, J; Poliak, M, 1990)
"Atrial natriuretic factor (ANF) may play a role in the regulation of the changes of blood volume and vascular reactivity during pregnancy and when pregnancy is complicated by hypertension."3.68Plasma atrial natriuretic factor levels during normal pregnancy and pregnancy complicated by diabetes mellitus and hypertension. ( Atkinson, AB; McCance, DR; McKnight, JA; Roberts, G; Sheridan, B; Traub, AI, 1990)
" furosemide administration in 10 offsprings of normotensive subjects who had a normal Na(+)-K+ cotransport activity and in 26 normotensive men with a positive family history of essential hypertension."3.68Vasoactive humoral systems and sodium transport in erythrocytes of normotensive offsprings of essential hypertensive subjects. ( Bultasová, H; Janata, V; Pinsker, P, 1990)
"Eight patients with mild to moderate uncomplicated essential hypertension who had been taking nifedipine 20 mg twice daily for at least six weeks."3.68Long term reduction in sodium balance: possible additional mechanism whereby nifedipine lowers blood pressure. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Pevahouse, JB; Sagnella, GA, 1990)
" the main representatives of sodium retaining systems, and of the atrial natriuretic factor (ANF) the decisive natriuretic substance in acute expansion of the extracellular volume (ECV) by infusion of two litres of saline in six controls, seven patients with essential hypertension and liver cirrhosis without ascites (6 patients) and with ascites (6 patients)."3.68[Mutual interaction of the renin-angiotensin system and the atrial natriuretic factor in the renal response to acute volume loading]. ( Dvoráková, J; Gregorová, I; Horký, K; Srámková, J; Tesar, V, 1990)
"The effect of a single oral dose (50 mg) of captopril was studied in 12 hypertensive patients divided into 2 groups: 6 had a normal hemodynamic profile; the other 6 had NYHA class III or IV heart failure."3.68[Captopril and hypertensive cardiopathy : therapeutic effects and hormonal changes]. ( D'Aprile, N; Faglia, S; Galli, M; Kristodhullu, S; Martorelli, T; Mondillo, S; Palazzuoli, V, 1990)
"This study was undertaken to clarify the role of dopamine receptor (DA2) on the effects of atrial natriuretic polypeptide(ANP) on blood pressure, plasma and urinary cyclic GMP, and urinary sodium excretion, alpha-human ANP (alpha-hANP) was intravenously administrated to 7 normal subjects and 14 patients with essential hypertension as follows: first a dose of 0."3.68[The significance of cGMP and dopamine receptor on the natriuretic and hypotensive activities of synthetic atrial natriuretic polypeptide in essential hypertension]. ( Fukuchi, S; Haga, H; Kato, K; Kin, S; Kohno, H; Mori, K; Shigetomi, S; Tanaka, K; Tosaki, H, 1990)
"This study investigated the ability of two diuretics, amiloride and frusemide, to prevent the development of ACTH induced hypertension in conscious sheep."3.68Amiloride blocks the onset of ACTH-induced hypertension in the sheep. ( Coghlan, JP; Reid, AF; Scoggins, BA; Whitworth, JA, 1990)
"The effects of 1-year antihypertensive treatment with the diuretic fenquizone were evaluated in 16 patients with mild essential hypertension."3.68Hemodynamic and humoral effects of chronic antihypertensive treatment with fenquizone: importance of aldosterone response. ( Ambrosioni, E; Borghi, C; Boschi, S; Costa, FV; Mussi, A, 1990)
"To evaluate the participation of the renin-angiotensin system in sustaining hypertension, we administered the specific dipeptide renin inhibitor enalkiren (A-64662) to 18 patients with essential hypertension."3.68Assessment of renin dependency of hypertension with a dipeptide renin inhibitor. ( Boger, RS; Essinger, I; Glassman, HN; Luther, R; Neutel, JM; Weber, MA, 1990)
"The plasma aldosterone (A) and desoxycorticosterone (DOCS) levels were measured in 10 patients with primary aldosteronism and in 2 subgroups with low-renin hypertensive disease (LRHD): (1) those with normal adrenal glands++ (n - 11) and (2) those with structural changes in the cortex (n - 11)."3.68[Plasma mineralocorticoids--aldosterone and desoxycorticosterone-- in patients with"low-renin"arterial hypertension]. ( Bulkina, OS; Gorbacheva, ON; Levitskaia, IuV; Obtrakht, NV; Sokolova, RI; Ustinova, SE, 1990)
"We examined the salt sensitivity of blood pressure in angiotensin II (ANG II)-induced hypertension."3.68Salt sensitivity in hypertensive rats with angiotensin II administration. ( Ando, K; Fujita, T; Sato, Y, 1990)
"The effect of the direct renin inhibitor enalkiren (Abbott Laboratories) was examined in 8 healthy patients with essential hypertension."3.68Effects of renin inhibition in systemic hypertension. ( Anderson, PW; Boger, RS; Do, YS; Horton, R; Hsueh, WA; Luther, RR; Schambelan, M, 1990)
"Hypertension in patients with NIDDM is frequently salt-sensitive, which may be due to sodium retention and enhanced vascular reactivity to angiotensin II."3.68Salt-sensitive blood pressure and exaggerated vascular reactivity in the hypertension of diabetes mellitus. ( Corry, D; Trujillo, A; Tuck, M, 1990)
"There is evidence of crucial central nervous system involvement in the pathogenesis of mineralocorticoid-excess salt hypertension, as well as data indicating that corticosterone is the predominant ligand for the type I adrenocorticoid receptor in the brain."3.68ICV infusion of corticosterone antagonizes ICV-aldosterone hypertension. ( Fort, C; Gómez-Sánchez, EP; Thwaites, D; Venkataraman, MT, 1990)
"Initial experiments demonstrated that a 1-h infusion of 10 ng/min angiotensin II (ANG II) into rats causes an increase in plasma aldosterone concentration (PAC) and that chronic administration of aldosterone alone to rats on increased sodium intake causes hypertension."3.68Role of aldosterone in angiotensin II-induced hypertension in rats. ( Fink, GD; Kanagy, NL; Pawloski, CM, 1990)
"Ten male patients with essential hypertension were studied on a constant diet (100 mEq of sodium daily) while on placebo, immediately following a 20-mg oral dose of nitrendipine, and during 1 week of nitrendipine therapy (10 mg twice daily)."3.67Renal effects of nitrendipine monotherapy in essential hypertension. ( Barrett, JD; Eggena, P; Golub, MS; Sambhi, MP; Thananopavarn, C, 1984)
"The converting enzyme inhibitor enalapril, in single daily doses of 10 to 40 mg, was given to 20 hypertensive patients with renal artery stenosis."3.67Enalapril in treatment of hypertension with renal artery stenosis. Changes in blood pressure, renin, angiotensin I and II, renal function, and body composition. ( Brown, JJ; Cumming, AM; Davies, DL; East, BW; Hodsman, GP; Lever, AF; Morton, JJ; Murray, GD; Robertson, JI, 1984)
"Enalapril lowers blood pressure both acutely and during long-term therapy in patients with essential hypertension."3.67Plasma enalapril levels and hormonal effects after short- and long-term administration in essential hypertension. ( Casley, D; Cubella, R; Jackson, BJ; Johnston, CI; Larmour, I, 1984)
"Forty to fifty percent of patients with essential hypertension are unable to modify their adrenal and renal vascular responses to angiotensin II with changes in sodium intake."3.67Converting enzyme inhibitors normalize the reduced adrenal responsiveness to angiotensin II in essential hypertension. ( Hollenberg, NK; Williams, GH, 1984)
"The dependence of arteriolar vasoconstrictor tone on the activity of Na+,K+-ATPase was studied in 17 normotensive subjects (NT) and 28 patients with essential hypertension (EH) by measuring the response in forearm blood flow and vascular resistance to intraarterial infusion of the Na+,K+-ATPase inhibitor ouabain."3.67Forearm vasoconstrictor response to ouabain: studies in patients with mild and moderate essential hypertension. ( Bolli, P; Bühler, FR; Hulthén, UL; Kiowski, W, 1984)
" Furthermore, acute and chronic administrations of clonidine were used to determine a participation of the sympathetic nervous system in the maintenance of hypertension in these patients."3.67Plasma catecholamines and autonomic nervous system function in patients with early renal insufficiency and hypertension: effect of clonidine. ( Campese, VM; Levitan, D; Massry, SG; Romoff, M, 1984)
"The converting-enzyme inhibitor captopril (25-50 mg orally every 6 h for 66 h) was used to dissociate the circulating levels of angiotensin II (ANG II) from changes in sodium balance in 11 patients with normal renin essential hypertension on 10 mmol of sodium/day intake."3.67Captopril enhances vascular and adrenal responsiveness to angiotensin II in essential hypertension. ( Dluhy, RG; Gordon, MB; Hollenberg, NK; Koletsky, RJ; LeBoff, MS; Moore, TJ; Williams, GH, 1984)
"Treatment of fifteen patients with essential hypertension over four weeks using the beta 1-adrenoceptor blocking agent, metoprolol, resulted in a decrease in 24 h urinary excretion of kallikrein and aldosterone along with a decrease in plasma renin activity."3.67Effect of metoprolol on 24-hour urinary excretion of adrenal steroids and kallikrein in patients with essential hypertension. ( Fritschka, E; Gotzen, R; Kittler, R; Schöneshöfer, M, 1984)
"Timolol, a non-cardioselective beta-blocking agent, was administered orally after 2 weeks of placebo to 14 patients with essential hypertension for 8 weeks following 1-4 weeks of dose-ranging period."3.67Effects of timolol on blood pressure, systemic hemodynamics, plasma renin activity, and glomerular filtration rate in patients with essential hypertension. ( Bedogna, V; Fabris, A; Gammaro, L; Maschio, G; Ortalda, V; Tessitore, N; Valvo, E, 1984)
"Potassium balance was followed in 12 subjects with hypertension during treatment either with timolol and hydrochlorothiazide or with timolol, hydrochlorothiazide, and amiloride."3.67Thiazide-induced potassium loss not prevented by beta blockade. ( Steiness, E, 1984)
"Captopril, an orally active angiotensin-converting enzyme inhibitor, was administered to 15 patients with essential hypertension."3.67Acute effect of captopril on serum lipid peroxides level in hypertensive patients. ( Fukuchi, S; Gotoh, M; Mizuno, K, 1984)
"Studies were carried out in 15 patients with renal insufficiency and hypertension to compare the long-term effects of methyldopa and propranolol on renal hemodynamics."3.67Comparison of long-term renal hemodynamic effects of methyldopa and propranolol in patients with hypertension and renal insufficiency. ( Alterman, L; Bank, DE; Bank, N; Lowenstein, I; Zelen, R, 1984)
"Blood pressure, plethysmographically determined muscle blood flow in the calf at rest and during maximal dilatation, plasma renin activity, angiotensin II and plasma and urinary aldosterone were determined in normotensive men with a positive family history of hypertension (n = 17) and in an age- and weight-matched control group (n = 15) during usual sodium intake and after four weeks of increased salt intake."3.67Calf muscle haemodynamics and the renin-angiotensin-aldosterone system in normotensive subjects with a familial predisposition to hypertension: changes during increased salt intake. ( Andersson, OK; Aurell, M; Berglund, GL; Gudmundsson, O; Wikstrand, JM, 1984)
"Aldosterone responses to posture and the dopamine antagonist, metoclopramide, were studied in seven normotensive controls and 12 patients with essential hypertension."3.67Enhanced response of plasma aldosterone to metoclopramide in essential hypertension. ( Eshkol, A; Lunenfeld, B; Rosenthal, T; Sowers, JR; Stern, N; Tuck, M, 1984)
"The hypothesis that pregnancy induced hypertension (PIH) is associated with abnormal physiological control of plasma renin activity (PRA) was tested by studying the effects of graded infusion of angiotensin II (ANG II) on PRA, plasma aldosterone (PA), and blood pressure in normal pregnancy, PIH, non-pregnant women in luteal and follicular phase of the menstrual cycle, and males."3.67Failure of angiotensin II to reduce plasma renin activity in hypertensive pregnant women. ( Alcazar, JM; Garcia-Robles, R; Hammond, TG; Knox, FG; Paya, C; Rodicio, J; Romero, JC; Ruilope, L; Sancho-Rof, J, 1984)
"To compare the effect of amiloride with that of oral potassium chloride (KCl) in hypokalemia, metabolic balance studies were carried out in hospitalized subjects with mild hypertension without edema who developed negative potassium balance after 4 days on hydrochlorothiazide (HCTZ)."3.67Oral potassium chloride and amiloride in hydrochlorothiazide-induced potassium loss. ( Barr, J; Chan, L; Maronde, RF; Spencer, CA; Vlachakis, ND, 1984)
"In patients with mild hypertension, flurbiprofen in a dose of 100 mg daily for 7 days attenuated the hypotensive effect of a single dose of propranolol 80 mg but not of atenolol 100 mg."3.67Flurbiprofen interaction with single doses of atenolol and propranolol. ( Hawksworth, GM; McLean, I; Petrie, JC; Webster, J, 1984)
"The responsiveness of plasma aldosterone to the infusion of angiotensin II at dose rates of 2, 4, and 10 ng/kg X min was assessed in 11 normal subjects and 13 patients with mild essential hypertension before and after 4 weeks of treatment with the sympatholytic agent debrisoquine."3.67Relationship between plasma aldosterone and angiotensin II before and after noradrenergic inhibition in normal subjects and patients with mild essential hypertension. ( Beretta-Piccoli, C; Bianchetti, MG; Boehringer, K; Link, L; Morton, JJ; Weidmann, P, 1984)
"A 46-year-old woman with hypertension, normokalemia, suppressed renin, normal catecholamines, and a left adrenal mass on the CT scan was found to have excessive 18-hydroxycorticosterone (18-OHB) and normal aldosterone levels in plasma, both of which responded poorly to sodium restriction and angiotension II, and supranormally to ACTH."3.67Adrenal adenoma with 18-hydroxycorticosterone excess and hypertension: a variant of aldosteronomas. ( Azukizawa, S; Hosojima, H; Imaizumi, N; Kigoshi, T; Morimoto, S; Uchida, K; Yamamoto, I, 1984)
"A single dose of doxazosin, a long-acting postsynaptic alpha 1-adrenoceptor antagonist, was administered to seven patients with essential hypertension."3.67Antihypertensive effects and pharmacokinetics of single and consecutive administration of doxazosin in patients with mild to moderate essential hypertension. ( Kaneko, Y; Miyajima, E; Miyakawa, T; Shionoiri, H; Takagi, N; Umemura, S; Yasuda, G; Yoshimura, H, 1987)
" For this purpose, in a group of 11 patients with essential hypertension we have compared the blood pressure lowering effects of a single oral dose of nifedipine before (100 mmol Na+/day and 40 mmol K+/day) and after sodium depletion (20 mmol Na+/day and 40 mmol K+/day: each period was of 6-8 day duration)."3.67Effects of different sodium intakes on the antihypertensive and renal effects of single oral doses of nifedipine in hypertensive patients. ( Bolla, G; Cuspidi, C; Gradnik, R; Leonetti, G; Rupoli, L; Sangiorgio, P; Zanchetti, A, 1987)
"The principal aim of this study was to investigate the effects of ketanserin on peripheral vascular pressor mechanisms in nine patients with essential hypertension, including an assessment of the responsiveness to intravenous infusions of the alpha 1-adrenergic agonist, phenylephrine, and the nonadrenergic vasoconstrictor, angiotensin II."3.67Effects of ketanserin on peripheral vascular pressor mechanisms in essential hypertension. ( Donnelly, R; Elliott, HL; Reid, JL, 1988)
" Eight patients with essential hypertension were challenged with an infusion of 32 mmol of potassium chloride in saline before and after control of their blood pressure by the angiotensin converting-enzyme (ACE) inhibitor enalapril."3.67Effect of angiotensin converting-enzyme inhibition on potassium-mediated aldosterone secretion in essential hypertension. ( Barnes, JN; Drew, PJ; Furniss, SS; Goodwin, FJ; Holly, JM; Knight, AR; Skehan, JD, 1985)
"Glomerular filtration rate (GFR) and tubular function were measured by means of the lithium clearance technique in 14 patients with renovascular hypertension (RVH) and eight patients with essential hypertension (EH) before and after oral administration of captopril 25 mg."3.67Abnormal glomerular and tubular function during angiotensin converting enzyme inhibition in renovascular hypertension evaluated by the lithium clearance method. ( Amdisen, A; Danielsen, H; Eiskjaer, H; Hansen, HH; Jensen, FT; Jespersen, B; Madsen, B; Nielsen, HK; Pedersen, EB; Sørensen, SS, 1989)
"In patients with essential hypertension and healthy controls, plasma levels of atrial natriuretic peptide (ANP), angiotensin II (Ang II), aldosterone (Aldo), arginine vasopressin (AVP) and urinary excretion of prostaglandin E2 (PGE2) were measured under basal conditions, and before and after acute volume expansion with a 2."3.67Atrial natriuretic peptide and exaggerated natriuresis during acute hypertonic volume expansion in essential hypertension. ( Amdisen, A; Danielsen, H; Pedersen, EB; Sørensen, SS, 1989)
"The author reviews contemporary views on the pathogenetic participation of selected humoral factors (of the renin-angiotensin-aldosterone system, natriuretic hormone and atrial natriuretic factor) in the development of arterial hypertension in humans."3.67[Humoral mechanisms in the pathogenesis of arterial hypertension with emphasis on the renin-angiotensin-aldosterone system and natriuretic substances]. ( Horký, K, 1989)
"The relationship between atrial natriuretic factor (ANF), the renin-aldosterone axis, and blood pressure reduction with weight loss was investigated in 18 obese subjects (five hypertensive and 13 normotensive) placed on a 12-week, low-sodium (40 mmol), weight-reducing diet."3.67Weight reduction decreases atrial natriuretic factor and blood pressure in obese patients. ( McMurray, RW; Vesely, DL, 1989)
"Patients with normal- or high-renin non-modulating essential hypertension fail to shift their adrenal sensitivity on a low sodium diet in response to an infusion of angiotensin II (Ang II)."3.67Prolonged converting enzyme inhibition in non-modulating hypertension. ( Dluhy, RG; Hollenberg, NK; Smith, K; Taylor, T; Williams, GH, 1989)
"To elucidate mechanisms of angiotensin II (Ang II)-related hypertension, we infused angiotensin (76 ng/min s."3.67Angiotensin-induced hypertension in the rat. Sympathetic nerve activity and prostaglandins. ( Demmert, G; Ganten, D; Kühn, R; Luft, FC; Rohmeiss, P; Sterzel, RB; Unger, T; Wilcox, CS, 1989)
" All animals were treated from 4 wk of age with captopril (100 mg/kg/day in drinking water) to prevent development of hypertension so that changes in responsiveness could not be attributed to disparate base-line blood pressures or to hypertension-induced injury of the cardiovascular system."3.67Enhanced slow-pressor response to angiotensin II in spontaneously hypertensive rats. ( Jackson, EK; Li, P, 1989)
" Parameters measured included blood pressure, blood chemistry (serum creatinine, uric acid, blood urea nitrogen, blood glucose total cholesterol, and electrolytes), plasma renin activity, and plasma aldosterone concentration."3.67Effects of nicardipine on blood pressure and renal function in elderly hypertensive patients with renal dysfunction. ( Saruta, T, 1989)
" In this study, nifedipine was administered in doses of 40 to 80 mg/day to 14 patients with essential hypertension, and its hemodynamic effects were evaluated by non-invasive methods, and its effect on glucose metabolism by an arginine infusion test."3.67Hemodynamic and endocrine effects of acute and chronic administration of nifedipine. ( Chiasson, JL; Larochelle, P; Parent, R, 1989)
"Nine hypertensive patients with mild to moderate renal dysfunction were entered into a protocol to assess the blood pressure, humoral and renal effects of the angiotensin converting enzyme inhibitor, Benazepril (CGS14824A, 2 to 20 mg twice daily) in patients with hypertension and moderate renal insufficiency (mean creatinine clearance 56 ml/min/1."3.67Effect of benazepril monotherapy in subjects with hypertension associated with renal dysfunction. ( Bauer, JH; Lau, A; Reams, GP, 1989)
"We studied the effects of intravenous injections of the renin inhibitor A-64662 on blood pressure, plasma renin activity (PRA), angiotensin II (Ang II) and aldosterone levels in patients with essential hypertension."3.67Renin inhibition with A-64662: effect on blood pressure and hormonal response in man. ( Bauer, JH; Bursztyn, M; Gavras, H; Gavras, I; Melby, JC; Tifft, CP, 1989)
"Effects of a single administration of captopril on plasma and urinary vasopressin (AVP) were examined in 8 normotensive (NT) female volunteers, 17 patients with essential hypertension (EHT) and 2 patients with primary aldosteronism (PA)."3.67Effect of single-administration captopril on plasma and urinary vasopressin in normotensive subjects and patients with essential hypertension and primary aldosteronism. ( Fujishima, M; Kimura, Y; Muratani, H; Nakao, Y; Takishita, S; Tomita, Y; Tsuchihashi, T; Ueno, M, 1989)
" Nonmodulating hypertension in part is characterized by decreased aldosterone secretion in response to angiotensin II (AII) as well as a decreased natriuretic response to a saline load."3.67The role of dopamine in nonmodulating hypertension. ( Conlin, PR; Gordon, MS; Hollenberg, NK; Steunkel, CA; Williams, GH, 1989)
"In 16 patients with essential hypertension the effects of enalapril 20 mg once daily were compared with those of atenolol 50 mg once daily, with the two drugs in combination and with placebo using a double-blind cross-over design with allocation of treatment order by randomised Latin squares."3.67Enalapril and atenolol in essential hypertension: attenuation of hypotensive effects in combination. ( Bune, AJ; Cain, MD; Chalmers, JP; Morris, MJ; Russell, AE; Southgate, DO; West, MJ; Wing, LM, 1988)
"The effects of ovine corticotropin releasing factor (o-CRF) on plasma aldosterone, 18-OH-corticosterone (18-OHB), plasma adrenocorticotropin (ACTH) and cortisol were determined in eight patients with primary aldosteronism, six with aldosterone-producing adenoma (APA) and two with idiopathic hyperaldosteronism (IHA)."3.67Effects of corticotropin-releasing factor (CRF) on aldosterone and 18-hydroxycorticosterone in essential hypertension and primary aldosteronism. ( Ikeda, M; Koshida, H; Matsubara, T; Miyamori, I; Morise, T; Okamoto, S; Takeda, R; Takeda, Y; Vecsei, P; Yasuhara, S, 1987)
" Fenoldopam, the first selective DA1-receptor agonist that can be administered to man, was infused intravenously in 17 patients with essential hypertension (mean blood pressure 152/101 mm Hg)."3.67Augmentation of renal blood flow and sodium excretion in hypertensive patients during blood pressure reduction by intravenous administration of the dopamine1 agonist fenoldopam. ( Douglas, FL; Frederickson, ED; Goldberg, LI; McCoy, CE; Murphy, MB; Weber, RR, 1987)
"This study was designed to examine the mechanisms that contribute to the chronic hypotensive effects of verapamil during angiotensin II-induced hypertension."3.67Chronic hypotensive effects of verapamil in angiotensin hypertension are steroid independent. ( Lohmeier, TE; Montani, JP; Rushing, EL; Smith, MJ, 1989)
"Thirteen patients with hypertension and normal renal function received nitrendipine, a calcium entry blocker."3.67Nitrendipine, a calcium-entry blocker. Renal and humoral effects in human arterial hypertension. ( Bravo, EL; Fouad, FM; Pedrinelli, R; Tarazi, RC; Textor, SC, 1986)
"To study the effects of Ca antagonists on hypertension induced cardiac and vascular hypertrophy, diltiazem, at the doses of 30 and 60 mg/kg, p."3.67[Effects of diltiazem on developing blood pressure and accompanying cardiac and vascular hypertrophy in SHR]. ( Inamasu, M; Iwasaki, HO; Morita, T; Nagao, T; Narita, H, 1985)
" These studies were performed in patients with essential hypertension who were maintained on a constant sodium intake (100 mmol/day), before and after 5 days of treatment with ibopamine, an orally active dopamine analogue."3.67Dopaminergic control of aldosterone secretion is not mediated by atrial natriuretic factor in patients with essential hypertension. ( Ambrosi, B; Ardeleani, G; Ferraris, P; Morganti, A; Quorso, P; Sala, C; Venegoni, P; Zanchetti, A, 1988)
"To assess the pathophysiological role of atrial natriuretic factors in mineralocorticoid hypertension, we studied the effects of chronic infusion of synthetic atrial natriuretic factor on blood pressure and sodium-water excretion in rats with aldosterone salt-induced hypertension."3.67Effects of chronically administered atrial natriuretic factor in aldosterone-infused hypertensive rats. ( Abe, K; Hiwatari, M; Kanazawa, M; Kohzuki, M; Saito, T; Saso, S; Yasujima, M; Yoshida, K; Yoshinaga, K, 1988)
" The present study evaluated plasma beta-endorphin, ACTH, cortisol, and aldosterone levels in patients with IHA (n = 10), aldosterone-producing adenomas (n = 4), essential hypertension (n = 11), and normal subjects (n = 10)."3.67Plasma beta-endorphin levels in primary aldosteronism. ( Berelowitz, B; Griffing, GT; Hudson, M; Manson, JA; McIntosh, T; Melby, JC; Salzman, R, 1985)
"Based on their previous observations of the stimulating action of verapamil on the secretory reserve of cortisol after one-week oral administration to healthy volunteers, the author investigated the effect of this calcium entry blocker on the adrenocortical function (cortisol and aldosterone secretion) during therapeutic administration to patients with mild arterial hypertension and normotensive patients suffering from Raynaud's syndrome."3.67The effect of long-term verapamil treatment on the secretion of cortisol and aldosterone in subjects with normal and high blood pressure. ( Zofková, I, 1985)
"The acute antihypertensive effect of a new long-acting oral angiotensin I-converting enzyme (ACE) inhibitor, enalapril maleate, was assessed in 20 hypertensive patients, of whom 14 had essential hypertension, 4 had renovascular hypertension, one had hypertension associated with chronic renal failure, and one had primary aldosteronism."3.67[The acute effects of the new angiotensin I-converting enzyme inhibitor, enalapril maleate, on blood pressure, plasma renin, aldosterone and kinins in hypertensive patients]. ( Fukuchi, S; Gotoh, M; Hashimoto, S; Kunii, N; Mizuno, K, 1985)
"The purpose of this study was to evaluate the natriuretic effect and renal haemodynamic changes induced by enalapril in patients with essential hypertension."3.67Natriuretic effect and changes in renal haemodynamics induced by enalapril in essential hypertension. ( Brito, M; Gilbert, HB; Giménez, M; Marcó, E; Moledo, LI; Raffaele, P; Sánchez, RA, 1985)
"In 15 patients with mild-to-moderate essential hypertension a new orally active angiotensin converting enzyme inhibitor, 1-(D-3-acetylthio-2-methylpropanoyl)-L-prolyl-L-phenylalanine (Alacepril), was administered with a single oral dose of 50 mg to evaluate its antihypertensive effect."3.67Acute effects of the new oral angiotensin converting enzyme inhibitor 1-(D-3-acetylthio-2-methylpropanoyl)-L-prolyl-L-phenylalanine (Alacepril) in essential hypertension. ( Fukuchi, S; Hashimoto, S; Kunii, N; Mizuno, K; Niimura, S; Tani, M; Watari, H; Yabe, R, 1985)
"We evaluated the effect of additional chlorthalidone therapy on blood pressure and body fluid volumes in 10 patients with essential hypertension who did not respond to chronic converting enzyme inhibition with enalapril."3.67Changes in blood pressure and body fluid volumes during diuretic therapy in patients with essential hypertension who receive enalapril. ( Geyskes, GG; Mees, EJ; Roos, JC; van Schaik, BA, 1986)
"To investigate whether dopamine plays a role in the regulation of aldosterone secretion during long-term blockade of the renin-angiotensin system, we studied the effect of metoclopramide, a competitive antagonist of dopamine, in 6 patients with essential hypertension chronically treated with the angiotensin converting enzyme inhibitor enalapril."3.67Dopaminergic control of aldosterone secretion in hypertensive patients chronically treated with an angiotensin converting enzyme inhibitor. ( Brunner, HR; Gomez, HJ; Nussberger, J; Schaller, MD; Waeber, B, 1986)
" In its severe form, hypertension and hypokalemic alkalosis are present, owing to increased secretion of the sodium-retaining corticoids, corticosterone and deoxycorticosterone."3.67Cortisol resistance in man. ( Brandon, DD; Chrousos, GP; De Vroede, MM; Lipsett, MB; Loriaux, DL; Tomita, M, 1986)
"The time course of the blood pressure lowering effect and the dose-response relationship of the new angiotensin converting enzyme inhibitor ramipril (HOE 498) were studied in 8 patients, with essential hypertension."3.67Studies on the antihypertensive effect of single doses of the angiotensin converting enzyme inhibitor ramipril (HOE 498) in man. ( Böhm, RO; Rahn, KH; van Baak, MA, 1986)
"The angiotensin converting enzyme (ACE) inhibitor captopril proved to be an effective antihypertensive drug during a 5-year follow-up study of patients with severe hypertension who had been resistant to a triple-drug regimen."3.67[Results of a 5-year study with captopril in patients with severe therapy-resistant hypertension]. ( Scheler, F; Schoel, G; Schrader, J, 1986)
"Nifedipine, in a slow release preparation, was given at a mean daily dosage of 47 +/- 4 mg to 12 patients with severe hypertension in whom arterial pressure was not satisfactorily controlled (mean blood pressure, 172 +/- 6/111 +/- 4 mmHg) by the association of a converting enzyme inhibitor and a diuretic."3.67Effect of nifedipine in hypertension not controlled by converting enzyme inhibitor and diuretic. ( Mimran, A; Ribstein, J, 1986)
"Thirteen subjects with essential hypertension controlled on oral enalapril (20 mg/day) therapy were entered into a protocol to assess serially 24-hour blood pressure, the renin-angiotensin-aldosterone system, angiotensin-converting enzyme activity, and plasma and urine enalaprilat drug levels, following both chronic oral administration of enalapril and its replacement with intravenous enalaprilat."3.67Enalaprilat: an intravenous substitute for oral enalapril therapy. Humoral and pharmacokinetic effects. ( Bauer, JH; Lal, SM; Reams, GP; Whalen, JJ, 1986)
"0] octane-3-carboxylic acid (ramipril, Hoe 498) were investigated in 10 patients with essential hypertension (WHO stage I or II)."3.67Humoral and blood pressure effects of the angiotensin converting enzyme inhibitor ramipril in essential hypertension. ( Distler, A; Eckert, HG; Haller, H; Irmisch, R; Lenz, T; Metzger, H; Meyer-Sabellek, W; Philipp, T; Tansey, MJ; Wilp, C, 1986)
"Captopril effects were studied in 27 patients with second-stage essential hypertension following administration of a single 25 mg oral dose of the drug."3.67[Mechanisms of the hypotensive action of captopril in essential hypertension]. ( Chernova, NA; Parfenova, EV; Uchitel', IA; Ustinova, SE; Zhukova, IM, 1986)
"Hyperresponsiveness of plasma aldosterone to metoclopramide (MCP) was found in the patients with secondary aldosteronism."3.67[Influence of endogenous renin-angiotensin system on plasma aldosterone responsiveness to metoclopramide]. ( Iwasaki, Y, 1987)
"Plasma renin activity (PRA) and plasma aldosterone concentration (PAC) were measured in 19 cases with primary aldosteronism (PA) and 72 with essential hypertension (EHT) to differentiate the two disorders in the following conditions: after overnight recumbency (basal state) and after oral administration of captopril."3.67Single oral administration of captopril may not bring an improvement in screening of primary aldosteronism. ( Abe, I; Fujishima, M; Kawasaki, T; Kawazoe, N; Muratani, H; Takishita, S; Tomita, Y; Tsuchihashi, T; Ueno, M, 1987)
" Values for serum and urinary calcium, phosphorus, magnesium and electrolytes, creatinine clearance, plasma immunoreactive parathyroid hormone, and serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D were similar in both study groups on each diet."3.67Normal vitamin D and mineral metabolism in essential hypertension. ( Bell, NH; Epstein, S; Hughes, GS; Margolius, HS; Oexmann, MJ, 1988)
"The role of central pressor mechanisms in the maintenance of blood pressure in six hypertensive patients with angiographically proven unilateral renal artery stenosis was investigated by studying the haemodynamic and hormonal responses before and after central sympathetic blockade with clonidine."3.67Cardiovascular and neurohormonal changes following central sympathetic blockade with clonidine in human unilateral renal artery stenosis. ( Kooner, JS; Mathias, CJ; Peart, S, 1988)
"The magnitude of captopril hypotensive effect, and variation in renin-angiotensin-aldosterone and kallikrein-kinin parameters were examined in patients with advanced essential hypertension in the presence of normal and low plasma renin activity."3.67[Changes in the indicators of the renin-angiotensin-aldosterone system, kallikrein-kinin system and arterial blood pressure in elderly patients with essential hypertension treated with captopril]. ( Beuer, E; Brozovskiĭ, KKh; Faulhaber, H; Gurke, R; Khartrodt, V, 1988)
"In 35 initially normotensive patients with chronic glomerulonephritis and lupus nephritis (including 27 patients with nephrotic syndrome; NS), blood pressure (BP), urinary sodium excretion, plasma renin activity (PRA), plasma aldosterone level (PA), urinary aldosterone excretion (Au and blood volume were measured before and during prednisolone treatment."3.67Steroid-induced hypertension in patients with nephrotic syndrome. ( Klepikov, PV; Kutyrina, IM; Tareyeva, IE, 1988)
"We investigated the effect of an orally administered, long-acting, beta-adrenergic blocking agent, penbutolol, on the circadian rhythm of blood pressure (BP) and heart rate (HR), and plasma renin activity (PRA), aldosterone (PA) and cortisol (PC) levels in hospital patients with essential hypertension validated by a chronobiological inferential statistic method."3.67Effect of penbutolol on circadian blood pressure, and renin, aldosterone and cortisol levels in patients with essential hypertension. ( Bianconi, M; degli Uberti, EC; Margutti, A; Pansini, R; Portaluppi, F; Rossi, R; Teodori, V; Trasforini, G, 1988)
"The validity of the captopril test for primary aldosteronism (PA) was tested in patients with surgically verified PA (n = 12) or essential hypertension (EHT, n = 20) with different levels of sodium intakes."3.67Effects of sodium intake on the captopril test for primary aldosteronism. ( Iwaoka, T; Naomi, S; Sato, T; Umeda, T, 1987)
" Lasilactone, a new combination diuretic (furosemide 20 mg and spironolactone 50 mg) was evaluated in 30 patients with mild-to-moderate essential hypertension."3.67Efficacy and safety of lasilactone, a new combination diuretic, in essential hypertension. ( Birbari, AE; Daouk, MM; Mukaddam-Daher, S, 1987)
"In order to evaluate whether changes in the plasma concentration of aldosterone (PA) following the administration of captopril, an inhibitor of angiotensin-converting enzyme, will establish the diagnosis of primary aldosteronism we have used this test in 9 healthy subjects and in 22 patients with various forms of hypertension, including 5 patients with primary aldosteronism due to idiopathic adrenal hyperplasia (n = 4) or aldosterone-producing adenoma (n = 1)."3.67[Detection of primary aldosteronism using the captopril test]. ( Graninger, W; Nowotny, P; Pirich, K; Vierhapper, H; Waldhäusl, W, 1987)
"We studied natriuresis during central hypervolaemia by immersing eight normal subjects and eight patients with uncomplicated essential hypertension up to the neck in water, either in the absence (study 1) or presence (study 2) of dopamine blockade by metoclopramide."3.67Dopamine blockade abolishes the exaggerated natriuresis of essential hypertension. ( Biggi, A; Coruzzi, P; Musiari, L; Novarini, A; Ravanetti, C, 1987)
"Oral administration of felodipine to 10 patients with mild essential hypertension acutely reduced the brachial artery pressure by 15/13mm Hg."3.67Effects of felodipine and metoprolol on blood pressure, plasma renin, angiotensin II, aldosterone and catecholamines in hypertensive patients. ( Amery, A; De Schaepdryver, A; Fagard, R; Lijnen, P; Moerman, E; Staessen, J, 1987)
"The immediate effects of intravenous diltiazem effects and short-term (4 weeks) of the oral drug on systemic and regional hemodynamics, cardiac structure, and humoral responses were evaluated by previously reported methods in nine patients with mild-to-moderate essential hypertension and in one patient with primary aldosteronism."3.67Immediate and short-term hemodynamic effects of diltiazem in patients with hypertension. ( Amodeo, C; Frohlich, ED; Kobrin, I; Messerli, FH; Ventura, HO, 1986)
"The effect of angiotensin converting enzyme inhibition by captopril (CAP) on serum potassium (SK) changes was studied during a three-hour glucose tolerance test (GTT) in recumbent and upright positions in 16 patients with drug-resistant hypertension."3.67Interplay of various factors in glucose-induced hyperkalemia during captopril treatment. ( Bános, C; Gercsák, G; Radó, JP, 1986)
"The cardiovascular pressor responses to a stepwise increase in plasma norepinephrine or angiotensin II concentrations, induced by infusions, were studied in 23 normotensive subjects with a negative and 25 with a positive family history of essential hypertension."3.67Blood pressure control in normotensive members of hypertensive families. ( Beretta-Piccoli, C; Bianchetti, MG; Ferrier, C; Weidmann, P, 1986)
"The influence of long-term nifedipine treatment on body fluid compartments, renal function, the renin-angiotensin system, and the adrenergic system was studied in 18 patients with essential hypertension."3.67Lack of effect of nifedipine on counterregulatory mechanisms in essential hypertension. ( Bruun, NE; Hartling, OJ; Ibsen, H; Moelbak, AG; Nielsen, F; Nielsen, MD, 1986)
"Plasma renin activity (PRA) and plasma aldosterone concentration (PAC) were measured in 19 cases with primary aldosteronism (PA) and in 72 with essential hypertension (EHT) to differentiate the two disorders during the following conditions on normal salt diet: after overnight recumbency (basal state) and 2 hours after oral administration of 25 mg of captopril."3.67Is single oral administration of captopril beneficial in screening for primary aldosteronism? ( Abe, I; Kawasaki, T; Kawazoe, N; Kimura, Y; Muratani, H; Takishita, S; Tomita, Y; Tsuchihashi, T; Ueno, M; Uezono, K, 1986)
"The effect of 8 weeks treatment with the calcium antagonist felodipine--a new long-acting dihydropyridine derivative--in a dose of 10 mg twice daily was studied in 10 male patients with essential hypertension, WHO grade I-II, aged 25-62 years."3.67The effect of 8 weeks treatment with the calcium antagonist felodipine on blood pressure, heart rate, working capacity, plasma renin activity, plasma angiotensin II, urinary catecholamines and aldosterone in patients with essential hypertension. ( Hökfelt, B; Hulthén, UL; Katzman, PL, 1986)
"The effects of a calcium antagonist [Nicardipine hydrochloride (NH)] on the prostaglandin [prostaglandin E2 (PGE2), and 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha)] and thromboxane B2 levels in the blood and urine were examined in 6 patients with essential hypertension following intravenous infusion of NH for 120 minutes."3.67Effects of intravenous administration of a calcium antagonist on prostaglandins and thromboxane in plasma and urine in humans. ( Fukuda, N; Hatano, M; Honda, M; Izumi, Y; Manabe, R; Minato, M; Watanabe, M, 1986)
"The effect of exogenous angiotensin II on plasma renin activity (PRA), plasma renin concentration (PRC) and plasma aldosterone (PA) was investigated in a group of 8 patients with essential hypertension after one year of captopril therapy."3.67Effect of exogenous angiotensin II infusion after one year of captopril therapy in essential hypertension. ( Hammond, TG; Miranda, B; Robles, RG; Rodicio, JL; Romero, JC; Ruilope, LM; Sancho, J, 1986)
"7 years, with systemic systolic hypertension were studied before and after 1 month of therapy with oral hydrochlorothiazide, 50 mg/day."3.67Systemic systolic hypertension in the elderly: correlation of hemodynamics, plasma volume, renin, aldosterone, urinary metanephrines and response to thiazide therapy. ( Dunsky, MH; Hill, NE; Mookherjee, S; Smulyan, H; Vardan, S; Warner, RA, 1986)
"Oral administration of felodipine to 10 patients with mild essential hypertension acutely reduced systemic vascular resistance (SVR) by 40% after 30 min."3.67Acute haemodynamic and humoral responses to felodipine and metoprolol in mild hypertension. ( Amery, A; Fagard, R; Lijnen, P; Moerman, E; Staessen, J, 1987)
"Plasma concentrations of arginine vasopressin (AVP), angiotensin II (AII), aldosterone (Aldo), urinary output (V), osmolar clearance (Cosm), free water clearance (CH2O), fractional excretions of sodium (FENa) and potassium (FEK), urinary sodium excretion rate (U-Na) and serum potassium (S-K) were determined in 9 patients with essential hypertension (group I) and 13 normotensive healthy control subjects (group II) before and three times during the first 4 hours after an intravenous injection of 40 mg of furosemide."3.67Abnormal vasopressin and aldosterone response to furosemide in essential hypertension. ( Danielsen, H; Madsen, M; Pedersen, EB; Sørensen, SS; Thomsen, OO, 1986)
"This study assessed renal sodium handling in a group of patients with essential hypertension in whom control of the renal blood supply and aldosterone release by angiotensin II is abnormal ("non-modulating") because of recent evidence that these patients have sodium-sensitive hypertension."3.67Abnormal renal sodium handling in essential hypertension. Relation to failure of renal and adrenal modulation of responses to angiotensin II. ( Hollenberg, NK; Moore, T; Rabinowe, S; Redgrave, J; Shoback, D; Williams, GH, 1986)
"Plasma aldosterone, 18-hydroxycorticosterone (18-OH-B), 18-hydroxydeoxycorticosterone (18-OH-DOC), corticosterone, cortisol and prolactin levels were determined during an angiotensin II infusion at increasing rates both with and without a simultaneous infusion of dopamine in seven normotensive subjects, in ten patients with essential hypertension, and in ten patients with primary aldosteronism."3.67Dopamine reduces aldosterone and 18-hydroxycorticosterone response to angiotensin II in patients with essential low-renin hypertension and idiopathic hyperaldosteronism. ( Lorenz, R; von Werder, K; Weber, PC; Witzgall, H, 1985)
"The effects of chronic dietary salt-loading and nifedipine therapy on hypertension-prone (SBH), -resistant (SBN) and parental (SB) Sabra rats were investigated."3.67Salt-induced hypertension in the 'Sabra' rat strain: influence of nifedipine treatment. ( Ben-Ishay, D; Ebsen, W; Garthoff, B; Kazda, S; Luckhaus, G, 1985)
"The effects of orally administered glandular kallikrein on urinary kallikrein, aldosterone and prostaglandin E (PGE) excretion, plasma renin activity (PRA), immunoreactive 6-keto PGF1 alpha and thromboxane B2 concentrations and platelet aggregation were studied in 12 patients with essential hypertension (EH)."3.67Effects of orally administered glandular kallikrein on urinary kallikrein and prostaglandin excretion, plasma immunoreactive prostanoids and platelet aggregation in essential hypertension. ( Ban, M; Ito, T; Mochizuki, M; Ogawa, K; Satake, T, 1985)
"Long-term treatment with muzolimine in patients with essential hypertension has provided very interesting results."3.67Is the antihypertensive effect of muzolimine due to volume depletion? ( Andreucci, VE; Cofelice, E; Dal Canton, A; Oliva, O; Romano, G; Russo, D; Veniero, P, 1985)
"Two patients with hypertension due to coarctation of the aorta were treated for 12 weeks with captopril at increasing doses."3.67Resistance to captopril in hypertension of coarctation of the aorta. ( Fallo, F; Mantero, F; Maragno, I, 1985)
"In order to investigate the validity of angiotensin converting enzyme inhibition with captopril as a screening test for primary aldosteronism (PA), 50 mg of captopril were administered orally to 7 patients with PA, 17 with essential hypertension (EH), 5 with renovascular hypertension (RVH), 2 with renoparenchymal hypertension (RH) and 8 normal volunteers."3.67Clinical evaluation of the captopril screening test for primary aldosteronism. ( Fujii, Y; Hamasaki, S; Inoue, J; Iwaoka, T; Miura, F; Naomi, S; Sato, T; Umeda, T, 1985)
"Mean arterial blood pressure, forearm vascular resistance, plasma norepinephrine, plasma renin activity and aldosterone responses to graded lower body negative pressure and tilt at 80 degrees were examined in 10 men with mild to moderate essential hypertension before and after 12 weeks of diltiazem (240 to 360 mg/day) therapy."3.67Effects of diltiazem on hormonal and hemodynamic responses to lower body negative pressure and tilt in patients with mild to moderate systemic hypertension. ( Beck, F; McNamara, C; Mohanty, PK; Sowers, JR; Thames, MD; Welch, B, 1985)
"Cardiovascular, baroreflex and humoral responses were evaluated in 8 patients with essential hypertension during a control period and then after oral treatment for 5 days with nicardipine hydrochloride 60 mg/d, a calcium channel antagonist."3.67Cardiovascular, baroreflex and humoral responses in hypertensive patients during nicardipine therapy. ( Biggi, A; Coruzzi, P; Musiari, L; Novarini, A; Ravanetti, C, 1985)
"The responses of plasma renin activity (PRA), plasma bradykinin (BK) and urinary kallikrein like activity (UK) associated with the infusion of angiotensin II (AII) before and after NaCl loading were investigated in pregnancy induced hypertension (PIH)."3.67[Studies on the pathophysiology of pregnancy induced hypertension--endocrinological analysis by the method of angiotensin II and NaCl loading]. ( Mochizuki, M; Morikawa, H; Yamasaki, M, 1985)
"Exchangeable sodium, blood volume, plasma norepinephrine (NE), epinephrine, renin and aldosterone levels, and pressor responses to infused NE or angiotensin II (AII) were assessed in ten patients with essential hypertension on placebo, following 6 to 8 weeks of calcium-antagonist nifedipine (NIF), 3 X 10 to 20 mg/day, and after 6 to 8 weeks on NIF combined with the diuretic chlorthalidone (CHLOR), 25 to 50 mg/day."3.67Body sodium-blood volume state, aldosterone, and cardiovascular responsiveness after calcium entry blockade with nifedipine. ( Beretta-Piccoli, C; Bianchetti, MG; Bomio, F; Luisoli, S; Marone, C; Weidmann, P, 1985)
"Radioimmunoassays of plasma hormones were carried out, and correlation coefficients between the blood somatotrophin level and blood thyrotrophic hormone, thyroxine, renin, and aldosterone, as well as between blood somatotrophin and diastolic BP, cardiac index, total peripheral resistance, the tension and ejection time, cardiac cycle duration and electrocardiographic SV1 + RV5, were calculated in 95 patients with essential hypertension and symptomatic arterial hypertensions."3.67[Concentration of somatotropic hormone in the blood in arterial hypertension of different origin]. ( Morozov, AI; Selivonenko, VG, 1985)
"Studies have been conducted to determine which, if any, of the parameters governing active Na-K transport (K and/or ouabain sensitive) are altered in vascular smooth muscle during mineralocorticoid-salt hypertension."3.67Alterations in active Na-K transport during mineralocorticoid-salt hypertension in the rat. ( Jones, AW; Magliola, L; McMahon, EG, 1986)
"Serum 18-hydroxycorticosterone, aldosterone, and potassium were measured under basal conditions in 34 patients with documented primary aldosteronism, 10 patients with essential hypertension, and 9 normal subjects."3.67The prediction of anatomical morphology of primary aldosteronism using serum 18-hydroxycorticosterone levels. ( Brown, RD; Hanson, CS; Hollifield, JW; Kem, DC; Painton, R; Tang, K; Weinberger, MH, 1985)
"Experiments were performed to characterize the hypertension produced by chronic intracerebroventricular (ICV) infusion of angiotensin II (ANG II) in conscious rats."3.67Sodium-dependent hypertension produced by chronic central angiotensin II infusion. ( Bruner, CA; Fink, GD; Weaver, JM, 1985)
"In earlier studies by our group it was shown that the urinary tetrahydroaldosterone excretion is a more reliable test for the diagnosis of primary aldosteronism than aldosterone-18-glucuronide ('urinary aldosterone')."3.6721-Deoxytetrahydroaldosterone excretion in primary hyperaldosteronism. ( Abdelhamid, S; Lewicka, S; Vecsei, P; Winter, J, 1985)
"To investigate the regulation of arterial pressure and vasoactive hormones in hypothyroidism associated with hypertension, we measured intra-arterial pressure and hourly venous hormones (renin, angiotensin II, aldosterone, catecholamines and cortisol) for 24 hours in five hypertensive patients with primary hypothyroidism before commencing treatment, and again after three to six months of thyroxine replacement therapy."3.67Hypertension in hypothyroidism: arterial pressure and hormone relationships. ( Brownlie, BE; Espiner, EA; Ikram, H; Nicholls, MG; Richards, AM; Turner, JG, 1985)
"Sixteen patients (11 M, 5 F), median age 41 years, with essential hypertension insufficiently controlled on hydrochlorothiazide 75 mg/day (DBP greater than or equal to 100 mmHg) were investigated."3.66Angiotensin II blockade during combined thiazide-beta-blocker treatment. ( Christensen, NJ; Giese, J; Ibsen, H; Leth, A; McNair, A, 1980)
"0 mg/kg prizidilol HCl, an antihypertensive with vasodilator and beta-adrenoceptor blocking actions, were given to 12 patients with primary hypertension on separate days."3.66Prizidilol, an antihypertensive with precapillary vasodilator and beta-adrenoceptor blocking actions, in primary hypertension. ( Karlberg, BE; Larsson, R; Norlander, B; Wirsén, A, 1981)
"The antihypertensive effect of captopril was tested on 19 patients with essential hypertension, WHO grade I or II."3.66[Captopril in the treatment of essential hypertension (author's transl)]. ( Braun, B; Klaus, D; Lederle, RM, 1980)
"Hemodynamic responses and behaviors of the renin-angiotensin-aldosterone system to a single administration of captopril (50 mg) were studied in 16 hypertensive patients (essential hypertension, n = 10; renovascular hypertension, n = 3; primary aldosteronism, n = 2; Cushing's syndrome, n = 1)."3.66Effects of a single administration of captopril on hemodynamics and serum angiotensin converting enzyme activity, plasma renin activity and plasma aldosterone concentration in hypertensive patients. ( Hashimoto, H; Hiwada, K; Kokubu, T, 1981)
" The plasma aldosterone responses to exogenous angiotensin II and adrenocorticotropic hormone (ACTH) were studied before and after 1 month of propranolol therapy (120-240 mg/day) in eight patients with essential hypertension."3.66Effect of propranolol therapy on aldosterone responses to angiotensin II and adrenocorticotropic hormone in essential hypertension. ( Fittingoff, DB; Golub, MS; Tuck, ML, 1981)
" Blood pressure was normal during treatment with spironolactone and during pregnancy, when the action of aldosterone and other similar steroids was presumably blocked by an increased production of progesterone; this suggests that the hypertension is dependent upon sodium-retaining steroids such as aldosterone."3.66Overproduction of sodium-retaining steroids by the zona glomerulosa is adrenocorticotropin-dependent and mediates hypertension in dexamethasone-suppressible aldosteronism. ( Bartter, FC; Gill, JR, 1981)
"Captopril was given alone and in combination with diuretics to 49 patients with hypertension for 1 to 12 mol Within 2 mo blood pressure reduction correlated with pretreatment plasma renin activity and response to the infusion of angiotensin II antagonist, but these effects were not present at 4 mo."3.66Hormonal responses to long-term converting enzyme inhibition in hypertensive patients. ( Hata, T; Kumahara, Y; Maruyama, A; Mikami, H; Naka, T; Nakamaru, M; Ogihara, T; Ohde, H, 1981)
"30% of patients with essential hypertension have a decreased adrenal response to angiotensin II (A II) on a low but not a high sodium intake."3.66Decreased adrenal responsiveness to angiotensin II: a defect present in spontaneously hypertensive rats. A possible model of human essential hypertension. ( Braley, LM; Menachery, A; Williams, GH, 1982)
"To study effects on pituitary-adrenocortical activity of a sustained block of angiotensin II formation, six 'drug-resistant' patients with essential hypertension were studied before and during treatment with an inhibitor of the angiotensin-converting enzyme (Captopril, SQ 14,225)."3.66Pituitary - adrenocortical function in patients during treatment with the angiotensin-converting enzyme inhibitor captopril. ( Angeli, A; Bisbocci, D; Lavezzaro, GC; Orlandi, F; Paccotti, P; Tabasso, R; Tamagnone, C, 1981)
"The humoral and hemodynamic effects of converting enzyme inhibition captopril are presented in two patients with primary hyperaldosteronism (PHA)."3.66Converting enzyme inhibition with captopril in patients with primary hyperaldosteronism. ( Demers, LM; Harrison, TS; Hayes, AH; Luderer, JR, 1982)
"Captopril was given to 15 unselected patients with essential hypertension (WHO II) at a dose range of 300 to 600 mg/day."3.66Angiotensin-converting enzyme inhibition, catecholamines and hemodynamics in essential hypertension. ( Agabiti-Rosei, E; Alicandri, CL; Beschi, M; Boni, E; Castellano, M; Fariello, R; Moniti, E; Muiesan, G; Muiesan, L; Romanelli, G; Zanielli, A, 1982)
"To compare the hemodynamic and humoral effects of increasing doses of captopril, blood pressure, heart rate, plasma renin activity, plasma aldosterone and angiotensin-converting enzyme activity were measured in 10 patients with mild uncomplicated essential hypertension before and after captopril given in an increasing dose of 25, 50 and 100 mg twice a day, with each dose given for 3 days."3.66Humoral and hemodynamic effects of increasing doses of captopril in patients with essential hypertension. ( Abdel-Haq, B; Magagna, A; Pedrinelli, R; Salvetti, A; Sassano, P, 1982)
"Ten milligrams nifedipine was administered orally to young and old persons with or without hypertension, and the acute effects of nifedipine on the renin-angiotensin-aldosterone system were studied one half to 3 hours later."3.66Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension. ( Hiramatsu, K; Kubota, T; Yamada, T; Yamagishi, F, 1982)
"The acute blood pressure response to the angiotensin converting enzyme inhibitor, captopril, was used to measure participation of the renin-angiotensin system in treatment-resistant hypertension."3.66Participation of the renin system in treatment-resistant hypertension as measured by acute blockade of the angiotensin converting enzyme. ( Chen, TC; Drayer, JI; Priest, RT; Weber, MA, 1982)
"Four major volume hormones may be involved in human hypertension: aldosterone, arginine vasopressin, inhibitors of NA+/K+ ATPase activity, and the natriuretic factor from specific granules of atrial cardiocytes."3.66Volume hormones and blood pressure. ( Genest, J, 1983)
"In order to clarify the influence of food on the clinical effect of angiotensin I converting enzyme inhibitor (SQ 14,225, captopril), 25 mg of the drug was administered to patients with hypertension using in a two-way crossover study design."3.66Influence of food on the clinical effect of angiotensin I converting enzyme inhibitor (SQ 14,225). ( Hatano, M; Honda, M; Izumi, Y; Kawahara, Y, 1983)
"Infusion of angiotensin II into a patient with dexamethasone-suppressible hyperaldosteronism caused a brisk increase in plasma aldosterone concentration."3.6610. Hypertension. A comparison of the effects of angiotensin II infusion and variations in salt intake on plasma aldosterone levels in normal subjects, patients with essential hypertension and patients with hyperaldosteronism. ( Brown, JJ; Fraser, R; Lever, AF; Robertson, JI; Usherwood, T; Zoccali, C, 1983)
"To investigate the role of the renin-angiotensin-aldosterone system in hypertension due to coarctation of the aorta (COA), upright mean arterial pressure (MAP), plasma renin activity (PRA) and plasma aldosterone (Aldo) were determined before and 90 minutes after a single oral dose of captopril (25 mg) in eight patients with COA and in fourteen with essential hypertension (EH)."3.66Effect of captopril on blood pressure and on the renin-angiotensin-aldosterone system in coarctation of the aorta. ( Fallo, F; Mantero, F; Maragno, I; Merola, P, 1983)
"The effects of endralazine, administered intravenously, on blood pressure, heart rate, forearm blood flow, plasma renin activity, aldosterone, adrenaline and noradrenaline were studied in five patients with essential hypertension."3.66Effects of intravenous endralazine in essential hypertension. ( Hoffmann, JJ; Thien, T; van T'Laar, A, 1983)
"The effects of penbutolol 20-30 mg twice daily and of metoprolol 50-150 mg three times daily were studied in five and nine patients, respectively, with moderate hypertension."3.66Effects of penbutolol and metoprolol on blood pressure, plasma catecholamines and renin activity in hypertensive patients. ( Dymling, JF; Hansson, BG; Hökfelt, B; Manhem, P, 1983)
"Plasma aldosterone levels were measured during two tests of inhibition in 31 hypertensive patients (13 essential hypertension, 6 bilateral adrenal hyperplasia and 12 documented Conn adenomas) on normal salt diets after withdrawal of all therapy: 1--before and after intravenous infusion of 2 I normal saline in two hours; 2--before and three hours after administration of 1 mg/kg of Captopril."3.66[A new diagnostic test for primary tumoral hyperaldosteronism]. ( Corvol, P; Dufloux, MA; Ménard, J; Plouin, PF; Sassano, P; Thibonnier, M, 1983)
"Nine patients with refractory hypertension, ranging in age from 6 to 18 years, were given captopril."3.66Effect of captopril on the renin-angiotensin system in hypertensive children. ( Chesney, RW; Friedman, AL, 1983)
"Plasma renin activity (PRA), plasma aldosterone (PA), blood uric acid (BUA), plasma concentrations of catecholamines (Pcat) and plasma volume (PV) were measured simultaneously in 24 patients with pregnancy-induced hypertension (PIH)."3.66Plasma renin activity, blood uric acid and plasma volume in pregnancy-induced hypertension. ( Boulanger, JC; Carayon, A; Coevoet, B; Comoy, E; de Fremont, JF; Demory, JE; Desailly, I; Fievet, P; Pleskov, L; Verhoest, P, 1983)
"In order to clarify the role of the kallikrein-kinin system in the hypotensive mechanisms of converting-enzyme inhibition, captopril was administered in a single oral dose of 50 mg to 17 hypertensive patients, of whom 14 had essential hypertension, one had chronic renal failure, one had primary aldosteronism, and one had glucocorticoid responsive hyperaldosteronism."3.66[Acute antihypertensive effect of captopril in hypertensive patients: with special reference to kallikrein-kinin system]. ( Fukuchi, S; Gotoh, M; Haruyama, K; Hashimoto, S; Matsui, J; Mizuno, K; Toki, T, 1983)
" The effects of 3 wk of treatment with two selective beta 1 blockers, metoprolol and atenolol, were observed in 54 patients with mild or moderate essential hypertension."3.66Predictability of antihypertensive efficacy of selective beta 1 blockers. ( Condorelli, M; Cuocolo, A; De Luca, N; Ricciardelli, B; Trimarco, B; Veniero, AM; Volpe, M, 1983)
"This study examines the influence of bromocriptine, a dopamine agonist, on circadian secretory patterns of plasma 18-hydroxycorticosterone (18-OHB) and cortisol in essential hypertension."3.66Effects of bromocriptine on the circadian rhythm of 18-hydroxycorticosterone and cortisol secretion in essential hypertensives. ( Beck, FW; Sowers, JR; Stern, N; Tuck, ML, 1983)
"To evaluate the therapeutic efficacy of oral angiotensin-converting enzyme inhibition with low-dose (average 30 mg/day) captopril in diuretic-resistant hypertension, its long-term cardiocirculatory action was determined by dye-dilution method and venous-occlusion forearm plethysmography in 11 uncontrolled patients taking a thiazide diuretic."3.66Hemodynamic and endocrine changes associated with captopril in diuretic-resistant hypertensive patients. ( Ando, K; Fujita, T; Noda, H; Sato, Y; Yamashita, K; Yamashita, N, 1982)
"The response of plasma renin activity (PRA), plasma aldosterone, 18-hydroxycorticosterone (18-OH-B), 18-hydroxydeoxycorticosterone (18-OH-DOC) and corticosterone to furosemide were compared in 20 normal control subjects, 16 patients with normal-renin essential hypertension (NREH) and 12 patients with low-renin essential hypertension (LREH)."3.66Rapid increase of mineralocorticoids after furosemide in low-renin essential hypertension: evidence for 18-hydroxycorticosterone to be a better marker than aldosterone. ( Thayil, G; Weber, PC; Witzgall, H, 1982)
"1 The long-term effects of the oral angiotensin-converting enzyme inhibitor captopril with the addition of a diuretic (chlorthalidone) were examined in 16 patients with moderate or grave hypertension."3.66Long-term captopril treatment in moderate to severe hypertension. ( Aguglia, F; Balsano, F; De Mattia, G; Ficara, C; Santucci, A, 1982)
"The role of the renin-aldosterone axis in mediating responses to antihypertensive treatment was examined in patients with essential hypertension treated with propranolol (n=50) or chlorthalidone (n=50)."3.66The role of aldosterone in the response to treatment of primary hypertension. ( Drayer, JI; Laragh, JH; Purdy, RE; Weber, MA, 1982)
"Paradoxical glucose-induced hyperkalemia (GIH) was elicited exclusively in the upright position during captopril treatment in four hypertensive patients (Group 3) without impaired glucose tolerance in three."3.66Glucose-induced hyperkalemia developing in the upright position in captopril-treated hypertensives. ( Bános, C; Csabuda, M; Gercsák, G; Molnár, Z; Pató, E; Radó, JP, 1982)
"The interrelationship between PRA, urinary aldosterone excretion, and blood pressure was studied in 11 patients with essential hypertension while receiving a diuretic (1st week) and subsequently a diuretic + oxprenolol (2nd week)."3.66The renin-angiotensin-aldosterone system and blood pressure during oxprenolol treatment in hypertensive patients pretreated with diuretics. ( Pedrinelli, R; Salvetti, A; Simonini, N, 1982)
"5 mg and 25 mg) of angiotensin I converting enzyme inhibitor (SQ 14,255, captopril) were administered to 8 patients with essential hypertension on a three-crossover study design, and the time course of mean blood pressure (MBP), plasma renin activity (PRA), plasma angiotensin converting enzyme activity (ACE-A), plasma cortisol (PC) and plasma aldosterone (PA) were determined following administration of the drug."3.66Effects of various doses of captopril on plasma aldosterone concentrations in patients with essential hypertension. ( Hatano, M; Honda, M; Izumi, Y, 1982)
"The studies were designed to explore the effect of the converting enzyme inhibitor captopril on the activity of the sympathetic nervous system during basal conditions and following graded physical exercise in patients with essential hypertension."3.66The effect of captopril on catecholamines, renin activity, angiotensin II and aldosterone in plasma during physical exercise in hypertensive patients. ( Bramnert, M; Hökfelt, B; Hulthén, UL; Manhem, P, 1981)
"Plasma concentrations and urinary excretion rate of vasopressin (VP) were examined in ten cases of severe hypertension before and during short-term treatment by Captopril (SQ 14225)."3.66Reduction of plasma and urinary vasopressin during treatment of severe hypertension by captopril. ( Aldiger, JC; Corvol, P; Menard, J; Milliez, P; Soto, ME; Thibonnier, M, 1981)
"We investigated changes in the renin-angiotensin-aldosterone system in seven patients with essential hypertension during treatment with captopril (SQ 14225) (300 to 450 mg/day) for 12 months."3.66Captopril in the long-term treatment of essential hypertension: changes in the renin-angiotensin-aldosterone system. ( Hayduk, K; Liebau, G; Riegger, GA; Steilner, H, 1982)
"Hypertension-prone, male, spontaneously hypertensive rats (SHR; n = 60) and normotensive, male, Sprague-Dawley rats (S-D; n = 60) were exposed to the relatively innocuous stimulus of heat and ether when they were 40 days of age, just before the usual onset of high blood pressure in SHR."3.66Hypersensitivity of spontaneously hypertensive rats to heat and ether before the onset of high blood pressure. ( McMurtry, JP; Wexler, BC, 1983)
"Plasma volume (PV), extracellular fluid volume (ECV) serum electrolytes, renin and aldosterone were measured before and after 1 week and 4 months of hydrochlorothiazide (HCT) treatment, 50 mg twice daily, in nine male patients with uncomplicated essential hypertension."3.66Body fluid volumes and the response of renin and aldosterone to short- and long-term thiazide therapy of essential hypertension. ( Schalekamp, MA; van Brummelen, P, 1980)
"Twenty-one patients with essential hypertension received a constant infusion of angiotensin II and des-aspartyl1-angiotensin II for 45 min on 2 consecutive days during normal sodium intake."3.66A comparative study on (des-aspartyl1)-angiotensin II and angiotensin II in patients with essential hypertension. ( Fukuchi, S; Mizuno, K; Yamazaki, M, 1980)
"Captopril was given for treatment of hypertension alone or in combination with diuretics to 32 patients for 1- to 4-mo periods."3.66Long-term effects of captopril in hypertension. ( Hata, T; Iwanaga, K; Kumahara, Y; Maruyama, A; Mikami, H; Naka, T; Nakamaru, M; Ogihara, T, 1980)
"The effect of the converting enzyme inhibitor captopril on arterial pressure, the components of the renin-angiotensin-aldosterone system, and body sodium and potassium content was studied in eight hypertensive patients with renal artery stenosis and, in conjunction with diuretics, in seven patients with hypertension unresponsive to previous treatment."3.66Captopril in clinical hypertension. Changes in components of renin-angiotensin system and in body composition in relation to fall in blood pressure with a note on measurement of angiotensin II during converting enzyme inhibition. ( Atkinson, AB; Brown, JJ; Davies, DL; Fraser, R; Kelly, P; Leckie, B; Lever, AF; Morton, JJ; Robertson, JI, 1980)
"Arterial blood pressure and plasma catecholamines, renin activity and aldosterone concentration in 12 patients with severe essential hypertension were studied before and after combined alpha- and beta- adrenoceptor blockade induced by oral labetalol treatment for 2 months."3.66Plasma catecholamines, renin and aldosterone during combined alpha- and beta- adrenoceptor blockade in patients with severe arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Pedersen, A; Pedersen, EB; Pedersen, G, 1980)
"A simultaneous analysis of the interrelationships between mean blood pressure (MBP), plasma catecholamines, plasma renin activity (PRA) and aldosterone, exchangeable body sodium, and blood volume was carried out before and after acute and chronic administration of clonidine in 15 patients with essential hypertension, in order to further elucidate the mechanism(s) of action of this drug."3.66Role of sympathetic nerve inhibition and body sodium-volume state in the antihypertensive action of clonidine in essential hypertension. ( Campese, VM; Massry, SG; Romoff, M; Telfer, N; Weidmann, P, 1980)
"A case of severe hypertension resistant to multiple drug therapy was controlled with minoxidil, captopril, and propranolol hydrochloride after treatment with these drugs alone or in other combinations had failed."3.66Interaction of minoxidil and captopril in the treatment of refractory hypertension. ( Matson, JR; Norby, LH; Robillard, JE, 1981)
"Eight patients with essential hypertension, WHO grade I-III, were studied under standardized conditions in a metabolic ward, before and after 8-20 weeks of treatment with clonidine in a maintenance dose of 300-600 micrograms/24 h."3.66Prolonged clonidine treatment: catecholamines, renin activity and aldosterone following exercise in hypertensives. ( Hökfelt, B; Manhem, P, 1981)
"The plasma aldosterone (PA) response to sodium restriction (25 mEq daily for 4 days) and to graded infusions of angiotensin II (AII, 2, 4 and 8 ng/kg/min each for 30 min) during a low-sodium intake were studied in 15 elderly subjects with mild essential hypertension versus 10 elderly normotensive subjects."3.66Plasma aldosterone response to angiotensin II in sodium-restricted elderly subjects with essential hypertension. ( Kigoshi, T; Miyamoto, M; Morimoto, S; Morise, T; Takeda, R; Takimoto, H; Uchida, K, 1981)
"The role of the renin-angiotensin system in the development of hypertension was studied by infusing an angiotensin II analog, 1-Sar, 8-Ile angiotensin II, in women with toxemia and women on estrogen-containing oral contraceptives or estrogen treatment."3.66Effects of angiotensin II analog on blood pressure, renin and aldosterone in women on oral contraceptives and toxemia. ( Kondo, K; Nagahama, S; Nakamura, R; Saruta, T; Suzuki, H, 1981)
"The effect of 5 to 9 days of metyrapone administration (400 mg/m2 every 4 h) on aldosterone, deoxycorticosterone, plasma renin activity, electrolyte balance, and blood pressure was investigated in 2 normotensive siblings (one of whom showed limited ACTH reserve), in 3 patients with hypertension and dexamethasone-suppressible hyperaldosteronism, and in a hypertensive patient with primary hyperaldosteronism due to bilateral adrenal hyperplasia."3.66Mineralocorticoid and metabolic response to metyrapone on normotensive children and children with dexamethasone-suppressible and primary hyperaldosteronism. ( Levine, LS; New, MI; Sonino, N, 1981)
" Captopril, an orally active angiotensin converting enzyme inhibitor, was abruptly withdrawn from the antihypertensive regimen of 6 patients (5 males; aged 31 to 58) with moderate to severe hypertension."3.66Captopril withdrawal after chronic therapy. ( Ferguson, RK; Green, PJ; Koffer, H; McElwain, GE; Vlasses, PH, 1981)
"The time courses of mean blood pressure (MBP), plasma renin activity (PRA), plasma aldosterone (PA), serum prostaglandin E (PGE), serum angiotensin I converting enzyme (ACE), and blood levels of angiotensin I converting enzyme inhibitor (SQ 14,225) (captopril) were studied in 6 patients with essential hypertension (5 men and 1 woman, aged 44 +/- 5."3.66Relationship between blood pressure and blood levels of angiotensin I converting enzyme inhibitor (SQ 14,225). ( Hatano, M; Honda, M; Izumi, Y; Kawahara, Y, 1981)
"Antihypertensive effect of an orally active angiotensin I-Converting enzyme inhibitor, SQ 14225 (Captopril) was assessed in 18 hypertensive patients, of whom 13 had essential hypertension, 2 had malignant hypertension, 2 had hypertension associated with chronic renal failure, and 1 had renovascular hypertension."3.66Antihypertensive effect of the oral angiotensin I-converting enzyme inhibitor in long-term treatment of hypertensive patients. ( Fukuchi, S; Gotoh, M; Matsui, J; Mizuno, K, 1981)
"Trimazosin was given for periods of at least 6 mo to 25 patients with mild to moderate essential hypertension."3.66A vasodilator that avoids renin stimulation and fluid retention: antihypertensive treatment with trimazosin. ( Aronow, WS; Brewer, DD; Drayer, JI; Lipson, JL; Ricci, BA; Weber, MA, 1982)
"The hypertensiogenic effects of 19-hydroxyandrostenedione (19-OH-A-dione) reported previously to be an amplifier of the action of aldosterone were evaluated using the same experimental procedures as for DOCA-salt hypertension in rats."3.6619-hydroxyandrostenedione as a new hypertensinogenic agent. ( Sekihara, H, 1982)
"Plasma aldosterone (PA) responses to sodium restriction (25 mEq sodium/day for 4 days) and to graded angiotensin II (AII) infusions (2, 4 and 8 ng/kg/min each for 30 min) during a low sodium intake were studied in 14 subjects with low renin essential hypertension (LREH) versus 16 normotensive subjects."3.66Aldosterone responsiveness to angiotensin II after sodium restriction in subjects with low renin essential hypertension. ( Fujimura, A; Hashiba, T; Honjo, A; Kigoshi, T; Morimoto, S; Takeda, R; Uchida, K, 1982)
"For distinguishing primary aldosteronism from essential hypertension, we use simple direct radioimmunoassays for "aldosterone" (aldosterone and other materials that react with the antibody to aldosterone) and "18-hydroxycorticosterone" (similarly) in unprocessed urine."3.66Direct radioimmunoassays for "aldosterone" and "18-hydroxycorticosterone" in unprocessed urine, and their use in screening to distinguish primary aldosteronism from hypertension. ( Abdelhamid, S; Benraad, TJ; Haack, D; Hofman, J; Lichtwald, K; Vecsei, P, 1982)
"Simultaneous measurement of the 0800-hr plasma concentrations of deoxycorticosterone (DOC), corticosterone (B), 18-hydroxycorticosterone (18-OHB), aldosterone, 18-hydroxydeoxycorticosterone (18-OHDOC) and cortisol (F) in four types of primary aldosteronism provides evidence for primary adrenal disease."3.66The mineralocorticoid hormone pathways in hypertension with hyperaldosteronism. ( Biglieri, EG; Brust, N; Chang, B; Hirai, J; Kater, CE, 1982)
"The most abundant substance in the urinary free steroid fraction of patients with primary aldosteronism has been identified as 18-hydroxycortisol."3.66Hypersecretion of a new corticosteroid, 18-hydroxycortisol in two types of adrenocortical hypertension. ( Chu, MD; Ulick, S, 1982)
"In view of recent evidence that spironolactone may inhibit synthesis of corticosteroids by a direct effect on the adrenal cortex, adrenocortical function was studied in eight patients with essential hypertension who had been treated with spironolactone from 3 months to 14 years."3.66Long term spironolactone and the adrenal cortex in essential hypertension. ( Gorchein, A; Horth, CE; James, VH; Lewis, PS; May, CN, 1980)
"Plasma concentrations of angiotensin II (AII), aldosterone, 18-hydroxycorticosterone and cortisol were measured in seven patients with benign essential hypertension and in seven age-matched control subjects before, and at frequent intervals for 2 h after the intravenous injection of frusemide (40 mg)."3.66Increased 18-hydroxycorticosterone responses to frusemide in essential hypertension. ( Fraser, R; Mason, PA; Semple, PF, 1980)
"Sequential changes in plasma renin activity and urinary aldosterone and noradrenaline were assessed in eight patients with severe hypertension after minoxidil had been added to their treatment."3.66Need for beta-blockade in hypertension reduced with long-term minoxidil. ( Brunner, HR; Ferguson, RK; Gavras, H; Jaeger, P; Jequier, E; Turini, G, 1978)
"In order to investigate the role of 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) in essential hypertension (EH), the responses of plasma 17-OH-DOC to 7 stimulation tests (furosemide test, adrenal suppression test, angiotensin II infusion test, adrenal stimulation test, metopirone test, saline infusion test and potassium chloride infusion test) and the circadian rhythm were investigated in 18 patients with essential hypertension (low renin group: 8, and normal renin group: 10)."3.66Plasma levels of 18-hydroxy-11-deoxycorticosterone in essential hypertension. ( Den, K; Hatano, M; Honda, M; Izumi, Y; Kanbegawa, A; Oguri, K; Shiratsuchi, T; Tsuchiya, M; Ueda, Y, 1978)
"To determine the mechanism underlying altered adrenal responsiveness in patients with essential hypertension, the renin-angiotensin-aldosterone axis was assessed in normotensive and hypertensive subjects using three pharmacological probes: SQ 20881, a converting enzyme inhibitor; saralasin, a competitive angiotensin antagonist with prominent agonist properties; and angiotensin itself."3.66The adrenal receptor for angiotensin II is altered in essential hypertension. ( Dluhy, RG; Hollenberg, NK; Moore, TJ; Swartz, SL; Williams, GH, 1979)
") before and during treatment with spironolactone (Sp, 75--100 mg/day) for at least 8 months was studied in 11 patients with essential hypertension."3.66Reduced response of plasma aldosterone to acute ACTH stimulation during long-term treatment with spironolactone in essential hypertension. ( Kim, KS; Miyamori, I; Miyamoto, M; Morimoto, S; Takeda, R; Uchida, K, 1979)
" In 20 subjects with uncomplicated essential hypertension, 10 of whom were on propranolol treatment, several blood samples were drawn simultaneously from the renal artery and vein after angiographic studies."3.66Noradrenaline secretion by the human kidney. ( Birkenhäger, WH; de Leeuw, PW; Falke, HE; Punt, R, 1978)
"To examine the involvement of renin-angiotensin-aldosterone system in the etiology of oral contraceptive induced hypertension, normal women (Group I), normotensive (Group II) and hypertensive (Group III) women taking Ovulen (R) were infused with a competitive angiotensin II (AII) antagonist, [1-sarcosine, 8-isoleucine] angiotensin II."3.66Effects of an angiotensin II antagonist; [sarcosine 1, isoleucine 8] angiotensin II, on blood pressure, plasma renin activity and plasma aldosterone concentration in hypertensive and normotensive subjects taking oral contraceptives. ( Hata, T; Kumahara, Y; Maruyama, A; Mikami, H; Nakamaru, M; Ogihara, T, 1979)
"We substituted minoxidil for dihydralazine in the treatment of 10 patients with refractory hypertension."3.66[Effects of minoxidil on blood pressure and plasma volume in refractory hypertension (author's transl)]. ( Alhenc-Gelas, F; Ménard, J; Morgado Vital, A; Plouin, PF, 1979)
" Blood pressure, systemic haemodynamics, plasma volume, renin and aldosterone were measured during placebo treatment and after 1, 4 and 12 weeks of hydrochlorothiazide in 13 patients with uncomplicated essential hypertension."3.66Haemodynamics during long-term thiazide treatment in essential hypertension: differences between responders and non-responders. ( Man in't Veld, A; Schalekamp, MA; Van Brummelen, P, 1979)
"The plasma aldosterone response to infused angiotensin II was determined in normal controls and in patients with normal renin and with low renin essential hypertension."3.66Enhanced adrenal responsiveness to angiotensin II in patients with low renin essential hypertension. ( Adlin, VE; Channick, BJ; Kanefsky, TM; Marks, AD; Marks, DB, 1979)
"To determine if the abnormally large increases in levels of plasma aldosterone which occur during infusion of angiotensin II in some patients with essential hypertension are due to abnormal decreases in the metabolic clearance of aldosterone, we measured clearances of aldosterone before and during infusion of angiotensin II in 12 patients with essential hypertension and in 10 normal subjects."3.66The metabolic clearance of aldosterone decreases similarly during infusion of angiotensin II in patients with essential hypertension and in normal subjects. ( Brown, RD; Wisgerhof, M, 1979)
"In essential hypertension mean basal (supine) and stimulated plasma renin activity (2 h upright posture + 40 mg furosemide intraveneously) decreased progressively with age."3.66Age- and sex-related differences in plasma aldosterone in essential hypertension. Relationship to plasma renin activity. ( Alasso, I; Glänzer, K; Vetter, H; Vetter, W, 1979)
"Plasma concentrations of angiotensin II (AII) were studied in 36 patients with primary (essential) hypertension and 15 normotensive control subjects during basal (1 h supine rest), upright and frusemide-stimulated (80 mg orally) conditions."3.66Angiotensin II in primary hypertension, relationship to plasma renin activity, aldosterone and urinary electrolytes. ( Karlberg, BE; Tolagen, K, 1979)
"Adrenal responsiveness to angiotensin II (AII) and the diastolic blood pressure responses to saralasin were studied in 19 patients with high renin essential hypertension (HREH) on a 10-meq Na(+)/100 meq K(+) diet."3.66Abnormal adrenal responsiveness and angiotensin II dependency in high renin essential hypertension. ( Bavli, SZ; Dluhy, RG; Hollenberg, NK; Leung, FK; Moore, TJ; Solomon, HS; Williams, GH, 1979)
"3%) the normal, aldosterone-18-glucuronide concentration was clinically misleading, but increased free aldosterone and/or tetrahydroaldosterone values suggested the presence of hyperaldosteronism, which in many of these cases was confirmed by elevated excretion of the possible major aldosterone precursor 18-hydroxycorticosterone (18-OH-B)."3.66Dissociation in the excretion of different aldosterone metabolites and unmetabolized ('free') aldosterone in hypertension. ( Abdelhamid, S; Fiegel, P; Gless, KH; Haack, D; Lichtwald, K; Vecsei, P; Walb, D, 1979)
" To characterize the renin-angiotensin-aldosterone system in elderly hypertensive patients, an angiotensin II antagonist, [Sar1,Ile8]angiotensin II, was infused into individuals 60 years old and older with and without hypertension."3.66Studies on the renin-angiotensin-aldosterone system in elderly hypertensive patients with an angiotensin II antagonist. ( Hata, T; Kumahara, Y; Mandai, T; Maruyama, A; Mikami, H; Nakamaru, M; Ogihara, T, 1979)
"Arterial blood pressure and plasma catecholamines, renin activity and aldosterone concentration in 12 patients with severe essential hypertension were studied before and after combined alpha- and beta-adrenergic receptor blockage induced by oral labetalol treatment for 2 months."3.66Effect of oral labetalol on plasma catecholamines, renin and aldosterone in patients with severe arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Pedersen, A; Pedersen, EB; Pedersen, G, 1979)
"Succinamyl-arg-val-tyr-val-his-pro-phenylglycine acetate (succinamyl1-val5-phenylglycine acetate3-A II), an analogue of angiotensin II, has a pressor effect upon patients suffering from primary and secondary hypertension regardless of prevailing plasma renin concentration."3.66Effect of an angiotensin II analogue upon blood pressure, plasma renin concentration and plasma aldosterone in hypertensive patients. ( Vierhapper, H; Waldhäusl, W, 1979)
"The effect of furosemide on urinary kallikrein excretion was studied in 10 patients with essential hypertension and 9 normal volunteer subjects."3.66Effect of furosemide on urinary kallikrein excretion in patients with essential hypertension. ( Abe, K; Chiba, S; Irokawa, N; Ito, T; Kusaka, T; Miyazaki, S; Ritz, K; Saito, K; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K, 1978)
"Seventy-nine patients with essential hypertension were evaluated for peripheral renin activity in response to injection of 60 mg of furosemide and to upright posture."3.66The multiple factors affecting plasma renin activity in essential hypertension. ( Corder, CN; McDonald, RH; Shuman, J; Vagnucci, AH, 1978)
"Studies were undertaken to determine if the dissociation of aldosterone and plasma renin activity in low-renin essential hypertension is due to altered adrenal responsiveness to angiotensin II."3.66Increased adrenal sensitivity to angiotensin II in low-renin essential hypertension. ( Brown, RD; Wisgerhof, M, 1978)
"To determine the influence of dietary sodium intake on the effects of hydrochlorothiazide (HCT) on blood pressure (BP), serum electrolytes, renin and aldosterone, nine male patients with uncomplicated essential hypertension were studied during the following therapeutic regimes: 1) sodium restriction alone (50 mmol/day), 2) sodium restriction combined with HCT (50 MG TWICE DAILY), 3) HCT alone, and 4) sodium restriction combined with HCT."3.66Influence of sodium intake on hydrochlorothiazide-induced changes in blood pressure, serum electrolytes, renin and aldosterone in essential hypertension. ( de Graeff, J; Schalekamp, M; van Brummelen, P, 1978)
" in 1975 revealed that the antihypertensive and natriuretic effects of furosemide were markedly blunted or abrogated by indomethacin in both normotensive and hypertensive man, it has been postulated that the ameliorative effects of furosemide in human essential hypertension might be mediated by release of intrarenal prostaglandins."3.66Antihypertensive effect of volume depletion: interrelation with renal prostaglandins. ( Attallah, A; Braselton, WE; Düsing, R; Lee, JB, 1978)
"Eleven patients with hypertension secondary to renal disease were treated with hydrochlorothiazide or furosemide plus other drugs to normalize blood pressure."3.66Use of diuretics in treatment of hypertension secondary to renal disease. ( Bank, N; Lief, PD; Piczon, O, 1978)
"In order to evaluate the relationship between aldosterone status and the blood pressure-lowering effect of spironolactone, 38 patients with essential hypertension were treated with spironolactone (400 mg/day) during one week in hospital on a rigidly sodium-restricted diet."3.66Role of aldosterone in the antihypertensive effect of spironolactone in essential hypertension. ( Benraad, H; Benraad, T; Drayer, J; Hoefnagels, W; Kloppenborg, P, 1978)
"In 34 patients saralasin was infused after variable degrees of sodium depletion in order to differentiate between essential and renin-induced hypertension."3.66[Saralasin-induced changes of blood pressure, renin and aldosterone in essential and renal hypertension (author's transl)]. ( Beyer, J; Hayduk, K; Liebau, G; Steiner, B, 1978)
"Minoxidil-induced sequential changes in plasma renin activity, urinary aldosterone and norepinephrine excretion were assessed in 11 patients with severe hypertension receiving propranolol or oxprenolol, chlorthalidone and spironolactone."3.66[Long-term minoxidil therapy: renin, aldosterone, noradrenaline and the need for beta blockers]. ( Brunner, HR; Ferguson, RK; Gavras, H; Jaeger, P; Jéquier, E; Turini, GA, 1978)
"The blood pressure response to the angiotensin II analog 1-sar-8-ala-angiotensin II, or saralasin, was studied in five patients with clinical and laboratory evidence of Cushing's syndrome."3.66Evidence for an angiotensinogenic mechanism of the hypertension of Cushing's syndrome. ( Anderson, GH; Dalakos, TG; Elias, AN; Schroeder, ET; Streeten, DH, 1978)
"The effect of indomethacin on plasma renin activity (PRA), urinary aldosterone, 17 OH ketogenic steroids and plasma cortisol was studied in twenty-three patients with essential hypertension and compared in eleven patients to oxprenolol effect by 2 x 2 factorial trial."3.66The effect of indomethacin on plasma renin activity and urinary aldosterone of patients with essential hypertension. ( Arzilli, F; Cavasinni, L; Pedrinelli, R; Poli, L; Salvetti, A; Sassano, P, 1978)
"A previously unidentified mineralocorticoid, 16beta-hydroxydehydroepiandrosterone (16beta OH-DHEA) has recently been isolated from urine extracts of patients with low-renin hypertension and reported to possess one-fortieth the mineralocorticoid potency of aldosterone by bioassay."3.65Interaction of 16beta-hydroxydehydroepiandrosterone with renal mineralocorticoid receptors. ( Gomez-Sanchez, C; Higgins, JR; Holland, OB; Kaplan, NM; Kem, DC; Wambach, G, 1977)
"Adrenal and vascular responsiveness to graded doses of angiotensin II (A II) were recorded for seven normal subjects and 12 patients with essential hypertension while in balance on an intake of 200 mEq sodium/100 mEq potassium."3.65Enhanced aldosterone response to angiotensin II in human hypertension. ( Dluhy, RG; Kisch, ES; Williams, GH, 1976)
"Plasma concentrations of progesterone (P), deoxycorticosterone (DOC), 17-hydroxyprogesterone (17-OH P), corticosterone (B), deoxycortisol (S), cortisol (F), and aldosterone were measured in 8 control subjects and in 10 patients with low and normal renin essential hypertension (EH) before and 4 and 8 h after an iv infusion of 25 units of ACTH."3.65Response of several adrenal steroids to ACTH stimulation in essential hypertension. ( Genest, J; Guthrie, GP; Honda, M; Kuchel, O; Messerli, FH; Nowaczynski, W; Tolis, G, 1977)
"The blood pressure response to propranolol treatment was analyzed retrospectively in 187 patients with benign essential hypertension."3.65Unexpected pressor responses to propranolol in essential hypertension. An interaction between renin, aldosterone and sympathetic activity. ( Case, DB; Drayer, JI; Keim, HJ; Laragh, JH; Weber, MA, 1976)
"To understand the role of the renin-angiotensin-aldosterone system in the pathogenesis of human hypertension, in serial studies we have blocked the system using three different pharmacologic probes: 1) reduction of renin secretion by administration of the beta receptor blocker, propranolol; 2) blockade of the action of angiotensin II by infusion of saralasin, a competitive antagonist of angiotensin II; and 3) blockade of the enzymatic conversion of angiotensin I to angiotensin II by infusing a nonapeptide competitive inhibitor."3.65Blockade of renin or angiotensin for understanding human hypertension: a comparison of propranolol, saralasin and converting enzyme blockade. ( Case, DB; Keim, H; Laragh, JH; Wallace, JM, 1977)
"In various kinds of hypertension clonidine induced a decrease in urinary catecholamines, plasma renin activity and urinary aldosterone, concommitant with a fall in blood pressure and pulse rate in both short term and chronic studies."3.65The effect of clonidine and penbutolol, respectively on catecholamines in blood and urine, plasma renin activity and urinary aldosterone in hypertensive patients. ( Hansson, BG; Hedeland, H; Hökfelt, B, 1975)
"To investigate the interaction between the renin angiotensin aldosterone system and the renal prostaglandin (PG), urinary excretion of PGE, urinary excretion of main urinary metabolite (MUM) of PGF2a, urinary excretion of aldosterone, and plasma renin activity were measured before and after infusion of 1-Sar-8-Ile-Angiotensin II, a specific competitive inhibitor of angiotensin II, in 18 patients with essential hypertension under normal and low sodium diets."3.65Effects of 1-Sar-8-Ile-angiotensin II on urinary prostaglandin excretion in patients with essential hypertension. ( Abe, K; Chiba, S; Irokawa, N; Ito, T; Otsuka, Y; Ritsu, K; Saito, K; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K, 1977)
"In 79 patients with essential hypertension, treatment with propranolol hydrochloride and chlorthalidone together produced significantly greater falls in both systolic and diastolic blood pressures than were obtained with either drug alone."3.65Renin reactivity as a determinant of responsiveness to antihypertensive treatment. ( Case, DB; Drayer, JI; Laragh, JH; Lopez-Ovejero, JA; Weber, MA, 1977)
"This study was undertaken to evaluate the effect of chronic diuretic therapy with chlorothiazide on the course of salt hypertension in hypertension-resistant (R) and hypertension-sensitive (S) strains of rats."3.65Influence of thiazide on salt hypertension. ( Dahl, LK; Iwai, J; Ohanian, EV, 1977)
"Chronic hypertension has been produced in mongrel dogs by the long-term oral administration of metyrapone (100 mg/kg per day)."3.65Multifactorial analysis of chronic hypertension induced by electrolyte-active steroids in trained, unanesthetized dogs. ( Bravo, EL; Dustan, HP; Tarazi, RC, 1977)
"Adrenal responsiveness to angiotensin II was evaluated in patients with "normal-renin" hypertension."3.65Aldosterone regulation in essential hypertension: altered adrenal responsiveness to angiotensin II. ( Dluhy, RG; Moore, TJ; Williams, GH, 1977)
"In 50 patients with essential hypertension treated with chlorthalidone, 100 mg daily for 6 weeks, treatment responders (fall in mean pressure, greater than or equal to 10%) and nonresponders experienced similar weight and electrolyte changes."3.65Disparate patterns of aldosterone response during diuretic treatment of hypertension. ( Drayer, JI; Laragh, JH; Rev, A; Weber, MA, 1977)
"To investigate the role of the renin angiotensin system in the pathogenesis of hypertension in Cushing's syndrome two patients with hypercorticism were infused with 20 mg saralasin (1-sar-8-ala-angiotensin II) over a period of 30 minutes under constant blood pressue control."3.65The effect of saralasin (1sar-8-ala-angiotensin II) on blood pressure in patients with Cushing's syndrome. ( Beckerhoff, R; Cottier, P; Redlich, B; Siegenthaler, W; Vetter, H; Vetter, W, 1976)
"To investigate the roles of angiotensin II and sodium in essential high-renin, normal-renin and low-renin hypertension, 14 patients received the competitive antagonist of angiotensin II, saralasin, during periods of sodium depletion and repletion."3.65Reciprocal relation between renin dependency and sodium dependency in essential hypertension. ( Brunner, HR; Gavras, H; Gavras, I; Ribeiro, AB, 1976)
"Plasma aldosterone concentration (PAC), plasma renin concentration (PRC), plasma potassium, plasma sodium and blood pressure (BP) have been measured in 22 patients with essential hypertension before and after treatment for one month with alprenolol."3.65Relationship between plasma aldosterone concentration and plasma potassium in patients with essential hypertension during alprenolol treatment. ( Kornerup, HJ; Pedersen, EB, 1976)
"Compared with a group of normal pregnant women, matched for age, parity, posture, and length of gestation, women with hypertension and proteinuria in the last trimester had significantly lower plasma concentrations of renin, renin substrate and angiotensin II."3.65Studies of the renin-angiotension-aldosterone system, cortisol, DOC, and ADH in normal and hypertensive pregnancy. ( Doig, A; Fraser, R; Morton, JJ; Parboosingh, J; Robertson, JI; Weir, RJ; Wilson, A, 1976)
"The effect of saralasin in lowering blood pressure and plasma aldosterone concentration in normal subjects, both sodium-replete and sodium-deplete, and in patients with various forms of hypertension, is closely related to the basal plasma angiotensin II concentration."3.65The effects of the angiotensin II antagonist saralasin on blood pressure and plasma aldosterone in man in relation to the prevailing plasma angiotensin II concentration. ( Brown, JJ; Brown, WC; Fraser, R; Lever, AF; Morton, JJ; Robertson, JI; Rosei, EA; Trust, PM, 1976)
"The responses of blood pressure, plasma renin activity (PRA) and plasma aldosterone concentration (PAC) to infusion of either angiotensin II (10 ng/Kg/min) or norepinephrine (100 ng/Kg/min) were observed in 25 patients with essential hypertension."3.65Effect of pressor agents on blood pressure, plasma renin activity and plasma aldosterone concentration in essential hypertension. ( Yamamoto, Y, 1975)
"Plasma aldosterone, plasma renin activity, sodium and potassium in the plasma and the urine were determinated under acute stimulation with saline-depletion (furosemide) and under acute suppression with saline infusion in 40 patients with primary hypertension stage I, 19 patients with primary hypertension stages II and III, and 11 patients with renal hypertension (chronic glomerulonephritis and chronic pyelonephritis)."3.65[Plasma aldosterone and plasma renin activity in patients with essential and renal hypertension under acute stimulation with saline depletion and acute suppression with saline infusion]. ( Klaus, D; Klumpp, F; Lemke, R; Zehner, J; Zöfel, P, 1975)
"The anti-hypertensive effect of spironolactone and thiabutazide was tested on 47 unselected patients with primary hypertension."3.65[Spironolactone and thiabutazide in the treatment of essential hypertension (author's transl)]. ( Braun, B; Klaus, D; Klump, F; Lemke, R; Zehner, J; Zöfel, P, 1975)
"The response of plasma aldosterone to fludrocortisone administration (400 mug 12-hourly for 3 days) was studied in twenty-two patients with primary hyperaldosteronism."3.65Response of plasma aldosterone to fludrocortisone in primary hyperaldosteronism and other forms of hypertension. ( Allison, ME; Brown, JJ; Ferriss, JB; Fraser, R; Lever, AF; Luke, RG; Padfield, PL; Robertson, JI, 1975)
"The effects of the antihypertensive imidazoline compounds 2-(5 fluor-0-toluidine)-2-imidazoline hydrochloride (ST 600) and 2-(2, 6 dichlorophenylamine)-2-imidazoline hydrochloride (ST 155, clonidine, Catapres) on intra-arterial pressure, cardiac output, stroke volume, heart rate, total peripheral resistance, renal blood flow, glomerular filtration rate, renal vascular resistance, plasma volume, plasma renin and aldosterone concentration were studied in five patients with essential hypertension."3.65Comparison between the effects of ST 600 and clonidine. ( Birkenhäger, WH; Kho, TL; Schalekamp, MA; Wester, A; Zaal, GA, 1975)
"Acebutolol, a new cardioselective beta-blocking agent, has been given for 5 days, at a daily dosage of 600 mg to 8 patients with mild essential hypertension."3.65[Effects of acebutolol on the renin-aldosterone system in essential arterial hypertension]. ( Corvol, P; Ménard, J; Plouin, PF, 1975)
" have applied the diazoxide test for the screening of primary hiperaldosteronism to 22 nephropatic patients suffering from hypertension and with different degrees of renal function."3.65[Diazoxide test in the diagnosis of arterial hypertension: modifications in the levels of renin and aldosterone in blood of patients with various restrains of the renal function]. ( Albertini, A; Cecchettin, M; Ghielmi, S; Maiorca, R; Orlandini, A; Signorini, C, 1975)
"In 19 control subjects, 33 patients with essential hypertension and normal plasma renin activity (PRA) and 11 patients with low PRA, secretory rates of 18-hydroxy-11-deoxy-corticosterone (18-OH DOC), 11-deoxycorticosterone (DOC) and corticosterone were measured."3.65Mineralocorticoid secretion in essential hypertension with normal and low plasma renin activity. ( Boucher, R; Genest, J; Honda, M; Kubo, S; Kuchel, O; Messerli, FH; Nowaczynski, W; Seth, K; Tolis, G, 1976)
"Plasma renin activity, arterial and venous angiotensin II (A II), plasma aldosterone, and sodium excretion were measured in a group of 101 patients with mild essential hypertension."3.65Relation between plasma renin activity, angiotensin, and aldosterone and blood pressure in mild untreated hypertension. ( Horvath, JS; Moore, MA; Russell, RP; Walker, WG; Whelton, P, 1976)
"The effect of triamterene, a potassium-retaining natriuretic and diuretic agent, on arterial blood pressure was studied in 31 patients with essential hypertension; there were seven patients with low plasma renin activity and 24 patients with normal plasma renin activity."3.65Triamterene-induced changes in aldosterone and renin values in essential hypertension. Evidence of a role for aldosterone in preventing blood pressure reduction. ( Drayer, JI; Keim, HJ; Laragh, JH; Thurston, H, 1976)
"A 44-year old woman without history of hypertension in her 4 pregnancies was hospitalized for hemoptysia and found to have hypertension 230/120 to 250/150: she had been taking 2 tablets of Lyndiol (5 mg lynestrenol and ."3.65[A case of arterial hypertension imputable to an estroprogestational contraceptive. Implication of the renin-angiotensin-aldosterone system]. ( Béquart, P; Boulangé, M; Camelot, G; Fontenaille, C, 1969)
"The effect of prolonged preoperative treatment with spironolactone has been studied in a series of 67 patients with hypertension, aldosterone excess, and low plasma renin."3.65Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin. ( Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Haywood, E; Lever, AF; Robertson, JI, 1972)
"The content of aldosterone, corticosterone, and cortisol has been assayed in normal adrenal tissue obtained at autopsy and in adrenal adenomas from both normotensive and hypertensive patients obtained at autopsy and from patients with primary aldosteronism obtained at surgery."3.64The steroid content of adrenal adenomas and measurements of aldosterone production in patients with essential hypertension and primary aldosteronism. ( Kaplan, NM, 1967)
"Patients with treatment-resistant hypertension who received baxdrostat had dose-related reductions in blood pressure."3.30Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension. ( Alp, N; Bhatt, DL; Brown, MJ; Freeman, MW; Halvorsen, YD; Isaacsohn, J; Marshall, W; Murphy, B; Pater, M; Pearce, C; Srivastava, A, 2023)
"High aldosterone is a key driver of hypertension and long-term negative sequelae."3.30CYP11B2 inhibitor dexfadrostat phosphate suppresses the aldosterone-to-renin ratio, an indicator of sodium retention, in healthy volunteers. ( Brooks, A; Brunner, HR; Groessl, M; Hossack, S; Mulatero, P; Schumacher, C; Steele, RE; Vogt, B, 2023)
" Salt restriction, cortisol after dexamethasone suppression test and dosage of renin-angiotensin-aldosterone-system (RAAS) blockers were independently associated with BP reduction."3.30Moderate dietary salt restriction improves blood pressure and mental well-being in patients with primary aldosteronism: The salt CONNtrol trial. ( Adolf, C; Bidlingmaier, M; Britz, V; Heinrich, DA; Kunz, S; Künzel, H; Lechner, A; Müller, LM; Nowotny, HF; Potzel, AL; Reincke, M; Sarkis, AL; Schneider, H; Seiter, TM; Sturm, L, 2023)
"Obstructive sleep apnea is a chronic, sleep-related breathing disorder, which is an independent risk factor for cardiovascular disease."3.01Influence and implications of the renin-angiotensin-aldosterone system in obstructive sleep apnea: An updated systematic review and meta-analysis. ( Chai, CS; Goh, SL; Lim, LL; Lim, QH; Loh, HH; Sukor, N; Yee, A, 2023)
"Primary aldosteronism (PA) is a highly prevalent yet underdiagnosed secondary cause of hypertension."3.01Personalized Treatment of Patients With Primary Aldosteronism. ( Chen Cardenas, SM; Khairi, S; Obeid, H; Turcu, AF, 2023)
"Hypertension is the definitive risk factor for cardiovascular disease."3.01CASZ1: a promising factor modulating aldosterone biosynthesis and mineralocorticoid receptor activity. ( Itoh, H; Kurihara, I; Shibata, H; Sone, M; Yokota, K, 2023)
"The diagnosis and treatment of primary aldosteronism is of paramount significance, since depending on its subtype, surgical or pharmaceutical intervention can lead to the full recovery of the patient."3.01[The genetic background of primary aldosteronism]. ( Igaz, P; Vékony, B, 2023)
"Primary aldosteronism (PA) is the leading cause of curable endocrine hypertension, which is associated with a higher risk of cardiovascular and metabolic insults compared to essential hypertension."3.01Cardiovascular and metabolic characters of ( Chang, CC; Chang, YY; Chen, ZW; Chou, CH; Hung, CS; Lee, BC; Liao, CW; Lin, YH; Lu, CC; Pan, CT; Peng, KY; Tsai, CH; Wu, VC, 2023)
"Emerging antenatal risk factors such as preeclampsia appear to increase the risk of hypertension and cardiovascular disease across the life course in both the offspring and women after pregnancy."3.01Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American ( Alexander, BT; August, P; Bertagnolli, M; Ferranti, EP; Grobe, JL; Jones, EJ; Loria, AS; Safdar, B; Sequeira-Lopez, MLS; South, AM, 2023)
"Both factors apply to primary aldosteronism, which is woefully underdiagnosed as a cause of hypertension and end-organ damage."3.01Underdiagnosis of Primary Aldosteronism: A Review of Screening and Detection. ( Bhalla, V; Funes Hernandez, M, 2023)
"Primary aldosteronism is associated with an increased risk of cardiovascular disease and kidney dysfunction compared to essential hypertension."3.01The Effect of Aldosterone on Cardiorenal and Metabolic Systems. ( Abe, M; Kobayashi, H; Otsuka, H, 2023)
"Primary aldosteronism (PA) is characterized by dysregulated, renin-independent aldosterone excess."3.01Primary Aldosteronism Prevalence - An Unfolding Story. ( Charoensri, S; Turcu, AF, 2023)
"Primary aldosteronism (PA), once considered a rare disease, is being increasingly recognized as an important cause of hypertension."3.01Improving Detection Rates for Primary Aldosteronism. ( Fuller, PJ; Libianto, R; Russell, G; Stowasser, M; Yang, J, 2023)
"Aldosterone measurements have been changed to the CLEIA method."3.01Recent progress in the diagnosis and treatment of primary aldosteronism. ( Shibata, H; Yoshida, Y, 2023)
"Aldosterone is a steroid hormone produced in the zona glomerulosa (ZG) of the adrenal cortex."3.01Ca ( Dinh, HA; Scholl, UI; Stölting, G, 2023)
"Primary aldosteronism (PA) is the most common cause of secondary hypertension."3.01Advances in the molecular imaging of primary aldosteronism. ( Cheng, G; Ren, X; Wang, Z, 2023)
"Primary aldosteronism, or Conn syndrome, is the most common endocrine cause of hypertension."3.01Mineralocorticoid receptor signalling in primary aldosteronism. ( Cole, TJ; Fuller, PJ; Yang, J; Young, MJ, 2023)
"Primary aldosteronism (PA) is a leading global cause of secondary hypertension."3.01Key to the Treatment of Primary Aldosteronism in Secondary Hypertension: Subtype Diagnosis. ( Liu, S; Pang, H; Xu, L; Zuo, R, 2023)
"Primary aldosteronism (PA), characterized by inappropriately high concentrations of the adrenal-derived hormone aldosterone, is the most common endocrine cause of arterial hypertension."3.01Primary aldosteronism 2.0: an update for clinicians on diagnosis and treatment. ( Kocjan, T; Pilz, S; Theiler-Schwetz, V; Trummer, C, 2023)
" The former dosage of ACEis/ARBs was continued in one group while in another group, the ACEis/ARBs were replaced by amlodipine ± carvedilol according to the dose equivalents."3.01Effects of Renin-Angiotensin-Aldosterone Inhibitors on Early Outcomes of Hypertensive COVID-19 Patients: A Randomized Triple-Blind Clinical Trial. ( Ashraf, H; Bahreini, M; Ghoghaei, M; Najmeddin, F; Rasooli, F; Salehi, M; Soleimani, A; Solhjoo, M, 2021)
"Aldosterone was not associated with IMMR, insulin sensitivity, or blood pressure and was unaffected by weight loss."2.87Aldosterone Is Not Associated With Metabolic and Microvascular Insulin Sensitivity in Abdominally Obese Men. ( de Leeuw, PW; Houben, AJHM; Joris, PJ; Kusters, YHAM; Mensink, RP; Plat, J; Schalkwijk, CG; Scheijen, JLJM; Schütten, MTJ; Stehouwer, CDA; van de Waarenburg, MPH, 2018)
"Hypertension is prevalent in chronic kidney disease (CKD)."2.87Non-uniform relationship between salt status and aldosterone activity in patients with chronic kidney disease. ( Andrew, R; Freel, EM; Homer, NZM; Jardine, AG; Mark, PB; McQuarrie, EP; Rankin, AJ; Taylor, AHM, 2018)
"Subjects with hypertension are frequently obese or insulin resistant, both conditions in which hyperuricemia is common."2.84Dietary Sodium Modifies Serum Uric Acid Concentrations in Humans. ( Johnson, RJ; Kelly, J; MacGinley, RJ; Major, TJ; Merriman, TR; Todd, AS; Walker, RJ, 2017)
"Aldosterone excretion was determined by 24 h urine (24h-UAldo) collected at randomization and after 6 months of follow-up."2.84Effects of continuous positive airway pressure treatment on aldosterone excretion in patients with obstructive sleep apnoea and resistant hypertension: a randomized controlled trial. ( Cavalcanti, AH; Cortez, AF; de Souza, F; Margallo, V; Muxfeldt, ES; Salles, GF, 2017)
"Primary aldosteronism (PA) is the primary cause of secondary hypertension."2.82Adrenal venous sampling in the diagnostic workup of primary aldosteronism. ( Betz, MJ; Zech, CJ, 2022)
"After confirmation of Conn's syndrome a differentiation between a unilateral and bilateral adrenal disease is necessary for further treatment planning."2.82[Conn's syndrome-Frequent and still too rarely diagnosed to underdiagnosed]. ( Adolf, C; Fuss, CT; Hahner, S; Heinrich, DA, 2022)
"Primary aldosteronism (PA) is an endocrine related condition leading to arterial hypertension due to inappropriately high and unregulated aldosterone concentration."2.82Primary Aldosteronism, Aldosterone, and Extracellular Vesicles. ( Carvajal, CA; Fardella, CE; Pérez, JA; Tapia-Castillo, A, 2022)
"Primary aldosteronism (PA) is the most common cause of secondary arterial hypertension."2.82[Diagnosis of primary hyperaldosteronism]. ( Araujo-Castro, M; Parra-Ramírez, P, 2022)
"Primary aldosteronism, the most common secondary form of hypertension, is thought to be present in ≈5% to 10% of hypertensive adults."2.82Primary Aldosteronism: Where Are We Now? Where to From Here? ( Carey, RM; Funder, JW, 2022)
"Primary aldosteronism (PA) affects millions of individuals worldwide."2.82High Prevalence of Autonomous Aldosterone Production in Hypertension: How to Identify and Treat It. ( Lieberman, L; Turcu, AF; Wannachalee, T, 2022)
"Superimposed preeclampsia complicates about 20% of pregnancies in women with chronic hypertension and is associated with increased maternal and perinatal morbidity compared with preeclampsia alone."2.82Chronic hypertension and superimposed preeclampsia: screening and diagnosis. ( Kametas, NA; Nicolaides, KH; Nzelu, D, 2022)
"Salt and inflammation are placed in the middle of the mosaic because both factors influence each of the remaining pieces."2.82Mosaic theory revised: inflammation and salt play central roles in arterial hypertension. ( Benitah, JP; Hengel, FE; Wenzel, UO, 2022)
"Aldosterone levels were low or in the reference range in 98% of the cases when available."2.8211-Deoxycorticosterone Producing Adrenal Hyperplasia as a Very Unusual Cause of Endocrine Hypertension: Case Report and Systematic Review of the Literature. ( Asla, Q; Aulinas, A; Hanzu, FA; Lerma, E; Pérez, JI; Rodrigo, MT; Sardà, H; Urgell, E; Webb, SM, 2022)
"Primary aldosteronism (PA) is a pathological condition characterized by an excessive aldosterone secretion; once thought to be rare, PA is now recognized as the most common cause of secondary hypertension."2.82Primary Aldosteronism and Resistant Hypertension: A Pathophysiological Insight. ( Arata, S; Bioletto, F; Bollati, M; Ghigo, E; Lopez, C; Maccario, M; Parasiliti-Caprino, M; Ponzetto, F; Procopio, M, 2022)
"Primary aldosteronism (PA) is the most common and potentially curable form of secondary hypertension, affecting 5-10% of primary care patients with hypertension."2.82Performance of the aldosterone-to-renin ratio as a screening test for primary aldosteronism in primary care. ( Ariens, J; Choy, KW; Horvath, AR; Yang, J, 2022)
"Primary aldosteronism (PA) in pregnancy (PAP) can be a serious condition and is challenging to diagnose."2.82Management and Outcomes of Primary Aldosteronism in Pregnancy: A Systematic Review. ( Rossi, GP; Rossitto, G; Sanga, V; Seccia, TM, 2022)
"Primary aldosteronism (PA) is the most common form of secondary arterial hypertension, with a prevalence of approximately 20% in patients with resistant hypertension."2.82Pathogenesis of Primary Aldosteronism: Impact on Clinical Outcome. ( Almeida, MQ; Guimaraes, AG; Santana, LS, 2022)
"Primary aldosteronism (PA) is the leading cause of secondary hypertension, accounting for over 10% of patients with high blood pressure."2.82Update on the Genetics of Primary Aldosteronism and Aldosterone-Producing Adenomas. ( Faucz, FR; Hannah-Shmouni, F; Pitsava, G; Stratakis, CA, 2022)
"Primary aldosteronism is a common cause of hypertension and is a risk factor for cardiovascular and renal morbidity and mortality, via mechanisms mediated by both hypertension and direct insults to target organs."2.82Primary aldosteronism - a multidimensional syndrome. ( Turcu, AF; Vaidya, A; Yang, J, 2022)
" Orthostatic hypotension is a concern with the use of α1-blockers especially in the elderly, and requires careful initial bedtime dosing and avoiding overdosing."2.82Role of α1-blockers in the current management of hypertension. ( Buranakitjaroen, P; Cheng, HM; Chia, YC; Kario, K; Li, H; Li, Y; Sogunuru, GP; Tay, JC; Van Huynh, M; Wang, JG; Wang, TD; Xu, TY, 2022)
"Arterial hypertension is a major risk factor for cardiovascular disease."2.82Who should be screened for primary aldosteronism? A comprehensive review of current evidence. ( Chen, CH; Cheng, HM; Chia, YC; Huang, WC; Kario, K; Lin, YH; Siddique, S; Sogunuru, G; Tay, JC; Wu, VC, 2022)
"Both primary aldosteronism and obstructive sleep apnea are well-known causes of hypertension and contribute to increased cardiovascular morbidity and mortality independently."2.82Primary aldosteronism and obstructive sleep apnea: What do we know thus far? ( Loh, HH; Sukor, N, 2022)
"Primary aldosteronism is the most common form of secondary arterial hypertension, due to excessive aldosterone production from the adrenal gland."2.82Vascular and hormonal interactions in the adrenal gland. ( Abdellatif, AB; Boulkroun, S; Fernandes-Rosa, FL; Zennaro, MC, 2022)
"Hypertension is a major public health problem, affecting more than a quarter of the world's population causing serious cardiovascular problems."2.82New Genetic Polymorphisms as an Epidemiological Factor of Arterial Hypertension in Patients with Hyposodical Diet. ( Aguilar Aldrete, ME; Cabrera-Pivaral, CE; Flores-Alvarado, LJ; López-Toledo, S; Parada-Luna, F; Ramírez-García, SA; Ruiz, DM, 2022)
"Increased abdominal obesity is associated with increased cardiovascular risk, especially in African American women."2.82Relationship Between Obesity, Hypertension, and Aldosterone Production in Postmenopausal African American Women: A Pilot Study. ( Bakris, GL; Laffin, LJ; Liao, C; Majewski, C, 2016)
"Observational studies in primary hyperaldosteronism suggest a positive relationship between aldosterone and parathyroid hormone (PTH); however, interventions to better characterize the physiological relationship between the renin-angiotensin-aldosterone system (RAAS) and PTH are needed."2.79Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone. ( Adler, GK; Brown, JM; Garg, R; Garza, AE; Luther, JM; Pojoga, LH; Ruan, DT; Vaidya, A; Williams, GH; Williams, JS, 2014)
"The high prevalence of obstructive sleep apnea in patients with resistant hypertension could be mediated by an activation of the renin-angiotensin-aldosterone system."2.79A randomized controlled study of CPAP effect on plasma aldosterone concentration in patients with resistant hypertension and obstructive sleep apnea. ( Espinel, E; Ferrer, R; Lloberes, P; Martínez-Garcia, MA; Ramon, MA; Romero, O; Sampol, G; Segarra, A; Tovar, JL, 2014)
"Primary aldosteronism (PA) is an established cause of hypertension, whereas high-normal serum aldosterone levels have been linked to an increased risk for hypertension."2.78Evidence of primary aldosteronism in a predominantly female cohort of normotensive individuals: a very high odds ratio for progression into arterial hypertension. ( Chrousos, GP; Gouli, A; Kaltsas, G; Markou, A; Mitsakis, K; Papanastasiou, L; Pappa, T; Piaditis, GP; Prevoli, A; Tsiavos, V; Tsounas, P; Zografos, G, 2013)
"Inflammation is considered as a major effector of arterial damage brought about by salt excess in animal models."2.78Procalcitonin and the inflammatory response to salt in essential hypertension: a randomized cross-over clinical trial. ( Cutrupi, S; Leonardis, D; Mallamaci, F; Pizzini, P; Tripepi, G; Zoccali, C, 2013)
"Aldosterone breakthrough was observed in 22 of the subjects (55%)."2.78Effect of aldosterone breakthrough on albuminuria during treatment with a direct renin inhibitor and combined effect with a mineralocorticoid receptor antagonist. ( Fukuda, S; Sato, A, 2013)
"Primary aldosteronism is the most frequent cause of secondary hypertension and is associated with more prominent left ventricular hypertrophy and increased myocardial fibrosis."2.77Adrenalectomy reverses myocardial fibrosis in patients with primary aldosteronism. ( Chang, HW; Chueh, SC; Ho, YL; Lee, HH; Lee, JK; Lin, CY; Lin, LC; Lin, YH; Liu, YC; Lo, MT; Wu, KD; Wu, VC; Wu, XM, 2012)
"In patients with primary aldosteronism, adrenal vein sampling (AVS) is considered the only reliable technique to distinguish between unilateral and bilateral autonomous production of aldosterone, but agreement is lacking on the best criteria indicating successful cannulation and lateralization."2.75Impact of different diagnostic criteria during adrenal vein sampling on reproducibility of subtype diagnosis in patients with primary aldosteronism. ( Bertello, C; Daunt, N; Gordon, R; Leggett, D; Mengozzi, G; Mulatero, P; Rossato, D; Stowasser, M; Sukor, N; Veglio, F, 2010)
"Angiotensin-converting enzyme (ACE) inhibitors differ in their lipophilic/hydrophilic index that determines their tissue bioavailability and affinity to ACE, which may result in major differences in the degree of blockade of cardiac ACE."2.75Effects of ACE inhibitors on cardiac angiotensin II and aldosterone in humans: "Relevance of lipophilicity and affinity for ACE". ( Coletta, E; Davies, R; Haddad, H; Leenen, FH; Ruzicka, M; White, R, 2010)
"Aldosterone was positively related to PRA and progesterone."2.74The ovarian cycle as a factor of variability in the laboratory screening for primary aldosteronism in women. ( Di Cecco, P; Fommei, E; Ghione, S; Iervasi, A; Maffei, S; Ripoli, A; Turchi, S, 2009)
"Aldosterone production causes vascular injury and may occur despite the long-term administration of angiotensin converting enzyme-inhibitors (ACE-I) (ie, aldosterone breakthrough)."2.74Effects of ARB or ACE-inhibitor administration on plasma levels of aldosterone and adiponectin in hypertension. ( Hoshino, J; Hosoi, T; Iwasaki, T; Kawachi, K; Kurabayashi, M; Morishita, K; Nakamura, T; Ohyama, Y; Saito, T; Saito, Y, 2009)
"People with prehypertension are at risk of developing hypertension, being a biomarker for cardiovascular disease risk."2.73Bovine casein hydrolysate (c12 Peptide) reduces blood pressure in prehypertensive subjects. ( Cadée, JA; Chang, CY; Chen, CW; Chen, SL; Huang, CN; Wang, CK, 2007)
"Amiloride 40 mg was as effective as the other diuretics."2.73The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio. ( Ashby, MJ; Brown, MJ; Hood, SJ; Taylor, KP, 2007)
"We studied 30 patients with type 2 diabetes mellitus (mean age 43."2.73Gradual reactivation of vascular angiotensin I to angiotensin II conversion during chronic ACE inhibitor therapy in patients with diabetes mellitus. ( Morris, AD; Sharman, DC; Struthers, AD, 2007)
"Aldosterone is an important pathogenetic factor, independent of the renin-angiotensin system in cardiovascular and renal disease."2.73Aldosterone breakthrough during angiotensin II receptor blockade in hypertensive patients with diabetes mellitus. ( Karashima, S; Oda, N; Takata, H; Takeda, Y; Usukura, M; Yamagishi, M; Yamamoto, Y; Yoneda, T, 2007)
"Primary aldosteronism is a common cause of secondary hypertension associated with excess cardiovascular morbidities."2.72Diagnosis and treatment of primary aldosteronism. ( Bancos, I; Mulatero, P; Reincke, M; Scholl, UI; Stowasser, M; Williams, TA, 2021)
"Hypertension is highly prevalent in Black Africans and has been found to be associated with worse blood pressure (BP) control and more cardiovascular disease."2.72The importance of the epithelial sodium channel in determining salt sensitivity in people of African origin. ( Jones, E; Rayner, B, 2021)
"Primary aldosteronism (PA), the most common form of secondary hypertension, has been considered for decades as a "benign" form of hypertension, but evidences progressively built up to show that patients with PA had an excess rate of cardiovascular damage as compared to blood pressure-matched essential hypertensive patients."2.72The cardiovascular consequences of hyperaldosteronism. ( Cesari, M; Maiolino, G; Rossi, GP; Seccia, TM, 2021)
"Aldosterone is a mineralocorticoid hormone that controls body fluid and electrolyte balance."2.72Aldosterone, Inflammation, Immune System, and Hypertension. ( Ferreira, NS; Paradis, P; Schiffrin, EL; Tostes, RC, 2021)
"Primary aldosteronism (PA) is a common cause of secondary hypertension and is associated with worse cardiovascular outcomes."2.72Left ventricular remodeling and dysfunction in primary aldosteronism. ( Chang, YY; Chen, ZW; Hung, CS; Lin, YH; Pan, CT; Tsai, CH; Wu, VC, 2021)
"Metabolic syndrome is a cluster of conditions that increase the risk of cardiovascular diseases, and comprises obesity, hypertension, impaired glucose metabolism and dyslipidaemia."2.72The mineralocorticoid receptor-an emerging player in metabolic syndrome? ( Stowasser, M; Thuzar, M, 2021)
"Hyperaldosteronism can occur either as primary aldosteronism (renin-independent) or secondary aldosteronism (renin-dependent)."2.72[Hyperaldosteronism]. ( Scholl, UI, 2021)
"In adults, obesity is often associated with salt-sensitive hypertension."2.72Kidney and epigenetic mechanisms of salt-sensitive hypertension. ( Fujita, T; Kawarazaki, W, 2021)
"Primary aldosteronism, characterized by renin-independent aldosterone secretion from one or both adrenal glands, is the most common and modifiable form of secondary hypertension."2.72How common is primary aldosteronism? ( Hundemer, GL; Kline, GA; Leung, AA, 2021)
"Primary aldosteronism (PA) is one of the most frequent curable forms of secondary hypertension."2.72Functional Characteristic and Significance of Aldosterone-Producing Cell Clusters in Primary Aldosteronism and Age-Related Hypertension. ( Azizan, EA; Pauzi, FA, 2021)
"Primary aldosteronism (PA), a condition characterized by autonomous aldosterone hypersecretion, constitutes the most common cause of secondary hypertension."2.72Unravelling the Genetic Basis of Primary Aldosteronism. ( Charmandari, E; Markou, A; Mourtzi, N; Piaditis, GP; Sertedaki, A, 2021)
"Primary aldosteronism (PA) is the most common cause of secondary hypertension and is significantly under-diagnosed."2.72Therapeutic Outcomes with Surgical and Medical Management of Primary Aldosteronism. ( Fraker, DL; Wachtel, H, 2021)
"Primary aldosteronism (PA) is the most common cause of secondary hypertension."2.72Primary Aldosteronism: a Continuum from Normotension to Hypertension. ( Turcu, AF; Wannachalee, T, 2021)
"Rofecoxib caused an increase in BP compared to celecoxib; a change in recumbent systolic BP +/- SD (6."2.72Can the blood pressure effects of COX-2 selective inhibitors be explained by changes in plasma aldosterone levels? ( Aw, TJ; Billah, B; Krum, H; Liew, D; Morel-Kopp, MC; Schneider, HG; Tofler, GH, 2006)
" Group H showed significantly smaller furosemide dosage in the initial 3 days (H vs."2.71Synthetic human alpha-atrial natriuretic peptide improves the management of postoperative hypertension and renal dysfunction after the repair of abdominal aortic aneurysm. ( Akedo, H; Hayashi, Y; Hiraishi, T; Kobayashi, Y; Matsuda, H; Ohtani, M; Sawa, Y, 2003)
"The ARR threshold to screen for primary aldosteronism may be based on measurement of irR."2.71Active renin versus plasma renin activity to define aldosterone-to-renin ratio for primary aldosteronism. ( Ferrari, P; Nicod, J; Nussberger, J; Saner, E; Shaw, SG, 2004)
"Aldosterone antagonism has BP-independent effects on arterial stiffness."2.71Aldosterone-to-renin ratio, arterial stiffness, and the response to aldosterone antagonism in essential hypertension. ( Feely, J; Mahmud, A, 2005)
"Hypertension is the most common cardiovascular complication after liver transplantation."2.71Mechanisms of hypertension after liver transplantation. ( Alexander, GJ; Brown, MJ; Neal, DA; Wilkinson, IB, 2005)
"Hypertension is commonly associated with chronic renal disease in cats, and inappropriate activation of the renin-angiotensin-aldosterone system (RAAS) may contribute to the hypertensive state."2.70Effects of angiotensin-converting enzyme inhibition on plasma aldosterone concentration, plasma renin activity, and blood pressure in spontaneously hypertensive cats with chronic renal disease. ( Henik, RA; Steele, JL; Stepien, RL, 2002)
"Primary hyperaldosteronism was confirmed if plasma renin activity was <1."2.70Hyperaldosteronism among black and white subjects with resistant hypertension. ( Calhoun, DA; Nishizaka, MK; Thakkar, RB; Weissmann, P; Zaman, MA, 2002)
"Primary aldosteronism is a specifically treatable and potentially curable form of secondary hypertension."2.70Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism. ( Chiandussi, L; Milan, A; Morello, F; Mulatero, P; Paglieri, C; Rabbia, F; Veglio, F, 2002)
"Telmisartan is a new angiotensin receptor antagonist possessing potent, selective, and insurmountable inhibitory activity specific to the angiotensin II type 1 (AT 1 ) receptor."2.70Inhibitory effect of telmisartan on the blood pressure response to angiotensin II challenge. ( de Bruin, H; Jonkman, JH; Meinicke, T; Stangier, J; Su, CA; Tamminga, WJ; van Heiningen, PN; van Lier, JJ, 2001)
" In hypertensive patients, the long-term administration of olmesartan, a novel AT1 receptor antagonist, decreased both blood pressure and plasma angiotensin II levels."2.70Long-term effects of olmesartan, an Ang II receptor antagonist, on blood pressure and the renin-angiotensin-aldosterone system in hypertensive patients. ( Ichikawa, S; Takayama, Y, 2001)
"When amiloride was withdrawn for 2 weeks, there was a large increase in blood pressure of 17/8+/-4/2 mm Hg (systolic, P<0."2.70Amiloride, a specific drug for hypertension in black people with T594M variant? ( Baker, EH; Dong, Y; Duggal, A; Ireson, NJ; MacGregor, GA; Markandu, ND; Wood, M, 2002)
"Eprosartan was titrated from 200 mg b."2.69Effects of eprosartan versus enalapril in hypertensive patients on the renin-angiotensin-aldosterone system and safety parameters: results from a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group. ( Gavras, H; Gavras, I, 1999)
"Spironolactone was a highly effective antihypertensive agent in hypertensive patients who had a raised aldosterone/renin ratio."2.69Raised aldosterone to renin ratio predicts antihypertensive efficacy of spironolactone: a prospective cohort follow-up study. ( Jung, RT; Lim, PO; MacDonald, TM, 1999)
"In familial hyperaldosteronism type I, inheritance of a hybrid 11beta-hydroxylase/aldosterone synthase gene leads to ACTH-regulated overproduction of aldosterone (causing hypertension) and of "hybrid" steroids, 18-hydroxy- and 18-oxo-cortisol."2.69Treatment of familial hyperaldosteronism type I: only partial suppression of adrenocorticotropin required to correct hypertension. ( Bachmann, AW; Gordon, RD; Huggard, PR; Rossetti, TR; Stowasser, M, 2000)
"This study was designed to compare with placebo the dose-response of conjugated equine oestrogen (CEE) on blood pressure in hypertensive postmenopausal women."2.69Dose response effect of conjugated equine oestrogen on blood pressure in postmenopausal women with hypertension. ( Harvey, PJ; Molloy, D; Upton, J; Wing, LM, 2000)
"Losartan appears to be an effective anti-hypertensive agent in patients with mild to moderate hypertension."2.68Effects of losartan on the renin-angiotensin-aldosterone axis in essential hypertension. ( Bauer, IH; Lau-Sieckman, A; Reams, GP; Wu, Z, 1995)
" All patients received three dosing regimens administered in random order: (a) intravenous frusemide: 40 mg bolus then 40 mg h-1 for 3 h, (b) captopril: two 12."2.68The renin angiotensin aldosterone system and frusemide response in congestive heart failure. ( Cerimele, B; Greene, P; Reed, S; Ryan, T; Schwertschlag, U; Voelker, J; Weinberger, M, 1995)
"Neuropeptide Y (NPY) has been recently characterized as a circulating vasoconstrictor peptide which is co-stored with noradrenaline in sympathetic neurons."2.68[Concentration of neuropeptide Y in serum of patients with primary hypertension]. ( Halawa, B; Salomon, P, 1996)
"Essential hypertension is a very common disease in the world."2.68[Selected components of the kallikrein-kinin system and of the renin-angiotensin-aldosterone system in offspring of parents with hypertension]. ( Marzecka, J, 1996)
"Fludrocortisone was given daily for 1 week and circulating components of the plasma and tissue kallikrein-kinin systems and renin-angiotensin-aldosterone system were measured repeatedly."2.68Circulating kallikreins in normotensive and hypertensive humans: effects of mineralocorticoid administration. ( Ohman, KP, 1997)
"Fourteen subjects with untreated essential hypertension were subjected to 2-h water immersion (WI) study."2.67Regulation of sodium excretion in human hypertension: long-term effects of calcium antagonist and angiotensin converting enzyme inhibitor. ( Coruzzi, P; Mossini, GL; Musiari, L; Novarini, A, 1993)
"Losartan (DuP 753) is a novel orally active angiotensin II antagonist that lowers blood pressure."2.67Hemodynamic and humoral effects of the angiotensin II antagonist losartan in essential hypertension. ( Carroll, J; Grossman, E; Peleg, E; Rosenthal, T; Shamiss, A, 1994)
" Thus, this long-term study provides additional evidence that diuretics have a flat dose-response curve with respect to their antihypertensive efficacy, whereas lower doses might cause less pronounced activation of counter-regulatory systems."2.67Long-term diuretic therapy: effects of dose reduction on antihypertensive efficacy and counterregulatory systems. ( Ripka, O; Weisser, B, 1992)
" Blood pressure was dose-dependently reduced over the full 24-hour dosing period with more pronounced effects on day 8 than on day 1."2.67Hemodynamic and humoral effects of the novel calcium antagonist Ro 40-5967 in patients with hypertension. ( Belz, GG; Feifel, U; Halabi, A; Kirch, W; Kleinbloesem, CH; Pozenel, H; Schmitt, R; Schroeter, V; Welker, HA; Woittiez, AJ, 1992)
"These results show that a first-step treatment of hypertension with converting enzyme inhibitors permits better left ventricular function and improves exercise tolerance by way of renin-angiotensin-aldosterone system inhibition."2.67Comparisons of long-term effects between converting enzyme inhibitors and conventional therapy in treating mild to moderate hypertension. ( Chen, CY; Chiang, HT; Lin, M, 1991)
" Doxazosin produced rightward shifts of the PE pressor dose-response curves but had no effect on responses to AII."2.67Vascular pressor responses in treated and untreated essential hypertension. ( Donnelly, R; Elliott, HL; Howie, CA; Reid, JL; Sumner, DJ, 1990)
"Treatment with felodipine ER over 2 weeks increased sympathetic outflow as indicated by elevated plasma norepinephrine levels, whereas plasma epinephrine was mainly unaffected, as were plasma renin and aldosterone levels."2.67Catecholamines and the renin-angiotensin-aldosterone system during treatment with felodipine ER or hydrochlorothiazide in essential hypertension. ( Binner, L; Gabrielsen, F; Hombach, V; Koenig, W; Rosenthal, J; Sund, M, 1991)
" Perindopril alone tended to reduce serum and urinary thromboxane B2 (TxB2) and to raise urinary 6-ketoPGF1 alpha and PGE2 and inhibited serum ACE activity 24 h post dosing by about 85%."2.67Hemodynamic and humoral interactions between perindopril and indomethacin in essential hypertensive subjects. ( Abdel-Haq, B; Favilla, S; Magagna, A; Salvetti, A, 1991)
"Aldosterone levels were also increased after three months, but without a subsequent decrease."2.67Isradipine in the treatment of hypertension. Some additional effects observed during a one-year study. ( Mayer, O; Polivkova, H; Rottenborn, J, 1991)
"Nicardipine (80 mg/day) was given orally for 12 weeks and no dietary restrictions were imposed."2.67Efficacy of nicardipine slow release (SR) on hypertension, potassium balance and plasma aldosterone in idiopathic aldosteronism. ( Bisbocci, D; Chiandussi, L; Pinna, G; Piras, D; Rabbia, F; Veglio, F, 1990)
"Primary aldosteronism is currently considered to represent 5-13% of hypertension, yet fewer than 1% of patients with the disorder are ever diagnosed and treated."2.66Primary aldosteronism: Treatment of the disease, and new therapeutic approaches. ( Funder, J, 2020)
"Primary aldosteronism (PA), the most common cause of secondary hypertension, is a well-recognized condition that can lead to cardiovascular and renal complications."2.66Associations between primary aldosteronism and diabetes, poor bone health, and sleep apnea-what do we know so far? ( Loh, HH; Sukor, N, 2020)
"Primary aldosteronism (PA) is the most common potentially curable form of hypertension."2.66Prevalence, diagnosis and outcomes of treatment for primary aldosteronism. ( Reincke, M; Williams, TA; Yang, Y, 2020)
"Primary aldosteronism (PA) is the most common form of secondary hypertension affecting 5%-10% of patients with arterial hypertension."2.66Old and new genes in primary aldosteronism. ( Boulkroun, S; Fernandes-Rosa, FL; Zennaro, MC, 2020)
"Primary aldosteronism (PA) is the most common form of endocrine hypertension."2.66Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism. ( Gong, S; Meyer, LS; Reincke, M; Williams, TA, 2020)
"Primary aldosteronism (PA) is the most common cause of secondary hypertension."2.66The Potential Role of Aldosterone-Producing Cell Clusters in Adrenal Disease. ( Lim, JS; Rainey, WE, 2020)
"Conn, primary aldosteronism (PA) today is well established as a relevant cause of secondary hypertension and accounts for about 5-10 % of hypertensives."2.66Salt Appetite and its Effects on Cardiovascular Risk in Primary Aldosteronism. ( Adolf, C; Handgriff, L; Heinrich, DA; Reincke, M; Schneider, H, 2020)
"Hypokalemia is closely linked with the pathophysiology of primary aldosteronism (PA)."2.66Hypokalemia and the Prevalence of Primary Aldosteronism. ( Beuschlein, F; Gruber, S, 2020)
"Hypertension is characteristically associated with vascular dysfunction, cardiovascular remodelling, renal dysfunction, and stimulation of the sympathetic nervous system."2.66Oxidative Stress: A Unifying Paradigm in Hypertension. ( Alves-Lopes, R; Camargo, LL; Montezano, AC; Neves, KB; Rios, FJ; Touyz, RM, 2020)
"Primary aldosteronism (PA) is the most common cause of secondary hypertension."2.66[Update and Research Progress in the Diagnosis of Primary Aldosteronism]. ( Chen, T; Li, YM; Ren, Y; Tian, HM, 2020)
"Primary aldosteronism is associated with higher cardiovascular and renal morbidity and mortality than essential hypertension in age- and sex-matched patients with the same degree of blood pressure elevation."2.66Treatment of primary hyperaldosteronism. ( Araujo-Castro, M, 2020)
"The landscape of primary aldosteronism has evolved to recognize that it is a prevalent syndrome of renin-independent aldosterone production that contributes to the pathogenesis of hypertension and cardiovascular disease."2.66Evolution of the Primary Aldosteronism Syndrome: Updating the Approach. ( Carey, RM; Vaidya, A, 2020)
"Primary hyperaldosteronism (PA) is a well-known cause of hypertension although its exact prevalence amongst patients with apparent essential hypertension has been a matter of debate."2.66Five Reasons for the Failure to Diagnose Aldosterone Excess in Hypertension. ( Chrousos, GP; Kaltsas, G; Markou, A; Piaditis, GP, 2020)
"Captopril when dosed to lower diastolic blood pressure 5-7 mm Hg did not significantly affect GFR, RPF or RVR."2.66Preliminary observations of the acute effects of selective serum thromboxane inhibition and angiotensin converting enzyme inhibition on blood pressure and renal hemodynamics in hypertensive humans. ( Douglas, FL; Hoover, N; Klassen, DK; Weir, MR, 1989)
" In the clinical development of an antihypertensive drug, the earlier use of such within-patient studies, with the random insertion of one placebo period between the active periods, should help in the dose-response curve search."2.66Crossover design for the dose determination of an angiotensin converting enzyme inhibitor in hypertension. ( Bellet, M; Corvol, P; Guyene, TT; Ménard, J; Sassano, P; Serrurier, D, 1989)
"Bopindolol is a new long-acting, nonselective beta-adrenoceptor antagonist with partial agonist activity."2.66The clinical pharmacology of bopindolol, a new long-acting beta-adrenoceptor antagonist, in hypertension. ( Boomsma, F; Derkx, FH; Man in 't Veld, AJ; Mulder, P; Schalekamp, MA; van den Meiracker, AH; van Eck, HJ, 1987)
"Aldosterone changes on treatment were marginal and nonsignificant."2.66Effects of fosenopril, a once-daily angiotensin-converting enzyme inhibitor, on resting and exercise-induced changes of blood pressure, hormonal variables, and plasma potassium in essential hypertension. ( Cervenka, J; Dineen, M; O'Connor, DT; Sullivan, PA, 1988)
"Celiprolol is a newly developed cardioselective beta-blocking agent with mild beta 2-agonist and weak alpha 2-antagonist properties."2.66Effects of celiprolol on plasma renin, aldosterone, norepinephrine and epinephrine in primary hypertension. ( DeQuattro, V; Hernandez, PH; Kimura, S; Lee, DD, 1988)
" Further measurements were made during a series of intensive study days, and the most important additional finding was a pharmacokinetic interaction that resulted in increased peak concentrations and bioavailability of prazosin."2.66The combination of prazosin and verapamil in the treatment of essential hypertension. ( Campbell, L; Elliott, HL; Meredith, PA; Reid, JL, 1988)
"Nicardipine appears to blunt the secretion of aldosterone responding to an increased PRA possibly through its calcium-antagonizing action."2.66Multiple oral doses of nicardipine, a calcium-entry blocker: effects on renal function, plasma renin activity, and aldosterone concentration in mild-to-moderate essential hypertension. ( Aoyagi, K; Baba, T; Ishizaki, T; Murabayashi, S; Takebe, K; Tamasawa, N, 1987)
"Domperidone pretreatment prevented the GFR increase induced by nicardipine and increased the noradrenaline response (+107%), but did not change the other actions of nicardipine."2.66Haemodynamic (systemic and renal) and humoral interactions between nicardipine and domperidone in hypertensives. ( Lucarini, AR; Salvetti, A, 1987)
" The mean supine BP 24 hours post dosing were 177/110 mmHg (placebo), 173/109 mmHg (propranolol) and 164/100 mmHg (atenolol)."2.66Atenolol or propranolol in hypertensive patients poorly controlled on captopril and frusemide. ( Lovell, HG; Petrie, JC; Robb, OJ; Webster, J; Witte, K, 1987)
"Guanfacine monotherapy was again shown to be an effective initial treatment for mild essential hypertension with no adverse influence on serum lipids."2.66Guanfacine as monotherapy for systemic hypertension. ( Blackshear, JL; Fillingim, JM; Strauss, A; Strauss, M, 1986)
" The cardiovascular responses to the chronic administration of CL 115347 were studied in a double-blind, placebo-controlled trial in 26 subjects with essential hypertension (16 given drug, 10 placebo) maintained on a 100-mEq sodium diet."2.66Prostaglandin E2 analogue elicits renal and hormonal compensatory mechanisms in human hypertension. ( Akester, J; Black, HR; Dzau, VJ; Francis, C; Given, BD; Koury, K; Lasseter, K; Mickiewicz, C; Morray, RL; Vita, NA, 1986)
"Captopril was administered orally in 2 daily doses of 25 to 200 mg."2.65Uncontrollable hypertension in patients on hemodialysis: long-term treatment with captopril and salt subtraction. ( Brunner, HR; Gavras, H; Guignard, JP; Turini, GA; Waeber, B; Wauters, JP, 1981)
" The results obtained from single-blind, placebo-controlled studies indicate that indapamide is a safe and effective agent to use in lowering the blood pressure of hypertensive patients with normal renal function, those with various degrees of renal impairment, and those who are undergoing long-term maintenance hemodialysis."2.65Clinical efficacy, safety, and pharmacokinetics of indapamide in renal impairment. ( Acchiardo, SR; Skoutakis, VA, 1983)
"In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)."2.65[Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984)
"Hypertension was not caused by 5 days of administration of aldosterone, 18-hydroxydeoxycorticosterone (18-OH-DOC) at 1 mg/day, or deoxycorticosterone (DOC) at 30 mg/day."2.64Mineralocorticoid hypertension in childhood. ( Levine, LS; New, MI, 1977)
"Labetalol was more effective in lowering blood pressure but less effective in reducing pulse rate of plasma angiotensin II concentration."2.64Effect of blood pressure angiotensin II and aldosterone concentrations during treatment of severe hypertension with intravenous labetalol: comparison with propranolol. ( Brown, JJ; Fraser, R; Lever, AF; Morton, JJ; Robertson, JI; Rosei, EA; Trust, PM, 1976)
"Treatment with propranolol resulted in marked suppression of the plasma renin activity (1."2.64Intrapatient comparison of treatment with chlorthalidone, spironolactone and propranolol in normoreninemic essential hypertension. ( Benraad, TJ; Drayer, JI; Festen, J; Kloppenborg, PW; van't Laar, A, 1975)
"Hypertension is a significant public health problem."2.61Monogenic hypertension. ( Bertelli, M; Dallavilla, T; Guerri, G; Krasi, G; Marinelli, C; Perrone, M; Precone, V; Romeo, F; Stuppia, L; Zulian, A, 2019)
"Low-renin hypertension affects 30% of hypertensive patients."2.61Low-Renin Hypertension. ( Athimulam, S; Bancos, I; Lazik, N, 2019)
"Resistant hypertension is a common clinical entity, defined as suboptimal blood pressure response to multiple therapies after excluding medication nonadherence and secondary forms of hypertension."2.61Resistant Hypertension: A Clinical Perspective. ( Gubbi, S; Hannah-Shmouni, F; Koch, CA; Spence, JD; Stratakis, CA, 2019)
"Primary aldosteronism (PA) is a common, but frequently overlooked, cause of arterial hypertension and excess cardiovascular events, particularly atrial fibrillation."2.61Primary Aldosteronism: JACC State-of-the-Art Review. ( Rossi, GP, 2019)
"Refractory hypertension is defined as uncontrolled blood pressure despite use of ≥5 antihypertensive agents of different classes, including a long-acting thiazide-like diuretic and an MR (mineralocorticoid receptor) antagonist, at maximal or maximally tolerated doses."2.61Treatment of Resistant and Refractory Hypertension. ( Acelajado, MC; Calhoun, DA; Hughes, ZH; Oparil, S, 2019)
"Primary aldosteronism (PA) is the most prevalent cause of secondary hypertension (3%-32% of hypertensive patients)."2.61The aldosterone to renin ratio in the diagnosis of primary aldosteronism: Promises and challenges. ( Denieffe, S; Fitzgibbon, MC; Griffin, TP; O'Shea, PM, 2019)
"Primary aldosteronism is the most common form of secondary hypertension."2.58Overview of aldosterone-related genetic syndromes and recent advances. ( Boulkroun, S; Fernandes-Rosa, FL; Zennaro, MC, 2018)
"Moreover, primary aldosteronism patients are exposed to an increased risk of cardio and cerebrovascular events and metabolic comorbidities compared with patients affected by essential hypertension."2.58Primary aldosteronism in the primary care setting. ( Buffolo, F; Monticone, S; Mulatero, P; Tetti, M, 2018)
"All physicians who treat hypertension should routinely screen appropriate patients for PA."2.58Primary Aldosteronism: Practical Approach to Diagnosis and Management. ( Auchus, RJ; Byrd, JB; Turcu, AF, 2018)
"Aldosterone has also been shown to increase blood pressure by a direct activation of the sympathetic nervous system, to cause endothelial and vascular smooth muscle cell dysfunction, myocardial remodeling and fibrosis, and to have pro-arrhythmogenic actions in the heart."2.55Mineralocorticoid Receptor Blockade in End-Stage Renal Disease. ( Gosmanova, EO; Lyubarova, R, 2017)
" An assessment of dose-response was also undertaken."2.55The association between consistent licorice ingestion, hypertension and hypokalaemia: a systematic review and meta-analysis. ( Eslick, EM; Eslick, GD; Penninkilampi, R, 2017)
"Primary aldosteronism (PA) is the most common form of secondary hypertension and is critical to identify because when caused by an aldosterone-producing adenoma (APA) or another unilateral form, it is potentially curable, and even when caused by bilateral disease, antihypertensives more specific to PA treatment can be employed (ie, aldosterone antagonists)."2.55Adrenal venous sampling for primary aldosteronism: laboratory medicine best practice. ( Holmes, DT; Kline, G, 2017)
"Hyperaldosteronism is the leading cause of secondary hypertension with up to 80% due to APA, statistically the most common functioning adrenal nodule."2.55Radiofrequency ablation treatment for aldosterone-producing adenomas. ( Faintuch, S; Sacks, AC; Sacks, BA, 2017)
"Primary aldosteronism (PA) is associated with a high rate of cardio- and cerebrovascular complications and metabolic alterations."2.53Issues in the Diagnosis and Treatment of Primary Aldosteronism. ( Buffolo, F; Burrello, J; Giraudo, G; Monticone, S; Mulatero, P; Schiavone, D; Tetti, M; Veglio, F, 2016)
"Aldosterone also promotes collagen synthesis, which leads to increased arterial stiffness and elevation of blood pressure."2.53Resistant Hypertension and the Pivotal Role for Mineralocorticoid Receptor Antagonists: A Clinical Update 2016. ( Duprez, DA; Epstein, M, 2016)
"Obese subjects often exhibit hyperaldosteronism, with increased salt sensitivity of blood pressure (BP)."2.53The Role of Aldosterone in Obesity-Related Hypertension. ( Fujita, T; Kawarazaki, W, 2016)
"Primary aldosteronism (PA) is the most common secondary cause of hypertension, accounting for 10 % of hypertensives and 20 % of those with drug-resistant hypertension."2.53Hyperaldosteronism: Screening and Diagnostic Tests. ( Fallo, F; Sabbadin, C, 2016)
"Primary aldosteronism (PA), characterized by the inappropriate and abnormal adrenal secretion of aldosterone, is the most common cause of secondary hypertension."2.53Hyperaldosteronism: How to Discriminate Among Different Disease Forms? ( Buffolo, F; Burrello, J; Crudo, V; Monticone, S; Mulatero, P; Tetti, M; Veglio, F, 2016)
"Pseudohyperaldosteronism is characterized by a clinical picture of hyperaldosteronism with suppression of renin and aldosterone."2.53Syndromes that Mimic an Excess of Mineralocorticoids. ( Armanini, D; Sabbadin, C, 2016)
"Obesity is a serious health hazard with rapidly increasing prevalence in the United States."2.53Obesity, hypertension and aldosterone: is leptin the link? ( Bollag, WB; Xie, D, 2016)
"Primary aldosteronism (PA) is a condition well worth detecting because it is a common cause of hypertension and is associated with excessive morbidity for the degree of hypertension and reduced quality of life, all of which can be abrogated with specific surgical or medical treatment."2.52Update in primary aldosteronism. ( Stowasser, M, 2015)
"A brief introduction to primary aldosteronism is provided."2.52Laboratory challenges in primary aldosteronism screening and diagnosis. ( Cavalier, E; Don-Wauchope, AC; Holmes, DT; Raizman, JE; Rehan, M, 2015)
"Hypertension is one of the most common cardiovascular diseases during pregnancy."2.52[Hypertension in the course of primary aldosteronism during pregnancy]. ( Chudek, J; Maruniak-Chudek, I; Olszanecka-Glinianowicz, M; Sikora, J; Wyskida, K; Wyskida, M, 2015)
"Primary aldosteronism is one of the commonly identified causes of hypertension and is treatable and/or potentially curable."2.52Mineralocorticoid and apparent mineralocorticoid syndromes of secondary hypertension. ( Ardhanari, S; Chaudhary, K; Kannuswamy, R; Lockette, W; Whaley-Connell, A, 2015)
"Obesity is a multifactorial disease associated with hypertension."2.52Reviving the use of aldosterone inhibitors in treating hypertension in obesity. ( Belin De Chantemèle, EJ; Huby, AC, 2015)
"Primary aldosteronism, caused by autonomous secretion of aldosterone by the adrenals, is estimated to account for at least 5% of hypertension cases."2.52Pharmacological treatment of aldosterone excess. ( Deinum, J; Lenders, JW; Riksen, NP, 2015)
"Primary aldosteronism (PA) is characterized by autonomic aldosterone production, usually leading to severe hypertension and hypokalaemia."2.52[Primary aldosteronism: new insights into familial forms]. ( Claahsen van der Grinten, HL; Danser, AH; Deinum, J; van den Meiracker, AH; van der Linde, AA, 2015)
"Obesity is epidemic and is associated with increased blood pressure, which often manifests as treatment-resistant hypertension."2.50A critical review of the evidence supporting aldosterone in the etiology and its blockade in the treatment of obesity-associated hypertension. ( Brook, RD; Byrd, JB, 2014)
"Indeed, hypertension is surgically curable in a minority of patients, mostly in patients with aldosterone-secreting adenomas or with pheochromocytomas or functional paragangliomas."2.50[Presentations and management of adrenal hypertension]. ( Amar, L; Azizi, M; Giavarini, A; Lorthioir, A; Plouin, PF, 2014)
"Heart failure is a complex syndrome that affects almost all organs and systems of the body."2.50[Organ damage and cardiorenal syndrome in acute heart failure]. ( Casado Cerrada, J; Pérez Calvo, JI, 2014)
" The dose-response relationship for natriuresis with spironolactone has not been explored completely as to its combination therapy responses."2.50Aldosterone and volume management in hypertensive heart disease. ( Sica, DA, 2014)
"Other than treatment for weight loss, treatment of hypertension with specific antihypertensive medications that block or reduce aldosterone action are appropriate in obese patients."2.50Increased aldosterone: mechanism of hypertension in obesity. ( Flynn, C, 2014)
"Hypertension (HTN) and obstructive sleep apnea (OSA) are coexistent in millions of people, and both have been associated with heart disease, stroke, and premature death."2.50Bidirectional relationship of hypertension with obstructive sleep apnea. ( Jhamb, M; Unruh, M, 2014)
"Resistant hypertension is a clinically distinct subgroup of hypertension defined by the failure to achieve blood pressure control on optimal dosing of at least 3 antihypertensive medications of different classes, including a diuretic."2.50Pathophysiology and treatment of resistant hypertension: the role of aldosterone and amiloride-sensitive sodium channels. ( Calhoun, DA; Judd, EK; Warnock, DG, 2014)
"Hypertension is traditionally considered a disease in which elevated blood pressure contributes to inflammation and activation of the immune system, leading to cardiovascular injury and end-organ damage."2.49Immune system alterations by aldosterone during hypertension: from clinical observations to genomic and non-genomic mechanisms leading to vascular damage. ( Barake, MF; Campino, C; Fardella, CE; Kalergis, AM; Letelier, NA; Muñoz-Durango, N, 2013)
"Aldosterone plays a major role in the regulation of sodium and potassium homeostasis and blood pressure."2.49Genetics of mineralocorticoid excess: an update for clinicians. ( Boulkroun, S; Rickard, AJ; Zennaro, MC, 2013)
" of public health relevance) on BP and whether there was a dose-response relationship; (2) the effect on BP by sex and ethnic group; (3) the effect on plasma renin activity, aldosterone, noradrenaline, adrenaline, cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and triglycerides."2.49Effect of longer-term modest salt reduction on blood pressure. ( He, FJ; Li, J; Macgregor, GA, 2013)
"Aldosterone has been found to be associated with cardiovascular toxicity."2.49Diagnosis and management of primary aldosteronism: an updated review. ( Chang, CC; Chao, CT; Chueh, SJ; Kuo, CC; Lin, YH; Pimenta, E; Stowasser, M; Wu, KD; Wu, VC, 2013)
"Aldosterone is a downstream effector of angiotensin II in the renin-angiotensin-aldosterone system and binds to the mineralocorticoid receptor."2.49Aldosterone receptor antagonists: current perspectives and therapies. ( Ahmed, MI; Calhoun, DA; Clark, D; Guichard, JL, 2013)
"Hypertension is an established risk factor for stroke, premature coronary artery disease and heart failure."2.49Aldosterone synthase inhibition in hypertension. ( Andersen, K, 2013)
"The identification of primary aldosteronism as a common cause of resistant hypertension is a significant advance in our ability to care for patients with hypertension."2.49Endocrine and hypertensive disorders of potassium regulation: primary aldosteronism. ( Weiner, ID, 2013)
"Primary aldosteronism (PA) is now recognized as the most frequent form of secondary arterial hypertension."2.49Diagnosis and treatment of unilateral forms of primary aldosteronism. ( Burrello, J; Crudo, V; Galmozzi, M; Loiacono, M; Monticone, S; Mulatero, P; Tizzani, D; Veglio, F; Versace, K; Viola, A, 2013)
"Primary aldosteronism (PA) seems to be a pathogenetically heterogenous disease."2.49Primary aldosteronism: a new insight into pathogenesis, diagnosis, and treatment in hypertensive patients. ( Hyla-Klekot, L; Kokot, F, 2013)
" An 8-week placebo-controlled dose-response study on patients with Stage 1 and 2 essential hypertension reported an optimal decrease in BP with a dose of 1 mg LCI699 q."2.49Aldosterone synthase inhibition in humans. ( Amar, L; Azizi, M; Menard, J, 2013)
"Primary aldosteronism (PA) has a prevalence in the general hypertensive population from 5 to 10%, and is widely recognized as the most frequent form of secondary hypertension."2.48Primary aldosteronism: who should be screened? ( Burrello, J; Crudo, V; Galmozzi, M; Monticone, S; Mulatero, P; Tizzani, D; Veglio, F; Viola, A, 2012)
"The MR-associated hypertension is classified into two subtypes, that with elevated plasma aldosterone levels and that with normal plasma aldosterone levels."2.48Mineralocorticoid receptor-associated hypertension and its organ damage: clinical relevance for resistant hypertension. ( Itoh, H; Shibata, H, 2012)
"A close association exists between hyperaldosteronism, RHTN, and obstructive sleep apnea (OSA) based upon recent studies which indicate that OSA is worsened by aldosterone-mediated fluid retention."2.48Resistant hypertension and aldosterone: an update. ( Ahmed, MI; Calhoun, DA; Clark, D, 2012)
" The observation of reduced nitric oxide bioavailability in hyperaldosteronism implied the generation of oxidative stress by aldosterone."2.48Aldosterone, oxidative stress, and NF-κB activation in hypertension-related cardiovascular and renal diseases. ( Queisser, N; Schupp, N, 2012)
"Addition of MR antagonists to standard treatment for hypertension and cardiac or renal disease decreases end-organ pathology and sympathetic nerve activation (SNA), and increases quality of life indices."2.48The ubiquitous mineralocorticoid receptor: clinical implications. ( Gomez-Sanchez, CE; Gomez-Sanchez, CM; Gomez-Sanchez, EP; Hawkins, UA, 2012)
"Endocrine hypertension is the most common cause of secondary hypertension affecting ~3 % of the population, with primary hyperaldosteronism and pheochromocytoma being the principal conditions."2.48[Update on endocrine hypertension]. ( Al-Salameh, A; Chanson, P; Cohen, R; Plouin, PF, 2012)
"Primary hyperaldosteronism (PHA) is characterized by an increased Aldosterone synthesis which is independent of the Renin-Angiotensin-Aldosterone-System (RAAS)."2.48[Primay hyperaldosteronism--diagnostic and treatment]. ( Beuschlein, F; Potthoff, SA; Vonend, O, 2012)
"Patients with treatment-resistant hypertension usually have OSA and have had a good antihypertensive response to spironolactone."2.47Antihypertensive therapy for patients with obstructive sleep apnea. ( Milic, M; Sun, P; Ziegler, MG, 2011)
"Aldosterone antagonists have been highly successful in treating congestive heart failure and resistant hypertension."2.47Mineralocorticoid receptor blockade in chronic kidney disease. ( Bomback, AS; Klemmer, PJ; Volk, MJ, 2011)
"Conversely, hypothyroidism is accompanied by a marked decrease in sensitivity to sympathetic agonists with an increase of peripheral vascular resistance and arterial stiffness."2.47Arterial hypertension and thyroid disorders: what is important to know in clinical practice? ( Al-Nahhas, A; Armigliato, M; Beltramello, G; Grassetto, G; Marzola, MC; Mazza, A; Montemurro, D; Rampin, L; Rubello, D; Zorzan, S; Zuin, M, 2011)
"In the setting of primary aldosteronism, elevated aldosterone levels are associated with increased blood pressure."2.46Aldosterone and arterial hypertension. ( Obermayer-Pietsch, B; Pieber, TR; Pilz, S; Ritz, E; Tomaschitz, A, 2010)
"Aldosterone was in the past considered only as a prohypertensinogenic agent."2.46Aldosterone in uremia - beyond blood pressure. ( Koleganova, N; Ritz, E, 2010)
"Obesity is a major risk factor for the development of hypertension."2.46Drug mechanisms to help in managing resistant hypertension in obesity. ( Danser, JA; Jansen, PM; Spiering, W; van den Meiracker, AH, 2010)
"Primary aldosteronism (PA) is a common cause of arterial hypertension: in the PA Prevalence in Hypertensives (PAPY) Study, the prevalence of PA was 11."2.46Prevalence and diagnosis of primary aldosteronism. ( Rossi, GP, 2010)
"Primary aldosteronism (PA) is one of the common forms of curable hypertension."2.46Cardiovascular and renal damage in primary aldosteronism: outcomes after treatment. ( Catena, C; Colussi, G; Di Fabio, A; Sechi, LA, 2010)
"Low-renin hypertension is a common type of resistant hypertension and is often associated with increased sodium retention."2.45Molecular and clinical investigations in patients with low-renin hypertension. ( Brown, MJ; Mackenzie, IS, 2009)
"Aldosterone plays an important role in electrolyte and blood pressure homeostasis."2.45Altered corticosteroid biosynthesis in essential hypertension: A digenic phenomenon. ( Alvarez-Madrazo, S; Connell, JM; Davies, E; Fraser, R; Freel, EM; Mackenzie, SM, 2009)
"Aldosterone is an adrenal hormone that regulates sodium, fluid, and potassium balance."2.45Aldosterone and cardiovascular disease. ( Calhoun, DA; Gaddam, KK; Husain, S; Pimenta, E, 2009)
"Primary hyperaldosteronism is a growing cause of apparently essential hypertension (until 15 % of patients with hypertension)."2.45[Primary hyperaldosteronisms: from diagnosis to treatment]. ( Carnaille, B; Douillard, C; Mounier-Vehier, C; Wémeau, JL, 2009)
"Eplerenone has been reported to have anti-hypertensive and protective effects on cardiovascular and renal injury in salt-sensitive hypertensive animal models, such as the Dahl salt-sensitive (DS) hypertensive rat and leptin receptor-deficient spontaneously hypertensive rat (SHR/cp)."2.45Effects of eplerenone, a selective mineralocorticoid receptor antagonist, on clinical and experimental salt-sensitive hypertension. ( Takeda, Y, 2009)
"Aldosterone has been found to accelerate the increase in left ventricular mass in patients with hypertension."2.45Resistant hypertension: who and how to evaluate. ( Acelajado, MC; Calhoun, DA, 2009)
"Aliskiren is a new renin inhibitor that block the RAAS at its origin."2.45Aliskiren: a new inhibitor of renin-angiotensin aldosterone system activity. ( Dalla Vestra, M; Masiero, A; Simioni, N, 2009)
"Primary aldosteronism is the most common cause of mineralocorticoid-induced hypertension, and MR antagonism offers the best prospect for achieving therapeutic goals."2.44Mineralocorticoid antagonism and cardiac hypertrophy. ( Nagata, K, 2008)
"Features of visceral obesity and obstructive sleep apnea that may stimulate aldosterone secretion are described here."2.44Obesity, sleep apnea, aldosterone, and hypertension. ( Goodfriend, TL, 2008)
"Primary aldosteronism (PA) is a known cause of hypertension."2.44[Primary aldosteronism]. ( Carvajal, CA; Fardella, CE; Mosso, LM, 2008)
"Aldosterone has also been demonstrated to be a major factor in target organ damage independent of its effects on blood pressure."2.44Aldosterone as an independent factor in cerebrovascular damage. ( Bertello, C; Caserta, M; Giraudo, G; Morello, F; Mulatero, P; Schiavone, D; Veglio, F; Verhovez, A, 2008)
" Although the exact incidence of resistant hypertension is not established, estimates derived from recent outcome studies including the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT), Valsartan Antihypertensive Long-term Use Evaluation (VALUE), and Controlled Onset Verapamil Investigation of Cardiovascular End Points (CONVINCE) emphasize that this condition may be more common than previously thought."2.44Resistant hypertension: prevalence and evolving concepts. ( Epstein, M, 2007)
"Aldosterone has also been shown to exert a number of effects in the central nervous system."2.44Aldosterone and the vasculature: mechanisms mediating resistant hypertension. ( Duprez, DA, 2007)
"Primary hyperaldosteronism is the most common secondary form of hypertension."2.44[Diagnosis of primary hyperaldosteronism]. ( Bidlingmaier, M; Diederich, S; Quinkler, M; Reincke, M, 2007)
"Human hypertension affects affects more than 20% of the adult population in industrialized countries, and it is implicated in millions of deaths worldwide each year from stroke, heart failure and ischemic heart disease."2.44Genetics of arterial hypertension and hypotension. ( Rimmbach, C; Rosskopf, D; Schäfers, R; Schürks, M, 2007)
"More than 80% of patients with type 2 diabetes mellitus develop hypertension, and approx."2.44Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions. ( Savoia, C; Schiffrin, EL, 2007)
" Moreover, ACE gene polymorphisms contribute to the modulation and adequacy of the neurohormonal response to long-term ACE inhibition, at least in patients with CHF (up to 45% of CHF patients have elevated Ang II levels despite the long-term use of an ACEI) or diabetes."2.44Angiotensin II reactivation and aldosterone escape phenomena in renin-angiotensin-aldosterone system blockade: is oral renin inhibition the solution? ( Athyros, VG; Kakafika, AI; Karagiannis, A; Mikhailidis, DP; Tziomalos, K, 2007)
"Aldosterone is an important mediator in the pathogenesis of heart failure, and increased plasma aldosterone levels are associated with a poor prognosis."2.44Drug insight: aldosterone-receptor antagonists in heart failure--the journey continues. ( Francis, GS; Kalidindi, SR; Tang, WH, 2007)
"Primary aldosteronism has been shown to represent 8-13% (rather than <1%) of unselected hypertensive patients, and patients with primary aldosteronism to have higher indices of cardiovascular damage than controls of the same age, sex, and BP status."2.44The role of aldosterone and mineralocorticoid receptors in cardiovascular disease. ( Funder, JW, 2007)
"Overweight and obesity are associated with arterial hypertension."2.44The association of aldosterone with obesity-related hypertension and the metabolic syndrome. ( Bochud, M; Burnier, M; Vogt, B, 2007)
"Primary aldosteronism is a relatively common form of secondary hypertension -- affecting 5 to 10% of all patients with hypertension."2.44Adrenal causes of hypertension: pheochromocytoma and primary aldosteronism. ( Young, WF, 2007)
"Individuals with primary aldosteronism make up a substantial proportion of those with hypertension."2.44Hyperaldosteronism: a commonly occurring underlying feature of essential hypertension and the metabolic syndrome? ( Chun, TY; Pratt, JH, 2007)
"The syndrome of primary aldosteronism, however, encompasses a wide spectrum of disorders that will require better definition."2.44Aldosterone and refractory hypertension. ( Nyirenda, MJ; Padfield, PL, 2007)
"Aldosterone plays a significant role in the pathogenesis of arterial hypertension and renal disease."2.44Aldosterone and progression of renal disease. ( Wenzel, U, 2008)
"Hyperaldosteronism is now recognized as the most common secondary cause and all patients with resistant hypertension should be screened with a plasma aldosterone-renin ratio even if the serum potassium level is normal."2.44Resistant hypertension and aldosteronism. ( Calhoun, DA; Pimenta, E, 2007)
"Hypertension is frequently found in endogenous Cushing's Syndrome (CS)."2.44Endocrine arterial hypertension: diagnostic approach in clinical practice. ( Armigliato, M; Cuppini, S; Mazza, A; Pessina, AC; Rempelou, P; Rubello, D; Zamboni, S; Zennaro, R, 2008)
"Aldosterone was also involved in the podocyte damage and proteinuria of metabolic syndrome model SHR/NDmcr-cp."2.44Aldosterone and glomerular podocyte injury. ( Fujita, T; Nagase, M, 2008)
"Torcetrapib was the first CETP inhibitor to enter a large-scale, prospective, placebo-controlled interventional trial, which was prematurely terminated in December 2006 because of excess cardiovascular and noncardiovascular mortality in the active treatment group."2.44Spotlight on HDL-raising therapies: insights from the torcetrapib trials. ( Chapman, MJ; Guérin, M; Kontush, A, 2008)
"Metabolic syndrome is an aggregation of hypertension, diabetes and dyslipidaemia."2.44Aldosterone in salt-sensitive hypertension and metabolic syndrome. ( Fujita, T, 2008)
"Obesity is strongly associated with hypertension and cardiovascular disease."2.43Obesity-associated hypertension: new insights into mechanisms. ( Correia, ML; Haynes, WG; Mark, AL; Rahmouni, K, 2005)
"Hypertension is a complex genetic disorder caused by interplay between several "risk" genes and environmental factors (genetic heritability approximately 30%)."2.43Genetics of human hypertension. ( Agarwal, A; Fisher, ND; Williams, GH, 2005)
"Aldosterone plays an important role in the pathophysiology of sodium/potassium and water homeostasis of the body."2.43Cardiovascular effects of aldosterone. ( Murin, J, 2005)
"The use of ARAs for the treatment of myocardial failure and selected cases of hypertension, in combination with the current therapy, has been strongly supported by trials such as the Randomized Aldactone Evaluation Study (RALES) and the Eplerenone Neurohormonal Efficacy and Survival Study (EPHESUS)."2.43Aldosterone receptor antagonists: biology and novel therapeutic applications. ( Magni, P; Motta, M, 2005)
"Primary aldosteronism is a rare cause of hypertension."2.43[Hypertension due to primary aldosteronism]. ( Bovy, C; Delanaye, P; Hamoir, E; Krzesinski, JM; Maweja, S; Radermecker, RP, 2005)
"Aldosterone plays an important role in the pathogenesis of cardiovascular disease."2.43Role of cardiovascular aldosterone in hypertension. ( Takeda, Y, 2005)
"In primary and secondary aldosteronism, aldosterone synthesis continues despite volume expansion and causes hypertension."2.43Miscellaneous endocrine causes of hypertension. ( Auchus, RJ, 2005)
"Obesity is strongly associated with arterial hypertension."2.43Mineralocorticoid-stimulating activity of adipose tissue. ( Bornstein, SR; Ehrhart-Bornstein, M; Lamounier-Zepter, V, 2005)
"Primary aldosteronism is a much more common cause of secondary hypertension than once suspected, accounting for approximately 10% of cases."2.43The pharmacological treatment of primary aldosteronism. ( Bouloux, PM; Janmohamed, S, 2006)
"Hypertension is often associated clinically with diabetes as part of the insulin-resistance syndrome or as a manifestation of renal disease."2.43Hypertension and diabetes: role of the renin-angiotensin system. ( Cooper, ME; Jandeleit-Dahm, K, 2006)
"Normokalaemic manifestation of primary aldosteronism is a frequent cause of secondary hypertension."2.43Screening for primary aldosteronism. ( Reincke, M; Schirpenbach, C, 2006)
"Surgically correctable forms of primary aldosteronism are generally held to be less common than forms requiring medical therapy."2.43Surgically correctable hypertension caused by primary aldosteronism. ( Rossi, GP, 2006)
"Endocrine hypertension is a term used for states in which hormone derangements result in clinically significant hypertension."2.43Incidentally discovered masses in hypertensive patients. ( Cicala, MV; Mantero, F; Sartorato, P, 2006)
"Primary aldosteronism (PA) is a form of surgically curable secondary hypertension."2.43[Screening tests and diagnostic examinations of hypertensives for primary aldosteronism]. ( Nishikawa, T; Omura, M, 2006)
"Arterial hypertension is one of the major coronary risk factors for cardiovascular diseases."2.43[Hypertension in postmenopausal women --selected pathomechanisms]. ( Kawecka-Jaszcz, K; Pośnik-Urbańska, A, 2006)
" Fibrosis of the right ventricle, the atria, and the pulmonary artery supports the concept that these effects are BP independent, corroborated by the finding that spironolactone in a dosage not sufficient to lower BP prevents myocardial fibrosis."2.42Aldosterone-induced cardiac damage: focus on blood pressure independent effects. ( Schmidt, BM; Schmieder, RE, 2003)
"Aldosterone has direct effects on the vasculature and has been associated with vascular smooth muscle cell hypertrophy, endothelial dysfunction, cardiac fibrosis, proteinuria, and renal vascular injury."2.42Aldosterone: a risk factor for vascular disease. ( Fritsch Neves, M; Schiffrin, EL, 2003)
"These forms of hypertension are rather rare in their complete expression, but they point to candidate genes whose mutations may predispose to hypertension."2.42[Monogenic hypertension]. ( Bähr, V; Diederich, S; Oelkers, W, 2003)
"Mineralocorticoid hypertension is the consequence of an overactivity of the epithelial sodium channel expressed at the apical membrane of renal cells in the distal nephron."2.42Forms of mineralocorticoid hypertension. ( Bonny, O; Ferrari, P, 2003)
"Primary hyperaldosteronism (PHA), autonomic secretion of aldosterone by the adrenal gland, is rare."2.42[Primary hyperaldosteronism]. ( Deinum, J; van den Meiracker, AH, 2003)
"Aldosterone is an important and independent target for therapeutic intervention in hypertension and hypertension-related diseases."2.42Aldosterone receptor antagonists for hypertension: what do they offer? ( Krum, H; Liew, D, 2003)
"The classical form of primary aldosteronism is a rare disease with prevalence rates of 0."2.42[The aldosterone to Renin ratio in secondary hypertension]. ( Reincke, M; Seiler, L, 2003)
"Hypertension is an important determinant of heart failure."2.42A neuroendocrine-immune interface. The immunostimulatory state of aldosteronism. ( Weber, KT, 2003)
"Obesity is a common problem in much of the western world today in that is linked directly with several disease processes, notably, hypertension."2.42Hypertension and obesity. ( Aneja, A; El-Atat, F; McFarlane, SI; Sowers, JR, 2004)
"Obesity has become an epidemic problem in western societies, contributing to metabolic diseases, hypertension and cardiovascular disease."2.42Mechanisms of obesity-related hypertension. ( Bornstein, SR; Ehrhart-Bornstein, M; Lamounier-Zepter, V, 2004)
" It is, therefore, not surprising that this analysis showed a small fall in blood pressure, and that a dose-response to salt reduction was not demonstrable."2.42Effect of longer-term modest salt reduction on blood pressure. ( He, FJ; MacGregor, GA, 2004)
"Aldosterone plays an important role in the pathogenesis of cardiovascular and renal disease that is independent of angiotensin II."2.42Pleiotropic actions of aldosterone and the effects of eplerenone, a selective mineralocorticoid receptor antagonist. ( Takeda, Y, 2004)
"Aldosterone has been only considered as a humoral factor playing a role in salt and water homeostasis and as a consequence controlling arterial blood pressure."2.41[Aldosterone and cardiovascular diseases, more than water and salt retention]. ( Duprez, D, 2002)
"Primary aldosteronism is a disorder characterized by hypertension and, in more severe form, hypokalemia, due to autonomous aldosterone secretion from the adrenocortical zona glomerulosa."2.41New genetic insights in familial hyperaldosteronism. ( Jackson, RV; Lafferty, A; Stratakis, C; Torpy, DJ, 2002)
"The two major subtypes of primary aldosteronism are unilateral aldosterone-producing adenoma (APA) and bilateral idiopathic hyperplasia (IHA)."2.41Primary aldosteronism: management issues. ( Young, WF, 2002)
"Hypertension is a major risk factor for progressive renal disease."2.41Aldosterone and the hypertensive kidney: its emerging role as a mediator of progressive renal dysfunction: a paradigm shift. ( Epstein, M, 2001)
"Aldosterone has been identified as a critically important neurohormone with direct detrimental effects on the myocardium."2.41Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure. ( Miller, AB; Srivastava, P, 2001)
"When primary aldosteronism is diagnosed, fewer than one-third of patients are suitable for surgery as initial treatment, but this still represents a significant percentage of hypertensive patients."2.41Primary aldosteronism: are we diagnosing and operating on too few patients? ( Gordon, RD; Rutherford, JC; Stowasser, M, 2001)
"Primary aldosterone excess or hyperaldosteronism is an important cause of hypertension which, when associated with an aldosterone secreting adenoma, is amenable to surgical cure."2.41Primary aldosteronism, a common entity? the myth persists. ( Padfield, PL, 2002)
"2."2.41Familial varieties of primary aldosteronism. ( Gordon, RD; Gunasekera, TG; Stowasser, M, 2001)
"The role of left ventricular hypertrophy as an independent risk factor for subsequent cardio-vascular events is well established, therefore the authors, in this brief review, describe the endocrine function of the heart and the role played by various factors, including hormones, in the development of cardiac remodeling during the course of hypertension."2.40[Pathophysiology of left ventricular hypertrophy in arterial hypertension]. ( Braconi-Quintaje, S; Lang, U; Vallotton, MB, 1997)
"The syndrome is due to a deficiency of the renal enzyme 11-beta-hydroxysteroid dehydrogenase type II, which protects the mineralocorticoid receptor against cortisol that binds to the mineralocorticoid receptor like aldosterone."2.40[Mineralocorticoid-induced hypertension]. ( Hensen, J; Oelkers, W, 1997)
"Among these, classic primary hyperaldosteronism and its glucocorticoid remediable variety, in which hypertension is secondary to aldosterone production, must be considered."2.40[Hypertension and mineralocorticoids. Usefulness of renin and aldosterone measurements]. ( Fardella, CE; Montero, J; Mosso, L, 1999)
"We report a rare case of primary hyperaldosteronism due to a unilateral adrenal cortical adenoma in an 11-year-old female patient."2.39Aldosterone-secreting adrenal cortical adenoma in an 11-year-old child and collective review of the literature. ( Chi, CS; Li, JT; Shu, SG, 1994)
"Glucocorticoid-remediable aldosteronism (GRA) is an autosomal-dominant form of human hypertension."2.39Glucocorticoid-remediable aldosteronism. ( Dluhy, RG; Lifton, RP, 1994)
"Hyperaldosteronism owing to aldosterone-producing adenoma (Conn syndrome) is a rare but potentially curable form of pediatric hypertension."2.39Conn syndrome in a child, caused by adrenal adenoma. ( Abasiyanik, A; Calişkan, U; Erkul, I; Kaymakçi, A; Oran, B; Yaşar, C, 1996)
"Enalapril maleate is a prodrug which when administered orally is hydrolysed to release the active converting enzyme inhibitor enalaprilat."2.37An overview of the clinical pharmacology of enalapril. ( Davies, RO; Gomez, HJ; Irvin, JD; Walker, JF, 1984)
"When used in congestive heart failure, ACE inhibitors exert a balanced vasodilator effect on arterial and venous beds and do not induce tachycardia or fluid retention."2.37Overview: the role of angiotensin-converting enzyme inhibitors in cardiovascular therapy. ( Abrams, WB; Davies, RO; Ferguson, RK, 1984)
"Aldosterone hypertension was a typical volume loading type with sodium retention, increased blood volume and extracellular fluid volume and a slow rise in arterial pressure."2.37Interaction between the natriuretic effects of renal perfusion pressure and the antinatriuretic effects of angiotensin and aldosterone in control of sodium excretion. ( Pan, YJ; Young, DB, 1984)
"In patients with congestive heart failure treated with digitalis, these natriuretic agents are particularly useful because of their potassium-sparing properties."2.37Clinical applications of antimineralocorticoids. ( Brunner, HR; Nüssberger, J; Waeber, B, 1988)
" Suitable techniques for the investigation of secondary aldosteronism of unknown cause and for primary and secondary hypoaldosteronism are described, as well as the adjustment of dosage for replacement therapy where mineralocorticoid secretion is deficient."2.37Disorders of mineralocorticoid activity. ( Drury, PL, 1985)
"Severe hypertension is more likely to occur in the predisposed, and malignant hypertension has been reported."2.35Drug-induced hypertension: pathogenesis and management. ( Stokes, GS, 1976)
"Usually hypertension is reversible after cessation of therapy with contraceptive steroids."2.35[Clinical aspects of hypertension under contraceptive steroids]. ( Kaulhausen, H; Klingsiek, L, 1976)
"Hypertension is common in patients with type 2 diabetes who carry increased cardiovascular risk; however, it is unknown how frequently they are tested for PA."1.91Screening for primary aldosteronism in the diabetic population: a cohort study. ( Libianto, R; Tan, SJ; Wong, J; Yang, J, 2023)
"Bilateral idiopathic hyperaldosteronism (IHA) is responsible for 60% of primary aldosteronism (PA) cases."1.91Unilateral Adrenalectomy for Primary Aldosteronism Due to Bilateral Adrenal Disease Can Result in Resolution of Hypokalemia and Amelioration of Hypertension. ( Bancos, I; Dy, BM; Foster, TR; Lyden, ML; McKenzie, TJ; Shariq, OA; Szabo Yamashita, T; Young, WF, 2023)
"According to the primary aldosteronism surgical outcome (PASO) criteria, complete and partial clinical success was achieved in 21 (40."1.91Catheter-based adrenal ablation: an alternative therapy for patients with aldosterone-producing adenoma. ( He, H; Jiang, J; Li, Q; Li, Y; Liu, X; Sun, F; Yan, Z; Zhang, H; Zhao, Z; Zhou, X; Zhu, Z, 2023)
"Primary aldosteronism (PA) patients have a higher degree of arterial stiffness, which can be reversed after adrenalectomy."1.91Implication of MR Activity in Posttreatment Arterial Stiffness Reversal in Patients With Primary Aldosteronism. ( Chang, CC; Chang, YY; Chen, ZW; Chiu, YW; Chueh, JS; Huang, WC; Hung, CS; Lee, BC; Liao, CW; Lin, YH; Lu, CC; Pan, CT; Tsai, CH; Wang, SM; Wu, VC, 2023)
"Primary Aldosteronism (PA) is increasingly considered as a common disease affecting up to 10% of the hypertensive population."1.91Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy. ( Bouhanick, B; Boulestreau, R; Costa, N; Cremer, A; Delchier, MC; Gombault-Datzenko, E; Gosse, P; Lagarde, S; Lepage, B; Molinier, L; Mounie, M; Papadopoulos, P; Rousseau, H; Trillaud, H, 2023)
"Primary aldosteronism (PA) screening relies on an elevated aldosterone to renin ratio with a minimum aldosterone level, which varies from 10 to 15 ng/dL (277-415."1.91Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening. ( Almeida, MQ; Bortolotto, LA; Brito, LP; Carnevale, FC; Cavalcante, ACBS; Chambo, JL; Coelho, FMA; Consolim-Colombo, FM; Drager, LF; Fagundes, GFC; Fragoso, MCBV; Freitas, TC; Goldbaum, TS; Latronico, AC; Ledesma, FL; Maciel, AAW; Mendonca, BB; Pereira, MAA; Petenuci, J; Pilan, B; Pio-Abreu, A; Silveira, JV; Srougi, V; Tanno, FY; Vilela, LAP; Zerbini, MCN, 2023)
"After genetic analysis, a diagnosis of Liddle syndrome was made due to the presence of a p."1.91A case report of a young boy with low renin and high aldosterone levels induced by Liddle syndrome who was previously misdiagnosed with primary aldosteronism. ( Jin, Y; Qiu, W; Yao, J, 2023)
"Primary hyperaldosteronism is a major cause of secondary hypertension and carries additional cardiovascular risks beyond that of the elevated blood pressure."1.91Fatty acids as a direct regulator of aldosterone hypersecretion. ( Albert, SG; Bruno, J; Dhindsa, S; Ling, G, 2023)
"Aldosterone has hypertrophic and profibrotic effects on the heart."1.91Serum aldosterone effect on left ventricular structure and diastolic function in essential hypertension. ( Al-Hashedi, EM; Juvenal, H; Mohammed, AA; Yu, J; Zhao, X, 2023)
"Aldosterone concentration was significantly higher in OC users than nonusers at 17 years (median 486 pmol/L vs 347 pmol/L, P < 0."1.91Effect of Oral Contraception on Screening Tests for Primary Aldosteronism: A 10-Year Longitudinal Study. ( Beilin, LJ; Fuller, PJ; Gwini, SM; Mori, TA; Schlaich, M; Stowasser, M; Yang, J; Young, MJ, 2023)
"Primary aldosteronism (PA) is the most common form of secondary hypertension, with its main manifestations including hypertension and hypokalemia."1.91Advances in Medical Treatment of Primary Aldosteronism. ( Ji, ZG; Li, YJ; Wen, J, 2023)
"The elevated aldosterone in primary aldosteronism (PA) is associated with increased insulin resistance and prevalence of diabetes mellitus (DM)."1.91Diabetes mellitus is associated with more adverse non-hemodynamic left ventricular remodeling and less recovery in patients with primary aldosteronism. ( Chang, CC; Chang, YR; Chang, YY; Chen, UL; Chueh, JS; Huang, KH; Hung, CS; Lai, TS; Lee, BC; Liao, CW; Lin, YH; Lu, CC; Tsai, CH; Wang, SM; Wu, VC, 2023)
"Primary aldosteronism (PA) was suspected because of the high plasma aldosterone concentration-to-plasma renin activity ratio."1.91Coexistence of Pheochromocytoma and Primary Aldosteronism due to Multiple Aldosterone-producing Micronodules in the Ipsilateral Adrenal Gland. ( Fujita, Y; Hino, M; Horikawa, O; Inoue, K; Kageyama, S; Kawauchi, A; Maegawa, H; Nakaizumi, N; Noujima, M; Sasano, H; Sato, D; Ugi, S; Wada, A; Yamazaki, Y; Yonishi, M, 2023)
"Primary aldosteronism (PA) is one of the most frequent causes of secondary hypertension."1.91International multicenter survey on screening and confirmatory testing in primary aldosteronism. ( Azizan, EABA; Beuschlein, F; Ceccato, F; Dalmazi, GD; Deinum, J; Furnica, RM; Gallego, NV; Gruber, S; Grytaas, MA; Kalugina, V; Kastelan, D; Katabami, T; Kobayashi, H; Kocjan, T; Kraljevic, I; Kürzinger, L; Lacroix, A; Laycock, K; Maiolino, G; Markou, A; Murakami, M; Naruse, M; Nijhoff, MF; O'Toole, S; Parasiliti-Caprino, M; Piaditis, G; Puar, T; Quinkler, M; Ragnarsson, O; St-Jean, M; Sukor, N; Suzuki, T; Tanabe, A; Tong, CV; Torre, EM; Tsuiki, M; Wada, N, 2023)
"Primary aldosteronism is the most frequent secondary hypertensive disease and is characterized by an elevated risk for cardiovascular disease."1.91Effect of the interaction between the visceral-to-subcutaneous fat ratio and aldosterone on cardiac function in patients with primary aldosteronism. ( Fujiwara, A; Haruna, A; Haze, T; Hirawa, N; Kawano, R; Kobayashi, Y; Ohki, Y; Ozawa, M; Saka, S; Suzuki, S; Tamura, K, 2023)
"Aldosterone was significantly associated with all-cause mortality (hazard ratio per standard deviation increase: 1."1.91Association of Aldosterone with Mortality in the General Population. ( Bidlingmaier, M; Heier, M; Herder, C; Koenig, W; Meisinger, C; Peters, A; Rathmann, W; Reincke, M; Roden, M; Seissler, J; Sujana, C; Then, C; Thorand, B, 2023)
"Primary aldosteronism (PA) is a common cause of secondary hypertension, whereas pheochromocytoma is a rare cause of it."1.91Pitfalls in the diagnosis and treatment of a hypertensive patient with unilateral primary aldosteronism and contralateral pheochromocytoma: a case report. ( Asayama, Y; Daa, T; Fujinami, H; Gotoh, K; Masaki, T; Miyamoto, S; Nishida, H; Okamoto, M; Ozeki, Y; Shibata, H; Shin, T; Yoshida, Y, 2023)
"Primary aldosteronism (PA), characterised by low-renin hypertension, confers a high cardiovascular risk and is the most common cause of secondary hypertension, with an increased prevalence in patients with treatment-resistant hypertension."1.91RAS-challenge as a first-look test for detection of primary aldosteronism in patients with treatment-resistant hypertension. ( Beger, C; Haller, H; Hinrichs, JB; Karg, T; Limbourg, FP; Meyer, BC; Ringe, B, 2023)
"RRBP1 deficiency in mice caused hyporeninemic hypoaldosteronism, resulting in lower blood pressure, severe hyperkalemia, and sudden cardiac death."1.91ER ribosomal-binding protein 1 regulates blood pressure and potassium homeostasis by modulating intracellular renin trafficking. ( Chang, YC; Chiu, CH; Chuang, GT; Chuang, LM; Fong, SW; Hee, SW; Hsieh, ML; Hsieh, PC; Hsu, CN; Hsuan, CF; Hung, YJ; Hwu, CM; Lee, HL; Li, WY; Lin, JW; Lin, SH; Lin, SW; Lin, WC; Wu, VC; Yang, WS, 2023)
"Women exposed to preeclampsia have a substantially increased risk of hypertension after pregnancy, but the mechanism remains unknown, leaving a missed interventional opportunity."1.91Smooth Muscle Mineralocorticoid Receptor Promotes Hypertension After Preeclampsia. ( Biwer, LA; Camarda, ND; Carvajal, BV; Ibarrola, J; Jaffe, IZ; Karumanchi, SA; Lu, Q; Man, JJ; Seely, EW; Skurnik, G; Stepanian, A; Zsengeller, Z, 2023)
"Hypertension plus obstructive sleep apnea (OSA) is recommended in some guidelines as an indication to screen for primary aldosteronism (PA), yet prior data has brought the validity of this recommendation into question."1.91Screening for Primary Aldosteronism Among Hypertensive Adults with Obstructive Sleep Apnea: A Retrospective Population-Based Study. ( Agharazii, M; Goupil, R; Hundemer, GL; Imsirovic, H; Kendzerska, T; Kline, GA; Knoll, G; Leung, AA; Madore, F; Sood, MM; Vaidya, A, 2023)
"Aldosterone was eventually isolated and identified in the fraction and was soon shown to cause hypertension when in excess."1.91An Abbreviated History of Aldosterone Metabolism, Current and Future Challenges. ( Gomez-Sanchez, CE; Gomez-Sanchez, EP, 2023)
"Primary aldosteronism (PA) is a typical example of low renin hypertension, whereas renal artery stenosis (RAS) is a classic form of high renin hypertension."1.91Renal Artery Stenosis Complicated with Primary Aldosteronism. ( Bao, M; Li, J, 2023)
"In aldosterone-treated rats compared with control rats, switching from a low-salt diet to a high-salt diet initiated significantly greater increases in mean arterial pressure and SVR and significantly greater decreases in heart rate and CO."1.91Hypertension in Primary Aldosteronism Is Initiated by Salt-Induced Increases in Vascular Resistance With Reductions in Cardiac Output. ( DiCarlo, SE; Kurtz, TW; Lujan, HL; Morris, RC; Pravenec, M, 2023)
"In this setting, primary aldosteronism (PA) is a frequent cause of RH and its prevalence in RH patients is likely higher than 20%."1.91Primary Aldosteronism and Drug Resistant Hypertension: A "Chicken-Egg" Story. ( Lenzini, L; Pintus, G; Rossi, GP; Rossitto, G; Seccia, TM, 2023)
"Primary hyperaldosteronism is the most common cause of secondary hypertension."1.91[Adrenalectomy for primary hyperaldosteronism : retrospective review of 57 patients in CHU of Liege]. ( Hamoir, E; Wilmont, E, 2023)
"Primary aldosteronism (PA) is considered the number one aetiology for secondary hypertension."1.91Duplicated adrenal veins in primary aldosteronism misdiagnosed with ectopic aldosteronoma due to apparent bilateral aldosterone suppression. ( Chen, K; Fan, C; Fang, T; Liu, H; Quan, H; Wei, W; Yu, J; Zhang, Y, 2023)
"Patients with primary aldosteronism (PA) have a higher risk of cardiovascular disease (CVD) than essential hypertension due to underlying hyperaldosteronism."1.91High plasma aldosterone concentration is associated with worse 24-h ambulatory blood pressure profile in patients with primary aldosteronism. ( Azushima, K; Haze, T; Kanaoka, T; Kinguchi, S; Kobayashi, K; Kobayashi, R; Morita, R; Sunohara, S; Tamura, K; Toya, Y; Wakui, H, 2023)
"Primary aldosteronism (PA) is the most common cause of endocrine hypertension."1.91Biochemical Evaluation by Confirmatory Tests after Unilateral Adrenalectomy for Primary Aldosteronism. ( Asari, Y; Daimon, M; Kageyama, K; Kinoshita, N; Murasawa, S; Nakada, Y; Takayasu, S; Usutani, M; Watanuki, Y, 2023)
"Data from the Taiwan Primary Aldosteronism Investigation Group database were analyzed, including patients with unilateral PA who had adrenalectomy between December 2015 and October 2018."1.91Association of urinary liver-type fatty acid-binding protein with outcomes after adrenalectomy for unilateral primary aldosteronism. ( Chen, CH; Chuang, YW; Lin, YH; Shiao, CC; Wu, CY; Wu, JT; Wu, MJ; Wu, VC; Yu, TM, 2023)
"Renal cysts were identified using contrast-enhanced computed tomography."1.91Non-suppression of renin by renal cysts in a subset of patients with primary aldosteronism-a prospective observational single center study. ( Hämäläinen, E; Hinkka, T; Huhtala, H; Matikainen, N; Nevalainen, PI; Nevalainen, R; Niemelä, O; Pörsti, I; Ylänen, A, 2023)
"Primary aldosteronism was diagnosed based on 4 h PAC, adrenal imaging and/or adrenal venous sampling (AVS)."1.91Using plasma aldosterone concentrations at 1 h of saline infusion test for the diagnosis of primary aldosteronism. ( Chanthanuwat, S; Jannoo, S; Phonanuwong, R; Soonthornpun, S, 2023)
"However, obesity has an independent deleterious impact on improvement in blood pressure post-adrenalectomy for PA."1.91The Impact of Obesity on the Resolution of Hypertension Following Adrenalectomy for Primary Hyperaldosteronism. ( Chidambaram, S; Damji, S; Di Marco, AN; Meeran, K; Palazzo, F; Todd, J; Van Den Heede, K; Wernig, F, 2023)
"Screening test results for primary aldosteronism were positive for about one-quarter of urban Indigenous and non-Indigenous participants."1.91Aldosterone and renin concentrations and blood pressure in young Indigenous and non-Indigenous adults in the Northern Territory: a cross-sectional study. ( Fuller, PJ; Gwini, SM; Ng, E; Singh, GR; Stowasser, M; Yang, J; Young, MJ, 2023)
"Primary aldosteronism (PA) is a well-known cause of secondary hypertension."1.91Simple standing test without furosemide is useful in the diagnosis of primary aldosteronism. ( Fushimi, Y; Iwamoto, H; Iwamoto, Y; Kaku, K; Kaneto, H; Katakura, Y; Kimura, T; Kusano, T; Mune, T; Nakanishi, S; Ohnishi, M; Sanada, J; Shimoda, M; Takenouchi, H; Tatsumi, F, 2023)
"Hypertension in CS promotes hypercortisolism-associated cardiovascular events."1.91Unique Gene Expression Signature in Periadrenal Adipose Tissue Identifies a High Blood Pressure Group in Patients With Cushing Syndrome. ( Caratti, G; Reincke, M; Stifel, U; Tuckermann, J; Vogel, F, 2023)
""Likely" primary aldosteronism was defined as ARR ≥ 70 pmol/mIU."1.91Associations Between Aldosterone-Renin-Ratio and Bone Parameters Derived from Peripheral Quantitative Computed Tomography and Impact Microindentation in Men. ( Anderson, KB; Diez-Perez, A; Gwini, SM; Henneberg, M; Holloway-Kew, KL; Hyde, NK; Kotowicz, MA; Liao, WH; Pasco, JA; Rufus-Membere, P; Sui, SX; Tembo, MC; Yang, J, 2023)
"Primary aldosteronism is the underlying cause of hypertension in primary care settings in approximately 6% of cases, and it is even more common in patients with resistant hypertension."1.91Primary Aldosteronism. ( Quencer, KB; Rugge, JB; Senashova, O, 2023)
"Primary aldosteronism (PA) with unilateral adrenal disease can be cured or improved by adrenalectomy."1.91Surgery based on computed tomography images might be feasible for primary aldosteronism patients with visible unilateral adenoma. ( Dai, J; Fang, C; He, W; Huang, X; Sun, F; Xu, J; Zhao, J, 2023)
"Newly presenting hypertension is much the same-hold off on first-order antihypertensive(s) and prescribe spironolactone 25 mg/day for 4 weeks."1.91Who and How Should We Screen for Primary Aldosteronism? ( Funder, JW, 2023)
"Aldosterone plays a key role in controlling blood pressure (BP) values by maintaining body salt, water, and fluid homeostasis."1.91Expression of functional mineralocorticoid receptor (MR) and G-protein coupled estrogen receptor (GPER) in human T lymphocytes. ( Caroccia, B; Carraro, S; Piazza, M; Rossi, GP, 2023)
"Patients with bilateral primary aldosteronism (PA) generally are treated with antihypertensive drugs, but optimal treatment for patients with complications due to refractory hypertension has not been established."1.91Unilateral adrenalectomy for a drug-resistant bilateral primary aldosteronism with heart failure: pathophysiology and surgical indication. ( Akaihata, H; Hata, J; Honda-Takinami, R; Hoshi, S; Kataoka, M; Kojima, Y; Matsuoka, K; Ogawa, S; Onagi, A; Sato, Y; Tanji, R, 2023)
"Atypical Liddle syndrome can be easily misdiagnosed due to its clinical phenotypes resembling hyperaldosteronism."1.91Liddle syndrome presenting with normal aldosterone levels: A case report. ( Pan, R; Wang, R; Zhang, R; Zhang, Y; Zhao, Y, 2023)
"The left adrenocortical adenoma was removed by robot-assisted laparoscopic resection."1.91Bilateral co-secretory lesions presenting with coexisting Cushing syndrome and primary aldosteronism: a case report. ( Chen, F; Chen, T; Gao, H; Li, L; Ren, Y; Tian, H, 2023)
"Aldosterone was associated inversely with urine sodium/creatinine (β: -0."1.72Correlation between kidney sodium and potassium handling and the renin-angiotensin-aldosterone system in children with hypertensive disorders. ( Perrin, EC; South, AM, 2022)
"Primary aldosteronism is a common, yet highly underdiagnosed, cause of hypertension that leads to disproportionately high rates of cardiovascular disease."1.72Screening Rates for Primary Aldosteronism Among Individuals With Hypertension Plus Hypokalemia: A Population-Based Retrospective Cohort Study. ( Agharazii, M; Goupil, R; Hundemer, GL; Imsirovic, H; Knoll, G; Madore, F; Sood, MM; Vaidya, A; Yozamp, N, 2022)
"In 2017, the Primary Aldosteronism Surgical Outcome (PASO) investigators proposed consensus criteria for clinical and biochemical outcomes."1.72Prediction of long-term biochemical cure in patients with unilateral primary hyperaldosteronism treated surgically based on the early post-operative plasma aldosterone value. ( Ishihara, Y; Kaneko, H; Kusakabe, T; Nanba, K; Satoh-Asahara, N; Tagami, T; Tsuiki, M; Umakoshi, H; Yasoda, A, 2022)
" The results of restricted cubic splines showed the dose-response association between increasing PAC, ARR, decreasing serum potassium, and the risk of WMLs."1.72Plasma aldosterone concentration is associated with white matter lesions in patients with primary aldosteronism. ( Heizhati, M; Li, N; Liu, Y; Luo, Q; Wang, M; Yao, X; Yuan, Y; Zhu, Q, 2022)
"Only 795 (4."1.72Screening Rate for Primary Aldosteronism Among Patients With Apparent Treatment-Resistant Hypertension: Retrospective Analysis of Current Practice. ( Tessier, KM; Zekarias, K, 2022)
"Primary aldosteronism (PA) is the commonest cause of endocrine hypertension ranging from 4."1.72Enhanced performance of a modified diagnostic test of primary aldosteronism in patients with adrenal adenomas. ( Chrousos, GP; Gravvanis, C; Kaltsas, GA; Kanti, G; Markou, A; Papanastasiou, L; Piaditis, G; Voulgaris, N; Zografos, GN, 2022)
"We identified patients with aortic dissection and aneurysm with assessed PAC before disease onset from hospital-based electronic database and set as case group."1.72Higher Plasma Aldosterone Concentrations Are Associated With Elevated Risk of Aortic Dissection and Aneurysm: a Case-Control Study. ( Gan, L; Heizhati, M; Hong, J; Li, N; Lin, M; Luo, Q; Wang, M; Yao, X; Yue, N; Zhang, W; Zhu, Q, 2022)
"Spironolactone was initiated."1.72Apparent mineralocorticoid excess: A diagnosis beyond classical causes of severe hypertension in a child. ( Baltu, D; Çelik Ertaş, NB; Duzova, A; Gönç, N; Gulhan, B; Ozcan, HN; Özdemir, G; Ünsal, Y; Utine, E, 2022)
"Primary aldosteronism represents the most frequent cause of endocrine hypertension."1.72[Diagnosis and therapy of primary aldosteronism: new aspects]. ( Asbach, E; Reincke, M, 2022)
"Diagnosis of primary hyperaldosteronism in pregnancy is complicated due to lack of reference ranges for aldosterone, renin and aldosterone-to-renin ratio."1.72Establishing Reference Ranges for Aldosterone, Renin and Aldosterone-to-Renin Ratio for Women in the Third-Trimester of Pregnancy. ( Grzesiak, M; Horzelski, W; Lewandowski, KC; Lewinski, A; Tadros-Zins, M, 2022)
"Primary aldosteronism (PA) is the most common and potentially curable endocrine cause of secondary hypertension, and carries a worse prognosis than essential hypertension."1.72Screening for primary aldosteronism is underutilised in patients with chronic kidney disease. ( Chauhan, K; Fuller, PJ; Hutton, H; Kerr, PG; Libianto, R; Ryan, J; Schachna, E; Wilson, S; Yang, J, 2022)
"To assess the identification of primary aldosteronism (PA) in newly diagnosed, treatment-naïve patients with hypertension by screening in primary care."1.72Detecting primary aldosteronism in Australian primary care: a prospective study. ( Fuller, PJ; Gwini, SM; Libianto, R; Nuttall, P; Russell, GM; Shen, J; Stowasser, M; Yang, J; Young, MJ, 2022)
"Unilateral subtype of primary aldosteronism (PA) is a common surgically curable form of endocrine hypertension."1.72Machine learning-based models for predicting clinical outcomes after surgery in unilateral primary aldosteronism. ( Fukumoto, T; Ichijo, T; Ishihara, Y; Iwahashi, N; Kaneko, H; Katsuhara, S; Matsuda, Y; Ogata, M; Ogawa, Y; Sakamoto, R; Sakamoto, S; Tagami, T; Terada, E; Umakoshi, H; Wada, N; Watanabe, T; Yokomoto-Umakoshi, M, 2022)
"Among 43 patients with primary aldosteronism (PA), thirteen APA patients were enrolled in this study."1.72Early Renin Recovery After Adrenalectomy in Aldosterone-Producing Adenomas: A Prospective Study. ( Antonini, SR; de Castro, M; Elias, J; Elias, PCL; Mermejo, LM; Molina, CAF; Moreira, AC; Muglia, VF; Tucci, S, 2022)
"Primary aldosteronism (PA) is associated with higher cardiovascular morbidity and mortality rates than essential hypertension."1.72Japan Endocrine Society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021. ( Hasegawa, T; Hashimoto, S; Haze, T; Ichijo, T; Izawa, S; Katabami, T; Kobayashi, H; Kurihara, I; Naruse, M; Ogawa, Y; Ohno, Y; Oki, Y; Omura, M; Otsuki, M; Rakugi, H; Saiki, A; Sakamoto, R; Satoh, F; Shibata, H; Sone, M; Takahashi, K; Takeda, Y; Tamura, K; Tanabe, A; Tanaka, T; Tsuiki, M; Wada, N; Yamamoto, K; Yoneda, T; Yoshimoto, T, 2022)
"Aldosterone (ALD) is a steroid hormone secreted by the zona glomerulosa of the adrenal cortex that mainly acts on the kidney to regulate sodium ion and water reabsorption."1.72Creation of a quick and sensitive fluorescent immunosensor for detecting the mineralocorticoid steroid hormone aldosterone. ( Dong, H; Dong, J; Gomez-Sanchez, CE; Inagaki, T; Jiang, G; Liang, J; Ueda, H; Wang, H; Yi, Z, 2022)
"Primary aldosteronism (PA) is the most common cause of secondary hypertension, and patients are at an increased risk of atrial fibrillation (AF) and stroke."1.72Primary Aldosteronism More Prevalent in Patients With Cardioembolic Stroke and Atrial Fibrillation. ( Aw, TC; Chai, SC; Fones, S; Foo, RSY; Lai, J; Mamauag, MJB; Nguyen, V; Ong, L; Puar, TH; Saffari, SE; Tu, TM; Zhang, M, 2022)
"Primary aldosteronism (PA) and nonclassic apparent mineralocorticoid excess (NCAME) have been recognized as endocrine-related conditions having a broad clinical-biochemical spectrum, spanning from normotension to severe arterial hypertension (AHT)."1.72Clinical, biochemical, and miRNA profile of subjects with positive screening of primary aldosteronism and nonclassic apparent mineralocorticoid excess. ( Carvajal, CA; Fardella, CE; Pérez, JA; Tapia-Castillo, A, 2022)
"Patients were screened for primary aldosteronism with the aldosterone-renin ratio and underwent a saline infusion test for diagnostic confirmation."1.72Prevalence and clinical characteristics of primary aldosteronism in a tertiary-care center in Korea. ( Ha, J; Hong, N; Ku, CR; Lee, CJ; Park, S; Rhee, Y; Yoon, M, 2022)
"Among those Liddle syndrome patients confirmed by a genetic test, for Test kit A all ARR were screened positive while for test kit B negative."1.72Liddle syndrome misdiagnosed as primary aldosteronism is caused by inaccurate aldosterone-rennin detection while a novel ( Chen, L; Qu, D; Sun, Q; Wu, C; Xu, X; Yang, Y; Zhao, X, 2022)
"Ambulatory FST is safe and accurate and can be performed with significantly less healthcare costs compared to FSTin."1.72Ambulatory fludrocortisone suppression test in the diagnosis of primary aldosteronism: Safety, accuracy and cost-effectiveness. ( Avander, K; Calissendorff, J; Carasel, A; Falhammar, H; Shabo, I; Volpe, C, 2022)
"Background Primary aldosteronism can cause cardiac dysfunction, including left ventricular hypertrophy, left ventricular diastolic dysfunction, and left atrial enlargement."1.72Comparison of Echocardiographic Changes Between Surgery and Medication Treatment in Patients With Primary Aldosteronism. ( Hoshino, Y; Inoue, K; Nakai, K; Nishikawa, T; Ono, M; Osada, J; Saito, J; Tsurutani, Y; Ueda, T; Yumoto, K, 2022)
"The aldosterone/renin ratio was proposed to increase the detection rate of PA, which has the shortcoming of a high underdiagnosis rate when relying only on clinical manifestations."1.72Reliability Analysis of a Functional Diagnostic Test for Primary Hyperaldosteronism Based on Data Analysis. ( Cai, J; Wang, Y, 2022)
"Background Primary aldosteronism (PA) is a common but under-recognized cause of secondary hypertension."1.72Primary Aldosteronism Screening Rates Differ with Sex, Race, and Comorbidities. ( Grigoryan, S; Holevinski, L; Liu, H; Nhan, W; Turcu, AF; Urban, C; Zhang, L; Zhao, L, 2022)
"Racial differences in obstructive sleep apnea (OSA) and increased aldosterone level may explain the racial disparity in resistant hypertension prevalence."1.72Relationship Between Risks for Obstructive Sleep Apnea, Resistant Hypertension, and Aldosterone Among African American Adults in the Jackson Heart Study. ( Eaton, CB; Gjelsvik, A; Hall, ME; Koo, P; McCool, FD; Muntner, P, 2022)
"Primary aldosteronism (PA) is the most common cause of secondary hypertension."1.72Clinical and biochemical predictors and predictive model of primary aldosteronism. ( Atthakomol, P; Manosroi, W; Tacharearnmuang, N, 2022)
"Hypertension was induced in the rats by adding 8% NaCl in their diet for six weeks."1.72Anti-Hypertensive Effects of Anthocyanins from Hibiscus sabdarifa Calyx on the Renin-Angiotensin-Aldoslestrone System in Wistar Rats. ( Madueke, P; Nwachukwu, D; Okorie, P; Ubom, R; Ugwu, P, 2022)
"Primary aldosteronism (PA), including aldosterone and cortisol producing adenoma (A/CPA), is the most common trigger of secondary hypertension."1.72Two cases of aldosterone and cortisol producing adenoma with different histopathological features: A case report. ( Gao, H; Li, L; Tian, H, 2022)
"Primary aldosteronism (PA) represents the most frequent cause of endocrine arterial hypertension."1.72Prevalence of Primary Aldosteronism in Newly Diagnosed Hypertensive Patients in Primary Care. ( Asbach, E; Bekeran, M; Bidlingmaier, M; Kellnar, A; Reincke, M; Schelling, J, 2022)
"Primary aldosteronism is the most common surgically curable cause of endocrine hypertension."1.72Impact of dedicated multidisciplinary service on patient selection and outcomes for surgical treatment of primary aldosteronism. ( Fuller, PJ; Grodski, S; Lee, JC; Libianto, R; Shen, J; Yang, J; Zhang, J, 2022)
"Primary aldosteronism is now recognized as the most common cause of secondary hypertension."1.72Primary aldosteronism presenting as embolic myocardial infarction. ( Jin, HY; Kim, YJ; Lee, HW; Lee, KA, 2022)
"Hypertension is a major health problem common in the elderly people."1.72Green tea could improve elderly hypertension by modulating arterial stiffness, the activity of the renin/angiotensin/aldosterone axis, and the sodium-potassium pumps in old male rats. ( Akbari, A; Gao, J; Wang, T, 2022)
"Preeclampsia is a life-threatening disorder of pregnancy unique to humans."1.72Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia. ( Dimitriadis, E; Menkhorst, E; Santos, L; St-Pierre, Y; Young, MJ; Zhang, JG; Zhou, W, 2022)
"Aldosterone was given for the last 4 months."1.72Effect of Metabolic Adaptation by Voluntary Running Wheel Activity and Aldosterone Inhibition on Renal Function in Female Spontaneously Hypertensive Rats. ( Atmanspacher, F; Grgic, I; Schlüter, KD; Schreckenberg, R; Wolf, A, 2022)
"Primary aldosteronism, eponymously known as Conn's syndrome, has recently gained recognition as the most common cause of endocrine hypertension."1.62The role of surgery in Conn's syndrome - a case of refractory hypertension secondary to an aldosterone secreting adenoma. ( Bombil, I; Carides, MD; Christofides, C; Sishuba, NT, 2021)
"Primary aldosteronism was diagnosed."1.62Hypertension with unilateral adrenal aldosterone and cortisol cosecreting adenoma: A case report. ( Chen, X; Chu, SL; Hu, Z; Luo, FX; Shao, Y; Wang, JG, 2021)
"The Taiwan Society of Aldosteronism (TSA) Task Force reviewed the latest literature and reached a consensus after group meetings."1.62Taiwan mini-frontier of primary aldosteronism: Updating detection and diagnosis. ( Chang, CC; Chen, CK; Chen, YY; Er, LK; Lai, TS; Lu, CC; Tu, KH; Wu, VC; Zeng, YH, 2021)
"Primary aldosteronism is an underdiagnosed cause of hypertension."1.62Intraindividual Variability of Aldosterone Concentrations in Primary Aldosteronism: Implications for Case Detection. ( Fudim, T; Hundemer, GL; Moussa, M; Sacks, B; Underhill, J; Vaidya, A; Yozamp, N, 2021)
"Primary aldosteronism was screened by measuring plasma aldosterone concentration (PAC) and direct renin concentration (DRC) and calculating aldosterone-to-renin ratio (ARR), followed by confirmatory saline infusion test (SIT) according to Endocrine Society Guideline."1.62High prevalence and a long delay in the diagnosis of primary aldosteronism among patients with young-onset hypertension. ( Alam, S; Goyal, A; Kandasamy, D; Karthikeyan, G; Khadgawat, R; Singh, S; Vishnubhatla, S, 2021)
" In patients who have bilateral aldosterone hypersecretion, the optimal management is a low sodium diet and lifelong treatment with a mineralocorticoid receptor antagonist administered at a dosage to maintain a high-normal serum potassium concentration without the aid of oral potassium supplements."1.62[Primary aldosteronism: from diagnosis to therapy in clinical practice]. ( Cassaniti, L; Francese, GM; Gulizia, MM; Vetri, M, 2021)
"Objective Primary aldosteronism (PA) is a major cause of secondary hypertension."1.62Primary Aldosteronism with Parathyroid Hormone Elevation: A Single-center Retrospective Study. ( Aono, D; Fujimoto, A; Gondoh-Noda, Y; Higashitani, T; Karashima, S; Kometani, M; Matsuoka, T; Sawada, K; Takeda, Y; Usukura, M; Yoneda, T; Yoshikura, S, 2021)
"BACKGROUND Primary aldosteronism, also known as Conn's syndrome, is a clinical condition caused by excessive production of aldosterone."1.62Hypokalemia-Induced Rhabdomyolysis Caused by Adrenal Tumor-Related Primary Aldosteronism: A Report of 2 Cases. ( Chen, CT; Lin, CM; Wang, YC, 2021)
"Her high blood pressure was initially attributed to emotional stress, however, she was later referred for additional evaluation for secondary causes of hypertension."1.62[HYPERTENSION IN A YOUNG WOMAN WITH ANXIETY DISORDER: THE CHICKEN OR THE EGG?] ( Angel Korman, A; Hausmann, M; Katzir, Z; Rapoport, V; Raz, O, 2021)
"Patients with primary aldosteronism (PA) have cardiac remodeling due to hemodynamic and non-hemodynamic causes."1.62Hemodynamic and Non-Hemodynamic Components of Cardiac Remodeling in Primary Aldosteronism. ( Chang, CC; Chang, YR; Chang, YY; Chen, YL; Chen, ZW; Hung, CS; Lee, BC; Liao, CW; Lin, LC; Lin, YH; Pan, CT; Tsai, CH; Wu, XM, 2021)
"Allisartan isoproxil (ALL) is a new angiotensin II receptor blocker and a new antihypertensive drug discovered and developed in China."1.62Allisartan isoproxil reduces mortality of stroke-prone rats and protects against cerebrovascular, cardiac, and aortic damage. ( Cheng, MH; Fu, FH; Ling, QS; Liu, AJ; Liu, JG; Miao, CY; Tian, JS; Zhang, SL, 2021)
"Primary aldosteronism (PA) is highly prevalent in hypertensive population."1.62Determination of adrenal hypersecretion in primary Aldosteronism without aldosterone-production adenomas. ( He, H; Hong, Y; Liu, X; Sun, F; Yan, Z; Zhang, H; Zhao, Z; Zhu, Z, 2021)
"Residual hypertension was defined as persistent hypertension > 140/90 mmHg or requiring anti-hypertensive medications 1 year after surgery."1.62Comparison of cystatin C-based and creatinine-based glomerular filtration rate in the prediction of postoperative residual hypertension in aldosterone-producing adenoma patients after adrenalectomy. ( Chang, CC; Chen, CW; Chiu, YW; Hung, CS; Liao, SC; Lin, YH; Liu, KL; Tsai, CH; Tsai, IJ; Wu, VC, 2021)
"Primary aldosteronism has two main clinically and biologically distinct subtypes: unilateral aldosterone-producing adenoma (APA) and bilateral adrenal hyperplasia (BAH)."1.62Subtype-specific trends in the clinical picture of primary aldosteronism over a 13-year period. ( Fujii, Y; Ichijo, T; Inagaki, N; Itoh, H; Kamemura, K; Katabami, T; Kawashima, J; Kobayashi, H; Kurihara, I; Naruse, M; Ogawa, Y; Oki, K; Saito, K; Sone, M; Suzuki, T; Tamura, K; Tanabe, A; Tsuiki, M; Wada, N; Yamada, M; Yamada, T; Yamamoto, K; Yasoda, A; Yoneda, T, 2021)
"Essential hypertension is a pivotal risk factor for the development of cardiovascular disease (CVD)."1.62Aldosterone hyperreactivity to acute psychosocial stress induction in men with essential hypertension. ( Ehlert, U; Gideon, A; Sauter, C; von Känel, R; Wirtz, PH, 2021)
"Primary aldosteronism (PA) is the most common endocrine cause of arterial hypertension."1.62Prevalence of Primary Aldosteronism Across the Stages of Hypertension Based on a New Combined Overnight Test. ( Chrousos, G; Gravvanis, C; Gryparis, A; Kaltsas, G; Kapsali, C; Kassi, E; Kyriazi, E; Markou, A; Papanastasiou, L; Piaditis, G; Tyfoxylou, E; Vlachou, S; Voulgaris, N, 2021)
"Primary aldosteronism (PA), as a cause of secondary hypertension, can cause more serious cardiovascular damage than essential hypertension."1.62A case of primary aldosteronism with a negative aldosterone-to-renin ratio. ( Ding, Y; Liu, F; Wang, L, 2021)
"Primary aldosteronism (PA) is a common curable cause of hypertension."1.56Historical changes and between-facility differences in adrenal venous sampling for primary aldosteronism in Japan. ( Fujii, Y; Fujita, M; Ichijo, T; Inagaki, N; Itoh, H; Kamemura, K; Katabami, T; Kawashima, J; Kobayashi, H; Kurihara, I; Matsuda, Y; Miyauchi, S; Naruse, M; Ogasawara, T; Ogawa, Y; Ogo, A; Okamura, S; Otsuki, M; Shibata, H; Shibayama, Y; Sone, M; Suzuki, T; Takahashi, K; Takeda, Y; Tsuiki, M; Umakoshi, H; Wada, N; Watanabe, M; Yamamto, K; Yanase, T; Yoshimoto, T, 2020)
"Primary aldosteronism is a common cause of secondary hypertension."1.56Adherence to consensus guidelines for screening of primary aldosteronism in an urban healthcare system. ( Beninato, T; Fahey, TJ; Sivarajah, M, 2020)
"Primary aldosteronism (PA) is the most frequent cause of secondary hypertension."1.56Construction of a predictive scoring system as a guide to screening and confirmation of the diagnosis of primary aldosteronism. ( Kietsiriroje, N; Murray, RD; Suntornlohanakul, O; Wonghirundecha, R, 2020)
"Primary aldosteronism (PA) is known to increase vertebral fracture (VF), although the detailed mechanism remains to be elucidated."1.56Unilateral primary aldosteronism as an independent risk factor for vertebral fracture. ( Fukumoto, T; Matsuda, Y; Nagata, H; Ogata, M; Ogawa, Y; Sakamoto, R; Umakoshi, H; Yokomoto-Umakoshi, M, 2020)
"Essential hypertension is a prevalence chronic cardiovascular disease, which is treated by traditional Chinese medicine (TCM) in China."1.56Pharmacodynamics and metabonomics study of Tianma Gouteng Decoction for treatment of spontaneously hypertensive rats with liver-yang hyperactivity syndrome. ( Cong, H; Dong, H; Du, W; Zhang, L; Zhang, S, 2020)
"Primary aldosteronism (PA) contributed to the cardiovascular disease and metabolic alterations independent of the blood pressure level."1.56The effect of vitamin D treatment on clinical and biochemical outcomes of primary aldosteronism. ( Azhar Shah, S; Ismail, NA; Kamaruddin, NA; Sukor, N, 2020)
"Hyperaldosteronism has been reported to be associated with a higher prevalence of non-alcoholic fatty liver disease (NAFLD)."1.56The risk factors for hepatic steatosis in patients with primary aldosteronism. ( Atsumi, T; Baba, S; Nakamura, A; Obara, S; Sakai, H; Shibayama, Y; Terae, S; Usubuchi, H; Wada, N, 2020)
"Primary aldosteronism (PA) is notably an independent risk factor for cerebral vascular disease but currently with limited knowledge among young adults."1.56Primary aldosteronism in young adults with acute stroke: Prevalence and clinical characteristics. ( Chen, H; Cheng, Q; Du, Z; He, W; Hu, J; Li, Q; Luo, T; Ma, L; Mei, M; Song, Y; Tang, Z; Wang, Z; Yang, S, 2020)
"Treatment with aliskiren decreased urinary aldosterone excretion at 4 weeks and increased it at 12 weeks."1.56Impact of mineralocorticoid receptor blockade with direct renin inhibition in angiotensin II-dependent hypertensive mice. ( Aono, D; Demura, M; Hashimoto, A; Higashitani, T; Karashima, S; Kometani, M; Konishi, S; Takeda, Y; Yoneda, T, 2020)
"Primary aldosteronism is a nonsuppressible renin-independent aldosterone production that causes hypertension and cardiovascular disease."1.56The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study. ( Brown, JM; Calhoun, DA; Carey, RM; Hopkins, PN; Siddiqui, M; Vaidya, A; Williams, GH, 2020)
"Hypertension was the most common chief complaint, in contrast, the proportion of fatigue and/or numbness as the symptoms of hypokalemia was declining."1.56[Diagnosis and Treatment of Primary Aldosteronism in West China Hospital of Sichuan University from 2009 to 2018]. ( Chen, T; Li, QR; Li, YM; Liu, HD; Ren, Y; Tian, HM; Wang, W; Zhu, YC, 2020)
"Conn's syndrome is a curable condition if identified properly."1.56Seizure and coma secondary to Conn's syndrome: a case report. ( Alseddeeqi, E; Altinoz, A; Ghashir, NB, 2020)
"Primary aldosteronism (PA) occurs in 10%-20% of patients with resistant hypertension."1.56Evaluation of Adrenal Vein Sampling Use and Outcomes in Patients With Primary Aldosteronism. ( Bloomgarden, N; Friedmann, P; In, H; Laird, AM; Libutti, SK; McAuliffe, JC; Yeung, A, 2020)
" Catheter-based adrenal ablation appears to produce substantial and sustained blood pressure reduction and biochemical improvement, with only minor adverse events in PA patients without apparent aldosteronoma."1.56Adrenal artery ablation for primary aldosteronism without apparent aldosteronoma: An efficacy and safety, proof-of-principle trial. ( Bu, X; He, H; Hong, Y; Li, Q; Li, Y; Liu, X; Shen, R; Sun, F; Yan, Z; Yang, G; Zhang, H; Zhao, Z; Zheng, H; Zhou, X; Zhu, Z, 2020)
"The diagnostic algorithm for primary aldosteronism is sequentially based on hormonal tests (screening and confirmation tests), followed by lateralization studies (adrenal CT scanning and adrenal venous sampling) to distinguish between unilateral and bilateral disease."1.56Genetics, prevalence, screening and confirmation of primary aldosteronism: a position statement and consensus of the Working Group on Endocrine Hypertension of The European Society of Hypertension. ( Amar, L; Beuschlein, F; Deinum, J; Fallo, F; Lin, YH; Monticone, S; Morganti, A; Mulatero, P; Nishikawa, T; Prejbisz, A; Rossi, GP; Seccia, TM; Widimsky, J; Zennaro, MC, 2020)
" In patients with bilateral aldosterone hypersecretion, the optimal is a low-sodium diet and lifelong treatment with a mineralocorticoid receptor antagonist administered at a dosage to reach a high-normal serum potassium concentration."1.56[Primary aldosteronism: The Mayo Clinic approach]. ( Balutina, OV; Beltsevich, DG; Ladygina, DO; Young, W, 2020)
"Hypertension is a common clinical problem, and increased aldosterone is the most prevalent underlying characteristic."1.56Body mass index predicts aldosterone production in hypertensive postmenopausal women. ( Geng, X; Hou, X; Li, L; Xu, Y, 2020)
"Aldosterone is a key factor in adverse cardiovascular remodeling by acting on the mineralocorticoid receptor (MR) in different cell types."1.51Endothelial cell mineralocorticoid receptors oppose VEGF-induced gene expression and angiogenesis. ( Bode, C; Deng, L; Esser, JS; Fürst, D; Hein, L; Huck, M; Kowalski, J; Lother, A; Moser, M, 2019)
"Primary aldosteronism (PA) may cause myocardial injury."1.51Speckle-Tracking Echocardiographic Layer-Specific Strain Analysis on Subclinical Left Ventricular Dysfunction in Patients With Primary Aldosteronism. ( Chen, X; Chen, Y; Li, Y; Shao, S; Wang, D; Wang, JG; Xu, JZ; Xu, TY; Zhang, W; Zhu, LM, 2019)
"Aldosterone/renin ratio was available in 1473 patients, and abnormal in 374 (25."1.51Rates of abnormal aldosterone/renin ratio in African-origin compared to European-origin patients: A retrospective study. ( Abadi, S; Ahmed, KS; Behan, LA; Bogdanet, D; Boran, G; Dineen, R; Gibney, J; Sherlock, M; Woods, CP, 2019)
"To determine the frequency of primary hyperaldosteronism in young hypertensives in hospital settings of Rawalpindi."1.51Frequency of Primary Hyperaldosteronism in Young Hypertensives in a Tertiary Care Setting of Rawalpindi. ( Akram, A; Asif, N; Gilani, M; Nawaz, A, 2019)
"Primary aldosteronism (PA) is a frequent cause of resistant hypertension."1.51[Two case reports on resistant hypertension]. ( Beger, C; Haller, H; Limbourg, FP, 2019)
"Aldosterone has been linked with obesity, metabolic syndrome (MetS), pro-inflammatory, and prothrombotic states; however, most studies relate these indicators with primary aldosteronism (PA), excluding non-PA patients."1.51The Aldosterone/Renin Ratio Predicts Cardiometabolic Disorders in Subjects Without Classic Primary Aldosteronism. ( Allende, F; Barros, ER; Baudrand, R; Campino, C; Carvajal, C; Fardella, CE; Fuentes, CA; García, H; Kalergis, AM; Martínez-Aguayo, A; Olmos, R; Solari, S; Tapia-Castillo, A; Vecchiola, A, 2019)
"The diagnostic workup for primary aldosteronism includes a screening step using the aldosterone-to-renin ratio (ARR) and a confirmatory step based on dynamic testing of aldosterone secretion autonomy."1.51Evaluation of Biochemical Conditions Allowing Bypass of Confirmatory Testing in The Workup of Primary Aldosteronism: A Retrospective Study in a French Hypertensive Population. ( Deberles, E; Guenet, D; Haddouche, A; Morello, R; Reznik, Y; Vivien, M, 2019)
"Patients with primary aldosteronism induced hypertension are more likely to experience cardiovascular events compared to patients with essential hypertension."1.51Hypertension with primary aldosteronism is associated with increased carotid intima-media thickness and endothelial dysfunction. ( Demirkiran, A; Dreijerink, KM; Elitok, A; Everaars, H; Ozcan, M; Smulders, YM; Tanakol, R; van de Ven, PM, 2019)
"Primary aldosteronism (PA) is the most frequent cause of secondary hypertension."1.51Sex Difference in the Association Between Subtype Distribution and Age at Diagnosis in Patients With Primary Aldosteronism. ( Akasaka, H; Chiba, Y; Fujita, M; Ichijo, T; Izawa, S; Kamemura, K; Katabami, T; Kawashima, J; Kobayashi, H; Kurihara, I; Matsuda, Y; Miyauchi, S; Nagasawa, M; Nakamaru, R; Naruse, M; Ogawa, Y; Okamura, S; Rakugi, H; Sone, M; Takeda, Y; Tamura, K; Tanabe, A; Tsuiki, M; Wada, N; Watanabe, M; Yamamoto, K; Yoshimoto, T, 2019)
"The diagnosis of primary hyperaldosteronism (PHPA) has progressively increased over the last years and some authors consider it as the main cause of secondary hypertension."1.51[Primary hyperaldosteronism in a population of hypertensive patients]. ( Artiles Vizcaíno, J; Lorenzo Villalba, N; Marrero Medina, I; Rivera Martínez, E; Sablón González, N; Suárez Ortega, S, 2019)
"Primary aldosteronism (PA) is hemodynamically independently associated with arterial wall stiffness as assessed by pulse wave velocity (PWV) compared with essential hypertension."1.51Aldosterone Induces Vascular Damage. ( Chang, CC; Chen, CH; Chen, ZW; Cheng, HM; Hung, CS; Liao, CW; Lin, YH; Pan, CT; Sung, SH; Wu, VC, 2019)
"The diagnostic criteria of primary aldosteronism were plasma aldosterone concentration-to-plasma renin activity ratio [ARR, (ng/dl)/(ng/ml per h)] at least 20 and at least one positive result in four types of challenge tests."1.48Screening of primary aldosteronism by clinical features and daily laboratory tests: combination of urine pH, sex, and serum K. ( Ando, T; Endo, T; Fukuhara, S; Fukuma, S; Hasegawa, T; Koyama, M; Mita, T; Miura, T; Moniwa, N; Ohno, K; Ohnuma, Y; Shimizu, S; Takada, A; Tobisawa, T; Togashi, N; Tsuchida, A; Yamashita, T; Yoshida, H, 2018)
"The aldosterone-treated mice were exposed to NaCl drinking water (1%) during the hormone administration."1.48Disruption of the with no lysine kinase-STE20-proline alanine-rich kinase pathway reduces the hypertension induced by angiotensin II. ( Alessi, DR; Bobadilla, NA; Castaneda-Bueno, M; Cervantes-Perez, LG; Gamba, G; Jimenez, JV; Rojas-Vega, L; Vazquez, N, 2018)
"Primary aldosteronism is associated with a higher incidence of left ventricular (LV) hypertrophy and diastolic dysfunction than essential hypertension."1.48Aldosterone induces left ventricular subclinical systolic dysfunction: a strain imaging study. ( Chang, YY; Chen, CW; Chen, ZW; Huang, KC; Hung, CS; Lee, JK; Liao, CW; Lin, LC; Lin, YH; Wu, VC, 2018)
"In patients with KCNJ5-mutated APA, left ventricular hypertrophy was significantly decreased by surgical treatment in patients from either Cured or Improved groups, although those patients with wild-type KCNJ5 showed no change."1.48KCNJ5 mutation as a predictor for resolution of hypertension after surgical treatment of aldosterone-producing adenoma. ( Kitamoto, T; Nishikawa, T; Omura, M; Saito, J; Suematsu, S, 2018)
"The Primary Aldosteronism Surgical Outcomes (PASO) group recently established new consensus definitions for biochemical and clinical cure of PA."1.48Refining the Definitions of Biochemical and Clinical Cure for Primary Aldosteronism Using the Primary Aldosteronism Surgical Outcome (PASO) Classification System. ( Auchus, RJ; Cohen, MS; Gauger, PG; Hughes, DT; Miller, BS; Nanba, AT; Turcu, AF, 2018)
"Microalbuminuria was determined from 24-hour urine collections."1.48Aldosterone as a mediator of microvascular and macrovascular damage in a population of normotensive to early-stage hypertensive individuals. ( Anyfanti, P; Douma, S; Gavriilaki, E; Gkaliagkousi, E; Lazaridis, A; Nikolaidou, B; Triantafyllou, A; Vamvakis, A, 2018)
"Primary aldosteronism (PA) is the most frequent cause of secondary hypertension."1.48Prevalence of primary aldosteronism in primary care: a cross-sectional study. ( Biermans, MC; Bor, HJ; de Grauw, WJ; Deinum, J; Käyser, SC; Lenders, JW; Schalk, BW; Schermer, TR, 2018)
"Primary aldosteronism (PA) is the most common endocrine form of arterial hypertension."1.48Primary aldosteronism: key characteristics at diagnosis: a trend toward milder forms. ( Adolf, C; Beuschlein, F; Hahner, S; Heinrich, DA; Januszewicz, A; Nirschl, N; Quack, I; Quinkler, M; Reincke, M; Rump, LC; Seufert, J; Sturm, L; Willenberg, HS, 2018)
"Primary aldosteronism (PA) is a common form of secondary hypertension."1.48Primary aldosteronism in patients with adrenal incidentaloma: Is screening appropriate for everyone? ( Athyros, VG; Doumas, M; Finitsis, S; Georgopoulou, V; Imprialos, KP; Kamparoudis, A; Karagiannis, A; Katsiki, N; Papadopoulos, C; Petidis, K; Petras, P; Stavropoulos, K, 2018)
"Venous thrombosis was induced by vena cava ligation."1.48Beneficial effect of combined spironolactone and quinapril treatment on thrombosis and hemostasis in 2K1C hypertensive rats. ( Aleksiejczuk, M; Chabielska, E; Gromotowicz-Poplawska, A; Marcinczyk, N; Mikita, J; Stankiewicz, A; Szemraj, J, 2018)
"Primary hyperaldosteronism as compared to other renin angiotensin aldosterone system disorders was found to be the leading cause of hypertension in young population."1.48Spectrum of renin angiotensin aldosterone system disorders in young hypertensives. ( Akram, A; Asif, N; Gilani, M; Ijaz, A; Malik, SS, 2018)
"Current threshold values for primary aldosteronism (PA) diagnostic testing are based on measuring aldosterone (PAC) using immunoassays."1.48Aldosterone LC-MS/MS Assay-Specific Threshold Values in Screening and Confirmatory Testing for Primary Aldosteronism. ( Ahmed, AH; Gordon, RD; Guo, Z; McWhinney, BC; Poglitsch, M; Stowasser, M; Ungerer, JPJ; Wolley, M, 2018)
"Primary aldosteronism affects ≈5% to 10% of hypertensive patients and has unilateral and bilateral forms."1.48Cellular and Genetic Causes of Idiopathic Hyperaldosteronism. ( Anand, SK; Guo, Z; Ito, S; Morimoto, R; Nakamura, Y; Omata, K; Rainey, WE; Sasano, H; Satoh, F; Stowasser, M; Tomlins, SA; Yamazaki, Y, 2018)
"Primary aldosteronism is a secondary hypertensive disease caused by autonomous aldosterone production that often caused by an aldosterone-producing adenoma (APA)."1.48Aldosterone and 18-Oxocortisol Coaccumulation in Aldosterone-Producing Lesions. ( Higashi, T; Kosaka, T; Mizuno, Y; Nishikawa, T; Nishimoto, K; Omura, M; Oya, M; Seki, T; Shimma, S; Suematsu, M; Sugiura, Y; Takeo, E; Yokota, M, 2018)
"Family hyperaldosteronism type I (glucocorticoids-remediable hyperaldosteronism) is a rare form of symptomatic arterial hypertension (AH), which often leads to the development of cerebrovascular complications."1.48Family hyperaldosteronism type I: a clinical case and review of literature. ( Chazova, IE; Chikladze, NM; Favorova, OO, 2018)
"Exploration showed primary hyperaldosteronism (aldosterone = 2645 pmol/l, aldosterone/renin ratio = 327 pmol/MUI), with hypersecretion of glucocorticoids."1.48[Corticosurrenaloma: an exceptional cause of primary hyperaldosteronism]. ( Alaya, W; Ammari, FL; Arfa, S; Berriche, O; Boubaker, F; Charrada, I; Elati, Z; Sfar, MH; Zantour, B, 2018)
"Aldosterone is a major mineralocorticoid hormone that plays a key role in the regulation of blood pressure and is implicated in the pathogenesis of hypertension and heart failure."1.46Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice. ( Du, N; Du, Y; Gu, H; Kowala, MC; Ma, Z; Shatara, A; Wang, J; Yi, X; Zhu, T, 2017)
"Primary aldosteronism is characterized by excess aldosterone (ALDO) secretion independent of the renin-angiotensin system and accounts for approximately 10% of hypertension cases."1.46Role and Regulation of MicroRNAs in Aldosterone-Mediated Cardiac Injury and Dysfunction in Male Rats. ( Ball, JP; Hall, ME; Kc, R; Marañon, RO; Reckelhoff, JF; Romero, DG; Syed, M; Yanes Cardozo, LL, 2017)
"Primary aldosteronism is a common cause of hypertension, which becomes refractory if undiagnosed, but potentially curable when caused by an aldosterone-producing adenoma (APA)."1.46Physiological and Pathological Roles in Human Adrenal of the Glomeruli-Defining Matrix Protein NPNT (Nephronectin). ( Brown, MJ; Garg, S; Gomez-Sanchez, CE; Gurnell, M; Johnson, TI; Teo, AE; Zhao, W; Zhou, J, 2017)
"Aldosterone is a uniquely terrestrial hormone, first appearing in lungfish, which have both gills and lungs."1.46Aldosterone and Mineralocorticoid Receptors-Physiology and Pathophysiology. ( Funder, JW, 2017)
"Primary hyperaldosteronism is a common cause of hypertension in the adult population."1.46A case of confirmed primary hyperaldosteronism diagnosed despite normal screening investigations. ( Carroll, R; Feltham, J; Gould, A; Harper, S, 2017)
"Vitamin D deficiency is associated with hypertension."1.46Nocturnal diastolic blood pressure decline is associated with higher 25-hydroxyvitamin D level and standing plasma renin activity in a hypertensive population. ( Gao, M; Li, H; Liu, H; Xu, X; Zhang, J; Zhang, M, 2017)
"Consecutive patients with diagnosed primary hyperaldosteronism from June 2006 to July 2012 in our center underwent adrenal surgeries without pre-operational adrenal venous sampling (AVS) if all the three criteria were met: (1) round- or oval-shaped occupational lesion of low density after contrast enhancement with diameter >1 cm on CT scan was located in one adrenal gland; (2) unequivocally normal contralateral adrenal gland; (3) serum potassium level lower than 3."1.46Favorable surgical outcomes of aldosterone-producing adenoma based on lateralization by CT imaging and hypokalemia: a non-AVS-based strategy. ( Cao, X; Feng, X; Li, H; Li, Y; Liu, J; Liu, L; Wei, G, 2017)
"Primary aldosteronism is recognized as a severe form of renin-independent aldosteronism that results in excessive mineralocorticoid receptor (MR) activation."1.46The Spectrum of Subclinical Primary Aldosteronism and Incident Hypertension: A Cohort Study. ( Allison, MA; Baudrand, R; Brown, JM; de Boer, IH; Ix, JH; Kestenbaum, B; Luque-Fernandez, MA; Robinson-Cohen, C; Vaidya, A, 2017)
"Primary hyperaldosteronism is an adrenal abnormality in which there is some degree of autonomy of aldosterone secretion."1.46Primary Hyperaldosteronism Due to Adrenocortical Adenoma: a Case Report. ( Amarwati, S; Naibaho, R; Pemayun, TGD; Santosa, A; Wiyati, MW, 2017)
"A total of 62 primary aldosteronism and 56 essential hypertension patients were enrolled."1.46Increased urinary excretion of the epithelial Na channel activator prostasin in patients with primary aldosteronism. ( Castagna, A; Chiariello, C; Chiecchi, L; Morandini, F; Olivieri, O; Pattini, P; Pizzolo, F; Salvagno, G; Zaltron, C; Zorzi, F, 2017)
"Liddle syndrome is a rare autosomal dominant monogenic form of hypertension."1.46Liddle syndrome: clinical and genetic profiles. ( Cui, Y; Jiang, J; Li, C; Tong, A; Wang, F, 2017)
"We described the prevalence of primary aldosteronism in our population before the change and, using the assumption of disease prevalence stability, determined the corresponding ratio cutoffs after the introduction of the new assay."1.46Novel Approach to Establishing an Aldosterone: Renin Ratio Cutoff for Primary Aldosteronism. ( Chin, A; Kline, GA; Leung, AA; Orton, DJ; Sadrzadeh, H, 2017)
"All primary aldosteronism patients were diagnosed by autonomous aldosterone secretion using confirmatory tests, and then divided into nPA (n = 130) and primary aldosteronism patients with high PAC (hPA: n = 162) using a PAC cutoff level of less than 443 pmol/l (16 ng/dl), representing the normal upper limit of PAC."1.46Plasma aldosterone level within the normal range is less associated with cardiovascular and cerebrovascular risk in primary aldosteronism. ( Hamasaki, T; Hashimoto, K; Hayashi, RD; Kajimoto, Y; Kitamura, T; Kouhara, H; Kurebayashi, S; Mukai, K; Murata, M; Nakao, M; Otsuki, M; Shimomura, I; Takeiri, S; Tamada, D; Yamamoto, T, 2017)
"Finally, the Liddle syndrome was diagnosed because of the DNA sequencing found that the proband's mother and himself had mutations P616L (c."1.46The importance of genetic counseling and genetic screening: a case report of a 16-year-old boy with resistant hypertension and severe hypokalemia. ( Jiang, L; Kuang, ZM; Liu, JH; Wang, JJ; Wang, Y; Yu, ZQ; Zeng, R; Zhou, Q, 2017)
"Primary hyperaldosteronism (PHA) is one of the most common endocrine forms of secondary hypertension."1.43Sodium interference in the determination of urinary aldosterone. ( Aldea, ML; Barallat, J; Granada, ML; Martín, MA; Pastor, MC; Rosas, I, 2016)
"HFpEF mice developed hypertension, left ventricular hypertrophy, and diastolic dysfunction and had higher myocardial natriuretic peptide expression."1.43Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue. ( Aprahamian, T; Fuster, JJ; Hulsmans, M; Li, S; Nahrendorf, M; Sam, F; Scherer, PE; Valero-Muñoz, M; Wilson, RM, 2016)
"Eplerenone treatment of patients with PA reduces blood pressure, increases serum potassium level, and improves vascular status."1.43Eplerenone improves carotid intima-media thickness (IMT) in patients with primary aldosteronism. ( Anzai, K; Kawate, H; Matsuda, Y; Matsuzaki, C; Nomura, M; Ohnaka, K; Sakamoto, R; Shibue, K; Takayanagi, R, 2016)
"Aldosterone excess can cause DNA damage in vitro and in vivo."1.43Prevalence of Malignancies in Patients With Primary Aldosteronism. ( Allolio, B; Dietz, AS; Friedrichs, N; Fuss, CT; Hahner, S; Hannemann, A; Heinze, B; Lang, K; Quack, I; Quinkler, M; Reincke, M; Rump, LC; Wallaschofski, H; Weber, K; Willenberg, HS, 2016)
" The aim of this study was to investigate whether or not the effect of β-blocker therapy on the ARR could be predicted from the dosing regimen."1.43A cross-sectional study of the effects of β-blocker therapy on the interpretation of the aldosterone/renin ratio: can dosing regimen predict effect? ( Browne, GA; Dennedy, MC; Griffin, TP; OʼShea, PM; Wall, D, 2016)
"To investigate the clinical features of adrenocortical adenoma's diagnosis and treatment in patients aged 60 years or above."1.43[Clinical diagnosis and treatment of adrenocortical adenoma in patients aged 60 years or above]. ( Huang, Z; Ji, Z; Li, J, 2016)
"Primary aldosteronism is one of the most common forms of secondary hypertension, but it is often under diagnosed, which leads to the development of cardiovascular damage, and excess costs for long-term drug treatment and management of complications."1.43The Aldosterone Renin Ratio (ARR) APP as Tool to Enhance the Detection Rate of Primary Aldosteronism. ( Bisogni, V; Rossi, GP, 2016)
"Aldosterone/renin ratio was calculated as aldosterone concentration/renin activity."1.43Association of Circulating Renin and Aldosterone With Osteocalcin and Bone Mineral Density in African Ancestry Families. ( Bunker, CH; Kammerer, CM; Kuipers, AL; Patrick, AL; Pratt, JH; Wheeler, VW; Zmuda, JM, 2016)
"To establish the cause of primary aldosteronism (PA), it is essential to distinguish unilateral from bilateral adrenal aldosterone secretion, as adrenalectomy improves aldosterone secretion and controls hypertension and hypokalemia only in the former."1.43SFE/SFHTA/AFCE consensus on primary aldosteronism, part 4: Subtype diagnosis. ( Bardet, S; Chamontin, B; Douillard, C; Hernigou, A; Joffre, F; Pagny, JY; Plouin, PF; Steichen, O, 2016)
"Aldosterone effects were prevented by the AGTR1 antagonist losartan in WT mice."1.43Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors. ( Barhoumi, T; Briet, M; Coelho, SC; Coffman, TM; Mian, MOR; Ouerd, S; Paradis, P; Rautureau, Y; Schiffrin, EL, 2016)
"Primary aldosteronism (PA) is the most common cause of endocrine hypertension that is diagnosed following a two-step process: an initial screening test, based on the serum aldosterone-to-renin ratio (ARR), followed by a relatively laborious and time-consuming confirmatory test to document autonomous aldosterone (ALD) secretion."1.43A new highly sensitive and specific overnight combined screening and diagnostic test for primary aldosteronism. ( Androulakis, II; Chrousos, GP; Kaltsas, G; Kassi, E; Kounadi, T; Markou, A; Papanastasiou, L; Piaditis, GP; Tsiavos, V; Voulgaris, N; Zachaki, A, 2016)
"Primary aldosteronism (PA) is one of the most frequent forms of secondary hypertension, associated with atherosclerosis and higher risk of cardiovascular events."1.43Enhanced Soluble Serum CD40L and Serum P-Selectin Levels in Primary Aldosteronism. ( Carnevale, R; Ciardi, A; Concistrè, A; De Toma, G; Galassi, M; Iacobellis, G; Iannucci, G; Letizia, C; Lucia, P; Marinelli, C; Petramala, L; Pignatelli, P; Violi, F; Zinnamosca, L, 2016)
"Our data indicate that in mice with Liddle syndrome, the primary site of increased Na(+) reabsorption is the DCT2/CNT."1.43In Liddle Syndrome, Epithelial Sodium Channel Is Hyperactive Mainly in the Early Part of the Aldosterone-Sensitive Distal Nephron. ( Bertog, M; Dahlmann, A; Korbmacher, C; Krueger, B; Nesterov, V; Palmisano, R, 2016)
"In patients with suspected primary aldosteronism (PA), the first diagnostic step, screening, must have high sensitivity and negative predictive value."1.43SFE/SFHTA/AFCE Consensus on Primary Aldosteronism, part 2: First diagnostic steps. ( Douillard, C; Girerd, X; Houillier, P; Nussberger, J, 2016)
"Aldosterone/renin ratio was elevated in 99 patients of whom 31 exhibited elevated supine aldosterone, as well."1.43[Renin and aldosterone determinations in hypertensive patients]. ( Bajnok, L; Bódis, B; Hussein, T; Mezősi, E; Nemes, O; Rucz, K, 2016)
"In older patients, primary aldosteronism, obstructive sleep apnoea and renal artery stenosis are more prevalent than previously thought."1.43Secondary hypertension in adults. ( Debajyoti, R; How, CH; Khoo, J; Mok, Y; Ng, AK; Puar, TH, 2016)
"To investigate the diagnostic value of plasma aldosterone-to-active-renin ratio(ARR)in combination with plasma aldosterone concentration(PAC)in the predication of aldosteronoma(APA)."1.43[An evaluation of plasma aldosterone-to-active-renin ratio in different postures in combination with aldosterone concentration in the diagnosis of aldosteronoma]. ( Ba, JM; Dou, JT; Gu, WJ; Guo, QH; Jin, N; Lyu, ZH; Mu, YM; Wang, XL; Yang, GQ; Yang, LJ; Zang, L; Zhu, J, 2016)
"Hypertension was resolved less frequently after treatment with RFA compared with laparoscopic adrenalectomy (13 of 36 versus 19 of 27 patients; P = 0·007)."1.43Radiofrequency ablation compared with laparoscopic adrenalectomy for aldosterone-producing adenoma. ( Chiu, PW; Chow, FC; Chu, CM; Kong, AP; Liu, SY; Ng, EK; Wong, SK, 2016)
"Prospective studies indicate that hyperaldosteronism is found in 20% of patients with resistant hypertension."1.43Body Mass Index Predicts 24-Hour Urinary Aldosterone Levels in Patients With Resistant Hypertension. ( Calhoun, DA; Dudenbostel, T; Ghazi, L; Li, P; Liu, M; Oparil, S, 2016)
"Primary aldosteronism (PA), the most common form of secondary hypertension, causes relevant morbidity."1.43The Clinical Value of Salivary Aldosterone in Diagnosis and Follow-Up of Primary Aldosteronism. ( Asbach, E; Bidlingmaier, M; Fourkiotis, V; Gerum, S; Lichtenauer, UD; Manolopoulou, J; Quinkler, M; Reincke, M, 2016)
"Hypertension is the prime risk factor for stroke, and primary aldosteronism (PA) is the most common cause of secondary hypertension."1.43Primary aldosteronism in patients with acute stroke: prevalence and diagnosis during initial hospitalization. ( Joki, H; Kamide, T; Kawabata, Y; Kitamura, Y; Minami, T; Miyaji, Y; Mori, K; Nakaguchi, H; Nomura, M; Sasaki, M; Seki, S; Shima, H; Tamase, A; Tanaka, F; Tsunoda, T; Yamada, M, 2016)
"To determine the prevalence of primary aldosteronism (PA) in hypertensive patients presenting to the primary care clinic at The Mount Sinai Hospital, regardless of the degree of hypertension and to identify clinical criteria that should prompt screening for PA."1.43PREVELENCE OF PRIMARY ALDOSTERONISM IN AN URBAN HYPERTENSIVE POPULATION. ( Amer, C; Bagiella, E; Boyajian, MK; Cheesman, KC; Galati, SJ; Hopkins, SM; Inabnet, WB; Krakoff, L; Levine, AC; Springer-Miller, R; Ying, TK; Zhuk, RA, 2016)
"Obesity-related hypertension is associated with increased activity of the renin-angiotensin-aldosterone system (RAAS), increasing arterial stiffness."1.42Reduction of plasma aldosterone and arterial stiffness in obese pre- and stage1 hypertensive subjects after aerobic exercise. ( Chaudhuri, D; Collier, SR; Curry, CD; Frechette, V; Gowdar, R; Ji, H; Meucci, M; Moody, AM; Sandberg, K, 2015)
"The diagnosis of primary aldosteronism (PA) among the older-aged population has posed a crucial challenge."1.42The value of losartan suppression test in the confirmatory diagnosis of primary aldosteronism in patients over 50 years old. ( Balakrishnan, P; Chen, YM; Chueh, SC; Hsein, YC; Kuo, CC; Wang, MJ; Wu, KD; Wu, VC, 2015)
"Primary aldosteronism could exert a negative feedback on prorenin secretion, of possibly different magnitude, whether it is related to an aldosterone-producing adenoma (APA) or an idiopathic hyperaldosteronism (IHA)."1.42Decreased plasma prorenin levels in primary aldosteronism: potential diagnostic implications. ( Berge, C; Bricca, G; Courand, PY; Fauvel, JP; Harbaoui, B; Khettab, F; Lantelme, P; Paget, V, 2015)
"Hypertension was improved in 97% and normalized in 38%."1.42Primary aldosteronism: functional histopathology and long-term follow-up after unilateral adrenalectomy. ( Calissendorff, J; Hamberger, B; Höög, A; Mukai, K; Thorén, M; Volpe, C; Wahrenberg, H; Zedenius, J, 2015)
"Aldosterone levels were compared to those in age-matched males undergoing FST."1.42Should aldosterone suppression tests be conducted during a particular phase of the menstrual cycle, and, if so, which phase? Results of a preliminary study. ( Ahmed, AH; Gordon, RD; Kogovsek, C; Stowasser, M; Ward, G; Wolley, M, 2015)
"If detected in patients with primary aldosteronism could implicate prorenin in the development of primary aldosteronism."1.42Expression and functional role of the prorenin receptor in the human adrenocortical zona glomerulosa and in primary aldosteronism. ( Belloni, AS; Caroccia, B; Ceolotto, G; Gonzales-Campos, A; Lenzini, L; Nussberger, J; Petrelli, L; Rainey, WE; Recarti, C; Rossi, GP; Seccia, TM, 2015)
"Primary aldosteronism is the most frequent endocrine cause of secondary hypertension."1.42Primary aldosteronism and its various clinical scenarios. ( Abad-Cardiel, M; Alvarez-Alvarez, B; García-Donaire, JA; Martell-Claros, N; Pérez, CF, 2015)
"Aldosterone has hypertrophic and profibrotic effects on the heart."1.42Plasma aldosterone and left ventricular diastolic function in treatment-naïve patients with hypertension: tissue-Doppler imaging study. ( Catena, C; Kraigher-Krainer, E; Pieske, B; Pilz, S; Sechi, LA; Tomaschitz, A; Verheyen, N, 2015)
"Resistant hypertension is common, mainly idiopathic, but sometimes related to primary aldosteronism."1.42Reliability of a Bayesian network to predict an elevated aldosterone-to-renin ratio. ( Baguet, JP; Ducher, M; Fauvel, JP; Lantelme, P; Mounier-Véhier, C; Vaisse, B, 2015)
"Primary aldosteronism (PA) is present in up to 20% of patients with treatment-resistant hypertension (TRH)."1.42Cost-Effectiveness of Therapeutic Drug Monitoring in Diagnosing Primary Aldosteronism in Patients With Resistant Hypertension. ( Arbique, D; Brinker, S; Chung, O; Das, SR; Lotan, Y; Pandey, A; Price, A; Raza, F; Velasco, A; Vongpatanasin, W, 2015)
"This agent could be useful for the treatment of hypertension, cardiovascular and renal disorders."1.42Pharmacological profile of CS-3150, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist. ( Aoki, K; Arai, K; Homma, T; Ishikawa, H; Mizuno, M; Morikawa, Y; Sada, T; Tsuruoka, H; Ubukata, N, 2015)
"Little is known about the prevalence of Liddle syndrome."1.42Prevalence of Liddle Syndrome Among Young Hypertension Patients of Undetermined Cause in a Chinese Population. ( Bian, J; Hui, RT; Jiang, XJ; Liu, YX; Song, L; Wang, LP; Wu, HY; Yang, KQ; Zhang, HM; Zhou, XL; Zou, YB, 2015)
"Although primary aldosteronism is associated with more prominent cardiac remodeling and diastolic dysfunction, the reversibility of diastolic function is unclear."1.42Circulating tissue inhibitor of matrix metalloproteinase-1 is associated with aldosterone-induced diastolic dysfunction. ( Chang, YS; Chang, YY; Chen, MF; Chen, YH; Chou, CH; Ho, YL; Hung, CS; Lin, YH; Su, MJ; Tsai, YC; Wu, KD; Wu, VC; Wu, XM, 2015)
"Primary aldosteronism (PA) is characterized by the autonomous overproduction of aldosterone."1.42Screening for primary aldosteronism in an argentinian population: a multicenter prospective study. ( Belli, SH; Chervin, RA; Contreras, LN; Cornaló, D; Costa, L; Damilano, SA; Fenili, CA; Gómez, RM; Leal Reyna, M; Lupi, SN; Martínez, MS; Nofal, MT; Pardes, EM; Rossi, MA; Ruibal, GF, 2015)
"Primary aldosteronism affects 6% of hypertensive patients."1.42[Primary aldosteronism]. ( Amar, L, 2015)
"Aldosterone suppression was assessed in 73 essential hypertensive and 46 primary aldosteronism patients."1.42Clinical validation for the aldosterone-to-renin ratio and aldosterone suppression testing using simultaneous fully automated chemiluminescence immunoassays. ( Bidlingmaier, M; Diederich, S; Dietz, A; Fischer, E; Grimminger, P; Holmes, D; Junnila, R; Manolopoulou, J; Morganti, A; Reincke, M, 2015)
"Here we describe three women with hyperaldosteronism, two who presented in pregnancy and one who presented after menopause."1.42Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations. ( Azizan, EA; Bienz, M; Brown, MJ; Garg, S; Gurnell, M; Happerfield, L; Karet Frankl, FE; Marker, A; Shaikh, LH; Teo, AE; Zhou, J, 2015)
"Aldosterone predicts new HTN, central obesity, T2DM, and use of lipid-lowering drugs in the general community and remains associated with HTN, obesity, and CKD over 4 years."1.42Aldosterone Predicts Cardiovascular, Renal, and Metabolic Disease in the General Community: A 4-Year Follow-Up. ( Bailey, KR; Buglioni, A; Burnett, JC; Cannone, V; Heublein, DM; Rodeheffer, RJ; Sangaralingham, SJ; Sarzani, R; Scott, CG, 2015)
"Primary aldosteronism (PA) is the most frequent form of secondary hypertension, but diagnostic tools for this disease still lack optimal accuracy."1.40NT-proBNP, a useful tool in hypertensive patients undergoing a diagnostic evaluation for primary aldosteronism. ( Aprili, I; Castagna, A; Chiecchi, L; Consoli, L; Guarini, P; Olivieri, O; Pavan, C; Pizzolo, F; Salvagno, GL; Zorzi, F, 2014)
"Prehypertension has been associated with adverse cerebrovascular events and brain damage."1.40Long-term prehypertension treatment with losartan effectively prevents brain damage and stroke in stroke-prone spontaneously hypertensive rats. ( He, DH; Lin, JX; Lin, LM; Ning, RB; Wang, HJ; Xu, CS; Zhang, LM, 2014)
"Hypertension is accompanied by high or low circulating AngII levels and cardiac/renal injury."1.40Autocrine and paracrine function of Angiotensin 1-7 in tissue repair during hypertension. ( Chen, Y; Liu, C; Liu, H; Meng, W; Sun, Y; Zhao, T; Zhao, W, 2014)
"Hypertension and depression are frequent comorbidities of diabetes."1.40Renin-angiotensin-aldosterone-blockade is associated with decreased use of antidepressant therapy in patients with type 1 diabetes and diabetic nephropathy. ( Ahola, AJ; Forsblom, C; Groop, PH; Harjutsalo, V, 2014)
"Aldosterone was associated with higher SBP only in Hispanics (2."1.40Association of renin and aldosterone with ethnicity and blood pressure: the Multi-Ethnic Study of Atherosclerosis. ( Allison, MA; Budoff, M; Ix, JH; Jenny, NS; Khaki, AR; McClelland, RL; Rifkin, DE; Watson, K, 2014)
"In 10 patients with primary aldosteronism, median supine ARRP was 298 (range 48-1222) and ARRD 34 (range 2."1.40Measurement of plasma renin concentration instead of plasma renin activity decreases the positive aldosterone-to-renin ratio tests in treated patients with essential hypertension. ( Bassani, N; Biganzoli, E; Gritti, A; Lonati, C; Morganti, A, 2014)
"Hypertension was cured in 24 cases (38 %), and 28 patients (45 %) showed improvement with a reduction in AM."1.40Is adrenal venous sampling mandatory before surgical decision in case of primary hyperaldosteronism? ( Baguet, JP; Chabre, O; Chaffanjon, P; Naem, N; Pirvu, A; Thony, F, 2014)
"A correct diagnosis of primary aldosteronism (PA) requires adrenal venous sampling (AVS) for the classification of subtypes (bilateral hyperplasia, BAH, or adenoma, APA)."1.40Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma. ( Brazzarola, P; Castagna, A; Cecconi, D; Chiecchi, L; D'Alessandro, A; Guarini, P; Gunasekaran, M; Morandini, F; Mulatero, P; Olivieri, O; Pizzolo, F; Veglio, F; Zolla, L, 2014)
"Canrenone is a derivative of spironolactone with lower antiandrogen activity."1.40Aldosterone receptor blockers spironolactone and canrenone: two multivalent drugs. ( Armanini, D; Bordin, L; Clari, G; Donà, G; Sabbadin, C, 2014)
"Adrenal hyperplasia was apparent on post-mortem histopathology."1.40Hypokalaemia in a hyperthyroid domestic shorthair cat with adrenal hyperplasia. ( Elwood, C; Fryers, A, 2014)
"Primary aldosteronism (PA), the most frequent form of secondary hypertension, is characterized by a higher rate of cardiovascular (CV) events than essential hypertension (EH)."1.40Primary aldosteronism and essential hypertension: assessment of cardiovascular risk at diagnosis and after treatment. ( Boscaro, M; Ceccoli, L; di Tizio, V; Giacchetti, G; Ronconi, V; Turchi, F, 2014)
"When hexamethonium was used to assess autonomic control of MAP, no differences in the decrease of MAP in response to ganglionic blockade were detected during the induction."1.40CNS neuroplasticity and salt-sensitive hypertension induced by prior treatment with subpressor doses of ANG II or aldosterone. ( Beltz, T; Clayton, SC; Johnson, AK; Xue, B; Zhang, Z, 2014)
"Aldosterone-salt treatment induces not only hypertension but also extensive inflammation that contributes to fibrosis in the rat kidney."1.40Mizoribine ameliorates renal injury and hypertension along with the attenuation of renal caspase-1 expression in aldosterone-salt-treated rats. ( Doi, S; Doi, T; Kohno, N; Masaki, T; Nakashima, A; Ueno, T; Yokoyama, Y, 2014)
"From 257 consecutive primary aldosteronism patients, we identified 176 who had both a diagnosis of APA by the 'four corners' criteria and high-quality echocardiographic data."1.40KCNJ5 gene somatic mutations affect cardiac remodelling but do not preclude cure of high blood pressure and regression of left ventricular hypertrophy in primary aldosteronism. ( Cesari, M; Cicala, MV; Iacobone, M; Kuppusamy, M; Letizia, C; Mantero, F; Mareso, S; Pessina, AC; Rossi, GP; Sciomer, S; Seccia, TM; Zinnamosca, L, 2014)
"The prevalence of primary aldosteronism (PA) in hypertensive patients varies according to diagnostic testing and ascertained normal cut-offs."1.40Primary aldosteronism in hypertensive patients: clinical implications and target therapy. ( Chrousos, G; Dasou, A; Fountoulakis, S; Gouli, A; Gryparis, A; Kaltsas, G; Kounadi, T; Markou, A; Papanastasiou, L; Pappa, T; Piaditis, G; Samara, C; Tsiama, V; Tsounas, P; Zografos, G, 2014)
"Primary aldosteronism, an important form of secondary hypertension, is associated with significant increase of cardiovascular risk (ischaemic heart, cerebrovascular events, arrhythmias) (relative risk 4."1.40Oxidative stress in patients affected by primary aldosteronism. ( Carnevale, R; Concistrè, A; De Toma, G; Letizia, C; Marinelli, C; Petramala, L; Pignatelli, P; Settevendemmie, A; Tonnarini, G; Violi, F; Zinnamosca, L, 2014)
"Primary aldosteronism (PA) is common in young or middle-aged hypertensive patients, but PA among the elderly has recently become more common."1.40The influence of aging on the diagnosis of primary aldosteronism. ( Hongyo, K; Ito, N; Kamide, K; Kawai, T; Nakama, C; Onishi, M; Rakugi, H; Sugimoto, K; Takeya, Y; Yamamoto, K, 2014)
"In 33 hypertensive patients with type 2 diabetes mellitus treated with a calcium channel blocker other than cilnidipine, we evaluated the influence of switching to cilnidipine on blood pressure, heart rate, catecholamine, plasma renin and aldosterone concentration, brain natriuretic peptide, urine liver-type fatty acid binding protein, and urinary albumin excretion ratio in the same patients by a cross-over design."1.40Effects of cilnidipine on sympathetic nerve activity and cardiorenal function in hypertensive patients with type 2 diabetes mellitus: association with BNP and aldosterone levels. ( Ichihara, A; Itoh, H; Nishimura, T; Sekioka, R; Tanaka, M, 2014)
"In primary aldosteronism (PA), lateralized aldosterone excess can be treated with aldosterone antagonists or surgery, which raises the question as to whether surgery or medications should be the preferred management."1.39Medical or surgical therapy for primary aldosteronism: post-treatment follow-up as a surrogate measure of comparative outcomes. ( Dias, VC; Harvey, A; Kline, GA; Pasieka, JL; So, B, 2013)
"Aldosterone excess has a direct negative effect on β-cell function in patients with PA."1.39Aldosterone excess impairs first phase insulin secretion in primary aldosteronism. ( Adolf, C; Beuschlein, F; Bidlingmaier, M; Fischer, E; Pallauf, A; Reincke, M; Seissler, J; Then, C, 2013)
"Hypertension is a frequent complication of type 2 diabetes mellitus (DM) because of the close etiological relationship between these two diseases."1.39Prevalence and clinical characteristics of primary aldosteronism in Japanese patients with type 2 diabetes mellitus and hypertension. ( Akehi, Y; Murase, K; Nagaishi, R; Nomiyama, T; Takenoshita, H; Yanase, T, 2013)
"Hyperkalemia is a potentially serious complication following adrenalectomy of aldosterone-producing adenomas (APA)."1.39Incidence and factors of post-adrenalectomy hyperkalemia in patients with aldosterone producing adenoma. ( Cheng, CJ; Chiang, WF; Lin, MY; Lin, SH; Sun, GH; Sung, CC; Wu, ST, 2013)
"Rhodiola Sacra may prevent left ventricular remodeling in SHRs, which is probably attributed to blood pressure lowering and inhibition of RAS, especially myocardial RAS."1.39[Effect of Rhodiola Sacra on left ventricular remodeling and its mechanism in spontaneously hypertensive rats]. ( Chen, XP; Liu, K; Yang, R, 2013)
"The spironolactone treatment group demonstrated significant increases in heart rate and cardiac output and a decrease in cardiac index compared to SHR controls."1.39Echocardiographic effects of eplerenone and aldosterone in hypertensive rats. ( Dostal, DE; Jewell, C; Song, J; Watson, LE, 2013)
"Aldosterone values were adjusted statistically for age, sex, and the urinary sodium/creatinine ratio."1.39Bimodal aldosterone distribution in low-renin hypertension. ( Adlin, EV; Braitman, LE; Vasan, RS, 2013)
"Primary aldosteronism (PA) is the most common etiology of endocrine hypertension (HTN), and recent prevalence studies suggest that it may be under-diagnosed."1.39Primary aldosteronism: emerging trends. ( Cheesman, KC; Galati, SJ; Hopkins, SM; Levine, AC; Zhuk, RA, 2013)
"Hypertension is highly prevalent and remains poorly controlled."1.39Blood pressure control 1 year after referral to a hypertension specialist. ( Cohen, DL; Denker, MG; Haddad, DB; Townsend, RR, 2013)
"Primary aldosteronism (PA) is the most common endocrine form of hypertension and may carry an increased risk of atrial flutter or fibrillation (AFF)."1.39Prospective appraisal of the prevalence of primary aldosteronism in hypertensive patients presenting with atrial flutter or fibrillation (PAPPHY Study): rationale and study design. ( Belfiore, A; Bernini, G; Caielli, P; Cipollone, F; Cottone, S; Ferri, C; Gallina, V; Giacchetti, G; Grassi, G; Leoni, L; Letizia, C; Maccario, M; Mantero, F; Morganti, A; Muiesan, ML; Olivieri, O; Palumbo, G; Pengo, M; Pessina, AC; Ragazzo, F; Rizzoni, D; Rossi, E; Rossi, GP; Seccia, TM; Sechi, L; Volpe, M, 2013)
"Primary hyperaldosteronism is most commonly due to a solitary cortical adenoma."1.39Adrenal histologic findings show no difference in clinical presentation and outcome in primary hyperaldosteronism. ( Abraham, SB; Barak, S; Kebebew, E; Mathur, A; Nilubol, N; Quezado, M; Stratakis, CA; Webb, RC; Weisbrod, AB, 2013)
"Primary aldosteronism (PA) is a common cause of secondary hypertension but the reported prevalence varies."1.39Screening for primary aldosteronism in a primary care unit. ( Hamberger, B; Thorén, M; Volpe, C; Wahrenberg, H, 2013)
"Primary hyperaldosteronism is the most common cause of secondary hypertension."1.39Hypertension caused by primary hyperaldosteronism: increased heart damage and cardiovascular risk. ( Abad-Cardiel, M; Alvarez-Álvarez, B; Fernández, C; Fernández-Cruz, A; Luque-Fernandez, L; Martell-Claros, N, 2013)
"Treatment with aldosterone did not alter mitochondrial respiratory function but accelerated Ca(2+)-induced MPT in SSM, but not IFM, compared with healthy old and young beagles."1.39Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs: effects of aging and long-term aldosterone infusion. ( Asemu, G; Cox, JW; Dabkowski, ER; Hecker, PA; Hoppel, CL; O'Connell, KA; Rastogi, S; Ribeiro, RF; Sabbah, HN; Shekar, KC; Stanley, WC; Xu, W, 2013)
"Hyperaldosteronism was defined as a plasma renin activity of < 1 ng/mL/h and urinary aldosterone level of ≥ 12 μg/24 h."1.39Increased dietary sodium is related to severity of obstructive sleep apnea in patients with resistant hypertension and hyperaldosteronism. ( Batlouni, M; Calhoun, DA; Gordon, RD; Harding, SM; Oparil, S; Pimenta, E; Stowasser, M; Zhang, B, 2013)
"Aldosterone is a major mineralocorticoid hormone that plays a key role in the regulation of electrolyte balance and blood pressure."1.39Structural insights into aldosterone synthase substrate specificity and targeted inhibition. ( Arrowsmith, CH; Edwards, AM; Gilep, AA; Park, HW; Shen, L; Strushkevich, N; Usanov, SA, 2013)
" On the other hand, under the condition of Ang II-induced hypertension, administration of a hypotensive dosage of cilnidipine showed no effect on the plasma aldosterone levels, whereas a hypotensive dosage of nifedipine significantly increased the plasma aldosterone levels."1.38L/N-type calcium channel blocker suppresses reflex aldosterone production induced by antihypertensive action. ( Aritomi, S; Konda, T; Yoshimura, M, 2012)
"Aldosterone (Aldo) is an important active hormone in the renin-angiotensin-aldosterone system and plays a vital role in the development of hypertension, heart failure and other cardiovascular diseases."1.38Endogenous aldosterone is involved in vascular calcification in rat. ( Cai, Y; Jia, LX; Qi, YF; Tang, CS; Wang, X; Wu, SY; Xiao, CS; Yu, YR, 2012)
"Primary aldosteronism (PA) is the most frequent cause of secondary hypertension, and is associated with more prominent vascular stiffness and atherosclerosis."1.38Adrenalectomy improves increased carotid intima-media thickness and arterial stiffness in patients with aldosterone producing adenoma. ( Chen, A; Chueh, SC; Ho, YL; Lee, JK; Lin, LY; Lin, WC; Lin, YH; Lo, MT; Su, TC; Wang, PC; Wu, KD; Wu, VC; Wu, XM, 2012)
"Spironolactone treatment significantly increased aldosterone levels in males and females independent of the sodium content of the diet."1.38Sex-specific effects of spironolactone on blood pressure in gonadectomized male and female Wistar rats. ( Bartel, C; Götz, F; Hofmann, PJ; Kienitz, T; Michaelis, M; Quinkler, M, 2012)
"Currently, if hypertension is present in 20% of the population, PA will account for 2%; of these PA patients only 1% are ever screened, let alone diagnosed and treated, and the remaining 99% suboptimally treated, if at all."1.38Primary aldosteronism: are we missing the wood for the trees? ( Funder, JW, 2012)
"Aldosterone has been linked to the deleterious cardiovascular effects of obesity in humans."1.38The development of hypertension and hyperaldosteronism in a rodent model of life-long obesity. ( Dorrance, AM; Fink, GD; Garver, H; Haywood, JR; Laimon-Thomson, EL; McClain, JL; Northcott, CA; Pires, PW; Rainey, WE; Rigsby, CS, 2012)
"Myelolipomas are adrenal tumors composed of both adipose and hematopoietic tissues which are rarely associated with primary aldosteronism (PA)."1.38A case of myelolipoma with bilateral adrenal hyperaldosteronism cured after unilateral adrenalectomy. ( Arai, H; Fujii, T; Fukuda, Y; Honda, K; Inuzuka, M; Kanamoto, N; Kojima, K; Kondo, E; Mikami, Y; Miura, M; Nakao, K; Sasano, H; Sone, M; Sonoyama, T; Tamura, N; Taura, D; Ueda, Y; Yamada, G; Yamashita, Y; Yasoda, A, 2012)
"Amiloride treatment also reduced high blood pressure caused by the high-salt diet in these mice."1.38Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice. ( Chen, S; Cui, Y; Jiang, J; Peng, J; Shen, J; Wang, W; Wu, Q, 2012)
"The prevalence of primary aldosteronism in unselected hypertensive patients is currently unknown."1.38Screening for primary aldosteronism in hypertensive subjects: results from two German epidemiological studies. ( Beuschlein, F; Bidlingmaier, M; Biffar, R; Döring, A; Felix, SB; Friedrich, N; Hannemann, A; Manolopoulou, J; Meisinger, C; Nauck, M; Peters, A; Reincke, M; Rettig, R; Seissler, J; Spyroglou, A; Völzke, H; Wallaschofski, H; Wichmann, HE, 2012)
"Hyperaldosteronism combined with hypertension favored the macrophage infiltration (CD68(+) cells) in heart, and enhanced the mRNA level of monocyte chemoattractant protein 1, osteopontin, and galectin 3."1.38Aldosterone inhibits antifibrotic factors in mouse hypertensive heart. ( Azibani, F; Benard, L; Carrier, L; Chatziantoniou, C; Delcayre, C; Fazal, L; Launay, JM; Merval, R; Polidano, E; Samuel, JL; Schlossarek, S; Tournoux, F, 2012)
"Arterial hypertension (AH) induces cardiac hypertrophy and reactivation of "fetal" gene expression."1.38Aldosterone inhibits the fetal program and increases hypertrophy in the heart of hypertensive mice. ( Azibani, F; Carrier, L; Chatziantoniou, C; Coutance, G; Delcayre, C; Devaux, Y; Fazal, L; Launay, JM; Merval, R; Polidano, E; Samuel, JL; Schlossarek, S; Solal, AC, 2012)
"Moreover, aldosterone-producing adrenocortical carcinomas without hypertension are exceedingly rare, with only two previously reported cases."1.38Aldosterone-producing adrenocortical carcinoma without hypertension. ( Bae, SB; Kim, SJ; Kim, YJ; Seo, SW; Song, MS, 2012)
"Hypertension is characterized by left ventricular (LV) hypertrophy (LVH)."1.38Interferon-γ ablation exacerbates myocardial hypertrophy in diastolic heart failure. ( Baid, S; Garcia, AG; Heo, J; Murthy, NR; Ouchi, N; Sam, F; Wilson, RM, 2012)
"Primary hyperaldosteronism or Conn syndrome is the syndrome formed from the triad of hypertension, hypokalemia, and metabolic alkalosis."1.38Sixteen years experience in six cases of Conn syndrome in Jakarta. ( Siregar, P, 2012)
"Primary aldosteronism caused by an aldosterone producing adrenal tumor/aldosteronoma (APA), is a potentially curable form of hypertension, via unilateral adrenalectomy."1.38Persistent hypertension after adrenalectomy for an aldosterone-producing adenoma: weight as a critical prognostic factor for aldosterone's lasting effect on the cardiac and vascular systems. ( Carter, Y; Chen, H; Roy, M; Sippel, RS, 2012)
"Obesity is a major risk factor for hypertension."1.38Increasing peripheral insulin sensitivity by protein tyrosine phosphatase 1B deletion improves control of blood pressure in obesity. ( Ali, MI; Belin de Chantemèle, EJ; Fulton, DJ; Mintz, JD; Rainey, WE; Stepp, DW; Tremblay, ML, 2012)
"Insulin resistance was calculated using the homeostasis model assessment (HOMA-IR)."1.37Cardiovascular correlates of insulin resistance in normotensive and hypertensive African Americans. ( Grim, CE; Kidambi, S; Kotchen, JM; Kotchen, TA; Krishnaswami, S, 2011)
"Aldosterone treatment did not modify NO or TxB(2) release, but it did increase superoxide anion and 6-keto-PGF(1alpha) release in mesenteric resistance arteries from both strains."1.37Aldosterone alters the participation of endothelial factors in noradrenaline vasoconstriction differently in resistance arteries from normotensive and hypertensive rats. ( Avendaño, MS; Balfagón, G; Blanco-Rivero, J; Salaíces, M; Sastre, E; Velázquez, K; Xavier, FE; Yela, R, 2011)
"To evaluate the prevalence of primary aldosteronism (PA) in newly diagnosed and untreated hypertensive patients in primary care using the aldosterone/renin ratio (ARR), and to assess clinical and biochemical characteristics in patients with high and normal ARR."1.37Primary aldosteronism among newly diagnosed and untreated hypertensive patients in a Swedish primary care area. ( Bergenfelz, A; Isaksson, A; Nerbrand, C; Valdemarsson, S; Westerdahl, C, 2011)
"Current data on primary aldosteronism (PA) from Asian populations are scarce."1.37Verification and evaluation of aldosteronism demographics in the Taiwan Primary Aldosteronism Investigation Group (TAIPAI Group). ( Chang, CC; Chang, HW; Chu, TS; Chueh, SC; Huang, KH; Kao, TW; Kuo, CC; Lai, CF; Lee, TY; Lin, CY; Lin, WC; Lin, YH; Lu, CC; Tsai, CW; Wang, SM; Wang, WJ; Wu, KD; Wu, MS; Wu, VC; Yang, WS, 2011)
"Obesity has been recognized as an independent risk factor for arterial hypertension."1.37Arterial hypertension in obesity: relationships with hormone and anthropometric parameters. ( De Pergola, G; Guida, P; Nardecchia, A; Silvestris, F, 2011)
"Familial hyperaldosteronism type 1 is an autosomal dominant disorder attributed to a chimeric CYP11B1/CYP11B2 gene (CG)."1.37Frequency of familial hyperaldosteronism type 1 in a hypertensive pediatric population: clinical and biochemical presentation. ( Aglony, M; Avalos, C; Avila, A; Bancalari, R; Bolte, L; Brinkmann, K; Campino, C; Carvajal, CA; Fardella, CE; García, H; Giadrosich, V; Inostroza, A; Loureiro, C; Martínez-Aguayo, A; Mericq, V; Perez, V; Rocha, A; Trejo, P, 2011)
"Glucocorticoid-remediable aldosteronism (GRA) is caused by the presence of a chimeric gene originating from an unequal cross-over between the CYP11B1 and CYP11B2 genes."1.37Diagnosis of glucocorticoid-remediable aldosteronism in hypertensive children. ( Haag, C; Kamrath, C; Maser-Gluth, C; Schulze, E, 2011)
"1."1.37Association of the aldosterone synthase gene -344T>C polymorphism with essential hypertension and glucose homeostasis: a case-control study in a Han Chinese population. ( Chen, HY; Gao, X; Li, XM; Ling, Y; Liu, Y; Lu, DR; Lu, ZQ; Yi, QL, 2011)
"Hypertension is the most common cardiovascular disease worldwide and is a major cause of morbidity and mortality."1.37Plasma catecholamines in Nigerians with primary hypertension. ( Adebiyi, AA; Akinosun, OM; Falase, AO; Nwafor, CE, 2011)
"Hyperaldosteronism was classified as an aldosterone/renin ratio (ARR) ≥ 30."1.37Resistant hypertension and undiagnosed primary hyperaldosteronism detected by use of a computerized database. ( Garcia, EA; Lopez, JR; Meier, JL; Siegel, D; Swislocki, AL, 2011)
"Hypertension is a leading contributor to cardiovascular mortality worldwide."1.37Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway. ( Ando, K; Ayuzawa, N; Fujita, T; Ishikawa, A; Ishizawa, K; Kawarazaki, H; Kawarazaki, W; Miyoshi, J; Mu, S; Muraoka, K; Nagase, M; Shibata, S; Shimosawa, T; Takai, Y; Takeuchi, M; Yoshida, S, 2011)
"Primary aldosteronism (PA) is associated with a higher incidence of cardiovascular events, probably through mineralocorticoid receptor (MR)-dependent endothelial cell dysfunction, in comparison with essential hypertension (EH)."1.37Endothelial progenitor cells in primary aldosteronism: a biomarker of severity for aldosterone vasculopathy and prognosis. ( Chen, JW; Chen, YL; Huang, PH; Kuo, CC; Kuo, YS; Lee, BC; Liang, CJ; Lin, SJ; Lin, SL; Lin, YH; Lo, SC; Sun, YY; Tsai, CT; Wu, EL; Wu, KD; Wu, VC, 2011)
"Spironolactone treatment reversed all the above effects."1.37A role for cardiotrophin-1 in myocardial remodeling induced by aldosterone. ( Cachofeiro, V; Díez, J; Fortuno, MA; Lahera, V; López-Andrés, N; Martin-Fernandez, B; Rossignol, P; Zannad, F, 2011)
"Resistant hypertension has evolved as an important global health care problem."1.37What is the role of aldosterone excess in resistant hypertension and how should it be investigated and treated? ( Sica, DA, 2011)
"Aldosterone plays a role in hypertension, and hypertension is prevalent in patients with insulin resistance."1.37Plasma aldosterone levels and development of insulin resistance: prospective study in a general population. ( Adachi, H; Enomoto, M; Esaki, E; Fukami, A; Hirai, Y; Imaizumi, T; Jacobs, DR; Kasahara, A; Kumagae, S; Kumagai, E; Nanjo, Y; Ogata, K; Ohbu-Murayama, K; Otsuka, M; Tsukagawa, E; Yokoi, K; Yoshikawa, K, 2011)
"Primary aldosteronism (PA) is a possible cause of endocrine hypertension."1.37[Aldosterone/renin ratio in the diagnosis of primary aldosteronism]. ( Catay, E; Honnorat, E; Izquierdo, A; Popescu, BM; Ríos, MC; Rodríguez Cuimbra, S; Sotelo, M, 2011)
"S-Aldosterone was normalized."1.36Long-term effects of surgical correction of adrenal hyperplasia and adenoma causing primary aldosteronism. ( Andreasson, S; Botling, J; Hägg, A; Hellman, P; Hennings, J; Sundin, A, 2010)
"Metabolic syndrome was defined according to ATPIII criteria."1.36Metabolic syndrome in primary aldosteronism and essential hypertension: relationship to adiponectin gene variants. ( Agostinelli, L; Boscaro, M; Di Mattia, D; Giacchetti, G; Rilli, S; Ronconi, V; Turchi, F, 2010)
"Insulin resistance is associated with nonalcoholic fatty liver disease (NAFLD) and may play a role in its pathophysiology."1.36Nonalcoholic fatty liver disease in primary aldosteronism: a pilot study. ( Bertello, C; Catena, C; Dalla Pozza, A; Ermani, M; Fabris, B; Fallo, F; Mulatero, P; Sabato, N; Sechi, LA; Sonino, N; Tecchio, M; Tona, F, 2010)
"Hypertension was induced in Cyp1a1-Ren-2 rats through dietary administration of the natural xenobiotic indole-3-carbinol (0."1.36Inappropriately high circulating and intrarenal angiotensin II levels during dietary salt loading exacerbate hypertension in Cyp1a1-Ren-2 transgenic rats. ( Bürgelová, M; Cervenka, L; Erbanová, M; Husková, Z; Kramer, HJ; Mullins, JJ; Opocenský, M; Thumová, M; Vanourková, Z, 2010)
"After a positive screening, primary aldosteronism diagnosis needs confirmation by an inhibitory test such as intravenous saline load (ivSLT)."1.36Effects of female sex hormones and contraceptive pill on the diagnostic work-up for primary aldosteronism. ( Chiecchi, L; Corrocher, R; Franchi, M; Guarini, P; Guidi, GC; Memmo, A; Olivieri, O; Pavan, C; Pizzolo, F; Raffaelli, R, 2010)
"In 22 patients with unilateral primary aldosteronism (UPA), unilateral laparoscopic adrenalectomy (ADX) not only corrected hypokalemia and led to cure or improvement of hypertension, but also significantly improved quality of life (QOL)."1.36Improved quality of life, blood pressure, and biochemical status following laparoscopic adrenalectomy for unilateral primary aldosteronism. ( Gordon, RD; Kogovsek, C; Robson, D; Stowasser, M; Sukor, N, 2010)
"Although hypokalemia is a common clinical problem, symptoms generally do not become manifest unless the serum potassium (K) falls rapidly."1.36[Clinical characteristics of five elderly patients with severe hypokalemia induced by glycyrrhizin derivatives]. ( Hatanaka, M; Kadoya, H; Matsuda, J; Namba, T; Takahashi, A; Takeji, M; Yamamoto, T; Yamauchi, A, 2010)
"Aldosterone is a prerequisite for this action."1.36Pathogenesis of hypertension: interactions among sodium, potassium, and aldosterone. ( Büssemaker, E; Hausberg, M; Hillebrand, U; Oberleithner, H; Pavenstädt, H, 2010)
"Azelnidipine treatment in drug-naïve (DN) cases significantly decreased systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR)."1.36Plasma renin activity and aldosterone concentration are not altered by the novel calcium channel antagonist, azelnidipine, in hypertensive patients. ( Araki, E; Goto, R; Kondo, T; Miyamura, N; Ono, K; Sonoda, K; Takaki, Y; Yasuda, T; Yatsuda, R, 2010)
"Resistant hypertension was defined as the failure to control systolic and/or diastolic BP despite at least three different classes of antihypertensive agents, including a diuretic."1.36RGS2 expression and aldosterone: renin ratio modulate response to drug therapy in hypertensive patients. ( Calò, LA; Ceolotto, G; Macchini, L; Papparella, I; Realdi, A; Sartori, M; Semplicini, A; Strapazzon, G, 2010)
"Felodipine has a protective effect on the myocardium and kidney as evidenced by decreased perivascular inflammation, myocardial necrosis and fibrosis."1.36Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats. ( Franco, M; Janicki, JS; Matsubara, BB; Matsubara, LS, 2010)
"Primary aldosteronism (PA) is a common form of secondary hypertension."1.36The prevalence of metabolic syndrome and its components in two main types of primary aldosteronism. ( Dvoráková, J; Holaj, R; Masek, M; Petrák, O; Rosa, J; Somlóová, Z; Strauch, B; Vlková, J; Wichterle, D; Widimský, J; Zelinka, T, 2010)
"Primary aldosteronism (PA) is a frequent cause of secondary hypertension and is amenable to surgical intervention when it is caused by aldosterone-producing adenoma (APA)."1.36Predictors of resolution of hypertension after adrenalectomy in patients with aldosterone-producing adenoma. ( Kim, RM; Lee, J; Soh, EY, 2010)
"Aldosterone and LVH were investigated in 240 and 110 subjects respectively."1.36Association of HSD3B1 and HSD3B2 gene polymorphisms with essential hypertension, aldosterone level, and left ventricular structure. ( Aoi, N; Izumi, Y; Matsumoto, K; Nakayama, T; Sato, M; Sato, N; Shimodaira, M; Soma, M, 2010)
"Aldosterone has been correlated with increased oxidative stress, endothelial inflammation, and fibrosis, particularly in patients with heart disease."1.36Increased levels of oxidative stress, subclinical inflammation, and myocardial fibrosis markers in primary aldosteronism patients. ( Becerra, E; Carvajal, CA; Fardella, CE; García, L; Jalil, J; Lavandero, S; Mellado, R; Mosso, L; Ocaranza, MP; Solis, M; Stehr, CB, 2010)
"Hyperaldosteronism (PRA < 1 ng x mL(-1) x h(-1) and UAldo > or = 12 microg/24-h) prevalence was 28% and OSA prevalence was 77%."1.36Severity of obstructive sleep apnea is related to aldosterone status in subjects with resistant hypertension. ( Ahmed, MI; Calhoun, DA; Cofield, SS; Gaddam, KK; Gonzaga, CC; Harding, SM; Oparil, S; Pimenta, E; Thomas, SJ, 2010)
"Glucocorticoid-remediable aldosteronism (GRA) is an autosomal-dominant inheritable form of hyperaldosteronism with early onset hypertension."1.36Genetic analyses of the chimeric CYP11B1/CYP11B2 gene in a Korean family with glucocorticoid-remediable aldosteronism. ( Jang, HW; Jo, YS; Kim, MK; Kim, SY; Lee, IS; Lee, JH; Lee, YH, 2010)
"Primary aldosteronism is more common than previously recognized but much less common than most experts in this arena have recently stated."1.36Current diagnosis and treatment of primary aldosteronism. ( Kaplan, NM, 2010)
"Resistant hypertension is a common clinical problem and greatly increases the risk of target organ damage."1.35Characterization of resistant hypertension: association between resistant hypertension, aldosterone, and persistent intravascular volume expansion. ( Aban, I; Calhoun, DA; Gaddam, KK; Nishizaka, MK; Oparil, S; Pimenta, E; Pratt-Ubunama, MN, 2008)
"The diagnosis of primary hyperaldosteronism due to microadenoma or unilateral adrenal hyperplasia can be challenging, since hypokalaemic alkalosis, high plasma aldosterone and a definite adenoma on imaging may all be absent."1.35Primary hyperaldosteronism due to adrenal microadenoma: a curable cause of refractory hypertension. ( Appleton, DS; Brown, MJ; Coghill, S; Jamieson, N; Lomas, DJ; Myint, KS; Taylor, KP; Watts, M, 2008)
"A clear reduction of BP values was recorded after both the first and the second month of treatment with kanrenoate, with the maximal effect obtained when the dosage titration at 100 mg/day was accomplished."1.35Menopause not aldosterone-to-renin ratio predicts blood pressure response to a mineralocorticoid receptor antagonist in primary care hypertensive patients. ( Blengio, GS; Ciacciarelli, A; Corrocher, R; Falcone, S; Olivieri, O; Pizzolo, F; Signorelli, D, 2008)
"Primary aldosteronism (PA) represents a clinical model useful in assessing the effect of aldosterone increase on LVM."1.35Inappropriate left ventricular mass in patients with primary aldosteronism. ( Agabiti-Rosei, C; Agabiti-Rosei, E; Aggiusti, C; Belotti, E; Castellano, M; Galbassini, G; Monteduro, C; Muiesan, ML; Paini, A; Rizzoni, D; Salvetti, M, 2008)
"Weight loss is associated with reduction of blood pressure and of PRA and aldosterone levels in obese hypertensive subjects."1.35Effect of weight loss through laparoscopic gastric banding on blood pressure, plasma renin activity and aldosterone levels in morbid obesity. ( Dall'Asta, C; Folli, F; Manunta, P; Marchi, M; Paganelli, M; Pizzocri, P; Pontiroli, AE; Vedani, P, 2009)
"Considering the role of aldosterone in diabetic nephropathy, genetic polymorphism of this gene may contribute to the development and progression of diabetic nephropathy."1.35Polymorphism of the aldosterone synthase gene is not associated with progression of diabetic nephropathy, but associated with hypertension in type 2 diabetic patients. ( Cha, DR; Kang, YS; Kim, HK; Ko, GJ; Lee, MH; Song, HK, 2008)
"Recent data suggest that primary aldosteronism is found in about 10% of hypertensive patients managed in primary care and diagnosed in about 20% of treated but uncontrolled hypertensive patients."1.35[Primary hyperaldosteronism in hypertension]. ( Girerd, X, 2008)
"Primary aldosteronism (PA) may account for as much as 6-20% of cases of refractory hypertension referred to hypertension clinics."1.35The cutoff value of aldosterone-to-renin ratio for the diagnosis of primary aldosteronism in patients taking antihypertensive medicine. ( Fukuchi, K; Horio, T; Iwanaga, Y; Kamide, K; Kawano, Y; Nakahama, H; Nakamura, S; Nakata, H; Niizuma, S; Yoshihara, F, 2008)
"Both fibrinogen and PAI-1 were independent predictors of the presence of organ damage and their inclusion in a multivariate model eliminated PRA and aldosterone as independent predictors."1.35Relationship of plasma renin with a prothrombotic state in hypertension: relevance for organ damage. ( Casanova-Borca, A; Catena, C; Chiuch, A; Colussi, G; Di Fabio, A; Nadalini, E; Novello, M; Sechi, LA; Uzzau, A, 2008)
"Aldosterone promotes renal fibrosis via the mineralocorticoid receptor (MR), thus contributing to hypertension-induced nephropathy."1.35Hypertension-induced renal fibrosis and spironolactone response vary by rat strain and mineralocorticoid receptor gene expression. ( Camp, JR; Cavallari, LH; Fashingbauer, LA; Geenen, DL; King, ST, 2008)
"Treatment with camostat mesilate or FOY-251 decreased equivalent current (Ieq) in M-1 cells in a dose-dependent manner and inhibited the protease activity of prostasin in vitro."1.35Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension. ( Adachi, M; Kakizoe, Y; Kitamura, K; Ko, T; Maekawa, A; Miyoshi, T; Shiraishi, N; Tomita, K; Wakida, N, 2009)
"Findings suggested that primary hyperaldosteronism should be considered as a possible cause in ferrets with hypokalemia, hypertension, and an adrenal gland mass."1.35Primary hyperaldosteronism in a domestic ferret with an adrenocortical adenoma. ( Desmarchelier, M; Dunn, M; Lair, S; Langlois, I, 2008)
"Until recently, primary hyperaldosteronism was considered a rare cause of secondary hypertension."1.35Prevalence of primary hyperaldosteronism in a systemic arterial hypertension league. ( Faria, Mdos S; Figueiredo Neto, JA; Lopes, Mde C; Memória, EV; Oliveira, TC; Ribeiro, MJ; Salgado Filho, N, 2009)
"To evaluate the prevalence of left ventricular hypertrophy (LVH) and left ventricular geometry in a group of 293 hypertensive patients with stage 2-5 chronic kidney disease (CKD), compared with 289 essential hypertensive patients with normal renal function."1.35Left ventricular hypertrophy and geometry in hypertensive patients with chronic kidney disease. ( Cerasola, G; Cottone, S; Cusimano, P; Mulè, G; Nardi, E; Palermo, A, 2009)
"Primary aldosteronism (PA) is a secondary hypertension characterized by autonomous aldosterone hypersecretion from adrenocortical adenoma and/or hyperplasia."1.35Endothelial dysfunction is related to aldosterone excess and raised blood pressure. ( Hirata, Y; Tsuchiya, K; Yoshimoto, T, 2009)
"Adrenal masses in Gardner's syndrome are rare, and few have displayed clinical manifestations."1.35Hyperaldosteronism in an adolescent with Gardner's syndrome. ( Felner, EI; Gow, K; Taweevisit, M, 2009)
"The hyperaldosteronism of apc(Min/+) mice was paralleled by significantly elevated plasma volume and blood pressure."1.35Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC. ( Bhandaru, M; Kempe, DS; Kuhl, D; Lang, F; Rexhepaj, R; Rotte, A, 2009)
"Primary aldosteronism (PA) is the most common secondary cause of hypertension that has recently been implicated in alterations of the immune system and progression of cardiovascular disease."1.35Primary aldosteronism can alter peripheral levels of transforming growth factor beta and tumor necrosis factor alpha. ( Carvajal, CA; Castillo, CR; Contreras, FJ; Fardella, CE; Herrada, AA; Kalergis, AM; Mosso, LM; Stehr, CB, 2009)
"Primary aldosteronism (PA) is caused by autonomous hypersecretion of aldosterone from the adrenal cortex, classically from an adenoma, resulting in sodium and water retention, hypokalaemia and raised blood pressure."1.35Atrial fibrillation in primary aldosteronism. ( Beevers, DG; Karthikeyan, VJ; Lip, GY; Watson, T, 2009)
"Normokalaemia does not exclude primary aldosteronism as the underlying cause of hypertension."1.35[Normokalaemic primary aldosteronism due to an aldosterone-producing adrenal adenoma--Case 06/2009]. ( Guthoff, M; Horger, M; Kirchhoff, K; Kurth, R; Müssig, K; Schnauder, G, 2009)
"A major adverse effect of these treatments is hypertension, suggesting a critical role for VEGF in blood pressure (BP) regulation."1.35Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression. ( Coffman, TM; Facemire, CS; Griffiths, R; Hurwitz, H; Nixon, AB, 2009)
"Endocrine hypertension is rare, but frequently refractory."1.35[Endocrine hypertension]. ( Ibsen, H; Poulsen, PL, 2009)
"Insulin resistance was estimated by the homeostasis model assessment."1.35Aldosterone contributes to blood pressure variance and to likelihood of hypertension in normal-weight and overweight African Americans. ( Grim, CE; Kidambi, S; Kotchen, JM; Kotchen, TA; Krishnaswami, S, 2009)
"The hypertension was not different and virtually superimposable in WT vs."1.35The role of aldosterone in mediating the dependence of angiotensin hypertension on IL-6. ( Brands, MW; Cannon, JG; Schreihofer, DA; Sturgis, LC, 2009)
"The prevalence of primary aldosteronism has increased since many patients who were previously considered as being affected by low renin essential hypertension are actually satisfying the new diagnostic criteria using plasma aldosterone/ plasma renin activity (PRA) ratio."1.35Some considerations about evolution of idiopathic primary aldosteronism. ( Armanini, D; Fiore, C, 2009)
"Hypertensive nephrosclerosis is characterized by activation of the renin-angiotensin-aldosterone system in combination with an inflammatory response characterized by an infiltration of T-cells and mononuclear cells, which release proinflammatory cytokines like IL-1beta/TNFalpha."1.35Synergistic induction of osteopontin by aldosterone and inflammatory cytokines in mesangial cells. ( Gauer, S; Geiger, H; Goppelt-Struebe, M; Hauser, IA; Holzmann, Y; Obermüller, N, 2008)
"Liddle's syndrome is an autosomal dominant form of human hypertension, caused by gain-of-function mutations of the epithelial sodium channel (ENaC) which is expressed in aldosterone target tissues including the distal colon."1.35Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome. ( Bertog, M; Cuffe, JE; Hartner, A; Hilgers, KF; Hummler, E; Korbmacher, C; Porst, M; Pradervand, S; Rossier, BC, 2008)
"Patients with primary aldosteronism were compared with patients with essential hypertension and were treated to reach a blood pressure of less than 140/90 mm Hg."1.35Cardiovascular outcomes in patients with primary aldosteronism after treatment. ( Baroselli, S; Catena, C; Chiuch, A; Colussi, G; Lapenna, R; Nadalini, E; Sechi, LA, 2008)
"The aldosterone level was comparable in both groups."1.35Diastolic dysfunction is associated with insulin resistance, but not with aldosterone level in normotensive offspring of hypertensive families. ( Poredos, P; Trojar, A; Zeljko, T; Zizek, B, 2008)
"In patients with primary aldosteronism, as a whole group, the cut-off value of 69 corresponded to the best compromise value between sensitivity (96%) and specificity (85%), with and without PRA adjustment."1.35Plasma and urine aldosterone to plasma renin activity ratio in the diagnosis of primary aldosteronism. ( Bardini, M; Bernini, G; Bernini, M; Berti, P; Miccoli, P; Moretti, A; Orlandini, C; Salvetti, A; Taurino, C, 2008)
"Aldosterone is a mineral corticoid hormone that is produced in response to angiotensin-II, and like angiotensin-II, stimulates inflammation, oxidative stress, and fibrosis by activating nuclear factor-kappaB and activating protein-1."1.35Crosstalk between the heme oxygenase system, aldosterone, and phospholipase C in hypertension. ( Jadhav, A; Lane, N; Ndisang, JF, 2008)
"ACTH-induced-hypertension is commonly employed as a model of stress-related hypertension, and despite extensive investigation, the mechanisms underlying elevated blood pressure (BP) are not well understood."1.35ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit. ( Dostanic-Larson, I; Lasko, V; Lingrel, JB; Loreaux, EL; Lorenz, JN; Paul, RJ; Schnetzer, JR, 2008)
"Primary aldosteronism (PA) is characterized by the onset of both cardiac and gluco-metabolic alterations."1.34Aldosterone as a key mediator of the cardiometabolic syndrome in primary aldosteronism: an observational study. ( Agostinelli, L; Boscaro, M; Giacchetti, G; Mantero, F; Rilli, S; Ronconi, V; Turchi, F, 2007)
"Hypertension was defined as average ambulatory blood pressure >130/85 mm Hg."1.34Association of adrenal steroids with hypertension and the metabolic syndrome in blacks. ( Grim, CE; Kidambi, S; Kotchen, JM; Kotchen, TA; Mao, J; Raff, H; Singh, RJ, 2007)
"Primary aldosteronism accompanied by hypokalemia is a cause of secondary hypertension."1.34Hypertension associated with rhabdomyolysis. ( Aslanidis, S; Douma, S; Kartali, N; Papaefthimiou, P; Petidis, K; Zamboulis, C, 2007)
"Aldosterone plays essential roles in body fluid and electrolyte homeostasis and blood pressure."1.34Polymorphism of CYP11B2 determines salt sensitivity in Japanese. ( Iwai, N; Kajimoto, K; Takashima, N; Tomoike, H, 2007)
"Essential hypertension is a disease multifactorially triggered by genetic and environmental factors."1.34Analysis of renin-angiotensin-aldosterone system gene polymorphisms in resistant hypertension. ( Barros, M; Bittencourt, I; Cabello, PH; Cordovil, IL; Dolinsky, LC; Freitas, SR; Lima, AB; Moura-Neto, RS, 2007)
"Primary aldosteronism (PA) has been considered a rare cause of hypertension."1.34Prevalence of primary aldosteronism among unselected hypertensive patients: a prospective study based on the use of an aldosterone/renin ratio above 25 as a screening test. ( Fogari, E; Fogari, R; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A, 2007)
"Primary aldosteronism (PA) represents an important cause of secondary hypertension, potentially curable, and it has been receiving particular attention due to its increasing prevalence, after the beginning of the use of plasma aldosterone concentration to plasma renin activity ratio as a screening method."1.34[Primary aldosteronism caused by aldosteronoma: problems in the etiologic diagnosis]. ( Brandão Neto, RA; Danilovic, DL; Freire, DS; Lucon, AM; Paraíba, DB; Pereira, MA, 2007)
"Treatment of primary aldosteronism decreased blood pressure (BP) and restored normal potassium concentrations."1.34Renal cysts and hypokalemia in primary aldosteronism: results of long-term follow-up after treatment. ( Baroselli, S; Bazzocchi, M; Catena, C; Chiuch, A; Colussi, GL; Lapenna, R; Nadalini, E; Novello, M; Sechi, LA, 2007)
"Aldosterone is an important cardiovascular hormone; 15% of hypertensive subjects have alteration in aldosterone regulation, defined by a raised ratio of aldosterone to renin (ARR)."1.34Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study. ( Brown, M; Caulfield, M; Clayton, D; Connell, JM; Davies, E; Dominiczak, AF; Farrall, M; Fraser, R; Freel, EM; Friel, EC; Ingram, M; Munroe, P; Samani, NJ; Webster, J, 2007)
"Primary hyperaldosteronism is not as uncommon as previously thought, but its prevalence depends on the selected population."1.34Resistant hypertension: a methodological approach to diagnosis and treatment. ( Tamimi, NA, 2007)
"Hypertension was less common in the JV than in Irbid City (9."1.34A comparative study of plasma renin activity, aldosterone and atrial natriuretic hormone between normotensive and hypertensive people living at below sea level altitude (Jordan Valley) and those residing at moderate altitude above. ( El-Migdadi, F, 2007)
"The majority of infants do not require treatment for hypertension by 6 months of age."1.34Antenatal and postnatal risk factors for neonatal hypertension and infant follow-up. ( Falk, MC; Kent, AL; Seliem, WA; Shadbolt, B, 2007)
"Primary aldosteronism (PA) is the most common secondary cause of hypertension and recently has been implicated as a cause of impaired glucose tolerance."1.34A possible association between primary aldosteronism and a lower beta-cell function. ( Artigas, RA; Carvajal, CA; Castillo, CR; Fardella, CE; Maiz, A; Mosso, LM; Ortiz, EH, 2007)
"Aldosterone excess has been reported to be a common cause of resistant hypertension."1.34Aldosterone excess and resistance to 24-h blood pressure control. ( Calhoun, DA; Cofield, SS; Gaddam, KK; Nishizaka, MK; Oparil, S; Pimenta, E; Pratt-Ubunama, MN, 2007)
"Fifty-four patients with primary aldosteronism were enrolled in a prospective study and were followed for a mean of 6."1.34Long-term cardiac effects of adrenalectomy or mineralocorticoid antagonists in patients with primary aldosteronism. ( Catena, C; Chiuch, A; Colussi, G; Gianfagna, P; Lapenna, R; Nadalini, E; Sechi, LA, 2007)
"There is a high prevalence for primary hyperaldosteronism (PHA) in hypertensive patients."1.34[Comparison of adrenal imaging and selective adrenal vein sampling in primary hyperaldosteronism]. ( Adams, S; Hahn, K; Kokulinsky, P; Liermann, D; Rump, LC; Stegbauer, J; Vonend, O, 2007)
"Thus, a reliable screening test for primary hyperaldosteronism (PA) is essential to avoid unnecessary diagnostic procedures to this population."1.34The aldosterone to renin ratio in the evaluation of patients with incidentally detected adrenal masses. ( Botoula, E; Effraimidis, G; Effremidis, G; Gavalas, N; Szabo, A; Thalassinos, NC; Tzanela, M; Valatsou, A; Vassiliadi, D, 2007)
"Primary hyperaldosteronism (PH), resulting in hypokalaemic hypertension, may be due to an aldosterone-producing adenoma (APA) or bilateral zona glomerulosa hyperplasia."1.34Prospective evaluation and characteristics of patients with suspected primary hyperaldosteronism. ( Boyne, MS; McKenzie, CA; Wright-Pascoe, R, 2007)
"Here we describe a 13-yr-old girl with primary hyperaldosteronism secondary to aldosterone-secreting adenoma."1.34An additional child case of an aldosterone-producing adenoma with an atypical presentation of peripheral paralysis due to hypokalemia. ( Acikalin, MF; Dinleyici, EC; Dogruel, N; Ilhan, H; Oztelcan, B; Tokar, B, 2007)
"Adult hypertension was induced by maternal low-protein diet during the second half of gestation."1.33Postnatal modulation of prenatally programmed hypertension by dietary Na and ACE inhibition. ( Manning, J; Vehaskari, VM, 2005)
"Recent reports suggesting that primary aldosteronism (PA) is more common than historically thought have often relied on use of the plasma aldosterone concentration (PAC) to plasma renin activity (PRA) ratio (ARR) to identify patients with PA."1.33Validity of plasma aldosterone-to-renin activity ratio in African American and white subjects with resistant hypertension. ( Calhoun, DA; Cofield, S; Nishizaka, MK; Pratt-Ubunama, M; Zaman, MA, 2005)
"Treatment with aldosterone did not modify blood pressure levels in any strain."1.33Participation of prostacyclin in endothelial dysfunction induced by aldosterone in normotensive and hypertensive rats. ( Aras-Lopez, R; Balfagón, G; Blanco-Rivero, J; Cachofeiro, V; Ferrer, M; Lahera, V; Márquez-Rodas, I; Salaices, M; Xavier, FE, 2005)
"Aldosterone plays an important role in the pathogenesis of hypertension."1.33c-Src-dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats. ( Callera, GE; He, Y; Montezano, AC; Schiffrin, EL; Tostes, RC; Touyz, RM; Yogi, A, 2005)
"Despite advances in treatment, twin-to-twin transfusion syndrome (TTTS) still carries a high risk for perinatal mortality and morbidity."1.33Paradoxic activation of the renin-angiotensin system in twin-twin transfusion syndrome: an explanation for cardiovascular disturbances in the recipient. ( Delezoide, AL; Dommergues, M; Fisk, NM; Gubler, MC; Madelenat, P; Mahieu-Caputo, D; Martinovic, J; Meulemans, A; Muller, F, 2005)
"Screening for primary hyperaldosteronism (PHA) is often indicated in individuals with resistant hypertension or hypokalaemia."1.33Prevalence of primary hyperaldosteronism in mild to moderate hypertension without hypokalaemia. ( Brown, NJ; Conlin, PR; Hopkins, PN; Jeunemaitre, X; Raji, A; Williams, GH; Williams, JS, 2006)
"Aldosterone plays a crucial role in controlling mineral balance in our body."1.33Aldosterone-induced abnormal regulation of ENaC and SGK1 in Dahl salt-sensitive rat. ( Aoi, W; Marunaka, Y; Miyazaki, H; Niisato, N; Sawabe, Y, 2006)
"A total of 25 patients with primary aldosteronism caused by Conn's adenoma, 29 patients with renovascular hypertension, and 29 patients with essential hypertension (EHT) were included in the present study."1.33Role of aldosterone in left ventricular hypertrophy in hypertension. ( Fujii, K; Iida, M; Matsumura, K; Oka, M; Oniki, H, 2006)
"Primary aldosteronism is the most common form of mineralocorticoid hypertension."1.33[Diagnosis and treatment outcome in primary aldosteronism based on a retrospective analysis of 187 cases]. ( Dabasi, G; Füto, L; Gláz, E; Horányi, J; Jakab, C; Járay, J; Kiss, R; Major, L; Molnár, F; Patócs, A; Perner, F; Rácz, K; Szücs, N; Tóth, M; Tulassay, Z; Varga, I, 2006)
"Resistant hypertension is common in clinical practice."1.33Aldosterone and refractory hypertension: a prospective cohort study. ( Calò, LA; Cattelan, F; Ciccariello, L; De Toni, R; Macchini, L; Mascagna, V; Pessina, AC; Realdi, A; Sartori, M; Semplicini, A, 2006)
"Essential hypertension is associated with changes in central catecholaminergic pathways which might also be reflected in the pituitary response to stress stimuli."1.33Decreased pituitary response to insulin-induced hypoglycaemia in young lean male patients with essential hypertension. ( Cizmarova, E; Huckova, M; Koska, J; Kvetnansky, R; Penesova, A; Radikova, Z; Vigas, M, 2006)
"Primary aldosteronism (PA) is the most frequent form of secondary hypertension, accounting for up to 5-10% of all hypertensive patients, and the diagnosis of PA can present an important challenge for the clinician."1.33Comparison of confirmatory tests for the diagnosis of primary aldosteronism. ( Fallo, F; Fardella, C; Maccario, M; Marafetti, L; Milan, A; Mosso, L; Mulatero, P; Pizzolo, F; Regolisti, G; Veglio, F, 2006)
"Primary aldosteronism has recently been recognized as the most frequent cause of secondary hypertension."1.33Confirmatory testing in normokalaemic primary aldosteronism: the value of the saline infusion test and urinary aldosterone metabolites. ( Beuschlein, F; Maser-Gluth, C; Nickel, C; Reincke, M; Rüdiger, F; Schirpenbach, C; Seiler, L, 2006)
"Aldosterone/salt-treated hypertensive rats exhibited severe proteinuria and renal injury characterized by glomerular sclerosis and tubulointerstitial fibrosis."1.33Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan. ( Abe, Y; Baba, R; Fan, YY; Fujita, M; Hosomi, N; Kimura, S; Kohno, M; Miyatake, A; Nagai, Y; Nishiyama, A; Sun, GP, 2006)
"Patients with primary aldosteronism were compared with 247 patients with essential hypertension with the same severity and duration of disease and 102 normotensive subjects."1.33Insulin sensitivity in patients with primary aldosteronism: a follow-up study. ( Baroselli, S; Catena, C; Cavarape, A; Colussi, G; Favret, G; Lapenna, R; Melis, A; Nadalini, E; Novello, M; Sechi, LA, 2006)
"Hypertension is rapidly reversible in the majority of heavy drinkers after the withdrawal of alcohol consumption."1.33Effects of alcohol withdrawal on blood pressure in hypertensive heavy drinkers. ( Basan, L; Casaccio, D; Donnini, D; Esposito, W; Isola, M; Milocco, C; Sechi, LA; Soardo, G; Soldano, F; Varutti, R, 2006)
"To search for primary hyperaldosteronism (PHA) among previously known hypertensive patients in primary care, using the aldosterone/renin ratio (ARR), and to evaluate clinical and biochemical characteristics in patients with high or normal ratio."1.33High frequency of primary hyperaldosteronism among hypertensive patients from a primary care area in Sweden. ( Bergenfelz, A; Isaksson, A; Nerbrand, C; Valdemarsson, S; Westerdahl, C; Wihl, A, 2006)
"Adenomatous primary aldosteronism (Conn's syndrome)."1.33Diagnosis of adenomatous primary aldosteronism in a patient with severe hypertension. ( Connell, JM; Freel, EM, 2005)
"Indeed, obesity hypertension has to be considered as the most common form of essential hypertension."1.33Increased aldosterone/renin quotient in obese hypertensive women: a novel role for low-density lipoproteins? ( Ansurudeen, I; Bornstein, SR; Ehrhart-Bornstein, M; Kopprasch, S; Lamounier-Zepter, V; Rotthoff, T; Scherbaum, WA, 2006)
"To screen primary aldosteronism cases with ARR (aldosterone/plasma renin activity, ARR) from patients with hypertension, and to evaluate the diagnosis value of ARR in primary aldosteronism cases and analysis the clinical characters of primary aldosteronism cases."1.33[Aldosterone/plasma renin activity ratio is a sensitive parameter for screening patients with primary aldosteronism]. ( Liu, ZJ; Shao, JM; Wang, DW; Yan, JT; Zhang, HL, 2006)
"The clinical data of 267 patients of primary hyperaldosteronism with adrenal adenoma confirmed by operation 1995 - 2005 were analyzed."1.33[Causes of delaying diagnosis of primary hyperaldosteronism with adrenal adenoma and strategy therefore]. ( Li, HZ; Pan, DL; Yan, QZ, 2006)
"Primary hyperparathyroidism was used first as a clinical model, in which hypercalcemia and normocalcemia occurs before and after surgery, respectively."1.32[Hormonal interactions of parathormone and calcium metabolism]. ( Kovács, L, 2003)
"Liddle's syndrome is a monogenic form of hypertension caused by mutations in the PY motif of the COOH terminus of beta- and gamma-epithelial Na+ channel (ENaC) subunits."1.32Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin. ( Auberson, M; Hoffmann-Pochon, N; Kellenberger, S; Schild, L; Vandewalle, A, 2003)
"The study was made in 45 patients with congestive heart failure treated in the Department of Cardiology."1.32[Cytokines and remodeling of the heart in patients with congestive heart failure]. ( Jołda-Mydłowska, B; Salomon, P, 2003)
"Left ventricular hypertrophy was present in 60% of patients."1.32The role of biochemical tests and clinical symptoms in differential diagnosis of primary aldosteronism. ( Cybulska, I; Dobrucki, T; Janas, J; Janaszek-Sitkowska, H; Januszkiewicz, A; Kabat, M; Makowiecka-Cieśla, M; Peczkowska, M; Postuła, M; Prejbisz, A, 2003)
"Overweight and obesity are frequently associated with increased plasma levels of aldosterone."1.32Human adipocytes secrete mineralocorticoid-releasing factors. ( Barthel, A; Bornstein, SR; Ehrhart-Bornstein, M; Hauner, H; Lamounier-Zepter, V; Langenbach, J; McCann, SM; Scherbaum, WA; Schraven, A; Willenberg, HS, 2003)
"Aortic dissection is a rare but severe disease."1.32[Primary aldosteronism. A risk factor for aortic dissection?]. ( Blacher, J; Kesri, L; Mourad, JJ; Safar, M; Tartière, JM, 2003)
"In glucocorticoid-remediable aldosteronism (GRA), there is a large interfamily variation of phenotype."1.32Coexistence of different phenotypes in a family with glucocorticoid-remediable aldosteronism. ( De Iasio, R; Fallo, F; Montanari, P; Morra Di Cella, S; Mulatero, P; Pilon, C; Sonino, N; Veglio, F; Williams, TA, 2004)
"Increased bioavailability of reactive oxygen species (ROS) has been implicated in the pathogenesis of mineralocorticoid hypertension."1.32NAD(P)H oxidase inhibitor prevents blood pressure elevation and cardiovascular hypertrophy in aldosterone-infused rats. ( Park, JB; Park, MY; Park, YM; Suh, YL, 2004)
"The severity of obstructive sleep apnea (OSA) correlates with the difficulty of controlling BP."1.32Aldosterone excretion among subjects with resistant hypertension and symptoms of sleep apnea. ( Calhoun, DA; Harding, SM; Nishizaka, MK; Zaman, MA, 2004)
"Obstructive sleep apnea can be detected with a careful history and various sleep studies."1.32Resistant hypertension, obesity, sleep apnea, and aldosterone: theory and therapy. ( Calhoun, DA; Goodfriend, TL, 2004)
"Primary aldosteronism (PA) is a common form of endocrine hypertension previously believed to account for less than 1% of hypertensive patients."1.32Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents. ( Fardella, CE; Gomez-Sanchez, CE; Gordon, RD; Loh, KC; Mosso, L; Mulatero, P; Stowasser, M; Veglio, F; Young, WF, 2004)
"Once considered rare, primary aldosteronism (PAL) is now regarded as the commonest potentially curable and specifically treatable form of hypertension."1.32Primary aldosteronism--careful investigation is essential and rewarding. ( Gordon, RD; Stowasser, M, 2004)
"Hyperaldosteronism was diagnosed on the basis of a renin activity <1."1.32Impaired endothelium-dependent flow-mediated vasodilation in hypertensive subjects with hyperaldosteronism. ( Calhoun, DA; Green, SA; Nishizaka, MK; Renfroe, KY; Zaman, MA, 2004)
"Primary hyperaldosteronism was not detected among the normokalemic essential hypertensives at any age using aldosterone/plasma renin activity ratio as a primary screening method."1.32Age dependence of the levels of plasma norepinephrine, aldosterone, renin activity and urinary vanillylmandelic acid in normal and essential hypertensives. ( Abd-Allah, NM; Esmat, AY; Hammad, SA; Hassan, FH, 2004)
"Primary hyperaldosteronism is a well-recognized cause of secondary hypertension."1.32Serum aldosterone and the incidence of hypertension in nonhypertensive persons. ( Benjamin, EJ; Evans, JC; Larson, MG; Levy, D; Meigs, JB; Rifai, N; Vasan, RS; Wilson, PW, 2004)
"Overweight and obesity are frequently associated with increased plasma levels of aldosterone suggesting a direct link between obesity hypertension and increased mineralocorticoid levels."1.32Fat cells may be the obesity-hypertension link: human adipogenic factors stimulate aldosterone secretion from adrenocortical cells. ( Arakelyan, K; Bornstein, SR; Ehrhart-Bornstein, M; Krug, AW; Scherbaum, WA, 2004)
"Primary aldosteronism (PA) is characterized by hypertension and suppressed renin activity with or without hypokalemia and comprises the aldosterone-producing adenoma (APA) and bilateral adrenal hyperplasia or idiopatic hyperaldosteronism (IHA)."1.32The syndromes of low-renin hypertension: "separating the wheat from the chaff". ( Biglieri, EG; Kater, CE, 2004)
"In patients with untreated hypertension, there is evidence of increased collagen synthesis, degradation, and inhibition of degradation resulting in fibrosis."1.31TIMP-1: a marker of left ventricular diastolic dysfunction and fibrosis in hypertension. ( Dunn, FG; Lindsay, MM; Maxwell, P, 2002)
"In patients with primary aldosteronism treated with spironolactone (n = 8), renin escaped suppression and reached very high levels."1.31Influence of antihypertensive medication on aldosterone and renin concentration in the differential diagnosis of essential hypertension and primary aldosteronism. ( Hahn, EG; Hensen, J; Schobel, H; Seifarth, C; Trenkel, S, 2002)
"The prevalence of primary aldosteronism (PA) was assessed in a specialized hypertension center."1.31High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives. ( Davoli, S; Negro, A; Perazzoli, F; Regolisti, G; Rossi, E; Sani, C, 2002)
"Thus aldosterone and salt treatment in uninephrectomized rats led to severe hypertension and the development of a vascular inflammatory phenotype in the heart, which may represent one mechanism by which aldosterone contributes to myocardial disease."1.31Aldosterone induces a vascular inflammatory phenotype in the rat heart. ( Blomme, EA; Delyani, JA; Frierdich, GE; Kekec, BK; McMahon, EG; Nachowiak, DA; Rocha, R; Rudolph, AE, 2002)
"Aldosterone excretion was also lower in blacks and without its normal circadian pattern which may, in part, explain their altered potassium excretion pattern."1.31Racial differences in response to acute dosing with hydrochlorothiazide. ( King, K; Ripley, E; Sica, DA, 2000)
"Hyperaldosteronism sustains much of the hypertension, but the stimuli to the increased aldosterone levels are uncertain."1.31Role of dietary potassium in the hyperaldosteronism and hypertension of the remnant kidney model. ( Hostetter, TH; Ibrahim, HN, 2000)
"Primary aldosteronism (PA) was thought to be rare but recent evidence from Australia suggests that it may be more common."1.31High prevalence of primary aldosteronism in the Tayside hypertension clinic population. ( Brennan, G; Dow, E; Jung, RT; Lim, PO; MacDonald, TM, 2000)
"A Fludrocortisone test was done to confirm the diagnosis."1.31Primary hyperaldosteronism in essential hypertensives: prevalence, biochemical profile, and molecular biology. ( Cortés, P; Fardella, CE; Foradori, A; Gómez, L; Gómez-Sánchez, C; Huete, A; Montero, J; Mosso, L; Oestreicher, E; Pinto, M; Soto, J, 2000)
"Aldosterone was unresponsive (rose by <50%) to AII in all subjects."1.31Severity of hypertension in familial hyperaldosteronism type I: relationship to gender and degree of biochemical disturbance. ( Bachmann, AW; Gordon, RD; Huggard, PR; Rossetti, TR; Stowasser, M, 2000)
"Primary aldosteronism was confirmed with the determination of PAC after 2 L saline administered iv over 4 h."1.31Prevalence of primary aldosteronism among Asian hypertensive patients in Singapore. ( Emmanuel, SC; Khaw, MC; Koay, ES; Loh, KC; Young, WF, 2000)
"Spironolactone prevented cardiac hypertrophy in adrenalectomized SHRSP."1.31Cardiac aldosterone production in genetically hypertensive rats. ( Demura, M; Mabuchi, H; Miyamori, I; Takeda, Y; Yoneda, T, 2000)
"An early diagnosis and treatment of AME syndrome could help to prevent these sequelae, and to preserve renal function."1.31Nephrocalcinosis and renal cysts associated with apparent mineralocorticoid excess syndrome. ( Jordan, SC; Kamil, ES; Moudgil, A; Rodich, G, 2000)
"A rat model of intrauterine growth retardation was employed."1.31Prenatal programming of adult hypertension in the rat. ( Aviles, DH; Manning, J; Vehaskari, VM, 2001)
"To measure the effects of hyperinsulinemia on serum electrolyte status and associated hormones, and on serum free fatty acid (FFA) concentrations, in patients with essential hypertension."1.31Serum aldosterone changes during hyperinsulinemia are correlated to body mass index and insulin sensitivity in patients with essential hypertension. ( Haenni, A; Lind, L; Lithell, H; Reneland, R, 2001)
"Gestational hypertension is a multisystem disorder which always resolves itself after delivery; its primary pathology still remains incompletely clarified."1.31The renin-aldosterone system during normal and hypertensive pregnancy. ( Creatsas, G; Elsheikh, A; Loutradis, D; Mastorakos, G; Michalas, S; Milingos, S, 2001)
"Liddle's syndrome is a rare form of hereditary hypertension caused by mutations of the epithelial sodium (Na(+)) channel (ENaC)."1.31Two sporadic cases of Liddle's syndrome caused by De novo ENaC mutations. ( Dohi, K; Enomoto, N; Hashimoto, K; Koga, M; Marumo, F; Sasaki, S; Takeda, Y; Uchida, S; Yamano, S; Yamashita, Y, 2001)
"The traditional workup for primary aldosteronism is cumbersome and requires discontinuing antihypertensive medications, which is inconvenient and potentially dangerous."1.31Screening for primary aldosteronism without discontinuing hypertensive medications: plasma aldosterone-renin ratio. ( Ahmad, S; Davidson, RC; Gallay, BJ; Toivola, B; Xu, L, 2001)
"Specific treatment of primary aldosteronism (adrenalectomy, treatment with spironolactone) led to the normalization of the BP curve with a marked BP decline."1.31Twenty-Four hour blood pressure profile in subjects with different subtypes of primary aldosteronism. ( Widimský, J; Zelinka, T, 2001)
"Primary hyperaldosteronism is more frequent among subjects with essential hypertension than previously thought."1.31[Excess of mineralocorticoids in essential hypertension: clinical-diagnostic approach]. ( Ahuad, J; Claverie, X; Cortés, P; Fardella, C; Foradori, A; Gac, H; Montero, J; Mosso, L; Oestreicher, E; Soto, J, 2000)
"Amlodipine treatment reduced the level of adrenocortical angiotensin II type 2 receptor (AT2R) mRNA in SHR from 8 weeks of age."1.31Chronic treatment with amlodipine modulates adrenocortical angiotensin II receptors in spontaneously hypertensive rats. ( Kataoka, H; Kishida, M; Makino, H; Mimura, Y; Nakamura, Y; Ogura, T; Otsuka, F; Takahashi, M; Yamauchi, T; Yokota, K, 2001)
"Liddle's syndrome is a rare form of autosomal-dominant salt-sensitive hypertension."1.31A family with liddle's syndrome caused by a mutation in the beta subunit of the epithelial sodium channel. ( Kitamura, K; Kyuma, M; Sasaki, S; Shimamoto, K; Takeuchi, H; Takizawa, H; Tomita, K; Torii, T; Ura, N, 2001)
"Hypertension was resolved at follow-up (blood pressure < 140/90 mm Hg) without use of antihypertensive agents in 31 of 93 patients (33%)."1.31Primary aldosteronism: factors associated with normalization of blood pressure after surgery. ( Farley, DR; Grant, CS; Leibson, C; Sawka, AM; Thompson, GB; van Heerden, JA; Young, WF, 2001)
"Malignant hypertension is a serious form of arterial hypertension in which the physiopathological mechanisms include increased activity of the sympathetic nervous system, renin angiotensin system, and endothelium dysfunction."1.31Hemodynamic and metabolic profile in offspring of malignant hypertensive parents. ( Bortolotto, LA; Kamitsuji, CS; Krieger, EM; Lopes, HF; Szlejf, C, 2001)
"Enrasentan-treated groups exhibited significantly improved survival (90-95% vs."1.31Enrasentan improves survival, limits left ventricular remodeling, and preserves myocardial performance in hypertensive cardiac hypertrophy and dysfunction. ( Aiyar, N; Anderson, KM; Barone, FC; Coatney, RW; Nelson, AH; Ohlstein, EH; Olzinski, AR; Willette, RN; Woods, T, 2001)
"Primary aldosteronism is a common cause of non-renal secondary hypertension."1.31Normokalemic hyperaldosteronism in patients with resistant hypertension. ( Benchetrit, S; Bernheim, J; Podjarny, E, 2002)
" Losartan improved the shifted circadian BP rhythm towards the active phase in a dose-dependent manner, whereas the improvement caused by 1 and 3 mg/day of benazepril was less effective than the same dosage of losartan."1.31Effects of losartan and benazepril on abnormal circadian blood pressure rhythm and target organ damage in SHRSP. ( Hayasaki-Kajiwara, Y; Iwasaki, T; Nakajima, M; Naya, N; Shimamura, T, 2002)
"1."1.31Is primary aldosteronism underdiagnosed in clinical practice? ( Bobrie, G; Fiquet-Kempf, B; Launay-Mignot, P; Plouin, PF, 2001)
"Since primary aldosteronism has been reported in asymptomatic incidental adrenal masses (adrenal incidentalomas, AI), the aim of our study was to detect primary aldosteronism in normokalemic patients with AI and to verify whether a raised plasma aldosterone (ALD)/plasma renin activity (PRA) ratio may be useful for diagnosis."1.31Primary aldosteronism in normokalemic patients with adrenal incidentalomas. ( Argenio, G; Bernini, G; Moretti, A; Salvetti, A, 2002)
"In 92 patients with chronically treated essential hypertension, two-dimensional and Doppler echocardiographic examinations were performed and LV inflow velocities were measured for evaluation of LV diastolic function."1.31Influence of plasma aldosterone on left ventricular geometry and diastolic function in treated essential hypertension. ( Horio, T; Iwashima, Y; Kawano, Y; Kuroda, S; Takishita, S, 2002)
"Also, 17 patients with known primary aldosteronism were retrospectively examined."1.31Ratio of serum aldosterone to plasma renin concentration in essential hypertension and primary aldosteronism. ( Hahn, EG; Hensen, J; Schobel, H; Seifarth, C; Trenkel, S, 2002)
"Aldosterone levels were significantly reduced by all treatments."1.31Combination of non-hypotensive doses of valsartan and enalapril improves survival of spontaneously hypertensive rats with endothelial dysfunction. ( Bruneval, P; Clozel, JP; de Gasparo, M; Hess, P; Nuesslein-Hildesheim, B, 2000)
"Primary aldosteronism is a disorder that is commonly considered in patients referred to the hypertension clinic."1.31Unilateral adrenal hyperplasia causing primary aldosteronism: limitations of I-131 norcholesterol scanning. ( Arici, MH; Karimeddini, MK; Malchoff, CD; Mansoor, GA; Whalen, GF, 2002)
"Since hypertension affects a considerable proportion of obese patients, circulating RAAS has been studied in obese subjects with and without hypertension, albeit with conflicting results."1.31Comparison of circulating and local adipose tissue renin-angiotensin system in normotensive and hypertensive obese subjects. ( Camilloni, MA; Faloia, E; Garrapa, GG; Gatti, C; Giacchetti, G; Mantero, F; Mariniello, B; Sardu, C, 2002)
"Hyperaldosteronism has been causally linked to myocardial interstitial fibrosis experimentally, but it remains unclear if this link also applies to humans."1.31Excess aldosterone is associated with alterations of myocardial texture in primary aldosteronism. ( Bertini, A; Cesari, M; Di Bello, V; Ganzaroli, C; Giorgi, D; Mariani, M; Pessina, AC; Rossi, GP; Sacchetto, A; Scognamiglio, R, 2002)
"The triamterene therapy was effective in correcting the endocrine and metabolic disorders as well as arterial hypertension, but did not prevent a deficit in mental and physical development."1.30Liddle's syndrome: a 14-year follow-up of the youngest diagnosed case. ( Capodaglio, PF; Cugini, P; Mazzeo, D; Tucciarone, L; Vania, A, 1997)
"Men with left ventricular hypertrophy presented with significantly higher serum ACE concentrations than those with normal left ventricular mass index (P = 0."1.30Associations between circulating components of the renin-angiotensin-aldosterone system and left ventricular mass. ( Danser, AH; Hense, HW; Kürzinger, S; Luchner, A; Muscholl, M; Riegger, GA; Schunkert, H, 1997)
"In primary aldosteronism, protein kinase C and calmodulin seem to have synergistic stimulatory effects on red blood cell Na(+)-H+ exchange, and both increase the affinity of the exchanger to H+, while their effect on Na+ binding is opposite."1.30Increased Na(+)-H+ exchange in red blood cells of patients with primary aldosteronism. ( Koren, W; Postnov, IY; Postnov, YV, 1997)
"In contrast, left ventricular hypertrophy markedly progressed despite the mild extracardiac target-organ damage in primary aldosteronism."1.30Left ventricular hypertrophy precedes other target-organ damage in primary aldosteronism. ( Hamada, M; Hara, Y; Hayashi, Y; Hiwada, K; Kodama, K; Kohara, K; Okayama, H; Shigematsu, Y, 1997)
"Aldosterone treatment of vascular smooth muscle cells cultured from WF resulted in 82% less upregulation of angiotensin II radioligand binding, 50% less induction of angiotensin II AT1a receptor mRNA, and 76% less potentiation of angiotensin II-stimulated inositol phosphates than did aldosterone treatment of cells from W."1.30Resistance to mineralocorticoids in Wistar-Furth rats. ( Fitzgibbon, WR; Islam, MM; Paul, RV; Robinson, CJ; Tobin, ET; Ullian, ME, 1997)
"Liddle's syndrome is an autosomal dominant form of hypertension that resembles primary hyperaldosteronism, is characterized by the early onset of hypertension with hypokalemia and suppression of both PRA and aldosterone, and is caused by mutations in the carboxyl-terminus of the beta- or gamma-subunits of the renal epithelial sodium channel."1.30Liddle's syndrome: prospective genetic screening and suppressed aldosterone secretion in an extended kindred. ( Findling, JW; Hansson, JH; Lifton, RP; Raff, H, 1997)
"Since hyperaldosteronism has been experimentally related to myocardial interstitial fibrosis, we investigated the effects of hypertension and excess aldosterone due to aldosterone-producing adenomas (APAs) on the heart."1.30Remodeling of the left ventricle in primary aldosteronism due to Conn's adenoma. ( Canali, C; Graniero, GR; Palatini, P; Pavan, E; Pessina, AC; Rossi, GP; Sacchetto, A, 1997)
"A case of primary hyperaldosteronism and cardiomegaly due to a unilateral adrenal adenoma in a newborn is presented."1.30Hypertensive cardiomegaly caused by an aldosterone-secreting adenoma in a newborn. ( Armanini, D; Cecchetto, G; Fassina, A; Opocher, G; Pozzan, GB; Rigon, F; Zacchello, F, 1997)
"The results suggest that left ventricular hypertrophy is more pronounced in patients with primary aldosteronism than in patients with other forms of hypertension."1.30Left ventricular hypertrophy is more prominent in patients with primary aldosteronism than in patients with other types of secondary hypertension. ( Demura, H; Demura, R; Hase, M; Naruse, K; Naruse, M; Seki, T; Tanabe, A; Tanaka, M; Yoshimoto, T, 1997)
"We evaluated the renal hemodynamic status of 19 hypertensive patients with NIDDM under controlled sodium balance, low (10 mmol/day for 5 to 7 days) or high (200 mmol/day for 5 to 7 days)."1.30Autonomy of the renin system in type II diabetes mellitus: dietary sodium and renal hemodynamic responses to ACE inhibition. ( Allan, DR; De'Oliveira, JM; Fisher, ND; Hollenberg, NK; McKnight, JA; Price, DA; Williams, GH, 1997)
"Glucocorticoid-remediable aldosteronism (GRA) is a rare form of inherited hypertension caused by a characteristic gene duplication."1.30Evaluation of the dexamethasone suppression test for the diagnosis of glucocorticoid-remediable aldosteronism. ( Coolidge, C; Dluhy, RG; Lifton, RP; Litchfield, WR; New, MI, 1997)
"The syndrome is characterised by sodium retention and hypervolemia despite low plasma renin activity and aldosterone levels."1.30[A case of apparent mineralocorticoid excess caused by type 2 11 beta- hydroxysteroid dehydrogenase deficiency]. ( Caillette, A; Corvol, P; Fiet, J; Krozowski, Z; Marc, JM; Morineau, G; Pascoe, L, 1997)
" A dose-response curve to acetylcholine was performed at cumulative concentrations from 10(-9) to 10(-5) mol/L."1.30Endothelial dysfunction in hypertension is independent from the etiology and from vascular structure. ( Agabiti-Rosei, E; Bernini, G; Bettoni, G; Castellano, M; Giulini, SM; Muiesan, ML; Porteri, E; Rizzoni, D; Rossi, G; Tiberio, G, 1998)
"L-NAME treatment induced hypertension that was associated with increased plasma renin activity."1.30Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo. ( Brosnan, MJ; Devlin, AM; Dominiczak, AF; Graham, D; Hamilton, CA; McIntyre, M; McPhaden, AR; Morton, JJ; Reid, JL, 1998)
"Aldosterone levels during treatment [13."1.30Evidence for persistent dysfunction of wild-type aldosterone synthase gene in glucocorticoid-treated familial hyperaldosteronism type I. ( Gartside, MG; Gordon, RD; Stowasser, M; Taylor, WL; Tunny, TJ, 1997)
"RFR was examined in 33 IDDM patients in similar glycaemic and metabolic control and compared to 12 healthy control subjects, during eight 1 h clearance periods prior to, during and after a 3-h stimulation by amino acid infusion (4."1.30Renal functional reserve in IDDM patients. ( Ader, JL; Hanaire-Broutin, H; Sackmann, H; Tack, I; Tauber, JP; Tran-Van, T, 1998)
"Hypertension is a common multifactorial disorder associated with considerable morbidity and mortality."1.30The diagnosis of Liddle syndrome by identification of a mutation in the beta subunit of the epithelial sodium channel. ( Houtman, P; Jackson, SN; Trembath, RC; Williams, B, 1998)
"In conclusion, primary aldosteronism is characterized by decreased supine and standing BP variability, which is due in part to the preservation of baroreflex function."1.30Decreased blood pressure variability at rest in patients with primary aldosteronism. ( Abe, K; Aihara, A; Imai, Y; Munakata, M; Yoshinaga, K, 1998)
"As insulin resistance has been suggested as the unifying factor in the insulin resistance metabolic syndrome, insulin resistance was evaluated by the euglycaemic hyperinsulinaemic clamp technique in 50 untreated hypertensive subjects in whom PRA and serum aldosterone were measured together with lipids and an intravenous glucose tolerance test (IVGTT)."1.30Insulin resistance in essential hypertension is related to plasma renin activity. ( Andersson, PE; Haenni, A; Lind, L; Lithell, H; Reneland, R, 1998)
"Aldosterone-salt treatment induced, (1) arterial hypertension (+40%) and LV hypertrophy (+60%) without altering LV-fractional shortening, (2) an increase in plasma norepinephrine levels (+262%) and suppression of renin activity."1.30Modifications of myocardial Na+,K(+)-ATPase isoforms and Na+/Ca2+ exchanger in aldosterone/salt-induced hypertension in guinea pigs. ( Carayon, A; Charlemagne, D; Lechat, P; Mougenot, N; Ramírez-Gil, JF; Trouvé, P, 1998)
"Cardiac fibrosis is linked to aldosterone-induced hypertension, but the effects on in vivo left ventricular (LV) function are not established."1.30In vivo left ventricular function and collagen expression in aldosterone/salt-induced hypertension. ( Charlemagne, D; Delcayre, C; Lechat, P; Mougenot, N; Ramirez-Gil, JF; Robert, V; Trouve, P; Wassef, M, 1998)
"Twenty-three patients with primary aldosteronism, 22 essential hypertensive patients and 16 normal controls were studied."1.30Impaired baroreflex function and arterial compliance in primary aldosteronism. ( Cat Genova, G; Chiandussi, L; Grosso, T; Martini, G; Melchio, R; Molino, P; Rabbia, F; Veglio, F, 1999)
"Low-renin hypertension is characterized by a high ratio of aldosterone to plasma renin activity (ALD/PRA), which may suggest inappropriately increased aldosterone biosynthesis."1.30Genetic polymorphism of CYP11B2 gene and hypertension in Japanese. ( Iwai, N; Kinoshita, M; Tamaki, S; Tsujita, Y, 1999)
"Because essential hypertension is partly genetic, it is possible that altered control of aldosterone synthase gene expression or translation may be responsible."1.30Aldosterone excretion rate and blood pressure in essential hypertension are related to polymorphic differences in the aldosterone synthase gene CYP11B2. ( Anderson, NH; Connell, JM; Davies, E; Fraser, R; Friel, EC; Holloway, CD; Inglis, GC; Ingram, MC; Morrison, C, 1999)
"Patients with newly discovered, never-treated, sustained hypertension were included in the study after a 1 month run-in, during which time their blood pressure was measured three times at 2 week intervals."1.30Clinic-daytime blood pressure difference and cardiovascular damage. ( Celentano, A; Crivaro, M; Ferrara, LA; Gaeta, I; Guida, L; Iannuzzi, R; Marotta, T; Pasanisi, F, 1999)
"Normotensive primary hyperaldosteronism is exceedingly rare."1.30Aldosterone-producing adenoma without hypertension: a report of two cases. ( Ghulam, A; Jeunemaitre, X; Lefebvre, J; Provost, F; Ronci, N; Tabarin, A; Vantyghem, MC, 1999)
"To study severity of left ventricular hypertrophy (LVH) and left ventricular function in patients with primary aldosteronism (PA) in comparison with hyperaldosteronemia and preoperative arterial hypertension, to follow the dynamics of these parameters early and late after surgical removal of aldosteroma."1.30[Left ventricular myocardial structure and function in patients with primary aldosteronism]. ( Arabidze, GG; Chikhladze, NM; Iarovaia, EB; Sergakova, LM, 1999)
"Treatment with amiloride was effective."1.30[Mineralocorticoid-like hypertension. "Apparent mineralocorticoid excess". A hereditary type of hypertension?]. ( Christensen, TH; Ibsen, H; Kaae, HH, 1999)
"Neurofibromatosis type 1 is a phacomatosis."1.30A case of neurofibromatosis type 1 with an aldosterone-producing adenoma of the adrenal. ( Alessandri, M; Biagi, P; Campanella, G; Castro, R; Fanciullacci, M; Totteri, A, 1999)
"Animal models for preeclampsia are no alternative to clinical studies, but they are furthering our understanding of pathophysiology in many fields."1.30[Animal experiment models of hypertension in pregnancy--an alternative to clinical studies?]. ( Casper, F; Hropot, M; Leiser, R; Seufert, R, 1999)
"Primary hyperaldosteronism is more frequent than previously thought, it is overlooked when hypokalemia is used as the screening test and it can only be diagnosed measuring plasma aldosterone and renin activity."1.30[High prevalence of undiagnosed primary hyperaldosteronism among patients with essential hypertension]. ( Fardella, C; Foradori, A; Huete, A; Montero, J; Mosso, L; Rojas, A; Rojas, P; Rojas, V; Sánchez, O; Soto, J, 1999)
"Aldosterone-renin ratio was in PH patients 10-fold higher comparing with EH patients."1.30[Incidence of primary hyperaldosteronism in hospitalized patients with hypertension]. ( Bober, J; Lazurova, I; Schwartz, P; Sokol, L; Trejbal, D; Trejbalova, L; Valansky, L; Wagnerova, H; Zachar, M, 1999)
"Primary aldosteronism comprises two different conditions, the tumoral form usually caused by an adenoma and the idiopathic form due to nodular hyperplasia of the two adenals."1.29[Conceptual basis and diagnosis of primary hyperaldosteronism]. ( Amar, J; Begasse, F; Chamontin, B; Guittard, J; Salvador, M, 1995)
"Dexamethasone-sensitive hyperaldosteronism is associated with early onset hypertension and primary hyperaldosteronism."1.29[Hyperaldosteronism sensitive to dexamethasone with adrenal adenoma. Clinical, biological and genetic study]. ( Aupetit-Faisant, B; Charru, A; Corvol, P; Guyene, TT; Jeunemaitre, X; Pascoe, L; Plouin, PF; Schambelan, M; Shackleton, CH, 1995)
" Co-administration with propranolol markedly decreased the heart rate, but little affected the heart weight, suggesting changes in the heart rate during the long-term administration of KW-3049 did not largely affect cardiac hypertrophy."1.29Effect of the new calcium antagonist (+/-)-(R*)-3-[(R*)-1-benzyl-3- piperidyl] methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5- pyridinedicarboxylate hydrochloride (KW-3049) on cardiac hypertrophy in spontaneously hypertensive rats. ( Deguchi, T; Hara, T; Hattori, O; Kato, Y; Saijyo, T; Suzuki, K; Tanaka, H, 1993)
" In summary, during long-term administration of L-NAME, progressive increases in BP levels were observed without changes in either sodium excretion or enhanced circulating vasoconstrictor activity."1.29Hormonal, renal, and metabolic alterations during hypertension induced by chronic inhibition of NO in rats. ( García-Estań, J; Lahera, V; Moncada, S; Navarro, J; Romero, JC; Ruilope, LM; Sáiz, J; Sanchez, A, 1994)
"The degree of hyperaldosteronism in the subjects was mild compared with other conditions and, although an effect on left ventricular mass index could be detected, the present results indicate that other factors may be necessary for the development of left ventricular hypertrophy."1.29Left ventricular mass in hereditary human hypertension: glucocorticoid-suppressible hyperaldosteronism. ( Connell, JM; Jamieson, A; Kennedy, JA; Murdoch, D, 1995)
"Preeclampsia is accompanied by amplification of the sodium retention that is a feature of normal pregnancy."1.2911 beta-Hydroxysteroid dehydrogenase and its inhibitors in hypertensive pregnancy. ( Brown, MA; Edwards, CR; Honour, JW; Walker, BR; Whitworth, JA; Williamson, PM, 1995)
"Nephrocalcinosis was still present 8 years later and hypertension was recurring obviously as a consequence of increased peripheral resistance."1.29Aldosterone and testosterone producing adrenal adenoma in childhood. ( Burda, G; Frisch, H; Neuhold, N; Schmitt, K; Schober, E, 1995)
"01) with chronic administration of propranolol, suggesting a reflection of decreased cardiac function."1.29Atrial natriuretic peptide and antihypertensive action due to beta-blockade in essential hypertensive patients. ( Hama, J; Horiuchi, M; Kamoi, K; Katori, R; Kino, H; Nagata, S; Shimada, S; Takenaka, T, 1995)
"In patients with primary aldosteronism and renovascular hypertension the plasma aldosterone level was shown to be an important factor upregulating AT1 receptor mRNA."1.29Angiotensin II type 1 receptor messenger RNA levels in human blood cells of patients with primary and secondary hypertension: reference to renin profile. ( Murakami, M; Saruta, T; Sato, A; Shibata, H; Suzuki, H, 1994)
"Primary aldosteronism caused by an aldosterone-producing adrenal adenoma was documented in an 11-year-old girl who presented with persistent hypertension, headache, tinnitus and hypokalemia."1.29Adrenal adenoma with primary aldosteronism in a child: a case report. ( Chang, WT; Chen, HC; Lai, FC; Peng, HC; Wen, MC, 1994)
"Spironolactone treatment (50 mg/kg per day) for 7 days in deficient rats restored blood pressure and heart rate to normal levels and significantly reduced sodium levels in erythrocytes and cerebrospinal fluid."1.29Hypertension induced by a nonpressor dose of angiotensin II in kininogen-deficient rats. ( Katori, M; Kuribayashi, Y; Majima, M; Mizogami, S; Oh-ishi, S, 1994)
"Arterial hypertension is nowadays no longer considered an isolated disorder of blood pressure regulation but a multifactorial disease with metabolic and cellular deviations."1.29[Changes in humoral pressor and depressor factors in essential hypertension during lisinopril therapy]. ( Horký, K; Jáchymová, M; Jarolím, M; Jindra, A; Kolár, J; Peleska, J; Savlíková, J; Stolba, P; Umnerová, V; Vorlová, Z, 1994)
"Spironolactone treatment (100 mg/daily) completely reversed the syndrome of mineralocorticoid excess."1.29Unilateral adrenal hypersecretion of both aldosterone and cortisol in two first cousins with a syndrome of mineralocorticoid excess but without signs of hypercortisolism. ( Balsano, F; Bonavita, MS; Carlomagno, A; Coassin, S; De Siati, L; Falaschi, P; Ferri, C; Gualdi, G, 1994)
" The hypotensive action of NZ-105 were reproducible after repeated dosing for 12 weeks."1.29Effects of long-term oral administration of NZ-105, a novel calcium antagonist, with or without propranolol in spontaneously hypertensive rats. ( Kasuya, Y; Masuda, Y; Sakai, T; Shigenobu, K; Shudo, C; Tanaka, S, 1993)
"1."1.29Acute sodium loading in patients with uncomplicated diabetes mellitus: renal and hormonal effects. ( Beretta-Piccoli, C; Cusi, D; Elshater-Zanetti, F; Shaw, S; Weidmann, P, 1994)
"From these data it emerges that hyperaldosteronism, as observed in these patients with CRI, is a relatively reliable marker of the extent of CRI and may occur independently of the activation of the RAA system, given that other factors, such as orthostatic stimulation, alterations in the acid-base equilibrium, and the degree of aldosterone hepatic and urinary clearance, contribute to its pathogenesis."1.29[Role of aldosterone in essential arterial hypertension complicated by chronic renal insufficiency]. ( Buracchi, P; Carletti, F; Gennari, C; Lucani, B; Martinelli, M; Nami, R; Panza, F; Pavese, G; Saia, F, 1993)
"The hyperaldosteronism could not be suppressed by dexamethasone."1.29[Unilateral autonomous aldosterone production in hyperaldosteronism suppressible by dexamethasone]. ( Haack, D; Jakob, F; Ludwig, J; Rendl, J; Schröder, K; Seufert, J; Vecsei, P, 1993)
"The reactive fibrosis is thought to be related to MC excess, while cell loss and microscopic scarring may be secondary to enhanced potassium excretion or a cytotoxic effect of aldosterone."1.29Myocardial fibrosis in the rat with mineralocorticoid excess. Prevention of scarring by amiloride. ( Campbell, SE; Janicki, JS; Matsubara, BB; Weber, KT, 1993)
"Effective management of primary aldosteronism is dependent upon correct localization of excessive aldosterone production."1.29Evaluation of diagnostic tests in the differential diagnosis of primary aldosteronism: unilateral adenoma versus bilateral micronodular hyperplasia. ( Bihrle, R; Donohue, JP; Dugan, J; Eller, D; Gleason, PE; Pratt, JH; Weinberger, MH, 1993)
"Spironolactone, however, was able to prevent myocardial fibrosis in RHT and aldosterone models of acquired arterial hypertension irrespective of the development of LVH and the presence of hypertension."1.29Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension. ( Brilla, CG; Matsubara, LS; Weber, KT, 1993)
"As our model we selected type 1 diabetes with peripheral circulatory hyperinsulinemia induced by sc insulin treatment."1.29Nocturnal blood pressure elevation is related to adrenomedullary hyperactivity, but not to hyperinsulinemia, in nonobese normoalbuminuric type 1 diabetes. ( Gromeier, S; Kerner, W; Kohlmann, T; Look, D; Peters, A, 1996)
"Primary aldosteronism (PA) is caused by an adrenal aldosterone-producing tumor (A-APT) or adrenal hyperplasia."1.29Prevalence of adrenal and extra-adrenal Conn syndrome in hypertensive patients. ( Abdelhamid, S; Bönhof, JA; Müller-Lobeck, H; Pahl, S; Remberger, K; Röckel, A; Walb, D, 1996)
"Although primary hyperaldosteronism is an uncommon cause of hypertension, it is the most common form of renin-independent hypermineralocorticoidism."1.29[Adrenal adenoma or hyperplasia? Problems of differential diagnosis in an unusual case of primary hyperaldosteronism]. ( Bonifacio, V; Ciampani, T; Giannini, D; Mancini, G; Sanna, AL, 1996)
"It has been recognised recently that primary hyperaldosteronism may be more common than previously thought, the frequency of diagnosis being improved by screening using a plasma aldosterone concentration to renin activity ratio."1.29Primary hyperaldosteronism: a missed diagnosis in 'essential hypertensives'? ( Brown, MA; Cramp, HA; Whitworth, JA; Zammit, VC, 1996)
"Aldosterone was unresponsive (<50% rise) to 2 h of upright posture following overnight recumbency in 15 out of 15 (100%) patients studied, and to angiotensin II infusion (2 ng/kg per min for 1 h) in 14 out of 14 patients (100%)."1.29Clinical, biochemical and genetic approaches to the detection of familial hyperaldosteronism type I. ( Bachmann, AW; Gordon, RD; Jonsson, JR; Klemm, SA; Stowasser, M; Tunny, TJ, 1995)
"The patients with primary aldosteronism had lower serum potassium and higher plasma aldosterone concentrations than those with essential hypertension."1.29Albuminuria in untreated patients with primary aldosteronism or essential hypertension. ( Halimi, JM; Mimran, A, 1995)
"In control subjects and patients with Conn's syndrome, the DOC:B ratio was not affected by ACTH."1.2911 beta-Hydroxylase activity in glucocorticoid suppressible hyperaldosteronism: lessons for essential hypertension? ( Connell, JM; Davies, E; Fraser, R; Ingram, M; Jamieson, AJ; Soro, A, 1996)
"Nilvadipine appears to be an effective hypotensive agent at single daily doses of 8 mg."1.28Nilvadipine in hypertension with renal dysfunction. ( Albert, FW; Berger, HH, 1992)
"Liddle's syndrome (or pseudoprimary aldosteronism) is a rare hereditary disease; only 18 cases have been reported since 1963."1.28[Liddle syndrome (or pseudo-hyperaldosteronism). Long-term development and erythrocyte potassium flow study in 4 cases]. ( Charpentier, B; Dommergues, JP; Fries, D; Garay, RP; Guillot, M; Jullien, M; Kleinknecht, D; Nazaret, C; Noblins, M, 1992)
"ANP, aldosterone and renin were examined during natriuresis of fasting in 25 obese essential hypertensive patients and nine overweight normotensive subjects placed on a supervised 500-KCal diet composed of 50% carbohydrates, 30% fat and 20% protein, and unlimited salt."1.28The role of atrial natriuretic peptide in natriuresis of fasting. ( Maoz, E; Peleg, E; Rosenthal, T; Salzberg, M; Shamiss, A, 1992)
" Therefore, after 4 weeks of washout with placebo (phase 1), doxazosin (dosage range from 1 to 16 mg, plus hydrochlorothiazide when necessary) was given to 11 essential hypertensive patients (6 M, 5 F, age range 34-63 years) for 8 weeks (phase 2) in order to achieve diastolic blood pressure values less than 90 mmHg; this dosage was then maintained for a further 20 weeks up to the end of the study (phase 3)."1.28Reduction of left ventricular hypertrophy after longterm antihypertensive treatment with doxazosin. ( Agabiti-Rosei, E; Beschi, M; Calebich, S; Castellano, M; Muiesan, G; Muiesan, ML; Rizzoni, D; Zulli, R, 1992)
"Aldosterone-producing adenomas (Conn's syndrome) are also commonly composed of zona fasciculata-like cells, make "hybrid steroids" in excess and are very sensitive to ACTH but not to angiotensin II."1.28Primary aldosteronism: hypertension with a genetic basis. ( Gordon, RD; Klemm, SA; Stowasser, M; Tunny, TJ, 1992)
"Hence, cardiac hypertrophy during chronic exposure to cold is supported by other factors, possibly by the increased concentration of either norepinephrine or triiodothyronine, or both, which occurs characteristically in rats under these conditions."1.28Effect of a reduction in sodium intake on cold-induced elevation of blood pressure in the rat. ( Fregly, MJ; Papanek, PE; van Bergen, P, 1992)
"In patients with MPGN, the levels of total renin (TR) and inactive renin (IR) were significantly higher than in those suffering from MSPGN."1.28[The morphofunctional parallels in arterial hypertension in patients with chronic glomerulonephritis]. ( Degtereva, OA; Gadaev, A; Kaiukov, IG; Kotovoĭ, IuO; Kucher, AG; Riabov, SI, 1992)
"Thromboxane A2 has opposite effects."1.28Renin-angiotensin-aldosterone system and thromboxane A2/prostacyclin in normotensive and hypertensive black Zimbabweans. ( Mufunda, JJ; Somova, LI, 1992)
"3."1.28Concurrence of primary aldosteronism and renal artery stenosis. ( Gordon, RD; Grunstein, H; Monaghan, JC; Roche, J; Stokes, GS, 1992)
"Aldosterone was analyzed by radioimmunoassay and [4-14C]aldosterone radiometabolites by high-performance liquid chromatography."1.28Aldosterone metabolism in the isolated perfused liver of R and S hypertension-prone Dahl rats. ( Egfjord, M; Olgaard, K, 1992)
"Aldosterone-salt treatment produced decreased vascular sensitivity to acetylcholine and nitroprusside in both Wistar and Wistar-Furth rats."1.28Vascular responsiveness in rats resistant to aldosterone-salt hypertension. ( Bruner, CA, 1992)
"Aldosterone was increased in the SHR-S strain compared with the SHR-R strain on the low NaCl diet, but aldosterone was not different between the two strains on the high NaCl diet."1.28Adrenocorticosteroid excretion in salt-sensitive and salt-resistant spontaneously hypertensive rats. ( Griffing, GT; Holbrook, M; Melby, JC; Wilson, TC; Wyss, MJ, 1992)
"Captopril treatment should be introduced carefully since not all those patients at risk of hypotension can be identified in advance."1.28First dose hypotension after captopril; can it be predicted? A study of 240 patients. ( de Boo, T; Dennesen, PJ; Postma, CT; Thien, T, 1992)
"Nitrendipine is a calcium antagonist of the dihydropiridine group that may be given once daily."1.28Regression of cardiovascular structural changes after long-term antihypertensive treatment with the calcium antagonist nitrendipine. ( Agabiti-Rosei, E; Beschi, M; Castellano, M; Muiesan, ML; Rizzoni, D; Romanelli, G, 1991)
" Chronic administration of spironolactone prevented the development of hypertension but failed to prevent other adaptive physiological changes characteristically occurring during exposure to cold and seen in the cold-treated control rats."1.28Effect of chronic treatment with clonidine and spironolactone on cold-induced elevation of blood pressure. ( Baron, A; Fregly, MJ; Riesselmann, A, 1991)
"A peculiar form of hyperaldosteronism is the glucocorticoid-remediable subtype."1.28New aspects of mineralocorticoid hypertension. ( Armanini, D; Biason, A; Boscaro, M; Carpenè, G; Fallo, F; Mantero, F; Opocher, G; Rocco, S; Scaroni, C; Sonino, N, 1990)
" HPC-EC10 (5:3) microcapsules containing piretanide were satisfactory as a sustained-release preparation in the light of the anti hypertensive effect even at a half frequency of daily dosing of the solution."1.28Pharmacological evaluation of hydroxypropylcellulose-ethylcellulose microcapsules containing piretanide. ( Goto, S; Kawata, M; Kuriki, T; Suzuki, N; Tsujiyama, T, 1990)
"Essential hypertension is not a pathophysiologically homogenous disease with respect to reactivity and interaction of plasma catecholamines and PRA."1.28Relationship between plasma catecholamines and the renin-aldosterone system during exercise in normal and essential hypertensive subjects. ( Bultas, J; Jindra, A; Savliková, J, 1990)
"In conclusion, hypertension is a common problem in acromegaly and at least in part related to similar risk factors in control populations."1.28Acromegaly and hypertension: prevalence and relationship to the renin-angiotensin-aldosterone system. ( Benker, G; Hirche, H; Kraatz, C; Lüdecke, D; Reinwein, D; Weber, F, 1990)
"Aldosterone was preferentially metabolized to THA in LRH."1.28Alterations in aldosterone secretion and metabolism in low renin hypertension. ( Griffing, GT; Melby, JC; Wilson, TE, 1990)
"Aldosterone treatment resulted in an increase in blood pressure to 165 +/- 5 mmHg over the control value of 105 +/- 2 mmHg within 3 wk of experimental period."1.28Effects of antimineralocorticoid RU 26752 on steroid-induced hypertension in rats. ( Agarwal, M; Corley, K; Kalimi, M; Opoku, J, 1990)
"Nonmodulating hypertension is characterized, in part, by a decreased aldosterone response to AII, raising the possibility that an increased dopaminergic inhibition of aldosterone secretion underlies the adrenal defect in nonmodulating hypertension."1.28Dopamine and nonmodulating hypertension. ( Conlin, PR; Gordon, MS; Hollenberg, NK; Stuenkel, CA; Williams, GH, 1990)
" The purpose of the present study was to examine whether long-term therapy with ramipril (RA, and ACE inhibitor) would lower blood pressure more effectively and without adverse reactions in combination with the loop diuretics piretanide (PI) or furosemide (FU)."1.28Loop diuretics combined with an ACE inhibitor for treatment of hypertension: a study with furosemide, piretanide, and ramipril in spontaneously hypertensive rats. ( Baldes, L; Becker, RH; Treudler, M, 1989)
"1."1.28Endogenous digoxin-like immunoreactive factor and digitalis-like factor associated with the hypertension of patients receiving multiple alkylating agents as part of autologous bone marrow transplantation. ( Antman, KH; Brena, A; Eder, JP; Graves, SW; Peters, WP; Schryber, SM; Sharma, K, 1989)
"Bopindolol was given to hypertensive patients in a single daily dose ranging from 1 to 4 mg."1.28Bopindolol: long-term effects on blood pressure, renal function, plasma renin activity, and plasma aldosterone in mild-to-moderate essential hypertension. ( Modan, M; Rosenfeld, JB; Shohat, J, 1989)
"Aldosterone levels were most strongly related inversely to duration of diabetes, diabetic retinopathy, parasympathetic neuropathy and directly to diastolic blood pressure and glomerular filtration rate."1.28Relationships between renin, aldosterone, blood pressure and renal function in hypertensive insulin-dependent diabetes mellitus. ( Baker, R; Waldek, S; Winocour, PH, 1989)
"Postoperatively the signs of hyperaldosteronism (Conn's syndrome) regressed and the average blood pressure was 112/76 mm Hg."1.28[Primary hyperaldosteronism without arterial hypertension]. ( Andrassy, K; Buhr, H; Osterziel, KJ; Raue, F; Vecsei, P; Zeier, M; Ziegler, R, 1989)
"The pharmacokinetic parameters of unchanged plasma captopril and the kinetics of the drug effects on plasma converting enzyme activity (PCEA), plasma renin activity (PRA), plasma aldosterone (PA) and mean blood pressure (MBP) were studied over 24 h after oral administration in three groups of hypertensive patients: with normal renal function (group 1, plasma creatinine less than 110 mumol/l, n = 10), with moderate chronic renal failure (group 2, 135 less than plasma creatinine less than 450 mumol/l, n = 10) and with severe chronic renal failure (group 3, plasma creatinine greater than 500 mumol/l, n = 10)."1.27Influence of chronic renal failure on captopril pharmacokinetics and clinical and biological effects in hypertensive patients. ( Chaignon, M; Giroux, B; Giudicelli, JF; Guedon, J; Richer, C, 1984)
"Minoxidil was used in 48 patients with AH of varying clinical forms, 19 of those having the malignant AH syndrome."1.27[Use of angiotensin converting enzyme inhibitor captopril and peripheral vasodilator minoxidil in the treatment of patients with stable and malignant arterial hypertension]. ( Arabidze, GG; Kutsenko, AI; Leshchinskiĭ, PM; Lordkipanidze, NL; Masenko, VP, 1983)
"Although secondary hyperaldosteronism due to renal vein thrombosis may occur as a result of renal cell carcinoma or adrenal cortical carcinoma, primary hyperaldosteronism is rarely associated with the latter."1.27Adrenal cortical carcinoma: an unusual cause of hyperaldosteronism. ( Telner, AH, 1983)
"Most diagnostic tests for primary aldosteronism use maneuvers to expand the extracellular fluid volume, thereby suppressing the renin-angiotensin system."1.27Single dose captopril as a diagnostic test for primary aldosteronism. ( Brown, RD; Carollo, ML; Hanson, CS; Kem, DC; Lyons, DF, 1983)
"A definite diagnosis of primary aldosteronism cannot be made during toxemia of pregnancy, and it is necessary to do serial determinations of plasma renin activity and plasma aldosterone concentration after delivery to confirm the diagnosis."1.27Elevation of plasma renin activity during pregnancy and rupture of a dissecting aortic aneurysm in a patient with primary aldosteronism. ( Akahoshi, M; Aoi, W; Doi, Y; Hashiba, K; Kuramochi, M; Shimizu, A; Suzuki, S; Utsunomiya, T, 1983)
"Her condition was diagnosed as primary aldosteronism without hypertension, which is very rare, based on an increased level of plasma aldosterone concentration, low plasma renin activity, and a typical finding of aldosterone-producing adenoma by adrenal scintigraphy."1.27A case of normotensive primary aldosteronism--comparison with 13 previously experienced cases with hypertension. ( Iimura, O; Kikuchi, K; Nakamura, Y; Nishimiya, T; Oimatsu, H; Ota, S; Shimamoto, K, 1984)
"Atenolol was orally given to 10 patients with essential hypertension once a day and changes in various parameters were observed through 24 hours."1.27Acute effect of atenolol on hemodynamic, plasma renin activity and plasma aldosterone concentration in the once daily oral administration. ( Arakawa, K; Sasaki, Y, 1984)
"Primary aldosteronism is a potentially curable cause of hypertension; it occurs in about 1% of hypertensive patients."1.27'Essential' hypertension with hypokalemia. Caused by aldosterone-secreting adrenal adenoma. ( Almog, C; Burke, M; Papo, J; Stavorovsky, M, 1984)
"Thirty-four patients with untreated Conn's syndrome were studied in a metabolic ward."1.27Relation of blood pressure with body and plasma electrolytes in Conn's syndrome. ( Beretta-Piccoli, C; Brown, JJ; Davies, DL; Ferriss, B; Fraser, R; Lasaridis, A; Lever, AF; Morton, JJ; Robertson, JI; Semple, PF, 1983)
"Arotinolol (S-596, ARL) is a beta-adrenoceptor blocking drug with weak alpha-adrenoceptor blocking activity, and may be classified into the fourth generation."1.27Chronic effects of arotinolol (S-596) in spontaneously hypertensive rats. ( Kawashima, K; Kishi, K; Saito, K; Sokabe, H, 1985)
"Ketanserin is a serotonin antagonist with high affinity for S2-serotonergic receptors, which mediate the vasoconstrictor effects of serotonin."1.27Ketanserin: a possible tool for studying the role of serotonin in hypertension. ( Boomsma, F; Man in't Veld, AJ; Schalekamp, MA; Wenting, GJ; Woittiez, AJ, 1985)
"25 mg and increasing dosage until blood pressure was adequately controlled."1.27Changes in the pathophysiologic profile of blood pressure determinants during short-term enalapril administration. ( Birkenhäger, WH; de Leeuw, PW, 1986)
"Systolic hypertension has emerged as another serious side effect in our experience."1.27Hypertension during extracorporeal membrane oxygenation: cause, effect, and management. ( Cullen, ML; Klein, MD; Lerner, GR; Sell, LL; Shanley, CJ; Whittlesey, GC, 1987)
" These results demonstrate that chronic administration of ANF not only reduces blood pressure and PRA in 2-K, 1-C hypertensive rats but also plasma and urinary aldosterone."1.27Effect of chronic infusion of atrial natriuretic factor on plasma and urinary aldosterone, plasma renin activity, blood pressure and sodium excretion in 2-K, 1-C hypertensive rats. ( Cantin, M; Garcia, R; Gutkowska, J; Thibault, G, 1986)
"Further volume expansion in liver cirrhosis by saline infusion led to the further increase in ANP (13."1.27Radioimmunoassay of atrial natriuretic peptide in human plasma: application to studies of volume and blood pressure homeostasis. ( Horký, K; Lachmanová, J; Srámková, J; Tesar, V; Widimský, J, 1988)
"Hyperaldosteronism was associated with the most pronounced deviations in the relationship between stimulants and aldosterone."1.27[Concentration of adrenocorticotrophic hormone and aldosterone secretion in essential hypertension and hyperaldosteronism]. ( Chikhladze, NM; Pershakova, LP; Shkhvatsabaia, IK; Uchitel', IA; Ustinova, SE, 1985)
"Enalapril (MK-421) was administered orally as a single dose of 2."1.27Effect of enalapril on renin, angiotensin converting enzyme activity, aldosterone and prostaglandins in patients with hypertension. ( Genest, J; Gutkowska, J; Hamet, P; Kuchel, O; Larochelle, P; Schiffrin, E, 1985)
"Mean captopril doses used were similar in both groups."1.27Effects of converting enzyme inhibition on blood pressure, plasma renin activity (PRA) and plasma aldosterone in hypertensive diabetics compared to patients with essential hypertension. ( Dineen, M; Kelleher, M; Sullivan, PA; Twomey, M, 1985)
"Cushing's syndrome is the consequence of a sustained overproduction of cortisol (hydrocortisone) by the adrenal cortex."1.27Diagnosis and pathophysiology of Cushing's syndrome. ( Gabrilove, JL; Krakoff, LR, 1986)
"Treatment with spironolactone alone for 2 months corrected hypertension, hypokalemic alkalosis, and all laboratory and radiologic evidence of rickets and hyperparathyroidism, resulting in acceleration of growth rate."1.27Spironolactone-reversible rickets associated with 11 beta-hydroxysteroid dehydrogenase deficiency syndrome. ( Arnhold, IJ; Batista, MC; Bloise, W; Kater, CE; Mendonça, BB; Nicolau, W; Rocha, A, 1986)
" In patients with severe renal failure, adjustment of the dose or the dosing frequency to the degree of renal failure is recommended to avoid administration of doses in excess of those required to achieve adequate inhibition of converting enzyme."1.27Lisinopril in hypertensive patients with and without renal failure. ( Boer, P; Geyskes, GG; van Schaik, BA, 1987)
" Enalapril in a dosage of 20 mg/day significantly and progressively lowered systolic and diastolic blood pressure at rest, with maximal decreases observed on the 120th day of the study period (P less than 0."1.27Effects of enalapril maleate on blood pressure, renin-angiotensin-aldosterone system, and peripheral sympathetic activity in essential hypertension. ( Carapelle, E; Carone, MB; Cerasola, G; Contorno, A; Cottone, S; D'Ignoto, G; Grasso, L, 1987)
" Although the group data support a reduction in peripheral sympathetic tone as associated with the decrease in BP for the thermal biofeedback condition, dose-response relations were not significant."1.27Biochemical changes associated with thermal biofeedback treatment of hypertension. ( Blanchard, EB; McCoy, GC; Morrison, S; Pallmeyer, TP; Pangburn, L; Siracusa, K; Wittrock, DA, 1988)
"Aldosterone excretion was in HL with EH substantially lower, and sodium excretion higher, than in a comparable group of lowland inhabitants."1.27Prevalence and clinical peculiarities of essential hypertension in a population living at high altitude. ( Dzhumagulova, AS; Meimanaliev, TS; Mirrakhimov, MM; Murataliev, TM; Rafibekova, ZhS; Shatemirova, KK, 1985)
"Aldosterone and dopamine were measured in the adrenal capsular portions (mostly zona glomerulosa) by radio-immunoassay and high-performance liquid chromatography, respectively."1.27Dopamine and aldosterone in adrenal glomerulosa cells in spontaneously hypertensive rats. ( Atarashi, K; Hayakawa, H; Hirata, Y; Matsuoka, H; Sugimoto, T; Takagi, M, 1988)
"Aldosterone was lower (p less than 0."1.27Sodium sensitivity in human subjects. Hemodynamic and hormonal correlates. ( Ratts, TE; Sullivan, JM, 1988)
"Aldosterone only was elevated in 3 cases, while PRA was elevated in 2."1.27The pattern of plasma renin activity and aldosterone system in patients with sustained hydronephrosis. ( Ezzat, M, 1987)
" In vitro dose-response curves to NE and TNS were not significantly different."1.27Effect of high calcium intake on pressor responsivity in hypertensive rats. ( Berger, M; Brickman, AS; Eggena, P; Golub, M; Lee, DB; Nyby, M; Stern, N; Tuck, ML, 1987)
"Hyperaldosteronism in the patients with renal-parenchymatous and essential arterial hypertension was regarded as secondary in a stable and malignant course of arterial hypertension."1.27[Radioimmunologic determination of aldosterone and renin in the blood in the diagnosis of different forms of arterial hypertension]. ( Khalmuratova, RA; Khamidov, RI; Sattarova, FK, 1987)
"The treatment with nifedipine induced a significant reduction in both systolic and diastolic blood pressures; the infusions of angiotensin II (0."1.27Calcium antagonists and responsiveness of the adrenal glands to aldosterone-releasing stimuli in hypertensive patients. ( Leonetti, G; Terzoli, L; Zanchetti, A, 1987)
" Dose-response studies on the icvt infusion of ALD were carried out in sensitized and non-sensitized (intact, with tap water to drink) male Sprague-Dawley rats (SDR)."1.27Dose-response studies of intracerebroventricular infusion of aldosterone in sensitized and non-sensitized rats. ( Gomez Sanchez, EP, 1988)
"Essential hypertension is thought to produce a uniform exaggerated natriuresis and diuresis."1.27Spectrum of deranged sodium homeostasis in essential hypertension. ( Epstein, M; Levinson, R; Loutzenhiser, R, 1986)
") alone or in combination with furosemide (1 mg/kg, i."1.27The effects of acebutolol alone and in combination with furosemide or hydralazine in experimentally induced hypertensive G-minipigs. ( Hidaka, H; Sawada, S; Tanioka, Y; Yasuda, Y, 1986)
"Hypertension is a common finding in patients with Cushing's syndrome (CS), but the cause is unknown."1.27Elevated urinary 19-Nor-deoxycorticosterone glucuronide in Cushing's syndrome. ( Ehlers, ME; Griffing, GT; Melby, JC; Wilson, TE, 1987)
"Minoxidil treatment lowered blood pressure from 178/112 +/- 8/5 mm Hg (means +/- SEM) to 14/95 +/- 6/3 mm Hg."1.26Treatment of drug-resistant hypertension with minoxidil or angiotensin-converting enzyme inhibitor: blood pressure, renin, aldosterone, and electrolyte responses. ( Baer, L; Radichevich, I; Williams, GS, 1980)
"Captopril was given in biweekly, doubling doses starting with 25 mg 3 times a day until control of blood pressure was achieved or a total daily dosage of 600 mg was reached."1.26Dose response in captopril therapy of hypertension. ( Amery, A; Fagard, R; Lijnen, P; Staessen, J; Verschueren, LJ, 1980)
"Aldosterone secretion was temporarily suppressed after dexamethasone administration and was stimulated by exogenous ACTH."1.26Primary aldosteronism due to unilateral adrenal hyperplasia. ( Ganguly, A; Luetscher, JA; Zager, PG, 1980)
"Captopril was given to pregnant and nonpregnant animals during the developmental phase of hypertension and to nonpregnant animals with established (4 weeks of treatment) hypertension."1.26Aldosterone-induced hypertension: effects of a kininase inhibitor. ( Douglas, BH; Evans, TA; Lundy, JH; Parks, BR, 1980)
"Aldosterone levels were unresponsive to variations in dietary salt intake and plasma renin activity was suppressed."1.26Dexamethasone suppressible hyperaldosteronism in a child with nephrosclerosis. ( Lee, SM; Levine, L; Lightner, E; New, MI; Oberfield, S; Witte, M, 1982)
"Enalapril was well tolerated."1.26Effects of enalapril, a new converting enzyme inhibitor, in hypertension. ( Ferguson, RK; Hichens, M; Huber, PB; Irvin, JD; Mojaverian, P; Swanson, BN; Vlasses, PH, 1982)
"PGF2 alpha was the same in preeclampsia and normotensive pregnancy but higher than in the non-pregnant group."1.26Prostaglandins, catecholamines, renin and aldosterone during hypertensive and normotensive pregnancy. ( Christensen, NJ; Christensen, P; Johannesen, P; Kornerup, HJ; Kristensen, S; Lauritsen, JG; Leyssac, PP; Pedersen, EB; Rasmussen, AB; Wohlert, M, 1982)
"Screening tests for primary aldosteronism were compared in 22 patients with this disorder and 140 hypertensive controls."1.26Simplified screening procedures for primary aldosteronism. Studies on the mechanism of the hyper-responsiveness to furosemide and standing. ( Anderson, GH; Streeten, DH, 1982)
"Aldosterone excretion was established to be normal in 55."1.26[Urinary excretion of aldosterone in patients with hypertension]. ( Elenkova, A; Grigorova, R, 1982)
"Captopril was used in primary and long-term treatment of 40 treatment-resistant hypertensive patients."1.26Long-term efficacy of captopril in renovascular and essential hypertension. ( Atlas, SA; Case, DB; Laragh, JH; Marion, RM, 1982)
"We report a case of primary hyperaldosteronism in a 37-year-old woman presenting early in pregnancy with hypertension and hypokalaemia."1.26Primary hyperaldosteronism in pregnancy. ( Buchanan, JD; Hammond, TG; Scoggins, BA; Thatcher, R; Whitworth, JA, 1982)
"Twenty-four patients with primary aldosteronism were studied."1.26Fludrocortisone suppression test in normal subjects, in patients with essential hypertension and in patients with various forms of aldosteronism. ( Lund, JO; Nielsen, MD, 1980)
"In primary aldosteronism, high UA and PAC together with suppressed PRA represent an important diagnostic guideline for differentiation from other types of low-renin hypertensions."1.26Renin-angiotensin-aldosterone system in arterial hypertension. ( Gregorová, I; Horký, K, 1980)
" Both systolic and diastolic blood pressures (BP) decreased significantly during the lower dosage (p < 0."1.26The renin-aldosterone system in low-dose chlorothiazide treatment of hypertensive subjects. ( Lammintausta, K; Lammintausta, R, 1980)
"Essential hypertension is not a disease entity, so therefore it is understood that there are several causes of its development."1.26Different patterns in essential hypertension and possible choice of antihypertensive drugs. ( Koster, M, 1980)
" With the long-term use of diuretics and various kinds of antihypertensive drugs in the treatment of high blood pressure in patients with PA, normal basal level and responsiveness of PRA were observed."1.26[Clinical observation of 12 cases of primary aldosteronism, special reference to the diagnostic problem (author's transl)]. ( Hata, S; Ito, Y; Kadena, N; Kunita, H; Nakagawa, K; Nakagawa, S; Obara, T; Okamoto, M; Suzuki, H, 1980)
"Captopril (SQ 14."1.26Captopril in primary hypertension. Effects related to the renin-angiotensin-aldosterone and kallikrein-kinin systems. ( Karlberg, BE; Nilsson, OR; Ohman, KP; Wettre, S, 1981)
"Hypertension was uncommon when bilateral nephrectomy had been performed."1.26Hypertension following renal transplantation: the role of the host's kidney. ( Liano, F; Marcen, R; McHugh, MI; Robson, V; Tanboga, H; Wilkinson, R, 1980)
"Spironolactone was indicated preoperatively for all surgical candidates, for non-operated APA patients, and for all IHA patients."1.26Primary aldosteronism -- screening, diagnosis and therapy. ( Gregorová, I; Horký, K; Hradec, E; Silinková-Málková, E; Vancura, J, 1981)
"1."1.26Effect of angiotensin II and converting enzyme inhibitor (captopril) on blood pressure, plasma renin activity and aldosterone in primary aldosteronism. ( Armanini, D; Boscaro, M; Fallo, F; Mantero, F; Opocher, G; Scaroni, C, 1981)
"Thus screening for primary aldosteronism can be restricted to hypokalaemic patients."1.26Simple screening procedure for the diagnosis of primary aldosteronism. ( Giese, J; Lund, JO; Nielsen, MD, 1981)
"1 Labetalol was administered to 18 hypertensive patients for an average duration of 2."1.26Response of the systemic pulmonary circulation to labetalol at rest and during exercise. ( Amery, A; Fagard, R; Lijnen, P, 1982)
"Low-renin hypertension was diagnosed by the presence of hypertension, hypokalaemic alkalosis, suppressed plasma renin activity and low plasma aldosterone."1.26Low-renin, low-aldosterone hypertension and abnormal cortisol metabolism in a 19-month-old child. ( Fiselier, TJ; Honour, JW; Monnens, LA; Otten, BJ; van Munster, PJ, 1982)
"Deoxycorticosterone (DOC) levels were significantly lower at 8 weeks and 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) were lower at 16 weeks of age."1.26Role of adrenal steroidogenesis in etiology of hypertension in the spontaneously hypertensive rat. ( Dale, SL; Komanicky, P; Melby, JC; Reiss, DL, 1982)
" The syndrome was iatrogenic in two cases depending on the licorice eating and the combined use of diuretics and a 9-alpha-fluoroprednisolone-containing nasal spray in one patient, and on a long-term use of the same nasal decongestant in the other."1.26[Hypokalemic myopathy in arterial hypertension]. ( Angeletti, G; Filipponi, P; Natali, P; Nicoletti, I; Nunzi, E; Rambotti, P; Santeusanio, F, 1982)
"In most of the patients examined hyperaldosteronism was found, which was attended by an increased percentage of 14C-aldosterone binding with aldosterone binding globulin (ABG) and particularly with glucocorticoid binding globulin (GBG)."1.26[14C-aldosterone binding by plasma proteins in adolescents with primary arterial hypertension]. ( Bakova, VV; Golov, AG; Kucherenko, AG; Markov, KhM, 1981)
"Amiloride was disproportionately potent in lowering serum bicarbonate, and the data do not suggest that these drugs elevate plasma potassium simply by correcting metabolic alkalosis."1.26Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients. ( Fraser, R; Hettiarachchi, J; Morton, JJ; Ramsay, LE, 1980)
"Propranolol therapy was associated with a 25% decrease in PRA (p less than 0."1.26Effects of propranolol on aldosterone plasma concentration and aldosterone metabolic clearance in hypertensive patients. ( Grim, CE; Parkinson, CA; Pratt, JH, 1980)
"Hyperparathyroidism and hyperaldosteronism coexisted in association with medullary sponge kidneys in a 27-year-old woman with severe hypertension."1.26Hyperaldosteronism, hyperparathyroidism, medullary sponge kidneys, and hypertension. ( Hellman, DE; Kartchner, M; Komar, N; Mayes, D; Pitt, M, 1980)
"Aldosterone-oxime was labelled with 125I by using the chloramine T method described by Hunter and Greenwood."1.26[A simple method for measuring aldosterone secretion rate using 125I-aldosterone (authors' transl)]. ( Fukuchi, S; Haruyama, K; Toki, T; Yamazaki, M, 1980)
"Two of nine patients with primary aldosteronism had normal Also-18-G excretion but elevated TH-Aldo excretion."1.26Urinary tetrahydroaldosterone and aldosterone-18-glucuronide excretion in white and black normal subjects and hypertensive patients. ( Gomez-Sanchez, CE; Holland, OB, 1981)
"Four patients with hyperaldosteronism due to adrenal adenomas served as controls."1.26The role of ACTH in the episodic release of aldosterone in patients with idiopathic adrenal hyperplasia, hypertension, and hyperaldosteronism. ( Gomez-Sanchez, C; Higgins, JR; Kem, DC; Kramer, NJ; Weinberger, MH, 1976)
"High aldosterone was more often in patients with high renin, and low levels of aldosterone were usual in those with low and normal renin."1.26The mechanism of low-renin hypertension: aldosterone response to sodium restriction and upright posture, angiotensin II, ACTH and potassium in patients with hypertension. ( Kondo, K; Matsuki, S; Misumi, J; Nakamura, R; Saito, I; Saruta, T, 1976)
"The hypothesis that hyperaldosteronism is not the sole cause of hypertension in dexamethasone-suppressible hyperaldosteronsim was tested in an 18-year-old male."1.26Evidence for an unidentified ACTH-induced steroid hormone causing hypertension. ( Levine, LS; New, MI; Peterson, RE; Saenger, P, 1976)
"Primary hyperaldosteronism usually causes moderate hypertension."1.26[Primary hyperaldosteronism with paroxysmal arterial hypertension. Apropos of 2 operated cases]. ( Griffe, J; Morin, PP; Tatibouet, L, 1978)
"These data show that patients with hyperaldosteronism from an adrenal adenoma or hyperplasia have a consistent and exaggerated response to ACTH."1.26Plasma aldosterone response to ACTH in primary aldosteronism and in patients with low renin hypertension. ( Gomez-Sanchez, C; Higgins, JR; Holland, OB; Kem, DC; Kramer, NJ; Weinberger, MH, 1978)
"Aldosterone levels were subnormal but as yet there has been no evidence of overproduction of other mineralocorticoids by chemical analysis or by bioassay of plasma and urinary extracts."1.26A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol. ( Bradlow, HL; Gunczler, P; Levine, LS; New, MI; Ramirez, LC; Rauh, W; Rösler, A; Ulick, S; Zanconato, G, 1979)
"The effects of hydralazine (3 mg/kg) and the angiotensin I-converting enzyme (ACE) inhibitor captopril (SQ 14,225) (100 mg/kg) on mean arterial blood pressure, plasma renin activity, urinary volume and urinary Na+,K+, and aldosterone concentrations were examined in spontaneously hypertensive rats of the Okamoto and Aoki strain (SHR) after oral daily dosing for 2 weeks, 3 or 6 months."1.26Effects of chronic treatment with captopril (SQ 14,225), an orally active inhibitor of angiotensin I-converting enzyme, in spontaneously hypertensive rats. ( Antonaccio, MJ; Goldberg, ME; Harris, DN; High, JP; Horovitz, ZP; Laffan, RJ; Rubin, B; Zaidi, I, 1979)
"2."1.26The natural history of hypertension in turkeys. ( Dal Palù, C; Pagnan, A; Pessina, AC; Thiene, G, 1978)
"1."1.26Effects of labetalol on systemic and pulmonary haemodynamics at rest and during exercise in hypertensive patients. ( Amery, A; Billiet, L; Fagard, R; Lijnen, P; Reybrouck, T, 1978)
""Outpatient hyperkalemia" is a new clinical syndrome in which high serum potassium levels (SK) are found in the outpatient condition returning toward normal without any specific treatment after admission to the hospital."1.26"Outpatient hyperkalemia" syndrome in renal and hypertensive patients with suppressed aldosterone production. ( Boer, P; Dorhout Mees, EJ; Rado, JP; Simatupang, T, 1979)
"Post-transplant hypertension has been observed in 98 renal allograft recipients who had good renal function and whose follow-up was more than 15 months."1.26Late hypertension following renal allotransplantation. ( Beaudoin, JG; Guttmann, RD; Klassen, J; Knaack, J; Morehouse, DD; Pollini, J, 1979)
"Patients with proved aldosteronism are outside the normal ranges of plasma renin activity."1.26Evaluation of patients for secondary hypertension. ( Donohue, JP; Grim, CE; Weinberger, MH, 1979)
"Experimental toxemia of pregnancy was induced in 8 pregnant monkeys (Macacamulatta) by reducing the abdomiinal aorta to one-third of its original diameter during the last month of gestation."1.26Experimental toxemia of pregnancy in the monkey, with a preliminary report on renin and aldosterone. ( Abitbol, MM; Driscoll, SG; Gallo, GR; Ober, MB; Pirani, CL, 1977)
" The findings indicate that different regulatory mechanisms are activated during acute and chronic administration of nifedipine."1.26Effect of nifedipine on plasma renin, aldosterone and catecholamines in arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Mikkelsen, E; Pedersen, EB; Pedersen, OL, 1979)
"1."1.26Blood pressure reduction by incremental infusion of labetalol in patients with severe hypertension. ( Brown, JJ; Cummings, AM; Fraser, R; Lever, AF; Morton, JJ; Richards, DA; Robertson, JI, 1979)
" The data shows that this dosage of spironolactone gave minor adjustments of the systemic and renal circulation in spite of the consistent changes in BW, PV, PRA and PA."1.26Haemodynamic effects of treatment and withdrawal of spironolactone in essential hypertension. ( Falch, DK; Johansson, R; Norman, N; Odegaard, AE, 1979)
"Triamterene was administered in a dose of 100 mg/day for 8 days to 7 patients with essential hypertension."1.26Effect of triamterene on urinary excretion of immunoreactive prostaglandin E in essential hypertension. ( Abe, K; Chiba, S; Irokawa, N; Ito, T; Otsuka, Y; Saito, K; Sakurai, Y; Sato, M; Yasujima, M; Yoshinaga, K, 1979)
"Treatment with spironolactone did not significantly alter the natriuretic response of the spontaneously hypertensive rats (43 +/- 8 mueq/h) to another salt load, but increased the natriuretic response of the normotensive rats (55 +/- 7 mueq/h) to that of the hypertensive rats."1.26Aldosterone in the exaggerated natriuresis of spontaneously hypertensive rats. ( Bauer, JH; Willis, LR, 1978)
"Of these, 13 had primary aldosteronism (ALDO), 19 high renin (HRH), 30 low renin (LRH), and 57 normal renin (NRH) essential hypertension."1.26Natriuretic response to saline infusion in normotensive and hypertensive man. The role of renin suppression in exaggerated natriuresis. ( Grim, CE; Higgins, JT; Luft, FC; Weinberger, MH; Willis, LR, 1977)
"The hypertension was accompanied by expansion of plasma volume, retention of sodium, and alteration in urinary Na/K ratio."1.26Isolation of a hypertension-producing compound from normal human urine. ( Bravo, EL; Bumpus, FM; Sen, S, 1977)
"Aldosterone excretion was low."1.26Steroid profile in a case of adrenal carcinoma with severe hypertension. ( Forman, BH; Genel, M; Mulrow, PJ; Tan, SY, 1977)
"Twenty patients suffering from primary hyperaldosteronism were studied."1.26[The renin-angiotensin-aldosterone system in hypertensive patients. II. Diagnosis of primary hyperaldosteronism]. ( Benguigui, L; Corvol, P; Houde, M; Menard, J; Milliez, P; Tonnelier, M, 1977)
"We examined the acute and chronic dose-response relationships between intravenously infused angiotensin II (A II) and the resulting changes in arterial pressure and plasma aldosterone concentration at varying levels of sodium intake."1.26Acute and chronic dose-response relationships for angiotensin, aldosterone, and arterial pressure at varying levels of sodium intake. ( Cowley, AW; McCaa, RE, 1976)
" In normal subjects, Sar1-Ile-AII showed pressor (agonistic) activity, which was related to both dosage and sodium intake."1.26Changes of blood pressure, plasma renin activity and plasma aldosterone concentration following the infusion of Sar1-Ile8-angiotensin II in hypertensive, fluid and electrolyte disorders. ( Doi, K; Hata, T; Ichihara, K; Kumahara, Y; Ogihara, T; Yamamoto, T, 1976)
"In spironolactone-treated rats blood pressure and total aortic renin concentrations were comparable with those in the control rats."1.26Effects of aldosterone and spironolactone on arterial renin in rats. ( Rosenthal, J, 1976)
"In two patients with primary hyperaldosteronism, the aldosterone excretion during the night was relatively more elevated than in the day."1.26[Diurnal variation in the urinary excretion of vanilmandelic acid and aldosterone in normal and hypertensive persons (author's transl)]. ( Deck, KA; Eberlein, L; Luedtke, A, 1976)
"Hypertension was produced in 25 rabbits by constricting the right renal artery and leaving the opposite kidney intact (two-kidney hypertension)."1.26Renin-angiotensin-aldosterone system in experimental renal hypertension in the rabbit. ( Davis, JO; Lohmeier, TE, 1976)
"Hypokalemic hypertension is the leading symptome of the disease."1.26[Primary aldosteronism]. ( Beckerhoff, R; Braun, KP; Furrer, J; Nussberger, J; Pouliadis, G; Siegenthaler, W; Sobbe, A; Vetter, H; Vetter, W; Witassek, F, 1976)
"Low-renin hypertension was not characterized by increased exchangeable sodium, but exchaneable postassium was significantly lower than in patients with normal plasma-renin."1.25Is low-renin hypertension a stage in the development of essential hypertension or a diagnostic entity? ( Beevers, DG; Brown, JJ; Davies, DL; Lever, AF; Padfield, PL; Robertson, JI; Schalekamp, MA; Tree, M, 1975)
"Aldosterone secretion was elevated markedly in dexamethasone-morphine-treated spontaneously hypertensive rats at both 7-8 and 11-13 weeks of age but was not significantly different from control in 22-25-week-old spontaneously hypertensive rats."1.25Control of aldosterone secretion in the spontaneously hypertensive rat. ( Aharon, NV; Davis, JO; Freeman, RH; Ulick, S; Weinberger, MH, 1975)
"Propranolol was given to 10 hypertensive patients with CGN and hypotensive effect on renal function was observed."1.25Therapy and prognosis of hypertension in chronic nephritis. ( Kajiwara, N, 1975)
"Five obvious cases of hyperaldosteronism were found among the 16 low-renin patients."1.25Abnormally sustained aldosterone secretion during salt loading in patients with various forms of benign hypertension; relation to plasma renin activity. ( Collins, RD; Dowdy, AJ; Gonzales, CM; Luetscher, JA; Nokes, GW; Weinberger, MH, 1970)
"Hypertension was initially ameliorated but was not cured."1.25Periodic hypokalaemic paralysis, adrenal adenoma, and normal colonic transport of sodium and potassium. ( Jones, MB; Peart, WS; Richards, P, 1973)

Research

Studies (5,104)

TimeframeStudies, this research(%)All Research%
pre-19902321 (45.47)18.7374
1990's690 (13.52)18.2507
2000's802 (15.71)29.6817
2010's852 (16.69)24.3611
2020's439 (8.60)2.80

Authors

AuthorsStudies
Liu, X5
Jin, L1
Zhang, H6
Ma, W1
Song, L3
Zhou, X4
Cai, J2
Perrin, EC1
South, AM2
Carides, MD1
Sishuba, NT1
Bombil, I1
Christofides, C1
Veldhuizen, GP6
Alnazer, RM6
de Leeuw, PW23
Kroon, AA9
Memon, SS1
Lila, A1
Barnabas, R1
Goroshi, M1
Sarathi, V1
Shivane, V1
Patil, V1
Shah, N1
Bandgar, T1
Betz, MJ1
Zech, CJ1
Tang, WW1
Ma, WX1
Sun, SY1
Ran, XW1
Hu, Z1
Chen, X5
Shao, Y1
Luo, FX1
Chu, SL3
Wang, JG6
Hundemer, GL9
Imsirovic, H2
Vaidya, A19
Yozamp, N3
Goupil, R2
Madore, F2
Agharazii, M2
Knoll, G2
Sood, MM2
Chen, HH4
Wan, SH1
Iyer, SR2
Cannone, V3
Sangaralingham, SJ5
Nuetel, J1
Burnett, JC10
Gromotowicz-Poplawska, A2
Flaumenhaft, R1
Gholami, SK3
Merrill-Skoloff, G1
Chabielska, E2
Williams, GH73
Romero, JR3
Ishihara, Y3
Umakoshi, H9
Kaneko, H4
Nanba, K5
Tsuiki, M15
Kusakabe, T2
Satoh-Asahara, N3
Yasoda, A5
Tagami, T3
Petramala, L6
Concistrè, A4
Circosta, F1
Gigante, A1
Sarlo, F1
Schina, M1
Soldini, M1
Iannucci, G3
Cianci, R2
Letizia, C22
Haas, AV3
En Yee, L1
Yuan, YE2
Wong, YH1
Hopkins, PN14
Jeunemaitre, X24
Lasky-Su, J3
Williams, JS12
Adler, GK14
Warchoł-Celińska, E1
Prejbisz, A6
Dobrowolski, P2
Wypasek, E1
Kądziela, J1
Kołodziejczyk-Kruk, S2
Kabat, M2
Undas, A1
Januszewicz, A7
Yuan, Y2
Li, N10
Liu, Y15
Wang, M6
Heizhati, M8
Zhu, Q4
Yao, X7
Luo, Q8
Lin, M6
Gan, L6
Zhang, D6
Abulikemu, S1
Wang, G3
Jiang, W2
Hu, J9
Maimaiti, N2
Wang, L4
Wu, T3
Sun, L1
Yue, N2
Ren, Y7
Reincke, M33
Bancos, I5
Mulatero, P34
Scholl, UI6
Stowasser, M41
Williams, TA10
McNally, RJ3
Farukh, B3
Chowienczyk, PJ4
Faconti, L3
Pastén, V1
Tapia-Castillo, A6
Fardella, CE23
Leiva, A1
Carvajal, CA16
Zekarias, K1
Tessier, KM1
Fuss, CT3
Hahner, S3
Heinrich, DA6
Adolf, C8
Sen, R1
Sengupta, D1
Mukherjee, A1
Evans, J1
Ward, J1
Domenig, O2
Mochel, JP2
Creevy, K1
Zhang, W3
Chang, G2
Cao, M1
Zhou, K3
Markou, A13
Kaltsas, GA1
Papanastasiou, L8
Gravvanis, C2
Voulgaris, N3
Kanti, G1
Zografos, GN1
Chrousos, GP8
Piaditis, G7
Imiela, AM1
Mikołajczyk, TP1
Siedliński, M1
Konior-Rozlachowska, A1
Wróbel, A1
Biernat-Kałuża, E1
Januszewicz, M1
Guzik, B1
Guzik, TJ1
Terock, J1
Hannemann, A4
Klinger-König, J1
Janowitz, D1
Grabe, HJ1
Murck, H2
Pérez, JA2
Araujo-Castro, M2
Parra-Ramírez, P1
Vanderriele, PE1
Wang, Q2
Mérillat, AM1
Ino, F1
Aeschlimann, G1
Ehret, X1
Ancin Del Olmo, D1
Ponce de León, V1
Winter, DV1
Odermatt, A3
Hummler, E4
Verouti, SN1
Schiavone, D5
Iacobone, M3
Rossi, GP49
Tan, SJ1
Libianto, R9
Yang, J21
Wong, J1
Hong, J3
Parksook, WW2
Heydarpour, M2
Luther, JM4
Pojoga, LH7
Gulhan, B1
Ünsal, Y1
Baltu, D1
Çelik Ertaş, NB1
Özdemir, G1
Utine, E1
Ozcan, HN1
Duzova, A1
Gönç, N1
Dzhoyashvili, NA1
Yan, Y2
Sun, HW1
Qi, Y1
Funder, JW36
Carey, RM10
Wang, Y6
Li, CX1
Lin, YN1
Zhang, LY1
Li, SQ1
Zhang, L5
Yan, YR1
Lu, FY1
Li, QY1
Asbach, E3
Lewandowski, KC2
Tadros-Zins, M2
Horzelski, W2
Grzesiak, M1
Lewinski, A2
Rizzolo, K1
Beck, NM1
Ambruso, SL1
Wannachalee, T3
Lieberman, L1
Turcu, AF11
Kametas, NA1
Nzelu, D1
Nicolaides, KH1
Chauhan, K1
Schachna, E1
Ryan, J1
Hutton, H1
Fuller, PJ16
Wilson, S1
Kerr, PG1
Arnold, N1
Hermanns, IM1
Schulz, A1
Hahad, O1
Schmitt, VH1
Panova-Noeva, M1
Prochaska, JH1
Binder, H1
Pfeiffer, N1
Beutel, M1
Lackner, KJ1
Münzel, T1
Wild, PS1
Russell, GM1
Gwini, SM6
Nuttall, P1
Shen, J5
Young, MJ11
Stanley, JC1
Ward, JL1
Guillot, E1
Ware, WA1
Yuan, L1
Hengel, FE1
Benitah, JP1
Wenzel, UO1
Choy, KW7
Simpson, I1
Xu, W3
Yang, YM1
Zhu, J3
Wu, S1
Wang, J10
Shao, XH1
Lattanzio, MR1
Weir, MR6
Ogata, M4
Wada, N18
Ichijo, T12
Sakamoto, S1
Watanabe, T6
Iwahashi, N2
Fukumoto, T3
Terada, E1
Katsuhara, S1
Yokomoto-Umakoshi, M3
Matsuda, Y9
Sakamoto, R8
Ogawa, Y12
Chen, YJ1
Peng, KY4
Chueh, JS4
Liao, HW2
Hsieh, TY1
Wu, VC28
Wang, SM9
Mermejo, LM1
Elias, PCL1
Molina, CAF1
Tucci, S1
Muglia, VF1
Elias, J1
Antonini, SR1
de Castro, M1
Moreira, AC1
Morselli, F1
Naruse, M22
Katabami, T14
Shibata, H15
Sone, M12
Takahashi, K9
Tanabe, A14
Izawa, S6
Otsuki, M5
Omura, M5
Oki, Y1
Kurihara, I15
Kobayashi, H13
Satoh, F7
Takeda, Y36
Tanaka, T5
Tamura, K12
Hashimoto, S8
Hasegawa, T3
Yoshimoto, T12
Yoneda, T24
Yamamoto, K11
Rakugi, H5
Saiki, A2
Ohno, Y2
Haze, T4
Mogi, M2
Asla, Q1
Sardà, H1
Lerma, E1
Hanzu, FA1
Rodrigo, MT1
Urgell, E1
Pérez, JI1
Webb, SM1
Aulinas, A1
Russell, G3
Li, Q8
Leenaerts, M1
Weber, T1
Amar, J5
de Backer, T3
Burkard, T1
van der Giet, M2
Gosse, P6
Kahan, T3
Mancia, G1
Mayer, CC1
Muiesan, ML9
Stergiou, GS1
Tsioufis, K1
Vaisse, B4
Kreutz, R1
Liu, Z5
Deng, X2
Luo, L1
Li, S4
Li, M4
Deng, Q1
Zhong, W1
Oh, AR1
Park, J1
Lee, JH4
Min, JJ1
Gook, J1
Jang, JN1
Lee, SH1
Kim, K1
Ahn, J1
Liang, J1
Dong, H3
Wang, H7
Yi, Z1
Jiang, G1
Inagaki, T1
Gomez-Sanchez, CE26
Dong, J1
Ueda, H2
Nguyen, V1
Tu, TM1
Mamauag, MJB1
Lai, J1
Saffari, SE1
Aw, TC1
Ong, L1
Foo, RSY1
Chai, SC1
Fones, S1
Zhang, M2
Puar, TH2
Xiamili, Z2
Tong, L2
Lin, Y2
Bioletto, F2
Bollati, M2
Lopez, C3
Arata, S2
Procopio, M2
Ponzetto, F2
Ghigo, E5
Maccario, M13
Parasiliti-Caprino, M6
Mahanaimy, M1
Finkel, U1
Barda, N1
Rottman, E1
Balicer, R1
Berliner Senderey, A1
Feldman, B1
Chang, CM1
Chan, CK2
Lin, YF1
Chang, JG1
Wu, MS2
Chang, WC1
Ariens, J1
Horvath, AR1
Loader, J1
Taylor, FC1
Lampa, E1
Sundström, J3
Zhu, Y4
Wang, Z8
Liu, C2
Liu, S4
Li, X4
Chen, R1
Zhan, Y1
Wang, S2
Zeng, X1
Yoon, M1
Hong, N1
Ha, J2
Lee, CJ2
Ku, CR1
Rhee, Y1
Park, S4
Sanga, V1
Rossitto, G8
Seccia, TM20
Nainani, AK1
Peters, S1
Tsampasian, V1
Corballis, N1
Vassiliou, VS1
Yang, Y5
Wu, C2
Qu, D1
Xu, X3
Chen, L1
Sun, Q1
Zhao, X2
Carasel, A1
Calissendorff, J2
Avander, K1
Shabo, I1
Volpe, C3
Falhammar, H1
Nomura, M4
Itoh, H16
Oki, K8
Yamada, T8
Inagaki, N9
Yabe, D1
Takahashi, Y3
Suzuki, T13
Ueda, T3
Tsurutani, Y1
Osada, J1
Inoue, K2
Hoshino, Y1
Ono, M2
Nakai, K1
Saito, J3
Yumoto, K1
Nishikawa, T11
Santana, LS1
Guimaraes, AG1
Almeida, MQ4
Berzuini, C1
Bernardinelli, L1
Pitsava, G1
Faucz, FR1
Stratakis, CA4
Hannah-Shmouni, F2
Nhan, W1
Grigoryan, S1
Urban, C1
Liu, H5
Holevinski, L1
Zhao, L3
Matsumoto, T4
Doi, S2
Nakashima, A4
Ike, T1
Sasaki, K1
Masaki, T6
Spyroglou, A2
Handgriff, L3
Müller, L1
Schwarzlmüller, P1
Remde, H1
Hirsch, A1
O'Toole, SM1
Thuzar, M2
Deflorenne, E1
Amar, L11
Vrckovnik, R1
Kocjan, T3
Zhang, CD1
Li, D1
Singh, S2
Murakami, M8
Quinkler, M9
Drake, WM3
Fassnacht, M2
Beuschlein, F16
Koo, P1
Muntner, P1
Hall, ME4
Gjelsvik, A1
McCool, FD1
Eaton, CB1
Cheng, JY1
Wong, FC1
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Cheng, TH1
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Chan, AS1
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Ho, CS1
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Kater, CE5
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Maciel, AAW3
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Fagundes, GFC3
Petenuci, J3
Vilela, LAP3
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Goldbaum, TS3
Zerbini, MCN3
Ledesma, FL3
Tanno, FY3
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Cavalcante, ACBS3
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Pilan, B3
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Bortolotto, LA4
Latronico, AC3
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van der Linden, EL3
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Van Haelst, AJ1
Benraad, HB1
Kojima, M1
Tano, T1
Kajihara, N1
Yano, T1
Idemura, R1
Odagiri, E1
Kosman, ME1
Concolino, G1
Urbani, S1
Krauss, XH1
Schalekamp, MP1
Cruz, IA1
Dillard, MG1
Hosten, AO1
Denton, D1
Jones, J1
Douglas, JG1
Hatake, S1
Stoker, LM1
Dargie, HJ1
Kennedy, AC1
Ward, DM1
King, PC1
Bondarenko, BB2
Berndt, A1
Müller, B1
Bel, A1
Rousset, H1
Fournier, G1
Salomon, MI1
Tchertkoff, V1
Kert, MJ1
Tarr, LW1
Franklin, S1
Gold, E1
Okun, R1
Nakache, JP2
Salmon, D2
Kazandjian, M2
Baulon, A2
Lagrue, G2
Just, HJ1
Burden, RP1
Booth, LJ1
Mancheno-Rico, E1
Seth, KK1
Dawson, K1
Bookstein, JJ1
Rosset, G1
Dart, RA1
Tremann, JA1
Gibbons, RP1
Correa, RJ1
Dürr, F2
Euchenhofer, M2
Würz, H2
Streicher, E2
Howes, EL1
Noakes, CA1
Jones, MB1
Okong'o, O1
Manasseh, PK1
Fleischer, N1
de Lange, WE1
Weeke, A1
Artz, W1
Jansen, W1
Doorenbos, H1
Miyazaki, G1
Sasano, N1
Kelch, RP1
Connors, MH1
Kaplan, SL1
Grumbach, MM1
Vaisrub, S1
Guest, S1
Shtel'makh, NI1
Kamyshan, NA1
Ashcheulova, IK1
Gavrik, TI1
Hitzenberger, G1
Kovacs, K2
Horvath, E1
Piyasena, RD1
Ekins, RP1
Feldman, D1
Vaccaro, E1
Solitro, A1
McCaa, CS1
Miyahara, M1
Kukuiri, T1
Sai, Z3
Weil, MH1
Shubin, H1
Toussaint, C1
Naets, JP1
Corvilain, J1
Lambert, PP1
Seaman, MP1
Koshikawa, S1
Shiigai, T1
Ideura, T1
Kategawa, H1
Nielsen, I2
Moller, I1
Păun, R1
Ionescu-Tîrgovişte, C1
Mićić, R1
Lebedev, VP1
Vodolazhskaia-Levina, EE1
Chemidze, NP1
Khovanskaia, MP1
Kalashnikova, OA1
Aitchison, J1
Johns, VJ1
Bhatia, S1
Koppes, G1
Luton, JP1
Laudat, P1
Lemmer, M1
Nowaczynski, WJ1
Ferencíková, J1
Baláz, V1
Marek, J2
Slabý, A1
Wisenbaugh, PE1
Hull, C1
Freedman, RJ1
Matthews, DN1
Hadady, M1
James, IM1
Imada, A1
Hammann, K1
Fischer, N1
Castleman, B1
Scully, RE1
McNeely, BU1
Amsterdam, EA2
Dobrzinsky, SJ2
Finnerty, FA1
Cashion, WR1
Nugent, CA2
Mulrow, RJ1
Morrow, LB1
Shutkin, PM1
Marieb, N1
Yorifuji, S1
Kahn, PC2
Kelleher, MD1
Egdahl, BH1
Eversman, JJ1
Humphrey, DC1
Peters, TJ1
Maher, JF1
Meneuvonen, PJ1
Salvadori, B1
Gould, AB1
Kusla, J1
Luciak, M1
Gasiński, J1
Wilson, DR1
Skelton, FR1
Gunnells, CJ1
Stickel, DL1
Robinson, RR2
Frankhuyzen, AL1
Witter, A1
Balikian, H1
Brodie, A1
Willoughby, S1
Yoshinaga, H1
Chinn, RH1
Düsterdieck, GO1
Gleadle, RH1
Moeller, J1
Tsai, ZH1
Castiglioni, GC1
Gennari, R1
Dinç, I1
Barlas, O1
Chiappino, G1
Baroni, M1
Margolin, AH1
Stocks, LO1
Conn, J1
Simon, NM1
Bergan, JJ1
Baumber, JS1
Torres, M1
Manta, I2
Hodîrnău, A2
Băltescu, V2
Proinov, I2
Schneider, E2
Lloyd, IJ2
Kahuho, SK1
Mulimba, O1
Webala, GS1
Enger, E1
Arnesen, E1
Geddes, RA1
Pawsey, CG1
O'Halloran, MW1
Ludwig, RN1
Goldsmith, RF1
Starr, LM1
Gentle, JL3
Mani, MK1
Stewart, JH2
Nelson, J1
Schley, G1
Bock, KD2
Hocevar, V1
Merguet, P2
Rausch-Stroomann, JG2
Schröder, E2
Schümann, HJ2
Wells, S1
Silver, D1
Jacobsen, J1
Renner, D1
Stant, EG1
Brill, AB1
Biddle, CM1
Londe, S1
Robson, AM1
Goldring, D1
Barbi, G1
Giocoli, G1
Cavina, G1
Sardini, D1
Basiliere, J1
Newcomer, AD1
Marsen, B1
Dissmann, T1
Lohmann, FW1
Molzahn, M1
Bayard, F1
Beitins, IZ1
Lubash, GD1
Migeon, CJ2
Linshaw, M1
Cote, ML1
Fleisher, DS1
Ushkalov, AF1
Cocchieri, G1
Daniele, GM1
Reimold, EW1
McCoy, RM2
Fishman, L1
Rhamy, RK2
Scott, HW2
Creditor, MC1
Loschky, UK1
Imai, M1
Egdahl, RH1
Edwards, KD2
Russell, A1
Petri, G1
Julesz, M1
László, FA1
Durszt, F1
Troján, I1
George, JM1
Gillespie, L1
Chick, WT1
Helmer, OM1
Judson, WE1
Grandchamp, A1
Bierans de Haan, B1
Kavunets', GP1
Tsuchiyama, H1
Muto, Y1
Tokunaga, T1
Aramaki, T1
Birchall, R1
Batson, HM1
Piante, M1
Fanestil, DD1
Paar, D1
Young, JL1
Greene, AS1
Smith, BN1
Kiepenheuer, K1
Rhomberg, F1
Adlin, V1
Salti, IS1
Dickey, JM1
Kukharenko, AN1
Wilkins, RW1
Devaux, C1
Leroux-Robert, C1
Seriu, Y1
Wakabayashi, A1

Clinical Trials (116)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prevalence of Primary Aldosteronism in Patients With Stroke[NCT03789357]300 participants (Actual)Observational2018-05-01Completed
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Parallel-Group, Dose-Ranging Study to Evaluate the Efficacy and Safety of Multiple Dose Strengths of CIN-107 as Compared to Placebo After 12 Weeks of Treatment in Patients With Treatment-Resista[NCT04519658]Phase 2275 participants (Actual)Interventional2020-10-12Completed
Radiofrequency Ablation for Aldosterone-producting Adenoma in Patients With Primary Aldosteronism: Evaluation of the Blood Pressure Control and of Its Safety.[NCT02756754]31 participants (Actual)Interventional2016-11-07Completed
[NCT00000608]Phase 20 participants Interventional1997-02-28Completed
Electronic Alert-Based Computerized Decision Support to Improve Testing For Primary Aldosteronism in Patients With Hypertension: ALERT-PA[NCT05925569]1,600 participants (Anticipated)Interventional2023-12-31Not yet recruiting
Resident Doctor, Master Degree Candidate[NCT05991856]45 participants (Anticipated)Observational2020-01-01Recruiting
Preoperative Supine Time for Adrenal Venous Sampling: A Prospective Randomized Controlled Trial[NCT05658705]120 participants (Anticipated)Interventional2023-03-29Recruiting
Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension[NCT05593055]Phase 475 participants (Anticipated)Interventional2023-08-25Recruiting
Efficacy and Safety of Percutaneous Superselective Adrenal Arterial Embolization in the Treatment of Primary Aldosteronism With Bilateral Idiopathic Hyperaldosteronism: A Prospective Cohort Study[NCT05186675]50 participants (Anticipated)Interventional2022-01-01Enrolling by invitation
The Long-term Effect of Superselective Adrenal Arterial Embolization and Medical Treatment for Primary Aldosteronism on Cardiorenovascular Protection, Blood Pressure, and the Endocrinological Profile.[NCT05262660]400 participants (Anticipated)Observational [Patient Registry]2022-04-01Not yet recruiting
HyperAldosteronism in Pregnancy Predicted Impacts[NCT05636995]200 participants (Anticipated)Observational [Patient Registry]2023-01-10Recruiting
Glucose Metabolism in Subjects With Aldosterone-Producing Adenomas[NCT02362308]10 participants (Actual)Observational2015-01-31Completed
Effectiveness and Safety of Superselective Adrenal Arterial Embolization (SAAE) for Resistant Hypertension: A Randomized, Parallel, Controlled Clinical Trial[NCT05552300]144 participants (Anticipated)Interventional2022-10-01Not yet recruiting
Salt Sensitive Hypertension and Striatin[NCT03683069]Phase 4400 participants (Actual)Interventional2019-01-15Active, not recruiting
An Open-label, Prospective, Controlled Clinical Trial on Effects and Safety of Adrenal Artery Ablation (Triple A) for Primary Aldosteronism[NCT03398785]Phase 366 participants (Actual)Interventional2017-10-01Completed
African Prospective Study for the Early Detection and Identification of Cardiovascular Disease and Hypertension (African-PREDICT Study)[NCT03292094]1,202 participants (Actual)Observational2013-02-04Active, not recruiting
"The RADIANCE-HTN Study. A Study of the ReCor Medical Paradise System in Clinical Hypertension"[NCT02649426]292 participants (Anticipated)Interventional2016-03-31Active, not recruiting
Prospective Assessment of The Prevalence of Primary Aldosteronism in Hypertensive Patients Presenting With Atrial Flutter or Fibrillation[NCT01267747]411 participants (Actual)Observational2015-01-31Completed
CPAP Effect on Nocturnal Evolution of Chemosensitivity Determinants in Sleep Apnea-hypopnea Patients With Isolated Nocturnal Hypertension or Day-nigh Sustained Hypertension[NCT02398032]Phase 432 participants (Actual)Interventional2013-05-31Completed
Vascular Function Markers: Differences Between Lean and Abdominally Overweight / Obese Men and Effects of Weight Loss[NCT01675401]75 participants (Actual)Interventional2012-09-30Completed
Optimum Treatment for Drug-Resistant Hypertension[NCT02369081]Phase 4348 participants (Actual)Interventional2009-05-31Active, not recruiting
Effect of Mineralcorticoid Recept Antagonist on Cardiovascular Disease in Patients With Hypertension and Hyperaldosteronemia:A Multicenter Randomized Controlled Study[NCT05688579]Phase 48,000 participants (Anticipated)Interventional2023-04-16Enrolling by invitation
A Safety and Feasibility Study of Water-only Fasting and Refeeding for Treatment of Stage 1 and 2 Hypertensive Patients[NCT04515095]30 participants (Actual)Interventional2020-08-16Completed
Effects of Mineralocorticoid and AT-1 Receptor Antagonism on the Aldosterone-Renin Ratio (ARR) In Primary Aldosteronism Patients (EMIRA Study): Rationale and Design[NCT04185857]50 participants (Actual)Observational2018-01-01Completed
The Effect of Low Salt Diet on CKD Progression:A Randomized Controlled Trial[NCT05716386]200 participants (Actual)Interventional2023-02-28Completed
A Phase II, Randomized, Double-blind, Placebo Controlled, Multi-center Study to Evaluate the Effects of LCI699 on Cortisol in Patients With Hypertension[NCT00817414]Phase 263 participants (Actual)Interventional2009-01-14Completed
A Multi-center, Randomized, Double-blind, Placebo and Active Controlled, Parallel Group, Dose Finding Study to Evaluate the Efficacy and Safety of LCI699 Compared to Placebo After 8 Weeks Treatment in Patients With Essential Hypertension[NCT00758524]Phase 2628 participants (Actual)Interventional2008-09-11Completed
A Phase II, Randomized, Double-blind, Placebo and Active Controlled, Parallel Group, Multi-center, Dose Ranging Study to Evaluate the Efficacy and Safety of LCI699 Compared to Placebo After 8 Weeks Treatment in Patients With Resistant Hypertension[NCT00817635]Phase 2155 participants (Actual)Interventional2008-12-22Completed
A Pilot, Single-blind, Forced-titration Study to Assess the Hemodynamic and Hormonal Effects, Safety and Tolerability of the Aldosterone Synthase Inhibitor LCI699 in Patients With Primary Hyperaldosteronism[NCT00732771]Phase 212 participants (Anticipated)Interventional2008-06-30Completed
Southern Danish Hypertension and Diabetes Study (SDHDS) With Amiloride[NCT02122731]Phase 480 participants (Actual)Interventional2010-11-30Completed
Mineralocorticoid Receptor and Obesity Induced Cardiovascular Complications[NCT01406015]38 participants (Actual)Interventional2009-02-28Completed
Aldosterone and Glucose Homeostasis[NCT00732160]34 participants (Actual)Interventional2008-09-30Completed
Caveolin-1 and Vascular Dysfunction[NCT01426529]Phase 1120 participants (Anticipated)Interventional2010-10-01Active, not recruiting
Serum Levels of Advanced Glycation End-products After Dietary Intervention in Hypertensive Patients: Study Protocol of a Randomized Clinical Trial.[NCT02848677]Phase 2120 participants (Anticipated)Interventional2015-11-30Recruiting
Safety, Success Rate and Long Term Consequences of Renal Denervation in Patients With Therapy Resistant Hypertension. The Dutch National Renal Denervation Registry[NCT02482103]1,000 participants (Anticipated)Observational [Patient Registry]2013-04-30Recruiting
HALT Progression of Polycystic Kidney Disease Study B[NCT01885559]Phase 3486 participants (Actual)Interventional2006-01-31Completed
Characteristics Predicting Clinically Relevant Reduction of Hypertension Following Adrenalectomy for Primary Aldosteronism: a Multicenter Analysis[NCT04761354]514 participants (Actual)Observational2016-03-26Completed
LC-MS/MS-specific Cutoffs for Screening and Confirmatory Testing of Primary Aldosteronism: A Multi-center Study[NCT05959863]300 participants (Anticipated)Observational2023-08-30Recruiting
Increasing Stay-on-therapy in Hypertensive Patients Treated With First-line Diuretics: An Active Pharmacosurveillance and Pharmacogenetic Study.[NCT00408512]Phase 42,500 participants (Anticipated)Interventional2006-12-31Completed
Identification of New Biomarkers for the Classification and Monitoring of Difficult-to-treat Arterial Hypertension: Prospective Observational Study[NCT03034265]24 participants (Actual)Observational2016-05-31Completed
A 4-Week, Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Parallel Group Study To Evaluate The Safety, Tolerability And Efficacy Of Once Daily PF-04971729 And Hydrochlorothiazide In Patients With Type 2 Diabetes Mellitus With Inadequa[NCT01096667]Phase 2194 participants (Actual)Interventional2010-05-17Completed
Effect of Anti-hypertensive Medications on the Diagnostic Accuracy in Screening for Primary Aldosteronism:a Prospective Study[NCT04991961]330 participants (Anticipated)Observational2020-09-15Recruiting
Table Olives Nutritional Intervention: Pharmacokinetics of Polyphenols and Pentacyclic Triterpenes and Assessment of Antioxidant, Cardiovascular and Anti-inflammatory Biomarkers[NCT03886597]Phase 1/Phase 258 participants (Actual)Interventional2019-03-25Completed
Comparison of Atorvastatin and Pitavastatin on the Effect of HbA1c in Acute Myocardial Infarction (AMI) Patients With Abnormal Glucose Metabolism: a Multicenter Prospective Randomized Clinical Trial[NCT04945122]Phase 4900 participants (Anticipated)Interventional2015-10-01Recruiting
A Multi-center, Open-label, Randomized, 12-month, Parallel-group, Non-inferiority Study to Compare the Hemoglobin A1C Metabolism of Pitavastatin Therapy Versus Atorvastatin in Chinese Patients With Prediabetes and Hypertension[NCT03532620]Phase 4396 participants (Anticipated)Interventional2018-08-09Recruiting
Effect of Statin Use on Aldosterone Secretion[NCT02871687]Phase 1103 participants (Actual)Interventional2016-04-30Completed
Case Detection and Confirmation, Subtype Classification of Patients With Primary Aldosteronism[NCT02755519]300 participants (Actual)Observational2014-05-31Completed
Styrian Vitamin D Hypertension Trial: A Randomized, Double-blind, Placebo Controlled Trial to Evaluate the Effects of Vitamin D Supplementation on Systolic Ambulatory Blood Pressure in Vitamin D Deficient Hypertensive Patients[NCT02136771]Phase 4200 participants (Actual)Interventional2011-06-30Completed
68Ga-Pentixafor PET/CT for the Subtyping Diagnosis of Primary Aldosteronism: A Prospective Diagnostic Accuracy Study[NCT05131061]100 participants (Actual)Observational2021-11-11Completed
Hypertension in High School Students: Genetic and Environmental Factors[NCT06049641]2,638 participants (Actual)Observational2014-10-31Completed
Phase 4 Study of Losartan in Hypertensive Men and Women With Obstructive Sleep Apnea Before and After Continuous Positive Airway Pressure (CPAP) Treatment[NCT00701428]Phase 490 participants (Actual)Interventional2008-06-30Completed
Efficacy of Continuous Positive Airway Pressure (CPAP) on Blood Pressure Control of Resistant Hypertension Patients With Obstructive Sleep Apnea Syndrome (OSAS).[NCT01508754]Phase 4125 participants (Actual)Interventional2012-01-31Completed
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE): The Role of Angiotensin-(1-7) in Hypertension and Hypertension-Induced Heart and Kidney Damage[NCT04752293]125 participants (Anticipated)Observational2021-05-19Recruiting
Dietary Approaches to Stop Hypertension in 'Diastolic' Heart Failure 2 (DASH-DHF 2)[NCT01942395]18 participants (Actual)Interventional2012-09-18Terminated (stopped due to study diet is no longer available to match with the previous participants.)
Estudio RioplateNsE Sobre Telemonitoreo en hIpertensos No-controlAdos[NCT02730052]0 participants (Actual)Interventional2016-12-31Withdrawn (stopped due to Centers recruited poorly)
Aspirin AM or PM in Reduction of Tension: a Randomized Cross-over Trial[NCT01379079]Phase 4290 participants (Actual)Interventional2011-04-30Completed
Safety and Efficacy of Fludrocortisone Addition to Dexamethasone in the Management of Hospitalised COVID-19 Patients[NCT05453214]Phase 310 participants (Actual)Interventional2021-12-04Completed
Effect of Sodium Intake on Calcium Retention in Black and White Adolescent Girls.[NCT01564238]67 participants (Actual)Interventional1999-01-31Completed
DASH-Sodium Trial in Adolescents[NCT02993458]79 participants (Actual)Interventional2016-10-31Terminated (stopped due to safety risks to youth in the study required early termination of the study)
[NCT00917345]150 participants (Anticipated)Observational2008-01-31Recruiting
Towards Cost-effective Management of Patients With Hypertension Due to Primary Aldosteronism: Adrenal Vein Sampling or Ct-scan?[NCT01096654]Phase 3200 participants (Actual)Interventional2010-07-31Completed
Multicenter Study on Use and Interpretation of Adrenal Vein Sampling[NCT01234220]2,604 participants (Actual)Observational2010-05-31Completed
Prospective Cross-sectional Study on Prevalence of Primary Aldosteronism in Resistant Hypertension and Association With Cardiometabolic Complications[NCT04213963]100 participants (Anticipated)Observational2011-09-01Recruiting
A Double Blind, Dose Range, Placebo Controlled Study of the Effects of Rostafuroxin vs Placebo in Patients With Stable, Uncomplicated, Essential Hypertension.[NCT00415038]Phase 2438 participants (Actual)Interventional2005-02-28Completed
Macrolides for KCNJ5 - Mutated Aldosterone-Producing Adenoma (MAPA): A Study Of Personalized Diagnosis of Primary Aldosteronism With Implications For Treatment[NCT03414918]342 participants (Anticipated)Interventional2018-03-31Not yet recruiting
A Blinded Crossover Study of the 24 Hour Blood Pressure Response to Treatment of Obstructive Sleep Apnea Associated Hypertension With Nebivolol or Hydrochlorothiazide[NCT02710071]Phase 441 participants (Actual)Interventional2015-01-31Completed
A Placebo Controlled Double Blinded Crossover Study of the Antihypertensive Efficacy of Guanfacine vs Hydrochlorothiazide in Obstructive Sleep Apnea (OSA) Associated Hypertension[NCT02699125]Phase 441 participants (Actual)Interventional2015-01-31Completed
Genetic Based Analysis of Identifying Predictors of Blood Pressure Response in Hypertensive Patients After Renal Denervation[NCT04321044]300 participants (Actual)Interventional2019-01-01Active, not recruiting
Efficiency of Speech Therapy in Resistant Hypertensive Patients With Mild Obstructive Sleep Apnea Syndrome[NCT03753633]50 participants (Anticipated)Interventional2017-10-01Active, not recruiting
A 36-week, Randomized, Double-blind, Multi-center, Parallel Group Study Comparing the Efficacy and Safety of Aliskiren in Combination With Losartan Compared to Losartan on the Regression of Left Ventricular Hypertrophy in Overweight Patients With Essentia[NCT00219141]Phase 3460 participants (Actual)Interventional2005-10-31Completed
Lysine-specific Demethylase 1 and Salt-sensitivity in Humans[NCT03029806]88 participants (Anticipated)Interventional2017-01-02Active, not recruiting
Oral Sodium to Preserve Renal EfficiencY in Acute Heart Failure (OSPREY-AHF)[NCT04334668]70 participants (Actual)Interventional2020-05-20Active, not recruiting
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Essential Hypertension, During Basal Conditions and After Hypertonic Saline Infusion.[NCT00345124]50 participants (Actual)Interventional2006-05-31Completed
Technology Assisted Management of Uncontrolled Hypertension (TEAM-HTN): a Pilot Study[NCT03281772]180 participants (Anticipated)Observational2017-01-24Recruiting
Phase III, Single-Center, Open Label, Trial Evaluating the Safety and Efficacy of PectaSol-C Modified Citrus Pectin on PSA Kinetics in Prostate Cancer in the Setting of Serial Increases in PSA[NCT01681823]Phase 260 participants (Actual)Interventional2013-06-30Completed
The Pathophysiology and Treatment of Supine Hypertension in Patients With Autonomic Failure[NCT00223717]Phase 1152 participants (Actual)Interventional2001-01-31Completed
Anesthesiological Strategies in Elective Craniotomy: Randomized, Equivalence, Open Trial[NCT00741351]Phase 3411 participants (Actual)Interventional2007-12-31Completed
Comparison of the Analgesic Effects of Scalp Nerve Block and Intravenous Ibuprofen Applications Under the Guidance of Nociception Level Index (NoL) in Patients Undergoing Elective Supratentorial Craniotomy[NCT05763836]Phase 4102 participants (Anticipated)Interventional2022-11-01Recruiting
A Triple-Blind, Parallel Study to Investigate the Effect of Losartan Versus Atenolol on the Reduction of Morbidity and Mortality in Hypertensive Patients With Left Ventricular Hypertrophy[NCT00338260]Phase 3496 participants (Actual)Interventional1995-06-30Completed
Genetic Epidemiology of Responses to Antihypertensives[NCT00005520]1,200 participants (Actual)Observational1997-02-28Completed
The Prevalence and the Prognosis of Resistant Hypertension Ascertained With Systemic Investigation and Optimal Treatment With Antihypertensive Drugs[NCT01703780]9,638 participants (Actual)Observational2012-07-31Active, not recruiting
[NCT00005181]0 participants Observational2000-07-31Completed
Short-Term Oral Mifepristone for Central Serous Chorioretinopathy. A Placebo-controlled Dose Ranging Study of Mifepristone in the Treatment of CSC (STOMP-CSC)[NCT02354170]Phase 216 participants (Actual)Interventional2015-01-31Completed
Is Spironolactone Safe and Effective in the Treatment of Cardiovascular Disease in Mild Chronic Renal Failure?[NCT00291720]Phase 2120 participants (Actual)Interventional2005-04-30Completed
Randomized Trial of Spironolactone Versus Amiloride as an Add on Agent in Resistant Hypertension[NCT00709137]0 participants (Actual)Interventional2008-10-31Withdrawn (stopped due to lack of enrollment)
South Danish Hypertension and Diabetes Study[NCT01062763]Phase 3119 participants (Actual)Interventional2010-03-31Completed
Effects of Nebivolol Versus Metoprolol on Blood Flow Responses to Exercise and Angiotensin II in Hypertensive Patients[NCT01502787]Phase 446 participants (Actual)Interventional2009-04-30Completed
Aldosterone-Renin Ratio to Diagnose Primary Aldosteronism in a Population of Patients With Therapy-Resistant Hypertension: Test Characteristics, Diagnostic Value and Predictive Value for Antihypertensive Treatment. The Dutch ARRAT Study.[NCT00407784]500 participants Observational2007-01-31Recruiting
BNP Pharmacodynamics and Effects on Metabolism in Lean and Obese Subjects[NCT01977859]Phase 14 participants (Actual)Interventional2013-11-30Completed
Effect of Nesiritide Infusion on Insulin Sensitivity in Healthy Obese Insulin Resistant Subjects[NCT03234751]Phase 16 participants (Actual)Interventional2017-07-13Completed
Pilot Study to Assess Blockade of Calcium Channels and Sodium Chloride Cotransporters for Physiologic Abnormalities in Liver Transplant Associated Hypertension[NCT05275907]Phase 40 participants (Actual)Interventional2022-07-12Withdrawn (stopped due to Screened participants did not meet inclusion criteria prior to study completion date)
The Effectiveness of an Educational Intervention for Sodium Restriction in Patients With Hypertension: Study Protocol for a Randomized Controlled Trial[NCT02848690]120 participants (Anticipated)Interventional2015-11-30Recruiting
China Salt Substitute Study in Tibet: Efficacy of Salt Substitute in Reducing Blood Pressure in Hypertensive Adults[NCT01429246]282 participants (Actual)Interventional2009-02-28Completed
The Intra-Procedural Cortisol Assay During Adrenal Vein Sampling: Rationale andDesign of A Randomized Study (I-PADUA)[NCT03449797]200 participants (Anticipated)Interventional2018-04-01Not yet recruiting
Genes of Hypertension in African Americans[NCT00063505]5,000 participants (Actual)Observational2002-12-31Completed
Comparison of Saline Infusion Test, Captopril Challenge Test, and Oral Sodium Loading Test in the Diagnosis of Primary Aldosteronism[NCT04193137]200 participants (Actual)Observational2019-11-30Completed
Prospective Evaluation of Confirmatory Testing For Primary Aldosteronism[NCT04422756]200 participants (Anticipated)Observational2017-01-15Recruiting
Case Detection and Confirmation, Subtype Classification of Patients With Primary Aldosteronism[NCT03500120]200 participants (Actual)Observational2017-09-01Completed
The Role of Aldosterone on Sympathetic Nerve Activity and Insulin Sensitivity[NCT02102243]Phase 40 participants (Actual)Interventional2010-11-30Withdrawn (stopped due to No longer interested in study topic)
Usefulness of the Ipsilateral and Contralateral Index for the Interpretation of Adrenal Vein Sampling (AVS) in the Subtype Diagnosis of Primary Aldosteronism[NCT04378387]60 participants (Actual)Observational2005-01-01Completed
Randomized Double-Blind Placebo-Controlled Study of Pyrazinoylguanidine Hydrochloride (Amiloride) in Subjects With Coronary Artery Disease[NCT01228214]Phase 2/Phase 3100 participants (Actual)Interventional2011-03-31Active, not recruiting
[NCT00005138]0 participants Observational1976-06-30Completed
A Clinical Trial of Renin Profiling in Selection of Initial Antihypertensive Drug[NCT00834600]185 participants (Actual)Interventional2005-12-31Completed
The Function of Dopaminergic and Noradrenergic Systems in Salt-Sensitive Hypertension: The Effects of Changes in Sodium Intake[NCT00001176]110 participants Observational1981-05-31Completed
Autonomic Imbalance and 24-h Blood Pressure Change in Patients With Chronic Renal Disease[NCT00298129]278 participants (Actual)Observational2004-02-29Completed
Efficacy of L-arginine Treatment on Blood Pressure Control Patients With Stage 1 Hypertension[NCT02894723]Phase 440 participants (Anticipated)Interventional2016-09-30Not yet recruiting
Kidney Dopamine Effects on Urinary Sodium Excretion in Postural Tachycardia Syndrome[NCT00685919]Phase 2/Phase 332 participants (Actual)Interventional2008-05-31Completed
[NCT00005394]0 participants Observational1995-08-31Completed
LOVE-COARCT Study: Long-term Outcomes and Vascular Evaluation After Coarctation of the Aorta Treatment[NCT03262753]90 participants (Anticipated)Observational2013-06-01Recruiting
Resistant Hypertension On Treatment - Sequential Nephron Blockade Compared to Dual Blockade of the Renin-angiotensin-aldosterone System Plus Bisoprolol in the Treatment of Resistant Arterial Hypertension: A Randomized Trial (ResHypOT)[NCT02832973]Phase 472 participants (Actual)Interventional2015-09-30Completed
Renin System Responses to Combined Renin Inhibition and Beta Adrenergic Blockade[NCT00627861]1 participants (Actual)Interventional2008-11-30Terminated (stopped due to The renin laboratory used in the study is no longer available.)
Pilot Study of Cardiac Magnetic Resonance in Patients With Muscular Dystrophy[NCT02921321]100 participants (Anticipated)Observational2014-01-31Active, not recruiting
Randomized, Controlled Pilot Trial of Domperidone in Relapsing-Remitting Multiple Sclerosis[NCT02493049]Phase 217 participants (Actual)Interventional2015-08-31Completed
Addressing HyperteNsion and Diabetes Through Community-Engaged Systems in Puno, Peru (ANDES Study)[NCT05524987]1,068 participants (Anticipated)Interventional2022-11-30Not yet recruiting
[NCT00155064]Phase 4100 participants (Anticipated)Interventional2002-07-31Completed
Childhood Obesity: Variations in Management[NCT00160914]500 participants (Actual)Observational2001-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Mean Seated Diastolic BP (DBP)

(NCT04519658)
Timeframe: 12 weeks

InterventionmmHg (Mean)
mITT Population 0.5mg-9.1
mITT Population 1mg-11.7
mITT Population 2mg-14.0
mITT Population Placebo-9.3

Change From Baseline in Mean Seated Systolic BP (SBP)

(NCT04519658)
Timeframe: 12 weeks

InterventionmmHg (Mean)
mITT Population 0.5mg-12.4
mITT Population 1mg-17.3
mITT Population 2mg-19.2
mITT Population Placebo-9.8

The Percentage of Patients Achieving a Seated BP Response <130/80 mmHg

(NCT04519658)
Timeframe: 12 weeks

InterventionParticipants (Count of Participants)
mITT Population 0.5mg21
mITT Population 1mg28
mITT Population 2mg26
mITT Population Placebo21

Apparent Terminal Half-life (T1/2) of LCI699

(NCT00817414)
Timeframe: Days 7, 28: Pre-dose and 3 hours post-dose; Day 30: Pre-dose; Day 42: Pre-dose and 0.5, 1, 2, 3, 4, and 8-hours post-dose

Interventionhr (Geometric Mean)
Cohort A: LCI699 0.5 mg QD4.67
Cohort A: LCI699 1.0 mg QD3.79
Cohort B1: LCI699 1.0 mg BID5.52
Cohort B1: LCI699 2.0 mg QD4.90

Area Under the Concentration Time Curve From Time 0 to 8 Hours Post LCI699 Administration (AUC0-8)

(NCT00817414)
Timeframe: Day 42: Pre-dose and 0.5, 1, 2, 3, 4, and 8-hours post-dose

Interventionnanogram*hour per milliliter (ng*hr/mL) (Geometric Mean)
Cohort A: LCI699 0.5 mg QD6.60
Cohort A: LCI699 1.0 mg QD14.1
Cohort B1: LCI699 1.0 mg BID24.1
Cohort B1: LCI699 2.0 mg QD46.4

Area Under the Concentration Time Curve Over the Dosing Interval (AUC0-τ) for LCI699

(NCT00817414)
Timeframe: Days 7, 28: Pre-dose and 3 hours post-dose; Day 30: Pre-dose; Day 42: Pre-dose and 0.5, 1, 2, 3, 4, and 8-hours post-dose

Interventionng*hr/mL (Geometric Mean)
Cohort A: LCI699 0.5 mg QD9.23
Cohort A: LCI699 1.0 mg QD18.8
Cohort B1: LCI699 1.0 mg BID30.6
Cohort B1: LCI699 2.0 mg QD68.9

LCI699 Plasma Concentration Post LCI699 Administration at Day 7

(NCT00817414)
Timeframe: Predose and 3 hours post-dose on Day 7

Interventionnanogram per milliliter (ng/mL) (Geometric Mean)
Cohort A: LCI699 0.5 mg QD1.51
Cohort A: LCI699 1.0 mg QD2.88
Cohort B1: LCI699 1.0 mg BID3.92
Cohort B1: LCI699 2.0 mg QD6.73

Maximum Plasma Concentration (Cmax) of LCI699

(NCT00817414)
Timeframe: Days 7, 28: Pre-dose and 3 hours post-dose; Day 30: Pre-dose; Day 42: Pre-dose and 0.5, 1, 2, 3, 4, and 8-hours post-dose

Interventionng/mL (Geometric Mean)
Cohort A: LCI699 0.5 mg QD1.42
Cohort A: LCI699 1.0 mg QD2.94
Cohort B1: LCI699 1.0 mg BID4.62
Cohort B1: LCI699 2.0 mg QD8.86

Maximum Tolerated Dose (MTD) of LCI699 With Respect to Effect on the Adrenocorticotropic Hormone (ACTH)-Stimulated Cortisol Response Following ACTH Stimulation in Hypertensive Participants

As per the protocol, MTD is the dose at which 4 participants exhibited ACTH-stimulated cortisol results <400 nanomoles per liter (nmol/L). The change in the distribution across the treatments were analyzed using 1- way analysis of variance (ANOVA) for continuous variables. (NCT00817414)
Timeframe: Up to Week 6

Interventionmilligrams (mg) (Number)
LCI6991.30

Number of Participants With Adverse Event (AEs)

An AE is an adverse medical event which occurs in a participant of the study and which is not necessarily in a causal relationship with the treatment the participant receives. (NCT00817414)
Timeframe: Up to 8 weeks

InterventionParticipants (Count of Participants)
Cohort A: LCI699 0.5 mg QD6
Cohort A: LCI699 1 mg QD9
Cohort B1: LCI699 1 mg BID10
Cohort B1: LCI699 2 mg QD10
Placebo10

Time of Maximum Plasma Concentration (Tmax) of LCI699

(NCT00817414)
Timeframe: Days 7, 28: Pre-dose and 3 hours post-dose; Day 30: Pre-dose; Day 42: Pre-dose and 0.5, 1, 2, 3, 4, and 8-hours post-dose

Interventionhour (hr) (Median)
Cohort A: LCI699 0.5 mg QD2.21
Cohort A: LCI699 1.0 mg QD1.00
Cohort B1: LCI699 1.0 mg BID1.00
Cohort B1: LCI699 2.0 mg QD1.00

LCI699 Exposure-response Relationship on Cortisol Levels Following ACTH Stimulation in Hypertensive Participants

Exposure-response relationship was assessed using ACTH stimulation test. Tests were done 2 hours after study drug administration (i.e., at peak LCI699 concentrations). An increase in cortisol greater than >500 nmol at 60 minutes after ACTH administration was expected. (NCT00817414)
Timeframe: Up to Week 6

,,,,
Interventionnanomoles per liter (nmol/L) (Mean)
Day 7Day 28Day 42
Cohort A: LCI699 0.5 mg QD690.0634.87647.51
Cohort A: LCI699 1.0 mg QD669.40573.41626.08
Cohort B1: LCI699 1.0 mg BID625.06554.79539.68
Cohort B1: LCI699 2.0 mg QD562.04539.09479.91
Placebo799.06804.86812.91

Percentage of Participants With a Mean Sitting Diastolic Blood Pressure (MSDBP) Response and MSDBP Control at Week 6 LOCF, as Measured by OBP

Automated arterial BP determinations was made with an automated BP device (such as the Omron BP monitor) in accordance with the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV. Sitting and standing BP and HR measurements were performed. MSDBP response was defined as the percentage of participants with a MSDBP <90 mmHg or a >= 10 mmHg reduction from baseline. MSDBP control was defined as the percentage of participants with a MSDBP <90 mmHg for non-diabetic participants and <80mHg for diabetic participants. (NCT00817414)
Timeframe: Week 6

,,,,
Interventionpercentage of participants (Number)
MSDBP ResponseMSDBP Control
Cohort A: LCI699 0.5 mg QD58.358.3
Cohort A: LCI699 1 mg QD66.766.7
Cohort B1: LCI699 1 mg BID10076.9
Cohort B1: LCI699 2 mg QD76.976.9
Placebo61.546.2

Percentage of Participants With a Mean Sitting Systolic Blood Pressure (MSSBP) Response and MSSBP Control at Week 6 Last Observation Carried Forward (LOCF), as Measured by Office Blood Pressure (OBP)

Automated arterial BP determinations was made with an automated BP device (such as the Omron BP monitor) in accordance with the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV. Sitting and standing blood pressure (BP) and heart rate (HR) measurements were performed. MSSBP response was defined as the percentage of participants with a MSSBP <140 mmHg or a >=20 mmHg reduction from baseline. MSSBP control was defined as the percentage of participants with a MSSBP <140 mmHg for non-diabetic participants and <130mHg for diabetic participants. (NCT00817414)
Timeframe: Week 6

,,,,
Interventionpercentage of participants (Number)
MSSBP ResponseMSSBP Control
Cohort A: LCI699 0.5 mg QD58.350.0
Cohort A: LCI699 1 mg QD50.041.7
Cohort B1: LCI699 1 mg BID69.261.5
Cohort B1: LCI699 2 mg QD76.976.9
Placebo61.553.8

Core Period: Change From Baseline in Mean 24 Hour Ambulatory DBP at Week 8, as Measured by ABPM

An ABPM measured a participant's BP over a 24-hour period readings using an automated validated monitoring device from Baseline to Week 8. The 24-hour DBP was calculated by taking the mean of all ambulatory DBP readings for the 24-hour period. (NCT00758524)
Timeframe: Baseline, Week 8

Interventionmm Hg (Least Squares Mean)
Core Period: LCI699 0.25 mg QD-4.03
Core Period: LCI699 0.5 mg QD-2.44
Core Period: LCI699 1.0 mg QD-4.96
Core Period: LCI699 0.5 mg BID-2.75
Core Period: Eplerenone 50 mg BID-6.03
Core Period: Placebo1.03

Core Period: Change From Baseline in Mean 24 Hour Ambulatory SBP at Week 8 as Measured by Ambulatory Blood Pressure Monitoring (ABPM)

An ABPM measured a participant's BP over a 24-hour period readings using an automated validated monitoring device from Baseline to Week 8. The 24-hour SBP was calculated by taking the mean of all ambulatory SBP readings for the 24-hour period. (NCT00758524)
Timeframe: Baseline, Week 8

Interventionmm Hg (Least Squares Mean)
Core Period: LCI699 0.25 mg QD-7.15
Core Period: LCI699 0.5 mg QD-4.90
Core Period: LCI699 1.0 mg QD-7.73
Core Period: LCI699 0.5 mg BID-6.18
Core Period: Eplerenone 50 mg BID-10.52
Core Period: Placebo1.11

Core Period: Change From Baseline in Mean Sitting Diastolic Blood Pressure (MSDBP) at Week 8 Last Observation Carried Forward (LOCF), as Measured by Office Blood Pressure (OBP)

Automated arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV, using an automated BP device (such as the Omron BP monitor). The change in the MSDBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from baseline in MSDBP was analyzed using an analysis of covariance model (ANCOVA) with treatment and region as factors and baseline MSDBP level as a covariate. (NCT00758524)
Timeframe: Baseline, Week 8

Interventionmm Hg (Mean)
Core Period: LCI699 0.25 mg QD-4.47
Core Period: LCI699 0.5 mg QD-5.50
Core Period: LCI699 1.0 mg QD-7.11
Core Period: LCI699 0.5 mg BID-4.25
Core Period: Eplerenone 50 mg BID-7.49
Core Period: Placebo-3.22

Core Period: Change From Baseline in Mean Sitting Systolic Blood Pressure (MSSBP) at Week 8 LOCF, as Measured by OBP

Automated arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV, using an automated BP device (such as the Omron BP monitor). The change in the MSSBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from baseline in MSSBP was analyzed using an ANCOVA with treatment and region as factors and baseline MSSBP levels as a covariate. (NCT00758524)
Timeframe: Baseline, Week 8

Interventionmm Hg (Mean)
Core Period: LCI699 0.25 mg QD-9.00
Core Period: LCI699 0.5 mg QD-10.69
Core Period: LCI699 1.0 mg QD-11.93
Core Period: LCI699 0.5 mg BID-9.10
Core Period: Eplerenone 50 mg BID-13.31
Core Period: Placebo-2.93

Core Period: Change From Baseline in Plasma Aldosterone Levels at Week 8

Change from baseline was analyzed using plasma aldosterone values measured at Baseline and Week 8. (NCT00758524)
Timeframe: Baseline, Week 8

Interventionpicomoles per liter (pmol/L) (Mean)
Core Period: LCI699 0.25 mg QD-21.5
Core Period: LCI699 0.5 mg QD-20.0
Core Period: LCI699 1.0 mg QD-9.9
Core Period: LCI699 0.5 mg BID-47.5
Core Period: Eplerenone 50 mg BID277.1
Core Period: Placebo-28.8

Core Period: Change From Baseline in Plasma Cortisol Levels by Adrenocorticotropic Hormone (ACTH) Stimulation Test

The ACTH stimulation cortisol test was a standard procedure to measure the ability of adrenal cortex to respond to exogenous ACTH and directly assess the adrenal reserve. Serum cortisol concentrations at 1 hour after injection were measured to assess the maximum stimulated cortisol level achieved. Potential adrenal suppression was indicated if the serum cortisol concentration was <500 nanomoles per liter (nmol/L) at 1 hour after the injection. (NCT00758524)
Timeframe: Baseline, 1 hour post-dose at Week 8

Interventionnanomoles per liter (nmol/L) (Mean)
Core Period: LCI699 0.25 mg QD729.20
Core Period: LCI699 0.5 mg QD692.74
Core Period: LCI699 1.0 mg QD604.46
Core Period: LCI699 0.5 mg BID609.21
Core Period: Eplerenone 50 mg BID802.32
Core Period: Placebo822.65

Core Period: Dose Response Relationship of LCI699 as Measured by Change From Baseline in MSDBP at Week 8

Automated arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV, using an automated BP device (such as the Omron BP monitor). The change in the MSDBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from baseline in MSDBP was analyzed using an analysis of covariance model (ANCOVA) with treatment and region as factors and baseline MSDBP level as a covariate. (NCT00758524)
Timeframe: Baseline, Week 8

Interventionmm Hg (Mean)
Core Period: LCI699 0.25 mg QD-4.47
Core Period: LCI699 0.5 mg QD-5.50
Core Period: LCI699 1.0 mg QD-7.11
Core Period: LCI699 0.5 mg BID-4.25

Core Period: Dose Response Relationship of LCI699 as Measured by Change From Baseline in MSSBP at Week 8

Automated arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV, using an automated BP device (such as the Omron BP monitor). The change in the MSSBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from baseline in MSSBP was analyzed using an ANCOVA with treatment and region as factors and baseline MSSBP levels as a covariate. (NCT00758524)
Timeframe: Baseline, Week 8

Interventionmm Hg (Mean)
Core Period: LCI699 0.25 mg QD-9.00
Core Period: LCI699 0.5 mg QD-10.69
Core Period: LCI699 1.0 mg QD-11.93
Core Period: LCI699 0.5 mg BID-9.10

Withdrawal Period: Change From Week 8 to Week 9 in MSDBP at Week 9, as Measured by OBP

Automated arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV, using an automated BP device (such as the Omron BP monitor). The change in the MSDBP was calculated comparing the Week 9 readings to the readings taken at Week 8 (Baseline). The change from Week 8 to week 9 in MSDBP was analyzed using an ANCOVA with treatment and region as factors and Week 8 MSDBP level as a covariate. (NCT00758524)
Timeframe: From Week 8 to Week 9

Interventionmm Hg (Least Squares Mean)
Withdrawal Period: LCI699 0.25 mg QD0.5
Withdrawal Period: LCI699 0.25 mg QD Placebo0.5
Withdrawal Period: LCI699 0.5 mg QD1.6
Withdrawal Period: LCI699 0.5 mg QD Placebo-0.2
Withdrawal Period: LCI699 1.0 mg QD-0.5
Withdrawal Period: LCI699 1.0 mg QD Placebo2.5
Withdrawal Period: LCI699 0.5 mg BID1.3
Withdrawal Period: LCI699 0.5 mg BID Placebo1.3
Withdrawal Period: Eplerenone 50 mg BID-1.2
Withdrawal Period: Eplerenone 50 mg BID Placebo0.4
Withdrawal Period: Placebo1.6

Withdrawal Period: Change From Week 8 to Week 9 in MSSBP at Week 9 as Measured by OBP

Automated arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the Guidelines for management of hypertension: report of the 4th working party of the British Hypertension Society, 2004-BHS IV, using an automated BP device (such as the Omron BP monitor). The change in the MSSBP was calculated comparing the Week 9 readings to the readings taken at Week 8 (Baseline). The change from Week 8 to week 9 in MSSBP was analyzed using an ANCOVA with treatment and region as factors and Week 8 MSSBP level as a covariate. (NCT00758524)
Timeframe: From Week 8 to Week 9

Interventionmm Hg (Least Squares Mean)
Withdrawal Period: LCI699 0.25 mg QD0.3
Withdrawal Period: LCI699 0.25 mg QD Placebo3.3
Withdrawal Period: LCI699 0.5 mg QD0.5
Withdrawal Period: LCI699 0.5 mg QD Placebo2.5
Withdrawal Period: LCI699 1.0 mg QD0.4
Withdrawal Period: LCI699 1.0 mg QD Placebo5.3
Withdrawal Period: LCI699 0.5 mg BID1.6
Withdrawal Period: LCI699 0.5 mg BID Placebo4.4
Withdrawal Period: Eplerenone 50 mg BID-1.5
Withdrawal Period: Eplerenone 50 mg BID Placebo2.7
Withdrawal Period: Placebo1.8

Core Period: Number of Participants With Adverse Event (AEs), Serious Adverse Events (SAEs), and Deaths

An AE was an adverse medical event which occurs in a participant of the study and which is not necessarily in a causal relationship with the treatment the participant receives. SAEs were AEs leading to death, are life-threatening, require hospitalizations or prolongation of hospitalizations, represent an innate malformation or a congenital abnormality. (NCT00758524)
Timeframe: AEs: From start of the study drug treatment up to 8 weeks; SAE: From signing of the informed consent up to 8 weeks

,,,,,
InterventionParticipants (Count of Participants)
AEsSAEsDeaths
Core Period: Eplerenone 50 mg BID2600
Core Period: LCI699 0.25 mg QD2310
Core Period: LCI699 0.5 mg BID2700
Core Period: LCI699 0.5 mg QD2200
Core Period: LCI699 1.0 mg QD2400
Core Period: Placebo2310

Core Period: Percentage of Participants With a MSDBP Response and MSDBP Control at Week 8 LOCF

MSDBP response was defined as the percentage of participants with a MSDBP <90 mmHg or a >=10 mmHg reduction from Baseline. MSDBP control was defined as the percentage of participants with a MSDBP <90 mmHg. (NCT00758524)
Timeframe: Baseline, Week 8

,,,,,
Interventionpercentage of participants (Number)
MSDBP ResponseMSDBP Control
Core Period: Eplerenone 50 mg BID48.845.2
Core Period: LCI699 0.25 mg QD39.132.6
Core Period: LCI699 0.5 mg BID34.429.2
Core Period: LCI699 0.5 mg QD34.129.4
Core Period: LCI699 1.0 mg QD50.041.9
Core Period: Placebo27.618.4

Core Period: Percentage of Participants With a MSSBP Response and MSSBP Control at Week 8 LOCF

MSSBP response was defined as the percentage of participants with a MSSBP <140 mmHg or a >=20 mmHg reduction from baseline reduction from baseline. MSSBP control was defined as the percentage of participants with a MSSBP <140 mmHg. (NCT00758524)
Timeframe: Baseline, Week 8

,,,,,
Interventionpercentage of participants (Number)
MSSBP ResponseMSSBP Control
Core Period: Eplerenone 50 mg BID52.444.0
Core Period: LCI699 0.25 mg QD39.131.5
Core Period: LCI699 0.5 mg BID34.425.0
Core Period: LCI699 0.5 mg QD37.627.1
Core Period: LCI699 1.0 mg QD48.840.7
Core Period: Placebo17.115.8

Core Period: Trough to Hour Ratio for Change From Baseline in 24-hour Mean Ambulatory DBP at Week 8

Trough to peak ratios were derived from an ANCOVA model containing treatment, region, hour, treatment by hour interaction as factors with Baseline as a covariate. (NCT00758524)
Timeframe: Baseline, every hour up to 24 hours post-dose at Week 8

,,,,,
Interventionratio (Least Squares Mean)
Week 8, Hour 1Week 8, Hour 2Week 8, Hour 3Week 8, Hour 4Week 8, Hour 5Week 8, Hour 6Week 8, Hour 7Week 8, Hour 8Week 8, Hour 9Week 8, Hour 10Week 8, Hour 11Week 8, Hour 12Week 8, Hour 13Week 8, Hour 14Week 8, Hour 15Week 8, Hour 16Week 8, Hour 17Week 8, Hour 18Week 8, Hour 19Week 8, Hour 20Week 8, Hour 21Week 8, Hour 22Week 8, Hour 23Week 8, Hour 24
Core Period: Eplerenone 50 mg BID0.17-1.65-2.42-1.39-2.91-4.86-3.70-2.30-2.81-2.43-1.93-3.20-5.35-7.64-9.03-12.55-12.88-13.49-10.13-10.47-10.51-7.60-5.54-2.78
Core Period: LCI699 0.25 mg QD3.911.441.160.511.11-1.18-1.85-3.01-1.24-0.59-1.02-1.60-4.32-6.47-8.34-8.92-10.26-10.68-10.13-10.73-9.31-7.90-4.94-0.21
Core Period: LCI699 0.5 mg BID3.873.444.012.641.451.201.212.093.270.491.54-1.06-1.45-2.96-6.10-9.54-10.38-11.85-10.78-10.49-8.22-6.35-2.671.36
Core Period: LCI699 0.5 mg QD2.951.851.132.91-0.02-2.36-0.95-1.38-0.072.601.722.53-1.20-3.29-5.82-8.37-10.99-11.73-10.12-8.06-7.68-4.93-1.931.45
Core Period: LCI699 1.0 mg QD0.270.17-0.360.35-1.69-3.01-2.63-2.43-2.25-1.65-1.54-3.10-5.31-7.38-8.89-10.50-12.71-11.88-9.74-10.43-9.66-5.37-1.180.29
Core Period: Placebo7.116.284.997.024.311.823.622.653.303.862.383.241.52-0.90-1.01-1.61-4.20-6.89-5.84-5.21-4.12-1.091.821.98

Core Period: Trough to Hour Ratio for Change From Baseline in 24-hour Mean Ambulatory SBP at Week 8

Trough to peak ratios were derived from an ANCOVA model containing treatment, region, hour, treatment by hour interaction as factors with Baseline as a covariate. (NCT00758524)
Timeframe: Baseline, every hour up to 24 hours post-dose at Week 8

,,,,,
Interventionratio (Least Squares Mean)
Week 8, Hour 1Week 8, Hour 2Week 8, Hour 3Week 8, Hour 4Week 8, Hour 5Week 8, Hour 6Week 8, Hour 7Week 8, Hour 8Week 8, Hour 9Week 8, Hour 10Week 8, Hour 11Week 8, Hour 12Week 8, Hour 13Week 8, Hour 14Week 8, Hour 15Week 8, Hour 16Week 8, Hour 17Week 8, Hour 18Week 8, Hour 19Week 8, Hour 20Week 8, Hour 21Week 8, Hour 22Week 8, Hour 23Week 8, Hour 24
Core Period: Eplerenone 50 mg BID-5.33-5.90-5.89-5.12-7.22-7.91-8.70-8.06-7.46-7.35-5.75-6.25-8.81-10.91-12.04-16.68-19.59-18.55-15.49-16.09-15.34-12.47-9.02-8.90
Core Period: LCI699 0.25 mg QD-0.54-1.59-2.11-2.06-4.29-4.21-4.95-5.28-3.98-3.69-2.47-5.19-6.45-7.37-10.61-11.71-13.71-14.49-13.78-13.92-14.33-13.46-7.88-3.16
Core Period: LCI699 0.5 mg BID-1.42-0.570.911.50-1.70-1.02-0.76-3.02-1.87-1.73-1.74-3.92-4.05-6.12-9.78-13.03-13.72-15.60-15.93-15.47-13.63-10.55-6.73-3.76
Core Period: LCI699 0.5 mg QD0.090.15-1.53-1.18-3.09-3.12-2.10-4.69-1.59-0.30-0.430.73-2.30-5.68-8.28-10.01-11.96-14.37-13.08-13.22-10.06-8.35-6.23-0.64
Core Period: LCI699 1.0 mg QD-4.51-3.56-4.86-4.15-3.47-5.88-5.40-5.30-4.78-3.40-4.22-4.35-7.25-9.33-11.26-12.63-15.46-14.54-12.85-12.54-12.78-7.52-5.77-3.45
Core Period: Placebo8.236.484.604.682.781.422.253.762.392.543.514.693.200.750.02-0.33-3.03-6.35-6.98-6.53-3.89-0.942.180.70

Change From Baseline in MSDBP at Week 8 LOCF

Arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the American Heart Association guidelines using a calibrated standard aneroid or mercury sphygmomanometer or a calibrated standard sphygmomanometer. The change in the MSDBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from Baseline in MSDBP was analyzed using an ANCOVA with treatment and country as factors and Baseline MSDBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 8

InterventionmmHg (Mean)
LCI699 0.25 mg BID-4.5
LCI699 1 mg QD-6.0
LCI699 0.5 mg Followed by LCI699 1 mg BID-6.1
Eplerenone 50 mg BID-7.7
Placebo-4.8

Change From Baseline in MSSBP at Week 8 Last Observation Carried Forward (LOCF)

Arterial blood pressure (BP) determinations were made after the participant was in the sitting position for 5 minutes according to the American Heart Association guidelines using a calibrated standard aneroid or mercury sphygmomanometer or a calibrated standard sphygmomanometer. The change in the MSSBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from Baseline in MSSBP was analyzed using an analysis of covariance model (ANCOVA) with treatment and country as factors and Baseline MSSBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 8

InterventionmmHg (Mean)
LCI699 0.25 mg BID-11.4
LCI699 1 mg QD-13.1
LCI699 0.5 mg Followed by LCI699 1 mg BID-12.5
Eplerenone 50 mg BID-18.7
Placebo-8.8

Dose/Exposure BP Response Relationship of LCI699, as Measured by Change From Baseline in MSDBP at Week 8

Arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the American Heart Association guidelines using a calibrated standard aneroid or mercury sphygmomanometer or a calibrated standard sphygmomanometer. The change in the MSDBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from Baseline in MSDBP was analyzed using an ANCOVA with treatment and country as factors and Baseline MSDBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 8

InterventionmmHg (Mean)
LCI699 0.25 mg BID-4.5
LCI699 1 mg QD-6.0
LCI699 0.5 mg Followed by LCI699 1 mg BID-6.1

Dose/Exposure BP Response Relationship of LCI699, as Measured by Change From Baseline in MSSBP at Week 8

Arterial BP determinations were made after the participant was in the sitting position for 5 minutes according to the American Heart Association guidelines using a calibrated standard aneroid or mercury sphygmomanometer or a calibrated standard sphygmomanometer. The change in the MSSBP was calculated comparing the Week 8 readings to the readings taken at Baseline. The change from Baseline in MSSBP was analyzed using an ANCOVA with treatment and country as factors and Baseline MSSBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 8

InterventionmmHg (Mean)
LCI699 0.25 mg BID-11.4
LCI699 1 mg QD-13.1
LCI699 0.5 mg Followed by LCI699 1 mg BID-12.5

Number of Participants With Cortisol Levels Below 500 Nmol/L at 1 Hour After Adrenocorticotropic Hormone (ACTH) Injection at Week 8

Serum cortisol concentrations at 1 hour after injection were measured to assess the maximum stimulated cortisol level achieved. Potential adrenal suppression was indicated if the serum cortisol concentration was <500 nanomoles per liter (nmol/L) at 1 hour after the injection. (NCT00817635)
Timeframe: 1-hour post-dose at Week 8

InterventionParticipants (Count of Participants)
LCI699 0.25 mg BID0
LCI699 1 mg QD1
LCI699 0.5 mg Followed by LCI699 1 mg BID4
Eplerenone 50 mg BID0
Placebo0

Percent Change From Baseline in RAAS Biomarker: Active Renin (ARC) in LCI699 Compared to Eplerenone 50mg at Week 8 LOCF

Percent change from Baseline was analyzed by ANCOVA model using active renin values measured at Baseline and Week 8 LOCF, with treatment and country as factors and Baseline value as the covariate. Negative percent change from Baseline shows improvement. (NCT00817635)
Timeframe: Baseline, Week 8

Interventionpercent change in ARC (Geometric Least Squares Mean)
LCI699 0.25 mg BID73.1
LCI699 1 mg QD72.8
LCI699 0.5 mg Followed by LCI699 1 mg BID156.4
Eplerenone 50 mg BID430.6

Percent Change From Baseline in RAAS Biomarker: Plasma Renin Activity (PRA) in LCI699 Compared to Eplerenone 50mg at Week 8 LOCF

Percent change from Baseline was analyzed by ANCOVA model using plasma renin values measured at Baseline and Week 8 LOCF, with treatment and country as factors and Baseline value as the covariate. Negative percent change from Baseline shows improvement. (NCT00817635)
Timeframe: Baseline, Week 8

Interventionpercent change in PRA (Geometric Least Squares Mean)
LCI699 0.25 mg BID41.6
LCI699 1 mg QD74.3
LCI699 0.5 mg Followed by LCI699 1 mg BID107.7
Eplerenone 50 mg BID414.1

Percent Change From Baseline in RAAS Biomarker: Ratio of PA to PRA in LCI699 Compared to Eplerenone 50mg at Week 8 LOCF

Percent change from Baseline was analyzed by ANCOVA model using percent ratio of PA to PRA values measured at Baseline and Week 8 LOCF, with treatment and country as factors and Baseline value as the covariate. Negative percent change from Baseline shows improvement. (NCT00817635)
Timeframe: Baseline, Week 8

Interventionpercent change in ratio of PA to PRA (Geometric Least Squares Mean)
LCI699 0.25 mg BID-46.7
LCI699 1 mg QD-50.0
LCI699 0.5 mg Followed by LCI699 1 mg BID-78.3
Eplerenone 50 mg BID-57.1

Percent Change From Baseline in Renin-Angiotensin-Aldosterone-System (RAAS) Biomarker: Plasma Aldosterone (PA) in LCI699 Compared to Eplerenone 50 mg at Week 8 LOCF

Percent change from Baseline was analyzed by ANCOVA model using PA values measured at Baseline and Week 8 LOCF, with treatment and country as factors and Baseline value as the covariate. Negative percent change from Baseline shows improvement. (NCT00817635)
Timeframe: Baseline, Week 8

Interventionpercent change in aldosterone (Geometric Least Squares Mean)
LCI699 0.25 mg BID-22.3
LCI699 1 mg QD-30.4
LCI699 0.5 mg Followed by LCI699 1 mg BID-53.1
Eplerenone 50 mg BID115.0

Change From Baseline in Mean 24 Hours, Mean Daytime and Mean Nighttime DBP in LCI699 1mg QD Versus LCI699 0.5mg BID Arm at Week 4, as Measured by ABPM

An ABPM measured a participant's blood pressure over a 24-hour period including daytime and nighttime readings using an automated validated monitoring device from Baseline to Week 4. The 24-hour DBP was calculated by taking the mean of all ambulatory diastolic blood pressure readings for the 24-hour period. The change from Baseline in DBP was analyzed using an ANCOVA with treatment and country as factors and Baseline MSDBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 4

,
InterventionmmHg (Mean)
24-hour Mean DBPDaytime Mean DBPNighttime Mean DBP
LCI699 0.5 mg BID-2.5-2.6-2.8
LCI699 1 mg QD-4.3-3.9-4.5

Change From Baseline in Mean 24 Hours, Mean Daytime and Mean Nighttime Diastolic Blood Pressure (DBP) at Week 8 LOCF, as Measured by ABPM

An ABPM measured a participant's blood pressure over a 24-hour period including daytime and nighttime readings, using an automated validated monitoring device from Baseline to Week 8. The 24-hour DBP was calculated by taking the mean of all ambulatory diastolic blood pressure readings for the 24-hour period. The change from Baseline in DBP was analyzed using an ANCOVA with treatment and country as factors and Baseline MSDBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 8

,,,,
InterventionmmHg (Mean)
24-hour Mean DBPDaytime Mean DBPNighttime Mean DBP
Eplerenone 50 mg BID-9.6-9.5-9.6
LCI699 0.25 mg BID1.00.61.9
LCI699 0.5 mg Followed by LCI699 1 mg BID-3.7-3.4-4.6
LCI699 1 mg QD-3.4-3.6-2.5
Placebo-0.2-0.81.2

Change From Baseline in Mean 24 Hours, Mean Daytime and Mean Nighttime SBP in LCI699 1mg QD Versus LCI699 0.5mg BID Arm at Week 4, as Measured by ABPM

An ABPM measured a participant's blood pressure over a 24-hour period including daytime and nighttime readings using an automated validated monitoring device from Baseline to Week 4. The 24-hour SBP was calculated by taking the mean of all ambulatory systolic blood pressure readings for the 24-hour period. The change from Baseline in SBP was analyzed using an ANCOVA with treatment and country as factors and Baseline MSDBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 4

,
InterventionmmHg (Mean)
24-hour Mean SBPDaytime Mean SBPNighttime Mean SBP
LCI699 0.5 mg BID-4.7-5.3-4.5
LCI699 1 mg QD-7.8-8.1-6.8

Change From Baseline in Mean 24 Hours, Mean Daytime and Mean Nighttime Systolic Blood Pressure (SBP) at Week 8 LOCF, as Measured by Ambulatory Blood Pressure Measurement (ABPM)

An ABPM measured a participant's blood pressure over a 24-hour period including daytime and nighttime readings, using an automated validated monitoring device from Baseline to Week 8. The 24-hour SBP was calculated by taking the mean of all ambulatory systolic blood pressure readings for the 24-hour period. The change from Baseline in SBP was analyzed using ANCOVA with treatment and country as factors and Baseline MSSBP as a covariate. (NCT00817635)
Timeframe: Baseline, Week 8

,,,,
InterventionmmHg (Mean)
24-hour Mean SBPDaytime Mean SBPNighttime Mean SBP
Eplerenone 50 mg BID-15.7-15.7-15.4
LCI699 0.25 mg BID-4.4-4.9-3.2
LCI699 0.5 mg Followed by LCI699 1 mg BID-6.3-6.3-7.0
LCI699 1 mg QD-5.7-6.0-4.8
Placebo-1.0-1.60.4

Number of Participants With Adverse Event (AEs), Serious Adverse Events (SAEs), Hyperkalemia, and Hyponatremia

An AE was an adverse medical event which occurs in a participant of the study and which is not necessarily in a causal relationship with the treatment the participant receives. SAEs were AEs leading to death, are life-threatening, require hospitalizations or prolongation of hospitalizations, represent an innate malformation or a congenital abnormality. Hyperkalemia was defined as potassium level >5.5 millimoles per liter (mmol/L). It is the medical term that describes a potassium level that's higher than normal. Hyponatremia was defined as sodium level <135 mmol/L. It is the medical term that describes a sodium level that's lesser than normal. (NCT00817635)
Timeframe: AEs, Hyperkalemia, and Hyponatremia: From start of the study drug treatment up to 10 weeks; SAE: From signing of the informed consent up to 10 weeks

,,,,
InterventionParticipants (Count of Participants)
AE(s)SAE(s)Hyperkalemia [potassium level >5.5 mmol/L]Hyperkalemia [potassium level ≥6.0 mmol/L]Hyponatremia [sodium level <130 and ≥125 mmol/L]Hyponatremia [sodium level <135 mmol/L and ≥130mmol/L]
Eplerenone 50 mg BID1310013
LCI699 0.25 mg BID1502203
LCI699 0.5 mg Followed by LCI699 1 mg BID800007
LCI699 1 mg QD1500002
Placebo1601002

Percentage of Participants With a MSDBP Response and MSDBP Control at Week 8, as Measured by OBP

MSDBP response was defined as the percentage of participants with a MSDBP <90 mmHg or a >=10 mmHg reduction from baseline. MSDBP control was defined as the percentage of participants with a MSDBP <90 mmHg for non-diabetic participants and <80mHg for diabetic participants. (NCT00817635)
Timeframe: Week 8

,,,,
Interventionpercentage of participants (Number)
MSDBP ResponseMSDBP Control
Eplerenone 50 mg BID71.956.3
LCI699 0.25 mg BID67.754.8
LCI699 0.5 mg Followed by LCI699 1 mg BID71.058.1
LCI699 1 mg QD73.165.4
Placebo57.654.5

Percentage of Participants With a MSSBP Response and MSSBP Control at Week 8, as Measured by Office Blood Pressure (OBP)

MSSBP response was defined as the percentage of participants with a MSSBP <140 mmHg or a >=20 mmHg reduction from baseline reduction from baseline. MSSBP control was defined as the percentage of participants with a MSSBP <140 mmHg for non-diabetic participants and <130mHg for diabetic participants. (NCT00817635)
Timeframe: Week 8

,,,,
Interventionpercentage of participants (Number)
MSSBP ResponseMSSBP Control
Eplerenone 50 mg BID65.653.1
LCI699 0.25 mg BID54.851.6
LCI699 0.5 mg Followed by LCI699 1 mg BID41.932.3
LCI699 1 mg QD57.750.0
Placebo42.436.4

Change From Baseline in Homeostatic Model Assessment of Insulin Resistance (HOMA-IR)

Insulin resistance was measured using the 75 G glucose tolerance test. Participants ingested 75 grams of glucose in 300-400 mL of water over 5 minutes. Blood samples were taken before ingesting glucose and then every 30 minutes for 120 minutes. HOMA-IR was calculated using the Insulin and glucose levels obtained. A negative change (decrease in insulin resistance) indicates improvement. (NCT01406015)
Timeframe: Baseline and Week 6 (Prior to ingesting glucose and every 30 minutes for 120 minutes)

,
InterventionIR index (Mean)
BaselineChange from Baseline at Week 6
Placebo3.40.1
Spironolactone2.70.1

Change From Baseline in Insulin Sensitivity Index (ISI)

Insulin sensitivity was measured using the 75 gram (G) glucose tolerance test. Participants ingested 75 grams of glucose in 300-400 milliliters (mL) of water over 5 minutes. Blood samples were taken before ingesting glucose and then every 30 minutes for 120 minutes. Insulin sensitivity index was calculated by Matsuda and Defronzo's formula using the values obtained. A positive change from Baseline (increase in insulin sensitivity) indicates improvement. (NCT01406015)
Timeframe: Baseline and Week 6 (Prior to ingesting glucose and every 30 minutes for 120 minutes)

,
InterventionIS index (Mean)
BaselineChange from Baseline at Week 6
Placebo4.6-1.1
Spironolactone3.7-0.1

Change From Baseline in Para-aminohippurate (PAH) Clearance

Renal plasma blood flow was determined by clearance of para-aminohippurate (PAH). A loading dose of PAH (8 mg/kg) was given intravenously followed by a 1 hour constant infusion of PAH at a rate of 12 mg/minute (min). Plasma samples were obtained at Baseline and at 50 and 60 minutes. PAH clearance was calculated from the plasma levels and infusion rates and reported in millimeters (mL)/minute (min). A positive change from Baseline indicates improvement. (NCT01406015)
Timeframe: Baseline and Week 6 (Prior to PAH infusion and at 50 and 60 minutes post PAH infusion)

,
InterventionmL/min (Mean)
BaselineChange from Baseline at Week 6
Placebo521-5.2
Spironolactone488-2.3

Change From Baseline in Post-ischemic Dilatation

Ultrasonography of the brachial artery was performed to evaluate endothelial function by flow mediated dilatation (FMD) studies. A blood pressure cuff was placed on the participant's upper arm and was compressed for 5 minutes. After release of compression, brachial artery diameter and blood flow velocity were measured. FMD was expressed as the percentage change in brachial artery diameter. A positive change from Baseline indicates improvement. (NCT01406015)
Timeframe: Baseline and Week 6

,
Interventionpercent dilalation (Mean)
BaselineChange from Baseline at Week 6
Placebo10.2-2.0
Spironolactone9.6-1.2

Insulin Secretion

Acute Insulin response during Hyperglycemic clamp (delta insulin uU/mL, t=0-10) (NCT00732160)
Timeframe: 3 hours

InterventionuU/mL (Mean)
Vehicle, HS48.9
Vehicle, LS37.6
Aldosterone, HS51.8
Aldosterone, LS34.4

Insulin Sensitivity

Insulin sensitivity index (ISI) was calculated by dividing the average glucose infusion rate (mg glucose infusion/kg body weight/min) by the average insulin concentration (uU/mL) from 90 to 120 minutes. This was multiplied by 100 (thus, x100 in units description), per reporting convention in literature. (NCT00732160)
Timeframe: 3 hours

Interventionmg/kg/min per uU/mL*100 (Mean)
Vehicle, HS25.2
Vehicle, LS24.8
Aldosterone, HS23.4
Aldosterone, LS24.7

Albuminuria

Annual percent change in 24 hour urine albumin, centrally processed. Data from multiple years were analyzed with the primary focus on the change over time for the measure (from the slope of the model). The measure presented is the average annual percent change across the 8 years. (NCT01885559)
Timeframe: up to 8 years (annually assessed)

Interventionannual percent change (Mean)
ACE-I + Placebo7.5
ACE-I + ARB7.3

Aldosterone

Annual percent change in urinary aldosterone, centrally processed measure. Data from multiple years were analyzed with the primary focus on the change over time for the measure (from the slope for time from the model). The measure presented is the average annual percent change across the 8 years. (NCT01885559)
Timeframe: up at 8 years (annually assessed)

Interventionannual percent change (Mean)
ACE-I + Placebo-8.8
ACE-I + ARB-10.2

Back or Flank Pain

Report of back or flank pain since the last visit (yes or no) (NCT01885559)
Timeframe: 48 months

Interventionpercentage of participants at 48 months (Number)
ACE-I + Placebo43
ACE-I + ARB46

Cardiovascular Hospitalizations

Cause-specific hospitalizations (cardiovascular) (NCT01885559)
Timeframe: up to 8 years

Interventionevents (Number)
ACE-I + Placebo29
ACE-I + ARB16

Hospitalizations

Hospitalization for any cause (NCT01885559)
Timeframe: up to 8 years

Interventionevents (Number)
ACE-I + Placebo173
ACE-I + ARB136

Number of Participants With 50% Reduction of Baseline eGFR, End Stage Renal Disease (ESRD, Initiation of Dialysis or Preemptive Transplant), or Death.

(NCT01885559)
Timeframe: Patients followed for 5-8 years with average of 6.5 years follow up

Interventionparticipants (Number)
ACE-I + Placebo116
ACE-I + ARB115

Quality of Life Mental Component Summary

Short Form-36 Quality of Life Mental Component Summary ranges from 0 (worst possible outcome) to 100 (best possible outcome). Data from multiple years were analyzed with the primary focus on the change over time for the measure (from the slope for time from the model). The measure presented is the average annual change across the 8 years. (NCT01885559)
Timeframe: up to 8 years (annually assessed)

Interventionunits on a scale per year (Mean)
ACE-I + Placebo-0.031
ACE-I + ARB-0.079

Quality of Life Physical Component Summary

Short Form-36 Quality of Life Physical Component Summary ranges from 0 (worst possible outcome) to 100 (best possible outcome). Data from multiple years were analyzed with the primary focus on the change over time for the measure (from the slope for time from the model). The measure presented is the average annual change across the 8 years. (NCT01885559)
Timeframe: up to 8 years (annually assessed)

Interventionunits on a scale per year (Mean)
ACE-I + Placebo-0.64
ACE-I + ARB-0.68

Baseline 24-hour Average Systolic Blood Pressure (SBP)

Baseline 24-hour average SBP was assessed using 24-hour ambulatory blood pressure monitoring (ABPM). (NCT01096667)
Timeframe: 24 hours

InterventionmmHg (Mean)
Placebo136.11
Ertugliflozin 1 mg133.13
Ertugliflozin 5 mg135.08
Ertugliflozin 25 mg135.59
HCTZ 12.5mg139.55

Baseline 24-hour Average Urinary Glucose Excretion

Urinary glucose excetion was corrected for a duration of 24 hours (with appropriate duration of collection defined as >20 hours and <28 hours). (NCT01096667)
Timeframe: 24 hours

Interventiongrams/day (Mean)
Placebo13.35
Ertugliflozin 1 mg9.97
Ertugliflozin 5 mg8.04
Ertugliflozin 25 mg17.56
HCTZ 12.5mg6.96

Baseline Fasting Plasma Glucose (FPG)

For FPG, blood was drawn after an overnight fast of at least 8 hours (except water). (NCT01096667)
Timeframe: Baseline

Interventionmg/dL (Mean)
Placebo169.47
Ertugliflozin 1 mg158.38
Ertugliflozin 5 mg158.29
Ertugliflozin 25 mg172.03
HCTZ 12.5mg156.87

Baseline Seated, Triplicate Trough DBP

Trough DBP was measured using an automated blood pressure device with the participant in a seated position for at least 5 minutes before and while the blood pressure measure is obtained. Three measurements of blood pressure were taken at least 2-minutes apart. Baseline trough DBP is calculated as the mean of triplicate (3) trough DBP measures. (NCT01096667)
Timeframe: Baseline

InterventionmmHg (Mean)
Placebo84.89
Ertugliflozin 1 mg83.08
Ertugliflozin 5 mg83.79
Ertugliflozin 25 mg83.89
HCTZ 12.5mg84.72

Baseline Seated, Triplicate Trough Heart Rate

Trough heart rate was measured using an automated blood pressure device with the participant in a seated position for at least 5 minutes before and while the heart rate measure was obtained. Three measurements of heart rate were taken at least 2-minutes apart. Baseline trough heart rate is calculated as the mean of triplicate (3) trough heart rate measures. (NCT01096667)
Timeframe: Baseline

Interventionbeats per minute (Mean)
Placebo77.07
Ertugliflozin 1 mg78.73
Ertugliflozin 5 mg77.30
Ertugliflozin 25 mg75.63
HCTZ 12.5mg77.97

Baseline Seated, Triplicate Trough SBP

Trough SBP was measured using an automated blood pressure device with the participant in a seated position for at least 5 minutes before and while the blood pressure measure is obtained. Three measurements of blood pressure were taken at least 2-minutes apart. Baseline trough SBP is calculated as the mean of triplicate (3) trough SBP measures. (NCT01096667)
Timeframe: Baseline

InterventionmmHg (Mean)
Placebo135.17
Ertugliflozin 1 mg134.23
Ertugliflozin 5 mg137.31
Ertugliflozin 25 mg135.25
HCTZ 12.5mg138.07

Change From Baseline in FPG at Week 2

For FPG, blood was drawn after an overnight fast of at least 8 hours (except water). (NCT01096667)
Timeframe: Baseline and Week 2

Interventionmg/dL (Least Squares Mean)
Placebo-5.44
Ertugliflozin 1 mg-10.98
Ertugliflozin 5 mg-22.45
Ertugliflozin 25 mg-32.03
HCTZ 12.5mg3.21

Change From Baseline in FPG at Week 4

For FPG, blood was drawn after an overnight fast of at least 8 hours (except water). (NCT01096667)
Timeframe: Baseline and Week 4

Interventionmg/dL (Least Squares Mean)
Placebo4.39
Ertugliflozin 1 mg-13.70
Ertugliflozin 5 mg-30.41
Ertugliflozin 25 mg-31.03
HCTZ 12.5mg3.79

Change From Baseline in Seated, Triplicate Trough DBP at Week 4

Trough DBP was measured using an automated blood pressure device with the participant in a seated position for at least 5 minutes before and while the blood pressure measure is obtained. Three measurements of blood pressure were taken at least 2-minutes apart. The change from baseline at Week 4 is the difference between the baseline and Week 4 assessments. (NCT01096667)
Timeframe: Baseline and Week 4

InterventionmmHg (Least Squares Mean)
Placebo0.30
Ertugliflozin 1 mg-0.90
Ertugliflozin 5 mg-0.75
Ertugliflozin 25 mg-2.71
HCTZ 12.5mg-2.54

Change From Baseline in Seated, Triplicate Trough Heart Rate at Week 4

Trough heart rate was measured using an automated blood pressure device with the participant in a seated position for at least 5 minutes before and while the heart rate measure was obtained. Three measurements of heart rate were taken at least 2-minutes apart. The change from baseline at Week 4 is the difference between the baseline and Week 4 assessments. (NCT01096667)
Timeframe: Baseline and Week 4

Interventionbeats per minute (Least Squares Mean)
Placebo2.34
Ertugliflozin 1 mg-1.86
Ertugliflozin 5 mg1.22
Ertugliflozin 25 mg-1.51
HCTZ 12.5mg-0.99

Change From Baseline in Seated, Triplicate Trough SBP at Week 4

Trough SBP was measured using an automated blood pressure device with the participant in a seated position for at least 5 minutes before and while the blood pressure measure is obtained. Three measurements of blood pressure were taken at least 2-minutes apart. The change from baseline at Week 4 is the difference between the baseline and Week 4 assessments. (NCT01096667)
Timeframe: Baseline and Week 4

InterventionmmHg (Least Squares Mean)
Placebo1.24
Ertugliflozin 1 mg-2.77
Ertugliflozin 5 mg-5.92
Ertugliflozin 25 mg-4.96
HCTZ 12.5mg-3.13

Change From Baseline on 24-hour Average DBP at Week 4

Change from baseline on 24-hour average DBP at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. (NCT01096667)
Timeframe: Baseline and Week 4

InterventionmmHg (Least Squares Mean)
Placebo0.77
Ertugliflozin 1 mg-1.89
Ertugliflozin 5 mg-2.34
Ertugliflozin 25 mg-1.50
HCTZ 12.5mg-1.42

Change From Baseline on 24-hour Average Heart Rate at Week 4

Change from baseline in 24-hour average heart rate at Week 4 using 24 hour ABPM. (NCT01096667)
Timeframe: Baseline and Week 4

InterventionBeats per minute (Least Squares Mean)
Placebo1.00
Ertugliflozin 1 mg-1.22
Ertugliflozin 5 mg1.07
Ertugliflozin 25 mg-1.39
HCTZ 12.5mg-0.56

Change From Baseline on 24-hour Average SBP at Week 4

Change from baseline on 24-hour average SBP at Week 4 assessed using 24-hour ABPM. In the case of missing data, last observation carried forward (LOCF). (NCT01096667)
Timeframe: Baseline and Week 4

InterventionmmHg (Least Squares Mean)
Placebo0.26
Ertugliflozin 1 mg-2.71
Ertugliflozin 5 mg-3.73
Ertugliflozin 25 mg-3.42
HCTZ 12.5mg-2.95

Change From Baseline on 24-hour Urinary Glucose Excretion at Week 4

Urinary glucose excetion was corrected for a duration of 24 hours (with appropriate duration of collection defined as >20 hours and <28 hours). In the case of missing data, LOCF. (NCT01096667)
Timeframe: Baseline and Week 4

Interventiongrams/day (Least Squares Mean)
Placebo4.15
Ertugliflozin 1 mg46.33
Ertugliflozin 5 mg64.54
Ertugliflozin 25 mg74.49
HCTZ 12.5mg-0.48

Change From Baseline on Daytime Average DBP at Week 4

Change from baseline on daytime average DBP at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. Daytime was defined as 0600 to 2159 hours, inclusive, local time. (NCT01096667)
Timeframe: Baseline and Week 4

InterventionmmHg (Least Squares Mean)
Placebo0.87
Ertugliflozin 1 mg-2.12
Ertugliflozin 5 mg-1.88
Ertugliflozin 25 mg-1.77
HCTZ 12.5mg-1.69

Change From Baseline on Daytime Average Heart Rate at Week 4

Change from baseline in daytime average heart rate at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. Daytime was defined as 0600 to 2159 hours, inclusive, local time. (NCT01096667)
Timeframe: Baseline and Week 4

InterventionBeats per minute (Least Squares Mean)
Placebo1.58
Ertugliflozin 1 mg-1.80
Ertugliflozin 5 mg1.10
Ertugliflozin 25 mg-1.07
HCTZ 12.5mg-0.06

Change From Baseline on Daytime Average SBP at Week 4

Change from baseline on daytime average SBP at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. Daytime was defined as 0600 to 2159 hours, inclusive, local time. (NCT01096667)
Timeframe: Baseline and Week 4

InterventionmmHg (Least Squares Mean)
Placebo0.82
Ertugliflozin 1 mg-2.88
Ertugliflozin 5 mg-3.61
Ertugliflozin 25 mg-4.17
HCTZ 12.5mg-3.10

Change From Baseline on Nighttime Average DBP at Week 4

Change from baseline on nighttime average DBP at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. Nighttime was defined as 2200 to 0559 hours, inclusive, local time. (NCT01096667)
Timeframe: Baseline and Week 4

InterventionmmHg (Least Squares Mean)
Placebo1.02
Ertugliflozin 1 mg-1.48
Ertugliflozin 5 mg-2.52
Ertugliflozin 25 mg-0.84
HCTZ 12.5mg-0.55

Change From Baseline on Nighttime Average Heart Rate at Week 4

Change from baseline in 24-hour nighttime average heart rate at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. Nighttime was defined as 2200 to 0559 hours, inclusive, local time. (NCT01096667)
Timeframe: Baseline and Week 4

InterventionBeats per minute (Least Squares Mean)
Placebo-0.18
Ertugliflozin 1 mg-0.15
Ertugliflozin 5 mg1.43
Ertugliflozin 25 mg-1.99
HCTZ 12.5mg-1.24

Change From Baseline on Nighttime Average SBP at Week 4

Change from baseline on nighttime average SBP at Week 4 using 24 hour ABPM. In the case of missing data, LOCF. Nighttime was defined as 2200 to 0559 hours, inclusive, local time. (NCT01096667)
Timeframe: Baseline and Week 4

InterventionmmHg (Least Squares Mean)
Placebo-0.29
Ertugliflozin 1 mg-2.48
Ertugliflozin 5 mg-3.47
Ertugliflozin 25 mg-2.31
HCTZ 12.5mg-2.30

Number of Participants Who Discontinued Study Drug Due to an AE

An adverse event is defined as any untoward medical occurrence in a clinical investigation participant administered a product or medical device; the event need not necessarily have a causal relationship with the treatment or usage. The table below includes all data collected since first dose of study drug. Discontinuation of study drug due to an AE includes temporary and permanent discontinuation of study drug due to an AE. (NCT01096667)
Timeframe: Up to 28 days (treatment period)

InterventionParticipants (Number)
Placebo0
Ertugliflozin 1 mg0
Ertugliflozin 5 mg0
Ertugliflozin 25 mg1
HCTZ 12.5mg0

Number of Participants Who Experienced an Adverse Event (AE)

An adverse event is defined as any untoward medical occurrence in a clinical investigation participant administered a product or medical device; the event need not necessarily have a causal relationship with the treatment or usage. The table below includes all data collected since first dose of study drug. (NCT01096667)
Timeframe: Up to 63 days (including run-in, treatment period, and follow-up)

InterventionParticipants (Number)
Placebo9
Ertugliflozin 1 mg8
Ertugliflozin 5 mg15
Ertugliflozin 25 mg12
HCTZ 12.5mg10

Baseline 24-hour, Daytime and Nightime Average Diastolic Blood Pressure (DBP)

Baseline 24-hour average DBP was assessed using 24-hour ABPM. Daytime was defined as 0600 to 2159 hours, inclusive, local time. Nighttime was defined as 2200 to 0559 hours, inclusive, local time. (NCT01096667)
Timeframe: up to 24 hours

,,,,
InterventionmmHg (Mean)
24-hrDaytimeNighttime
Ertugliflozin 1 mg78.6781.7772.05
Ertugliflozin 25 mg80.3683.5973.28
Ertugliflozin 5 mg80.1883.4773.05
HCTZ 12.5mg82.6685.8775.76
Placebo81.8985.3274.24

Baseline 24-hour, Daytime and Nightime Average Heart Rate

Baseline 24-hour average heart rate was assessed using 24-hour ABPM. Daytime was defined as 0600 to 2159 hours, inclusive, local time. Nighttime was defined as 2200 to 0559 hours, inclusive, local time. (NCT01096667)
Timeframe: up to 24 hours

,,,,
Interventionbeats per minute (Mean)
24-hrDaytimeNighttime
Ertugliflozin 1 mg80.7483.7474.44
Ertugliflozin 25 mg79.4182.1873.49
Ertugliflozin 5 mg79.6882.7173.16
HCTZ 12.5mg79.0881.9573.03
Placebo81.1184.4374.05

Baseline Average Daytime and Nighttime SBP

Daytime was defined as 0600 to 2159 hours, inclusive, local time. Nighttime was defined as 2200 to 0559 hours, inclusive, local time. (NCT01096667)
Timeframe: Daytime: 16 hours; Nighttime: 8 hours

,,,,
InterventionmmHg (Mean)
DaytimeNighttime
Ertugliflozin 1 mg136.85125.15
Ertugliflozin 25 mg139.56127.13
Ertugliflozin 5 mg138.89126.37
HCTZ 12.5mg143.32131.68
Placebo139.95127.54

24-h, Wake and Sleep Period Systolic and Diastolic Blood Pressure

"24-h Systolic Blood Pressure is the average of all 24-h Ambulatory Systolic Blood Pressure recordings. The Wake Period Systolic Blood Pressure is the average of all Systolic Blood Pressures recorded every 15 minutes during the wake period. The Sleep Period Systolic Blood pressure is the average of all Systolic Blood Pressures recorded every 30 minutes during the sleep period.~24-h Diastolic Blood Pressure is the average of all 24-h Ambulatory Diastolic Blood Pressure recordings. The Wake Period Diastolic Blood Pressure is the average of all Diastolic Blood Pressures recorded every 15 minutes during the wake period. The Sleep Period Diastolic Blood pressure is the average of all Diastolic Blood Pressures recorded every 30 minutes during the sleep period." (NCT02710071)
Timeframe: At the end of 2 weeks of placebo therapy, at the end of 6 weeks of Nebivolol therapy and at the end of 6 weeks of hydrochlorothiazide therapy.

,,
InterventionmmHg (Mean)
24-h systolic blood pressure24-h diastolic blood pressureWake systolic blood pressureWake diastolic blood pressureSleep systolic blood pressureSleep diastolic blood pressure
Hydrochlorothiazide133801388512775
Nebivolol130771358112371
Placebo137821418612976

Brachial Artery Flow Mediated Dilation

Brachial Artery Flow Mediated Dilation is upper arm brachial artery dilation during the 3 minutes forearm reactive hyperemia following the release of the 5-minute forearm cuff occlusion. (NCT02699125)
Timeframe: At the end of 2 weeks of placebo therapy, at the end of 6 weeks of guanfacine therapy and at the end of 6 weeks of hydrochlorothiazide therapy.

Interventionpercentage of the preoclussion diameter (Mean)
Placebo4.5
Guanfacine8.4
Hydrochlorothiazide4.9

24-h, Wake and Sleep Period Systolic and Diastolic Blood Pressure

"The primary outcome measure is ambulatory systolic and diastolic blood pressure recorded once every 15 minutes during the day and once every 30 minutes during the sleep. The Outcome Measure Data Table present primary outcome as 24-h, Wake and Sleep Period Systolic and Diastolic Blood Pressure after each of the following three interventions: Placebo, Guanfacine and Hydrochlorothiazide." (NCT02699125)
Timeframe: At the end of 2 weeks of placebo therapy, at the end of 6 weeks of guanfacine therapy and at the end of 6 weeks of hydrochlorothiazide therapy.

,,
InterventionmmHg (Mean)
24-h systolic blood pressure24-h diastolic blood pressureWake systolic blood pressureWake diastolic blood pressureSleep systolic blood pressureSleep diastolic blood pressure
Guanfacine133811378412473
Hydrochlorothyazide136831398613076
Placebo143871479113680

Change in Left Ventricular Mass Index (LVMI) From Baseline to End of Study (Week 36)

Left ventricular mass index (LVMI) was measured by magnetic resonance imaging (MRI). An increase in LVMI indicates hypertrophy of the left ventricle. This could be a normal reversible response to cardiovascular conditioning (athletic heart) or an abnormal irreversible response to chronically increased volume load (preload) or increased pressure load (afterload). Thickening of the ventricular muscle results in increased left ventricular pressure, increased end-systolic volume, and decreased end-diastolic volume, causing an overall reduction in cardiac output. (NCT00219141)
Timeframe: Baseline to end of study (Week 36)

Interventiong/m^2 (Least Squares Mean)
Aliskiren 300 mg-5.51
Losartan 100 mg-4.81
Aliskiren/Losartan 300/100 mg-5.61

Change in the Left Ventricular Hypertrophy (LVH) Parameter Cornell Voltage Duration Product as Measured by Electrocardiogram From Baseline to End of Study (Week 36)

(NCT00219141)
Timeframe: Baseline to end of study (Week 36)

Interventionmm * ms (Mean)
Aliskiren 300 mg-104.97
Losartan 100 mg-150.31
Aliskiren/Losartan 300/100 mg-130.65

Change in the Left Ventricular Hypertrophy (LVH) Parameter Diameter of Ascending Aorta as Measured by MRI From Baseline to End of Study (Week 36)

(NCT00219141)
Timeframe: Baseline to end of study (Week 36)

Interventionmm (Mean)
Aliskiren 300 mg-0.71
Losartan 100 mg-0.64
Aliskiren/Losartan 300/100 mg-0.86

Change in the Left Ventricular Hypertrophy (LVH) Parameter Left Ventricular Anteroseptal Wall Thickness as Measured by MRI From Baseline to End of Study (Week 36)

(NCT00219141)
Timeframe: Baseline to end of study (Week 36)

Interventionmm (Mean)
Aliskiren 300 mg-0.95
Losartan 100 mg-1.20
Aliskiren/Losartan 300/100 mg-1.17

Change in the Left Ventricular Hypertrophy (LVH) Parameter Left Ventricular Ejection Fraction as Measured by MRI From Baseline to End of Study (Week 36)

(NCT00219141)
Timeframe: Baseline to end of study (Week 36)

Interventionpercent (Mean)
Aliskiren 300 mg0.62
Losartan 100 mg2.02
Aliskiren/Losartan 300/100 mg1.92

Change in the Left Ventricular Hypertrophy (LVH) Parameter Left Ventricular End Diastolic Mass as Measured by MRI From Baseline to End of Study (Week 36)

(NCT00219141)
Timeframe: Baseline to end of study (Week 36)

Interventiong (Mean)
Aliskiren 300 mg-9.81
Losartan 100 mg-9.92
Aliskiren/Losartan 300/100 mg-12.29

Change in the Left Ventricular Hypertrophy (LVH) Parameter Left Ventricular End Diastolic Volume as Measured by MRI From Baseline to End of Study (Week 36)

(NCT00219141)
Timeframe: Baseline to end of study (Week 36)

InterventionmL (Mean)
Aliskiren 300 mg-7.05
Losartan 100 mg-4.52
Aliskiren/Losartan 300/100 mg-7.03

Change in the Left Ventricular Hypertrophy (LVH) Parameter Left Ventricular End Systolic Volume as Measured by MRI From Baseline to End of Study (Week 36)

(NCT00219141)
Timeframe: Baseline to end of study (Week 36)

InterventionmL (Mean)
Aliskiren 300 mg-3.20
Losartan 100 mg-4.73
Aliskiren/Losartan 300/100 mg-5.14

Change in the Left Ventricular Hypertrophy (LVH) Parameter Left Ventricular Inferolateral Wall Thickness as Measured by MRI From Baseline to End of Study (Week 36)

(NCT00219141)
Timeframe: Baseline to end of study (Week 36)

Interventionmm (Mean)
Aliskiren 300 mg-0.88
Losartan 100 mg-0.89
Aliskiren/Losartan 300/100 mg-0.90

Change in the Left Ventricular Hypertrophy (LVH) Parameter Left Ventricular Mass Index as Measured by MRI From Baseline to End of Study (Week 36)

(NCT00219141)
Timeframe: Baseline to end of study (Week 36)

Interventiong/m^2 (Mean)
Aliskiren 300 mg-4.87
Losartan 100 mg-4.79
Aliskiren/Losartan 300/100 mg-5.81

Change in the Left Ventricular Hypertrophy (LVH) Parameter Left Ventricular Stroke Volume as Measured by MRI From Baseline to End of Study (Week 36)

(NCT00219141)
Timeframe: Baseline to end of study (Week 36)

InterventionmL (Mean)
Aliskiren 300 mg-3.89
Losartan 100 mg0.24
Aliskiren/Losartan 300/100 mg-2.24

Change in the Left Ventricular Hypertrophy (LVH) Parameter Sokolow-Lyon Voltage as Measured by Electrocardiogram From Baseline to End of Study (Week 36)

(NCT00219141)
Timeframe: Baseline to end of study (Week 36)

Interventionmm (Mean)
Aliskiren 300 mg-1.07
Losartan 100 mg-0.97
Aliskiren/Losartan 300/100 mg-1.43

Change From Baseline in Mean 24-hour Ambulatory Diastolic and Systolic Blood Pressure From Baseline to the End of the Study (Week 36)

Two 24-hour ambulatory blood pressure monitoring (ABPM) evaluations were performed, one at baseline and one at the end of the study. For each evaluation, the ABPM device was attached to the non-dominant arm of the patient. A correlation was made between the ABPM device readings and measurements taken with a mercury sphygmomanometer and stethoscope. Following the correlation procedure, blood pressure was measured at study specified intervals. (NCT00219141)
Timeframe: Baseline the end of study (Week 36)

,,
Interventionmm Hg (Least Squares Mean)
SystolicDiastolic
Aliskiren 300 mg-2.67-1.31
Aliskiren/Losartan 300/100 mg-6.97-4.11
Losartan 100 mg-3.81-1.92

Adverse Effects

(NCT01062763)
Timeframe: 4 months

Interventionparticipants (Number)
Addition of Spironolactone4
Placebo0

Change of Diastolic Blood Pressure

Change of diastolic blood pressure from baseline to study end at four months. (NCT01062763)
Timeframe: 4 months

Interventionmm Hg (Mean)
Addition of Spironolactone-3.9
Placebo-0.3

Change of of Systolic Blood Pressure

Change of systolic blood pressure from baseline to study end at four months. (NCT01062763)
Timeframe: 4 months

Interventionmm Hg (Mean)
Addition of Spironolactone-9.6
Placebo-0.7

Blood Pressure During Angiotensin II Infusion

(NCT01502787)
Timeframe: 12 weeks after initiation of metoprolol

InterventionmmHg (Mean)
Metoprolol114
Nebivolol113

Blood Pressure During Exercise

(NCT01502787)
Timeframe: 12 weeks

InterventionmmHg (Mean)
Initial Treatment With Metoprolol101
Initial Treatment With Nebivolol103

Forearm Blood Flow

(NCT01502787)
Timeframe: 12 weeks after each specified medication

Interventionml/min (Mean)
First Intervention Metoprolol: 12 Weeks96
Second Intervention Nebivolol: 24 Weeks105

24 Hour Urinary Catecholamine (DOPA) Excretion During Treatment Normalized to Creatinine

Urine was collected over 24 hours during treatment. The urinary volume was measured and the urine was analyzed for creatinine and catecholamines. Total amounts of creatinine and catecholamines were calculated and the results are expressed as catecholamine:creatinine. (NCT00685919)
Timeframe: Immediately before the 1st dose of Placebo or Carbidopa and ending immediately before the last dose (approximately 24 hours)

InterventionMicrograms per milligrams (ug/mg) (Mean)
Healthy Participants Who Received Placebo as Treatment A or Treatment B0.024
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B0.283
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B0.026
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B0.385

24 Hour Urinary Catecholamine (Dopamine) Excretion During Treatment Normalized to Creatinine

Urine was collected over 24 hours during treatment. The urinary volume was measured and the urine was analyzed for creatinine and catecholamines. Total amounts of creatinine and catecholamines were calculated and the results are expressed as catecholamine:creatinine. (NCT00685919)
Timeframe: Immediately before the 1st dose of Placebo or Carbidopa and ending immediately before the last dose (approximately 24 hours)

InterventionMicrograms per milligrams (ug/mg) (Mean)
Healthy Participants Who Received Placebo as Treatment A or Treatment B0.208
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B0.035
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B0.24
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B0.038

24 Hour Urinary Sodium Excretion During Treatment Normalized to Creatinine

Urine was collected for 24hr during treatment. Urinary volume was measured and the urine was analyzed for sodium and creatinine concentrations. Total amounts of sodium and creatinine excreted over the 24 hr were calculated and results expressed as ratio of sodium:creatinine. (NCT00685919)
Timeframe: Immediately before the 1st dose of placebo or carbidopa to immediately before the 5th dose (approximately 24 hours)

InterventionMilliequivalents per gram (mEq/g) (Mean)
Healthy Participants Who Received Placebo as Treatment A or Treatment B140
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B132
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B137
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B154

Plasma Catecholamines (DOPA) After the Last Dose of Placebo or Carbidopa

Blood samples were collected while resting supine for at least 30 minutes and 2 to 4 hours after lunch. For catecholamine measurements, blood was collected in chilled vacuum tubes with EDTA. Plasma was separated and stored with added reduced glutathione (Amersham International PLC) at -70°C until the assay. Plasma catecholamines were measured by a method that involves batch alumina extraction followed by high-performance liquid chromatography (HPLC) for separation with electrochemical detection and quantification. (NCT00685919)
Timeframe: 8 hours after the last dose of placebo or carbidopa

InterventionPicograms per milliliter (pg/mL) (Mean)
Healthy Participants Who Received Placebo as Treatment A or Treatment B1813
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B20297
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B2104
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B25680

Plasma Catecholamines (Norepinephrine) After the Last Dose of Placebo or Carbidopa

Blood samples were collected while resting supine for at least 30 minutes and 2 to 4 hours after lunch. For catecholamine measurements, blood was collected in chilled vacuum tubes with EDTA. Plasma was separated and stored with added reduced glutathione (Amersham International PLC) at -70°C until the assay. Plasma catecholamines were measured by a method that involves batch alumina extraction followed by high-performance liquid chromatography (HPLC) for separation with electrochemical detection and quantification. (NCT00685919)
Timeframe: 8 hours after the last dose of placebo or carbidopa

InterventionPicograms per milliliter (pg/mL) (Mean)
Healthy Participants Who Received Placebo as Treatment A or Treatment B150
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B181
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B278
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B245

Plasma Sodium After the Last Dose of Placebo or Carbidopa

Blood samples were collected while resting supine for at least 30 minutes and 2 to 4 hours after lunch. Samples were processed and sent to the Vanderbilt Clinical Laboratory for assay. (NCT00685919)
Timeframe: 8 hours after the last dose of placebo or carbidopa

InterventionMilliequivalents per liter (mEq/L) (Mean)
Healthy Participants Who Received Placebo as Treatment A or Treatment B138
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B138
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B139
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B138

Supine Plasma Renin Activity 2 Hours After the Last Dose of Placebo or Carbidopa

Blood samples were collected while resting supine for at least 30 minutes and 1 1/2 to 2 hours after breakfast. Samples were processed and sent to the Vanderbilt Clinic Laboratory for assay. (NCT00685919)
Timeframe: 2 hours after the last dose of placebo or carbidopa

InterventionNanograms per milliliter per hour (ng/mL (Mean)
Healthy Participants Who Received Placebo as Treatment A or Treatment B1.153
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B1.033
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B1.544
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B1.878

Systolic Blood Pressure Measured at 8 Hours After the Last Dose of Placebo or Carbidopa

Systolic blood pressure was measured once using a Dinamap non-invasive oscillometric blood pressure monitor, 2-4 hours after lunch and after at least 30 minutes of resting supine. (NCT00685919)
Timeframe: 8 hours after the last dose of placebo or carbidopa

Interventionmillimeters of mercury (mmHg) (Mean)
Healthy Participants Who Received Placebo as Treatment A or Treatment B103
Healthy Participants Who Received Carbidopa as Treatment A or Treatment B101
Postural Tachycardia Syndrome (POTS) Participants Who Received Placebo as Treatment A or Treatment B102
Postural Tachycardia Syndrome (POTS) Patients Who Received Carbidopa as Treatment A or Treatment B101

Blood Pressure

(NCT00627861)
Timeframe: all visits (weekly for 12 weeks)

Interventionmm Hg (Number)
Week 1-SystolicWeek 1-DiastolicWeek 2-SystolicWeek 2-DiastolicWeek 3-SystolicWeek 3-DiastolicWeek 4-SystolicWeek 4-DiastolicWeek 5-SystolicWeek 5-DiastolicWeek 6-SystolicWeek 6-DiastolicWeek 7-SystolicWeek 7-DiastolicWeek 8-SystolicWeek 8-DiastolicWeek 9-SystolicWeek 9 -DiastolicWeek 10-SystolicWeek 10-DiastolicWeek 11-SystolicWeek 11-DiastolicWeek 12-SystolicWeek 12-Diastolic
Aliskiren and Metoprolol146641448814890148921569215084157891477612994139791709014678

Plasma Renin Activity

The blood test, plasma renin activity or PRA, is being measured during the visits outlined. (NCT00627861)
Timeframe: screening, 4th, 6th, 7th, 9th, 10th, 11th, 12th weeks

Interventionng/mL/h (Number)
ScreeningWeek 4Week 6Week 7Week 9Week 10Week 11Week 12
Aliskiren and Metoprolol2.071.220.280.180.280.070.030.06

Plasma Renin Concentration

(NCT00627861)
Timeframe: 5th, 6th, 7th, 9th, 10th, 11th, 12th weeks

Interventionpg/mL (Number)
Week 5Week 6Week 7Week 9Week 10Week 11Week 12
Aliskiren and Metoprolol16.513.520.5222.74.43.2

Reviews

799 reviews available for aldosterone and Hypertension

ArticleYear
Adrenal venous sampling in the diagnostic workup of primary aldosteronism.
    The British journal of radiology, 2022, Jan-01, Volume: 95, Issue:1129

    Topics: Adrenal Glands; Aldosterone; Blood Specimen Collection; Humans; Hyperaldosteronism; Hypertension; Ma

2022
Diagnosis and treatment of primary aldosteronism.
    The lancet. Diabetes & endocrinology, 2021, Volume: 9, Issue:12

    Topics: Adenoma; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertensio

2021
Effect of diuretics on plasma aldosterone and potassium in primary hypertension: A systematic review and meta-analysis.
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:5

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Diuretics; Humans; Hypertension; Potassium; Th

2022
[Conn's syndrome-Frequent and still too rarely diagnosed to underdiagnosed].
    Der Internist, 2022, Volume: 63, Issue:1

    Topics: Adrenalectomy; Aldosterone; Diabetes Mellitus, Type 2; Humans; Hyperaldosteronism; Hypertension; Ren

2022
Mechanical dependency of the SARS-CoV-2 virus and the renin-angiotensin-aldosterone (RAAS) axis: a possible new threat.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:41

    Topics: Aldosterone; Angiotensins; COVID-19; Humans; Hypertension; Peptidyl-Dipeptidase A; Renin; Renin-Angi

2022
Primary Aldosteronism, Aldosterone, and Extracellular Vesicles.
    Endocrinology, 2022, 01-01, Volume: 163, Issue:1

    Topics: Aldosterone; Biomarkers; Extracellular Vesicles; Gene Expression Regulation; Humans; Hyperaldosteron

2022
[Diagnosis of primary hyperaldosteronism].
    Medicina clinica, 2022, 05-13, Volume: 158, Issue:9

    Topics: Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

2022
Prognosis of adrenalectomy guided by computed tomography versus adrenal vein sampling in patients with primary aldosteronism: A systematic review and meta-analysis.
    Journal of clinical hypertension (Greenwich, Conn.), 2022, Volume: 24, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Prognosis; Ret

2022
Primary Aldosteronism: Where Are We Now? Where to From Here?
    Hypertension (Dallas, Tex. : 1979), 2022, Volume: 79, Issue:4

    Topics: Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Sodium, Dietary

2022
The Role of Aldosterone in OSA and OSA-Related Hypertension.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Aldosterone; Continuous Positive Airway Pressure; Humans; Hyperaldosteronism; Hypertension; Sleep Ap

2021
High Prevalence of Autonomous Aldosterone Production in Hypertension: How to Identify and Treat It.
    Current hypertension reports, 2022, Volume: 24, Issue:5

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Prevalence; Renin

2022
Chronic hypertension and superimposed preeclampsia: screening and diagnosis.
    American journal of obstetrics and gynecology, 2022, Volume: 226, Issue:2S

    Topics: Aldosterone; Angiogenic Proteins; Biomarkers; Chronic Disease; Cytokines; Female; Humans; Hypertensi

2022
Mosaic theory revised: inflammation and salt play central roles in arterial hypertension.
    Cellular & molecular immunology, 2022, Volume: 19, Issue:5

    Topics: Aldosterone; Humans; Hypertension; Inflammation; Sodium Chloride, Dietary

2022
Hyperaldosteronism: How Current Concepts Are Transforming the Diagnostic and Therapeutic Paradigm.
    Kidney360, 2020, 10-29, Volume: 1, Issue:10

    Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

2020
Aldosterone and cardiovascular diseases.
    Cardiovascular research, 2023, 03-17, Volume: 119, Issue:1

    Topics: Aldosterone; Atherosclerosis; Atrial Fibrillation; Cardiovascular Diseases; Heart Failure; Humans; H

2023
Aldosterone breakthrough from a pharmacological perspective.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2022, Volume: 45, Issue:6

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypertension

2022
11-Deoxycorticosterone Producing Adrenal Hyperplasia as a Very Unusual Cause of Endocrine Hypertension: Case Report and Systematic Review of the Literature.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Carcinoma; Desoxycorti

2022
Diagnostic value of aldosterone to renin ratio calculated by plasma renin activity or plasma renin concentration in primary aldosteronism: a meta-analysis.
    Chinese medical journal, 2022, Mar-20, Volume: 135, Issue:6

    Topics: Aldosterone; Area Under Curve; Humans; Hyperaldosteronism; Hypertension; Renin

2022
Primary Aldosteronism and Resistant Hypertension: A Pathophysiological Insight.
    International journal of molecular sciences, 2022, Apr-27, Volume: 23, Issue:9

    Topics: Aldosterone; Fibrosis; Humans; Hyperaldosteronism; Hypertension; Kidney

2022
Performance of the aldosterone-to-renin ratio as a screening test for primary aldosteronism in primary care.
    Endocrine, 2022, Volume: 77, Issue:1

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Primary Health Care; Renin

2022
Renin-Angiotensin Aldosterone System Inhibitors and COVID-19: A Systematic Review and Meta-Analysis Revealing Critical Bias Across a Body of Observational Research.
    Journal of the American Heart Association, 2022, 06-07, Volume: 11, Issue:11

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonis

2022
Management and Outcomes of Primary Aldosteronism in Pregnancy: A Systematic Review.
    Hypertension (Dallas, Tex. : 1979), 2022, Volume: 79, Issue:9

    Topics: Adrenalectomy; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Pregnancy; Retrospecti

2022
Renin-Angiotensin-Aldosterone Inhibitors and COVID-19 Infection.
    Current hypertension reports, 2022, Volume: 24, Issue:10

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angi

2022
Pathogenesis of Primary Aldosteronism: Impact on Clinical Outcome.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenocortical Adenoma; Aldosterone; Cytochrome P-450 CYP11B2; G Protein-Coupled Inwardly-Rectifying

2022
Update on the Genetics of Primary Aldosteronism and Aldosterone-Producing Adenomas.
    Current cardiology reports, 2022, Volume: 24, Issue:9

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Aldosterone; G P

2022
Focus on adrenal and related causes of hypertension in childhood and adolescence: Rare or rarely recognized?
    Archives of endocrinology and metabolism, 2022, Nov-17, Volume: 66, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Child; Humans; Hydrocortisone; Hypertension

2022
Salt Sensitivity of Blood Pressure in Women.
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:2

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Receptors, Mineralo

2023
Primary aldosteronism - a multidimensional syndrome.
    Nature reviews. Endocrinology, 2022, Volume: 18, Issue:11

    Topics: Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Risk Factors; Syndrome

2022
Influence and implications of the renin-angiotensin-aldosterone system in obstructive sleep apnea: An updated systematic review and meta-analysis.
    Journal of sleep research, 2023, Volume: 32, Issue:1

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Hormones; Humans; Hypertension; Renin; Renin-Angiotensi

2023
Salt, Not Always a Cardiovascular Enemy? A Mini-Review and Modern Perspective.
    Medicina (Kaunas, Lithuania), 2022, Aug-29, Volume: 58, Issue:9

    Topics: Aldosterone; Blood Pressure; Endothelin-1; Humans; Hypertension; Nitric Oxide; Receptors, Mineraloco

2022
Promise of Physiological Profiling to Prevent Stroke in People of African Ancestry: Prototyping Ghana.
    Current neurology and neuroscience reports, 2022, Volume: 22, Issue:11

    Topics: Aldosterone; Antihypertensive Agents; Ghana; Humans; Hypertension; Multicenter Studies as Topic; Ren

2022
Role of α1-blockers in the current management of hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2022, Volume: 24, Issue:9

    Topics: Adrenergic alpha-Antagonists; Aged; Aldosterone; Antihypertensive Agents; Diuretics; Doxazosin; Huma

2022
Who should be screened for primary aldosteronism? A comprehensive review of current evidence.
    Journal of clinical hypertension (Greenwich, Conn.), 2022, Volume: 24, Issue:9

    Topics: Adrenal Gland Neoplasms; Aldosterone; Diuretics; Humans; Hyperaldosteronism; Hypertension; Renin

2022
Blood pressure effects of sodium transport along the distal nephron.
    Kidney international, 2022, Volume: 102, Issue:6

    Topics: Aldosterone; Animals; Blood Pressure; Humans; Hypertension; Mammals; Nephrons; Sodium

2022
Primary aldosteronism and obstructive sleep apnea: What do we know thus far?
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Sleep Apnea, Obstructive

2022
Personalized Treatment of Patients With Primary Aldosteronism.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2023, Volume: 29, Issue:6

    Topics: Aldosterone; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Patient-Cente

2023
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors

2022
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors

2022
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors

2022
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors

2022
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors

2022
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors

2022
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors

2022
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors

2022
Neutrophil gelatinase-associated lipocalin as an immunomodulator in endocrine hypertension.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Fibrosis; Humans; Hypertension; Immunologic Factors

2022
Vascular and hormonal interactions in the adrenal gland.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldoster

2022
Vascular and hormonal interactions in the adrenal gland.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldoster

2022
Vascular and hormonal interactions in the adrenal gland.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldoster

2022
Vascular and hormonal interactions in the adrenal gland.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldoster

2022
CASZ1: a promising factor modulating aldosterone biosynthesis and mineralocorticoid receptor activity.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:2

    Topics: Aldosterone; Chromatography, Liquid; DNA-Binding Proteins; Genome-Wide Association Study; Humans; Hy

2023
CASZ1: a promising factor modulating aldosterone biosynthesis and mineralocorticoid receptor activity.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:2

    Topics: Aldosterone; Chromatography, Liquid; DNA-Binding Proteins; Genome-Wide Association Study; Humans; Hy

2023
CASZ1: a promising factor modulating aldosterone biosynthesis and mineralocorticoid receptor activity.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:2

    Topics: Aldosterone; Chromatography, Liquid; DNA-Binding Proteins; Genome-Wide Association Study; Humans; Hy

2023
CASZ1: a promising factor modulating aldosterone biosynthesis and mineralocorticoid receptor activity.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:2

    Topics: Aldosterone; Chromatography, Liquid; DNA-Binding Proteins; Genome-Wide Association Study; Humans; Hy

2023
[The genetic background of primary aldosteronism].
    Orvosi hetilap, 2023, Mar-05, Volume: 164, Issue:9

    Topics: Adrenocortical Adenoma; Aldosterone; Genetic Background; Humans; Hyperaldosteronism; Hypertension

2023
Cardiovascular and metabolic characters of
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Adenoma; Adrenocortical Adenoma; Aldosterone; Female; G Protein-Coupled Inwardly-Rectifying Potassiu

2023
Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:5

    Topics: Aldosterone; American Heart Association; Cardiovascular Diseases; Female; Humans; Hypertension; Moth

2023
Underdiagnosis of Primary Aldosteronism: A Review of Screening and Detection.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2023, Volume: 82, Issue:3

    Topics: Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Renin

2023
The Effect of Aldosterone on Cardiorenal and Metabolic Systems.
    International journal of molecular sciences, 2023, Mar-11, Volume: 24, Issue:6

    Topics: Aldosterone; Cardiovascular Diseases; Essential Hypertension; Humans; Hyperaldosteronism; Hypertensi

2023
Primary Aldosteronism Prevalence - An Unfolding Story.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2023, Volume: 131, Issue:7-08

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Prevalence; Renin

2023
Prognostic models to predict complete resolution of hypertension after adrenalectomy in primary aldosteronism: A systematic review and meta-analysis.
    Clinical endocrinology, 2023, Volume: 99, Issue:1

    Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Progno

2023
Improving Detection Rates for Primary Aldosteronism.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2023, Volume: 131, Issue:7-08

    Topics: Aldosterone; Blood Pressure; Heart Disease Risk Factors; Humans; Hyperaldosteronism; Hypertension; P

2023
Recent progress in the diagnosis and treatment of primary aldosteronism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:7

    Topics: Aldosterone; Glucose; Humans; Hyperaldosteronism; Hyperkalemia; Hypertension; Mineralocorticoid Rece

2023
Ca
    Handbook of experimental pharmacology, 2023, Volume: 279

    Topics: Aldosterone; Calcium Channels, T-Type; Calcium Signaling; Humans; Hyperaldosteronism; Hypertension;

2023
Advances in the molecular imaging of primary aldosteronism.
    Annals of nuclear medicine, 2023, Volume: 37, Issue:8

    Topics: Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Molecular Imaging; Tomography

2023
Mineralocorticoid receptor signalling in primary aldosteronism.
    The Journal of endocrinology, 2023, 09-01, Volume: 259, Issue:1

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Quali

2023
Role of NCC in the pathophysiology of hypertension in primary aldosteronism.
    Current opinion in nephrology and hypertension, 2023, 09-01, Volume: 32, Issue:5

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Kidney Tubules, Distal; Phosp

2023
G protein-coupled estrogen receptor: a promising therapeutic target for aldosterone-induced hypertension.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Aldosterone; Estrogens; Female; GTP-Binding Proteins; Humans; Hypertension; Receptors, Estrogen; Rec

2023
Key to the Treatment of Primary Aldosteronism in Secondary Hypertension: Subtype Diagnosis.
    Current hypertension reports, 2023, Volume: 25, Issue:12

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertensi

2023
Primary aldosteronism 2.0: an update for clinicians on diagnosis and treatment.
    Polish archives of internal medicine, 2023, 10-26, Volume: 133, Issue:10

    Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension

2023
Therapeutic management of congenital forms of endocrine hypertension.
    European journal of endocrinology, 2023, Nov-08, Volume: 189, Issue:5

    Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocort

2023
A low dietary sodium dose is associated with a more pronounced aldosterone response in normotensive than in hypertensive individuals.
    Scientific reports, 2023, 11-03, Volume: 13, Issue:1

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Randomized Controlled Trials as Topic; Sodium; So

2023
Antifibrotic Roles of RAAS Blockers: Update.
    Advances in experimental medicine and biology, 2019, Volume: 1165

    Topics: Aldosterone; Angiotensin I; Blood Pressure; Humans; Hypertension; Mineralocorticoid Receptor Antagon

2019
Steroid Profiling and Immunohistochemistry for Subtyping and Outcome Prediction in Primary Aldosteronism-a Review.
    Current hypertension reports, 2019, 09-03, Volume: 21, Issue:10

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Chromatography, Liquid; Cytochrome P-

2019
Mineralocorticoid Receptor and Endothelial Dysfunction in Hypertension.
    Current hypertension reports, 2019, 09-04, Volume: 21, Issue:10

    Topics: Aldosterone; Animals; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Epithelial S

2019
Monogenic hypertension.
    Acta bio-medica : Atenei Parmensis, 2019, 09-30, Volume: 90, Issue:10-S

    Topics: Aldosterone; Genetic Testing; High-Throughput Nucleotide Sequencing; Humans; Hydrocortisone; Hyperte

2019
Low-Renin Hypertension.
    Endocrinology and metabolism clinics of North America, 2019, Volume: 48, Issue:4

    Topics: Aldosterone; Citrus paradisi; Cushing Syndrome; Glycyrrhiza; Humans; Hyperaldosteronism; Hypertensio

2019
Resistant Hypertension: A Clinical Perspective.
    Endocrinology and metabolism clinics of North America, 2019, Volume: 48, Issue:4

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Liddle Syndrome; Renin

2019
[Secondary hypertension in women].
    Presse medicale (Paris, France : 1983), 2019, Volume: 48, Issue:11 Pt 1

    Topics: Adult; Age Factors; Aldosterone; Computed Tomography Angiography; Female; Fibromuscular Dysplasia; H

2019
Arterial Hypertension, Aldosterone, and Atrial Fibrillation.
    Current hypertension reports, 2019, 11-18, Volume: 21, Issue:12

    Topics: Aldosterone; Atrial Fibrillation; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Randomize

2019
[Hormonal Assessment of Secondary Hypertension - How to do it and what to expect?]
    Presse medicale (Paris, France : 1983), 2019, Volume: 48, Issue:12

    Topics: Aldosterone; Antihypertensive Agents; Blood Chemical Analysis; Diagnosis, Differential; Diagnostic T

2019
Primary Aldosteronism: JACC State-of-the-Art Review.
    Journal of the American College of Cardiology, 2019, 12-03, Volume: 74, Issue:22

    Topics: Adrenal Glands; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension

2019
Primary aldosteronism: Treatment of the disease, and new therapeutic approaches.
    Best practice & research. Clinical endocrinology & metabolism, 2020, Volume: 34, Issue:2

    Topics: Adrenalectomy; Aldosterone; Antihypertensive Agents; Endocrinology; Humans; Hyperaldosteronism; Hype

2020
Associations between primary aldosteronism and diabetes, poor bone health, and sleep apnea-what do we know so far?
    Journal of human hypertension, 2020, Volume: 34, Issue:1

    Topics: Aldosterone; Bone Density; Diabetes Mellitus; Disease Management; Humans; Hyperaldosteronism; Hypert

2020
Prevalence, diagnosis and outcomes of treatment for primary aldosteronism.
    Best practice & research. Clinical endocrinology & metabolism, 2020, Volume: 34, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenocortical Adenoma; Aldosterone; Diagnostic Techniques, Endocrine; Huma

2020
The importance of the epithelial sodium channel in determining salt sensitivity in people of African origin.
    Pediatric nephrology (Berlin, Germany), 2021, Volume: 36, Issue:2

    Topics: Aldosterone; Amiloride; Blood Pressure; Epithelial Sodium Channels; Humans; Hypertension; Sodium; So

2021
Sodium pumps, ouabain and aldosterone in the brain: A neuromodulatory pathway underlying salt-sensitive hypertension and heart failure.
    Cell calcium, 2020, Volume: 86

    Topics: Aldosterone; Animals; Brain; Heart Failure; Humans; Hypertension; Ouabain; Sodium Chloride, Dietary;

2020
Old and new genes in primary aldosteronism.
    Best practice & research. Clinical endocrinology & metabolism, 2020, Volume: 34, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Genetic Association Studies; Genetic

2020
Recent insights into sodium and potassium handling by the aldosterone-sensitive distal nephron: implications on pathophysiology and drug discovery.
    Journal of nephrology, 2020, Volume: 33, Issue:3

    Topics: Aldosterone; Drug Discovery; Humans; Hypertension; Nephrons; Potassium; Sodium

2020
The spectrum of low-renin hypertension.
    Best practice & research. Clinical endocrinology & metabolism, 2020, Volume: 34, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Molecular Diagnostic Techniques; Renin

2020
MicroRNAs and Adrenocortical Tumors: Where do we Stand on Primary Aldosteronism?
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2020, Volume: 52, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertens

2020
Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2020, Volume: 52, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II Type 1 Receptor Blocke

2020
The cardiovascular consequences of hyperaldosteronism.
    Annales d'endocrinologie, 2021, Volume: 82, Issue:3-4

    Topics: Aldosterone; Blood Pressure; Cardiovascular Diseases; Humans; Hyperaldosteronism; Hypertension

2021
The Potential Role of Aldosterone-Producing Cell Clusters in Adrenal Disease.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2020, Volume: 52, Issue:6

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Cytoc

2020
Salt Appetite and its Effects on Cardiovascular Risk in Primary Aldosteronism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2020, Volume: 52, Issue:6

    Topics: Aldosterone; Appetite; Cardiovascular Diseases; Feeding Behavior; Heart Disease Risk Factors; Humans

2020
Hypokalemia and the Prevalence of Primary Aldosteronism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2020, Volume: 52, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Disease Progression; Humans; Hyperald

2020
Primary aldosteronism is a public health issue: challenges and opportunities.
    Journal of human hypertension, 2020, Volume: 34, Issue:7

    Topics: Aldosterone; Blood Pressure; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension; Publi

2020
Renin-angiotensin-aldosterone system and COVID-19 infection.
    Annales d'endocrinologie, 2020, Volume: 81, Issue:2-3

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-C

2020
Oxidative Stress: A Unifying Paradigm in Hypertension.
    The Canadian journal of cardiology, 2020, Volume: 36, Issue:5

    Topics: Aldosterone; Angiotensin II; Endothelin-1; Endothelium, Vascular; Humans; Hypertension; Inflammation

2020
Aldosterone receptor antagonists.
    Annales d'endocrinologie, 2021, Volume: 82, Issue:3-4

    Topics: Aldosterone; Blood Pressure; Heart Failure; Humans; Hypertension; Mineralocorticoid Receptor Antagon

2021
[Update and Research Progress in the Diagnosis of Primary Aldosteronism].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2020, Volume: 51, Issue:3

    Topics: Aldosterone; Captopril; Humans; Hyperaldosteronism; Hypertension; Renin

2020
Genetic and Genomic Mechanisms of Primary Aldosteronism.
    Trends in molecular medicine, 2020, Volume: 26, Issue:9

    Topics: Adrenocortical Adenoma; Aldosterone; Animals; Calcium Signaling; Genetics; Genomics; Humans; Hyperal

2020
Treatment of primary hyperaldosteronism.
    Medicina clinica, 2020, 10-09, Volume: 155, Issue:7

    Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Ant

2020
Pathogenesis and treatment of primary aldosteronism.
    Nature reviews. Endocrinology, 2020, Volume: 16, Issue:10

    Topics: Adrenal Glands; Aldosterone; Animals; Humans; Hyperaldosteronism; Hypertension; Mutation

2020
Aldosterone, Inflammation, Immune System, and Hypertension.
    American journal of hypertension, 2021, 02-18, Volume: 34, Issue:1

    Topics: Aldosterone; Blood Pressure; Cardiometabolic Risk Factors; Humans; Hypertension; Immunity; Water-Ele

2021
Evolution of the Primary Aldosteronism Syndrome: Updating the Approach.
    The Journal of clinical endocrinology and metabolism, 2020, 12-01, Volume: 105, Issue:12

    Topics: Aldosterone; Blood Pressure; Diagnostic Techniques, Endocrine; Humans; Hyperaldosteronism; Hypertens

2020
Five Reasons for the Failure to Diagnose Aldosterone Excess in Hypertension.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2020, Volume: 52, Issue:12

    Topics: Aldosterone; Diagnosis, Differential; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension

2020
Left ventricular remodeling and dysfunction in primary aldosteronism.
    Journal of human hypertension, 2021, Volume: 35, Issue:2

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypertrophy, Left Ventricular; Ventricular Dy

2021
Female Sex, a Major Risk Factor for Salt-Sensitive Hypertension.
    Current hypertension reports, 2020, 10-21, Volume: 22, Issue:12

    Topics: Aldosterone; Female; Humans; Hypertension; Male; Receptors, Mineralocorticoid; Risk Factors; Sodium

2020
Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride.
    The Cochrane database of systematic reviews, 2020, 12-12, Volume: 12

    Topics: Aldosterone; Asian People; Bias; Black People; Blood Pressure; Catecholamines; Cholesterol; Confiden

2020
Confounders of the aldosterone-to-renin ratio when used as a screening test in hypertensive patients: A critical analysis of the literature.
    Journal of clinical hypertension (Greenwich, Conn.), 2021, Volume: 23, Issue:2

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Renin-Angiotensin System

2021
The Mineralocorticoid Receptor in Salt-Sensitive Hypertension and Renal Injury.
    Journal of the American Society of Nephrology : JASN, 2021, Volume: 32, Issue:2

    Topics: Acute Kidney Injury; Aldosterone; Humans; Hypertension; Metabolic Syndrome; Receptors, Mineralocorti

2021
The effect of medication on the aldosterone-to-renin ratio. A critical review of the literature.
    Journal of clinical hypertension (Greenwich, Conn.), 2021, Volume: 23, Issue:2

    Topics: Aldosterone; Antihypertensive Agents; Humans; Hyperaldosteronism; Hypertension; Renin

2021
China nationwide screening and registry of primary aldosteronism in hypertensive patients.
    Journal of human hypertension, 2021, Volume: 35, Issue:2

    Topics: Aldosterone; China; Humans; Hyperaldosteronism; Hypertension; Multicenter Studies as Topic; Prospect

2021
Aldosterone sensitivity: an opportunity to explore the pathogenesis of hypertension.
    American journal of physiology. Renal physiology, 2021, 03-01, Volume: 320, Issue:3

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Drug Resistance; Humans; Hypertension

2021
The mineralocorticoid receptor-an emerging player in metabolic syndrome?
    Journal of human hypertension, 2021, Volume: 35, Issue:2

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Metabolic Syndrome; Mineralocorticoid Recepto

2021
New Genetic Polymorphisms as an Epidemiological Factor of Arterial Hypertension in Patients with Hyposodical Diet.
    Current hypertension reviews, 2022, Volume: 18, Issue:1

    Topics: Aldosterone; Diet; Humans; Hypertension; Polymorphism, Genetic; Renin; Renin-Angiotensin System; Sod

2022
[Hyperaldosteronism].
    Der Internist, 2021, Volume: 62, Issue:3

    Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Minera

2021
Kidney and epigenetic mechanisms of salt-sensitive hypertension.
    Nature reviews. Nephrology, 2021, Volume: 17, Issue:5

    Topics: Aging; Aldosterone; Angiotensin II; Animals; DNA Methylation; Fetal Nutrition Disorders; Glucuronida

2021
How common is primary aldosteronism?
    Current opinion in nephrology and hypertension, 2021, 05-01, Volume: 30, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

2021
Functional Characteristic and Significance of Aldosterone-Producing Cell Clusters in Primary Aldosteronism and Age-Related Hypertension.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Age Factors; Aging; Aldosterone; H

2021
Primary aldosteronism.
    Trends in cardiovascular medicine, 2022, Volume: 32, Issue:4

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Prevalence; Renin

2022
Pathophysiology of Hypertension: The Mosaic Theory and Beyond.
    Circulation research, 2021, 04-02, Volume: 128, Issue:7

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Blood Vessels; Body Fluids; Central Nervous System; Hum

2021
Unravelling the Genetic Basis of Primary Aldosteronism.
    Nutrients, 2021, Mar-08, Volume: 13, Issue:3

    Topics: Aldosterone; Germ-Line Mutation; High-Throughput Nucleotide Sequencing; Humans; Hyperaldosteronism;

2021
DNA Methylation of the Angiotensinogen Gene,
    International journal of molecular sciences, 2021, Apr-27, Volume: 22, Issue:9

    Topics: Aldosterone; Angiotensin II; Angiotensinogen; Cardiovascular Diseases; CCAAT-Enhancer-Binding Protei

2021
A systematic review of nonsynonymous single nucleotide polymorphisms in the renin-angiotensin-aldosterone system.
    Cardiology journal, 2022, Volume: 29, Issue:6

    Topics: Aldosterone; Humans; Hypertension; Polymorphism, Single Nucleotide; Renin; Renin-Angiotensin System

2022
Sexual Dimorphism of Corticosteroid Signaling during Kidney Development.
    International journal of molecular sciences, 2021, May-18, Volume: 22, Issue:10

    Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Blood Pressure; Gene Expression Regulation, Developme

2021
Therapeutic Outcomes with Surgical and Medical Management of Primary Aldosteronism.
    Current cardiology reports, 2021, 06-03, Volume: 23, Issue:7

    Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Ant

2021
Chronic use of renin-angiotensin-aldosterone inhibitors in hypertensive COVID-19 patients: Results from a Spanish registry and meta-analysis.
    Medicina clinica, 2022, 04-08, Volume: 158, Issue:7

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensins; Antihypertensive Agents; COVID-19; Huma

2022
Primary Aldosteronism: a Continuum from Normotension to Hypertension.
    Current cardiology reports, 2021, 07-01, Volume: 23, Issue:8

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Kidney; Renin

2021
Sex steroids receptors, hypertension, and vascular ageing.
    Journal of human hypertension, 2022, Volume: 36, Issue:2

    Topics: Adolescent; Aging; Aldosterone; Female; Humans; Hypertension; Male; Receptors, Steroid; Renin-Angiot

2022
Primary Aldosteronism Presenting with Hypertension Five Days after Delivery: A Case Report and Literature Review.
    Internal medicine (Tokyo, Japan), 2022, Feb-15, Volume: 61, Issue:4

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Female; Humans;

2022
Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride.
    The Cochrane database of systematic reviews, 2017, 04-09, Volume: 4

    Topics: Aldosterone; Asian People; Black People; Blood Pressure; Catecholamines; Cholesterol; Diet, Sodium-R

2017
Mineralocorticoid Receptor Blockade in End-Stage Renal Disease.
    Current hypertension reports, 2017, Volume: 19, Issue:5

    Topics: Aldosterone; Humans; Hypertension; Kidney Failure, Chronic; Mineralocorticoid Receptor Antagonists;

2017
Primary aldosteronism: a common cause of resistant hypertension.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2017, 06-05, Volume: 189, Issue:22

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

2017
The association between consistent licorice ingestion, hypertension and hypokalaemia: a systematic review and meta-analysis.
    Journal of human hypertension, 2017, Volume: 31, Issue:11

    Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Female; Glycyrrhiza; Glycyrrhizic Acid; Humans; Hype

2017
Adrenal venous sampling for primary aldosteronism: laboratory medicine best practice.
    Journal of clinical pathology, 2017, Volume: 70, Issue:11

    Topics: Adrenal Cortex Function Tests; Adrenal Glands; Aldosterone; Biomarkers; Blood Specimen Collection; H

2017
Endothelial factors in the pathogenesis and treatment of chronic kidney disease Part I: General mechanisms: a joint consensus statement from the European Society of Hypertension Working Group on Endothelin and Endothelial Factors and The Japanese Society
    Journal of hypertension, 2018, Volume: 36, Issue:3

    Topics: Aldosterone; Animals; Arterial Pressure; Consensus; Endothelin-1; Endothelium, Vascular; Fibrosis; G

2018
Primary Aldosteronism and Obstructive Sleep Apnea: Is This A Bidirectional Relationship?
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2017, Volume: 49, Issue:12

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Prevalence; Risk Factors; Sle

2017
Aging and Adrenal Aldosterone Production.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:2

    Topics: Adrenal Cortex; Aging; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mutation

2018
Overview of aldosterone-related genetic syndromes and recent advances.
    Current opinion in endocrinology, diabetes, and obesity, 2018, Volume: 25, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Age Factors; Aging; Aldosterone; C

2018
Primary aldosteronism in the primary care setting.
    Current opinion in endocrinology, diabetes, and obesity, 2018, Volume: 25, Issue:3

    Topics: Adrenalectomy; Aldosterone; Blood Pressure; Cardiovascular Diseases; Cerebrovascular Disorders; Huma

2018
Hypertension in Blacks: Individualized Therapy Based on Renin/Aldosterone Phenotyping.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 72, Issue:2

    Topics: Aldosterone; Antihypertensive Agents; Black People; Blood Pressure; Global Health; Humans; Hypertens

2018
Role of Renin-Angiotensin-Aldosterone System Activation in Promoting Cardiovascular Fibrosis and Stiffness.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 72, Issue:3

    Topics: Aldosterone; Cardiovascular Diseases; Cardiovascular System; Fibrosis; Humans; Hypertension; Models,

2018
Primary Aldosteronism: Practical Approach to Diagnosis and Management.
    Circulation, 2018, 08-21, Volume: 138, Issue:8

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hyperal

2018
Leptin and Aldosterone.
    Vitamins and hormones, 2019, Volume: 109

    Topics: Aldosterone; Animals; Female; Gene Expression Regulation; Humans; Hypertension; Leptin; Male; Obesit

2019
The renin-angiotensin-aldosterone system and its suppression.
    Journal of veterinary internal medicine, 2019, Volume: 33, Issue:2

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit

2019
Eplerenone Versus Spironolactone in Resistant Hypertension: an Efficacy and/or Cost or Just a Men's Issue?
    Current hypertension reports, 2019, 03-02, Volume: 21, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Eplerenone; Humans; Hypertension; Mineralocorticoid Receptor A

2019
Treatment of Resistant and Refractory Hypertension.
    Circulation research, 2019, 03-29, Volume: 124, Issue:7

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Drug Resistance; Drug Therapy, Combin

2019
Role of Pendrin in the Pathophysiology of Aldosterone-Induced Hypertension.
    American journal of hypertension, 2019, 06-11, Volume: 32, Issue:7

    Topics: Acid-Base Equilibrium; Aldosterone; Animals; Blood Pressure; Humans; Hyperaldosteronism; Hypertensio

2019
The aldosterone to renin ratio in the diagnosis of primary aldosteronism: Promises and challenges.
    International journal of clinical practice, 2019, Volume: 73, Issue:7

    Topics: Aldosterone; Biomarkers; Humans; Hyperaldosteronism; Hypertension; Practice Guidelines as Topic; Ren

2019
Obesity, kidney dysfunction and hypertension: mechanistic links.
    Nature reviews. Nephrology, 2019, Volume: 15, Issue:6

    Topics: Adipokines; Aldosterone; Angiotensin II; Humans; Hypertension; Kidney; Kidney Tubules; Leptin; Obesi

2019
K
    The Journal of physiology, 2019, Volume: 597, Issue:17

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Potassium; Reni

2019
[Update in the clinical management of low renin hypertension].
    Revista medica de Chile, 2019, Volume: 147, Issue:4

    Topics: Aldosterone; Disease Management; Humans; Hypertension; Receptors, Mineralocorticoid; Renin; Renin-An

2019
Effectiveness of Thermal Ablation for Aldosterone-Producing Adrenal Adenoma: A Systematic Review and Meta-Analysis of Clinical and Biochemical Parameters.
    Journal of vascular and interventional radiology : JVIR, 2019, Volume: 30, Issue:9

    Topics: Ablation Techniques; Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Antihypertensive Agents;

2019
ENaC modulators and renal disease.
    Current molecular pharmacology, 2013, Volume: 6, Issue:1

    Topics: Aldosterone; Diuretics; Epithelial Sodium Channel Agonists; Epithelial Sodium Channel Blockers; Epit

2013
Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials.
    BMJ (Clinical research ed.), 2013, Apr-03, Volume: 346

    Topics: Aldosterone; Biomarkers; Blood Pressure; Cardiovascular Diseases; Diet, Sodium-Restricted; Female; H

2013
Pathophysiology of genetic deficiency in tissue kallikrein activity in mouse and man.
    Thrombosis and haemostasis, 2013, Volume: 110, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Diabetes Mellitus; Humans; Hypertension; Ischemia; Kidney; Kin

2013
Immune system alterations by aldosterone during hypertension: from clinical observations to genomic and non-genomic mechanisms leading to vascular damage.
    Current molecular medicine, 2013, Volume: 13, Issue:6

    Topics: Aldosterone; Blood Vessels; Genome, Human; Humans; Hypertension; Immune System; Oxidative Stress

2013
Genetics of mineralocorticoid excess: an update for clinicians.
    European journal of endocrinology, 2013, Volume: 169, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Animals; Disease Models, Animal; G Pr

2013
Effect of longer-term modest salt reduction on blood pressure.
    The Cochrane database of systematic reviews, 2013, Apr-30, Issue:4

    Topics: Age Factors; Aldosterone; Blood Pressure; Humans; Hypertension; Lipids; Norepinephrine; Randomized C

2013
Smooth muscle cell mineralocorticoid receptors: role in vascular function and contribution to cardiovascular disease.
    Pflugers Archiv : European journal of physiology, 2013, Volume: 465, Issue:12

    Topics: Aging; Aldosterone; Angiotensin II; Animals; Atherosclerosis; Blood Pressure; Cardiovascular Disease

2013
Inhibition of the renin-angiotensin-aldosterone system for cerebrorenal protection.
    Contributions to nephrology, 2013, Volume: 179

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyperte

2013
Aldosterone mediates cardiac fibrosis in the setting of hypertension.
    Current hypertension reports, 2013, Volume: 15, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Cytochrome P-450 CYP11B2; Fibrosis; Heart Diseases; Humans; Hy

2013
A critical review of the evidence supporting aldosterone in the etiology and its blockade in the treatment of obesity-associated hypertension.
    Journal of human hypertension, 2014, Volume: 28, Issue:1

    Topics: Aldosterone; Evidence-Based Medicine; Humans; Hypertension; Mineralocorticoid Receptor Antagonists;

2014
Diagnosis and management of primary aldosteronism: an updated review.
    Annals of medicine, 2013, Volume: 45, Issue:4

    Topics: Adenoma; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenalectomy; Aldosterone; Humans; Hypera

2013
Mineralocorticoid receptors in vascular disease: connecting molecular pathways to clinical implications.
    Current atherosclerosis reports, 2013, Volume: 15, Issue:7

    Topics: Aldosterone; Animals; Atherosclerosis; Blood Pressure; Cardiovascular Diseases; Disease Progression;

2013
Regulation of aldosterone biosynthesis by the Kir3.4 (KCNJ5) potassium channel.
    Clinical and experimental pharmacology & physiology, 2013, Volume: 40, Issue:12

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II; Cell Membrane; G Prot

2013
Aldosterone receptor antagonists: current perspectives and therapies.
    Vascular health and risk management, 2013, Volume: 9

    Topics: Aldosterone; Animals; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Rec

2013
Sex differences in angiotensin II- and aldosterone-induced hypertension: the central protective effects of estrogen.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2013, Volume: 305, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Brain; Estrogens; Humans; Hypertension; Models, Biological; Re

2013
Aldosterone synthase inhibition in hypertension.
    Current hypertension reports, 2013, Volume: 15, Issue:5

    Topics: Aldosterone; Animals; Antihypertensive Agents; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Humans;

2013
Endocrine and hypertensive disorders of potassium regulation: primary aldosteronism.
    Seminars in nephrology, 2013, Volume: 33, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Eplerenone; Humans; Hy

2013
Diagnosis and treatment of unilateral forms of primary aldosteronism.
    Current hypertension reviews, 2013, Volume: 9, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hyper

2013
Primary aldosteronism: a new insight into pathogenesis, diagnosis, and treatment in hypertensive patients.
    Polskie Archiwum Medycyny Wewnetrznej, 2013, Volume: 123, Issue:10

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Mineralocorticoid Receptor Antag

2013
Aberrant Rac1-mineralocorticoid receptor pathways in salt-sensitive hypertension.
    Clinical and experimental pharmacology & physiology, 2013, Volume: 40, Issue:12

    Topics: Aldosterone; Animals; Humans; Hypertension; Kidney; Metabolic Syndrome; rac1 GTP-Binding Protein; Ra

2013
Aldosterone and blood pressure regulation: recent milestones on the long and winding road from electrocortin to KCNJ5, GPER, and beyond.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:1

    Topics: Aldosterone; Blood Pressure; Cardiovascular System; G Protein-Coupled Inwardly-Rectifying Potassium

2014
[Presentations and management of adrenal hypertension].
    Presse medicale (Paris, France : 1983), 2014, Volume: 43, Issue:4 Pt 1

    Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone;

2014
Regulation of Potassium Homeostasis.
    Clinical journal of the American Society of Nephrology : CJASN, 2015, Jun-05, Volume: 10, Issue:6

    Topics: Aldosterone; Animals; Circadian Rhythm; Homeostasis; Humans; Hypertension; Kidney; Potassium; Renal

2015
Actions of circulating angiotensin II and aldosterone in the brain contributing to hypertension.
    American journal of hypertension, 2014, Volume: 27, Issue:8

    Topics: Aldosterone; Angiotensin II; Brain Chemistry; Humans; Hypertension; Neurotransmitter Agents; Renin-A

2014
Aldosterone excess and resistant hypertension: investigation and treatment.
    Current hypertension reports, 2014, Volume: 16, Issue:7

    Topics: Aldosterone; Animals; Drug Resistance; Humans; Hypertension; Quality of Life; Renin; Reproducibility

2014
[Renin-aldosterone and bone metabolism].
    Clinical calcium, 2014, Volume: 24, Issue:6

    Topics: Acute Kidney Injury; Aldosterone; Angiotensin II; Animals; Bone and Bones; Calcium; Cardiovascular D

2014
The inextricable role of the kidney in hypertension.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:6

    Topics: Aldosterone; Animals; Blood Pressure; Homeostasis; Humans; Hypertension; Kidney; Models, Biological;

2014
[Organ damage and cardiorenal syndrome in acute heart failure].
    Medicina clinica, 2014, Volume: 142 Suppl 1

    Topics: Aldosterone; Cardiac Output; Cardio-Renal Syndrome; Comorbidity; Endothelium, Vascular; Heart Failur

2014
Expression and gene variation studies deny association of human HSD3B1 gene with aldosterone production or blood pressure.
    American journal of hypertension, 2015, Volume: 28, Issue:1

    Topics: Adrenal Cortex; Aged; Aldosterone; Blood Pressure; Cells, Cultured; Female; Gene Expression Regulati

2015
Resistant hypertension in diabetes mellitus.
    Current diabetes reports, 2014, Volume: 14, Issue:8

    Topics: Aldosterone; Diabetes Mellitus; Humans; Hypertension; Leptin; Obesity; Sympathetic Nervous System

2014
Comparison of agents that affect aldosterone action.
    Seminars in nephrology, 2014, Volume: 34, Issue:3

    Topics: Aldosterone; Animals; Epithelial Sodium Channel Blockers; Humans; Hydrocortisone; Hyperaldosteronism

2014
Aldosterone and volume management in hypertensive heart disease.
    Seminars in nephrology, 2014, Volume: 34, Issue:3

    Topics: Aldosterone; Area Under Curve; Diuretics; Eplerenone; Heart Failure; Humans; Hypertension; Mineraloc

2014
Increased aldosterone: mechanism of hypertension in obesity.
    Seminars in nephrology, 2014, Volume: 34, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Humans; Hypertension; Obesity

2014
Clock genes in hypertension: novel insights from rodent models.
    Blood pressure monitoring, 2014, Volume: 19, Issue:5

    Topics: Aldosterone; Animals; ARNTL Transcription Factors; Blood Vessels; Circadian Rhythm; CLOCK Proteins;

2014
Bidirectional relationship of hypertension with obstructive sleep apnea.
    Current opinion in pulmonary medicine, 2014, Volume: 20, Issue:6

    Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Continuous Positive Airway Pressure; Die

2014
[Primary hyperaldosteronism: boundaries of diagnostics and therapy].
    Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139, Issue:40

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adrenocortical Hyperfunction; Aldos

2014
Effects of T-type calcium channel blockers on renal function and aldosterone in patients with hypertension: a systematic review and meta-analysis.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Adult; Aged; Aldosterone; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Ty

2014
Update in primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:1

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Quality of Life

2015
Mineralocorticoid receptor activation and mineralocorticoid receptor antagonist treatment in cardiac and renal diseases.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Blood Pressure; Clinical Trials as Topi

2015
Mineralocorticoid-induced sodium appetite and renal salt retention: evidence for common signaling and effector mechanisms.
    Nephron. Physiology, 2014, Volume: 128, Issue:1-2

    Topics: Aldosterone; Angiotensin II; Animals; Appetite; Blood Pressure; Epithelial Sodium Channels; Humans;

2014
Pathogenesis of drug-resistant hypertension.
    Seminars in nephrology, 2014, Volume: 34, Issue:5

    Topics: Age Factors; Aldosterone; Blood Pressure; Coronary Vasospasm; Drug Resistance; Humans; Hypertension;

2014
Pathophysiology and treatment of resistant hypertension: the role of aldosterone and amiloride-sensitive sodium channels.
    Seminars in nephrology, 2014, Volume: 34, Issue:5

    Topics: Aldosterone; Amiloride; Antihypertensive Agents; Blood Pressure; Coronary Vasospasm; Diuretics; Drug

2014
The mineralocorticoid receptor: a new player controlling energy homeostasis.
    Hormone molecular biology and clinical investigation, 2013, Volume: 15, Issue:2

    Topics: Adipose Tissue; Aldosterone; Animals; Energy Metabolism; Homeostasis; Humans; Hypertension; Metaboli

2013
Apparent treatment-resistant hypertension and chronic kidney disease: another cardiovascular-renal syndrome?
    Advances in chronic kidney disease, 2014, Volume: 21, Issue:6

    Topics: Aldosterone; Antihypertensive Agents; Blood Volume; Cardio-Renal Syndrome; Coronary Vasospasm; Diure

2014
Dual renin-angiotensin-aldosterone blockade: promises and pitfalls.
    Current hypertension reports, 2015, Volume: 17, Issue:1

    Topics: Aldosterone; Angiotensins; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Mineraloco

2015
Comparison of aldosterone synthesis in adrenal cells, effect of various AT1 receptor blockers with or without atrial natriuretic peptide.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:5

    Topics: Adrenal Glands; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Atrial Natriuretic Factor; Cel

2015
Recent topics on podocytes and aldosterone.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2015, Volume: 25, Issue:2

    Topics: Aldosterone; Animals; Disease Models, Animal; Humans; Hypertension; Metabolic Syndrome; Mice; Podocy

2015
Renal mechanisms of salt-sensitive hypertension: contribution of two steroid receptor-associated pathways.
    American journal of physiology. Renal physiology, 2015, Mar-01, Volume: 308, Issue:5

    Topics: Aldosterone; Animals; Circadian Rhythm; Disease Models, Animal; Epithelial Sodium Channels; Humans;

2015
Transforming growth factor beta1 and aldosterone.
    Current opinion in nephrology and hypertension, 2015, Volume: 24, Issue:2

    Topics: Aldosterone; Animals; Humans; Hypertension; Kidney; Renin-Angiotensin System; Sodium; Transforming G

2015
Laboratory challenges in primary aldosteronism screening and diagnosis.
    Clinical biochemistry, 2015, Volume: 48, Issue:6

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Practice Guidelines as Topic;

2015
[Hypertension in the course of primary aldosteronism during pregnancy].
    Postepy higieny i medycyny doswiadczalnej (Online), 2015, Feb-15, Volume: 69

    Topics: Acid Sensing Ion Channel Blockers; Aldosterone; Amiloride; Antihypertensive Agents; Eplerenone; Fema

2015
Hypertension: renin-angiotensin-aldosterone system alterations.
    Circulation research, 2015, Mar-13, Volume: 116, Issue:6

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim

2015
Obesity-induced hypertension: interaction of neurohumoral and renal mechanisms.
    Circulation research, 2015, Mar-13, Volume: 116, Issue:6

    Topics: Aldosterone; Animals; Antihypertensive Agents; Dyslipidemias; Heart Conduction System; Hemodynamics;

2015
Relative roles of principal and intercalated cells in the regulation of sodium balance and blood pressure.
    Current hypertension reports, 2015, Volume: 17, Issue:4

    Topics: Aldosterone; Animals; Biological Transport; Blood Pressure; Humans; Hypertension; Kidney; Sodium; So

2015
Issues in the Diagnosis and Treatment of Primary Aldosteronism.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2016, Volume: 23, Issue:2

    Topics: Aldosterone; Biomarkers; Critical Pathways; Humans; Hyperaldosteronism; Hypertension; Practice Guide

2016
Mineralocorticoid and apparent mineralocorticoid syndromes of secondary hypertension.
    Advances in chronic kidney disease, 2015, Volume: 22, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocortical Adenoma; Aldosterone; Drug

2015
[Genetic alterations in primary aldosteronism].
    Medecine sciences : M/S, 2015, Volume: 31, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Animals; Calcium Channels, L-Type; G

2015
Atlas of tissue renin-angiotensin-aldosterone system in human: A transcriptomic meta-analysis.
    Scientific reports, 2015, May-20, Volume: 5

    Topics: Aldosterone; Cluster Analysis; Databases, Factual; Gene Expression; Humans; Hypertension; Multigene

2015
Renin and aldosterone measurements in the management of arterial hypertension.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2015, Volume: 47, Issue:6

    Topics: Aldosterone; Humans; Hypertension; Renin

2015
Aldosterone biosynthesis in the human adrenal cortex and associated disorders.
    The Journal of steroid biochemistry and molecular biology, 2015, Volume: 153

    Topics: Adrenal Cortex; Aldosterone; Biosynthetic Pathways; Gene Expression Regulation; Humans; Hyperaldoste

2015
Aldosterone and the Mineralocorticoid Receptor: Risk Factors for Cardiometabolic Disorders.
    Current hypertension reports, 2015, Volume: 17, Issue:7

    Topics: Aldosterone; Cardiovascular Diseases; Humans; Hypertension; Metabolic Syndrome; Obesity; Receptors,

2015
Reviving the use of aldosterone inhibitors in treating hypertension in obesity.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Nov-01, Volume: 309, Issue:9

    Topics: Aldosterone; Animals; Evidence-Based Medicine; Humans; Hypertension; Mineralocorticoid Receptor Anta

2015
Pharmacological treatment of aldosterone excess.
    Pharmacology & therapeutics, 2015, Volume: 154

    Topics: Aldosterone; Cytochrome P-450 CYP11B2; Dihydropyridines; Drug Interactions; Epithelial Sodium Channe

2015
The roles of sensitization and neuroplasticity in the long-term regulation of blood pressure and hypertension.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Dec-01, Volume: 309, Issue:11

    Topics: Adaptation, Physiological; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiovascular Syst

2015
[Primary aldosteronism: new insights into familial forms].
    Nederlands tijdschrift voor geneeskunde, 2015, Volume: 159

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; DNA Mutational Analysis; G Protein-Co

2015
Aldosterone and Left Ventricular Remodeling.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2015, Volume: 47, Issue:13

    Topics: Aldosterone; Essential Hypertension; Heart Ventricles; Humans; Hyperaldosteronism; Hypertension; Ven

2015
Urinary extracellular vesicles as markers to assess kidney sodium transport.
    Current opinion in nephrology and hypertension, 2016, Volume: 25, Issue:2

    Topics: Aldosterone; Animals; Biomarkers; Epithelial Sodium Channels; Extracellular Vesicles; Humans; Hypert

2016
The potential of targeting CYP11B.
    Expert opinion on therapeutic targets, 2016, Volume: 20, Issue:8

    Topics: Aldosterone; Animals; Cardiomegaly; Cytochrome P-450 CYP11B2; Drug Design; Humans; Hypertension; Imi

2016
Resistant Hypertension and the Pivotal Role for Mineralocorticoid Receptor Antagonists: A Clinical Update 2016.
    The American journal of medicine, 2016, Volume: 129, Issue:7

    Topics: Age Factors; Aldosterone; Blood Pressure Monitoring, Ambulatory; Comorbidity; Diabetes Mellitus; Hum

2016
The Role of Aldosterone in Obesity-Related Hypertension.
    American journal of hypertension, 2016, Volume: 29, Issue:4

    Topics: Aldosterone; Animals; Blood Pressure; Caloric Restriction; Diet, Sodium-Restricted; Humans; Hyperald

2016
The Different Therapeutic Choices with ARBs. Which One to Give? When? Why?
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2016, Volume: 16, Issue:4

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressu

2016
Apparent mineralocorticoid excess.
    The Journal of steroid biochemistry and molecular biology, 2017, Volume: 165, Issue:Pt A

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Antihypertensive Agents; Cortisone; Diagno

2017
Hyperaldosteronism: Screening and Diagnostic Tests.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2016, Volume: 23, Issue:2

    Topics: Aldosterone; Biomarkers; Critical Pathways; Humans; Hyperaldosteronism; Hypertension; Mass Screening

2016
Hyperaldosteronism: How to Discriminate Among Different Disease Forms?
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2016, Volume: 23, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Aldosterone; Biomarkers; Diagnos

2016
Potassium: friend or foe?
    Pediatric nephrology (Berlin, Germany), 2017, Volume: 32, Issue:7

    Topics: Aldosterone; Cation Exchange Resins; Cell Membrane; Child; Heart Failure; Homeostasis; Humans; Hyper

2017
Vascular Mineralocorticoid Receptors: Linking Risk Factors, Hypertension, and Heart Disease.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 68, Issue:1

    Topics: Aldosterone; Blood Vessels; Heart Diseases; Humans; Hypertension; Receptors, Mineralocorticoid; Risk

2016
Syndromes that Mimic an Excess of Mineralocorticoids.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2016, Volume: 23, Issue:3

    Topics: Aldosterone; Biomarkers; Cushing Syndrome; Dexamethasone; Diet; Genetic Predisposition to Disease; G

2016
Obesity, hypertension and aldosterone: is leptin the link?
    The Journal of endocrinology, 2016, Volume: 230, Issue:1

    Topics: Adipose Tissue; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Leptin; Male; Obesity

2016
Adipocytes, aldosterone and obesity-related hypertension.
    Journal of molecular endocrinology, 2016, Volume: 57, Issue:1

    Topics: Adipocytes; Adrenal Glands; Aldosterone; Animals; Biomarkers; Energy Metabolism; Gene Expression Reg

2016
Clock genes and salt-sensitive hypertension: a new type of aldosterone-synthesizing enzyme controlled by the circadian clock and angiotensin II.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2016, Volume: 39, Issue:10

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldosterone; Angiotensin II; Animals; Circadian Clocks; Circadian R

2016
Sodium and potassium in the pathogenesis of hypertension: focus on the brain.
    Current opinion in nephrology and hypertension, 2017, Volume: 26, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Brain; Humans; Hypertension; Ouabain; Oxidative Stress; Potass

2017
Vascular Consequences of Aldosterone Excess and Mineralocorticoid Receptor Antagonism.
    Current hypertension reviews, 2017, Volume: 13, Issue:1

    Topics: Aldosterone; Animals; Cardiovascular Diseases; Endothelium, Vascular; Epithelial Cells; Humans; Hype

2017
Radiofrequency ablation treatment for aldosterone-producing adenomas.
    Current opinion in endocrinology, diabetes, and obesity, 2017, Volume: 24, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Catheter Ablation; Hum

2017
ACTH and Polymorphisms at Steroidogenic Loci as Determinants of Aldosterone Secretion and Blood Pressure.
    International journal of molecular sciences, 2017, Mar-07, Volume: 18, Issue:3

    Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure; Cytochrome P-450 CYP11B2; Genetic

2017
Role of the renin-angiotensin system in vascular inflammation.
    Trends in pharmacological sciences, 2008, Volume: 29, Issue:7

    Topics: Aldosterone; Angiotensin II; Animals; Capillary Permeability; Chemokine CCL2; Humans; Hypertension;

2008
The role of aldosterone in cardiovascular disease in people with diabetes and hypertension: an update.
    Current diabetes reports, 2008, Volume: 8, Issue:3

    Topics: Aldosterone; Cardiovascular Diseases; Diabetes Complications; Humans; Hypertension; Insulin Resistan

2008
[System renin-aldosterone in fat tissue and other organ and tissues].
    Vnitrni lekarstvi, 2008, Volume: 54, Issue:5

    Topics: Adipose Tissue; Aldosterone; Humans; Hypertension; Metabolic Syndrome; Obesity; Renin

2008
Molecular and clinical investigations in patients with low-renin hypertension.
    Clinical and experimental nephrology, 2009, Volume: 13, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Diuretics; Down-Regulation; Drug Resistance; D

2009
Mineralocorticoid antagonism and cardiac hypertrophy.
    Current hypertension reports, 2008, Volume: 10, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Cardiomegaly; Fibrosis; Humans; Hyperaldosteronism; Hypertensi

2008
Obesity, sleep apnea, aldosterone, and hypertension.
    Current hypertension reports, 2008, Volume: 10, Issue:3

    Topics: Aldosterone; Humans; Hypertension; Metabolic Syndrome; Mineralocorticoid Receptor Antagonists; Obesi

2008
Circulating endothelial progenitor cells in cardiovascular disorders.
    Expert review of cardiovascular therapy, 2008, Volume: 6, Issue:8

    Topics: Acute Coronary Syndrome; Aldosterone; Animals; Apoptosis; Cardiovascular Diseases; Diabetes Mellitus

2008
Altered corticosteroid biosynthesis in essential hypertension: A digenic phenomenon.
    Molecular and cellular endocrinology, 2009, Mar-05, Volume: 300, Issue:1-2

    Topics: Aldosterone; Blood Pressure; Cytochrome P-450 CYP11B2; Humans; Hypertension; Polymorphism, Genetic;

2009
[Primary aldosteronism].
    Revista medica de Chile, 2008, Volume: 136, Issue:7

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Renin; Renin-Angiotensin Syst

2008
Aldosterone as an independent factor in cerebrovascular damage.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2008, Volume: 30, Issue:8

    Topics: Aldosterone; Animals; Blood Pressure; Cerebrovascular Disorders; Disease Models, Animal; Humans; Hyp

2008
Aldosterone and cardiovascular disease.
    Current problems in cardiology, 2009, Volume: 34, Issue:2

    Topics: Adrenalectomy; Aldosterone; Animals; Antihypertensive Agents; Cardiovascular Agents; Cardiovascular

2009
Reconsidering the roles of the mineralocorticoid receptor.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:2

    Topics: Aldosterone; Blood Pressure; Heart Failure; Humans; Hydrocortisone; Hypertension; Mineralocorticoid

2009
[Kidney and hypertension].
    Nihon Jinzo Gakkai shi, 2009, Volume: 51, Issue:1

    Topics: Aldosterone; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Kidney Tubules; Oxidative Str

2009
[Primary hyperaldosteronisms: from diagnosis to treatment].
    Presse medicale (Paris, France : 1983), 2009, Volume: 38, Issue:4

    Topics: Adrenal Cortex Function Tests; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Antihypertensive

2009
Interaction of aldosterone and extracellular volume in the pathogenesis of obesity-associated kidney disease: a narrative review.
    American journal of nephrology, 2009, Volume: 30, Issue:2

    Topics: Aldosterone; Animals; Diabetes Complications; Humans; Hypertension; Insulin Resistance; Kidney; Kidn

2009
Effects of eplerenone, a selective mineralocorticoid receptor antagonist, on clinical and experimental salt-sensitive hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:5

    Topics: Aldosterone; Animals; Disease Models, Animal; Eplerenone; Humans; Hypertension; Mineralocorticoid Re

2009
Investigating hypertension in a young person.
    BMJ (Clinical research ed.), 2009, Apr-06, Volume: 338

    Topics: Adult; Aldosterone; Humans; Hypertension; Kidney Diseases; Male; Referral and Consultation; Renin; U

2009
Resistant hypertension: who and how to evaluate.
    Current opinion in cardiology, 2009, Volume: 24, Issue:4

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Humans; Hyperaldosteron

2009
Narrative review: the emerging clinical implications of the role of aldosterone in the metabolic syndrome and resistant hypertension.
    Annals of internal medicine, 2009, Jun-02, Volume: 150, Issue:11

    Topics: Aldosterone; Cardiovascular Diseases; Endothelium, Vascular; Humans; Hypertension; Insulin Resistanc

2009
Aldosterone-receptor antagonism in hypertension.
    Journal of hypertension, 2009, Volume: 27, Issue:4

    Topics: Albuminuria; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Arrhythmias, Cardiac; D

2009
Mineralocorticoid receptor activation in obesity hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:8

    Topics: Aldosterone; Animals; Biological Evolution; Humans; Hypertension; Ligands; Metabolic Syndrome; Miner

2009
[Development of hypertension and RAAS].
    Nihon Jinzo Gakkai shi, 2009, Volume: 51, Issue:4

    Topics: Aldosterone; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Humans; Hypertension; Peptid

2009
[The renin-angiotensin system].
    Der Urologe. Ausg. A, 2009, Volume: 48, Issue:8

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2009
The role of 11β-hydroxysteroid dehydrogenase type 2 in human hypertension.
    Biochimica et biophysica acta, 2010, Volume: 1802, Issue:12

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Blood Pressure; Colon; Corticoste

2010
Aldosterone and arterial hypertension.
    Nature reviews. Endocrinology, 2010, Volume: 6, Issue:2

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Blood Vessels; Brain; Cytochrome P-45

2010
Aliskiren: a new inhibitor of renin-angiotensin aldosterone system activity.
    Minerva endocrinologica, 2009, Volume: 34, Issue:4

    Topics: Aldosterone; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibito

2009
Aldosterone, sodium, and hypertension: lessons from torcetrapib?
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:2

    Topics: Aldosterone; Animals; Anticholesteremic Agents; Cholesterol Ester Transfer Proteins; Humans; Hyperch

2010
Aldosterone in uremia - beyond blood pressure.
    Blood purification, 2010, Volume: 29, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Endothelial Cells; Endothelium, Vascular;

2010
Mineralocorticoid receptors, salt-sensitive hypertension, and metabolic syndrome.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:4

    Topics: Aldosterone; Animals; Humans; Hypertension; Metabolic Syndrome; Rats; Rats, Inbred Dahl; Receptors,

2010
The central role of the brain aldosterone-"ouabain" pathway in salt-sensitive hypertension.
    Biochimica et biophysica acta, 2010, Volume: 1802, Issue:12

    Topics: Aldosterone; Angiotensin II; Animals; Choroid Plexus; Ependyma; Epithelial Sodium Channels; Humans;

2010
Aldosterone renin ratio in patients with resistant hypertension.
    QJM : monthly journal of the Association of Physicians, 2010, Volume: 103, Issue:11

    Topics: Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Predictive Value of Tests; Renin

2010
Midkine regulation of the renin-angiotensin system.
    Current hypertension reports, 2010, Volume: 12, Issue:2

    Topics: Acetylcholinesterase; Acute Kidney Injury; Aldosterone; Angiotensin II; Animals; Central Nervous Sys

2010
Hypertension in women: the role of progesterone and aldosterone.
    Climacteric : the journal of the International Menopause Society, 2010, Volume: 13, Issue:4

    Topics: Aged; Aldosterone; Androstenes; Animals; Cardiovascular Diseases; Diet, Sodium-Restricted; Estradiol

2010
Aldosterone: role in edematous disorders, hypertension, chronic renal failure, and metabolic syndrome.
    Clinical journal of the American Society of Nephrology : CJASN, 2010, Volume: 5, Issue:6

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Drug Resistance; Dru

2010
Epithelial Na+ channel (ENaC), hormones, and hypertension.
    The Journal of biological chemistry, 2010, Jul-30, Volume: 285, Issue:31

    Topics: Aldosterone; Animals; Antihypertensive Agents; Epithelial Sodium Channels; Genomics; Hormones; Human

2010
Drug mechanisms to help in managing resistant hypertension in obesity.
    Current hypertension reports, 2010, Volume: 12, Issue:4

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Life Style; Mineralocort

2010
Activation of the aldosterone/mineralocorticoid receptor system in chronic kidney disease and metabolic syndrome.
    Clinical and experimental nephrology, 2010, Volume: 14, Issue:4

    Topics: Aldosterone; Animals; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Humans; Hypertensi

2010
Mineralocorticoid receptor antagonists and the metabolic syndrome.
    Current hypertension reports, 2010, Volume: 12, Issue:4

    Topics: Aldosterone; Antihypertensive Agents; Eplerenone; Humans; Hypertension; Inflammation; Insulin Resist

2010
The epithelial sodium channel and the control of sodium balance.
    Biochimica et biophysica acta, 2010, Volume: 1802, Issue:12

    Topics: Aldosterone; Animals; Blood Pressure; Epithelial Sodium Channels; Humans; Hypertension; Nephrons; Re

2010
Role of epithelial sodium channels and their regulators in hypertension.
    The Journal of biological chemistry, 2010, Oct-01, Volume: 285, Issue:40

    Topics: Aldosterone; Animals; Blood Pressure; Epithelial Sodium Channels; Humans; Hypertension; Mutation; Ne

2010
Aldosterone, hypertension and heart failure: insights from clinical trials.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:9

    Topics: Aldosterone; Animals; Anticholesteremic Agents; Atorvastatin; Clinical Trials as Topic; Dihydrotesto

2010
A systemic review of the relationship between aldosterone synthase - 344 C/T polymorphism and hypertension in Han.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2010, Volume: 32, Issue:5

    Topics: Aldosterone; China; Female; Genetic Predisposition to Disease; Humans; Hypertension; Male; Polymorph

2010
Prevalence and diagnosis of primary aldosteronism.
    Current hypertension reports, 2010, Volume: 12, Issue:5

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Blood Chemical Analysis; Blood Pressure Monitoring, Ambu

2010
Cardiovascular and renal damage in primary aldosteronism: outcomes after treatment.
    American journal of hypertension, 2010, Volume: 23, Issue:12

    Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Cardiovascular System; Humans; Hyperaldosteroni

2010
Roles of bone morphogenetic protein-6 in aldosterone regulation by adrenocortical cells.
    Acta medica Okayama, 2010, Volume: 64, Issue:4

    Topics: Adrenal Cortex; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Bone Morphogenetic Protein 6;

2010
Endogenous ouabain: a link between sodium intake and hypertension.
    Current hypertension reports, 2011, Volume: 13, Issue:1

    Topics: Aldosterone; Diet; Humans; Hypertension; Nutritional Status; Ouabain; Receptors, Cell Surface; Risk

2011
Role of genetic variation in regulation of aldosterone biosynthesis.
    Endocrine development, 2011, Volume: 20

    Topics: Aldosterone; Animals; Cardiovascular Diseases; Cytochrome P-450 CYP11B2; Genetic Variation; Humans;

2011
The kidneys and aldosterone/mineralocorticoid receptor system in salt-sensitive hypertension.
    Current hypertension reports, 2011, Volume: 13, Issue:2

    Topics: Aldosterone; Humans; Hypertension; Kidney; Receptors, Mineralocorticoid; Signal Transduction; Sodium

2011
Hypertension due to loss of clock: novel insight from the molecular analysis of Cry1/Cry2-deleted mice.
    Current hypertension reports, 2011, Volume: 13, Issue:2

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Biological Clocks; Circadian Rhythm; CLOCK Pr

2011
Mineralocorticoid actions in the brain and hypertension.
    Current hypertension reports, 2011, Volume: 13, Issue:3

    Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Brain; Cerebrospinal Fluid; Cytochrome P-450 C

2011
Antihypertensive therapy for patients with obstructive sleep apnea.
    Current opinion in nephrology and hypertension, 2011, Volume: 20, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Continuous Positive Airway Pressure; Humans; Hypertension; Inc

2011
Antihypertensive therapy for patients with obstructive sleep apnea.
    Current opinion in nephrology and hypertension, 2011, Volume: 20, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Continuous Positive Airway Pressure; Humans; Hypertension; Inc

2011
Antihypertensive therapy for patients with obstructive sleep apnea.
    Current opinion in nephrology and hypertension, 2011, Volume: 20, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Continuous Positive Airway Pressure; Humans; Hypertension; Inc

2011
Antihypertensive therapy for patients with obstructive sleep apnea.
    Current opinion in nephrology and hypertension, 2011, Volume: 20, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Continuous Positive Airway Pressure; Humans; Hypertension; Inc

2011
Aldosterone, hypertension, and beyond.
    Iranian journal of kidney diseases, 2011, Volume: 5, Issue:2

    Topics: Aldosterone; Epigenomics; Epithelial Sodium Channels; Humans; Hyperaldosteronism; Hypertension; Hypo

2011
Mineralocorticoid receptor blockade in chronic kidney disease.
    Current hypertension reports, 2011, Volume: 13, Issue:4

    Topics: Aldosterone; Diabetes Mellitus; Humans; Hypertension; Inflammation; Kidney Failure, Chronic; Mineral

2011
Envoi.
    Reviews in endocrine & metabolic disorders, 2011, Volume: 12, Issue:1

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

2011
Role of mineralocorticoid action in the brain in salt-sensitive hypertension.
    Clinical and experimental pharmacology & physiology, 2012, Volume: 39, Issue:1

    Topics: Aldosterone; Animals; Brain; Central Nervous System; Humans; Hypertension; Ligands; Mineralocorticoi

2012
[Non-steroidal anti-inflammatory drugs and risk of stroke in older patients: current controversies and research directions].
    Giornale italiano di cardiologia (2006), 2011, Volume: 12, Issue:5

    Topics: Age Factors; Aged; Aged, 80 and over; Aldosterone; Anti-Inflammatory Agents, Non-Steroidal; Atherosc

2011
Resistant hypertension, obstructive sleep apnoea and aldosterone.
    Journal of human hypertension, 2012, Volume: 26, Issue:5

    Topics: Airway Resistance; Aldosterone; Antihypertensive Agents; Blood Pressure; Comorbidity; Continuous Pos

2012
Mutations in KCNJ5 gene cause hyperaldosteronism.
    Circulation research, 2011, Jun-10, Volume: 108, Issue:12

    Topics: Adenoma; Aldosterone; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Humans; Hype

2011
Luminal nucleotides are tonic inhibitors of renal tubular transport.
    Current opinion in nephrology and hypertension, 2011, Volume: 20, Issue:5

    Topics: Adenosine Triphosphate; Aldosterone; Animals; Blood Pressure; Cilia; Connexins; Epithelial Cells; Hu

2011
Role of BK channels in hypertension and potassium secretion.
    Current opinion in nephrology and hypertension, 2011, Volume: 20, Issue:5

    Topics: Aldosterone; Animals; Blood Pressure; Humans; Hypertension; Ion Transport; Kidney Tubules; Large-Con

2011
[Renin-angiotensin-aldosteron system: evolution of views from renin discovery to nowadays. Perspectives of therapeutic block].
    Terapevticheskii arkhiv, 2011, Volume: 83, Issue:4

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Humans; Hypertension; Mineraloc

2011
Arterial hypertension and thyroid disorders: what is important to know in clinical practice?
    Annales d'endocrinologie, 2011, Volume: 72, Issue:4

    Topics: Adrenergic beta-Antagonists; Aldosterone; Animals; Antihypertensive Agents; Calcium Channel Blockers

2011
Emerging drugs which target the renin-angiotensin-aldosterone system.
    Expert opinion on emerging drugs, 2011, Volume: 16, Issue:4

    Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Clinical Trials as Topic; Drug Design; Drugs,

2011
Regulation and dysregulation of epithelial Na+ channels.
    Clinical and experimental nephrology, 2012, Volume: 16, Issue:1

    Topics: Aldosterone; Animals; Epithelial Sodium Channels; Extracellular Signal-Regulated MAP Kinases; Gene E

2012
Effects of low-sodium diet vs. high-sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride (Cochrane Review).
    American journal of hypertension, 2012, Volume: 25, Issue:1

    Topics: Adult; Aged; Aldosterone; Asian People; Black People; Blood Pressure; Catecholamines; Cholesterol; D

2012
Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride.
    The Cochrane database of systematic reviews, 2011, Nov-09, Issue:11

    Topics: Aldosterone; Asian People; Black People; Blood Pressure; Catecholamines; Cholesterol; Diet, Sodium-R

2011
Primary aldosteronism: who should be screened?
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2012, Volume: 44, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Practice Guidelines as Topic

2012
[Bone and calcium update; research of calcium metabolism on cardiovascular system update. Calcium channel blocker update].
    Clinical calcium, 2011, Volume: 21, Issue:12

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Calcium Channels; C

2011
M-atrial natriuretic peptide: a novel antihypertensive protein therapy.
    Current hypertension reports, 2012, Volume: 14, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Biological Availability; Blood Pres

2012
Prevalence of primary aldosteronism in patient's cohorts and in population-based studies--a review of the current literature.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2012, Volume: 44, Issue:3

    Topics: Aldosterone; Cohort Studies; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Population Gr

2012
Intrinsic control of sodium excretion in the distal nephron by inhibitory purinergic regulation of the epithelial Na(+) channel.
    Current opinion in nephrology and hypertension, 2012, Volume: 21, Issue:1

    Topics: Aldosterone; Animals; Biological Transport; Blood Pressure; Epithelial Sodium Channels; Humans; Hype

2012
Inflammation in hypertension: current therapeutic approaches.
    Current pharmaceutical design, 2011, Volume: 17, Issue:37

    Topics: Adipose Tissue; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; Cell Adhe

2011
Extrarenal effects of aldosterone.
    Current opinion in nephrology and hypertension, 2012, Volume: 21, Issue:2

    Topics: Aldosterone; Endothelium, Vascular; Heart; Humans; Hypertension; Inflammation; Metabolic Syndrome; M

2012
Mineralocorticoid receptor-associated hypertension and its organ damage: clinical relevance for resistant hypertension.
    American journal of hypertension, 2012, Volume: 25, Issue:5

    Topics: Aldosterone; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hypertension; Receptors, Mine

2012
[Mechanisms responsible for the renoprotective effects of renin-angiotensin inhibitors].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2012, Volume: 132, Issue:4

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Humans; Hypertension;

2012
Resistant hypertension and aldosterone: an update.
    The Canadian journal of cardiology, 2012, Volume: 28, Issue:3

    Topics: Aldosterone; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Hyperaldosteronis

2012
Aldosterone, oxidative stress, and NF-κB activation in hypertension-related cardiovascular and renal diseases.
    Free radical biology & medicine, 2012, Jul-15, Volume: 53, Issue:2

    Topics: Aldosterone; Animals; Cardiovascular Diseases; Disease Models, Animal; Heart Failure; Humans; Hypera

2012
Pathophysiology of salt sensitivity hypertension.
    Annals of medicine, 2012, Volume: 44 Suppl 1

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Kidney; Protein Serine-Threonine Kinases; rac1 GT

2012
Salt, aldosterone and hypertension.
    Journal of human hypertension, 2013, Volume: 27, Issue:1

    Topics: Aldosterone; Animals; Appetite; Cardiovascular Diseases; Humans; Hyperaldosteronism; Hypertension; K

2013
Integrating genetics and genomics in primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:3

    Topics: Aldosterone; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Genomics; Humans; Hyperaldost

2012
The ubiquitous mineralocorticoid receptor: clinical implications.
    Current hypertension reports, 2012, Volume: 14, Issue:6

    Topics: Aldosterone; Cardiovascular Diseases; Glucocorticoids; Humans; Hypertension; Mineralocorticoid Recep

2012
Circadian clock-deficient mice as a tool for exploring disease etiology.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:9

    Topics: Aldosterone; Animals; Circadian Clocks; Circadian Rhythm; Cryptochromes; Diabetes Mellitus; Humans;

2012
Aldosterone synthase inhibition in humans.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2013, Volume: 28, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Humans; Hypertens

2013
[Update on endocrine hypertension].
    Annales d'endocrinologie, 2012, Volume: 73 Suppl 1

    Topics: Adrenal Gland Neoplasms; Adrenocortical Adenoma; Aldosterone; Cardiovascular Diseases; Endocrine Sys

2012
Effects of angiotensin II on kinase-mediated sodium and potassium transport in the distal nephron.
    Current opinion in nephrology and hypertension, 2013, Volume: 22, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Epithelial Sodium Channels; Humans; Hyperkalemia; Hypertension

2013
[Primay hyperaldosteronism--diagnostic and treatment].
    Deutsche medizinische Wochenschrift (1946), 2012, Volume: 137, Issue:48

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocortical Adenoma; A

2012
Vascular actions of aldosterone.
    Journal of vascular research, 2013, Volume: 50, Issue:2

    Topics: Adipocytes; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Vessels; Cardiovasc

2013
[Resistant hypertension].
    Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina), 2012, Volume: 69, Issue:3

    Topics: Age Factors; Aldosterone; Coronary Vasospasm; Disease Management; Diuretics; Humans; Hyperaldosteron

2012
Aldosterone and the risk of hypertension.
    Current hypertension reports, 2013, Volume: 15, Issue:2

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Renin

2013
Mineralocorticoid receptors and pathophysiological roles for aldosterone in the cardiovascular system.
    Journal of hypertension, 2002, Volume: 20, Issue:8

    Topics: Aldosterone; Animals; Cardiomegaly; Cardiovascular System; Heart Failure; Humans; Hyperaldosteronism

2002
[Aldosterone and cardiovascular diseases, more than water and salt retention].
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 2002, Volume: 64, Issue:3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Body Water; Cardiovascular Di

2002
New genetic insights in familial hyperaldosteronism.
    Annals of the New York Academy of Sciences, 2002, Volume: 970

    Topics: Adrenal Cortex Diseases; Aldosterone; Chromosomes, Human, Pair 7; Cytochrome P-450 CYP11B2; Humans;

2002
Primary aldosteronism: management issues.
    Annals of the New York Academy of Sciences, 2002, Volume: 970

    Topics: Adrenal Cortex Diseases; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypok

2002
New biology of aldosterone, and experimental studies on the selective aldosterone blocker eplerenone.
    American heart journal, 2002, Volume: 144, Issue:5 Suppl

    Topics: Aldosterone; Animals; Cardiomegaly; Clinical Trials as Topic; Desoxycorticosterone; Eplerenone; Fibr

2002
Clinical implications of aldosterone blockade.
    American heart journal, 2002, Volume: 144, Issue:5 Suppl

    Topics: Aldosterone; Antihypertensive Agents; Black People; Blood Pressure; Cardiovascular Diseases; Clinica

2002
The role of aldosterone receptor blockade in the management of cardiovascular disease.
    Current opinion in investigational drugs (London, England : 2000), 2002, Volume: 3, Issue:10

    Topics: Aldosterone; Animals; Cardiovascular Diseases; Eplerenone; Heart Failure; Humans; Hypertension; Mine

2002
Local cardiac renin-angiotensin system: hypertension and cardiac failure.
    Journal of molecular and cellular cardiology, 2002, Volume: 34, Issue:11

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically

2002
Aldosterone-induced cardiac damage: focus on blood pressure independent effects.
    American journal of hypertension, 2003, Volume: 16, Issue:1

    Topics: Aldosterone; Animals; Blood Pressure; Cardiomyopathies; Heart Failure; Hyperaldosteronism; Hypertens

2003
Aldosterone: a risk factor for vascular disease.
    Current hypertension reports, 2003, Volume: 5, Issue:1

    Topics: Aldosterone; Animals; Arteries; Fibrosis; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoi

2003
Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglyceride.
    The Cochrane database of systematic reviews, 2003, Issue:1

    Topics: Aldosterone; Blood Pressure; Catecholamines; Cholesterol; Diet, Sodium-Restricted; Humans; Hypertens

2003
Essential hypertension and left ventricular hypertrophy in cardiovascular disease: beyond overactivity of the renin-angiotensin-aldosterone-sodium system.
    Journal of hypertension, 2003, Volume: 21, Issue:2

    Topics: Aldosterone; Animals; Cardiovascular Diseases; Humans; Hypertension; Hypertrophy, Left Ventricular;

2003
Eplerenone.
    Nature reviews. Drug discovery, 2003, Volume: 2, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Clinical Trials as Topic; Drug Approval; Eplerenone; Humans; H

2003
Aldosterone and specific aldosterone receptor antagonists in hypertension and cardiovascular disease.
    Current hypertension reports, 2003, Volume: 5, Issue:2

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Diseases; Endothelium

2003
Is altered adrenal steroid biosynthesis a key intermediate phenotype in hypertension?
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:5

    Topics: Adrenal Glands; Aldosterone; Cytochrome P-450 CYP11B2; Humans; Hyperaldosteronism; Hypertension; Phe

2003
Negative regulators of sodium transport in the kidney: key factors in understanding salt-sensitive hypertension?
    The Journal of clinical investigation, 2003, Volume: 111, Issue:7

    Topics: Aldosterone; Animals; Biological Transport; Blood Pressure; Humans; Hypertension; Hypotension; Kidne

2003
[Monogenic hypertension].
    Medizinische Klinik (Munich, Germany : 1983), 2003, Apr-15, Volume: 98, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Child; Female; Genes, Dominant; Genotype; Humans; Hyperaldosteronism

2003
Eplerenone: cardiovascular protection.
    Circulation, 2003, May-20, Volume: 107, Issue:19

    Topics: Aldosterone; Animals; Cardiovascular Diseases; Cardiovascular System; Disease Models, Animal; Eplere

2003
[Role of ion channels of kidney in water-electrolyte metabolism].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2003, May-10, Volume: 92, Issue:5

    Topics: Aldosterone; Alkalosis; Animals; Bartter Syndrome; Chloride Channels; Humans; Hyperaldosteronism; Hy

2003
Forms of mineralocorticoid hypertension.
    Vitamins and hormones, 2003, Volume: 66

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction;

2003
Aldosterone breakthrough during angiotensin-converting enzyme inhibitor therapy.
    American journal of hypertension, 2003, Volume: 16, Issue:9 Pt 1

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Clinical Trials as Topic; Diu

2003
[Primary hyperaldosteronism].
    Nederlands tijdschrift voor geneeskunde, 2003, Aug-16, Volume: 147, Issue:33

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Antihypertensive Agent

2003
Aldosterone receptor antagonists for hypertension: what do they offer?
    Drugs, 2003, Volume: 63, Issue:19

    Topics: Aldosterone; Clinical Trials as Topic; Diuretics; Eplerenone; Heart Failure; Humans; Hypertension; M

2003
[ALDOSTERONE AND HYPERTENSION].
    Polskie Archiwum Medycyny Wewnetrznej, 1963, Volume: 33

    Topics: Aldosterone; Humans; Hypertension

1963
[THE EFFECT OF POSTURAL CHANGES ON THE PHYSIOLOGICAL FUNCTION IN MAN].
    Showa Igakkai zasshi = The Journal of the Showa Medical Association, 1963, Volume: 23

    Topics: Aldosterone; Cardiovascular System; Epinephrine; Hexamethonium Compounds; Humans; Hypertension; Hypo

1963
[DRUGS INHIBITING ALDOSTERONE SECRETION AND ALDOSTERONE ANTAGONISTS].
    [Sogo rinsho] Clinic all-round, 1963, Volume: 12

    Topics: Aldosterone; Edema; Heparinoids; Hypertension; Ketones; Metyrapone; Mineralocorticoid Receptor Antag

1963
[ANGIOTENSIN AND ALDOSTERONE SECRETION].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1963, Volume: 8

    Topics: Aldosterone; Angiotensins; Biological Transport; Chemical Phenomena; Chemistry; Hypertension; Pharma

1963
CHEMISTRY AND THERAPY OF MALIGNANT HYPERTENSION.
    Biochemical clinics, 1963, Volume: 2

    Topics: Aldosterone; Angiotensins; Antihypertensive Agents; Blood Vessels; Cushing Syndrome; Glomerulonephri

1963
MECHANISMS IN ESSENTIAL HYPERTENSION.
    Diseases of the chest, 1964, Volume: 45

    Topics: Aldosterone; Angiotensins; Catecholamines; Essential Hypertension; Guanethidine; Hypertension; Miner

1964
SYSTEMIC CIRCULATION.
    Annual review of physiology, 1964, Volume: 26

    Topics: Aldosterone; Angiotensins; Blood Circulation; Blood Vessels; Blood Viscosity; Blood Volume; Blood Vo

1964
ALDOSTERONISM.
    Disease-a-month : DM, 1964, Volume: 45

    Topics: Aldosterone; Diagnosis, Differential; Diuretics; Humans; Hyperaldosteronism; Hypertension; Kidney Di

1964
ALDOSTERONE AND ANGIOTENSIN. INTERRELATIONSHIPS IN NORMAL AND DISEASED STATES.
    JAMA, 1964, Jun-22, Volume: 188

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensins; Desoxycorticosterone; Digoxin; Dogs; Heart F

1964
ALDOSTERONE: ITS BIOCHEMISTRY AND PHYSIOLOGY.
    Advances in metabolic disorders, 1964, Volume: 15

    Topics: Aldosterone; Angiotensins; Biochemical Phenomena; Biochemistry; Blood; Edema; Female; Homeostasis; H

1964
[METABOLIC DATA ON HYPERTENSION (ESSENTIAL HYPERTENSION)].
    Lekarska veda v zahranici, 1964, Aug-21, Volume: 22

    Topics: Adrenal Glands; Aldosterone; Angiotensins; Arteriosclerosis; Autonomic Nervous System Diseases; Cate

1964
ALDOSTERONE IN CLINICAL MEDICINE.
    California medicine, 1964, Volume: 101

    Topics: Aldosterone; Blood Volume; Body Weight; Desoxycorticosterone; Dexamethasone; Diuretics; Drug Therapy

1964
RECENT ADVANCES IN HYPERTENSION.
    Canadian Medical Association journal, 1964, Oct-31, Volume: 91

    Topics: Aldosterone; Angiotensins; Blood Pressure; Cardiac Output; Hypertension; Hypertension, Renal; Kidney

1964
[PHYSIOPATHOLOGY OF ARTERIAL HYPERTENSION. ROLE OF ANGIOTENSIN AND ALDOSTERONE SECRETION].
    La Presse medicale, 1964, Dec-12, Volume: 72

    Topics: Adrenal Glands; Aldosterone; Angiotensins; Biochemical Phenomena; Biochemistry; Hyperaldosteronism;

1964
[NEW DATA ON THE ETIOPATHOGENESIS OF ESSENTIAL ARTERIAL HYPERTENSION].
    Studii si cercetari de medicina interna, 1965, Volume: 40

    Topics: Aldosterone; Electrolytes; Essential Hypertension; Humans; Hypertension; Metabolism

1965
Aldosterone blockade in patients with systolic left ventricular dysfunction.
    Circulation, 2003, Oct-14, Volume: 108, Issue:15

    Topics: Aldosterone; Eplerenone; Forecasting; Heart Failure; Humans; Hypercholesterolemia; Hypertension; Mal

2003
Aldosterone receptor antagonists: biology and novel therapeutical applications.
    Journal of endocrinological investigation, 2003, Volume: 26, Issue:8

    Topics: Aldosterone; Heart Failure; Hirsutism; Humans; Hyperaldosteronism; Hypertension; Liver Cirrhosis; Mi

2003
Primary aldosteronism.
    Best practice & research. Clinical endocrinology & metabolism, 2003, Volume: 17, Issue:4

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Diagnosis, Differential; Humans; Hyperaldoster

2003
[The aldosterone to Renin ratio in secondary hypertension].
    Herz, 2003, Volume: 28, Issue:8

    Topics: Adrenalectomy; Adult; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension

2003
A neuroendocrine-immune interface. The immunostimulatory state of aldosteronism.
    Herz, 2003, Volume: 28, Issue:8

    Topics: Aldosterone; Antioxidants; Cytokines; Endomyocardial Fibrosis; Heart Failure; Humans; Hyperaldostero

2003
[Rational diagnostic approach in hypertension].
    Praxis, 2003, Dec-03, Volume: 92, Issue:49

    Topics: Adrenal Gland Neoplasms; Aldosterone; Angiography; Cushing Syndrome; Diabetic Nephropathies; Diagnos

2003
Obesity and hypertension.
    Endocrinology and metabolism clinics of North America, 2003, Volume: 32, Issue:4

    Topics: Adipose Tissue; Aldosterone; Body Mass Index; Cardiovascular System; Genetic Predisposition to Disea

2003
Hypertension and obesity.
    Recent progress in hormone research, 2004, Volume: 59

    Topics: Adipose Tissue; Aldosterone; Animals; Body Mass Index; Humans; Hypertension; Inflammation; Insulin R

2004
Hypertension and obesity.
    Recent progress in hormone research, 2004, Volume: 59

    Topics: Adipose Tissue; Aldosterone; Animals; Body Mass Index; Humans; Hypertension; Inflammation; Insulin R

2004
Hypertension and obesity.
    Recent progress in hormone research, 2004, Volume: 59

    Topics: Adipose Tissue; Aldosterone; Animals; Body Mass Index; Humans; Hypertension; Inflammation; Insulin R

2004
Hypertension and obesity.
    Recent progress in hormone research, 2004, Volume: 59

    Topics: Adipose Tissue; Aldosterone; Animals; Body Mass Index; Humans; Hypertension; Inflammation; Insulin R

2004
Fibrosis in hypertensive heart disease: role of the renin-angiotensin-aldosterone system.
    The Medical clinics of North America, 2004, Volume: 88, Issue:1

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Collagen; Fibrosis;

2004
Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglyceride.
    The Cochrane database of systematic reviews, 2004, Issue:1

    Topics: Aldosterone; Blood Pressure; Catecholamines; Cholesterol; Diet, Sodium-Restricted; Humans; Hypertens

2004
[Significance of aldosterone antagonist therapy].
    Der Internist, 2004, Volume: 45, Issue:3

    Topics: Aldosterone; Cardiovascular Diseases; Clinical Trials as Topic; Dose-Response Relationship, Drug; Dr

2004
Trends in the prevalence of primary aldosteronism, aldosterone-producing adenomas, and surgically correctable aldosterone-dependent hypertension.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:4

    Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Remission Induction

2004
Evolving role of aldosterone blockers alone and in combination with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers in hypertension management: a review of mechanistic and clinical data.
    American heart journal, 2004, Volume: 147, Issue:4

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bloo

2004
Pathogenesis of structural vascular changes in hypertension.
    Journal of hypertension, 2004, Volume: 22, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Obesity; Sodium Chloride

2004
Genetics of primary aldosteronism.
    Journal of hypertension, 2004, Volume: 22, Issue:4

    Topics: Aldosterone; Cytochrome P-450 CYP11B2; Gene Expression Regulation; Genetic Variation; Genetics; Huma

2004
Aldosterone and aldosterone antagonism in systemic hypertension.
    Current hypertension reports, 2004, Volume: 6, Issue:3

    Topics: Aldosterone; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hypertension; Mineralocortico

2004
Regulation of epithelial ion transport by aldosterone through changes in gene expression.
    Molecular and cellular endocrinology, 2004, Mar-31, Volume: 217, Issue:1-2

    Topics: Aldosterone; Anti-Inflammatory Agents; Biological Transport, Active; Cortisone; Epithelial Cells; Ex

2004
Aldosterone target organ protection by eplerenone.
    Molecular and cellular endocrinology, 2004, Mar-31, Volume: 217, Issue:1-2

    Topics: Aldosterone; Blood Vessels; Brain; Clinical Trials as Topic; Eplerenone; Heart Failure; Humans; Hype

2004
The impact of polymorphisms in the gene encoding aldosterone synthase (CYP11B2) on steroid synthesis and blood pressure regulation.
    Molecular and cellular endocrinology, 2004, Mar-31, Volume: 217, Issue:1-2

    Topics: Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Cortodoxone; Cytochrome P-450 CYP11B2; Gen

2004
[Hypertension secondary to primary aldosteronism].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Diagnosis, Di

2004
Brain mineralocorticoid receptors: orchestrators of hypertension and end-organ disease.
    Current opinion in nephrology and hypertension, 2004, Volume: 13, Issue:2

    Topics: Aldosterone; Brain; Disease; Heart; Humans; Hypertension; Kidney; Receptors, Mineralocorticoid

2004
Mechanisms of obesity-related hypertension.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2004, Volume: 36, Issue:6

    Topics: Adipose Tissue; Adrenal Glands; Aldosterone; Fatty Acids; Humans; Hypertension; Hypothalamus; Liver;

2004
Role of aldosterone blockade in the management of hypertension and cardiovascular disease.
    Contributions to nephrology, 2004, Volume: 143

    Topics: Aldosterone; Animals; Heart Failure; Humans; Hypertension; Kidney Diseases; Mineralocorticoid Recept

2004
Mineralocorticoid receptor antagonists and hypertension: is there a rationale?
    Current hypertension reports, 2004, Volume: 6, Issue:4

    Topics: Albuminuria; Aldosterone; Animals; Drug Therapy, Combination; Eplerenone; Humans; Hyperkalemia; Hype

2004
Effect of longer-term modest salt reduction on blood pressure.
    The Cochrane database of systematic reviews, 2004, Issue:3

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Lipids; Norepinephrine; Randomized Controlled Tri

2004
Effect of longer-term modest salt reduction on blood pressure.
    The Cochrane database of systematic reviews, 2004, Issue:3

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Lipids; Norepinephrine; Randomized Controlled Tri

2004
Effect of longer-term modest salt reduction on blood pressure.
    The Cochrane database of systematic reviews, 2004, Issue:3

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Lipids; Norepinephrine; Randomized Controlled Tri

2004
Effect of longer-term modest salt reduction on blood pressure.
    The Cochrane database of systematic reviews, 2004, Issue:3

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Lipids; Norepinephrine; Randomized Controlled Tri

2004
Capsaicin sensitive-sensory nerves and blood pressure regulation.
    Current medicinal chemistry. Cardiovascular and hematological agents, 2003, Volume: 1, Issue:2

    Topics: Aldosterone; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Capsaicin;

2003
[Diagnosis and treatment of primary hyperaldosteronism].
    Khirurgiia, 2004, Issue:3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Chronic Disease; Diagnosis, Differential; Hum

2004
[Renin-angiotensin-aldosterone system and natriuretic peptide system--reference to cardiovascular diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 9

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiovascular Diseases; Drug Design; Heart Fa

2004
Arterial stiffness and the renin-angiotensin-aldosterone system.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2004, Volume: 5, Issue:3

    Topics: Aldosterone; Arteries; Elasticity; Humans; Hypertension; Renin-Angiotensin System

2004
Obesity-associated hypertension: new insights into mechanisms.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:1

    Topics: Adiponectin; Aldosterone; Animals; Appetite; Endothelium, Vascular; Energy Metabolism; Ghrelin; Huma

2005
Plasma renin and aldosterone measurements in low renin hypertensive states.
    Trends in endocrinology and metabolism: TEM, 2005, Volume: 16, Issue:3

    Topics: Aldosterone; Blood Chemical Analysis; Humans; Hypertension; Renin; Sensitivity and Specificity

2005
Aldosterone as a cardiovascular risk factor.
    Trends in endocrinology and metabolism: TEM, 2005, Volume: 16, Issue:3

    Topics: Aldosterone; Animals; Cardiac Output, Low; Cardiovascular Diseases; Humans; Hypertension; Mineraloco

2005
Genetics of human hypertension.
    Trends in endocrinology and metabolism: TEM, 2005, Volume: 16, Issue:3

    Topics: Aldosterone; Genetic Linkage; Humans; Hypertension; Polymorphism, Genetic; Renin-Angiotensin System

2005
[Blockade of renin-angiotensin system and aldosterone breakthrough].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 3

    Topics: Aldosterone; Animals; Humans; Hypertension; Renin-Angiotensin System

2005
Pleiotropic actions of aldosterone and the effects of eplerenone, a selective mineralocorticoid receptor antagonist.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:11

    Topics: Aldosterone; Animals; Drug Interactions; Eplerenone; Humans; Hypertension; Mineralocorticoid Recepto

2004
Mineralocorticoid resistance.
    Clinical endocrinology, 2005, Volume: 62, Issue:5

    Topics: Aldosterone; Genes, Dominant; Genes, Recessive; Genotype; Humans; Hypertension; Kidney; Mineralocort

2005
Cardiovascular effects of aldosterone.
    Bratislavske lekarske listy, 2005, Volume: 106, Issue:1

    Topics: Aldosterone; Animals; Cardiovascular Diseases; Heart Failure; Humans; Hypertension; Mineralocorticoi

2005
Aldosterone receptor antagonists: biology and novel therapeutic applications.
    Current hypertension reports, 2005, Volume: 7, Issue:3

    Topics: Aldosterone; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Ant

2005
[Hypertension due to primary aldosteronism].
    Revue medicale de Liege, 2005, Volume: 60, Issue:4

    Topics: Aldosterone; Decision Trees; Humans; Hyperaldosteronism; Hypertension

2005
[Aldosterone blockade in essential hypertension].
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2005, Volume: 6 Suppl 1

    Topics: Aldosterone; Fibrosis; Humans; Hypertension; Inflammation; Mineralocorticoid Receptor Antagonists

2005
Role of cardiovascular aldosterone in hypertension.
    Current medicinal chemistry. Cardiovascular and hematological agents, 2005, Volume: 3, Issue:3

    Topics: Aldosterone; Animals; Cardiovascular System; Epithelial Cells; Humans; Hypertension

2005
Antihypertensive therapy: role of aldosterone antagonists.
    Current pharmaceutical design, 2005, Volume: 11, Issue:17

    Topics: Aldosterone; Animals; Antihypertensive Agents; Humans; Hypertension; Mineralocorticoid Receptor Anta

2005
[Roll of aldosterone in pathogenesis of kidney disorders].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2005, Jul-10, Volume: 94, Issue:7

    Topics: Aldosterone; Animals; Body Water; Disease Models, Animal; Eplerenone; Humans; Hypertension; Kidney D

2005
Molecular mechanisms of mineralocorticoid receptor antagonism by eplerenone.
    Mini reviews in medicinal chemistry, 2005, Volume: 5, Issue:8

    Topics: Aldosterone; Animals; Eplerenone; Heart Failure; Hypertension; Ligands; Mineralocorticoid Receptor A

2005
Treatment of resistant hypertension.
    Current hypertension reports, 2005, Volume: 7, Issue:5

    Topics: Aldosterone; Algorithms; Antihypertensive Agents; Drug Resistance; Hemodynamics; Humans; Hypertensio

2005
Miscellaneous endocrine causes of hypertension.
    Current cardiology reports, 2005, Volume: 7, Issue:6

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Biomarkers; Humans; Hyperaldoster

2005
Mineralocorticoid-stimulating activity of adipose tissue.
    Best practice & research. Clinical endocrinology & metabolism, 2005, Volume: 19, Issue:4

    Topics: Adipocytes; Adipose Tissue; Aldosterone; Blood Pressure; Humans; Hypertension; Mineralocorticoids; O

2005
Aldosterone--a hormone of cardiovascular adaptation and maladaptation.
    Journal of clinical hypertension (Greenwich, Conn.), 2006, Volume: 8, Issue:2

    Topics: Aldosterone; Blood Pressure; Cardiovascular Diseases; Electrolytes; Homeostasis; Humans; Hypertensio

2006
[Molecular mechanism in biological transport in the kidney: Na+/K(+)-ATPase].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 2

    Topics: Aldosterone; Biological Transport; Calmodulin-Binding Proteins; Catecholamines; Hypertension; Insuli

2006
Mineralocorticoid receptor blockade in the protection of target organ damage.
    Cardiovascular & hematological agents in medicinal chemistry, 2006, Volume: 4, Issue:1

    Topics: Aldosterone; Animals; Brain; Brain Diseases; Cardiovascular Diseases; Eplerenone; Heart; Humans; Hyp

2006
The role of aldosterone in renal sodium transport.
    Seminars in nephrology, 2006, Volume: 26, Issue:2

    Topics: Aldosterone; Biological Transport; Blood Pressure; Humans; Hypertension; Nephrons; Sodium

2006
The pharmacological treatment of primary aldosteronism.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:5

    Topics: Aldosterone; Amiloride; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combinatio

2006
Inherited sodium avid states.
    Advances in chronic kidney disease, 2006, Volume: 13, Issue:2

    Topics: Aldosterone; Genetic Predisposition to Disease; Humans; Hypertension; Nephrons; Renin; Sodium; Sodiu

2006
Optimal use and interpretation of the aldosterone renin ratio to detect aldosterone excess in hypertension.
    Journal of human hypertension, 2006, Volume: 20, Issue:7

    Topics: Aldosterone; Antihypertensive Agents; Captopril; Humans; Hyperaldosteronism; Hypertension; Renin; Se

2006
Role of the renin-angiotensin-aldosterone system in vascular remodeling and inflammation: a clinical review.
    Journal of hypertension, 2006, Volume: 24, Issue:6

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2006
[Regulation by vasopressin of NaCl absorption in the renal collecting duct].
    Journal de la Societe de biologie, 2005, Volume: 199, Issue:4

    Topics: Absorption; Aldosterone; Amiloride; Animals; Cells, Cultured; Chlorides; Cystic Fibrosis Transmembra

2005
The renal epithelial sodium channel: genetic heterogeneity and implications for the treatment of high blood pressure.
    Current pharmaceutical design, 2006, Volume: 12, Issue:18

    Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Endosomal Sorting Complexes Required for Transport;

2006
[Prostasin].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 5

    Topics: Aldosterone; Amyloid beta-Protein Precursor; Animals; Benzamidines; Epithelial Sodium Channels; Guan

2006
[Nitric oxide].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 5

    Topics: Adiponectin; Aldosterone; Animals; Arginine; Blood Pressure; Cardiovascular Diseases; Endothelium, V

2006
Hypertension and diabetes: role of the renin-angiotensin system.
    Endocrinology and metabolism clinics of North America, 2006, Volume: 35, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Cardiovascular Diseases; Diabetes Complications; Diabetes Mell

2006
Screening for primary aldosteronism.
    Best practice & research. Clinical endocrinology & metabolism, 2006, Volume: 20, Issue:3

    Topics: Aldosterone; Algorithms; Humans; Hyperaldosteronism; Hypertension; Potassium; Prevalence; Renin

2006
Surgically correctable hypertension caused by primary aldosteronism.
    Best practice & research. Clinical endocrinology & metabolism, 2006, Volume: 20, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Algorit

2006
Incidentally discovered masses in hypertensive patients.
    Best practice & research. Clinical endocrinology & metabolism, 2006, Volume: 20, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cushing Syndrome; Diagnostic Imaging; Humans; Hyperte

2006
[Normokalemic primary hyperaldosteronism].
    Deutsche medizinische Wochenschrift (1946), 2006, Volume: 131, Issue:46 Spec No

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hype

2006
Association of the C-344T aldosterone synthase gene variant with essential hypertension: a meta-analysis.
    Journal of hypertension, 2007, Volume: 25, Issue:1

    Topics: Aldosterone; Blood Pressure; Case-Control Studies; Cohort Studies; Cross-Sectional Studies; Cytochro

2007
Hypertension and the expanding role of aldosterone.
    Current hypertension reports, 2006, Volume: 8, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Humans; Hypertension

2006
Aldosterone breakthrough during RAS blockade: a role for endothelins and their antagonists?
    Current hypertension reports, 2006, Volume: 8, Issue:3

    Topics: Adrenal Cortex; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2006
Primary hyperaldosteronism secondary to unilateral adrenal hyperplasia: an unusual cause of surgically correctable hypertension. A review of 30 cases.
    World journal of surgery, 2007, Volume: 31, Issue:1

    Topics: Adrenal Glands; Aldosterone; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; Male; Mi

2007
Resistant hypertension: prevalence and evolving concepts.
    Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:1 Suppl 1

    Topics: Aldosterone; Humans; Hypertension; Prevalence; Recurrence; Sleep Apnea, Obstructive; Treatment Failu

2007
Aldosterone and the vasculature: mechanisms mediating resistant hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:1 Suppl 1

    Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Endothelium; Humans; Hypertension; Muscle, Sm

2007
[Diagnosis of primary hyperaldosteronism].
    Medizinische Klinik (Munich, Germany : 1983), 2007, Jan-15, Volume: 102, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia

2007
[Screening tests and diagnostic examinations of hypertensives for primary aldosteronism].
    Rinsho byori. The Japanese journal of clinical pathology, 2006, Volume: 54, Issue:11

    Topics: Adrenal Cortex Function Tests; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Antihyperten

2006
Genetics of arterial hypertension and hypotension.
    Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 374, Issue:5-6

    Topics: Aldosterone; Blood Pressure; Genetic Predisposition to Disease; Humans; Hydrocortisone; Hypertension

2007
Ca2+ channel subtypes and pharmacology in the kidney.
    Circulation research, 2007, Feb-16, Volume: 100, Issue:3

    Topics: Aldosterone; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Calcium Channel Blockers;

2007
Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions.
    Clinical science (London, England : 1979), 2007, Volume: 112, Issue:7

    Topics: Aldosterone; Angiotensin II; Cell Adhesion Molecules; Cytokines; Diabetes Complications; Diabetes Me

2007
Aldosterone excess, hypertension, and chromosome 7p22: evidence continues to mount.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:4

    Topics: Aldosterone; Chromosome Mapping; Chromosomes, Human, Pair 7; Genetic Linkage; Humans; Hypertension

2007
Angiotensin II reactivation and aldosterone escape phenomena in renin-angiotensin-aldosterone system blockade: is oral renin inhibition the solution?
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:5

    Topics: Administration, Oral; Aldosterone; Amides; Angiotensin II; Animals; Antihypertensive Agents; Enzyme

2007
New concepts in adrenal vein sampling for aldosterone in the diagnosis of primary aldosteronism.
    Current hypertension reports, 2007, Volume: 9, Issue:2

    Topics: Adrenal Glands; Aldosterone; Blood Pressure; Diagnosis, Differential; Humans; Hyperaldosteronism; Hy

2007
The role of aldosterone in resistant hypertension: implications for pathogenesis and therapy.
    Current hypertension reports, 2007, Volume: 9, Issue:2

    Topics: Aldosterone; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Mi

2007
Why are mineralocorticoid receptors so nonselective?
    Current hypertension reports, 2007, Volume: 9, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Blood Pressure; Humans; Hydrocortisone; Hy

2007
The emerging role of ACE2 in physiology and disease.
    The Journal of pathology, 2007, Volume: 212, Issue:1

    Topics: Aldosterone; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Diseases; Coronavirus; Female;

2007
A primer on aldosterone for gynecologists/obstetricians.
    The Journal of reproductive medicine, 2007, Volume: 52, Issue:2 Suppl

    Topics: Aldosterone; Female; Gynecology; Heart Failure; Humans; Hypertension; Mineralocorticoid Receptor Ant

2007
Drug insight: aldosterone-receptor antagonists in heart failure--the journey continues.
    Nature clinical practice. Cardiovascular medicine, 2007, Volume: 4, Issue:7

    Topics: Aldosterone; Contraindications; Drug Therapy, Combination; Eplerenone; Heart Failure; Humans; Hypert

2007
The role of aldosterone and mineralocorticoid receptors in cardiovascular disease.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2007, Volume: 7, Issue:3

    Topics: Aldosterone; Animals; Atherosclerosis; Cardiovascular Diseases; Heart Failure; Humans; Hyperaldoster

2007
[Hypertension in postmenopausal women --selected pathomechanisms].
    Przeglad lekarski, 2006, Volume: 63, Issue:12

    Topics: Age Factors; Aldosterone; Angiotensin II; Blood Pressure; Body Mass Index; Dyslipidemias; Estrogen R

2006
Aldosteronism and hypertension.
    Clinical journal of the American Society of Nephrology : CJASN, 2006, Volume: 1, Issue:5

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Mass

2006
The association of aldosterone with obesity-related hypertension and the metabolic syndrome.
    Seminars in nephrology, 2007, Volume: 27, Issue:5

    Topics: Adipose Tissue; Aldosterone; Animals; Blood Pressure; Humans; Hypertension; Metabolic Syndrome; Obes

2007
Adrenal causes of hypertension: pheochromocytoma and primary aldosteronism.
    Reviews in endocrine & metabolic disorders, 2007, Volume: 8, Issue:4

    Topics: Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Models, Biological; Pheochrom

2007
[Hypertension and metabolic syndrome].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Sep-10, Volume: 96, Issue:9

    Topics: Aldosterone; Humans; Hypertension; Insulin Resistance; Metabolic Syndrome; Oxidative Stress; Renin-A

2007
Hyperaldosteronism: a commonly occurring underlying feature of essential hypertension and the metabolic syndrome?
    Current opinion in endocrinology, diabetes, and obesity, 2007, Volume: 14, Issue:3

    Topics: Aldosterone; Black or African American; Humans; Hyperaldosteronism; Hypertension; Insulin Resistance

2007
Aldosterone and refractory hypertension.
    Current opinion in endocrinology, diabetes, and obesity, 2007, Volume: 14, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Drug Resistance; Humans; Hyperaldosteronism; H

2007
Aldosterone and progression of renal disease.
    Current opinion in nephrology and hypertension, 2008, Volume: 17, Issue:1

    Topics: Aldosterone; Animals; Disease Progression; Humans; Hypertension; Kidney Diseases; Prorenin Receptor;

2008
Resistant hypertension and aldosteronism.
    Current hypertension reports, 2007, Volume: 9, Issue:5

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Bloc

2007
Rapid non-genomic effects of aldosterone on the renal vasculature.
    Steroids, 2008, Volume: 73, Issue:9-10

    Topics: Aldosterone; Animals; Blood Flow Velocity; Disease Progression; Endothelium, Vascular; Glomerular Fi

2008
Endocrine arterial hypertension: diagnostic approach in clinical practice.
    Minerva endocrinologica, 2008, Volume: 33, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Algorithms; Catecholamines; Cushing Syndrome; Diagnos

2008
Primary aldosteronism, a major form of low renin hypertension: from screening to diagnosis.
    Trends in endocrinology and metabolism: TEM, 2008, Volume: 19, Issue:3

    Topics: Aldosterone; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Re

2008
Aldosterone and glomerular podocyte injury.
    Clinical and experimental nephrology, 2008, Volume: 12, Issue:4

    Topics: Aldosterone; Animals; Disease Models, Animal; Humans; Hypertension; Metabolic Syndrome; Oxidative St

2008
Aldosterone and metabolic syndrome: is increased aldosterone in metabolic syndrome patients an additional risk factor?
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:5

    Topics: Aldosterone; Cardiovascular Diseases; Humans; Hypertension; Lipid Metabolism; Metabolic Syndrome; Ob

2008
Spotlight on HDL-raising therapies: insights from the torcetrapib trials.
    Nature clinical practice. Cardiovascular medicine, 2008, Volume: 5, Issue:6

    Topics: Aldosterone; Anticholesteremic Agents; Blood Pressure; Cardiovascular Diseases; Cholesterol Ester Tr

2008
Aldosterone in salt-sensitive hypertension and metabolic syndrome.
    Journal of molecular medicine (Berlin, Germany), 2008, Volume: 86, Issue:6

    Topics: Aldosterone; Animals; Humans; Hypertension; Metabolic Syndrome; Receptors, Mineralocorticoid; Renin-

2008
The role of adrenal steroidogenesis in arterial hypertension.
    Endocrine development, 2008, Volume: 13

    Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertensi

2008
[Diagnostic tests for endocrine hypertension].
    Rinsho byori. The Japanese journal of clinical pathology, 1984, Volume: Spec No 58

    Topics: Adrenal Cortex Function Tests; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; A

1984
Disorders of the adrenal cortex: their effects on electrolyte metabolism.
    Clinics in endocrinology and metabolism, 1984, Volume: 13, Issue:2

    Topics: Addison Disease; Adrenal Cortex Diseases; Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital;

1984
An overview of the clinical pharmacology of enalapril.
    British journal of clinical pharmacology, 1984, Volume: 18 Suppl 2

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Di

1984
Some aspects of kidney function, the renin-aldosterone system and sympathetic activity in essential hypertension.
    Acta medica Scandinavica. Supplementum, 1980, Volume: 636

    Topics: Adrenergic beta-Antagonists; Adult; Albuminuria; Aldosterone; Catecholamines; Female; Glomerular Fil

1980
Antihypertensive beta-blockade and the renin-angiotensin system.
    Cardiology, 1980, Volume: 66 Suppl 1

    Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensins; Animals; Hypertension; Potassium; Renin

1980
Renin-angiotensin-aldosterone and hypertension.
    Endocrine reviews, 1980,Winter, Volume: 1, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensinogen; Angiotensins; Animals; Blood Press

1980
Measurement of the hormones of the renin system in hypertensive patients.
    Clinical biochemistry, 1981, Volume: 14, Issue:5

    Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Blood Volume;

1981
Renin in essential hypertension.
    Clinics in endocrinology and metabolism, 1981, Volume: 10, Issue:3

    Topics: Adrenergic beta-Antagonists; Age Factors; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme

1981
The effect of adrenergic blockade on potassium concentrations in different conditions.
    Acta medica Scandinavica. Supplementum, 1983, Volume: 672

    Topics: Adrenergic beta-Antagonists; Aldosterone; Animals; Epinephrine; Humans; Hypertension; Pindolol; Pota

1983
Adrenergic regulation of renin release and effects on angiotensin and aldosterone.
    Acta medica Scandinavica. Supplementum, 1983, Volume: 672

    Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Animals; Dinoprostone; Dogs; Electric Stim

1983
Hypertension, the adrenal and the kidney: lessons from pharmacologic interruption of the renin-angiotensin system.
    Advances in internal medicine, 1980, Volume: 25

    Topics: Adrenal Glands; Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Angiotensins; Animals; Blo

1980
Clonidine and the kidney.
    Journal of cardiovascular pharmacology, 1980, Volume: 2 Suppl 1

    Topics: Adrenal Gland Neoplasms; Aldosterone; Antihypertensive Agents; Catecholamines; Clonidine; Humans; Hy

1980
[The renin-angiotensin system. Physiopathological aspects and clinical implications of hypertensive syndromes. A survey].
    Minerva medica, 1981, Mar-31, Volume: 72, Issue:12

    Topics: Acromegaly; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Cushing Syndrome; Glycoproteins;

1981
Exogenous mineralocorticoid-like disorders.
    Clinics in endocrinology and metabolism, 1981, Volume: 10, Issue:3

    Topics: Adult; Aldosterone; Animals; Carbenoxolone; Emollients; Female; Fludrocortisone; Fluprednisolone; Gl

1981
Captopril in the treatment of hypertension.
    Acta clinica Belgica, 1982, Volume: 37, Issue:3

    Topics: Aldosterone; Captopril; Drug Eruptions; Hemodynamics; Humans; Hypertension; Hypotension; Physical Ex

1982
Quo vadis basic and clinical chronobiology: promise for health maintenance.
    The American journal of anatomy, 1983, Volume: 168, Issue:4

    Topics: Adrenal Cortex; Alcoholism; Aldosterone; Biological Clocks; Blood Pressure; Breast Neoplasms; Cardio

1983
The renin system and future trends in management of high blood pressure.
    Clinical and experimental hypertension, 1980, Volume: 2, Issue:3-4

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Antihypertensive Agents; Blood

1980
Hypertension of childhood with suppressed renin.
    Endocrine reviews, 1980,Fall, Volume: 1, Issue:4

    Topics: 18-Hydroxydesoxycorticosterone; 20-alpha-Dihydroprogesterone; Adolescent; Adrenal Cortex; Adrenal Hy

1980
[Pharmacological effects of captopril].
    La Nouvelle presse medicale, 1981, Apr-30, Volume: 10, Issue:19

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Bradyk

1981
Angiotensin converting enzyme (ACE) inhibitors.
    Annual review of pharmacology and toxicology, 1982, Volume: 22

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Capt

1982
Enzymatic disorders and hypertension.
    Clinics in endocrinology and metabolism, 1981, Volume: 10, Issue:3

    Topics: Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; A

1981
The kinins and prostaglandins in hypertension.
    Clinics in endocrinology and metabolism, 1981, Volume: 10, Issue:3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Water; Dinoprost; Female; Furos

1981
[Renin-angiotensin-aldosterone function tests].
    Nihon rinsho. Japanese journal of clinical medicine, 1982, Volume: 40, Issue:9

    Topics: Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Desoxycorti

1982
Angiotensin-converting enzyme and its clinical significance--a review.
    Journal of clinical pathology, 1983, Volume: 36, Issue:8

    Topics: Adolescent; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dogs;

1983
Overview: the role of angiotensin-converting enzyme inhibitors in cardiovascular therapy.
    Federation proceedings, 1984, Volume: 43, Issue:5

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dipeptides; Diuretics; Dose-Respon

1984
[Hypertensinogenic steroids].
    Nihon rinsho. Japanese journal of clinical medicine, 1984, Volume: 42, Issue:11

    Topics: Aldosterone; Animals; Blood Pressure; Calcium; Catecholamines; Desoxycorticosterone; Female; Glucoco

1984
[New mineralocorticoids and mineralocorticoid-like steroids].
    Nihon rinsho. Japanese journal of clinical medicine, 1984, Volume: 42, Issue:11

    Topics: Aldosterone; Androstenedione; Animals; Desoxycorticosterone; Female; Humans; Hypertension; Pregnancy

1984
Interaction between the natriuretic effects of renal perfusion pressure and the antinatriuretic effects of angiotensin and aldosterone in control of sodium excretion.
    Journal de physiologie, 1984, Volume: 79, Issue:6

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Volume; Hypertension; Inf

1984
The Franz Gross Memorial Lecture. The renin-aldosterone connection: past, present and future.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Animals; Diet, Sodium-Restricted; Dogs; Humans; Hyper

1984
Pathophysiology of hypertension and ischemic heart disease.
    International anesthesiology clinics, 1980,Winter, Volume: 18, Issue:4

    Topics: Adult; Aldosterone; Animals; Cardiomegaly; Coronary Circulation; Coronary Disease; Endocardium; Hear

1980
[The catecholamine system].
    Nihon rinsho. Japanese journal of clinical medicine, 1982, Volume: 40, Issue:9

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Catecholamines; Dogs; Drug Interactions; Human

1982
Toward chronobiologic pattern discrimination of the risk of developing breast cancer and other diseases.
    Revista espanola de oncologia, 1982, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aldosterone; Breast Neoplasms; Carbohydrate Metabolism; Circadian Rh

1982
Pathophysiology of the syndrome of hyporeninemic hypoaldosteronism.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:2

    Topics: Acidosis; Aged; Aldosterone; Ammonia; Angiotensin II; Bicarbonates; Cations, Monovalent; Extracellul

1980
The renal kallikrein-kinin system.
    The American journal of physiology, 1980, Volume: 238, Issue:4

    Topics: Acute Kidney Injury; Aldosterone; Angiotensins; Animals; Blood Pressure; Glomerular Filtration Rate;

1980
Steroid receptors and hypertension.
    Circulation research, 1980, Volume: 46, Issue:6 Pt 2

    Topics: Aldosterone; Animals; Blood Pressure; Cardiac Output; Cytosol; Dexamethasone; Drinking; Fludrocortis

1980
Salt balance and long-term blood pressure control.
    Annual review of medicine, 1980, Volume: 31

    Topics: Aldosterone; Blood Pressure; Blood Volume; Cardiac Output; Diet; Extracellular Space; Humans; Hypert

1980
[Effect of oral contraceptives on the circulatory system].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, May-12, Volume: 35, Issue:19

    Topics: Aldosterone; Angiotensin II; Cardiovascular Diseases; Cerebrovascular Disorders; Contraceptives, Ora

1980
Sodium and hypertension. A review of the role of sodium in pathogenesis and the action of diuretic drugs.
    Pharmacology & therapeutics, 1980, Volume: 9, Issue:3

    Topics: Age Factors; Aldosterone; Amiloride; Benzothiadiazines; Diuretics; Furosemide; Humans; Hypertension;

1980
Effects of captopril in animal models of hypertension.
    Clinical and experimental hypertension, 1980, Volume: 2, Issue:3-4

    Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Animals; Arteries; Blood Pressure; Brady

1980
Primary aldosteronism--a review.
    Urological survey, 1980, Volume: 30, Issue:4

    Topics: 18-Hydroxycorticosterone; Adenoma; Adolescent; Adrenal Glands; Adult; Aldosterone; Child; Humans; Hy

1980
Hypertension in pregnancy.
    Contributions to nephrology, 1980, Volume: 23

    Topics: Aldosterone; Angiotensins; Female; Humans; Hypertension; Kidney; Pre-Eclampsia; Pregnancy; Pregnancy

1980
Sodium and mineralocorticoids in normal pregnancy.
    Kidney international, 1980, Volume: 18, Issue:2

    Topics: Aldosterone; Angiotensinogen; Desoxycorticosterone; Diet, Sodium-Restricted; Diuretics; Female; Huma

1980
Regulation of aldosterone secretion in normotensive and hypertensive man.
    Pathobiology annual, 1980, Volume: 10

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Humans; Hypertension; Potassiu

1980
Captopril: a preliminary review of its pharmacological properties and therapeutic efficacy.
    Drugs, 1980, Volume: 20, Issue:6

    Topics: Aldosterone; Angiotensin II; Captopril; Drug Interactions; Heart Failure; Hemodynamics; Humans; Hype

1980
The renin-angiotensin system and aldosterone in hypertension: a brief review of some aspects.
    International journal of obesity, 1981, Volume: 5 suppl 1

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Renin

1981
The role of the renin-angiotensin-aldosterone system in circulatory control and hypertension.
    British journal of anaesthesia, 1981, Volume: 53, Issue:7

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin

1981
[Essential hypertension, renovascular hypertension and potassium metabolism].
    Nihon rinsho. Japanese journal of clinical medicine, 1981, Volume: 39, Issue:2

    Topics: Aldosterone; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Potassium; Renin

1981
[Primary hyperaldosteronism-current theories].
    Kardiologia polska, 1981, Volume: 24, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia

1981
[Limited usefulness of corticosteroid therapy (author's transl)].
    Ryumachi. [Rheumatism], 1981, Volume: 21, Issue:1

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Arthritis, Rheumatoid; Glucose; Humans; Hypert

1981
Studies on the mechanism of mineralocorticoid-induced hypertension: evidence for the presence of an in-situ mechanism in the arterial wall for a direct action of mineralocorticoids.
    Clinical biochemistry, 1981, Volume: 14, Issue:5

    Topics: Aldosterone; Animals; Arteries; Cell Nucleus; Chromatin; Corticosterone; Cytosol; Desoxycorticostero

1981
Interactions of renal prostaglandins with the renin-angiotensin system.
    Pharmacology & therapeutics, 1981, Volume: 15, Issue:2

    Topics: Aldosterone; Animals; Arachidonic Acids; Dogs; Humans; Hypertension; Kidney; Pressoreceptors; Prosta

1981
Pathogenesis of mineralocorticoid hypertension.
    Clinics in endocrinology and metabolism, 1981, Volume: 10, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Animals; Bloo

1981
[Recent medico-social aspects of arterial hypertension].
    Minerva medica, 1982, Jul-14, Volume: 73, Issue:28-29

    Topics: Adult; Age Factors; Aged; Aldosterone; Autonomic Nervous System; Blood Pressure Determination; Brady

1982
Renin-angiotensin-aldosterone system for blood pressure and electrolyte homeostasis and its involvement in hypertension, in congestive heart failure and in associated cardiovascular damage (myocardial infarction and stroke).
    Journal of human hypertension, 1995, Volume: 9, Issue:6

    Topics: Aldosterone; Animals; Blood Pressure; Cardiovascular Diseases; Cerebrovascular Disorders; Electrolyt

1995
The cardiac renin-angiotensin-aldosterone system and hypertensive cardiac hypertrophy.
    The American journal of cardiology, 1995, Nov-02, Volume: 76, Issue:13

    Topics: Adaptation, Physiological; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; An

1995
[New data on mineralocorticoid hormones. Physiopathological implications].
    Presse medicale (Paris, France : 1983), 1995, Sep-23, Volume: 24, Issue:27

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Receptors, Glucocorticoid; Receptors, Mineral

1995
The promiscuous receptor: a case for the guardian enzyme.
    Cardiovascular research, 1995, Volume: 30, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Corticosterone; Humans; Hydroxysteroid

1995
Mineralocorticoid receptors and hypertension.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 53, Issue:1-6

    Topics: Aldosterone; Animals; Epithelium; Heart Diseases; Hypertension; Rats; Receptors, Glucocorticoid; Rec

1995
Pharmacological modulation of cardiac fibroblast function.
    Herz, 1995, Volume: 20, Issue:2

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomyopathy, Dilated; Collagen; E

1995
Renal parenchymal disease and hypertension.
    Seminars in nephrology, 1995, Volume: 15, Issue:2

    Topics: Aldosterone; Animals; Blood Proteins; Cardenolides; Digoxin; Endothelins; Humans; Hypertension; Kall

1995
Significance of 19-noraldosterone, a new mineralocorticoid, in clinical and experimental hypertension.
    Steroids, 1995, Volume: 60, Issue:1

    Topics: Aldosterone; Animals; Humans; Hypertension; Rats; Rats, Inbred SHR

1995
Aldosterone-secreting adrenal cortical adenoma in an 11-year-old child and collective review of the literature.
    European journal of pediatrics, 1994, Volume: 153, Issue:10

    Topics: Adrenocortical Adenoma; Aldosterone; Alkalosis; Child; Female; Humans; Hyperaldosteronism; Hypertens

1994
Recent advances in endothelin research on cardiovascular and endocrine systems.
    Endocrine journal, 1994, Volume: 41, Issue:5

    Topics: Adrenal Glands; Aldosterone; Animals; Cardiovascular Physiological Phenomena; Endothelins; Hemodynam

1994
Type II pseudohypoaldosteronism. Report of a case and review of the literature.
    Journal of endocrinological investigation, 1994, Volume: 17, Issue:6

    Topics: Aldosterone; Atrial Natriuretic Factor; Female; Humans; Hyperkalemia; Hypertension; Middle Aged; Pot

1994
Developments in the molecular biology of corticosteroid synthesis and action: implications for an understanding of essential hypertension.
    Journal of hypertension, 1994, Volume: 12, Issue:5

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Aldosterone; Animals; Cortisone; Hum

1994
Apparent mineralocorticoid excess.
    Journal of human hypertension, 1994, Volume: 8, Issue:5

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Glycyrrhiza; Humans; Hydroxysteroid Dehydrogenas

1994
Control of vascular reactivity in pregnancy: the basis for therapeutic approaches to prevent pregnancy-induced hypertension.
    Seminars in perinatology, 1994, Volume: 18, Issue:2

    Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Metabolic Clearance Rate; Pregnancy; Preg

1994
Glucocorticoid-remediable aldosteronism.
    Endocrinology and metabolism clinics of North America, 1994, Volume: 23, Issue:2

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mutation

1994
[The dopaminergic regulation of the renin-angiotensin-aldosterone system. The control of aldosterone secretion (2)].
    Likars'ka sprava, 1994, Issue:2

    Topics: Aldosterone; Animals; Dopamine; Humans; Hypertension; Receptors, Dopamine; Renin-Angiotensin System

1994
Calcium antagonism: aldosterone and vascular responses to catecholamines and angiotensin II in man.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:6

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Cardiovascular Physiological

1993
The association of aldosterone-producing adrenal adenoma in a patient with autosomal dominant polycystic kidney disease.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1994, Volume: 23, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hyper

1994
[Age-related changes in the renin-angiotensin-aldosterone system and the sympathetic nervous system in patients with essential hypertension].
    Minerva cardioangiologica, 1993, Volume: 41, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Blood Pressure; Catecholamines; Fema

1993
AANA Journal course. 5: Update for nurse anesthetists--essential hypertension, anesthesia, and the kidney.
    AANA journal, 1993, Volume: 61, Issue:6

    Topics: Aldosterone; Anesthesia; Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Intraoperative

1993
Fatty acids may regulate aldosterone secretion and mediate some of insulin's effects on blood pressure.
    Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 48, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Black People; Blood Pressure; Cattle; Cohort Studies; Dogs; Fa

1993
Reduced aldosterone metabolites in hypertension.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 45, Issue:1-3

    Topics: Aldosterone; Animals; Female; Hypertension; Male; Mineralocorticoids; Sodium, Dietary

1993
Conn syndrome in a child, caused by adrenal adenoma.
    Journal of pediatric surgery, 1996, Volume: 31, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Child; Fatigue; Female; Humans; Hyperaldosteronism; H

1996
Mineralocorticoids, salt, hypertension: effects on the heart.
    Steroids, 1996, Volume: 61, Issue:4

    Topics: Aldosterone; Animals; Cardiomegaly; Fibrosis; Heart; Humans; Hypertension; Hypokalemia; Mineralocort

1996
Aldosterone and its mechanism of action: more questions than answers.
    Australian and New Zealand journal of medicine, 1995, Volume: 25, Issue:6

    Topics: Aldosterone; Animals; Blood Pressure; Humans; Hydrocortisone; Hypertension; Receptors, Mineralocorti

1995
11 beta-Hydroxysteroid dehydrogenase deficit: a rare cause of arterial Hypertension. Diagnosis and therapeutic approach in two young brothers.
    European journal of endocrinology, 1996, Volume: 135, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Child; Child, Preschool; Cortisone; Dexamethason

1996
Inherited forms of mineralocorticoid hypertension.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 28, Issue:6

    Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Animals; Humans; Hydrocortisone; Hypertension; Mineral

1996
The renin-angiotensin-aldosterone system and the cardiac natriuretic peptides.
    Heart (British Cardiac Society), 1996, Volume: 76, Issue:3 Suppl 3

    Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiac Output, Low; Central Nervou

1996
Clinical relevance of about-yearly changes in blood pressure and the environment.
    International journal of biometeorology, 1996, Volume: 39, Issue:4

    Topics: Aldosterone; Blood Pressure; Chronobiology Phenomena; Humans; Hypertension; Melatonin; Models, Cardi

1996
11 beta-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess.
    Endocrine reviews, 1997, Volume: 18, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; ACTH Syndrome, Ectopic; Aldosterone; Glycyrrhiza; Humans; Hyd

1997
Mineralocorticoid receptors and glucocorticoid receptors.
    Clinical endocrinology, 1996, Volume: 45, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Corticosterone; Humans; Hydrocortisone;

1996
Vascular function in OSA.
    Sleep, 1996, Volume: 19, Issue:10 Suppl

    Topics: Aldosterone; Angiotensin II; Arginine; Atrial Natriuretic Factor; Endothelium; Humans; Hypertension;

1996
[Pathophysiology of left ventricular hypertrophy in arterial hypertension].
    Praxis, 1997, Feb-11, Volume: 86, Issue:7

    Topics: Aldosterone; Cyclic AMP; Growth Substances; Heart; Humans; Hypertension; Hypertrophy, Left Ventricul

1997
[Mineralocorticoid-induced hypertension].
    Medizinische Klinik (Munich, Germany : 1983), 1997, May-15, Volume: 92, Issue:5

    Topics: 17-Hydroxysteroid Dehydrogenases; Adenoma; Aldosterone; Chromosomes, Human, Pair 8; Crossing Over, G

1997
Nonesterified fatty acids in the pathogenesis of hypertension: theory and evidence.
    Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 57, Issue:1

    Topics: Aldosterone; Animals; Blood Pressure; Fatty Acids, Nonesterified; Homeostasis; Humans; Hypertension;

1997
Hypertension in autosomal dominant polycystic kidney disease.
    Kidney international. Supplement, 1997, Volume: 61

    Topics: Aldosterone; Humans; Hypertension; Polycystic Kidney, Autosomal Dominant; Renal Circulation; Renin-A

1997
Regulation and role of myocardial collagen matrix remodeling in hypertensive heart disease.
    Advances in experimental medicine and biology, 1997, Volume: 432

    Topics: Adult; Aldosterone; Angiotensin II; Animals; Cells, Cultured; Collagen; Collagenases; Heart; Heart D

1997
Left ventricular anatomy and function in primary aldosteronism and renovascular hypertension.
    Advances in experimental medicine and biology, 1997, Volume: 432

    Topics: Adrenalectomy; Aldosterone; Animals; Heart; Heart Ventricles; Humans; Hyperaldosteronism; Hypertensi

1997
Left ventricular hypertrophy in hypertension: etiology, treatment, and controversies.
    The Mount Sinai journal of medicine, New York, 1998, Volume: 65, Issue:2

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Hem

1998
Effects of sodium restriction on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglyceride: a meta-analysis.
    JAMA, 1998, May-06, Volume: 279, Issue:17

    Topics: Aldosterone; Blood Pressure; Body Weight; Catecholamines; Cholesterol; Diet, Sodium-Restricted; Horm

1998
[Mineralocorticoids and hypertension].
    Cardiologia (Rome, Italy), 1998, Volume: 43, Issue:3

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Animals; Child; Child, Pres

1998
Liddle's syndrome in an elderly woman.
    Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:4

    Topics: Aged; Aldosterone; Alkalosis; Diagnosis, Differential; Diuretics; Female; Humans; Hypernatremia; Hyp

1998
Renin-producing adrenal tumor: report of a case.
    Surgery today, 1998, Volume: 28, Issue:9

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Humans; Hypertension; Ma

1998
[The role of neurohormonal mechanisms in the etiopathogenesis of essential hypertension].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1998, Volume: 5, Issue:27

    Topics: Aldosterone; Angiotensin II; Endothelins; Humans; Hypertension; Neuropeptide Y; Nitric Oxide; Renin;

1998
[The effect of reduced sodium intake on blood pressure, body weight, renin, aldosterone, catecholamines, cholesterol and triglycerides. A meta-analysis].
    Ugeskrift for laeger, 1999, Apr-26, Volume: 161, Issue:17

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Catecholamines; Cholesterol; Diet, Sodium-Res

1999
[Molecular structure of renin-angiotensin-aldosterone system].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1999, Volume: 6, Issue:34

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Electrolytes; Gene Expression

1999
[Hypertension and mineralocorticoids. Usefulness of renin and aldosterone measurements].
    Revista medica de Chile, 1999, Volume: 127, Issue:5

    Topics: Aldosterone; Electrolytes; Humans; Hyperaldosteronism; Hypertension; Hypoaldosteronism; Mineralocort

1999
Interactions between endothelin-1 and the renin-angiotensin-aldosterone system.
    Cardiovascular research, 1999, Aug-01, Volume: 43, Issue:2

    Topics: Aldosterone; Animals; Endothelin-1; Humans; Hypertension; Models, Biological; Plasma Volume; Recepto

1999
Aldosterone and the heart: towards a physiological function?
    Cardiovascular research, 1999, Volume: 43, Issue:1

    Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Animals; Cytochrome P-450 CYP11B2; Fibrosis; Gene Expre

1999
Steroid dehydrogenase structures, mechanism of action, and disease.
    Vitamins and hormones, 2000, Volume: 58

    Topics: 17-Hydroxysteroid Dehydrogenases; Aldosterone; Amino Acid Sequence; Animals; Cortisone Reductase; Gl

2000
Beneficial interactions between pharmacological, pathophysiological and hypertension research.
    Journal of hypertension, 1999, Volume: 17, Issue:12 Pt 2

    Topics: Aldosterone; Animals; Antihypertensive Agents; Calcium; Humans; Hypertension; Renin-Angiotensin Syst

1999
Mineralocorticoid selectivity: molecular and cellular aspects.
    Kidney international, 2000, Volume: 57, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Blood Pressure; Glucocorticoids; Humans

2000
Role of the 11beta-hydroxysteroid dehydrogenase type 2 in blood pressure regulation.
    Kidney international, 2000, Volume: 57, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Blood Pressure; Humans; Hydroxysteroid Dehydroge

2000
Aldosterone antagonists in hypertension and heart failure.
    Annales d'endocrinologie, 2000, Volume: 61, Issue:1

    Topics: Aldosterone; Animals; Female; Heart Failure; Humans; Hypertension; Male; Mineralocorticoid Receptor

2000
Clinical implications of the ovarian/endometrial renin-angiotensin-aldosterone system.
    Annals of the New York Academy of Sciences, 2000, Volume: 900

    Topics: Aldosterone; Animals; Endometrium; Female; Humans; Hypertension; Male; Menstrual Cycle; Ovary; Pre-E

2000
Heart-hitting tales of salt and destruction.
    The Journal of laboratory and clinical medicine, 2000, Volume: 136, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cardiovascular Diseases; Humans; Hyperaldosteronism;

2000
Angiotensin II receptor blockers: equal or preferred substitutes for ACE inhibitors?
    Archives of internal medicine, 2000, Jul-10, Volume: 160, Issue:13

    Topics: Acrylates; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors;

2000
Dynamic interactions between integrative physiology and molecular medicine: the key to understand the mechanism of action of aldosterone in the kidney.
    Canadian journal of physiology and pharmacology, 2000, Volume: 78, Issue:8

    Topics: Acid-Base Equilibrium; Aldosterone; Animals; Bicarbonates; Humans; Hypertension; Kidney; Sodium Chlo

2000
Aldosterone-related genetic effects in hypertension.
    Current hypertension reports, 2000, Volume: 2, Issue:3

    Topics: Aldosterone; Cytochrome P-450 CYP11B2; Epithelium; Humans; Hyperaldosteronism; Hypertension; Ion Tra

2000
Aldosterone and vascular damage.
    Current hypertension reports, 2000, Volume: 2, Issue:3

    Topics: Adrenal Cortex; Aldosterone; Arteries; Autonomic Nervous System; Baroreflex; Body Water; Compliance;

2000
The promise of selective aldosterone receptor antagonists for the treatment of hypertension and congestive heart failure.
    Current hypertension reports, 2000, Volume: 2, Issue:4

    Topics: Aldosterone; Animals; Antihypertensive Agents; Eplerenone; Heart Failure; Humans; Hypertension; Mine

2000
[Steroid hormone].
    Nihon rinsho. Japanese journal of clinical medicine, 2000, Volume: 58 Suppl 1

    Topics: Aldosterone; Animals; Humans; Hydroxysteroid Dehydrogenases; Hypertension; Mineralocorticoids

2000
Genetic determination of human essential hypertension.
    The Tohoku journal of experimental medicine, 2000, Volume: 192, Issue:1

    Topics: Aldosterone; Carrier Proteins; Humans; Hydrocortisone; Hypertension; Kallikreins; Kidney; Kinins; Re

2000
Non-genomic actions of aldosterone: role in hypertension.
    Current opinion in nephrology and hypertension, 2001, Volume: 10, Issue:2

    Topics: Aldosterone; Animals; Blood Pressure; Calcium; Cyclic AMP; Humans; Hypertension; Inositol 1,4,5-Tris

2001
K(+) depletion and the progression of hypertensive disease or heart failure. The pathogenic role of diuretic-induced aldosterone secretion.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2

    Topics: Aldosterone; Animals; Antihypertensive Agents; Benzothiadiazines; Clinical Trials as Topic; Disease

2001
Molecular mechanisms of human hypertension.
    Cell, 2001, Feb-23, Volume: 104, Issue:4

    Topics: Aldosterone; Animals; Female; Genes, Recessive; Humans; Hypertension; Male; Mineralocorticoids; Mode

2001
Aldosterone as a mediator of progressive renal disease: pathogenetic and clinical implications.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 37, Issue:4

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Eplerenone; Humans; Hyper

2001
A review of the medical treatment of primary aldosteronism.
    Journal of hypertension, 2001, Volume: 19, Issue:3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Humans; Hyperaldost

2001
Primary aldosteronism: revival of a syndrome.
    Journal of hypertension, 2001, Volume: 19, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mutation; Renin; Syndrome

2001
The spironolactone renaissance.
    Expert opinion on investigational drugs, 2001, Volume: 10, Issue:5

    Topics: Aldosterone; Androgen Antagonists; Angiogenesis Inhibitors; Animals; Clinical Trials as Topic; Colla

2001
The hypertensive patient with hypokalaemia: the search for hyperaldosteronism.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:6

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Magnetic Resonance Angiography;

2001
Aldosterone and the hypertensive kidney: its emerging role as a mediator of progressive renal dysfunction: a paradigm shift.
    Journal of hypertension, 2001, Volume: 19, Issue:5

    Topics: Aldosterone; Animals; Disease Progression; Humans; Hypertension; Kidney; Kidney Diseases; Renal Insu

2001
Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure.
    Cardiology clinics, 2001, Volume: 19, Issue:2

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit

2001
Pathophysiological effects of aldosterone in cardiovascular tissues.
    Trends in endocrinology and metabolism: TEM, 2001, Volume: 12, Issue:7

    Topics: Adrenalectomy; Aldosterone; Animals; Cardiovascular Diseases; Cerebral Hemorrhage; Humans; Hypertens

2001
The diagnosis of essential and secondary hypertension in adults.
    The Journal of family practice, 2001, Volume: 50, Issue:8

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Algorithms; Angiography; Blood Pressure Determination;

2001
Hyperaldosteronism: recent concepts, diagnosis, and management.
    Postgraduate medical journal, 2001, Volume: 77, Issue:912

    Topics: Aged; Aldosterone; Diuretics; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; M

2001
Primary aldosteronism: are we diagnosing and operating on too few patients?
    World journal of surgery, 2001, Volume: 25, Issue:7

    Topics: Aldosterone; Diagnostic Techniques, Endocrine; Endocrine Surgical Procedures; Humans; Hyperaldostero

2001
Recent studies with eplerenone, a novel selective aldosterone receptor antagonist.
    Current opinion in pharmacology, 2001, Volume: 1, Issue:2

    Topics: Aldosterone; Animals; Cardiovascular System; Clinical Trials as Topic; Endothelium, Vascular; Eplere

2001
[Primary hyperaldosteronism].
    La Revue du praticien, 1998, Apr-01, Volume: 48, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Algorithms; Amiloride; Di

1998
Genetics of the mineralocorticoid system in primary hypertension.
    Current hypertension reports, 2002, Volume: 4, Issue:1

    Topics: Adrenal Glands; Aldosterone; Cytochrome P-450 CYP11B2; Humans; Hydrocortisone; Hydroxysteroid Dehydr

2002
The neurohormonal natural history of essential hypertension: towards primary or tertiary aldosteronism?
    Journal of hypertension, 2002, Volume: 20, Issue:1

    Topics: Aldosterone; Cytochrome P-450 CYP11B2; Disease Progression; Humans; Hyperaldosteronism; Hypertension

2002
Epithelial sodium channel and the control of sodium balance: interaction between genetic and environmental factors.
    Annual review of physiology, 2002, Volume: 64

    Topics: Aldosterone; Animals; Epithelial Sodium Channels; Extravascular Lung Water; Humans; Hypertension; So

2002
Gene therapy for hypertension and restenosis.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2000, Volume: 1, Issue:3

    Topics: Aldosterone; Animals; Coronary Restenosis; Genetic Therapy; Humans; Hypertension; Renin-Angiotensin

2000
Is aldosterone the missing link in refractory hypertension?: aldosterone-to-renin ratio as a marker of inappropriate aldosterone activity.
    Journal of human hypertension, 2002, Volume: 16, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Biomarkers; Humans; Hyperaldosteronism; Hypertension; Prevalen

2002
Primary aldosteronism, a common entity? the myth persists.
    Journal of human hypertension, 2002, Volume: 16, Issue:3

    Topics: Aldosterone; Biomarkers; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin

2002
Familial varieties of primary aldosteronism.
    Clinical and experimental pharmacology & physiology, 2001, Volume: 28, Issue:12

    Topics: Adrenocortical Adenoma; Aldosterone; Chromosome Mapping; Chromosomes, Human, Pair 7; Genetic Variati

2001
Pathophysiology of propranolol in hypertension.
    Southern medical journal, 1977, Volume: 70, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Diu

1977
Acute and long-term studies of the mechanisms of action of beta-blocking drugs in lowering blood pressure.
    The American journal of medicine, 1976, May-31, Volume: 60, Issue:6

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Circadian Rhy

1976
Clinical pharmacology of antihypertensive drugs.
    The Medical clinics of North America, 1977, Volume: 61, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Bethanidine; Blo

1977
[Incidence of beta-blockers on plasma renin activity. Present status].
    La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31

    Topics: Acebutolol; Adrenergic beta-Antagonists; Aldosterone; Blood Pressure; Depression, Chemical; Dose-Res

1978
The renin system in essential, renovascular and adrenocortical hypertension: an overview.
    Advances in nephrology from the Necker Hospital, 1977, Volume: 7

    Topics: Aldosterone; Blood Volume; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant

1977
[Mineralocorticoid excess in essential hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1979, Volume: 37, Issue:10

    Topics: 18-Hydroxydesoxycorticosterone; Aldosterone; Animals; Dehydroepiandrosterone; Humans; Hydroxycortico

1979
Abnormal regulation of aldosterone in hypertension.
    Advances in internal medicine, 1975, Volume: 20

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Circadian Rhythm; Diures

1975
The renin-angiotensin-aldosterone system in parenchymal kidney disease.
    Advances in nephrology from the Necker Hospital, 1975, Volume: 5

    Topics: Acute Kidney Injury; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Blood

1975
Mineralocorticoid hormones.
    Advances in steroid biochemistry and pharmacology, 1976, Volume: 5

    Topics: Acid-Base Imbalance; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Anima

1976
The adrenal cortex and essential hypertension.
    Recent progress in hormone research, 1976, Volume: 32

    Topics: Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Ani

1976
Converting enzyme inhibition and blood pressure regulation.
    Agents and actions, 1976, Volume: 6, Issue:4

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Dogs

1976
Drug-induced hypertension: pathogenesis and management.
    Drugs, 1976, Volume: 12, Issue:3

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Antidepressive Agents, Tricyclic; Carbenox

1976
Experimental and clinical studies with converting enzyme inhibitor.
    Progress in biochemical pharmacology, 1976, Volume: 12

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressur

1976
The biochemistry of the renin-angiotensin system and its role in hypertension.
    The American journal of medicine, 1976, May-31, Volume: 60, Issue:6

    Topics: Aldosterone; Angiotensin II; Angiotensin III; Angiotensinogen; Animals; Cattle; Dogs; Endopeptidases

1976
Kallikrein, kinins, and the kidney: what's going on in there?
    The Journal of laboratory and clinical medicine, 1978, Volume: 91, Issue:5

    Topics: Aldosterone; Humans; Hypertension; Kallikreins; Kidney; Kinins; Nephrons; Peptidyl-Dipeptidase A; Pr

1978
Spirolactones: clinical and pharmacologic studies.
    Advances in nephrology from the Necker Hospital, 1977, Volume: 7

    Topics: Aldosterone; Animals; Binding, Competitive; Canrenoic Acid; Canrenone; Diuresis; Humans; Hyperaldost

1977
Mineralocorticoids in normal and hypertensive pregnancies.
    Seminars in perinatology, 1978, Volume: 2, Issue:1

    Topics: Adrenocorticotropic Hormone; Aldosterone; Desoxycorticosterone; Female; Humans; Hypertension; Pregna

1978
Control of aldosterone secretion.
    Clinical science (London, England : 1979), 1979, Volume: 56, Issue:5

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Dogs; Humans; Hyperaldosteronism;

1979
Interrelations between various blood pressure regulatory systems and the mosaic theory of hypertension.
    Biochemical pharmacology, 1979, Oct-01, Volume: 28, Issue:19

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Volume; Brain; Humans; Hypertension; Hyp

1979
[Pathogenetic mechanisms of primary arterial hypertension in adolescents].
    Terapevticheskii arkhiv, 1979, Volume: 51, Issue:12

    Topics: Adolescent; Age Factors; Aldosterone; Animals; Catecholamines; Cyclic AMP; Hemodynamics; Humans; Hyp

1979
Renin-angiotensin system.
    The New England journal of medicine, 1975, Feb-06, Volume: 292, Issue:6

    Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Amino Acid Sequence; Angiotens

1975
Primary aldosteronism.
    The Urologic clinics of North America, 1977, Volume: 4, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism;

1977
Experimental toxemia of pregnancy: review and speculation.
    Pathology annual, 1977, Volume: 12 Pt 2

    Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Dogs; Endocrine Glands; Female; Humans

1977
Role of the adrenal cortex and sodium in the pathogenesis of human hypertension.
    Canadian Medical Association journal, 1978, Mar-04, Volume: 118, Issue:5

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Animals; Dogs; Female; Humans;

1978
[The effect of an angiotensin antagonist on blood pressure, renin and aldosterone secretion and its pathogenetic importance].
    Schweizerische medizinische Wochenschrift. Supplementum, 1978, Issue:7

    Topics: Aldosterone; Angiotensin II; Aortic Valve Stenosis; Bartter Syndrome; Binding, Competitive; Blood Pr

1978
[Pathophysiological aspects of the renin-angiotensin-aldosterone system].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Adrenal Insufficiency; Aldosterone; Angiotensin II; Bartter Syndrome; Contraceptives, Oral; Half-Lif

1977
Significance of renin and angiotensin in hypertension.
    Cardiovascular clinics, 1978, Volume: 9, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin I; Angiotensin II; Female; Humans; Hyper

1978
[The renin-angiotensin-aldosterone system in diabetics].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1978, Jul-31, Volume: 33, Issue:31

    Topics: Aldosterone; Angiotensin II; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic N

1978
[Pathogenesis of arterial hypertension with a low renin activity in the blood plasma].
    Kardiologiia, 1978, Volume: 18, Issue:11

    Topics: Adolescent; Adult; Age Factors; Aged; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteroni

1978
[Primary aldosteronism--aldosterone-induced sodium storing hypertension--symptoms and differential diagnosis].
    Nihon rinsho. Japanese journal of clinical medicine, 1979, Volume: 37, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Alkalosis; Animals; Diagnosis, Differential; Dogs; F

1979
Aging and the cardiovascular system.
    Acta cardiologica, 1978, Volume: 33, Issue:6

    Topics: Aged; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Cardiac Output; C

1978
Pharmacologic interruption of the renin-angiotensin system.
    Annual review of pharmacology and toxicology, 1979, Volume: 19

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Kidney; Renin; Structure

1979
An apraisal of the role of aldosterone and the sympathetic nervous system in essential hypertension.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1979, Volume: 11, Issue:6

    Topics: Aldosterone; Animals; Disease Models, Animal; Humans; Hyperaldosteronism; Hypertension; Sympathetic

1979
Angiotensin as a renal, adrenal, and cardiovascular hormone: responses to saralasin in normal man and in essential and secondary hypertension.
    Kidney international. Supplement, 1979, Issue:9

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressu

1979
Low renin hypertension: a current review of definitions and controversies.
    American heart journal, 1979, Volume: 98, Issue:5

    Topics: Aging; Aldosterone; Antihypertensive Agents; Black People; Electrolytes; Female; Humans; Hypertensio

1979
[Prostaglandins, kallikrein-kinin and dopamine. Practical implications of this vasodilator-natriuretic system].
    L'union medicale du Canada, 1979, Volume: 108, Issue:6

    Topics: Aldosterone; Angiotensin II; Anti-Inflammatory Agents; Arachidonic Acids; Bartter Syndrome; Bradykin

1979
[Renin-angiotensin-aldosterone system: the present status and problems].
    Vutreshni bolesti, 1979, Volume: 18, Issue:6

    Topics: Aldosterone; Angiotensin II; Animals; Enzyme Activation; Enzyme Precursors; Feedback; Humans; Hypera

1979
[The adrenergic system in essential arterial hypertension].
    Recenti progressi in medicina, 1979, Volume: 67, Issue:1

    Topics: Adrenal Glands; Aldosterone; Animals; Catecholamines; Central Nervous System; Humans; Hypertension;

1979
Salt, volume and the prevention of hypertension.
    Circulation, 1976, Volume: 53, Issue:4

    Topics: Adult; Age Factors; Aldosterone; Animals; Culture; Diet, Sodium-Restricted; Diuretics; Extracellular

1976
Interrelations of renin, angiotensin II, and sodium in hypertension and renal failure.
    Annual review of medicine, 1976, Volume: 27

    Topics: Acute Kidney Injury; Aldosterone; Angiotensin II; Animals; Blood Pressure; Glomerular Filtration Rat

1976
Propranolol, renin and hypertension: a review.
    Postgraduate medical journal, 1976, Volume: 52 Suppl 4

    Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Child; Clinical Trials as Topic; Female; Human

1976
Cardiovascular and renal effects of head-out water immersion in man: application of the model in the assessment of volume homeostasis.
    Circulation research, 1976, Volume: 39, Issue:5

    Topics: Aldosterone; Blood Volume; Diuresis; Extracellular Space; Hemodynamics; Hemostasis; Humans; Hydrosta

1976
[Determination of aldosterone and other mineralocorticoids].
    Nihon rinsho. Japanese journal of clinical medicine, 1976, Volume: 34 suppl

    Topics: Adolescent; Adult; Age Factors; Aldosterone; Child; Child, Preschool; Circadian Rhythm; Diet; Humans

1976
[Clinical aspects of hypertension under contraceptive steroids].
    Fortschritte der Medizin, 1976, Dec-02, Volume: 94, Issue:34

    Topics: Adult; Aldosterone; Angiotensin II; Black or African American; Black People; Contraceptives, Oral; E

1976
Angiotensin antagonists as diagnostic and pharmacologic tools.
    Progress in biochemical pharmacology, 1976, Volume: 12

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Kidney; Kinetics; Propranolol; Re

1976
The second Volhard Lecture: The use of blocking agents to define the functions of the renin--angiotensin system.
    Clinical science and molecular medicine. Supplement, 1975, Volume: 2

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Calcium; Dogs; Hypertension; Hypertension, Ren

1975
Vasopressor substances in normal and abnormal pregnancy.
    European journal of obstetrics, gynecology, and reproductive biology, 1975, Volume: 5, Issue:1-2

    Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Arginine Vasopressin; Catecholamines; Female;

1975
Complications of systemic contraceptive agents: hypertension.
    The Western journal of medicine, 1975, Volume: 122, Issue:1

    Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Drug Combination

1975
Aldosterone and renin in essential hypertension.
    Canadian Medical Association journal, 1975, Sep-06, Volume: 113, Issue:5

    Topics: 18-Hydroxydesoxycorticosterone; Adult; Age Factors; Aldosterone; Angiotensin II; Clinical Trials as

1975
[Oral contraceptives and hypertension. A review].
    Ugeskrift for laeger, 1975, Oct-13, Volume: 137, Issue:42

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Female; Hemodynamics; Humans; Hyp

1975
Inter-relationships between plasma angiotensin II, arterial pressure, aldosterone and exchangeable sodium in normotensive and hypertensive man.
    Journal of steroid biochemistry, 1975, Volume: 6, Issue:5

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Hy

1975
[Pathophysiology of hypertension].
    Zeitschrift fur Allgemeinmedizin, 1975, Nov-30, Volume: 51, Issue:33

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Blood Pressure; Hemodynamics; Humans; Hypertension; Hyp

1975
Aldosterone-specific membrane receptors and rapid non-genomic actions of mineralocorticoids.
    Molecular and cellular endocrinology, 1992, Volume: 90, Issue:1

    Topics: Aldosterone; Animals; Biological Transport; Carrier Proteins; Cell Size; Desoxycorticosterone; Dogs;

1992
Aldosterone regulation of gene transcription leading to control of ion transport.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:3

    Topics: Aldosterone; Biological Transport; Colon; Hypertension; Ion Channels; Kidney; Potassium; Receptors,

1992
Cellular calcium and magnesium metabolism in the pathophysiology and treatment of hypertension and related metabolic disorders.
    The American journal of medicine, 1992, Aug-31, Volume: 93, Issue:2A

    Topics: Aldosterone; Blood Glucose; Blood Pressure; Calcium; Calcium Channel Blockers; Cardiomegaly; Diabete

1992
[The characteristics of the regulation of aldosterone secretion (a review of the literature)].
    Vrachebnoe delo, 1991, Issue:2

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Receptors,

1991
What is the role of the central nervous system in mineralocorticoid hypertension?
    American journal of hypertension, 1991, Volume: 4, Issue:4 Pt 1

    Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Blood Vessels; Central Nervous System; Humans;

1991
Vascular and cardiac actions of aldosterone and spironolactone.
    Zeitschrift fur Kardiologie, 1991, Volume: 80 Suppl 7

    Topics: Aldosterone; Animals; Electrocardiography; Humans; Hypertension; Muscle, Smooth, Vascular; Myocardia

1991
Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system.
    Circulation, 1991, Volume: 83, Issue:6

    Topics: Aldosterone; Animals; Cardiomegaly; Fibrosis; Humans; Hypertension; Models, Cardiovascular; Myocardi

1991
The renin-angiotensin system: renal actions and blood pressure regulation.
    Comprehensive therapy, 1991, Volume: 17, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dogs; Humans; Hypertension; Kidney; Natriuresi

1991
17 alpha-hydroxylation deficiency.
    Endocrinology and metabolism clinics of North America, 1991, Volume: 20, Issue:2

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Child; Female; Humans; Hypertension

1991
Dysregulation of aldosterone secretion and its relationship to the pathogenesis of essential hypertension.
    Endocrinology and metabolism clinics of North America, 1991, Volume: 20, Issue:2

    Topics: Aldosterone; Angiotensin II; Homeostasis; Humans; Hypertension; Renin; Sodium, Dietary

1991
Corticosteroids, kidneys, sweet roots and dirty drugs.
    Molecular and cellular endocrinology, 1991, Volume: 78, Issue:1-2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Aldosterone; Animals; Carbenoxolone;

1991
Functional derangements in the regulation of aldosterone secretion in hypertension.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 18, Issue:5 Suppl

    Topics: Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Kidney; Renin; Sodium; Sodium, Dietary

1991
The causes of raised blood pressure in insulin-dependent and non-insulin-dependent diabetes.
    Journal of human hypertension, 1991, Volume: 5, Issue:4

    Topics: Aldosterone; Blood Pressure; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopat

1991
Non-modulating hypertension. A subset of sodium-sensitive hypertension.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:1 Suppl

    Topics: Aldosterone; Homeostasis; Humans; Hypertension; Renal Circulation; Sodium

1991
Post transplant hypertension.
    Journal of human hypertension, 1991, Volume: 5, Issue:1

    Topics: Aldosterone; Cyclosporins; Humans; Hypertension; Kidney; Kidney Transplantation; Postoperative Care;

1991
Dopaminergic regulation of aldosterone secretion. Biochemical mechanisms and pharmacology.
    American journal of hypertension, 1990, Volume: 3, Issue:6 Pt 2

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Biomechanical Phenomena; Cyclic AMP; Dihydroer

1990
Diabetes mellitus, the renin-angiotensin system, and angiotensin-converting enzyme inhibition.
    Nephron, 1990, Volume: 55 Suppl 1

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Diab

1990
Primary hyperaldosteronism.
    The American journal of the medical sciences, 1990, Volume: 300, Issue:3

    Topics: Aldosterone; Desoxycorticosterone; Electrolytes; Humans; Hyperaldosteronism; Hypertension; Kidney Tu

1990
[The renin-angiotensin-aldosterone (RAA) system in endocrine diseases].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1990, Jul-01, Volume: 43, Issue:13

    Topics: Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Cushing Syndrome; Endocrine System Diseases; H

1990
A study of urinary and intracellular sodium and potassium, renin, aldosterone, and hypertension in blacks and Indians in Natal.
    Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 2

    Topics: Aldosterone; Black or African American; Black People; Erythrocytes; Humans; Hypertension; India; Pot

1990
Natriuretic effect of calcium antagonists.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 4

    Topics: Aldosterone; Animals; Calcium Channel Blockers; Glomerular Filtration Rate; Humans; Hypertension; Ki

1985
Acute inhibition of the renin-angiotensin system: interest and limits to detect surgically curable hypertension.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 4

    Topics: Aldosterone; Blood Pressure; Captopril; Humans; Hypertension; Renin; Renin-Angiotensin System; Saral

1985
Altered Ca-dependent fluxes of 42K in rat aorta during aldosterone-salt hypertension.
    Progress in clinical and biological research, 1986, Volume: 219

    Topics: Aldosterone; Animals; Aorta; Calcium; Hypertension; Ion Channels; Rats; Sodium Chloride

1986
Dopaminergic receptor mechanisms modulating the renin-angiotensin system and aldosterone secretion: an overview.
    Journal of cardiovascular pharmacology, 1989, Volume: 14 Suppl 8

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Depression, Chemical; Dopamine

1989
Atrial natriuretic peptide. An important factor in sodium and blood pressure regulation.
    Lancet (London, England), 1989, Apr-01, Volume: 1, Issue:8640

    Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Homeostasis; Humans; Hypertension; Natriures

1989
Corcoran lecture: the case for or against salt in hypertension. Arthur Curtis Corcoran, MD (1909-1965). Tribute and prelude to Corcoran Lecture of 1988.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 13, Issue:6 Pt 2

    Topics: Aldosterone; Animals; Blood Pressure; Humans; Hypertension; Sodium; Sodium Chloride

1989
The renin-angiotensin system. Normal physiology and changes in older hypertensives.
    Journal of the American Geriatrics Society, 1989, Volume: 37, Issue:8

    Topics: Aging; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Natriuresis; Renin-Angiote

1989
Homeostatic regulation of potassium excretion.
    Journal of hypertension, 1989, Volume: 7, Issue:6

    Topics: Aldosterone; Animals; Central Nervous System; Cerebral Ventricles; Circadian Rhythm; Desoxycorticost

1989
Sodium-sensitive hypertension. Implications of pathogenesis for therapy.
    American journal of hypertension, 1989, Volume: 2, Issue:10

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diet, Sodium-

1989
Role of angiotensin and aldosterone in the pathogenesis of hypertension in insulin-dependent diabetes mellitus?
    Diabete & metabolisme, 1989, Volume: 15, Issue:5 Pt 2

    Topics: Aldosterone; Diabetes Mellitus, Type 1; Humans; Hypertension; Renin-Angiotensin System

1989
Antihypertensive mechanisms of beta-adrenoceptor blockade: a review.
    Clinical and experimental hypertension. Part A, Theory and practice, 1985, Volume: 7, Issue:1

    Topics: Adrenal Medulla; Adrenergic beta-Antagonists; Aldosterone; Animals; Antihypertensive Agents; Blood P

1985
Biochemical indices associated with meditation practice: a literature review.
    Neuroscience and biobehavioral reviews, 1985,Winter, Volume: 9, Issue:4

    Topics: Aldosterone; Blood Circulation; Catecholamines; Cholesterol; Dopamine beta-Hydroxylase; Growth Hormo

1985
Atrial natriuretic factor. A newly discovered hormone with significant clinical implications.
    Drugs, 1986, Volume: 31, Issue:5

    Topics: Adenylyl Cyclases; Adrenal Cortex; Aldosterone; Amino Acid Sequence; Animals; Antihypertensive Agent

1986
Atrial natriuretic peptide: a new factor in hormonal control of blood pressure and electrolyte homeostasis.
    Annual review of medicine, 1986, Volume: 37

    Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Circulation; Blood Pressure;

1986
Pharmacological influences on aldosterone secretion.
    Journal of steroid biochemistry, 1987, Volume: 27, Issue:4-6

    Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Dopamine; Histamine; Humans; Hypera

1987
Atrial natriuretic hormone: a regulator of blood pressure and volume homeostasis.
    Kidney international. Supplement, 1988, Volume: 25

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Blood Volume; Hemodynamics; Homeost

1988
[Diet therapy of obese and hypertensive patients. Efficacy and modality of the hypotensive action].
    La Clinica terapeutica, 1987, Feb-15, Volume: 120, Issue:3

    Topics: Aldosterone; Diet, Sodium-Restricted; Energy Intake; Humans; Hypertension; Obesity; Renin

1987
The renin-angiotensin system and body function.
    Archives of internal medicine, 1985, Volume: 145, Issue:8

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinoge

1985
Syndrome of hypertension and hyperkalemia with normal glomerular filtration rate.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Bicarbonates; Blood Pressure; Child; Diet, Sodium-Restricted; Diuret

1986
Role of exogenous factors in alterations of red cell Na+-Li+ exchange and Na+-K+ cotransport in essential hypertension, primary hyperaldosteronism, and hypokalemia.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1986, Volume: 180

    Topics: Adult; Aldosterone; Biological Transport, Active; Body Weight; Erythrocytes; Fatty Acids; Female; Ge

1986
Potassium metabolism and hypertension.
    Journal of clinical hypertension, 1985, Volume: 1, Issue:4

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aldosterone; Animals; Catecholamines;

1985
[Angiotensin converting enzyme: its levels and its effect on blood pressure regulation].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1986, Apr-15, Volume: 39, Issue:8

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Bradykinin; Humans; Hypertension; Peptidyl-Dipeptidase

1986
Aldosterone, calcium, and hypertension.
    American journal of nephrology, 1986, Volume: 6 Suppl 1

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel Blockers

1986
Clinical applications of antimineralocorticoids.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:4B

    Topics: Aldosterone; Angiotensin II; Ascites; Glucose; Heart Failure; Humans; Hypertension; Liver Cirrhosis;

1988
[Vasoactive substances in normal pregnancy and in pregnancy complicated by gestosis].
    Minerva ginecologica, 1988, Volume: 40, Issue:8

    Topics: Aldosterone; Female; Humans; Hypertension; Kallikreins; Pre-Eclampsia; Pregnancy; Pregnancy Complica

1988
Hypertension: relating drug therapy to pathogenetic mechanisms.
    Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1988, Volume: 32

    Topics: Aldosterone; Angiotensinogen; Catecholamines; Creatinine; Humans; Hydrocortisone; Hyperaldosteronism

1988
Low-renin hypertension of childhood.
    Pediatric nephrology (Berlin, Germany), 1987, Volume: 1, Issue:1

    Topics: Adolescent; Aldosterone; Child; Child, Preschool; Humans; Hypertension; Infant; Renin

1987
Animal models of mineralocorticoid resistance.
    Advances in experimental medicine and biology, 1986, Volume: 196

    Topics: Aldosterone; Animals; Corticosterone; Desoxycorticosterone; Dexamethasone; Disease Models, Animal; D

1986
[Current status and prospects of the laboratory diagnosis of arterial hypertension].
    Przeglad lekarski, 1986, Volume: 43, Issue:3

    Topics: Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Catecholamines; Diagnosis, Differential; Human

1986
The renin-angiotensin system and long-term regulation of arterial pressure.
    Journal of hypertension, 1986, Volume: 4, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Fluids; Feedback; Hypertension; Kidney; N

1986
Regulation of arterial pressure: role of pressure natriuresis and diuresis.
    Federation proceedings, 1986, Volume: 45, Issue:13

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Diuresis; Homeostasis; Humans; Hypertension; K

1986
Disorders of mineralocorticoid activity.
    Clinics in endocrinology and metabolism, 1985, Volume: 14, Issue:1

    Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Specime

1985
[Hypertensive syndrome in kidney diseases].
    Klinicheskaia meditsina, 1985, Volume: 63, Issue:4

    Topics: Aldosterone; Blood Pressure; Blood Volume; Diagnosis, Differential; Diuresis; Humans; Hyperaldostero

1985
Calcium antagonists in the treatment of hypertension: a critical overview.
    Advances in nephrology from the Necker Hospital, 1985, Volume: 14

    Topics: Aldosterone; Blood Pressure; Calcium; Calcium Channel Blockers; Cardiac Output; Catecholamines; Hear

1985
The renal pressor system in human pregnancy.
    The Journal of reproductive medicine, 1972, Volume: 8, Issue:3

    Topics: Aldosterone; Alpha-Globulins; Angiotensin II; Contraceptives, Oral; Female; Humans; Hypertension; Ju

1972
[Hemodynamic and hormonologic basis of the treatment of arterial hypertension].
    Archives des maladies du coeur et des vaisseaux, 1974, Volume: 67, Issue:10

    Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Cardiac Output; C

1974
Inhibitors of adrenal steroid biosynthesis.
    Annual review of pharmacology, 1970, Volume: 10

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide

1970
[Metabolism of corticoids].
    Nihon rinsho. Japanese journal of clinical medicine, 1974, Nov-10, Volume: 32, Issue:11

    Topics: Adipose Tissue; Adrenal Cortex Hormones; Aldosterone; Animals; Arthritis, Rheumatoid; Brain; Chemica

1974
Assessment of adrenocortical function.
    The New England journal of medicine, 1971, Sep-23, Volume: 285, Issue:13

    Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenal Glands; Adrenal Insufficiency; Adult; Aldoster

1971
Aldosteronism and hypertension.
    Progress in cardiovascular diseases, 1965, Volume: 8, Issue:2

    Topics: Aldosterone; Angiotensin II; Hyperaldosteronism; Hypertension; Renin

1965
[Activity of renin-angiotensin in normal and abnormal conditions].
    Saishin igaku. Modern medicine, 1967, Volume: 22, Issue:5

    Topics: Adrenal Gland Diseases; Aldosterone; Angiotensin II; Humans; Hypertension; Kidney; Kidney Diseases;

1967
Aldosterone in childhood.
    Advances in pediatrics, 1968, Volume: 15

    Topics: Adolescent; Adrenal Glands; Adrenal Insufficiency; Adrenocortical Hyperfunction; Adrenocorticotropic

1968
[The importance of angiotensin in clinical practice].
    Zeitschrift fur arztliche Fortbildung, 1966, Nov-15, Volume: 60, Issue:21

    Topics: Aldosterone; Anaphylaxis; Angiotensin II; Animals; Blood Pressure; Glomerular Filtration Rate; Human

1966
Pathophysiology of hypertension.
    The Medical clinics of North America, 1967, Volume: 51, Issue:1

    Topics: Aldosterone; Angiotensin II; Aorta; Carotid Sinus; Humans; Hypertension; Hypothalamus; Juxtaglomerul

1967
Tissue hormones: angiotensin, bradykinin and the regulation of regional blood flows.
    The Medical clinics of North America, 1968, Volume: 52, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Autonomic Nervous System; Bradykinin; Calcium; Catecholamines;

1968
[Recent concept of primary aldosteronism].
    Saishin igaku. Modern medicine, 1967, Nov-10, Volume: 22, Issue:11

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Insufficiency; Aldosterone; Angiotensin II; Carbohydrate M

1967
[The renin-angiotensin-aldosterone system in late gestosis].
    Ceskoslovenska fysiologie, 1968, Volume: 17, Issue:2

    Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Juxtaglomerular Apparatus; Pre-Eclampsia;

1968
[Sodium in experimental hypertension].
    Pathologie et biologie, 1965, Volume: 13, Issue:21

    Topics: Aldosterone; Angiotensin II; Animals; Desoxycorticosterone; Extracellular Space; Hypertension; Hyper

1965
[Hypokalemic hypertension].
    Der Internist, 1968, Apr-25, Volume: 9, Issue:3

    Topics: Acid-Base Equilibrium; Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Angiotensin II; Diureti

1968
Recent developments in pathophysiologic studies of the renin-angiotensin system.
    The New England journal of medicine, 1969, Jan-16, Volume: 280, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Amino Acid Sequence; Angiotensin II; Biological Assay

1969
Neurogenic control of the blood pressure in hypertension.
    Cardiologia, 1967, Volume: 51, Issue:4

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Central Nervous System; Humans; Hypertension; Kidney; P

1967
[Recent data on the physiopathologic metabolism of aldosterone].
    Exposes annuels de biochimie medicale, 1967, Volume: 28

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Aorta; Edema; Female; Heart Disea

1967
Control of aldosterone secretion by the renin-angiotensin system and by corticotropin.
    Advances in internal medicine, 1968, Volume: 14

    Topics: Addison Disease; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Female; Humans;

1968
[Renin--facts and hypotheses].
    Polskie Archiwum Medycyny Wewnetrznej, 1968, Volume: 41, Issue:5

    Topics: Acid-Base Equilibrium; Aldosterone; Amino Acids; Angiotensin II; Animals; Fibrinolysis; Humans; Hype

1968
[Experimental bases of the pathophysiology of the renin-angiotensin system].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1968, Volume: 74

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Female; Humans; Hyperaldosteronism; Hypertensi

1968
[Renin-angiotensin-aldosterone system in blood pressure regulation disorders].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1968, Volume: 74

    Topics: Adult; Aldosterone; Angiotensin II; Child; Electrolytes; Female; Humans; Hydrogen-Ion Concentration;

1968
[Adrenal cortex function tests and their interpretation].
    Nihon rinsho. Japanese journal of clinical medicine, 1969, Volume: 27, Issue:2

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Aldosterone; Androg

1969
[Significance of renin in physiopathology and diagnosis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1969, Apr-01, Volume: 24, Issue:7

    Topics: Acute Kidney Injury; Aldosterone; Angiography; Angiotensin II; Humans; Hyperaldosteronism; Hypertens

1969
[The role of renin in the pathophysiology and diagnosis, excluding pregnancy and its complications].
    Ginekologia polska, 1969, Volume: 40, Issue:5

    Topics: Aldosterone; Angiotensin II; Extracellular Space; Humans; Hyperaldosteronism; Hypertension; Kidney;

1969
[Changes in renal hemodynamics and function in cardiac insufficiency].
    Kardiologiia, 1969, Volume: 9, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Arteriovenous Anastomosis; Cardiac Volume; Catecholamines; Diu

1969
[New endocrine disorders attracting current interest--adrenal system].
    Horumon to rinsho. Clinical endocrinology, 1969, Volume: 17, Issue:5

    Topics: Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Ho

1969
[Hyperaldosteronism and the renin-angiotensin system].
    Saishin igaku. Modern medicine, 1969, Volume: 24, Issue:5

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Animals; Catecholamines

1969
[Pathogenesis of arterial hypertension. Current trends and prospectives].
    Polskie Archiwum Medycyny Wewnetrznej, 1969, Volume: 43, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Blood Vessels; Cardiac Output; Catecholamines; Humans; Hyperte

1969
[The renin--angiotensin--aldosterone system].
    Kardiologiia, 1969, Volume: 9, Issue:9

    Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Animals; Arteries; Blood Pressure; Blood Volum

1969
[Renin-angiotensin-aldosterone system from the pathophysiological viewpoint].
    Klinische Wochenschrift, 1969, Dec-01, Volume: 47, Issue:23

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Catecholamines; Cats; Chemical

1969
[Endocrine function tests for etiological diagnosis of hypertensive patients].
    Horumon to rinsho. Clinical endocrinology, 1970, Volume: 18, Issue:8

    Topics: Adult; Aldosterone; Angiotensin II; Catecholamines; Cushing Syndrome; Endocrine Glands; Glucocortico

1970
[Role of the adrenal cortex in the pathogenesis of hypertension].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1970, Nov-01, Volume: 90, Issue:21

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Hydrocortisone; Hyperaldosteronism; Hypertension; Renin

1970
[Role of prostaglandins in the pathogenesis of arterial hypertension].
    Polskie Archiwum Medycyny Wewnetrznej, 1970, Volume: 45, Issue:6

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Kidney; Muscle, Smooth; Prostaglandins; Renin

1970
[17-alpha-hydroxylase deficiency].
    Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adul

1971
[Hypertension caused by oral contraceptives].
    Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29, Issue:3

    Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Female; Humans; Hypertension; Renin

1971
[Juxtaglomerular cell tumor and aldosterone-secreting renal tumor].
    Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29, Issue:3

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Female; Hemangiope

1971
Hypertension and chronic renal failure.
    British medical bulletin, 1971, Volume: 27, Issue:2

    Topics: Aldosterone; Angiotensin II; Body Weight; Humans; Hypertension; Hypertension, Renal; Kidney Failure,

1971
The relationship between angiotensin and aldosterone.
    Advances in metabolic disorders, 1971, Volume: 5

    Topics: Adrenal Gland Neoplasms; Aldosterone; Alkalosis; Angiotensin II; Animals; Humans; Hyperaldosteronism

1971
Perspectives in aldosterone and renin control.
    Australian and New Zealand journal of medicine, 1971, Volume: 1, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Bionics; Glomerular Filtration Rate; Humans; Hyperaldosteronis

1971
[On mechanisms acting upon arterial blood pressure and sodium metabolism, particularly during pregnancy].
    Ginekologia polska, 1971, Volume: 42, Issue:6

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Feedback; Female; Humans; Hypertension; Kidney

1971
[The renin-angiotensin-aldosterone system in arterial hypertension].
    Kardiologia polska, 1971, Volume: 14, Issue:3

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Diagnosis, Differential; Feedback; Glomeru

1971
[The renin-angiotensin-aldosterone system in arterial hypertension].
    Kardiologia polska, 1971, Volume: 14, Issue:3

    Topics: Adenoma; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Glomerular Filtration Rate; Homeo

1971
[Arterial hypertension and oral contraceptives].
    Lyon medical, 1971, Dec-12, Volume: 226, Issue:19

    Topics: Adolescent; Adult; Age Factors; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure

1971
Circulation: overall regulation.
    Annual review of physiology, 1972, Volume: 34

    Topics: Aldosterone; Angiotensin II; Blood Circulation; Blood Pressure; Body Fluids; Cardiac Output; Heart F

1972
The adrenal cortex.
    Annual review of physiology, 1972, Volume: 34

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Ascorbic

1972
Physiologic characteristics of hypertension.
    The American journal of medicine, 1972, Volume: 52, Issue:5

    Topics: Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Autonomic Nervous System; Blood Volume; Cardia

1972
Renin, angiotensin and aldosterone system in pathogenesis and management of hypertensive vascular disease.
    The American journal of medicine, 1972, Volume: 52, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Angiotensin II; Contraceptives, Oral;

1972
The cardiovascular effects of oral contraceptives.
    Modern concepts of cardiovascular disease, 1972, Volume: 41, Issue:8

    Topics: Aldosterone; Angiotensin II; Blood Coagulation; Blood Flow Velocity; Blood Vessels; Cardiovascular S

1972
Salt, water, and rest as a preventative for toxemia of pregnancy. A commentary and review.
    The Journal of reproductive medicine, 1972, Volume: 9, Issue:5

    Topics: Aldosterone; Angiotensin II; Blood Volume; Body Weight; Diabetes Insipidus; Diuresis; Diuretics; Ede

1972
[Abnormalities of sodium and water metabolism with special reference to hypertensive diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:11

    Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hype

1972
Endocrine causes of hypertension.
    The Journal of the Kentucky Medical Association, 1973, Volume: 71, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Angiotensin II; Catecholamines;

1973
The role of renal factors in the pathogenesis of experimental hypertension.
    International review of experimental pathology, 1973, Volume: 12

    Topics: Aldosterone; Angiotensin II; Animals; Cadmium; Cattle; Chronic Disease; Embolism; Glomerulonephritis

1973
The physiology of renin.
    Archives of internal medicine, 1973, Volume: 131, Issue:6

    Topics: Aldosterone; Angiotensin II; Edema; Extracellular Space; Female; Glomerular Filtration Rate; Humans;

1973
Significance of the effects of prostaglandins on renal and adrenal function in man.
    Prostaglandins, 1973, Volume: 3, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Blood Pressure; Body Temperature; Cyclic AMP;

1973
[Some new aspects of the renin-angiotensin system].
    L'union medicale du Canada, 1973, Volume: 102, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Brain Chemistry; Dogs; Female; Humans; Hypertension; Mineraloc

1973
[Renin-secreting tumors].
    Deutsche medizinische Wochenschrift (1946), 1973, Oct-05, Volume: 98, Issue:40

    Topics: Aldosterone; Carcinoma, Small Cell; Diagnosis, Differential; Humans; Hypertension; Juxtaglomerular A

1973
Aldosterone: review of its physiology and diagnostic aspects of primary aldosteronism.
    Metabolism: clinical and experimental, 1973, Volume: 22, Issue:12

    Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone;

1973
The pathophysiology of renin.
    Clinical symposia (Summit, N.J. : 1957), 1973, Volume: 25, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal;

1973
[Na metabolism anomaly in essential hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1973, Volume: 31, Issue:11

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Natriuresis; Plasma Volume; Renin; Sodium

1973
[Renin-angiotensin-aldosterone system in essential hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1973, Volume: 31, Issue:11

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Age

1973
[Renin-angiotensin-(aldosterone)-system-clinical aspects].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, Dec-15, Volume: 28, Issue:24

    Topics: Acute Kidney Injury; Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Aldosterone; Angioten

1973
Perspectives on the renin-angiotensin-aldosterone system in hypertension.
    Metabolism: clinical and experimental, 1974, Volume: 23, Issue:3

    Topics: Aldosterone; Angiotensin II; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal;

1974
The role of the renal medulla in hypertension.
    Advances in internal medicine, 1974, Volume: 19

    Topics: Aldosterone; Angiotensin II; Animals; Cardiac Output; Desoxycorticosterone; Extracellular Space; Hum

1974
[Primary hypo- and hyperreninism].
    Der Internist, 1974, Volume: 15, Issue:3

    Topics: Addison Disease; Adolescent; Adult; Aldosterone; Angiotensin II; Blood Volume; Diagnosis, Differenti

1974
The renin-angiotensin system (first of two parts).
    The New England journal of medicine, 1974, Aug-22, Volume: 291, Issue:8

    Topics: Aldosterone; Angiotensin II; Animals; Autonomic Nervous System; Biological Assay; Blood Pressure; Ch

1974
[Primary aldosteronism].
    Nihon rinsho. Japanese journal of clinical medicine, 1973, Volume: 31, Issue:11

    Topics: Aldosterone; Angiotensin II; Desoxycorticosterone; Glucocorticoids; Humans; Hyperaldosteronism; Hype

1973
Low-renin hypertension.
    Kidney international, 1974, Volume: 5, Issue:5

    Topics: Adrenal Glands; Age Factors; Aldosterone; Angiotensin II; Blood Volume; Extracellular Space; Female;

1974
[Oral contraceptives and arterial hypertension].
    Medizinische Klinik, 1974, Dec-13, Volume: 69, Issue:50

    Topics: Aldosterone; Angiotensin II; Animals; Blood Circulation; Blood Pressure; Body Weight; Contraceptives

1974
[Changes in the hemodynamics of patients with hypertension].
    Vutreshni bolesti, 1974, Volume: 13, Issue:5

    Topics: Aldosterone; Angiotensin II; Blood Flow Velocity; Blood Pressure; Cardiac Output; Heart; Hemodynamic

1974
Sodium metabolism, aldosterone and the hypertensive disorders of pregnancy.
    The Journal of reproductive medicine, 1972, Volume: 8, Issue:3

    Topics: Aldosterone; Diuretics; Estrogens; Female; Humans; Hypertension; Posture; Pre-Eclampsia; Pregnancy;

1972
Adrenal mineralocorticoids causing hypertension.
    The American journal of medicine, 1972, Volume: 52, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Corticosterone; Desoxyc

1972
Instinct, appetites and medicine.
    Australian and New Zealand journal of medicine, 1972, Volume: 2, Issue:2

    Topics: Aldosterone; Animals; Appetite; Biological Evolution; Disorders of Sex Development; Female; Humans;

1972
[Diagnosis and therapy of primary hyperaldosteronism].
    Schweizerische medizinische Wochenschrift, 1972, Jul-29, Volume: 102, Issue:30

    Topics: Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; H

1972
Renin and hypertension: a review article.
    The Central African journal of medicine, 1973, Volume: 19, Issue:4

    Topics: Aldosterone; Humans; Hydrochlorothiazide; Hypertension; Juxtaglomerular Apparatus; Kidney Diseases;

1973
Aldosteronism updated.
    The Journal of urology, 1973, Volume: 110, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Dexamethasone; Diagnosis, Differentia

1973
[Mineralocorticoids and essential hypertension].
    L'union medicale du Canada, 1973, Volume: 102, Issue:4

    Topics: Adrenal Glands; Aldosterone; Black or African American; Corticosterone; Desoxycorticosterone; Diet;

1973
Improvements of metabolic and diagnostic assessment of human renal allotransplants.
    Surgery annual, 1972, Volume: 4

    Topics: Adrenal Glands; Aldosterone; Anemia; Biopsy, Needle; Cholinesterases; Erythropoietin; Fibrin; Graft

1972
[Primary hypertension with low plasma renin level].
    Deutsche medizinische Wochenschrift (1946), 1973, Oct-19, Volume: 98, Issue:42

    Topics: Aldosterone; Blood Pressure; Dexamethasone; Diagnosis, Differential; Female; Germany, West; Humans;

1973
The use of spironolactone in the diagnosis and the treatment of hypertension associated with mineralocorticoid excess.
    American heart journal, 1973, Volume: 86, Issue:3

    Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Aldosterone; Antihypertensive Agents; Carc

1973
[Disturbances in the endocrine functions of the kidneys].
    Lakartidningen, 1973, Sep-26, Volume: 70, Issue:39

    Topics: Aldosterone; Erythropoiesis; Erythropoietin; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney

1973
[Low renin essential hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1973, Volume: 31, Issue:11

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin; Spironolactone; Trichlormet

1973
[Clinical course, diagnosis and treatment of primary hyperaldosteronism].
    Klinicheskaia meditsina, 1974, Volume: 52, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Cushing Syndrome; Diagnosis, Differential; Fe

1974
[Heart diseases, hypertension and hormonal anomaly--with special reference to aldosterone and catecholamine].
    Naika. Internal medicine, 1967, Volume: 19, Issue:3

    Topics: Aldosterone; Catecholamines; Heart Diseases; Humans; Hypertension; Hyperthyroidism

1967
Aldosterone, the adrenal cortex, and hypertension.
    Annual review of medicine, 1968, Volume: 19

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Animals; Bloo

1968
[Abnormal secretion of aldosterone].
    Naika. Internal medicine, 1967, Volume: 20, Issue:3

    Topics: Adrenal Insufficiency; Adrenocortical Hyperfunction; Aldosterone; Animals; Dysautonomia, Familial; E

1967
Shock following acute myocardial infarction. Current understanding of hemodynamic mechanisms.
    Progress in cardiovascular diseases, 1968, Volume: 11, Issue:1

    Topics: Acidosis; Aldosterone; Animals; Arrhythmias, Cardiac; Arteries; Blood Flow Velocity; Blood Pressure;

1968
Commentary on incidence of primary aldosteronism: current estimations based on objective data.
    Archives of internal medicine, 1969, Volume: 123, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Blood Pressure; Desoxycorticosterone;

1969
[Clinical problems in body fluid balance].
    Nihon rinsho. Japanese journal of clinical medicine, 1969, Volume: 27, Issue:4

    Topics: Acid-Base Equilibrium; Aldosterone; Body Fluids; Diabetes Insipidus; Edema; Glomerular Filtration Ra

1969
[Aspect of hormones and hypertension].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1969, Jul-10, Volume: 58, Issue:7

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Catechol

1969
[Approach to the etiological study of essential hypertension].
    Naika. Internal medicine, 1969, Volume: 24, Issue:4

    Topics: Aldosterone; Animals; Catecholamines; Diagnosis, Differential; Hemodynamics; Humans; Hyperaldosteron

1969
[Hypertension and aldosterone].
    Horumon to rinsho. Clinical endocrinology, 1970, Volume: 18, Issue:8

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension

1970
[Relations between aldosterone secretion and hypertension].
    Medicina interna, 1970, Volume: 22, Issue:7

    Topics: Aldosterone; Animals; Humans; Hyperaldosteronism; Hypertension

1970
[Recent knowledge of diseases with abnormal aldosterone secretion].
    Naika hokan. Japanese archives of internal medicine, 1971, Volume: 18, Issue:1

    Topics: Addison Disease; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adult; Aldosterone; A

1971
[Aldosterone (including in the urinary content)--how to read its figures].
    Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29

    Topics: Adrenal Glands; Age Factors; Aldosterone; Blood Chemical Analysis; Circadian Rhythm; Diet; Extracell

1971
[Aldosterone deficiency].
    Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29, Issue:3

    Topics: Adult; Aldosterone; Autonomic Nervous System; Endocrine System Diseases; Heart Failure; Heparin; Hum

1971
[Hypermineralocorticoidism and hypertension].
    Klinische Wochenschrift, 1971, Mar-15, Volume: 49, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Cushing Syndrome; Dexam

1971
[Mineralocorticoid function of the adrenal cortex under normal conditions and in pathology (review of the literature)].
    Voprosy okhrany materinstva i detstva, 1971, Volume: 16, Issue:2

    Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenal Insufficiency; Adrenalectomy; Adult; Aging; Aldoster

1971
[The third factor].
    Naika. Internal medicine, 1971, Volume: 28, Issue:1

    Topics: Aldosterone; Animals; Biological Assay; Dogs; Extracorporeal Circulation; Female; Glomerular Filtrat

1971
[Aldosterone analysis (including urinary aldosterone test): interpretation of the test results].
    Nihon rinsho. Japanese journal of clinical medicine, 1969

    Topics: Adrenal Glands; Adult; Age Factors; Aldosterone; Child; Circadian Rhythm; Diet; Humans; Hyperaldoste

1969
Aldosterone and electrolyte balance in human hypertension.
    Journal of the Royal College of Physicians of London, 1970, Volume: 5, Issue:1

    Topics: Adrenocortical Hyperfunction; Aldosterone; Animals; Corticosterone; Furosemide; Humans; Hyperaldoste

1970
Plasma renin concentration in human hypertension.
    American heart journal, 1967, Volume: 74, Issue:3

    Topics: Aldosterone; Female; Heart Failure; Humans; Hypertension; Hypertension, Malignant; Kidney Failure, C

1967

Trials

473 trials available for aldosterone and Hypertension

ArticleYear
Enhanced Thrombotic Responses Are Associated With Striatin Deficiency and Aldosterone.
    Journal of the American Heart Association, 2021, 11-16, Volume: 10, Issue:22

    Topics: Aldosterone; Animals; Calmodulin-Binding Proteins; Fibrin; Hypertension; Membrane Proteins; Mice; Ne

2021
The renoprotective effect of esaxerenone independent of blood pressure lowering: a post hoc mediation analysis of the ESAX-DN trial.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:2

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyperte

2023
Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension.
    The New England journal of medicine, 2023, 02-02, Volume: 388, Issue:5

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Cytochrome P-450 CYP11B2; Double-Blind Method;

2023
Surgical versus medical treatment for unilateral primary aldosteronism: an alternative to a randomized controlled trial.
    European journal of endocrinology, 2023, 03-02, Volume: 188, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension

2023
CYP11B2 inhibitor dexfadrostat phosphate suppresses the aldosterone-to-renin ratio, an indicator of sodium retention, in healthy volunteers.
    British journal of clinical pharmacology, 2023, Volume: 89, Issue:8

    Topics: Adrenocorticotropic Hormone; Aldosterone; Cytochrome P-450 CYP11B2; Healthy Volunteers; Humans; Hype

2023
Moderate dietary salt restriction improves blood pressure and mental well-being in patients with primary aldosteronism: The salt CONNtrol trial.
    Journal of internal medicine, 2023, Volume: 294, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Sodi

2023
Effect of angiotensin II receptor blocker and salt supplementation on short-term blood pressure variability in type 2 diabetes.
    Journal of human hypertension, 2020, Volume: 34, Issue:2

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Cross-Over Studies; D

2020
A combination of captopril challenge test after saline infusion test improves diagnostic accuracy for primary aldosteronism.
    Clinical endocrinology, 2020, Volume: 92, Issue:2

    Topics: Adrenal Cortex Function Tests; Adult; Aldosterone; Captopril; Diagnosis, Differential; Drug Administ

2020
Effects of Sodium Reduction on Energy, Metabolism, Weight, Thirst, and Urine Volume: Results From the DASH (Dietary Approaches to Stop Hypertension)-Sodium Trial.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 75, Issue:3

    Topics: Adult; Aldosterone; Basal Metabolism; Blood Pressure; Body Weight; Cross-Over Studies; Diet, Sodium-

2020
Effects of dapagliflozin on renin-angiotensin-aldosterone system under renin-angiotensin system inhibitor administration.
    Endocrine journal, 2020, Nov-28, Volume: 67, Issue:11

    Topics: Aged; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzh

2020
Clinical outcomes of laparoscopic-based renal denervation plus adrenalectomy vs adrenalectomy alone for treating resistant hypertension caused by unilateral aldosterone-producing adenoma.
    Journal of clinical hypertension (Greenwich, Conn.), 2020, Volume: 22, Issue:9

    Topics: Adenoma; Adrenalectomy; Aldosterone; Blood Pressure; Denervation; Humans; Hypertension; Kidney; Lapa

2020
Thirty-six-month results of laparoscopic-based renal denervation plus unilateral laparoscopic adrenalectomy for the treatment of patients with resistant hypertension caused by unilateral aldosterone-producing adenoma.
    Journal of clinical hypertension (Greenwich, Conn.), 2021, Volume: 23, Issue:5

    Topics: Adenoma; Adrenalectomy; Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hypertension;

2021
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021, 05-01, Volume: 97 Suppl 2

    Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome

2021
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021, 05-01, Volume: 97 Suppl 2

    Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome

2021
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021, 05-01, Volume: 97 Suppl 2

    Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome

2021
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021, 05-01, Volume: 97 Suppl 2

    Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome

2021
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021, 05-01, Volume: 97 Suppl 2

    Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome

2021
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021, 05-01, Volume: 97 Suppl 2

    Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome

2021
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021, 05-01, Volume: 97 Suppl 2

    Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome

2021
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021, 05-01, Volume: 97 Suppl 2

    Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome

2021
Superselective adrenal arterial embolization for idiopathic hyperaldosteronism: 12-month results from a proof-of-principle trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021, 05-01, Volume: 97 Suppl 2

    Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Treatment Outcome

2021
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
    Pharmacogenetics and genomics, 2021, 06-01, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi

2021
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
    Pharmacogenetics and genomics, 2021, 06-01, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi

2021
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
    Pharmacogenetics and genomics, 2021, 06-01, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi

2021
Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
    Pharmacogenetics and genomics, 2021, 06-01, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Amlodipine; Animals; Blood Pressure; Calmodulin-Bindi

2021
Effect of Reducing Sedentary Behavior on Blood Pressure (RESET BP): Rationale, design, and methods.
    Contemporary clinical trials, 2021, Volume: 106

    Topics: Accelerometry; Adult; Aged; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; COVI

2021
Effects of Renin-Angiotensin-Aldosterone Inhibitors on Early Outcomes of Hypertensive COVID-19 Patients: A Randomized Triple-Blind Clinical Trial.
    American journal of hypertension, 2021, 11-20, Volume: 34, Issue:11

    Topics: Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors;

2021
Plasma renin and aldosterone concentrations related to endovascular ultrasound renal denervation in the RADIANCE-HTN SOLO trial.
    Journal of hypertension, 2022, 02-01, Volume: 40, Issue:2

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Denervation; Female; Humans; Hypertension; Kid

2022
Integrative Blood Pressure Response to Upright Tilt Post Renal Denervation.
    American journal of hypertension, 2017, Jun-01, Volume: 30, Issue:6

    Topics: Aged; Aldosterone; Antihypertensive Agents; Arterial Pressure; Biomarkers; Cardiac Output; Cross-Sec

2017
Physiological Phenotyping for Personalized Therapy of Uncontrolled Hypertension in Africa.
    American journal of hypertension, 2017, Sep-01, Volume: 30, Issue:9

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Black People; Blood Pressure; Drug Mo

2017
Dietary Sodium Modifies Serum Uric Acid Concentrations in Humans.
    American journal of hypertension, 2017, Nov-06, Volume: 30, Issue:12

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Diet; Diet, Sodium-Restricted; Female; Humans; Hypertensio

2017
The effect of treatment for sleep apnoea on determinants of blood pressure control.
    The European respiratory journal, 2017, Volume: 50, Issue:5

    Topics: Aged; Aldosterone; Blood Pressure; Catecholamines; Continuous Positive Airway Pressure; Cross-Over S

2017
Aldosterone Is Not Associated With Metabolic and Microvascular Insulin Sensitivity in Abdominally Obese Men.
    The Journal of clinical endocrinology and metabolism, 2018, 02-01, Volume: 103, Issue:2

    Topics: Adolescent; Adult; Aged; Aldosterone; Blood Glucose; Blood Pressure; Female; Humans; Hypertension; I

2018
Adrenal Vein Sampling Is the Preferred Method to Select Patients With Primary Aldosteronism for Adrenalectomy: Con Side of the Argument.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Blood

2018
Non-uniform relationship between salt status and aldosterone activity in patients with chronic kidney disease.
    Clinical science (London, England : 1979), 2018, 01-31, Volume: 132, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Cross-Over Studies; Diet, Sodium-Restricte

2018
Greater reductions in plasma aldosterone with aliskiren in hypertensive patients with higher soluble (Pro)renin receptor level.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2018, Volume: 41, Issue:6

    Topics: Aged; Aldosterone; Amides; Antihypertensive Agents; Blood Pressure; Female; Fumarates; Humans; Hyper

2018
[The correlation between the carotid artery plaque and the change of aldosterone level related indexes during captopril challenge test].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2019, Volume: 35, Issue:1

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Carotid Stenosis; Humans; Hyperten

2019
Time course of antiproteinuric effect of aliskiren in arterial hypertension associated with type 2 diabetes and microalbuminuria.
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:4

    Topics: Adult; Aged; Albumins; Albuminuria; Aldosterone; Amides; Antihypertensive Agents; Arterial Pressure;

2013
Evidence of primary aldosteronism in a predominantly female cohort of normotensive individuals: a very high odds ratio for progression into arterial hypertension.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:4

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Case-Control Studies; Cohort Studies; Dexamethasone; Diagn

2013
Effect of acute and chronic vitamin D administration on systemic renin angiotensin system in essential hypertensives and controls.
    Journal of endocrinological investigation, 2013, Volume: 36, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calci

2013
Procalcitonin and the inflammatory response to salt in essential hypertension: a randomized cross-over clinical trial.
    Journal of hypertension, 2013, Volume: 31, Issue:7

    Topics: Aldosterone; Biomarkers; Calcitonin; Calcitonin Gene-Related Peptide; Cross-Over Studies; Humans; Hy

2013
Effect of aldosterone breakthrough on albuminuria during treatment with a direct renin inhibitor and combined effect with a mineralocorticoid receptor antagonist.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2013, Volume: 36, Issue:10

    Topics: Aged; Albuminuria; Aldosterone; Amides; Blood Pressure; Dose-Response Relationship, Drug; Drug Thera

2013
A randomised controlled trial evaluating the effect of potassium supplementation on vascular function and the renin-angiotensin-aldosterone system.
    Journal of human hypertension, 2014, Volume: 28, Issue:5

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Cross-Over Studies; Double-Blind Method; Endothelium, Vasc

2014
Long-term effects of irbesartan on plasma aldosterone concentration and left atrial volume in hypertensive patients.
    Journal of cardiology, 2014, Volume: 63, Issue:3

    Topics: Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Atrial Remodeling; Biphenyl

2014
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Aldosterone synthase inhibition for the treatment of hypertension and the derived mechanistic requirements for a new therapeutic strategy.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pre

2013
Low dose spironolactone reduces blood pressure in patients with resistant hypertension and type 2 diabetes mellitus: a double blind randomized clinical trial.
    Journal of hypertension, 2013, Volume: 31, Issue:10

    Topics: Adult; Aged; Albumins; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitori

2013
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel

2014
Effects of aliskiren on blood pressure and humoral factors in hypertensive hemodialysis patients previously on angiotensin II receptor antagonists.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:7

    Topics: Adult; Aged; Aldosterone; Amides; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents;

2014
Marinobufagenin in essential hypertension and primary aldosteronism: a cardiotonic steroid with clinical and diagnostic implications.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:2

    Topics: Aldosterone; Blood Pressure; Bufanolides; Carotid Intima-Media Thickness; Essential Hypertension; Fe

2015
A randomized controlled study of CPAP effect on plasma aldosterone concentration in patients with resistant hypertension and obstructive sleep apnea.
    Journal of hypertension, 2014, Volume: 32, Issue:8

    Topics: Aged; Aldosterone; Blood Pressure; Continuous Positive Airway Pressure; Drug Resistance; Female; Hum

2014
Renin-angiotensin system phenotyping as a guidance toward personalized medicine for ACE inhibitors: can the response to ACE inhibition be predicted on the basis of plasma renin or ACE?
    Cardiovascular drugs and therapy, 2014, Volume: 28, Issue:4

    Topics: Aged; Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl

2014
Greater efficacy of aldosterone blockade and diuretic reinforcement vs. dual renin-angiotensin blockade for left ventricular mass regression in patients with resistant hypertension.
    Journal of hypertension, 2014, Volume: 32, Issue:10

    Topics: Adolescent; Adult; Aged; Aldosterone; Amiloride; Amlodipine; Angiotensin II Type 1 Receptor Blockers

2014
Effects of spironolactone on dialysis patients with refractory hypertension: a randomized controlled study.
    Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:9

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Dose-Res

2014
Aldosterone, cognitive function, and cerebral hemodynamics in hypertension and antihypertensive therapy.
    American journal of hypertension, 2015, Volume: 28, Issue:3

    Topics: Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Cerebrovascular Circulation; Cognition; Fema

2015
Effects of a contraceptive containing drospirenone and ethinylestradiol on blood pressure, metabolic profile and neurohumoral axis in hypertensive women at reproductive age.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 182

    Topics: Adult; Aldosterone; Androstenes; Antihypertensive Agents; Baroreflex; Blood Pressure; Body Mass Inde

2014
Effects of the T/L-type calcium channel blocker benidipine on albuminuria and plasma aldosterone concentration. A pilot study involving switching from L-type calcium channel blockers to benidipine.
    International heart journal, 2014, Volume: 55, Issue:6

    Topics: Aged; Albuminuria; Aldosterone; Blood Pressure; Calcium Channel Blockers; Creatinine; Dihydropyridin

2014
Inappropriately elevated endothelin-1 plays a role in the pathogenesis of intradialytic hypertension.
    Hemodialysis international. International Symposium on Home Hemodialysis, 2015, Volume: 19, Issue:2

    Topics: Adrenomedullin; Adult; Aged; Aldosterone; Angiotensin II; Endothelin-1; Female; Humans; Hypertension

2015
Impact of baroreflex activation therapy on renal function--a pilot study.
    American journal of nephrology, 2014, Volume: 40, Issue:4

    Topics: Aged; Aldosterone; Baroreflex; Blood Pressure; Female; Glomerular Filtration Rate; Humans; Hypertens

2014
Angiotensin blockade in late autosomal dominant polycystic kidney disease.
    The New England journal of medicine, 2014, Dec-11, Volume: 371, Issue:24

    Topics: Adolescent; Adult; Albuminuria; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Co

2014
Respective effects of OSA treatment and angiotensin receptor blocker on aldosterone in hypertensive OSA patients: a randomized cross-over controlled trial.
    International journal of cardiology, 2014, Dec-15, Volume: 177, Issue:2

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Biomarkers; Cross-Over Studies; Female; Humans; Hyper

2014
TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.
    Journal of hypertension, 2015, Volume: 33, Issue:6

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Case-Control Studies; Dioxygenase

2015
Blood pressure-lowering effect of the sodium glucose co-transporter-2 inhibitor ertugliflozin, assessed via ambulatory blood pressure monitoring in patients with type 2 diabetes and hypertension.
    Diabetes, obesity & metabolism, 2015, Volume: 17, Issue:8

    Topics: Aldosterone; Antihypertensive Agents; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambu

2015
Correlations of plasma renin activity and aldosterone concentration with ambulatory blood pressure responses to nebivolol and valsartan, alone and in combination, in hypertension.
    Journal of the American Society of Hypertension : JASH, 2015, Volume: 9, Issue:11

    Topics: Aldosterone; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Double-Blind M

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Adult; Aldosterone; Animals; Diabetes Mellitus; Diet, Sodium-Restricted; Female; Hum

2015
Effects of potassium supplementation on markers of osmoregulation and volume regulation: results of a fully controlled dietary intervention study.
    Journal of hypertension, 2016, Volume: 34, Issue:2

    Topics: Aged; Aldosterone; Biomarkers; Blood Pressure; Diet, Sodium-Restricted; Dietary Supplements; Double-

2016
Low Response of Renin-Angiotensin System to Sodium Intake Intervention in Chinese Hypertensive Patients.
    Medicine, 2016, Volume: 95, Issue:6

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Biomarkers; Blood Pressure Determination; China; Diet, Sod

2016
Changeover Trial of Azilsartan and Olmesartan Comparing Effects on the Renin-Angiotensin-Aldosterone System in Patients with Essential Hypertension after Cardiac Surgery (CHAOS Study).
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2016, Jun-20, Volume: 22, Issue:3

    Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents;

2016
Effects of Vitamin D Supplementation on Plasma Aldosterone and Renin-A Randomized Placebo-Controlled Trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2016, Volume: 18, Issue:7

    Topics: Aged; Aldosterone; Dietary Supplements; Double-Blind Method; Female; Humans; Hypertension; Male; Mid

2016
Relationship Between Obesity, Hypertension, and Aldosterone Production in Postmenopausal African American Women: A Pilot Study.
    Journal of clinical hypertension (Greenwich, Conn.), 2016, Volume: 18, Issue:12

    Topics: Adipocytes; Aged; Aldosterone; Benzimidazoles; Black or African American; Cell Line; Culture Media,

2016
Treatment with patiromer decreases aldosterone in patients with chronic kidney disease and hyperkalemia on renin-angiotensin system inhibitors.
    Kidney international, 2016, Volume: 90, Issue:3

    Topics: Aged; Albuminuria; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzy

2016
Neuroendocrine and Inflammatory Responses to Losartan and Continuous Positive Airway Pressure in Patients with Hypertension and Obstructive Sleep Apnea. A Randomized Controlled Trial.
    Annals of the American Thoracic Society, 2016, Volume: 13, Issue:11

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Case-Control Studies; Continuous Positive Airw

2016
Effects of continuous positive airway pressure treatment on aldosterone excretion in patients with obstructive sleep apnoea and resistant hypertension: a randomized controlled trial.
    Journal of hypertension, 2017, Volume: 35, Issue:4

    Topics: Aged; Aldosterone; Continuous Positive Airway Pressure; Coronary Vasospasm; Diuretics; Female; Follo

2017
Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin.
    Pflugers Archiv : European journal of physiology, 2017, Volume: 469, Issue:5-6

    Topics: Adult; Aged; Albuminuria; Aldosterone; Animals; Antihypertensive Agents; Diabetic Nephropathies; Fem

2017
Development of hypertension and effects of benazepril hydrochloride in a canine remnant kidney model of chronic renal failure.
    The Journal of veterinary medical science, 2008, Volume: 70, Issue:5

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Benzazepines; Blood Pr

2008
The ovarian cycle as a factor of variability in the laboratory screening for primary aldosteronism in women.
    Journal of human hypertension, 2009, Volume: 23, Issue:2

    Topics: Adult; Aldosterone; Cohort Studies; False Positive Reactions; Female; Gonadal Steroid Hormones; Huma

2009
Intravenous intralipid-induced blood pressure elevation and endothelial dysfunction in obese African-Americans with type 2 diabetes.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:2

    Topics: Adult; Aldosterone; Black or African American; Blood Pressure; C-Reactive Protein; Diabetes Mellitus

2009
Differential effects of chlorthalidone versus spironolactone on muscle sympathetic nerve activity in hypertensive patients.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:4

    Topics: Aldosterone; Analysis of Variance; Blood Pressure; Chlorthalidone; Cross-Over Studies; Diuretics; He

2009
A reverse postural test as a screening tool for aldosterone-producing adenoma: a pilot study.
    Endocrine, 2009, Volume: 36, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Diagnosis, Differential; Exercise; Female; Hum

2009
Low-Sodium DASH reduces oxidative stress and improves vascular function in salt-sensitive humans.
    Journal of human hypertension, 2009, Volume: 23, Issue:12

    Topics: Adult; Aldosterone; Aorta; Blood Pressure; Cardiac Output; Diet, Sodium-Restricted; Elasticity; Elec

2009
Long-term effect of efonidipine therapy on plasma aldosterone and left ventricular mass index in patients with essential hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:8

    Topics: Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzym

2009
Aldosterone excess or escape: Treating resistant hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2009, Volume: 11, Issue:5

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Bloo

2009
Effects of ARB or ACE-inhibitor administration on plasma levels of aldosterone and adiponectin in hypertension.
    International heart journal, 2009, Volume: 50, Issue:4

    Topics: Adiponectin; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin II Type 1 Receptor Blockers; A

2009
Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:3

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Mass Index; Creatinine; Cross-Over Studies; Diet, Sod

2009
Protective effects of efonidipine, a T- and L-type calcium channel blocker, on renal function and arterial stiffness in type 2 diabetic patients with hypertension and nephropathy.
    Journal of atherosclerosis and thrombosis, 2009, Volume: 16, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Aldosterone; Amlodipine; Arteries; Calcium Channel Blockers; Calc

2009
Effects of angiotensin-converting enzyme inhibition on plasma aldosterone concentration, plasma renin activity, and blood pressure in spontaneously hypertensive cats with chronic renal disease.
    Veterinary therapeutics : research in applied veterinary medicine, 2002,Summer, Volume: 3, Issue:2

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Press

2002
Safety and benefits of a tablet combining losartan and hydrochlorothiazide in Japanese diabetic patients with hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:12

    Topics: Adult; Albuminuria; Aldosterone; Antihypertensive Agents; Asian People; Blood Pressure; Cross-Over S

2009
Time-dependent effects of low-dose aspirin on plasma renin activity, aldosterone, cortisol, and catecholamines.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:5

    Topics: Aged; Aldosterone; Aspirin; Catecholamines; Circadian Rhythm; Cross-Over Studies; Dose-Response Rela

2009
Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Conve

2010
Racial differences in potassium homeostasis in response to differences in dietary sodium in girls.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:3

    Topics: Adolescent; Aldosterone; Analysis of Variance; Black or African American; Blood Pressure; Body Weigh

2010
Racial differences in potassium homeostasis in response to differences in dietary sodium in girls.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:3

    Topics: Adolescent; Aldosterone; Analysis of Variance; Black or African American; Blood Pressure; Body Weigh

2010
Racial differences in potassium homeostasis in response to differences in dietary sodium in girls.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:3

    Topics: Adolescent; Aldosterone; Analysis of Variance; Black or African American; Blood Pressure; Body Weigh

2010
Racial differences in potassium homeostasis in response to differences in dietary sodium in girls.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:3

    Topics: Adolescent; Aldosterone; Analysis of Variance; Black or African American; Blood Pressure; Body Weigh

2010
Does the ratio of serum aldosterone to plasma renin activity predict the efficacy of diuretics in hypertension? Results of RENALDO.
    Journal of hypertension, 2010, Volume: 28, Issue:1

    Topics: Aldosterone; Bendroflumethiazide; Blood Pressure; Cross-Over Studies; Diuretics; Drug Therapy, Combi

2010
Effect of body weight loss and normalization on blood pressure in overweight non-obese patients with stage 1 hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:3

    Topics: Aged; Aldosterone; Blood Glucose; Blood Pressure; Body Mass Index; Diet, Reducing; Female; Humans; H

2010
Diagnosis of primary aldosteronism: comparison of post-captopril active renin concentration and plasma renin activity.
    Clinica chimica acta; international journal of clinical chemistry, 2010, May-02, Volume: 411, Issue:9-10

    Topics: Adult; Aged; Aldosterone; Area Under Curve; Captopril; Diagnosis, Differential; Female; Humans; Hype

2010
Impact of different diagnostic criteria during adrenal vein sampling on reproducibility of subtype diagnosis in patients with primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Aldosterone; Cath

2010
Impact of different diagnostic criteria during adrenal vein sampling on reproducibility of subtype diagnosis in patients with primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Aldosterone; Cath

2010
Impact of different diagnostic criteria during adrenal vein sampling on reproducibility of subtype diagnosis in patients with primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Aldosterone; Cath

2010
Impact of different diagnostic criteria during adrenal vein sampling on reproducibility of subtype diagnosis in patients with primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Aldosterone; Cath

2010
Effects of eprosartan on diastolic function and neurohormones in patients with hypertension and diastolic dysfunction.
    Cardiovascular drugs and therapy, 2010, Volume: 24, Issue:1

    Topics: Acrylates; Aged; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Bloo

2010
[Does spironolactone use at arterial hypertension therapy protect endothelium also in smoking patients?].
    Przeglad lekarski, 2009, Volume: 66, Issue:10

    Topics: Aldosterone; Diuretics; Endothelin-1; Endothelium, Vascular; Female; Humans; Hypertension; Male; Mid

2009
Impact of aldosterone receptor blockade compared with thiazide therapy on sympathetic nervous system function in geriatric hypertension.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:5

    Topics: Aged; Aldosterone; Blood Pressure; Body Composition; Catecholamines; Diuretics; Female; Heart Rate;

2010
Beta2-adrenergic receptor genotype affects the renin-angiotensin-aldosterone system response to the Dietary Approaches to Stop Hypertension (DASH) dietary pattern.
    The American journal of clinical nutrition, 2010, Volume: 92, Issue:2

    Topics: Aldosterone; Alleles; Blood Pressure; Diet; Female; Genotype; Humans; Hypertension; Male; Middle Age

2010
Effect of modest salt reduction on skin capillary rarefaction in white, black, and Asian individuals with mild hypertension.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:2

    Topics: Adult; Aged; Aldosterone; Asian People; Black People; Capillaries; Diet, Sodium-Restricted; Double-B

2010
A new-generation N/L-type calcium channel blocker leads to less activation of the renin-angiotensin system compared with conventional L type calcium channel blocker.
    Journal of hypertension, 2010, Volume: 28, Issue:10

    Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin I; Angiotensin II; Blood Pressure; Calcium C

2010
Effects of ACE inhibitors on cardiac angiotensin II and aldosterone in humans: "Relevance of lipophilicity and affinity for ACE".
    American journal of hypertension, 2010, Volume: 23, Issue:11

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Aorta, Thoracic;

2010
Simvastatin reduces sympathetic activity in men with hypertension and hypercholesterolemia.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:10

    Topics: Adult; Aldosterone; Anticholesteremic Agents; Blood Pressure; Catecholamines; Comorbidity; Double-Bl

2010
Role of plasma aldosterone concentration in regression of left-ventricular mass following antihypertensive medication.
    Journal of hypertension, 2011, Volume: 29, Issue:2

    Topics: Adult; Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agen

2011
Benidipine reduces albuminuria and plasma aldosterone in mild-to-moderate stage chronic kidney disease with albuminuria.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:2

    Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calciu

2011
Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin.
    Trials, 2011, Jan-14, Volume: 12

    Topics: Adult; Aldosterone; Androstanols; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Protei

2011
Additive antioxidative effects of azelnidipine on angiotensin receptor blocker olmesartan treatment for type 2 diabetic patients with albuminuria.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:8

    Topics: Aged; Albuminuria; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Azetidinecarboxylic Acid; B

2011
Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertension.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2011, Volume: 12, Issue:4

    Topics: Aldosterone; Amides; Antihypertensive Agents; Blood Pressure; Demography; Female; Fumarates; Heart V

2011
Tagging SNPs in REN, AGTR1 and AGTR2 genes and response of renin activity, angiotensin II and aldosterone concentrations to antihypertensive treatment in Kazakans.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2011, Volume: 12, Issue:4

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aten

2011
Effects of olmesartan on the renin-angiotensin-aldosterone system for patients with essential hypertension after cardiac surgery--investigation using a candesartan change-over study.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2011, Volume: 17, Issue:5

    Topics: Aged; Aldosterone; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; An

2011
Olmesartan medoxomil treatment is associated with decreased plasma B-type natriuretic peptide levels in patients on hemodialysis.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:2

    Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Female; Humans; Hyper

2012
Effects of a novel aldosterone synthase inhibitor for treatment of primary hypertension: results of a randomized, double-blind, placebo- and active-controlled phase 2 trial.
    Circulation, 2011, Nov-01, Volume: 124, Issue:18

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Cytochrome

2011
Abnormal increase in urinary aquaporin-2 excretion in response to hypertonic saline in essential hypertension.
    BMC nephrology, 2012, Mar-27, Volume: 13

    Topics: Adult; Aldosterone; Angiotensin II; Aquaporin 2; Atrial Natriuretic Factor; Cross-Over Studies; Cycl

2012
Efficacy analysis of the renoprotective effects of aliskiren in hypertensive patients with chronic kidney disease.
    Heart and vessels, 2013, Volume: 28, Issue:4

    Topics: Aged; Albuminuria; Aldosterone; Amides; Antihypertensive Agents; Biomarkers; Blood Pressure; Diabeti

2013
Association between postexercise hypotension and long-term training-induced blood pressure reduction: a pilot study.
    Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 2013, Volume: 23, Issue:1

    Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Decision Support Techniques; Exercise Test; Exercise

2013
Adrenalectomy reverses myocardial fibrosis in patients with primary aldosteronism.
    Journal of hypertension, 2012, Volume: 30, Issue:8

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Cardiomyopathies; Echocardiography; Fe

2012
Hypertensive left ventricular hypertrophy: a mechanistic approach to optimizing regression assessed by cardiovascular magnetic resonance.
    Journal of hypertension, 2012, Volume: 30, Issue:10

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Female; Humans; Hypertension; Hypertrophy, Left V

2012
L/N-type calcium channel blocker cilnidipine reduces plasma aldosterone, albuminuria, and urinary liver-type fatty acid binding protein in patients with chronic kidney disease.
    Heart and vessels, 2013, Volume: 28, Issue:4

    Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensiv

2013
The effects of aldosterone synthase inhibition on aldosterone and cortisol in patients with hypertension: a phase II, randomized, double-blind, placebo-controlled, multicenter study.
    Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:9

    Topics: Adolescent; Adult; Aged; Aldosterone; Arterial Pressure; Cytochrome P-450 CYP11B2; Double-Blind Meth

2012
Effect of amiloride and spironolactone on renal tubular function and central blood pressure in patients with arterial hypertension during baseline conditions and after furosemide: a double-blinded, randomized, placebo-controlled crossover trial.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2013, Volume: 35, Issue:5

    Topics: Aged; Aldosterone; Amiloride; Angiotensin II; Aquaporin 2; Blood Pressure; Cross-Over Studies; Diure

2013
Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:5

    Topics: Adult; Aldosterone; Blood Pressure; Body Mass Index; Diet; Dose-Response Relationship, Drug; Female;

2012
Angiotensin II, independent of plasma renin activity, contributes to the hypertension of autonomic failure.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:3

    Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents;

2013
Vasoactive modulators during and after craniotomy: relation to postoperative hypertension.
    Journal of neurosurgical anesthesiology, 2002, Volume: 14, Issue:3

    Topics: Adult; Aged; Aldosterone; Anesthesia; Atrial Natriuretic Factor; Blood Pressure; Catecholamines; Cra

2002
Vasoactive modulators during and after craniotomy: relation to postoperative hypertension.
    Journal of neurosurgical anesthesiology, 2002, Volume: 14, Issue:3

    Topics: Adult; Aged; Aldosterone; Anesthesia; Atrial Natriuretic Factor; Blood Pressure; Catecholamines; Cra

2002
Vasoactive modulators during and after craniotomy: relation to postoperative hypertension.
    Journal of neurosurgical anesthesiology, 2002, Volume: 14, Issue:3

    Topics: Adult; Aged; Aldosterone; Anesthesia; Atrial Natriuretic Factor; Blood Pressure; Catecholamines; Cra

2002
Vasoactive modulators during and after craniotomy: relation to postoperative hypertension.
    Journal of neurosurgical anesthesiology, 2002, Volume: 14, Issue:3

    Topics: Adult; Aged; Aldosterone; Anesthesia; Atrial Natriuretic Factor; Blood Pressure; Catecholamines; Cra

2002
Additive effect of drospirenone/17-beta-estradiol in hypertensive postmenopausal women receiving enalapril.
    American journal of hypertension, 2002, Volume: 15, Issue:9

    Topics: Aldosterone; Androstenes; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Double-Bli

2002
Influence of AT1 receptor blockade on blood pressure, renal haemodynamics and hormonal responses to intravenous angiotensin II infusion in hypertensive patients.
    Blood pressure, 2002, Volume: 11, Issue:4

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl

2002
Effect of spironolactone on impaired fibrinolysis of hypertensive patients.
    Kidney & blood pressure research, 2002, Volume: 25, Issue:4

    Topics: Adult; Aged; Aldosterone; Female; Fibrinolysis; Humans; Hypertension; Male; Middle Aged; Mineralocor

2002
Hyperaldosteronism among black and white subjects with resistant hypertension.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug

2002
Hyperaldosteronism among black and white subjects with resistant hypertension.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug

2002
Hyperaldosteronism among black and white subjects with resistant hypertension.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug

2002
Hyperaldosteronism among black and white subjects with resistant hypertension.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug

2002
Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Aldosterone; Amlodipine; Antihypertensive Agents; Atenolol; Biphenyl Compounds; Confounding Factors,

2002
Racial difference in the activity of the amiloride-sensitive epithelial sodium channel.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Amiloride; Black People; Blood Pressure; Body Mass Index; Cohort Stu

2002
Efficacy and tolerability of eplerenone and losartan in hypertensive black and white patients.
    Journal of the American College of Cardiology, 2003, Apr-02, Volume: 41, Issue:7

    Topics: Adult; Aldosterone; Analysis of Variance; Angiotensin Receptor Antagonists; Antihypertensive Agents;

2003
Plasma fatty acids response to central volume expansion in salt-sensitive hypertension.
    Metabolism: clinical and experimental, 2003, Volume: 52, Issue:4

    Topics: Adult; Aldosterone; Blood Volume; Creatinine; Fatty Acids, Nonesterified; Female; Humans; Hypertensi

2003
Effect of amlodipine, quinapril, and losartan on pulse wave velocity and plasma collagen markers in patients with mild-to-moderate arterial hypertension.
    American journal of hypertension, 2003, Volume: 16, Issue:6

    Topics: Adult; Aldosterone; Amlodipine; Antihypertensive Agents; Biomarkers; Blood Flow Velocity; Blood Pres

2003
Assessment of the novel selective aldosterone blocker eplerenone using ambulatory and clinical blood pressure in patients with systemic hypertension.
    The American journal of cardiology, 2003, Jul-01, Volume: 92, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Eplerenone; Female; Heart

2003
One year follow-up of hormone replacement therapy with percutaneous estradiol and low-dose vaginal natural progesterone in women with mild to moderate hypertension.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2003, Volume: 111, Issue:5

    Topics: Administration, Cutaneous; Administration, Intravaginal; Aldosterone; Amlodipine; Antihypertensive A

2003
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
    American journal of hypertension, 2003, Volume: 16, Issue:11 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens

2003
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
    American journal of hypertension, 2003, Volume: 16, Issue:11 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens

2003
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
    American journal of hypertension, 2003, Volume: 16, Issue:11 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens

2003
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
    American journal of hypertension, 2003, Volume: 16, Issue:11 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens

2003
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
    American journal of hypertension, 2003, Volume: 16, Issue:11 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens

2003
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
    American journal of hypertension, 2003, Volume: 16, Issue:11 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens

2003
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
    American journal of hypertension, 2003, Volume: 16, Issue:11 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens

2003
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
    American journal of hypertension, 2003, Volume: 16, Issue:11 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens

2003
Efficacy of low-dose spironolactone in subjects with resistant hypertension.
    American journal of hypertension, 2003, Volume: 16, Issue:11 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertens

2003
Synthetic human alpha-atrial natriuretic peptide improves the management of postoperative hypertension and renal dysfunction after the repair of abdominal aortic aneurysm.
    Journal of cardiovascular pharmacology, 2003, Volume: 42, Issue:5

    Topics: Aged; Aldosterone; Aortic Aneurysm, Abdominal; Atrial Natriuretic Factor; Chi-Square Distribution; F

2003
Acute angiotensin II increases plasma F2-isoprostanes in salt-replete human hypertensives.
    Free radical biology & medicine, 2003, Oct-01, Volume: 35, Issue:7

    Topics: Adult; Aldosterone; Angiotensin II; Biomarkers; Blood Pressure; Drug Interactions; F2-Isoprostanes;

2003
Effect of an angiotensin II type 1 receptor blocker, valsartan, on neurohumoral factors in patients with hypertension: comparison with a long-acting calcium channel antagonist, amlodipine.
    Journal of cardiovascular pharmacology, 2003, Volume: 42 Suppl 1

    Topics: Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Co

2003
Hemodynamic effects of amlodipine, bisoprolol, and lisinopril in hypertensive patients after liver transplantation.
    Transplantation, 2004, Mar-15, Volume: 77, Issue:5

    Topics: Adult; Aged; Aldosterone; Amlodipine; Antihypertensive Agents; Bisoprolol; Cross-Over Studies; Femal

2004
Randomized double-blind placebo-controlled study of an angiotensin immunotherapeutic vaccine (PMD3117) in hypertensive subjects.
    Clinical science (London, England : 1979), 2004, Volume: 107, Issue:2

    Topics: Adolescent; Adult; Aged; Aldosterone; Aluminum Hydroxide; Angiotensin I; Angiotensin-Converting Enzy

2004
Active renin versus plasma renin activity to define aldosterone-to-renin ratio for primary aldosteronism.
    Journal of hypertension, 2004, Volume: 22, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Differential Threshold; Female; Humans;

2004
Genetic factors associated with volume-sensitive hypertension.
    Molecular and cellular endocrinology, 2004, Mar-31, Volume: 217, Issue:1-2

    Topics: Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Blood Volume; Calmodulin-Binding Proteins

2004
Influence of dietary sodium on the renin-angiotensin-aldosterone system and prevalence of left ventricular hypertrophy by EKG criteria.
    Journal of human hypertension, 2005, Volume: 19, Issue:2

    Topics: Aldosterone; Blood Pressure; Electrocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ve

2005
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
    Clinical chemistry, 2005, Volume: 51, Issue:2

    Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2005
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
    Clinical chemistry, 2005, Volume: 51, Issue:2

    Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2005
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
    Clinical chemistry, 2005, Volume: 51, Issue:2

    Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2005
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
    Clinical chemistry, 2005, Volume: 51, Issue:2

    Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2005
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
    Clinical chemistry, 2005, Volume: 51, Issue:2

    Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2005
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
    Clinical chemistry, 2005, Volume: 51, Issue:2

    Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2005
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
    Clinical chemistry, 2005, Volume: 51, Issue:2

    Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2005
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
    Clinical chemistry, 2005, Volume: 51, Issue:2

    Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2005
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
    Clinical chemistry, 2005, Volume: 51, Issue:2

    Topics: Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2005
Aldosterone-to-renin ratio, arterial stiffness, and the response to aldosterone antagonism in essential hypertension.
    American journal of hypertension, 2005, Volume: 18, Issue:1

    Topics: Aldosterone; Arteries; Bendroflumethiazide; Blood Flow Velocity; Blood Pressure; Compliance; Cross-O

2005
Effects of circadian rhythms, posture, and medication on renin-aldosterone interrelations in essential hypertensives.
    American journal of hypertension, 2005, Volume: 18, Issue:1

    Topics: Adult; Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Convertin

2005
Mechanisms of hypertension after liver transplantation.
    Transplantation, 2005, Apr-27, Volume: 79, Issue:8

    Topics: Adult; Aged; Aldosterone; Endothelin-1; Female; Humans; Hypertension; Liver Transplantation; Male; M

2005
Effect of spironolactone on blood pressure and the renin-angiotensin-aldosterone system in oligo-anuric hemodialysis patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:1

    Topics: Adult; Aldosterone; Antihypertensive Agents; Anuria; Blood Pressure; Body Weight; Cross-Over Studies

2005
Endogenous ouabain and acute salt loading in low-renin hypertension.
    American journal of hypertension, 2005, Volume: 18, Issue:7

    Topics: Adrenocorticotropic Hormone; Aldosterone; Biomarkers; Blood Pressure; Cardenolides; Female; Hormones

2005
Effects of dual blockade of the renin angiotensin system in hypertensive type 2 diabetic patients with nephropathy.
    Clinical nephrology, 2005, Volume: 64, Issue:3

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Conve

2005
Central role for ENaC in development of hypertension.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:11

    Topics: Aldosterone; Amiloride; Antihypertensive Agents; Blood Pressure; Epithelial Sodium Channels; Humans;

2005
Effects of a new hormone therapy, drospirenone and 17-beta-estradiol, in postmenopausal women with hypertension.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 48, Issue:2

    Topics: Aged; Aldosterone; Androstenes; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cholesterol;

2006
Dual blockade of angiotensin II with enalapril and losartan reduces proteinuria in hypertensive patients with type 2 diabetes.
    Endocrine journal, 2006, Volume: 53, Issue:4

    Topics: Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents

2006
Effects of spironolactone during an angiotensin II receptor blocker treatment on the left ventricular mass reduction in hypertensive patients with concentric left ventricular hypertrophy.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:8

    Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl

2006
Can the blood pressure effects of COX-2 selective inhibitors be explained by changes in plasma aldosterone levels?
    Journal of hypertension, 2006, Volume: 24, Issue:10

    Topics: Aged; Aldosterone; Blood Pressure; Celecoxib; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Femal

2006
Bovine casein hydrolysate (c12 Peptide) reduces blood pressure in prehypertensive subjects.
    American journal of hypertension, 2007, Volume: 20, Issue:1

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Case

2007
Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study.
    BMC cardiovascular disorders, 2007, May-09, Volume: 7

    Topics: Aldosterone; Bendroflumethiazide; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Ren

2007
Prospective evaluation of the saline infusion test for excluding primary aldosteronism due to aldosterone-producing adenoma.
    Journal of hypertension, 2007, Volume: 25, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hydrocortisone; Hype

2007
Prospective evaluation of the saline infusion test for excluding primary aldosteronism due to aldosterone-producing adenoma.
    Journal of hypertension, 2007, Volume: 25, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hydrocortisone; Hype

2007
Prospective evaluation of the saline infusion test for excluding primary aldosteronism due to aldosterone-producing adenoma.
    Journal of hypertension, 2007, Volume: 25, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hydrocortisone; Hype

2007
Prospective evaluation of the saline infusion test for excluding primary aldosteronism due to aldosterone-producing adenoma.
    Journal of hypertension, 2007, Volume: 25, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hydrocortisone; Hype

2007
The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio.
    Circulation, 2007, Jul-17, Volume: 116, Issue:3

    Topics: Aged; Aldosterone; Amiloride; Bendroflumethiazide; Cross-Over Studies; Double-Blind Method; Female;

2007
Gradual reactivation of vascular angiotensin I to angiotensin II conversion during chronic ACE inhibitor therapy in patients with diabetes mellitus.
    Diabetologia, 2007, Volume: 50, Issue:10

    Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; B

2007
Pharmacokinetics and pharmacodynamics of drospirenone-estradiol combination hormone therapy product coadministered with hydrochlorothiazide in hypertensive postmenopausal women.
    Journal of clinical pharmacology, 2007, Volume: 47, Issue:10

    Topics: Aged; Aldosterone; Androstenes; Antihypertensive Agents; Area Under Curve; Biological Availability;

2007
Comparison of the effects of efonidipine and amlodipine on aldosterone in patients with hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:8

    Topics: Aged; Aged, 80 and over; Aldosterone; Amlodipine; Blood Pressure; Calcium Channel Blockers; Calcium

2007
Aldosterone escape with diuretic or angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker combination therapy in patients with mild to moderate hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:10

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biph

2007
Aldosterone breakthrough during angiotensin II receptor blockade in hypertensive patients with diabetes mellitus.
    American journal of hypertension, 2007, Volume: 20, Issue:12

    Topics: Aged; Albuminuria; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Co

2007
Spironolactone for poorly controlled hypertension in type 2 diabetes: conflicting effects on blood pressure, endothelial function, glycaemic control and hormonal profiles.
    Diabetologia, 2008, Volume: 51, Issue:5

    Topics: Aged; Aldosterone; Angiotensin II; Blood Glucose; Blood Pressure; Body Mass Index; Cross-Over Studie

2008
Enalapril and atenolol in primary hypertension--a comparative study of blood pressure lowering and hormonal effects.
    Scandinavian journal of urology and nephrology. Supplementum, 1984, Volume: 79

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolo

1984
Effect of dietary sodium on angiotensin-converting enzyme (ACE) inhibition and the acute hypotensive effect of enalapril (MK-421) in essential hypertension.
    Journal of hypertension, 1984, Volume: 2, Issue:4

    Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; B

1984
Long-term clinical experience with enalapril in essential hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1983, Volume: 1, Issue:1

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Therapy, Combina

1983
Blood pressure and hormonal changes following alteration in dietary sodium and potassium in mild essential hypertension.
    Lancet (London, England), 1981, Jan-10, Volume: 1, Issue:8211

    Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Diet, Sodium-Restricted; Double-Blind

1981
Blood pressure and hormonal changes following alteration in dietary sodium and potassium in young men with and without a familial predisposition to hypertension.
    Lancet (London, England), 1981, Jan-17, Volume: 1, Issue:8212

    Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Diet; Hormones; Humans; Hypertension;

1981
Lack of beta-adrenoreceptor hypersensitivity after abrupt withdrawal of long-term therapy with oxprenolol.
    Circulation, 1981, Volume: 64, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Delayed-Action Preparations; Drug Hypersensitivity;

1981
Acute effects of prizidilol on blood pressure, heart rate, catecholamines, renin and aldosterone in essential hypertension.
    European journal of clinical pharmacology, 1982, Volume: 23, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Female; Heart

1982
Antihypertensive effects of bunitrolol in essential hypertension.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:8

    Topics: Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Mid

1983
Single-agent and combination therapy of essential hypertension.
    American heart journal, 1984, Volume: 108, Issue:2

    Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Diuretics; Drug Therapy

1984
Bucindolol, a beta-adrenoceptor blocker with vasodilatory action: its effect in systemic hypertension.
    The American journal of cardiology, 1984, Aug-01, Volume: 54, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Drug Therapy, Combination; Female;

1984
Antihypertensive and humoral effects of verapamil and nifedipine in essential hypertension.
    Journal of cardiovascular pharmacology, 1982, Volume: 4 Suppl 3

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Volume; Calcium Channel Blockers;

1982
The relation between cardiac hypertrophy and hypertension.
    Acta medica Scandinavica. Supplementum, 1983, Volume: 672

    Topics: Aldosterone; Blood Glucose; Blood Pressure; Cardiomegaly; Heart Ventricles; Humans; Hypertension; In

1983
[A new principle in long-term treatment of essential hypertension: angiotensin-converting enzyme inhibition (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Apr-11, Volume: 105, Issue:15

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captop

1980
Uncontrollable hypertension in patients on hemodialysis: long-term treatment with captopril and salt subtraction.
    Clinical nephrology, 1981, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Captopril; Child; Clinical Trials as Topic; Female; Humans; Hyperten

1981
Fluctuations in the plasma angiotensin I converting enzyme activity during long-term treatment with captopril.
    Acta cardiologica, 1982, Volume: 37, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; M

1982
Low-dose captopril: its use in mild to moderate hypertension unresponsive to diuretic treatment.
    Archives of internal medicine, 1982, Volume: 142, Issue:6

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Clini

1982
A comparative pilot study of enalapril, a new converting enzyme inhibitor, and hydrochlorothiazide in essential hypertension.
    Journal of clinical pharmacology, 1982, Volume: 22, Issue:7

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Dipeptides; Enal

1982
The effect of captopril and propranolol on the responses to posture and isometric exercise in patients with essential hypertension.
    European journal of clinical pharmacology, 1983, Volume: 25, Issue:6

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Fe

1983
[Clinical study of the efficacy of oral potassium canrenoate and spironolactone in essential arterial hypertension].
    Minerva medica, 1983, Apr-07, Volume: 74, Issue:14-15

    Topics: Administration, Oral; Adult; Aldosterone; Blood Pressure; Canrenoic Acid; Clinical Trials as Topic;

1983
Captopril, aldosterone and urinary kallikrein in primary hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:4

    Topics: Aldosterone; Angiotensin II; Captopril; Humans; Hydrochlorothiazide; Hypertension; Kallikreins; Prol

1983
Clinical efficacy, safety, and pharmacokinetics of indapamide in renal impairment.
    American heart journal, 1983, Volume: 106, Issue:1 Pt 2

    Topics: Aldosterone; Blood Pressure; Body Weight; Diuretics; Hemodynamics; Humans; Hypertension; Indapamide;

1983
The effects of piretanide on catecholamine metabolism, plasma renin activity and serum aldosterone: a double-blind pilot comparison against hydrochlorothiazide in patients with essential hypertension.
    Pharmatherapeutica, 1984, Volume: 3, Issue:9

    Topics: Aged; Aldosterone; Blood Pressure; Catecholamines; Diuretics; Dopamine; Double-Blind Method; Female;

1984
Effects of indomethacin, sulindac, naproxen, aspirin, and paracetamol in treated hypertensive patients.
    Clinical and experimental hypertension. Part A, Theory and practice, 1984, Volume: 6, Issue:6

    Topics: Acetaminophen; Aldosterone; Aspirin; Blood Pressure; Clinical Trials as Topic; Double-Blind Method;

1984
Efficacy of low-dose captopril given twice daily to patients with essential hypertension uncontrolled by a beta blocker plus thiazide diuretic.
    The Journal of international medical research, 1984, Volume: 12, Issue:4

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Captopril; Chlorthalidone; Dose-Response Relationship, Dru

1984
Clinical biochemical and haemodynamic correlates of sodium sensitivity in essential hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1983, Volume: 1, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Diet, Sodium-Restricted; Female; Forea

1983
Sodium sensitivity in essential hypertension: role of the renin-angiotensin-aldosterone system and predictive value of an intravenous frusemide test.
    Journal of hypertension, 1984, Volume: 2, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Diet; Female; Furosemide; Humans; Hypertension; Mal

1984
[Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension].
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:5

    Topics: Adult; Aged; Aldosterone; Calcium Channel Blockers; Electrolytes; Female; Heart Rate; Humans; Hydroc

1984
Antihypertensive and metabolic effects of increasing doses of atenolol and labetalol. A comparative study in primary hypertension.
    Acta medica Scandinavica. Supplementum, 1982, Volume: 665

    Topics: Adult; Aged; Aldosterone; Atenolol; Blood Pressure; Double-Blind Method; Drug Evaluation; Ethanolami

1982
[Controlled study of the anti-hypertensive effects of indapamide, metoprolol and their combination in patients with essential arterial hypertension].
    Cardiologia (Rome, Italy), 1982, Volume: 27, Issue:8

    Topics: Adult; Aged; Aldosterone; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Exercise T

1982
[Controlled study of antihypertensive effects of indapamide and metoprolol and their combination in patients with essential arterial hypertension].
    Cardiologia (Rome, Italy), 1982, Volume: 27, Issue:8

    Topics: Adult; Aged; Aldosterone; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; He

1982
Controlled trial of biofeedback-aided behavioural methods in reducing mild hypertension.
    British medical journal (Clinical research ed.), 1981, Jun-20, Volume: 282, Issue:6281

    Topics: Adult; Aldosterone; Biofeedback, Psychology; Cholesterol; Clinical Trials as Topic; Female; Humans;

1981
Captopril in essential hypertension; contrasting effects of adding hydrochlorothiazide or propranolol.
    British medical journal (Clinical research ed.), 1982, Mar-06, Volume: 284, Issue:6317

    Topics: Adult; Aged; Aldosterone; Body Weight; Captopril; Clinical Trials as Topic; Drug Therapy, Combinatio

1982
Reduced pressor effect of angiotensin II and of noradrenaline in normal man following the oral administration of the calcium-antagonist nifedipine.
    European journal of clinical investigation, 1982, Volume: 12, Issue:3

    Topics: Administration, Oral; Adult; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers;

1982
Response of thiazide-induced hypokalemia to amiloride.
    JAMA, 1983, Jan-14, Volume: 249, Issue:2

    Topics: Aldosterone; Amiloride; Bicarbonates; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypert

1983
Spironolactone and triamterene in volume-dependent essential hypertension.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:1

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Hum

1980
Hemodynamic changes during long-term thiazide treatment of essential hypertension in responders and nonresponders.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:3

    Topics: Adult; Aldosterone; Blood Volume; Body Weight; Diuresis; Hemodynamics; Humans; Hydrochlorothiazide;

1980
Antihypertensive effect of fractionated sublingual administration of nifedipine in moderate essential hypertension.
    European journal of clinical pharmacology, 1980, Volume: 17, Issue:3

    Topics: Administration, Oral; Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Clinical Trials a

1980
Effect of moderate salt restriction and high potassium intake on pressor hormones, response to noradrenaline and baroreceptor function in man.
    Clinical science (London, England : 1979), 1980, Volume: 59 Suppl 6

    Topics: Adult; Aldosterone; Blood Pressure; Diet; Diet, Sodium-Restricted; Heart Rate; Humans; Hypertension;

1980
Captopril, an orally active converting enzyme inhibitor, in the treatment of primary hypertension. A controlled long-term study with reference to initial plasma renin activity.
    Acta medica Scandinavica, 1981, Volume: 209, Issue:4

    Topics: Adult; Aldosterone; Captopril; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combinat

1981
The renin-aldosterone system during exercise in young patients with essential hypertension.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 646

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Male; Physical Exertion; Renin; Sodium Chloride

1981
Antihypertensive and hormonal effects of single oral doses of captopril and nifedipine in essential hypertension.
    European journal of clinical pharmacology, 1981, Volume: 20, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aldosterone; Captopril; Female; Humans; Hypertension; Male; Middl

1981
Correlation between propranolol in plasma and urine, renin-aldosterone system and blood pressure in essential hypertension.
    European journal of clinical pharmacology, 1981, Volume: 20, Issue:4

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Ma

1981
[Effect of propranolol on diuretic activity of furosemide hypertensive patients (author's transl)].
    Nephrologie, 1981, Volume: 2, Issue:4

    Topics: Aldosterone; Diuresis; Drug Synergism; Female; Furosemide; Humans; Hypertension; Male; Osmolar Conce

1981
Merits of adding a beta blocker (acebutolol) to a diuretic (hydrochlorothiazide) in the treatment of hypertension.
    Journal of clinical pharmacology, 1982, Volume: 22, Issue:1

    Topics: Acebutolol; Adult; Aldosterone; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combina

1982
Effects of once daily indapamide and pindolol on blood pressure, plasma aldosterone concentration and plasma renin activity in a general practice setting.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:3

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Diuretics; Family Practice; Heart Rate; Humans; Hypertensi

1982
Interaction between oxprenolol and indomethacin on blood pressure in essential hypertensive patients.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Interactions

1982
[Spironolactone in essential hypertension associated with abnormal aldosterone regulation and in Conn's syndrome (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, May-02, Volume: 105, Issue:18

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi

1980
Young borderline hypertensives are hyperreactive to mental arithmetic stress: spectral analysis of R-R intervals.
    Journal of the autonomic nervous system, 1995, Aug-04, Volume: 54, Issue:2

    Topics: Adult; Aging; Aldosterone; Blood Pressure; Electrocardiography; Heart Rate; Humans; Hypertension; Ma

1995
Renin-angiotensin-aldosterone system, RR interval, and blood pressure variability during postural changes in borderline arterial hypertension.
    American journal of hypertension, 1995, Volume: 8, Issue:7

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male;

1995
Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM.
    Diabetes care, 1995, Volume: 18, Issue:7

    Topics: Albuminuria; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Blood P

1995
Age is a major determinant of the divergent blood pressure responses to varying salt intake in essential hypertension.
    American journal of hypertension, 1995, Volume: 8, Issue:8

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aldosterone; Atrial Natriuretic Factor; Blood Pressure;

1995
Effects of losartan on the renin-angiotensin-aldosterone axis in essential hypertension.
    Journal of human hypertension, 1995, Volume: 9, Issue:4

    Topics: Aldosterone; Angiotensin II; Biphenyl Compounds; Blood Pressure; Creatinine; Drug Combinations; Fema

1995
Differing mechanisms of action of angiotensin-converting enzyme inhibition in black and white hypertensive patients. The Trandolapril Multicenter Study Group.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:1

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Blood

1995
Divergent effects of dihydropyridine and phenylalkylamine calcium channel antagonist classes on autonomic function in human hypertension.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:1

    Topics: Aldosterone; Analysis of Variance; Autonomic Nervous System; Baroreflex; Calcium Channel Blockers; C

1995
Normal sympathetic vasomotor and cardiac parasympathetic activities in patients with primary aldosteronism: assessment by spectral analysis.
    Journal of the autonomic nervous system, 1995, Apr-08, Volume: 52, Issue:2-3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Blood Pressure; Electroca

1995
Hormonal and renal responses to atrial natriuretic peptide infusion in low-renin hypertension.
    American journal of nephrology, 1995, Volume: 15, Issue:3

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Cross-Over Studies; Double-Blind Method; Glomerular F

1995
Comparison of moexipril, a new ACE inhibitor, to verapamil-SR as add-on therapy to low dose hydrochlorothiazide in hypertensive patients.
    American journal of hypertension, 1995, Volume: 8, Issue:4 Pt 1

    Topics: Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Delayed-Action Preparat

1995
Regulation of sodium excretion in human hypertension: long-term effects of calcium antagonist and angiotensin converting enzyme inhibitor.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:6

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Calcium Cha

1993
Hemodynamic and humoral effects of the angiotensin II antagonist losartan in essential hypertension.
    American journal of hypertension, 1994, Volume: 7, Issue:12

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bod

1994
Salt sensitive essential hypertension evaluated by 24 hour ambulatory blood pressure.
    Blood pressure, 1994, Volume: 3, Issue:6

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Blood Pressure Monitoring, Ambulatory

1994
[Potassium citrate versus potassium chloride in essential hypertension. Effects on hemodynamic, hormonal and metabolic parameters].
    Deutsche medizinische Wochenschrift (1946), 1995, May-05, Volume: 120, Issue:18

    Topics: Adult; Aged; Aldosterone; Blood Glucose; Blood Pressure; Citrates; Citric Acid; Cross-Over Studies;

1995
Coenzyme Q10 in essential hypertension.
    Molecular aspects of medicine, 1994, Volume: 15 Suppl

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Cholesterol; Cholesterol, HDL; Co

1994
Amlodipine and haemodynamic effects of cyclo-oxygenase inhibition.
    British journal of clinical pharmacology, 1995, Volume: 39, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Amlodipine; Biomarkers; Blood Pressure; Creatinine

1995
The renin angiotensin aldosterone system and frusemide response in congestive heart failure.
    British journal of clinical pharmacology, 1995, Volume: 39, Issue:1

    Topics: Administration, Oral; Aged; Aldosterone; Captopril; Cross-Over Studies; Drug Therapy, Combination; F

1995
[Endocrine effects of nicardipine on intraoperative hypertension under droperidol-fentanyl-ketamine (DFK) anesthesia].
    Masui. The Japanese journal of anesthesiology, 1995, Volume: 44, Issue:4

    Topics: Adult; Aged; Aldosterone; Anesthesia, Intravenous; Atrial Natriuretic Factor; Catecholamines; Droper

1995
Stimulation of aldosterone by ACTH in normal and hypertensive pregnancy.
    American journal of hypertension, 1995, Volume: 8, Issue:3

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hypertension; Pre-E

1995
Hormonal, blood pressure, and peritoneal transport response to short-term ACE inhibition.
    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 1994, Volume: 14, Issue:4

    Topics: Administration, Oral; Adult; Aldosterone; Biological Transport; Blood Pressure; Enalapril; Enalapril

1994
Hemodynamic and biochemical effects of the AT1 receptor antagonist irbesartan in hypertension.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Body Weigh

1995
The influence of salt intake on plasma calcitonin gene-related peptide in subjects with mild essential hypertension.
    Journal of hypertension, 1994, Volume: 12, Issue:11

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Calcitonin Gene-Related Peptide; Cross-Over S

1994
Does lipophilicity of angiotensin converting enzyme inhibitors selectively influence autonomic neural function in human hypertension?
    Journal of hypertension, 1994, Volume: 12, Issue:11

    Topics: Aldosterone; Autonomic Nervous System; Blood Pressure; Catecholamines; Cold Temperature; Cross-Over

1994
Crossover comparison of the effects of enalapril and captopril on potassium homeostasis in patients with mild hypertension.
    International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:12

    Topics: Aldosterone; Blood Pressure; Captopril; Circadian Rhythm; Cross-Over Studies; Drug Administration Sc

1994
Enhanced pressor responsiveness to norepinephrine in type II diabetes. Effect of ACE inhibition.
    Diabetes care, 1994, Volume: 17, Issue:12

    Topics: Adult; Aldosterone; Blood Pressure; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2;

1994
Effects of an angiotensin II receptor antagonist, TCV-116, on renal haemodynamics in essential hypertension.
    Blood pressure. Supplement, 1994, Volume: 5

    Topics: Adult; Aged; Aldosterone; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Bloo

1994
Hemodynamic and neurohumoral effects of fish oil in hypertensive patients.
    American journal of hypertension, 1993, Volume: 6, Issue:12

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Blood Pressure

1993
Salt sensitivity and the blood pressure response to verapamil.
    American journal of hypertension, 1994, Volume: 7, Issue:6

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hyp

1994
Low plasma 19-hydroxyandrostenedione levels in patients with aldosterone-producing adenoma.
    Endocrine journal, 1993, Volume: 40, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Androstenedione; Blood Pressure; Dexamet

1993
Randomly allocated study of the effects of standard therapy versus ACE inhibition on micro-albuminuria in essential hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1994, Volume: 12, Issue:4

    Topics: Adrenergic beta-Antagonists; Albuminuria; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blo

1994
[The importance of studying the renin-angiotensin-aldosterone system in essential arterial hypertension in clinical practice. Activity of the renin-angiotensin-aldosterone system during treatment of hypertension with ACE-inhibitors and beta blockers].
    Vnitrni lekarstvi, 1994, Volume: 40, Issue:9

    Topics: Adult; Aldosterone; Cross-Over Studies; Enalapril; Female; Humans; Hypertension; Male; Metoprolol; M

1994
Pressure-dependent, enhanced natriuretic response to low-dose, atrial natriuretic peptide infusion in essential hypertension.
    Journal of internal medicine, 1994, Volume: 236, Issue:6

    Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure;

1994
Hemodynamic and humoral effects of low-dose aspirin in treated and untreated essential hypertensive patients.
    Blood pressure, 1994, Volume: 3, Issue:4

    Topics: Adult; Aldosterone; Aspirin; Captopril; Cross-Over Studies; Double-Blind Method; Female; Hemodynamic

1994
Urinary kallikrein and salt sensitivity in essential hypertensive males.
    Kidney international, 1994, Volume: 46, Issue:3

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cross-Over Studies; Double-Blind Meth

1994
Effects of atrial natriuretic factor infusion on plasma prorenin levels in hypertensive males.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1994, Volume: 16, Issue:3

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Enzyme Precursors; Heart Rate; Humans

1994
Antihypertensive and humoral effects of verapamil and lacidipine in combination in hypertensive patients.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:5

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridi

1993
Amlodipine in ambulatory hypertensive patients: humoral and haemodynamic effects.
    International journal of clinical pharmacology research, 1993, Volume: 13, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Aldosterone; Amlodipine; Blood Pressure; Cholesterol; F

1993
Comparison of blood pressure and angiotensin responses to the renin inhibitor Ro 42-5892 and the angiotensin converting enzyme inhibitor enalapril in essential hypertension.
    Journal of hypertension, 1993, Volume: 11, Issue:8

    Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood P

1993
[Influence of chronic ketanserin therapy on blood pressure and certain humoral and metabolic factors in patients with mild to moderate primary essential hypertension].
    Polskie Archiwum Medycyny Wewnetrznej, 1993, Volume: 90, Issue:2

    Topics: Administration, Oral; Adult; Aldosterone; Cholesterol; Epinephrine; Female; Humans; Hypertension; Ke

1993
Responses to converting enzyme and renin inhibition. Role of angiotensin II in humans.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captop

1994
Divergent hemodynamic and hormonal responses to varying salt intake in normotensive subjects.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:3

    Topics: Adult; Age Factors; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Family Heal

1993
Brain natriuretic peptide: natriuretic and endocrine effects in essential hypertension.
    Journal of hypertension, 1993, Volume: 11, Issue:2

    Topics: Aldosterone; Cyclic GMP; Half-Life; Homeostasis; Humans; Hypertension; Male; Middle Aged; Natriuresi

1993
Endogenous erythropoietin and salt sensitivity of blood pressure in patients with essential hypertension.
    American journal of hypertension, 1993, Volume: 6, Issue:1

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Erythropoietin; Female; Humans; Hyper

1993
Efficacy of manidipine in the treatment of hypertension with renal impairment: a multicenter trial.
    American heart journal, 1993, Volume: 125, Issue:2 Pt 2

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Blood Urea Nitrogen; Calcium C

1993
The role of atrial natriuretic peptide in the diuretic effect of Ca2+ entry blockers.
    European journal of pharmacology, 1993, Mar-16, Volume: 233, Issue:1

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Diure

1993
Metoclopramide blocks bromocriptine induced antihypertensive effect in hypertensive patients.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:9

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Bromocriptine; Dopamine Antagonists; Dopamine

1995
Comparison of amlodipine and quinapril on ambulatory blood pressure and platelet function in hypertension.
    Journal of human hypertension, 1995, Volume: 9, Issue:8

    Topics: Adult; Aged; Aldosterone; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Age

1995
Effect of dexamethasone on plasma free dopamine: dopaminergic modulation in hypertensive patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1995, Volume: 18 Suppl 1

    Topics: Adult; Aldosterone; alpha-Methyltyrosine; Dexamethasone; Dopamine; Dopamine Agents; Epinephrine; Hum

1995
Dopaminergic regulation of aldosterone secretion: its pathophysiologic significance in subsets of primary aldosteronism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1995, Volume: 18 Suppl 1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Dopamine; Dopamine Antagonists; Female;

1995
Effects of felodipine, metoprolol and their combination on blood pressure at rest and during exercise and on volume regulatory hormones in hypertensive patients.
    Blood pressure, 1995, Volume: 4, Issue:5

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Double-Blind Method; Drug Thera

1995
'Captopril test', with blood pressure and peripheral renin as response variables in hypertensive patients with suspected renal artery stenosis.
    Journal of human hypertension, 1995, Volume: 9, Issue:9

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure Determination; Ca

1995
Improvement of insulin sensitivity by metformin treatment does not lower blood pressure of nonobese insulin-resistant hypertensive patients with normal glucose tolerance.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:4

    Topics: Adult; Aged; Alanine; Aldosterone; Blood Glucose; Blood Pressure; Body Weight; Cross-Over Studies; D

1996
Active kallikrein response to changes in sodium-chloride intake in essential hypertensive patients.
    Journal of the American Society of Nephrology : JASN, 1996, Volume: 7, Issue:3

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cross-Over Studies; Double-Blind Meth

1996
Quinapril ACE-inhibition effects on adrenergic parameters in moderate essential hypertension.
    Kidney international. Supplement, 1996, Volume: 55

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Catech

1996
Left ventricular structural and functional characteristics in patients with renovascular hypertension, primary aldosteronism and essential hypertension.
    American journal of hypertension, 1996, Volume: 9, Issue:6

    Topics: Adult; Aldosterone; Echocardiography; Female; Heart Ventricles; Humans; Hyperaldosteronism; Hyperten

1996
[Concentration of neuropeptide Y in serum of patients with primary hypertension].
    Polskie Archiwum Medycyny Wewnetrznej, 1996, Volume: 95, Issue:5

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Endothelins; Female; Humans; Hypertension; Male

1996
Behaviour of adrenomedullin during acute and chronic salt loading in normotensive and hypertensive subjects.
    Clinical science (London, England : 1979), 1996, Volume: 91, Issue:3

    Topics: Adrenomedullin; Adult; Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Body F

1996
Effects of magnesium on blood pressure and intracellular ion levels of Brazilian hypertensive patients.
    International journal of cardiology, 1996, Oct-11, Volume: 56, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Brazil; Cal

1996
Glucose load and renal sodium handling in mild essential hypertension on different sodium intakes.
    Journal of human hypertension, 1996, Volume: 10, Issue:8

    Topics: Adolescent; Adult; Aldosterone; C-Peptide; Cross-Over Studies; Diet, Sodium-Restricted; Double-Blind

1996
Interruption of prolonged ramipril treatment in hypertensive patients: effects on the renin-angiotensin system.
    Fundamental & clinical pharmacology, 1996, Volume: 10, Issue:5

    Topics: Aldosterone; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhi

1996
The effects of angiotensin II receptor blockade with losartan on systemic blood pressure and renal and extrarenal prostaglandin synthesis in women with essential hypertension.
    American journal of hypertension, 1995, Volume: 8, Issue:12 Pt 1

    Topics: Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphen

1995
[Selected components of the kallikrein-kinin system and of the renin-angiotensin-aldosterone system in offspring of parents with hypertension].
    Annales Academiae Medicae Stetinensis, 1996, Volume: 42

    Topics: Adult; Aldosterone; Body Mass Index; Family Health; Female; Humans; Hypertension; Kallikrein-Kinin S

1996
Effects of carbidopa and of intravenous saline infusion into normal and hypertensive subjects on urinary free and conjugated dopamine.
    Journal of hypertension, 1997, Volume: 15, Issue:7

    Topics: Adolescent; Adult; Aldosterone; Aromatic Amino Acid Decarboxylase Inhibitors; Atrial Natriuretic Fac

1997
Circulating kallikreins in normotensive and hypertensive humans: effects of mineralocorticoid administration.
    Blood pressure, 1997, Volume: 6, Issue:4

    Topics: Adult; Aldosterone; Blood Pressure; Female; Fludrocortisone; Heart Rate; Humans; Hypertension; Kalli

1997
The effects of long-term treatment on left ventricular hypertrophy in patients with essential hypertension: relation to changes in neurohumoral factors.
    Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:5

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atrial

1997
[Effect of 12-week treatment with amlodipine on plasma renin activity and adrenal cortex function in patients with essential hypertension].
    Polskie Archiwum Medycyny Wewnetrznej, 1997, Volume: 98, Issue:8

    Topics: Adult; Aldosterone; Amlodipine; Antihypertensive Agents; Female; Humans; Hydrocortisone; Hypertensio

1997
Renin status does not predict the anti-hypertensive response to angiotensin-converting enzyme inhibition in African-Americans. Trandolapril Multicenter Study Group.
    Journal of human hypertension, 1998, Volume: 12, Issue:3

    Topics: Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People;

1998
Responses of natriuretic peptides to acute and chronic salt loading in normotensive and hypertensive subjects.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1998, Volume: 21, Issue:1

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Female; Humans; Hypertension; I

1998
Circulating plasma prekallikrein and tissue kallikrein in normotensive and hypertensive humans: effects of angiotensin II infusion.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1998, Volume: 20, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Infusions, Intravenous; Ka

1998
Inhibition of neutral endopeptidase causes vasoconstriction of human resistance vessels in vivo.
    Circulation, 1998, Jun-16, Volume: 97, Issue:23

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Fac

1998
Increased arterial distensibility in postmenopausal hypertensive women with and without hormone replacement therapy after acute administration of the ACE inhibitor moexipril.
    Cardiovascular drugs and therapy, 1998, Volume: 12, Issue:4

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Blood Pressure; Double-B

1998
Metoclopramide and domperidone block the antihypertensive effect of bromocriptine in hypertensive patients.
    American journal of therapeutics, 1998, Volume: 5, Issue:2

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Bromocriptine; Case-Control Studies; Cr

1998
Effects of eprosartan versus enalapril in hypertensive patients on the renin-angiotensin-aldosterone system and safety parameters: results from a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group.
    Current medical research and opinion, 1999, Volume: 15, Issue:1

    Topics: Acrylates; Adult; Aged; Aged, 80 and over; Aldosterone; Analysis of Variance; Angiotensin II; Angiot

1999
Effects of spironolactone and angiotensin-converting enzyme inhibitor on left ventricular hypertrophy in patients with essential hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1999, Volume: 22, Issue:1

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Drug Therapy, Combination; Ec

1999
The state and responsiveness of the renin-angiotensin-aldosterone system in patients with type II diabetes mellitus.
    American journal of hypertension, 1999, Volume: 12, Issue:4 Pt 1

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Diabetes Mellitus, Type 2; Diet, Sodium-Restricted; Female

1999
Angiotensin II stimulates left ventricular hypertrophy in hypertensive patients independently of blood pressure.
    American journal of hypertension, 1999, Volume: 12, Issue:4 Pt 1

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Data Interpretation, Statistical; Dose-Response

1999
[The effect of reduced sodium intake on blood pressure, body weight, renin, aldosterone, catecholamines, cholesterol and triglycerides. A meta-analysis].
    Ugeskrift for laeger, 1999, Apr-26, Volume: 161, Issue:17

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Catecholamines; Cholesterol; Diet, Sodium-Res

1999
Dose-response efficacy of valsartan, a new angiotensin II receptor blocker.
    Journal of human hypertension, 1999, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihyperten

1999
Acute hypotensive, natriuretic, and hormonal effects of nifedipine in salt-sensitive and salt-resistant black normotensive and hypertensive subjects.
    Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:3

    Topics: Adult; Aldosterone; Antihypertensive Agents; Black People; Blood Pressure; Calcium Channel Blockers;

1999
Plasma human atrial natriuretic peptide, endothelin-1, aldosterone and plasma-renin activity in pregnancy-induced hypertension.
    Journal of hypertension, 1999, Volume: 17, Issue:9

    Topics: Adolescent; Adult; Aldosterone; Atrial Natriuretic Factor; Endothelin-1; Female; Humans; Hypertensio

1999
Altered adrenal sensitivity to angiotensin II in low-renin essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:3

    Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin II; Black People; Demography; Female; Humans; Hypert

1999
Raised aldosterone to renin ratio predicts antihypertensive efficacy of spironolactone: a prospective cohort follow-up study.
    British journal of clinical pharmacology, 1999, Volume: 48, Issue:5

    Topics: Aldosterone; Anti-Inflammatory Agents; Antihypertensive Agents; Female; Fludrocortisone; Follow-Up S

1999
Effects of the nonpeptide V(1) vasopressin receptor antagonist SR49059 in hypertensive patients.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:6

    Topics: Administration, Oral; Adult; Aldosterone; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopr

1999
Aldosterone synthase gene (CYP11B2) C-344T polymorphism in Caucasians from the Berlin Salt-Sensitivity Trial (BeSST).
    Journal of hypertension, 1999, Volume: 17, Issue:11

    Topics: Adult; Aldosterone; Alleles; Angiotensinogen; Anthropometry; Blood Pressure; Cross-Over Studies; Cyt

1999
Modification of intracellular calcium and plasma renin by dietary calcium in men.
    American journal of hypertension, 1999, Volume: 12, Issue:12 Pt 1-2

    Topics: Adult; Aldosterone; Biomarkers; Blood Platelets; Blood Pressure; Calcitriol; Calcium; Calcium, Dieta

1999
Impact of aldosterone on left ventricular structure and function in young normotensive and mildly hypertensive subjects.
    The American journal of cardiology, 2000, May-15, Volume: 85, Issue:10

    Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hypertension; Mal

2000
Trandolapril does not improve insulin sensitivity in patients with hypertension and type 2 diabetes: a double-blind, placebo-controlled crossover trial.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:5

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; C

2000
Renal haemodynamics and sodium excretory capacity during urapidil treatment in patients with essential hypertension.
    Journal of hypertension, 2000, Volume: 18, Issue:7

    Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Biomarkers; Ca

2000
Antihypertensive effect of valyl-tyrosine, a short chain peptide derived from sardine muscle hydrolyzate, on mild hypertensive subjects.
    Journal of human hypertension, 2000, Volume: 14, Issue:8

    Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Dipeptides; Dou

2000
Efficacy of candesartan cilexetil alone or in combination with amlodipine and hydrochlorothiazide in moderate-to-severe hypertension. UK and Israel Candesartan Investigators.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:3

    Topics: Aldosterone; Amlodipine; Analysis of Variance; Antihypertensive Agents; Benzimidazoles; Biphenyl Com

2000
Treatment of familial hyperaldosteronism type I: only partial suppression of adrenocorticotropin required to correct hypertension.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:9

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hyperal

2000
The effects of verapamil SR and bisoprolol on reducing the sympathetic nervous system's activity.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23, Issue:5

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Bisoprolol; Blood Pressure; Calcium Channel Blockers; Endo

2000
Hemodynamic, hormone, and urinary effects of adrenomedullin infusion in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:4

    Topics: Adrenomedullin; Adult; Aldosterone; Atrial Natriuretic Factor; Creatinine; Cross-Over Studies; Cycli

2000
Proximal sodium reabsorption: An independent determinant of blood pressure response to salt.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:4

    Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Electrolytes; Fem

2000
Dose response effect of conjugated equine oestrogen on blood pressure in postmenopausal women with hypertension.
    Blood pressure, 2000, Volume: 9, Issue:5

    Topics: Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Cross-Over Stu

2000
C825T polymorphism of the G protein beta(3)-subunit and antihypertensive response to a thiazide diuretic.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2

    Topics: Adult; Age Factors; Aldosterone; Alleles; Antihypertensive Agents; Blood Pressure; Diuretics; Female

2001
Adverse cardiac effects of salt with fludrocortisone in hypertension.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:3

    Topics: Aldosterone; Anti-Inflammatory Agents; Echocardiography; Electrocardiography; Electrolytes; Female;

2001
Absence of D147E mutation of CYP11B2 gene in hypertensive patients with increased corticosterone and aldosterone production.
    European journal of endocrinology, 2001, Volume: 144, Issue:4

    Topics: Aged; Aldosterone; Corticosterone; Cytochrome P-450 CYP11B2; Exons; Female; Genotype; Humans; Hypert

2001
Effect of salt intake on endothelium-derived factors in a group of patients with essential hypertension.
    Clinical science (London, England : 1979), 2001, Volume: 101, Issue:1

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure Monitoring, Ambu

2001
Effect of short-term losartan treatment in patients with primary aldosteronism and essential hypertension.
    Methods and findings in experimental and clinical pharmacology, 2001, Volume: 23, Issue:3

    Topics: Administration, Oral; Age Factors; Aldosterone; Angiotensin Receptor Antagonists; Antihypertensive A

2001
Performance of the basal aldosterone to renin ratio and of the renin stimulation test by furosemide and upright posture in screening for aldosterone-producing adenoma in low renin hypertensives.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:9

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Area Under Curve; Case-Control Studies; Diuret

2001
Importance of the renin system for determining blood pressure fall with acute salt restriction in hypertensive and normotensive whites.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hyperten

2001
Role of weight loss and polyunsaturated fatty acids in improving metabolic fitness in moderately obese, moderately hypertensive subjects.
    Journal of hypertension, 2001, Volume: 19, Issue:10

    Topics: Aldosterone; Blood Pressure; Body Composition; Dietary Fats; Fatty Acids; Fatty Acids, Omega-3; Fatt

2001
Inhibitory effect of telmisartan on the blood pressure response to angiotensin II challenge.
    Journal of cardiovascular pharmacology, 2001, Volume: 38, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme

2001
Evaluation of plasma levels of renin-aldosterone and blood pressure in women over 35 years treated with new oral contraceptives.
    Contraception, 2001, Volume: 64, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Contraceptives, Oral; Drug Evaluation; Ethinyl Estr

2001
Angiotensinogen gene core promoter variants and non-modulating hypertension.
    Hypertension (Dallas, Tex. : 1979), 2001, Dec-01, Volume: 38, Issue:6

    Topics: Adult; Aldosterone; Angiotensinogen; Angiotensins; Genetic Linkage; Genotype; Humans; Hypertension;

2001
Omapatrilat versus lisinopril: efficacy and neurohormonal profile in salt-sensitive hypertensive patients.
    Hypertension (Dallas, Tex. : 1979), 2001, Dec-01, Volume: 38, Issue:6

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood

2001
Long-term effects of olmesartan, an Ang II receptor antagonist, on blood pressure and the renin-angiotensin-aldosterone system in hypertensive patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2001, Volume: 24, Issue:6

    Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Antihyper

2001
Spironolactone abolishes the relationship between aldosterone and plasminogen activator inhibitor-1 in humans.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:2

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Diuretics; Do

2002
Angiotensinogen genotype affects renal and adrenal responses to angiotensin II in essential hypertension.
    Circulation, 2002, Apr-23, Volume: 105, Issue:16

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Antihypertens

2002
Aldosterone synthase (CYP11B2) -344 C/T polymorphism is related to antihypertensive response: result from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial.
    American journal of hypertension, 2002, Volume: 15, Issue:5

    Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin Receptor Antagonists; Antihypertensive Agents;

2002
Amiloride, a specific drug for hypertension in black people with T594M variant?
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:1

    Topics: Aldosterone; Amiloride; Amino Acid Substitution; Atrial Natriuretic Factor; Black People; Blood Pres

2002
Effects of beta-adrenoreceptor blocking drugs on plasma volume. Renin and aldosterone as components of their antihypertensive action.
    Drugs, 1976, Volume: 11 SUPPL 1

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Antihypertensive Agents; Clinical Trials as Topic;

1976
Long term non-selective and cardioselective beta-receptor blockade in hypertensive patients. Effects on circulatory parameters, catecholamines and renin activity under basal conditions and in connection with exercise and hypoglycemia.
    Acta medica Scandinavica. Supplementum, 1976, Volume: 598

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Glucose; Blood Pressure; Clinical Trial

1976
[The renin-aldosterone system in essential hypertension--hypotensive action of beta adrenergic blocking agents and variation of the renin-aldosterone system (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1977, Oct-20, Volume: 53, Issue:10

    Topics: Adrenergic beta-Antagonists; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Met

1977
Labetalol in the treatment of severe essential hypertension: relationship between arterial blood pressure, plasma catecholamines, plasma renin activity, plasma aldosterone and body weight.
    Acta medica Scandinavica. Supplementum, 1979, Volume: 625

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Pressure;

1979
[Treatment of essential hypertension with propranolol (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1976, Oct-08, Volume: 101, Issue:41

    Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Clinical Trials as Topic; Creatinine; Cyclic AMP; F

1976
Reduction of plasma renin activity by inhibition of the fatty acid cyclooxygenase in human subjects: independence of sodium retention.
    Circulation research, 1979, Volume: 44, Issue:6

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Clinical Trials as Topic; Creatinine; Cycloox

1979
Hormonal changes with long-term converting-enzyme inhibition by captopril in essential hypertension.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; B

1979
[Effect of chronic beta-adrenergic blockade on blood pressure and release of renin, aldosterone and cortisol in essential hypertension (author's transl)].
    Klinische Wochenschrift, 1975, Oct-01, Volume: 53, Issue:19

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Circadian Rhythm; Clinical Trials a

1975
Spironolactone and hydrochlorothiazide in normal-renin and low-renin essential hypertension.
    Clinical pharmacology and therapeutics, 1977, Volume: 21, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; H

1977
Mineralocorticoid hypertension in childhood.
    Mayo Clinic proceedings, 1977, Volume: 52, Issue:5

    Topics: 18-Hydroxydesoxycorticosterone; Adolescent; Aldosterone; Blood Pressure; Child, Preschool; Clinical

1977
Effect of minoxidil on blood pressure and hemodynamics in severe hypertension.
    The American journal of cardiology, 1977, May-26, Volume: 39, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Drug Therapy, Combinat

1977
Long term treatment of moderate hypertension with the beta1-receptor blocking agent metoprolol. I. Effect on maximal working capacity, plasma catecholamines and renin, Urinary aldosterone, blood pressure and pulse rate under basal conditions.
    European journal of clinical pharmacology, 1977, Apr-20, Volume: 11, Issue:4

    Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Clinical Trials as Topic; Epinephrine; Hemodynam

1977
Relationship of plasma renin activity and aldosterone levels with hemodynamic functions in essential hypertension.
    Archives of internal medicine, 1977, Volume: 137, Issue:8

    Topics: Adult; Aldosterone; Blood Pressure; Blood Volume; Blood Volume Determination; Cardiac Output; Cardia

1977
Renin-aldosterone profiling in hypertension.
    Annals of internal medicine, 1977, Volume: 87, Issue:5

    Topics: Aldosterone; Angiotensin II; Benzothiadiazines; Clinical Trials as Topic; Diagnosis, Differential; D

1977
[Systematic analysis of various blood pressure regulating factors in diabetes mellitus].
    Schweizerische medizinische Wochenschrift, 1977, Dec-10, Volume: 107, Issue:49

    Topics: Aldosterone; Catecholamines; Clinical Trials as Topic; Creatinine; Diabetes Complications; Diabetes

1977
Response of blood pressure and the renin-angiotensin-aldosterone axis to hypotensive therapy: comparison of propranolol with spironolactone.
    The New Zealand medical journal, 1977, Sep-14, Volume: 86, Issue:595

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Female; Furosemide; Hu

1977
Alpha and beta adrenergic blockade with orally administered labetalol in hypertension. Studies on blood volume, plasma renin and aldosterone and catecholamine excretion.
    The American journal of cardiology, 1978, Volume: 41, Issue:3

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Volume; Body Weight; Chlorthalidone; Clinical Trials

1978
[Spironolactone-induced changes of the renin-angiotensin-aldosterone system and blood pressure lowering in essential hypertension].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Humans; Hype

1977
Relationships of renin and aldosterone to antihypertensive effects of spironolactone and propranolol.
    Journal of clinical pharmacology, 1978, Volume: 18, Issue:7

    Topics: Adult; Aldosterone; Antihypertensive Agents; Clinical Trials as Topic; Female; Humans; Hypertension;

1978
Hydrochlorothiazide and spironolactone in hypertension.
    Clinical pharmacology and therapeutics, 1979, Volume: 25, Issue:1

    Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Clinical Trials as Topic; Cr

1979
The renin-aldosterone system in dihydralazine therapy during hypertensive pregnancy.
    International journal of clinical pharmacology and biopharmacy, 1978, Volume: 16, Issue:12

    Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Dihydralazine; Electrolytes; Female; H

1978
A comparative study of the effects of oxprenolol versus propranolol in essential hypertension.
    Journal of clinical pharmacology, 1979, Volume: 19, Issue:1

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Hum

1979
Effects of beta 1-selective and non-selective beta-blockade on blood pressure, plasma renin activity and plasma aldosterone in hypertensive patients.
    The Netherlands journal of medicine, 1979, Volume: 22, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation;

1979
Once-daily metoprolol in primary hypertension.
    Clinical pharmacology and therapeutics, 1979, Volume: 25, Issue:4

    Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Drug Administration Schedule; Electrol

1979
Haemodynamic effects of captopril in hypertensive patients: comparison with saralasin.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Captopril; Cardiac Output; Clinical Trials as Topic; He

1979
Effect of increasing doses of labetalol on blood pressure, plasma renin activity and aldosterone in hypertensive patients.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Etha

1979
[Correlation between plasma volume and plasma renin activity, aldosteronemia, blood electrolytes and arterial pressure in a group of randomized hypertensives].
    Bollettino della Societa italiana di cardiologia, 1979, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Electrolytes; Female; Humans; Hypertension; Male; Mi

1979
Clonidine in primary hypertension: effects on blood pressure, plasma renin activity, plasma and urinary aldosterone.
    Current therapeutic research, clinical and experimental, 1977, Volume: 21, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Humans; Hypertensio

1977
The influence of sar1 ala8 angiotensin II (saralasin) on plasma aldosterone in hypertensive patients.
    Acta medica Scandinavica, 1979, Volume: 205, Issue:3

    Topics: Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypertension, Reno

1979
The renin-aldosterone system and thiazide-induced depletion of total body potassium in essential hypertension.
    Nephron, 1978, Volume: 21, Issue:5

    Topics: Adult; Aged; Aldosterone; Body Weight; Chlorothiazide; Drug Therapy, Combination; Female; Humans; Hy

1978
Controlled treatment of primary hypertension with propranolol and spironolactone. A crossover study with special reference to initial plasma renin activity.
    The American journal of cardiology, 1976, Mar-31, Volume: 37, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hum

1976
Propranolol, renin and hypertension: a review.
    Postgraduate medical journal, 1976, Volume: 52 Suppl 4

    Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Child; Clinical Trials as Topic; Female; Human

1976
Effect of blood pressure angiotensin II and aldosterone concentrations during treatment of severe hypertension with intravenous labetalol: comparison with propranolol.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:4 Suppl 3

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Ethanolamines; Heart Rate; Hu

1976
[Antihypertensive effects of ecarazine hydrochloride in essential hypertension and its action on the renin-aldosterone system].
    Horumon to rinsho. Clinical endocrinology, 1976, Volume: 24, Issue:9

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Clinical Trials as Topic; Female; Heterocyclic Co

1976
Differential effects of acute and chronic beta-adrenoreceptor blockade on blood pressure and the renin-angiotensin-aldosterone system in essential hypertension.
    Clinical science and molecular medicine. Supplement, 1976, Volume: 3

    Topics: Adult; Aldosterone; Angiotensin II; Clinical Trials as Topic; Humans; Hypertension; Male; Pindolol;

1976
Effect of beta1-receptor blockade (Metoprolol, Selokenr) on blood pressure, pulse rate, plasma catecholamines, renin activity and urinary aldosterone.
    Acta medica Scandinavica. Supplementum, 1976, Volume: 602

    Topics: Aldosterone; Blood Pressure; Catecholamines; Clinical Trials as Topic; Drug Evaluation; Humans; Hype

1976
Anti-hypertensive adrenergic-blocking agents: effects on sodium balance, the renin-angiotensin system and haemodynamics.
    Clinical science and molecular medicine. Supplement, 1975, Volume: 2

    Topics: Adult; Aldosterone; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Clonidine; Female; Gua

1975
Effect of sotalol on haemodynamics and renin-angiotensin-aldosterone system in hypertensive patients.
    Clinical science and molecular medicine, 1976, Volume: 51, Issue:1

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Female; Heart Rate; Humans

1976
Effect of high dose spironolactone and chlorthalidone in essential hypertension: relation to plasma renin activity and plasma volume.
    Australian and New Zealand journal of medicine, 1975, Volume: 5, Issue:1

    Topics: Adult; Aldosterone; Body Weight; Chlorthalidone; Female; Humans; Hypertension; Male; Middle Aged; Pl

1975
Effects of intravenous labetalol on blood pressure, angiotensin II and aldosterone in hypertension: comparison with propranolol.
    Clinical science and molecular medicine. Supplement, 1976, Volume: 3

    Topics: Aldosterone; Angiotensin II; Depression, Chemical; Ethanolamines; Heart Rate; Humans; Hypertension;

1976
Aldosterone and renin in essential hypertension.
    Canadian Medical Association journal, 1975, Sep-06, Volume: 113, Issue:5

    Topics: 18-Hydroxydesoxycorticosterone; Adult; Age Factors; Aldosterone; Angiotensin II; Clinical Trials as

1975
Intrapatient comparison of treatment with chlorthalidone, spironolactone and propranolol in normoreninemic essential hypertension.
    The American journal of cardiology, 1975, Oct-31, Volume: 36, Issue:5

    Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Chlorthalidone; Clinical Trials as Topic; Creatinin

1975
Antagonism of the effects of furosemide by indomethacin in normal and hypertensive man.
    Prostaglandins, 1975, Volume: 10, Issue:4

    Topics: Aldosterone; Blood Pressure; Clinical Trials as Topic; Drug Interactions; Furosemide; Humans; Hypert

1975
Contraceptive steroids and hypertension.
    Journal of steroid biochemistry, 1975, Volume: 6, Issue:6

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Deoxycholic Acid; Female; Humans;

1975
Twenty-four hour blood pressure effect of once-daily lisinopril, enalapril, and placebo in patients with mild to moderate hypertension.
    Journal of human hypertension, 1992, Volume: 6, Issue:4

    Topics: Adult; Aged; Aldosterone; Ambulatory Care; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure;

1992
Comparative effects of dopaminergic agonists on cardiovascular, renal, and renin-angiotensin systems in hypertensive patients.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:1

    Topics: Aldosterone; Blood Pressure; Bromocriptine; Creatinine; Dopamine Agents; Female; Heart Rate; Hemodyn

1992
Short-term strenuous exercise training: effects on blood pressure and hormonal levels in mild hypertension.
    Irish journal of medical science, 1992, Volume: 161, Issue:12

    Topics: Adult; Aldosterone; Blood Pressure; Chromogranin A; Chromogranins; Epinephrine; Exercise Therapy; Fo

1992
Long-term diuretic therapy: effects of dose reduction on antihypertensive efficacy and counterregulatory systems.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:3

    Topics: Aldosterone; Benzothiadiazines; Blood Pressure; Body Weight; Diuretics; Dose-Response Relationship,

1992
Hemodynamic and humoral effects of the novel calcium antagonist Ro 40-5967 in patients with hypertension.
    Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:3

    Topics: Aldosterone; Benzimidazoles; Calcium Channel Blockers; Catecholamines; Drug Administration Schedule;

1992
Effect of atrial natriuretic peptide (8-33-Met ANP) in patients with hypertension.
    American journal of hypertension, 1992, Volume: 5, Issue:5 Pt 1

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Bradycardia; Diuresis; Double-Blind M

1992
Effects of sustained-release nicardipine on regression of left ventricular hypertrophy in systemic hypertension.
    The American journal of cardiology, 1992, Jun-15, Volume: 69, Issue:19

    Topics: Aldosterone; Blood Pressure; Cardiomegaly; Delayed-Action Preparations; Double-Blind Method; Echocar

1992
[Several indicators of hormonal homeostasis (hypophysis--gonads) in patients with hypertension].
    Rossiiskii meditsinskii zhurnal : organ Ministerstva zdravookhraneniia RSFSR, 1992, Issue:3

    Topics: Adult; Aldosterone; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Gonadotropins, Pituitary

1992
Comparisons of long-term effects between converting enzyme inhibitors and conventional therapy in treating mild to moderate hypertension.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1991, Volume: 48, Issue:5

    Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Electroca

1991
Single administration of captopril and combined use with beta-blocker and/or thiazide diuretic in the treatment of essential hypertension.
    Angiology, 1991, Volume: 42, Issue:11

    Topics: Acebutolol; Adrenergic beta-Antagonists; Aldosterone; Benzothiadiazines; Blood Pressure; Captopril;

1991
Vascular pressor responses in treated and untreated essential hypertension.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; D

1990
Catecholamines and the renin-angiotensin-aldosterone system during treatment with felodipine ER or hydrochlorothiazide in essential hypertension.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:3

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Delayed-Action Preparations; Double-Blind

1991
Hemodynamic and humoral interactions between perindopril and indomethacin in essential hypertensive subjects.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 7

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; D

1991
Short-term effects of atenolol and nifedipine on atrial natriuretic peptide, plasma renin activity, and plasma aldosterone in patients with essential hypertension.
    Journal of clinical pharmacology, 1991, Volume: 31, Issue:3

    Topics: Adult; Aldosterone; Atenolol; Atrial Natriuretic Factor; Female; Humans; Hypertension; Male; Middle

1991
Isradipine in the treatment of hypertension. Some additional effects observed during a one-year study.
    American journal of hypertension, 1991, Volume: 4, Issue:2 Pt 2

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Echocardiography; Exercise; Femal

1991
Acute and sustained changes in sodium balance during nifedipine treatment in essential hypertension.
    The American journal of medicine, 1991, Volume: 91, Issue:3

    Topics: Aged; Aldosterone; Analysis of Variance; Atrial Natriuretic Factor; Blood Pressure; Delayed-Action P

1991
Atrial natriuretic peptide inhibits the aldosterone response to metoclopramide in patients with glomerular disease and essential hypertension.
    Clinical and experimental pharmacology & physiology, 1991, Volume: 18, Issue:8

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Female; Glomerulonephritis; Heart Rat

1991
Dietary sodium and inhibition of neutral endopeptidase 24.11 in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 18, Issue:6

    Topics: Adult; Aldosterone; Analysis of Variance; Atrial Natriuretic Factor; Blood Pressure; Creatine; Heart

1991
Effects of antihypertensive drugs on glomerular function in normotensive and hypertensive subjects: hormonal aspects.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Dietary Carbohydrates; Dietary Proteins; Enalapril; F

1991
Glucose tolerance and insulin secretion in essential hypertension after treatment with an angiotensin converting enzyme inhibitor.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Cilazapril; Female; Glucose To

1991
Response to the cold pressor test in normotensive and hypertensive patients.
    American journal of hypertension, 1991, Volume: 4, Issue:7 Pt 1

    Topics: Aldosterone; Blood Pressure; Cold Temperature; Humans; Hypertension; Posture; Reflex; Renin

1991
The influence of oral potassium citrate/bicarbonate on blood pressure in essential hypertension during unrestricted salt intake.
    Klinische Wochenschrift, 1991, Volume: 69 Suppl 25

    Topics: Adult; Aldosterone; Bicarbonates; Blood Pressure; Citrates; Female; Humans; Hypertension; Male; Midd

1991
Effects of carvedilol on renal function.
    European journal of clinical pharmacology, 1990, Volume: 38 Suppl 2

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Carbazoles; Carvedilol; Double-Blin

1990
Sodium restriction in hypertensive patients treated with a converting enzyme inhibitor and a thiazide.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:6 Pt 1

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Double-Blind Metho

1991
Co-dergocrine mesylate inhibits the increase in plasma catecholamines caused by nifedipine in essential hypertension.
    European journal of clinical pharmacology, 1990, Volume: 39, Issue:5

    Topics: Aldosterone; Catecholamines; Dihydroergotoxine; Drug Therapy, Combination; Female; Humans; Hypertens

1990
Effect of the circulating renin-angiotensin system on prolactin release in humans.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 70, Issue:1

    Topics: Adenoma; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Circadian Rhythm; Enalapril; Humans;

1990
Effects of captopril and minoxidil on left ventricular hypertrophy in resistant hypertensive patients: a 6 month double-blind comparison.
    Journal of the American College of Cardiology, 1990, Volume: 16, Issue:1

    Topics: Adult; Aged; Aldosterone; Captopril; Cardiomegaly; Double-Blind Method; Echocardiography; Humans; Hy

1990
Inverse relationship between upright plasma renin activity and twenty-four hour blood pressure variability in borderline hypertension.
    Journal of hypertension, 1990, Volume: 8, Issue:10

    Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Male; Postur

1990
The effects of nicardipine on sodium and calcium metabolism in hypertensive patients: a chronic study.
    Journal of clinical pharmacology, 1990, Volume: 30, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aldosterone; Calcium; Double-Blind Method; Female; Humans; Hypert

1990
Comparison of the renal effects of dilevalol and carteolol in patients with mild to moderate essential hypertension.
    European journal of clinical pharmacology, 1990, Volume: 38, Issue:3

    Topics: Adult; Aldosterone; Blood Proteins; Carteolol; Female; Glomerular Filtration Rate; Hemodynamics; Hum

1990
Antihypertensive and renal effects of enalapril and slow-release verapamil in essential hypertension. A double-blind, randomized study.
    European journal of clinical pharmacology, 1990, Volume: 39 Suppl 1

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Delayed-Action Preparations; Double-Blind Method

1990
Efficacy of nicardipine slow release (SR) on hypertension, potassium balance and plasma aldosterone in idiopathic aldosteronism.
    Journal of human hypertension, 1990, Volume: 4, Issue:5

    Topics: Administration, Oral; Adult; Aldosterone; Blood Pressure; Delayed-Action Preparations; Female; Human

1990
Ketanserin and captopril interaction in the treatment of essential hypertensives.
    Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 1

    Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Captopril; Double-Blind Method; Drug Therapy, Combi

1990
Effect of ketanserin in primary aldosteronism.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 7

    Topics: Aldosterone; Blood Pressure; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Ketanserin; P

1985
Moderate sodium restriction, angiotensin converting enzyme inhibition, and thiazide diuretic in the management of essential hypertension.
    Journal of cardiovascular pharmacology, 1989, Volume: 13 Suppl 3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Diet, So

1989
[Effect of a calcium inhibitor, nicardipine, on aldosterone secretion in primary hyperaldosteronism].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82, Issue:7

    Topics: Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hypera

1989
Prolonged decrease in blood pressure after atrial natriuretic peptide infusion in essential hypertension: a new anti-pressor mechanism?
    Clinical science (London, England : 1979), 1989, Volume: 77, Issue:3

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Diet, Sodium-Restricted; Female

1989
Increase of plasma atrial natriuretic peptide levels after sublingual administration of nifedipine in essentially hypertensive patients.
    International journal of cardiology, 1989, Volume: 25 Suppl 1

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Heart Rate; Humans; Hypertension; Mid

1989
Fosenopril, an angiotensin-converting enzyme inhibitor, and propranolol: comparative effects at rest and exercise on blood pressure, hormonal variables, and plasma potassium in essential hypertension.
    Cardiovascular drugs and therapy, 1989, Volume: 3, Issue:1

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; Exercise

1989
Acute calcium entry blockade inhibits the blood pressure but not the hormonal responses to angiotensin II.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:6

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers;

1989
Comparison of intravenous dilevalol with placebo in moderate hypertension.
    Clinical pharmacology and therapeutics, 1989, Volume: 46, Issue:4

    Topics: Aldosterone; Atrial Natriuretic Factor; Catecholamines; Cyclic GMP; Double-Blind Method; Humans; Hyp

1989
Captopril versus enalapril maleate: a comparison of antihypertensive and hormonal effects.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 1

    Topics: Adult; Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopr

1985
Influence of food on acute and chronic effects of captopril in essential hypertensive patients.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 1

    Topics: Adult; Aldosterone; Captopril; Fasting; Female; Food; Hemodynamics; Humans; Hypertension; Male; Midd

1985
Therapeutic value of calcium antagonists in autonomous hyperaldosteronism.
    Klinische Wochenschrift, 1989, Feb-15, Volume: 67, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Fema

1989
Does hormone analysis predict the antihypertensive response of basic medical treatment?
    Herz, 1989, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Clinical Trials as Topic; Dinoprost; Dinoprostone; Female; Humans; H

1989
The haemodynamic and hormonal responses after clonidine occur independently of sedation in essential hypertension.
    British journal of clinical pharmacology, 1989, Volume: 28, Issue:3

    Topics: Adult; Aldosterone; Clonidine; Epinephrine; Female; Hemodynamics; Hormones; Humans; Hypertension; Hy

1989
Hypertensive dysregulation and its modification by calcium channel blockade in nonoliguric renal failure.
    American journal of nephrology, 1989, Volume: 9, Issue:4

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Catecholamines;

1989
Antihypertensive and humoral effects of nifedipine in essential hypertension uncontrolled by hydrochlorothiazide alone.
    American journal of hypertension, 1989, Volume: 2, Issue:11 Pt 1

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therap

1989
Preliminary observations of the acute effects of selective serum thromboxane inhibition and angiotensin converting enzyme inhibition on blood pressure and renal hemodynamics in hypertensive humans.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:12

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Clinical Tr

1989
Crossover design for the dose determination of an angiotensin converting enzyme inhibitor in hypertension.
    Journal of hypertension, 1989, Volume: 7, Issue:12

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Bl

1989
Reversal of diuretic-induced secondary hyperaldosteronism and hypokalemia by trilostane, an inhibitor of adrenal steroidogenesis.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:4

    Topics: Aldosterone; Blood Pressure; Dihydrotestosterone; Diuretics; Double-Blind Method; Female; Humans; Hy

1989
Mechanism of impaired natriuretic response to furosemide during prolonged therapy.
    Kidney international, 1989, Volume: 36, Issue:4

    Topics: Adult; Aged; Aldosterone; Body Weight; Chlorothiazide; Furosemide; Humans; Hypertension; Male; Middl

1989
[Clinical pharmacology of a single doses of captopril and enalapril. Controlled study in subjects with essential hypertension].
    Recenti progressi in medicina, 1987, Volume: 78, Issue:4

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Captopril; Clinical Trials as Topic; Double-Blind Method;

1987
[Definition and consequences of blocking the renin-angiotensin system by converting enzyme inhibition].
    Archives des maladies du coeur et des vaisseaux, 1987, Volume: 80, Issue:6

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Drug Administration Schedule; Enalapril; Female; Humans; H

1987
Antihypertensive effect of enalapril in essential hypertension: role of prostacyclin.
    The American journal of the medical sciences, 1987, Volume: 294, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aldosterone; Enalapril; Epoprostenol; Female; Humans; Hyp

1987
Unrelated responses of brachial artery hemodynamics and renin-angiotensin system to acute converting enzyme inhibition by enalaprilat in essential hypertension.
    The American journal of cardiology, 1988, May-01, Volume: 61, Issue:13

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Brachial Artery; Clini

1988
[Effects of phenylephrine on atrial natriuretic factor and the renin-aldosterone axis in normal patients and essential hypertensive patients].
    Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81 Spec No

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Diuresis; Humans; Hyperte

1988
Humoral effects of metoclopramide and domperidone in normal subjects and in hypertensive patients.
    Journal of endocrinological investigation, 1988, Volume: 11, Issue:10

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Domperidone; Female; Humans; Hydrocortisone; Hypert

1988
Studies with fenoldopam, a dopamine receptor DA1 agonist, in essential hypertension.
    British journal of clinical pharmacology, 1986, Volume: 21, Issue:1

    Topics: Adult; Aldosterone; Benzazepines; Blood Pressure; Chromium Radioisotopes; Fenoldopam; Glomerular Fil

1986
Fenoldopam: effect on aldosterone secretion.
    British journal of clinical pharmacology, 1986, Volume: 21, Issue:2

    Topics: Aldosterone; Benzazepines; Double-Blind Method; Fenoldopam; Humans; Hypertension; Metoclopramide; Mi

1986
Renin and beta-blockade: prorenin and aldosterone may explain the controversy.
    Clinical nephrology, 1986, Volume: 25, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Dou

1986
Effect of fenoldopam on the aldosterone response to metoclopramide in man.
    Clinical endocrinology, 1986, Volume: 24, Issue:2

    Topics: Aldosterone; Benzazepines; Clinical Trials as Topic; Double-Blind Method; Fenoldopam; Humans; Hypert

1986
The clinical pharmacology of bopindolol, a new long-acting beta-adrenoceptor antagonist, in hypertension.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:4

    Topics: Adrenergic beta-Antagonists; Aldosterone; Cardiac Output; Clinical Trials as Topic; Epinephrine; Hea

1987
Renal haemodynamic and neurohumoral responses to urapidil in hypertensive man.
    Drugs, 1988, Volume: 35 Suppl 6

    Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Clinical Trial

1988
Ketanserin and prazosin: a comparison of antihypertensive and biochemical effects.
    Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Cholesterol; Drug Evaluation; Female; Heart Rate; Humans; Hypert

1986
Systemic and renal hemodynamic effects of celiprolol in essential hypertensives.
    The American journal of cardiology, 1988, Feb-10, Volume: 61, Issue:5

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Celiprolol; Clinical Trials as Topic; D

1988
Effects of fosenopril, a once-daily angiotensin-converting enzyme inhibitor, on resting and exercise-induced changes of blood pressure, hormonal variables, and plasma potassium in essential hypertension.
    American journal of hypertension, 1988, Volume: 1, Issue:3 Pt 3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Drug Administration Schedule;

1988
Effects of celiprolol on plasma renin, aldosterone, norepinephrine and epinephrine in primary hypertension.
    The American journal of cardiology, 1988, Oct-01, Volume: 62, Issue:10 Pt 1

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Celiprolol; Double-Blind Method; Epinephrine; Fem

1988
Inhibition of the aldosterone response to sodium depletion in man by stimulation of dopamine DA2 receptors.
    European journal of clinical pharmacology, 1988, Volume: 35, Issue:3

    Topics: Aged; Aldosterone; Dihydroergotoxine; Female; Humans; Hypertension; Male; Middle Aged; Receptors, Do

1988
Humoral effects of long-term oral enalapril therapy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1986, Volume: 7, Issue:5

    Topics: Administration, Oral; Aldosterone; Angiotensin II; Blood Pressure; Blood Specimen Collection; Clinic

1986
Time course of changes in blood pressure, aldosterone and body fluids during enalapril treatment: a double-blind randomized study vs hydrochlorothiazide plus propranolol in essential hypertension.
    Clinical and experimental pharmacology & physiology, 1986, Volume: 13, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Body Fluids; Clinical Trials as Topic; Double-Blind Method; Drug

1986
The pharmacodynamics and dose-response relationships of the angiotensin converting enzyme inhibitor, cilazapril, in essential hypertension.
    British journal of clinical pharmacology, 1986, Volume: 22, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Autonomic Nervous System; Blood

1986
The haemodynamic and humoral effects of treatment for one month with the angiotensin converting enzyme inhibitor perindopril in salt replete hypertensive patients.
    European journal of clinical pharmacology, 1987, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Age

1987
Moderate sodium restriction in hypertensive subjects: renal effects of ACE-inhibition.
    Kidney international, 1987, Volume: 31, Issue:3

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diet, Sodium-Restricte

1987
Enhanced response of plasma prolactin to metoclopramide during chronic converting enzyme inhibition.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1987, Volume: 19, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Enalapril; Female; Hum

1987
Effects of moderate low sodium/high potassium diet on essential hypertension: results of a comparative study.
    International journal of clinical pharmacology, therapy, and toxicology, 1988, Volume: 26, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Clinical Trials as Topic; Diet; Double-Blind Method

1988
Hormone, calcium and blood pressure relationships in primary hyperparathyroidism.
    Journal of hypertension, 1988, Volume: 6, Issue:9

    Topics: Aged; Aldosterone; Catecholamines; Female; Hormones; Humans; Hypercalcemia; Hyperparathyroidism; Hyp

1988
Antihypertensive response to ketanserin: influence of race and weight.
    Journal of clinical pharmacology, 1988, Volume: 28, Issue:11

    Topics: Adult; Aged; Aldosterone; Black People; Blood Pressure; Body Weight; Female; Heart Rate; Humans; Hyp

1988
Inducing hyperkalemia by converting enzyme inhibitors and heparin.
    Kidney international. Supplement, 1988, Volume: 25

    Topics: Acidosis; Acute Kidney Injury; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Drug Therapy,

1988
Intracellular sodium and the response to nitrendipine or atenolol in African blacks.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:1

    Topics: Adult; Africa; Aldosterone; Atenolol; Black People; Blood Pressure; Double-Blind Method; Erythrocyte

1988
The combination of prazosin and verapamil in the treatment of essential hypertension.
    Clinical pharmacology and therapeutics, 1988, Volume: 43, Issue:5

    Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Drug Therapy, Combination; Female; Heart Rate; H

1988
Captopril and nifedipine in combination for moderate to severe essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1987, Volume: 9, Issue:6

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Captopril; Drug Administration Schedule; Drug

1987
Multiple oral doses of nicardipine, a calcium-entry blocker: effects on renal function, plasma renin activity, and aldosterone concentration in mild-to-moderate essential hypertension.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:2

    Topics: Adult; Aldosterone; Clinical Trials as Topic; Female; Glomerular Filtration Rate; Hemodynamics; Huma

1987
Plasma renin activity does not predict the antihypertensive efficacy of chlorthalidone.
    European journal of clinical pharmacology, 1987, Volume: 33, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Double-Blind Method; E

1987
Acute and chronic ketanserin in essential hypertension: antihypertensive mechanisms and pharmacokinetics.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Electrocardiography; Female; Heart Rate; Humans;

1987
Haemodynamic (systemic and renal) and humoral interactions between nicardipine and domperidone in hypertensives.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1987, Volume: 5, Issue:5

    Topics: Adult; Aldosterone; Domperidone; Drug Interactions; Female; Glomerular Filtration Rate; Heart Rate;

1987
The effect of reduced alcohol consumption on blood pressure: a randomised, controlled, single blind study.
    Journal of human hypertension, 1987, Volume: 1, Issue:2

    Topics: Adult; Alcohol Drinking; Aldosterone; Blood Pressure; Clinical Trials as Topic; Epinephrine; Humans;

1987
Atenolol or propranolol in hypertensive patients poorly controlled on captopril and frusemide.
    Journal of human hypertension, 1987, Volume: 1, Issue:2

    Topics: Aged; Aldosterone; Atenolol; Blood Pressure; Captopril; Clinical Trials as Topic; Creatinine; Double

1987
Guanfacine as monotherapy for systemic hypertension.
    The American journal of cardiology, 1986, Mar-28, Volume: 57, Issue:9

    Topics: Adult; Aged; Aldosterone; Cholesterol; Clinical Trials as Topic; Double-Blind Method; Drug Evaluatio

1986
Effects of combined therapy with amiloride and hydrochlorothiazide on plasma and total body potassium, blood pressure, and the renin-angiotensin-aldosterone system in hypertensive patients.
    European journal of clinical pharmacology, 1986, Volume: 30, Issue:2

    Topics: Adult; Aged; Aldosterone; Amiloride; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Drug

1986
Prostaglandin E2 analogue elicits renal and hormonal compensatory mechanisms in human hypertension.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:6

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressu

1986
Selected mechanisms of diuretic-induced electrolyte changes.
    The American journal of cardiology, 1986, Jul-31, Volume: 58, Issue:2

    Topics: Aldosterone; Amiloride; Clinical Trials as Topic; Diuresis; Diuretics; Double-Blind Method; Humans;

1986
Hypokalemia in thiazide-treated systemic hypertension.
    The American journal of cardiology, 1986, Jul-31, Volume: 58, Issue:2

    Topics: Aldosterone; Amiloride; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydrochlorothia

1986
Neurohormonal responses to antihypertensive treatment with captopril or hydrochlorothiazide.
    Postgraduate medical journal, 1986, Volume: 62 Suppl 1

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Dopamine; Female; Humans; Hydrochlorothiazide; Hypert

1986
[Increased endogenous dopamine activity in diabetes mellitus. Inhibition of plasma renin activity, aldosterone and prolactin secretion].
    Fortschritte der Medizin, 1986, Dec-04, Volume: 104, Issue:45

    Topics: Aged; Aldosterone; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dopamine; Humans; Hypertensi

1986
The influence of ibuprofen, diclofenac and sulindac on the blood pressure lowering effect of hydrochlorothiazide.
    European journal of clinical pharmacology, 1987, Volume: 31, Issue:5

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Creatinine; Diclofenac; Drug The

1987
Potassium and norepinephrine- or angiotensin-mediated pressor control in pre-hypertension.
    Kidney international, 1987, Volume: 31, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Norepinephri

1987
Potassium supplementation in hypertensive patients with diuretic-induced hypokalemia.
    The New England journal of medicine, 1985, Mar-21, Volume: 312, Issue:12

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method;

1985
Effect of captopril and hydrochlorothiazide on the response to pressor agents in hypertensives.
    European journal of clinical pharmacology, 1985, Volume: 28, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Dru

1985
Effects of potassium on sodium balance, renin, noradrenaline and arterial pressure.
    Journal of hypertension, 1985, Volume: 3, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Condiments; Female; Heart Rate; Humans; Hyperten

1985
Interference on metabolism induced by muzolimine and chlorthalidone in type II hypertensive diabetics.
    Zeitschrift fur Kardiologie, 1985, Volume: 74 Suppl 2

    Topics: Aldosterone; Blood Glucose; Blood Pressure; Carbohydrate Metabolism; Chlorthalidone; Clinical Trials

1985
The sodium intake modifies the renin-aldosterone and blood pressure changes associated with moderately low energy diets.
    Acta medica Scandinavica, 1985, Volume: 218, Issue:2

    Topics: Aldosterone; Blood Pressure; Diet, Reducing; Diet, Sodium-Restricted; Humans; Hypertension; Male; Mi

1985
[Evaluation of the antihypertensive effect of capsule and tablet forms of nifedipine in moderate hypertension].
    Archives des maladies du coeur et des vaisseaux, 1985, Volume: 78 Spec No

    Topics: Aldosterone; Capsules; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertension; Nifedipi

1985
[Esmaloride--a new potassium neutral diuretic combination. Clinical pharmacologic properties].
    Fortschritte der Medizin, 1985, Feb-14, Volume: 103, Issue:6

    Topics: Aldosterone; Amiloride; Blood Glucose; Blood Pressure; Body Weight; Creatinine; Drug Combinations; F

1985
Effect of verapamil on renal plasma flow, glomerular filtration rate and plasma angiotensin II, aldosterone and arginine vasopressin in essential hypertension.
    European journal of clinical pharmacology, 1985, Volume: 29, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Blood Pressure; Body Weight; Female; Glome

1985
Beta-blockers and plasma renin activity in hypertension.
    British medical journal, 1974, Jan-12, Volume: 1, Issue:5897

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aldosterone; Benzothiadiazines; Blood Pressure; Crea

1974
High blood pressure and oral contraceptives. Changes in plasma renin and renin substrate and in aldosterone excretion.
    American journal of obstetrics and gynecology, 1968, Aug-15, Volume: 101, Issue:8

    Topics: Aldosterone; Angiotensin II; Clinical Trials as Topic; Contraceptives, Oral; Ethinyl Estradiol; Fema

1968
Effect of adrenocorticotropin on desoxycorticosterone, corticosterone and aldosterone excretion.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:8

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormo

1969
[Variations in the renin-angiotensin-aldosterone system and in the antidiuretic hormone induced within 5 days by a contraceptive drug. Rapid action of a contraceptive drug on the hormones controlling water and salt metabolism].
    La Presse medicale, 1970, Feb-21, Volume: 78, Issue:9

    Topics: Adult; Aldosterone; Angiotensin II; Clinical Trials as Topic; Contraceptives, Oral; Ethinyl Estradio

1970
18-Hydroxy-deoxycorticosterone in human hypertension.
    Circulation research, 1971, Volume: 28, Issue:5

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Blood Pressure; Catheteriz

1971
Propranolol therapy in essential hypertension. Observations on predictability of therapeutic response.
    International journal of clinical pharmacology, therapy and toxicology, 1974, Volume: 10, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aldosterone; Blood Pressure; Cardiac Output; Creatinine; Dose-Res

1974
Relation of age, diastolic pressure and known duration of hypertension to presence of low renin essential hypertension.
    The American journal of cardiology, 1973, Volume: 32, Issue:5

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aging; Aldosterone; Blood Pressure; Clinical Trials

1973
Treatment of low-renin essential hypertension. Comparison of spironolactone and a hydrochlorothiazide-triamterene combination.
    JAMA, 1974, Feb-04, Volume: 227, Issue:5

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine;

1974
[Clinical effect of a beta receptor blockader, oxprenolol, in hypertension--its relationship with renin-aldosterone activities].
    Horumon to rinsho. Clinical endocrinology, 1974, Volume: 22, Issue:9

    Topics: Adolescent; Adult; Aldosterone; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle

1974
Effects of acute and chronic administration of propranolol on blood pressure and plasma renin activity in hypertensive patients.
    Progress in biochemical pharmacology, 1974, Volume: 9

    Topics: Adolescent; Adult; Aldosterone; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Diet, S

1974
Total body potassium in long-term Lasix therapy.
    Scottish medical journal, 1974, Volume: 19 Suppl 1

    Topics: Aldosterone; Clinical Trials as Topic; Diuresis; Furosemide; Humans; Hydrochlorothiazide; Hypertensi

1974
A method for the simultaneous determination of the secretion rates of cortisol, 11-desoxycortisol, corticosterone, 11-desoxycorticosterone and aldosterone.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:4

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Carbon Isotopes; Child; Child, Pres

1969
The postural plasma renin activity response in essential hypertension and primary hyperaldosteronism.
    Acta medica Scandinavica, 1969, Volume: 186, Issue:4

    Topics: Adult; Aged; Aldosterone; Clinical Trials as Topic; Female; Humans; Hyperaldosteronism; Hypertension

1969

Other Studies

3835 other studies available for aldosterone and Hypertension

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A Chinese pedigree with glucocorticoid remediable aldosteronism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2021, Volume: 44, Issue:11

    Topics: Adult; Aldosterone; China; Cytochrome P-450 CYP11B2; Glucocorticoids; Humans; Hyperaldosteronism; Hy

2021
Correlation between kidney sodium and potassium handling and the renin-angiotensin-aldosterone system in children with hypertensive disorders.
    Pediatric nephrology (Berlin, Germany), 2022, Volume: 37, Issue:3

    Topics: Adolescent; Aldosterone; Blood Pressure; Creatinine; Cross-Sectional Studies; Female; Humans; Hypert

2022
The role of surgery in Conn's syndrome - a case of refractory hypertension secondary to an aldosterone secreting adenoma.
    South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie, 2021, Volume: 59, Issue:3

    Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Male

2021
The Effects of Verapamil, Hydralazine, and Doxazosin on Renin, Aldosterone, and the Ratio Thereof.
    Cardiovascular drugs and therapy, 2023, Volume: 37, Issue:2

    Topics: Aldosterone; Antihypertensive Agents; Doxazosin; Humans; Hydralazine; Hyperaldosteronism; Hypertensi

2023
Prevalence of primary aldosteronism in type 2 diabetes mellitus and hypertension: A prospective study from Western India.
    Clinical endocrinology, 2022, Volume: 96, Issue:4

    Topics: Adult; Aldosterone; Diabetes Mellitus, Type 2; Female; Humans; Hyperaldosteronism; Hypertension; Ind

2022
[A Case of Pseudohypoaldosteronism Type Ⅱ (PHA2) Caused by a Novel Mutation of
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2021, Volume: 52, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Adult; Aldosterone; Female; Humans; Hypertension; Microfilamen

2021
Hypertension with unilateral adrenal aldosterone and cortisol cosecreting adenoma: A case report.
    Journal of clinical hypertension (Greenwich, Conn.), 2021, Volume: 23, Issue:11

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Humans; Hydrocortisone; Hyperal

2021
Screening Rates for Primary Aldosteronism Among Individuals With Hypertension Plus Hypokalemia: A Population-Based Retrospective Cohort Study.
    Hypertension (Dallas, Tex. : 1979), 2022, Volume: 79, Issue:1

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperaldosteronism; Hypertension;

2022
First-in-Human Study of MANP: A Novel ANP (Atrial Natriuretic Peptide) Analog in Human Hypertension.
    Hypertension (Dallas, Tex. : 1979), 2021, Volume: 78, Issue:6

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Female; Humans; Hypertension; M

2021
Prediction of long-term biochemical cure in patients with unilateral primary hyperaldosteronism treated surgically based on the early post-operative plasma aldosterone value.
    Endocrine journal, 2022, Apr-28, Volume: 69, Issue:4

    Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Postoperative Period; Renin; R

2022
Evaluation of Intra-Renal Stiffness in Patients with Primary Aldosteronism.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2022, Volume: 29, Issue:1

    Topics: Adult; Aged; Aldosterone; Essential Hypertension; Female; Humans; Hyperaldosteronism; Hypertension;

2022
Genetic Predictors of Salt Sensitivity of Blood Pressure: The Additive Impact of 2 Hits in the Same Biological Pathway.
    Hypertension (Dallas, Tex. : 1979), 2021, Volume: 78, Issue:6

    Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Angiotensinogen; Blood Pressure; Estrogen Receptor be

2021
Fibrin clot properties and fibrinolysis in patients with endocrine hypertension due to aldosterone or catecholamines excess.
    Clinical endocrinology, 2022, Volume: 96, Issue:2

    Topics: Adrenal Gland Neoplasms; Aldosterone; Catecholamines; Fibrin; Fibrin Clot Lysis Time; Fibrinolysis;

2022
Plasma aldosterone concentration is associated with white matter lesions in patients with primary aldosteronism.
    Endocrine, 2022, Volume: 75, Issue:3

    Topics: Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin; Retrospectiv

2022
Higher aldosterone is associated with increased renal impairment risk in patients with hypertension and abnormal glucose metabolism: a longitudinal study.
    Journal of hypertension, 2022, 03-01, Volume: 40, Issue:3

    Topics: Aldosterone; Glomerular Filtration Rate; Glucose; Humans; Hypertension; Longitudinal Studies; Renal

2022
Aldosterone and renin concentrations were abnormally elevated in a cohort of normotensive pregnant women.
    Endocrine, 2022, Volume: 75, Issue:3

    Topics: Aldosterone; Blood Pressure; Female; Humans; Hypertension; Placenta; Pregnancy; Pregnancy Outcome; P

2022
Screening Rate for Primary Aldosteronism Among Patients With Apparent Treatment-Resistant Hypertension: Retrospective Analysis of Current Practice.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2022, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Mass Scree

2022
Suspected primary hyperreninism in a cat with malignant renal sarcoma and global renin-angiotensin-aldosterone system upregulation.
    Journal of veterinary internal medicine, 2022, Volume: 36, Issue:1

    Topics: Aldosterone; Animals; Cat Diseases; Cats; Hyperaldosteronism; Hypertension; Kidney Neoplasms; Male;

2022
Positive Association Between Plasma Aldosterone Concentration and White Matter Lesions in Patients With Hypertension.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Magnetic Resonance Imaging; Ma

2021
Enhanced performance of a modified diagnostic test of primary aldosteronism in patients with adrenal adenomas.
    European journal of endocrinology, 2022, Jan-06, Volume: 186, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Aldosterone; Dexamethasone; Female; Humans

2022
Th17/Treg imbalance in patients with primary hyperaldosteronism and resistant hypertension.
    Polish archives of internal medicine, 2022, 03-30, Volume: 132, Issue:3

    Topics: Aldosterone; Angiotensin II; Blood Pressure Monitoring, Ambulatory; Forkhead Transcription Factors;

2022
The neurobiology of childhood trauma-aldosterone and blood pressure changes in a community sample.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2022, Volume: 23, Issue:8

    Topics: Adverse Childhood Experiences; Aldosterone; Blood Pressure; Humans; Hypertension; Renin; Renin-Angio

2022
Salt-Sensitive Hypertension in GR
    International journal of molecular sciences, 2021, Dec-08, Volume: 22, Issue:24

    Topics: Adrenal Glands; Aldosterone; Animals; Corticosterone; Epoxide Hydrolases; Fatty Acids, Unsaturated;

2021
Letter to editor on "Thirty-six-month results of laparoscopic-based renal denervation plus unilateral laparoscopic adrenalectomy for the treatment of patients with resistant hypertension caused by unilateral aldosterone-producing Adenoma".
    Journal of clinical hypertension (Greenwich, Conn.), 2022, Volume: 24, Issue:2

    Topics: Adenoma; Adrenalectomy; Aldosterone; Denervation; Humans; Hyperaldosteronism; Hypertension; Laparosc

2022
Screening for primary aldosteronism in the diabetic population: a cohort study.
    Internal medicine journal, 2023, Volume: 53, Issue:5

    Topics: Aldosterone; Cohort Studies; Diabetes Mellitus, Type 2; Humans; Hyperaldosteronism; Hypertension; Ma

2023
Higher Plasma Aldosterone Concentrations Are Associated With Elevated Risk of Aortic Dissection and Aneurysm: a Case-Control Study.
    Hypertension (Dallas, Tex. : 1979), 2022, Volume: 79, Issue:4

    Topics: Aldosterone; Aortic Dissection; Case-Control Studies; Female; Humans; Hyperaldosteronism; Hypertensi

2022
Salt Sensitivity of Blood Pressure and Aldosterone: Interaction Between the Lysine-specific Demethylase 1 Gene, Sex, and Age.
    The Journal of clinical endocrinology and metabolism, 2022, 04-19, Volume: 107, Issue:5

    Topics: Aldosterone; Animals; Blood Pressure; Epigenesis, Genetic; Estrogens; Female; Histone Demethylases;

2022
Apparent mineralocorticoid excess: A diagnosis beyond classical causes of severe hypertension in a child.
    Blood pressure monitoring, 2022, Jun-01, Volume: 27, Issue:3

    Topics: Aldosterone; Amiloride; Blood Pressure; Child, Preschool; Female; Humans; Hypertension; Hypokalemia;

2022
MANP (M-Atrial Natriuretic Peptide) Reduces Blood Pressure and Furosemide-Induced Increase in Aldosterone in Hypertension.
    Hypertension (Dallas, Tex. : 1979), 2022, Volume: 79, Issue:4

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Furosemide; Guanosine M

2022
[Diagnosis and therapy of primary aldosteronism: new aspects].
    Deutsche medizinische Wochenschrift (1946), 2022, Volume: 147, Issue:3

    Topics: Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hyperplasia; Hypert

2022
Establishing Reference Ranges for Aldosterone, Renin and Aldosterone-to-Renin Ratio for Women in the Third-Trimester of Pregnancy.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2022, Volume: 130, Issue:4

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Pregnancy; Pregnancy Trimester

2022
Syndromes of Pseudo-Hyperaldosteronism.
    Clinical journal of the American Society of Nephrology : CJASN, 2022, Volume: 17, Issue:4

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Renin; Syndrome

2022
Screening for primary aldosteronism is underutilised in patients with chronic kidney disease.
    Journal of nephrology, 2022, Volume: 35, Issue:6

    Topics: Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Renal Insufficiency, Chroni

2022
Renin, aldosterone, the aldosterone-to-renin ratio, and incident hypertension among normotensive subjects from the general population.
    Cardiovascular research, 2023, 03-17, Volume: 119, Issue:1

    Topics: Aldosterone; Biomarkers; Blood Pressure; Female; Humans; Hypertension; Male; Renin

2023
Detecting primary aldosteronism in Australian primary care: a prospective study.
    The Medical journal of Australia, 2022, 05-02, Volume: 216, Issue:8

    Topics: Adult; Aldosterone; Australia; Humans; Hyperaldosteronism; Hypertension; Primary Health Care; Prospe

2022
Renal artery occlusive disease, renin-angiotensin-aldosterone, inflammation, and refractory arterial hypertension, a half-century's perspective.
    Journal of vascular surgery, 2022, Volume: 76, Issue:1

    Topics: Aldosterone; Angiotensin II; Angiotensins; Blood Pressure; Humans; Hypertension; Inflammation; Renal

2022
Circulating renin-angiotensin-aldosterone system activity in cats with systemic hypertension or cardiomyopathy.
    Journal of veterinary internal medicine, 2022, Volume: 36, Issue:3

    Topics: Aldosterone; Amlodipine; Animals; Biomarkers; Cardiomyopathies; Cat Diseases; Cats; Furosemide; Hype

2022
Plasma aldosterone to renin ratio for the detection of primary aldosteronism in patients with drug-resistant hypertension.
    The Medical journal of Australia, 2022, 05-02, Volume: 216, Issue:8

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

2022
Impact of renin-angiotensin-aldosterone-system inhibitor drugs on mortality in patients with atrial fibrillation and hypertension.
    BMC cardiovascular disorders, 2022, 04-01, Volume: 22, Issue:1

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensin

2022
Machine learning-based models for predicting clinical outcomes after surgery in unilateral primary aldosteronism.
    Scientific reports, 2022, 04-06, Volume: 12, Issue:1

    Topics: Adrenalectomy; Aldosterone; Antihypertensive Agents; Cross-Sectional Studies; Humans; Hyperaldostero

2022
Case Report: Primary Aldosteronism Due to Bilateral Aldosterone-Producing Micronodules With HISTALDO Classical and Contralateral Non-Classical Pathology.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adenoma; Adrenocortical Adenoma; Aldosterone; Cytochrome P-450 CYP11B2; Female; G Protein-Coupled In

2022
Early Renin Recovery After Adrenalectomy in Aldosterone-Producing Adenomas: A Prospective Study.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2022, Volume: 54, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adrenocorticotropic Hormone

2022
A pilot study to evaluate the erythrocyte glycocalyx sensitivity to sodium as a marker for cellular salt sensitivity in hypertension.
    Journal of human hypertension, 2023, Volume: 37, Issue:4

    Topics: Aldosterone; Blood Pressure; Erythrocytes; Essential Hypertension; Female; Glycocalyx; Humans; Hyper

2023
Japan Endocrine Society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021.
    Endocrine journal, 2022, Apr-28, Volume: 69, Issue:4

    Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Japan; Mineralocorticoid Recep

2022
Primary aldosteronism.
    BMJ (Clinical research ed.), 2022, 04-20, Volume: 377

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

2022
Covid-19 associated reduction in hypertension-related diagnostic and therapeutic procedures in Excellence Centers of the European Society of Hypertension.
    Blood pressure, 2022, Volume: 31, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Catecho

2022
The use of renin angiotensin aldosterone system inhibitors may be associated with decreased mortality after cancer surgery.
    Scientific reports, 2022, 04-27, Volume: 12, Issue:1

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hyper

2022
Creation of a quick and sensitive fluorescent immunosensor for detecting the mineralocorticoid steroid hormone aldosterone.
    The Journal of steroid biochemistry and molecular biology, 2022, Volume: 221

    Topics: Aldosterone; Biosensing Techniques; Humans; Hypertension; Immunoassay; Mineralocorticoids

2022
Primary Aldosteronism More Prevalent in Patients With Cardioembolic Stroke and Atrial Fibrillation.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Aldosterone; Atrial Fibrillation; Embolic Stroke; Humans; Hyperaldosteronism; Hypertension; Renin; S

2022
Higher plasma renin activity is associated with increased kidney damage risk in patients with hypertension and glucose metabolic disorders.
    Journal of clinical hypertension (Greenwich, Conn.), 2022, Volume: 24, Issue:6

    Topics: Aldosterone; Glucose Metabolism Disorders; Humans; Hypertension; Kidney; Proteinuria; Renal Insuffic

2022
Association of Renin-Angiotensin-Aldosterone Inhibitors with COVID-19 Infection and Disease Severity among Individuals with Hypertension.
    The Israel Medical Association journal : IMAJ, 2022, Volume: 24, Issue:5

    Topics: Aldosterone; Angiotensins; Antihypertensive Agents; COVID-19 Drug Treatment; Humans; Hypertension; M

2022
Divergent Characteristics of T-Cell Receptor Repertoire Between Essential Hypertension and Aldosterone-Producing Adenoma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adenoma; Aldosterone; Essential Hypertension; Humans; Hypertension; Receptors, Antigen, T-Cell; Reni

2022
Hypertension Resolution after Laparoscopic Adrenal Tumor Resection in Patients of Adrenal Incidentaloma with Normal Hormone Levels.
    Urologia internationalis, 2023, Volume: 107, Issue:2

    Topics: Adrenal Gland Neoplasms; Aldosterone; Female; Humans; Hypertension; Laparoscopy; Male; Retrospective

2023
Clinical, biochemical, and miRNA profile of subjects with positive screening of primary aldosteronism and nonclassic apparent mineralocorticoid excess.
    Endocrine, 2022, Volume: 77, Issue:2

    Topics: Aldosterone; Cortisone; Cross-Sectional Studies; Humans; Hyperaldosteronism; Hypertension; Lipocalin

2022
Prevalence and clinical characteristics of primary aldosteronism in a tertiary-care center in Korea.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2022, Volume: 45, Issue:9

    Topics: Adult; Aldosterone; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hyperaldosteronism; Hyper

2022
'I can't understand why others don't screen more': a qualitative study exploring why Australian general practitioners screen for primary aldosteronism.
    BMJ open, 2022, 06-13, Volume: 12, Issue:6

    Topics: Aldosterone; Antihypertensive Agents; Australia; Female; General Practitioners; Humans; Hyperaldoste

2022
Liddle syndrome misdiagnosed as primary aldosteronism is caused by inaccurate aldosterone-rennin detection while a novel
    Blood pressure, 2022, Volume: 31, Issue:1

    Topics: Adult; Aldosterone; Chymosin; Diagnostic Errors; Epithelial Sodium Channels; Female; Humans; Hyperal

2022
Ambulatory fludrocortisone suppression test in the diagnosis of primary aldosteronism: Safety, accuracy and cost-effectiveness.
    Clinical endocrinology, 2022, Volume: 97, Issue:6

    Topics: Aldosterone; Cost-Benefit Analysis; Fludrocortisone; Humans; Hyperaldosteronism; Hypertension; Renin

2022
Association of cardiovascular disease risk and changes in renin levels by mineralocorticoid receptor antagonists in patients with primary aldosteronism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2022, Volume: 45, Issue:9

    Topics: Aldosterone; Cardiovascular Diseases; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Re

2022
Comparison of Echocardiographic Changes Between Surgery and Medication Treatment in Patients With Primary Aldosteronism.
    Journal of the American Heart Association, 2022, 07-05, Volume: 11, Issue:13

    Topics: Aldosterone; Echocardiography; Humans; Hyperaldosteronism; Hypertension; Hypertrophy, Left Ventricul

2022
Reliability Analysis of a Functional Diagnostic Test for Primary Hyperaldosteronism Based on Data Analysis.
    Computational intelligence and neuroscience, 2022, Volume: 2022

    Topics: Aldosterone; Data Analysis; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hypertension; Ren

2022
Hunting for protective drugs at the break of a pandemic: Causal inference from hospital data.
    Statistical methods in medical research, 2022, Volume: 31, Issue:9

    Topics: Aldosterone; COVID-19 Drug Treatment; Hospitals; Humans; Hypertension; Pandemics; Protective Agents;

2022
Primary Aldosteronism Screening Rates Differ with Sex, Race, and Comorbidities.
    Journal of the American Heart Association, 2022, 07-19, Volume: 11, Issue:14

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Mass Screen

2022
Upregulation of Mineralocorticoid Receptor Contributes to Development of Salt-Sensitive Hypertension after Ischemia-Reperfusion Injury in Rats.
    International journal of molecular sciences, 2022, Jul-15, Volume: 23, Issue:14

    Topics: Aldosterone; Animals; Blood Pressure; Hypertension; Kidney; Rats; Receptors, Mineralocorticoid; Repe

2022
The metabolic phenotype of patients with primary aldosteronism: impact of subtype and sex - a multicenter-study of 3566 Caucasian and Asian subjects.
    European journal of endocrinology, 2022, Sep-01, Volume: 187, Issue:3

    Topics: Adenoma; Aldosterone; Diabetes Mellitus, Type 2; Female; Humans; Hydrocortisone; Hyperaldosteronism;

2022
Relationship Between Risks for Obstructive Sleep Apnea, Resistant Hypertension, and Aldosterone Among African American Adults in the Jackson Heart Study.
    American journal of hypertension, 2022, 10-03, Volume: 35, Issue:10

    Topics: Adult; Aldosterone; Black or African American; Cross-Sectional Studies; Humans; Hypertension; Longit

2022
Chinese normotensive and essential hypertensive reference intervals for plasma aldosterone and renin activity by liquid chromatography-tandem mass spectrometry.
    Clinical chemistry and laboratory medicine, 2022, 09-27, Volume: 60, Issue:10

    Topics: Aged; Aldosterone; Blood Pressure; China; Chromatography, Liquid; Humans; Hypertension; Renin; Tande

2022
Clinical and biochemical predictors and predictive model of primary aldosteronism.
    PloS one, 2022, Volume: 17, Issue:8

    Topics: Adrenal Gland Neoplasms; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Middle Aged;

2022
Pseudohypoaldosteronism associated with hypertrophic cardiomyopathy, hypertension and thrombocytosis due to mutation in the ELAC2 gene: a case report.
    Journal of pediatric endocrinology & metabolism : JPEM, 2022, Nov-25, Volume: 35, Issue:11

    Topics: Aldosterone; Cardiomyopathy, Hypertrophic; Child; Humans; Hypertension; Mutation; Neoplasm Proteins;

2022
Effect of Angiotensin receptor blockade on Plasma Osmolality and Neurohumoral Responses to High Environmental Temperature in Rats Fed a High Salt Diet.
    Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria, 2021, Dec-31, Volume: 36, Issue:2

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit

2021
Anti-Hypertensive Effects of Anthocyanins from Hibiscus sabdarifa Calyx on the Renin-Angiotensin-Aldoslestrone System in Wistar Rats.
    Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria, 2022, Jun-30, Volume: 37, Issue:1

    Topics: Aldosterone; Animals; Anthocyanins; Antihypertensive Agents; Blood Pressure; Captopril; Hibiscus; Hy

2022
Variability of aldosterone, renin and the aldosterone-to-renin ratio in hypertensive patients without primary aldosteronism.
    Journal of hypertension, 2022, 11-01, Volume: 40, Issue:11

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Reproducibility of Results

2022
Two cases of aldosterone and cortisol producing adenoma with different histopathological features: A case report.
    Medicine, 2022, Aug-12, Volume: 101, Issue:32

    Topics: Adenoma; Aldosterone; Cytochrome P-450 CYP11B2; Humans; Hydrocortisone; Hyperaldosteronism; Hyperten

2022
Aldosterone breakthrough as a clue to the physiological importance of paracrine regulation of aldosterone secretion.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2022, Volume: 45, Issue:11

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Humans; Hypertension

2022
A case of malignant nephrosclerosis occurring with serum renin in the normal range.
    CEN case reports, 2023, Volume: 12, Issue:1

    Topics: Adult; Aldosterone; Humans; Hypertension; Male; Nephrosclerosis; Reference Values; Renin

2023
Genetic screening of hypertensive patients with aldosterone hypersecretion under conditions of stress.
    Hormones (Athens, Greece), 2022, Volume: 21, Issue:4

    Topics: Aldosterone; Genetic Testing; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor A

2022
Primary aldosteronism caused by a pI157S somatic
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Child; Female; G

2022
Prevalence of Primary Aldosteronism in Newly Diagnosed Hypertensive Patients in Primary Care.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2022, Volume: 130, Issue:12

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Prevalence; Primary Health Care;

2022
Impact of dedicated multidisciplinary service on patient selection and outcomes for surgical treatment of primary aldosteronism.
    Surgery, 2022, Volume: 172, Issue:6

    Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Patient Selection; Retrospecti

2022
Circulating Plasma Concentrations of ACE2 in Primary Aldosteronism and Cardiovascular Outcomes.
    The Journal of clinical endocrinology and metabolism, 2022, 11-25, Volume: 107, Issue:12

    Topics: Adrenalectomy; Aldosterone; Angiotensin-Converting Enzyme 2; Cardiovascular Diseases; Essential Hype

2022
Associated factors and effects of comorbid atrial fibrillation in hypertensive patients due to primary aldosteronism.
    Journal of human hypertension, 2023, Volume: 37, Issue:9

    Topics: Adult; Aldosterone; Atrial Fibrillation; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; M

2023
Aldosterone, Renin, and Aldosterone-to-Renin Ratio Variability in Screening for Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2022, 12-17, Volume: 108, Issue:1

    Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin; Retrospecti

2022
Primary aldosteronism presenting as embolic myocardial infarction.
    Neuro endocrinology letters, 2022, Sep-16, Volume: 43, Issue:3

    Topics: Adrenal Glands; Aldosterone; Arrhythmias, Cardiac; Embolism; Female; Humans; Hyperaldosteronism; Hyp

2022
Green tea could improve elderly hypertension by modulating arterial stiffness, the activity of the renin/angiotensin/aldosterone axis, and the sodium-potassium pumps in old male rats.
    Journal of food biochemistry, 2022, Volume: 46, Issue:12

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Hypertension; Lipids; M

2022
Galectin-7 dysregulates renin-angiotensin-aldosterone and NADPH oxide synthase pathways in preeclampsia.
    Pregnancy hypertension, 2022, Volume: 30

    Topics: Aldosterone; Angiotensins; Animals; Female; Galectins; Humans; Hypertension; Mice; NADP; NADPH Oxida

2022
Screening for primary aldosteronism: The "PA" Shiny app.
    Annals of clinical biochemistry, 2022, Volume: 59, Issue:6

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Mobile Applications; Renin

2022
Inconsistencies in laboratory investigations of hypertension in a young woman taking ethinylestradiol/drospirenone association.
    Acta clinica Belgica, 2023, Volume: 78, Issue:4

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Renin

2023
Unilateral Adrenalectomy for Primary Aldosteronism Due to Bilateral Adrenal Disease Can Result in Resolution of Hypokalemia and Amelioration of Hypertension.
    World journal of surgery, 2023, Volume: 47, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyperald

2023
Catheter-based adrenal ablation: an alternative therapy for patients with aldosterone-producing adenoma.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:1

    Topics: Adenoma; Adrenalectomy; Aldosterone; Catheters; Humans; Hyperaldosteronism; Hypertension; Retrospect

2023
Importance of dietary salt restriction for patients with primary aldosteronism during treatment with mineralocorticoid receptor antagonists: The potential importance of post-treatment plasma renin levels.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:1

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor An

2023
Higher plasma aldosterone is associated with increased risk of cardiovascular events in hypertensive patients with suspected OSA: UROSAH data.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Cardiovascular Diseases; Humans; Hyperaldos

2022
[New clinical opportunities for mineralocorticoid receptor antagonists: focus on antifibrotic effects].
    Terapevticheskii arkhiv, 2021, Sep-15, Volume: 93, Issue:9

    Topics: Aldosterone; COVID-19 Drug Treatment; Eplerenone; Humans; Hypertension; Mineralocorticoid Receptor A

2021
[Primary hyperaldosteronism: indications for screening].
    Terapevticheskii arkhiv, 2022, Jan-15, Volume: 94, Issue:1

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Renin

2022
Mutagenesis of the cleavage site of (pro)renin receptor abrogates aldosterone-salt-induced hypertension and renal injury in mice.
    American journal of physiology. Renal physiology, 2023, 01-01, Volume: 324, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Hypertension; Kidney; Mice; Mineralocorticoids; Mutagenesis; P

2023
Salt-Losing Syndrome in a Girl with Type I and II Pseudohypoaldosteronism.
    The American journal of case reports, 2022, Oct-28, Volume: 23

    Topics: Acidosis; Aldosterone; Female; Humans; Hyperkalemia; Hypertension; Hyponatremia; Infant; Pseudohypoa

2022
Lysine-specific demethylase 1 deficiency modifies aldosterone synthesis in a sex-specific manner.
    The Journal of endocrinology, 2023, Jan-01, Volume: 256, Issue:1

    Topics: Aldosterone; Animals; Blood Pressure; Female; Hypertension; Lysine; Male; Mice; Zona Glomerulosa

2023
Implication of MR Activity in Posttreatment Arterial Stiffness Reversal in Patients With Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2023, 02-15, Volume: 108, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Pulse Wave Analysis; Renin; Vascular Stiffnes

2023
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
    Cardiovascular and interventional radiology, 2023, Volume: 46, Issue:1

    Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype

2023
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
    Cardiovascular and interventional radiology, 2023, Volume: 46, Issue:1

    Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype

2023
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
    Cardiovascular and interventional radiology, 2023, Volume: 46, Issue:1

    Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype

2023
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
    Cardiovascular and interventional radiology, 2023, Volume: 46, Issue:1

    Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype

2023
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
    Cardiovascular and interventional radiology, 2023, Volume: 46, Issue:1

    Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype

2023
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
    Cardiovascular and interventional radiology, 2023, Volume: 46, Issue:1

    Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype

2023
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
    Cardiovascular and interventional radiology, 2023, Volume: 46, Issue:1

    Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype

2023
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
    Cardiovascular and interventional radiology, 2023, Volume: 46, Issue:1

    Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype

2023
Cost Analysis of Radiofrequency Ablation for Adrenal Adenoma in Patients with Primary Aldosteronism and Hypertension: Results from the ADERADHTA Pilot Study and Comparison with Surgical Adrenalectomy.
    Cardiovascular and interventional radiology, 2023, Volume: 46, Issue:1

    Topics: Adenoma; Adrenalectomy; Adult; Aldosterone; Catheter Ablation; Costs and Cost Analysis; Humans; Hype

2023
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
    The Journal of clinical endocrinology and metabolism, 2023, 04-13, Volume: 108, Issue:5

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin

2023
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
    The Journal of clinical endocrinology and metabolism, 2023, 04-13, Volume: 108, Issue:5

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin

2023
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
    The Journal of clinical endocrinology and metabolism, 2023, 04-13, Volume: 108, Issue:5

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin

2023
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
    The Journal of clinical endocrinology and metabolism, 2023, 04-13, Volume: 108, Issue:5

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin

2023
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
    The Journal of clinical endocrinology and metabolism, 2023, 04-13, Volume: 108, Issue:5

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin

2023
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
    The Journal of clinical endocrinology and metabolism, 2023, 04-13, Volume: 108, Issue:5

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin

2023
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
    The Journal of clinical endocrinology and metabolism, 2023, 04-13, Volume: 108, Issue:5

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin

2023
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
    The Journal of clinical endocrinology and metabolism, 2023, 04-13, Volume: 108, Issue:5

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin

2023
Intra-individual Variability of Serum Aldosterone and Implications for Primary Aldosteronism Screening.
    The Journal of clinical endocrinology and metabolism, 2023, 04-13, Volume: 108, Issue:5

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Renin

2023
An explorative epigenome-wide association study of plasma renin and aldosterone concentration in a Ghanaian population: the RODAM study.
    Clinical epigenetics, 2022, 12-01, Volume: 14, Issue:1

    Topics: Aldosterone; DNA Methylation; Epigenesis, Genetic; Epigenome; Ghana; Humans; Hypertension; Nerve Tis

2022
An explorative epigenome-wide association study of plasma renin and aldosterone concentration in a Ghanaian population: the RODAM study.
    Clinical epigenetics, 2022, 12-01, Volume: 14, Issue:1

    Topics: Aldosterone; DNA Methylation; Epigenesis, Genetic; Epigenome; Ghana; Humans; Hypertension; Nerve Tis

2022
An explorative epigenome-wide association study of plasma renin and aldosterone concentration in a Ghanaian population: the RODAM study.
    Clinical epigenetics, 2022, 12-01, Volume: 14, Issue:1

    Topics: Aldosterone; DNA Methylation; Epigenesis, Genetic; Epigenome; Ghana; Humans; Hypertension; Nerve Tis

2022
An explorative epigenome-wide association study of plasma renin and aldosterone concentration in a Ghanaian population: the RODAM study.
    Clinical epigenetics, 2022, 12-01, Volume: 14, Issue:1

    Topics: Aldosterone; DNA Methylation; Epigenesis, Genetic; Epigenome; Ghana; Humans; Hypertension; Nerve Tis

2022
Primary aldosteronism is a clinical issue that should not be underestimated anymore.
    Journal of endocrinological investigation, 2023, Volume: 46, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

2023
Primary aldosteronism is a clinical issue that should not be underestimated anymore.
    Journal of endocrinological investigation, 2023, Volume: 46, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

2023
Primary aldosteronism is a clinical issue that should not be underestimated anymore.
    Journal of endocrinological investigation, 2023, Volume: 46, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

2023
Primary aldosteronism is a clinical issue that should not be underestimated anymore.
    Journal of endocrinological investigation, 2023, Volume: 46, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

2023
A case report of a young boy with low renin and high aldosterone levels induced by Liddle syndrome who was previously misdiagnosed with primary aldosteronism.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Feb-23, Volume: 36, Issue:2

    Topics: Adolescent; Aldosterone; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; L

2023
A case report of a young boy with low renin and high aldosterone levels induced by Liddle syndrome who was previously misdiagnosed with primary aldosteronism.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Feb-23, Volume: 36, Issue:2

    Topics: Adolescent; Aldosterone; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; L

2023
A case report of a young boy with low renin and high aldosterone levels induced by Liddle syndrome who was previously misdiagnosed with primary aldosteronism.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Feb-23, Volume: 36, Issue:2

    Topics: Adolescent; Aldosterone; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; L

2023
A case report of a young boy with low renin and high aldosterone levels induced by Liddle syndrome who was previously misdiagnosed with primary aldosteronism.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Feb-23, Volume: 36, Issue:2

    Topics: Adolescent; Aldosterone; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; L

2023
The promise of selective aldosterone synthase inhibition for the management of resistant hypertension.
    European heart journal, 2023, 02-21, Volume: 44, Issue:8

    Topics: Aldosterone; Blood Pressure; Cytochrome P-450 CYP11B2; Humans; Hypertension

2023
Behavior of the renal kallikrein in spontaneously hypertensive rats: Influence of sexual hormones and aldosterone-sensitive distal nephron ion channels.
    Peptides, 2023, Volume: 160

    Topics: Aldosterone; Animals; Epithelial Sodium Channels; Female; Hypertension; Ion Channels; Kallikreins; K

2023
Fatty acids as a direct regulator of aldosterone hypersecretion.
    Molecular and cellular endocrinology, 2023, 02-05, Volume: 561

    Topics: Aldosterone; Cytochrome P-450 CYP11B2; Fatty Acids; Humans; Hyperaldosteronism; Hypertension; Palmit

2023
Effect of Metabolic Adaptation by Voluntary Running Wheel Activity and Aldosterone Inhibition on Renal Function in Female Spontaneously Hypertensive Rats.
    Cells, 2022, 12-07, Volume: 11, Issue:24

    Topics: Aldosterone; Animals; Body Weight; Female; Hypertension; Kidney; Motor Activity; Proprotein Converta

2022
The selective aldosterone synthase inhibitor Baxdrostat significantly lowers blood pressure in patients with resistant hypertension.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Aldosterone; Blood Pressure; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Humans; Hypertension; Mine

2022
Serum aldosterone effect on left ventricular structure and diastolic function in essential hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2023, Volume: 25, Issue:2

    Topics: Aldosterone; Diastole; Echocardiography; Essential Hypertension; Female; Humans; Hypertension; Hyper

2023
Effect of Oral Contraception on Screening Tests for Primary Aldosteronism: A 10-Year Longitudinal Study.
    The Journal of clinical endocrinology and metabolism, 2023, Jun-16, Volume: 108, Issue:7

    Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Longitudinal Studi

2023
Advances in Medical Treatment of Primary Aldosteronism.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2023, Mar-31, Volume: 38, Issue:1

    Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Ant

2023
Diabetes mellitus is associated with more adverse non-hemodynamic left ventricular remodeling and less recovery in patients with primary aldosteronism.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2023, Volume: 71, Issue:2

    Topics: Aldosterone; Diabetes Mellitus; Echocardiography; Humans; Hyperaldosteronism; Hypertension; Hypertro

2023
New CT Scan Distinguishes Primary Aldosteronism Subtypes.
    JAMA, 2023, 02-14, Volume: 329, Issue:6

    Topics: Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Tomography, X-Ray Computed

2023
Acute psychotic episode inaugurating a primary hyperaldosteronism: a case report.
    The Pan African medical journal, 2022, Volume: 43

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypok

2022
The DOCA-Salt Model of Hypertension for Studies of Cerebrovascular Function, Stroke, and Brain Health.
    Methods in molecular biology (Clifton, N.J.), 2023, Volume: 2616

    Topics: Acetates; Aldosterone; Brain; Desoxycorticosterone Acetate; Humans; Hypertension; Renin-Angiotensin

2023
The effect of age, sex and BMI on the aldosterone-to-renin ratio in essential hypertensive individuals.
    Journal of hypertension, 2023, 04-01, Volume: 41, Issue:4

    Topics: Aldosterone; Body Mass Index; Female; Humans; Hyperaldosteronism; Hypertension; Male; Renin

2023
Decreasing the Effects of Aldosterone in Resistant Hypertension - A Success Story.
    The New England journal of medicine, 2023, 02-02, Volume: 388, Issue:5

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension

2023
Aldosterone and Treatment-Resistant Hypertension.
    The New England journal of medicine, 2023, 02-02, Volume: 388, Issue:5

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Monit

2023
Malignant Hypertension and Bilateral Primary Aldosteronism.
    Internal medicine (Tokyo, Japan), 2023, Sep-15, Volume: 62, Issue:18

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Mineralocorticoid Re

2023
Coexistence of Pheochromocytoma and Primary Aldosteronism due to Multiple Aldosterone-producing Micronodules in the Ipsilateral Adrenal Gland.
    Internal medicine (Tokyo, Japan), 2023, Sep-15, Volume: 62, Issue:18

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Female; Humans; Hyperaldosteron

2023
International multicenter survey on screening and confirmatory testing in primary aldosteronism.
    European journal of endocrinology, 2023, Jan-10, Volume: 188, Issue:1

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Surveys and Questionnaires

2023
Association of objective and subjective parameters of obstructive sleep apnea with plasma aldosterone concentration in 2,066 hypertensive and 25,368 general population.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Male; Sleep; Sleep Apnea, Obstructive

2022
Aldosterone Synthase Inhibitors and the Treatment of Essential Hypertension.
    The Journal of clinical endocrinology and metabolism, 2023, Jul-14, Volume: 108, Issue:8

    Topics: Aldosterone; Cytochrome P-450 CYP11B2; Essential Hypertension; Humans; Hyperaldosteronism; Hypertens

2023
Effect of the interaction between the visceral-to-subcutaneous fat ratio and aldosterone on cardiac function in patients with primary aldosteronism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:5

    Topics: Aldosterone; Cardiovascular Diseases; Humans; Hyperaldosteronism; Hypertension; Intra-Abdominal Fat;

2023
The renin-angiotensin-aldosterone system: a new look at an old system.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:4

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin; Renin-Angiotensin System

2023
Association of Aldosterone with Mortality in the General Population.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2023, Volume: 131, Issue:5

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Humans; Hypertension; Inflammatio

2023
Impact of a change to a novel chemiluminescent immunoassay for measuring plasma aldosterone on the diagnosis of primary aldosteronism.
    Endocrine journal, 2023, May-29, Volume: 70, Issue:5

    Topics: Aldosterone; Captopril; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Immunoassay; Renin; R

2023
Pitfalls in the diagnosis and treatment of a hypertensive patient with unilateral primary aldosteronism and contralateral pheochromocytoma: a case report.
    BMC endocrine disorders, 2023, Feb-16, Volume: 23, Issue:1

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Female; Humans; Hyperaldosteron

2023
RAS-challenge as a first-look test for detection of primary aldosteronism in patients with treatment-resistant hypertension.
    Blood pressure, 2023, Volume: 32, Issue:1

    Topics: Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin

2023
ER ribosomal-binding protein 1 regulates blood pressure and potassium homeostasis by modulating intracellular renin trafficking.
    Journal of biomedical science, 2023, Feb-19, Volume: 30, Issue:1

    Topics: Aldosterone; Aluminum Oxide; Animals; Blood Pressure; Carrier Proteins; Genome-Wide Association Stud

2023
Renin, Aldosterone, and Cortisol in Pregnancy-Induced Hypertension.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2023, Volume: 131, Issue:4

    Topics: Aldosterone; Female; Humans; Hydrocortisone; Hypertension; Hypertension, Pregnancy-Induced; Potassiu

2023
Aldosterone breakthrough from a pharmacological perspective.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:5

    Topics: Aldosterone; Humans; Hypertension; Renin; Renin-Angiotensin System

2023
A hyperaldosteronism subtypes predictive model using ensemble learning.
    Scientific reports, 2023, 02-21, Volume: 13, Issue:1

    Topics: Adenoma; Aldosterone; Cross-Sectional Studies; Humans; Hyperaldosteronism; Hypertension; Potassium;

2023
Smooth Muscle Mineralocorticoid Receptor Promotes Hypertension After Preeclampsia.
    Circulation research, 2023, 03-17, Volume: 132, Issue:6

    Topics: Aldosterone; Animals; Female; Humans; Hypertension; Mice; Muscle, Smooth; Pre-Eclampsia; Pregnancy;

2023
[Noninvasive stratification of primary aldosteronism: a glimpse of latest updates].
    Zhonghua nei ke za zhi, 2023, Mar-01, Volume: 62, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

2023
Screening for Primary Aldosteronism Among Hypertensive Adults with Obstructive Sleep Apnea: A Retrospective Population-Based Study.
    American journal of hypertension, 2023, 06-15, Volume: 36, Issue:7

    Topics: Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Ontario; Renin; Retrospec

2023
Visceral fat: a bad companion for mineralocorticoid receptor overactivation.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:5

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Intra-Abdominal Fat; Receptors, Mineralocorti

2023
Usefulness of Alternative Therapy with Hydrocortisone in the Postoperative Management of Severe Primary Aldosteronism.
    Internal medicine (Tokyo, Japan), 2023, Oct-15, Volume: 62, Issue:20

    Topics: Adrenalectomy; Aldosterone; Humans; Hydrocortisone; Hyperaldosteronism; Hyperkalemia; Hypertension;

2023
    Revue medicale suisse, 2023, 03-08, Volume: 19, Issue:817

    Topics: Aldosterone; Humans; Hypertension

2023
An Abbreviated History of Aldosterone Metabolism, Current and Future Challenges.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2023, Volume: 131, Issue:7-08

    Topics: Aldosterone; Animals; Glucuronides; Glucuronosyltransferase; Hyperaldosteronism; Hypertension

2023
Early Implementation of Aldosterone-Targeted Therapy in Patients With Hypertension.
    Circulation, 2023, 03-28, Volume: 147, Issue:13

    Topics: Aldosterone; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Receptors, Mineralocortic

2023
Blood Levels of Angiotensinogen and Hypertension in the Multi-Ethnic Study of Atherosclerosis (MESA).
    Journal of the American College of Cardiology, 2023, 04-04, Volume: 81, Issue:13

    Topics: Adult; Aldosterone; Angiotensinogen; Atherosclerosis; Blood Pressure; Female; Humans; Hypertension;

2023
Efficacy of Antihypertensive Drugs of Different Classes After Renal Denervation in Spontaneously Hypertensive Rats.
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:6

    Topics: Aldosterone; Amlodipine; Animals; Antihypertensive Agents; Bisoprolol; Blood Pressure; Cardiomyopath

2023
Reference intervals for LC-MS /MS measurements of plasma renin activity, aldosterone, angiotensin II, and 24-hour urinary aldosterone in Northern Chinese Han population.
    Clinica chimica acta; international journal of clinical chemistry, 2023, Mar-15, Volume: 543

    Topics: Aldosterone; Angiotensin II; Chromatography, Liquid; East Asian People; Healthy Volunteers; Humans;

2023
Renal Artery Stenosis Complicated with Primary Aldosteronism.
    International heart journal, 2023, Volume: 64, Issue:2

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Renal Artery Obstruction; Reni

2023
Decoding Hypertension Through Primary Aldosteronism.
    Circulation, 2023, 04-04, Volume: 147, Issue:14

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

2023
Using Renin Activity to Guide Mineralocorticoid Receptor Antagonist Therapy in Patients with Low Renin and Hypertension.
    American journal of hypertension, 2023, 07-14, Volume: 36, Issue:8

    Topics: Adult; Aldosterone; Cohort Studies; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Rece

2023
Hypertension in Primary Aldosteronism Is Initiated by Salt-Induced Increases in Vascular Resistance With Reductions in Cardiac Output.
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:5

    Topics: Aldosterone; Animals; Blood Pressure; Cardiac Output; Hemodynamics; Hyperaldosteronism; Hypertension

2023
Primary Aldosteronism and Drug Resistant Hypertension: A "Chicken-Egg" Story.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2023, Volume: 131, Issue:7-08

    Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Risk Factors

2023
Evidence and Uncertainties Surrounding Renin-Guided Medical Therapy for Primary Aldosteronism.
    American journal of hypertension, 2023, 07-14, Volume: 36, Issue:8

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Miner

2023
[Adrenalectomy for primary hyperaldosteronism : retrospective review of 57 patients in CHU of Liege].
    Revue medicale de Liege, 2023, Volume: 78, Issue:4

    Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Retros

2023
Clues to suspect aldosterone breakthrough in the real world.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:7

    Topics: Aldosterone; Humans; Hypertension; Potassium; Renin

2023
Screening for primary aldosteronism in primary care.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2023, 03-20, Volume: 195, Issue:11

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Primary Health Care; Renin

2023
Unique Case of Cardiomyopathy Secondary to Adrenal Adenoma (Primary-Aldosteronism).
    The Journal of the Association of Physicians of India, 2023, Volume: 71, Issue:1

    Topics: Adenoma; Adrenocortical Adenoma; Aldosterone; Cardiomyopathies; Female; Humans; Hyperaldosteronism;

2023
Association Between Life's Simple 7 and Biomarkers of Cardiovascular Disease: Aldosterone, Interleukin-6, C-Reactive Protein.
    Journal of the American Heart Association, 2023, 05-16, Volume: 12, Issue:10

    Topics: Adolescent; Adult; Aged; Aldosterone; Biomarkers; Blood Pressure; C-Reactive Protein; Cardiovascular

2023
The Prevalence of Primary Aldosteronism in Screening Populations: Is Hypokalaemia Important?
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2023, Volume: 131, Issue:6

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Mass Screening; Prevalence

2023
Duplicated adrenal veins in primary aldosteronism misdiagnosed with ectopic aldosteronoma due to apparent bilateral aldosterone suppression.
    Blood pressure, 2023, Volume: 32, Issue:1

    Topics: Adrenal Glands; Aldosterone; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension; Hypokalemi

2023
Mineralocorticoid receptor blockade protects the kidneys but does not affect inverted blood pressure rhythm in hypertensive transgenic (mRen-2)27 rats.
    Molecular and cellular endocrinology, 2023, 07-15, Volume: 572

    Topics: Albuminuria; Aldosterone; Animals; Animals, Genetically Modified; Blood Pressure; Hypertension; Kidn

2023
Adrenocorticotropic hormone application lowered aldosterone/cortisol value on dominant side without superior surgical outcomes during adrenal venous sampling.
    Journal of clinical hypertension (Greenwich, Conn.), 2023, Volume: 25, Issue:6

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Humans; Hydrocortisone; Hyperaldosteronism

2023
Predictive performance of aldosterone-to-renin ratio in the diagnosis of primary aldosteronism in patients with resistant hypertension.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Renin; Reproducibility of Result

2023
High plasma aldosterone concentration is associated with worse 24-h ambulatory blood pressure profile in patients with primary aldosteronism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:8

    Topics: Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Car

2023
Biochemical Evaluation by Confirmatory Tests after Unilateral Adrenalectomy for Primary Aldosteronism.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2023, Volume: 2023

    Topics: Adrenalectomy; Aldosterone; Captopril; Furosemide; Humans; Hyperaldosteronism; Hypertension; Renin;

2023
Impact of gut microbiome on the renin-aldosterone system: Shika-machi Super Preventive Health Examination results.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:10

    Topics: Aldosterone; Animals; Gastrointestinal Microbiome; Humans; Hypertension; Renin; Renin-Angiotensin Sy

2023
Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production.
    Nature genetics, 2023, Volume: 55, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Cell Adhesion Molecule-1; Cytochrome

2023
Aldosterone Biosynthesis Is Potently Stimulated by Perfluoroalkyl Acids: A Link between Common Environmental Pollutants and Arterial Hypertension.
    International journal of molecular sciences, 2023, May-27, Volume: 24, Issue:11

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Alkanesulfonic Acids; Cytochrome P-450 CYP11B2; Environmental

2023
Case series: Primary aldosteronism diagnosed despite normal screening investigations: A report of three cases.
    Medicine, 2023, May-19, Volume: 102, Issue:20

    Topics: Adenoma; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Positron Emi

2023
NGAL is a Novel Target in Hypertension by Modulating the NCC-Mediated Renal Na Balance.
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:9

    Topics: Aldosterone; Animals; Hypertension; Kidney; Lipocalin-2; Mice; Mice, Knockout; Sodium; Solute Carrie

2023
Association of urinary liver-type fatty acid-binding protein with outcomes after adrenalectomy for unilateral primary aldosteronism.
    Clinica chimica acta; international journal of clinical chemistry, 2023, Aug-01, Volume: 548

    Topics: Adrenalectomy; Adult; Aldosterone; Creatinine; Female; Humans; Hyperaldosteronism; Hypertension; Liv

2023
Importance of plasma aldosterone concentrations as a clinical indicator of nocturnal hypertension in primary aldosteronism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:9

    Topics: Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hyperaldosteronism; Hype

2023
Prolonged postoperative hypoaldosteronism related to hyperkalemia in patients with aldosterone-producing adenoma.
    Endocrine journal, 2023, Sep-28, Volume: 70, Issue:9

    Topics: Adenoma; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hyperkalemi

2023
Non-suppression of renin by renal cysts in a subset of patients with primary aldosteronism-a prospective observational single center study.
    European journal of endocrinology, 2023, Jul-10, Volume: 188, Issue:7

    Topics: Adult; Aged; Aldosterone; Cysts; Female; Humans; Hyperaldosteronism; Hypertension; Kidney Diseases,

2023
Using plasma aldosterone concentrations at 1 h of saline infusion test for the diagnosis of primary aldosteronism.
    Journal of hypertension, 2023, 09-01, Volume: 41, Issue:9

    Topics: Aldosterone; Cross-Sectional Studies; Humans; Hyperaldosteronism; Hypertension; Infusions, Intraveno

2023
The Impact of Obesity on the Resolution of Hypertension Following Adrenalectomy for Primary Hyperaldosteronism.
    World journal of surgery, 2023, Volume: 47, Issue:9

    Topics: Adrenalectomy; Aldosterone; Antihypertensive Agents; Humans; Hyperaldosteronism; Hypertension; Hypok

2023
Novel mechanisms of salt-sensitive hypertension.
    Kidney international, 2023, Volume: 104, Issue:4

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Receptors

2023
Concurrent disorders of cats with diabetes mellitus and arterial systolic hypertension.
    Journal of feline medicine and surgery, 2023, Volume: 25, Issue:7

    Topics: Aldosterone; Amlodipine; Animals; Antihypertensive Agents; Cat Diseases; Cats; Diabetes Mellitus; Hy

2023
Improvement of hypertension control and left-ventricular function after cure of primary hyperparathyroidism.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Adult; Aged; Aldosterone; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hypercalcemia; Hype

2023
Could we be missing something when calculating the aldosterone-to-renin ratio?
    Journal of hypertension, 2023, 09-01, Volume: 41, Issue:9

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

2023
Reply to 'Could we be missing something when calculating the aldosterone-to-renin ratio?'
    Journal of hypertension, 2023, 09-01, Volume: 41, Issue:9

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

2023
Progress in Primary Aldosteronism 7: No better time to meet!
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2023, Volume: 131, Issue:7-08

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

2023
Aldosterone and renin concentrations and blood pressure in young Indigenous and non-Indigenous adults in the Northern Territory: a cross-sectional study.
    The Medical journal of Australia, 2023, 09-18, Volume: 219, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hyp

2023
Simple standing test without furosemide is useful in the diagnosis of primary aldosteronism.
    Scientific reports, 2023, 08-17, Volume: 13, Issue:1

    Topics: Aldosterone; Captopril; Furosemide; Humans; Hyperaldosteronism; Hypertension; Retrospective Studies

2023
Aldosterone Antagonism Is More Effective at Reducing Blood Pressure and Excessive Renal ENaC Activity in AngII-Infused Female Rats Than in Males.
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:10

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Diuretics; Female; Hypertension; Hypo

2023
Association and progression of multi-morbidity with Chronic Kidney Disease stage 3a secondary to Type 2 Diabetes Mellitus, grouped by albuminuria status in the multi-ethnic population of Northwest London: A real-world study.
    PloS one, 2023, Volume: 18, Issue:8

    Topics: Albuminuria; Aldosterone; Diabetes Mellitus, Type 2; Heart Failure; Humans; Hypertension; London; Mi

2023
Unique Gene Expression Signature in Periadrenal Adipose Tissue Identifies a High Blood Pressure Group in Patients With Cushing Syndrome.
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:11

    Topics: Adipose Tissue; Aldosterone; Angiotensins; Blood Pressure; Cushing Syndrome; Humans; Hydrocortisone;

2023
Vasoactive mediators of hypertension in obesity.
    American journal of physiology. Endocrinology and metabolism, 2023, 10-01, Volume: 325, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure; Cross-Sectional Studies; Humans

2023
Associations Between Aldosterone-Renin-Ratio and Bone Parameters Derived from Peripheral Quantitative Computed Tomography and Impact Microindentation in Men.
    Calcified tissue international, 2023, Volume: 113, Issue:5

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Male; Renin; Renin-Angiotensin System; Tomogr

2023
Aldosterone Synthase Inhibition With Lorundrostat for Uncontrolled Hypertension: The Target-HTN Randomized Clinical Trial.
    JAMA, 2023, 09-26, Volume: 330, Issue:12

    Topics: Adult; Aldosterone; Blood Pressure; Cytochrome P-450 CYP11B2; Humans; Hyperaldosteronism; Hypertensi

2023
A New Dawn for Aldosterone as a Therapeutic Target in Hypertension.
    JAMA, 2023, 09-26, Volume: 330, Issue:12

    Topics: Aldosterone; Humans; Hypertension; Molecular Targeted Therapy

2023
Primary Aldosteronism.
    American family physician, 2023, Volume: 108, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Spironolactone

2023
Surgery based on computed tomography images might be feasible for primary aldosteronism patients with visible unilateral adenoma.
    Journal of clinical hypertension (Greenwich, Conn.), 2023, Volume: 25, Issue:11

    Topics: Adenoma; Adrenal Glands; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Middl

2023
Skin NA+, K+ and water before and after surgical cure of human primary aldosteronism: Erratum.
    Journal of hypertension, 2023, 11-01, Volume: 41, Issue:11

    Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Water

2023
Who and How Should We Screen for Primary Aldosteronism?
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:12

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Reni

2023
Expression of functional mineralocorticoid receptor (MR) and G-protein coupled estrogen receptor (GPER) in human T lymphocytes.
    Steroids, 2023, Volume: 200

    Topics: Aldosterone; CD8-Positive T-Lymphocytes; GTP-Binding Proteins; Humans; Hypertension; Receptors, Estr

2023
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:12

    Topics: Aldosterone; Blood Pressure; Calcium Channels, L-Type; Diet, Sodium-Restricted; Female; Humans; Hype

2023
Central diastolic blood pressure, plasma aldosterone and uric acid are associated with microalbuminuria in essential hypertension: a case-control study.
    BMC cardiovascular disorders, 2023, 10-17, Volume: 23, Issue:1

    Topics: Albuminuria; Aldosterone; Blood Pressure; Case-Control Studies; Essential Hypertension; Humans; Hype

2023
Unilateral adrenalectomy for a drug-resistant bilateral primary aldosteronism with heart failure: pathophysiology and surgical indication.
    BMC endocrine disorders, 2023, Nov-07, Volume: 23, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Antihypertensive Agents; Bisoprolol; Eplerenone; Heart F

2023
Increasing rates of referrals for investigation of primary aldosteronism at a tertiary centre.
    The New Zealand medical journal, 2023, Nov-10, Volume: 136, Issue:1585

    Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Ant

2023
[Is there an alternative treatment option for patients with primary aldosteronism?]
    Zhonghua xin xue guan bing za zhi, 2023, Nov-24, Volume: 51, Issue:11

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

2023
Higher plasma aldosterone concentrations in patients with aortic diseases and hypertension: a retrospective observational study.
    European journal of medical research, 2023, Nov-26, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Aortic Diseases; Blood Pressure; Female; Hu

2023
Liddle syndrome presenting with normal aldosterone levels: A case report.
    Medicine, 2023, Nov-24, Volume: 102, Issue:47

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Liddle Syndrome; Renin

2023
Bilateral co-secretory lesions presenting with coexisting Cushing syndrome and primary aldosteronism: a case report.
    BMC endocrine disorders, 2023, Nov-29, Volume: 23, Issue:1

    Topics: Adrenocortical Adenoma; Adrenocorticotropic Hormone; Aldosterone; Cushing Syndrome; Female; Humans;

2023
Historical changes and between-facility differences in adrenal venous sampling for primary aldosteronism in Japan.
    Journal of human hypertension, 2020, Volume: 34, Issue:1

    Topics: Adrenal Glands; Aldosterone; Blood Specimen Collection; Endocrinology; Female; Hematologic Tests; Hu

2020
Quantitation and clinical evaluation of plasma aldosterone by ultra-performance liquid chromatography-mass spectrometry.
    Journal of chromatography. A, 2020, Jan-04, Volume: 1609

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Chromatography, High Pressure Liquid; Enzym

2020
Rare cause of severe hypertension in an adolescent boy presenting with short stature: Answers.
    Pediatric nephrology (Berlin, Germany), 2020, Volume: 35, Issue:3

    Topics: Adolescent; Aldosterone; Body Height; Cullin Proteins; Developmental Disabilities; Diagnosis, Differ

2020
A rare cause of hypertension in childhood: Questions.
    Pediatric nephrology (Berlin, Germany), 2020, Volume: 35, Issue:1

    Topics: Aldosterone; Alkalosis; Bartter Syndrome; Child; Child, Preschool; Consanguinity; Female; Humans; Hy

2020
A rare cause of hypertension in childhood: Answers.
    Pediatric nephrology (Berlin, Germany), 2020, Volume: 35, Issue:1

    Topics: Aldosterone; Alkalosis; Bartter Syndrome; Child; Child, Preschool; Consanguinity; Cortisone; Diagnos

2020
Interpreting stimulated plasma renin and aldosterone to select physiologically individualized therapy for resistant hypertension: importance of the class of stimulating drugs.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2019, Volume: 42, Issue:12

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin-Co

2019
ANO4 (Anoctamin 4) Is a Novel Marker of Zona Glomerulosa That Regulates Stimulated Aldosterone Secretion.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 74, Issue:5

    Topics: Adrenal Cortex; Aldosterone; Analysis of Variance; Anoctamins; Cell Communication; Cell Proliferatio

2019
Adherence to consensus guidelines for screening of primary aldosteronism in an urban healthcare system.
    Surgery, 2020, Volume: 167, Issue:1

    Topics: Aged; Aldosterone; Animals; Consensus; Female; Guideline Adherence; Humans; Hyperaldosteronism; Hype

2020
A Young Female With Refractory Hypertension.
    Urology, 2020, Volume: 135

    Topics: Adult; Aldosterone; Antihypertensive Agents; Drug Resistance; Drug Therapy, Combination; Female; Hum

2020
Seated saline infusion test in predicting subtype diagnosis of primary aldosteronism.
    Clinical endocrinology, 2019, Volume: 91, Issue:6

    Topics: Adrenocortical Adenoma; Adult; Aldosterone; Cosyntropin; Female; Humans; Hyperaldosteronism; Hyperte

2019
The hypertensive child.
    Australian journal of general practice, 2019, Volume: 48, Issue:12

    Topics: Abdominal Pain; Adrenocorticotropic Hormone; Aldosterone; Amlodipine; Antihypertensive Agents; Catec

2019
Simplifying the Diagnosis of Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2020, 04-01, Volume: 105, Issue:4

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium

2020
Mild primary aldosteronism (PA) followed by overt PA are possibly the most common forms of low renin hypertension: a single-center retrospective study.
    Journal of human hypertension, 2020, Volume: 34, Issue:9

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Retrospective Studies

2020
Construction of a predictive scoring system as a guide to screening and confirmation of the diagnosis of primary aldosteronism.
    Clinical endocrinology, 2020, Volume: 92, Issue:3

    Topics: Adolescent; Adult; Aged; Aldosterone; Cross-Sectional Studies; Diagnostic Techniques, Endocrine; Fem

2020
Unilateral primary aldosteronism as an independent risk factor for vertebral fracture.
    Clinical endocrinology, 2020, Volume: 92, Issue:3

    Topics: Adult; Aged; Aldosterone; Case-Control Studies; Cross-Sectional Studies; Female; Humans; Hyperaldost

2020
[Stress the standardized diagnosis and management of primary aldosteronism].
    Zhonghua nei ke za zhi, 2020, 01-01, Volume: 59, Issue:1

    Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hyperkalemia; Hypertension; Renin

2020
Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals.
    The Journal of steroid biochemistry and molecular biology, 2020, Volume: 199

    Topics: Aldosterone; Animals; Antifungal Agents; Azoles; Cricetinae; Disease Models, Animal; Drug Monitoring

2020
NATURE OF CORRELATIONS AND DEPENDENCE OF PLASMA CONCENTRATIONS OF GALECTIN-3 AND ALDOSTERONE ON DIFFERENT CLINICAL CHARACTERISTICS IN MALE AND FEMALE PATIENTS WITH ARTERIAL HYPERTENSION.
    Georgian medical news, 2019, Issue:297

    Topics: Aldosterone; Female; Galectin 3; Humans; Hypertension; Male; Middle Aged; Obesity; Risk Factors

2019
Two Mineralocorticoid Receptor-Mediated Mechanisms of Pendrin Activation in Distal Nephrons.
    Journal of the American Society of Nephrology : JASN, 2020, Volume: 31, Issue:4

    Topics: Aldosterone; Animals; Disease Models, Animal; Hypertension; Mice; Mice, Knockout; Nephrons; Receptor

2020
Pharmacodynamics and metabonomics study of Tianma Gouteng Decoction for treatment of spontaneously hypertensive rats with liver-yang hyperactivity syndrome.
    Journal of ethnopharmacology, 2020, May-10, Volume: 253

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; C-Reactive Protein; Drugs

2020
Appropriate timing for a biochemical evaluation after adrenalectomy for unilateral aldosterone-producing adenoma.
    Clinical endocrinology, 2020, Volume: 92, Issue:6

    Topics: Adenoma; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Retrospective Studies

2020
The effect of vitamin D treatment on clinical and biochemical outcomes of primary aldosteronism.
    Clinical endocrinology, 2020, Volume: 92, Issue:6

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Parathyroid Hormone; Renin; V

2020
Aldosterone-to-renin ratio and blood pressure in young adults from the general population.
    American heart journal, 2020, Volume: 222

    Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Female; Humans; Hypertension; Male; Morbidity; Popul

2020
mTORC1 Deficiency Modifies Volume Homeostatic Responses to Dietary Sodium in a Sex-Specific Manner.
    Endocrinology, 2020, 05-01, Volume: 161, Issue:5

    Topics: Aldosterone; Animals; Blood Pressure; Female; Homeostasis; Hypertension; Kidney; Male; Mechanistic T

2020
Determining the Prevalence of Primary Aldosteronism in Patients With New-Onset Type 2 Diabetes and Hypertension.
    The Journal of clinical endocrinology and metabolism, 2020, 04-01, Volume: 105, Issue:4

    Topics: Aldosterone; Biomarkers; China; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Hypera

2020
Not All Hypertension Is a Lifelong Disease: A Teachable Moment.
    JAMA internal medicine, 2020, 05-01, Volume: 180, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Antihypertensive Agent

2020
Differences in hypertension phenotypes between Africans and Europeans: role of environment.
    Journal of hypertension, 2020, Volume: 38, Issue:7

    Topics: Aldosterone; Black People; Blood Pressure; Echocardiography; Ethnicity; Europe; Female; Heart Ventri

2020
The risk factors for hepatic steatosis in patients with primary aldosteronism.
    Endocrine journal, 2020, Jun-29, Volume: 67, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Fatty Liver; Female; Humans; Hyperaldosteronism; Hypertension; I

2020
Aldosterone-induced hypertension is sex-dependent, mediated by T cells and sensitive to GPER activation.
    Cardiovascular research, 2021, 02-22, Volume: 117, Issue:3

    Topics: Aldosterone; Animals; Antihypertensive Agents; Benzodioxoles; Blood Pressure; Cyclopentanes; Disease

2021
Primary aldosteronism in young adults with acute stroke: Prevalence and clinical characteristics.
    Journal of the neurological sciences, 2020, 06-15, Volume: 413

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Middle Aged; Prevalence; Stroke;

2020
Age- and sex-specific reference ranges are needed for the aldosterone/renin ratio.
    Clinical endocrinology, 2020, Volume: 93, Issue:3

    Topics: Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Infant, Newb

2020
Impact of mineralocorticoid receptor blockade with direct renin inhibition in angiotensin II-dependent hypertensive mice.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2020, Volume: 43, Issue:10

    Topics: Aldosterone; Amides; Animals; Antihypertensive Agents; Drug Evaluation, Preclinical; Drug Therapy, C

2020
Autonomous Aldosterone Production and Left Ventricular Hypertrophy.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 75, Issue:6

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypertrophy, Left Ventricular

2020
Spironolactone mitigates, but does not reverse, the progression of renal fibrosis in a transgenic hypertensive rat.
    Physiological reports, 2020, Volume: 8, Issue:10

    Topics: Aldosterone; Animals; Blood Pressure; Disease Models, Animal; Fibrosis; Hypertension; Kidney Disease

2020
Elevated Renin and Aldosterone Levels in a Young Woman With Hypertension.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2020, Volume: 75, Issue:6

    Topics: Adult; Aldosterone; Androstenes; Antihypertensive Agents; Computed Tomography Angiography; Contracep

2020
The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study.
    Annals of internal medicine, 2020, 07-07, Volume: 173, Issue:1

    Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2020
The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study.
    Annals of internal medicine, 2020, 07-07, Volume: 173, Issue:1

    Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2020
The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study.
    Annals of internal medicine, 2020, 07-07, Volume: 173, Issue:1

    Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2020
The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study.
    Annals of internal medicine, 2020, 07-07, Volume: 173, Issue:1

    Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2020
Oestrogen receptors and T cells determine how sex affects aldosterone-induced hypertension.
    Cardiovascular research, 2021, 02-22, Volume: 117, Issue:3

    Topics: Aldosterone; Humans; Hypertension; Receptors, Estrogen; T-Lymphocytes

2021
[Diagnostic Efficiency of Different Screening Indexes for Primary Aldosteronism].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2020, Volume: 51, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Retrospective Studies

2020
[The Value of Serum Potassium and Ratio of Sodium to Potassium after Saline Infusion Test in Differential Diagnosis of Primary Hyperaldosteronism].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2020, Volume: 51, Issue:3

    Topics: Aldosterone; China; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Potassium; Re

2020
[Diagnosis and Treatment of Primary Aldosteronism in West China Hospital of Sichuan University from 2009 to 2018].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2020, Volume: 51, Issue:3

    Topics: Adrenal Gland Neoplasms; Aldosterone; China; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2020
Primary Aldosteronism: The Next Decade.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 76, Issue:2

    Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Ramipril; Renin

2020
Seizure and coma secondary to Conn's syndrome: a case report.
    Journal of medical case reports, 2020, Jul-15, Volume: 14, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Coma; Humans;

2020
Clinical outcomes of primary aldosteronism based on lateralization index and contralateral suppression index after adrenal venous sampling in real-world practice: a retrospective cohort study.
    BMC endocrine disorders, 2020, Jul-29, Volume: 20, Issue:1

    Topics: Adrenal Glands; Adult; Aged; Aged, 80 and over; Aldosterone; Blood Specimen Collection; Catheterizat

2020
Interplay Between Statins, Cav1 (Caveolin-1), and Aldosterone.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 76, Issue:3

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Caveolin 1; Cholesterol; Correlation of Data; Dyslipide

2020
Serum uromodulin is inversely associated with arterial hypertension and the vasoconstrictive prohormone CT-proET-1 in the population-based KORA F4 study.
    PloS one, 2020, Volume: 15, Issue:8

    Topics: Aged; Aldosterone; Endothelin-1; Female; Humans; Hypertension; Male; Peptide Fragments; Renin; Uromo

2020
The dangers of herbal teas: hypertension and weakness caused by liquorice-induced apparent mineralocorticoid excess.
    The Medical journal of Australia, 2020, Volume: 213, Issue:5

    Topics: Aldosterone; Alkalosis; Female; Glycyrrhiza; Humans; Hypertension; Hypokalemia; Middle Aged; Mineral

2020
The potential pathophysiological role of aldosterone and the mineralocorticoid receptor in anxiety and depression - Lessons from primary aldosteronism.
    Journal of psychiatric research, 2020, Volume: 130

    Topics: Aldosterone; Anxiety; Depression; Female; Humans; Hyperaldosteronism; Hypertension; Male; Receptors,

2020
Primary aldosteronism: Involvement of sympathetic system in the persistence of hypertension after surgery.
    Journal of clinical hypertension (Greenwich, Conn.), 2020, Volume: 22, Issue:9

    Topics: Adenoma; Adrenalectomy; Aldosterone; Denervation; Humans; Hyperaldosteronism; Hypertension; Laparosc

2020
Evaluation of Adrenal Vein Sampling Use and Outcomes in Patients With Primary Aldosteronism.
    The Journal of surgical research, 2020, Volume: 256

    Topics: Adrenal Cortex Function Tests; Adrenal Glands; Adrenalectomy; Adult; Aged; Aged, 80 and over; Aldost

2020
Association between renin-angiotensin-aldosterone system inhibitor treatment, neutrophil-lymphocyte ratio, D-Dimer and clinical severity of COVID-19 in hospitalized patients: a multicenter, observational study.
    Journal of human hypertension, 2021, Volume: 35, Issue:7

    Topics: Adult; Aged; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors

2021
Adrenal artery ablation for primary aldosteronism without apparent aldosteronoma: An efficacy and safety, proof-of-principle trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2020, Volume: 22, Issue:9

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Arteries; Humans; Hyperaldosteronism; Hypertension; Pros

2020
Adrenal artery ablation for primary aldosteronism without apparent aldosteronoma: An efficacy and safety, proof-of-principle trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2020, Volume: 22, Issue:9

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Arteries; Humans; Hyperaldosteronism; Hypertension; Pros

2020
Adrenal artery ablation for primary aldosteronism without apparent aldosteronoma: An efficacy and safety, proof-of-principle trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2020, Volume: 22, Issue:9

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Arteries; Humans; Hyperaldosteronism; Hypertension; Pros

2020
Adrenal artery ablation for primary aldosteronism without apparent aldosteronoma: An efficacy and safety, proof-of-principle trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2020, Volume: 22, Issue:9

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Arteries; Humans; Hyperaldosteronism; Hypertension; Pros

2020
Taiwan mini-frontier of primary aldosteronism: Updating detection and diagnosis.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2021, Volume: 120, Issue:1 Pt 1

    Topics: Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Taiwan

2021
The cytochrome 11B2 aldosterone synthase gene rs1799998 single nucleotide polymorphism determines elevated aldosterone, higher blood pressure, and reduced glomerular filtration, especially in diabetic female patients.
    Endocrine regulations, 2020, Jul-01, Volume: 54, Issue:3

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Case-Control Studies; Cytochrome P-450 CYP11B2; Diabetes M

2020
Genetics, prevalence, screening and confirmation of primary aldosteronism: a position statement and consensus of the Working Group on Endocrine Hypertension of The European Society of Hypertension.
    Journal of hypertension, 2020, Volume: 38, Issue:10

    Topics: Aldosterone; Consensus; Humans; Hyperaldosteronism; Hypertension; Prevalence

2020
Potassium losing, aldosterone producing adrenocortical carcinoma: a rare presentation.
    BMJ case reports, 2020, Sep-09, Volume: 13, Issue:9

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adult; Aldosteron

2020
Association of -344C/T polymorphism in the aldosterone synthase (CYP11B2) gene with cardiac and cerebrovascular events in Chinese patients with hypertension.
    The Journal of international medical research, 2020, Volume: 48, Issue:9

    Topics: Adult; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Card

2020
Primary Aldosteronism: New Insights Into its Detection and Cardiac Involvement.
    JACC. Cardiovascular imaging, 2020, Volume: 13, Issue:10

    Topics: Aldosterone; Extracellular Matrix; Humans; Hyperaldosteronism; Hypertension; Magnetic Resonance Spec

2020
Serum ACE2, Angiotensin II, and Aldosterone Levels Are Unchanged in Patients With COVID-19.
    American journal of hypertension, 2021, 04-02, Volume: 34, Issue:3

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibito

2021
Clinical characteristics of primary aldosteronism in newly diagnosed diabetes mellitus with hypertensive patients.
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2020, Aug-28, Volume: 45, Issue:8

    Topics: Aldosterone; Diabetes Mellitus; Humans; Hyperaldosteronism; Hypertension; Renin

2020
CASZ1b is a novel transcriptional corepressor of mineralocorticoid receptor.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2021, Volume: 44, Issue:4

    Topics: Aldosterone; Co-Repressor Proteins; DNA-Binding Proteins; Humans; Hypertension; Receptors, Mineraloc

2021
Significance of Discordant Results Between Confirmatory Tests in Diagnosis of Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2021, 01-23, Volume: 106, Issue:2

    Topics: Adrenal Glands; Aged; Aldosterone; Blood Specimen Collection; Cross-Sectional Studies; Diagnosis, Di

2021
Variability of Aldosterone Measurements During Adrenal Venous Sampling for Primary Aldosteronism.
    American journal of hypertension, 2021, 02-18, Volume: 34, Issue:1

    Topics: Adrenal Glands; Aldosterone; Blood; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension

2021
Association between renin-angiotensin-aldosterone system inhibitor use and COVID-19 hospitalization and death: a 1.4 million patient nationwide registry analysis.
    European journal of heart failure, 2021, Volume: 23, Issue:3

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; COVID-19; H

2021
Effect of sodium-glucose cotransporter-2 inhibitors on aldosterone-to-renin ratio in diabetic patients with hypertension: a retrospective observational study.
    BMC endocrine disorders, 2020, Nov-30, Volume: 20, Issue:1

    Topics: Aged; Aldosterone; Diabetes Mellitus, Type 2; Female; Humans; Hyperaldosteronism; Hypertension; Male

2020
Intraindividual Variability of Aldosterone Concentrations in Primary Aldosteronism: Implications for Case Detection.
    Hypertension (Dallas, Tex. : 1979), 2021, 03-03, Volume: 77, Issue:3

    Topics: Adult; Aldosterone; Biological Variation, Individual; Chromatography, Liquid; Female; Humans; Hypera

2021
Paradoxical Increase of 24-Hour Urinary Aldosterone Levels in Obese Patients With Resistant Hypertension on a High Salt Diet.
    American journal of hypertension, 2021, 06-22, Volume: 34, Issue:6

    Topics: Aldosterone; Cross-Sectional Studies; Humans; Hypertension; Obesity; Sodium Chloride, Dietary

2021
Repeat Adrenal Vein Sampling in Aldosteronism: Reproducibility and Interpretation of Persistently Discordant Results.
    The Journal of clinical endocrinology and metabolism, 2021, 03-08, Volume: 106, Issue:3

    Topics: Adrenal Glands; Adult; Aged; Aged, 80 and over; Aldosterone; Blood Specimen Collection; Catheterizat

2021
[Dynamic changes of renin-angiotensin-aldosterone system parameters after surgery of primary hyperparathyroidism].
    Terapevticheskii arkhiv, 2020, Nov-24, Volume: 92, Issue:10

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Calcium; Humans; Hyperparathyroidism, Primary

2020
[Primary aldosteronism: The Mayo Clinic approach].
    Terapevticheskii arkhiv, 2020, Nov-24, Volume: 92, Issue:10

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocortic

2020
High prevalence and a long delay in the diagnosis of primary aldosteronism among patients with young-onset hypertension.
    Clinical endocrinology, 2021, Volume: 94, Issue:6

    Topics: Adult; Aldosterone; Cross-Sectional Studies; Humans; Hyperaldosteronism; Hypertension; Middle Aged;

2021
Salt Intake, Aldosterone Secretion, and Obesity: Role in the Pathogenesis of Resistant Hypertension.
    American journal of hypertension, 2021, 06-22, Volume: 34, Issue:6

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Obesity; Sodium Chloride, Dietary

2021
Primary aldosteronism: considerations about the evaluation of the aldosterone to renin ratio during canrenone treatment.
    Journal of endocrinological investigation, 2021, Volume: 44, Issue:9

    Topics: Aldosterone; Antihypertensive Agents; Canrenone; Diagnostic Techniques, Endocrine; Duration of Thera

2021
Exploration Of The Seated Saline Suppression Test For The Diagnosis Of Primary Aldosteronism In The Chinese Population.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2020, Volume: 26, Issue:8

    Topics: Adrenocortical Adenoma; Aldosterone; Asian People; Humans; Hyperaldosteronism; Hypertension; Renin

2020
Mineralocorticoid Receptor Antagonists Decrease the Rates of Positive Screening for Primary Aldosteronism.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2020, Volume: 26, Issue:12

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Humans; Hyp

2020
Aldosterone, gut microbiome and hypertension: selected papers from APCH 2019.
    Journal of human hypertension, 2021, Volume: 35, Issue:2

    Topics: Aldosterone; Gastrointestinal Microbiome; Humans; Hypertension

2021
Primary Aldosteronism: Strike Two.
    American journal of hypertension, 2021, 02-18, Volume: 34, Issue:1

    Topics: Aldosterone; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hypertension

2021
Growth differentiation factor 15 levels are similar in primary aldosteronism and essential hypertension and do not predict arterial inflammation.
    Journal of hypertension, 2021, 03-01, Volume: 39, Issue:3

    Topics: Aldosterone; Arteritis; Essential Hypertension; Growth Differentiation Factor 15; Humans; Hyperaldos

2021
Outcomes of Adrenalectomy and the Aldosteronoma Resolution Score in the Black and Hispanic Population.
    World journal of surgery, 2021, Volume: 45, Issue:5

    Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Black or African American; Female; Hispanic or L

2021
Automated Mindray CL-1200i chemiluminescent assays of renin and aldosterone for the diagnosis of primary aldosteronism.
    Clinical chemistry and laboratory medicine, 2021, 04-27, Volume: 59, Issue:5

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Luminescent Measurements; Renin

2021
Novel chemiluminescent immunoassay to measure plasma aldosterone and plasma active renin concentrations for the diagnosis of primary aldosteronism.
    Journal of human hypertension, 2022, Volume: 36, Issue:1

    Topics: Aldosterone; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension; Radioimmunoassay; Ren

2022
Primary aldosteronism investigation in the elderly: challenges and opportunities.
    Internal medicine journal, 2021, Volume: 51, Issue:1

    Topics: Aged; Aldosterone; Humans; Hyperaldosteronism; Hypertension

2021
A Flounder Fish Peptide Shows Anti-Hypertensive Effects by Suppressing the Renin-Angiotensin-Aldosterone System and Endothelin-1.
    Protein and peptide letters, 2021, Volume: 28, Issue:7

    Topics: Administration, Oral; Aldosterone; Amino Acid Sequence; AMP-Activated Protein Kinases; Angiotensin I

2021
Treatment of Primary Aldosteronism Increases Plasma Epoxyeicosatrienoic Acids.
    Hypertension (Dallas, Tex. : 1979), 2021, Volume: 77, Issue:4

    Topics: Adrenalectomy; Adult; Aldosterone; Animals; Arachidonic Acids; Blood Pressure; Epoxide Hydrolases; F

2021
Association of Serum Aldosterone and Plasma Renin Activity With Ambulatory Blood Pressure in African Americans: The Jackson Heart Study.
    Circulation, 2021, 06-15, Volume: 143, Issue:24

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Black or African American; Blood Pressure; Female; Huma

2021
Altered Taste Perception for Sodium Chloride in Patients With Primary Aldosteronism: A Prospective Cohort Study.
    Hypertension (Dallas, Tex. : 1979), 2021, Volume: 77, Issue:4

    Topics: Adrenalectomy; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Min

2021
Volumetric evaluation of CT images of adrenal glands in primary aldosteronism.
    Journal of endocrinological investigation, 2021, Volume: 44, Issue:11

    Topics: Adrenal Glands; Aldosterone; Antihypertensive Agents; Cone-Beam Computed Tomography; Correlation of

2021
Evaluation of Hypokalemia.
    JAMA, 2021, 03-23, Volume: 325, Issue:12

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Algorithms; Female; Humans; Hyperaldosteronism; Hyper

2021
Seated Saline Suppression Test Is Comparable With Captopril Challenge Test for the Diagnosis of Primary Aldosteronism: A Prospective Study.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2021, Volume: 27, Issue:4

    Topics: Aldosterone; Captopril; Humans; Hyperaldosteronism; Hypertension; Prospective Studies; Renin

2021
[Primary aldosteronism: from diagnosis to therapy in clinical practice].
    Giornale italiano di cardiologia (2006), 2021, Volume: 22, Issue:4

    Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Ant

2021
Aldosterone-producing adenoma associated with non-suppressed renin: a case series.
    Journal of human hypertension, 2022, Volume: 36, Issue:4

    Topics: Adenoma; Adrenocortical Adenoma; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male

2022
Primary Aldosteronism with Parathyroid Hormone Elevation: A Single-center Retrospective Study.
    Internal medicine (Tokyo, Japan), 2021, Volume: 60, Issue:7

    Topics: Aldosterone; Calcium; Humans; Hyperaldosteronism; Hypertension; Parathyroid Hormone; Retrospective S

2021
Association of aldosterone and blood pressure with the risk for cardiovascular events after treatments in primary aldosteronism.
    Atherosclerosis, 2021, Volume: 324

    Topics: Aldosterone; Blood Pressure; Cardiovascular Diseases; Female; Humans; Hyperaldosteronism; Hypertensi

2021
Hypokalemia-Induced Rhabdomyolysis Caused by Adrenal Tumor-Related Primary Aldosteronism: A Report of 2 Cases.
    The American journal of case reports, 2021, Apr-10, Volume: 22

    Topics: Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; M

2021
Prevalence, Subtype Classification, and Outcomes of Treatment of Primary Aldosteronism: A Prospective Study in China.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2021, Volume: 27, Issue:5

    Topics: Aldosterone; China; Humans; Hyperaldosteronism; Hypertension; Prevalence; Prospective Studies; Renin

2021
MicroRNA 21 and microRNA 155 levels in resistant hypertension, and their relationships with aldosterone.
    Renal failure, 2021, Volume: 43, Issue:1

    Topics: Adult; Aged; Aldosterone; Blood Pressure Monitoring, Ambulatory; Case-Control Studies; Female; Human

2021
[HYPERTENSION IN A YOUNG WOMAN WITH ANXIETY DISORDER: THE CHICKEN OR THE EGG?]
    Harefuah, 2021, Volume: 160, Issue:4

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Anxiety Disorder

2021
Mineralocorticoid Receptor Antagonist Effect on Aldosterone to Renin Ratio in Patients With Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2021, 08-18, Volume: 106, Issue:9

    Topics: Adolescent; Adrenalectomy; Adult; Aged; Aldosterone; Canrenone; Cohort Studies; False Negative React

2021
The Effects of Short-Term Changes in Sodium Intake on Plasma Marinobufagenin Levels in Patients with Primary Salt-Sensitive and Salt-Insensitive Hypertension.
    Nutrients, 2021, Apr-29, Volume: 13, Issue:5

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Bufanolides; Female; Humans; Hypertension; Male; Midd

2021
Hemodynamic and Non-Hemodynamic Components of Cardiac Remodeling in Primary Aldosteronism.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Blood Pressure; Echocardiography; Essenti

2021
Aldosterone Secretion in Patients With Primary Hyperparathyroidism Without Arterial Hypertension.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2021, Volume: 27, Issue:11

    Topics: Aldosterone; Humans; Hyperparathyroidism, Primary; Hypertension; Renin-Angiotensin System; Retrospec

2021
Allisartan isoproxil reduces mortality of stroke-prone rats and protects against cerebrovascular, cardiac, and aortic damage.
    Acta pharmacologica Sinica, 2021, Volume: 42, Issue:6

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Aorti

2021
Urinary sodium/potassium ratio as a screening tool for hyperaldosteronism in men with hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2021, Volume: 44, Issue:9

    Topics: Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potas

2021
Aldosterone contributes to hypertension in male mice inducibly overexpressing human endothelin-1 in endothelium.
    Journal of hypertension, 2021, 09-01, Volume: 39, Issue:9

    Topics: Aldosterone; Animals; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Humans; Hypertension;

2021
Determination of adrenal hypersecretion in primary Aldosteronism without aldosterone-production adenomas.
    BMC endocrine disorders, 2021, May-31, Volume: 21, Issue:1

    Topics: Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Diagnosis, Differential; Female; Follow-Up Stud

2021
Comparison of cystatin C-based and creatinine-based glomerular filtration rate in the prediction of postoperative residual hypertension in aldosterone-producing adenoma patients after adrenalectomy.
    Clinica chimica acta; international journal of clinical chemistry, 2021, Volume: 520

    Topics: Adenoma; Adrenalectomy; Aldosterone; Biomarkers; Creatinine; Cystatin C; Glomerular Filtration Rate;

2021
Characterization of the Renin-Angiotensin-Aldosterone System in Young Healthy Black Adults: The African Prospective Study on the Early Detection and Identification of Hypertension and Cardiovascular Disease (African-PREDICT Study).
    Hypertension (Dallas, Tex. : 1979), 2021, Volume: 78, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Black People; Blood Pressure; Cardiovascular Diseases; Early Dia

2021
Letter to the Editor from Rui Zhu et al: "Performance of the Aldosterone-to-Renin Ratio as a Screening Test for Primary Aldosteronism: A Systematic Review and Meta-Analysis".
    The Journal of clinical endocrinology and metabolism, 2021, 09-27, Volume: 106, Issue:10

    Topics: Aldosterone; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hypertension; Renin

2021
Response Letter to the Editor from Zhu et al: "Performance of the Aldosterone-to-Renin Ratio as a Screening Test for Primary Aldosteronism: A Systematic Review and Meta-Analysis".
    The Journal of clinical endocrinology and metabolism, 2021, 09-27, Volume: 106, Issue:10

    Topics: Aldosterone; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hypertension; Renin

2021
Subtype-specific trends in the clinical picture of primary aldosteronism over a 13-year period.
    Journal of hypertension, 2021, 11-01, Volume: 39, Issue:11

    Topics: Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Retro

2021
Aldosterone hyperreactivity to acute psychosocial stress induction in men with essential hypertension.
    Hormones and behavior, 2021, Volume: 134

    Topics: Aldosterone; Blood Pressure; Essential Hypertension; Humans; Hypertension; Male; Stress, Psychologic

2021
Does the Aldosterone: Renin Ratio Predict Future Blood Pressure in Young Adults?
    Hypertension (Dallas, Tex. : 1979), 2021, Volume: 78, Issue:2

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Renin; Renin-Angiotensin System; Young Adult

2021
Associastion of In-hospital Use of Statins, Aspirin, and Renin-Angiotensin-Aldosterone Inhibitors with Mortality and ICU Admission Due to COVID-19.
    Advances in experimental medicine and biology, 2021, Volume: 1327

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensin

2021
Prevalence of Primary Aldosteronism Across the Stages of Hypertension Based on a New Combined Overnight Test.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2021, Volume: 53, Issue:7

    Topics: Adult; Aged; Aldosterone; Biomarkers; Case-Control Studies; Diagnostic Tests, Routine; Female; Follo

2021
A case of primary aldosteronism with a negative aldosterone-to-renin ratio.
    BMC cardiovascular disorders, 2021, 07-22, Volume: 21, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Biomarkers; B

2021
Lipid Profiles in Primary Aldosteronism Compared with Essential Hypertension: Propensity-Score Matching Study.
    Endocrinology and metabolism (Seoul, Korea), 2021, Volume: 36, Issue:4

    Topics: Aldosterone; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension; Lipids; Retrospective

2021
Aldosterone and Primary Aldosteronism: Star Performers in Hypertension Research.
    Hypertension (Dallas, Tex. : 1979), 2021, Volume: 78, Issue:3

    Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension

2021
Updates on Renin-Angiotensin System Blockers in Hypertensive Patients With COVID-19.
    American journal of hypertension, 2021, 11-20, Volume: 34, Issue:11

    Topics: Aldosterone; Angiotensins; Antihypertensive Agents; COVID-19; Humans; Hypertension; Renin; Renin-Ang

2021
Monogenic forms of low-renin hypertension: clinical and molecular insights.
    Pediatric nephrology (Berlin, Germany), 2022, Volume: 37, Issue:7

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin

2022
Renin Phenotypes Characterize Vascular Disease, Autonomous Aldosteronism, and Mineralocorticoid Receptor Activity.
    The Journal of clinical endocrinology and metabolism, 2017, 06-01, Volume: 102, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension; Linear Models;

2017
Association of aldosterone excess and apnea-hypopnea index in patients with resistant hypertension.
    Scientific reports, 2017, 03-22, Volume: 7

    Topics: Aged; Aldosterone; Coronary Vasospasm; Female; Humans; Hypertension; Male; Middle Aged; Sleep Apnea

2017
Aldosterone a Relevant Factor in the Beginning and Evolution of Arterial Hypertension.
    American journal of hypertension, 2017, 05-01, Volume: 30, Issue:5

    Topics: Aldosterone; Essential Hypertension; Humans; Hypertension; Renin

2017
Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice.
    Scientific reports, 2017, 03-28, Volume: 7, Issue:1

    Topics: Aldosterone; Animals; Biomarkers; Blood Pressure; Cytochrome P-450 CYP11B2; Electrolytes; Fadrozole;

2017
Role and Regulation of MicroRNAs in Aldosterone-Mediated Cardiac Injury and Dysfunction in Male Rats.
    Endocrinology, 2017, 06-01, Volume: 158, Issue:6

    Topics: Aldosterone; Animals; Gene Expression Regulation; Heart; Heart Diseases; Hyperaldosteronism; Hyperte

2017
Urine exosomes from healthy and hypertensive pregnancies display elevated level of α-subunit and cleaved α- and γ-subunits of the epithelial sodium channel-ENaC.
    Pflugers Archiv : European journal of physiology, 2017, Volume: 469, Issue:9

    Topics: Adult; Aldosterone; Epithelial Sodium Channels; Exosomes; Female; Fibrinolysin; Humans; Hypertension

2017
Physiological and Pathological Roles in Human Adrenal of the Glomeruli-Defining Matrix Protein NPNT (Nephronectin).
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 69, Issue:6

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Cytochrome P-450 CYP11B2; Extracellular Matri

2017
Relationship and associated mechanisms between ambulatory blood pressure and clinic blood pressure with prevalent cardiovascular disease in diabetic hypertensive patients.
    Medicine, 2017, Volume: 96, Issue:16

    Topics: Aged; Aldosterone; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Body Mass In

2017
Hypertensive Patients That Respond to Aldosterone Antagonists May Have a Nonclassical 11β-HSD2 Deficiency.
    American journal of hypertension, 2017, 08-01, Volume: 30, Issue:8

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Humans; Hypertension; Mineralocorticoid Re

2017
Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: The aldosterone-mineralocorticoid receptor-Nox1 axis.
    Life sciences, 2017, Jun-15, Volume: 179

    Topics: Acetylcholine; Aldosterone; Animals; Aorta; Blood Pressure; Galectin 3; Hypertension; Male; Mesenter

2017
Aldosterone and Mineralocorticoid Receptors-Physiology and Pathophysiology.
    International journal of molecular sciences, 2017, May-11, Volume: 18, Issue:5

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenocorticotropic Hormone; Aldosterone; Animals; Arteries;

2017
A case of confirmed primary hyperaldosteronism diagnosed despite normal screening investigations.
    The New Zealand medical journal, 2017, May-12, Volume: 130, Issue:1455

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertens

2017
Quantitative Value of Aldosterone-Renin Ratio for Detection of Aldosterone-Producing Adenoma: The Aldosterone-Renin Ratio for Primary Aldosteronism (AQUARR) Study.
    Journal of the American Heart Association, 2017, May-21, Volume: 6, Issue:5

    Topics: Adrenocortical Adenoma; Aldosterone; Biomarkers, Tumor; Blood Pressure; Disease Progression; Female;

2017
Rating the blood pressure outcome after adrenalectomy for unilateral primary aldosteronism.
    The lancet. Diabetes & endocrinology, 2017, Volume: 5, Issue:9

    Topics: Adrenalectomy; Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Retrospective

2017
NEFM (Neurofilament Medium) Polypeptide, a Marker for Zona Glomerulosa Cells in Human Adrenal, Inhibits D1R (Dopamine D1 Receptor)-Mediated Secretion of Aldosterone.
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 70, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cell Line, Tumor; Cell Proliferation; Dopamine Agonis

2017
Of Mice and Man and the Regulation of Aldosterone Secretion.
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 70, Issue:2

    Topics: Aldosterone; Biological Transport; Cell Communication; Humans; Hypertension

2017
Rapid Diagnosis of Primary Aldosteronism: Oxymoron or One Small Step?
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 70, Issue:2

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

2017
Rapid Screening of Primary Aldosteronism by a Novel Chemiluminescent Immunoassay.
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 70, Issue:2

    Topics: Adult; Aldosterone; Antihypertensive Agents; Chromatography, Liquid; Comparative Effectiveness Resea

2017
Characteristics of hypertension in premature infants with and without chronic lung disease: a long-term multi-center study.
    Pediatric nephrology (Berlin, Germany), 2017, Volume: 32, Issue:11

    Topics: Aldosterone; Antihypertensive Agents; Chronic Disease; Female; Humans; Hypertension; Infant; Infant,

2017
Bypass of confirmatory tests for case detection of primary aldosteronism in leaner patients?
    Journal of clinical hypertension (Greenwich, Conn.), 2017, Volume: 19, Issue:8

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Obesity; Thinness

2017
Prevalence of primary aldosteronism without hypertension in the general population: Results in Shika study.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2018, Volume: 40, Issue:2

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Disease Progression; Female; Humans; Hyperaldosteronism; H

2018
Prenatal exposure to angiotensin II increases blood pressure and decreases salt sensitivity in rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2017, Volume: 39, Issue:6

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Female; Heart Ventricles; Hypertension; Kidney

2017
Associations between glycaemic control and activation of the renin-angiotensin-aldosterone system in participants with type 2 diabetes mellitus and hypertension.
    Annals of clinical biochemistry, 2018, Volume: 55, Issue:3

    Topics: Aged; Aldosterone; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glycat

2018
Mineralocorticoids: the secret of muscle reflex dysfunction in hypertension?
    American journal of physiology. Heart and circulatory physiology, 2017, 11-01, Volume: 313, Issue:5

    Topics: Aldosterone; Animals; Hypertension; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Rats

2017
Cerebrovascular recovery after stroke with individual and combined losartan and captopril treatment of SHRsp.
    Vascular pharmacology, 2017, Volume: 96-98

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim

2017
Screening of primary aldosteronism by clinical features and daily laboratory tests: combination of urine pH, sex, and serum K.
    Journal of hypertension, 2018, Volume: 36, Issue:2

    Topics: Adult; Aldosterone; Area Under Curve; Biomarkers; Female; Humans; Hydrogen-Ion Concentration; Hypera

2018
Microalbuminuria and plasma aldosterone levels in nondiabetic treatment-naïve patients with hypertension.
    Journal of hypertension, 2017, Volume: 35, Issue:12

    Topics: Adult; Aged; Albuminuria; Aldosterone; Female; Humans; Hypertension; Hypertension, Renal; Kidney; Ki

2017
Nocturnal diastolic blood pressure decline is associated with higher 25-hydroxyvitamin D level and standing plasma renin activity in a hypertensive population.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2017, Volume: 39, Issue:8

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Blood Pressure; Blood Pres

2017
Disruption of the with no lysine kinase-STE20-proline alanine-rich kinase pathway reduces the hypertension induced by angiotensin II.
    Journal of hypertension, 2018, Volume: 36, Issue:2

    Topics: Aldosterone; Amiloride; Angiotensin II; Animals; Blood Pressure; Diuretics; Epithelial Sodium Channe

2018
Aldosterone induces left ventricular subclinical systolic dysfunction: a strain imaging study.
    Journal of hypertension, 2018, Volume: 36, Issue:2

    Topics: Adult; Aged; Aldosterone; Echocardiography; Essential Hypertension; Female; Heart; Humans; Hyperaldo

2018
Favorable surgical outcomes of aldosterone-producing adenoma based on lateralization by CT imaging and hypokalemia: a non-AVS-based strategy.
    International urology and nephrology, 2017, Volume: 49, Issue:12

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi

2017
Aldosterone to Renin Ratio as a Screening Instrument for Primary Aldosteronism in a Middle-Aged Population with Atrial Fibrillation.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2017, Volume: 49, Issue:11

    Topics: Aldosterone; Atrial Fibrillation; Female; Humans; Hyperaldosteronism; Hypertension; Male; Mass Scree

2017
Changes in plasma aldosterone and electrolytes levels, kidney epithelial sodium channel (ENaC) and blood pressure in normotensive WKY and hypertensive SHR rats following gonadectomy and chronic testosterone treatment.
    Steroids, 2017, Volume: 128

    Topics: Aldosterone; Animals; Blood Pressure; Castration; Disease Models, Animal; Electrolytes; Epithelial S

2017
PECULIARITIES OF REMODELING OF HEART AND NEUROHUMORAL STATUS IN PATIENTS WITH CHRONIC HEART FAILURE AND CONCOMITANT RENAL DISEASE DEPENDING ON THE VALUE OF THE EJECTION FRACTION OF THE LEFT VENTRICLE.
    Georgian medical news, 2017, Issue:270

    Topics: Aldosterone; Chronic Disease; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Myocar

2017
KCNJ5 mutation as a predictor for resolution of hypertension after surgical treatment of aldosterone-producing adenoma.
    Journal of hypertension, 2018, Volume: 36, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Female; G Prote

2018
The Spectrum of Subclinical Primary Aldosteronism and Incident Hypertension: A Cohort Study.
    Annals of internal medicine, 2017, Nov-07, Volume: 167, Issue:9

    Topics: Aged; Aged, 80 and over; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; H

2017
Aldosterone-to-renin ratio depends on age and sex in children attending a clinic for cardiovascular risk assessment.
    Journal of hypertension, 2018, Volume: 36, Issue:2

    Topics: Adolescent; Age Factors; Aldosterone; Blood Pressure; Body Weight; Cardiovascular Diseases; Child; C

2018
Urinary Cadmium Excretion Is Associated With Increased Synthesis of Cortico- and Sex Steroids in a Population Study.
    The Journal of clinical endocrinology and metabolism, 2018, 02-01, Volume: 103, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Aged; Aldosterone; Cadmium; Cohort Studies; Family; Female; Gonadal

2018
Primary Hyperaldosteronism Due to Adrenocortical Adenoma: a Case Report.
    Acta medica Indonesiana, 2017, Volume: 49, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Female; Humans;

2017
Central and peripheral slow-pressor mechanisms contributing to Angiotensin II-salt hypertension in rats.
    Cardiovascular research, 2018, 02-01, Volume: 114, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Arterial Pressure; Brain; Cardenolides; Cardiovascular System;

2018
Primary aldosteronism and cardiovascular risk, before and after treatment.
    The lancet. Diabetes & endocrinology, 2018, Volume: 6, Issue:1

    Topics: Aldosterone; Cardiovascular Diseases; Humans; Hyperaldosteronism; Hypertension; Risk Factors

2018
Refining the Definitions of Biochemical and Clinical Cure for Primary Aldosteronism Using the Primary Aldosteronism Surgical Outcome (PASO) Classification System.
    World journal of surgery, 2018, Volume: 42, Issue:2

    Topics: Adrenalectomy; Adult; Aged; Aldosterone; Biomarkers; Female; Humans; Hyperaldosteronism; Hypertensio

2018
It's Complicated: How Often are Patients with Primary Aldosteronism Cured After Adrenalectomy?
    World journal of surgery, 2018, Volume: 42, Issue:2

    Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

2018
Mineralocorticoid receptor antagonism protects the aorta from vascular smooth muscle cell proliferation and collagen deposition in a rat model of adrenal aldosterone-producing adenoma.
    Journal of physiology and biochemistry, 2018, Volume: 74, Issue:1

    Topics: ACTH-Secreting Pituitary Adenoma; Aldosterone; Animals; Antihypertensive Agents; Aorta; Cell Prolife

2018
Misdiagnosis of a hidden cause of hypertension: a case report.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2017, Volume: 67, Issue:665

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Diagnostic Errors; Female; Huma

2017
Adrenal Vein Sampling Is the Preferred Method to Select Patients With Primary Aldosteronism for Adrenalectomy: Pro Side of the Argument.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Austra

2018
Renin Activity and Aldosterone Assay Among Nigerians with Hypertension and Normotension: An Insight into Normative Values and Clinical Correlates.
    Current hypertension reviews, 2018, Volume: 14, Issue:1

    Topics: Adult; Aldosterone; Biomarkers; Black People; Blood Pressure; Case-Control Studies; Cross-Sectional

2018
Aldosterone as a mediator of microvascular and macrovascular damage in a population of normotensive to early-stage hypertensive individuals.
    Journal of the American Society of Hypertension : JASH, 2018, Volume: 12, Issue:1

    Topics: Adult; Albuminuria; Aldosterone; Blood Pressure; Correlation of Data; Female; Humans; Hypertension;

2018
Double hit! A unique case of resistant hypertension.
    BMJ case reports, 2017, Dec-22, Volume: 2017

    Topics: Adrenal Glands; Aldosterone; Diuretics; Female; Humans; Hyperaldosteronism; Hyperparathyroidism, Pri

2017
Mutations of the Twik-Related Acid-Sensitive K+ Channel 2 Promoter in Human Primary Aldosteronism.
    Endocrinology, 2018, 03-01, Volume: 159, Issue:3

    Topics: Adrenocortical Adenoma; Adult; Aldosterone; Binding Sites; Female; Germ-Line Mutation; Humans; Hyper

2018
Prevalence of primary aldosteronism in primary care: a cross-sectional study.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2018, Volume: 68, Issue:667

    Topics: Adult; Aged; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension;

2018
RAGE-aptamer attenuates deoxycorticosterone acetate/salt-induced renal injury in mice.
    Scientific reports, 2018, 02-08, Volume: 8, Issue:1

    Topics: Acetates; Acute Kidney Injury; Aldosterone; Animals; Aptamers, Peptide; Blood Pressure; Desoxycortic

2018
Can aldosterone break your heart? Takotsubo cardiomyopathy in a patient with newly diagnosed primary aldosteronism.
    BMJ case reports, 2018, Feb-05, Volume: 2018

    Topics: Aldosterone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agen

2018
Case detection in primary aldosteronism: high-diagnostic value of the aldosterone-to-renin ratio when performed under standardized conditions.
    Journal of hypertension, 2018, Volume: 36, Issue:7

    Topics: Adult; Aged; Aldosterone; False Negative Reactions; False Positive Reactions; Female; Humans; Hypera

2018
Uterine fibroids and risk of hypertension: Implication of inflammation and a possible role of the renin-angiotensin-aldosterone system.
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:4

    Topics: Aldosterone; Cardiovascular Diseases; Female; Humans; Hypertension; Inflammation; Leiomyoma; Renin;

2018
Plasma renin activity to plasma aldosterone concentration ratio for the assessment of essential hypertensive patients in real-life clinical practice.
    Journal of hypertension, 2018, Volume: 36, Issue:2

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Humans; Hypertension; Renin;

2018
Primary aldosteronism: key characteristics at diagnosis: a trend toward milder forms.
    European journal of endocrinology, 2018, Volume: 178, Issue:6

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Female; Germany; Humans; Hyperaldostero

2018
Fluid retention, aldosterone excess, and treatment of resistant hypertension.
    The lancet. Diabetes & endocrinology, 2018, Volume: 6, Issue:6

    Topics: Aldosterone; Amiloride; Blood Pressure; Hemodynamics; Humans; Hypertension; Spironolactone

2018
Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies.
    The lancet. Diabetes & endocrinology, 2018, Volume: 6, Issue:6

    Topics: Aldosterone; Amiloride; Antihypertensive Agents; Bisoprolol; Blood Pressure; Doxazosin; Female; Hemo

2018
Licorice-induced apparent mineralocorticoid excess compounded by excessive use of terbutaline and high water intake.
    BMJ case reports, 2018, Apr-19, Volume: 2018

    Topics: Aldosterone; Asthma; Bronchodilator Agents; Diagnosis, Differential; Glycyrrhiza; Humans; Hypertensi

2018
Olmesartan combined with renal denervation reduces blood pressure in association with sympatho-inhibitory and aldosterone-reducing effects in hypertensive mice with chronic kidney disease.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2019, Volume: 41, Issue:3

    Topics: Albuminuria; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Combined Mo

2019
Relationship between sodium, pentraxin-3 and aldosterone in inflammation and cardiovascular risk.
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:5

    Topics: Aldosterone; C-Reactive Protein; Cardiovascular Diseases; Humans; Hypertension; Inflammation; Potass

2018
Primary aldosteronism in patients with adrenal incidentaloma: Is screening appropriate for everyone?
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:5

    Topics: Adrenal Gland Neoplasms; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypoka

2018
Is the plasma aldosterone-to-renin ratio associated with blood pressure response to treatment in general practice?
    Family practice, 2019, 03-20, Volume: 36, Issue:2

    Topics: Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pressure; Female; General Practice; Humans;

2019
Role of Cryptochrome-1 and Cryptochrome-2 in Aldosterone-Producing Adenomas and Adrenocortical Cells.
    International journal of molecular sciences, 2018, Jun-05, Volume: 19, Issue:6

    Topics: Adenoma; Aldosterone; Angiotensin II; Animals; Cell Line, Tumor; Cryptochromes; Gene Expression Regu

2018
Intestinal Mineralocorticoid Receptor Contributes to Epithelial Sodium Channel-Mediated Intestinal Sodium Absorption and Blood Pressure Regulation.
    Journal of the American Heart Association, 2018, 06-21, Volume: 7, Issue:13

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Colon; Diet, Sodium-Restricted; Disea

2018
Chronic depression symptoms desensitize renin activity to protect against volume-loading hypertension in Blacks: The SABPA study.
    Physiology & behavior, 2018, 10-01, Volume: 194

    Topics: Adult; Aldosterone; Black People; Blood Pressure; Depression; Female; Glomerular Filtration Rate; Hu

2018
Beneficial effect of combined spironolactone and quinapril treatment on thrombosis and hemostasis in 2K1C hypertensive rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2018, Volume: 69, Issue:2

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antigens, Tumor-Associated, Carbohyd

2018
Inhibition of adenosine deaminase and xanthine oxidase by valproic acid abates hepatic triglyceride accumulation independent of corticosteroids in female rats treated with estrogen-progestin.
    Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:11

    Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Aldosterone; Animals; Contraceptives, Oral, Com

2018
[Efficacy of Screening and Confirmatory Tests of Primary Aldosteronism in Diagnosing Aldosterone Producing Adenoma].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2018, Volume: 49, Issue:3

    Topics: Adenoma; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Retrospective Studies

2018
Untangling Essential Hypertension: The Potential Roles of Aldosterone and Atrial Natriuretic Peptide.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:8

    Topics: Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Essential Hypertension; Humans; Hyp

2018
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:8

    Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L

2018
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:8

    Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L

2018
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:8

    Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L

2018
Aldosterone, Hypertension, and Antihypertensive Therapy: Insights From a General Population.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:8

    Topics: Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Cholesterol, L

2018
Spectrum of renin angiotensin aldosterone system disorders in young hypertensives.
    JPMA. The Journal of the Pakistan Medical Association, 2018, Volume: 68, Issue:8

    Topics: Adolescent; Adult; Aldosterone; Blood Gas Analysis; Cross-Sectional Studies; Electrolytes; Humans; H

2018
Aldosterone LC-MS/MS Assay-Specific Threshold Values in Screening and Confirmatory Testing for Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2018, 11-01, Volume: 103, Issue:11

    Topics: Adult; Aged; Aldosterone; Chromatography, High Pressure Liquid; Diagnostic Techniques, Endocrine; Fe

2018
Aldosterone overload: An overlooked cause of high blood pressure?
    Harvard heart letter : from Harvard Medical School, 2018, Volume: 28, Issue:12

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

2018
Relationship between water and salt intake, osmolality, vasopressin, and aldosterone in the regulation of blood pressure.
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:10

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Osmolar Concentration; Sodium Chloride, Dietary;

2018
Adrenal Vein Sampling Lateralization Despite Mineralocorticoid Receptor Antagonists Exposure in Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2019, 02-01, Volume: 104, Issue:2

    Topics: Adrenal Glands; Adult; Aged; Aldosterone; Blood Specimen Collection; False Negative Reactions; Femal

2019
Renin-producing germ cell tumor in the pineal apparatus and mediastinum: A rare case report.
    Journal of cancer research and therapeutics, 2018, Volume: 14, Issue:Supplement

    Topics: Adult; Aldosterone; Craniotomy; Humans; Hypertension; Male; Mediastinal Neoplasms; Neoplasms, Germ C

2018
The eNOS-NO pathway attenuates kidney dysfunction via suppression of inflammasome activation in aldosterone-induced renal injury model mice.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Aldosterone; Animals; Antihypertensive Agents; Disease Models, Animal; Endothelium; Fibrosis; Humans

2018
Increased Fibroblast Growth Factor 23 in Heart Failure: Biomarker, Mechanism, or Both?
    American journal of hypertension, 2019, 01-01, Volume: 32, Issue:1

    Topics: Aldosterone; Biomarkers; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Heart Failure; Huma

2019
Cellular and Genetic Causes of Idiopathic Hyperaldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 72, Issue:4

    Topics: Aldosterone; Calcium Channels, L-Type; Cytochrome P-450 CYP11B2; Female; G Protein-Coupled Inwardly-

2018
Endothelial cell mineralocorticoid receptors oppose VEGF-induced gene expression and angiogenesis.
    The Journal of endocrinology, 2019, 01-01, Volume: 240, Issue:1

    Topics: Aldosterone; Animals; Aorta; Cells, Cultured; Desoxycorticosterone Acetate; Disease Models, Animal;

2019
Predictors of confirmatory test results for the diagnosis of primary hyperaldosteronism in hypertensive patients with an aldosterone-to-renin ratio greater than 20. The SHRIMP study.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2019, Volume: 42, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hype

2019
Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study.
    Journal of hypertension, 2019, Volume: 37, Issue:5

    Topics: Adult; Aldosterone; Ankle Brachial Index; Antihypertensive Agents; Blood Pressure; Brachial Artery;

2019
Speckle-Tracking Echocardiographic Layer-Specific Strain Analysis on Subclinical Left Ventricular Dysfunction in Patients With Primary Aldosteronism.
    American journal of hypertension, 2019, 01-15, Volume: 32, Issue:2

    Topics: Adult; Aged; Aldosterone; Asymptomatic Diseases; Biomarkers; Blood Pressure; Case-Control Studies; C

2019
Effects of mineralocorticoid and AT-1 receptor antagonism on the aldosterone-renin ratio (ARR) in primary aldosteronism patients (EMIRA Study): rationale and design.
    Journal of human hypertension, 2019, Volume: 33, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Female; Humans; Hyperaldosteronis

2019
The exaggerated salt-sensitive response in hypertensive transgenic rats (TGR mRen-2) fostered by a normotensive female.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2019, Volume: 42, Issue:4

    Topics: Aldosterone; Animals; Blood Pressure; Female; Hypertension; Kidney; Male; Rats; Rats, Transgenic; Re

2019
Changes in serum and intracardiac fibroblast growth factor 23 during the progression of left ventricular hypertrophy in hypertensive model rats.
    Clinical and experimental nephrology, 2019, Volume: 23, Issue:5

    Topics: Aldosterone; Animals; Bone and Bones; Chronic Kidney Disease-Mineral and Bone Disorder; Disease Mode

2019
Lack of Suppression of Aldosterone Production Leads to Salt-Sensitive Hypertension in Female but Not Male Balb/C Mice.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 72, Issue:6

    Topics: Adrenal Glands; Aldosterone; Angiotensinogen; Animals; Blood Pressure; Female; Hypertension; Male; M

2018
Aldosterone and 18-Oxocortisol Coaccumulation in Aldosterone-Producing Lesions.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 72, Issue:6

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Female; Humans;

2018
Rates of abnormal aldosterone/renin ratio in African-origin compared to European-origin patients: A retrospective study.
    Clinical endocrinology, 2019, Volume: 90, Issue:4

    Topics: Adult; Africa; Aldosterone; Echocardiography; Female; Humans; Hyperaldosteronism; Hypertension; Hypo

2019
Adrenal Tissue-Specific Deletion of TASK Channels Causes Aldosterone-Driven Angiotensin II-Independent Hypertension.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 73, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Hypertension; Male; Mice; Mice, Knockout; Nerve Tissue Protein

2019
Impact of adrenocorticotropic hormone stimulation during adrenal venous sampling on outcomes of primary aldosteronism.
    Journal of hypertension, 2019, Volume: 37, Issue:5

    Topics: Adrenal Glands; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Co

2019
Frequency of Primary Hyperaldosteronism in Young Hypertensives in a Tertiary Care Setting of Rawalpindi.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2019, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Cross-Sectional Studies; Female; Humans; Hyperaldost

2019
Mineralocorticoid Receptor Antagonists.
    Vitamins and hormones, 2019, Volume: 109

    Topics: Aldosterone; Animals; Antihypertensive Agents; Heart Failure; Humans; Hypertension; Mineralocorticoi

2019
Family hyperaldosteronism type I: a clinical case and review of literature.
    Terapevticheskii arkhiv, 2018, Sep-20, Volume: 90, Issue:9

    Topics: Adrenalectomy; Aldosterone; Antihypertensive Agents; Blood Pressure; Corticosterone; Cytochrome P-45

2018
[Two case reports on resistant hypertension].
    Der Internist, 2019, Volume: 60, Issue:5

    Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension

2019
The Aldosterone/Renin Ratio Predicts Cardiometabolic Disorders in Subjects Without Classic Primary Aldosteronism.
    American journal of hypertension, 2019, 04-22, Volume: 32, Issue:5

    Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Cross-Sectional Studies; Disease Progression; Female

2019
Evaluation of Biochemical Conditions Allowing Bypass of Confirmatory Testing in The Workup of Primary Aldosteronism: A Retrospective Study in a French Hypertensive Population.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2019, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Female; Humans; Hyperaldosteronism; Hyperte

2019
[Corticosurrenaloma: an exceptional cause of primary hyperaldosteronism].
    The Pan African medical journal, 2018, Volume: 31

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Glucocorticoids; Hepatectomy; Humans; Hyperaldosteronis

2018
Hypertension in pregnancy: Role of body mass index, insulin resistance, aldosterone, and calcium homeostasis.
    Journal of clinical hypertension (Greenwich, Conn.), 2019, Volume: 21, Issue:5

    Topics: Aldosterone; Body Mass Index; Calcium; China; Cross-Sectional Studies; Female; Homeostasis; Humans;

2019
CaseReport: Aldosterone-secreting adrenal carcinoma complicating longstanding hypertension.
    Journal of human hypertension, 2020, Volume: 34, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Carcinoma; Humans; H

2020
Long-term BP control and vascular health in patients with hyperaldosteronism treated with low-dose, amiloride-based therapy.
    Journal of clinical hypertension (Greenwich, Conn.), 2019, Volume: 21, Issue:7

    Topics: Aftercare; Aldosterone; Amiloride; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitorin

2019
Hypertension with primary aldosteronism is associated with increased carotid intima-media thickness and endothelial dysfunction.
    Journal of clinical hypertension (Greenwich, Conn.), 2019, Volume: 21, Issue:7

    Topics: Aldosterone; Antihypertensive Agents; Brachial Artery; Carotid Arteries; Carotid Intima-Media Thickn

2019
Subclinical atherosclerosis due to increase of plasma aldosterone concentrations in essential hypertensive individuals.
    Journal of hypertension, 2019, Volume: 37, Issue:11

    Topics: Adult; Aldosterone; Ankle Brachial Index; Atherosclerosis; Biomarkers; Carotid Intima-Media Thicknes

2019
Primary Aldosteronism: Does Underlying Pathology Impact Clinical Presentation and Outcomes Following Unilateral Adrenalectomy?
    World journal of surgery, 2019, Volume: 43, Issue:10

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Female; Humans;

2019
Sex Difference in the Association Between Subtype Distribution and Age at Diagnosis in Patients With Primary Aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 74, Issue:2

    Topics: Adrenalectomy; Adult; Age Distribution; Age of Onset; Aged; Aldosterone; Databases, Factual; Female;

2019
The captopril challenge test for diagnosing primary Aldosteronism in a Chinese population.
    BMC endocrine disorders, 2019, Jun-24, Volume: 19, Issue:1

    Topics: Adult; Aldosterone; Captopril; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged;

2019
[Primary hyperaldosteronism in a population of hypertensive patients].
    Medicina, 2019, Volume: 79, Issue:3

    Topics: Aged; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2019
Maintenance of long-term blood pressure control and vascular health by low-dose amiloride-based therapy in hyperaldosteronism.
    Journal of clinical hypertension (Greenwich, Conn.), 2019, Volume: 21, Issue:8

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Albuminuria; Aldosterone; Amiloride; Ankle Brachial Index;

2019
Excess Arterial Damage in Hyperaldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 74, Issue:3

    Topics: Aldosterone; Arteries; Humans; Hyperaldosteronism; Hypertension

2019
Aldosterone Induces Vascular Damage.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 74, Issue:3

    Topics: Adult; Aldosterone; Antihypertensive Agents; Area Under Curve; Arterial Pressure; Cohort Studies; Cr

2019
Body mass index predicts aldosterone production in hypertensive postmenopausal women.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2020, Volume: 42, Issue:3

    Topics: Adult; Aldosterone; Body Mass Index; China; Correlation of Data; Cross-Sectional Studies; Estrogens;

2020
Familial hyperkalemia and hypertension and a hypothesis to explain proximal renal tubular acidosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 08-13, Volume: 116, Issue:33

    Topics: Acidosis, Renal Tubular; Aldosterone; Chlorides; Humans; Hyperkalemia; Hypertension; Protein Serine-

2019
The changing spectrum of hypertension in premature infants.
    Journal of perinatology : official journal of the California Perinatal Association, 2019, Volume: 39, Issue:11

    Topics: Aldosterone; Antihypertensive Agents; Creatinine; Female; Humans; Hypertension; Infant, Low Birth We

2019
Urinary sodium excretion is the main determinant of mineralocorticoid excretion rates in patients with chronic kidney disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2013, Volume: 28, Issue:6

    Topics: Aldosterone; Cohort Studies; Corticosterone; Cross-Sectional Studies; Essential Hypertension; Female

2013
Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension.
    Nature genetics, 2013, Volume: 45, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Calcium; Cells, Cultured; Electrophys

2013
Regression of albuminuria and hypertension and arrest of severe renal injury by a losartan-hydrochlorothiazide association in a model of very advanced nephropathy.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Acute Kidney Injury; Albuminuria; Aldosterone; Animals; Antihypertensive Agents; Drug Therapy, Combi

2013
Predominance of AT(1) blockade over mas-mediated angiotensin-(1-7) mechanisms in the regulation of blood pressure and renin-angiotensin system in mRen2.Lewis rats.
    American journal of hypertension, 2013, Volume: 26, Issue:5

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihy

2013
Factors affecting complete hypertension cure after adrenalectomy for aldosterone-producing adenoma: outcomes in a large series.
    Urologia internationalis, 2013, Volume: 90, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Antihypertensive Agents; Blood

2013
Blood pressure variability activates cardiac mineralocorticoid receptor and induces cardiac remodeling in hypertensive rats.
    Circulation journal : official journal of the Japanese Circulation Society, 2013, Volume: 77, Issue:6

    Topics: Active Transport, Cell Nucleus; Aldosterone; Animals; Blood Pressure; Cardiomegaly; Cell Nucleus; Ep

2013
Aldosterone levels and inflammatory stimulation in essential hypertensive patients.
    Journal of human hypertension, 2013, Volume: 27, Issue:9

    Topics: Adult; Aged; Aldosterone; Biomarkers; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; C

2013
Medical or surgical therapy for primary aldosteronism: post-treatment follow-up as a surrogate measure of comparative outcomes.
    Annals of surgical oncology, 2013, Volume: 20, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Antihypertensiv

2013
Additional antihypertensive effect of magnesium supplementation with an angiotensin II receptor blocker in hypomagnesemic rats.
    The Korean journal of internal medicine, 2013, Volume: 28, Issue:2

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agen

2013
Aldosterone excess impairs first phase insulin secretion in primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:6

    Topics: Adult; Aldosterone; Blood Glucose; Female; Humans; Hyperaldosteronism; Hypertension; Insulin; Insuli

2013
Hormones other than aldosterone may contribute to hypertension in 3 different subtypes of primary aldosteronism.
    Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:4

    Topics: Adrenal Medulla; Adult; Aldosterone; Blood Pressure Determination; Female; Glucocorticoids; Humans;

2013
Serum dehydroepiandrosterone sulfate concentration is lower in women with primary aldosteronism.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2015, Volume: 16, Issue:1

    Topics: Adenoma; Adult; Aged; Aldosterone; Cholesterol, HDL; Creatinine; Dehydroepiandrosterone Sulfate; Ess

2015
High sodium intake is associated with increased glucocorticoid production, insulin resistance and metabolic syndrome.
    Clinical endocrinology, 2014, Volume: 80, Issue:5

    Topics: Adiponectin; Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Blood Glucose; Body Mass Index

2014
Rhabdomyolysis presenting with severe hypokalemia in hypertensive patients: a case series.
    BMC research notes, 2013, Apr-17, Volume: 6

    Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperald

2013
Renin angiotensin antagonists normalize aberrant activation of epithelial sodium channels in sodium-sensitive hypertension.
    Nephron. Experimental nephrology, 2012, Volume: 122, Issue:3-4

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Do

2012
Hypertension and depressed symptomatology: a cluster related to the activation of the renin-angiotensin-aldosterone system (RAAS). Findings from population based KORA F4 study.
    Psychoneuroendocrinology, 2013, Volume: 38, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Cross-Sectional Studies; Depression; Female; Germany; H

2013
Estrogen receptor-β in the paraventricular nucleus and rostroventrolateral medulla plays an essential protective role in aldosterone/salt-induced hypertension in female rats.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:6

    Topics: Aldosterone; Animals; Animals, Newborn; Blood Pressure; Cells, Cultured; Disease Models, Animal; Est

2013
Spironolactone prevents dietary-induced metabolic syndrome by inhibiting PI3-K/Akt and p38MAPK signaling pathways.
    Journal of endocrinological investigation, 2013, Volume: 36, Issue:11

    Topics: Aldosterone; Animals; Apoptosis; Diet, High-Fat; Dyslipidemias; Hypertension; Insulin-Secreting Cell

2013
Novel mechanism for disrupted circadian blood pressure rhythm in a rat model of metabolic syndrome--the critical role of angiotensin II.
    Journal of the American Heart Association, 2013, Apr-29, Volume: 2, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Circadian Rhythm; Disease Models, Animal; Hype

2013
Bone health and aldosterone excess.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2013, Volume: 24, Issue:11

    Topics: Absorptiometry, Photon; Adult; Aged; Aldosterone; Bone Density; Calcium; Essential Hypertension; Fem

2013
Prevalence and clinical characteristics of primary aldosteronism in Japanese patients with type 2 diabetes mellitus and hypertension.
    Endocrine journal, 2013, Volume: 60, Issue:8

    Topics: Aged; Aldosterone; Angiotensin Receptor Antagonists; Antihypertensive Agents; Asian People; Diabetes

2013
Incidence and factors of post-adrenalectomy hyperkalemia in patients with aldosterone producing adenoma.
    Clinica chimica acta; international journal of clinical chemistry, 2013, Sep-23, Volume: 424

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Female; H

2013
[Effect of Rhodiola Sacra on left ventricular remodeling and its mechanism in spontaneously hypertensive rats].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2013, Volume: 44, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Drugs, Chinese Herbal; Hypertension; Male; Rats; Rats, Inbred

2013
Echocardiographic effects of eplerenone and aldosterone in hypertensive rats.
    Frontiers in bioscience (Elite edition), 2013, 06-01, Volume: 5, Issue:3

    Topics: Aldosterone; Animals; Echocardiography; Eplerenone; Hypertension; Male; Rats; Rats, Inbred SHR; Rats

2013
Bimodal aldosterone distribution in low-renin hypertension.
    American journal of hypertension, 2013, Volume: 26, Issue:9

    Topics: Aged; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2013
Inadequate RAAS suppression is associated with excessive left ventricular mass and systo-diastolic dysfunction.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2013, Volume: 102, Issue:10

    Topics: Adult; Aldosterone; Blood Pressure Monitoring, Ambulatory; Cross-Sectional Studies; Echocardiography

2013
Primary aldosteronism: emerging trends.
    Trends in endocrinology and metabolism: TEM, 2013, Volume: 24, Issue:9

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Renin

2013
Central endogenous angiotensin-(1-7) protects against aldosterone/NaCl-induced hypertension in female rats.
    American journal of physiology. Heart and circulatory physiology, 2013, Sep-01, Volume: 305, Issue:5

    Topics: Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models

2013
Comparison of 24-h urinary aldosterone level and random urinary aldosterone-to-creatinine ratio in the diagnosis of primary aldosteronism.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Creatinine; Essential Hypertension; Female; Hu

2013
Quantification of urinary 18-hydroxycortisol using LC-MS/MS.
    Annals of clinical biochemistry, 2013, Volume: 50, Issue:Pt 5

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Biomarkers, Tumor; Chromatography, Liquid; Essential

2013
Stimulation of aldosterone synthesis by angiotensin II in the brain: support for positive feedback in hypertension?
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 62, Issue:3

    Topics: Aldosterone; Animals; Brain; Corticosterone; Hypertension; Male

2013
Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 62, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Brain; Corticosterone; Cytochrome P-450 CYP11B

2013
Synergic effect of high renin and aldosterone levels on inappropriate left ventricular mass and systolic function: a tissue Doppler study.
    International journal of cardiology, 2013, Oct-12, Volume: 168, Issue:5

    Topics: Adult; Aldosterone; Biomarkers; Echocardiography, Doppler; Female; Humans; Hypertension; Male; Renin

2013
Nebivolol: a multifaceted antioxidant and cardioprotectant in hypertensive heart disease.
    Journal of cardiovascular pharmacology, 2013, Volume: 62, Issue:5

    Topics: Aldosterone; Animals; Antioxidants; Benzopyrans; Calcium; Cardiotonic Agents; Cytosol; Disease Model

2013
Complement 3 activates the renal renin-angiotensin system by induction of epithelial-to-mesenchymal transition of the nephrotubulus in mice.
    American journal of physiology. Renal physiology, 2013, Oct-01, Volume: 305, Issue:7

    Topics: Aldosterone; Amides; Angiotensin II; Animals; Antihypertensive Agents; Complement C3; Epithelial-Mes

2013
NT-proBNP, a useful tool in hypertensive patients undergoing a diagnostic evaluation for primary aldosteronism.
    Endocrine, 2014, Volume: 45, Issue:3

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Natriuretic

2014
Female sex hormones are associated with the reduction of serum sodium and hypertension complications in patients with aldosterone-producing adenoma.
    Endocrine journal, 2013, Volume: 60, Issue:11

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Biomarkers; Cerebrovascular Disorders;

2013
Blood pressure control 1 year after referral to a hypertension specialist.
    Journal of clinical hypertension (Greenwich, Conn.), 2013, Volume: 15, Issue:9

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Cohort Studies; Female; Follow-Up

2013
Effects of salt status and blockade of mineralocorticoid receptors on aldosterone-induced cardiac injury.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2014, Volume: 37, Issue:2

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Echocardiography; Endoth

2014
Lethal liquorice lollies (liquorice abuse causing pseudohyperaldosteronism).
    BMJ case reports, 2013, 09-19, Volume: 2013

    Topics: Aldosterone; Diagnosis, Differential; Electrocardiography; Female; Follow-Up Studies; Glycyrrhiza; H

2013
Evaluation of docosahexaenoic acid in a dog model of hypertension induced left ventricular hypertrophy.
    Journal of cardiovascular translational research, 2013, Volume: 6, Issue:6

    Topics: Aldosterone; Animals; Arachidonic Acid; Blood Pressure; Disease Models, Animal; Docosahexaenoic Acid

2013
Prognosis of primary aldosteronism in Japan: results from a nationwide epidemiological study.
    Endocrine journal, 2014, Volume: 61, Issue:1

    Topics: Adenoma; Aldosterone; Epidemiologic Studies; Female; Health Surveys; Humans; Hyperaldosteronism; Hyp

2014
Combined antihypertensive effect of luteolin and buddleoside enriched extracts in spontaneously hypertensive rats.
    Journal of ethnopharmacology, 2013, Nov-25, Volume: 150, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Drug Therapy, Combination; Endothelin

2013
Somatic ATP1A1, ATP2B3, and KCNJ5 mutations in aldosterone-producing adenomas.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Cytochrome P-450 CYP11B2; Fema

2014
Telmisartan delays myocardial fibrosis in rats with hypertensive left ventricular hypertrophy by TGF-β1/Smad signal pathway.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2014, Volume: 37, Issue:1

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzo

2014
Blood pressure and neurohormonal responses to renal nerve ablation in treatment-resistant hypertension.
    Journal of hypertension, 2014, Volume: 32, Issue:1

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Denervati

2014
Cushing's disease and hypertension: in vivo and in vitro study of the role of the renin-angiotensin-aldosterone system and effects of medical therapy.
    European journal of endocrinology, 2014, Volume: 170, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensinogen; Animals; Cabergoline; Ergolines; Female; Humans; Hyperten

2014
Aldosterone blockade reduces mortality without changing cardiac remodeling in spontaneously hypertensive rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2013, Volume: 32, Issue:5

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Electrocardiography; Gene Expression Regulation; Hy

2013
[Correlation between plasma aldosterone concentration and left ventricular structure in hypertensive patients].
    Zhonghua xin xue guan bing za zhi, 2013, Volume: 41, Issue:7

    Topics: Adolescent; Adult; Aged; Aldosterone; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, L

2013
Aldosterone testing: evaluation of a novel automated immunoassay.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2014, Volume: 19, Issue:1

    Topics: Aldosterone; Case-Control Studies; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Limit of D

2014
Smooth muscle cell mineralocorticoid receptors are mandatory for aldosterone-salt to induce vascular stiffness.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Male; Mice; Mice, Transg

2014
Renal denervation: still more questions than answers.
    Journal of hypertension, 2014, Volume: 32, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Denervation; Endothelin-1; Humans; Hypertensio

2014
Long-term prehypertension treatment with losartan effectively prevents brain damage and stroke in stroke-prone spontaneously hypertensive rats.
    International journal of molecular medicine, 2014, Volume: 33, Issue:2

    Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Apoptosis; Blood Pressure; Brain; Hypertension; Lo

2014
M-atrial natriuretic peptide and nitroglycerin in a canine model of experimental acute hypertensive heart failure: differential actions of 2 cGMP activating therapeutics.
    Journal of the American Heart Association, 2014, Jan-02, Volume: 3, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Arterial Pressure; Atrial Natriuretic Factor; Cardiac Pacing,

2014
Modulation of aldosterone levels by -344 C/T CYP11B2 polymorphism and spironolactone use in resistant hypertension.
    Journal of the American Society of Hypertension : JASH, 2014, Volume: 8, Issue:3

    Topics: Aged; Aldosterone; Alleles; Blood Pressure; Cytochrome P-450 CYP11B2; DNA; Female; Genotype; Humans;

2014
Reninoma: the importance of renal vein renin ratios for lateralisation and diagnosis.
    American journal of nephrology, 2014, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Antihypertensive Agents; Captopril; Enalaprilat; Female; Humans; Hyp

2014
[Analysis of characteristics of renin, aldosterone and aldosterone/renin ratio in patients with aldosterone-producing adenoma].
    Zhonghua yi xue za zhi, 2013, Nov-12, Volume: 93, Issue:42

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Case-Control Studies; Essential Hypertension; Female; H

2013
Autocrine and paracrine function of Angiotensin 1-7 in tissue repair during hypertension.
    American journal of hypertension, 2014, Volume: 27, Issue:6

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Aut

2014
Renin-angiotensin-aldosterone-blockade is associated with decreased use of antidepressant therapy in patients with type 1 diabetes and diabetic nephropathy.
    Acta diabetologica, 2014, Volume: 51, Issue:4

    Topics: Adult; Aged; Aldosterone; Angiotensins; Antidepressive Agents; Antihypertensive Agents; Cross-Sectio

2014
Methylglyoxal, a reactive glucose metabolite, increases renin angiotensin aldosterone and blood pressure in male Sprague-Dawley rats.
    American journal of hypertension, 2014, Volume: 27, Issue:3

    Topics: Aldosterone; Angiotensins; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Catecholami

2014
Association of renin and aldosterone with ethnicity and blood pressure: the Multi-Ethnic Study of Atherosclerosis.
    American journal of hypertension, 2014, Volume: 27, Issue:6

    Topics: Aged; Aged, 80 and over; Aldosterone; Asian People; Atherosclerosis; Biomarkers; Black or African Am

2014
Measurement of plasma renin concentration instead of plasma renin activity decreases the positive aldosterone-to-renin ratio tests in treated patients with essential hypertension.
    Journal of hypertension, 2014, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Blood Chemical Ana

2014
Exploring the role of aldosterone in right ventricular function.
    The Canadian journal of cardiology, 2014, Volume: 30, Issue:2

    Topics: Aldosterone; Blood Pressure; Female; Heart Ventricles; Humans; Hypertension; Male; Renin; Renin-Angi

2014
Abnormal regulation of renin angiotensin aldosterone system is associated with right ventricular dysfunction in hypertension.
    The Canadian journal of cardiology, 2014, Volume: 30, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Echocardiography, Doppler; Female; Heart Ventricles; Humans; Hyp

2014
Is adrenal venous sampling mandatory before surgical decision in case of primary hyperaldosteronism?
    World journal of surgery, 2014, Volume: 38, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Blood Pressure;

2014
Corticosterone-activated mineralocorticoid receptor contributes to salt-induced sympathoexcitation in pressure overload mice.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:8

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenalectomy; Aldosterone; Animals; Corticosterone; Hy

2014
Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma.
    Molecular bioSystems, 2014, Volume: 10, Issue:6

    Topics: Adenoma; Adrenal Glands; Adult; Aged; Aldosterone; Antigens, Neoplasm; Biomarkers; Case-Control Stud

2014
[Influence factors of salt-sensitive hypertension and responses of blood pressure and urinary sodium and potassium excretion to acute oral saline loading among essential hypertensive patients].
    Zhonghua xin xue guan bing za zhi, 2013, Volume: 41, Issue:12

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Electrolytes; Essential Hypertension; Female; Humans; Hype

2013
Aldosterone to active Renin ratio as screening test for primary aldosteronism: reproducibility and influence of orthostasis and salt loading.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2014, Volume: 46, Issue:6

    Topics: Aldosterone; Cohort Studies; Dizziness; Essential Hypertension; Female; Humans; Hyperaldosteronism;

2014
Endothelial cell mineralocorticoid receptors regulate deoxycorticosterone/salt-mediated cardiac remodeling and vascular reactivity but not blood pressure.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:5

    Topics: Aldosterone; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cells, Cultured; Conne

2014
Adiponectin as an independent predictor of left ventricular hypertrophy in nondiabetic patients with hypertension.
    Angiology, 2015, Volume: 66, Issue:3

    Topics: Adiponectin; Aged; Aldosterone; Biomarkers; Female; Hemodynamics; Humans; Hypertension; Hypertrophy,

2015
Aldosterone receptor blockers spironolactone and canrenone: two multivalent drugs.
    Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:7

    Topics: Albuminuria; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Canrenone; Humans; Hypertension;

2014
Hypokalaemia in a hyperthyroid domestic shorthair cat with adrenal hyperplasia.
    Journal of feline medicine and surgery, 2014, Volume: 16, Issue:10

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Aldosterone; Amlodipine; Animals; Carbimazole; Cat Dis

2014
The unique response of renin and aldosterone to dietary sodium intervention in sodium sensitivity.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2014, Volume: 15, Issue:2

    Topics: Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Age

2014
Effect of obstructive respiratory events on blood pressure and renal perfusion in a pig model for sleep apnea.
    American journal of hypertension, 2014, Volume: 27, Issue:10

    Topics: Aldosterone; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Creatinine; Disea

2014
The velocity of home blood pressure reduction in response to low-dose eplerenone combined with other antihypertensive drugs determined by exponential decay function analysis.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure

2014
Aldosterone-to-renin ratio and nocturnal blood pressure decline assessed by self-measurement of blood pressure at home: the Ohasama Study.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure

2014
Primary aldosteronism and essential hypertension: assessment of cardiovascular risk at diagnosis and after treatment.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2014, Volume: 24, Issue:5

    Topics: Adult; Aged; Aldosterone; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Essential Hyperten

2014
Urinary angiotensinogen as a potential biomarker of intrarenal renin-angiotensin system activity in Chinese chronic kidney disease patients.
    Irish journal of medical science, 2015, Volume: 184, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Angiotensinogen; Asian Peop

2015
Aldosterone to active renin ratio is associated with nocturnal blood pressure in obese and treated hypertensive patients: the Styrian Hypertension Study.
    Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:4

    Topics: Aged; Aldosterone; Antihypertensive Agents; Austria; Blood Pressure; Blood Pressure Monitoring, Ambu

2014
Negative association between plasma aldosterone concentration/plasma renin activity and morning blood pressure surge in never-treated hypertensive patients.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:4

    Topics: Aldosterone; Ankle Brachial Index; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory

2014
Adiponectin and Aldosterone in Left Ventricular Hypertrophy: An Intriguing Interplay.
    Angiology, 2018, Volume: 69, Issue:9

    Topics: Adiponectin; Aldosterone; Humans; Hypertension; Hypertrophy, Left Ventricular

2018
CNS neuroplasticity and salt-sensitive hypertension induced by prior treatment with subpressor doses of ANG II or aldosterone.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Jun-15, Volume: 306, Issue:12

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain; Brain-Derived

2014
Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and exacerbates angiotensin II-mediated hypertension.
    Kidney international, 2014, Volume: 86, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Aldosterone; Angiotensin II; Angiotensinogen; Animals; Blood P

2014
Mizoribine ameliorates renal injury and hypertension along with the attenuation of renal caspase-1 expression in aldosterone-salt-treated rats.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Aldosterone; Animals; Blood Pressure; Caspase 1; DNA Nucleotidylexotransferase; Epithelial Sodium Ch

2014
[Suppression test to diagnose hyperaldosteronism in cats].
    Tijdschrift voor diergeneeskunde, 2014, Mar-01, Volume: 139, Issue:3

    Topics: Aldosterone; Animals; Cat Diseases; Cats; Hyperaldosteronism; Hypertension

2014
Racial differences in sensitivity of blood pressure to aldosterone.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Analysis of Variance; Anti-Inflammatory Agents; Black or African Ame

2014
Heme oxygenase suppresses markers of heart failure and ameliorates cardiomyopathy in L-NAME-induced hypertension.
    European journal of pharmacology, 2014, Jul-05, Volume: 734

    Topics: Adiponectin; Aldosterone; Animals; Antioxidants; Arginine; Atrial Natriuretic Factor; Biomarkers; Bl

2014
Adipokines: another link between obesity and hypertension.
    Journal of human hypertension, 2015, Volume: 29, Issue:3

    Topics: Aldosterone; Humans; Hypertension; Obesity

2015
Editorial: New horizon in the treatment of hypertension--role for Ca channel blockers--why do Ca channel blockers be focused on?
    Current hypertension reviews, 2013, Volume: 9, Issue:3

    Topics: Aldosterone; Calcium Channel Blockers; Edema; Heart; Humans; Hypertension; Renal Insufficiency, Chro

2013
KCNJ5 gene somatic mutations affect cardiac remodelling but do not preclude cure of high blood pressure and regression of left ventricular hypertrophy in primary aldosteronism.
    Journal of hypertension, 2014, Volume: 32, Issue:7

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Female; Follow-Up Studies; G Protein-

2014
Small dedifferentiated cardiomyocytes bordering on microdomains of fibrosis: evidence for reverse remodeling with assisted recovery.
    Journal of cardiovascular pharmacology, 2014, Volume: 64, Issue:3

    Topics: Aldosterone; Animals; Antioxidants; Cell Dedifferentiation; Cell Differentiation; Fibrosis; Hyperten

2014
Reduction of plasma aldosterone and arterial stiffness in obese pre- and stage1 hypertensive subjects after aerobic exercise.
    Journal of human hypertension, 2015, Volume: 29, Issue:1

    Topics: Aldosterone; Biomarkers; Blood Pressure; Down-Regulation; Exercise Therapy; Female; Humans; Hyperten

2015
[Farmacological effect of retabolil on aldosterone level and arterial pressure in rats under the action of vibrations].
    Eksperimental'naia i klinicheskaia farmakologiia, 2014, Volume: 77, Issue:3

    Topics: Aldosterone; Anabolic Agents; Animals; Arterial Pressure; Hypertension; Male; Mineralocorticoid Rece

2014
Clinical outcomes in patients undergoing laparoscopic adrenalectomy for unilateral aldosterone producing adenoma: partial versus total adrenalectomy.
    Journal of endourology, 2014, Volume: 28, Issue:9

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Blood Pressure; Female; H

2014
Lack of RAAS inhibition by high-salt intake is associated with arterial stiffness in hypertensive patients.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2014, Volume: 15, Issue:4

    Topics: Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System; Sodiu

2014
High-probability features of primary aldosteronism may obviate the need for confirmatory testing without increasing false-positive diagnoses.
    Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:7

    Topics: Adrenal Glands; Adult; Aldosterone; False Positive Reactions; Female; Humans; Hydrocortisone; Hypera

2014
Association between urine aldosterone and diastolic function in patients with primary aldosteronism and essential hypertension.
    Clinical biochemistry, 2014, Volume: 47, Issue:13-14

    Topics: Adult; Aldosterone; Echocardiography; Essential Hypertension; Female; Humans; Hyperaldosteronism; Hy

2014
Primary aldosteronism in hypertensive patients: clinical implications and target therapy.
    European journal of clinical investigation, 2014, Volume: 44, Issue:8

    Topics: Adrenocorticotropic Hormone; Aldosterone; Antihypertensive Agents; Case-Control Studies; Female; Hum

2014
Hypotensive effect of retabolil correcting the concentration of aldosterone during stress exposures.
    Bulletin of experimental biology and medicine, 2014, Volume: 157, Issue:2

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Male; Nandrolone; Nandr

2014
Association of aldosterone-to-renin ratio with hypertension differs by sodium intake: the Ohasama study.
    American journal of hypertension, 2015, Volume: 28, Issue:2

    Topics: Aged; Aldosterone; Female; Humans; Hypertension; Incidence; Japan; Longitudinal Studies; Male; Middl

2015
Oxidative stress in patients affected by primary aldosteronism.
    Journal of hypertension, 2014, Volume: 32, Issue:10

    Topics: Adenoma; Adrenalectomy; Adult; Aged; Aldosterone; Essential Hypertension; Female; Humans; Hyperaldos

2014
Aldosterone-renin ratio in the assessment of primary aldosteronism.
    JAMA, 2014, Volume: 312, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism;

2014
The blood pressure-lowering effect of renal denervation is inversely related to kidney function.
    Journal of hypertension, 2014, Volume: 32, Issue:10

    Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; C

2014
The value of losartan suppression test in the confirmatory diagnosis of primary aldosteronism in patients over 50 years old.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2015, Volume: 16, Issue:3

    Topics: Aldosterone; Captopril; Demography; Female; Humans; Hyperaldosteronism; Hypertension; Losartan; Male

2015
Increased salt intake during early ontogenesis lead to development of arterial hypertension in salt-resistant Wistar rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Aldosterone; Animals; Blood Pressure; Blotting, Western; Disea

2015
A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:9

    Topics: Adenoma; Adrenal Cortex; Adrenocortical Adenoma; Aged; Aldosterone; Antihypertensive Agents; Cell Li

2014
Introgressed chromosome 2 quantitative trait loci restores aldosterone regulation and reduces response to salt in the stroke-prone spontaneously hypertensive rat.
    Journal of hypertension, 2014, Volume: 32, Issue:10

    Topics: Aldosterone; Animals; Chromosomes; Genotype; Hypertension; Kidney; Male; Quantitative Trait Loci; Ra

2014
Albumin may prevent hypertension by inhibiting renin angiotensin aldosterone system.
    International journal of cardiology, 2014, Oct-20, Volume: 176, Issue:3

    Topics: Aldosterone; Cohort Studies; Female; Humans; Hypertension; Japan; Male; Potassium; Renin-Angiotensin

2014
Vitamin D modulates the association of circulating insulin-like growth factor-1 with carotid artery intima-media thickness.
    Atherosclerosis, 2014, Volume: 236, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Albuminuria; Aldosterone; Apoptosis; Baltimore; Body Mass Index; Car

2014
The influence of aging on the diagnosis of primary aldosteronism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2014, Volume: 37, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captop

2014
RAAS and stress markers in acute ischemic stroke: preliminary findings.
    Acta neurologica Scandinavica, 2015, Volume: 131, Issue:2

    Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Animals; Biomarkers; Blood Pressure; Female; H

2015
Synergic effects of renin and aldosterone on right ventricular function in hypertension: a tissue Doppler study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2015, Volume: 16, Issue:12

    Topics: Adult; Aldosterone; Anthropometry; Biomarkers; Echocardiography, Doppler; Female; Heart Ventricles;

2015
Decreased plasma prorenin levels in primary aldosteronism: potential diagnostic implications.
    Journal of hypertension, 2015, Volume: 33, Issue:1

    Topics: Adenoma; Adult; Aldosterone; Cohort Studies; Essential Hypertension; Female; Humans; Hyperaldosteron

2015
Primary aldosteronism: functional histopathology and long-term follow-up after unilateral adrenalectomy.
    Clinical endocrinology, 2015, Volume: 82, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Cytochrome P-

2015
Beneficial effects of proanthocyanidins in the cardiac alterations induced by aldosterone in rat heart through mineralocorticoid receptor blockade.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Aldosterone; Animals; Cell Line; Chlorocebus aethiops; Heart; Hypertension; Immediate-Early Proteins

2014
[How to unravel hyperaldosteronism in clinical practice].
    MMW Fortschritte der Medizin, 2014, Oct-09, Volume: 156, Issue:17

    Topics: Aldosterone; Algorithms; Antihypertensive Agents; Diagnosis, Differential; Drug Resistance; Humans;

2014
Aldosteronoma resolution score predicts long-term resolution of hypertension.
    Surgery, 2014, Volume: 156, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure Determination; C

2014
Effects of cilnidipine on sympathetic nerve activity and cardiorenal function in hypertensive patients with type 2 diabetes mellitus: association with BNP and aldosterone levels.
    Diabetes research and clinical practice, 2014, Volume: 106, Issue:3

    Topics: Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, T

2014
Renal BOLD-MRI relates to kidney function and activity of the renin-angiotensin-aldosterone system in hypertensive patients.
    Journal of hypertension, 2015, Volume: 33, Issue:3

    Topics: Aged; Aldosterone; Blood Pressure; Creatinine; Female; Glomerular Filtration Rate; Humans; Hypertens

2015
Inhibitory effect of D3 dopamine receptor on migration of vascular smooth muscle cells induced by synergistic effect of angiotensin II and aldosterone.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:4

    Topics: Aldosterone; Angiotensin II; Aorta, Thoracic; Cell Movement; Cells, Cultured; Drug Synergism; Humans

2015
[24-hour systolic wave increment index monitoring in patients with low-renin arterial hypertension].
    Terapevticheskii arkhiv, 2014, Volume: 86, Issue:9

    Topics: Adult; Aldosterone; Arteries; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhyth

2014
Should aldosterone suppression tests be conducted during a particular phase of the menstrual cycle, and, if so, which phase? Results of a preliminary study.
    Clinical endocrinology, 2015, Volume: 83, Issue:3

    Topics: Adult; Aldosterone; Chromatography, High Pressure Liquid; Diagnostic Techniques, Endocrine; Estradio

2015
Aldosterone Levels, Aortic Stiffness, and Wave Reflection in Essential Hypertensive Patients.
    American journal of hypertension, 2015, Volume: 28, Issue:7

    Topics: Adult; Aldosterone; Biomarkers; Female; Humans; Hypertension; Male; Middle Aged; Predictive Value of

2015
Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; A

2014
Plasma aldosterone and its relationship with left ventricular mass in hypertensive patients with early-stage chronic kidney disease.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:4

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Creatinine; Female; Humans; Hypertension; Hypertrophy, Lef

2015
Effect of aldosterone-producing adenoma on endothelial function and Rho-associated kinase activity in patients with primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:4

    Topics: Adenoma; Adult; Aldosterone; Blood Pressure; Endothelium, Vascular; Female; Follow-Up Studies; Human

2015
Expression and functional role of the prorenin receptor in the human adrenocortical zona glomerulosa and in primary aldosteronism.
    Journal of hypertension, 2015, Volume: 33, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aldosterone; Animals; Case-Control Studies

2015
Iron restriction inhibits renal injury in aldosterone/salt-induced hypertensive mice.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:5

    Topics: Aldosterone; Animals; Hypertension; Iron, Dietary; Kidney Diseases; Male; Mice; Mice, Inbred C57BL;

2015
Primary aldosteronism and its various clinical scenarios.
    Journal of hypertension, 2015, Volume: 33, Issue:6

    Topics: Adult; Aged; Aldosterone; Cardiovascular Diseases; Female; Humans; Hyperaldosteronism; Hypertension;

2015
Importance of contralateral aldosterone suppression during adrenal vein sampling in the subtype evaluation of primary aldosteronism.
    Clinical endocrinology, 2015, Volume: 83, Issue:4

    Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Retrospective Stud

2015
Unadjusted Plasma Renin Activity as a "First-Look" Test to Decide Upon Further Investigations for Primary Aldosteronism.
    Journal of clinical hypertension (Greenwich, Conn.), 2015, Volume: 17, Issue:7

    Topics: Adult; Aldosterone; Antihypertensive Agents; Body Mass Index; Female; Humans; Hyperaldosteronism; Hy

2015
Plasma aldosterone concentration is positively associated with pulse pressure in patients with primary hypertension.
    Medicine, 2015, Volume: 94, Issue:10

    Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Logistic Models; Male; Middle Aged

2015
Aldosterone and abnormal left ventricular geometry in chronic kidney disease.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:5

    Topics: Aldosterone; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Renal Insufficiency,

2015
Plasma aldosterone and left ventricular diastolic function in treatment-naïve patients with hypertension: tissue-Doppler imaging study.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:6

    Topics: Adult; Aldosterone; Analysis of Variance; Case-Control Studies; Chi-Square Distribution; Diastole; E

2015
Reliability of a Bayesian network to predict an elevated aldosterone-to-renin ratio.
    Archives of cardiovascular diseases, 2015, Volume: 108, Issue:5

    Topics: Adult; Aldosterone; Bayes Theorem; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Ag

2015
Global- and renal-specific sympathoinhibition in aldosterone hypertension.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:6

    Topics: Aldosterone; Analysis of Variance; Animals; Baroreflex; Blood Pressure; Disease Models, Animal; Dogs

2015
Impact of global versus renal-specific sympathoinhibition in aldosterone-induced hypertension: implications for medical device-based treatment of resistant hypertension.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:6

    Topics: Aldosterone; Animals; Baroreflex; Hypertension; Male; Norepinephrine; Renin-Angiotensin System

2015
Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism.
    eLife, 2015, Apr-24, Volume: 4

    Topics: Adolescent; Adult; Age of Onset; Aldosterone; Amino Acid Sequence; Calcium; Calcium Channels, T-Type

2015
Cost-Effectiveness of Therapeutic Drug Monitoring in Diagnosing Primary Aldosteronism in Patients With Resistant Hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2015, Volume: 17, Issue:9

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Cost-Benefit Analysis;

2015
Stress-induced Aldosterone Hyper-Secretion in a Substantial Subset of Patients With Essential Hypertension.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:8

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Case-Control Studies; Cy

2015
Mineralocorticoid exposure and receptor activity modulate microvascular endothelial function in African Americans with and without hypertension.
    Vascular medicine (London, England), 2015, Volume: 20, Issue:5

    Topics: Adult; Aldosterone; Black or African American; Blood Pressure; Endothelium, Vascular; Female; Humans

2015
Neutrophil Gelatinase-Associated Lipocalin, a Novel Mineralocorticoid Biotarget, Mediates Vascular Profibrotic Effects of Mineralocorticoids.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 66, Issue:1

    Topics: Acute-Phase Proteins; Aldosterone; Animals; Aorta; Cardiomyopathy, Hypertrophic; Cells, Cultured; Cy

2015
[The inversion of concepts about biological role of system rennin-angiotensin II- aldosterone and functions of arterial tension as a metabolism regulator].
    Klinicheskaia laboratornaia diagnostika, 2015, Volume: 60, Issue:2

    Topics: Aldosterone; Angiotensin II; Arterial Pressure; Arteries; Chymosin; Essential Hypertension; Humans;

2015
Obstructive Sleep Apnea Using Watch-PAT 200 Is Independently Associated With an Increase in Morning Blood Pressure Surge in Never-Treated Hypertensive Patients.
    Journal of clinical hypertension (Greenwich, Conn.), 2015, Volume: 17, Issue:9

    Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Ambulat

2015
Changes in Renal Function and Oxidative Status Associated with the Hypotensive Effects of Oleanolic Acid and Related Synthetic Derivatives in Experimental Animals.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Aldosterone; Animals; Antihypertensive Agents; Antioxidants; Arginine Vasopressin; Blood Pressure; G

2015
Association of Mineralocorticoid Receptor Polymorphism I180V With Left Ventricular Hypertrophy in Resistant Hypertension.
    American journal of hypertension, 2016, Volume: 29, Issue:2

    Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hypertension; Hypertrophy, Left Ventric

2016
Effect of postural changes on aldosterone to plasma renin ratio in patients with suspected secondary hypertension.
    Annales de cardiologie et d'angeiologie, 2015, Volume: 64, Issue:3

    Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Posture; Prospecti

2015
Pharmacological profile of CS-3150, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist.
    European journal of pharmacology, 2015, Aug-15, Volume: 761

    Topics: Administration, Oral; Adrenalectomy; Aldosterone; Animals; Antihypertensive Agents; Binding, Competi

2015
Prevalence of Liddle Syndrome Among Young Hypertension Patients of Undetermined Cause in a Chinese Population.
    Journal of clinical hypertension (Greenwich, Conn.), 2015, Volume: 17, Issue:11

    Topics: Adult; Aldosterone; China; Diagnostic Errors; Essential Hypertension; Female; Humans; Hypertension;

2015
Circulating tissue inhibitor of matrix metalloproteinase-1 is associated with aldosterone-induced diastolic dysfunction.
    Journal of hypertension, 2015, Volume: 33, Issue:9

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Diastole; Echoc

2015
A renin-ssance in primary aldosteronism testing: obstacles and opportunities for screening, diagnosis, and management.
    Clinical chemistry, 2015, Volume: 61, Issue:8

    Topics: Aldosterone; Calcium Channels, L-Type; Fludrocortisone; G Protein-Coupled Inwardly-Rectifying Potass

2015
Association of Post-Saline Load Plasma Aldosterone Levels With Left Ventricular Hypertrophy in Primary Hypertension.
    American journal of hypertension, 2016, Volume: 29, Issue:3

    Topics: Adult; Aldosterone; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; I

2016
Maternal and Fetal Outcomes in Preeclampsia: Interrelations Between Insulin Resistance, Aldosterone, Metabolic Syndrome, and Polycystic Ovary Syndrome.
    Journal of clinical hypertension (Greenwich, Conn.), 2015, Volume: 17, Issue:10

    Topics: Aldosterone; Female; Humans; Hypertension; Insulin; Insulin Resistance; Metabolic Syndrome; Polycyst

2015
Screening for primary aldosteronism in an argentinian population: a multicenter prospective study.
    Archives of endocrinology and metabolism, 2015, Volume: 59, Issue:5

    Topics: Adolescent; Adult; Aged; Aldosterone; Argentina; Female; Humans; Hyperaldosteronism; Hypertension; M

2015
Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension.
    Physiological genomics, 2015, Volume: 47, Issue:10

    Topics: Aldosterone; Anesthesia; Angiotensin II; Animals; Blood Pressure; Electrolytes; Hypertension; Intest

2015
Primary Aldosteronism: Seismic Shifts.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:8

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Stress, Psychological

2015
[IMPACT OF LONG-TERM ADAPTATION TO COLD ON THE STATE OF CARDIOVASCULAR SYSTEM].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2015, Volume: 101, Issue:5

    Topics: Acclimatization; Adaptation, Physiological; Aldosterone; Angiotensin II; Animals; Arctic Regions; Ca

2015
[Primary aldosteronism].
    La Revue du praticien, 2015, Volume: 65, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Algorithms; Antihypert

2015
β-Blocker withdrawal is preferable for accurate interpretation of the aldosterone-renin ratio in chronically treated hypertension.
    Clinical endocrinology, 2016, Volume: 84, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Aged; Aldosterone; Angiotensin

2016
Clinical validation for the aldosterone-to-renin ratio and aldosterone suppression testing using simultaneous fully automated chemiluminescence immunoassays.
    Journal of hypertension, 2015, Volume: 33, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Essential Hypertension; Female; Humans;

2015
Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations.
    The New England journal of medicine, 2015, Oct-08, Volume: 373, Issue:15

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; beta Catenin; Female; Humans; Hyperaldosteroni

2015
Lipophilic Statins and Aldosterone Secretion: A Bridge Too Far?
    Circulation, 2015, Nov-10, Volume: 132, Issue:19

    Topics: Adrenal Glands; Aldosterone; Animals; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors

2015
Depressor effect of chymase inhibitor in mice with high salt-induced moderate hypertension.
    American journal of physiology. Heart and circulatory physiology, 2015, Dec-01, Volume: 309, Issue:11

    Topics: Albuminuria; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Conve

2015
Mineralocorticoid Receptor Antagonism for Cardiovascular Protection in End-Stage Renal Disease: New Data But the Controversy Continues.
    Journal of clinical hypertension (Greenwich, Conn.), 2016, Volume: 18, Issue:3

    Topics: Aldosterone; Humans; Hypertension; Kidney Failure, Chronic; Mineralocorticoid Receptor Antagonists;

2016
Blood pressure changes after catheter-based renal denervation are related to reductions in total peripheral resistance.
    Journal of hypertension, 2015, Volume: 33, Issue:12

    Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; C

2015
Normoaldosteronemic aldosterone-producing adenoma: immunochemical characterization and diagnostic implications.
    Journal of hypertension, 2015, Volume: 33, Issue:12

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Cytochrome P-45

2015
Discovery of N-[5-(6-Chloro-3-cyano-1-methyl-1H-indol-2-yl)-pyridin-3-ylmethyl]-ethanesulfonamide, a Cortisol-Sparing CYP11B2 Inhibitor that Lowers Aldosterone in Human Subjects.
    Journal of medicinal chemistry, 2015, Dec-10, Volume: 58, Issue:23

    Topics: Aldosterone; Animals; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Halogenation; Haplorhini; Humans;

2015
Sodium interference in the determination of urinary aldosterone.
    Clinical biochemistry, 2016, Volume: 49, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Reproducibility of Results; Sodi

2016
Sodium Infusion Test for Diagnosis of Primary Aldosteronism in Chinese Population.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:1

    Topics: Adult; Aged; Aldosterone; Area Under Curve; Asian People; Blood Pressure; Female; Humans; Hyperaldos

2016
Factors affecting parathyroid hormone levels in different types of primary aldosteronism.
    Clinical endocrinology, 2016, Volume: 85, Issue:2

    Topics: Adenoma; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adult; Aldosterone; Calcium; Essential Hype

2016
Inducible Knock-Down of the Mineralocorticoid Receptor in Mice Disturbs Regulation of the Renin-Angiotensin-Aldosterone System and Attenuates Heart Failure Induced by Pressure Overload.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Aldosterone; Animals; Collagen; Disease Models, Animal; Echocardiography; Electrolytes; Fibrosis; Ge

2015
Role of brain aldosterone and mineralocorticoid receptors in aldosterone-salt hypertension in rats.
    Neuroscience, 2016, Feb-09, Volume: 314

    Topics: Aldosterone; Animals; Arterial Pressure; Corticosterone; Cytochrome P-450 CYP11B2; Drinking Behavior

2016
Assessment of the Quantitative Value Usefulness of the Aldosterone-Renin Ratio (ARR) for Primary Aldosteronism (AQUARR) Study.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2016, Volume: 23, Issue:1

    Topics: Adenoma; Aldosterone; Biomarkers; Databases, Factual; Humans; Hyperaldosteronism; Hypertension; Pred

2016
Aldosterone Predicts Cardiovascular, Renal, and Metabolic Disease in the General Community: A 4-Year Follow-Up.
    Journal of the American Heart Association, 2015, Dec-23, Volume: 4, Issue:12

    Topics: Aged; Aldosterone; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Echocardiography;

2015
Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue.
    Circulation. Heart failure, 2016, Volume: 9, Issue:1

    Topics: Adipocytes, Brown; Adipocytes, White; Adipose Tissue, Brown; Adipose Tissue, White; Aldosterone; Ani

2016
Eplerenone improves carotid intima-media thickness (IMT) in patients with primary aldosteronism.
    Endocrine journal, 2016, Volume: 63, Issue:3

    Topics: Adrenalectomy; Adult; Aged; Aldosterone; Atherosclerosis; Biomarkers; Carotid Intima-Media Thickness

2016
Association Between Pituitary-Adrenal Axis Dominance Over the Renin-Angiotensin-Aldosterone System and Hypertension.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:3

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Cross-Sectional Studies; Female; Humans; Hype

2016
[Evaluation of the ratio of plasma aldosterone to rennin concentration measured by an automated chemiluminescent immunoassay in screening for primary aldosteronism].
    Zhonghua nei ke za zhi, 2016, Volume: 55, Issue:1

    Topics: Aldosterone; Area Under Curve; Case-Control Studies; Chymosin; Essential Hypertension; Humans; Hyper

2016
Prospective validation of an automated chemiluminescence-based assay of renin and aldosterone for the work-up of arterial hypertension.
    Clinical chemistry and laboratory medicine, 2016, Sep-01, Volume: 54, Issue:9

    Topics: Adult; Aldosterone; Automation; Female; Humans; Hypertension; Luminescence; Male; Middle Aged; Prosp

2016
Alteration of amiloride-sensitive salt taste nerve responses in aldosterone/NaCl-induced hypertensive rats.
    Neuroscience research, 2016, Volume: 108

    Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Body Weight; Chorda Tympani Nerve; Epithelial Sodiu

2016
Prevalence of Malignancies in Patients With Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:4

    Topics: Adult; Aged; Aldosterone; Biomarkers, Tumor; Blood Pressure; Case-Control Studies; Female; Germany;

2016
A cross-sectional study of the effects of β-blocker therapy on the interpretation of the aldosterone/renin ratio: can dosing regimen predict effect?
    Journal of hypertension, 2016, Volume: 34, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Aldosterone; Antihypertensive Agents; Cross-Sectional Studies; Di

2016
[Clinical diagnosis and treatment of adrenocortical adenoma in patients aged 60 years or above].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2016, Feb-01, Volume: 54, Issue:2

    Topics: Adrenocortical Adenoma; Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Middle Aged; Progn

2016
The Aldosterone Renin Ratio (ARR) APP as Tool to Enhance the Detection Rate of Primary Aldosteronism.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2016, Volume: 23, Issue:2

    Topics: Aldosterone; Biomarkers; Diagnosis, Computer-Assisted; Discriminant Analysis; Humans; Hyperaldostero

2016
Urinary sodium excretion predicts blood pressure response to spironolactone in patients with resistant hypertension independent of aldosterone status.
    Journal of hypertension, 2016, Volume: 34, Issue:5

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Middle Age

2016
Decrease in serum potassium levels post saline suppression test in primary aldosteronism: an under-recognised phenomenon?
    Journal of human hypertension, 2016, Volume: 30, Issue:11

    Topics: Aldosterone; Diagnostic Tests, Routine; Female; Humans; Hyperaldosteronism; Hypertension; Potassium;

2016
Common Polymorphisms at the CYP17A1 Locus Associate With Steroid Phenotype: Support for Blood Pressure Genome-Wide Association Study Signals at This Locus.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:4

    Topics: Adult; Aged; Aldosterone; Alleles; Blood Pressure; Cohort Studies; Female; Gene Expression Regulatio

2016
The story of spironolactones from 1957 to now: from sodium balance to inflammation.
    Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2016, Volume: 33 Suppl 66

    Topics: Aldosterone; History, 20th Century; History, 21st Century; Hypertension; Inflammation; Mineralocorti

2016
Activation of cardiac renin-angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder.
    Archives of physiology and biochemistry, 2017, Volume: 123, Issue:1

    Topics: Aldosterone; Animals; Ataxia Telangiectasia Mutated Proteins; Cardiovascular Diseases; Contraceptive

2017
Aldosterone-to-Renin Ratio Is Associated With Reduced 24-Hour Heart Rate Variability and QTc Prolongation in Hypertensive Patients.
    Medicine, 2016, Volume: 95, Issue:8

    Topics: Adult; Aged; Aldosterone; Austria; Autonomic Nervous System Diseases; Blood Pressure; Blood Pressure

2016
Leptin Induces Hypertension and Endothelial Dysfunction via Aldosterone-Dependent Mechanisms in Obese Female Mice.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:5

    Topics: Aldosterone; Analysis of Variance; Animals; Cardiovascular Diseases; Disease Models, Animal; Endothe

2016
Association of Circulating Renin and Aldosterone With Osteocalcin and Bone Mineral Density in African Ancestry Families.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:5

    Topics: Adult; Age Factors; Aged; Aldosterone; Anthropometry; Biomarkers; Black People; Body Mass Index; Bon

2016
Adrenal Venous Sampling in Patients With Positive Screening but Negative Confirmatory Testing for Primary Aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:5

    Topics: Adrenal Glands; Age Factors; Aged; Aldosterone; Cohort Studies; Cosyntropin; Female; Humans; Hyperal

2016
An App for the Diagnosis of Primary Aldosteronism.
    American journal of hypertension, 2016, Volume: 29, Issue:5

    Topics: Aldosterone; Arterial Pressure; Biomarkers; Computers, Handheld; Humans; Hyperaldosteronism; Hyperte

2016
SFE/SFHTA/AFCE consensus on primary aldosteronism, part 4: Subtype diagnosis.
    Annales d'endocrinologie, 2016, Volume: 77, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adult; Age Factors; Aldosterone; France; Humans; Hydrocorti

2016
Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:5

    Topics: Aldosterone; Analysis of Variance; Animals; Disease Models, Animal; Endothelium, Vascular; Hypertens

2016
A new highly sensitive and specific overnight combined screening and diagnostic test for primary aldosteronism.
    European journal of endocrinology, 2016, Volume: 175, Issue:1

    Topics: Adult; Aged; Aldosterone; Captopril; Dexamethasone; Diagnostic Tests, Routine; Female; Humans; Hyper

2016
Enhanced Soluble Serum CD40L and Serum P-Selectin Levels in Primary Aldosteronism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2016, Volume: 48, Issue:7

    Topics: Adrenocortical Adenoma; Aldosterone; Anthropometry; CD40 Ligand; Female; Humans; Hyperaldosteronism;

2016
Alterations in plasma membrane promote overexpression and increase of sodium influx through epithelial sodium channel in hypertensive platelets.
    Biochimica et biophysica acta, 2016, Volume: 1858, Issue:8

    Topics: Aged; Aldosterone; Blood Platelets; Case-Control Studies; Caveolin 1; Caveolins; Dystroglycans; Epit

2016
Letter by Campbell Regarding Article, "Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects".
    Circulation, 2016, Apr-19, Volume: 133, Issue:16

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Diabetes Mellitus; Humans; Hydroxymethylglutaryl-CoA Re

2016
Response to Letter Regarding Article, "Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects".
    Circulation, 2016, Apr-19, Volume: 133, Issue:16

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Diabetes Mellitus; Humans; Hydroxymethylglutaryl-CoA Re

2016
2016 Endocrine Society guidelines update for the diagnosis of primary aldosteronism: are the proposed aldosterone-to-renin ratio cut-off values relevant in the era of fully automated immunoassays?
    Annals of clinical biochemistry, 2016, Volume: 53, Issue:6

    Topics: Aldosterone; Automation, Laboratory; Endocrinology; Humans; Hyperaldosteronism; Hypertension; Immuno

2016
Mineralocorticoid and angiotensin II type 1 receptors in the subfornical organ mediate angiotensin II - induced hypothalamic reactive oxygen species and hypertension.
    Neuroscience, 2016, 08-04, Volume: 329

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dependovirus; Gene Knockdown Techniques; Genet

2016
In Liddle Syndrome, Epithelial Sodium Channel Is Hyperactive Mainly in the Early Part of the Aldosterone-Sensitive Distal Nephron.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:6

    Topics: Aldosterone; Animals; Disease Models, Animal; Epithelial Sodium Channels; Hypertension; Kidney Tubul

2016
SFE/SFHTA/AFCE Consensus on Primary Aldosteronism, part 2: First diagnostic steps.
    Annales d'endocrinologie, 2016, Volume: 77, Issue:3

    Topics: Age Factors; Aldosterone; Antihypertensive Agents; Blood Specimen Collection; Female; Humans; Hypera

2016
[Renin and aldosterone determinations in hypertensive patients].
    Orvosi hetilap, 2016, May-22, Volume: 157, Issue:21

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Biomarkers; Female; Humans; Hyperaldosteronism; Hyperte

2016
Causes of secondary hypertension in the young population: A monocentric study.
    Annales de cardiologie et d'angeiologie, 2016, Volume: 65, Issue:3

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Aortic Coarctation; Biomarkers; Blood Pressure Monitori

2016
Secondary hypertension in adults.
    Singapore medical journal, 2016, Volume: 57, Issue:5

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Aortic Coarctation; Blood Pressure; Glomerulo

2016
Clinical Outcomes following Percutaneous Radiofrequency Ablation of Unilateral Aldosterone-Producing Adenoma: Comparison with Adrenalectomy.
    Journal of vascular and interventional radiology : JVIR, 2016, Volume: 27, Issue:7

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Antihypertensive Agents; Bioma

2016
Angiotensin 1-7 Is a Negative Modulator of Aldosterone Secretion In Vitro and In Vivo.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 68, Issue:2

    Topics: Aldosterone; Angiotensin I; Animals; Antihypertensive Agents; Fluorescent Antibody Technique; Humans

2016
[An evaluation of plasma aldosterone-to-active-renin ratio in different postures in combination with aldosterone concentration in the diagnosis of aldosteronoma].
    Zhonghua nei ke za zhi, 2016, Volume: 55, Issue:6

    Topics: Aldosterone; Asian People; China; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension;

2016
Functional characterization of two novel germline mutations of the KCNJ5 gene in hypertensive patients without primary aldosteronism but with ACTH-dependent aldosterone hypersecretion.
    Clinical endocrinology, 2016, Volume: 85, Issue:6

    Topics: Adrenocorticotropic Hormone; Aldosterone; Cytochrome P-450 CYP11B2; Electrophysiological Phenomena;

2016
KCNK3 Variants Are Associated With Hyperaldosteronism and Hypertension.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 68, Issue:2

    Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; California; Ethnicity; Female; Genetic Pr

2016
Cardiac Structure and Function in Hyperaldosteronism.
    Circulation. Cardiovascular imaging, 2016, Volume: 9, Issue:6

    Topics: Aldosterone; Heart; Humans; Hyperaldosteronism; Hypertension

2016
SFE/SFHTA/AFCE primary aldosteronism consensus: Introduction and handbook.
    Annales d'endocrinologie, 2016, Volume: 77, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Calcium Channel Blockers; France; Humans

2016
Parathyroid hormone, aldosterone-to-renin ratio and fibroblast growth factor-23 as determinants of nocturnal blood pressure in primary hyperparathyroidism: the eplerenone in primary hyperparathyroidism trial.
    Journal of hypertension, 2016, Volume: 34, Issue:9

    Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; C

2016
Prevalence, Neurohormonal Correlates, and Prognosis of Heart Failure Stages in the Community.
    JACC. Heart failure, 2016, Volume: 4, Issue:10

    Topics: Adult; Aged; Aldosterone; C-Reactive Protein; Coronary Artery Disease; Diabetes Mellitus; Female; He

2016
ARAs to the RESCUE.
    Journal of the American Society of Hypertension : JASH, 2016, Volume: 10, Issue:3

    Topics: Aldosterone; Eplerenone; Gynecomastia; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Meta-A

2016
Dietary Sodium Restriction Increases the Risk of Misinterpreting Mild Cases of Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:11

    Topics: Adult; Aldosterone; Algorithms; Cohort Studies; Diagnostic Errors; Diet, Sodium-Restricted; Down-Reg

2016
Aldosterone-Renin Ratio and Side-Selective Renal Perfusion in Essential Hypertension.
    American journal of hypertension, 2016, 11-01, Volume: 29, Issue:11

    Topics: Aldosterone; Blood Pressure; Essential Hypertension; Humans; Hypertension; Kidney; Renin; Renin-Angi

2016
Endogenous ouabain and aldosterone are coelevated in the circulation of patients with essential hypertension.
    Journal of hypertension, 2016, Volume: 34, Issue:10

    Topics: Adult; Aldosterone; Blood Pressure; Essential Hypertension; Female; Humans; Hyperaldosteronism; Hype

2016
Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension.
    Journal of hypertension, 2016, Volume: 34, Issue:9

    Topics: Adiponectin; Adolescent; Aldosterone; Blood Pressure; Body Mass Index; C-Reactive Protein; Child; Ch

2016
Radiofrequency ablation compared with laparoscopic adrenalectomy for aldosterone-producing adenoma.
    The British journal of surgery, 2016, Volume: 103, Issue:11

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aftercare; Aged; Aged, 80 and ov

2016
On the top of ARB N/L type Ca channel blocker leads to less elevation of aldosterone.
    Bioscience reports, 2016, Volume: 36, Issue:5

    Topics: Aged; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blo

2016
Body Mass Index Predicts 24-Hour Urinary Aldosterone Levels in Patients With Resistant Hypertension.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 68, Issue:4

    Topics: Adult; Age Factors; Aged; Aldosterone; Blood Pressure Determination; Body Mass Index; Comorbidity; C

2016
Letter by Zhou and Zhou Regarding Article, "Hypertension: Renin-Angiotensin-Aldosterone System Alterations".
    Circulation research, 2016, 09-02, Volume: 119, Issue:6

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin-Angiotensin System

2016
Response by Danser and van den Meiracker to Letter by Zhou and Zhou Regarding Article, "Hypertension: Renin-Angiotensin-Aldosterone System Alterations".
    Circulation research, 2016, 09-02, Volume: 119, Issue:6

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin-Angiotensin System

2016
The Clinical Value of Salivary Aldosterone in Diagnosis and Follow-Up of Primary Aldosteronism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2016, Volume: 48, Issue:10

    Topics: Adrenalectomy; Aged; Aldosterone; Case-Control Studies; Circadian Rhythm; Eplerenone; Female; Follow

2016
Primary aldosteronism in patients with acute stroke: prevalence and diagnosis during initial hospitalization.
    BMC neurology, 2016, Sep-17, Volume: 16

    Topics: Aged; Aldosterone; Comorbidity; Female; Hospitalization; Humans; Hyperaldosteronism; Hypertension; J

2016
Cholecalciferol treatment downregulates renin-angiotensin system and improves endothelial function in essential hypertensive patients with hypovitaminosid D.
    Journal of hypertension, 2016, Volume: 34, Issue:11

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Cardiovascular Diseases; Cholecalciferol; Endoth

2016
Renal denervation attenuates aldosterone expression and associated cardiovascular pathophysiology in angiotensin II-induced hypertension.
    Oncotarget, 2016, Oct-18, Volume: 7, Issue:42

    Topics: Aldosterone; Angiotensin II; Animals; Calcitonin Gene-Related Peptide; Cell Line, Tumor; Denervation

2016
Acute Vasodilation Caused by Different Strategies of Renal Sympathetic Denervation for Right and Left Renal Arteries.
    Annals of vascular surgery, 2017, Volume: 38

    Topics: Aldosterone; Biomarkers; Blood Pressure; Catheter Ablation; Cross-Sectional Studies; Humans; Hyperte

2017
PRIMARY ALDOSTERONISM IN THE PRIMARY CARE CLINIC: RIFE OR RARE?
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2016, Volume: 22, Issue:11

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Primary Health Care; Renin

2016
Some Considerations About Primary Aldosteronism and Its Follow-Up.
    Journal of clinical hypertension (Greenwich, Conn.), 2016, Volume: 18, Issue:12

    Topics: Aldosterone; Follow-Up Studies; Humans; Hyperaldosteronism; Hypertension; Renin

2016
Increased urinary excretion of the epithelial Na channel activator prostasin in patients with primary aldosteronism.
    Journal of hypertension, 2017, Volume: 35, Issue:2

    Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Epithelial Sodium Channels; Essential Hypertension;

2017
Primary aldosteronism as a public health issue.
    The lancet. Diabetes & endocrinology, 2016, Volume: 4, Issue:12

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Public Health

2016
PREVELENCE OF PRIMARY ALDOSTERONISM IN AN URBAN HYPERTENSIVE POPULATION.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2016, Volume: 22, Issue:11

    Topics: Adult; Aged; Aldosterone; Comorbidity; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middl

2016
Liddle syndrome: clinical and genetic profiles.
    Journal of clinical hypertension (Greenwich, Conn.), 2017, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Aldosterone; Alleles; Child; China; Creatinine; Epithelial Sodium Channel Blocker

2017
Whole-exome sequencing reveals an inherited R566X mutation of the epithelial sodium channel β-subunit in a case of early-onset phenotype of Liddle syndrome.
    Cold Spring Harbor molecular case studies, 2016, Volume: 2, Issue:6

    Topics: Adult; Aldosterone; Alleles; Amiloride; Child, Preschool; Epithelial Sodium Channels; Exome; Exome S

2016
High-sensitive C-reactive protein in primary aldosteronism.
    Journal of hypertension, 2017, Volume: 35, Issue:1

    Topics: Aldosterone; C-Reactive Protein; Humans; Hyperaldosteronism; Hypertension

2017
Role of adrenocorticotropic hormone in essential hypertension and primary aldosteronism.
    Journal of clinical hypertension (Greenwich, Conn.), 2017, Volume: 19, Issue:3

    Topics: Adenoma; Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Essential Hypertension; Humans; H

2017
Plasma adrenocorticotropic hormone but not aldosterone is correlated with blood pressure in patients with aldosterone-producing adenomas.
    Journal of clinical hypertension (Greenwich, Conn.), 2017, Volume: 19, Issue:3

    Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Blood Pressure; Essential Hypertensi

2017
High Frequency of Variants of Candidate Genes in Black Africans with Low Renin-Resistant Hypertension.
    American journal of hypertension, 2017, 05-01, Volume: 30, Issue:5

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Black People; Blood Pressure; Cytochrome P-450

2017
Novel Approach to Establishing an Aldosterone: Renin Ratio Cutoff for Primary Aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 69, Issue:3

    Topics: Alberta; Aldosterone; Biomarkers; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Age

2017
Positive association between KCNJ5 rs2604204 (A/C) polymorphism and plasma aldosterone levels, but also plasma renin and angiotensin I and II levels, in newly diagnosed hypertensive Chinese: a case-control study.
    Journal of human hypertension, 2017, Volume: 31, Issue:7

    Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure Monitoring, Ambulatory; Case-Contr

2017
Assessment of the Aldosteronona resolution score as a predictive resolution score of hypertension after adrenalectomy for aldosteronoma in French patients.
    Langenbeck's archives of surgery, 2017, Volume: 402, Issue:2

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aged, 80 and over; Aldoste

2017
Plasma aldosterone level within the normal range is less associated with cardiovascular and cerebrovascular risk in primary aldosteronism.
    Journal of hypertension, 2017, Volume: 35, Issue:5

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Cardiovascular Diseases; Cross-Sectional Studies; Essentia

2017
Changes in the expression of α
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 88

    Topics: Adult; Aldosterone; Animals; Blood Pressure; Enzyme Inhibitors; Female; Homocysteine; Humans; Hypert

2017
Early treatment with losartan effectively ameliorates hypertension and improves vascular remodeling and function in a prehypertensive rat model.
    Life sciences, 2017, Mar-15, Volume: 173

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Expression Regula

2017
Clinical outcomes following unilateral adrenalectomy in patients with primary aldosteronism.
    QJM : monthly journal of the Association of Physicians, 2017, May-01, Volume: 110, Issue:5

    Topics: Adrenalectomy; Adult; Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Blood Pressure;

2017
Increased Aldosterone Release During Head-Up Tilt in Early Primary Hypertension.
    American journal of hypertension, 2017, May-01, Volume: 30, Issue:5

    Topics: Adult; Age Factors; Aldosterone; Angiotensin II; Biomarkers; Blood Pressure; Case-Control Studies; H

2017
The importance of genetic counseling and genetic screening: a case report of a 16-year-old boy with resistant hypertension and severe hypokalemia.
    Journal of the American Society of Hypertension : JASH, 2017, Volume: 11, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; 46, XX Disorders of Sex Development; Adolescent; Adrenal Glan

2017
Serum uric acid is not independently associated with plasma renin activity and plasma aldosterone in hypertensive adults.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2017, Volume: 27, Issue:4

    Topics: Adiposity; Adult; Age Factors; Aldosterone; Biomarkers; Blood Pressure; Chi-Square Distribution; Cro

2017
Primary Aldosteronism or Not Primary Aldosteronism: Is This Now the Question in Normotension?
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 69, Issue:5

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension

2017
A Late Diagnosis of Primary Aldosteronism.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2017, Volume: 24, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Antihypertensiv

2017
Characterization of resistant hypertension: association between resistant hypertension, aldosterone, and persistent intravascular volume expansion.
    Archives of internal medicine, 2008, Jun-09, Volume: 168, Issue:11

    Topics: Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Case-Control Studies; Drug Resistan

2008
Increased carotid intima-media thickness in hypertensive patients with a high aldosterone/plasma renin activity ratio and elevated aldosterone plasma concentration.
    Journal of hypertension, 2008, Volume: 26, Issue:7

    Topics: Aldosterone; Carotid Arteries; Humans; Hypertension; Renin; Tunica Intima; Tunica Media; Ultrasonogr

2008
Plasma aldosterone and its relationships with left ventricular mass in essential hypertensive patients with the metabolic syndrome.
    American journal of hypertension, 2008, Volume: 21, Issue:9

    Topics: Adult; Aldosterone; Blood Pressure; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Lef

2008
Primary hyperaldosteronism due to adrenal microadenoma: a curable cause of refractory hypertension.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2008, Volume: 9, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Antihypertensive Agents; Blood Pressu

2008
Menopause not aldosterone-to-renin ratio predicts blood pressure response to a mineralocorticoid receptor antagonist in primary care hypertensive patients.
    American journal of hypertension, 2008, Volume: 21, Issue:9

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aldosterone; Blood Pressure; Canrenoic Acid; Female; Huma

2008
Response to genetic manipulations of liver angiotensinogen in the physiological range.
    Journal of human genetics, 2008, Volume: 53, Issue:9

    Topics: Aldosterone; Angiotensinogen; Animals; Gene Dosage; Genetic Engineering; Hypertension; Liver; Male;

2008
Exaggerated blood pressure response to exercise is associated with augmented rise of angiotensin II during exercise.
    Journal of the American College of Cardiology, 2008, Jul-22, Volume: 52, Issue:4

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Bicycling; Blood Pressure; Case-Control Studies; Catechola

2008
Effects of aldosterone on the heart: beyond systemic hemodynamics?
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Heart; Humans; Hypertension; Hypertrophy, Left Ventricular

2008
Inappropriate left ventricular mass in patients with primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:3

    Topics: Adaptation, Physiological; Adult; Aged; Aldosterone; Echocardiography; Female; Humans; Hyperaldoster

2008
A patient with a juxtaglomerular cell tumor with histological vascular invasion.
    Nature clinical practice. Nephrology, 2008, Volume: 4, Issue:8

    Topics: Aldosterone; Blood Vessels; Female; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney Neoplasm

2008
Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Volume: 22, Issue:11

    Topics: Adiposity; Aldosterone; Angiotensins; Animals; Blood Glucose; Blood Pressure; Cell Line; Diet; Dieta

2008
Blood pressure outcome of adrenalectomy in patients with primary hyperaldosteronism with or without unilateral adenoma.
    Journal of hypertension, 2008, Volume: 26, Issue:9

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Female; Follow-

2008
Effect of weight loss through laparoscopic gastric banding on blood pressure, plasma renin activity and aldosterone levels in morbid obesity.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2009, Volume: 19, Issue:2

    Topics: Adult; Aldosterone; Bariatric Surgery; Blood Glucose; Blood Pressure; Down-Regulation; Female; Human

2009
[Possible pathogenetic role of 11 beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) gene polymorphisms in arterial hypertension].
    Revista medica de Chile, 2008, Volume: 136, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adrenocorticotropic Hormone; Adult; Aldosterone; Case-C

2008
Polymorphism of the aldosterone synthase gene is not associated with progression of diabetic nephropathy, but associated with hypertension in type 2 diabetic patients.
    Nephrology (Carlton, Vic.), 2008, Volume: 13, Issue:6

    Topics: Adult; Aged; Aldosterone; Cytochrome P-450 CYP11B2; Diabetes Mellitus, Type 2; Diabetic Nephropathie

2008
Screening for primary aldosteronism in a cohort of Brazilian patients with resistant hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2008, Volume: 10, Issue:8

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aged; Aldosterone; Brazil; Cross-Sectional Studies

2008
[Primary hyperaldosteronism in hypertension].
    Revue medicale suisse, 2008, Sep-10, Volume: 4, Issue:170

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

2008
Primary aldosteronism in newly diagnosed hypertensive patients.
    Journal of hypertension, 2008, Volume: 26, Issue:11

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Predictive Value of Tests; Reference Values;

2008
The cutoff value of aldosterone-to-renin ratio for the diagnosis of primary aldosteronism in patients taking antihypertensive medicine.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2008, Volume: 30, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Aged; Aldosterone; Antihypertensi

2008
[Role of antialdosteronics in the treatment of refractory hypertension].
    Medicina clinica, 2008, Oct-04, Volume: 131, Issue:11

    Topics: Aldosterone; Clinical Trials as Topic; Diuretics; Drug Resistance; Humans; Hypertension; Mineralocor

2008
The blood pressure variability, arterial elasticity and humoral factors in subjects with family history of hypertension.
    The Medical journal of Malaysia, 2008, Volume: 63, Issue:1

    Topics: Adult; Aldosterone; Arteries; Blood Pressure; Catecholamines; Elasticity; Female; Humans; Hypertensi

2008
Relationship of plasma renin with a prothrombotic state in hypertension: relevance for organ damage.
    American journal of hypertension, 2008, Volume: 21, Issue:12

    Topics: Adult; Aldosterone; Algorithms; Analysis of Variance; Biomarkers; Cerebrovascular Disorders; Cross-S

2008
Hypertension-induced renal fibrosis and spironolactone response vary by rat strain and mineralocorticoid receptor gene expression.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2008, Volume: 9, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Collagen Type I; Fibrosis; Gene Expression Regula

2008
Collectrin is involved in the development of salt-sensitive hypertension by facilitating the membrane trafficking of apical membrane proteins via interaction with soluble N-ethylmaleiamide-sensitive factor attachment protein receptor complex.
    Circulation, 2008, Nov-18, Volume: 118, Issue:21

    Topics: Aldosterone; Animals; Aquaporin 2; Blood Pressure; Cell Line; Collectins; Epithelial Sodium Channels

2008
Angiotensinogen gene haplotypes in hypertension.
    Journal of hypertension, 2008, Volume: 26, Issue:12

    Topics: Aldosterone; Alleles; Angiotensinogen; Haplotypes; Humans; Hypertension; Polymorphism, Single Nucleo

2008
Actions of aldosterone in the cardiovascular system: the good, the bad, and the ugly?
    Pflugers Archiv : European journal of physiology, 2009, Volume: 458, Issue:2

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Cardiovascular System; ErbB Receptors; Homeostasis; Hyp

2009
"Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:1

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim

2009
Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study.
    Circulation, 2009, Jan-06, Volume: 119, Issue:1

    Topics: Aldosterone; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; C-Reactive Protein; Cross-Sectio

2009
Mechanisms in the PVN mediating local and central sodium-induced hypertension in Wistar rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:3

    Topics: Aldosterone; Amiloride; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic

2009
Mineralocorticoid receptor antagonism attenuates vascular apoptosis and injury via rescuing protein kinase B activation.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:2

    Topics: Aldosterone; Animals; Aorta, Thoracic; Apoptosis; bcl-Associated Death Protein; Blood Pressure; Cyto

2009
Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt-induced hypertension in Dahl salt-sensitive rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:4

    Topics: Aldosterone; Animals; Blood Pressure; Corticosterone; Cytochrome P-450 CYP11B2; Disease Models, Anim

2009
Expression of NAD(P)H oxidase subunits and their contribution to cardiovascular damage in aldosterone/salt-induced hypertensive rat.
    Journal of Korean medical science, 2008, Volume: 23, Issue:6

    Topics: Acetophenones; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agen

2008
Endocrine rhythms and expression of selected genes in the brain, stellate ganglia, and adrenals of hypertensive TGR rats.
    Annals of the New York Academy of Sciences, 2008, Volume: 1148

    Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Brain; Circadian Rhythm; Corticosterone; Dopam

2008
Small tumor size as favorable prognostic factor after adrenalectomy in Conn's adenoma.
    European journal of endocrinology, 2009, Volume: 160, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aged; Aldosterone; Blood Pressure;

2009
Aldosterone and Cardiovascular Disease. Foreword.
    Current problems in cardiology, 2009, Volume: 34, Issue:2

    Topics: Adrenalectomy; Aldosterone; Animals; Antihypertensive Agents; Cardiovascular Agents; Cardiovascular

2009
Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension.
    Journal of hypertension, 2009, Volume: 27, Issue:1

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured; Esters; Gabexate; Gu

2009
Aldosterone and alterations of hypertension-related vascular function in African Americans.
    American journal of hypertension, 2009, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Anthropometry; Black or African American; Cardiac Output; Catecholam

2009
Aldosterone levels and stroke incidence in essential hypertensive patients.
    International journal of cardiology, 2010, Sep-24, Volume: 144, Issue:1

    Topics: Aldosterone; Blood Pressure; Cross-Sectional Studies; Female; Follow-Up Studies; Greece; Humans; Hyp

2010
Primary hyperaldosteronism in a domestic ferret with an adrenocortical adenoma.
    Journal of the American Veterinary Medical Association, 2008, Oct-15, Volume: 233, Issue:8

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Animals; Fatal Outcome; Female; Ferre

2008
[Evaluation of selected endocrine parameters in smoking patients with arterial hypertension].
    Przeglad lekarski, 2008, Volume: 65, Issue:10

    Topics: Aldosterone; Female; Humans; Hypertension; Insulin; Male; Middle Aged; Smoking

2008
Primary aldosteronism with aldosterone-producing adenoma consisting of pure zona glomerulosa-type cells in a pregnant woman.
    Endocrine pathology, 2009,Spring, Volume: 20, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Estrogen Recept

2009
Prevalence of primary hyperaldosteronism in a systemic arterial hypertension league.
    Arquivos brasileiros de cardiologia, 2009, Volume: 92, Issue:1

    Topics: Adrenal Glands; Aldosterone; Antihypertensive Agents; Fasting; Female; Humans; Hyperaldosteronism; H

2009
Aldosterone and metabolic dysfunction: an unresolved issue.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:4

    Topics: Aldosterone; Animals; Dyslipidemias; Humans; Hyperaldosteronism; Hypertension; Hypokalemia

2009
Trilostane, FAD286, and the role of aldosterone in the central regulation of blood pressure: focus on "Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt-induced hypertension in Dahl salt-sensitive rats".
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Blood Pressure; Corticosterone; Cytochrome P-

2009
Left ventricular hypertrophy and geometry in hypertensive patients with chronic kidney disease.
    Journal of hypertension, 2009, Volume: 27, Issue:3

    Topics: Aged; Aldosterone; Blood Pressure Determination; Case-Control Studies; Catecholamines; Chronic Disea

2009
Blood pressure outcome of adrenalectomy in patients with primary hyperaldosteronism with or without unilateral adenoma.
    Journal of hypertension, 2009, Volume: 27, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Blood Pressure;

2009
T allele of -344 C/T polymorphism in aldosterone synthase gene is not associated with resistant hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:2

    Topics: Adult; Aldosterone; Alleles; Blood Pressure; Carotid Arteries; Cytochrome P-450 CYP11B2; Drug Resist

2009
Sex differences and central protective effect of 17beta-estradiol in the development of aldosterone/NaCl-induced hypertension.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Administration, Oral; Aldosterone; Animals; Blood Pressure; Body Weight; Brain; Disease Models, Anim

2009
Medical management of primary aldosteronism.
    Annales d'endocrinologie, 2009, Volume: 70, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

2009
Hypertension, insulin resistance, and aldosterone: sex-specific relationships.
    Journal of clinical hypertension (Greenwich, Conn.), 2009, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aldosterone; Anthropometry; Black or African American; Blood Glucose

2009
Aldosterone blockade by Spironolactone improves the hypertensive vascular hypertrophy and remodeling in angiotensin II overproducing transgenic mice.
    Atherosclerosis, 2009, Volume: 206, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Female; Hyperplasia; Hypertension; Hypertrophy; Male; Mice; Mi

2009
Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats.
    Journal of hypertension, 2009, Volume: 27, Issue:3

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cytoc

2009
Renal functional, not morphological, abnormalities account for salt sensitivity in Dahl rats.
    Journal of hypertension, 2009, Volume: 27, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cyclic GMP; Diastole; Dose-Response Relationsh

2009
Swimming prevents vulnerable atherosclerotic plaque development in hypertensive 2-kidney, 1-clip mice by modulating angiotensin II type 1 receptor expression independently from hemodynamic changes.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:5

    Topics: Aldosterone; Animals; Apolipoproteins E; Atherosclerosis; Blood Pressure; Cholesterol; Citrate (si)-

2009
Endothelial dysfunction is related to aldosterone excess and raised blood pressure.
    Endocrine journal, 2009, Volume: 56, Issue:4

    Topics: Aged; Aldosterone; Endothelium, Vascular; Female; Humans; Hyperaldosteronism; Hypertension; Male; Mi

2009
Programming of hypertension: associations of plasma aldosterone in adult men and women with birthweight, cortisol, and blood pressure.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:6

    Topics: Adrenocorticotropic Hormone; Age Factors; Aged; Aldosterone; Analysis of Variance; Birth Weight; Blo

2009
Factors determining cardiovascular and renal outcomes after adrenalectomy in patients with aldosterone-producing adrenal adenoma.
    The Tohoku journal of experimental medicine, 2009, Volume: 218, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Cardiovas

2009
Long-term effects of surgical correction of adrenal hyperplasia and adenoma causing primary aldosteronism.
    Langenbeck's archives of surgery, 2010, Volume: 395, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Analysis of Variance;

2010
Hyperaldosteronism in an adolescent with Gardner's syndrome.
    Journal of pediatric surgery, 2009, Volume: 44, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Female; Fibromatosis, Aggr

2009
Aberrant ENaC activation in Dahl salt-sensitive rats.
    Journal of hypertension, 2009, Volume: 27, Issue:8

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Epithelial Sodium Channels; Hypertension; Kidney;

2009
Aldosterone-producing adrenal cortical adenoma with oncocytic change and cytoplasmic eosinophilic globular inclusions.
    Endocrine pathology, 2009,Fall, Volume: 20, Issue:3

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aged; Aldosterone; Antihypertensive Agents; Female

2009
Aldosterone, a vasculotoxic agent--novel functions for an old hormone.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:8

    Topics: Aldosterone; Blood Pressure; Blood Vessels; Humans; Hypertension; Receptors, Mineralocorticoid

2009
Metabolic syndrome in primary aldosteronism and essential hypertension: relationship to adiponectin gene variants.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2010, Volume: 20, Issue:2

    Topics: Adiponectin; Aldosterone; Biomarkers; Blood Glucose; Chi-Square Distribution; Cross-Sectional Studie

2010
Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:3

    Topics: Adenomatous Polyposis Coli Protein; Aldosterone; Animals; Blood Pressure; Blood Volume; Body Weight;

2009
Aldosterone in clinical nephrology--old hormone, new questions.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:8

    Topics: Aldosterone; Eplerenone; Humans; Hypertension; Kidney Diseases; Mineralocorticoid Receptor Antagonis

2009
Elevated aldosterone levels in patients with androgenetic alopecia.
    The British journal of dermatology, 2009, Volume: 161, Issue:5

    Topics: Adult; Aldosterone; Alopecia; Case-Control Studies; Humans; Hypertension; Male; Middle Aged; Pilot P

2009
Adrenal venous sampling for primary aldosteronism and clinical outcomes after unilateral adrenalectomy: a single-center experience.
    Journal of clinical hypertension (Greenwich, Conn.), 2009, Volume: 11, Issue:6

    Topics: Adrenalectomy; Adult; Aldosterone; Blood Pressure; Creatinine; Female; Humans; Hyperaldosteronism; H

2009
Going with the Wnt? Focus on "Hyperaldosteronism, hypervolemia, and increased blood pressure in mice expressing defective APC".
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:3

    Topics: Adenomatous Polyposis Coli Protein; Aldosterone; Animals; Blood Pressure; Blood Volume; Glomerular F

2009
Sodium chloride and aldosterone: harbingers of hypertension-related cardiovascular disease.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Cardiovascular Diseases; Echocardiography; Humans; Hypertensio

2009
Independent relations of left ventricular structure with the 24-hour urinary excretion of sodium and aldosterone.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Echocardiography; Female; H

2009
Primary aldosteronism can alter peripheral levels of transforming growth factor beta and tumor necrosis factor alpha.
    Journal of endocrinological investigation, 2009, Volume: 32, Issue:9

    Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Inter

2009
Atrial fibrillation in primary aldosteronism.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2009, Volume: 10, Issue:4

    Topics: Adult; Aldosterone; Atrial Fibrillation; Female; Humans; Hyperaldosteronism; Hypertension; Hypertrop

2009
Effects of fixed-dose isosorbide dinitrate/hydralazine on diastolic function and exercise capacity in hypertension-induced diastolic heart failure.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:3

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Cytokines; Diastole; Drug Therapy,

2009
Association of kidney function with residual hypertension after treatment of aldosterone-producing adenoma.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 54, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Creatinine; Fe

2009
[Normokalaemic primary aldosteronism due to an aldosterone-producing adrenal adenoma--Case 06/2009].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:31-32

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Diagnosis, Diff

2009
Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:3

    Topics: Aldosterone; Animals; Antibodies, Monoclonal; Blood Pressure; Enzyme Inhibitors; Gene Expression; Hy

2009
[Neurohumoral regulation of blood pressure in rheumatic patients].
    Terapevticheskii arkhiv, 2009, Volume: 81, Issue:6

    Topics: Aldosterone; Blood Pressure; Catecholamines; Endothelins; Epinephrine; Humans; Hypertension; Kidney;

2009
[Endocrine hypertension].
    Ugeskrift for laeger, 2009, Jun-15, Volume: 171, Issue:25

    Topics: Adrenal Gland Neoplasms; Aldosterone; Cushing Syndrome; Humans; Hyperaldosteronism; Hypertension; Hy

2009
Update in primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:10

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Amiloride; Antihypertensive Agents; Chromos

2009
Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:5

    Topics: Administration, Oral; Aldosterone; Animals; Cardiomegaly; Collagen Type I; Cytochrome P-450 CYP1A1;

2009
Aldosterone contributes to blood pressure variance and to likelihood of hypertension in normal-weight and overweight African Americans.
    American journal of hypertension, 2009, Volume: 22, Issue:12

    Topics: Adult; Aldosterone; Black or African American; Blood Pressure; Body Mass Index; Cross-Sectional Stud

2009
Dietary salt restriction activates mineralocorticoid receptor signaling in volume-overloaded heart failure.
    European journal of pharmacology, 2009, Nov-25, Volume: 623, Issue:1-3

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Body Weight; Cell Size; Contraindications; Diet, So

2009
The dual role of the kidney in primary aldosteronism: key determinant in rescue from volume expansion and persistence of hypertension.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 54, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hyperten

2009
CYP11B2 gene haplotypes independently and in concurrence with aldosterone and aldosterone to renin ratio increase the risk of hypertension.
    Clinical biochemistry, 2010, Volume: 43, Issue:1-2

    Topics: Adult; Aged; Aldosterone; Cytochrome P-450 CYP11B2; Genetic Predisposition to Disease; Haplotypes; H

2010
[Correlations between heart rate variability, renin activity and plasma aldosteron concentration in chronic glomerulonephritis with intact function of the kidneys].
    Terapevticheskii arkhiv, 2009, Volume: 81, Issue:8

    Topics: Adult; Aldosterone; Autonomic Nervous System; Cardiovascular System; Chronic Disease; Glomerulonephr

2009
The role of aldosterone in mediating the dependence of angiotensin hypertension on IL-6.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:6

    Topics: Aldosterone; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; D

2009
Familial and phenotypic associations of the aldosterone Renin ratio.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:11

    Topics: Adult; Aldosterone; Blood Pressure; Body Mass Index; Circadian Rhythm; Family; Female; Genotype; Hum

2009
Aldosterone synthesis in the brain contributes to Dahl salt-sensitive rat hypertension.
    Experimental physiology, 2010, Volume: 95, Issue:1

    Topics: Aldosterone; Animals; Brain; Cytochrome P-450 CYP11B2; Female; Hypertension; Male; Rats; Rats, Inbre

2010
Clinical effects of eplerenone, a selective aldosterone blocker, in Japanese patients with essential hypertension.
    Journal of human hypertension, 2010, Volume: 24, Issue:6

    Topics: Aged; Albuminuria; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; A

2010
Some considerations about evolution of idiopathic primary aldosteronism.
    Journal of endocrinological investigation, 2009, Volume: 32, Issue:7

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Refer

2009
Hypovolaemia-induced metabolic dysfunction, mediated in part by aldosterone and angiotensin.
    Journal of hypertension, 2009, Volume: 27, Issue:10

    Topics: Aldosterone; Angiotensins; Humans; Hypertension; Hypovolemia; Metabolic Syndrome; Renin-Angiotensin

2009
Gender differences in angiotensin II and aldosterone secretion in patients with pressure overloaded systemic right ventricles are similar to those observed in systemic arterial hypertension.
    International journal of cardiology, 2011, Mar-17, Volume: 147, Issue:3

    Topics: Adolescent; Aldosterone; Angiotensin II; Biomarkers; Blood Pressure; Female; Humans; Hypertension; I

2011
Hypertension and aldosterone levels in women with early-onset androgenetic alopecia.
    The British journal of dermatology, 2010, Volume: 162, Issue:4

    Topics: Adult; Age Factors; Aldosterone; Alopecia; Biomarkers; Blood Pressure; Case-Control Studies; Female;

2010
Nonalcoholic fatty liver disease in primary aldosteronism: a pilot study.
    American journal of hypertension, 2010, Volume: 23, Issue:1

    Topics: Adult; Aldosterone; Fatty Liver; Female; Homeostasis; Humans; Hyperaldosteronism; Hypertension; Hypo

2010
Aldosterone and hypertension in African Americans.
    American journal of hypertension, 2009, Volume: 22, Issue:12

    Topics: Aldosterone; Black or African American; Humans; Hypertension; Renin

2009
Inappropriately high circulating and intrarenal angiotensin II levels during dietary salt loading exacerbate hypertension in Cyp1a1-Ren-2 transgenic rats.
    Journal of hypertension, 2010, Volume: 28, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Creatinine; Cytochrome P-450 CYP1A1; Hypertens

2010
Within-patient reproducibility of the aldosterone: renin ratio in primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldoste

2010
Commentary.
    Clinical chemistry, 2009, Volume: 55, Issue:12

    Topics: Aldosterone; Dietary Supplements; Female; Glycyrrhiza; Glycyrrhizic Acid; Humans; Hypertension; Hypo

2009
Too much of a good thing: a woman with hypertension and hypokalemia.
    Clinical chemistry, 2009, Volume: 55, Issue:12

    Topics: Aldosterone; Chronic Disease; Dietary Supplements; Female; Glycyrrhiza; Glycyrrhizic Acid; Humans; H

2009
Commentary.
    Clinical chemistry, 2009, Volume: 55, Issue:12

    Topics: Aldosterone; Dietary Supplements; Female; Glycyrrhiza; Glycyrrhizic Acid; Humans; Hypertension; Hypo

2009
Choice of diuretic therapy and reconsideration for aldosterone receptors blockers.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Aldosterone; Blood Pressure; Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Humans; Hy

2010
Effects of female sex hormones and contraceptive pill on the diagnostic work-up for primary aldosteronism.
    Journal of hypertension, 2010, Volume: 28, Issue:1

    Topics: Aldosterone; Comorbidity; Contraceptives, Oral; Estradiol; Female; Humans; Hyperaldosteronism; Hyper

2010
Spironolactone for all hypertensive patients?
    Journal of hypertension, 2010, Volume: 28, Issue:1

    Topics: Aldosterone; Diuretics; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hypertension; Practic

2010
Vasculoprotective effect of cilostazol in aldosterone-induced hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:3

    Topics: Aldosterone; Animals; Aorta; Atherosclerosis; Blood Pressure; Chemokine CCL2; Cilostazol; Disease Mo

2010
Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6.
    Nature medicine, 2010, Volume: 16, Issue:1

    Topics: Aldosterone; Animals; Circadian Rhythm; Cryptochromes; Gene Expression Regulation; Humans; Hypertens

2010
Common genetic variations of the renin-angiotensin-aldosterone system and response to acute angiotensin I-converting enzyme inhibition in essential hypertension.
    Journal of hypertension, 2010, Volume: 28, Issue:4

    Topics: Adult; Aldosterone; Alleles; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Antihyperten

2010
Hypertension finds a new rhythm.
    Nature medicine, 2010, Volume: 16, Issue:1

    Topics: Aldosterone; Animals; Circadian Rhythm; Cryptochromes; Hypertension; Mice; Progesterone Reductase; S

2010
Plasma aldosterone and glomerular filtration in hypertensive patients with preserved renal function.
    Revista espanola de cardiologia, 2010, Volume: 63, Issue:1

    Topics: Aldosterone; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Pr

2010
Improved quality of life, blood pressure, and biochemical status following laparoscopic adrenalectomy for unilateral primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:3

    Topics: Adrenalectomy; Adult; Aged; Aldosterone; Blood Pressure; Female; Health Status; Humans; Hyperaldoste

2010
Are plasma renin activity and aldosterone levels useful as a screening test to differentiate between unilateral and bilateral renal artery stenosis in hypertensive patients?
    Journal of hypertension, 2010, Volume: 28, Issue:3

    Topics: Adult; Aldosterone; Angioplasty, Balloon; Female; Humans; Hypertension; Male; Middle Aged; Renal Art

2010
[Clinical characteristics of five elderly patients with severe hypokalemia induced by glycyrrhizin derivatives].
    Nihon Jinzo Gakkai shi, 2010, Volume: 52, Issue:1

    Topics: Aged; Aged, 80 and over; Aldosterone; Alkalosis; Anti-Inflammatory Agents; Drugs, Chinese Herbal; Fe

2010
Adipokines and cardiometabolic profile in primary hyperaldosteronism.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:5

    Topics: Adenoma; Adiponectin; Adult; Aged; Aldosterone; Biomarkers; Blood Glucose; Blood Pressure; C-Reactiv

2010
[Effect of electroacupuncture of different acupoints on blood pressure, plasma angiotensin II, aldosterone and atrial natriuretic peptide in spontaneous hypertension rats].
    Zhen ci yan jiu = Acupuncture research, 2009, Volume: 34, Issue:6

    Topics: Acupuncture Points; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure;

2009
Salivary aldosterone as a diagnostic aid in primary aldosteronism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2010, Volume: 42, Issue:6

    Topics: Adenoma; Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aged; Aged, 80 and over; Aldos

2010
Pathogenesis of hypertension: interactions among sodium, potassium, and aldosterone.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2010, Volume: 55, Issue:6

    Topics: Aldosterone; Elasticity; Endothelium, Vascular; Humans; Hypertension; Male; Middle Aged; Nitric Oxid

2010
Plasma renin activity and aldosterone concentration are not altered by the novel calcium channel antagonist, azelnidipine, in hypertensive patients.
    Internal medicine (Tokyo, Japan), 2010, Volume: 49, Issue:7

    Topics: Aged; Aged, 80 and over; Aldosterone; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Bloc

2010
RGS2 expression and aldosterone: renin ratio modulate response to drug therapy in hypertensive patients.
    Journal of hypertension, 2010, Volume: 28, Issue:5

    Topics: Adolescent; Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Cohort Studies; Drug

2010
Current Opinion in Endocrinology, Diabetes & Obesity. Editorial overview.
    Current opinion in endocrinology, diabetes, and obesity, 2010, Volume: 17, Issue:3

    Topics: Adrenal Cortex; Adrenal Insufficiency; Aldosterone; Humans; Hydrocortisone; Hyperaldosteronism; Hype

2010
Aldosterone/renin ratio determines peripheral and central blood pressure values over a broad range.
    Journal of the American College of Cardiology, 2010, May-11, Volume: 55, Issue:19

    Topics: Aldosterone; Biomarkers; Cohort Studies; Coronary Angiography; Cross-Sectional Studies; Female; Huma

2010
New insight into the role of aldosterone/renin ratio in elevated peripheral and central blood pressure.
    Journal of the American College of Cardiology, 2010, May-11, Volume: 55, Issue:19

    Topics: Aldosterone; Biomarkers; Humans; Hyperaldosteronism; Hypertension; Renin; Renin-Angiotensin System

2010
[A 58-year-old hypertensive patient with primary hyperaldosteronism and renal artery stenosis].
    Medizinische Klinik (Munich, Germany : 1983), 2010, Volume: 105, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiography; Angioplasty, Balloon; Di

2010
Difficult-to-control hypertension due to bilateral aldosterone-producing adrenocortical microadenomas associated with a cortisol-producing adrenal macroadenoma.
    Journal of human hypertension, 2011, Volume: 25, Issue:2

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Cushin

2011
Familial adenomatous polyposis and hypertension.
    Lancet (London, England), 2010, May-15, Volume: 375, Issue:9727

    Topics: Adenomatous Polyposis Coli; Adrenal Glands; Adult; Aldosterone; Humans; Hyperaldosteronism; Hyperpla

2010
Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2010, Volume: 43, Issue:5

    Topics: Aldosterone; Animals; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Felodipine;

2010
Mechanisms underlying off-target effects of the cholesteryl ester transfer protein inhibitor torcetrapib involve L-type calcium channels.
    Journal of hypertension, 2010, Volume: 28, Issue:8

    Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Aldosterone; Amides; Angiotensin II; Animals; Anticholester

2010
Delayed diagnosis of primary hyperaldosteronism.
    BMJ (Clinical research ed.), 2010, May-25, Volume: 340

    Topics: Adult; Aldosterone; Calcium Channel Blockers; Delayed Diagnosis; Dihydropyridines; Drug Resistance;

2010
Long-term effects of telmisartan on blood pressure, the renin-angiotensin-aldosterone system, and lipids in hypertensive patients.
    Heart and vessels, 2010, Volume: 25, Issue:3

    Topics: Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihyper

2010
Indicators of mineralocorticoid excess in the evaluation of primary aldosteronism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:8

    Topics: Adult; Aged; Aldosterone; Biomarkers; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertensi

2010
The prevalence of metabolic syndrome and its components in two main types of primary aldosteronism.
    Journal of human hypertension, 2010, Volume: 24, Issue:10

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Biomarkers; Blood Pressure; Body Mass Index; C

2010
Predictors of resolution of hypertension after adrenalectomy in patients with aldosterone-producing adenoma.
    Journal of Korean medical science, 2010, Volume: 25, Issue:7

    Topics: Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hyper

2010
Licorice-induced hypertension and common variants of genes regulating renal sodium reabsorption.
    Annals of medicine, 2010, Volume: 42, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adolescent; Adult; Aldosterone; Epithelial Sodium Chann

2010
[The accuracy of combining aldosterone to renin ratio and low renin level in diagnosing primary aldosteronism].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2010, Volume: 41, Issue:3

    Topics: Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin; ROC C

2010
Metabolic syndrome and primary aldosteronism: time for reappraisal?
    Journal of human hypertension, 2010, Volume: 24, Issue:10

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Biomarkers; Blood Pressure; Body Mass Index; Humans;

2010
Association of HSD3B1 and HSD3B2 gene polymorphisms with essential hypertension, aldosterone level, and left ventricular structure.
    European journal of endocrinology, 2010, Volume: 163, Issue:4

    Topics: Adult; Aldosterone; Case-Control Studies; Echocardiography; Female; Genotype; Haplotypes; Humans; Hy

2010
Aldosterone inhibition and cardiovascular protection: more important than it once appeared.
    Cardiovascular drugs and therapy, 2010, Volume: 24, Issue:4

    Topics: Aldosterone; Atherosclerosis; Blood Vessels; Cardiomegaly; Cardiotonic Agents; Endothelium; Heart Fa

2010
The aldosterone-renin ratio based on the plasma renin activity and the direct renin assay for diagnosing aldosterone-producing adenoma.
    Journal of hypertension, 2010, Volume: 28, Issue:9

    Topics: Adenoma; Adult; Aged; Aldosterone; Blood Chemical Analysis; Captopril; Female; Humans; Hyperaldoster

2010
Increased levels of oxidative stress, subclinical inflammation, and myocardial fibrosis markers in primary aldosteronism patients.
    Journal of hypertension, 2010, Volume: 28, Issue:10

    Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; C-Reactive Protein; Cardiomyopathies; Case-Control S

2010
Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice.
    The Journal of clinical investigation, 2010, Volume: 120, Issue:9

    Topics: Aldosterone; Animals; Blood Pressure; Cardiomegaly; Cardiovascular Diseases; Fibrosis; Heart; Hypert

2010
Association of DNA polymorphisms within the CYP11B2/CYP11B1 locus and postoperative hypertension risk in the patients with aldosterone-producing adenomas.
    Urology, 2010, Volume: 76, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; China; Cytochro

2010
Salt-induced cardiac hypertrophy and interstitial fibrosis are due to a blood pressure-independent mechanism in Wistar rats.
    The Journal of nutrition, 2010, Volume: 140, Issue:10

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agen

2010
Severity of obstructive sleep apnea is related to aldosterone status in subjects with resistant hypertension.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2010, Aug-15, Volume: 6, Issue:4

    Topics: Adult; Aged; Aldosterone; Comorbidity; Cross-Sectional Studies; Drug Resistance; Female; Humans; Hyp

2010
HO-1 attenuates hypertension-induced inflammation/oxidative stress: support from Bartter's/Gitelman's patients.
    American journal of hypertension, 2010, Volume: 23, Issue:9

    Topics: Aldosterone; Angiotensin II; Bartter Syndrome; Blood Pressure; Heme Oxygenase-1; Humans; Hypertensio

2010
Genetic analyses of the chimeric CYP11B1/CYP11B2 gene in a Korean family with glucocorticoid-remediable aldosteronism.
    Journal of Korean medical science, 2010, Volume: 25, Issue:9

    Topics: Adolescent; Aldosterone; Asian People; Cytochrome P-450 CYP11B2; Dexamethasone; Family; Female; Gluc

2010
Endogenous ouabain and the renin-angiotensin-aldosterone system: distinct effects on Na handling and blood pressure in human hypertension.
    Journal of hypertension, 2011, Volume: 29, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Kidney Tubules; Linear Models; Mal

2011
Cardiovascular correlates of insulin resistance in normotensive and hypertensive African Americans.
    Metabolism: clinical and experimental, 2011, Volume: 60, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Black or African American; Blood Glucose; Blood Pressure; Cardiac Ou

2011
Clinical relevance of dietary salt intake on aldosterone and the aldosterone-to-renin ratio as screening parameters for primary aldosteronism.
    Clinical nephrology, 2010, Volume: 74, Issue:3

    Topics: Age Factors; Aldosterone; Antihypertensive Agents; Cross-Sectional Studies; Female; Humans; Hyperald

2010
High plasma aldosterone concentration is a novel risk factor of cognitive impairment in patients with hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Cognition; Cognition Disorders; Female; Humans; Hyperte

2011
A mother/daughter case of familial hyperaldosteronism.
    Clinical cardiology, 2010, Volume: 33, Issue:12

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Antihypertensive Agents; Biomarkers; Blo

2010
A genome-wide association study of hypertension-related phenotypes in a Japanese population.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:11

    Topics: Adult; Aged; Alcohol Drinking; Aldosterone; Asian People; Biomarkers; Blood Pressure; Body Mass Inde

2010
Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects?
    Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:12

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2010
Misdiagnosis of two cases of primary aldosteronism owing to failure of computed tomography to detect adrenal microadenoma.
    The American journal of the medical sciences, 2010, Volume: 340, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Diagnostic Errors; Fem

2010
Dietary sodium, aldosterone, and left ventricular mass changes during long-term inhibition of the renin-angiotensin system.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:5

    Topics: Adult; Aged; Aldosterone; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypert

2010
A novel atrial natriuretic peptide based therapeutic in experimental angiotensin II mediated acute hypertension.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:6

    Topics: Acute Disease; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Atrial Natriuretic Fac

2010
The relationship between osteopontin and adiponectin in patients with essential hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2010, Volume: 32, Issue:6

    Topics: Adiponectin; Aged; Aldosterone; C-Reactive Protein; Female; Humans; Hypertension; Male; Middle Aged;

2010
[Variants of surgical management for severe arterial hypertension combined with type 2 diabetes mellitus].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2010, Volume: 16, Issue:2

    Topics: Adult; Aged; Aldosterone; Atherosclerosis; Cadaver; Diabetes Mellitus, Type 2; Female; Follow-Up Stu

2010
Prenatal overexposure to glucocorticoids programs renal 11β-hydroxysteroid dehydrogenase type 2 expression and salt-sensitive hypertension in the rat.
    Journal of hypertension, 2011, Volume: 29, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Animals, Newborn; Blood Pressure;

2011
Amlodipine suppressed cardiac gene expression of brain natriuretic peptide, transforming growth factor-β₁ and fibronectin mediated by aldosterone in male stroke-prone spontaneously hypertensive rats.
    The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:12

    Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium C

2010
High prevalence of liddle syndrome phenotype among hypertensive US Veterans in Northwest Louisiana.
    Journal of clinical hypertension (Greenwich, Conn.), 2010, Volume: 12, Issue:11

    Topics: Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Bicarbonates; Blood Pressure; Cross-S

2010
Overnight rostral fluid shift and obstructive sleep apnea in treatment resistant hypertension: connecting the dots clarifies the picture.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 56, Issue:6

    Topics: Aldosterone; Blood Volume; Drug Resistance; Fluid Shifts; Humans; Hypertension; Insulin Resistance;

2010
Current diagnosis and treatment of primary aldosteronism.
    Expert review of cardiovascular therapy, 2010, Volume: 8, Issue:11

    Topics: Adrenal Cortex; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocortic

2010
Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Drug Interactions; Electrop

2011
Aldosterone-to-renin ratio and home blood pressure in subjects with higher and lower sodium intake: the Ohasama study.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:3

    Topics: Aged; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Sectional Studies; F

2011
Aldosterone/Mineralocorticoid receptor stimulation induces cellular senescence in the kidney.
    Endocrinology, 2011, Volume: 152, Issue:2

    Topics: Acetylglucosaminidase; Aldosterone; Animals; Blood Pressure; Blotting, Western; Cells, Cultured; Cel

2011
The development of a whole-cell based medium throughput screening system for the discovery of human aldosterone synthase (CYP11B2) inhibitors: old drugs disclose new applications for the therapy of congestive heart failure, myocardial fibrosis and hyperte
    The Journal of steroid biochemistry and molecular biology, 2011, Volume: 125, Issue:1-2

    Topics: Aldosterone; Cytochrome P-450 CYP11B2; Drug Discovery; Drug Evaluation, Preclinical; Fibrosis; Heart

2011
Adrenal venous sampling but not computed tomography is essential before undertaking adrenalectomy for primary aldosteronism.
    Surgery, 2011, Volume: 149, Issue:6

    Topics: Adenoma; Adrenal Glands; Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hyperaldostero

2011
The dangers of mandating policy in the absence of clear evidence.
    Heart (British Cardiac Society), 2011, Volume: 97, Issue:4

    Topics: Aldosterone; Evidence-Based Medicine; Humans; Hypertension; Sodium Chloride, Dietary

2011
[Effects of Bai-Chuan capsule on left ventricular hypertrophy and correlative indexes].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:8

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Apiaceae; Blood Pressure; Capsules; C

2010
Aldosterone alters the participation of endothelial factors in noradrenaline vasoconstriction differently in resistance arteries from normotensive and hypertensive rats.
    European journal of pharmacology, 2011, Mar-11, Volume: 654, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Collagen Type I; Endothelium, Vascular; Gene Expression Regula

2011
A rare case of ACTH-independent macronodular adrenal hyperplasia associated with aldosterone-producing adenoma.
    Internal medicine (Tokyo, Japan), 2011, Volume: 50, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aldost

2011
Medicine. The genetics of primary aldosteronism.
    Science (New York, N.Y.), 2011, Feb-11, Volume: 331, Issue:6018

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Animals; Disease Mode

2011
K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension.
    Science (New York, N.Y.), 2011, Feb-11, Volume: 331, Issue:6018

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Cell Line; Cell Proli

2011
Primary aldosteronism among newly diagnosed and untreated hypertensive patients in a Swedish primary care area.
    Scandinavian journal of primary health care, 2011, Volume: 29, Issue:1

    Topics: Adrenal Glands; Adult; Aged; Aldosterone; Blood Specimen Collection; Female; Fludrocortisone; Humans

2011
Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men.
    Pharmacogenetics and genomics, 2011, Volume: 21, Issue:6

    Topics: Aldosterone; Blood Pressure; Diabetes Mellitus, Type 2; Gene Frequency; Genotype; Hemodynamics; Huma

2011
Relative contributions of mitochondria and NADPH oxidase to deoxycorticosterone acetate-salt hypertension in mice.
    Kidney international, 2011, Volume: 80, Issue:1

    Topics: Acetophenones; Albuminuria; Aldosterone; Animals; Blood Pressure; Cell Line; Desoxycorticosterone; D

2011
Verification and evaluation of aldosteronism demographics in the Taiwan Primary Aldosteronism Investigation Group (TAIPAI Group).
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2011, Volume: 12, Issue:3

    Topics: Adenoma; Aldosterone; Cohort Studies; Demography; Female; Humans; Hyperaldosteronism; Hypertension;

2011
Cardiovascular changes in patients with primary aldosteronism after surgical or medical treatment.
    Journal of endocrinological investigation, 2012, Volume: 35, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adult; Aged; Aldosterone; Blood

2012
Higher aldosterone and lower N-terminal proatrial natriuretic peptide as biomarkers of salt sensitivity in the community.
    European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2011, Volume: 18, Issue:4

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Down-Regulation; Fe

2011
Arterial hypertension in obesity: relationships with hormone and anthropometric parameters.
    European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2011, Volume: 18, Issue:2

    Topics: Adult; Aldosterone; Biomarkers; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory

2011
Eplerenone potentiates protective effects of amlodipine against cardiovascular injury in salt-sensitive hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:7

    Topics: Aldosterone; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Drug Th

2011
Impact of aldosterone synthase gene C-344T polymorphism on IgA nephropathy.
    Renal failure, 2011, Volume: 33, Issue:4

    Topics: Adult; Aldosterone; Biopsy; Cytochrome P-450 CYP11B2; Disease Progression; Female; Genotype; Glomeru

2011
Mineralocorticoid receptor activation: a major contributor to salt-induced renal injury and hypertension in young rats.
    American journal of physiology. Renal physiology, 2011, Volume: 300, Issue:6

    Topics: Acute Kidney Injury; Aldosterone; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Ani

2011
Frequency of familial hyperaldosteronism type 1 in a hypertensive pediatric population: clinical and biochemical presentation.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Child; Child, Preschool; Chile; Comorbidity; Cross-S

2011
New take on the role of angiotensin II in cardiac hypertrophy and fibrosis.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:6

    Topics: Aldosterone; Angiotensin II; Animals; Cardiomegaly; Fibrosis; Humans; Hypertension; Inflammation; Mi

2011
Is familial hyperaldosteronism underdiagnosed in hypertensive children?
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:6

    Topics: Aldosterone; Blood Pressure; Child; Chile; Comorbidity; Cytochrome P-450 CYP11B2; Family Health; Gen

2011
A clinical phenotype mimicking essential hypertension in a newly discovered family with Liddle's syndrome.
    American journal of hypertension, 2011, Volume: 24, Issue:8

    Topics: Adolescent; Adult; Aged; Aldosterone; Amiloride; Epithelial Sodium Channels; Female; Humans; Hyperte

2011
High prevalence of autonomous aldosterone secretion among patients with essential hypertension.
    European journal of clinical investigation, 2011, Volume: 41, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aged; Aldosterone; Blood Pressure; Case-Control St

2011
NKCC2 is activated in Milan hypertensive rats contributing to the maintenance of salt-sensitive hypertension.
    Pflugers Archiv : European journal of physiology, 2011, Volume: 462, Issue:2

    Topics: Aldosterone; Animals; Blood Pressure; Diuretics; Furosemide; Humans; Hypertension; Kidney; Male; Pro

2011
Dysregulation of renal transient receptor potential melastatin 6/7 but not paracellin-1 in aldosterone-induced hypertension and kidney damage in a model of hereditary hypomagnesemia.
    Journal of hypertension, 2011, Volume: 29, Issue:7

    Topics: Aldosterone; Animals; Claudins; Disease Models, Animal; Hypercalciuria; Hypertension; Membrane Prote

2011
Effect of the plasminogen-plasmin system on hypertensive renal and cardiac damage.
    Journal of hypertension, 2011, Volume: 29, Issue:8

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Fibrinolysin; Fibrosis

2011
Diagnosis of glucocorticoid-remediable aldosteronism in hypertensive children.
    Hormone research in paediatrics, 2011, Volume: 76, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Child; Chimera; Cytochrome P-450 CYP11B2; Dexamethasone; Female; Glu

2011
Transcriptome analysis of aldosterone-regulated genes in human vascular endothelial cell lines stably expressing mineralocorticoid receptor.
    Molecular and cellular endocrinology, 2011, Jul-20, Volume: 341, Issue:1-2

    Topics: Aldosterone; Animals; Aorta; Cell Line; Endothelial Cells; Endothelium, Vascular; Gene Expression; G

2011
[Flaccid paraplegia revealing an adenoma of Conn: a case report].
    Annales de cardiologie et d'angeiologie, 2012, Volume: 61, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Biomarkers; Fem

2012
[Correction of aldosterone level as marker of RAAS dysfunction in patients with arterial hypertension degree II-III and chronic kidney diseases].
    Eksperimental'naia i klinicheskaia farmakologiia, 2011, Volume: 74, Issue:4

    Topics: Aged; Aldosterone; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme In

2011
Association of the aldosterone synthase gene -344T>C polymorphism with essential hypertension and glucose homeostasis: a case-control study in a Han Chinese population.
    Clinical and experimental pharmacology & physiology, 2011, Volume: 38, Issue:9

    Topics: Aldosterone; Asian People; Blood Glucose; Blood Pressure; Case-Control Studies; China; Cytochrome P-

2011
Impact of leptin-mediated sympatho-activation on cardiovascular function in obese mice.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:2

    Topics: Aldosterone; Animals; Blood Pressure; Cardiovascular System; Dietary Fats; Heart Rate; Hypertension;

2011
Coexisting renal artery aneurysm and adrenal adenoma in resistant hypertension.
    Archives of cardiovascular diseases, 2011, Volume: 104, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Aneurysm; Female; Humans; Hyperaldosteronism; Hyperte

2011
Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice.
    The Journal of clinical investigation, 2011, Volume: 121, Issue:7

    Topics: Aldosterone; Animals; Aquaporin 2; Aromatic-L-Amino-Acid Decarboxylases; Cyclooxygenase 2; Dopamine;

2011
Aldosterone, mortality, and acute ischaemic events in coronary artery disease patients outside the setting of acute myocardial infarction or heart failure.
    European heart journal, 2012, Volume: 33, Issue:2

    Topics: Age Factors; Aged; Aldosterone; Angioplasty, Balloon, Coronary; Body Mass Index; Brain Ischemia; C-R

2012
Plasma catecholamines in Nigerians with primary hypertension.
    Ethnicity & disease, 2011,Spring, Volume: 21, Issue:2

    Topics: Adult; Aldosterone; Black People; Blood Glucose; Case-Control Studies; Catecholamines; Epinephrine;

2011
Resistant hypertension and undiagnosed primary hyperaldosteronism detected by use of a computerized database.
    Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:7

    Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Clinical Pharmacy Information Systems; D

2011
Aldosterone induces electrical remodeling independent of hypertension.
    International journal of cardiology, 2013, Apr-05, Volume: 164, Issue:2

    Topics: Aldosterone; Animals; Hypertension; Male; Rats; Rats, Wistar; Tachycardia, Ventricular; Ventricular

2013
Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway.
    The Journal of clinical investigation, 2011, Volume: 121, Issue:8

    Topics: Aldosterone; Animals; Hypertension; Kidney; Kidney Diseases; Male; Mice; Mice, Transgenic; Models, B

2011
Effects of antihypertensive treatment on endothelial function in postmenopausal hypertensive women. A significant role for aldosterone inhibition.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2011, Volume: 12, Issue:4

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Demography; Endothelium, Vascular; Female; Fol

2011
A comparison between sphygmomanometer-based and ambulatory blood pressure monitoring in acute salt loading and depletion protocol.
    Clinics (Sao Paulo, Brazil), 2011, Volume: 66, Issue:5

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure Monitoring, Ambulatory; Diuretics; Female; Furosemide

2011
Endothelial progenitor cells in primary aldosteronism: a biomarker of severity for aldosterone vasculopathy and prognosis.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:10

    Topics: Adenoma; Adult; Aged; Aldosterone; Apoptosis; Arteries; Biomarkers; C-Reactive Protein; Cell Count;

2011
Aldosterone-to-renin ratio and nocturnal blood pressure decline in a general population: the Ohasama study.
    Journal of hypertension, 2011, Volume: 29, Issue:10

    Topics: Aged; Aldosterone; Blood Pressure; Circadian Rhythm; Cross-Sectional Studies; Female; Humans; Hypert

2011
Blood pressure, thyroid-stimulating hormone, and thyroid disease prevalence in primary aldosteronism and essential hypertension.
    American journal of hypertension, 2011, Volume: 24, Issue:12

    Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension; Insulin Resist

2011
[Effect of qianyang recipe on correlated indices of hypertension rats of gan-yang hyperactivity syndrome].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2011, Volume: 31, Issue:7

    Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Calcitonin Gene-Related Peptide; Dr

2011
Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:5

    Topics: Aldosterone; Animals; Aorta, Thoracic; Blood Pressure; Blotting, Western; Cyclic GMP; Disease Models

2011
Pattern of adrenal morphology and function in patients with acromegaly.
    European journal of clinical investigation, 2012, Volume: 42, Issue:3

    Topics: Acromegaly; Adrenal Glands; Adult; Aldosterone; Female; Glucose Tolerance Test; Human Growth Hormone

2012
Angiotensin II acts through the angiotensin 1a receptor to upregulate pendrin.
    American journal of physiology. Renal physiology, 2011, Volume: 301, Issue:6

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anion Transport Prote

2011
A role for cardiotrophin-1 in myocardial remodeling induced by aldosterone.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:6

    Topics: Aldosterone; Animals; Blood Pressure; Blotting, Western; Collagen; Cytokines; Disease Models, Animal

2011
Role of the renin-angiotensin-aldosterone system in the enhancement of salt sensitivity caused by prenatal protein restriction in stroke-prone spontaneously hypertensive rats.
    The Journal of nutritional biochemistry, 2012, Volume: 23, Issue:8

    Topics: Aldosterone; Animals; Cytochrome P-450 CYP11B2; Diet, Protein-Restricted; Female; Hypertension; Kidn

2012
Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome.
    Journal of hypertension, 2011, Volume: 29, Issue:11

    Topics: Aldosterone; Angiotensin II; Animals; Animals, Genetically Modified; Blood Platelets; Humans; Hypert

2011
Aldosterone-producing adenoma formation in the adrenal cortex involves expression of stem/progenitor cell markers.
    Endocrinology, 2011, Volume: 152, Issue:12

    Topics: Adenoma; Adrenal Cortex; Adrenal Glands; Aldosterone; Biomarkers; Cell Proliferation; Gene Expressio

2011
L/N-type calcium channel blocker suppresses reflex aldosterone production induced by antihypertensive action.
    Heart and vessels, 2012, Volume: 27, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Block

2012
What is the role of aldosterone excess in resistant hypertension and how should it be investigated and treated?
    Current cardiology reports, 2011, Volume: 13, Issue:6

    Topics: Aldosterone; Eplerenone; Female; Humans; Hyperaldosteronism; Hyperkalemia; Hypertension; Male; Miner

2011
Hyperparathyroidism in patients with primary aldosteronism: cross-sectional and interventional data from the GECOH study.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:1

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Cross-Sectional Studies; Data In

2012
Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats.
    Die Pharmazie, 2011, Volume: 66, Issue:9

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aldosterone; Animals; Antihypertensive Agents; Biomar

2011
Conn's syndrome unmasked by thiazide-induced hypokalaemia.
    British journal of hospital medicine (London, England : 2005), 2011, Volume: 72, Issue:9

    Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Blood Pressure Monitoring, Ambulatory; Diagnosis,

2011
Plasma aldosterone levels and development of insulin resistance: prospective study in a general population.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Aldosterone; Blood Glucose; Cross-Sectional Studie

2011
Targeted mutation of SLC4A5 induces arterial hypertension and renal metabolic acidosis.
    Human molecular genetics, 2012, Mar-01, Volume: 21, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Aldosterone; Animals; Atrial Natriuretic Factor; Blo

2012
Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice.
    American journal of hypertension, 2012, Volume: 25, Issue:3

    Topics: Actins; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cellular Sene

2012
The epistasis between vascular homeostasis genes is apparent in essential hypertension.
    Atherosclerosis, 2012, Volume: 220, Issue:2

    Topics: Adult; Aldosterone; Analysis of Variance; Blood Pressure; Case-Control Studies; Chi-Square Distribut

2012
PVN adenovirus-siRNA injections silencing either NOX2 or NOX4 attenuate aldosterone/NaCl-induced hypertension in mice.
    American journal of physiology. Heart and circulatory physiology, 2012, Feb-01, Volume: 302, Issue:3

    Topics: Adenoviridae; Aldosterone; Animals; Autonomic Nervous System; Blood Pressure; Female; Genetic Therap

2012
T regulatory lymphocytes prevent aldosterone-induced vascular injury.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:2

    Topics: Adaptive Immunity; Adoptive Transfer; Aldosterone; Animals; Endothelium, Vascular; Hypertension; Imm

2012
[Aldosterone/renin ratio in the diagnosis of primary aldosteronism].
    Medicina, 2011, Volume: 71, Issue:6

    Topics: Adult; Aldosterone; Argentina; Blood Pressure; Cross-Sectional Studies; Female; Humans; Hyperaldoste

2011
Reversibility of the effects of aliskiren in the renal versus systemic circulation.
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:2

    Topics: Adult; Aged; Aldosterone; Amides; Analysis of Variance; Angiotensin II; Antihypertensive Agents; Blo

2012
Lack of validation of a same-day outpatient protocol for determination of salt sensitivity of blood pressure.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Clinical Protocols; Furosemide; Humans; Hypertension; Inpatients

2012
Endogenous aldosterone is involved in vascular calcification in rat.
    Experimental biology and medicine (Maywood, N.J.), 2012, Volume: 237, Issue:1

    Topics: Aldosterone; Alkaline Phosphatase; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals

2012
Adrenalectomy improves increased carotid intima-media thickness and arterial stiffness in patients with aldosterone producing adenoma.
    Atherosclerosis, 2012, Volume: 221, Issue:1

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone; Analysis of Vari

2012
The effects of ethanol upon hydric balance and arterial pressure in rats: folic acid as a possible hypotensor.
    Life sciences, 2012, Feb-27, Volume: 90, Issue:9-10

    Topics: Alcohol Drinking; Alcohol-Induced Disorders; Aldosterone; Animals; Antihypertensive Agents; Creatini

2012
Activation of mineralocorticoid receptors in the rostral ventrolateral medulla is involved in hypertensive mechanisms in stroke-prone spontaneously hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:4

    Topics: Aldosterone; Animals; Blood Pressure; Eplerenone; Hypertension; Male; Medulla Oblongata; Microinject

2012
Myocardial migration by fibroblast progenitor cells is blood pressure dependent in a model of angII myocardial fibrosis.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cell Movement; Collagen; Fibroblasts; Fibrosis

2012
Sex-specific effects of spironolactone on blood pressure in gonadectomized male and female Wistar rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2012, Volume: 44, Issue:4

    Topics: Aldosterone; Animals; Blood Pressure; Female; Gonads; Humans; Hypertension; Male; Mineralocorticoid

2012
11β-hydroxysteroid dehydrogenase type 2 polymorphisms and activity in a Chilean essential hypertensive and normotensive cohort.
    American journal of hypertension, 2012, Volume: 25, Issue:5

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Case-Control Studies; Chile; Cohort Studie

2012
Primary aldosteronism: are we missing the wood for the trees?
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2012, Volume: 44, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Pract

2012
Neuroendocrine changes and natriuresis in response to social stress in rats.
    Stress and health : journal of the International Society for the Investigation of Stress, 2012, Volume: 28, Issue:3

    Topics: Aldosterone; Analysis of Variance; Animals; Behavior, Animal; Catecholamines; Chronic Disease; Corti

2012
Lessons from Africa: the importance of measuring plasma renin and aldosterone in resistant hypertension.
    The Canadian journal of cardiology, 2012, Volume: 28, Issue:3

    Topics: Africa; Aldosterone; Antihypertensive Agents; Black or African American; Drug Resistance; Female; Hu

2012
Antihypertensive and cardiorenal protective effects of SM-368229, a novel mineralocorticoid receptor antagonist, in aldosterone/salt-treated rats.
    Pharmacology, 2012, Volume: 89, Issue:1-2

    Topics: Acetylglucosaminidase; Aldosterone; Animals; Antihypertensive Agents; Benzoxazines; Biomarkers; Bloo

2012
Pattern of adrenal hormonal secretion in patients with adrenal adenomas: the relevance of aldosterone in arterial hypertension.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:4

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenoco

2012
Unilateral primary aldosteronism with spontaneous remission after long-term spironolactone therapy.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:4

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Antihypertensive Agents; Cardiomegaly; Enalapril; Human

2012
The development of hypertension and hyperaldosteronism in a rodent model of life-long obesity.
    Endocrinology, 2012, Volume: 153, Issue:4

    Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Body Weight; Cytochrome P-450 CYP11B2; Dietary

2012
A case of myelolipoma with bilateral adrenal hyperaldosteronism cured after unilateral adrenalectomy.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:5

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Comorbidity; Humans; Hyperaldosteronism; Hypert

2012
Biphasic time course of the changes in aldosterone biosynthesis under high-salt conditions in Dahl salt-sensitive rats.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:5

    Topics: Adrenal Glands; Aldosterone; Animals; Disease Models, Animal; Hypertension; Immunohistochemistry; Ma

2012
Urinary corticosteroid excretion predicts left ventricular mass and proteinuria in chronic kidney disease.
    Clinical science (London, England : 1979), 2012, Volume: 123, Issue:5

    Topics: Aged; Aldosterone; Biomarkers; Cross-Sectional Studies; Desoxycorticosterone; Female; Gas Chromatogr

2012
Effects of proangiotensin-12 infused continuously over 14 days in conscious rats.
    European journal of pharmacology, 2012, May-15, Volume: 683, Issue:1-3

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2012
Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice.
    Kidney international, 2012, Volume: 82, Issue:1

    Topics: Aldosterone; Amiloride; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensi

2012
[Peculiarities of cardiac contractile function in patients with arterial hypertension depending on temperament and anxiety state].
    Klinicheskaia meditsina, 2011, Volume: 89, Issue:6

    Topics: Adult; Aldosterone; Anxiety; Comorbidity; Diastole; Echocardiography; Humans; Hypertension; Hypertro

2011
Blood pressure response to angiotensin II is enhanced in obese Zucker rats and is attributed to an aldosterone-dependent mechanism.
    British journal of pharmacology, 2012, Volume: 166, Issue:8

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Hypertension; Male; Obesity; Ra

2012
The concentration of blood pressure regulating hormones in premenopausal women with isolated systolic hypertension related to hyperthyroidism.
    Neuro endocrinology letters, 2012, Volume: 33, Issue:1

    Topics: Aldosterone; Blood Pressure; Female; Humans; Hypertension; Hyperthyroidism; Renin

2012
Aldosterone-to-renin ratio as a predictor of stroke under conditions of high sodium intake: the Ohasama study.
    American journal of hypertension, 2012, Volume: 25, Issue:7

    Topics: Adult; Aged; Aldosterone; Female; Humans; Hypertension; Incidence; Japan; Male; Middle Aged; Prospec

2012
TASK-3 channel deletion in mice recapitulates low-renin essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Gene Expression Regulation; Humans; Hy

2012
Screening for primary aldosteronism in hypertensive subjects: results from two German epidemiological studies.
    European journal of endocrinology, 2012, Volume: 167, Issue:1

    Topics: Adult; Aged; Aldosterone; Comorbidity; Female; Germany; Health Surveys; Humans; Hyperaldosteronism;

2012
Prediction of primary vs secondary hypertension in children.
    Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:5

    Topics: Adolescent; Aldosterone; Biomarkers; Catecholamines; Child; Child, Preschool; Creatinine; Echocardio

2012
A rare cause of hypertension in a healthy 2-year-old female: questions.
    Pediatric nephrology (Berlin, Germany), 2012, Volume: 27, Issue:11

    Topics: Adrenal Cortex Function Tests; Adrenal Hyperplasia, Congenital; Aldosterone; Antihypertensive Agents

2012
Aldosterone inhibits antifibrotic factors in mouse hypertensive heart.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:6

    Topics: Aldosterone; Animals; Animals, Newborn; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blo

2012
Plasma aldosterone is increased in class 2 and 3 obese essential hypertensive patients despite drug treatment.
    American journal of hypertension, 2012, Volume: 25, Issue:7

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Press

2012
Low plasma renin activity and high aldosterone/renin ratio are associated with untreated isolated systolic hypertension.
    Blood pressure, 2012, Volume: 21, Issue:5

    Topics: Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System;

2012
Dietary sodium intake and cardiovascular mortality: controversy resolved?
    American journal of hypertension, 2012, Volume: 25, Issue:7

    Topics: Aldosterone; Blood Pressure; Cardiovascular Diseases; Cholesterol; Humans; Hypertension; Male; Middl

2012
Leptin and aldosterone in sympathetic activity in resistant hypertension with or without type 2 diabetes.
    Arquivos brasileiros de cardiologia, 2012, Volume: 99, Issue:1

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory;

2012
Polymorphic variation of CYP11B2 predicts postoperative resolution of hypertension in patients undergoing adrenalectomy for aldosterone-producing adenomas.
    International journal of urology : official journal of the Japanese Urological Association, 2012, Volume: 19, Issue:9

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Cytochrome P-450 CYP11

2012
Natriuretic peptide receptor guanylyl cyclase-A protects podocytes from aldosterone-induced glomerular injury.
    Journal of the American Society of Nephrology : JASN, 2012, Volume: 23, Issue:7

    Topics: Acute Kidney Injury; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured;

2012
Macrophage mineralocorticoid receptor signaling plays a key role in aldosterone-independent cardiac fibrosis.
    Endocrinology, 2012, Volume: 153, Issue:7

    Topics: Aldosterone; Angiotensin Amide; Animals; Fibrosis; Heart; Hypertension; Macrophages; Male; Mice; Mic

2012
Aldosterone inhibits the fetal program and increases hypertrophy in the heart of hypertensive mice.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Aldosterone; Animals; Cardiomegaly; Cyclic AMP Response Element-Binding Protein; Female; Fetus; Gene

2012
Basal and postprandial serum levels of gastrin in normotensive and hypertensive adults.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2013, Volume: 35, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Case-Control Studies; Fasting; Female; Gastrins;

2013
[Hypertension-induced fibrosis: a balance story].
    Annales de cardiologie et d'angeiologie, 2012, Volume: 61, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Bone Morphogenetic Proteins; Cardiomegaly; Disease Models, Ani

2012
Long-term food restriction attenuates age-related changes in the expression of renal aldosterone-sensitive sodium transporters in Wistar-Kyoto rats: a comparison with SHR.
    Experimental gerontology, 2012, Volume: 47, Issue:8

    Topics: Aging; Aldosterone; Animals; Body Mass Index; Food Deprivation; Hydrogen Peroxide; Hypertension; Kid

2012
One-hour upright posture is an ideal position for serum aldosterone concentration and plasma renin activity measuring on primary aldosteronism screening.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2012, Volume: 120, Issue:7

    Topics: Adult; Aldosterone; China; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension

2012
Plasma and urinary metanephrines determined by an enzyme immunoassay, but not serum chromogranin A for the diagnosis of pheochromocytoma in patients with adrenal mass.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2012, Volume: 120, Issue:8

    Topics: Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Chromogranin A; Diagnosis, Diff

2012
Aldosterone-producing adrenocortical carcinoma without hypertension.
    The Korean journal of internal medicine, 2012, Volume: 27, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adult; Aldosterone; Biopsy; Femal

2012
Prospective appraisal of the prevalence of primary aldosteronism in hypertensive patients presenting with atrial flutter or fibrillation (PAPPHY Study): rationale and study design.
    Journal of human hypertension, 2013, Volume: 27, Issue:3

    Topics: Aldosterone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Biomarkers; Chi-Square Dis

2013
Different polymorphisms of the mineralocorticoid receptor gene are associated with either glucocorticoid or mineralocorticoid levels in hypertension.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:9

    Topics: Adult; Aldosterone; DNA; Exons; Female; Genotype; Glucocorticoids; Haplotypes; Humans; Hydrocortison

2012
Interferon-γ ablation exacerbates myocardial hypertrophy in diastolic heart failure.
    American journal of physiology. Heart and circulatory physiology, 2012, Sep-01, Volume: 303, Issue:5

    Topics: Aldosterone; Animals; Autophagy; Disease Models, Animal; Disease Progression; Fibrosis; Heart Failur

2012
Hyperparathyroidism can be useful in the identification of primary aldosteronism due to aldosterone-producing adenoma.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Calcium; Comor

2012
Sixteen years experience in six cases of Conn syndrome in Jakarta.
    Acta medica Indonesiana, 2012, Volume: 44, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Alkalosis; Female; Humans; Hyperaldosteronism;

2012
[Differences of blood plasma renin activity, angiotensin II and aldosterone levels in essential or secondary hypertension].
    Zhonghua nei ke za zhi, 2012, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hyperaldosteronism; Hypertensi

2012
Positive association between aldosterone-renin ratio and carotid intima-media thickness in hypertensive children.
    Clinical endocrinology, 2013, Volume: 78, Issue:3

    Topics: Adolescent; Aldosterone; Carotid Intima-Media Thickness; Child; Female; Humans; Hypertension; Male;

2013
Influence of salt intake on target organ damages in treated hypertensive patients.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:5

    Topics: Aged; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antih

2012
Increased microparticle production and impaired microvascular endothelial function in aldosterone-salt-treated rats: protective effects of polyphenols.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Aldosterone; Animals; Antioxidants; Aorta; Arterial Pressure; Cell-Derived Microparticles; Endotheli

2012
Aldosterone and stress-dependent arterial hypertension.
    Bulletin of experimental biology and medicine, 2011, Volume: 152, Issue:2

    Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Blood Pressure; Hypertension; Male; Rats; Stress, Phy

2011
High-circulating leptin levels are associated with increased blood pressure in uncontrolled resistant hypertension.
    Journal of human hypertension, 2013, Volume: 27, Issue:4

    Topics: Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pressure; Blood Pressure Monitoring, A

2013
Cerebrovascular consequences of pseudohyperaldosteronism.
    Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Aged; Aldosterone; Child; Child, Preschool; Cohort Studies; Epithelial Sodium Cha

2012
Task3 potassium channel gene invalidation causes low renin and salt-sensitive arterial hypertension.
    Endocrinology, 2012, Volume: 153, Issue:10

    Topics: Adaptation, Physiological; Adrenal Glands; Aldosterone; Animals; Blood Pressure; Calcium; Cells, Cul

2012
Persistent hypertension after adrenalectomy for an aldosterone-producing adenoma: weight as a critical prognostic factor for aldosterone's lasting effect on the cardiac and vascular systems.
    The Journal of surgical research, 2012, Volume: 177, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Body Mass Index

2012
Aldosterone acting through the central nervous system sensitizes angiotensin II-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Hypertension; Hypothalamus; M

2012
Expression of aldosterone synthase and adrenocorticotropic hormone receptor in adrenal incidentalomas from normotensive and hypertensive patients: Distinguishing subclinical or atypical primary aldosteronism from adrenal incidental
    International journal of molecular medicine, 2012, Volume: 30, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Asymptomatic Diseases; Biomark

2012
Increasing peripheral insulin sensitivity by protein tyrosine phosphatase 1B deletion improves control of blood pressure in obesity.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:5

    Topics: Adrenergic alpha-1 Receptor Agonists; Albuminuria; Aldosterone; Animals; Blood Pressure; Dose-Respon

2012
Transient prehypertensive treatment in spontaneously hypertensive rats: a comparison of losartan and amlodipine regarding long-term blood pressure, cardiac and renal protection.
    International journal of molecular medicine, 2012, Volume: 30, Issue:6

    Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardioton

2012
Generalized glucocorticoid resistance caused by a novel two-nucleotide deletion in the hormone-binding domain of the glucocorticoid receptor gene NR3C1.
    European journal of endocrinology, 2013, Volume: 168, Issue:1

    Topics: Adult; Aldosterone; Animals; Base Sequence; Coronary Artery Disease; COS Cells; Female; Frameshift M

2013
Adrenal histologic findings show no difference in clinical presentation and outcome in primary hyperaldosteronism.
    Annals of surgical oncology, 2013, Volume: 20, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Antihypertensive Agent

2013
Blood pressure has only minor influence on aldosterone-induced oxidative stress and DNA damage in vivo.
    Free radical biology & medicine, 2013, Volume: 54

    Topics: Aldosterone; Animals; Apoptosis; Blood Pressure; Cell Transformation, Neoplastic; Cells, Cultured; C

2013
Association of elevated plasma aldosterone-to-renin ratio with future cardiovascular events in patients with essential hypertension.
    Journal of hypertension, 2012, Volume: 30, Issue:12

    Topics: Adult; Aged; Aldosterone; Asian People; Cardiovascular Diseases; Cohort Studies; Essential Hypertens

2012
Galectin-3 mediates aldosterone-induced vascular fibrosis.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:1

    Topics: Aldosterone; Animals; Blood Pressure; Cells, Cultured; Collagen Type I; Disease Models, Animal; Fibr

2013
Screening for primary aldosteronism in a primary care unit.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2013, Volume: 14, Issue:3

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Cohort Studies; Female; Humans; H

2013
Hypertension caused by primary hyperaldosteronism: increased heart damage and cardiovascular risk.
    Revista espanola de cardiologia (English ed.), 2013, Volume: 66, Issue:1

    Topics: Aged; Aldosterone; Blood Pressure; Cardiovascular Diseases; Cohort Studies; Female; Heart Diseases;

2013
MDR-1 C3435T polymorphism may affect blood pressure in resistant hypertensive patients independently of its effects on aldosterone release.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2014, Volume: 15, Issue:2

    Topics: Adult; Aged; Aldosterone; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transp

2014
Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs: effects of aging and long-term aldosterone infusion.
    American journal of physiology. Heart and circulatory physiology, 2013, Feb-15, Volume: 304, Issue:4

    Topics: Aging; Aldosterone; Animals; Cell Membrane Permeability; Dogs; Female; Hypertension; Hypertrophy, Le

2013
Elevation of angiotensin-II type-1-receptor autoantibodies titer in primary aldosteronism as a result of aldosterone-producing adenoma.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Autoantibodies; Autoimmunity; Diagnosis

2013
Differential predictors of insulin resistance in nondiabetic salt-resistant and salt-sensitive subjects.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:3

    Topics: Adult; Aldosterone; Black People; Blood Glucose; Creatinine; Diet, Sodium-Restricted; Epinephrine; F

2013
Cholecalciferol administration blunts the systemic renin-angiotensin system in essential hypertensives with hypovitaminosis D.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2014, Volume: 15, Issue:1

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Cholecalciferol; Essential Hypertension; Female; Humans; H

2014
Increased dietary sodium is related to severity of obstructive sleep apnea in patients with resistant hypertension and hyperaldosteronism.
    Chest, 2013, Volume: 143, Issue:4

    Topics: Aldosterone; Blood Pressure; Comorbidity; Cross-Sectional Studies; Female; Humans; Hyperaldosteronis

2013
Cardiovascular effects of Tulbaghia violacea Harv. (Alliaceae) root methanolic extract in Dahl salt-sensitive (DSS) rats.
    Journal of ethnopharmacology, 2013, Mar-07, Volume: 146, Issue:1

    Topics: Aldosterone; Allium; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Male; Medicine,

2013
The contributions of muscarinic receptors and changes in plasma aldosterone levels to the anti-hypertensive effect of Tulbaghia violacea.
    BMC complementary and alternative medicine, 2013, Jan-11, Volume: 13

    Topics: Aldosterone; Allium; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Captopril; Heart Ra

2013
Suppression of primary aldosteronism and resistant hypertension by the peroxisome proliferator-activated receptor gamma agonist pioglitazone.
    The American journal of the medical sciences, 2013, Volume: 345, Issue:6

    Topics: Aldosterone; Blood Pressure; Comorbidity; Humans; Hyperaldosteronism; Hypertension; Male; Middle Age

2013
Structural insights into aldosterone synthase substrate specificity and targeted inhibition.
    Molecular endocrinology (Baltimore, Md.), 2013, Volume: 27, Issue:2

    Topics: Aldosterone; Blood Pressure; Catalysis; Crystallography, X-Ray; Cytochrome P-450 CYP11B2; Desoxycort

2013
Role of hypothalamic angiotensin type 1 receptors in pressure overload-induced mineralocorticoid receptor activation and salt-induced sympathoexcitation.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2013, Volume: 36, Issue:6

    Topics: Aldosterone; Animals; Aorta, Thoracic; Blood Pressure; Blotting, Western; Epithelial Sodium Channels

2013
Association of aldosterone with left ventricular mass in hypertension: interaction with plasma fibrinogen levels.
    American journal of hypertension, 2013, Volume: 26, Issue:1

    Topics: Adult; Aged; Aldosterone; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Heart Ventricl

2013
Abnormal aldosterone physiology and cardiometabolic risk factors.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:4

    Topics: Aldosterone; Cross-Sectional Studies; Female; Humans; Hypertension; Incidence; Male; Metabolic Syndr

2013
Dopaminergic modulation of aldosterone secretions on changes of sodium intake in aldosterone-producing adenoma.
    American journal of hypertension, 2002, Volume: 15, Issue:7 Pt 1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Blood Pressure; Diet, Sodium-R

2002
Structural changes in small resistance arteries and left ventricular geometry in patients with primary and secondary hypertension.
    Journal of hypertension, 2002, Volume: 20, Issue:7

    Topics: Adult; Aged; Aldosterone; Arteries; Echocardiography; Female; Heart Ventricles; Humans; Hypertension

2002
Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor.
    Journal of hypertension, 2002, Volume: 20, Issue:7

    Topics: Adrenomedullin; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anim

2002
TIMP-1: a marker of left ventricular diastolic dysfunction and fibrosis in hypertension.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:2

    Topics: Aldosterone; Blood Pressure; Cohort Studies; Collagen; Collagen Type I; Echocardiography; Electrocar

2002
PAI-1 in human hypertension: relation to hypertensive groups.
    American journal of hypertension, 2002, Volume: 15, Issue:8

    Topics: Adult; Aldosterone; Data Interpretation, Statistical; Female; Fibrinogen; Humans; Hypertension; Insu

2002
Soluble cell adhesion molecules in hypertensive concentric left ventricular hypertrophy.
    Journal of hypertension, 2002, Volume: 20, Issue:8

    Topics: Adult; Aged; Aldosterone; Carotid Arteries; Case-Control Studies; Cell Adhesion Molecules; E-Selecti

2002
Contribution of endothelin-1 to renal activator protein-1 activation and macrophage infiltration in aldosterone-induced hypertension.
    Clinical science (London, England : 1979), 2002, Volume: 103 Suppl 48

    Topics: Aldosterone; Analysis of Variance; Animals; Dansyl Compounds; DNA; Electrophoretic Mobility Shift As

2002
Variation at the aldosterone synthase (CYP11B2) locus contributes to hypertension in subjects with a raised aldosterone-to-renin ratio.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:9

    Topics: Aldosterone; Base Sequence; Blood Pressure; Creatinine; Cytochrome P-450 CYP11B2; DNA Primers; Femal

2002
Is cardiovascular remodeling in patients with essential hypertension related to more than high blood pressure? A LIFE substudy. Losartan Intervention For Endpoint-Reduction in Hypertension.
    American heart journal, 2002, Volume: 144, Issue:3

    Topics: Aged; Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood Vess

2002
High plasma adrenomedullin concentrations in patients with high-renin essential hypertension.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2002, Volume: 3, Issue:2

    Topics: Adrenomedullin; Adult; Aldosterone; Humans; Hypertension; Middle Aged; Peptides; Renin

2002
Influence of antihypertensive medication on aldosterone and renin concentration in the differential diagnosis of essential hypertension and primary aldosteronism.
    Clinical endocrinology, 2002, Volume: 57, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Diagnosi

2002
Variant of pre-clinical Cushing's syndrome: hypertension and hypokalemia associated with normoreninemic normoaldosteronism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2002, Volume: 25, Issue:4

    Topics: Adenoma; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Cushing Syndrome; Cyt

2002
[Effect of isosorbide mononitrate on hypotensive action of enalapril in patients with mild and moderate hypertension].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2002, Volume: 13, Issue:73

    Topics: Administration, Oral; Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypert

2002
High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives.
    American journal of hypertension, 2002, Volume: 15, Issue:10 Pt 1

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Humans; Hyperaldost

2002
Aldosterone induces a vascular inflammatory phenotype in the rat heart.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:5

    Topics: Aldosterone; Animals; Blood Pressure; Chemokine CCL2; Coronary Vessels; Cyclooxygenase 2; Endomyocar

2002
Primary hyperaldosteronism as a cause of hypertension.
    Lancet (London, England), 1967, Oct-21, Volume: 2, Issue:7521

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin

1967
Screening for primary aldosteronism: implications of an increased plasma aldosterone/renin ratio.
    Clinical chemistry, 2002, Volume: 48, Issue:11

    Topics: Adult; Aldosterone; Black People; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Age

2002
New insights into the role of aldosterone in cardiorenal disease and the clinical implications. Introduction.
    American heart journal, 2002, Volume: 144, Issue:5 Suppl

    Topics: Aldosterone; Heart Failure; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Randomized

2002
[Selective aldosterone blocker for hypertension and heart failure. Better tolerance than previous drugs].
    MMW Fortschritte der Medizin, 2002, Sep-26, Volume: 144, Issue:39

    Topics: Aldosterone; Clinical Trials as Topic; Eplerenone; Heart Failure; Humans; Hypertension; Spironolacto

2002
Long-term follow-up and cost benefit of adrenalectomy in patients with primary hyperaldosteronism.
    The British journal of surgery, 2002, Volume: 89, Issue:12

    Topics: Adrenalectomy; Aldosterone; Antihypertensive Agents; Blood Pressure; Cost-Benefit Analysis; Female;

2002
Selective aldosterone blockade prevents angiotensin II/salt-induced vascular inflammation in the rat heart.
    Endocrinology, 2002, Volume: 143, Issue:12

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Body Weight; Coronary Disease; Coronary Vessels

2002
Brain natriuretic peptide as a risk marker for incident hypertensive cardiovascular events.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2002, Volume: 25, Issue:5

    Topics: Aged; Aging; Aldosterone; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Catecholamines; Dis

2002
Investigation of the role of aldosterone in hypertension associated with spontaneous pituitary-dependent hyperadrenocorticism in dogs.
    The Journal of small animal practice, 2002, Volume: 43, Issue:11

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldosterone; Animals; Antineoplastic Agen

2002
PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Aldosterone; Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Cell Adhesion Molecules; C

2002
Endothelin receptor blockade lowers plasma aldosterone levels via different mechanisms in primary aldosteronism and high-to-normal renin hypertension.
    Cardiovascular research, 2003, Volume: 57, Issue:1

    Topics: Adrenocorticotropic Hormone; Aldosterone; Endothelin Receptor Antagonists; Female; Humans; Hydrocort

2003
Asymmetry of renal blood flow in patients with moderate to severe hypertension.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:1

    Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Radiography; R

2003
The severe form of hypertension caused by the activating S810L mutation in the mineralocorticoid receptor is cortisone related.
    Endocrinology, 2003, Volume: 144, Issue:2

    Topics: Adult; Aldosterone; Animals; Binding, Competitive; Corticosterone; Cortisone; COS Cells; Female; Hum

2003
Increased salt sensitivity induced by impairment of sensory nerves: is nephropathy the cause?
    Journal of hypertension, 2003, Volume: 21, Issue:2

    Topics: Aldosterone; Animals; Animals, Newborn; Blood Pressure; Capsaicin; Denervation; Diuresis; Drinking;

2003
Myocardial ultrasonic backscatter in hypertension: relation to aldosterone and endothelin.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:2

    Topics: Adult; Aldosterone; Analysis of Variance; Blood Pressure; Echocardiography; Endothelins; Female; Hum

2003
[11 beta-hydroxysteroid dehydrogenase type 2 activity in Chilean patients with hypertension].
    Revista medica de Chile, 2002, Volume: 130, Issue:11

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Case-Control Studies; Chile; Chromatograph

2002
20-HETE and furosemide-induced natriuresis in salt-sensitive essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:3 Pt 2

    Topics: Adult; Aldosterone; Blood Pressure; Female; Furosemide; Humans; Hydroxyeicosatetraenoic Acids; Hyper

2003
Renin-angiotensin-aldosterone system and G-protein beta-3 subunit gene polymorphisms in salt-sensitive essential hypertension.
    Journal of human hypertension, 2003, Volume: 17, Issue:3

    Topics: Adult; Aldosterone; Blood Volume; Female; Genotype; Heterotrimeric GTP-Binding Proteins; Humans; Hyp

2003
Adenovirus-mediated human prostasin gene delivery is linked to increased aldosterone production and hypertension in rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:4

    Topics: Adenoviridae; Aldosterone; Animals; Blood Pressure; Disease Models, Animal; Female; Gene Expression;

2003
[Hormonal interactions of parathormone and calcium metabolism].
    Orvosi hetilap, 2003, Jan-05, Volume: 144, Issue:1

    Topics: Adolescent; Adult; Aged; Aldosterone; Blood Glucose; Bone Density; Bone Resorption; Calcium; Drug Ad

2003
[Vasopressin and renin-aldosterone system in patients with arterial hypertension].
    Klinicheskaia meditsina, 2002, Volume: 80, Issue:12

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System

2002
Dietary salt regulates renal SGK1 abundance: relevance to salt sensitivity in the Dahl rat.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:4

    Topics: Administration, Oral; Aldosterone; Animals; Blood Pressure; Gene Expression Regulation; Hypertension

2003
[Conn syndrome as cause of stubborn hypertension. Which hypertensives should you screen?].
    MMW Fortschritte der Medizin, 2003, Feb-27, Volume: 145, Issue:9

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenergic beta-Antagonists; Aldosterone; Angiotens

2003
Effect of Salvia miltiorrhiza on left ventricular hypertrophy and cardiac aldosterone in spontaneously hypertensive rats.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2002, Volume: 22, Issue:4

    Topics: Aldosterone; Animals; Drugs, Chinese Herbal; Hypertension; Hypertrophy, Left Ventricular; Male; Myoc

2002
Hypertension, angiotensin II, aldosterone, and race.
    Journal of the American College of Cardiology, 2003, Apr-02, Volume: 41, Issue:7

    Topics: Aldosterone; Angiotensin Receptor Antagonists; Antihypertensive Agents; Black People; Eplerenone; Hu

2003
Pathologic quiz case: a 57-year-old man with hypertension and hypokalemia.
    Archives of pathology & laboratory medicine, 2003, Volume: 127, Issue:4

    Topics: Adenocarcinoma, Clear Cell; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldoste

2003
Mineralocorticoid regulation of epithelial Na+ channels is maintained in a mouse model of Liddle's syndrome.
    American journal of physiology. Renal physiology, 2003, Volume: 285, Issue:2

    Topics: Aldosterone; Amiloride; Animals; Disease Models, Animal; Diuretics; Epithelial Cells; Epithelial Sod

2003
Effects of long-acting calcium channel antagonists on neurohumoral factors: comparison of nifedipine coat-core with amlodipine.
    Journal of cardiovascular pharmacology, 2003, Volume: 41 Suppl 1

    Topics: Aged; Aged, 80 and over; Aldosterone; Amlodipine; Blood Pressure; Calcium Channel Blockers; Chemistr

2003
The epithelial Na+ channel: progressing from Liddle's syndrome to essential hypertension.
    Journal of hypertension, 2003, Volume: 21, Issue:5

    Topics: Aldosterone; Black People; Disease Progression; Genetic Predisposition to Disease; Humans; Hypertens

2003
A new mutation, R563Q, of the beta subunit of the epithelial sodium channel associated with low-renin, low-aldosterone hypertension.
    Journal of hypertension, 2003, Volume: 21, Issue:5

    Topics: Adult; Aged; Aldosterone; Amino Acid Sequence; Biomarkers; Black People; Female; Genetic Predisposit

2003
Association of high-altitude systemic hypertension with the deletion allele-of the angiotensin-converting enzyme (ACE) gene.
    International journal of biometeorology, 2003, Volume: 48, Issue:1

    Topics: Adaptation, Physiological; Adult; Aldosterone; Altitude; Case-Control Studies; Gene Deletion; Geneti

2003
Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats.
    American journal of hypertension, 2003, Volume: 16, Issue:5 Pt 1

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Bu

2003
Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin.
    American journal of physiology. Renal physiology, 2003, Volume: 285, Issue:3

    Topics: Aldosterone; Amiloride; Animals; Cell Line; Electric Conductivity; Epithelial Cells; Gene Expression

2003
Aldosterone antagonism and hypertension.
    Clinical cardiology, 2003, Volume: 26, Issue:5

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Physiological Phenomena; Cardi

2003
Combined effects of low-dose oral spironolactone and captopril therapy in a rat model of spontaneous hypertension and heart failure.
    Journal of cardiovascular pharmacology, 2003, Volume: 41, Issue:6

    Topics: Administration, Oral; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriur

2003
Upregulation of ligand, receptor system, and amidating activity of adrenomedullin in left ventricular hypertrophy of severely hypertensive rats: effects of angiotensin-converting enzyme inhibitors and diuretic.
    Journal of hypertension, 2003, Volume: 21, Issue:6

    Topics: Adrenomedullin; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic F

2003
A biallelic gene polymorphism of CYP11B2 predicts increased aldosterone to renin ratio in selected hypertensive patients.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:6

    Topics: Adult; Aldosterone; Alleles; Cytochrome P-450 CYP11B2; Female; Gene Frequency; Genotype; Haplotypes;

2003
Primary aldosteronism and hypertensive disease.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:2

    Topics: Aldosterone; Cross-Sectional Studies; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hypertens

2003
Aldosterone plays a pivotal role in the pathogenesis of thrombotic microangiopathy in SHRSP.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:8

    Topics: Aldosterone; Animals; Antineoplastic Agents, Hormonal; Blood Pressure; Body Weight; Creatinine; Dexa

2003
[Cytokines and remodeling of the heart in patients with congestive heart failure].
    Polskie Archiwum Medycyny Wewnetrznej, 2003, Volume: 109, Issue:1

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Biomarkers; Cardiomyopathy, Dilated; Catecholam

2003
[Humoral markers of endothelial dysfunction in essential hypertension].
    Kardiologiia, 2003, Volume: 43, Issue:7

    Topics: Adult; Aldosterone; Biomarkers; Endothelium, Vascular; Humans; Hypertension; Insulin-Like Growth Fac

2003
[Reninoma: a rare but curable cause of high blood pressure, a case report].
    Annales d'endocrinologie, 2003, Volume: 64, Issue:3

    Topics: Adult; Aldosterone; Enzyme Precursors; Humans; Hypertension; Hypokalemia; Kidney Neoplasms; Renal Ve

2003
Analysis of angiotensin II mediated COX-2 downregulation in angiotensin II- or aldosterone-infused hypertensive rat.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:8

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cyclooxygenase 2; Down-Regulation; Hypertensio

2003
Effects of static magnetic fields on plasma levels of angiotensin II and aldosterone associated with arterial blood pressure in genetically hypertensive rats.
    Bioelectromagnetics, 2003, Volume: 24, Issue:6

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Radiation; Electro

2003
Brain sodium channels and ouabainlike compounds mediate central aldosterone-induced hypertension.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:6

    Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Brain Chemistry; Cardenolides; Digoxin; Heart Rate;

2003
[Organization, contributions and possibilities of a department of clinical research in a French-Canadian center; aldosterone and arterial hypertension].
    L'union medicale du Canada, 1955, Volume: 84, Issue:10

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Biomedical Research; Canada; Humans; Hypertens

1955
Malignant hypertension and hyperaldosteronism.
    Proceedings of the Royal Society of Medicine, 1956, Volume: 49, Issue:11

    Topics: Adrenal Cortex; Adrenal Cortex Diseases; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hype

1956
Malignant hypertension and hyperaldosteronism.
    Proceedings of the Royal Society of Medicine, 1956, Volume: 49, Issue:11

    Topics: Adrenal Cortex; Adrenal Cortex Diseases; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hype

1956
Malignant hypertension and hyperaldosteronism.
    Proceedings of the Royal Society of Medicine, 1956, Volume: 49, Issue:11

    Topics: Adrenal Cortex; Adrenal Cortex Diseases; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hype

1956
Malignant hypertension and hyperaldosteronism.
    Proceedings of the Royal Society of Medicine, 1956, Volume: 49, Issue:11

    Topics: Adrenal Cortex; Adrenal Cortex Diseases; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hype

1956
Studies on aldosterone. II. Hypertension as a cumulative effect of aldosterone administration.
    Canadian journal of biochemistry and physiology, 1957, Volume: 35, Issue:1

    Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Pharmaceutical Prep

1957
Studies on aldosterone. II. Hypertension as a cumulative effect of aldosterone administration.
    Canadian journal of biochemistry and physiology, 1957, Volume: 35, Issue:1

    Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Pharmaceutical Prep

1957
Studies on aldosterone. II. Hypertension as a cumulative effect of aldosterone administration.
    Canadian journal of biochemistry and physiology, 1957, Volume: 35, Issue:1

    Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Pharmaceutical Prep

1957
Studies on aldosterone. II. Hypertension as a cumulative effect of aldosterone administration.
    Canadian journal of biochemistry and physiology, 1957, Volume: 35, Issue:1

    Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Pharmaceutical Prep

1957
Aldosterone and hypertension.
    Archives internationales de pharmacodynamie et de therapie, 1957, Mar-01, Volume: 110, Issue:1

    Topics: Aldosterone; Humans; Hypertension

1957
Hyperaldosteronism and malignant hypertension.
    Ugeskrift for laeger, 1957, Aug-15, Volume: 119, Issue:33

    Topics: Aldosterone; Humans; Hypertension

1957
Production of experimental hypertension by aldosterone.
    Acta endocrinologica, 1957, Volume: 26, Issue:4

    Topics: Aldosterone; Desoxycorticosterone; Humans; Hypertension

1957
[Urinary excretion of aldosterone-like substances in hypertensive vascular disease].
    Folia endocrinologica; mensile di incretologia e incretoterapia, 1957, Volume: 10, Issue:5

    Topics: Adrenal Cortex Hormones; Aldosterone; Body Fluids; Electrolytes; Humans; Hypertension

1957
Malignant hypertension, adrenal hyperplasia and depletion of potassium.
    Scottish medical journal, 1957, Volume: 2, Issue:12

    Topics: Adrenal Cortex; Adrenal Cortex Diseases; Aldosterone; Humans; Hyperplasia; Hypertension; Hypertensio

1957
Further studies on urinary aldosterone in human arterial hypertension.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1958, Volume: 97, Issue:3

    Topics: Aldosterone; Body Fluids; Humans; Hypertension

1958
Antihypertensive effects of an aldosterone antagonist.
    Science (New York, N.Y.), 1958, Jun-13, Volume: 127, Issue:3311

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Mineralocorticoid Recept

1958
ALDOSTERONE antagonists as antihypertensive agents.
    The American journal of cardiology, 1958, Volume: 2, Issue:6

    Topics: Aldosterone; Antihypertensive Agents; Humans; Hypertension; Mineralocorticoid Receptor Antagonists

1958
Studies on new diuretic compounds: spirolactone and chlorothiazide.
    Canadian Medical Association journal, 1958, Dec-01, Volume: 79, Issue:11

    Topics: Acetazolamide; Aldosterone; Chlorothiazide; Diuretics; Hypertension; Mineralocorticoid Receptor Anta

1958
Prevention by adrenal-regeneration hypertension by an aldosterone-blocker.
    Endocrinology, 1959, Volume: 64, Issue:2

    Topics: Adrenal Gland Diseases; Adrenalectomy; Aldosterone; Humans; Hypertension; Mineralocorticoid Receptor

1959
[Hyperaldosteronism with adenomatous hyperplasia of the adrenals in a case of hypertension with refractory edema].
    Schweizerische medizinische Wochenschrift, 1959, Jan-24, Volume: 89, Issue:4

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Glands; Aldosterone; Edema; Humans; Hyperaldostero

1959
Aldosteronism and hypertension: the influence of complete adrenalectomy upon essential hypertension in a child.
    Pediatrics, 1959, Volume: 23, Issue:6

    Topics: Adrenalectomy; Aldosterone; Child; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension;

1959
Primary hyperaldosteronism and related hypertension. Surgical management.
    Archives of surgery (Chicago, Ill. : 1960), 1961, Volume: 82

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension

1961
Body fluid and electrolyte composition in arterial hypertension. II. Studies in mineralocorticoid hypertension.
    The Journal of clinical investigation, 1961, Volume: 40

    Topics: Aldosterone; Body Fluids; Electrolytes; Humans; Hypertension; Mineralocorticoids

1961
Primary aldosteronism versus hypertensive disease with secondary aldosteronism.
    Recent progress in hormone research, 1961, Volume: 17

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

1961
Aldosteronism and hypertension. Primary aldosteronism versus hypertensive disease with secondary aldosteronism.
    Archives of internal medicine, 1961, Volume: 107

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

1961
Aldosterone excretion in essential hypertension.
    The Journal of clinical endocrinology and metabolism, 1960, Volume: 20

    Topics: Aldosterone; Biological Transport; Body Fluids; Essential Hypertension; Humans; Hypertension

1960
Studies of the pathogenesis of human hypertension. The adrenal cortex and renal pressor mechanism.
    Annals of internal medicine, 1961, Volume: 55

    Topics: Adrenal Cortex; Aldosterone; Angiotensin Amide; Hypertension; Kidney; Vasoconstrictor Agents

1961
Study of a large steroid spectrum in normal subjects and hypertensive patients.
    Acta endocrinologica, 1960, Volume: 35

    Topics: Adrenal Cortex Hormones; Aldosterone; Body Fluids; Hypertension; Pregnanediol; Steroids

1960
Angiotensin, aldosterone and human arterial hypertension.
    Canadian Medical Association journal, 1961, Feb-25, Volume: 84

    Topics: Aldosterone; Angiotensin Amide; Angiotensins; Body Fluids; Hypertension

1961
Spironolactone in hypertensive patients. Oligemic and antihypertensive effects.
    Archives of internal medicine, 1961, Volume: 108

    Topics: Aldosterone; Antihypertensive Agents; Blood Volume; Diuretics; Humans; Hypertension; Mineralocortico

1961
[Hypertension and aldosterone].
    Terapevticheskii arkhiv, 1960, Volume: 32

    Topics: Aldosterone; Hypertension

1960
Secondary hyperaldosteronism associated with hypertension.
    Medical times, 1961, Volume: 89

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

1961
Primary aldosteronism with severe hypertension relieved by adrenalectomy.
    The Medical journal of Australia, 1961, Aug-12, Volume: 48(2)

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hy

1961
[Urinary excretion of aldosterone in essential hypertension. Investigations by a chemical method].
    Folia endocrinologica; mensile di incretologia e incretoterapia, 1960, Volume: 13

    Topics: Aldosterone; Body Fluids; Essential Hypertension; Humans; Hypertension

1960
[Daily rhythm of the secretion of aldosterone in patients with hypertension].
    Terapevticheskii arkhiv, 1961, Volume: 33

    Topics: Aldosterone; Humans; Hypertension; Periodicity

1961
[On the intervention of the angiotensin-aldosterone system in the pathogenesis of arterial hypertension].
    Revista clinica espanola, 1961, Feb-15, Volume: 80

    Topics: Aldosterone; Angiotensin Amide; Angiotensins; Hypertension

1961
Aldosteronism and arterial hypertension.
    The Medical clinics of North America, 1961, Volume: 45

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

1961
Relation of aldosterone secretion to hypertensive vascular disease.
    Circulation research, 1961, Volume: 9

    Topics: Aldosterone; Biological Transport; Cell Communication; Humans; Hypertension

1961
[The urinary excretion of aldosterone in hypertensive patients].
    Nihon Naibunpi Gakkai zasshi, 1961, Jan-20, Volume: 36

    Topics: Aldosterone; Body Fluids; Humans; Hypertension

1961
Primary aldosteronism--a new and curable hypertensive syndrome.
    Arizona medicine, 1961, Volume: 18

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Syndrome

1961
Urinary aldosterone and hypertension.
    Circulation, 1961, Volume: 24

    Topics: Aldosterone; Humans; Hypertension

1961
[Conn's syndrome and essential arterial hypertension].
    Il Progresso medico, 1960, Aug-15, Volume: 16

    Topics: Aldosterone; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension

1960
Essential hypertension and aldosterone.
    Circulation, 1961, Volume: 23

    Topics: Aldosterone; Essential Hypertension; Humans; Hypertension

1961
Remediable hypertension.
    Maryland state medical journal, 1959, Volume: 8

    Topics: Aldosterone; Humans; Hypertension; Kidney; Kidney Diseases; Pheochromocytoma

1959
[Natruresis and aldosterone excretion in essential hypertension].
    Schweizerische medizinische Wochenschrift, 1959, Apr-04, Volume: 89

    Topics: Aldosterone; Biological Transport; Body Fluids; Essential Hypertension; Humans; Hypertension; Sodium

1959
[Venous hypertension and hyperproduction of aldosterone: experimental research].
    Atti della Societa italiana di cardiologia, 1959, Volume: 21(2)

    Topics: Adrenal Glands; Aldosterone; Cardiovascular System; Humans; Hypertension

1959
Primary aldosteronism: a case with severe hypertension.
    The American journal of medicine, 1960, Volume: 28

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

1960
Electrolyte and corticosteroid studies in a 15-year-old girl with primary aldosteronism and malignant hypertension.
    Metabolism: clinical and experimental, 1960, Volume: 9

    Topics: Adolescent; Adrenal Cortex Hormones; Aldosterone; Electrolytes; Female; Humans; Hyperaldosteronism;

1960
[Quantitative determination of aldosterone in urine of patients with hypertension].
    Terapevticheskii arkhiv, 1959, Volume: 31

    Topics: Aldosterone; Humans; Hypertension

1959
[Secondary hyperaldosteronism in the course of arterial hypertension].
    La Presse medicale, 1960, Jan-02, Volume: 68

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Vascular Diseases

1960
An evaluation of the electrocardiogram and the acidity of the urine as a screening test for primary aldosteronism.
    The American journal of the medical sciences, 1959, Volume: 238

    Topics: Aldosterone; Electrocardiography; Humans; Hyperaldosteronism; Hypertension

1959
[Aldosterone production of the adrenal gland in experimental renal hypertension].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1960, Mar-01, Volume: 15

    Topics: Adrenal Glands; Aldosterone; Humans; Hypertension; Hypertension, Renal

1960
Effects of angiotensin infusions on aldosterone and electrolyte excretion in normal subjects and patients with hypertension and adrenocortical disorders.
    British medical journal, 1962, Jun-09, Volume: 1, Issue:5292

    Topics: Adrenal Cortex; Adrenal Cortex Diseases; Aldosterone; Angiotensins; Body Fluids; Electrolytes; Human

1962
[On the effects of aldosterone antagonists on high blood pressure].
    Medizinische Klinik, 1962, Feb-09, Volume: 57

    Topics: Aldosterone; Humans; Hypertension; Mineralocorticoid Receptor Antagonists

1962
Aldosterone secretion in hypertensive diseases.
    British medical journal, 1962, Mar-10, Volume: 1, Issue:5279

    Topics: Aldosterone; Humans; Hypertension; Lipid Metabolism

1962
The effects of spironolactone and chlorthalidone on arterial pressure.
    Lancet (London, England), 1962, Jun-02, Volume: 1, Issue:7240

    Topics: Aldosterone; Arterial Pressure; Blood Pressure; Chlorthalidone; Diuretics; Humans; Hypertension; Min

1962
Primary hyperaldosteronism, a curable form of hypertension.
    Journal of the Medical Association of Georgia, 1962, Volume: 51

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

1962
Primary aldosteronism. Case observed in a patient subjected previously to thoracolumbar sympathectomy.
    Archives of internal medicine, 1962, Volume: 109

    Topics: Aldosterone; Chlorothiazide; Humans; Hyperaldosteronism; Hypertension; Sympathectomy

1962
Effect of thiazide diuretics on plasma volume, body electrolytes, and excretion of aldosterone in hypertension.
    Circulation, 1961, Volume: 24

    Topics: Aldosterone; Biological Transport; Blood Volume; Chlorothiazide; Electrolytes; Hypertension; Plasma

1961
New approaches in the study of cardiovascular disease: aldosterone, renin, hypertension and juxtaglomerular cells.
    Federation proceedings, 1961, Volume: 20

    Topics: Adrenal Cortex; Aldosterone; Cardiovascular Diseases; Humans; Hypertension; Juxtaglomerular Apparatu

1961
Surgical treatment of hypertension -- primary aldosteronism. A review of 13 cases.
    The New England journal of medicine, 1962, 01-25, Volume: 266

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Essential Hypertension; Humans; Hyperaldoster

1962
Effect of chlorothiazide upon aldosterone excretion and sodium and potassium balance in essential hypertension.
    The Journal of laboratory and clinical medicine, 1962, Volume: 60

    Topics: Aldosterone; Body Fluids; Chlorothiazide; Essential Hypertension; Humans; Hypertension; Potassium; S

1962
Influence of alterations in sodium intake on urinary aldosterone response to corticotropin in normal individuals and patients with essential hypertension.
    Metabolism: clinical and experimental, 1962, Volume: 11

    Topics: Adrenocorticotropic Hormone; Aldosterone; Diet; Essential Hypertension; Humans; Hypertension; Nutrit

1962
An explanation of hypertension produced by narrowing the renal artery.
    Perspectives in biology and medicine, 1963, Volume: 6

    Topics: Aldosterone; Humans; Hypertension; Hypertension, Renal; Natriuresis; Renal Artery; Renin

1963
The effect of aldosterone on electrolytes and on digital vascular reactivity to 1-norepinephrine in normotensive, hypertensive, and hypotensive subjects.
    American heart journal, 1963, Volume: 65

    Topics: Aldosterone; Blood Flow Velocity; Blood Pressure; Blood Pressure Determination; Electrolytes; Humans

1963
Further evidence for a role of the renin-angiotensin system in regulation of aldosterone secretion.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1963, Volume: 112

    Topics: Aldosterone; Humans; Hypertension; Renin; Renin-Angiotensin System

1963
[Mechanism of the development of renal hypertension].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1962, Volume: 53(Supl)

    Topics: Aldosterone; Epinephrine; Humans; Hypertension; Hypertension, Renal; Kidney; Norepinephrine; Renin

1962
Humoral factors in essential hypertension.
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1963, Volume: 28

    Topics: Aldosterone; Essential Hypertension; Humans; Hypertension; Renin

1963
[Urinary aldosterone in subjects with hypertension].
    Archivio per le scienze mediche, 1963, Volume: 115

    Topics: Aldosterone; Humans; Hypertension

1963
[Aspects of the hormonal regulation of aldosterone biosynthesis].
    Folia endocrinologica, 1963, Volume: 16

    Topics: Adrenocorticotropic Hormone; Aldosterone; Humans; Hypertension; Lipogenesis; Pineal Gland; Tissue Ex

1963
[Sodium metabolism and hypertension].
    Schweizerische medizinische Wochenschrift, 1963, Aug-17, Volume: 93

    Topics: Aldosterone; Humans; Hypertension; Hypertension, Renal; Kidney; Sodium

1963
Juxtaglomerular cells, aldosterone, renin and hypertension.
    Bulletin of the New York Academy of Medicine, 1962, Volume: 38

    Topics: Aldosterone; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney; Renin

1962
Renal hypertension with elevated aldosterone. Case due to muscular hypertrophy cured by nephrectomy with decline of aldosterone levels to normal.
    Archives of surgery (Chicago, Ill. : 1960), 1963, Volume: 86

    Topics: Aldosterone; Humans; Hypertension; Hypertension, Renal; Hypertrophy; Kidney; Nephrectomy

1963
Hypertension and increased aldosterone excretion associated with unilateral renal artery stenosis.
    Connecticut medicine, 1963, Volume: 27

    Topics: Aldosterone; Humans; Hyperparathyroidism; Hypertension; Hypertension, Pulmonary; Renal Artery Obstru

1963
[Internal secretion and hypertension. Aldosterone and hypertension].
    Nihon Naibunpi Gakkai zasshi, 1962, Nov-20, Volume: 38

    Topics: Aldosterone; Humans; Hypertension

1962
[Influence of angiotensin activity on renal electrolyte and water excretion caused by pretreatment with aldosterone].
    Klinische Wochenschrift, 1963, Jun-15, Volume: 41

    Topics: Aldosterone; Angiotensins; Electrolytes; Hypertension; Kidney; Potassium; Sodium; Sodium, Dietary; W

1963
Influence of aldosterone and angiotensin II on endotoxin shock in the primate.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1963, Volume: 112

    Topics: Aldosterone; Angiotensin II; Animals; Endotoxins; Humans; Hypertension; Primates; Shock; Shock, Sept

1963
The rate of aldosterone secretion in hypertensive patients with demonstrable renal artery stenosis.
    Metabolism: clinical and experimental, 1963, Volume: 12

    Topics: Aldosterone; Humans; Hypertension; Hypertension, Malignant; Renal Artery Obstruction

1963
[Intervention of aldosterone and electrolytes in the pathogenesis of essential hypertension].
    Folia endocrinologica; mensile di incretologia e incretoterapia, 1962, Volume: 15

    Topics: Aldosterone; Electrolytes; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension; Sodium;

1962
[Determination of loosely bound aldosterone in the blood of healthy and sick people].
    Klinische Wochenschrift, 1963, Jan-01, Volume: 41

    Topics: Aldosterone; Humans; Hypertension; Hypertension, Renal; Kidney; Liver Cirrhosis; Nephrotic Syndrome

1963
Isolation of a polar aldosterone-like substance from the urine and adrenal incubates of patients with arterial hypertension.
    Nature, 1963, Feb-16, Volume: 197

    Topics: Aldosterone; Humans; Hypertension

1963
[Influence of aldosterone on the intradermal test with angiotensin].
    Bollettino della Societa italiana di biologia sperimentale, 1963, Mar-31, Volume: 39

    Topics: Aldosterone; Angiotensins; Humans; Hypertension; Intradermal Tests; Skin Tests

1963
[Studies on the urinary excretion of aldosterone. II. On the role of aldosterone in the pathogenesis of some clinical syndromes].
    Folia endocrinologica; mensile di incretologia e incretoterapia, 1962, Volume: 15

    Topics: Aldosterone; Diabetes Insipidus; Edema; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Liv

1962
[Treatment of shock, considered irreversible, with angiotensin and aldosterone].
    Revista medica de Chile, 1963, Volume: 91

    Topics: Aldosterone; Angiotensins; Humans; Hypertension; Shock

1963
Angiotensin pressor inhibition by aldosterone in the rabbit.
    Science (New York, N.Y.), 1963, Aug-23, Volume: 141, Issue:3582

    Topics: Aldosterone; Angiotensin II; Angiotensins; Animals; Blood Pressure; Hypertension; Rabbits; Renin

1963
ALDOSTERONE SECRETION AND VARIOUS FORMS OF HYPERTENSIVE VASCULAR DISEASE.
    Annals of internal medicine, 1963, Volume: 59

    Topics: Adrenal Gland Neoplasms; Aldosterone; Angiotensins; Humans; Hypertension; Ischemia; Renal Artery; Re

1963
[HYPOKALEMIA, ALDOSTERONE EXCRETION AND PRIMARY HYPERALDOSTERONISM].
    Schweizerische medizinische Wochenschrift, 1963, Sep-07, Volume: 93

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Hypokalemia; Kidney; Uri

1963
MALIGNANT HYPERTENSION AND ALDOSTERONE SECRETION. INFLUENCE OF REVERSAL AND PROGRESSION OF THE SYNDROME IN TWO CASES.
    The American journal of medicine, 1963, Volume: 35

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Spironolactone; Urem

1963
EXPERIMENTAL STUDIES ON THE RELATIONSHIP BETWEEN ENDOCRINE ORGANS AND HYPERTENSION IN SPONTANEOUSLY HYPERTENSIVE RATS. II. EFFECTS OF VARIOUS HORMONES ON BLOOD PRESSURE.
    Japanese heart journal, 1963, Volume: 4

    Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Arginine Vasopressin; Blood Pressure; Body Weight

1963
ETIOLOGIC MECHANISMS IN PREHYPERTENSION.
    Current therapeutic research, clinical and experimental, 1963, Volume: 5

    Topics: Aldosterone; Genetics, Medical; Hypertension; Metabolism; Nervous System; Physiology; Prehypertensio

1963
ALDOSTERONE AND CORTICOSTERONE SECRETION RATES IN RATS WITH EXPERIMENTAL RENAL HYPERTENSION.
    Acta endocrinologica, 1963, Volume: 44

    Topics: Aldosterone; Chromatography; Corticosterone; Hypertension; Hypertension, Renal; Kidney; Nephrectomy;

1963
[ALDOSTERONURIA IN DIFFERENT HYPERTENSIVE STATES].
    Archivio "E. Maragliano" di patologia e clinica, 1963, Volume: 19

    Topics: Aldosterone; Body Fluids; Humans; Hypertension; Urine

1963
ALDOSTERONE AND THE EDEMA OF CONGESTIVE HEART FAILURE.
    Archives of internal medicine, 1964, Volume: 113

    Topics: Aldosterone; Chromatography; Diuretics; Edema; Geriatrics; Heart Diseases; Heart Failure; Hypertensi

1964
[RENAL HYPERTENSION].
    Naika. Internal medicine, 1963, Volume: 12

    Topics: Aldosterone; Angiotensins; Blood Vessel Prosthesis; Humans; Hypertension; Hypertension, Renal; Kidne

1963
[HORMONAL FACTORS IN CARDIAC INSUFFICIENCY].
    Studii si cercetari de endocrinologie, 1963, Volume: 14

    Topics: Aldosterone; Angiotensins; Catecholamines; Heart Failure; Humans; Hypertension; Hyperthyroidism; Met

1963
EFFECTS OF ALDOSTERONE AND OTHER ADRENAL HORMONES ON THE BLOOD PRESSURE RESPONSES TO RENIN AND ANGIOTENSIN.
    Canadian Medical Association journal, 1964, Jan-25, Volume: 90

    Topics: Aldosterone; Angiotensins; Animals; Blood Pressure; Corticosterone; Desoxycorticosterone; Female; Hy

1964
VARIATIONS IN PLASMA RENIN CONCENTRATION IN SEVERAL PHYSIOLOGICAL AND PATHOLOGICAL STATES.
    Canadian Medical Association journal, 1964, Jan-25, Volume: 90

    Topics: Addison Disease; Aldosterone; Angiotensins; Blood Chemical Analysis; Hypertension; Hypokalemia; Live

1964
THE RENIN CONTENT OF THE BLOOD OF HUMANS AND DOGS UNDER SEVERAL CONDITIONS.
    Canadian Medical Association journal, 1964, Jan-25, Volume: 90

    Topics: Aldosterone; Blood Chemical Analysis; Diet, Sodium-Restricted; Dogs; Edema; Hyperaldosteronism; Hype

1964
MEASUREMENT OF HUMAN ARTERIAL RENIN ACTIVITY IN SOME PHYSIOLOGICAL AND PATHOLOGICAL STATES.
    Canadian Medical Association journal, 1964, Jan-25, Volume: 90

    Topics: Aldosterone; Angiotensins; Arteries; Arteriosclerosis; Blood Chemical Analysis; Blood Pressure; Diet

1964
RELATIONS BETWEEN RENIN, ALDOSTERONE AND EXPERIMENTAL HYPERTENSION IN RATS.
    Canadian Medical Association journal, 1964, Jan-25, Volume: 90

    Topics: Aldosterone; Blood Pressure; Hypertension; Hypertension, Renal; Kidney; Rats; Renal Artery; Renin; R

1964
INTERACTION BETWEEN ALDOSTERONE SECRETION, SODIUM AND POTASSIUM BALANCE, AND ANGIOTENSIN ACTIVITY IN MAN: STUDIES IN HYPERTENSION AND CIRRHOSIS.
    Canadian Medical Association journal, 1964, Jan-25, Volume: 90

    Topics: Adrenal Glands; Aldosterone; Angiotensins; Blood Pressure; Edema; Humans; Hyperaldosteronism; Hypert

1964
THE ROLE OF THE RENIN-ANGIOTENSIN SYSTEM IN BLOOD PRESSURE REGULATION AND KIDNEY FUNCTION.
    Canadian Medical Association journal, 1964, Jan-25, Volume: 90

    Topics: Adrenal Glands; Aldosterone; Angiotensins; Blood Chemical Analysis; Blood Circulation; Blood Pressur

1964
THE ROLE OF THE RENIN-ANGIOTENSIN SYSTEM IN THE HYPERTENSION ASSOCIATED WITH RENAL VASCULAR DISEASE.
    Canadian Medical Association journal, 1964, Jan-25, Volume: 90

    Topics: Aldosterone; Angiotensins; Blood Chemical Analysis; Hypertension; Hypertension, Renal; Kidney; Kidne

1964
HYPERTENSION DUE TO RENAL ARTERY OCCLUSION SIMULATING PRIMARY ALDOSTERONISM.
    Canadian Medical Association journal, 1964, Jan-25, Volume: 90

    Topics: Aldosterone; Angiotensins; Blood Chemical Analysis; Blood Pressure; Hyperaldosteronism; Hypertension

1964
EXPERIMENTAL STUDIES ON THE RELATIONSHIP BETWEEN ENDOCRINE ORGANS AND HYPERTENSION IN SPONTANEOUSLY HYPERTENSIVE RATS. III. ROLE OF THE ENDOCRINE ORGANS AND HORMONES.
    Japanese heart journal, 1964, Volume: 5

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Animals; Arginine Vasopressin; Cortisone; D

1964
[ALDOSTERONE SECRETION RATE IN VARIOUS DISEASES].
    [Nisshin igaku] The Japanese journal of medical progress, 1963, Volume: 50

    Topics: Aldosterone; Cushing Syndrome; Diabetic Nephropathies; Heart Diseases; Humans; Hyperaldosteronism; H

1963
[DIAGNOSIS AND TREATMENT OF ADDISON'S DISEASE].
    Il Policlinico. Sezione pratica, 1963, Dec-02, Volume: 70

    Topics: Addison Disease; Adrenal Cortex Hormones; Adrenal Insufficiency; Adrenocorticotropic Hormone; Aldost

1963
[NATRIURETIC DRUGS].
    Revista medica de Chile, 1963, Volume: 91

    Topics: Acetazolamide; Aldosterone; Ascites; Chlorothiazide; Dexamethasone; Diabetes Insipidus; Diuresis; Di

1963
ALDOSTERONE SECRETION RATE AND ELECTROLYTE BALANCE STUDIES ON THREE PATIENTS WITH HYPERTENSION. INFLUENCE OF GUANETHIDINE, HYDRALAZINE AND METHYCLOTHIAZIDE.
    Metabolism: clinical and experimental, 1964, Volume: 13

    Topics: Aldosterone; Diet, Sodium-Restricted; Diuretics; Guanethidine; Heart Diseases; Humans; Hydralazine;

1964
DEMONSTRATION BY PRESSOR AND STEROIDOGENIC ASSAYS OF INCREASED RENIN IN LYMPH OF DOGS WITH SECONDARY HYPERALDOSTERONISM.
    Circulation research, 1964, Volume: 14

    Topics: Adrenal Glands; Aldosterone; Angiotensins; Corticosterone; Dogs; Hyperaldosteronism; Hypertension; H

1964
THE DIAGNOSTIC IMPLICATION OF RESTRICTION OF SALT INTAKE AND ADMINISTRATION OF VARIOUS DRUGS IN PRIMARY ALDOSTERONISM.
    The Tohoku journal of experimental medicine, 1964, Feb-25, Volume: 82

    Topics: Aldosterone; Biomedical Research; Cushing Syndrome; Desoxycorticosterone; Diagnosis, Differential; D

1964
THE JUXTAGLOMERULAR APPARATUS AND ALDOSTERONE IN HYPERALDOSTERONISM.
    The Tohoku journal of experimental medicine, 1964, Feb-25, Volume: 82

    Topics: Aldosterone; Angiotensins; Biomedical Research; Carcinoma, Hepatocellular; Cushing Syndrome; Hepatit

1964
STUDIES ON THE MECHANISMS OF HUMAN ARTERIAL HYPERTENSION.
    Diseases of the chest, 1964, Volume: 45

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenal Medulla; Aldosterone; Brain; Hypertension; Hyperten

1964
[ADRENAL CORTEX AND HYPERTENSION].
    Duodecim; laaketieteellinen aikakauskirja, 1964, Volume: 80

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenalectomy; Aldosterone; Angiotensins; Chlorothiazide; D

1964
[ALDOSTERONE AND SPIROLACTONES IN THE CLINICAL TREATMENT OF INTERNAL DISEASES (REVIEW OF THE LITERATURE AND ANALYSIS OF PERSONAL CASES)].
    Sovetskaia meditsina, 1963, Volume: 27

    Topics: Albuminuria; Aldosterone; Blood; Cardiovascular Diseases; Drug Therapy; Humans; Hyperaldosteronism;

1963
[PATHOPHYSIOLOGY AND CLINICAL ASPECTS OF SECONDARY ALDOSTERONISM AND ITS TREATMENT].
    Folia clinica internacional, 1964, Volume: 14

    Topics: Adrenocorticotropic Hormone; Aldosterone; Ascites; Body Fluids; Classification; Dexamethasone; Extra

1964
BLOOD VOLUME, TOTAL BODY WATER AND ALDOSTERONE EXCRETION IN ESSENTIAL HYPERTENSION.
    Clinical science, 1964, Volume: 26

    Topics: Aldosterone; Blood Volume; Blood Volume Determination; Body Fluids; Body Water; Chromium Isotopes; E

1964
EXPERIMENTAL HYPERTENSIONS TREATED WITH CCL-4: MEASUREMENTS OF ADRENAL FUNCTION, VASCULAR RESPONSIVENESS, ANGIOTENSINASE AND CONVERTING ENZYME.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 115

    Topics: Aldosterone; Angiotensins; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; C

1964
STEROID BIOSYNTHESIS BY RAT ADRENAL: DURING DEVELOPMENT OF ADRENAL REGENERATION AND DESOXYCORTICOSTERONE ACETATE-INDUCED HYPERTENSION.
    Endocrinology, 1964, Volume: 74

    Topics: Acetates; Adrenal Glands; Adrenalectomy; Aldosterone; Chromatography; Corticosterone; Desoxycorticos

1964
ANGIOTENSIN, ELECTROLYTES AND ALDOSTERONE.
    Australasian annals of medicine, 1964, Volume: 13

    Topics: Adrenal Glands; Aldosterone; Angiotensins; Animals; Cerebral Cortex; Chlorides; Corticosterone; Dogs

1964
EXPERIMENTAL ASCITES. VI. THE EFFECTS OF HEPATIC VENOUS OUTFLOW OBSTRUCTION AND ASCITES ON ALDOSTERONE SECRETION.
    Surgery, 1964, Volume: 56

    Topics: Adrenal Glands; Aldosterone; Ascites; Blood; Blood Pressure; Budd-Chiari Syndrome; Dogs; Hepatic Vei

1964
[ON CHANGES IN BLOOD VESSEL WALL ELECTROLYTES AND THE ADRENAL CORTEX IN EXPERIMENTAL HYPERTENSION].
    Japanese circulation journal, 1964, Volume: 28

    Topics: Adrenal Cortex; Aldosterone; Aorta; Blood Pressure Determination; Carbon Tetrachloride Poisoning; Co

1964
PRIMARY ALDOSTERONISM: OBSERVATIONS IN SIX CASES AND REVIEW OF DIAGNOSTIC PROCEDURES.
    Medicine, 1964, Volume: 43

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Diabetes Mellitus; Diagnosis, Differen

1964
[SIGNIFICANCE OF ALDOSTERONE IN THE PATHOGENESIS OF THE EDEMATOUS AND HYPERTENSIVE SYNDROME IN KIDNEY DISEASES].
    Terapevticheskii arkhiv, 1964, Volume: 36

    Topics: Aldosterone; Blood; Edema; Glomerulonephritis; Humans; Hyperaldosteronism; Hypertension; Hypertensio

1964
CHANGES IN PLASMA RENIN DURING SODIUM DEPLETION IN MAN.
    The Tohoku journal of experimental medicine, 1964, Jun-25, Volume: 83

    Topics: Aldosterone; Angiotensins; Blood Chemical Analysis; Diet, Sodium-Restricted; Hypertension; Hypertens

1964
ANGIOTENSIN.
    The Journal of the Kansas Medical Society, 1964, Volume: 65

    Topics: Aldosterone; Angiotensins; Blood Pressure; Blood Pressure Determination; Hypertension; Liver; Metabo

1964
BLOOD-PRESSURE HYPERREACTIVITY TO ANGIOTENSIN IN MAN.
    Lancet (London, England), 1964, Dec-19, Volume: 2, Issue:7373

    Topics: Aldosterone; Angiotensins; Blood Pressure; Blood Pressure Determination; Blood Volume; Edema; Fluids

1964
REIN-ANGIOTENSIN AND ALDOSTERONE IN EXPERIMENTAL HYPERTENSION.
    The Tohoku journal of experimental medicine, 1964, Nov-25, Volume: 84

    Topics: Adrenal Glands; Aldosterone; Angiotensins; Animals; Aorta; Blood; Carbon Tetrachloride; Desoxycortic

1964
[ON THE IMPORTANCE OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN THE PATHOGENESIS OF RENAL HYPERTENSION].
    Medizinische Klinik, 1964, Jun-26, Volume: 59

    Topics: Aldosterone; Angiotensins; Diuresis; Hypertension; Hypertension, Renal; Kidney; Metabolism; Natriure

1964
[ON A USEFUL MODIFICATION OF THE METHOD OF URINARY ALDOSTERONE DETERMINATION BY THIN LAYER CHROMATOGRAPHY].
    Minerva medica, 1964, Dec-05, Volume: 55

    Topics: Aldosterone; Chromatography; Chromatography, Thin Layer; Female; Humans; Hypertension; Premenstrual

1964
[POLYCARDIOGRAPHIC INVENTORY, MICROCIRCULATORY ASPECTS AND HUMORAL EFFECTS IN JUVENILE ARTERIAL HYPERTENSION].
    L' Arcispedale S. Anna di Ferrara, 1964, Volume: 17

    Topics: Adolescent; Aldosterone; Angiotensins; Blood; Capillaries; Cardiovascular System; Catecholamines; Ch

1964
[HYPERALDOSTERONURIA IN THE COURSE OF JUVENILE ARTERIAL HYPERTENSION].
    L' Arcispedale S. Anna di Ferrara, 1964, Volume: 17

    Topics: Adolescent; Aldosterone; Body Fluids; Chromatography; Humans; Hypertension; Urine

1964
EFFECT OF ALDOSTERONE ON JUXTAGLOMERULAR INDEX AND ZONA GLOMERULOSA OF NORMOTENSIVE AND HYPERTENSIVE RATS.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 118

    Topics: Adrenal Glands; Aldosterone; Blood Pressure; Blood Pressure Determination; Hypertension; Hypertensio

1965
[INVESTIGATION OF PLASMA ALDOSTERONE AND ALDOSTERONE METABOLISM IN HEALTHY SUBJECTS AND PATIENTS WITH HEART, LIVER AND KIDNEY DISEASE].
    Schweizerische medizinische Wochenschrift, 1965, Mar-20, Volume: 95

    Topics: Aldosterone; Blood; Healthy Volunteers; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Hyp

1965
[ALDOSTERONE AND ARTERIAL HYPERTENSION].
    Acquisitions medicales recentes, 1964

    Topics: Aldosterone; Hypertension; Physiology; Rats; Research

1964
HYPERTENSION AND HYPERSALIMENTATION. I. ALDOSTERONE HYPERTENSION.
    Laboratory investigation; a journal of technical methods and pathology, 1965, Volume: 14

    Topics: Adrenal Glands; Aldosterone; Arteritis; Diet; Heart Diseases; Hypertension; Kidney; Metabolism; Myoc

1965
[ARTERIAL HYPERTENSION, RENIN, ANGIOTENSIN, AND ALDOSTERONE].
    Bruxelles medical, 1965, Jan-10, Volume: 45

    Topics: Aldosterone; Angiotensins; Humans; Hypertension; Renin

1965
NORMAL AND ALTERED FUNCTION OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN MAN: APPLICATIONS IN CLINICAL AND RESEARCH MEDICINE.
    Annals of internal medicine, 1965, Volume: 63

    Topics: Adrenal Glands; Aldosterone; Angiotensins; Edema; Hyperaldosteronism; Hypertension; Kidney; Physiolo

1965
PROLONGED INFUSIONS OF ANGIOTENSIN II AND NOREPINEPHRINE AND BLOOD PRESSURE, ELECTROLYTE BALANCE, AND ALDOSTERONE AND CORTISOL SECRETION IN NORMAL MAN AND IN CIRRHOSIS WITH ASCITES.
    The Journal of clinical investigation, 1965, Volume: 44

    Topics: Aldosterone; Angiotensin II; Angiotensins; Ascites; Blood Pressure; Body Fluids; Dexamethasone; Huma

1965
[Comparative studies on the hypertensive effects of aldosterone and desoxycorticosterone].
    Experientia, 1955, Feb-15, Volume: 11, Issue:2

    Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; Desoxycorticosterone; Humans; Hypertensio

1955
Hypertension caused by renal artery occlusion simulating primary aldosteronism.
    Metabolism: clinical and experimental, 1960, Volume: 9

    Topics: Aldosterone; Disease; Humans; Hyperaldosteronism; Hypertension; Renal Artery

1960
Hypotensive agents and pressor substances. The effect of epinephrine, norepinephrine, angiotensin II, and others on the secretory rate of aldosterone in man.
    JAMA, 1960, Sep-17, Volume: 174

    Topics: Aldosterone; Angiotensin Amide; Angiotensin II; Antihypertensive Agents; Catecholamines; Epinephrine

1960
Aldosterone secretion and primary and malignant hypertension.
    The Journal of clinical investigation, 1960, Volume: 39

    Topics: Aldosterone; Biological Transport; Humans; Hypertension; Hypertension, Malignant; Lipid Metabolism

1960
Electrolyte metabolism and aldosterone secretion in benign and malignant hypertension.
    Annals of internal medicine, 1960, Volume: 53

    Topics: Aldosterone; Electrolytes; Humans; Hypertension; Hypertension, Malignant

1960
The role of aldosterone in man. Evidence for regulation of electrolyte balance and arterial pressure by a renal-adrenal system which may be involved in malignant hypertension.
    JAMA, 1960, Sep-17, Volume: 174

    Topics: Aldosterone; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Hypertension, Malig

1960
Effects of an acute salt load in a case of primary hyperaldo-steronism before and nine months after surgical cure: comparison with normal subjects and patients with essential hypertension before and after reduction of their elevated pressure with drug tre
    The Journal of laboratory and clinical medicine, 1959, Volume: 54

    Topics: Aldosterone; Essential Hypertension; Humans; Hypertension; Sodium Chloride; Sodium Chloride, Dietary

1959
Hypertension and hypokalaemia associated with hypo-aldosteronism.
    Proceedings of the Royal Society of Medicine, 1959, Volume: 52

    Topics: Aldosterone; Child; Humans; Hyperaldosteronism; Hypertension; Hypoaldosteronism; Hypokalemia; Infant

1959
[False Conn syndromes].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1960, Feb-28, Volume: 36

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Medical Records; Potassium; Tetany

1960
Hypertension associated with hypokalemia and alkalosis simulating primary hyperaldosteronism: report of a case.
    Annales medicinae internae Fenniae, 1959, Volume: 48

    Topics: Aldosterone; Alkalosis; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Potassium; Vascular D

1959
On the influence of body water volume and potassium supply on the aldosterone excretion in arterial hypertension.
    Scandinavian journal of clinical and laboratory investigation, 1962, Volume: 14

    Topics: Aldosterone; Biological Transport; Body Composition; Body Water; Diuretics; Humans; Hypertension; Po

1962
[Influence of spirolactones on manifestations of experimental renal hypertension].
    Journal de medecine de Lyon, 1962, Feb-05, Volume: 43

    Topics: Aldosterone; Diuretics; Hypertension; Hypertension, Renal; Kidney; Leadership; Mineralocorticoid Rec

1962
Hypertension and renal loss of potassium.
    Transactions of the American Clinical and Climatological Association, 1961, Volume: 73

    Topics: Aldosterone; Humans; Hypertension; Kidney; Potassium; Potassium Deficiency

1961
Hormones and the pathogenesis of congestive heart failure: vasopressin, aldosterone, and angiotensin II. Further evidence for renal-adrenal interaction from studies in hypertension and in cirrhosis.
    Circulation, 1962, Volume: 25

    Topics: Aldosterone; Angiotensin Amide; Angiotensin II; Heart Defects, Congenital; Heart Failure; Humans; Hy

1962
Experimental vascular disease elicited by aldosterone and renin.
    Endocrinology, 1962, Volume: 71

    Topics: Aldosterone; Angiotensin Amide; Blood Vessels; Disease; Humans; Hypertension; Renin; Vascular Diseas

1962
Aldosteronism and hypertension.
    The Ohio State medical journal, 1962, Volume: 58

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

1962
Urinary aldosterone and hypertension.
    Japanese heart journal, 1962, Volume: 3

    Topics: Aldosterone; Body Fluids; Humans; Hypertension; Ions; Sodium; Sodium, Dietary

1962
[Hypertension and aldosterone].
    Naika. Internal medicine, 1962, Volume: 9

    Topics: Aldosterone; Anions; Humans; Hypertension; Ions; Potassium; Sodium; Sodium, Dietary

1962
[Contribution to the treatment of essential hypertension.(Control of blood pressure, active blood volume, venous pressure, circulation time and mineral metabolism after Repicin and spirolactone medication)].
    Munchener medizinische Wochenschrift (1950), 1962, Feb-02, Volume: 104

    Topics: Aldosterone; Blood Circulation Time; Blood Pressure; Blood Pressure Determination; Blood Volume; Chl

1962
The role of biochemical tests and clinical symptoms in differential diagnosis of primary aldosteronism.
    Kardiologia polska, 2003, Volume: 58, Issue:1

    Topics: Adult; Age Factors; Aged; Aldosterone; Biomarkers; Blood Pressure; Blood Pressure Determination; Dia

2003
Prevalence and role of a raised aldosterone to renin ratio in the diagnosis of primary aldosteronism: a debate on the scientific logic of the use of the ratio in practice.
    Clinical endocrinology, 2003, Volume: 59, Issue:4

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Diagnosis, Differential; Diagnostic Tests, Routine; Hum

2003
Primary aldosteronism, diagnosed by the aldosterone to renin ratio, is a common cause of hypertension.
    Clinical endocrinology, 2003, Volume: 59, Issue:4

    Topics: Aldosterone; Antihypertensive Agents; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hyperte

2003
Genetic determinants of nonmodulating hypertension.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:5

    Topics: Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Epistasis, Genetic; Family Health; Female

2003
Relationship between plasma aldosterone and left ventricular structure and function in patients with essential hypertension.
    Bratislavske lekarske listy, 2003, Volume: 104, Issue:6

    Topics: Aldosterone; Echocardiography; Female; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Re

2003
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients.
    Journal of hypertension, 2003, Volume: 21, Issue:11

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosterone; Female; F

2003
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients.
    Journal of hypertension, 2003, Volume: 21, Issue:11

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosterone; Female; F

2003
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients.
    Journal of hypertension, 2003, Volume: 21, Issue:11

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosterone; Female; F

2003
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients.
    Journal of hypertension, 2003, Volume: 21, Issue:11

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosterone; Female; F

2003
Human adipocytes secrete mineralocorticoid-releasing factors.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Nov-25, Volume: 100, Issue:24

    Topics: Adipocytes; Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Base Sequence; Colforsin; Culture Me

2003
[Primary aldosteronism. A risk factor for aortic dissection?].
    Journal des maladies vasculaires, 2003, Volume: 28, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Aortic Aneurysm; Aortic Dissec

2003
Hypersensitivity of the adrenal cortex to trophic and secretory effects of angiotensin II in Lyon genetically-hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:1

    Topics: Adrenal Cortex; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone

2004
Effect of salt and water intake on epithelial sodium channel mRNA abundance in the kidney of salt-sensitive Sabra rats.
    Clinical and experimental pharmacology & physiology, 2003, Volume: 30, Issue:12

    Topics: Aldosterone; Animals; Disease Models, Animal; Drinking; Epithelial Cells; Hypertension; Kidney Corte

2003
[Influence of exercise on plasma concentration of neuropeptide Y in patients with essential hypertension].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2003, Volume: 15, Issue:87

    Topics: Aldosterone; Catecholamines; Exercise; Female; Humans; Hypertension; Male; Middle Aged; Neuropeptide

2003
Coexistence of different phenotypes in a family with glucocorticoid-remediable aldosteronism.
    Journal of human hypertension, 2004, Volume: 18, Issue:1

    Topics: Adult; Aged; Aldosterone; Cortodoxone; Cytochrome P-450 CYP11B2; Dexamethasone; Female; Genotype; Gl

2004
NAD(P)H oxidase inhibitor prevents blood pressure elevation and cardiovascular hypertrophy in aldosterone-infused rats.
    Biochemical and biophysical research communications, 2004, Jan-16, Volume: 313, Issue:3

    Topics: Acetophenones; Aldosterone; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Collagen; Fibro

2004
Serum potassium level and dietary potassium intake as risk factors for stroke.
    Neurology, 2003, Jun-10, Volume: 60, Issue:11

    Topics: Aged; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Potassium, Dietary; Renin; R

2003
Aldosterone excretion among subjects with resistant hypertension and symptoms of sleep apnea.
    Chest, 2004, Volume: 125, Issue:1

    Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin; Sleep Apnea

2004
Diurnal blood pressure variation in pheochromocytoma, primary aldosteronism and Cushing's syndrome.
    Journal of human hypertension, 2004, Volume: 18, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Blood Pressure; Blood Pressure Determination; Cas

2004
Resistant hypertension, obesity, sleep apnea, and aldosterone: theory and therapy.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Drug Resistance; Humans; Hypertension; Male; Middle Aged; Mode

2004
Ethnic, geographic and dietary influences upon vasoactive hormones and blood pressure among Greenland Inuit and Danes.
    Blood pressure, 2003, Volume: 12, Issue:5-6

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Denmark; Epidemi

2003
Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:4

    Topics: Aldosterone; Animals; Cyclic N-Oxides; Eplerenone; Hypertension; JNK Mitogen-Activated Protein Kinas

2004
From inflammation to fibrosis: a stiff stretch of highway.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Apoptosis; Cell Adhesion Molecules; Collagen

2004
Pathophysiological aspects of experimental myocardial infarction during arterial hypertension.
    Bulletin of experimental biology and medicine, 2003, Volume: 136, Issue:5

    Topics: Adult; Aldosterone; Animals; Blood Pressure; Case-Control Studies; Disease Models, Animal; Humans; H

2003
Impaired 11-beta hydroxysteroid dehydrogenase type 2 activity in sweat gland ducts in human essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenal Cortex Hormones; Adult; Aldosterone; Bicarbonat

2004
Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:3

    Topics: Aldosterone; Chile; Follow-Up Studies; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Italy;

2004
Relations of serum aldosterone to cardiac structure: gender-related differences in the Framingham Heart Study.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Aged; Aldosterone; Antihypertensive Agents; Body Mass Index; Cohort Studies; Cross-Sectional Studies

2004
The many targets of aldosterone.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Aldosterone; Amiloride; Body Water; Cell Size; Endothelial Cells; Endothelium, Vascular; Guanidines;

2004
Diagnosis of primary aldosteronism: value of different screening parameters and influence of antihypertensive medication.
    European journal of endocrinology, 2004, Volume: 150, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertensi

2004
Relationship between hypertensive left ventricular hypertrophy, neurohormonal factors and ventricular arrhythmias in very old patients.
    Acta cardiologica, 2004, Volume: 59, Issue:1

    Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Arrhythmias, Cardiac; Biomarkers; Coronary Ang

2004
Aldosterone antagonist facilitates the cardioprotective effects of angiotensin receptor blockers in hypertensive rats.
    Journal of hypertension, 2004, Volume: 22, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; B

2004
Increased renovascular response to angiotensin II in persons genetically predisposed to arterial hypertension disappears after chronic angiotensin-converting enzyme inhibition.
    Journal of hypertension, 2004, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biomarkers

2004
Eplerenone prevents salt-induced vascular remodeling and cardiac fibrosis in stroke-prone spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:6

    Topics: Acetylcholine; Aldosterone; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Collagen

2004
Primary aldosteronism--careful investigation is essential and rewarding.
    Molecular and cellular endocrinology, 2004, Mar-31, Volume: 217, Issue:1-2

    Topics: Adrenal Gland Diseases; Aldosterone; Diagnosis, Differential; Female; Hospital Units; Humans; Hypera

2004
Vascular synthesis of aldosterone: role in hypertension.
    Molecular and cellular endocrinology, 2004, Mar-31, Volume: 217, Issue:1-2

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Cardi

2004
Impaired endothelium-dependent flow-mediated vasodilation in hypertensive subjects with hyperaldosteronism.
    Circulation, 2004, Jun-15, Volume: 109, Issue:23

    Topics: Adult; Aldosterone; Brachial Artery; Endothelium, Vascular; Female; Hemorheology; Humans; Hyperaldos

2004
Age dependence of the levels of plasma norepinephrine, aldosterone, renin activity and urinary vanillylmandelic acid in normal and essential hypertensives.
    Biological research, 2004, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aldosterone; Child; Child, Preschool; Epinephrine; Female; Humans; H

2004
Aldosterone regulation for 18 years in a case of primary aldosteronism.
    American journal of hypertension, 2004, Volume: 17, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Biomarkers; Calcium Channel Blockers; Humans; Hypera

2004
Aldosterone modulates neural vasomotor response in hypertension: role of calcitonin gene-related peptide.
    Regulatory peptides, 2004, Aug-15, Volume: 120, Issue:1-3

    Topics: Adenine; Adenosine Triphosphate; Aldosterone; Animals; Anti-Arrhythmia Agents; Calcitonin Gene-Relat

2004
Six missense mutations of the epithelial sodium channel beta and gamma subunits in Japanese hypertensives.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:5

    Topics: Aged; Aldosterone; Asian People; Epithelial Sodium Channels; Exons; Female; Genetic Predisposition t

2004
Aldosterone--villain or bystander?
    The New England journal of medicine, 2004, Jul-01, Volume: 351, Issue:1

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin-Angiotensin System; Risk Fac

2004
Serum aldosterone and the incidence of hypertension in nonhypertensive persons.
    The New England journal of medicine, 2004, Jul-01, Volume: 351, Issue:1

    Topics: Aldosterone; Blood Pressure; Female; Heart Ventricles; Humans; Hyperaldosteronism; Hypertension; Hyp

2004
[Promoter variants of aldosterone synthase gene (CYP11B2) and salt-sensitivity of blood pressure].
    Polskie Archiwum Medycyny Wewnetrznej, 2004, Volume: 111, Issue:2

    Topics: Adult; Aldosterone; Alleles; Blood Pressure; Cytochrome P-450 CYP11B2; Diet, Sodium-Restricted; DNA;

2004
Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention.
    The Journal of clinical investigation, 2004, Volume: 114, Issue:4

    Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Diuretics; Endothelin-1; Furosemide; Heterozygote;

2004
Aldosterone-renin ratios in the context of primary care.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:9

    Topics: Aldosterone; Humans; Hypertension; Prevalence; Primary Health Care; Renin

2004
Aldosterone to Renin ratio in a primary care setting: the Bussolengo study.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:9

    Topics: Adult; Age Factors; Aged; Aldosterone; Female; Humans; Hypertension; Italy; Male; Middle Aged; Renin

2004
The current epidemic of primary aldosteronism: causes and consequences.
    Journal of hypertension, 2004, Volume: 22, Issue:10

    Topics: Aldosterone; Disease Outbreaks; Humans; Hyperaldosteronism; Hypertension

2004
The current epidemic of primary aldosteronism: causes and consequences.
    Journal of hypertension, 2004, Volume: 22, Issue:10

    Topics: Aldosterone; Disease Outbreaks; Humans; Hyperaldosteronism; Hypertension; Renin

2004
The current epidemic of primary aldosteronism: causes and consequences.
    Journal of hypertension, 2004, Volume: 22, Issue:10

    Topics: Aldosterone; Disease Outbreaks; Humans; Hyperaldosteronism; Hypertension; Renin

2004
[Effect of modified liberation doxazosin on blood pressure, insulin resistance, and catecholamine secretion in patients with true resistant hypertension].
    Medicina clinica, 2004, Sep-11, Volume: 123, Issue:8

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Catecholamines; Doxazosin; Drug Resistance; Fe

2004
Chronic central infusion of aldosterone leads to sympathetic hyperreactivity and hypertension in Dahl S but not Dahl R rats.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:2

    Topics: Aldosterone; Animals; Baroreflex; Blood Pressure; Cardiotonic Agents; Heart Rate; Hypertension; Inje

2005
Postnatal modulation of prenatally programmed hypertension by dietary Na and ACE inhibition.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 288, Issue:1

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Enalapril; Female; Hype

2005
A1166C polymorphism of angiotensin II type 1 receptor, blood pressure and arterial stiffness in hypertension.
    Journal of hypertension, 2004, Volume: 22, Issue:11

    Topics: Adolescent; Adult; Aged; Aldosterone; Alleles; Blood Flow Velocity; Blood Pressure; Female; Genotype

2004
Cardioprotective effects of vasopeptidase inhibition vs. angiotensin type 1-receptor blockade in spontaneously hypertensive rats on a high salt diet.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:8

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Apoptosis; A

2004
[Renin aldosterone profile in essential hypertension during pregnancy and after delivery].
    Polskie Archiwum Medycyny Wewnetrznej, 2004, Volume: 111, Issue:5

    Topics: Adult; Aldosterone; Blood Pressure; Case-Control Studies; Female; Humans; Hypertension; Postpartum P

2004
[One hypertensive in ten affected? Renaissance of primary hyperaldosteronism].
    MMW Fortschritte der Medizin, 2004, Sep-16, Volume: 146, Issue:38

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cross-Sectional Studies; Diagnosis, Differential; Hum

2004
Aldosterone revisited.
    The New England journal of medicine, 2004, Nov-11, Volume: 351, Issue:20

    Topics: Aldosterone; Humans; Hypertension; Potassium

2004
Aldosterone revisited.
    The New England journal of medicine, 2004, Nov-11, Volume: 351, Issue:20

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists

2004
Aldosterone revisited.
    The New England journal of medicine, 2004, Nov-11, Volume: 351, Issue:20

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Sodium; Sodium, Dietary

2004
[Free urinary cortisol is elevated in patients with low-renin essential hypertension].
    Revista medica de Chile, 2004, Volume: 132, Issue:9

    Topics: Aldosterone; Creatinine; Epidemiologic Methods; Female; Glucocorticoids; Humans; Hydrocortisone; Hyp

2004
Alteration of renal adrenomedullin and its receptor system in the severely hypertensive rat: effect of diuretic.
    Regulatory peptides, 2005, Jan-15, Volume: 124, Issue:1-3

    Topics: Adrenomedullin; Aldosterone; Animals; Collagen Type I; Disease Models, Animal; Diuretics; Gene Expre

2005
Plasma sodium: ignored and underestimated.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Cohort Studies; Cross-Over Studies; Dose-Response Relationship,

2005
The influence of aldosterone on the development of left ventricular geometry and hypertrophy in patients with essential hypertension.
    Japanese heart journal, 2004, Volume: 45, Issue:5

    Topics: Aged; Aldosterone; Body Mass Index; Echocardiography; Female; Heart Ventricles; Humans; Hypertension

2004
Scientists probe aldosterone's role in hypertension and heart disease.
    JAMA, 2004, Dec-08, Volume: 292, Issue:22

    Topics: Aldosterone; Cardiovascular Agents; Cardiovascular Physiological Phenomena; Heart Diseases; Humans;

2004
11beta-Hydroxysteroid dehydrogenase type 2 activity is associated with left ventricular mass in essential hypertension.
    European heart journal, 2005, Volume: 26, Issue:5

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Blood Pressure; Cohort Studies; Cortodoxon

2005
CYP11B2 gene polymorphisms and hypertension in highlanders accustomed to high salt intake.
    Journal of hypertension, 2005, Volume: 23, Issue:1

    Topics: Adult; Aged; Aldosterone; Body Mass Index; Cytochrome P-450 CYP11B2; Environment; Feeding Behavior;

2005
Long-term follow-up after adrenalectomy for primary aldosteronism.
    World journal of surgery, 2005, Volume: 29, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Algorithms; Antihypertensive Ag

2005
Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension.
    BMC medical genetics, 2005, Jan-20, Volume: 6

    Topics: Adult; Aged; Aldosterone; Alleles; Epithelial Sodium Channels; Female; Genetic Predisposition to Dis

2005
Multiple gene approaches to delineate the role of the renin-angiotensin-aldosterone system in nephropathy.
    Journal of hypertension, 2005, Volume: 23, Issue:2

    Topics: Aldosterone; Alleles; Angiotensins; Case-Control Studies; Cytochrome P-450 CYP11B2; Gene Frequency;

2005
Genetic polymorphisms of the renin-angiotensin-aldosterone system and renal insufficiency in essential hypertension.
    Journal of hypertension, 2005, Volume: 23, Issue:2

    Topics: Acute Kidney Injury; Aged; Aldosterone; Case-Control Studies; Female; Humans; Hypertension; Italy; M

2005
Adrenocorticotropic hormone is produced in the ventricle of patients with essential hypertension.
    Journal of hypertension, 2005, Volume: 23, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Aorta; Cardiac Catheterization; Case-Control

2005
Prorenin cryoactivation as a possible cause of normal renin levels in patients with primary aldosteronism.
    Journal of hypertension, 2005, Volume: 23, Issue:2

    Topics: Adenoma; Aldosterone; Chymosin; Enzyme Precursors; Humans; Hyperaldosteronism; Hypertension; Immunor

2005
ACE inhibitors and mineralocorticoid receptor blockade in patients with congestive heart failure.
    Current diabetes reports, 2005, Volume: 5, Issue:1

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Heart Failure; Humans; Hypertension; Mineralo

2005
Fat cells may be the obesity-hypertension link: human adipogenic factors stimulate aldosterone secretion from adrenocortical cells.
    Endocrine research, 2004, Volume: 30, Issue:4

    Topics: Adipocytes; Adrenal Cortex; Adult; Aldosterone; Animals; Cattle; Cells, Cultured; Female; Humans; Hy

2004
Hyperaldosteronism and hypertension: ethnic differences.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:4

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Black People; Blood Pressure; Blood Pressure Monitori

2005
Estrogen depletion differentially affects blood pressure depending on age in Long-Evans rats.
    Endocrine, 2004, Volume: 25, Issue:2

    Topics: Aldosterone; Animals; Blood Pressure; Drinking; Estradiol; Estrogen Replacement Therapy; Female; Hyp

2004
The changes of serum-ACE, plasma renin activity and aldosterone in the diabetics with hypertension.
    The Korean journal of internal medicine, 1986, Volume: 1, Issue:1

    Topics: Adult; Aged; Aldosterone; Diabetes Mellitus; Female; Humans; Hypertension; Male; Middle Aged; Peptid

1986
The syndromes of low-renin hypertension: "separating the wheat from the chaff".
    Arquivos brasileiros de endocrinologia e metabologia, 2004, Volume: 48, Issue:5

    Topics: Adenoma; Adolescent; Adult; Aged; Aldosterone; Child; Diagnosis, Differential; Female; Humans; Hyper

2004
Decreased plasma levels of nitric oxide metabolites, angiotensin II, and aldosterone in spontaneously hypertensive rats exposed to 5 mT static magnetic field.
    Bioelectromagnetics, 2005, Volume: 26, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Radiation; Electro

2005
Adrenocortical carcinoma producing 11-deoxycorticosterone: a rare cause of mineralocorticoid hypertension.
    Journal of endocrinological investigation, 2005, Volume: 28, Issue:1

    Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Catecholamines

2005
The effects of genetic factors on selected indicators of the activity of the sympathoadrenal system and the renin-angiotensin-aldosterone system in twins.
    Kardiologia polska, 2004, Volume: 61, Issue:11

    Topics: Adrenal Glands; Adult; Aldosterone; Blood Pressure; Dopamine; Epinephrine; Female; Humans; Hypertens

2004
Participation of aldosterone in the vascular inflammatory response of spontaneously hypertensive rats: role of the NFkappaB/IkappaB system.
    Journal of hypertension, 2005, Volume: 23, Issue:6

    Topics: Aldosterone; Animals; Antihypertensive Agents; Drug Therapy, Combination; Eplerenone; Hypertension;

2005
Failure of angiotensin II to suppress plasma renin activity in normotensive subjects with a positive family history of hypertension.
    Clinical science (London, England : 1979), 2005, Volume: 109, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Dos

2005
Adrenocortical carcinoma with concomitant myelolipoma in a patient with hyperaldosteronism.
    Archives of pathology & laboratory medicine, 2005, Volume: 129, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adult; Aldosterone; Biomarkers, T

2005
Alterations in aldosterone and angiotensin II levels in salt-induced hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2005, Volume: 27, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Glutathione; Glutathione Disulfid

2005
Validity of plasma aldosterone-to-renin activity ratio in African American and white subjects with resistant hypertension.
    American journal of hypertension, 2005, Volume: 18, Issue:6

    Topics: Alabama; Aldosterone; Biomarkers; Black or African American; Blood Pressure; Female; Humans; Hyperal

2005
Morbid obesity, hypertensive disease and the renin-angiotensin-aldosterone axis.
    Obesity surgery, 2005, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Aldosterone; Analysis of Variance; Anastomosis, Roux-en-Y; Female; Gastric Bypass

2005
Differential effects of angiotensin II type-1 receptor antisense oligonucleotides on renal function in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:1

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Diure

2005
Participation of prostacyclin in endothelial dysfunction induced by aldosterone in normotensive and hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:1

    Topics: Acetylcholine; Aldosterone; Animals; Aorta, Thoracic; Blood Pressure; Drug Administration Schedule;

2005
Aldosterone promotes endothelial dysfunction via prostacyclin independent of hypertension.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:1

    Topics: Aldosterone; Animals; Endothelium, Vascular; Epoprostenol; Humans; Hypertension

2005
Relationship between impaired aldosterone response to adrenocorticotropic hormone and prevalence of hemodialysis in type 2 diabetic patients without azotemia.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Diabetes Mellitus, Type 2; Female; Follow-Up Studie

2005
Quiz page. Secondary hypertension with contralateral pheochromocytoma and aldosteronoma.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Antihypertensive Agent

2005
Prolonged attenuation of cold-induced hypertension by adenoviral delivery of renin antisense.
    Kidney international, 2005, Volume: 68, Issue:2

    Topics: Adenoviridae; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cold Temperature; DNA, Antisense

2005
Aldosterone in heart failure: pathophysiology and treatment.
    Current heart failure reports, 2004, Volume: 1, Issue:4

    Topics: Aldosterone; Death, Sudden, Cardiac; Endothelium, Vascular; Heart Failure; Humans; Hypertension; Min

2004
Plasma aldosterone to renin ratio predicts treatment response in primary aldosteronism: is volume loading needed?
    Blood pressure, 2005, Volume: 14, Issue:4

    Topics: Aldosterone; Diagnosis, Differential; Diagnostic Techniques, Endocrine; Female; Fludrocortisone; Hum

2005
c-Src-dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:4

    Topics: Aldosterone; Animals; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Hypertension; Mal

2005
[Role of hormones in volume regulating kidney function in patients with hypertension].
    Likars'ka sprava, 2005, Issue:4

    Topics: Aldosterone; Atrial Natriuretic Factor; Diuresis; Hormones; Humans; Hypertension; Kidney; Kidney Fun

2005
Low-renin hypertension with relative aldosterone excess is associated with impaired NO-mediated vasodilation.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:4

    Topics: Adult; Aged; Aldosterone; Case-Control Studies; Female; Forearm; Humans; Hyperaldosteronism; Hyperte

2005
Urinary prostasin: a candidate marker of epithelial sodium channel activation in humans.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:4

    Topics: Adult; Aged; Aldosterone; Biomarkers; Blotting, Western; Case-Control Studies; Diuretics; Dose-Respo

2005
Paradoxic activation of the renin-angiotensin system in twin-twin transfusion syndrome: an explanation for cardiovascular disturbances in the recipient.
    Pediatric research, 2005, Volume: 58, Issue:4

    Topics: Adult; Aldosterone; Cardiomyopathies; Cardiovascular System; Down-Regulation; Fatal Outcome; Female;

2005
Angiotensin-converting enzyme 2 (ACE2) and ACE activities display tissue-specific sensitivity to undernutrition-programmed hypertension in the adult rat.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:5

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Blood Press

2005
Simvastatin and losartan enhance nitric oxide and reduce oxidative stress in salt-induced hypertension.
    American journal of hypertension, 2005, Volume: 18, Issue:11

    Topics: Acetylcholine; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta;

2005
Prevalence of primary hyperaldosteronism in mild to moderate hypertension without hypokalaemia.
    Journal of human hypertension, 2006, Volume: 20, Issue:2

    Topics: Aldosterone; Black People; Cross-Over Studies; Female; Humans; Hyperaldosteronism; Hypertension; Hyp

2006
Increased number of aldosterone-sensitive NTS neurons in Dahl salt-sensitive rats.
    Brain research, 2005, Dec-14, Volume: 1065, Issue:1-2

    Topics: Aldosterone; Animals; Cell Count; Hydroxysteroid Dehydrogenases; Hypertension; Immunohistochemistry;

2005
Does aldosterone-to-renin ratio predict the antihypertensive effect of the aldosterone antagonist spironolactone?
    American journal of hypertension, 2005, Volume: 18, Issue:12 Pt 1

    Topics: Aldosterone; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Female; Humans; Hypertens

2005
Role of aldosterone in angiotensin II-induced cardiac and aortic inflammation, fibrosis, and hypertrophy.
    Canadian journal of physiology and pharmacology, 2005, Volume: 83, Issue:11

    Topics: Aldosterone; Angiotensin II; Animals; Aorta; Collagen; Ectodysplasins; Fibrosis; Heart; Hypertension

2005
Neurogenic mechanisms contribute to hypertension in mice with disruption of the K-Cl cotransporter KCC3.
    Circulation research, 2006, Mar-03, Volume: 98, Issue:4

    Topics: Aldosterone; Animals; Calcium; Chlorides; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Mu

2006
Aldosterone-induced abnormal regulation of ENaC and SGK1 in Dahl salt-sensitive rat.
    Biochemical and biophysical research communications, 2006, Mar-10, Volume: 341, Issue:2

    Topics: Aldosterone; Animals; Blotting, Western; Body Weight; Epithelial Sodium Channels; Extracellular Sign

2006
[Microsatellite marker AGAT of the mineralocorticoid receptor gene is associated with plasma renin activity in patients with essential hypertension].
    Revista medica de Chile, 2005, Volume: 133, Issue:12

    Topics: Aldosterone; Alleles; Body Mass Index; Case-Control Studies; Female; Genetic Markers; Genotype; Huma

2005
Increased renal alpha-ENaC and NCC abundance and elevated blood pressure are independent of hyperaldosteronism in vasopressin escape.
    American journal of physiology. Renal physiology, 2006, Volume: 291, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenalectomy; Aldosterone; Animals; Blood Pressure; Co

2006
Cardiac consequences of aldosterone excess in human hypertension.
    American journal of hypertension, 2006, Volume: 19, Issue:1

    Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers;

2006
Role of aldosterone in left ventricular hypertrophy in hypertension.
    American journal of hypertension, 2006, Volume: 19, Issue:1

    Topics: Adrenergic beta-Antagonists; Adrenocortical Adenoma; Adult; Aldosterone; Angiotensin II; Blood Press

2006
Aldosterone and left ventricular hypertrophy in Afro-Caribbean subjects with low renin hypertension.
    American journal of hypertension, 2006, Volume: 19, Issue:1

    Topics: Adult; Aged; Aldosterone; Black People; Blood Pressure; Caribbean Region; Echocardiography; Female;

2006
Too much aldosterone--more common than we ever realized?
    American journal of hypertension, 2006, Volume: 19, Issue:1

    Topics: Adult; Aged; Aldosterone; Black People; Blood Pressure; Caribbean Region; Female; Humans; Hypertensi

2006
Long-term results of adrenalectomy in patients with aldosterone-producing adenomas: multivariate analysis of factors affecting unresolved hypertension and review of the literature.
    The American surgeon, 2005, Volume: 71, Issue:10

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Female; H

2005
Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and failure in low-aldosterone hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 47, Issue:4

    Topics: Aldosterone; Animals; Cardiac Output, Low; Cardiomegaly; Cardiotonic Agents; Coronary Vessels; Corti

2006
Mineralocorticoid receptors and cardiovascular damage: it's not just aldosterone.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 47, Issue:4

    Topics: Aldosterone; Animals; Cardiac Output, Low; Cardiomegaly; Cardiotonic Agents; Corticosterone; Epleren

2006
[Diagnosis and treatment outcome in primary aldosteronism based on a retrospective analysis of 187 cases].
    Orvosi hetilap, 2006, Jan-15, Volume: 147, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Cytochrome P-450 CYP11B2

2006
Obesity-induced hypertension develops in young rats independently of the renin-angiotensin-aldosterone system.
    Experimental biology and medicine (Maywood, N.J.), 2006, Volume: 231, Issue:3

    Topics: Acetylcholine; Aging; Aldosterone; Animals; Blood Glucose; Cardiovascular System; Dietary Fats; Dise

2006
Altered vascular contractility in adult female rats with hypertension programmed by prenatal glucocorticoid exposure.
    The Journal of endocrinology, 2006, Volume: 188, Issue:3

    Topics: Acetylcholine; Aldosterone; Angiotensin II; Animals; Animals, Newborn; Aorta; Corticosterone; Dexame

2006
[Primary hyperaldosteronism: should we pose its systematic detection at health centres?].
    Atencion primaria, 2006, Feb-15, Volume: 37, Issue:2

    Topics: Aldosterone; Blood Chemical Analysis; Clinical Trials as Topic; Humans; Hyperaldosteronism; Hyperten

2006
Effects of enalapril, tempol, and eplerenone on salt-induced hypertension in dahl salt-sensitive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2006, Volume: 28, Issue:2

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Blood

2006
Effect of prepuberal gonadectomy upon aldosterone levels in female and male SHR: interaction between blood pressure and kallikrein kinin system.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2006, Volume: 28, Issue:2

    Topics: Aging; Aldosterone; Animals; Biomarkers; Blood Pressure; Castration; Disease Models, Animal; Disease

2006
Blood pressure reduction in pregnancy by sodium chloride.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:7

    Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Hypoaldosteronism; Pregnancy; Preg

2006
Cardioprotective mechanisms of spironolactone associated with the angiotensin-converting enzyme/epidermal growth factor receptor/extracellular signal-regulated kinases, NAD(P)H oxidase/lectin-like oxidized low-density lipoprotein receptor-1, and Rho-kinas
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:11

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Chemokine CCL2; Coronary Vessels; Er

2005
John Arthur Luetscher, Jr (1903-2005).
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 47, Issue:4

    Topics: Aldosterone; Cardiology; History, 20th Century; Humans; Hypertension; United States

2006
Aldosterone and refractory hypertension: a prospective cohort study.
    American journal of hypertension, 2006, Volume: 19, Issue:4

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Cohort Studies; Drug Resistance; Female; Follo

2006
The prevalence of primary aldosteronism in diabetic patients.
    Journal of clinical hypertension (Greenwich, Conn.), 2006, Volume: 8, Issue:4

    Topics: Aldosterone; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Hyperaldosteronism; H

2006
Activation of brain renin-angiotensin-aldosterone system by central sodium in Wistar rats.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Brain; Brain Chemistry; Chlorides; Epithelial Sodium Channels;

2006
[Use of spironolactone and indapamide in the treatment of low-renin arterial hypertension].
    Terapevticheskii arkhiv, 2006, Volume: 78, Issue:2

    Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Creatinine; Diuretics; Female; Follow-Up Studies; Hu

2006
Decreased pituitary response to insulin-induced hypoglycaemia in young lean male patients with essential hypertension.
    Journal of human hypertension, 2006, Volume: 20, Issue:7

    Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Case-Control Studies; Epinephrine; Growth Hormone

2006
Laparoscopic adrenalectomy for primary hyperaldosteronism: clinical experience with 60 cases.
    Journal of endourology, 2006, Volume: 20, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aged, 80 and over; Aldosterone; Blood

2006
[Blood pressure elevation in obese descendants of parents with essential arterial hypertension and its relation to the renin-angiotensin axis, C-reactive protein, and saline taste sensitivity].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2006, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Aldosterone; C-Reactive Protein; Child; Child, Preschool; Chlorides; Diastole; Fe

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Differential regional haemodynamic changes during mineralocorticoid hypertension.
    Journal of hypertension, 2006, Volume: 24, Issue:6

    Topics: Aldosterone; Animals; Antidiuretic Hormone Receptor Antagonists; Cardiac Output; Coronary Circulatio

2006
Confirmatory testing in normokalaemic primary aldosteronism: the value of the saline infusion test and urinary aldosterone metabolites.
    European journal of endocrinology, 2006, Volume: 154, Issue:6

    Topics: Adult; Aldosterone; False Negative Reactions; Female; Humans; Hyperaldosteronism; Hypertension; Hypo

2006
Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:3

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Body

2006
The antagonism of aldosterone receptor prevents the development of hypertensive heart failure induced by chronic inhibition of nitric oxide synthesis in rats.
    Cardiovascular drugs and therapy, 2006, Volume: 20, Issue:2

    Topics: Actins; Aldosterone; Animals; Blotting, Western; Cytochrome P-450 CYP11B2; Drug Therapy, Combination

2006
Effects of adrenomedullin on cardiac oxidative stress and collagen accumulation in aldosterone-dependent malignant hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:3

    Topics: Adrenomedullin; Aldosterone; Animals; Blood Pressure; Cardiotonic Agents; Collagen; Fibronectins; He

2006
Osteopontin and carotid atherosclerosis in patients with essential hypertension.
    Clinical science (London, England : 1979), 2006, Volume: 111, Issue:5

    Topics: Adult; Aged; Aldosterone; Atherosclerosis; Biomarkers; Carotid Artery Diseases; Carotid Artery, Comm

2006
[Association of aldosterone synthase gene -344T/C polymorphism with plasma aldosterone and angiotensin II concentration in hypertensive patients].
    Zhonghua yi xue za zhi, 2006, Apr-25, Volume: 86, Issue:16

    Topics: Aged; Aldosterone; Angiotensin II; Cytochrome P-450 CYP11B2; Female; Gene Frequency; Genotype; Human

2006
Plasma aldosterone assays: comparison between chemiluminescence-based and RIA methods.
    Clinical chemistry, 2006, Volume: 52, Issue:7

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Luminescent Measurements; Plasma; Radioimmuno

2006
Aldosterone, dietary salt, and renal disease.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 48, Issue:2

    Topics: Albuminuria; Aldosterone; Animals; Cross-Sectional Studies; Humans; Hyperaldosteronism; Hypertension

2006
Insulin sensitivity in patients with primary aldosteronism: a follow-up study.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:9

    Topics: Aldosterone; Antihypertensive Agents; Blood Glucose; Blood Pressure; C-Reactive Protein; Female; Glu

2006
Estrogen and salt sensitivity in the female mRen(2). Lewis rat.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 291, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Estrogens; Female; Gene Expressi

2006
The prevalence of a raised aldosterone-renin ratio (ARR) among new referrals to a hypertension clinic.
    Blood pressure, 2006, Volume: 15, Issue:3

    Topics: Adult; Aged; Aldosterone; Ambulatory Care Facilities; Antihypertensive Agents; Blood Pressure Monito

2006
The liquorice effect on the RAAS differs between the genders.
    Blood pressure, 2006, Volume: 15, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Case-Control Studies; Female; Glycyrrhiza; Humans; Hypertension;

2006
Effects of alcohol withdrawal on blood pressure in hypertensive heavy drinkers.
    Journal of hypertension, 2006, Volume: 24, Issue:8

    Topics: Adult; Aldosterone; Analysis of Variance; Biomarkers; Blood Pressure; Catecholamines; Central Nervou

2006
High frequency of primary hyperaldosteronism among hypertensive patients from a primary care area in Sweden.
    Scandinavian journal of primary health care, 2006, Volume: 24, Issue:3

    Topics: Aged; Aldosterone; Fludrocortisone; Humans; Hyperaldosteronism; Hypertension; Middle Aged; Renin; Sw

2006
Mineralocorticoid-receptor blockade, hypertension and heart failure.
    Nature clinical practice. Endocrinology & metabolism, 2005, Volume: 1, Issue:1

    Topics: Aldosterone; Clinical Trials as Topic; Eplerenone; Heart Failure; Hormone Antagonists; Humans; Hyper

2005
Diagnosis of adenomatous primary aldosteronism in a patient with severe hypertension.
    Nature clinical practice. Endocrinology & metabolism, 2005, Volume: 1, Issue:2

    Topics: Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Algorithms; Humans; Hyperaldosteronism;

2005
Increased aldosterone/renin quotient in obese hypertensive women: a novel role for low-density lipoproteins?
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2006, Volume: 38, Issue:7

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Blood Glucose; Cells, Cultured; Female; Humans

2006
Sanguinarine downregulates AT1a gene expression in a hypertensive rat model.
    Journal of cardiovascular pharmacology, 2006, Volume: 48, Issue:2

    Topics: Aldosterone; Alkaloids; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypert

2006
A WNK in the kidney controls blood pressure.
    Nature genetics, 2006, Volume: 38, Issue:10

    Topics: Aldosterone; Animals; Biological Transport; Blood Pressure; Humans; Hypertension; Kidney; Protein Se

2006
Eplerenone relieves spironolactone-induced painful gynaecomastia in a patient with primary aldosteronism.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:1

    Topics: Administration, Oral; Aldosterone; Clinical Trials as Topic; Eplerenone; Gynecomastia; Humans; Hyper

2007
Cholecalciferol treatment changes urinary sodium-potassium ratio and plasma aldosterone of spontaneously hypertensive rats.
    Clinica chimica acta; international journal of clinical chemistry, 2007, Volume: 376, Issue:1-2

    Topics: Aldosterone; Animals; Blood Pressure; Cholecalciferol; Disease Models, Animal; Hypertension; Potassi

2007
The renal physiology of pendrin (SLC26A4) and its role in hypertension.
    Novartis Foundation symposium, 2006, Volume: 273

    Topics: Absorption; Acid-Base Equilibrium; Aldosterone; Animals; Anion Transport Proteins; Bicarbonates; Blo

2006
Functional effects of genetic variants in the 11beta-hydroxylase (CYP11B1) gene.
    Clinical endocrinology, 2006, Volume: 65, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Animals; Biological Assay; Case-Control Stu

2006
Primary hyperaldosteronism in a patient with end-stage renal disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Follow-Up Studies; Fosinopril

2007
Plasma aldosterone in hypertensive patients on chronic hemodialysis: distribution, determinants and impact on survival.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:8

    Topics: Aged; Aldosterone; Cause of Death; Female; Follow-Up Studies; Health Status; Humans; Hypertension; M

2006
Aldosterone as a key mediator of the cardiometabolic syndrome in primary aldosteronism: an observational study.
    Journal of hypertension, 2007, Volume: 25, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Blood Glucose

2007
Aldosterone and cardiovascular disease: smoke and fire.
    Circulation, 2006, Dec-12, Volume: 114, Issue:24

    Topics: Aldosterone; Cardiovascular Diseases; Electrocardiography; Humans; Hyperaldosteronism; Hypertension;

2006
Association of adrenal steroids with hypertension and the metabolic syndrome in blacks.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Black People; Female; Humans; Hydrocortisone; Hypertension; Male; Me

2007
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adult; Aldosterone; Blood Specimen

2006
[MEN type I presenting hypokalemia and hypertension, complicated with acromegaly, adrenal cortical tumor and rectal carcinoid tumor].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2006, Nov-10, Volume: 95, Issue:11

    Topics: Acromegaly; Adrenalectomy; Adrenocortical Adenoma; Aged; Aldosterone; Carcinoid Tumor; Female; Growt

2006
Reactive oxygen species-dependent hypertension in dopamine D2 receptor-deficient mice.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:3

    Topics: Aldosterone; Animals; Antioxidants; Blood Pressure; Hypertension; Mice; Oxidants; Oxidative Stress;

2007
Abnormally increased endothelin-1 in plasma during the night in obstructive sleep apnea: relation to blood pressure and severity of disease.
    American journal of hypertension, 2007, Volume: 20, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitori

2007
Apparent mineralocorticoid excess manifested in an elderly patient with hypothyroidism.
    American journal of hypertension, 2007, Volume: 20, Issue:1

    Topics: Aged, 80 and over; Aldosterone; Female; Humans; Hypertension; Hypokalemia; Hypothyroidism; Mineraloc

2007
Loss of Vav2 proto-oncogene causes tachycardia and cardiovascular disease in mice.
    Molecular biology of the cell, 2007, Volume: 18, Issue:3

    Topics: Adrenal Glands; Aldosterone; Animals; Aorta; Endothelins; Gene Expression Regulation; Guanine Nucleo

2007
Gender differences in selected zinc metabolism parameters in patients with mild primary arterial hypertension.
    Biological trace element research, 2006,Winter, Volume: 114, Issue:1-3

    Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidas

2006
Hypertension associated with rhabdomyolysis.
    Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hyp

2007
[New concepts in searching for primary aldosteronism in hypertension: advances in screening, confirming and subtyping tests].
    Zhonghua xin xue guan bing za zhi, 2006, Volume: 34, Issue:10

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Renin; Renin-Angiotensin Syst

2006
[Aldosterone-to-renin ratio threshold for screening primary aldosteronism in Chinese hypertensive patients].
    Zhonghua xin xue guan bing za zhi, 2006, Volume: 34, Issue:10

    Topics: Adult; Aged; Aldosterone; China; Clinical Chemistry Tests; Female; Humans; Hyperaldosteronism; Hyper

2006
[Aldosterone/plasma renin activity ratio is a sensitive parameter for screening patients with primary aldosteronism].
    Zhonghua xin xue guan bing za zhi, 2006, Volume: 34, Issue:10

    Topics: Aldosterone; Clinical Chemistry Tests; Follow-Up Studies; Humans; Hyperaldosteronism; Hypertension;

2006
Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: the possible role of local renin-angiotensin system.
    Endocrinology, 2007, Volume: 148, Issue:4

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Bipheny

2007
Interactions between aldosterone and connective tissue growth factor in vascular and renal damage in spontaneously hypertensive rats.
    Journal of hypertension, 2007, Volume: 25, Issue:3

    Topics: Aldosterone; Animals; Aorta; Blood Pressure; Blood Pressure Determination; Cells, Cultured; Connecti

2007
[Causes of delaying diagnosis of primary hyperaldosteronism with adrenal adenoma and strategy therefore].
    Zhonghua yi xue za zhi, 2006, Nov-14, Volume: 86, Issue:42

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Biomarkers, Tumor; Chymo

2006
Plasma aldosterone is related to severity of obstructive sleep apnea in subjects with resistant hypertension.
    Chest, 2007, Volume: 131, Issue:2

    Topics: Adult; Aged; Aldosterone; Case-Control Studies; Female; Humans; Hypertension; Male; Middle Aged; Pol

2007
Clinical and genetic correlates of aldosterone-to-renin ratio and relations to blood pressure in a community sample.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:4

    Topics: Aged; Aldosterone; Blood Pressure; Chromosomes, Human, Pair 11; Female; Genetic Linkage; Genetic Var

2007
Polymorphism of CYP11B2 determines salt sensitivity in Japanese.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:4

    Topics: Aged; Aldosterone; Asian People; Blood Pressure; Cohort Studies; Cysteine; Cytochrome P-450 CYP11B2;

2007
Aldosterone antagonists: silver bullet or just sodium excretion and potassium retention?
    Kidney international, 2007, Volume: 71, Issue:5

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Huma

2007
Role of aldosterone in left ventricular hypertrophy among African-American patients with end-stage renal disease on hemodialysis.
    American journal of nephrology, 2007, Volume: 27, Issue:2

    Topics: Aged; Aldosterone; Black or African American; Diabetes Mellitus; Humans; Hypertension; Hypertrophy,

2007
Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:5

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiac Output, Low;

2007
Hypertension caused by prenatal testosterone excess in female sheep.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 292, Issue:6

    Topics: Aldosterone; Animals; Blood Pressure; Chlorides; Cholesterol; Disease Models, Animal; Dyslipidemias;

2007
Analysis of renin-angiotensin-aldosterone system gene polymorphisms in resistant hypertension.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2007, Volume: 40, Issue:3

    Topics: Aldosterone; Brazil; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease

2007
Enhancement of receptor-operated cation current and TRPC6 expression in arterial smooth muscle cells of deoxycorticosterone acetate-salt hypertensive rats.
    Journal of hypertension, 2007, Volume: 25, Issue:4

    Topics: Aldosterone; Animals; Aorta; Arteries; Blood Pressure; Blotting, Western; Calcium Channels; Desoxyco

2007
Peroxisome proliferator-activated receptor alpha-independent actions of fenofibrate exacerbates left ventricular dilation and fibrosis in chronic pressure overload.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:5

    Topics: Aldosterone; Animals; Cells, Cultured; Chronic Disease; Extracellular Signal-Regulated MAP Kinases;

2007
WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Mar-06, Volume: 104, Issue:10

    Topics: Aldosterone; Animals; Colon; Epithelial Sodium Channels; Hyperkalemia; Hypertension; Mice; Mice, Tra

2007
CYP3A5 and ABCB1 genes influence blood pressure and response to treatment, and their effect is modified by salt.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:5

    Topics: Absorption; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; ATP Binding Cassette Trans

2007
Possibly simultaneous primary aldosteronism and preclinical Cushing's syndrome in a patient with double adenomas of right adrenal gland.
    Endocrine journal, 2007, Volume: 54, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cushing Syndrome; Enzymes; Female; Humans; Hydrocorti

2007
Urinary free cortisol is not a biochemical marker of hypertension.
    American journal of hypertension, 2007, Volume: 20, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adult; Aged; Aldosterone; Biomarkers; Blood Pressure; C

2007
Evolution and hypertension: is the Renin system necessary?
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:6

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angi

2007
Aldosteronism: too much of a good thing. The hormone aldosterone helps the body manage water and sodium. Too much of it is an overlooked cause of high blood pressure.
    Harvard heart letter : from Harvard Medical School, 2007, Volume: 17, Issue:8

    Topics: Adrenal Gland Diseases; Adrenal Glands; Aldosterone; Body Water; Humans; Hyperaldosteronism; Hyperte

2007
[Association of aldosterone synthase gene -344 T/C polymorphism with early renal damage in Han nationality with essential hypertension].
    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2007, Volume: 24, Issue:2

    Topics: Adult; Albumins; Albuminuria; Aldosterone; Asian People; China; Cytochrome P-450 CYP11B2; Female; Ge

2007
Left ventricular hypertrophy and geometry in untreated essential hypertension is associated with blood levels of aldosterone and procollagen type III amino-terminal peptide.
    Circulation journal : official journal of the Japanese Circulation Society, 2007, Volume: 71, Issue:5

    Topics: Aldosterone; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Linear M

2007
Developmental activity of the renin-angiotensin system during the "critical period" modulates later L-NAME-induced hypertension and renal injury.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:1

    Topics: Aging; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles

2007
Prevalence of primary aldosteronism among unselected hypertensive patients: a prospective study based on the use of an aldosterone/renin ratio above 25 as a screening test.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:2

    Topics: Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Mass Screening; Mi

2007
Differential aerobic exercise-induced changes in plasma aldosterone between African Americans and Caucasians.
    Experimental physiology, 2007, Volume: 92, Issue:5

    Topics: Abdominal Fat; Aged; Aldosterone; Black or African American; Blood Pressure; Exercise; Female; Human

2007
Arterial plasma vasopressin and aldosterone predict left ventricular mass in men who develop hypertension over 20 years.
    Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:5

    Topics: Adult; Aldosterone; Analysis of Variance; Antihypertensive Agents; Arteries; Biomarkers; Blood Press

2007
[Conn syndrome].
    Revue de l'infirmiere, 2007, Issue:129

    Topics: Aldosterone; Causality; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypernatremia; Hyperten

2007
The incidentally discovered adrenal mass.
    The New England journal of medicine, 2007, May-10, Volume: 356, Issue:19

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Black People; Humans; Hyperaldosteron

2007
[Determining aldosterone in the adrenal veins in order to establish uni- or bilateral aldosterone production in patients with primary hyperaldosteronism].
    Nederlands tijdschrift voor geneeskunde, 2007, May-05, Volume: 151, Issue:18

    Topics: Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Male;

2007
Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:5

    Topics: Aldosterone; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Body Weight; Cytokines;

2007
Primary hyperaldosteronism: returning to the limelight?
    Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:6

    Topics: Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

2007
Unilateral adrenal hyperplasia.
    World journal of surgery, 2007, Volume: 31, Issue:8

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; R

2007
[Primary aldosteronism caused by aldosteronoma: problems in the etiologic diagnosis].
    Arquivos brasileiros de endocrinologia e metabologia, 2007, Volume: 51, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Diagnosis, Differential; Fem

2007
Synergistic induction of osteopontin by aldosterone and inflammatory cytokines in mesangial cells.
    Journal of cellular biochemistry, 2008, Feb-01, Volume: 103, Issue:2

    Topics: Aldosterone; Animals; Chemotaxis, Leukocyte; Drug Synergism; Hypertension; Interleukin-1beta; Mesang

2008
The influence of serum aldosterone and the aldosterone-renin ratio on pulse wave velocity in hypertensive patients.
    Journal of hypertension, 2007, Volume: 25, Issue:6

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Lipids; Mid

2007
Renal cysts and hypokalemia in primary aldosteronism: results of long-term follow-up after treatment.
    Journal of hypertension, 2007, Volume: 25, Issue:7

    Topics: Adrenalectomy; Aldosterone; Follow-Up Studies; Humans; Hyperaldosteronism; Hypertension; Hypokalemia

2007
Insulin resistance and hyperinsulinemia are related to plasma aldosterone levels in hypertensive patients.
    Diabetes care, 2007, Volume: 30, Issue:9

    Topics: Aged; Aldosterone; Cross-Sectional Studies; Female; Glucose; Humans; Hyperinsulinism; Hypertension;

2007
Polycystic ovary syndrome: implications of corticotropin in the regulation of blood pressure, aldosterone, and androgen secretion.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:2

    Topics: Adrenocorticotropic Hormone; Aldosterone; Biomarkers; Blood Pressure; Female; Humans; Hypertension;

2007
Captopril test can give misleading results in patients with suspect primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:2

    Topics: Aldosterone; Captopril; Clinical Laboratory Techniques; Cohort Studies; Female; Humans; Hyperaldoste

2007
A polymorphic GT short tandem repeat affecting beta-ENaC mRNA expression is associated with low renin essential hypertension.
    American journal of hypertension, 2007, Volume: 20, Issue:7

    Topics: Adult; Aldosterone; Blood Pressure; Case-Control Studies; Chile; Dinucleotide Repeats; Epithelial So

2007
Effects of fenofibrate on cardiac remodeling in aldosterone-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Extracellular Matrix; Fenofibrate; Fibrosis; Heart; Heart Rate

2007
Aldosterone causes vasoconstriction in coronary arterioles of rats via angiotensin II type-1 receptor: influence of hypertension.
    European journal of pharmacology, 2007, Oct-31, Volume: 572, Issue:2-3

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Coronary Vessels; Endothe

2007
Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study.
    Clinical endocrinology, 2007, Volume: 67, Issue:6

    Topics: Adrenocorticotropic Hormone; Aged; Aldosterone; Alleles; Cortodoxone; Cytochrome P-450 CYP11B2; Fema

2007
The effect of diet on simvastatin and losartan enhancement of endothelial function.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2007, Volume: 29, Issue:5

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Diet;

2007
Tailored hormonal therapy in secretory adrenocortical cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:7

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Aldosterone; Alkalosis; Ang

2007
Is there an unrecognized epidemic of primary aldosteronism? Con.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:3

    Topics: Adrenal Gland Neoplasms; Aldosterone; Disease Outbreaks; Humans; Hyperaldosteronism; Hypertension; I

2007
Resistant hypertension: a methodological approach to diagnosis and treatment.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2007, Volume: 18, Issue:3

    Topics: Aldosterone; Diagnosis, Differential; Drug Resistance; Humans; Hyperaldosteronism; Hypertension; Pat

2007
A comparative study of plasma renin activity, aldosterone and atrial natriuretic hormone between normotensive and hypertensive people living at below sea level altitude (Jordan Valley) and those residing at moderate altitude above.
    Neuro endocrinology letters, 2007, Volume: 28, Issue:4

    Topics: Adult; Aged; Aldosterone; Altitude; Atrial Natriuretic Factor; Cross-Sectional Studies; Health Surve

2007
Associations between sympathetic activity, plasma concentrations of renin, aldosterone, and parathyroid hormone, and the degree of intractability of blood pressure control in modialysis patients.
    Journal of Korean medical science, 2007, Volume: 22, Issue:4

    Topics: Adult; Aged; Aldosterone; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Epinephrine

2007
Unexpected therapeutic response to spironolactone: a prospective debate on aldosterone and potassium ion in hypertension.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:5

    Topics: Aldosterone; Dose-Response Relationship, Drug; Humans; Hypertension; Potassium; Renin-Angiotensin Sy

2007
Determination of the aldosterone/renin ratio in 269 patients with adrenal incidentaloma.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2007, Volume: 115, Issue:8

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Blood Pressure; Female; Humans; Hyperten

2007
Increased plasma aldosterone-to-renin ratio is associated with impaired left ventricular longitudinal functional reserve in patients with uncomplicated hypertension.
    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2008, Volume: 21, Issue:3

    Topics: Aldosterone; Exercise Test; Female; Fractional Flow Reserve, Myocardial; Humans; Hypertension; Male;

2008
Antenatal and postnatal risk factors for neonatal hypertension and infant follow-up.
    Pediatric nephrology (Berlin, Germany), 2007, Volume: 22, Issue:12

    Topics: Aldosterone; Australia; Birth Weight; Blood Pressure; Body Height; Female; Follow-Up Studies; Gestat

2007
Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: role of oxidative stress.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:5

    Topics: Aldosterone; Animals; Antioxidants; Cyclic N-Oxides; Disease Models, Animal; Eplerenone; Hypertensio

2007
Sympathoadrenergic and metabolic factors are involved in ambulatory blood pressure rise in childhood obesity.
    Journal of human hypertension, 2008, Volume: 22, Issue:2

    Topics: Adolescent; Albuminuria; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Ma

2008
Resistant hypertension and aldosterone excess: new insights from ambulatory blood pressure monitoring.
    Journal of hypertension, 2007, Volume: 25, Issue:10

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Drug Resistance; Humans

2007
A possible association between primary aldosteronism and a lower beta-cell function.
    Journal of hypertension, 2007, Volume: 25, Issue:10

    Topics: Aged; Aldosterone; Blood Glucose; C-Peptide; Case-Control Studies; Cholesterol; Female; Humans; Hype

2007
Aldosterone excess and resistance to 24-h blood pressure control.
    Journal of hypertension, 2007, Volume: 25, Issue:10

    Topics: Adult; Age Factors; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Pressure Monit

2007
Long-term cardiac effects of adrenalectomy or mineralocorticoid antagonists in patients with primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Female; Follo

2007
Rapid cortisol assay during adrenal vein sampling in patients with primary aldosteronism.
    Clinical chemistry, 2007, Volume: 53, Issue:11

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Female; Humans; Hydrocortisone

2007
Insulin resistance and hyperinsulinemia are related to plasma aldosterone levels in hypertensive patients: response to Colussi et al.
    Diabetes care, 2007, Volume: 30, Issue:10

    Topics: Aldosterone; Humans; Hyperinsulinism; Hypertension; Insulin; Insulin Resistance; Reproducibility of

2007
Effects of aldosterone and angiotensin II receptor blockade on cardiac angiotensinogen and angiotensin-converting enzyme 2 expression in Dahl salt-sensitive hypertensive rats.
    American journal of hypertension, 2007, Volume: 20, Issue:10

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensinog

2007
Increased expression in calcitonin-like receptor induced by aldosterone in cerebral arteries from spontaneously hypertensive rats does not correlate with functional role of CGRP receptor.
    Regulatory peptides, 2008, Feb-07, Volume: 146, Issue:1-3

    Topics: Aldosterone; Animals; Calcitonin Receptor-Like Protein; Cerebral Arteries; Hypertension; Intracellul

2008
Absence of peroxisome proliferator-activated receptor-alpha abolishes hypertension and attenuates atherosclerosis in the Tsukuba hypertensive mouse.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Atherosclerosis; Blood Pressure; Cardiomegaly; Diet, Atherogen

2007
[Comparison of adrenal imaging and selective adrenal vein sampling in primary hyperaldosteronism].
    Deutsche medizinische Wochenschrift (1946), 2007, Volume: 132, Issue:46

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Female; Humans; Hydro

2007
[Hypokalemic hypertension cause by licorice abuse].
    Deutsche medizinische Wochenschrift (1946), 2007, Volume: 132, Issue:46

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Diagnosis, Differential; Female; Glycyrrhi

2007
Neuroendocrine profiling in inherited stress-induced arterial hypertension rat strain with stress-sensitive arterial hypertension.
    The Journal of endocrinology, 2007, Volume: 195, Issue:3

    Topics: Adrenal Cortex; Adrenal Medulla; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure;

2007
Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome.
    The Journal of physiology, 2008, Jan-15, Volume: 586, Issue:2

    Topics: Aldosterone; Animals; Colon; Disease Models, Animal; Epithelial Sodium Channels; Female; Hypertensio

2008
More fuel to the debate on the "epidemics of primary aldosteronism".
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Captopril; Humans; Hyperaldosteronism; Hyperte

2008
A not-so-modest proposal that a "modest" increase in aldosterone causes hypertension and more.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:1

    Topics: Aldosterone; Animals; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Mice; Renin; Sodium

2008
Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cytochrome P-450 CYP11B2; Female; Hyperaldoste

2008
The aldosterone to renin ratio in the evaluation of patients with incidentally detected adrenal masses.
    Endocrine, 2007, Volume: 32, Issue:2

    Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Case-Control Studies; Diagnosis, Differential; Fema

2007
Adrenocortical changes and arterial hypertension in lipoatrophic A-ZIP/F-1 mice.
    Molecular and cellular endocrinology, 2008, Jan-02, Volume: 280, Issue:1-2

    Topics: Adipokines; Adipose Tissue, White; Adrenal Cortex; Aldosterone; Animals; Blood Glucose; Blood Pressu

2008
Prospective evaluation and characteristics of patients with suspected primary hyperaldosteronism.
    The West Indian medical journal, 2007, Volume: 56, Issue:3

    Topics: Adult; Aldosterone; Body Mass Index; Female; Glucose Intolerance; Humans; Hyperaldosteronism; Hypert

2007
An additional child case of an aldosterone-producing adenoma with an atypical presentation of peripheral paralysis due to hypokalemia.
    Journal of endocrinological investigation, 2007, Volume: 30, Issue:10

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Aldosterone; Female; Humans; Hyperaldosteronism; Hyper

2007
Relation of dietary salt and aldosterone to urinary protein excretion in subjects with resistant hypertension.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:2

    Topics: Aged; Aldosterone; Circadian Rhythm; Cohort Studies; Female; Humans; Hypertension; Male; Middle Aged

2008
A novel adipokine CTRP1 stimulates aldosterone production.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Volume: 22, Issue:5

    Topics: Adipokines; Aldosterone; Angiotensin II; Animals; Calcium; Cytochrome P-450 CYP11B2; DNA-Binding Pro

2008
Plasma potassium level is associated with common genetic variation in the beta-subunit of the epithelial sodium channel.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:3

    Topics: Adult; Aldosterone; Alleles; Blood Pressure; DNA; Epithelial Sodium Channels; Female; Heterozygote;

2008
Cardiovascular outcomes in patients with primary aldosteronism after treatment.
    Archives of internal medicine, 2008, Jan-14, Volume: 168, Issue:1

    Topics: Adrenalectomy; Adult; Aged; Aldosterone; Cardiovascular Diseases; Female; Follow-Up Studies; Humans;

2008
Increased nocturnal sodium excretion in obstructive sleep apnoea. Relation to nocturnal change in diastolic blood pressure.
    Scandinavian journal of clinical and laboratory investigation, 2008, Volume: 68, Issue:1

    Topics: Adult; Age Factors; Aldosterone; Aquaporin 2; Arginine Vasopressin; Atrial Natriuretic Factor; Blood

2008
Diastolic dysfunction is associated with insulin resistance, but not with aldosterone level in normotensive offspring of hypertensive families.
    Cardiology, 2008, Volume: 111, Issue:1

    Topics: Adult; Aldosterone; Case-Control Studies; Female; Genetic Predisposition to Disease; Heart Failure,

2008
Letter regarding article by Hood et al, "The Spironolactone, Amiloride, Losartan, and Thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio".
    Circulation, 2008, Feb-05, Volume: 117, Issue:5

    Topics: Aldosterone; Amiloride; Antihypertensive Agents; Bendroflumethiazide; Cross-Over Studies; Double-Bli

2008
Aldosterone and hypertension in the cardiometabolic syndrome.
    Journal of clinical hypertension (Greenwich, Conn.), 2008, Volume: 10, Issue:2

    Topics: Aldosterone; Body Mass Index; Humans; Hyperaldosteronism; Hypertension; Metabolic Syndrome; Risk Fac

2008
RNAi inhibition of mineralocorticoid receptors prevents the development of cold-induced hypertension.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Cardiomegaly; Cold Temperature; Dependovirus; Dis

2008
Translational research goes both ways: lessons from clinical studies.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:4

    Topics: Aldosterone; Amino Acid Sequence; Antihypertensive Agents; Biomedical Research; Clinical Trials as T

2008
Urinary kallikrein and blood pressure--gender-different response to potassium supplementation in SHR. Role of aldosterone.
    Nephron. Physiology, 2008, Volume: 108, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Female; Hypertension; Kallikreins; Male; Potassium, Dietary; R

2008
Relationship between oxidative stress and essential hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:12

    Topics: Adult; Aldosterone; Ascorbic Acid; Blood Pressure; Cross-Sectional Studies; Dinoprost; Endothelin-1;

2007
Vascular remodeling and duration of hypertension predict outcome of adrenalectomy in primary aldosteronism patients.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Arteries; Blo

2008
Heart rate variability in white-coat hypertension.
    Blood pressure monitoring, 2008, Volume: 13, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensins; Arginine Vasopressin; Autonomic Nervous System; Blood Pressu

2008
Low renin hypertension (LRH): shades of John Laragh.
    Trends in endocrinology and metabolism: TEM, 2008, Volume: 19, Issue:3

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

2008
The antihypertensive effects of quercetin in a salt-sensitive model of hypertension.
    Journal of cardiovascular pharmacology, 2008, Volume: 51, Issue:3

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dimethyl Sulfoxide; Diseas

2008
The in vivo effects of Tulbhagia violacea on blood pressure in a salt-sensitive rat model.
    Journal of ethnopharmacology, 2008, May-08, Volume: 117, Issue:2

    Topics: Aldosterone; Animals; Blood Pressure; Heart Rate; Hypertension; Liliaceae; Male; Phytotherapy; Plant

2008
[Is there an unrecognized epidemic of primary aldosteronism? The Danish Society of Hypertension].
    Ugeskrift for laeger, 2008, Mar-17, Volume: 170, Issue:12

    Topics: Aldosterone; Denmark; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Prevalence; Renin

2008
Plasma and urine aldosterone to plasma renin activity ratio in the diagnosis of primary aldosteronism.
    Journal of hypertension, 2008, Volume: 26, Issue:5

    Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Predictive Value o

2008
Urinary aldosterone-to-active-renin ratio: a useful tool for predicting resolution of hypertension after adrenalectomy in patients with aldosterone-producing adenomas.
    American journal of hypertension, 2008, Volume: 21, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Age Factors; Aged; Aldosterone; Antihyperten

2008
Body mass index predicts plasma aldosterone concentrations in overweight-obese primary hypertensive patients.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:7

    Topics: Aldosterone; Body Mass Index; Female; Humans; Hypertension; Male; Middle Aged; Obesity; Overweight;

2008
High blood pressure arising from a defect in vascular function.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, May-06, Volume: 105, Issue:18

    Topics: Aldosterone; Animals; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinas

2008
High plasma aldosterone and low renin predict blood pressure increase and hypertension in middle-aged Caucasian populations.
    Journal of human hypertension, 2008, Volume: 22, Issue:8

    Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Female; Follow-Up Studies; France; Humans; Hyperten

2008
Significance of angiotensinogen gene haplotypes and genotypes combinations in hypertension.
    Journal of hypertension, 2008, Volume: 26, Issue:6

    Topics: Adult; Aldosterone; Angiotensinogen; Case-Control Studies; Female; Genotype; Haplotypes; Humans; Hyp

2008
Crosstalk between the heme oxygenase system, aldosterone, and phospholipase C in hypertension.
    Journal of hypertension, 2008, Volume: 26, Issue:6

    Topics: Aldosterone; Animals; Aorta; Blood Pressure; Calcium; Cyclic GMP; Cyclic GMP-Dependent Protein Kinas

2008
Upregulation of apical sodium-chloride cotransporter and basolateral chloride channels is responsible for the maintenance of salt-sensitive hypertension.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:2

    Topics: Aldosterone; Animals; Chloride Channels; Chloride-Bicarbonate Antiporters; Disease Models, Animal; E

2008
ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenocorticotropic Hormone; Aldosterone; Animals; Binding Sites; Blood Pr

2008
Effects of mannooligosaccharides from coffee mannan on blood pressure in Dahl salt-sensitive rats.
    Journal of nutritional science and vitaminology, 2008, Volume: 54, Issue:2

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Coffee; Diet; Disease Models, Animal; Hypertensio

2008
Central infusion of aldosterone synthase inhibitor prevents sympathetic hyperactivity and hypertension by central Na+ in Wistar rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Brain; Corticosterone; Cytochrome P-450 CYP11B

2008
A new form of congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Aldosterone;

1967
Heart failure in the elderly.
    Geriatrics, 1967, Volume: 22, Issue:3

    Topics: Aged; Aldosterone; Aminophylline; Digitalis; Diuretics; Heart Failure; Humans; Hypertension; Organom

1967
Independence of blood pressure and aldosterone secretion.
    The New England journal of medicine, 1967, Apr-06, Volume: 276, Issue:14

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Guanethidine; Humans; Hyperaldosteronism

1967
Bilateral adrenal hyperplasia as a cause of primary aldosteronism with hypertension, hypokalemia and suppressed renin activity.
    The American journal of medicine, 1967, Volume: 42, Issue:4

    Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenal Glands; Aldosterone; Blood Urea Nitrogen;

1967
The steroid content of adrenal adenomas and measurements of aldosterone production in patients with essential hypertension and primary aldosteronism.
    The Journal of clinical investigation, 1967, Volume: 46, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Corticosterone; Female; Humans; Hydrocor

1967
Salivary electrolytes, urea nitrogen, uric acid and salt taste thresholds in hypertension.
    Journal of oral therapeutics and pharmacology, 1967, Volume: 3, Issue:4

    Topics: Aldosterone; Chlorine; Citrates; Humans; Hypertension; Parotid Gland; Potassium; Saliva; Secretory R

1967
Hypertension and hypokalemic alkalosis associated with underproduction of aldosterone.
    Pediatrics, 1967, Volume: 39, Issue:6

    Topics: Adrenal Glands; Aldosterone; Alkalosis; Blood Pressure Determination; Child; Diagnosis, Differential

1967
Hypokalemia in the hypertensive patient, with observations on the incidence of primary aldosteronism.
    Annals of internal medicine, 1967, Volume: 66, Issue:6

    Topics: Aldosterone; Benzothiadiazines; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Potassium; Re

1967
Hypertension following subcutaneous and intraperitoneal injections of polyvinyl alcohol and the effect of aldosterone.
    Canadian journal of physiology and pharmacology, 1967, Volume: 45, Issue:1

    Topics: Alcohols; Aldosterone; Animals; Arteritis; Blood Pressure; Body Weight; Female; Hepatomegaly; Hypert

1967
Childhood primary aldosteronism with bilateral adrenocortical hyperplasia: plasma renin activity as an aid to diagnosis.
    The Journal of pediatrics, 1967, Volume: 71, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Child; Child, Preschool; Humans; Hyperaldosteronism; Hyp

1967
Primary aldosteronism: case report with plasma renin suppression.
    The Journal of the Indiana State Medical Association, 1967, Volume: 60, Issue:1

    Topics: Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension; Hypok

1967
Experimental hypertensive disease of pregnancy.
    Obstetrics and gynecology, 1967, Volume: 30, Issue:3

    Topics: Aldosterone; Angiography; Animals; Blood Pressure; Dogs; Female; Fetus; Hypertension; Kidney; Matern

1967
Effect of diazoxide on plasma renin activity in hypertensive patients.
    Annals of internal medicine, 1967, Volume: 67, Issue:4

    Topics: Aldosterone; Blood Glucose; Blood Pressure; Creatinine; Diazoxide; Diet; Humans; Hypertension; Natri

1967
[On the diagnosis of Conn's syndrome].
    Deutsche medizinische Wochenschrift (1946), 1967, Sep-01, Volume: 92, Issue:35

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Renin

1967
A quantitative gas-liquid chromatographic method for aldosterone in human urine.
    The Journal of laboratory and clinical medicine, 1967, Volume: 70, Issue:5

    Topics: Aldosterone; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Humans; Hyperaldosteronism

1967
[Electrolyte metabolism in hypertension].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1967, Jan-10, Volume: 56, Issue:1

    Topics: Adult; Aged; Aldosterone; Animals; Catecholamines; Diet; Female; Food; Humans; Hydrochlorothiazide;

1967
The comparative hypertensive activities of the acetates of D-aldosterone and deoxycorticosterone.
    Acta endocrinologica, 1967, Volume: 54, Issue:3

    Topics: Acetates; Aldosterone; Animals; Desoxycorticosterone; Female; Heart; Hypertension; Kidney; Myocardiu

1967
Oral contraceptives. Renin, aldosterone, and high blood pressure.
    JAMA, 1967, Sep-18, Volume: 201, Issue:12

    Topics: Adult; Aldosterone; Blood Pressure; Contraceptives, Oral; Female; Humans; Hypertension; Middle Aged;

1967
Pregnancy and primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:11

    Topics: Adult; Aldosterone; Carbon Dioxide; Chlorides; Female; Humans; Hyperaldosteronism; Hypertension; Pot

1967
[Renin-angiotensin-aldosterone system in hypertensive conditions].
    Deutsche medizinische Wochenschrift (1946), 1967, Oct-27, Volume: 92, Issue:43

    Topics: Adult; Aged; Aldosterone; Female; Fundus Oculi; Humans; Hypertension; Hypertension, Malignant; Hyper

1967
[Use of the method of determination of tetrahydroaldosterone in the study of clinical cases].
    Studii si cercetari de endocrinologie, 1967, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Child, Preschool; Female; Humans; Hyperaldosteronism; Hypertension;

1967
Renal effects of nitrendipine monotherapy in essential hypertension.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 7

    Topics: Adult; Aged; Aldosterone; Blood Volume; Calcium Channel Blockers; Cardiac Output; Epinephrine; Glome

1984
The calcium channel blocker nitrendipine in single- and multiple-agent antihypertensive regimens: preliminary report of a multicenter study.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 7

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Calcium Channel Blockers; Drug Therapy, Combi

1984
Clinical and experimental studies on human urinary angiotensin I-converting enzyme.
    Nihon Jinzo Gakkai shi, 1984, Volume: 26, Issue:3

    Topics: Aldosterone; Electrolytes; Humans; Hypertension; Kinetics; Molecular Weight; Peptidyl-Dipeptidase A;

1984
Hormonal and metabolic effects of angiotensin converting enzyme inhibitors. Possible differences between enalapril and captopril.
    The American journal of medicine, 1984, Aug-20, Volume: 77, Issue:2A

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dip

1984
Enalapril in treatment of hypertension with renal artery stenosis. Changes in blood pressure, renin, angiotensin I and II, renal function, and body composition.
    The American journal of medicine, 1984, Aug-20, Volume: 77, Issue:2A

    Topics: Administration, Oral; Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Body Compos

1984
Renal Na+-K+-ATPase in weanling and adult spontaneously hypertensive rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1984, Volume: 177, Issue:2

    Topics: Aldosterone; Animals; Hypertension; Kidney; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-A

1984
[Changes in responses of blood pressure and several hormones to infusions of angiotensin II and angiotensin III in patients with essential hypertension].
    Nihon Naibunpi Gakkai zasshi, 1984, May-20, Volume: 60, Issue:5

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Angiotensin III; Blood Pressure; Ca

1984
Influence of chronic renal failure on captopril pharmacokinetics and clinical and biological effects in hypertensive patients.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:5

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Femal

1984
Effects of prostacyclin on the responses of blood pressure and several hormones in normotensive and hypertensive subjects.
    Nihon Jinzo Gakkai shi, 1984, Volume: 26, Issue:9

    Topics: Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Epinephrine; Epoprostenol; Hormones; Human

1984
[Effect of ACTH on serum corticosteroid level in patients with hypertension].
    Terapevticheskii arkhiv, 1984, Volume: 56, Issue:12

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hyp

1984
Plasma enalapril levels and hormonal effects after short- and long-term administration in essential hypertension.
    British journal of clinical pharmacology, 1984, Volume: 18 Suppl 2

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bloo

1984
Altered corticosteroid control of the erythrocyte sodium-potassium pump in the spontaneously hypertensive rat.
    Journal of hypertension, 1983, Volume: 1, Issue:4

    Topics: Adenosine Triphosphatases; Adrenal Cortex Hormones; Adrenalectomy; Aldosterone; Animals; Dexamethaso

1983
Volume control and altered renal and adrenal responsiveness to angiotensin in essential hypertension: implications for treatment with converting enzyme inhibition.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1983, Volume: 1, Issue:1

    Topics: Adrenal Glands; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bloo

1983
Physiological effects of short-term treatment with enalapril in hypertensive patients.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1983, Volume: 1, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Dose-Response Relationship, Drug; Enalapril; Epinephrine; Female

1983
Clinical pharmacology of enalapril.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:2

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biological Ava

1984
Converting enzyme inhibitors normalize the reduced adrenal responsiveness to angiotensin II in essential hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:2

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressur

1984
Beta-adrenergic regulation of circadian rhythmicity of the renin-angiotensin-aldosterone system in five subtypes of essential hypertension.
    Giornale italiano di cardiologia, 1980, Volume: 10, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Circadian Rhythm; Femal

1980
Low-dose diuretic and beta adrenoceptor blocker in essential hypertension.
    Clinical pharmacology and therapeutics, 1980, Volume: 28, Issue:2

    Topics: Adrenergic beta-Antagonists; Aldosterone; Analysis of Variance; Black People; Blood Pressure; Diuret

1980
Angiotensin II blockade during combined thiazide-beta-blocker treatment.
    Scandinavian journal of clinical and laboratory investigation, 1980, Volume: 40, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Drug Interactions; Female; Humans;

1980
[Neurohumoral regulation problems and the pathogenesis of hypertension].
    Kardiologiia, 1980, Volume: 20, Issue:9

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Blood Pressure; Homeostasis; Humans; Hypertension; Neur

1980
Prizidilol, an antihypertensive with precapillary vasodilator and beta-adrenoceptor blocking actions, in primary hypertension.
    Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Antihypertensive Agents; Drug Evaluation; Fem

1981
Antihypertensive effect of the new oral angiotensin converting enzyme inhibitor "MK-421".
    Lancet (London, England), 1981, Sep-12, Volume: 2, Issue:8246

    Topics: Administration, Oral; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibi

1981
Net influx and efflux of 22Na in erythrocytes from normotensive offspring of patients with essential hypertension.
    Acta medica Scandinavica, 1981, Volume: 210, Issue:1-2

    Topics: Adult; Aldosterone; Biological Transport; Erythrocytes; Female; gamma-Glutamyltransferase; Humans; H

1981
Neurohumoral response to hospitalization in hypertensive patients.
    Clinical science (London, England : 1979), 1981, Volume: 61 Suppl 7

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Epinephrine; Hospitalization; Humans; Hypertension; Middle

1981
Biochemistry and pharmacology of hypertension.
    Biochemical Society transactions, 1982, Volume: 10, Issue:3

    Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Brain; Homeostasis; Humans; Hypertension;

1982
Prizidilol (SK & F 92657), a new vasodilator with beta-blocking properties in the treatment of essential hypertension.
    European journal of clinical pharmacology, 1982, Volume: 23, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Pressure; Female; Heart Rate; Humans; H

1982
[Mineralocorticoid function of the adrenal glands in adolescents with primary arterial hypertension before and after treatment with beta-blocking agents].
    Kardiologiia, 1983, Volume: 23, Issue:4

    Topics: Administration, Oral; Adolescent; Adrenal Cortex; Adrenergic beta-Antagonists; Aerosols; Aldosterone

1983
The role of prostaglandins in the regulation of blood pressure with special reference to vascular reactivity.
    Japanese circulation journal, 1984, Volume: 48, Issue:2

    Topics: Adult; Aldosterone; Alprostadil; Animals; Blood Pressure; Humans; Hypertension; Indomethacin; Male;

1984
[Etiological studies of hypertension. A Renin-angiotension-aldosterone system].
    Nihon rinsho. Japanese journal of clinical medicine, 1984, Volume: 42, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Humans; Hypertension; Middle Aged; Renin; Renin-Ang

1984
Treatment of drug-resistant hypertension with minoxidil or angiotensin-converting enzyme inhibitor: blood pressure, renin, aldosterone, and electrolyte responses.
    Journal of cardiovascular pharmacology, 1980, Volume: 2 Suppl 2

    Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Captopril; Creatinine; Drug Resistance; Female; Hum

1980
Increased aldosterone metabolic clearance in hypertensive patients treated with minoxidil: an effect of greater hepatic perfusion.
    Journal of cardiovascular pharmacology, 1980, Volume: 2 Suppl 2

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Diuretics; Humans; Hypertension; Indocyanine Green; Liver;

1980
Angiotensin-converting enzyme inhibitors.
    American family physician, 1980, Volume: 22, Issue:5

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Heart Failure; Hum

1980
Altered blood pressure and renin responses to converting enzyme inhibition after aprotinin-induced kallikrein-kinin-system blockade.
    Clinical science (London, England : 1979), 1980, Volume: 59 Suppl 6

    Topics: Aldosterone; Angiotensin II; Aprotinin; Blood Pressure; Captopril; Humans; Hypertension; Peptidyl-Di

1980
[Aldosterone content of the blood in ischemic heart disease under antireticular cytotoxic serum treatment].
    Vrachebnoe delo, 1982, Issue:2

    Topics: Adult; Aldosterone; Coronary Disease; Female; Humans; Hypertension; Immune Sera; Immunization, Passi

1982
Relation of blood pressure and body sodium content during sodium depletion in normal and hypertensive subjects.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 1

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Diuretics; Humans; Hype

1984
Distribution of extracellular fluid over the intra- and extravascular space in hypertensive patients.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 1

    Topics: Adenoma; Adult; Aldosterone; Blood Pressure; Blood Volume; Cardiac Output; Extracellular Space; Huma

1984
Forearm vasoconstrictor response to ouabain: studies in patients with mild and moderate essential hypertension.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 1

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Epinephrine; Forearm; Humans; Hypertension; Male; Middle A

1984
[A simple diagnostic test for primary hyperaldosteronism].
    Presse medicale (Paris, France : 1983), 1983, May-28, Volume: 12, Issue:23

    Topics: Adrenal Glands; Adult; Aldosterone; Captopril; Humans; Hyperaldosteronism; Hyperplasia; Hypertension

1983
The characteristics of renal mineralocorticoid receptors in glycyrrhizinic acid or deoxycorticosterone-induced hypertensive rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1984, Volume: 6, Issue:9

    Topics: Aldosterone; Animals; Blood Pressure; Cytosol; Desoxycorticosterone; Glycyrrhetinic Acid; Glycyrrhiz

1984
[Binding of aldosterone to its receptors along the nephron of the normal and spontaneously hypertensive rat].
    Archives des maladies du coeur et des vaisseaux, 1984, Volume: 77, Issue:11

    Topics: Aldosterone; Animals; Autoradiography; Female; Hypertension; Nephrons; Rats; Rats, Inbred SHR; Rats,

1984
Endocrine and cardiovascular influences of converting enzyme inhibition with SQ 14225 in hypertensive patients in the supine position and during head-up tilt before and after sodium depletion.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:4

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Epinephrine

1980
[The long term effect of the oral converting enzyme inhibitor captopril in hypertensive patients (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1980, Mar-20, Volume: 56, Issue:3

    Topics: Administration, Oral; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Catecholamin

1980
In vitro steroidogenic properties of a new hypertension-producing compound isolated from normal human urine.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:1

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Cats; Cyclic AMP;

1980
[Clinical experience with an oral angiotensin I-converting enzyme inhibitor in hypertensive patients: effects on blood pressure and the renin-aldosterone system by a single dose (author's transl)].
    Nihon Jinzo Gakkai shi, 1980, Volume: 22, Issue:1

    Topics: Administration, Oral; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure;

1980
Chronic ACTH administration and the development of hypertension in rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1980, Volume: 163, Issue:4

    Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure; Blood Volume; Corticosterone; Des

1980
[Effect of angiotensin converting enzyme inhibitor (SQ 14225) on renin-angiotesin sytem and haemodynamics (author's transl)].
    Horumon to rinsho. Clinical endocrinology, 1980, Volume: 28, Issue:5

    Topics: Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Captopril; Hemodynamics; Human

1980
Renin-angiotensin-aldosterone system.
    European journal of clinical pharmacology, 1980, Volume: 18, Issue:1

    Topics: Aging; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Humans

1980
Dose response in captopril therapy of hypertension.
    Clinical pharmacology and therapeutics, 1980, Volume: 28, Issue:3

    Topics: Adult; Aldosterone; Angiotensins; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Femal

1980
Endocrine profile in the long-term phase of converting-enzyme inhibition.
    Clinical pharmacology and therapeutics, 1980, Volume: 28, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diet, Sodiu

1980
Primary aldosteronism due to unilateral adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:5

    Topics: Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldosterone; Blood Pressur

1980
Aldosterone-induced hypertension: effects of a kininase inhibitor.
    Clinical and experimental hypertension, 1980, Volume: 2, Issue:5

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Female; H

1980
Sodium-potassium-dependent ATPase activity in erythrocyte ghosts of patients with primary and secondary hypertension.
    Clinical science (London, England : 1979), 1980, Volume: 59 Suppl 6

    Topics: Adult; Aldosterone; Cushing Syndrome; Erythrocyte Membrane; Erythrocytes; Female; Humans; Hydrocorti

1980
[The long term effects of the oral converting enzyme inhibitor, captopril in hypertensive patients--the endocrinological study of its hypotensive mechanism (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1980, Oct-20, Volume: 56, Issue:10

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Catecholami

1980
Studies on the mechanism of "exaggerated natriuresis" in essential hypertension.
    Japanese circulation journal, 1981, Volume: 45, Issue:1

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Diuresis; Glomerul

1981
Aldosterone response to prolonged ACTH infusion in juvenile hypertension.
    Pediatric research, 1980, Volume: 14, Issue:9

    Topics: Adolescent; Adrenocorticotropic Hormone; Aldosterone; Child; Humans; Hypertension; Potassium; Renin;

1980
[Captopril in the treatment of essential hypertension (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Sep-19, Volume: 105, Issue:38

    Topics: Adult; Aldosterone; Anemia; Captopril; Humans; Hypertension; Middle Aged; Peptidyl-Dipeptidase A; Po

1980
Plasma aldosterone and corticosterone responses to adrenocorticotropin, angiotensin, potassium, and stress in spontaneously hypertensive rats.
    Endocrinology, 1981, Volume: 108, Issue:4

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Corticosterone; Hypertension; Mal

1981
Captopril in various forms of severe therapy-resistant hypertension.
    Klinische Wochenschrift, 1981, Jan-15, Volume: 59, Issue:2

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Captopril; Female; Heart Rate; Humans; Hypert

1981
Effects of a single administration of captopril on hemodynamics and serum angiotensin converting enzyme activity, plasma renin activity and plasma aldosterone concentration in hypertensive patients.
    Japanese circulation journal, 1981, Volume: 45, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Cardiac Output; Female; Heart Rate; Hemodynamics; Hum

1981
Intra-erythrocyte sodium and (Na+,K+-activated)-ATPase concentration and urinary aldosterone excretion in spontaneously hypertensive rats.
    Clinical science (London, England : 1979), 1981, Volume: 60, Issue:2

    Topics: Adenosine Triphosphate; Aldosterone; Animals; Erythrocytes; Hypertension; Male; Potassium; Rats; Sod

1981
[Behavior of aldosterone and plasma renin activity after ACTH administration and insulin-induced hypoglycemia in patients with essential arterial hypertension].
    Minerva medica, 1981, Mar-10, Volume: 72, Issue:9

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Glucose; Humans; Hydrocortisone; Hypertension

1981
Effect of propranolol therapy on aldosterone responses to angiotensin II and adrenocorticotropic hormone in essential hypertension.
    Clinical science (London, England : 1979), 1981, Volume: 61, Issue:1

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Humans; Hypertension; Male; Middle Aged; P

1981
Overproduction of sodium-retaining steroids by the zona glomerulosa is adrenocorticotropin-dependent and mediates hypertension in dexamethasone-suppressible aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 53, Issue:2

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Aminoglutethimide; Child, Preschool

1981
Alterations in aldosterone biosynthesis in essential hypertensives.
    Circulation research, 1981, Volume: 49, Issue:3

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Humans; Hypertension; Middle Aged;

1981
Hormonal responses to long-term converting enzyme inhibition in hypertensive patients.
    Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril;

1981
[Changes in blood viscosity concomitant with prazosin therapy in patients with essential arterial hypertension].
    Cardiology, 1980, Volume: 66 Suppl 2

    Topics: Adult; Aldosterone; Blood Pressure; Blood Viscosity; Creatinine; Female; Heart Rate; Humans; Hyperte

1980
[Lecture: the interrelation between endocrinology and clinical internal medicine (author's transl)].
    Zhonghua nei ke za zhi, 1981, Volume: 20, Issue:5

    Topics: Adult; Aldosterone; Angiotensins; Cyclic AMP; Cyclic GMP; Endocrine Glands; Female; Humans; Hyperten

1981
Hypertension, hypokalemia and hypoaldosteronism with suppressed renin: a clinical study of a patient with Liddle's syndrome.
    Endocrinologia japonica, 1981, Volume: 28, Issue:3

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Biological Transport; Diagnosis, Differential; Fema

1981
Decreased adrenal responsiveness to angiotensin II: a defect present in spontaneously hypertensive rats. A possible model of human essential hypertension.
    The Journal of clinical investigation, 1982, Volume: 69, Issue:1

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Corticosterone; Disease Models, Animal; Female

1982
Pituitary - adrenocortical function in patients during treatment with the angiotensin-converting enzyme inhibitor captopril.
    Clinical endocrinology, 1981, Volume: 15, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Captopril; Female; Humans; Hydrocortisone; Hyperten

1981
Two cases of low-renin hypertension thought to be due to excessive secretion of unknown mineralocorticoid.
    Japanese circulation journal, 1982, Volume: 46, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood P

1982
Dexamethasone suppressible hyperaldosteronism in a child with nephrosclerosis.
    Acta endocrinologica, 1982, Volume: 99, Issue:2

    Topics: Adrenocorticotropic Hormone; Aldosterone; Child; Dexamethasone; Glomerulonephritis; Humans; Hyperald

1982
Converting enzyme inhibition with captopril in patients with primary hyperaldosteronism.
    Clinical pharmacology and therapeutics, 1982, Volume: 31, Issue:3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Drug Therapy, Comb

1982
Effects of angiotensin I converting enzyme inhibitor (SQ 14,225) on the responses of blood pressure and steroid hormone to angiotensin II and ACTH infusion in hypertensive subjects.
    Japanese circulation journal, 1982, Volume: 46, Issue:3

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopr

1982
Prediction of sustained antihypertensive efficacy of chronic captopril therapy: relationships to immediate blood pressure response and control plasma renin activity.
    American heart journal, 1982, Volume: 103, Issue:3

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood P

1982
Angiotensin-converting enzyme inhibition, catecholamines and hemodynamics in essential hypertension.
    The American journal of cardiology, 1982, Apr-21, Volume: 49, Issue:6

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Epinephrine

1982
Acute and chronic effects of the angiotensin-converting enzyme inhibitor captopril in severe hypertension.
    The American journal of cardiology, 1982, Apr-21, Volume: 49, Issue:6

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Creatinine; Dose-R

1982
Humoral and hemodynamic effects of increasing doses of captopril in patients with essential hypertension.
    The American journal of cardiology, 1982, Apr-21, Volume: 49, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Female; Hemodynamic

1982
SA446, a new orally active converting enzyme inhibitor: antihypertensive action and comparison with captopril in stroke-prone spontaneously hypersensitive rats.
    European journal of pharmacology, 1982, Mar-26, Volume: 78, Issue:4

    Topics: 3-Mercaptopropionic Acid; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypert

1982
The role of steroids in human essential hypertension.
    Biochemical pharmacology, 1982, Mar-15, Volume: 31, Issue:6

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Desoxycorticoster

1982
Effects of enalapril, a new converting enzyme inhibitor, in hypertension.
    Clinical pharmacology and therapeutics, 1982, Volume: 32, Issue:1

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood P

1982
Response of plasma ACTH and adrenocortical hormones to potassium loading in essential hypertension.
    Japanese circulation journal, 1982, Volume: 46, Issue:4

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldosterone; Desoxycorticosterone; Grow

1982
19-nor-deoxycorticosterone excretion in healthy and hypertensive subjects.
    Transactions of the Association of American Physicians, 1981, Volume: 94

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Desoxycorticosterone; Electrolytes; Female; Humans;

1981
[Role of hormonal factors in the development of arterial hypertension in obesity].
    Sovetskaia meditsina, 1982, Issue:5

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Humans; Hypertension; Obesity; Renin; Secretory Rat

1982
17 alpha-hydroxylase deficiency syndrome associated with bilateral streak gonads and impaired development of Müllerian ducts derivatives. Report of a case.
    Acta endocrinologica, 1982, Volume: 100, Issue:1

    Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aldosterone; Amenorrhea; C

1982
Exchangeable and total body sodium and potassium in various hypertensive syndromes.
    Contributions to nephrology, 1982, Volume: 30

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Humans; Hydrocortisone; Hyperaldosteronism

1982
19-hydroxyandrostenedione, a new amplifier of the action of aldosterone, in low renin essential hypertension.
    Japanese journal of medicine, 1982, Volume: 21, Issue:2

    Topics: Addison Disease; Adrenocorticotropic Hormone; Aldosterone; Androstenedione; Cushing Syndrome; Female

1982
Increased excretion of 18-hydroxycorticosterone in patients with adrenal adenomas and hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Aldo

1982
Aldosterone response to antihypertensive treatment.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Atenolol; Blood Pressure; Dipepti

1982
Suppression of adrenal mineralocorticoid production in prehypertensive young adult men.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:1

    Topics: 18-Hydroxycorticosterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldosterone;

1983
Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension.
    American heart journal, 1982, Volume: 104, Issue:6

    Topics: Adult; Age Factors; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Calcium; Heart Rate;

1982
Specificity of the alteration in aldosterone biosynthesis in the spontaneously hypertensive rat.
    Endocrinology, 1983, Volume: 112, Issue:2

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Corticosterone; Diet, Sodium-Rest

1983
Participation of the renin system in treatment-resistant hypertension as measured by acute blockade of the angiotensin converting enzyme.
    American journal of nephrology, 1982, Volume: 2, Issue:1

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Humans; Hyp

1982
Metabolic and blood pressure responses to hydrocortisone in the syndrome of apparent mineralocorticoid excess.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:2

    Topics: Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Child; Female; Humans; Hydrocortisone; Hyd

1983
Cardiovascular, humoral, and renal effects of phenoxybenzamine in hypertension.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1983, Volume: 2, Issue:5

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Cardiovascular System; Furosemide; Humans; Hypertens

1983
Adrenocortical response to corticotropin is inhibited by gamma 3-MSH antisera in normotensive and spontaneously hypertensive rats.
    Biochemical and biophysical research communications, 1983, Jan-27, Volume: 110, Issue:2

    Topics: 18-Hydroxycorticosterone; Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Animals; Antibod

1983
Volume hormones and blood pressure.
    Annals of internal medicine, 1983, Volume: 98, Issue:5 Pt 2

    Topics: Aldosterone; Animals; Arginine Vasopressin; Blood Pressure; Blood Volume; Female; Heart Atria; Human

1983
Effects of a new angiotensin-converting enzyme inhibitor, MK 421, in normal men and patients.
    Endocrinologia japonica, 1982, Volume: 29, Issue:5

    Topics: Adult; Aldosterone; Angiotensin I; Antihypertensive Agents; Bartter Syndrome; Blood Pressure; Dipept

1982
Influence of food on the clinical effect of angiotensin I converting enzyme inhibitor (SQ 14,225).
    The Tohoku journal of experimental medicine, 1983, Volume: 139, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Drug Administration Schedule; Female; Food; Humans; H

1983
[Relation between hormonal and hemodynamics indices during emotional stress in healthy individuals and in hypertensive patients].
    Kardiologiia, 1983, Volume: 23, Issue:4

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Hemodynamics; Humans; Hydro

1983
Aldosterone suppression with dopamine infusion in low-renin hypertension.
    The Journal of clinical investigation, 1983, Volume: 72, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; B

1983
10. Hypertension. A comparison of the effects of angiotensin II infusion and variations in salt intake on plasma aldosterone levels in normal subjects, patients with essential hypertension and patients with hyperaldosteronism.
    Journal of steroid biochemistry, 1983, Volume: 19, Issue:1A

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Corticosterone; Desoxycorticosterone; Dexa

1983
[Corticotropin studies in essential hypertension].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1983, Aug-01, Volume: 38, Issue:15

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hypertension; Male;

1983
Angiotensin converting enzyme inhibition reveals an important role for the renin system in the control of normal and high blood pressure in man.
    Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:7-8

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captop

1983
The role of corticosteroids in the regulation of myocardial Na, K-ATPase in normotensive and spontaneously hypertensive rats.
    Clinical science (London, England : 1979), 1984, Volume: 66, Issue:4

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Aldosterone; Animals; Blood Pressure; Body Weight; Dexametha

1984
[Use of angiotensin converting enzyme inhibitor captopril and peripheral vasodilator minoxidil in the treatment of patients with stable and malignant arterial hypertension].
    Kardiologiia, 1983, Volume: 23, Issue:12

    Topics: Adolescent; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril;

1983
Importance of the adrenal cortex for development and maintenance of hypertension in spontaneously hypertensive rats.
    Acta endocrinologica, 1984, Volume: 105, Issue:3

    Topics: Adrenal Cortex; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Animals; Be

1984
Androgen modulation of adrenal angiotensin receptors.
    Science (New York, N.Y.), 1984, Jun-01, Volume: 224, Issue:4652

    Topics: Adrenal Cortex; Aldosterone; Androgens; Angiotensin II; Angiotensin III; Animals; Cattle; Cell Membr

1984
Renin, aldosterone, and serum-converting enzyme activity during normal and hypertensive pregnancy.
    Gynecologic and obstetric investigation, 1984, Volume: 17, Issue:5

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy Compl

1984
19-nor-deoxycorticosterone excretion in primary aldosteronism and low renin hypertension.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Desoxycorticosterone; Fe

1983
Environmental and physiological characteristics in adolescents genetically predisposed to hypertension.
    Japanese circulation journal, 1983, Volume: 47, Issue:2

    Topics: Adolescent; Aldosterone; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Kallikreins; Kidn

1983
6 beta-Hydroxyandrostenedione: evidence for a new hypertensinogenic agent.
    Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:1

    Topics: Aldosterone; Androstenedione; Angiotensinogen; Angiotensins; Animals; Corticosterone; Hypertension;

1983
Effect of captopril on blood pressure and on the renin-angiotensin-aldosterone system in coarctation of the aorta.
    Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Aortic Coarctation; Blood Pressure; Captopril; Dose-Response Relatio

1983
Urinary prostaglandin E2 and kallikrein excretion in glucocorticoid hypertension in rats.
    Clinical science (London, England : 1979), 1983, Volume: 65, Issue:1

    Topics: Aldosterone; Animals; Blood Pressure; Captopril; Dexamethasone; Dinoprostone; Hypertension; Kallikre

1983
[Effects of excessive salt-loading on blood pressure, plasma norepinephrine concentration, plasma renin activity, plasma aldosterone concentration and urinary aldosterone excretion in patients with essential hypertension and normotensive subjects].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1983, Jan-10, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nor

1983
Role of the aldosterone system in the salt-sensitivity of patients with benign essential hypertension.
    Japanese heart journal, 1983, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hypertensio

1983
Changes in renal function induced by endralazine, a new antihypertensive drug.
    European journal of clinical pharmacology, 1983, Volume: 24, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Female; Glomerular Filtration Rate; Heart Rate

1983
[Low renin variant of hypertension: functional relations of the renin-aldosterone pressor system].
    Kardiologiia, 1983, Volume: 23, Issue:4

    Topics: Aldosterone; Diuresis; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Ang

1983
Renin and aldosterone concentrations in pregnant essential hypertensives - a prospective study.
    Clinical and experimental hypertension. Part B, Hypertension in pregnancy, 1983, Volume: 2, Issue:2

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Labetalol; Methyldopa; Potassium; Pregnancy; Pregn

1983
Effects of intravenous endralazine in essential hypertension.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:1

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Epinephrine; Female; Humans; Hypertensi

1983
Ketamine hypertension and the renin-angiotensin system.
    Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:6

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Ketamine; Renin; R

1983
Increased urinary kallikrein excretion in young borderline hypertensive patients.
    Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:6

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Kallikreins; Male; Renal Circulation; Renin; Sodiu

1983
[Studies on the pathogenesis of arterial hypertension in acromegaly. I. The renin-angiotensin-aldosterone system].
    Polskie Archiwum Medycyny Wewnetrznej, 1983, Volume: 69, Issue:2

    Topics: Acromegaly; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Growth Hormone; Humans; Hydr

1983
Adrenal cortical carcinoma: an unusual cause of hyperaldosteronism.
    Canadian Medical Association journal, 1983, Oct-01, Volume: 129, Issue:7

    Topics: Adrenal Cortex Neoplasms; Adult; Aldosterone; Carcinoma; Humans; Hyperaldosteronism; Hypertension; H

1983
Effects of penbutolol and metoprolol on blood pressure, plasma catecholamines and renin activity in hypertensive patients.
    European heart journal, 1983, Volume: 4 Suppl D

    Topics: Aldosterone; Blood Pressure; Catecholamines; Female; Humans; Hypertension; Male; Metoprolol; Penbuto

1983
Sympathetic nerve and hormonal responses to a single dose of nifedipine in patients with essential hypertension and normal subjects: comparison among renin-subgroups.
    Hiroshima journal of medical sciences, 1983, Volume: 32, Issue:2

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Female; Hormones; Humans; Hypertension; Male; Middle Aged;

1983
Single dose captopril as a diagnostic test for primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Captopril; Diagnosis, Differential; Fema

1983
[The pressor and adrenal responses to angiotensin II in patients with normoreninemic essential hypertension--the influence of sodium intake and captopril].
    Nihon Jinzo Gakkai shi, 1983, Volume: 25, Issue:2

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Captopril; Diet, Sodium-Restricted; Female; Humans; Hyp

1983
[A new diagnostic test for primary tumoral hyperaldosteronism].
    Annales de medecine interne, 1983, Volume: 134, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Captopril; Humans; Hyperaldost

1983
[Relation existing between the kallikrein-kinin and renin-angiotensin-aldosterone systems].
    La Clinica terapeutica, 1983, Aug-15, Volume: 106, Issue:3

    Topics: Aldosterone; Humans; Hypertension; Kallikreins; Kinins; Liver Cirrhosis; Renin; Renin-Angiotensin Sy

1983
Effect of captopril on the renin-angiotensin system in hypertensive children.
    The Journal of pediatrics, 1983, Volume: 103, Issue:5

    Topics: Adolescent; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Child; Humans; Hypertension; Prol

1983
Defect in the sodium-modulated tissue responsiveness to angiotensin II in essential hypertension.
    The Journal of clinical investigation, 1983, Volume: 72, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Humans; Hypertension; Kinet

1983
Renin-angiotensin system in normotensive and hypertensive patients with progressive systemic sclerosis: hyporesponsiveness of renin during captopril test.
    Postgraduate medical journal, 1983, Volume: 59 Suppl 3

    Topics: Adult; Aged; Aldosterone; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Proline; Renin

1983
[Urinary kallikrein and other vasoactive substances in patients with primary aldosteronism and essential hypertension].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1983, Volume: 74, Issue:6

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Kallikreins; Male; Middle Aged

1983
Plasma catecholamines and autonomic nervous system function in patients with early renal insufficiency and hypertension: effect of clonidine.
    Nephron, 1984, Volume: 36, Issue:1

    Topics: Adult; Aged; Aldosterone; Clonidine; Female; Hemodynamics; Humans; Hypertension; Kidney Diseases; Ma

1984
Plasma renin activity, blood uric acid and plasma volume in pregnancy-induced hypertension.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1983, Volume: 20

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Plasma Volume; Pregnancy; Pregnancy Complications,

1983
Fatal, low renin hypertension associated with a disturbance of cortisol metabolism.
    Archives of disease in childhood, 1983, Volume: 58, Issue:12

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Humans; Hydrocortisone; Hydroxysteroid Dehydroge

1983
Captopril enhances vascular and adrenal responsiveness to angiotensin II in essential hypertension.
    Clinical science (London, England : 1979), 1984, Volume: 66, Issue:3

    Topics: Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Humans;

1984
[Acute antihypertensive effect of captopril in hypertensive patients: with special reference to kallikrein-kinin system].
    Nihon Naibunpi Gakkai zasshi, 1983, Oct-20, Volume: 59, Issue:10

    Topics: Adult; Aldosterone; Blood Pressure; Bradykinin; Captopril; Female; Humans; Hyperaldosteronism; Hyper

1983
[Relation between dopamine secretion and saltsensitivity in essential hypertension].
    Nihon Naibunpi Gakkai zasshi, 1983, Oct-20, Volume: 59, Issue:10

    Topics: Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Dopamine; Epinephrine; Hematocrit; Huma

1983
Acute arterial fibrinoid deposition and ischaemic parenchymal damage of the kidney. Pathogenic factors in the development of malignant hypertension.
    The Journal of pathology, 1983, Volume: 141, Issue:2

    Topics: Aldosterone; Animals; Arteries; Blood Urea Nitrogen; Corticosterone; Hypertension; Hypertension, Mal

1983
The relationship of aldosterone to mild essential hypertension.
    Research communications in chemical pathology and pharmacology, 1983, Volume: 42, Issue:3

    Topics: Adult; Aging; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Renin; Renin-

1983
Unilateral hypersecretion of aldosterone associated with adrenal hyperplasia as a cause of primary aldosteronism.
    Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:10

    Topics: Adrenal Cortex; Adrenal Glands; Adrenalectomy; Aldosterone; Female; Furosemide; Humans; Hyperaldoste

1983
A comparison of biological effects of three angiotensin II antagonists in sodium depleted hypertensive patients.
    Medical journal of Osaka University, 1983, Volume: 34, Issue:1-2

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypert

1983
Effects of diuretic therapy in low-, normal- and high-renin isolated systolic systemic hypertension.
    The American journal of cardiology, 1984, Mar-01, Volume: 53, Issue:6

    Topics: Adult; Aged; Aldosterone; Diuretics; Humans; Hypertension; Middle Aged; Prognosis; Renin; Sodium

1984
Effects of long-term prazosin therapy on lipoprotein metabolism in hypertensive patients.
    The American journal of medicine, 1984, Feb-27, Volume: 76, Issue:2A

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Lipoproteins; Male; Middle A

1984
Effect of metoprolol on 24-hour urinary excretion of adrenal steroids and kallikrein in patients with essential hypertension.
    British journal of pharmacology, 1984, Volume: 81, Issue:2

    Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Adult; Aldosteron

1984
Cation transport of red blood cells from hypertensive patients in Japan.
    Japanese heart journal, 1983, Volume: 24, Issue:6

    Topics: Adolescent; Adult; Aged; Aldosterone; Biological Transport; Erythrocytes; Female; Humans; Hypertensi

1983
Elevation of plasma renin activity during pregnancy and rupture of a dissecting aortic aneurysm in a patient with primary aldosteronism.
    Japanese heart journal, 1983, Volume: 24, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Aortic Dissection; Aortic Rupture; Female; Hu

1983
Urinary kallikrein activity (esterase activity), plasma renin activity, and urinary aldosterone excretion in kidney transplantation patients.
    Transplantation proceedings, 1983, Volume: 15, Issue:4

    Topics: Adult; Aldosterone; Esterases; Female; Humans; Hypertension; Kallikreins; Kidney Transplantation; Ma

1983
Effects of timolol on blood pressure, systemic hemodynamics, plasma renin activity, and glomerular filtration rate in patients with essential hypertension.
    International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension;

1984
[The role of sodium and potassium in borderline hypertension].
    Nihon Jinzo Gakkai shi, 1983, Volume: 25, Issue:11

    Topics: Adult; Aldosterone; Blood Pressure; Cardiac Output; Heart Rate; Humans; Hypertension; Male; Potassiu

1983
[Differential aspects of the dynamics of the renin-angiotensin-aldosterone system in obesity with and without hypertension and in essential arterial hypertension].
    Quaderni Sclavo di diagnostica clinica e di laboratorio, 1983, Volume: 19, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Female; Humans; Hypertension; Male; Middle Aged; Ob

1983
[Treatment of arterial hypertension patients depending on renin activity].
    Vrachebnoe delo, 1984, Issue:2

    Topics: Aldosterone; Antihypertensive Agents; Diuretics; Humans; Hypertension; Kallikreins; Prekallikrein; R

1984
An exaggerated natriuretic response to hypertonic saline infusion in the stage II (who stage classification) essential hypertensive patients.
    Clinical and experimental hypertension. Part A, Theory and practice, 1984, Volume: 6, Issue:3

    Topics: Adult; Aldosterone; Diuresis; Extracellular Space; Female; Humans; Hypertension; Male; Middle Aged;

1984
[Plasma renin activity and plasma aldosterone change in diabetic nephropathy].
    Zhonghua nei ke za zhi, 1983, Volume: 22, Issue:12

    Topics: Adult; Aldosterone; Diabetic Nephropathies; Female; Humans; Hypertension; Male; Middle Aged; Posture

1983
Urinary kallikrein excretion in patients with primary aldosteronism: differentiation of adrenal adenoma from idiopathic adrenal hyperplasia.
    Urologia internationalis, 1984, Volume: 39, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Diagnosis, Differential; Diet,

1984
Thiazide-induced potassium loss not prevented by beta blockade.
    Clinical pharmacology and therapeutics, 1984, Volume: 35, Issue:6

    Topics: Aldosterone; Amiloride; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrochlorothi

1984
Effect of angiotensin III on blood pressure, renin-angiotensin-aldosterone system in normal and hypertensive subjects.
    Japanese heart journal, 1984, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Angiotensin III; Blood Pressure; Female; Humans; Hyd

1984
[Changes in the renin-angiotensin-aldosterone and kallikrein systems in normo- and hypertensive pregnant women].
    Akusherstvo i ginekologiia, 1984, Volume: 23, Issue:2

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Kallikreins; Pregnancy; Pregnancy Complications, C

1984
[Nyctohemeral values of plasma renin and aldosterone in relation to age, sex and sodium intake and posture].
    Cardiologia (Rome, Italy), 1983, Volume: 28, Issue:7

    Topics: Adolescent; Adult; Age Factors; Aged; Aldosterone; Circadian Rhythm; Diet; Female; Humans; Hypertens

1983
A case of normotensive primary aldosteronism--comparison with 13 previously experienced cases with hypertension.
    Endocrinologia japonica, 1984, Volume: 31, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Female; Humans; Hyperaldosteronism; H

1984
[Study on renin-angiotensin-aldosterone system. II. Changes of plasma renin activity, plasma aldosterone concentration and urinary sodium excretion in the hypertensives].
    Nihon Jinzo Gakkai shi, 1984, Volume: 26, Issue:2

    Topics: Adult; Aldosterone; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Aged; Renin;

1984
[Features of vascular reactivity, sodium metabolism and its humoral regulation in healthy subjects with a family history of hypertension].
    Kardiologiia, 1984, Volume: 24, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Middle Aged; Norepin

1984
Primary aldosteronism due to adrenal carcinomas.
    Klinische Wochenschrift, 1984, May-15, Volume: 62, Issue:10

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Combined Modality Therapy; Female; Foll

1984
Acute effect of captopril on serum lipid peroxides level in hypertensive patients.
    The Tohoku journal of experimental medicine, 1984, Volume: 143, Issue:1

    Topics: Adult; Aldosterone; Captopril; Female; Humans; Hypertension; Lipid Peroxides; Male; Proline; Renin-A

1984
[Juvenile essential hypertension. II. Plasma renin activity and levels of aldosterone at rest and after loading in children with juvenile essential hypertension].
    Ceskoslovenska pediatrie, 1984, Volume: 39, Issue:5

    Topics: Adolescent; Aldosterone; Cold Temperature; Humans; Hypertension; Posture; Renin

1984
[Dopaminergic modulation of salt sensitivity in essential hypertension].
    Nihon Jinzo Gakkai shi, 1984, Volume: 26, Issue:4

    Topics: Aldosterone; Catecholamines; Diet, Sodium-Restricted; Dopamine; Female; Humans; Hypertension; Male;

1984
[Comparison of effects of two angiotensin II antagonists on blood pressure, heart rate, plasma renin activity, and plasma aldosterone concentration in the same hypertensive patients].
    Nihon Jinzo Gakkai shi, 1984, Volume: 26, Issue:4

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Angiotensin II; Blood Pressure; Heart R

1984
[Effects of guanabenz on plasma renin and aldosterone and on sodium balance in hypertensive patients].
    Minerva cardioangiologica, 1984, Volume: 32, Issue:5

    Topics: Adult; Aldosterone; Female; Guanabenz; Guanidines; Humans; Hypertension; Male; Middle Aged; Renin; S

1984
[Effect of guanabenz alone and in association with a diuretic on blood pressure and on the renin-angiotensin-aldosterone system in hypertensive patients].
    Minerva cardioangiologica, 1984, Volume: 32, Issue:5

    Topics: Adult; Aged; Aldosterone; Chlorthalidone; Drug Therapy, Combination; Guanabenz; Guanidines; Heart Ra

1984
[Circadian rhythms of the renin-angiotensin-aldosterone system in hypertension patients].
    Vrachebnoe delo, 1984, Issue:7

    Topics: Aldosterone; Circadian Rhythm; Furosemide; Humans; Hypertension; Renin; Renin-Angiotensin System; Ti

1984
Acute effect of atenolol on hemodynamic, plasma renin activity and plasma aldosterone concentration in the once daily oral administration.
    Japanese circulation journal, 1984, Volume: 48, Issue:9

    Topics: Administration, Oral; Adult; Aldosterone; Atenolol; Blood Pressure; Cardiac Output; Female; Heart Ra

1984
Effect of indapamide on the renin-aldosterone system, and urinary excretion of potassium and calcium in essential hypertension.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:2

    Topics: Adult; Aldosterone; Calcium; Creatinine; Diuretics; Female; Humans; Hypertension; Indapamide; Male;

1984
Clinical syndromes associated with disorders of renal tubular chloride transport: excess and deficiency of a circulating factor?
    Medical hypotheses, 1984, Volume: 14, Issue:4

    Topics: Aldosterone; Angiotensin II; Bartter Syndrome; Body Weight; Chlorides; Female; Furosemide; Humans; H

1984
Circulatory volume in essential hypertension. Relationships with age, blood pressure, exchangeable sodium, renin, aldosterone and catecholamines.
    Mineral and electrolyte metabolism, 1984, Volume: 10, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Blood Pressure; Blood Volume; Body Height; Body Surface

1984
Renin, angiotensin II, aldosterone, catecholamines, prostaglandins and vasopressin. The importance of pressor and depressor factors for hypertension in pregnancy.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1984, Volume: 169

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Catecholamines; Female; Humans

1984
Hemodynamic effects of a competitive renin inhibitory peptide in humans: evidence for multiple mechanisms of action.
    Transactions of the Association of American Physicians, 1983, Volume: 96

    Topics: Adult; Aldosterone; Angiotensinogen; Blood Pressure; Captopril; Drug Interactions; Heart Rate; Hemod

1983
Characteristics of hypertension in primary IgA glomerulonephritis.
    Contributions to nephrology, 1984, Volume: 40

    Topics: Adolescent; Adult; Aldosterone; Child; Female; Glomerulonephritis, IGA; Humans; Hypertension; Indome

1984
[Radioimmunoassay in the diagnosis of arterial hypertension].
    Meditsinskaia radiologiia, 1984, Volume: 29, Issue:11

    Topics: Adrenal Gland Neoplasms; Aldosterone; Catecholamines; Diagnosis, Differential; Humans; Hyperaldoster

1984
Abnormal relation of extracellular fluid volume and exchangeable sodium with systemic arterial pressure in early borderline essential hypertension.
    The American journal of cardiology, 1984, Dec-01, Volume: 54, Issue:10

    Topics: Adult; Aldosterone; Blood Pressure; Extracellular Space; Female; Homeostasis; Humans; Hypertension;

1984
Comparison of the effects of diuretic therapy and low sodium intake in isolated systolic hypertension.
    The American journal of medicine, 1984, Volume: 77, Issue:6

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Diuretics; Female; H

1984
Therapeutic effect of exercise on hypertension.
    European journal of applied physiology and occupational physiology, 1984, Volume: 53, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Female; Heart Rate; Humans; Hypertension; Lactat

1984
Comparison of long-term renal hemodynamic effects of methyldopa and propranolol in patients with hypertension and renal insufficiency.
    Journal of clinical pharmacology, 1984, Volume: 24, Issue:10

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Female; Furosemide; Humans; Hypertension; Kidney Diseases;

1984
Effects of single dose administration of angiotension covering enzyme inhibitor (captopril) on blood pressure, plasma renin activity and plasma aldosterone in patients with essential hypertension. A proposal for the captopril test.
    Nihon Jinzo Gakkai shi, 1984, Volume: 26, Issue:9

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Female; Furosemide; Humans; Hypertension; Male; Middl

1984
Effect of a moderately energy- and salt-reduced diet on body compartments and blood pressure control in obese men with mild hypertension.
    Acta medica Scandinavica, 1984, Volume: 216, Issue:4

    Topics: Adipose Tissue; Aldosterone; Blood Pressure; Body Composition; Body Fluid Compartments; Diet, Reduci

1984
Prediction of hyperkalemia associated with prolonged treatment with captopril by glucose-induced acute serum potassium changes.
    Experimental and clinical endocrinology, 1984, Volume: 84, Issue:2

    Topics: Aldosterone; Blood Pressure; Captopril; Glucose; Glucose Tolerance Test; Humans; Hyperkalemia; Hyper

1984
[Is there a relation between the renin-angiotensin-aldosterone system and vasopressin secretion in essential hypertension?].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1984, Dec-01, Volume: 39, Issue:23

    Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Diet, Sodium-Restricted; Female; Humans; H

1984
[Recent findings on mineralocorticoids].
    Nihon Naibunpi Gakkai zasshi, 1984, Dec-20, Volume: 60, Issue:12

    Topics: Aldosterone; Animals; Circadian Rhythm; Humans; Hyperaldosteronism; Hypertension; Kidney; Mineraloco

1984
Intracellular concentration and transmembrane fluxes of sodium and potassium in erythrocytes of white normal male subjects with and without a family history of hypertension.
    Journal of hypertension, 1984, Volume: 2, Issue:1

    Topics: Aldosterone; Erythrocyte Membrane; Erythrocytes; Furosemide; Humans; Hypertension; Kallikreins; Male

1984
Calf muscle haemodynamics and the renin-angiotensin-aldosterone system in normotensive subjects with a familial predisposition to hypertension: changes during increased salt intake.
    Journal of hypertension, 1984, Volume: 2, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Hemodynamics; Humans; Hypertension;

1984
Enhanced response of plasma aldosterone to metoclopramide in essential hypertension.
    Journal of hypertension, 1984, Volume: 2, Issue:2

    Topics: Adult; Aldosterone; Humans; Hypertension; Male; Metoclopramide; Middle Aged; Posture; Potassium; Ren

1984
Does potassium lower blood pressure by increasing sodium excretion? A metabolic study in patients with mild to moderate essential hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1983, Volume: 1, Issue:2

    Topics: Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Potass

1983
The natriuretic response to acute saline loading in normotensive and hypertensive renal transplant recipients.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1983, Volume: 1, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Creatinine; Female; Humans; Hypertension; Kidney Transplantation

1983
Failure of angiotensin II to reduce plasma renin activity in hypertensive pregnant women.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Drug Evaluation; Female; Humans; Hypertension; M

1984
[Effects of potassium on renin and aldosterone].
    Archives des maladies du coeur et des vaisseaux, 1984, Volume: 77 Spec No

    Topics: Aldosterone; Diuretics; Humans; Hypertension; Potassium; Renin

1984
Direct and indirect measurement of urinary kallikrein excretion in patients with essential hypertension and normotensives: relation to age and plasma renin and aldosterone levels.
    European journal of clinical investigation, 1984, Volume: 14, Issue:3

    Topics: Adult; Age Factors; Aldosterone; Female; Humans; Hypertension; Kallikreins; Male; Middle Aged; Potas

1984
'Essential' hypertension with hypokalemia. Caused by aldosterone-secreting adrenal adenoma.
    Postgraduate medicine, 1984, Volume: 76, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Aged; Aldosterone; Chronic Disease; Humans; Hyperaldosteronism; Hy

1984
Metabolic and mechanical properties of aortas from aldosterone-salt hypertensive rats.
    Circulation research, 1984, Volume: 55, Issue:3

    Topics: Aldosterone; Animals; Aorta; Biological Transport; Biomechanical Phenomena; Energy Metabolism; Hyper

1984
Irvine H. Page lecture 1982. A new look at the old mosaic.
    Cleveland Clinic quarterly, 1984,Summer, Volume: 51, Issue:2

    Topics: Aldosterone; Animals; Hemodynamics; Homeostasis; Humans; Hypertension; Hypertension, Renal; Water-El

1984
Oral potassium chloride and amiloride in hydrochlorothiazide-induced potassium loss.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:4

    Topics: Administration, Oral; Adult; Aldosterone; Amiloride; Biological Availability; Creatinine; Drug Evalu

1984
[A simple radioimmunoassay determination of urinary aldosterone using 125I-labeled ligand [ALDOCTK-125KIT] and its clinical application].
    Nihon Naibunpi Gakkai zasshi, 1984, May-20, Volume: 60, Issue:5

    Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Cushing Syndrome; Female; Glomerulonephritis; Huma

1984
Adrenocortical function in the course of long-term verapamil treatment.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1984, Volume: 16, Issue:7

    Topics: Adrenal Cortex; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged;

1984
Primary hyperaldosteronism during pregnancy.
    American journal of obstetrics and gynecology, 1984, Nov-15, Volume: 150, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi

1984
Cardiovascular and adrenal sensitivity to angiotensin II in essential hypertension.
    Klinische Wochenschrift, 1984, Dec-03, Volume: 62, Issue:23

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension;

1984
[Current aspects of diuretic use].
    Zeitschrift fur arztliche Fortbildung, 1984, Volume: 78, Issue:23

    Topics: Aldosterone; Benzothiadiazines; Calcium; Carbonic Anhydrase Inhibitors; Diuretics; Diuretics, Osmoti

1984
Flurbiprofen interaction with single doses of atenolol and propranolol.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:6

    Topics: Adult; Aldosterone; Atenolol; Blood Pressure; Body Weight; Female; Flurbiprofen; Heart Rate; Humans;

1984
The adrenal cortex and hypertension.
    Primary care, 1983, Volume: 10, Issue:1

    Topics: Adrenal Cortex; Aldosterone; Cushing Syndrome; Diagnosis, Differential; Glucocorticoids; Humans; Hyp

1983
[The effect of dopaminergic stimulation and inhibition on the urinary excretion of aldosterone and kallikrein in spontaneously hypertensive rats].
    Bollettino della Societa italiana di biologia sperimentale, 1983, Oct-30, Volume: 59, Issue:10

    Topics: Aldosterone; Animals; Bromocriptine; Dopamine; Hypertension; Kallikreins; Male; Metoclopramide; Natr

1983
[Relation between kallikreinuria and the renin-angiotensin-aldosterone system in patients with arterial hypertension].
    Kardiologia polska, 1984, Volume: 27, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Kallikreins; Male; Middle Aged; Re

1984
[Effects of salt loading on urinary excretion of kallikrein in normotensive subjects and patients with essential hypertension].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1984, Volume: 73, Issue:8

    Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Kallikreins; Male; Middle Aged; Refere

1984
Relation of rates of excretion of urinary prostaglandin E metabolites to administration of angiotensin, aldosterone, and spironolactone in vivo.
    Prostaglandins, leukotrienes, and medicine, 1984, Volume: 14, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Angiotensin II; Animals; Hypertension; Male; Prostagland

1984
Pre-eclampsia: a hypothesis for its pathogenesis.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 118

    Topics: Aldosterone; Female; Glomerular Filtration Rate; Humans; Hypertension; Posture; Pre-Eclampsia; Pregn

1984
[Water and electrolyte distribution and indices of central hemodynamics in patients with hypertension with different levels of urinary excretion of catecholamines and different plasma levels of aldosterone and cortisol].
    Terapevticheskii arkhiv, 1983, Volume: 55, Issue:5

    Topics: Adolescent; Adult; Aged; Aldosterone; Catecholamines; Female; Hemodynamics; Humans; Hydrocortisone;

1983
[Strategy for hormonal study in the arterial hypertension of acromegaly].
    Annales de medecine interne, 1983, Volume: 134, Issue:3

    Topics: Acromegaly; Adenoma; Adrenal Gland Neoplasms; Aldosterone; Body Fluid Compartments; Diet, Sodium-Res

1983
[Possible correlation between intralymphocytic sodium and plasma aldosterone].
    La Clinica terapeutica, 1983, Aug-31, Volume: 106, Issue:4

    Topics: Aldosterone; Humans; Hypertension; Liver Cirrhosis; Lymphocytes; Sodium

1983
Corticosteroid modulation of the renin system and blood pressure in the spontaneously hypertensive rat.
    Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:9

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Aldosterone; Angiotensinogen; Animals; Blood

1983
Predictability of antihypertensive efficacy of selective beta 1 blockers.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:6

    Topics: Adult; Aldosterone; Atenolol; Blood Pressure; Cardiac Output; Catecholamines; Echocardiography; Fema

1983
Potassium load in spontaneously hypertensive rats. Effects on blood pressure, renin-angiotensin, aldosterone, and intracellular electrolytes.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1983, Volume: 183, Issue:2

    Topics: Aldosterone; Animals; Blood Pressure; Calcium; Electrolytes; Hypertension; Intracellular Fluid; Male

1983
Effects of bromocriptine on the circadian rhythm of 18-hydroxycorticosterone and cortisol secretion in essential hypertensives.
    Journal of hypertension, 1983, Volume: 1, Issue:2

    Topics: 18-Hydroxycorticosterone; Adult; Aldosterone; Bromocriptine; Circadian Rhythm; Corticosterone; Human

1983
Relation of blood pressure with body and plasma electrolytes in Conn's syndrome.
    Journal of hypertension, 1983, Volume: 1, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Electrolytes; Female; Humans; Hyperaldosteronism; Hypertension;

1983
The antihypertensive effect of dietary potassium chloride loading in rats with adrenal regeneration hypertension.
    Clinical science (London, England : 1979), 1984, Volume: 66, Issue:2

    Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Blood Proteins; Corticosterone; Electrolytes;

1984
Blood pressure and intra-erythrocyte sodium during normal and high salt intake in middle-aged men: relationship to family history of hypertension, and neurogenic and hormonal variables.
    Clinical science (London, England : 1979), 1984, Volume: 66, Issue:4

    Topics: Aldosterone; Blood Pressure; Body Weight; Diet; Dopamine; Epinephrine; Erythrocytes; Heart Rate; Hum

1984
The renin-angiotensin-aldosterone system and circadian rhythm of urine variables in normotensive and hypertensive subjects.
    Japanese circulation journal, 1984, Volume: 48, Issue:2

    Topics: Aldosterone; Animals; Blood Pressure; Catecholamines; Chlorine; Circadian Rhythm; Creatinine; Humans

1984
Primary aldosteronism. Clinical management.
    Archives of surgery (Chicago, Ill. : 1960), 1984, Volume: 119, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Diagnosis, Di

1984
Relationship between plasma aldosterone and angiotensin II before and after noradrenergic inhibition in normal subjects and patients with mild essential hypertension.
    The Journal of clinical endocrinology and metabolism, 1984, Volume: 59, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Debrisoquin; Female; Humans; Hypertension;

1984
Adrenal adenoma with 18-hydroxycorticosterone excess and hypertension: a variant of aldosteronomas.
    Hormone research, 1984, Volume: 19, Issue:4

    Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Aldosterone; Corticosterone; Female; Hum

1984
Hypertension and age: clinical and biochemical correlates.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:7

    Topics: Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Blood Volume; Furosemide; Humans; Hypertensio

1982
Enhanced renin levels after discontinuation of furosemide: additional effects of loop diuretics on renin release.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:8

    Topics: Adult; Aged; Aldosterone; Furosemide; Humans; Hypertension; Kidney Function Tests; Male; Middle Aged

1982
Alcohol and hypertension.
    Contributions to nephrology, 1982, Volume: 30

    Topics: Adult; Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Aldosterone; Blood Pressure; Dopam

1982
Endocrine factors in juvenile essential hypertension.
    Japanese journal of medicine, 1982, Volume: 21, Issue:2

    Topics: Adult; Aldosterone; Corticosterone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hypertensi

1982
The effect of high-sodium intake and furosemide on blood pressure and other related variables in salt-sensitive hypertension.
    Japanese journal of medicine, 1982, Volume: 21, Issue:2

    Topics: Aldosterone; Blood Pressure; Cardiac Output; Diet; Dinoprostone; Furosemide; Humans; Hypertension; N

1982
Effect of ageing on circadian rhythms of plasma renin and aldosterone in mesor-hypertensive women.
    Maturitas, 1982, Volume: 4, Issue:2

    Topics: Adolescent; Adult; Aging; Aldosterone; Circadian Rhythm; Female; Humans; Hypertension; Menstruation;

1982
Hypertension in adult onset diabetes mellitus: abnormal renal hemodynamics and endogenous vasoregulatory factors.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1982, Volume: 2, Issue:2

    Topics: Aldosterone; Blood Glucose; Blood Pressure; Blood Volume; Diabetes Complications; Diabetes Mellitus;

1982
Hemodynamic and endocrine changes associated with captopril in diuretic-resistant hypertensive patients.
    The American journal of medicine, 1982, Volume: 73, Issue:3

    Topics: Adult; Aldosterone; Benzothiadiazines; Blood Pressure; Captopril; Cardiac Output; Diuretics; Female;

1982
Identifying aldosterone-producing adenoma.
    Archives of internal medicine, 1982, Volume: 142, Issue:10

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension; Renin

1982
Circadian blood pressure and renin, aldosterone, cortisol, and prolactin levels in hypertensive pseudohypoparathyroid patients.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 55, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Circadian Rhythm; Female; Hormones; Humans; Hydrocortisone; Hype

1982
Rapid increase of mineralocorticoids after furosemide in low-renin essential hypertension: evidence for 18-hydroxycorticosterone to be a better marker than aldosterone.
    Klinische Wochenschrift, 1982, Aug-16, Volume: 60, Issue:16

    Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adult; Aldosterone; Corticosterone; Female

1982
The renin-aldosterone system in pre-eclampsia, essential and transient hypertension during pregnancy, and normotensive pregnant and non-pregnant control subjects.
    Acta endocrinologica, 1982, Volume: 101, Issue:2

    Topics: Aldosterone; Blood Pressure; Creatinine; Female; Humans; Hypertension; Potassium; Pre-Eclampsia; Pre

1982
Long-term captopril treatment in moderate to severe hypertension.
    British journal of clinical pharmacology, 1982, Volume: 14 Suppl 2

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Captopril; Diuretics; Drug Therapy, Combination; Female; H

1982
Prostaglandins, catecholamines, renin and aldosterone during hypertensive and normotensive pregnancy.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: Aldosterone; Dinoprost; Dinoprostone; Epinephrine; Female; Humans; Hypertension; Norepinephrine; Pre

1982
Aldosterone and its metabolism in spontaneously hypertensive rats (SHR).
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Hypertension; Kinetics; Male; Potassium; Rats;

1982
Simplified screening procedures for primary aldosteronism. Studies on the mechanism of the hyper-responsiveness to furosemide and standing.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: Aldosterone; Blood Pressure; Furosemide; Humans; Hyperaldosteronism; Hypertension; Mass Screening; P

1982
Recurrence of hypertension in primary aldosteronism after discontinuation of spironolactone. Time course of changes in cardiac output and body fluid volumes.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: Aldosterone; Blood Pressure; Cardiac Output; Humans; Hyperaldosteronism; Hypertension; Potassium; Re

1982
Renin subgroups in essential hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: Aldosterone; Blood Pressure; Creatinine; Female; Heart Rate; Hematocrit; Humans; Hypertension; Kidne

1982
Characterization of a group of essential hypertensives with impaired regulation of aldosterone.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension;

1982
The salivary sodium/potassium ratio in hypertension: relation to race and plasma renin activity.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: Adult; Aldosterone; Black People; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Middle A

1982
The role of aldosterone in the response to treatment of primary hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Chlorthalidone; Female; Humans; Hypertension; Male; Middle

1982
Glucose-induced hyperkalemia developing in the upright position in captopril-treated hypertensives.
    Research communications in chemical pathology and pharmacology, 1982, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Aged; Aldosterone; Captopril; Diabetes Mellitus; Female; Glucose; Glucose Toleran

1982
Sodium and potassium status, plasma renin and aldosterone profiles in normotensive and hypertensive Johannesburg blacks.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1982, Dec-11, Volume: 62, Issue:25

    Topics: Adult; Aldosterone; Black or African American; Blood Pressure; Creatinine; Female; Humans; Hypertens

1982
Plasma volume, electrolyte, and endocrine changes during onset of laminitis hypertension in horses.
    American journal of veterinary research, 1982, Volume: 43, Issue:9

    Topics: Acute Disease; Aldosterone; Animals; Electrolytes; Female; Horse Diseases; Horses; Hydrocortisone; H

1982
Renal function in borderline hypertensive first-degree relatives of essential hypertensives. Effects of sodium load.
    Cardiology, 1982, Volume: 69, Issue:5

    Topics: Adolescent; Adult; Aldosterone; Electrolytes; Female; Humans; Hypertension; Kidney; Kidney Function

1982
Humoral mechanisms of arterial hypertension in patients in the acute phase of myocardial infarction.
    Cor et vasa, 1982, Volume: 24, Issue:5

    Topics: Adult; Aged; Aldosterone; Catecholamines; Female; Hemodynamics; Humans; Hydrocortisone; Hypertension

1982
Increased adrenergic activity during pregnancy-induced hypertension.
    European heart journal, 1982, Volume: 3 Suppl C

    Topics: Adult; Aldosterone; Epinephrine; Female; Humans; Hypertension; Norepinephrine; Pregnancy; Pregnancy

1982
The renin-angiotensin-aldosterone system and blood pressure during oxprenolol treatment in hypertensive patients pretreated with diuretics.
    International journal of clinical pharmacology, therapy, and toxicology, 1982, Volume: 20, Issue:11

    Topics: Adult; Aldosterone; Amiloride; Blood Pressure; Body Weight; Diuretics; Drug Combinations; Female; Hu

1982
[Effect of prazosin on catecholamines, renin-aldosterone system and prostaglandins in primary hypertension].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Jun-21, Volume: 37, Issue:18

    Topics: Adult; Aldosterone; Catecholamines; Female; Humans; Hypertension; Male; Middle Aged; Prazosin; Prost

1982
[Circadian rhythms of renin, aldosterone and cortisol in essential arterial hypertension with recent, confirmed and complicated appearance].
    Bollettino della Societa italiana di cardiologia, 1981, Volume: 26, Issue:10

    Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Female; Humans; Hydrocortisone; Hypertension; Male

1981
[Evaluation and correlation of various hemodynamic and humoral parameters in stable essential hypertension].
    Bollettino della Societa italiana di cardiologia, 1981, Volume: 26, Issue:11

    Topics: Adult; Aldosterone; Blood Volume; Cardiovascular System; Humans; Hypertension; Middle Aged; Renin

1981
Enhanced vascular reactivity to norepinephrine in salt-sensitive patients with hypertension.
    Japanese heart journal, 1982, Volume: 23, Issue:6

    Topics: Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Midd

1982
[Urinary excretion of aldosterone in patients with hypertension].
    Vutreshni bolesti, 1982, Volume: 21, Issue:5

    Topics: Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Plasma Volume; Potassium;

1982
Renin angiotensin aldosterone system and adrenergic system in normotensive and hypertensive pregnancy.
    Clinical and experimental hypertension. Part B, Hypertension in pregnancy, 1982, Volume: 1, Issue:4

    Topics: Adult; Aldosterone; Epinephrine; Female; Humans; Hypertension; Norepinephrine; Pregnancy; Pregnancy

1982
The sympathetic nervous system in primary hypertension.
    Mineral and electrolyte metabolism, 1982, Volume: 7, Issue:2

    Topics: Adult; Age Factors; Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Nore

1982
Effects of various doses of captopril on plasma aldosterone concentrations in patients with essential hypertension.
    Endocrinologia japonica, 1982, Volume: 29, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Female; Humans; Hyp

1982
[Catecholamines in the blood and the renin-angiotensin-aldosterone axis in essential hypertension].
    Bollettino della Societa italiana di cardiologia, 1981, Volume: 26, Issue:12

    Topics: Adult; Aldosterone; Angiotensin II; Catecholamines; Electrolytes; Female; Humans; Hypertension; Male

1981
[Adrenergic factors in the hemodynamic adaptation to effort].
    Archives des maladies du coeur et des vaisseaux, 1981, Volume: 74, Issue:1

    Topics: Adaptation, Physiological; Aldosterone; Catecholamines; Hemodynamics; Humans; Hypertension; Labetalo

1981
Leucocyte cation transport in essential hypertension: its relation to the renin-angiotensin system.
    British medical journal (Clinical research ed.), 1981, Apr-18, Volume: 282, Issue:6272

    Topics: Aldosterone; Angiotensin II; Biological Transport; Diet, Sodium-Restricted; Humans; Hypertension; Le

1981
Relation between arterial pressure, dietary sodium intake, and renin system in essential hypertension.
    British medical journal (Clinical research ed.), 1981, Jul-11, Volume: 283, Issue:6284

    Topics: Adult; Aldosterone; Blood Pressure; Diet; Diet, Sodium-Restricted; Female; Humans; Hypertension; Mal

1981
Investigation of the mechanism of action of prostaglandin synthesis inhibitors on renin and aldosterone secretion and sodium excretion.
    Prostaglandins and medicine, 1981, Volume: 7, Issue:2

    Topics: Adult; Aldosterone; Cyclooxygenase Inhibitors; Humans; Hypertension; Indomethacin; Male; Middle Aged

1981
Catecholamines, renin, aldosterone, and blood volume during chronic minoxidil therapy.
    Klinische Wochenschrift, 1981, Nov-16, Volume: 59, Issue:22

    Topics: Aldosterone; Blood Volume; Epinephrine; Female; Humans; Hypertension; Long-Term Care; Male; Middle A

1981
The effect of captopril on catecholamines, renin activity, angiotensin II and aldosterone in plasma during physical exercise in hypertensive patients.
    European journal of clinical investigation, 1981, Volume: 11, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Catecholamines; Female; Humans; Hyper

1981
Responsiveness of the renin-aldosterone system during exercise in young patients with essential hypertension.
    European journal of clinical investigation, 1981, Volume: 11, Issue:5

    Topics: Adult; Aldosterone; Blood Pressure; Blood Proteins; Female; Heart Rate; Humans; Hypertension; Male;

1981
Reduction of plasma and urinary vasopressin during treatment of severe hypertension by captopril.
    European journal of clinical investigation, 1981, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middl

1981
Long-term efficacy of captopril in renovascular and essential hypertension.
    The American journal of cardiology, 1982, Apr-21, Volume: 49, Issue:6

    Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Female

1982
Captopril in the long-term treatment of essential hypertension: changes in the renin-angiotensin-aldosterone system.
    The American journal of cardiology, 1982, Apr-21, Volume: 49, Issue:6

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Dose-Response Relationship, D

1982
Long-term treatment of childhood hypertension with captopril.
    Pediatric annals, 1982, Volume: 11, Issue:7

    Topics: Adolescent; Adult; Aldosterone; Captopril; Child; Electrocardiography; Female; Humans; Hypertension;

1982
[The renin-angiotensin system and the sympathetic nervous system in essential hypertension].
    Archives des maladies du coeur et des vaisseaux, 1982, Volume: 75 Spec No

    Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Epinephrine; Female; Humans; Hypertension; Male; Mi

1982
[The renin-angiotensin-aldosterone system and the adrenergic system in normal pregnancy and hypertension induced by pregnancy].
    Archives des maladies du coeur et des vaisseaux, 1982, Volume: 75 Spec No

    Topics: Aldosterone; Epinephrine; Female; Humans; Hypertension; Norepinephrine; Pregnancy; Pregnancy Complic

1982
Effects on the renin-angiotensin system of agents acting at central and peripheral adrenergic receptors.
    Chest, 1983, Volume: 83, Issue:2 Suppl

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Clonidine; Double-Blind Method; Female; Humans; Hypertensi

1983
Achievements in hypertension: a 25 year overview.
    Journal of the American College of Cardiology, 1983, Volume: 1, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Obesity; Renin-Angiotensin

1983
Aldosterone 21-sulphate in man.
    Journal of steroid biochemistry, 1983, Volume: 18, Issue:4

    Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Animals; Biological A

1983
Hypersensitivity of spontaneously hypertensive rats to heat and ether before the onset of high blood pressure.
    Endocrinology, 1983, Volume: 112, Issue:1

    Topics: Adrenal Glands; Aldosterone; Animals; Ascorbic Acid; Blood Pressure; Cholesterol; Corticosterone; Et

1983
[Changes in water-sodium balance in patients with hypertension subjected to different types of hypotensive therapy].
    Kardiologiia, 1983, Volume: 23, Issue:4

    Topics: Adult; Aged; Aldosterone; Angiotensin I; Chlorthalidone; Extracellular Space; Female; Hemodynamics;

1983
[Total plasma aldosterone content in hypertension].
    Kardiologiia, 1983, Volume: 23, Issue:4

    Topics: Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Plasma Volume

1983
Renal denervation and sodium balance in young spontaneously hypertensive rats.
    Renal physiology, 1983, Volume: 6, Issue:3

    Topics: Aldosterone; Animals; Denervation; Hypertension; Kidney; Male; Rats; Rats, Mutant Strains; Sodium

1983
Aldosterone metabolites and possible aldosterone precursors in hypertension.
    Journal of steroid biochemistry, 1983, Volume: 19, Issue:1A

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Antigen-Antibody Comple

1983
[Current neurohumoral and therapeutic aspects of hypertension].
    Vestnik Akademii meditsinskikh nauk SSSR, 1981, Issue:9

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Female; Humans; Hypertension; Kallikreins; Male;

1981
Primary hyperaldosteronism in pregnancy.
    Australian and New Zealand journal of medicine, 1982, Volume: 12, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Female; Humans; Hyperaldosteron

1982
Tobacco chewer's hypokalemia: licorice revisited.
    The New England journal of medicine, 1980, Apr-03, Volume: 302, Issue:14

    Topics: Aged; Aldosterone; Alkalosis; Glycyrrhiza; Humans; Hypertension; Hypokalemia; Male; Nicotiana; Plant

1980
Fludrocortisone suppression test in normal subjects, in patients with essential hypertension and in patients with various forms of aldosteronism.
    Acta endocrinologica, 1980, Volume: 93, Issue:1

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosteron

1980
Acute effects of saralasin on plasma aldosterone in different pathophysiological conditions.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Bartter Syndrome; Child; Diet, Sodium-Restricted; Fe

1980
[Hemodynamics and the renin-angiotensin-aldosterone system in primary hypertension].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Feb-11, Volume: 35, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Hemodynamics; Humans; Hypertension; Male; Middle Age

1980
Hypertension in a four-year-old child: gas chromatographic and mass spectrometric evidence for deficient hepatic metabolism of steroids.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:4

    Topics: Aldosterone; Alkalosis; Child, Preschool; Gas Chromatography-Mass Spectrometry; Humans; Hypertension

1980
[Plasma renin, aldosterone, and dopamine-beta-hydroxylase activity in hypertensive patients over 70 years of age (author's transl)].
    La Nouvelle presse medicale, 1980, Mar-22, Volume: 9, Issue:14

    Topics: Aged; Aldosterone; Dopamine beta-Hydroxylase; Female; Humans; Hypertension; Male; Posture; Renin

1980
Prostaglandins and plasma renin activity in hypertensive patients.
    Advances in prostaglandin and thromboxane research, 1980, Volume: 7

    Topics: Adult; Aldosterone; Blood Pressure; Electrolytes; Glomerular Filtration Rate; Humans; Hypertension;

1980
The effect of clonidine on renin and aldosterone of hypertensive patients.
    International journal of clinical pharmacology, therapy, and toxicology, 1980, Volume: 18, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Hydrocortisone; Hypertens

1980
Integrated concentration of epinephrine and norepinephrine in normal subjects and in patients with mild essential hypertension.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:5

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Child; Epinephrine; Humans; Hydrocortisone; Hyperten

1980
Saralasin infusion in renovascular and essential hypertension.
    The Netherlands journal of medicine, 1980, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Heart Rate; Humans; Hyperten

1980
[Pathogenesis of arterial hypertension].
    Vrachebnoe delo, 1980, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; M

1980
Radioreceptor assay of plasma mineralocorticoid activity. Role of aldosterone, cortisol, and deoxycorticosterone in various mineralocorticoid-excess states.
    Circulation research, 1980, Volume: 46, Issue:6 Pt 2

    Topics: Adolescent; Aldosterone; Binding, Competitive; Child, Preschool; Desoxycorticosterone; Humans; Hydro

1980
Body fluid volumes and the response of renin and aldosterone to short- and long-term thiazide therapy of essential hypertension.
    Acta medica Scandinavica, 1980, Volume: 207, Issue:4

    Topics: Adult; Aldosterone; Extracellular Space; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male

1980
Neurogenic factors in low renin essential hypertension.
    The American journal of medicine, 1980, Volume: 69, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aldosterone; Blood Pressure; Epinephrine; Female; Furosemide; Humans

1980
Evidence for a subgroup of essential hypertensives with non-suppressible excretion of aldosterone during sodium loading.
    Klinische Wochenschrift, 1980, May-02, Volume: 58, Issue:9

    Topics: Aldosterone; Humans; Hypertension; Potassium; Renin; Sodium; Spironolactone

1980
Renin-hyporesponsiveness in essential hypertension. Dissociation between plasma renin and catecholamines or aldosterone following furosemide.
    Klinische Wochenschrift, 1980, May-02, Volume: 58, Issue:9

    Topics: Adult; Aged; Aldosterone; Catecholamines; Female; Furosemide; Humans; Hypertension; Male; Middle Age

1980
Hypertension in the elderly.
    Modern concepts of cardiovascular disease, 1980, Volume: 49, Issue:8

    Topics: Adult; Aged; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Vessels; Blood Volum

1980
Etiological considerations in Gordon's syndrome: possible role of prostaglandins.
    Prostaglandins and medicine, 1980, Volume: 4, Issue:2

    Topics: Acidosis; Aldosterone; Bradykinin; Humans; Hyperkalemia; Hypertension; Kidney; Prostaglandins; Prost

1980
Renin-angiotensin-aldosterone system in arterial hypertension.
    Cor et vasa, 1980, Volume: 22, Issue:1-2

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Fa

1980
The state of certain humoral systems and haemodynamics in healthy subjects and in patients with essential hypertension with excessive salt intake.
    Cor et vasa, 1980, Volume: 22, Issue:1-2

    Topics: Aldosterone; Blood Volume; Diuresis; Furosemide; Hemodynamics; Humans; Hydrocortisone; Hypertension;

1980
Abnormal adrenal and vascular responses to angiotensin II and an angiotensin antagonist in acromegaly.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:2

    Topics: Acromegaly; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restric

1980
The renin-aldosterone system in secondary hypertension: relationship to blood pressure and plasma electrolytes.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1980, Volume: 79, Issue:4

    Topics: Aldosterone; Blood Pressure; Electrolytes; Humans; Hyperaldosteronism; Hypertension; Kidney Failure,

1980
A comparative study on (des-aspartyl1)-angiotensin II and angiotensin II in patients with essential hypertension.
    Japanese heart journal, 1980, Volume: 21, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin III; Blood Pressure; Humans; Hypertension; Middle Ag

1980
Effect of propranolol on the urinary excretion of prostaglandin E and plasma renin activity in hypertensive patients.
    Prostaglandins and medicine, 1980, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male;

1980
Long-term effects of captopril in hypertension.
    Clinical pharmacology and therapeutics, 1980, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Captopril; Child; Electrolytes; Humans; Hypertension

1980
The renin-aldosterone system in low-dose chlorothiazide treatment of hypertensive subjects.
    International journal of clinical pharmacology, therapy, and toxicology, 1980, Volume: 18, Issue:8

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Chlorothiazide; Humans; Hypertension; Middle Aged; R

1980
[Blood volume, plasma renin activity and plasma aldosterone concentration in patients with essential hypertension who were treated for more than ten years (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1980, Jun-06, Volume: 69, Issue:6

    Topics: Adult; Aged; Aldosterone; Blood Volume; Diuretics; Female; Humans; Hypertension; Male; Middle Aged;

1980
A simplified screening test for differentiating primary aldosteronism from essential hypertension with low plasma renin activity.
    Japanese circulation journal, 1980, Volume: 44, Issue:9

    Topics: Aldosterone; Dexamethasone; Diagnosis, Differential; Furosemide; Humans; Hyperaldosteronism; Hyperte

1980
Dopaminergic Modulation of renin activity and aldosterone and prolactin secretion in the spontaneously hypertensive rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1980, Volume: 164, Issue:4

    Topics: Aldosterone; Animals; Blood Pressure; Dopamine Antagonists; Hypertension; Levodopa; Male; Metoclopra

1980
[Renin-angiotensin-aldosterone system in diabetes, arterial hypertension and orthostatic hypotension].
    Vutreshni bolesti, 1980, Volume: 19, Issue:4

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Diabetes Mellitus; Female; Humans; Hyperte

1980
Factors influencing blood pressure in salt-sensitive patients with hypertension.
    The American journal of medicine, 1980, Volume: 69, Issue:3

    Topics: Aldosterone; Autonomic Nervous System; Cardiac Output; Diet, Sodium-Restricted; Female; Furosemide;

1980
Different patterns in essential hypertension and possible choice of antihypertensive drugs.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: Suppl

    Topics: Adult; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Cardiac Output; Catecholamines;

1980
[Renin-angiotensin system. Physiological importance. Methods and study in humans (author's transl)].
    Anesthesie, analgesie, reanimation, 1980, Volume: 37, Issue:7-8

    Topics: Adolescent; Adrenal Gland Diseases; Adult; Aldosterone; Angiotensins; Blood Pressure; Child; Child,

1980
Captopril in clinical hypertension. Changes in components of renin-angiotensin system and in body composition in relation to fall in blood pressure with a note on measurement of angiotensin II during converting enzyme inhibition.
    British heart journal, 1980, Volume: 44, Issue:3

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Captopril; Diuretics; Humans; Hypertension; Potassium;

1980
Relationships between sodium clearance, plasma renin activity, plasma aldosterone, renal hemodynamics and blood pressure in essential hypertension.
    Clinical and experimental hypertension, 1980, Volume: 2, Issue:3-4

    Topics: Aldosterone; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Malignant; Kidney; p-Am

1980
The kallikrein-kinin system in essential hypertension.
    Clinical and experimental hypertension, 1980, Volume: 2, Issue:3-4

    Topics: Adult; Aldosterone; Animals; Bartter Syndrome; Blood Pressure; Bradykinin; Guinea Pigs; Humans; Hype

1980
Urinary kallikrein in normotensive subjects and in patients with essential hypertension.
    Clinical and experimental hypertension, 1980, Volume: 2, Issue:3-4

    Topics: Adult; Aldosterone; Animals; Creatinine; Dogs; Female; Furosemide; Humans; Hypertension; Kallikreins

1980
Dissociated renin-aldosterone response to acute sodium depletion in patients with a previous history of pregnancy-associated hypertension.
    Clinical and experimental hypertension, 1980, Volume: 2, Issue:5

    Topics: Adolescent; Adult; Aldosterone; Bendroflumethiazide; Blood Pressure; Body Weight; Female; Humans; Hy

1980
[Evaluation of the differences in responsiveness of plasma renin activity to five different stimulations in essential hypertension (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1980, Sep-10, Volume: 69, Issue:9

    Topics: Adult; Aged; Aldosterone; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypertension; Male; M

1980
Captopril in diuretic-treated hypertensive patients.
    JAMA, 1980, Dec-05, Volume: 244, Issue:22

    Topics: Aged; Aldosterone; Captopril; Diuretics; Dizziness; Dose-Response Relationship, Drug; Drug Therapy,

1980
Hyperkalemia resulting from captopril administration.
    JAMA, 1980, Dec-05, Volume: 244, Issue:22

    Topics: Aldosterone; Captopril; Humans; Hyperkalemia; Hypertension; Hyponatremia; Male; Middle Aged; Mineral

1980
Renal function, plasma renin, and spontaneous diuresis in an advanced stage of hypertension in rats.
    Japanese heart journal, 1980, Volume: 21, Issue:5

    Topics: Aldosterone; Animals; Blood Pressure; Diuresis; Electrolytes; Hypertension; Kidney; Male; Rats; Reni

1980
Plasma catecholamines, renin and aldosterone during combined alpha- and beta- adrenoceptor blockade in patients with severe arterial hypertension.
    Postgraduate medical journal, 1980, Volume: 56 Suppl 2

    Topics: Adult; Aged; Aldosterone; Body Weight; Epinephrine; Ethanolamines; Female; Humans; Hypertension; Lab

1980
The effect of dietary sodium in infancy on blood pressure and related factors. Studies of infants fed salted and unsalted diets for five months at eight months and eight years of age.
    Acta paediatrica Scandinavica. Supplement, 1980, Volume: 279

    Topics: Aldosterone; Blood Pressure; Child; Diet, Sodium-Restricted; Extracellular Space; Growth; Humans; Hy

1980
[Saralasin in subjects with low renin arterial hypertension].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Jul-15, Volume: 56, Issue:13

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Furosemide; Humans; Hypertension; Male;

1980
Role of haemodynamics, catecholamines and renin in acute hypercalcaemic hypertension in man.
    Clinical science (London, England : 1979), 1980, Volume: 59 Suppl 6

    Topics: Adult; Aged; Aldosterone; Blood Volume; Calcium; Epinephrine; Hematocrit; Hemodynamics; Humans; Hype

1980
Angiotensin II and not sodium status is the major determinant of the agonistic/antagonistic balance of saralasin's actions.
    Clinical science (London, England : 1979), 1980, Volume: 59 Suppl 6

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; M

1980
Changes in endocrine activities relative to obesity in patients with essential hypertension.
    Journal of the American Geriatrics Society, 1981, Volume: 29, Issue:1

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Energy Intake; Female; Humans; Hy

1981
[Essential hypertension with low levels of plasma renin activity: effects of propranolol on aldosteronemia, plasma volume and electrolyte balance].
    La Clinica terapeutica, 1980, Aug-31, Volume: 94, Issue:4

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Plasma Volume; Propranolol; Ren

1980
Suppression of captopril-induced increase in plasma renin activity by des-Asp1-,Ileu8-angiotensin II in man.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 52, Issue:2

    Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Blood Pressure; Captopril; Femal

1981
Role of sympathetic nerve inhibition and body sodium-volume state in the antihypertensive action of clonidine in essential hypertension.
    Kidney international, 1980, Volume: 18, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Clonidine; Epinephrine; Female; Heart Rate; Humans; Hypertension

1980
[Diagnostic significance of the determination of parameters of the renin-angiotensin-aldosterone system].
    Zeitschrift fur medizinische Laboratoriumsdiagnostik, 1980, Volume: 21, Issue:6

    Topics: Adrenal Gland Diseases; Aldosterone; Angiotensins; Humans; Hypertension; Hypokalemia; Kidney Disease

1980
Alteration of the volume-renin component in borderline essential hypertension.
    Clinical and experimental hypertension, 1981, Volume: 3, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Blood Volume; Diet, Sodium-Restricted; Female; Human

1981
[Urinary prostaglandin E in patients with hypertension--relationship to renin-angiotensin-aldosterone system (author's transl)].
    Nihon Jinzo Gakkai shi, 1980, Volume: 22, Issue:6

    Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hyperaldosteronism; Hypertension; Male; Prostagl

1980
Low-renin hypertension with hyperaldosteronism in childhood.
    Progress in biochemical pharmacology, 1980, Volume: 17

    Topics: Aldosterone; Child; Dexamethasone; Glucocorticoids; Humans; Hyperaldosteronism; Hypertension; Remiss

1980
[Renin-angiotensin-aldosterone system in essential hypertension. Inappropriately high plasma aldosterone in young patients with severe hypertension and in older hypertensives].
    Schweizerische medizinische Wochenschrift, 1980, Dec-13, Volume: 110, Issue:50

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aldosterone; Angiotensin II; Female; Humans; Hyperten

1980
Changes in urinary electrolytes versus serum electrolytes during treatment of primary hypertension with chlorthalidone alone and in combination with spironolactone.
    Acta medica Scandinavica, 1981, Volume: 209, Issue:1-2

    Topics: Adult; Aldosterone; Chlorthalidone; Drug Therapy, Combination; Electrolytes; Humans; Hypertension; M

1981
Interaction of minoxidil and captopril in the treatment of refractory hypertension.
    American journal of diseases of children (1960), 1981, Volume: 135, Issue:3

    Topics: Acidosis; Adolescent; Aldosterone; Captopril; Creatinine; Drug Interactions; Female; Humans; Hyperka

1981
[Pseudo-Conn's syndrome after habitual ingestion of liquorice. Report on various clinical cases].
    Minerva medica, 1981, Apr-02, Volume: 72, Issue:13

    Topics: Adult; Aldosterone; Female; Glycyrrhiza; Humans; Hyperaldosteronism; Hypertension; Middle Aged; Plan

1981
[Physiopathological aspects of arterial hypertension in obese subjects].
    La Radiologia medica, 1980, Volume: 66, Issue:11

    Topics: Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Obesity; Plasma Volume; R

1980
[The dopaminergic system and aldosterone secretion. I. Suppressive effects of L-dopa on secondary hyperaldosteronism].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Nov-30, Volume: 56, Issue:22

    Topics: Adult; Aldosterone; Female; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Levodopa; Male

1980
[The dopaminergic system and aldosterone secretion. II. Effect of L-dopa and dexamethasone on aldosterone biosynthesis].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Nov-30, Volume: 56, Issue:22

    Topics: Adult; Aldosterone; Dexamethasone; Female; Humans; Hydrocortisone; Hypertension; Levodopa; Male; Mid

1980
Effects of captopril on blood pressure, electrolytes, and certain hormones in hypertension.
    Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:6

    Topics: Aldosterone; Blood Pressure; Captopril; Electrolytes; Humans; Hypertension; Posture; Proline; Renin;

1981
[Use of a radioimmunological study sequence for elucidating the role of vasopressor factors in the pathogenesis of hypertension].
    Kardiologiia, 1981, Volume: 21, Issue:3

    Topics: Adult; Aldosterone; Chronic Disease; Coronary Disease; Humans; Hydrocortisone; Hypertension; Male; M

1981
Prolonged clonidine treatment: catecholamines, renin activity and aldosterone following exercise in hypertensives.
    Acta medica Scandinavica, 1981, Volume: 209, Issue:4

    Topics: Adult; Aldosterone; Clonidine; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male; Middle A

1981
[Clinical observation of 12 cases of primary aldosteronism, special reference to the diagnostic problem (author's transl)].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1980, Volume: 55, Issue:5

    Topics: Adrenal Cortex; Adult; Age Factors; Aged; Aldosterone; Circadian Rhythm; Female; Humans; Hyperaldost

1980
Conn's syndrome in a patient with acromegaly.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1981, Volume: 13, Issue:3

    Topics: Acromegaly; Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin II; Female; Humans; Hyperten

1981
Plasma aldosterone response to angiotensin II in sodium-restricted elderly subjects with essential hypertension.
    Journal of the American Geriatrics Society, 1981, Volume: 29, Issue:7

    Topics: Aged; Aging; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; H

1981
[Effects of angiotensin I converting enzyme inhibitor (captopril) on blood pressure, pulse rate, plasma renin activity, and plasma aldosterone concentration in patients with essential hypertension and normal subjects].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1980, Volume: 69, Issue:11

    Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Captopril; Female; Humans; Hypertension; Male;

1980
Alternate day steroids and blood pressure control after renal transplantation.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1980, Volume: 17

    Topics: Aldosterone; Blood Pressure; Drug Administration Schedule; Humans; Hypertension; Immunosuppression T

1980
Prevalence of primary aldosteronism.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 646

    Topics: Adult; Aged; Aldosterone; Denmark; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Ag

1981
Captopril in primary hypertension. Effects related to the renin-angiotensin-aldosterone and kallikrein-kinin systems.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 646

    Topics: Adult; Aldosterone; Angiotensin II; Captopril; Female; Humans; Hypertension; Kallikreins; Kinins; Ma

1981
A pathophysiologic study of the hypertension associated with burn injury in children.
    Annals of surgery, 1981, Volume: 193, Issue:6

    Topics: Acute Disease; Aldosterone; Burns; Catecholamines; Child; Electrolytes; Fluid Therapy; Hemodynamics;

1981
Angiotensin II and sodium as determinants of the agonistic--antagonistic balance of saralasin's actions.
    Clinical science (London, England : 1979), 1981, Volume: 60, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Diet, Sodium-Restricted; Female; Huma

1981
[Effects on long-term treatment with indapamide in subjects with essential arterial hypertension].
    La Clinica terapeutica, 1981, May-31, Volume: 97, Issue:4

    Topics: Adult; Aged; Aldosterone; Diuretics; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; Re

1981
Effects of angiotensin II analog on blood pressure, renin and aldosterone in women on oral contraceptives and toxemia.
    Gynecologic and obstetric investigation, 1981, Volume: 12, Issue:1

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Angiotensin II; Blood Pressure; Contrac

1981
[Renin activity and plasma aldosterone content in hypertension].
    Vrachebnoe delo, 1981, Issue:5

    Topics: Adult; Aldosterone; Enzyme Activation; Humans; Hypertension; Middle Aged; Posture; Renin

1981
Erythrocyte and total body potassium in untreated primary hypertension.
    Acta medica Scandinavica, 1981, Volume: 209, Issue:6

    Topics: Adult; Aldosterone; Body Water; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Potas

1981
Home blood pressure and circadian variation of blood pressure in the evaluation of hypertensive patients.
    Japanese circulation journal, 1981, Volume: 45, Issue:7

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Blood Pressure; Blood Pressure Determination; Cap

1981
Salt intake and hypertension.
    Japanese circulation journal, 1981, Volume: 45, Issue:7

    Topics: Adolescent; Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Diet, Sodium-Restrict

1981
Renal kallikrein-kinin: its relation to renal prostaglandins and renin-angiotensin-aldosterone in man.
    Kidney international, 1981, Volume: 19, Issue:6

    Topics: Adult; Aldosterone; Circadian Rhythm; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypertens

1981
Hypertension following renal transplantation: the role of the host's kidney.
    The Quarterly journal of medicine, 1980,Autumn, Volume: 49, Issue:196

    Topics: Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Kidney; Kidney Transplantation; Middle Age

1980
[Changes in the renin-angiotensin-aldosterone system during graduated ergometric tests in patients with essential arterial hypertension and in normal controls].
    Revista clinica espanola, 1981, May-15, Volume: 161, Issue:3

    Topics: Adrenergic Fibers; Adult; Aldosterone; Angiotensin II; Exercise Test; Female; Humans; Hypertension;

1981
Relationships between blood pressure and plasma renin, aldosterone and dopamine-beta--hydroxylase in the elderly. Studies in patients over 70 years of age.
    Gerontology, 1981, Volume: 27, Issue:5

    Topics: Aged; Aldosterone; Blood Pressure; Dopamine beta-Hydroxylase; Female; Humans; Hypertension; Male; Re

1981
[Effect of salt on the functional state of the renin-angiotensin-aldosterone system in healthy persons and hypertensives].
    Kardiologiia, 1981, Volume: 21, Issue:7

    Topics: Adolescent; Adult; Aldosterone; Diuresis; Humans; Hydrocortisone; Hypertension; Middle Aged; Natriur

1981
[Captopril in the treatment of hypertension (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1981, Aug-25, Volume: 70, Issue:35

    Topics: Aldosterone; Angiotensin II; Captopril; Humans; Hypertension; Proline; Renin

1981
Is renin a risk factor?
    Transactions of the American Clinical and Climatological Association, 1981, Volume: 92

    Topics: Aldosterone; Animals; Aortic Diseases; Arteriosclerosis; Cholesterol, Dietary; Diet, Atherogenic; Hy

1981
Mineralocorticoid and metabolic response to metyrapone on normotensive children and children with dexamethasone-suppressible and primary hyperaldosteronism.
    Acta endocrinologica, 1981, Volume: 98, Issue:1

    Topics: Aldosterone; Child; Desoxycorticosterone; Electrolytes; Female; Humans; Hyperaldosteronism; Hyperten

1981
Captopril withdrawal after chronic therapy.
    Clinical and experimental hypertension, 1981, Volume: 3, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Epinephrine; Female; Humans; Hyperten

1981
Acute effects of a new vasodilator, Ro 12-4713, on blood pressure, plasma Renin activity, Aldosterone and Catecholamine levels, and renal function in hypertensive and normal subjects.
    European journal of clinical pharmacology, 1981, Volume: 20, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Dose-Response Relationship, Drug; Female; Humans

1981
Effect of chronic diuretic treatment on the plasma renin-angiotensin-aldosterone system in essential hypertension.
    British journal of clinical pharmacology, 1981, Volume: 12, Issue:3

    Topics: Adult; Aldosterone; Angiotensins; Diuretics; Electrolytes; Female; Humans; Hydrochlorothiazide; Hype

1981
Primary aldosteronism -- screening, diagnosis and therapy.
    Cor et vasa, 1981, Volume: 23, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Female; Humans; Hyperaldosteron

1981
Relationship between blood pressure and blood levels of angiotensin I converting enzyme inhibitor (SQ 14,225).
    Japanese circulation journal, 1981, Volume: 45, Issue:9

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Chlorides; Endopeptidases; Female; Humans; Hypertensi

1981
Correction of hypertension by partial nephrectomy in segmental renal artery stenosis and electron microscopic studies of renin.
    Japanese heart journal, 1981, Volume: 22, Issue:4

    Topics: Adolescent; Aldosterone; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Kidn

1981
Acute hypercalcemic hypertension in man: role of hemodynamics, catecholamines, and renin.
    Kidney international, 1981, Volume: 20, Issue:1

    Topics: Adult; Aged; Aldosterone; Blood Volume; Dopamine; Epinephrine; Hemodynamics; Humans; Hypercalcemia;

1981
Elevated 'free' 18-hydroxy-corticosterone excretion as a possible indicator for early diagnosis of primary aldosteronism.
    Journal of steroid biochemistry, 1981, Volume: 14, Issue:9

    Topics: 18-Hydroxycorticosterone; Adult; Aldosterone; Corticosterone; Female; Humans; Hyperaldosteronism; Hy

1981
A screening test to identify aldosterone-producing adenoma by measuring plasma renin activity. Results in hypertensive patients.
    Archives of internal medicine, 1981, Volume: 141, Issue:12

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Midd

1981
Screening for surgically correctable hypertension caused by primary aldosteronism.
    Archives of internal medicine, 1981, Volume: 141, Issue:12

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

1981
[The relationship between lymphocyte sodium content and the renin-angiotensin-aldosterone system in subjects with essential arterial hypertension].
    La Clinica terapeutica, 1981, Nov-15, Volume: 99, Issue:3

    Topics: Adult; Aldosterone; Humans; Hypertension; Lymphocytes; Middle Aged; Renin; Renin-Angiotensin System;

1981
Blood pressure and the renin--angiotensin--aldosterone system.
    Clinical science (London, England : 1979), 1981, Volume: 61 Suppl 7

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Middle Aged; Renin; Renin-A

1981
Effect of angiotensin II and converting enzyme inhibitor (captopril) on blood pressure, plasma renin activity and aldosterone in primary aldosteronism.
    Clinical science (London, England : 1979), 1981, Volume: 61 Suppl 7

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Captopril; Humans; Hyperaldosteronism; Hypertension; Pr

1981
Comparison of the effects of captopril, diuretic and their combination in low- and normal-renin essential hypertension.
    Life sciences, 1982, Jan-04, Volume: 30, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Drug Evaluation; Drug Therapy, Combination; Humans; H

1982
The effect of biofeedback-assisted relaxation training on blood pressure and selected biochemical parameters in patients with essential hypertension.
    Biofeedback and self-regulation, 1981, Volume: 6, Issue:3

    Topics: Adrenal Cortex; Adult; Aldosterone; Biofeedback, Psychology; Blood Pressure; Female; Humans; Hydroco

1981
Body-fluid composition in normal and hypertensive man.
    Clinical science (London, England : 1979), 1982, Volume: 62, Issue:1

    Topics: Adult; Aged; Aldosterone; Body Fluids; Body Water; Erythrocyte Volume; Extracellular Space; Humans;

1982
[A case of glucocorticoid responsive aldosteronism (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1981, Oct-10, Volume: 70, Issue:10

    Topics: Aldosterone; Dexamethasone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertensio

1981
Rise in plasma concentration of aldosterone during long-term angiotensin II suppression.
    The Journal of endocrinology, 1981, Volume: 91, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Captopril; Depression, Chemical; Female; Humans; Hypertension; M

1981
Inter-relationship of sympathetic nervous system and renin-angiotensin-aldosterone system in three renin subgroups of borderline and persistent essential hypertension.
    Clinical and experimental hypertension, 1981, Volume: 3, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Dopamine beta-Hydroxylase; Female; Furo

1981
Reversal of glucose-induced hyperkalemia by sodium restriction in "normaldosteronemic" diabetes mellitus.
    Endokrinologie, 1981, Volume: 78, Issue:2-3

    Topics: Adult; Aged; Aldosterone; Blood Glucose; Diabetes Complications; Diet, Sodium-Restricted; Female; Gl

1981
Circadian changes in plasma renin activity and plasma aldosterone concentration in one-kidney hypertensive rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 169, Issue:1

    Topics: Aldosterone; Animals; Blood Pressure; Circadian Rhythm; Constriction; Hypertension; Kidney; Male; Ra

1982
Simple screening procedure for the diagnosis of primary aldosteronism.
    Acta medica Scandinavica, 1981, Volume: 210, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hype

1981
Antihypertensive effect of the oral angiotensin I-converting enzyme inhibitor in long-term treatment of hypertensive patients.
    Japanese heart journal, 1981, Volume: 22, Issue:6

    Topics: Adult; Aged; Aldosterone; Bradykinin; Captopril; Female; Humans; Hypertension; Hypertension, Maligna

1981
Renin, the heart and hypertension.
    The American journal of cardiology, 1982, Apr-21, Volume: 49, Issue:6

    Topics: Aldosterone; Captopril; Heart Failure; Humans; Hypertension; Renin

1982
Comparison of the hormonal and renal effects of captopril in severe essential and renovascular hypertension.
    The American journal of cardiology, 1982, Apr-21, Volume: 49, Issue:6

    Topics: Aldosterone; Blood Pressure; Blood Volume; Captopril; Humans; Hypertension; Hypertension, Renal; Hyp

1982
Changes of the intralymphocytic sodium concentration after acute and chronic captopril administration.
    The American journal of cardiology, 1982, Apr-21, Volume: 49, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Humans; Hypertension; Lymphocytes; Middle Aged; Potas

1982
Role of sympathetic nervous system activity in the blood pressure response to long-term captopril therapy in severely hypertensive patients.
    The American journal of cardiology, 1982, Apr-21, Volume: 49, Issue:6

    Topics: Aldosterone; Blood Pressure; Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hype

1982
Increase in plasma aldosterone during prolonged captopril treatment.
    The American journal of cardiology, 1982, Apr-21, Volume: 49, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Humans; Hypertension; Hypertension, Renal; Hypertensi

1982
Comparison of antihypertensive and hormonal effects of captopril and propranolol at rest and during exercise.
    The American journal of cardiology, 1982, Apr-21, Volume: 49, Issue:6

    Topics: Aldosterone; Blood Pressure; Captopril; Drug Therapy, Combination; Humans; Hypertension; Male; Physi

1982
Renin as a risk factor for atherogenesis. Part 3. Effects of hypercholesterolemia, hyporeninemia and one-kidney-one clip hypertension in the rabbit.
    Atherosclerosis, 1982, Volume: 42, Issue:2-3

    Topics: Aldosterone; Animals; Arteriosclerosis; Blood Pressure; Blood Urea Nitrogen; Body Weight; Cholestero

1982
[Dopamine-beta-hydroxylase activity, aldosterone level, and plasma renin activity in patients with essential hypertension during exposure to physical load (author's transl)].
    Bratislavske lekarske listy, 1982, Volume: 77, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Dopamine beta-Hydroxylase; Humans; Hypertension; Male; Physical Exer

1982
Aldosterone in sustained essential hypertension.
    Clinical endocrinology, 1982, Volume: 16, Issue:1

    Topics: Adult; Aldosterone; Extracellular Space; Humans; Hypertension; Inulin; Liver Circulation; Male; Midd

1982
A vasodilator that avoids renin stimulation and fluid retention: antihypertensive treatment with trimazosin.
    Clinical pharmacology and therapeutics, 1982, Volume: 31, Issue:5

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Body Fluids; Female; Heart Rate;

1982
Effect of angiotensin converting enzyme inhibitor on serum aldosterone and potassium level.
    Japanese heart journal, 1982, Volume: 23, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Captopril; Diet, Sodium-Restricted; Female; Humans; Hypert

1982
[The renin-aldosterone profile in hypertension].
    Kardiologiia, 1982, Volume: 22, Issue:3

    Topics: Adult; Aldosterone; Circadian Rhythm; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-

1982
[Blood pressure, renin angiotensin aldosterone system and other cardiovascular risk factors in children of essential hypertensives (author's transl)].
    Klinische Wochenschrift, 1982, Volume: 60, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Blood Glucose; Blood Pressure; Child; Child, Preschool; Cholesterol;

1982
19-hydroxyandrostenedione as a new hypertensinogenic agent.
    Journal of steroid biochemistry, 1982, Volume: 16, Issue:2

    Topics: Aldosterone; Androstenedione; Animals; Blood Pressure; Corticosterone; Desoxycorticosterone; Hyperte

1982
The renin-angiotensin-aldosterone system and hypertension in primary hyperparathyroidism.
    Metabolism: clinical and experimental, 1982, Volume: 31, Issue:6

    Topics: Adult; Aged; Aldosterone; Female; Furosemide; Humans; Hyperparathyroidism; Hypertension; Male; Middl

1982
Effect of dietary sodium intake on the metabolism of prostaglandins in the kidney in hypertensive patients.
    Prostaglandins, leukotrienes, and medicine, 1982, Volume: 8, Issue:3

    Topics: Adult; Aldosterone; Diet; Female; Humans; Hypertension; Male; Middle Aged; Prostaglandins; Renin; So

1982
Sodium sensitivity and resistance in normotensive humans.
    The American journal of medicine, 1982, Volume: 72, Issue:5

    Topics: Adult; Age Factors; Aged; Aldosterone; Black People; Blood Pressure; Female; Humans; Hypertension; M

1982
Hormonal changes associated with hypertension in neoplasia-induced hypercalcemia.
    The American journal of physiology, 1982, Volume: 242, Issue:5

    Topics: Aldosterone; Animals; Calcium; Hormones; Hypercalcemia; Hypertension; Leydig Cell Tumor; Male; Norep

1982
Exchangeable sodium and saralasin-blocking, plasma renin and aldosterone in pre- and postoperative young patients with aortic coarctation.
    European heart journal, 1982, Volume: 3, Issue:2

    Topics: Adolescent; Aldosterone; Angiotensin II; Aortic Coarctation; Child; Humans; Hypertension; Natriuresi

1982
Discrimination of renovascular from essential hypertension by converting enzyme inhibition with an orally active compound.
    Acta clinica Belgica, 1982, Volume: 37, Issue:1

    Topics: Administration, Oral; Adult; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Diagnosis, Diffe

1982
Renal function and hemodynamic studies in low- and normal-renin essential hypertension.
    Archives of internal medicine, 1982, Volume: 142, Issue:7

    Topics: Adult; Aldosterone; Glomerular Filtration Rate; Humans; Hypertension; Inulin; Kidney; Male; Metaboli

1982
Response of the systemic pulmonary circulation to labetalol at rest and during exercise.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:1 Suppl

    Topics: Adult; Aldosterone; Ethanolamines; Female; Hemodynamics; Humans; Hypertension; Labetalol; Male; Phen

1982
Captopril treatment: inter-dose variations in renin, angiotensins I and II, aldosterone and blood pressure.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Female; Hu

1982
Hormonal pattern during development of hypertension in spontaneously hypertensive rats (SHR).
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:6

    Topics: Aldosterone; Animals; Blood Pressure; Dinoprostone; Dopamine; Hormones; Hypertension; Norepinephrine

1982
Aldosterone responsiveness to angiotensin II after sodium restriction in subjects with low renin essential hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:6

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hyperte

1982
The role of urinary PGE2 and renin-angiotensin-aldosterone system in the pathogenesis of essential hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:6

    Topics: Adult; Aldosterone; Creatinine; Dinoprostone; Female; Furosemide; Glomerular Filtration Rate; Humans

1982
[Endocrinological analysis of etiology of essential hypertension (author's transl)].
    Horumon to rinsho. Clinical endocrinology, 1982, Volume: 30, Issue:4

    Topics: Adult; Aged; Aging; Aldosterone; Catecholamines; Humans; Hypertension; Middle Aged; Renin; Renin-Ang

1982
Relation of arterial pressure with body sodium, body potassium and plasma potassium in essential hypertension.
    Clinical science (London, England : 1979), 1982, Volume: 63, Issue:3

    Topics: Adult; Age Factors; Aldosterone; Angiotensin II; Blood Pressure; Body Surface Area; Body Weight; Hum

1982
[The renin-aldosterone system in the diagnosis of essential hypertension].
    Harefuah, 1982, Feb-15, Volume: 102, Issue:4

    Topics: Adult; Aldosterone; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin

1982
[A decreased metabolic clearance rate of aldosterone in low-renin essential hypertension (author's transl)].
    Nihon Jinzo Gakkai shi, 1982, Volume: 24, Issue:1

    Topics: Adult; Aldosterone; Humans; Hypertension; Metabolic Clearance Rate; Middle Aged; Renin

1982
An unusual case of hypertension with hypokalaemia.
    Acta cardiologica, 1982, Volume: 37, Issue:2

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Hypokalemia; Renin

1982
Dopaminergic regulation of circadian rhythms of blood pressure, renin and aldosterone in essential hypertension.
    Cardiovascular research, 1982, Volume: 16, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Bromocriptine; Circadian Rhythm; Dopamine; Humans; Hypertension;

1982
Primary aldosteronism associated with a primary double cancer of the thyroid and rectum: report of a case.
    Endocrinologia japonica, 1981, Volume: 28, Issue:6

    Topics: Adenocarcinoma; Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hyperten

1981
Low-renin, low-aldosterone hypertension and abnormal cortisol metabolism in a 19-month-old child.
    Hormone research, 1982, Volume: 16, Issue:2

    Topics: Aldosterone; Cortisone; Dexamethasone; Follow-Up Studies; Furosemide; Humans; Hydrocortisone; Hypert

1982
[Renin-angiotensin-aldosterone system and glucocorticoids in arterial hypertension].
    Sovetskaia meditsina, 1982, Issue:5

    Topics: Aldosterone; Glucocorticoids; Humans; Hydrocortisone; Hypertension; Hypertension, Renovascular; Pyel

1982
Blood pressure in relation to the renin-angiotensin-aldosterone system.
    Acta medica Scandinavica, 1982, Volume: 211, Issue:5

    Topics: Aldosterone; Analysis of Variance; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Middl

1982
Direct radioimmunoassays for "aldosterone" and "18-hydroxycorticosterone" in unprocessed urine, and their use in screening to distinguish primary aldosteronism from hypertension.
    Clinical chemistry, 1982, Volume: 28, Issue:3

    Topics: 18-Hydroxycorticosterone; Aldosterone; Corticosterone; Diagnosis, Differential; Female; Humans; Hype

1982
[Fundamental and clinical studies on measurement of serum aldosterone by solid phase (author's transl)].
    Horumon to rinsho. Clinical endocrinology, 1982, Volume: 30, Issue:1

    Topics: Adult; Aged; Aldosterone; Humans; Hypertension; Middle Aged; Radioimmunoassay; Reagent Kits, Diagnos

1982
[Role of the angiotensin-aldosterone mechanism in the formation of Pulmonogenic arterial hypertension].
    Klinicheskaia meditsina, 1982, Volume: 60, Issue:1

    Topics: Aldosterone; Angiotensin I; Angiotensins; Chronic Disease; Humans; Hypertension; Hypertension, Pulmo

1982
Role of adrenal steroidogenesis in etiology of hypertension in the spontaneously hypertensive rat.
    Endocrinology, 1982, Volume: 111, Issue:1

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Glands; Aging; Aldosterone; Animals; Body Weight; Corticoste

1982
The vasoconstriction-volume spectrum in normotension and in the pathogenesis of hypertension.
    Federation proceedings, 1982, Volume: 41, Issue:8

    Topics: Aldosterone; Animals; Blood Pressure; Blood Volume; Dogs; Humans; Hypertension; Hypertension, Malign

1982
Parallel adrenal and renal abnormalities in young patients with essential hypertension.
    The American journal of medicine, 1982, Volume: 72, Issue:6

    Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Diuresis; Female; Hemod

1982
[Hypokalemic myopathy in arterial hypertension].
    Minerva medica, 1982, Sep-15, Volume: 73, Issue:35

    Topics: Adult; Aged; Aldosterone; Diuretics; Fluprednisolone; Glycyrrhiza; Humans; Hypertension; Hypokalemia

1982
Allantoxanamide-induced myocardial necrosis in Sprague-Dawley vs spontaneously hypertensive rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 170, Issue:4

    Topics: Aldosterone; Animals; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Corticosterone; Female; He

1982
Acromegaly and hypertension: role of the renin-angiotensin-aldosterone system.
    Acta endocrinologica, 1982, Volume: 100, Issue:4

    Topics: Acromegaly; Adult; Aged; Aldosterone; Blood Pressure; Female; Furosemide; Humans; Hypertension; Male

1982
Proceedings of the symposium Mineralocorticoids in Essential and Secondary Hypertension. Newport Beach, California, February 28, 1982.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: Aldosterone; Animals; Humans; Hypertension; Mineralocorticoids

1982
The mineralocorticoid hormone pathways in hypertension with hyperaldosteronism.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: 18-Hydroxydesoxycorticosterone; Adenoma; Aldosterone; Corticosterone; Desoxycorticosterone; Hydrocor

1982
Hypersecretion of a new corticosteroid, 18-hydroxycortisol in two types of adrenocortical hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: Adenoma; Adrenal Cortex; Aldosterone; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension

1982
Aldosterone, sodium and potassium in essential hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Potassium; Reference Val

1982
["Volume-dependent" form of hypertension].
    Kardiologiia, 1982, Volume: 22, Issue:9

    Topics: Aldosterone; Blood Pressure; Body Water; Cardiac Output; Extracellular Space; Female; Humans; Hypert

1982
[Diagnosis and surgical treatment of adrenal forms of symptomatic arterial hypertension].
    Khirurgiia, 1982, Issue:9

    Topics: Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Glucocortic

1982
The Yucatan miniature swine: an improved pig model for the study of desoxycorticosterone-acetate (DOCA) and aldosterone hypertension.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 171, Issue:1

    Topics: Aldosterone; Animals; Desoxycorticosterone; Disease Models, Animal; Hypertension; Swine

1982
Altered arterial ion transport and its reversal in aldosterone hypertensive rat.
    The American journal of physiology, 1982, Volume: 243, Issue:6

    Topics: Aldosterone; Animals; Arteries; Biological Transport, Active; Blood Pressure; Hypertension; Ions; Ma

1982
Differences in adrenal cholesterol, ascorbic acid, circulating corticosterone and aldosterone during the onset of hypertension in SHR vs WKy rats.
    Cardiovascular research, 1982, Volume: 16, Issue:10

    Topics: Adrenal Glands; Aldosterone; Animals; Ascorbic Acid; Cholesterol; Corticosterone; Hypertension; Male

1982
Plasma aldosterone concentrations in neonatal spontaneously hypertensive rats.
    Life sciences, 1982, Dec-13, Volume: 31, Issue:24

    Topics: Age Factors; Aldosterone; Animals; Animals, Newborn; Hypertension; Rats

1982
[Effects of passive semiorthostatic cardiopulmonary hematic centralization (by immersion in water) on hydrosaline elimination and on the renin-angiotensin-aldosterone system in essential hypertension].
    Giornale italiano di cardiologia, 1982, Volume: 12, Issue:10

    Topics: Adolescent; Adult; Aged; Aldosterone; Cardiovascular System; Creatinine; Diuresis; Humans; Hypertens

1982
Long term spironolactone and the adrenal cortex in essential hypertension.
    Clinical endocrinology, 1980, Volume: 13, Issue:3

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex; Adult; Aged; Aldosterone; Cosyntropin; Female; Human

1980
Hypersensitivity of spontaneously hypertensive rats (SHR) to heat, ether, and immobilization.
    Endocrinology, 1981, Volume: 108, Issue:5

    Topics: Aldosterone; Animals; Blood Glucose; Corticosterone; Ether; Ethyl Ethers; Female; Growth Hormone; Ho

1981
Changes in the morphology and location of arterial lesions in virgin and breeder Sprague-Dawley and spontaneously hypertensive rats (SHR) to adrenal regeneration hypertension.
    Paroi arterielle, 1980, Volume: 6, Issue:2

    Topics: Adrenal Glands; Aldosterone; Animals; Aorta; Aortic Diseases; Arterioles; Arteriosclerosis; Blood Pr

1980
Circadian rhythm of circulating aldosterone in spontaneously hypertensive rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1981, Volume: 167, Issue:2

    Topics: Aldosterone; Animals; Circadian Rhythm; Female; Hypertension; Male; Rats; Sex Factors

1981
[Determination of urinary 3 alpha, 5 beta-tetrahydroaldosterone as a parameter of aldosterone secretion in hypersensitive patients (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1981, Jan-20, Volume: 57, Issue:1

    Topics: Aldosterone; Humans; Hypertension; Radioimmunoassay

1981
[14C-aldosterone binding by plasma proteins in adolescents with primary arterial hypertension].
    Kardiologiia, 1981, Volume: 21, Issue:7

    Topics: Adolescent; Aldosterone; Blood Proteins; Carbon Radioisotopes; Humans; Hyperaldosteronism; Hypertens

1981
Blood levels of ethynylestradiol, caffeine, aldosterone and desoxycorticosterone in hypertensive oral contraceptive users.
    Contraception, 1981, Volume: 23, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Caffeine; Contraceptives, Oral; Desoxycorticosterone

1981
Mineralocorticoid and hypertensive effects of 19-nor-progesterone.
    Endocrinology, 1981, Volume: 109, Issue:4

    Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Body Temperature; Body Weight; Drinking; Female

1981
[Preoperative management of 461 hypertensive women].
    Ginecologia y obstetricia de Mexico, 1981, Volume: 49, Issue:292

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Genital Diseases, Female;

1981
Cyproheptadine in idiopathic aldosteronism.
    The New England journal of medicine, 1981, Nov-12, Volume: 305, Issue:20

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cyproheptadine; Dexamethasone; Drug Synergism; Humans

1981
Propranolol-induced alterations in the pathophysiology of spontaneously hypertensive rats.
    Life sciences, 1981, Oct-05, Volume: 29, Issue:14

    Topics: Aging; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Corticosterone; F

1981
[Excretion of free aldosterone fraction in adolescents with hypertension].
    Pediatriia, 1981, Issue:9

    Topics: Adolescent; Aldosterone; Child; Glucuronates; Humans; Hypertension

1981
The role of aldosterone in the development of hypertension in spontaneously hypertensive rats.
    Endocrinology, 1981, Volume: 109, Issue:6

    Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Creatinine; Hypertension; Kidney; Male; Potassi

1981
[Estimation of the urinary aldosterone (author's transl)].
    Radioisotopes, 1981, Volume: 30, Issue:7

    Topics: Aldosterone; Humans; Hypertension; Kidney Diseases; Liver Diseases; Radioimmunoassay; Reagent Kits,

1981
[A direct radioimmunoassay determination of plasma aldosterone concentration in normal subjects and patients with hypertension or renal disease using 125I-labeled ligand (ALDOCTK-125 Kit) (author's transl)].
    Fukuoka igaku zasshi = Hukuoka acta medica, 1981, Volume: 72, Issue:11

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Radioimmunoass

1981
Characteristics of aldosterone binding in human plasma.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:1

    Topics: Aldosterone; Carrier Proteins; Humans; Hydrocortisone; Hypertension; Kinetics; Transcortin

1980
Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:4

    Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Bendroflumethiazide; Bicarbonates; Blood Pressure; Di

1980
Primary aldosteronism.
    British medical journal, 1980, Mar-08, Volume: 280, Issue:6215

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Posture

1980
Effects of propranolol on aldosterone plasma concentration and aldosterone metabolic clearance in hypertensive patients.
    The Journal of laboratory and clinical medicine, 1980, Volume: 95, Issue:5

    Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Metabolic Clearance Rate; Mi

1980
[Measurement of percent uptake in the adrenal glands with 131I-adosterol (author's transl)].
    Kaku igaku. The Japanese journal of nuclear medicine, 1980, Volume: 17, Issue:2

    Topics: Adosterol; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Cushing Syndrome; Humans; Hypertens

1980
Hyperaldosteronism, hyperparathyroidism, medullary sponge kidneys, and hypertension.
    JAMA, 1980, Sep-19, Volume: 244, Issue:12

    Topics: Adenoma; Adult; Aldosterone; Blood Pressure; Female; Humans; Hyperaldosteronism; Hyperparathyroidism

1980
[A simple method for measuring aldosterone secretion rate using 125I-aldosterone (authors' transl)].
    Nihon Naibunpi Gakkai zasshi, 1980, Aug-20, Volume: 56, Issue:8

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hyperthyroidism; Iodine Radioisotopes; Radioi

1980
Deoxycorticosterone and aldosterone clearance and binding in normal and hypertensive man.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:5

    Topics: Adult; Aldosterone; Desoxycorticosterone; Humans; Hypertension; Metabolic Clearance Rate; Middle Age

1980
[Role of mineralocorticoid regulation of vascular reactivity in the arterial pressure reaction to increased salt uptake in healthy persons].
    Kardiologiia, 1980, Volume: 20, Issue:9

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Vessels; Dose-Response Relationship, Drug;

1980
[Hypotensive effect of spironolactone in patients with essential hypertension and aldosterone regulation disorders].
    Die Medizinische Welt, 1980, Aug-08, Volume: 31, Issue:31-32

    Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Spironolactone

1980
Increased 18-hydroxycorticosterone responses to frusemide in essential hypertension.
    Clinical endocrinology, 1980, Volume: 12, Issue:5

    Topics: 18-Hydroxycorticosterone; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Corticosterone; Female

1980
Regulation of serum-progesterone in patients with essential hypertension.
    Acta endocrinologica, 1980, Volume: 95, Issue:2

    Topics: Adult; Aged; Aldosterone; Circadian Rhythm; Diet, Sodium-Restricted; Humans; Hypertension; Hypertens

1980
Urinary tetrahydroaldosterone and aldosterone-18-glucuronide excretion in white and black normal subjects and hypertensive patients.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 52, Issue:2

    Topics: Adult; Aldosterone; Black People; Diet; Female; Glucuronates; Humans; Hyperaldosteronism; Hypertensi

1981
Circadian blood pressure variation versus renal function.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1995, Volume: 26, Issue:5

    Topics: Aldosterone; Black People; Blood Pressure; Circadian Rhythm; Creatinine; Heart Rate; Humans; Hyperte

1995
Ca(2+)-dependent K+ current in arterial smooth muscle cells from aldosterone-salt hypertensive rats.
    The American journal of physiology, 1995, Volume: 269, Issue:4 Pt 2

    Topics: Aldosterone; Animals; Arteries; Caffeine; Calcium; Calcium Channel Blockers; Charybdotoxin; Electric

1995
[Conceptual basis and diagnosis of primary hyperaldosteronism].
    Archives des maladies du coeur et des vaisseaux, 1995, Volume: 88, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hyper

1995
Biological determinants of aldosterone-induced cardiac fibrosis in rats.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:6 Pt 1

    Topics: Aldosterone; Animals; Blotting, Northern; Collagen; Fibrosis; Heart; Histocytochemistry; Hypertensio

1995
[Conn's adenoma. Diagnostic and prognostic value of the measurement of potassium, renin, aldosterone levels and the aldosterone/renin ratio].
    Presse medicale (Paris, France : 1983), 1995, Sep-23, Volume: 24, Issue:27

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potassium;

1995
[Hyperaldosteronism sensitive to dexamethasone with adrenal adenoma. Clinical, biological and genetic study].
    Presse medicale (Paris, France : 1983), 1995, Sep-23, Volume: 24, Issue:27

    Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Dexamethasone; Fem

1995
Effect of the new calcium antagonist (+/-)-(R*)-3-[(R*)-1-benzyl-3- piperidyl] methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5- pyridinedicarboxylate hydrochloride (KW-3049) on cardiac hypertrophy in spontaneously hypertensive rats.
    The Journal of toxicological sciences, 1993, Volume: 18 Suppl 3

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegal

1993
Hormonal, renal, and metabolic alterations during hypertension induced by chronic inhibition of NO in rats.
    The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 2

    Topics: Aldosterone; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Creatinine; Diuresis; Do

1994
Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome.
    Nature genetics, 1995, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Alleles; Amino Acid Sequence; Animals; Base Sequence; Codon; Epithel

1995
Central obesity and hypertension: pathophysiologic role of renal haemodynamics and function.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1995, Volume: 19, Issue:6

    Topics: Adult; Albuminuria; Aldosterone; Body Constitution; Body Mass Index; Cardiac Output; Female; Glomeru

1995
Left ventricular mass in hereditary human hypertension: glucocorticoid-suppressible hyperaldosteronism.
    Journal of hypertension, 1995, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Child; Female; Genotype; Glucocorticoids; Humans; Hy

1995
In vivo pharmacology of L-159,913, a new highly potent and selective nonpeptide angiotensin II receptor antagonist.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1995, Volume: 17, Issue:6

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Bip

1995
Phorbol ester-stimulated 6-keto-prostaglandin F1 alpha in aortas from control and aldosterone-salt rats.
    Journal of hypertension, 1995, Volume: 13, Issue:7

    Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Alkaloids; Animals; Aorta; Calcium; Dose-Response Relatio

1995
[Evaluation of the efficacy and safety of monotherapy for significant essential hypertension in adolescents with use of enalapril].
    Pediatria polska, 1995, Volume: 70, Issue:2

    Topics: Adolescent; Aldosterone; Child; Echocardiography; Enalapril; Evaluation Studies as Topic; Female; Ga

1995
Hypertension in cyclosporin A-treated patients is independent of circulating endothelin levels.
    Journal of internal medicine, 1995, Volume: 238, Issue:1

    Topics: Adult; Aldosterone; Arthritis, Rheumatoid; Atrial Natriuretic Factor; Blood Pressure; Cyclosporine;

1995
Attenuated Ca2+ response to acetylcholine in endothelial cells from aorta of aldosterone-salt hypertensive rats.
    American journal of hypertension, 1995, Volume: 8, Issue:4 Pt 1

    Topics: Acetylcholine; Aldosterone; Animals; Arginine; Calcium; Endothelium, Vascular; Fura-2; Hypertension;

1995
Acute effects of flosequinan (BTS 49465) in untreated moderate to severe hypertension.
    Journal of human hypertension, 1995, Volume: 9, Issue:5

    Topics: Administration, Oral; Adult; Aldosterone; Epinephrine; Female; Hemodynamics; Humans; Hypertension; M

1995
The Bergen Blood Pressure Study: inappropriately low levels of circulating atrial natriuretic peptide in offspring of hypertensive families.
    Blood pressure, 1994, Volume: 3, Issue:4

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Catecholamines; Family; Female; Human

1994
Glucocorticoids but not mineralocorticoids modulate endothelin-1 and angiotensin II binding in SHR vascular smooth muscle cells.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 52, Issue:3

    Topics: Aldosterone; Androstanols; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compo

1995
The role of potassium in postural hypotension: electrolytes and neurohumoral factors in elderly hypertensive patients using diuretics.
    Journal of internal medicine, 1995, Volume: 237, Issue:4

    Topics: Aged; Aged, 80 and over; Aldosterone; Atrial Natriuretic Factor; Case-Control Studies; Cross-Section

1995
11 beta-Hydroxysteroid dehydrogenase and its inhibitors in hypertensive pregnancy.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:4 Pt 1

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Blood Pressure; Female; Humans; Hydrocort

1995
Angiotensin and bradykinin peptides in the TGR(mRen-2)27 rat.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:5

    Topics: Aldosterone; Amino Acid Sequence; Angiotensin II; Animals; Animals, Genetically Modified; Bradykinin

1995
Angiotensin peptides in spontaneously hypertensive and normotensive Donryu rats.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:5

    Topics: Adipose Tissue, Brown; Adrenal Glands; Aldosterone; Angiotensins; Animals; Brain Chemistry; Hyperten

1995
Renal and adrenal sparing surgery for patients with primary aldosteronism and primary reninoma.
    The Journal of urology, 1995, Volume: 153, Issue:6

    Topics: Adenocarcinoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Humans

1995
Aldosterone and testosterone producing adrenal adenoma in childhood.
    Journal of endocrinological investigation, 1995, Volume: 18, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Child; Humans; Hypertension; Male; Nephrocalcinosis;

1995
Clinical evidence for an association between left ventricular geometric adaptation and extracardiac target organ damage in essential hypertension.
    Journal of hypertension, 1995, Volume: 13, Issue:1

    Topics: Aldosterone; Catecholamines; Cholesterol; Creatinine; Female; Humans; Hypertension; Hypertrophy, Lef

1995
Atrial natriuretic peptide and antihypertensive action due to beta-blockade in essential hypertensive patients.
    Angiology, 1995, Volume: 46, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor;

1995
Renal, endocrine and vascular effects of atrial natriuretic peptide in a novel vasopressin-deficient genetically hypertensive strain of rat.
    Experimental physiology, 1995, Volume: 80, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Disease Models, Ani

1995
Aldosterone and Hypertension. Proceedings of a satellite symposium to the 15th International Society of Hypertension Congress. Lorne, Victoria, Australia, March 17-19, 1994.
    Steroids, 1995, Volume: 60, Issue:1

    Topics: Aldosterone; Animals; Blood Pressure; History, 20th Century; Humans; Hyperaldosteronism; Hypertensio

1995
Differences in temperature-sensitive receptor binding of glucocorticoids in spontaneously hypertensive and normotensive Wistar-Kyoto rats.
    Steroids, 1995, Volume: 60, Issue:1

    Topics: Aldosterone; Animals; Corticosterone; Dexamethasone; Hypertension; Male; Radioligand Assay; Rats; Ra

1995
Exaggerated blood pressure response to angiotensin II in patients with Cushing's syndrome due to adrenocortical adenoma.
    European journal of endocrinology, 1994, Volume: 131, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Cu

1994
Screening of a population of young hypertensives for primary hyperaldosteronism.
    Journal of human hypertension, 1994, Volume: 8, Issue:9

    Topics: Adult; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Middle Aged; Renin

1994
Nonmodulating trait may precede the development of hypertension.
    American journal of hypertension, 1994, Volume: 7, Issue:9 Pt 1

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Dopamine; Humans; Hypertension; Infusions,

1994
Renin-sodium profile and renal prostaglandins in the pathogenesis of systemic arterial hypertension in blacks.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1994, Volume: 84, Issue:8 Pt 1

    Topics: Adult; Aldosterone; Black People; Female; Humans; Hypertension; Kidney; Potassium; Prostaglandins; R

1994
Hypertension and the mineralocorticoid receptor in the brain.
    Annals of the New York Academy of Sciences, 1994, Nov-30, Volume: 746

    Topics: Adrenalectomy; Aldosterone; Amiloride; Animals; Blood Pressure; Brain; Cerebral Ventricles; Hippocam

1994
Renin and aldosterone are higher and the hyperinsulinemic effect of salt restriction greater in subjects with risk factors clustering.
    American journal of hypertension, 1994, Volume: 7, Issue:10 Pt 1

    Topics: Adult; Aldosterone; Anthropometry; Blood Pressure; Cluster Analysis; Coronary Disease; Diet; Diet, S

1994
Relationships among plasma aldosterone, high-density lipoprotein cholesterol, and insulin in humans.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Cholesterol, HDL; Female; Humans; Hypertension; Insulin; Male; M

1995
The impaired control of plasma renin activity in hypertensive patients with end-stage renal disease due to chronic glomerulonephritis.
    Clinical nephrology, 1994, Volume: 42, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Glomerulonephritis; Humans; H

1994
19-Hydroxyandrostenedione amplifies the hypertensive action of mineralocorticoids in rats.
    The Journal of endocrinology, 1993, Volume: 138, Issue:1

    Topics: Aldosterone; Androstenedione; Animals; Blood Pressure; Desoxycorticosterone; Dose-Response Relations

1993
Role of glucocorticoid in the development of glycyrrhizin-induced hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1994, Volume: 16, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Blood Pr

1994
Angiotensin II type 1 receptor messenger RNA levels in human blood cells of patients with primary and secondary hypertension: reference to renin profile.
    Journal of hypertension, 1994, Volume: 12, Issue:11

    Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Base Sequence; Blood Platelets; Blotting, Northe

1994
Resolution of posttransplant hypertension after liver transplantation despite impaired glomerular filtration.
    Journal of the American Society of Nephrology : JASN, 1994, Volume: 5, Issue:5

    Topics: Adult; Aldosterone; Antihypertensive Agents; Epoprostenol; Female; Glomerular Filtration Rate; Hemod

1994
Artificial mutations in P450c11AS (aldosterone synthase) can increase enzymatic activity: a model for low-renin hypertension?
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:3

    Topics: Aldosterone; Animals; Base Sequence; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme System; Hyper

1995
A new subset of mineralocorticoid hypertension with excess of 21-deoxyaldosterone and Kelly's-M1 steroid: clinical and morphological findings.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hypertension; Immunohistochemi

1995
The serum angiotensinogen concentration and variants of the angiotensinogen gene in white and black children.
    The Journal of clinical investigation, 1995, Volume: 95, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Alleles; Angiotensinogen; Base Sequence; Black People; Blood Pressur

1995
Role of the renin-angiotensin system in arterial hypertension secondary to acute unilateral urinary obstruction.
    Renal failure, 1994, Volume: 16, Issue:6

    Topics: Aldosterone; Animals; Blood Pressure; Captopril; Disease Models, Animal; Dogs; Hypertension; Renin;

1994
Role of 21-deoxyaldosterone in human hypertension.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 50, Issue:5-6

    Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Female; Humans; Hyperaldos

1994
High incidence of primary aldosteronism in 199 patients referred with hypertension.
    Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Female; Humans; Hyperaldosteronism; Hyperte

1994
[Effect of captopril on adrenal gluco- and mineral-corticoid functions in the treatment of patients with hypertension].
    Kardiologiia, 1993, Volume: 33, Issue:4

    Topics: 11-Hydroxycorticosteroids; Adrenal Glands; Adult; Aged; Aldosterone; Captopril; Female; Humans; Hype

1993
Zona glomerulosa of the adrenal gland in a transgenic strain of rat: a morphologic and functional study.
    Cell and tissue research, 1994, Volume: 278, Issue:1

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Animals, Genetically Modified; Ce

1994
[A case of idiopathic hyperaldosteronism with normal plasma aldosterone concentrations for 5 years after onset: a 12-year follow-up study].
    Nihon Naibunpi Gakkai zasshi, 1994, May-20, Volume: 70, Issue:4

    Topics: Aldosterone; Diagnosis, Differential; Follow-Up Studies; Furosemide; Humans; Hyperaldosteronism; Hyp

1994
The association between salt sensitivity of blood pressure and some polymorphic factors.
    Journal of hypertension, 1994, Volume: 12, Issue:7

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; DNA Transposable Elements; Drug R

1994
The role of endogenous digitalis-like factor in blood pressure regulation in essential hypertension.
    Wiener klinische Wochenschrift, 1994, Volume: 106, Issue:16

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Blood Proteins; Cardenolides; Digoxin

1994
The CSF aldosterone in brain tumors with brain edema.
    Acta neurochirurgica. Supplementum, 1994, Volume: 60

    Topics: Adolescent; Adult; Aged; Aldosterone; Astrocytoma; Blood-Brain Barrier; Brain Edema; Brain Neoplasms

1994
Effect of central amiloride infusion on mineralocorticoid hypertension.
    The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 1

    Topics: Aldosterone; Amiloride; Animals; Brain; Carbenoxolone; Diet; Hypertension; Injections, Intraventricu

1994
Adrenal adenoma with primary aldosteronism in a child: a case report.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1994, Volume: 54, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Child; Female; Humans; Hyperaldosteronism; Hypertensi

1994
[Endocrinological and imaging analyses of adrenal incidentalomas with hypertension and/or diabetes mellitus].
    Nihon Naibunpi Gakkai zasshi, 1994, Oct-20, Volume: 70, Issue:8

    Topics: 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Aged; Aldosterone; Carcinoma; Catecholamines; Cus

1994
Cushing's disease: evaluation of mineralocorticoid-induced hypertension.
    Internal medicine (Tokyo, Japan), 1993, Volume: 32, Issue:10

    Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Corticosterone; Cushing Sy

1993
Effect of an angiotensin II receptor antagonist, CV-11974, and its prodrug, TCV-116, on production of aldosterone.
    European journal of pharmacology, 1994, Feb-21, Volume: 253, Issue:1-2

    Topics: Administration, Oral; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin III; Ang

1994
Hypertension induced by a nonpressor dose of angiotensin II in kininogen-deficient rats.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Heart Rate; Hypertension; Kininogens; Kinins;

1994
Increased cardiac types I and III collagen mRNAs in aldosterone-salt hypertension.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:1

    Topics: Aldosterone; Animals; Collagen; Gene Expression; Hypertension; Male; Myocardium; Rats; Rats, Wistar;

1994
[Changes in humoral pressor and depressor factors in essential hypertension during lisinopril therapy].
    Vnitrni lekarstvi, 1994, Volume: 40, Issue:5

    Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Female; Humans; Hypertension; Kallikreins; Lisin

1994
The renal functional reserve in recently diagnosed essential hypertension.
    Clinical nephrology, 1994, Volume: 41, Issue:4

    Topics: Adult; Albuminuria; Aldosterone; Amino Acids; Catecholamines; Creatinine; Humans; Hypertension; Kidn

1994
[Primary amenorrhea and arterial hypertension in a case of 17 alpha-hydroxylase deficiency].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1994, Volume: 23, Issue:2

    Topics: Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Amenorrhea; Corticosterone; Desoxycorticosteron

1994
Unilateral adrenal hypersecretion of both aldosterone and cortisol in two first cousins with a syndrome of mineralocorticoid excess but without signs of hypercortisolism.
    Endocrine research, 1994, Volume: 20, Issue:2

    Topics: Adrenal Glands; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hyperaldosteronism; Hyperplasia;

1994
Role of insulin and norepinephrine in the hypertension of obesity.
    American journal of hypertension, 1994, Volume: 7, Issue:5

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Insulin; Male; Norepinephrine; Obesity; Renin; Wei

1994
Effect of insulin on sodium reabsorption in hypertensive patients.
    American journal of hypertension, 1994, Volume: 7, Issue:5

    Topics: Absorption; Adult; Aldosterone; Blood Glucose; Blood Pressure; Glucose Clamp Technique; Humans; Hype

1994
[Possible influence of hemodynamic and neurohormonal factors on the heart's response to arterial hypertension].
    Cardiologia (Rome, Italy), 1994, Volume: 39, Issue:4

    Topics: Adult; Aldosterone; Cardiomegaly; Female; Heart; Hemodynamics; Humans; Hypertension; Linear Models;

1994
Abnormalities in the renin-angiotensin-aldosterone system in normotensive subjects with a positive family history of hypertension.
    European journal of endocrinology, 1994, Volume: 131, Issue:2

    Topics: Aged; Aldosterone; Blood Pressure; Humans; Hypertension; Male; Medical Records; Middle Aged; Obesity

1994
Blood pressure responses to dietary salt in rural and urban African men.
    Ethnicity & disease, 1993, Volume: 3 Suppl

    Topics: Adult; Aldosterone; Black People; Developing Countries; Diet, Sodium-Restricted; Humans; Hypertensio

1993
Evidence of abnormalities in corticosteroid secretion leading to volume-dependent hypertension in Milan rats.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:4

    Topics: 18-Hydroxycorticosterone; Adrenal Glands; Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pre

1994
Effects of long-term oral administration of NZ-105, a novel calcium antagonist, with or without propranolol in spontaneously hypertensive rats.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:6

    Topics: Administration, Oral; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel

1993
Escape from the sodium-retaining effects of mineralocorticoids: is there a role for dopamine?
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 78, Issue:2

    Topics: Adenoma; Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Dopamine; Female

1994
Reduced left ventricular distensibility in normotensive men with a positive family history of hypertension.
    American journal of hypertension, 1993, Volume: 6, Issue:9

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Electrocardiography; Heart Rate; Humans; H

1993
[Restructuring of the collagen network in hypertension: role of the angiotensin-aldosterone system].
    Archives des maladies du coeur et des vaisseaux, 1993, Volume: 86, Issue:8

    Topics: Aldosterone; Animals; Collagen; Fibrosis; Humans; Hypertension; Hypertrophy, Left Ventricular; Renin

1993
[Relationship of the renin-angiotensin-aldosterone system with auricular natriuretic factor in its response to the action of thiazide diuretics and to nifedipine, a sustained-release calcium antagonist].
    Medicina clinica, 1994, Jan-22, Volume: 102, Issue:2

    Topics: Aldosterone; Amiloride; Animals; Ants; Blood Pressure; Delayed-Action Preparations; Female; Heart Ra

1994
Treatment with lisinopril normalizes serum concentrations of procollagen type III amino-terminal peptide in patients with essential hypertension.
    American journal of hypertension, 1994, Volume: 7, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Echocardiography; Female; Humans; Hypertension; Lisinopril; Male

1994
[Aldosterone and 11 beta-hydroxysteroid dehydrogenase: role in arterial hypertension].
    La Revue du praticien, 1993, Dec-15, Volume: 43, Issue:20 Suppl

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Humans; Hydroxysteroid Dehydrogenases; Hyperaldo

1993
Association between extracellular volume expansion and urinary calcium excretion in normal humans.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:5

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Volume; Calcium; Extracellular Space; Female; H

1993
Bioelectric impedance analysis of body composition in alcohol-related essential hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:5

    Topics: Adult; Alcoholism; Aldosterone; Body Composition; Body Water; Electric Impedance; Extracellular Spac

1993
How common is primary aldosteronism? Is it the most frequent cause of curable hypertension?
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Australia; Female; Humans; Hyperaldosteronism; Hyperten

1993
Acute sodium loading in patients with uncomplicated diabetes mellitus: renal and hormonal effects.
    Clinical science (London, England : 1979), 1994, Volume: 86, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Diabetes Mellitus; Diabet

1994
Sodium physiopathology and 'nonmodulating' hypertension.
    Contributions to nephrology, 1994, Volume: 106

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Drug Resistance

1994
Hyperkalemia due to hyporeninemic hypoaldosteronism with liver cirrhosis and hypertension.
    Journal of Korean medical science, 1993, Volume: 8, Issue:6

    Topics: Aldosterone; Captopril; Furosemide; Humans; Hyperkalemia; Hypertension; Hypoaldosteronism; Liver Cir

1993
Decreased activity of 11 beta-hydroxysteroid dehydrogenase in mesenteric arteries of Dahl salt-sensitive rats.
    Life sciences, 1994, Volume: 54, Issue:18

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aging; Aldosterone; Animals; Blood Pressure; Body Weight; Cor

1994
Apparent mineralocorticoid excess type II.
    Steroids, 1994, Volume: 59, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Aldosterone; Cortisone; Dexamethasone; Fem

1994
Circulatory and plasma catecholamine responses to mental stress in young subjects with two different types of hypertension.
    Angiology, 1994, Volume: 45, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Diastole; Epinephrine; Humans; Hypertension; Mal

1994
Pathophysiological mechanisms of urbanisation-related hypertension and the sodium pressor response in black Zimbabweans.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1993, Volume: 83, Issue:7

    Topics: Aldosterone; Black People; Blood Pressure; Endothelins; Epoprostenol; Female; Humans; Hypertension;

1993
Cyclosporine-induced stimulation of the renin-angiotensin system after liver and heart transplantation.
    Transplantation, 1993, Volume: 56, Issue:4

    Topics: Aldosterone; Analysis of Variance; Angiotensinogen; Blood Pressure; Cyclosporine; Heart Transplantat

1993
Ambulatory blood pressure changes in the menstrual cycle of hypertensive women. Significance of plasma renin activity values.
    American journal of hypertension, 1993, Volume: 6, Issue:8

    Topics: Adult; Aldosterone; Blood Pressure Determination; Blood Pressure Monitors; Female; Gonadal Steroid H

1993
Plasma levels of brain natriuretic peptide in healthy subjects and patients with essential hypertension: response to posture.
    Clinical science (London, England : 1979), 1993, Volume: 85, Issue:4

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Female; Heart Rate; Humans; Hypertension; Male; Middl

1993
Natriuretic and hypotensive effect of adenosine-1 blockade in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:5

    Topics: Adult; Aldosterone; Blood Pressure; Cyclic AMP; Glomerular Filtration Rate; Heart Rate; Humans; Hype

1993
[Role of aldosterone in essential arterial hypertension complicated by chronic renal insufficiency].
    Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 1993, Volume: 45, Issue:2

    Topics: Adrenocorticotropic Hormone; Aged; Aldosterone; Blood Pressure; Cations; Creatinine; Female; Humans;

1993
11 beta-Hydroxysteroid dehydrogenase activity in mesenteric arteries of spontaneously hypertensive rats.
    Clinical and experimental pharmacology & physiology, 1993, Volume: 20, Issue:10

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Animals; Blood Pressure; Blotting, Northern; Bod

1993
Water immersion and salt-sensitivity in essential hypertension.
    Scandinavian journal of clinical and laboratory investigation, 1993, Volume: 53, Issue:6

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Calcium; Diet; Extracellular Space; F

1993
Nature of elevated blood pressure in normoalbuminuric type I diabetic patients. Essential hypertension?
    American journal of hypertension, 1993, Volume: 6, Issue:10

    Topics: Adolescent; Adult; Albuminuria; Aldosterone; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type

1993
[Unilateral autonomous aldosterone production in hyperaldosteronism suppressible by dexamethasone].
    Deutsche medizinische Wochenschrift (1946), 1993, Dec-17, Volume: 118, Issue:50

    Topics: Adrenal Cortex Hormones; Adult; Aldosterone; Dexamethasone; Female; Humans; Hydrocortisone; Hyperald

1993
Left ventricular hypertrophy in asymptomatic essential hypertension: its relationship with aldosterone and the increase in sodium-proton exchanger activity.
    European heart journal, 1993, Volume: 14 Suppl J

    Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Case-Control Studies; Erythrocytes; Female; Humans;

1993
Renal response to amino acid infusion in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:1 Suppl

    Topics: Adult; Aged; Aldosterone; Amino Acids; Angiotensin II; Blood Pressure; Diastole; Diet, Sodium-Restri

1994
Insulin sensitivity and the effects of insulin on renal sodium handling and pressor systems in essential hypertensive patients.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:1 Suppl

    Topics: Aldosterone; Blood Pressure; Female; Glucose Clamp Technique; Heart Rate; Humans; Hypertension; Infu

1994
The effect of prostaglandin E1 analog misoprostol on chronic cyclosporin nephrotoxicity.
    Journal of pediatric surgery, 1993, Volume: 28, Issue:11

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Chronic Disease; Creatinine; Cyclos

1993
Chronic pressure-natriuresis relationship in dogs with inherited essential hypertension.
    American journal of hypertension, 1993, Volume: 6, Issue:11 Pt 1

    Topics: Aldosterone; Analysis of Variance; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Blood P

1993
The effect of low and high sodium diets on plasma atrial natriuretic factor, the renin-aldosterone system and blood pressure in subjects with essential hypertension.
    Clinical endocrinology, 1994, Volume: 40, Issue:1

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Humans; Hypertension; Male; Middle Aged; Renin; Renin

1994
Regulation of aldosterone secretion in hypertensive blacks.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Black People; Female; Humans; Hyper

1994
Evidence that primary aldosteronism may not be uncommon: 12% incidence among antihypertensive drug trial volunteers.
    Clinical and experimental pharmacology & physiology, 1993, Volume: 20, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hy

1993
Primary aldosteronism: a new understanding.
    The Medical journal of Australia, 1993, Jun-07, Volume: 158, Issue:11

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi

1993
Myocardial fibrosis in the rat with mineralocorticoid excess. Prevention of scarring by amiloride.
    American journal of hypertension, 1993, Volume: 6, Issue:6 Pt 1

    Topics: Aldosterone; Amiloride; Animals; Cardiomyopathies; Cicatrix; Collagen; Disease Models, Animal; Drug

1993
Deficient inactivation of cortisol by 11 beta-hydroxysteroid dehydrogenase in essential hypertension.
    Clinical endocrinology, 1993, Volume: 39, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Carbenoxolone; Cortisone; Female; Humans;

1993
Effects of a calcium antagonist on the pituitary-adrenal axis.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1993, Volume: 25, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure; Calcium Channel Blockers; Female; H

1993
The angiotensin I converting enzyme gene and predisposition to high blood pressure.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 21, Issue:4

    Topics: Adult; Aldosterone; Alleles; Angiotensin II; Blood Pressure; Diastole; Family; Female; Genetic Predi

1993
The role of glucocorticoid activity in the inheritance of hypertension: studies in the rat.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 45, Issue:1-3

    Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Hypertension; Male; Rats; Rats, I

1993
[Effect of different amounts of dietary sodium on plasma atrial natriuretic peptide (ANP)in essential salt sensitive hypertension].
    Polskie Archiwum Medycyny Wewnetrznej, 1993, Volume: 89, Issue:2

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Cyclic GMP; Female; Humans; Hypertension; Male; Renin

1993
[Effect of intravenous sodium chloride load on levels of atrial natriuretic peptide (ANP) and 3'5' guanosine monophosphate (cGMP) in plasma of patients with uncomplicated sodium-sensitive arterial hypertension maintained on different dietary sodium intake
    Polskie Archiwum Medycyny Wewnetrznej, 1993, Volume: 89, Issue:2

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Cyclic GMP; Female; Humans; Hypertension; Infusions,

1993
The relationship between blood pressure and sodium and potassium excretion during the day and at night.
    Journal of hypertension, 1993, Volume: 11, Issue:4

    Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Monitors; Circadian Rhythm; Female; Humans; Hyper

1993
Role of L-arginine-nitric oxide pathway in hypertension.
    Journal of hypertension, 1993, Volume: 11, Issue:6

    Topics: Adult; Aged; Aldosterone; Arginine; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; N

1993
Evaluation of diagnostic tests in the differential diagnosis of primary aldosteronism: unilateral adenoma versus bilateral micronodular hyperplasia.
    The Journal of urology, 1993, Volume: 150, Issue:5 Pt 1

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosteron

1993
Exaggerated natriuresis induced by sodium chloride infusion in essential hypertension is accompanied by an exaggerated urinary 3' 5' guanosine monophosphate excretion.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1993, Volume: 8, Issue:8

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Cyclic GMP; Female; Humans; Hypertension; Infusions,

1993
Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension.
    The American journal of cardiology, 1993, Jan-21, Volume: 71, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Cardiomyopathies; Fibrosis; Hyperaldosteronism; Hypertension;

1993
Influence of arterial blood pressure and aldosterone on left ventricular hypertrophy in moderate essential hypertension.
    The American journal of cardiology, 1993, Jan-21, Volume: 71, Issue:3

    Topics: Adult; Aldosterone; Analysis of Variance; Blood Pressure; Female; Humans; Hypertension; Hypertrophy,

1993
Effects of nitrendipine on blood pressure, renin-angiotensin-system and atrial natriuretic peptide in hypertensive type I diabetic patients.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1993, Volume: 25, Issue:1

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Diabetes Mellitus, Type 1; Diab

1993
Efficacy and mode of action of manidipine: a new calcium antagonist.
    American heart journal, 1993, Volume: 125, Issue:2 Pt 2

    Topics: Adult; Aldosterone; Calcium; Calcium Channel Blockers; Dihydropyridines; Diuresis; Female; Hemodynam

1993
Coronary microvascular fluid flux and permeability: influence of angiotensin II, aldosterone, and acute arterial hypertension.
    The Journal of laboratory and clinical medicine, 1993, Volume: 121, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Capillary Permeability; Coronary Vessels; Dogs; Female; Heart;

1993
Renin-angiotensin-aldosterone system in healthy subjects aged ten to eighteen years.
    The Journal of pediatrics, 1993, Volume: 122, Issue:4

    Topics: Adolescent; Age Factors; Aldosterone; Black People; Child; Female; Humans; Hypertension; Male; Refer

1993
Renin-angiotensin-aldosterone system and arterial hypertension following orthotopic liver transplantation.
    Transplantation proceedings, 1993, Volume: 25, Issue:2

    Topics: Aldosterone; Humans; Hypertension; Liver Transplantation; Prospective Studies; Reference Values; Ren

1993
Antihypertensive action of heparin: role of the renin-angiotensin aldosterone system and prostaglandins.
    Journal of clinical pharmacology, 1993, Volume: 33, Issue:4

    Topics: Aldosterone; Animals; Blood Pressure; Dinoprost; Epoprostenol; Hematocrit; Heparin; Hypertension; In

1993
[Effect of aging on sensitivity of blood pressure to salt].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1993, Volume: 30, Issue:1

    Topics: Adult; Aged; Aging; Aldosterone; Blood Pressure; Epinephrine; Female; Humans; Hypertension; Male; Mi

1993
Sodium retention and hypertension after kidney transplantation in rats.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 21, Issue:5

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Cerebrovascular Disorders; Diet; Hypertension; Ki

1993
Plasma big endothelin-1 concentrations in congestive heart failure patients with or without systemic hypertension.
    The American journal of cardiology, 1993, Jun-01, Volume: 71, Issue:15

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Case-Control Studies; Endothelins; Female; Foll

1993
Atrial natriuretic peptide in non-modulating essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 21, Issue:6 Pt 1

    Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Diet, Sodium-Restricted; Hormones; Hu

1993
Effect of losartan, an angiotensin II receptor antagonist, on response of cortisol and aldosterone to adrenocorticotrophic hormone.
    Journal of clinical pharmacology, 1995, Volume: 35, Issue:8

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Ant

1995
Alterations of calcium metabolism and of parathyroid function in primary aldosteronism, and their reversal by spironolactone or by surgical removal of aldosterone-producing adenomas.
    American journal of hypertension, 1995, Volume: 8, Issue:9

    Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Analysis

1995
Dopamine D5 receptor expression is unchanged in peripheral blood lymphocytes in essential hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1995, Volume: 17, Issue:8

    Topics: Adult; Aldosterone; Benzazepines; Catecholamines; Female; Humans; Hypertension; Lymphocytes; Male; M

1995
Endogenous renal 11 beta-hydroxysteroid dehydrogenase inhibitory factors in patients with low-renin essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Chromatography, High Pressure Liquid; Die

1996
[Mechanism of inhibition of aldosterone secretion by a Ca2+ channel blocker in patients with essential hypertension and patients with primary aldosteronism].
    Nihon Naibunpi Gakkai zasshi, 1995, Nov-20, Volume: 71, Issue:7

    Topics: Adult; Aged; Aldosterone; Calcium Channel Blockers; Depression, Chemical; Female; Humans; Hyperaldos

1995
Converting enzyme inhibition and its withdrawal in spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:3

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinoge

1995
Immunoreactive endogenous ouabain in primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels.
    Journal of hypertension, 1995, Volume: 13, Issue:10

    Topics: Aldosterone; Blood Pressure; Dihydroergotoxine; Dopamine Agonists; Dopamine Antagonists; Female; Hum

1995
Nocturnal blood pressure elevation is related to adrenomedullary hyperactivity, but not to hyperinsulinemia, in nonobese normoalbuminuric type 1 diabetes.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:2

    Topics: Adolescent; Adrenal Medulla; Adult; Albuminuria; Aldosterone; Body Mass Index; Circadian Rhythm; Dia

1996
Chronic ouabain infusion does not cause hypertension in sheep.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood

1996
Prevalence of adrenal and extra-adrenal Conn syndrome in hypertensive patients.
    Archives of internal medicine, 1996, Jun-10, Volume: 156, Issue:11

    Topics: Adrenal Cortex Neoplasms; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism;

1996
Angiotensin converting enzyme gene I/D polymorphism, blood pressure and the renin-angiotensin system in Caucasian and Afro-Caribbean peoples.
    Journal of human hypertension, 1996, Volume: 10, Issue:1

    Topics: Adult; Africa; Aldosterone; Alleles; Black People; Blood Pressure; Caribbean Region; Female; Gene Fr

1996
[Adrenal adenoma or hyperplasia? Problems of differential diagnosis in an unusual case of primary hyperaldosteronism].
    Minerva medica, 1996, Volume: 87, Issue:3

    Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Diagnosis,

1996
[Plasma renin activity, aldosterone and adrenergic activity in patients with hypertension and in normotensives with a family history of hypertension].
    Polskie Archiwum Medycyny Wewnetrznej, 1996, Volume: 95, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Catecholamines; Exercise; Humans; Hypertension; Male; Renin; Stress,

1996
Adrenal tumor producing 11-deoxycorticosterone, 18-hydroxy-11-deoxycorticosterone and aldosterone.
    Internal medicine (Tokyo, Japan), 1996, Volume: 35, Issue:2

    Topics: 18-Hydroxydesoxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Aldosterone; Desoxycorticosterone;

1996
Influence of humoral and neurohormonal factors on cardiovascular hypertrophy in untreated essential hypertensives.
    American journal of hypertension, 1996, Volume: 9, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Blood Pressure Monito

1996
Does industrial environment influence the prevalence of arterial hypertension, plasma cholesterol and uric acid concentration and activity of the renin-aldosterone system?
    Przeglad lekarski, 1996, Volume: 53, Issue:4

    Topics: Adult; Aldosterone; Cholesterol; Environmental Monitoring; Environmental Pollution; Epidemiological

1996
Sodium status, corticosteroid metabolism and blood pressure in normal human subjects and in a patient with abnormal salt appetite.
    Clinical and experimental pharmacology & physiology, 1996, Volume: 23, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Aldosterone; Angiotensin II; Appetite; Female; Humans; Hydroxysteroi

1996
Effects of hyperinsulinaemia on renal function and the pressor system in insulin-resistant obese adolescents.
    Clinical and experimental pharmacology & physiology, 1996, Volume: 23, Issue:4

    Topics: Adolescent; Adrenergic alpha-Agonists; Aldosterone; Glucose Clamp Technique; Humans; Hypertension; I

1996
[Features of endocrine function changes in hypertensive NISAG line rats after exposure to adrenaline].
    Biulleten' eksperimental'noi biologii i meditsiny, 1996, Volume: 121, Issue:5

    Topics: Adrenergic Agonists; Aldosterone; Animals; Corticosterone; Endocrine Glands; Epinephrine; Hypertensi

1996
Physiological significance of plasma sulfoconjugated dopamine in patients with hypertension--clinical and experimental studies.
    Life sciences, 1996, Volume: 59, Issue:4

    Topics: Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure

1996
Modifications induced by -10 degrees Trendelenburg's posture in sodium tubular handling in patients with essential hypertension.
    Blood pressure, 1996, Volume: 5, Issue:1

    Topics: Adult; Aldosterone; Body Mass Index; Dinoprostone; Epinephrine; Female; Head-Down Tilt; Humans; Hype

1996
Aldosterone action, sodium channels and inherited disease.
    The Journal of endocrinology, 1996, Volume: 148, Issue:3

    Topics: Aldosterone; Epithelium; Humans; Hypertension; Hypokalemia; Metabolism, Inborn Errors; Mineralocorti

1996
Effect of central muscarine receptor blockade with DKJ-21 on the blood pressure and heart rate in stress-induced hypertensive rats.
    Blood pressure, 1996, Volume: 5, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Corticosterone; Female; Heart Rate; Hypertension; Male; Muscar

1996
Fluid, ionic and hormonal changes induced by high salt intake in salt-sensitive and salt-resistant hypertensive patients.
    Clinical science (London, England : 1979), 1996, Volume: 91, Issue:2

    Topics: Aldosterone; Atrial Natriuretic Factor; Blood Glucose; Calcium; Cholesterol; Cholesterol, LDL; Creat

1996
Urinary calcium excretion in treated and untreated essential hypertension.
    Journal of the American Society of Nephrology : JASN, 1996, Volume: 7, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Antihypertensive Agents; Benzothiadiazines; Blood G

1996
Renal functional reserve in kidney and heart transplant recipients.
    Journal of the American Society of Nephrology : JASN, 1996, Volume: 7, Issue:8

    Topics: Adult; Aldosterone; Amino Acids; Azathioprine; Creatinine; Cyclosporine; Female; Glomerular Filtrati

1996
Ethnic differences of renin-sodium profile and renal prostaglandins in the pathogenesis of systemic arterial hypertension.
    The Central African journal of medicine, 1996, Volume: 42, Issue:6

    Topics: Adult; Aldosterone; Black People; Case-Control Studies; Dinoprost; Dinoprostone; Female; Humans; Hyp

1996
Primary hyperaldosteronism: a missed diagnosis in 'essential hypertensives'?
    Australian and New Zealand journal of medicine, 1996, Volume: 26, Issue:4

    Topics: Adult; Aldosterone; Biomarkers; Case-Control Studies; Diagnosis, Differential; Female; Humans; Hyper

1996
Fluid homeostasis after heart transplantation: the role of cardiac denervation.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1996, Volume: 15, Issue:9

    Topics: Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Denervation; Electrolytes; Female; Hea

1996
Modulation of target tissue response to angiotensin II and sodium sensitivity in Japanese patients with essential hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1996, Volume: 19, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Infusions, Intrave

1996
Clinical, biochemical and genetic approaches to the detection of familial hyperaldosteronism type I.
    Journal of hypertension, 1995, Volume: 13, Issue:12 Pt 2

    Topics: Adolescent; Adult; Aged; Aldosterone; Base Sequence; Blood Pressure; Blotting, Southern; Child; DNA;

1995
Albuminuria in untreated patients with primary aldosteronism or essential hypertension.
    Journal of hypertension, 1995, Volume: 13, Issue:12 Pt 2

    Topics: Albuminuria; Aldosterone; beta 2-Microglobulin; Female; Humans; Hyperaldosteronism; Hypertension; Ma

1995
Chronic carvedilol reduces mortality and renal damage in hypertensive stroke-prone rats.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2

    Topics: Adrenergic beta-Antagonists; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Body Wei

1996
Alpha-fluoromethylhistidine, an inhibitor of histamine biosynthesis, causes arterial hypertension.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 354, Issue:5

    Topics: Aldosterone; Analysis of Variance; Animals; Behavior, Animal; Blood Pressure; Catecholamines; Heart

1996
[Aldosterone precursors and hypertension with hypokalemia and adrenal module non caused by primary hyperaldosteronism].
    Archives des maladies du coeur et des vaisseaux, 1996, Volume: 89, Issue:8

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Diagnosis, Differential; Female; Humans;

1996
The role of intermediate phenotypes in essential hypertension: non-modulation as a model.
    Endocrine research, 1996, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Blood Flow Velocity; Genotype

1996
The resistance of the Wistar/Furth rat strain to steroid hypertension.
    Endocrine research, 1996, Volume: 22, Issue:4

    Topics: Adenosine Triphosphatases; Aldosterone; Animals; Desoxycorticosterone; Dexamethasone; Gene Expressio

1996
11 beta-Hydroxylase activity in glucocorticoid suppressible hyperaldosteronism: lessons for essential hypertension?
    Endocrine research, 1996, Volume: 22, Issue:4

    Topics: Adrenocorticotropic Hormone; Aldosterone; Chimera; Corticosterone; Cortodoxone; Cytochrome P-450 CYP

1996
Regulation of 11 beta-hydroxylase cytochrome p450 expression by cholesterol in spontaneously hypertensive rats.
    Journal of hypertension, 1995, Volume: 13, Issue:11

    Topics: Adrenal Cortex; Aldosterone; Animals; Cholesterol, Dietary; Cohort Studies; Corticosterone; Cytochro

1995
Effect of chronic ethanol consumption on the atrial natriuretic system of spontaneously hypertensive rats.
    Alcoholism, clinical and experimental research, 1996, Volume: 20, Issue:9

    Topics: Aging; Alcohol Drinking; Aldosterone; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Bloo

1996
Effects of estrogen replacement therapy on the renin-angiotensin system in postmenopausal women.
    Circulation, 1997, Jan-07, Volume: 95, Issue:1

    Topics: Aged; Aldosterone; Analysis of Variance; Angiotensinogen; Estradiol; Estriol; Estrogen Replacement T

1997
Effects of nifedipine treatment on the renin-angiotensin-aldosterone axis.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:2

    Topics: Aged; Aldosterone; Blood Pressure; Delayed-Action Preparations; Female; Humans; Hypertension; Male;

1997
Structure and function of steroid dehydrogenases involved in hypertension, fertility, and cancer.
    Steroids, 1997, Volume: 62, Issue:1

    Topics: Aldosterone; Amino Acid Sequence; Binding Sites; Conserved Sequence; Cortisone Reductase; Crystallog

1997
Liddle's syndrome: a 14-year follow-up of the youngest diagnosed case.
    Pediatric nephrology (Berlin, Germany), 1997, Volume: 11, Issue:1

    Topics: Aldosterone; Alkalosis; Blood Pressure; Child; Female; Follow-Up Studies; Growth; Humans; Hypertensi

1997
Associations between circulating components of the renin-angiotensin-aldosterone system and left ventricular mass.
    Heart (British Cardiac Society), 1997, Volume: 77, Issue:1

    Topics: Age Factors; Aged; Aldosterone; Blood Pressure; Body Mass Index; Echocardiography; Female; Humans; H

1997
Vascular aldosterone in genetically hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:1 Pt 1

    Topics: Aldosterone; Animals; Blotting, Northern; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP

1997
Increased Na(+)-H+ exchange in red blood cells of patients with primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Age Factors; Aldosterone; Blood Pressure; Calmodulin; Erythrocytes;

1997
An abnormal sodium metabolism in Japanese patients with essential hypertension, judged by serum sodium distribution, renal function and the renin-aldosterone system.
    Journal of hypertension, 1997, Volume: 15, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Ki

1997
Left ventricular hypertrophy precedes other target-organ damage in primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:3

    Topics: Adult; Aged; Aldosterone; Electrocardiography; Female; Humans; Hyperaldosteronism; Hypertension; Hyp

1997
[Hypertensive subpopulations as defined by their natriuretic response to ambulation].
    Medicina clinica, 1997, Jan-18, Volume: 108, Issue:2

    Topics: Adult; Aged; Aldosterone; Catecholamines; Dinoprostone; Female; Humans; Hypertension; Kallikreins; M

1997
Development of polyuria in Tsukuba hypertensive mice carrying human renin and angiotensinogen genes.
    Clinical and experimental pharmacology & physiology. Supplement, 1995, Volume: 22, Issue:1

    Topics: Aldosterone; Angiotensinogen; Animals; Electrolytes; Humans; Hyperaldosteronism; Hypertension; Kidne

1995
Urinary excretion of 19-noraldosterone in the spontaneously hypertensive rat and stroke-prone spontaneously hypertensive rat.
    Clinical and experimental pharmacology & physiology. Supplement, 1995, Volume: 22, Issue:1

    Topics: Aldosterone; Animals; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Hypertension;

1995
Renin-angiotensin system in the antihypertensive effect of isoteoline in spontaneously hypertensive rats.
    Clinical and experimental pharmacology & physiology. Supplement, 1995, Volume: 22, Issue:1

    Topics: Aldosterone; Animals; Antihypertensive Agents; Aporphines; Blood Pressure; Hypertension; In Vitro Te

1995
Resistance to mineralocorticoids in Wistar-Furth rats.
    The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 2

    Topics: Aldosterone; Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Cells, Cultured; Citrate (

1997
Age, gender, and non-modulation. A sexual dimorphism in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Data Interpretat

1997
Liddle's syndrome: prospective genetic screening and suppressed aldosterone secretion in an extended kindred.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Female; Frameshift Mutation; Genetic Testing;

1997
Serum gamma-glutamyl transferase levels and blood pressure falls after alcohol moderation.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1997, Volume: 19, Issue:3

    Topics: Adult; Aged; Alcohol Drinking; Aldosterone; Blood Platelets; Blood Pressure; Calcium; Catecholamines

1997
Remodeling of the left ventricle in primary aldosteronism due to Conn's adenoma.
    Circulation, 1997, Mar-18, Volume: 95, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Blood Flow Velocity; Coronary Circulatio

1997
Genetic analysis of renin gene expression in the central nervous system of spontaneously hypertensive rats.
    Neuroscience letters, 1997, Jan-17, Volume: 221, Issue:2-3

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Brain Stem; Central Nervous System; DNA; Female;

1997
Hypertensive cardiomegaly caused by an aldosterone-secreting adenoma in a newborn.
    Journal of endocrinological investigation, 1997, Volume: 20, Issue:2

    Topics: Adenoma; Adrenalectomy; Aldosterone; Cardiomegaly; Humans; Hyperaldosteronism; Hypertension; Infant;

1997
[The morphofunctional characteristics of the zona glomerulosa of the adrenal cortex in rats with hereditary stress-induced arterial hypertension].
    Morfologiia (Saint Petersburg, Russia), 1996, Volume: 110, Issue:6

    Topics: Aldosterone; Animals; Hypertension; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Rats, Wi

1996
Effects of moxibustion on blood pressure and renal function in spontaneously hypertensive rats.
    The American journal of Chinese medicine, 1997, Volume: 25, Issue:1

    Topics: Acupuncture Points; Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Chlorides; Crea

1997
Impact of the renin-angiotensin-aldosterone system on blood pressure response to intravenous enalaprilat in patients with hypertensive crises.
    Journal of human hypertension, 1997, Volume: 11, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Emergencies; Enalaprilat; Female; Human

1997
Lack of evidence for the interaction between renin-angiotensin-aldosterone system and endothelin in vivo.
    Physiological research, 1996, Volume: 45, Issue:3

    Topics: Adult; Aldosterone; Antihypertensive Agents; Captopril; Endothelins; Endothelium; Humans; Hypertensi

1996
Pharmacological profile of valsartan, a non-peptide angiotensin II type 1 receptor antagonist. 1st communication: antihypertensive effects of valsartan in hypertensive models.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:5

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertens

1997
Left ventricular hypertrophy is more prominent in patients with primary aldosteronism than in patients with other types of secondary hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1997, Volume: 20, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Cushing Syndrome; Echocardiography; Female; Humans; Hyp

1997
Influence of different dietary salts on the cardiovascular and renal effects of moxonidine in spontaneously hypertensive rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:1

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Drinking;

1997
Role of the renal kallikrein-kinin system in the development of hypertension.
    Immunopharmacology, 1997, Volume: 36, Issue:2-3

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Bradykini

1997
Plasma renin activity in heart failure-prone SHHF/Mcc-facp rats.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2

    Topics: Aging; Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Blood Volume; Disease Suscep

1997
Mechanisms in the pressor effects of hepatic portal venous fatty acid infusion.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2

    Topics: Acetylcholine; Aldosterone; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pre

1997
Relationship between some humoral factors and left ventricular hypertrophy in essential hypertension.
    Chinese medical journal, 1996, Volume: 109, Issue:11

    Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Midd

1996
Autonomy of the renin system in type II diabetes mellitus: dietary sodium and renal hemodynamic responses to ACE inhibition.
    Kidney international, 1997, Volume: 52, Issue:3

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitu

1997
Sodium chloride and hypertension.
    Medical hypotheses, 1997, Volume: 49, Issue:3

    Topics: Aldosterone; Arteriosclerosis; China; Diet; Extracellular Space; Humans; Hypertension; Hypotonic Sol

1997
Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion.
    Cardiovascular research, 1997, Volume: 35, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Aorta; Autoradiography; Binding Sites; Endomyocardial Fibrosis

1997
The role of blood pressure and aldosterone in the production of hemorrhagic stroke in captopril-treated hypertensive rats.
    Stroke, 1997, Volume: 28, Issue:9

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cerebral

1997
[Electrolyte metabolism and endocrine indices in the plasma and lymph of rats with hereditary arterial hypertension].
    Biulleten' eksperimental'noi biologii i meditsiny, 1997, Volume: 124, Issue:7

    Topics: Aldosterone; Animals; Electrolytes; Hypertension; Insulin; Lymph; Male; Potassium; Rats; Rats, Wista

1997
Effects of the glucocorticoid II receptor antagonist mifepristone on hypertension in the obese Zucker rat.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Corticosterone; Hypertension; Male; Mifepristone; Obesity; Rat

1997
Brain nitric oxide synthase messenger RNA in central mineralocorticoid hypertension.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:4

    Topics: Aldosterone; Animals; Brain; Hypertension; Injections, Intraventricular; Mineralocorticoids; Nitric

1997
Long-term blockade of the angiotensin II receptor in renin transgenic rats, salt-loaded Dahl rats, and stroke-prone spontaneously hypertensive rats.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:9

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modifie

1997
Evaluation of the dexamethasone suppression test for the diagnosis of glucocorticoid-remediable aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:11

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Cytochrome P-450 CYP11B2; Dexamethasone; Glucocorti

1997
Role of renin-angiotensin-aldosterone system and of sympathetic activity in arterial hypertension associated with autosomal dominant polycystic kidney disease.
    Contributions to nephrology, 1997, Volume: 122

    Topics: Aldosterone; Blood Pressure; Catecholamines; Female; Humans; Hypertension; Hypertension, Renal; Male

1997
Dopamine D3 receptor in peripheral mononuclear cells of essential hypertensives.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:6

    Topics: Adult; Aldosterone; Binding, Competitive; Blood Pressure; Dopamine; Epinephrine; Female; Humans; Hyp

1997
[A case of apparent mineralocorticoid excess caused by type 2 11 beta- hydroxysteroid dehydrogenase deficiency].
    Archives des maladies du coeur et des vaisseaux, 1997, Volume: 90, Issue:8

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Child, Preschool; Cortisone; Female; Humans; Hyd

1997
[Cardio-protection and cardio-reparation in systemic arterial hypertension].
    Revista espanola de cardiologia, 1997, Volume: 50 Suppl 4

    Topics: Aldosterone; Antihypertensive Agents; Electrocardiography; Humans; Hypertension; Hypertrophy, Left V

1997
Coexisting renal artery stenosis and primary aldosteronism.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:12

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi

1997
[Association between blood pressure and circulating hormonal factors with left ventricular mass in patients with essential hypertension older than 55 years of age].
    Medicina clinica, 1997, Oct-11, Volume: 109, Issue:12

    Topics: Aged; Aldosterone; Cardiomegaly; Endothelin-1; Epinephrine; Female; Humans; Hypertension; Male; Midd

1997
Association between increased plasma levels of aldosterone and decreased systemic arterial compliance in subjects with essential hypertension.
    American journal of hypertension, 1997, Volume: 10, Issue:12 Pt 1

    Topics: Adult; Aged; Aldosterone; Arteries; Compliance; Diltiazem; Hemodynamics; Humans; Hypertension; Male;

1997
Endothelial dysfunction in hypertension is independent from the etiology and from vascular structure.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2

    Topics: Acetylcholine; Adipose Tissue; Adrenal Gland Neoplasms; Aldosterone; Arterioles; Blood Pressure; Cho

1998
Neurohormonal activity and left ventricular geometry in patients with essential arterial hypertension.
    American heart journal, 1998, Volume: 135, Issue:1

    Topics: Aldosterone; Atrial Natriuretic Factor; Case-Control Studies; Echocardiography, Doppler; Female; Hea

1998
Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo.
    The American journal of physiology, 1998, Volume: 274, Issue:1

    Topics: Actins; Aldosterone; Animals; Aorta, Thoracic; Carbachol; Cardiomegaly; Cell Cycle; DNA; Heart; Hype

1998
[Alterations of calcium, magnesium, and zinc in essential hypertension:their relation to the renin-angiotensin-aldosterone system].
    Investigacion clinica, 1997, Volume: 38 Suppl 2

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Black People; Calcium;

1997
Plasma atrial natriuretic peptide and natriuretic peptide receptor gene expression in adipose tissue of normotensive and hypertensive obese patients.
    Journal of hypertension, 1997, Volume: 15, Issue:12 Pt 2

    Topics: Actins; Adipose Tissue; Aldosterone; Atrial Natriuretic Factor; Biopsy, Needle; DNA Primers; Female;

1997
Evidence for persistent dysfunction of wild-type aldosterone synthase gene in glucocorticoid-treated familial hyperaldosteronism type I.
    Journal of hypertension, 1997, Volume: 15, Issue:12 Pt 2

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Blotting, Southern; Cytochrome P-450 CYP11B2;

1997
Circadian blood pressure variation in hypertensive patients with primary hyperaldosteronism.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:3

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; F

1998
Renal functional reserve in IDDM patients.
    Diabetologia, 1998, Volume: 41, Issue:1

    Topics: Adult; Albuminuria; Aldosterone; Amino Acids; Blood Glucose; Blood Pressure; C-Peptide; Creatinine;

1998
[Renin-aldosterone system in secretion of cortisol in patients with arterial hypertension in European North].
    Klinicheskaia meditsina, 1998, Volume: 76, Issue:1

    Topics: Adult; Aldosterone; Arctic Regions; Blood Pressure; Environmental Exposure; Humans; Hydrocortisone;

1998
Opposite associations of circulating aldosterone and atrial natriuretic peptide with left ventricular diastolic function in essential hypertension.
    Journal of human hypertension, 1998, Volume: 12, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Coronary Circulation; Diastole; Echoc

1998
[Hypertension treatable with glucocorticoids: report of a case].
    Revista medica de Chile, 1997, Volume: 125, Issue:11

    Topics: Aldosterone; Dexamethasone; Female; Glucocorticoids; Humans; Hypertension; Middle Aged; Potassium; S

1997
[Mutation T-->C of nucleotide 2238 in the gene of atrial natriuretic peptide (ANP) precursor and heterogeneity of sodium-sensitive hypertension. Preliminary report].
    Polskie Archiwum Medycyny Wewnetrznej, 1997, Volume: 98, Issue:12

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Base Sequence; DNA; Female; Genotype; Humans; Hyperte

1997
The diagnosis of Liddle syndrome by identification of a mutation in the beta subunit of the epithelial sodium channel.
    Journal of medical genetics, 1998, Volume: 35, Issue:6

    Topics: Aldosterone; Alleles; Amino Acid Sequence; Base Sequence; Blood Pressure; Chromosome Mapping; Chromo

1998
[Case of primary aldosteronism associated with heart and kidney failure].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1998, May-10, Volume: 87, Issue:5

    Topics: Aldosterone; Biomarkers; Female; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Kidney Dis

1998
Effects of dietary gamma-linolenic acid on blood pressure and adrenal angiotensin receptors in hypertensive rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1998, Volume: 218, Issue:3

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone; Dietary Fats,

1998
T235 variant of the angiotensinogen gene and blood pressure in the Chilean population.
    Journal of hypertension, 1998, Volume: 16, Issue:6

    Topics: Aldosterone; Angiotensinogen; Blood Pressure; Chile; DNA; DNA Primers; Female; Genotype; Humans; Hyp

1998
Decreased blood pressure variability at rest in patients with primary aldosteronism.
    American journal of hypertension, 1998, Volume: 11, Issue:7

    Topics: Adult; Aldosterone; Baroreflex; Blood Pressure; Diastole; Exercise; Female; Heart Rate; Humans; Hype

1998
Genetic determination of plasma aldosterone levels in essential hypertension.
    American journal of hypertension, 1998, Volume: 11, Issue:7

    Topics: Age Factors; Aldosterone; Biomarkers; Blood Flow Velocity; Blood Pressure; Body Height; Body Weight;

1998
Molecular basis for hypertension in the "type II variant" of apparent mineralocorticoid excess.
    American journal of human genetics, 1998, Volume: 63, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Amino Acid Substitution; Base Sequence; B

1998
Aldosterone overproduction and CYP11B2 mRNA overexpression in vessels of spontaneously hypertensive rats.
    Hormone research, 1998, Volume: 50, Issue:1

    Topics: Aldosterone; Animals; Aorta; Arteries; Cytochrome P-450 CYP11B2; Gene Expression; Hypertension; Mese

1998
Associations between aldosterone synthase gene polymorphism and the adrenocortical function in males.
    Journal of internal medicine, 1998, Volume: 244, Issue:1

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Analysis of Variance; Cohort Studie

1998
Insulin resistance in essential hypertension is related to plasma renin activity.
    Journal of human hypertension, 1998, Volume: 12, Issue:6

    Topics: Aged; Aldosterone; Blood Pressure; Female; Glucose Clamp Technique; Glucose Tolerance Test; Humans;

1998
Modifications of myocardial Na+,K(+)-ATPase isoforms and Na+/Ca2+ exchanger in aldosterone/salt-induced hypertension in guinea pigs.
    Cardiovascular research, 1998, Volume: 38, Issue:2

    Topics: Aldosterone; Animals; Blotting, Northern; Blotting, Western; Echocardiography; Guinea Pigs; Hyperten

1998
Aldosterone stimulates Na,K-ATPase activity in basolateral membrane of rat kidney.
    Biochemistry and molecular biology international, 1998, Volume: 45, Issue:5

    Topics: Aldosterone; Animals; Binding Sites; Dactinomycin; Gene Expression Regulation, Enzymologic; Hyperten

1998
Association between a polymorphism in the G protein beta3 subunit gene and lower renin and elevated diastolic blood pressure levels.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:3

    Topics: Aged; Aldosterone; Analysis of Variance; Anthropometry; Antihypertensive Agents; Blood Pressure; Coh

1998
Differential catecholamine responses to protein intake in healthy and hypertensive subjects.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Dietary Prot

1998
Vascular and neuroendocrine components in altered blood pressure regulation after surgical repair of coarctation of the aorta.
    Journal of human hypertension, 1998, Volume: 12, Issue:8

    Topics: Adolescent; Adult; Aldosterone; Aortic Coarctation; Blood Flow Velocity; Blood Pressure; Child; Chil

1998
Mutations in the carboxy terminus of the beta and gamma subunits of the epithelial sodium channel are not present in patients with hypertensive crisis.
    European journal of clinical investigation, 1998, Volume: 28, Issue:9

    Topics: Adult; Aged; Aldosterone; Amino Acid Sequence; Base Sequence; DNA; Emergencies; Female; Humans; Hype

1998
Differential glucose tolerance in dipper and nondipper essential hypertension: the implications of circadian blood pressure regulation on glucose tolerance in hypertension.
    Diabetes care, 1998, Volume: 21, Issue:10

    Topics: Adult; Aldosterone; Autonomic Nervous System; Blood Glucose; Blood Pressure; Catecholamines; Cholest

1998
Hormonal characteristics of primary aldosteronism due to unilateral adrenal hyperplasia.
    Journal of endocrinological investigation, 1998, Volume: 21, Issue:8

    Topics: Adrenal Cortex; Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldosteron

1998
Structure-function relationships of aldosterone synthase and 11 beta-hydroxylase enzymes: implications for human hypertension.
    Clinical and experimental pharmacology & physiology. Supplement, 1998, Volume: 25

    Topics: 18-Hydroxycorticosterone; Aldosterone; Animals; COS Cells; Cytochrome P-450 CYP11B2; Humans; Hyperte

1998
Aldosterone: a hormone with adverse autonomic effects?
    Clinical science (London, England : 1979), 1998, Volume: 95, Issue:6

    Topics: Aldosterone; Animals; Autonomic Nervous System; Baroreflex; Cardiovascular System; Homeostasis; Huma

1998
Renal effects of leptin in normotensive, hypertensive, and obese rats.
    The American journal of physiology, 1998, Volume: 275, Issue:6

    Topics: Aldosterone; Animals; Blood Pressure; Hemodynamics; Hypertension; Kidney; Leptin; Male; Obesity; Pro

1998
Pressure-natriuresis and -diuresis in transgenic rats harboring both human renin and human angiotensinogen genes.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:12

    Topics: Aldosterone; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Diuresis; Huma

1998
Hormonal response to orthostasis in elderly people with systemic systolic hypertension.
    Coronary artery disease, 1998, Volume: 9, Issue:9

    Topics: Aged; Aldosterone; Atrial Natriuretic Factor; Cardiac Output; Hemodynamics; Humans; Hypertension; Ma

1998
In vivo left ventricular function and collagen expression in aldosterone/salt-induced hypertension.
    Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:6

    Topics: Aldosterone; Animals; Collagen; Electrolytes; Fibrosis; Guinea Pigs; Hormones; Hypertension; Hypertr

1998
Possible mechanisms of salt-induced hypertension in Dahl salt-sensitive rats.
    Physiology & behavior, 1998, Dec-01, Volume: 65, Issue:3

    Topics: Aldosterone; Animals; Aorta; Arginine Vasopressin; Blood Pressure; Body Weight; Cyclic GMP; Diet, So

1998
Adrenal tumors and pregnancy.
    World journal of surgery, 1999, Volume: 23, Issue:2

    Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Fatal Outc

1999
Left ventricular systolic function in primary aldosteronism and hypertension.
    Journal of hypertension, 1998, Volume: 16, Issue:12 Pt 2

    Topics: Adult; Aldosterone; Echocardiography, Doppler; Female; Humans; Hyperaldosteronism; Hypertension; Hyp

1998
Circadian variation of urinary microalbumin excretion and ambulatory blood pressure in patients with essential hypertension.
    Journal of hypertension, 1998, Volume: 16, Issue:12 Pt 2

    Topics: Adult; Aged; Albuminuria; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Blood Pressure Mon

1998
Impaired baroreflex function and arterial compliance in primary aldosteronism.
    Journal of human hypertension, 1999, Volume: 13, Issue:1

    Topics: Adult; Aldosterone; Arteries; Baroreflex; Blood Pressure; Compliance; Female; Heart Rate; Hemodynami

1999
High and non-suppressible plasma renin activity in a patient with aldosterone producing adenoma: pathophysiologic and diagnostic implications.
    Journal of human hypertension, 1999, Volume: 13, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Hypertension; Renin

1999
Renal characteristics and effect of angiotensin suppression in oral contraceptive users.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressur

1999
Genetic polymorphism of CYP11B2 gene and hypertension in Japanese.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1 Pt 2

    Topics: Adult; Aged; Aldosterone; Amino Acid Substitution; Blood Pressure; Cytochrome P-450 CYP11B2; DNA; Fe

1999
Potentially high prevalence of primary aldosteronism in a primary-care population.
    Lancet (London, England), 1999, Jan-02, Volume: 353, Issue:9146

    Topics: Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Predictive Value of Tests

1999
Low calorie diet enhances renal, hemodynamic, and humoral effects of exogenous atrial natriuretic peptide in obese hypertensives.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:2

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Diet; Diuresis; Female; Hemodynamics; Humans; Hyper

1999
Aldosterone excretion rate and blood pressure in essential hypertension are related to polymorphic differences in the aldosterone synthase gene CYP11B2.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:2

    Topics: Adult; Aldosterone; Alleles; Blood Pressure; Cytochrome P-450 CYP11B2; Female; Genetic Linkage; Huma

1999
Effects of the new angiotensin II type 1 receptor antagonist KRH-594 on several types of experimental hypertension.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:1

    Topics: Administration, Oral; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists;

1999
Adrenal cancer with hypertension but low plasma renin and aldosterone.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1999, Volume: 98, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adult; Aldosterone; Carcinoma; Female; Humans; Hypertension; Renin

1999
[Relations between blood insulin concentration, renin-angiotensin-aldosterone system and clinical picture of hypertension].
    Terapevticheskii arkhiv, 1999, Volume: 71, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Biomarkers; Blood Glucose; Blood Pressure; Echocardiography; Glu

1999
Clinic-daytime blood pressure difference and cardiovascular damage.
    Journal of hypertension, 1999, Volume: 17, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carotid Arteries; Cholest

1999
Hyponatremic-hypertensive syndrome with renal ischemia: an underrecognized disorder.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Female; Humans; Hypertension; Hyponatremia; Male; Middl

1999
Epithelial sodium channel activity is not increased in hypertension in whites.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:4

    Topics: Adult; Aldosterone; Amiloride; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans;

1999
Aldosterone directly induces Na, K-ATPase alpha 1-subunit mRNA in the renal cortex of rat.
    Biochemistry and molecular biology international, 1999, Volume: 47, Issue:2

    Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Gene Expression Regulation, Enzymologic; Hypertensi

1999
[Levels of biologically active substances in the blood of patients resistant and nonresistant to antihypertensive therapy].
    Terapevticheskii arkhiv, 1999, Volume: 71, Issue:3

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Drug Resistance;

1999
Docosahexaenoic acid is an antihypertensive nutrient that affects aldosterone production in SHR.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1999, Volume: 221, Issue:1

    Topics: Adrenal Glands; Aldosterone; Animals; Antihypertensive Agents; Arachidonic Acid; Blood Pressure; Cor

1999
Beta-adrenergic receptor blockade as a therapeutic approach for suppressing the renin-angiotensin-aldosterone system in normotensive and hypertensive subjects.
    American journal of hypertension, 1999, Volume: 12, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme

1999
Beta-adrenergic receptor blockade as a therapeutic approach for suppressing the renin-angiotensin-aldosterone system in normotensive and hypertensive subjects.
    American journal of hypertension, 1999, Volume: 12, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme

1999
Beta-adrenergic receptor blockade as a therapeutic approach for suppressing the renin-angiotensin-aldosterone system in normotensive and hypertensive subjects.
    American journal of hypertension, 1999, Volume: 12, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme

1999
Beta-adrenergic receptor blockade as a therapeutic approach for suppressing the renin-angiotensin-aldosterone system in normotensive and hypertensive subjects.
    American journal of hypertension, 1999, Volume: 12, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme

1999
Adrenocortical activity in the newborn spontaneously hypertensive rat.
    American journal of hypertension, 1999, Volume: 12, Issue:5

    Topics: Adrenal Cortex; Aldosterone; Animals; Animals, Newborn; Biomarkers; Blood Pressure; Corticosterone;

1999
Maternal hypertension and progeny blood pressure: role of aldosterone and 11beta-HSD.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Animals; Blood Pressure; Cerebral Ventric

1999
Effects of cholic acid on blood pressure and production of vascular aldosterone and corticosterone.
    Steroids, 1999, Volume: 64, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aged; Aldosterone; Animals; Bile Acids and Salts; Bloo

1999
Significance of sympathetic nervous system in sodium-induced nocturnal hypertension.
    Journal of hypertension, 1999, Volume: 17, Issue:7

    Topics: Aldosterone; Circadian Rhythm; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle A

1999
Medical management of aldosterone-producing adenomas.
    Annals of internal medicine, 1999, Jul-20, Volume: 131, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure;

1999
[Woman with refractory hypertension and hypokalemia].
    Revista clinica espanola, 1999, Volume: 199, Issue:6

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Adrenocorticotrop

1999
[Mineralocorticoid hypertension. A new form of secondary hypertension?].
    Revista medica de Chile, 1999, Volume: 127, Issue:5

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoids; Renin; Renin-Angiotensin

1999
Hyper-responsiveness to angiotensin II is related to cardiac structural adaptation in hypertensive subjects.
    Journal of hypertension, 1999, Volume: 17, Issue:6

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Hype

1999
Primary aldosteronism in general practice.
    Lancet (London, England), 1999, Mar-20, Volume: 353, Issue:9157

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; False Positive React

1999
Aldosterone-producing adenoma without hypertension: a report of two cases.
    European journal of endocrinology, 1999, Volume: 141, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure Moni

1999
Vascular remodeling in hypertensive transgenic mice.
    Experimental animals, 1999, Volume: 48, Issue:3

    Topics: Aldosterone; Animals; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Blood Pressure; Disease M

1999
Low-renin and nonmodulating essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:3

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Renin; Sodium Channels; Vasoconstrictor Agents

1999
Approach to a patient with suspected primary aldosteronism.
    Singapore medical journal, 1999, Volume: 40, Issue:5

    Topics: Aldosterone; Diagnosis, Differential; Female; Hematologic Tests; Humans; Hyperaldosteronism; Hyperte

1999
Altered sodium perception in essential hypertensive patients following rapid volume expansion.
    Journal of human hypertension, 1999, Volume: 13, Issue:10

    Topics: Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Dextrans; Female;

1999
Genetic variants in the epithelial sodium channel in relation to aldosterone and potassium excretion and risk for hypertension.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:4 Pt 1

    Topics: Adolescent; Aldosterone; Black People; Blood Pressure; Cohort Studies; Epithelial Cells; Exons; Fema

1999
A(-6)G variant of angiotensinogen gene and aldosterone levels in hypertensives.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:4 Pt 2

    Topics: Aged; Aldosterone; Angiotensinogen; Female; Gene Frequency; Humans; Hypertension; Male; Middle Aged;

1999
Effect of poststroke captopril treatment on mortality associated with hemorrhagic stroke in stroke-prone rats.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Aldosterone; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Captopril;

1999
Relation between the renin-angiotensin-aldosterone system and left ventricular structure and function in young normotensive and mildly hypertensive subjects.
    American heart journal, 1999, Volume: 138, Issue:5 Pt 1

    Topics: Adult; Aldosterone; Angiotensin II; Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring,

1999
[Left ventricular myocardial structure and function in patients with primary aldosteronism].
    Terapevticheskii arkhiv, 1999, Volume: 71, Issue:9

    Topics: Adrenalectomy; Adult; Aldosterone; Blood Flow Velocity; Blood Pressure; Echocardiography, Doppler; F

1999
Biochemical evidence of aldosterone overproduction and abnormal regulation in normotensive individuals with familial hyperaldosteronism type I.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:11

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Child; Dexamethasone; Female; Glucocorticoids; Homeo

1999
[Hypertension plus hypokalemia should direct the line of thoughts toward Liddle's syndrome].
    Lakartidningen, 1999, Oct-27, Volume: 96, Issue:43

    Topics: Adult; Aldosterone; Cataract; Diagnosis, Differential; Female; Humans; Hypertension; Hypokalemia; Im

1999
[Mineralocorticoid-like hypertension. "Apparent mineralocorticoid excess". A hereditary type of hypertension?].
    Ugeskrift for laeger, 1999, Oct-18, Volume: 161, Issue:42

    Topics: Adolescent; Adult; Aldosterone; Amiloride; Chromosome Aberrations; Chromosome Disorders; Diuretics;

1999
A case of neurofibromatosis type 1 with an aldosterone-producing adenoma of the adrenal.
    Journal of internal medicine, 1999, Volume: 246, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Causality; Female; Humans; Hypertension; Neuro

1999
Prevalence of mild apparent mineralocorticoid excess in Mennonites.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:12

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Child; Christianity; Consanguinity; Female; Gene

1999
Different platelet aggregability during mental stress in two stages of essential hypertension.
    American journal of hypertension, 1999, Volume: 12, Issue:11 Pt 1

    Topics: Adenosine Diphosphate; Adult; Aged; Aldosterone; beta-Thromboglobulin; Binding Sites; Biomarkers; Bl

1999
Relation between dehydroepiandrosterone sulfate and blood pressure levels in a population-based sample.
    American journal of hypertension, 1999, Volume: 12, Issue:11 Pt 1

    Topics: Aged; Aldosterone; Androstenedione; Biomarkers; Blood Pressure; Dehydroepiandrosterone Sulfate; Fema

1999
Platelet magnesium depletion in normotensive and hypertensive obese subjects: the role of salt-regulating hormones and catecholamines.
    Magnesium research, 1999, Volume: 12, Issue:4

    Topics: Adult; Aldosterone; Blood Platelets; Epinephrine; Female; Humans; Hypertension; Magnesium; Magnesium

1999
Adrenocortical activity in fetal SHR and WKY rats.
    Pediatric research, 2000, Volume: 47, Issue:1

    Topics: Adrenal Cortex; Aldosterone; Animals; Corticosterone; Cytochrome P-450 Enzyme System; Female; Fetus;

2000
Autonomic abnormalities demonstrable in young normotensive subjects who are children of hypertensive parents.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2000, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Baroreflex; Blood Pressure; Body Mass Index; Chi-Square Distribution

2000
[Animal experiment models of hypertension in pregnancy--an alternative to clinical studies?].
    Zentralblatt fur Gynakologie, 1999, Volume: 121, Issue:12

    Topics: Aldosterone; Animals; Disease Models, Animal; Female; Hematocrit; Humans; Hypertension; Infant, Newb

1999
[High prevalence of undiagnosed primary hyperaldosteronism among patients with essential hypertension].
    Revista medica de Chile, 1999, Volume: 127, Issue:7

    Topics: Aldosterone; Comorbidity; Female; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Middl

1999
Salt-induced exacerbation of morning surge in blood pressure in patients with essential hypertension.
    Journal of human hypertension, 2000, Volume: 14, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Aldosterone; Baroreflex; Blood Pressure; Blood Pressure

2000
Controlled study of circadian rhythm of blood pressure in patients with aldosterone-producing adenoma compared with those with essential hypertension.
    Journal of hypertension, 2000, Volume: 18, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Blood Pressure; Blood Pressure

2000
[Features of dopaminergic system function in menopausal females with arterial hypertension].
    Terapevticheskii arkhiv, 2000, Volume: 72, Issue:1

    Topics: Adult; Aldosterone; Antihypertensive Agents; Biomarkers; Blood Pressure; Bromocriptine; Dopamine; Do

2000
Comment on "Interactions between endothelin-1 and the renin-angiotensin-aldosterone system".
    Cardiovascular research, 1999, Volume: 44, Issue:2

    Topics: Aldosterone; Animals; Animals, Genetically Modified; Endothelin Receptor Antagonists; Endothelin-1;

1999
[Contemporary rules for diagnosing hypertension].
    Polskie Archiwum Medycyny Wewnetrznej, 1999, Volume: 101, Issue:3

    Topics: Aldosterone; Biomarkers; Blood Vessels; Elasticity; Humans; Hypertension; P-Selectin; Renin

1999
Racial differences in response to acute dosing with hydrochlorothiazide.
    American journal of hypertension, 2000, Volume: 13, Issue:2

    Topics: Adult; Aldosterone; Black People; Blood Pressure; Circadian Rhythm; Diuretics; Dose-Response Relatio

2000
[Changes in gluco- and mineralocorticoid adrenal functions in rats with inherited arterial hypertension during experimental myocardial infarction].
    Biulleten' eksperimental'noi biologii i meditsiny, 2000, Volume: 129, Issue:1

    Topics: Adrenal Glands; Aldosterone; Animals; Corticosterone; Hypertension; Male; Myocardial Infarction; Rat

2000
Plasma aldosterone concentrations are not related to the degree of angiotensin-converting enzyme inhibition in essential hypertensive patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23, Issue:1

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Biomarkers; Blood Pressure; Ech

2000
Medical management of aldosterone-producing adenomas.
    Annals of internal medicine, 2000, Apr-04, Volume: 132, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension; Mineralocorticoid Receptor Anta

2000
Role of dietary potassium in the hyperaldosteronism and hypertension of the remnant kidney model.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:4

    Topics: Aldosterone; Animals; Blood Pressure; Circadian Rhythm; Glomerular Filtration Rate; Hyperaldosteroni

2000
Insulin action in primary hyperaldosteronism before and after surgical or pharmacological treatment.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2000, Volume: 108, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Glucose; Glucose Clamp Technique; Glucos

2000
Liddle's syndrome: a report in a middle-aged woman.
    Yonsei medical journal, 2000, Volume: 41, Issue:2

    Topics: Aldosterone; Alkalosis; Female; Humans; Hypertension; Hypokalemia; Middle Aged; Renin; Syndrome

2000
High prevalence of primary aldosteronism in the Tayside hypertension clinic population.
    Journal of human hypertension, 2000, Volume: 14, Issue:5

    Topics: Adult; Aged; Aldosterone; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hypertension; Male; M

2000
Defective suppression of the aldosterone biosynthesis during stroke permissive diet in the stroke-prone phenotype of the spontaneously hypertensive rat.
    Basic research in cardiology, 2000, Volume: 95, Issue:2

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Hypertension; Japan; Male; Rats; Rats, Inbred SHR;

2000
[Effect of coffee on blood pressure and activity renin-angiotensin- aldosterone system and catecholamines concentration in patients with essential hypertension].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1999, Volume: 7, Issue:40

    Topics: Adult; Aged; Aldosterone; Angiotensins; Caffeine; Catecholamines; Coffee; Humans; Hypertension; Male

1999
Primary hyperaldosteronism in essential hypertensives: prevalence, biochemical profile, and molecular biology.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:5

    Topics: Aldosterone; Blood Pressure; Crossing Over, Genetic; Cytochrome P-450 CYP11B2; Dexamethasone; Female

2000
Difficult-to-control hypertension.
    Mayo Clinic proceedings, 2000, Volume: 75, Issue:6

    Topics: Adrenal Gland Neoplasms; Aldosterone; Catecholamines; Diagnosis, Differential; Humans; Hypertension;

2000
Severity of hypertension in familial hyperaldosteronism type I: relationship to gender and degree of biochemical disturbance.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:6

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Circadian Rhythm; Cytochrome P-45

2000
Renin-angiotensin-aldosterone system in pregnancy-induced hypertension.
    Journal of human hypertension, 2000, Volume: 14 Suppl 1

    Topics: Adult; Aldosterone; Biomarkers; Blood Pressure; Female; Humans; Hypertension; Peptidyl-Dipeptidase A

2000
Different regulation of cardiac and renal corticosteroid receptors in aldosterone-salt treated rats: effect of hypertension and glucocorticoids.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:7

    Topics: Adrenalectomy; Age Factors; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blottin

2000
Premature closure or do not get lost in your diagnostic work-up and blame it on the patient.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2000, Volume: 15, Issue:7

    Topics: Adult; Aldosterone; Angiography; Diagnostic Errors; Diuretics; Female; Humans; Hypertension; Renal A

2000
Reversal of cardiac hypertrophy and fibrosis by S21402, a dual inhibitor of neutral endopeptidase and angiotensin converting enzyme in SHRs.
    Journal of hypertension, 2000, Volume: 18, Issue:6

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cardiomeg

2000
Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy.
    Science (New York, N.Y.), 2000, Jul-07, Volume: 289, Issue:5476

    Topics: Adolescent; Aldosterone; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Binding, Compe

2000
Delayed hypotensive effect of the thromboxane A2/prostaglandin H2 receptor antagonist S-1452 in spontaneously hypertensive rats.
    Clinical and experimental pharmacology & physiology, 2000, Volume: 27, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Bridged

2000
[Mechanism of primary hypertension].
    Harefuah, 1998, Jun-01, Volume: 134, Issue:11

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Aldosterone; Animals; Corticosterone; Humans; Hydroxyst

1998
Molecular variations in the calcium-sensing receptor in relation to sodium balance and presence of hypertension in blacks and whites.
    American journal of hypertension, 2000, Volume: 13, Issue:6 Pt 1

    Topics: Adolescent; Adult; Aldosterone; Black People; Blood Pressure; Blood Pressure Monitoring, Ambulatory;

2000
Genetic variation of the gamma subunit of the epithelial Na+ channel and essential hypertension. Relationship with salt sensitivity.
    American journal of hypertension, 2000, Volume: 13, Issue:6 Pt 1

    Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Monitoring, Ambulatory; DNA; DNA Primers; Epithel

2000
[Incidence of primary hyperaldosteronism in hospitalized patients with hypertension].
    Bratislavske lekarske listy, 1999, Volume: 100, Issue:4

    Topics: Adult; Aldosterone; Female; Hospitalization; Humans; Hyperaldosteronism; Hypertension; Male; Middle

1999
Hypertension. Mutation points to salt recycling pathway.
    Science (New York, N.Y.), 2000, Jul-07, Volume: 289, Issue:5476

    Topics: Aldosterone; Female; Humans; Hypertension; Kidney; Male; Point Mutation; Pregnancy; Pregnancy Compli

2000
Prevalence of primary aldosteronism among Asian hypertensive patients in Singapore.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:8

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; China; Female; Humans; Hyperaldos

2000
[Response of vasoactive substance to blood pressure changes during hemodialysis in uremic patients].
    Polskie Archiwum Medycyny Wewnetrznej, 1999, Volume: 102, Issue:3

    Topics: Aldosterone; Atrial Natriuretic Factor; Blood Volume; Female; Humans; Hypertension; Male; Nitric Oxi

1999
Child abuse in an infant presenting as unexplained acute systemic hypertension.
    Pediatric nephrology (Berlin, Germany), 2000, Volume: 14, Issue:8-9

    Topics: Acute Disease; Aldosterone; Antihypertensive Agents; Blood Pressure; Captopril; Child Abuse; Femoral

2000
The aldosterone/renin ratio as a screening test for primary aldosteronism.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2000, Volume: 90, Issue:4

    Topics: Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension; Male;

2000
[What tests should be conducted for secondary arterial hypertension in hypertensive patients resistant to treatment?].
    Archives des maladies du coeur et des vaisseaux, 2000, Volume: 93, Issue:8

    Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Cohort Studies; Drug Combinations; Follo

2000
Renin inhibition improves pressure natriuresis in essential hypertension.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:10

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Imidazoles; Male; Middle

2000
Role of salt in hypertensive left venticular diastolic function.
    American heart journal, 2000, Volume: 140, Issue:4

    Topics: Aldosterone; Blood Flow Velocity; Diastole; Echocardiography, Doppler, Color; Heart Ventricles; Huma

2000
Roles of renal dopamine and kallikrein-kinin systems in antihypertensive mechanisms of exercise in rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23, Issue:5

    Topics: Aldosterone; Animals; Aromatic-L-Amino-Acid Decarboxylases; Blood Pressure; Blotting, Northern; Body

2000
Circadian rhythms in the renin-angiotensin system and adrenal steroids may contribute to the inverse blood pressure rhythm in hypertensive TGR(mREN-2)27 rats.
    Chronobiology international, 2000, Volume: 17, Issue:5

    Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Animals, Genetically Modified; Blood Pressure; Circad

2000
Cardiac aldosterone production in genetically hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:4

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardi

2000
Hypertension associated with multiple renal arteries may be renin-dependent.
    Journal of hypertension, 2000, Volume: 18, Issue:10

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Female; Furosemide; Humans; Hypertension; Male; Middl

2000
[Role of hypothalamo-hypophyseal-adrenal axis in the pathogenesis of arterial hypertension in patients with prolactinoma of the anterior lobe of the hypophysis].
    Terapevticheskii arkhiv, 2000, Volume: 72, Issue:9

    Topics: Adult; Aldosterone; Bromocriptine; Data Interpretation, Statistical; Dopamine; Dopamine Agonists; Fe

2000
Dexamethasone-suppressible hypertension.
    Lancet (London, England), 2000, Aug-26, Volume: 356, Issue:9231

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Dexamethasone; Female; Genotype; Glucocor

2000
Nephrocalcinosis and renal cysts associated with apparent mineralocorticoid excess syndrome.
    Pediatric nephrology (Berlin, Germany), 2000, Volume: 15, Issue:1-2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adolescent; Aldosterone; Alkalosis; Female; Humans; Hydroxyst

2000
The urinary levels of catecholamines, aldosterone and cortisol in hypertensive East Africans: a pilot study.
    Ethnicity & disease, 2000,Autumn, Volume: 10, Issue:3

    Topics: Adolescent; Aldosterone; Catecholamines; Female; Humans; Hydrocortisone; Hypertension; Kenya; Male;

2000
Prenatal programming of adult hypertension in the rat.
    Kidney international, 2001, Volume: 59, Issue:1

    Topics: Aging; Aldosterone; Animals; Apoptosis; Blood Pressure; Creatine; Dietary Proteins; Female; Fetal Gr

2001
[The autonomic nervous system and hypertension: quid novi?].
    Archives des maladies du coeur et des vaisseaux, 2000, Volume: 93, Issue:11 Suppl

    Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Humans; Hypertension

2000
Serum aldosterone changes during hyperinsulinemia are correlated to body mass index and insulin sensitivity in patients with essential hypertension.
    Journal of hypertension, 2001, Volume: 19, Issue:1

    Topics: Aldosterone; Biomarkers; Blood Glucose; Blood Pressure; Body Mass Index; Calcium; Disease Progressio

2001
The renin-aldosterone system during normal and hypertensive pregnancy.
    Archives of gynecology and obstetrics, 2001, Volume: 264, Issue:4

    Topics: Adult; Aldosterone; Birth Weight; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy

2001
Two sporadic cases of Liddle's syndrome caused by De novo ENaC mutations.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 37, Issue:3

    Topics: Adult; Aldosterone; Epithelium; Female; Humans; Hypertension; Hypokalemia; Male; Mutation, Missense;

2001
Approach to the patient with hypertension, unexplained hypokalemia, and metabolic alkalosis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 37, Issue:3

    Topics: Adenoma; Adrenalectomy; Aldosterone; Alkalosis; Antihypertensive Agents; Diagnosis, Differential; Hu

2001
Antifibrotic effects of N-acetyl-seryl-aspartyl-Lysyl-proline on the heart and kidney in aldosterone-salt hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cell Division; Colla

2001
A mutation in the cofactor-binding domain of 11beta-hydroxysteroid dehydrogenase type 2 associated with mineralocorticoid hypertension.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Amino Acid Sequence; Binding Sites; Cell Line; C

2001
Arterial pressure, left ventricular mass, and aldosterone in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:3

    Topics: Adult; Aldosterone; Black People; Blood Pressure; Body Mass Index; Canada; Circadian Rhythm; Electro

2001
Effect of sympathetic and plasma renin activity on hemodialysis hypertension.
    Clinical nephrology, 2001, Volume: 55, Issue:2

    Topics: Adult; Aldosterone; Chromatography, High Pressure Liquid; Epinephrine; Female; Humans; Hypertension;

2001
Screening for primary aldosteronism without discontinuing hypertensive medications: plasma aldosterone-renin ratio.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 37, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Antihypertensive Agents; Female; Humans; Hyper

2001
Hormone replacement therapy increases plasma level of angiotensin II in postmenopausal hypertensive women.
    American journal of hypertension, 2001, Volume: 14, Issue:3

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Bradykinin; Female; Hormone Replacement Therapy; Humans;

2001
The role of nitric oxide and the renin-angiotensin system in salt-restricted Dahl rats.
    American journal of hypertension, 2001, Volume: 14, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Diet, Sodium-Restricted; Down-Regulation; Glucuronidase; Hyper

2001
Cautions over the current epidemic of primary aldosteronism.
    Lancet (London, England), 2001, Mar-24, Volume: 357, Issue:9260

    Topics: Aldosterone; Diagnostic Errors; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Renin

2001
Twenty-Four hour blood pressure profile in subjects with different subtypes of primary aldosteronism.
    Physiological research, 2001, Volume: 50, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Pressure; Blood Pressure Determination;

2001
Aldosterone to renin ratio as a determinant of exercise blood pressure response in hypertensive patients.
    Journal of human hypertension, 2001, Volume: 15, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Determination; Exercise; Exercise Test; Female; H

2001
Salt sensitivity in genetically hypertensive rats of the Lyon strain.
    Kidney international, 2001, Volume: 59, Issue:5

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Press

2001
Effects of high sodium intake on cardiovascular aldosterone synthesis in stroke-prone spontaneously hypertensive rats.
    Journal of hypertension, 2001, Volume: 19, Issue:3 Pt 2

    Topics: Aldosterone; Animals; Cardiovascular System; Diet; Genetic Predisposition to Disease; Hypertension;

2001
[Excess of mineralocorticoids in essential hypertension: clinical-diagnostic approach].
    Revista medica de Chile, 2000, Volume: 128, Issue:9

    Topics: Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potas

2000
Paraneoplastic hyperaldosteronism associated with non-Hodgkin's lymphoma.
    The New England journal of medicine, 2001, May-17, Volume: 344, Issue:20

    Topics: Aldosterone; Cytochrome P-450 CYP11B2; Fatal Outcome; Humans; Hyperaldosteronism; Hypertension; Lymp

2001
Diagnosis of Liddle syndrome by genetic analysis of beta and gamma subunits of epithelial sodium channel--a report of five affected family members.
    Journal of hypertension, 2001, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Aged; Aldosterone; Base Sequence; Child; DNA; Epithelial Sodium Channels; Female;

2001
ET(A) receptor antagonist prevents blood pressure elevation and vascular remodeling in aldosterone-infused rats.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:6

    Topics: Aldosterone; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Body Weight; Dansyl Compounds;

2001
Insulin, renin-aldosterone system and blood pressure in obese people.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2001, Volume: 25, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Cross-Sectional Studies; Female; Humans; Hyperinsulinism; Hypert

2001
Chronic treatment with amlodipine modulates adrenocortical angiotensin II receptors in spontaneously hypertensive rats.
    Life sciences, 2001, May-25, Volume: 69, Issue:1

    Topics: Adrenal Cortex; Aldosterone; Amlodipine; Animals; Antihypertensive Agents; Hypertension; Male; Rats;

2001
Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease.
    The Journal of biological chemistry, 2001, Sep-28, Volume: 276, Issue:39

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Antioxidants; Bl

2001
Insulin sensitivity and sodium excretion in normotensive offspring and hypertensive patients.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:8

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Insulin; Insulin Resistance; Male; Norepinephrine;

2001
A family with liddle's syndrome caused by a mutation in the beta subunit of the epithelial sodium channel.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2001, Volume: 23, Issue:6

    Topics: Aldosterone; Alkalosis; Base Sequence; Blood Gas Analysis; Calcium Channel Blockers; Diagnosis, Diff

2001
Cautions over idiopathic aldosteronism.
    Lancet (London, England), 2001, Jul-28, Volume: 358, Issue:9278

    Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension

2001
Prevalence of primary aldosteronism in unselected hypertensive populations: screening and definitive diagnosis.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:8

    Topics: Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Mass Screening; Pota

2001
Mineralocorticoids upregulate arterial contraction to epidermal growth factor.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:3

    Topics: Aldosterone; Animals; Aorta, Thoracic; Blood Pressure; Desoxycorticosterone; Dose-Response Relations

2001
Primary aldosteronism: factors associated with normalization of blood pressure after surgery.
    Annals of internal medicine, 2001, Aug-21, Volume: 135, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aged, 80 and over; Aldosterone; Analys

2001
Lack of association between Gly460Trp polymorphism of alpha-adducin gene and salt sensitivity of blood pressure in Polish hypertensives.
    Kidney & blood pressure research, 2001, Volume: 24, Issue:3

    Topics: Adult; Aldosterone; Amino Acid Sequence; Blood Pressure; Calmodulin-Binding Proteins; Diet, Sodium-R

2001
Screening for primary aldosteronism--normal ranges for aldosterone and renin in three South African population groups.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2001, Volume: 91, Issue:7

    Topics: Aldosterone; Ethnicity; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Prevale

2001
Adrenal response to angiotensin II in black hypertension: lack of sexual dimorphism.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3

    Topics: Adrenal Glands; Adult; Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Black People; Fema

2001
Hemodynamic and metabolic profile in offspring of malignant hypertensive parents.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3 Pt 2

    Topics: Adolescent; Adult; Aldosterone; Blood Glucose; Blood Pressure; Cholesterol; Diastole; Family Health;

2001
A new role for progesterone: an agonist for mineralocorticoid receptor activation and pregnancy-related hypertension.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 38, Issue:4

    Topics: Aldosterone; Codon, Nonsense; Female; Heterozygote; Humans; Hypertension; Pregnancy; Pregnancy Compl

2001
-344C/T polymorphism of CYP11B2 gene in Italian patients with idiopathic low renin hypertension.
    American journal of hypertension, 2001, Volume: 14, Issue:9 Pt 1

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cytochrome P-450 CYP11B2; Gene Fre

2001
Enrasentan improves survival, limits left ventricular remodeling, and preserves myocardial performance in hypertensive cardiac hypertrophy and dysfunction.
    Journal of cardiovascular pharmacology, 2001, Volume: 38, Issue:4

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Carboxylic Acids; Endothelin Recept

2001
Adverse cardiac effects of salt with fludrocortisone in hypertension.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:4

    Topics: Aldosterone; Anti-Inflammatory Agents; Blood Pressure; Echocardiography; Electrocardiography; Fludro

2001
Role of renin-angiotensin-aldosterone system in salt-sensitive hypertension induced by sensory denervation.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:5

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Capsaicin; Denervation; Female; Hypertension; Min

2001
Insulin sensitivity with respect to glucose metabolism in hypertension-prone men did not predict the blood pressure increase in 5 years.
    Journal of human hypertension, 2001, Volume: 15, Issue:11

    Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Body Mass Index; Family Health; Follow-Up Studies

2001
Role of angiotensin converting enzyme genotype in sodium sensitivity in older hypertensives.
    American journal of hypertension, 2001, Volume: 14, Issue:12

    Topics: Aged; Aging; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Genotype; Humans; Hyperte

2001
Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension.
    Journal of hypertension, 2002, Volume: 20, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Dose-Response Relationship, Drug; Family Health; Germany; Hemody

2002
[Study on the relation between hypertensive left ventricular hypertrophy in very old people with neurohormonal factors and ventricular arrhythmias].
    Zhonghua nei ke za zhi, 2000, Volume: 39, Issue:12

    Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Arrhythmias, Cardiac; Female; Humans; Hyperten

2000
Left ventricular structure and diastolic function in subjects with two hypertensive parents.
    Blood pressure, 2001, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Case-Control Studies; Catecholamines

2001
Normokalemic hyperaldosteronism in patients with resistant hypertension.
    The Israel Medical Association journal : IMAJ, 2002, Volume: 4, Issue:1

    Topics: Adult; Aged; Aldosterone; Analysis of Variance; Antihypertensive Agents; Creatinine; Female; Humans;

2002
Primary aldosteronism: the most frequent form of secondary hypertension?
    The Israel Medical Association journal : IMAJ, 2002, Volume: 4, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Mineral

2002
Effects of long-term enalapril and losartan therapy of hypertension on cardiovascular aldosterone.
    Hormone research, 2001, Volume: 55, Issue:6

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit

2001
Salt-sensitive hypertension resulting from nitric oxide synthase inhibition is associated with loss of regulation of angiotensin II in the rat.
    Experimental physiology, 2002, Volume: 87, Issue:1

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Enzyme Inhibit

2002
Test and teach. Surgically correctable hypertension. Conn's syndrome and spironolactone bodies.
    Pathology, 2001, Volume: 33, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertens

2001
Mutations in aldosterone synthase gene of Milan hypertensive rats: phenotypic consequences.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:3

    Topics: 18-Hydroxycorticosterone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldo

2002
Role of aldosterone in the pathogenesis of hypertension.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:2

    Topics: Aldosterone; Blood Pressure; Cytochrome P-450 CYP11B2; Exercise; Humans; Hypertension; Quantitative

2002
Hypertension due to a giant aldosterone-secreting adenoma.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2001, Volume: 2, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Female; Humans; Hypertension; Middle Aged; Tomograph

2001
Upregulation of arterial serotonin 1B and 2B receptors in deoxycorticosterone acetate-salt hypertension.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:2 Pt 2

    Topics: Aldosterone; Animals; Desoxycorticosterone; Gene Expression; Hypertension; Male; Mineralocorticoids;

2002
Effects of losartan and benazepril on abnormal circadian blood pressure rhythm and target organ damage in SHRSP.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2002, Volume: 24, Issue:3

    Topics: Aldosterone; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Cardiomegaly; Circadian

2002
Is primary aldosteronism underdiagnosed in clinical practice?
    Clinical and experimental pharmacology & physiology, 2001, Volume: 28, Issue:12

    Topics: Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Diagnosis, Differential; Humans; Hyperaldostero

2001
Dysregulation of angiotensin II synthesis is associated with salt sensitivity in the spontaneous hypertensive rat.
    Acta physiologica Scandinavica, 2002, Volume: 174, Issue:3

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting

2002
[Hypertension: once primary, always primary?].
    Nederlands tijdschrift voor geneeskunde, 2002, Mar-09, Volume: 146, Issue:10

    Topics: Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Female; Humans; Hyperaldosteron

2002
Primary aldosteronism in normokalemic patients with adrenal incidentalomas.
    European journal of endocrinology, 2002, Volume: 146, Issue:4

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Fe

2002
Influence of plasma aldosterone on left ventricular geometry and diastolic function in treated essential hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2002, Volume: 25, Issue:1

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Diastole; Echocardiography; Female; Heart Vent

2002
Ratio of serum aldosterone to plasma renin concentration in essential hypertension and primary aldosteronism.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2002, Volume: 110, Issue:2

    Topics: Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Prosp

2002
Combination of non-hypotensive doses of valsartan and enalapril improves survival of spontaneously hypertensive rats with endothelial dysfunction.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2000, Volume: 1, Issue:2

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Press

2000
The role of spironolactone in the treatment of patients with refractory hypertension.
    American journal of hypertension, 2002, Volume: 15, Issue:4 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Mid

2002
Stress-induced renal alterations in normotensives offspring of hypertensives and in hypertensives.
    American journal of hypertension, 2002, Volume: 15, Issue:4 Pt 1

    Topics: Aldosterone; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Renin; Sodium;

2002
Aldosterone is produced from ventricles in patients with essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:5

    Topics: Aldosterone; Analysis of Variance; Atrial Natriuretic Factor; Blood Pressure; Female; Heart Ventricl

2002
Unilateral adrenal hyperplasia causing primary aldosteronism: limitations of I-131 norcholesterol scanning.
    American journal of hypertension, 2002, Volume: 15, Issue:5

    Topics: Adosterol; Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; Iodin

2002
Aldosterone acts on the kidney, not the brain, to cause mineralocorticoid hypertension in sheep.
    Journal of hypertension, 2002, Volume: 20, Issue:6

    Topics: Aldosterone; Animals; Blood; Blood Pressure; Body Fluids; Brain; Electrolytes; Female; Hormones; Hyp

2002
Comparison of circulating and local adipose tissue renin-angiotensin system in normotensive and hypertensive obese subjects.
    Journal of endocrinological investigation, 2002, Volume: 25, Issue:4

    Topics: Adipose Tissue; Adult; Aldosterone; Angiotensinogen; Blood; Female; Humans; Hypertension; Male; Midd

2002
Effects of hormone replacement therapy on left ventricular hypertrophy and growth-promoting factors in hypertensive postmenopausal women.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2002, Volume: 25, Issue:2

    Topics: Aldosterone; Echocardiography; Estrogen Replacement Therapy; Female; Growth Substances; Humans; Hype

2002
Aldosterone excess and essential hypertension.
    Journal of human hypertension, 2002, Volume: 16, Issue:7

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension

2002
Renin-producing serous cystoadenocarcinoma of the ovary: a case report.
    European journal of gynaecological oncology, 2002, Volume: 23, Issue:3

    Topics: Aldosterone; Cystadenocarcinoma, Serous; Diagnosis, Differential; Female; Humans; Hyperaldosteronism

2002
Excess aldosterone is associated with alterations of myocardial texture in primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:1

    Topics: Adult; Aged; Aldosterone; Echocardiography, Doppler; Female; Heart; Heart Ventricles; Humans; Hypera

2002
Aldosterone breakthrough during angiotensin II receptor antagonist therapy in stroke-prone spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:1

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals;

2002
[Effect of chronic beta-receptor blockade in blood pressure and renin and aldosterone secretion in essential hypertension].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1975, Volume: 81

    Topics: Adrenergic beta-Antagonists; Aldosterone; Blood Pressure; Humans; Hypertension; Renin

1975
Long term treatment of moderate hypertension with penbutolol (Hoe 893d). I. Effects on blood pressure, pulse rate, catecholamines in blood and urine, plasma renin activity and urinary aldosterone under basal conditions and following exercise.
    European journal of clinical pharmacology, 1975, Oct-10, Volume: 9, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Cyclopentanes

1975
Renin and age as determinants of a predominantly betablocker-based antihypertensive drug program.
    Advances in nephrology from the Necker Hospital, 1976, Volume: 6

    Topics: Adrenergic beta-Antagonists; Adult; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Blo

1976
Labetalol (AH5158), a competitive alpha- and beta-receptor blocking drug, in the management of hypertension.
    Australian and New Zealand journal of medicine, 1976, Volume: 6, Issue:3 Suppl

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Cloni

1976
Clonidine and the vasodilating beta blocker antihypertensive drug interaction.
    Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Clonidine; Drug Interactions; Femal

1977
Mineralocorticoid radioreceptor assay: application to adrenal-regeneration hypertension.
    Life sciences, 1977, Oct-01, Volume: 21, Issue:7

    Topics: Adrenal Glands; Aldosterone; Animals; Cytosol; Hydrogen-Ion Concentration; Hypertension; Mineralocor

1977
[Recurrent aldosteronism and arterial hypertension following adrenalectomy. One clinical case (author's transl)].
    Annales d'endocrinologie, 1978, Volume: 39, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Adrenergic beta-Antagonists; Adult; Aldosterone; Humans; Hyperaldoste

1978
Need for beta-blockade in hypertension reduced with long-term minoxidil.
    British medical journal, 1978, Aug-05, Volume: 2, Issue:6134

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Female; Follow-Up Studies; Humans; Hypertension; Ma

1978
Symposium: Renin-angiotensin-aldosterone system and hypertension.
    Klinische Wochenschrift, 1978, Volume: 56 Suppl 1

    Topics: Aldosterone; Angiotensin II; Animals; Congresses as Topic; Germany, West; Humans; Hypertension; Reni

1978
[Hormone and mediator content in the blood of the adrenals and in the peripheral blood in hypertension].
    Kardiologiia, 1979, Volume: 19, Issue:12

    Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adult

1979
[Behavior of cardiac output, plasma volume, plasma renin activity and aldosterone secretion in patients with essential hypertension treated with beta-blocking agents and diuretics].
    La Clinica terapeutica, 1979, Aug-15, Volume: 90, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Volume; Cardiac Output; Chlorthalidone; Diure

1979
Is low-renin hypertension a stage in the development of essential hypertension or a diagnostic entity?
    Lancet (London, England), 1975, Mar-08, Volume: 1, Issue:7906

    Topics: Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Blood Specimen Collection; Female; Humans; Hy

1975
Severe arterial hypertension caused by chronical abuse of a topical mineralocorticoid.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Adult; Aldosterone; Clonidine; Drug Combinations; Drug Therapy, Combination; Female; Fluprednisolone

1975
Rectal potential difference in essential hypertension.
    Lancet (London, England), 1976, Jun-12, Volume: 1, Issue:7972

    Topics: Action Potentials; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Rectum; Renin

1976
Dexamethasone-responsive hypertension in young women with suppressed renin and aldosterone.
    Lancet (London, England), 1978, Apr-08, Volume: 1, Issue:8067

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure; Body Weight; Dexamethasone; Female;

1978
Active and total renin in physiological and pathophysiological conditions [proceedings].
    Archives internationales de physiologie et de biochimie, 1977, Volume: 85, Issue:5

    Topics: Age Factors; Aldosterone; Humans; Hypertension; Renin; Sodium

1977
A renal abnormality as a possible cause of "essential" hypertension.
    Lancet (London, England), 1979, Jan-27, Volume: 1, Issue:8109

    Topics: Adult; Aldosterone; Animals; Blood Pressure; Cardiac Output; Catecholamines; Female; Glomerular Filt

1979
Influence of beta blockade on the renin-angiotensin-aldosterone system [proceedings].
    Archives internationales de physiologie et de biochimie, 1979, Volume: 87, Issue:1

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Metoprolol; Propanolamines; Propranolol; Renin

1979
Idiopathic aldosteronism: a diagnostic artifact?
    Lancet (London, England), 1979, Dec-08, Volume: 2, Issue:8154

    Topics: Aldosterone; Angiotensin II; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Reni

1979
Evidence for a new mineralocorticoid in patients with low-renin essential hypertension.
    Circulation research, 1975, Volume: 36, Issue:6 Suppl 1

    Topics: Adrenalectomy; Aldosterone; Animals; Biological Assay; Chromatography, Gas; Corticosterone; Cortison

1975
The Distinguished Lecture. Is hypertension essential?
    Transactions of the Association of American Physicians, 1975, Volume: 88

    Topics: Aldosterone; Aminoglutethimide; Angiotensin II; Animals; Dehydroepiandrosterone; Humans; Hypertensio

1975
Interaction of 16beta-hydroxydehydroepiandrosterone with renal mineralocorticoid receptors.
    The Journal of laboratory and clinical medicine, 1977, Volume: 89, Issue:2

    Topics: Aldosterone; Animals; Binding, Competitive; Dehydroepiandrosterone; Hypertension; Kidney; Male; Mine

1977
Pathogenic significance of adrenocortical hormones in essential hypertension.
    Japanese circulation journal, 1977, Volume: 41, Issue:3

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Aldosterone; Cortodoxone; Dehydroepiandrost

1977
Hypertension, hypokalemia, hyporeninemia and severe target organ damage.
    Canadian Medical Association journal, 1976, Feb-07, Volume: 114, Issue:3

    Topics: Aldosterone; Blood Pressure; Cardiomegaly; Female; Humans; Hyperaldosteronism; Hypertension; Hypokal

1976
[Comparative study of plasma levels of renin and aldosterone activity in essential arterial hypertension in relation to duration of the disease and the presence of complications].
    Bollettino della Societa italiana di cardiologia, 1977, Volume: 22, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aldosterone; Cardiomegaly; Chronic Disease; Female; Humans; Hypert

1977
A case of ectopic renin-secreting orbital hemangiopericytoma associated with juvenile hypertension and hypokalemia.
    Acta medica Okayama, 1979, Volume: 33, Issue:4

    Topics: Adolescent; Aldosterone; Brain; Brain Neoplasms; Exophthalmos; Female; Hemangiopericytoma; Humans; H

1979
Plasma renin activity and in vitro synthesis of aldosterone by the adrenal glands of rats with spontaneous, renal, or pinealectomy-induced hypertension.
    Acta physiologica Scandinavica, 1975, Volume: 94, Issue:2

    Topics: Adenosine Monophosphate; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pr

1975
Dynamic aldosterone and 18-hydroxydeoxycorticosterone studies in labile and stable benign essential hypertension.
    Journal of steroid biochemistry, 1975, Volume: 6, Issue:5

    Topics: 18-Hydroxydesoxycorticosterone; Adrenocorticotropic Hormone; Aldosterone; Carrier Proteins; Circadia

1975
Enhanced aldosterone response to angiotensin II in human hypertension.
    Circulation research, 1976, Volume: 38, Issue:6

    Topics: Adrenal Cortex; Adrenal Glands; Adult; Aldosterone; Analysis of Variance; Angiotensin II; Female; Hu

1976
The regulation of plasma 18-hydroxy 11-deoxycorticosterone in man.
    The Journal of clinical investigation, 1976, Volume: 58, Issue:1

    Topics: 18-Hydroxydesoxycorticosterone; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Des

1976
Unusual low plasma renin hypertension in a child.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 43, Issue:2

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Alkalosis;

1976
[State of the renal-pressor units of arterial pressure regulation in primary arterial hypertension in children and adolescents].
    Pediatriia, 1976, Issue:2

    Topics: Adolescent; Adrenal Cortex; Adrenal Glands; Aldosterone; Child; Endopeptidases; Humans; Hypertension

1976
Aldosterone receptors and the evaluation of plasma mineralocorticoid activity in normal and hypertensive states.
    The Journal of clinical investigation, 1976, Volume: 58, Issue:3

    Topics: Aldosterone; Androstenediols; Animals; Binding, Competitive; Corticosterone; Depression, Chemical; D

1976
The role of ACTH in the episodic release of aldosterone in patients with idiopathic adrenal hyperplasia, hypertension, and hyperaldosteronism.
    The Journal of laboratory and clinical medicine, 1976, Volume: 88, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Depressi

1976
Plasma deoxycorticosterone and aldosterone in essential hypertension.
    Journal of steroid biochemistry, 1976, Volume: 7

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Desoxycorticosterone; Female; Humans; Hypertension;

1976
The mechanism of low-renin hypertension: aldosterone response to sodium restriction and upright posture, angiotensin II, ACTH and potassium in patients with hypertension.
    Japanese circulation journal, 1976, Volume: 40, Issue:8

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensin II; Diet; Female; Humans; Hydroco

1976
Effects of ACTH on plasma levels of adrenal steroids in essential hypertension.
    Endocrinologia japonica, 1976, Volume: 23, Issue:3

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure; Corticoste

1976
[Changes of the renin-angiotensin-aldosterone system under contraceptive steroids. Contribution to the etiology of hypertension under hormonal contraceptives].
    Fortschritte der Medizin, 1976, Nov-18, Volume: 94, Issue:33

    Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Endopeptid

1976
Evidence for an unidentified ACTH-induced steroid hormone causing hypertension.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 43, Issue:6

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldoste

1976
[State of the neurohumoral regulatory system in circulatory insufficiency].
    Kardiologiia, 1976, Volume: 16, Issue:12

    Topics: 17-Ketosteroids; Adult; Aged; Aldosterone; Angiotensinogen; Coronary Disease; Cortisone; Endopeptida

1976
Endocrine and cardiovascular consequences of angiotensin converting enzyme inhibition.
    The Journal of international medical research, 1977, Volume: 5, Issue:1

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Dose-Response Relationship, D

1977
Response of several adrenal steroids to ACTH stimulation in essential hypertension.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Corticoste

1977
Unexpected pressor responses to propranolol in essential hypertension. An interaction between renin, aldosterone and sympathetic activity.
    The American journal of medicine, 1976, May-31, Volume: 60, Issue:6

    Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Body Weight; Depression, Chemical; Female; Heart Ra

1976
Blockade of renin or angiotensin for understanding human hypertension: a comparison of propranolol, saralasin and converting enzyme blockade.
    Federation proceedings, 1977, Volume: 36, Issue:5

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Volume;

1977
The role of the adrenal cortex in human essential hypertension: keynote address.
    Mayo Clinic proceedings, 1977, Volume: 52, Issue:5

    Topics: 18-Hydroxydesoxycorticosterone; Adolescent; Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Horm

1977
[Do aldosterone and other mineralocorticoids play a role in the pathogenesis of essential hypertension?].
    L'union medicale du Canada, 1977, Volume: 106, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Proteins; Cir

1977
Plasma concentration of aldosterone, 18-hydroxy-deoxycorticosterone and cortisol in adrenal veins of patients with low-renin hypertension.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1977, Volume: 9, Issue:5

    Topics: 18-Hydroxydesoxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropi

1977
Effects of ACTH and posture on aldosterone metabolism in essential hypertension.
    Journal of steroid biochemistry, 1977, Volume: 8, Issue:12

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Po

1977
[2 models of indomethacin-induced arterial hypertension in rats in chronic experiments].
    Kardiologiia, 1977, Volume: 17, Issue:10

    Topics: Aldosterone; Angiotensins; Animals; Cyclic AMP; Disease Models, Animal; Hypertension; Indomethacin;

1977
[Primary hyperaldosteronism with paroxysmal arterial hypertension. Apropos of 2 operated cases].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1978, Jan-09, Volume: 54, Issue:2

    Topics: Adrenal Glands; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Mi

1978
Plasma levels of 18-hydroxy-11-deoxycorticosterone in essential hypertension.
    Endocrinologia japonica, 1978, Volume: 25, Issue:3

    Topics: 18-Hydroxydesoxycorticosterone; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Cir

1978
Mineralocorticoids, salt balance and blood pressure after prolonged ACTH administration in juvenile hypertension.
    Klinische Wochenschrift, 1978, Volume: 56 Suppl 1

    Topics: Adolescent; Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Body Weight; Child; Humans; Hy

1978
[Effect of varied sodium intake on the excretion of desoxycorticosterone, cortisol and aldosterone as well as the ACTH stimulation of those corticoids].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Cortisone; Desoxycorticosterone;

1978
The adrenal receptor for angiotensin II is altered in essential hypertension.
    The Journal of clinical investigation, 1979, Volume: 63, Issue:3

    Topics: Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors;

1979
Effect of angiotensin converting enzyme inhibition on blood pressure, plasma renin activity and plasma aldosterone in essential hypertension.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:2

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Female; Humans; Hypert

1978
Effect of posture on the plasma concentrations of aldosterone in hypertension and primary hyperaldosteronism.
    Nephron, 1979, Volume: 23, Issue:2-3

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Circadian Rhythm; Desoxycorticost

1979
Adrenocortical function, electrolyte metabolism, and blood pressure during prolonged adrenocorticotropin infusion in juvenile hypertension.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 49, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure

1979
Orally active angiotensin-converting enzyme inhibitor (SO 14,225) as a treatment for essential hypertension.
    British journal of clinical pharmacology, 1979, Volume: 7 Suppl 2

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Female; Humans; Hypert

1979
Reduced response of plasma aldosterone to acute ACTH stimulation during long-term treatment with spironolactone in essential hypertension.
    Hormone research, 1979, Volume: 11, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Blood Pressure; Humans; Hydrochlorothiazide; Hydroc

1979
Plasma aldosterone response to ACTH in primary aldosteronism and in patients with low renin hypertension.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldost

1978
The biologic significance of the aldosterone concentration in saliva.
    Pediatric research, 1979, Volume: 13, Issue:6

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Child; Child, Preschool; Dexamethasone;

1979
A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 49, Issue:5

    Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Aldosterone; Child; Cortisone; Humans; Hydro

1979
Adrenocortical steroid hormones in production of hypertension in sheep.
    Journal of steroid biochemistry, 1979, Volume: 11, Issue:1C

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure; Cardiac

1979
[A study on the mechanism of aldosterone secretion in low-renin essential hypertension (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1979, Oct-20, Volume: 55, Issue:10

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Electrolytes; Female; Furosemide; H

1979
Effects of chronic treatment with captopril (SQ 14,225), an orally active inhibitor of angiotensin I-converting enzyme, in spontaneously hypertensive rats.
    Japanese journal of pharmacology, 1979, Volume: 29, Issue:2

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Heart; Hy

1979
Humoral effects of the oral converting-enzyme inhibitor SQ 14,225 in hypertensive patients in supine and tilted position.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Epinephrine; Human

1979
A novel orally active converting-enzyme inhibitor YS 980: effects on blood pressure in spontaneously hypertensive rats.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: 3-Mercaptopropionic Acid; Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Anim

1979
Aldosterone and in vivo mineralocorticoid activity in normotensive and hypertensive man.
    Journal of the Royal Society of Medicine, 1979, Volume: 72, Issue:4

    Topics: Action Potentials; Adrenal Cortex Diseases; Aldosterone; Female; Humans; Hyperaldosteronism; Hyperte

1979
Urinary free 18-hydroxy-11-desoxycorticosterone excretion in normal and hypertensive patients.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:4

    Topics: 18-Hydroxydesoxycorticosterone; Adrenocorticotropic Hormone; Aldosterone; Desoxycorticosterone; Diet

1978
Rectal potential difference in the diagnosis of aldosterone excess.
    Gut, 1975, Volume: 16, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Desoxycorticosterone; Diet; Electrodes; Female;

1975
The effect of clonidine and penbutolol, respectively on catecholamines in blood and urine, plasma renin activity and urinary aldosterone in hypertensive patients.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 213, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Butylamines; Catecholamines; Clonidine; Cyclopentan

1975
Effects of dietary potassium and race on urinary excretion of kallikrein and aldosterone in man.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:2

    Topics: Adult; Aldosterone; Diet; Female; Humans; Hypertension; Kallikreins; Male; Middle Aged; Potassium; R

1978
[A precise bioassay for in vivo mineralocorticoid activity in man: relation to plasma aldosterone in normal subjects, essential hypertension, hyperaldosteronism and adrenocortical insufficiency (author transl)].
    Wiener klinische Wochenschrift. Supplementum, 1977, Volume: 78

    Topics: Adrenal Cortex Diseases; Aldosterone; Circadian Rhythm; Humans; Hyperaldosteronism; Hypertension; In

1977
Renin and aldosterone measurements in the diagnosis and management of hypertension. I. Renin and aldosterone measurements in the etiological diagnosis of hypertension.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1977, Volume: 76, Issue:11

    Topics: Adolescent; Adult; Aldosterone; Child; Child, Preschool; Female; Humans; Hypertension; Hypertension,

1977
Renin and aldosterone measurements in the diagnosis and management of hypertension. II. Renin and aldosterone measurements as guide of drug therapy in hypertension.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1977, Volume: 76, Issue:12

    Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin

1977
Clinical use of plasma renin assays.
    The New Zealand medical journal, 1978, Feb-08, Volume: 87, Issue:605

    Topics: Adolescent; Adrenal Gland Diseases; Adult; Aged; Aldosterone; Bartter Syndrome; Female; Humans; Hype

1978
Plasma aldosterone in essential hypertension.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1978, Volume: 77, Issue:2

    Topics: Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Sodium

1978
Renin, aldosterone, sodium and potassium in essential hypertension.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1978, Volume: 77, Issue:6

    Topics: Adolescent; Adult; Aged; Aldosterone; Humans; Hypertension; Male; Middle Aged; Potassium; Renin; Sod

1978
A physiological basis for the treatment of essential hypertension.
    Bulletin of the New York Academy of Medicine, 1978, Volume: 54, Issue:10

    Topics: Aldosterone; Clonidine; Diuretics; Humans; Hypertension; Propranolol; Renin; Sodium

1978
Acid-activated renin responses to hydrochlorothiazide, propranol and indomethacin.
    Clinical science and molecular medicine. Supplement, 1978, Volume: 4

    Topics: Adult; Aldosterone; Blood Pressure; Enzyme Activation; Humans; Hydrochlorothiazide; Hypertension; In

1978
The natural history of hypertension in turkeys.
    Clinical science and molecular medicine. Supplement, 1978, Volume: 4

    Topics: Aging; Aldosterone; Animals; Blood Pressure; Creatinine; Hypertension; Lipids; Potassium; Renin; Sod

1978
Evidence for an unidentified, adrenocorticotrophic hormone-dependent mineralocorticoid maintaining hypertension in young women with hypoaldosteronism.
    Clinical science and molecular medicine. Supplement, 1978, Volume: 4

    Topics: Adult; Aldosterone; Body Weight; Dexamethasone; Female; Humans; Hypertension; Hypokalemia; Renin

1978
Effects of labetalol on systemic and pulmonary haemodynamics at rest and during exercise in hypertensive patients.
    Clinical science and molecular medicine. Supplement, 1978, Volume: 4

    Topics: Adult; Aldosterone; Ethanolamines; Female; Hemodynamics; Humans; Hypertension; Labetalol; Male; Midd

1978
Renin--angiotensin system in mild essential hypertension. The functional significance of angiotensin II in untreated and thiazide-treated hypertensive patients.
    Clinical science and molecular medicine. Supplement, 1978, Volume: 4

    Topics: Adult; Aldosterone; Angiotensin II; Benzothiadiazines; Blood Pressure; Diuretics; Female; Humans; Hy

1978
The role of intrarenal vasoactive substances in the pathogenesis of essential hypertension.
    Clinical science and molecular medicine. Supplement, 1978, Volume: 4

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Female; Furosemide; H

1978
Noradrenaline secretion by the human kidney.
    Clinical science and molecular medicine. Supplement, 1978, Volume: 4

    Topics: Aging; Aldosterone; Blood Pressure; Humans; Hypertension; Kidney; Norepinephrine; Propranolol; Renin

1978
Haemodynamic and endocrinological profile of essential hypertension.
    Acta medica Scandinavica. Supplementum, 1978, Volume: 622

    Topics: Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Blood Volume; Cardiac Output; Extracellular S

1978
Effect of sodium loading on the renin-aldosterone system in essential hypertension.
    Acta medica Scandinavica. Supplementum, 1979, Volume: 625

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Male; Natriuresis; Renin; Sodium; Sodium Chloride

1979
Pathophysiological mechanisms of the antihypertensive effect of a cardioselective beta-adrenoceptor blocking drug (metoprolol).
    Acta medica Scandinavica. Supplementum, 1979, Volume: 625

    Topics: Aldosterone; Cardiac Output; Hemodynamics; Humans; Hypertension; Kidney; Male; Metoprolol; Middle Ag

1979
Renin angiotensin system and sympathetic nerve activity in mild essential hypertension. The functional significance of angiotensin II in untreated and thiazide treated hypertensive patients.
    Acta medica Scandinavica. Supplementum, 1979, Volume: 625

    Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle

1979
Measurement of the end-organ responses to aldosterone in man: diversity of response and its possible biological significance.
    Australian and New Zealand journal of medicine, 1979, Volume: 9, Issue:3

    Topics: Action Potentials; Adult; Aged; Aldosterone; Electrophysiology; Female; Humans; Hypertension; Kidney

1979
Intrinsic defect of aldosterone synthesis in dexamethasone-responsive hypertension with suppressed renin and aldosterone.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1979, Volume: 78, Issue:4

    Topics: Adult; Aldosterone; Dexamethasone; Female; Humans; Hydrocortisone; Hypertension; Renin

1979
"Outpatient hyperkalemia" syndrome in renal and hypertensive patients with suppressed aldosterone production.
    Journal of medicine, 1979, Volume: 10, Issue:3

    Topics: Adult; Aged; Aldosterone; Diet, Sodium-Restricted; Female; Humans; Hyperkalemia; Hypertension; Kidne

1979
[SAR1, ALA8]-Angiotensin II (saralasin): a symposium. Introduction.
    Kidney international. Supplement, 1979, Issue:9

    Topics: Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Hypertension, Renal; Renin; Saralasin

1979
[Mineralocorticoid hypertension: clinical and laboratory aspects with emphasis on selective percutaneous venography associated with aldosterone determination in the adrenal vein].
    AMB : revista da Associacao Medica Brasileira, 1977, Volume: 23, Issue:5

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Middle Aged; Mineralocorticoids; Phlebography; Pot

1977
[17 alpha-hydroxylase deficiency].
    Nihon rinsho. Japanese journal of clinical medicine, 1977,Spring, Volume: 35 Suppl 1

    Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Female; Humans; Hypertension; Hypogonadism; Male; Ster

1977
[Antihypertensive effect of carteolol, a beta-receptor blockader, in essential hypertension and its action on the renin-aldosterone system].
    Horumon to rinsho. Clinical endocrinology, 1977, Volume: 25, Issue:8

    Topics: Adolescent; Adult; Aged; Aldosterone; Antihypertensive Agents; Female; Humans; Hypertension; Levobun

1977
Plasma renin, plasma aldosterone and exchangeable sodium in normotensive and hypertensive kidney transplant recipients with and without transplant renal artery stenosis.
    Acta medica Scandinavica, 1977, Volume: 202, Issue:6

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Kidney Transplantation; Male; Middle Aged; Natriur

1977
Studies of renin-aldosterone axis in stable normotensive and hypertensive renal allograft recipients.
    Urology, 1978, Volume: 11, Issue:1

    Topics: Adult; Aldosterone; Creatinine; Female; Humans; Hypertension; Kidney Transplantation; Male; Postoper

1978
Role of the renin-angiotensin system in post-transplantation hypertension in patients with multiple kidneys.
    The New England journal of medicine, 1978, Jun-29, Volume: 298, Issue:26

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet; Female; Humans; Hypertension;

1978
Late hypertension following renal allotransplantation.
    Clinical nephrology, 1979, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Female; Follow-Up Studies; Humans; Hypertension; Hypertension, Renal

1979
Prolonged pseudoaldosteronism induced by glycyrrhizin.
    Endocrinologia japonica, 1979, Volume: 26, Issue:5

    Topics: Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Glycyrrhetinic Acid; Glycyrrhiza

1979
Effects of an angiotensin II antagonist; [sarcosine 1, isoleucine 8] angiotensin II, on blood pressure, plasma renin activity and plasma aldosterone concentration in hypertensive and normotensive subjects taking oral contraceptives.
    Endocrinologia japonica, 1979, Volume: 26, Issue:5

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Angiotensin II; Blood Pressure; Contrac

1979
[Biochemical diagnosis of hypertension in adrenal gland diseases].
    Polskie Archiwum Medycyny Wewnetrznej, 1979, Volume: 62, Issue:5

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Catecholamines; Corticosterone; Desoxycorticosterone; H

1979
Central and renal circulation, renin and aldosterone in plasma during prazosin treatment in essential hypertension.
    Acta medica Scandinavica, 1979, Volume: 206, Issue:6

    Topics: Adult; Aged; Aldosterone; Blood Chemical Analysis; Blood Circulation; Cardiac Output; Female; Hemody

1979
[Effects of minoxidil on blood pressure and plasma volume in refractory hypertension (author's transl)].
    La Nouvelle presse medicale, 1979, Oct-15, Volume: 8, Issue:39

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Dihydralazine; Female; Humans; Hypertension; Male; M

1979
Are idiopathic hyperaldosteronism and low-renin hypertension variants of essential hypertension?
    Annals of clinical biochemistry, 1979, Volume: 16, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Angiotensin II; Blood Pressure;

1979
Captopril in hypertension with renal artery stenosis and in intractable hypertension; acute and chronic changes in circulating concentrations of renin, angiotensins I and II and aldosterone, and in body composition.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Blood Pressure; Captopr

1979
Urinary kallikrein in normotensive subjects and in patients with essential hypertension.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Adult; Aldosterone; Creatinine; Furosemide; Humans; Hypertension; Kallikreins; Male; Potassium; Reni

1979
Sodium excretion and blood pressure in essential hypertensive patients during the early phase of hospital admission.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Cardiac Output; Female; Hospitalization; Human

1979
Haemodynamics during long-term thiazide treatment in essential hypertension: differences between responders and non-responders.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Adult; Aldosterone; Blood Pressure; Cardiac Output; Heart Rate; Humans; Hydrochlorothiazide; Hyperte

1979
The evidence that salt is an important aetiological agent, if not the cause, of hypertension.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoids; Renin; Risk; Sodium; Sodi

1979
Pathophysiological studies on hypertension induced in rats by kidney extract and salt.
    Japanese circulation journal, 1979, Volume: 43, Issue:12

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood

1979
The role of renal prostaglandin E and kallikrein in pathogenesis of essential hypertension.
    Japanese circulation journal, 1979, Volume: 43, Issue:12

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Femal

1979
[Effects of a single dose of captopril on blood pressure and the renin-angiotensin-aldosterone system in normal subjects and hypertensive patients with various etiologies (author's transl)].
    Nihon Jinzo Gakkai shi, 1979, Volume: 21, Issue:11

    Topics: Adult; Aldosterone; Angiotensin I; Angiotensins; Blood Pressure; Captopril; Humans; Hypertension; Ma

1979
The response of plasma renin activity by oral calcium loading in normal subjects and hypertensive and diabetic patients.
    Osaka city medical journal, 1979, Volume: 25, Issue:1

    Topics: Administration, Oral; Adult; Aldosterone; Angiotensin II; Calcium; Diabetes Complications; Diabetes

1979
Evaluation of patients for secondary hypertension.
    Transactions of the American Association of Genito-Urinary Surgeons, 1979, Volume: 71

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Cushing Syndrome; Female; Humans; Hyp

1979
[Reliability and diagnostic use of the furosemide test in the study of the renin-angiotensin-aldosterone system].
    Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:8

    Topics: Adolescent; Adult; Aldosterone; Cushing Syndrome; Electrolytes; Female; Furosemide; Humans; Hyperten

1978
[The renin-angiotensin-aldosterone system in arterial hypertension].
    Medicina, 1979, Volume: 39 Suppl 1

    Topics: Aldosterone; Angiotensins; Animals; Captopril; Dogs; Humans; Hypertension; Hypertension, Renovascula

1979
Is low urinary prostaglandin concentration a stage in the development of essential hypertension?
    Prostaglandins and medicine, 1979, Volume: 3, Issue:1

    Topics: Adult; Aldosterone; Humans; Hypertension; Kidney; Kidney Medulla; Middle Aged; Prostaglandins; Prost

1979
An association between the renin angiotensin system, blood pressure and potassium intake.
    Transactions of the American Clinical and Climatological Association, 1980, Volume: 91

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure; Humans; Hypertension; Potassium

1980
[Short-term effects of a treatment with methoprolol (a selective beta 1-blocking agent) in essential hypertension. Changes of haemodynamics, renin, aldosterone, sodium and potassium balance (author's transl)].
    Giornale italiano di cardiologia, 1979, Volume: 9, Issue:11

    Topics: Adult; Aldosterone; Drug Evaluation; Female; Hemodynamics; Humans; Hypertension; Male; Metoprolol; M

1979
[Temporal aspects of the function of the renin-angiotensin-aldosterone system. Contribution to the methodological standardization of explorative test (author's transl)].
    Annali dell'Istituto superiore di sanita, 1979, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Diet, Sodium-Restricted; Female; Furosemide; Human

1979
[Effect of potassium canrenoate on arterial pressure, plasma renin activity and urinary aldosterone in essential hypertension].
    Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Aldosterone; Canrenoic Acid; Female; Humans; Hypertension; Male; Middle Aged; Pre

1978
[Hemodynamic, humoral and renal effects of the acute administration of nifedipine in hypertensive patients].
    Bollettino della Societa italiana di cardiologia, 1979, Volume: 24, Issue:11

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Creatinine; Electrolytes; Female; Heart Ra

1979
Diurnal 18-hydroxy-11-deoxycorticosterone pattern in human stable hypertension.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:4

    Topics: 18-Hydroxydesoxycorticosterone; Adolescent; Adult; Aldosterone; Circadian Rhythm; Cushing Syndrome;

1978
Experimental toxemia of pregnancy in the monkey, with a preliminary report on renin and aldosterone.
    The American journal of pathology, 1977, Volume: 86, Issue:3

    Topics: Aldosterone; Animals; Aorta; Constriction; Disease Models, Animal; Female; Haplorhini; Hypertension;

1977
Value of the spironolactone test in the diagnosis of primary hyperaldosteronism.
    The Netherlands journal of medicine, 1979, Volume: 22, Issue:1

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potassium;

1979
Cardiovascular and endocrine profile of adrenergic neurone blockade in normal and hypertensive man.
    The American journal of medicine, 1979, Volume: 66, Issue:1

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Volume; Body Weight; Debrisoquin; Female; Hemodynami

1979
The biological significance of reduced metabolites of aldosterone.
    Human pathology, 1979, Volume: 10, Issue:2

    Topics: Aldosterone; Biotransformation; Humans; Hypertension; Renin

1979
Evidence for heterogeneity of mineralocorticoids in urine of patients with low renin essential hypertension.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 48, Issue:1

    Topics: Aldosterone; Corticosterone; Humans; Hypertension; Mineralocorticoids; Progesterone; Reference Value

1979
Role of the renin-angiotensin-aldosterone system in hypertensive children with coarctation of the aorta.
    The American journal of cardiology, 1979, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Angiotensins; Aortic Coarctation; Body Fluids; Cardiac Catheterizati

1979
Enhanced adrenal responsiveness to angiotensin II in patients with low renin essential hypertension.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 48, Issue:2

    Topics: Adolescent; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Dose-Response Relationship, Drug; Hu

1979
Effect of adrenal suppression with dexamethasone in essential hypertension.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 48, Issue:5

    Topics: Adrenal Glands; Adult; Aldosterone; Blood Pressure; Dexamethasone; Humans; Hydrocortisone; Hypertens

1979
Essential role of mean circulatory filling pressure in salt-induced hypertension.
    The American journal of physiology, 1979, Volume: 236, Issue:1

    Topics: Aldosterone; Animals; Blood Pressure; Blood Volume; Cardiac Output; Dogs; Heart Rate; Hydrocortisone

1979
Aldosterone, deoxycorticosterone, corticosterone, and prolactin changes during the lifespan of chronically and spontaneously hypertensive rats.
    Endocrinology, 1979, Volume: 104, Issue:5

    Topics: Aging; Aldosterone; Animals; Blood Pressure; Corticosterone; Desoxycorticosterone; Female; Hypertens

1979
Chronobiology of blood pressure.
    Nephron, 1979, Volume: 23, Issue:2-3

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Circadian Rhythm; Desoxycorticosterone;

1979
[Behavior of the renin-angiotensin-aldosterone system and of electrolyte and water excretion in male and female spontaneously hypertensive and normotensive rats under the influence of a saluretic].
    Zeitschrift fur Versuchstierkunde, 1979, Volume: 21, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Azoles; Circadian Rhythm; Corticosterone; Diuretics; Electroly

1979
Rapid blood pressure control with minoxidil: acute and chronic effects on blood pressure, sodium excretion, and the renin-aldosterone system.
    Archives of internal medicine, 1979, Volume: 139, Issue:5

    Topics: Adult; Aldosterone; Blood Pressure; Blood Volume; Creatinine; Diuretics; Heart Rate; Humans; Hyperte

1979
The metabolic clearance of aldosterone decreases similarly during infusion of angiotensin II in patients with essential hypertension and in normal subjects.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 49, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kinetics; Male; Metabolic Clearanc

1979
Age- and sex-related differences in plasma aldosterone in essential hypertension. Relationship to plasma renin activity.
    Klinische Wochenschrift, 1979, May-03, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Age Factors; Aldosterone; Female; Furosemide; Humans; Hydrocortisone; Hypertensio

1979
The adrenal cortex and arterial hypertension.
    Minerva medica, 1979, Jun-08, Volume: 70, Issue:27

    Topics: Adrenal Cortex Hormones; Aldosterone; Desoxycorticosterone; Extracellular Space; Humans; Hypertensio

1979
Effects of bromocryptine on hormone and blood pressure levels in the spontaneously hypertensive rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1979, Volume: 161, Issue:2

    Topics: Age Factors; Aldosterone; Animals; Blood Pressure; Body Weight; Bromocriptine; Corticosterone; Femal

1979
[Conn's disease with an edematous form of chronic glomerulonephritis].
    Terapevticheskii arkhiv, 1979, Volume: 51, Issue:5

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Chronic Disease; Edema; Female; Glomerulonephritis; Hum

1979
Effects of indomethacin on plasma renin activity, plasma aldosterone concentration, urinary prostaglandin E excretion and blood pressure in patients with essential hypertension.
    The Tohoku journal of experimental medicine, 1979, Volume: 128, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypertensio

1979
18-Hydroxy-11-deoxycorticosterone in hypertensive uremic patients during hemodialysis.
    Hormone research, 1979, Volume: 10, Issue:5

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Aged; Aldosterone; Desoxycorticosterone; Fe

1979
Aldosterone and its stimuli in normal and hypertensive man: are essential hypertension and primary hyperaldosteronism without tumour the same condition?
    The Journal of endocrinology, 1979, Volume: 81, Issue:2

    Topics: Adenoma; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hyperaldosteronism; Hyp

1979
Adrenocorticosteroids in experimental and human hypertension.
    The Journal of endocrinology, 1979, Volume: 81, Issue:2

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Animals; Biolo

1979
[Acute combined alpha- and beta-adrenergic blockade in essential hypertension: effects on blood pressure, renal function, renin, and aldosterone].
    Klinische Wochenschrift, 1979, Jul-15, Volume: 57, Issue:14

    Topics: Adult; Aldosterone; Blood Pressure; Diuresis; Drug Therapy, Combination; Female; Humans; Hypertensio

1979
Angiotensin II in primary hypertension, relationship to plasma renin activity, aldosterone and urinary electrolytes.
    Acta medica Scandinavica, 1979, Volume: 205, Issue:7

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Body Weight; Creatinine; Electrolytes; Female; Furosemide;

1979
Observations on edema formation in the nephrotic syndrome in adults with minimal lesions.
    The American journal of medicine, 1979, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Blood Volume; Creatinine; Edema; Female; Glomerular

1979
Idiopathic, sustained, inappropriate secretion of ADH with associated hypertension and thirst.
    The American journal of medicine, 1979, Volume: 67, Issue:3

    Topics: Adolescent; Aldosterone; Diet; Drinking; Female; Humans; Hypertension; Inappropriate ADH Syndrome; O

1979
Hypertension and aldosterone overproduction without renin suppression in Cushing's syndrome from an adrenal adenoma.
    The American journal of medicine, 1979, Volume: 67, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Corticosterone; Cushing Syndrome; Desoxycorti

1979
Effect of nifedipine on plasma renin, aldosterone and catecholamines in arterial hypertension.
    European journal of clinical pharmacology, 1979, May-21, Volume: 15, Issue:4

    Topics: Adult; Aged; Aldosterone; Catecholamines; Evaluation Studies as Topic; Female; Hemodynamics; Humans;

1979
[Hormonal contraceptives and high blood pressure (author's transl)].
    Medicina clinica, 1979, Jun-25, Volume: 73, Issue:2

    Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Contraceptives, Oral; Contraceptives, Oral, Hormonal; E

1979
Renin-aldosterone and vanillylmandelic acid in postpartum hypertension.
    Nephron, 1979, Volume: 23, Issue:5

    Topics: Aldosterone; Female; Humans; Hypertension; Posture; Pregnancy; Puerperal Disorders; Renin; Vanilmand

1979
Vascular responsiveness to pressor agents during human pregnancy.
    The Journal of reproductive medicine, 1979, Volume: 23, Issue:3

    Topics: Aldosterone; Angiotensin II; Aspirin; Female; Hematocrit; Humans; Hypertension; Indomethacin; Pregna

1979
The placenta and the renin-angiotensin system.
    The Journal of reproductive medicine, 1979, Volume: 23, Issue:3

    Topics: Aldosterone; Angiotensin II; Female; Fetus; Humans; Hypertension; Maternal-Fetal Exchange; Placenta;

1979
Postural effects on renal function and volume homeostasis during pregnancy.
    The Journal of reproductive medicine, 1979, Volume: 23, Issue:3

    Topics: Adult; Aldosterone; Female; Glomerular Filtration Rate; Homeostasis; Humans; Hydrocortisone; Hyperte

1979
[Salt restriction test].
    Nihon rinsho. Japanese journal of clinical medicine, 1979, Jun-29, Volume: Suppl

    Topics: Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Renin

1979
[DOCA loading test].
    Nihon rinsho. Japanese journal of clinical medicine, 1979, Jun-29, Volume: Suppl

    Topics: Aldosterone; Desoxycorticosterone; Humans; Hyperaldosteronism; Hypertension

1979
[Role of steroid hormones in the etiology and clinical course of hypertension].
    Kardiologiia, 1979, Volume: 19, Issue:8

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Female; Humans; Hydrocortisone; Hypertension; Male;

1979
Genetic aspects of plasma aldosterone binding globulins in families of patients with essential hypertension, including isolation of novel thermostable homologues from plasma and urine.
    Journal of steroid biochemistry, 1979, Volume: 11, Issue:1C

    Topics: Adolescent; Adult; Aged; Aldosterone; Canrenoic Acid; Carrier Proteins; Child; Child, Preschool; Fem

1979
Adrenal sensitivity to angiotensin II and undiscovered aldosterone stimulating factors in hypertension.
    Journal of steroid biochemistry, 1979, Volume: 11, Issue:1C

    Topics: Adrenal Glands; Adult; Aldosterone; Dexamethasone; Female; Humans; Hyperaldosteronism; Hypertension;

1979
[A nephrologist's thoughts on pregnancy toxemia].
    Minerva medica, 1979, Oct-06, Volume: 70, Issue:43

    Topics: Aldosterone; Angiotensins; Edema; Female; Glomerular Filtration Rate; Glomerulonephritis; Humans; Hy

1979
Volume studies in men with mild to moderate hypertension.
    The American journal of cardiology, 1979, Volume: 44, Issue:6

    Topics: Adult; Aldosterone; Body Fluids; Body Water; Erythrocyte Volume; Extracellular Space; Heart Rate; Hu

1979
Effect of prostaglandin E1 on renin and aldosterone in hypertensive patients.
    Endocrinologia japonica, 1979, Volume: 26, Issue:4

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Indomethacin; Male; Middle Aged; Propranolol; Pros

1979
Abnormal adrenal responsiveness and angiotensin II dependency in high renin essential hypertension.
    The Journal of clinical investigation, 1979, Volume: 64, Issue:5

    Topics: Adrenal Cortex; Adrenal Cortex Function Tests; Adult; Aldosterone; Angiotensin II; Blood Pressure; D

1979
Effects of sodium loading and depletion in normotensive first-degree relatives of essential hypertensives.
    The Journal of laboratory and clinical medicine, 1979, Volume: 94, Issue:5

    Topics: Adult; Aldosterone; Creatinine; Female; Furosemide; Humans; Hypertension; Kidney; Kidney Function Te

1979
Decreased hepatic delta 4-reductase activity for aldosterone in SHR [proceedings].
    Japanese heart journal, 1979, Volume: 20, Issue:5

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aldosterone; Animals; Hypertension; Liver; Oxidoreductases; R

1979
[Renin activity and the aldosterone and cortisol content in the blood depending on the course of hypertension].
    Klinicheskaia meditsina, 1979, Volume: 57, Issue:10

    Topics: Adult; Aldosterone; Blood Pressure; Chronic Disease; Coronary Disease; Enzyme Activation; Humans; Hy

1979
Ticrynafen: a new thiazide-like but uricosuric antihypertensive diuretic.
    The New England journal of medicine, 1979, 12-20, Volume: 301, Issue:25

    Topics: Aldosterone; Animals; Glomerular Filtration Rate; Glycolates; Hemodynamics; Humans; Hypertension; Ki

1979
Hypertension and hyperkalaemia responding to bendrofluazide.
    The Quarterly journal of medicine, 1979, Volume: 48, Issue:190

    Topics: Adult; Aldosterone; Arginine Vasopressin; Bendroflumethiazide; Diet, Sodium-Restricted; Furosemide;

1979
Blood pressure reduction by incremental infusion of labetalol in patients with severe hypertension.
    British journal of clinical pharmacology, 1979, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Ethanolamines; Female; Heart R

1979
Minoxidil increases aldosterone metabolic clearance in hypertensive patients.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 49, Issue:6

    Topics: Adult; Aldosterone; Humans; Hypertension; Kidney Failure, Chronic; Metabolic Clearance Rate; Middle

1979
[Nature of the reaction of blood plasma steroid hormones in hypertension to various types of stimulation].
    Kardiologiia, 1979, Volume: 19, Issue:12

    Topics: Adolescent; Adult; Aldosterone; Furosemide; Humans; Hydrocortisone; Hypertension; Male; Middle Aged;

1979
Vaule of renin measurement, saralasin test, and acebutolol treatment in hypertension.
    Kidney international, 1979, Volume: 15, Issue:2

    Topics: Acebutolol; Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet; Heart Rate; Humans

1979
Aldosterone 18-glucuronide excretion determined with and without chromatography in human hypertensives.
    Klinische Wochenschrift, 1979, Oct-15, Volume: 57, Issue:20

    Topics: Aldosterone; Chromatography, Paper; Circadian Rhythm; Glucuronates; Humans; Hypertension; Radioimmun

1979
Renal kallikrein-kinin system and prostaglandin in hypertension: their relation to renin-angiotensin-aldosterone system.
    Advances in experimental medicine and biology, 1979, Volume: 120B

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensins; Diet, Sodium-Restricted; Female; Furosemide; Hum

1979
Defect in kallikrein-kinin-system in essential hypertension and reduction of blood pressure by orally given kallikrein.
    Advances in experimental medicine and biology, 1979, Volume: 120B

    Topics: Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Kallikreins; Refe

1979
Dissociation in the excretion of different aldosterone metabolites and unmetabolized ('free') aldosterone in hypertension.
    Clinical science (London, England : 1979), 1979, Volume: 57, Issue:5

    Topics: 18-Hydroxycorticosterone; Aldosterone; Glucuronates; Humans; Hyperaldosteronism; Hypertension; Renal

1979
Studies on the renin-angiotensin-aldosterone system in elderly hypertensive patients with an angiotensin II antagonist.
    Clinical science (London, England : 1979), 1979, Volume: 57, Issue:5

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; F

1979
Effect of oral labetalol on plasma catecholamines, renin and aldosterone in patients with severe arterial hypertension.
    European journal of clinical pharmacology, 1979, Volume: 16, Issue:5

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Catecholamines; Epinephrine; Ethanolamines; F

1979
Haemodynamic effects of treatment and withdrawal of spironolactone in essential hypertension.
    Scandinavian journal of clinical and laboratory investigation, 1979, Volume: 39, Issue:2

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Body Weight; Cardiac Output; Creatini

1979
Effect of triamterene on urinary excretion of immunoreactive prostaglandin E in essential hypertension.
    The Tohoku journal of experimental medicine, 1979, Volume: 129, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Angiotensins; Blood Pressure; Female; Humans; Hypertension; Kidney;

1979
[Sodium chloride and hypertension (an additional, temporary hypothesis)].
    Zeitschrift fur Ernahrungswissenschaft, 1979, Volume: 18, Issue:2

    Topics: Aldosterone; Angiotensins; Animals; Body Weight; Diet, Sodium-Restricted; Disease Models, Animal; Hu

1979
The renin-angiotensin-aldosterone system in hypertension: its biochemistry and applications.
    Acta clinica Belgica, 1979, Volume: 34, Issue:4

    Topics: Adult; Age Factors; Aldosterone; Amino Acid Sequence; Angiotensin II; Angiotensins; Female; Humans;

1979
[Effect of hypotensive therapy depending on the blood level of steroid hormones and their reaction to diuretics].
    Terapevticheskii arkhiv, 1979, Volume: 51, Issue:12

    Topics: Adolescent; Adult; Aldosterone; Furosemide; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension

1979
[Clinical and experimental studies of plasma and urinary aldosterone determination].
    Horumon to rinsho. Clinical endocrinology, 1977, Volume: 25, Issue:2

    Topics: Adult; Aged; Aldosterone; Evaluation Studies as Topic; Female; Humans; Hyperaldosteronism; Hypertens

1977
[Low renin hypertension and aldosterone].
    Horumon to rinsho. Clinical endocrinology, 1977, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Ren

1977
[Simple determination of plasma aldosterone with aldosterone radioimmunoassay kit using 125I-aldosterone].
    Horumon to rinsho. Clinical endocrinology, 1977, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Iodine Radioisotopes; Male; Middle Age

1977
[Effect of carbon baths on blood pressure level of aldosterone, renin, minerals in the blood and catecholamines in the urine of patients with essential hypertension].
    Fysiatricky a reumatologicky vestnik, 1977, Volume: 55, Issue:4

    Topics: Adult; Aldosterone; Balneology; Blood Pressure; Carbon; Catecholamines; Female; Humans; Hypertension

1977
Diagnosis of secondary forms of hypertension. A comprehensive protocol.
    JAMA, 1977, Mar-28, Volume: 237, Issue:13

    Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Female; Furosemide; Humans; Hy

1977
Radioimmunoassays of tetrahydroaldosterone (TH-aldo) in human urine.
    Acta endocrinologica, 1978, Volume: 87, Issue:3

    Topics: Aldosterone; Antigens; Cross Reactions; Glucuronates; Humans; Hyperaldosteronism; Hypertension; Immu

1978
Effect of an angiotensin II analogue upon blood pressure, plasma renin concentration and plasma aldosterone in hypertensive patients.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:8

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male;

1979
The application of neurologic reflexes to the treatment of hypertension.
    The Journal of the American Osteopathic Association, 1979, Volume: 79, Issue:4

    Topics: Adult; Aldosterone; Humans; Hypertension; Male; Middle Aged; Osteopathic Medicine; Reflex; Renin

1979
The renin-aldosterone system in exaggerated natriuresis of essential hypertension.
    Clinical science and molecular medicine, 1977, Volume: 53, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Natriuresis; Renin; Sodium;

1977
[Pathophysiology of hypertension (author's transl)].
    Rinsho byori. The Japanese journal of clinical pathology, 1977, Volume: 25, Issue:10

    Topics: Aldosterone; Angiotensin II; Diagnosis, Differential; Humans; Hypertension; Renin

1977
[Various humoral pressor and depressor systems in hypertension].
    Kardiologiia, 1977, Volume: 17, Issue:10

    Topics: Adolescent; Adult; Aldosterone; Catecholamines; Diuresis; Humans; Hydrocortisone; Hypertension; Kall

1977
[Plasma aldosterone concentration and vascular reactivity in hypertension].
    Kardiologiia, 1977, Volume: 17, Issue:10

    Topics: Adult; Aldosterone; Angiotensin II; Blood Vessels; Humans; Hypertension; Male; Middle Aged; Norepine

1977
Effects of 1-Sar-8-Ile-angiotensin II on urinary prostaglandin excretion in patients with essential hypertension.
    The Tohoku journal of experimental medicine, 1977, Volume: 123, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Female; Humans; Hypertensio

1977
[Hyperkalemic, hyperchloremic acidosis in moderate chronic renal insufficiency and selective hypoaldosteronism].
    L'union medicale du Canada, 1977, Volume: 106, Issue:12

    Topics: Acidosis; Adult; Aged; Aldosterone; Chlorides; Female; Humans; Hyperkalemia; Hypertension; Kidney Fa

1977
[The adrenergic system and the control of the renin and aldosterone circadian rhythm in essential arterial hypertension].
    Bollettino della Societa italiana di biologia sperimentale, 1977, Oct-30, Volume: 53, Issue:20

    Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Female; Humans; Hydrocortisone; Hypertension; Male

1977
[Circadian rhythm of renin and aldosterone in essential arterial hypertension].
    Bollettino della Societa italiana di biologia sperimentale, 1977, Oct-30, Volume: 53, Issue:20

    Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Humans; Hydrocortisone; Hypertension; Renin

1977
Influence of pentobarbitalnatrium (Nembutal) narcosis on blood pressure, plasma renin activity, aldosterone, sodium and potassium in normotensive and spontaneously hypertensive rats.
    Comptes rendus de l'Academie Bulgare des sciences : sciences mathematiques et naturelles, 1977, Volume: 30, Issue:11

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Hypertension; Pentobarbital; Potassium; Rats; Rat

1977
[Liddle's syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 1977,Spring, Volume: 35 Suppl 1

    Topics: Aldosterone; Alkalosis; Humans; Hypertension; Hypokalemia; Renin; Syndrome

1977
[Modification of genetic hypertension in rats].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone; Denervation; Diet, Sodium-Rest

1977
[What role does the renin-angiotensin system have in the pathogenesis of hypertension?].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Aldosterone; Angiotensin II; Animals; Corticosterone; Desoxycorticosterone; Extracellular Space; Hyp

1977
[Relationship between plasma noradrenaline (PNA), plasma renin activity (PRA), plasma aldosterone (PAC) and sodium excretion (U-Na+) in primary hypertension].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Aldosterone; Humans; Hypertension; Norepinephrine; Renin; Sodium

1977
[Diagnostic ability of the renin-angiotensin-aldosterone-system (R.A.A.-system) stimulation as a screening test in hypertension].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Aldosterone; Angiotensin II; Diagnosis, Differential; Furosemide; Humans; Hypertension; Hypertension

1977
[Hemodynamics, renin and aldosterone following angiotensin II blockade and sodium chloride deficiency in hypertensive subjects].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Diet, Sodium-Restricted; Heart Rate; He

1977
[Kidney function in essential hypertension].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Aldosterone; Blood Pressure; Diuresis; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Nat

1977
[Correlations between plasma volume, hemodynamic indices and hematochemical parameters in hypertensive patients (proceedings)].
    Bollettino della Societa italiana di cardiologia, 1977, Volume: 22, Issue:8

    Topics: Aldosterone; Hemodynamics; Humans; Hypertension; Plasma Volume; Renin

1977
The role of adrenal mineralocorticoids in hypertension.
    Geriatrics, 1978, Volume: 33, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hyperplas

1978
Aldosterone in the exaggerated natriuresis of spontaneously hypertensive rats.
    The American journal of physiology, 1978, Volume: 234, Issue:1

    Topics: Aldosterone; Animals; Body Water; Diet; Extracellular Space; Hypertension; Kidney; Male; Natriuresis

1978
The integrated concentration of plasma renin activity and aldosterone in essential hypertension.
    The Johns Hopkins medical journal, 1978, Volume: 142, Issue:2

    Topics: Adult; Aged; Aldosterone; Furosemide; Humans; Hypertension; Male; Middle Aged; Renin

1978
[Oral contraceptives, hypertension and nephrosclerosis].
    Fortschritte der Medizin, 1978, Feb-16, Volume: 96, Issue:7

    Topics: Adult; Aldosterone; Animals; Blood Coagulation; Contraceptives, Oral; Estrogens; Female; Humans; Hyp

1978
Effect of saralasin on plasma aldosterone in hypertensive man.
    The Journal of laboratory and clinical medicine, 1978, Volume: 91, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Furosemide; Humans; Hypertension; Hypert

1978
The possible importance of aldosterone as well as renin in the long-term antihypertensive action of propranolol.
    The American journal of medicine, 1978, Volume: 64, Issue:2

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Depression, Chemical; Female; Humans; Hypertension; Male;

1978
The effect of high-sodium and low-sodium intakes on blood pressure and other related variables in human subjects with idiopathic hypertension.
    The American journal of medicine, 1978, Volume: 64, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Blood Volume; Body Weight; Diet; Humans; Hypertension; Middle Ag

1978
Effect of furosemide on urinary kallikrein excretion in patients with essential hypertension.
    The Tohoku journal of experimental medicine, 1978, Volume: 124, Issue:3

    Topics: Adult; Aldosterone; Female; Furosemide; Humans; Hypertension; Kallikreins; Male; Middle Aged; Potass

1978
The multiple factors affecting plasma renin activity in essential hypertension.
    Archives of internal medicine, 1978, Volume: 138, Issue:4

    Topics: Adolescent; Adult; Aged; Aldosterone; Dopamine beta-Hydroxylase; Epinephrine; Female; Furosemide; Hu

1978
Familial hyperkalemia, hypertension, and hyporeninemia with normal aldosterone levels. A tubular defect in potassium handling.
    Archives of internal medicine, 1978, Volume: 138, Issue:4

    Topics: Acidosis; Adrenal Glands; Aldosterone; Humans; Hyperkalemia; Hypertension; Kidney; Male; Middle Aged

1978
The effect of an angiotensin antagonist (saralasin) on arterial pressure and plasma aldosterone in hemodialysis-resistant hypertensive patients.
    Clinical nephrology, 1978, Volume: 9, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Filtration; Humans; Hypertension; Male;

1978
Use of the angiotensin I antagonist, SQ 20881, for lateralizing renal venous renin activity.
    Israel journal of medical sciences, 1978, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensins; Blood; Blood Pressure; Humans; Hyperten

1978
Changes in renal function in essential hypertension.
    The American journal of medicine, 1978, Volume: 64, Issue:4

    Topics: Aldosterone; Blood Pressure; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney;

1978
Comparison of the antihypertensive and hormonal effects of a cardioselective beta-blocker, acebutolol, and diuretics in essential hypertension.
    The American journal of medicine, 1978, Volume: 64, Issue:6

    Topics: Acebutolol; Adult; Aldosterone; Amiloride; Blood Pressure; Dose-Response Relationship, Drug; Drug Th

1978
Relative significance of plasma renin activity and concentration in physiologic and pathophysiologic conditions.
    Angiology, 1978, Volume: 29, Issue:5

    Topics: Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Diet; Diet, Sodium-Restricted; Female; Humans

1978
The pressor response to angiotensin II in patients with low renin essential hypertension.
    Circulation research, 1978, Volume: 42, Issue:6

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Urea Nitrogen; Humans; Hyperaldosteronism;

1978
[Biochemical profile of essential arterial hypertension. Indications for a targeted therapy: experience with propranolol].
    La Clinica terapeutica, 1978, Apr-15, Volume: 85, Issue:1

    Topics: Aldosterone; Drug Evaluation; Humans; Hypertension; Propranolol; Renin

1978
Aldosterone responsiveness in patients with diabetes mellitus.
    Diabetes, 1978, Volume: 27, Issue:7

    Topics: Aldosterone; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Electrolytes; Female

1978
Increased adrenal sensitivity to angiotensin II in low-renin essential hypertension.
    The Journal of clinical investigation, 1978, Volume: 61, Issue:6

    Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Female; Furosemide; Humans; Hypertension; Male;

1978
Plasma renin activity, aldosterone and sodium excretion in women with high and low casual blood pressure levels.
    Acta medica Scandinavica, 1978, Volume: 203, Issue:5

    Topics: Adolescent; Aged; Aldosterone; Blood Pressure Determination; Female; Humans; Hypertension; Middle Ag

1978
An approach to mineralocorticoid hormone hypertension.
    Cardiovascular clinics, 1978, Volume: 9, Issue:1

    Topics: Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Aldosterone; Cushing Syndrome; Desoxy

1978
Adrenal steroidogenesis and hepatic corticosteroid metabolism in hypertensive rats.
    Endocrinologia japonica, 1978, Volume: 25, Issue:2

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Animals

1978
[Studies on kallikrein-kinin system in essential hypertension: urinary kallikrein-kinin system and renin-angiotensin-aldosterone system (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1978, May-10, Volume: 67, Issue:5

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Kallikreins; Kinins; Male; Middle Aged; Renin

1978
Comparison of the biological effects of two angiotensin II analogues in hypertensive patients with sodium depletion.
    Life sciences, 1978, Jun-05, Volume: 22, Issue:21

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Renin; S

1978
[The renin-angiotensin-aldosterone system and hypertensive syndromes].
    La Revue du praticien, 1978, May-21, Volume: 28, Issue:29

    Topics: Aldosterone; Angiotensins; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Renin

1978
[Role of aldosterone in the pathogenesis of spontaneous (hereditarily determined) hypertension in rats].
    Vestnik Akademii meditsinskikh nauk SSSR, 1978, Issue:7

    Topics: Age Factors; Aldosterone; Animals; Body Weight; Hypertension; Rats; Rats, Inbred Strains

1978
[The urologist and hypertension].
    Acta urologica Belgica, 1978, Volume: 46, Issue:2

    Topics: Acute Disease; Aldosterone; Angiotensins; Central Nervous System; Child; Humans; Hypertension; Hyper

1978
Failure of chronic aldosterone infusion to increase arterial pressure in dogs with angiotensin-induced hypertension.
    Circulation research, 1978, Volume: 43, Issue:3

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Computers; Dogs; Hematocrit; Hy

1978
Subpressor angiotensin infusion, renal sodium handling, and salt-induced hypertension in the dog.
    Circulation research, 1978, Volume: 43, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Furose

1978
[The effect of cortisol infusion on plasma renin activity, aldosterone levels and 11-deoxycorticosterone levels in humans (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1978, May-20, Volume: 54, Issue:5

    Topics: Adolescent; Adult; Aldosterone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hyperaldostero

1978
Influence of sodium intake on hydrochlorothiazide-induced changes in blood pressure, serum electrolytes, renin and aldosterone in essential hypertension.
    Acta medica Scandinavica, 1978, Volume: 204, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Humans; Hydrochlorothiazid

1978
Effects of 1-sar-8-ala-angiotensin II on arterial pressure, renin and aldosterone in hypertension.
    Contributions to nephrology, 1978, Volume: 11

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet; Female; Humans; Hypertension; Male; Renin;

1978
Antihypertensive effect of volume depletion: interrelation with renal prostaglandins.
    Contributions to nephrology, 1978, Volume: 12

    Topics: Aldosterone; Animals; Blood Pressure; Furosemide; Humans; Hypertension; Indomethacin; Kidney; Kidney

1978
Implication of renal prostaglandin E in urinary sodium excretion.
    Japanese circulation journal, 1978, Volume: 42, Issue:5

    Topics: Adolescent; Adult; Aged; Aldosterone; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Prost

1978
Aldosterone in primary hypertension relationship to plasma renin activity and urinary electrolytes and a comparison with normotensive subjects.
    Scandinavian journal of clinical and laboratory investigation, 1978, Volume: 38, Issue:5

    Topics: Adult; Aged; Aging; Aldosterone; Blood Pressure; Electrolytes; Female; Humans; Hypertension; Male; M

1978
[Individual renal blood flow and activity of the renin-aldosterone system in patients with renovascular hypertension and hypertensive disease].
    Vestnik Akademii meditsinskikh nauk SSSR, 1978, Issue:10

    Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Renin

1978
Role of renin and aldosterone suppression in the antihypertensive mechanism of clonidine.
    The American journal of medicine, 1978, Volume: 65, Issue:4

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Clonidine; Female

1978
Use of diuretics in treatment of hypertension secondary to renal disease.
    Archives of internal medicine, 1978, Volume: 138, Issue:10

    Topics: Adult; Aldosterone; Antihypertensive Agents; Creatinine; Female; Furosemide; Humans; Hydrochlorothia

1978
Hypertension and oral contraceptives.
    British medical journal, 1978, Oct-21, Volume: 2, Issue:6145

    Topics: Aldosterone; Contraceptives, Oral; Female; Humans; Hypertension; Mineralocorticoids; Renin

1978
Role of aldosterone in the antihypertensive effect of spironolactone in essential hypertension.
    Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Electrolytes; Female; Humans; Hypertension; Kidney;

1978
[Saralasin for renovascular or essential hypertension (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1978, Nov-10, Volume: 103, Issue:45

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Hypert

1978
Plasma mineralocorticoids, plasma renin, and urinary kallikrein in salt-sensitive and salt-resistant rats.
    Endocrine research communications, 1978, Volume: 5, Issue:1

    Topics: 18-Hydroxydesoxycorticosterone; Aldosterone; Animals; Blood Pressure; Body Weight; Corticosterone; D

1978
[Studies of urinary kallikrein in patients with various types of hypertension (relationship to renin-angiotension-aldosterone system (author's transl)].
    Nihon Jinzo Gakkai shi, 1978, Volume: 20, Issue:8

    Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kallikreins; Kidney Diseases; Male

1978
[Study on etiology of hypertension in patients on chronic hemodialysis (author's transl)].
    Nihon Jinzo Gakkai shi, 1978, Volume: 20, Issue:8

    Topics: Adult; Aldosterone; Dopamine beta-Hydroxylase; Humans; Hypertension; Middle Aged; Renal Dialysis; Re

1978
[Saralasin-induced changes of blood pressure, renin and aldosterone in essential and renal hypertension (author's transl)].
    Klinische Wochenschrift, 1978, Sep-01, Volume: 56, Issue:17

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Hypertension, Renal; Renin; Saral

1978
[New differential diagnostic and therapeutic possibilities in arterial hypertension].
    Klinicheskaia meditsina, 1978, Volume: 56, Issue:10

    Topics: Adult; Aldosterone; Antihypertensive Agents; Diagnosis, Differential; Humans; Hypertension; Hyperten

1978
[Long-term minoxidil therapy: renin, aldosterone, noradrenaline and the need for beta blockers].
    Schweizerische medizinische Wochenschrift, 1978, Nov-04, Volume: 108, Issue:44

    Topics: Adult; Aldosterone; Chlorthalidone; Female; Furosemide; Hirsutism; Humans; Hypertension; Male; Middl

1978
Blood pressure, renin-angiotensin system and urinary kallikrein in a case of juxtaglomerular cell tumor.
    The American journal of medicine, 1978, Volume: 65, Issue:3

    Topics: Acebutolol; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Half-Life; Humans; Hypertens

1978
Familial hyperpotassemia and hypertension accompanied by normal plasma aldosterone levels: possible hereditary cell membrane defect.
    Archives of internal medicine, 1978, Volume: 138, Issue:12

    Topics: Adult; Aldosterone; Cell Membrane; Humans; Hyperkalemia; Hypertension; Insulin; Kidney Function Test

1978
Proximal renal tubular acidosis: association with familial normaldosteronemic hyperpotassemia and hypertension.
    Archives of internal medicine, 1978, Volume: 138, Issue:12

    Topics: Acidosis, Renal Tubular; Adult; Aldosterone; Child; Child, Preschool; Female; Humans; Hyperkalemia;

1978
[Renin-angiotensin-aldosterone system and electrolytes metabolism on furosemide stimulation test (author's transl)].
    Nihon Jinzo Gakkai shi, 1978, Volume: 20, Issue:7

    Topics: Aldosterone; Diet, Sodium-Restricted; Electrolytes; Furosemide; Humans; Hypertension; Renin

1978
Studies on hypertension: changes of humoral factors under long-term administration of thiazide.
    Japanese heart journal, 1978, Volume: 19, Issue:4

    Topics: Aldosterone; Animals; Benzothiadiazines; Catecholamines; Diuretics; Hypertension; Rats; Renin; Sodiu

1978
[Responses of renin-angiotensin-aldosterone system to insulin hypoglycemia in patients with essential hypertension (author's transl)].
    Nihon Jinzo Gakkai shi, 1978, Volume: 20, Issue:10

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypoglycemia; Insulin; Male;

1978
Aldosterone diagnosis in hypertension: comparative evaluation of radioimmunoassays for urinary aldosterone and 18-OH-corticosterone.
    Klinische Wochenschrift, 1978, Volume: 56 Suppl 1

    Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Aldosterone; Chromatography; Corticosteron

1978
Blood pressure responses to extremes of sodium intake in normal man.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 159, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Body Weight; Diet; Diuresis; Humans; Hypertension; Kidney; Male;

1978
The effect of the converting enzyme inhibitor SQ 20.881 on kinins, renin-angiotensin-aldosterone and catecholamines in relation to blood pressure in hypertensive patients.
    Acta medica Scandinavica, 1978, Volume: 204, Issue:6

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Catecholamines; Epinephrine; Female; Humans; Hyp

1978
Effects of furosemide on plasma renin and aldosterone in three subtypes of essential hypertension.
    Bollettino della Societa italiana di biologia sperimentale, 1978, Jan-30, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Renin;

1978
Kinetic variations of plasma renin and aldosterone during active orthostatism in three subtypes of essential hypertension.
    Bollettino della Societa italiana di biologia sperimentale, 1978, Jan-30, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Posture;

1978
[Effect of oral sodium load on the renin and aldosterone secretion in essential hypertension. Comparison to normal persons].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84

    Topics: Aldosterone; Hypertension; Renin; Sodium

1978
[Total body potassium in low renin essential hypertension with reference to the renin-angiotensin-aldosterone system (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1978, Dec-10, Volume: 67, Issue:12

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kidney; Male; Middle Aged; P

1978
[Studies on renal prostaglandin E in essential hypertension: relationships among urinary prostaglandin E, sodium balance, renin-angiotensin-aldosterone system and renal kallikrein-kinin system (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1978, Dec-10, Volume: 67, Issue:12

    Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kallikreins; Kidney; Male; Prostag

1978
[Plasma prostaglandins and the renin-aldosterone system in patients with labile or permanent essential hypertension].
    Journal d'urologie et de nephrologie, 1978, Volume: 84, Issue:12

    Topics: Adult; Aldosterone; Electrolytes; Humans; Hypertension; Kidney; Plasma Volume; Prostaglandins E; Pro

1978
[Mechanism of sodium retention in nephrotic syndrome: role of aldosterone and glomerular filtration].
    Journal d'urologie et de nephrologie, 1978, Volume: 84, Issue:9

    Topics: Aldosterone; Glomerular Filtration Rate; Humans; Hypertension; Kidney Glomerulus; Natriuresis; Nephr

1978
Age versus urinary sodium for judging renin, aldosterone, and catecholamine levels: studies in normal subjects and patients with essential hypertension.
    Kidney international, 1978, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aldosterone; Catecholamines; Epinephrine; Female; Humans; Hype

1978
The characterization of low renin hypertension by plasma renin activity and plasma aldosterone concentration.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:2

    Topics: Adult; Aged; Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Mathematics; Middle Aged; R

1978
Sodium metabolism in essential hypertension. Natriuretic response to acute hypertonic saline load.
    Japanese heart journal, 1978, Volume: 19, Issue:6

    Topics: Aldosterone; Blood Pressure; Blood Proteins; Humans; Hydrocortisone; Hypertension; Kidney Tubules; N

1978
Evidence for an angiotensinogenic mechanism of the hypertension of Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure;

1978
Interrelations between plasma renin activity, aldosterone, and sympathetic nervous system activity in essential hypertension.
    Acta biologica et medica Germanica, 1978, Volume: 37, Issue:10

    Topics: Adolescent; Adult; Aldosterone; Dopamine beta-Hydroxylase; Female; Humans; Hydrocortisone; Hypertens

1978
Relationship of basal plasma norepinephrine to blood pressure, plasma renin activity, mineralocorticoids, and plasma volume in essential hypertension.
    Transactions of the Association of American Physicians, 1978, Volume: 91

    Topics: 18-Hydroxydesoxycorticosterone; Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Ma

1978
[Effect of guanabenz on arterial pressure and the renin-aldosterone system in hypertensive patients].
    Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:1

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Guanabenz; Guanidines; Heart Rate; Humans; Hypertension; H

1978
The effect of indomethacin on plasma renin activity and urinary aldosterone of patients with essential hypertension.
    Journal of endocrinological investigation, 1978, Volume: 1, Issue:4

    Topics: 17-Ketosteroids; Adult; Aldosterone; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Hype

1978
Renin-angiotensin-aldosterone system in long-term renal transplant patients.
    Urology, 1976, Volume: 7, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Animals; Diet, Sodium-Restricted; Dogs; Follow-Up Studies; Human

1976
Plasma renin activity (PRA) and plasma aldosterone (PA) in hypertensive kidney allograft recipients.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1976, Volume: 12

    Topics: Aldosterone; Humans; Hypertension; Kidney Transplantation; Postoperative Complications; Renin; Sodiu

1976
Plasma renin, plasma aldosterone, exchangeable sodium and renal hemodynamics in normotensive and hypertensive recipients of a kidney transplant with and without transplant renal artery stenosis.
    Acta medica Scandinavica. Supplementum, 1976, Volume: 602

    Topics: Aldosterone; Blood Pressure; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal;

1976
[Equilibration of the treatment of severe arterial hypertension. Significance of d-1 propranolol].
    La Nouvelle presse medicale, 1975, Jan-04, Volume: 4, Issue:1

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Heart Rate; Humans; Hydralazine; Hypertension; Long-Ter

1975
Renin-angiotensin-aldosterone system in diabetes mellitus.
    Diabetes, 1976, Volume: 25, Issue:2 SUPPL

    Topics: Aldosterone; Angiotensin II; Animals; Blood Volume; Diabetes Mellitus; Diabetes Mellitus, Experiment

1976
Study of aldosterone levels in plasma during pregnancy.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:1

    Topics: Aldosterone; Female; Humans; Hypertension; Menstruation; Methods; Parity; Pregnancy; Pregnancy Compl

1977
[Importance of the simultaneous estimation of aldosterone, 18-hydroxy-11-deoxycorticosterone and cortisol in the adrenal veins in arterial hypertension with suppressed renin (author's transl)].
    Sbornik lekarsky, 1977, Volume: 79, Issue:1

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Glands; Aldosterone; Desoxycorticosterone; Humans; Hydrocort

1977
Renin reactivity as a determinant of responsiveness to antihypertensive treatment.
    Archives of internal medicine, 1977, Volume: 137, Issue:3

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Body Weight; Chlorthalidone; Drug

1977
[Effect of dietary salt restriction and erect posture on plasma renin activity and aldosteronemia in patients with essential hypertension].
    Polskie Archiwum Medycyny Wewnetrznej, 1977, Volume: 57, Issue:2

    Topics: Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Posture; Renin

1977
Natriuretic response to saline infusion in normotensive and hypertensive man. The role of renin suppression in exaggerated natriuresis.
    Circulation, 1977, Volume: 55, Issue:5

    Topics: Adolescent; Adult; Aged; Aldosterone; Female; Furosemide; Humans; Hyperaldosteronism; Hypertension;

1977
An abnormality in steroid reductive metabolism in a hypertensive syndrome.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:4

    Topics: Aldosterone; Cortisone; Glucocorticoids; Humans; Hydrocortisone; Hypertension

1977
Influence of thiazide on salt hypertension.
    Circulation research, 1977, Volume: 40, Issue:5 Suppl 1

    Topics: Aldosterone; Animals; Blood Pressure; Chlorothiazide; Hypertension; Male; Natriuresis; Rats; Renin;

1977
Isolation of a hypertension-producing compound from normal human urine.
    Circulation research, 1977, Volume: 40, Issue:5 Suppl 1

    Topics: Aldosterone; Animals; Blood Pressure; Blood Volume; Heart Rate; Humans; Hypertension; Kidney; Molecu

1977
[Metoprolol in essential arterial hypertension].
    L'union medicale du Canada, 1977, Volume: 106, Issue:4

    Topics: Adult; Aldosterone; Diet; Drug Evaluation; Female; Humans; Hypertension; Male; Metoprolol; Middle Ag

1977
Alloxan diabetes in spontaneously hypertensive rats: gravimetric, metabolic and histopathological alterations.
    British journal of experimental pathology, 1977, Volume: 58, Issue:2

    Topics: Aldosterone; Animals; Body Weight; Cardiovascular Diseases; Corticosterone; Diabetes Mellitus, Exper

1977
Prostaglandins and the renal antihypertensive function.
    Comprehensive therapy, 1977, Volume: 3, Issue:5

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Furosemide; Humans; Hypertension; Ind

1977
Evaluation of patients for secondary hypertension.
    Comprehensive therapy, 1977, Volume: 3, Issue:5

    Topics: Adolescent; Adult; Aged; Aldosterone; Female; Hospitalization; Humans; Hyperaldosteronism; Hypertens

1977
[Aldosteronemia and plasma renin activity in patients with hypertension treated with visken (prindolol)].
    Kardiologia polska, 1977, Volume: 20, Issue:2

    Topics: Aldosterone; Humans; Hypertension; Pindolol; Renin

1977
The physiology of blood pressure regulation--normal and abnormal.
    Pediatric annals, 1977, Volume: 6, Issue:6

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Child; Glomerular Filtration Rate; Hemo

1977
[Radioimmunological determination of aldosterone in the serum. New method for the localization of aldosteronism].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1977, Mar-15, Volume: 32, Issue:6

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Posture; Radioimmunoassay; Renin

1977
Steroid profile in a case of adrenal carcinoma with severe hypertension.
    American journal of clinical pathology, 1977, Volume: 67, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Aldost

1977
Production of sustained hypertension by chronic intrarenal norepinephrine infusion in conscious dogs.
    Circulation research, 1977, Volume: 40, Issue:5 Suppl 1

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female

1977
Multifactorial analysis of chronic hypertension induced by electrolyte-active steroids in trained, unanesthetized dogs.
    Circulation research, 1977, Volume: 40, Issue:5 Suppl 1

    Topics: Acebutolol; Aldosterone; Animals; Chronic Disease; Clonidine; Corticosterone; Diet, Sodium-Restricte

1977
Evidence for an unidentified steroid in a child with apparent mineralocorticoid hypertension.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:5

    Topics: 17-Ketosteroids; Aldosterone; Blood Pressure; Body Weight; Child, Preschool; Chlorothiazide; Dexamet

1977
Aldosterone regulation in essential hypertension: altered adrenal responsiveness to angiotensin II.
    Mayo Clinic proceedings, 1977, Volume: 52, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Infusions, Parenteral; Male; Postu

1977
Altered renin-angiotensin-aldosterone relationships in normal renin essential hypertension.
    Circulation research, 1977, Volume: 41, Issue:2

    Topics: Adrenal Cortex; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans;

1977
[The value of stimulation of the renin-angiotensin-aldosterone system as a screening test for hypertension (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1977, May-06, Volume: 102, Issue:18

    Topics: Adult; Aldosterone; Angiotensin II; Diuretics; Furosemide; Humans; Hypertension; Male; Middle Aged;

1977
The antihypertensive action of methyldopa in relation to its effect on the renin-aldosterone system.
    Journal of clinical pharmacology, 1977, Volume: 17, Issue:7

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Body Weight; Humans; Hypertension; Hypertensio

1977
Aids in the diagnosis of hypertension.
    Angiology, 1977, Volume: 28, Issue:8

    Topics: Aldosterone; Angiotensin II; Cardiovascular Diseases; Diuretics; Humans; Hyperaldosteronism; Hyperte

1977
Experimental aldosterone hypertension in the rat.
    Canadian journal of physiology and pharmacology, 1977, Volume: 55, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Chlorisondamine; Desoxycorticosterone; Drug Interactions; Etha

1977
[Pattern of aldosterone and catecholamines in patients with essential hypertension and differnet plasma renin activity].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1977, Jul-11, Volume: 32, Issue:28

    Topics: Adult; Aldosterone; Catecholamines; Female; Humans; Hypertension; Male; Middle Aged; Renin

1977
Low renin hypertension.
    Contributions to nephrology, 1977, Volume: 8

    Topics: Adrenal Cortex; Aldosterone; Humans; Hydrocortisone; Hypertension; Metal Metabolism, Inborn Errors;

1977
[Stimulation of renin-angiotensin-aldosterone system as screening test for hypertension].
    Deutsche medizinische Wochenschrift (1946), 1977, Jul-15, Volume: 102, Issue:28

    Topics: Aldosterone; Angiotensin II; Furosemide; Humans; Hypertension; Methods; Propranolol; Renin

1977
Age- and posture-related changes in plasma protein binding and metabolism of aldosterone in essential and secondary hypertension.
    The Journal of laboratory and clinical medicine, 1977, Volume: 90, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aldosterone; Blood Proteins; Female; Humans; Hypertension; Male; Met

1977
Frequency of surgical treatment for hypertension in adults at the Mayo Clinic from 1973 through 1975.
    Mayo Clinic proceedings, 1977, Volume: 52, Issue:9

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Female; Humans; Hypertension

1977
[The effect of upright posture on plasma aldosterone concentration in arterial hypertension (author's transl)].
    Casopis lekaru ceskych, 1977, Aug-05, Volume: 116, Issue:31

    Topics: Aldosterone; Humans; Hypertension; Posture

1977
Influence of beta-blockade on aldosterone metabolism under normal and low sodium diet in man.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1977, Volume: 27, Issue:6

    Topics: Acebutolol; Adult; Aldosterone; Angiotensins; Diet, Sodium-Restricted; Humans; Hypertension; Male; M

1977
[The renin-angiotensin-aldosterone system in hypertensive patients. II. Diagnosis of primary hyperaldosteronism].
    La Nouvelle presse medicale, 1977, Sep-10, Volume: 6, Issue:29

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adult; Aldosterone; Blo

1977
Urinary kallikrein in normal renin essential hypertension.
    Circulation, 1977, Volume: 56, Issue:5

    Topics: Adult; Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Kallikreins; Male; Renin; Sodium

1977
[The renin-aldosterone system in essential hypertension--aging, low renin hypertension and the relation between renin secretion and aldosterone secretion--].
    Nihon Naibunpi Gakkai zasshi, 1977, Jul-20, Volume: 53, Issue:7

    Topics: Adult; Aged; Aging; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Middle Aged; Renin

1977
[Effects of an analogue of angiotensin II, [Sar1,Ile8] ATII, on blood pressure, plasma renin activity and plasma aldosterone in various forms of hypertension].
    Nihon Naibunpi Gakkai zasshi, 1977, Jul-20, Volume: 53, Issue:7

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Hypertension

1977
[Effects of acute sodium depletion on blood pressure and renin-angiotensin-aldosterone system in patients with benign essential hypertension (author's transl)].
    Fukuoka igaku zasshi = Hukuoka acta medica, 1977, Volume: 68, Issue:8

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Electrolytes; Female; H

1977
Inappropriate secretion of antiduretic hormone, hypertension, and hypoplastic corpus callosum.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 45, Issue:4

    Topics: Adolescent; Agenesis of Corpus Callosum; Aldosterone; Angiotensin II; Arginine Vasopressin; Blood Pr

1977
Disparate patterns of aldosterone response during diuretic treatment of hypertension.
    Annals of internal medicine, 1977, Volume: 87, Issue:5

    Topics: Adult; Aldosterone; Body Weight; Chlorthalidone; Female; Humans; Hypertension; Male; Middle Aged; Pu

1977
Age and the renin-aldosterone system.
    Archives of internal medicine, 1977, Volume: 137, Issue:10

    Topics: Adolescent; Adult; Age Factors; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Mid

1977
[Antihypertensive effects of coenzyme Q10 in essential hypertension--in relation to the renin-aldosterone system].
    Horumon to rinsho. Clinical endocrinology, 1977, Volume: 25, Issue:9

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Female; Humans; Hypertension; Male; Middle Aged;

1977
Retardation in the development of spontaneous hypertension in SH rats by gonadectomy.
    The Journal of laboratory and clinical medicine, 1977, Volume: 90, Issue:6

    Topics: Adrenal Glands; Aldosterone; Animals; Body Weight; Castration; Corticosterone; Desoxycorticosterone;

1977
The renin-angiotensin system in hypertension.
    The Journal of the Maine Medical Association, 1977, Volume: 68, Issue:11

    Topics: Aldosterone; Angiotensins; Diuretics; Humans; Hypertension; Juxtaglomerular Apparatus; Propranolol;

1977
[The renin-angiotensin-aldosterone system in essential arterial hypertension].
    Revista clinica espanola, 1977, Sep-15, Volume: 146, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Female; Furosemide; Humans; Hyper

1977
[The effects of clonidine on the renin-angiotensin-aldosterone system in patients with hypertension].
    Revista clinica espanola, 1977, Sep-15, Volume: 146, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Clonidine; Drug Evaluation; Female; Humans; Hype

1977
Factors influencing the choice of antihypertensive agents.
    Postgraduate medicine, 1976, Volume: 60, Issue:7

    Topics: Age Factors; Aldosterone; Cerebrovascular Disorders; Clonidine; Depression; Diabetes Complications;

1976
[Simple determination of urinary aldosterone without chromatography].
    Horumon to rinsho. Clinical endocrinology, 1976, Volume: 24, Issue:1

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Radioimmunoassay

1976
Nomograms relating aldosterone excretion to urinary sodium and potassium in the pediatric population: their application to the study of childhood hypertension.
    The American journal of cardiology, 1976, Mar-31, Volume: 37, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Child, Preschool; Circadian Rhythm; Humans; Hypertension; Infant; In

1976
Dissociation of plasma renin activity and aldosterone in essential hypertension.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 43, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aldosterone; Humans; Hypertension; Middle Aged; Renin

1976
[Recent progress concerning the pathogenesis of arterial hypertension].
    Minerva medica, 1976, Jun-30, Volume: 67, Issue:32

    Topics: Affective Symptoms; Aldosterone; Blood Pressure; Elasticity; Heart Rate; Humans; Hyperaldosteronism;

1976
Renin, aldosterone and arterial pressure responses to acute beta-adrenergic receptor blockage in hypertensive patients.
    Klinische Wochenschrift, 1976, Aug-15, Volume: 54, Issue:16

    Topics: Adult; Aldosterone; Blood Pressure; Circadian Rhythm; Humans; Hypertension; Male; Pindolol; Proprano

1976
[Significance of certain humoral factors in the pathogenesis of hypertension in pregnancy].
    Akusherstvo i ginekologiia, 1976, Issue:1

    Topics: Aldosterone; Female; Humans; Hypertension; Potassium; Pregnancy; Pregnancy Complications, Cardiovasc

1976
A delayed suppression of the renin-aldosterone axis following saline infusion in human hypertension.
    Circulation research, 1976, Volume: 39, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Female; Humans; Hypertension; Infus

1976
Clinical pharmacology of angiotensin antagonists.
    Federation proceedings, 1976, Volume: 35, Issue:13

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Humans; Hypertension; Radioimmunoassa

1976
The effect of saralasin (1sar-8-ala-angiotensin II) on blood pressure in patients with Cushing's syndrome.
    Klinische Wochenschrift, 1976, Jul-15, Volume: 54, Issue:14

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Cushing Syndrome; Female; Humans; Hyperaldosteronism; H

1976
Reciprocal relation between renin dependency and sodium dependency in essential hypertension.
    The New England journal of medicine, 1976, Dec-02, Volume: 295, Issue:23

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Feedback; Humans; Hypertension; Kidney; Middle A

1976
[Relationship between hormone concentration in peripheral blood in hypertension, arteriosclerosis and obesity].
    Terapevticheskii arkhiv, 1976, Volume: 48, Issue:4

    Topics: Adult; Aldosterone; Arteriosclerosis; Female; Hormones; Humans; Hydrocortisone; Hypertension; Insuli

1976
[A critical review of hypothetical causes of EPH-gestosis].
    Zentralblatt fur Gynakologie, 1976, Volume: 98, Issue:18

    Topics: Aldosterone; Angiotensin II; Animals; Biogenic Amines; Blood Volume; Body Fluids; Edema; Female; Fib

1976
Relationship between plasma aldosterone concentration and plasma potassium in patients with essential hypertension during alprenolol treatment.
    Acta medica Scandinavica, 1976, Volume: 200, Issue:4

    Topics: Adult; Aldosterone; Alprenolol; Blood Pressure; Female; Humans; Hypertension; Male; Potassium; Renin

1976
The renal prostaglandins and blood pressure regulation.
    Advances in prostaglandin and thromboxane research, 1976, Volume: 2

    Topics: Aldosterone; Binding Sites; Blood Pressure; Diuresis; Furosemide; Humans; Hypertension; Indomethacin

1976
Benign desoxycorticosterone-producing adrenal tumor.
    JAMA, 1976, Aug-30, Volume: 236, Issue:9

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Cholesterol; Desoxycorticosterone; Female; Humans; Hydr

1976
[Evaluation of plasma remin activity and urinary excretion of aldosterone in subjects with clinically essential hypertension].
    Minerva cardioangiologica, 1976, Volume: 24, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin

1976
[Sodium, hypertension and diuretics].
    Terapevticheskii arkhiv, 1976, Volume: 48, Issue:9

    Topics: Aldosterone; Angiotensin II; Benzothiadiazines; Diuretics; Humans; Hypertension; Renin; Sodium; Sodi

1976
Renin and aldosterone suppression in the antihypertensive action of clonidine.
    The American journal of cardiology, 1976, Nov-23, Volume: 38, Issue:6

    Topics: Adult; Aldosterone; Clonidine; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle A

1976
Acute and chronic dose-response relationships for angiotensin, aldosterone, and arterial pressure at varying levels of sodium intake.
    Circulation research, 1976, Volume: 39, Issue:6

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Diet; Dogs; Dose-Response Relationship, Drug;

1976
Studies of the renin-angiotension-aldosterone system, cortisol, DOC, and ADH in normal and hypertensive pregnancy.
    Perspectives in nephrology and hypertension, 1976, Volume: 5

    Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Angiotensinogen; Arginine Vasopressin; Cortico

1976
Sequential changes in the renin--angiotensin--aldosterone systems and plasma progesterone concentration in normal and abnormal human pregnancy.
    Perspectives in nephrology and hypertension, 1976, Volume: 5

    Topics: Aldosterone; Angiotensin II; Angiotensinogen; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy

1976
[Endocrine disorders in patients with essential hypertension].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1976, Sep-15, Volume: 31, Issue:18

    Topics: Aldosterone; Angiotensin II; Catecholamines; Humans; Hypertension; Prostaglandins; Renin

1976
[Effect of diazoxide on blood pressure, PRA and plasma aldosterone in hypertensive patients (author's transl)].
    Giornale italiano di cardiologia, 1976, Volume: 6, Issue:7

    Topics: Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Diazoxide; Humans; Hyperaldosteronism; Hyperte

1976
[Evaluation of the plasma renin activity and urinary aldosterone excretion in patients with essential hypertension treated with spironolactone. Note II].
    Minerva cardioangiologica, 1976, Volume: 24, Issue:5

    Topics: Adult; Aldosterone; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged; Renin; Spirono

1976
[Plasma renin activity and plasma aldosterone in essential hypertension: effect of age and diastolic blood pressure].
    Schweizerische medizinische Wochenschrift, 1976, Dec-04, Volume: 106, Issue:49

    Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Creatinine; Furosemide; Humans; Hypertension; Middle Ag

1976
[Physiopathology of arterial hypertension. Role of the nervous system and of the hormones].
    Schweizerische medizinische Wochenschrift, 1976, Dec-11, Volume: 106, Issue:50

    Topics: Aldosterone; Animals; Bradykinin; Brain; Catecholamines; Hormones; Humans; Hyperaldosteronism; Hyper

1976
[Rectal electrical potential difference and plasma aldosterone in hyperaldosteronism and low-, normal- and high-renin hypertension].
    Wiener klinische Wochenschrift, 1976, Dec-10, Volume: 88, Issue:23

    Topics: Action Potentials; Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male;

1976
[Relationship between renin-aldosterone system and efficacy of a beta-blocking agent in hypertensive patients].
    La Clinica terapeutica, 1976, Oct-15, Volume: 79, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle

1976
Changes of blood pressure, plasma renin activity and plasma aldosterone concentration following the infusion of Sar1-Ile8-angiotensin II in hypertensive, fluid and electrolyte disorders.
    Progress in biochemical pharmacology, 1976, Volume: 12

    Topics: Acidosis, Renal Tubular; Aldosterone; Angiotensin II; Bartter Syndrome; Blood Pressure; Cushing Synd

1976
The effects of the angiotensin II antagonist saralasin on blood pressure and plasma aldosterone in man in relation to the prevailing plasma angiotensin II concentration.
    Progress in biochemical pharmacology, 1976, Volume: 12

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Diet; Humans; Hyperaldosteronism; Hypertension; Kidney

1976
[Relationship between plasma-renin and plasma-aldosterone in patients with essential hypertension and in healthy persons].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1976, Volume: 82 Pt 2

    Topics: Aldosterone; Humans; Hypertension; Posture; Renin

1976
[Aldosterone excretion, cortisol and corticosterone plasma concentration in patients with essential hypertension under sodium load].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1976, Volume: 82 Pt 2

    Topics: Aldosterone; Corticosterone; Humans; Hydrocortisone; Hypertension; Sodium

1976
[Influence of propranolol on plasma-renin activity, plasma-aldosterone concentration and blood pressure in patients with essential hypertension].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1976, Volume: 82 Pt 2

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Propranolol; Renin

1976
[Acute and chronic beta-receptor blockade: influence on blood pressure and on the renin-angiotensin-aldosterone system in essential hypertension].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1976, Volume: 82 Pt 2

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Pindolol; Propranolol; Pulse; Ren

1976
[Correlations between plasmatic renin and aldosterone in essential arterial hypertension with sympathetic hyperactivity].
    Bollettino della Societa italiana di cardiologia, 1976, Volume: 21, Issue:3

    Topics: Aldosterone; Female; Humans; Hypertension; Male; Renin; Sympathetic Nervous System

1976
[Plasma aldosterone and renin activities in various types of hypertension].
    Horumon to rinsho. Clinical endocrinology, 1976, Volume: 24, Issue:5

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin

1976
[Changes of arterial pressure and biosynthesis of corticosteroids in rats with neurogenic stress].
    Kardiologiia, 1976, Volume: 16, Issue:9

    Topics: Aldosterone; Animals; Blood Pressure; Corticosterone; Desoxycorticosterone; Humans; Hypertension; Ma

1976
The renal humoral system: a cause of hypertension?
    RN, 1975, Volume: 38, Issue:9

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Kidney; Renin

1975
Hypertension and renal diseases.
    The Journal of the American Association of Nephrology Nurses & Technicians, 1975, Volume: 2, Issue:2

    Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Humans; Hypertension; Hypertension, Malignant;

1975
Outpatient screening tests for primary aldosteronism.
    Australian and New Zealand journal of medicine, 1976, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Aged; Aldosterone; Fludrocortisone; Humans; Hyperaldosteronism; Hypertension; Mid

1976
Aldosterone excretion rate in normal subjects and hypertensive patients.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1976, Volume: 75, Issue:7

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Sodium

1976
The effects of saralasin, an angiotensin II antagonist, on blood pressure and the renin-angiotensin-aldosterone system in normal and hypertensive subjects.
    Australian and New Zealand journal of medicine, 1976, Volume: 6, Issue:3 Suppl

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Depression, Chemical; Diet; Female; Humans; Hype

1976
Effects of aldosterone and spironolactone on arterial renin in rats.
    Clinical science and molecular medicine. Supplement, 1976, Volume: 3

    Topics: Aldosterone; Animals; Aorta; Hypertension; Male; Rats; Renin; Spironolactone; Subcellular Fractions

1976
Solitary kidney and ageing as causes of low renin and aldosterone concentrations: relevance to "low-renin" essential hypertension.
    Clinical science and molecular medicine. Supplement, 1976, Volume: 3

    Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Glomerular Filtration Rate; Humans; Hypertension; Kidne

1976
Determination of renin-dependency and sodium-dependency in the three renin sub-groups of essential hypertension.
    Clinical science and molecular medicine. Supplement, 1976, Volume: 3

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Renin; Saralasin; Sodium

1976
Synthesis of endocrine control in hypertension.
    Clinical science and molecular medicine. Supplement, 1976, Volume: 3

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dogs; Feedback; Hypertension; Kidney; Potassiu

1976
Role of steroids in hypertension: evaluation of plasma mineralocorticoid activity with aldosterone receptors.
    Clinical science and molecular medicine. Supplement, 1976, Volume: 3

    Topics: Aldosterone; Animals; Binding, Competitive; Desoxycorticosterone; Humans; Hydrocortisone; Hypertensi

1976
Haemodynamic and endocrinological changes during anti-hypertensive treatment with a new vasodilator substance (L6150) and propranolol.
    Clinical science and molecular medicine. Supplement, 1976, Volume: 3

    Topics: Adult; Aged; Aldosterone; Cardiac Output; Drug Therapy, Combination; Female; Humans; Hypertension; K

1976
The use of angiotensin-converting enzyme inhibitor in the diagnosis and treatment of hypertension.
    Clinical science and molecular medicine. Supplement, 1975, Volume: 2

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Drug Evaluation; Female; Hu

1975
18-hydroxylated steroids in human hypertension - clinical study.
    Endocrinologia experimentalis, 1976, Volume: 10, Issue:1

    Topics: 18-Hydroxydesoxycorticosterone; Adolescent; Adult; Aged; Aldosterone; Female; Humans; Hydroxylation;

1976
Mineralocorticoid like effect of new 18-hydroxy-steroid isolated from urine of hypertensive patients.
    Endocrinologia experimentalis, 1976, Volume: 10, Issue:1

    Topics: 18-Hydroxydesoxycorticosterone; Adrenalectomy; Aldosterone; Animals; Hydroxylation; Hydroxyprogester

1976
Role of juxtagolmerular apparatus in renal allograft rejection.
    New York state journal of medicine, 1975, Volume: 75, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Dogs; Erythropoietin; Glomerular Filtration Rate; Graft Reject

1975
Renin and hypertension.
    Postgraduate medicine, 1975, Volume: 57, Issue:2

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Diuretics; Hyperaldosteronism; Hypertension; Juxtaglome

1975
Hypertension corrected by discontinuing chronic sodium bicarbonate ingestion. Subsequent transient hypoaldosteronism.
    The American journal of medicine, 1975, Volume: 58, Issue:2

    Topics: 17-Hydroxycorticosteroids; Aldosterone; Angiotensin II; Antihypertensive Agents; Bicarbonates; Calci

1975
Adrenal steroidogenesis in the spontaneously hypertensive rat (SHR).
    Endocrinology, 1975, Volume: 96, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Age Factors; Aldosterone; Animals; Catheterization; Cortico

1975
[Changes in the biosynthesis of corticosteroids from progesterone-C14 under the effect of prostaglandin E2 in rabbits with vasorenal hypertension].
    Kardiologiia, 1975, Volume: 15, Issue:1

    Topics: Adrenal Glands; Aldosterone; Animals; Carbohydrate Metabolism; Carbon Radioisotopes; Corticosterone;

1975
Workup of the newly discovered hypertensive patient.
    Postgraduate medicine, 1975, Volume: 57, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Cardiac Output; Cerebrovascular Disorders; Contraceptives, Oral;

1975
Role of blood pressure in cardiovascular disease: the Framingham Study.
    Angiology, 1975, Volume: 26, Issue:1 Pt. 1

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Cardiovascular Diseases; Cholesterol; Coronary Disease; De

1975
Pathophysiology of angiotensin-salt hypertension.
    The Journal of laboratory and clinical medicine, 1975, Volume: 85, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Blood Urea Nitrogen; Body Weight; Calcium; Corticosterone; Des

1975
Suppression of renin and aldosterone by small amounts of DOCA in normal man.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:4

    Topics: Adult; Aldosterone; Body Weight; Depression, Chemical; Desoxycorticosterone; Diet, Sodium-Restricted

1975
Effects of high and low sodium intake on arterial pressure and forearm vasular resistance in borderline hypertension. A preliminary report.
    Circulation research, 1975, Volume: 36, Issue:6 Suppl 1

    Topics: Adult; Aldosterone; Blood Flow Velocity; Blood Pressure; Body Weight; Central Venous Pressure; Creat

1975
[Renin, angiotensin and aldosterone in the diagnosis of hypertension].
    Duodecim; laaketieteellinen aikakauskirja, 1975, Volume: 91, Issue:7

    Topics: Aldosterone; Angiotensin II; Blood Volume; Diagnosis, Differential; Humans; Hypertension; Hypertensi

1975
[Essential hypertension and the renin-angiotensin-aldosterone system].
    Kardiologia polska, 1975, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Humans; Hypertension; Middle Aged; Renin

1975
Plasma renin and aldosterone in an abdominal pregnancy with toxemia.
    American journal of obstetrics and gynecology, 1975, Jul-01, Volume: 122, Issue:5

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Ischemia; Placenta; Pre-Eclampsia; Pregnancy; Preg

1975
Editorial: Low renin "essential'' hypertension; a variant of classic primary aldosteronism?
    Archives of internal medicine, 1975, Volume: 135, Issue:2

    Topics: Adrenal Cortex; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

1975
Control of aldosterone secretion in the spontaneously hypertensive rat.
    Circulation research, 1975, Volume: 37, Issue:1

    Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone; Hyperte

1975
Proceedings: Steroid production rates in two patients with corticosterone-producing adenomata.
    The Journal of endocrinology, 1975, Volume: 65, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Corticosterone; Female; Hum

1975
Effect of acute volume depletion on blood pressure, plasma renin activity and plasma aldosterone concentration in hypertensive subjects.
    Japanese circulation journal, 1975, Volume: 39, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aldosterone; Blood Pressure; Body Fluids; Electrolytes; Female; Fu

1975
Effect of pressor agents on blood pressure, plasma renin activity and plasma aldosterone concentration in essential hypertension.
    Japanese heart journal, 1975, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hyperaldosteronism;

1975
[Plasma aldosterone and plasma renin activity in patients with essential and renal hypertension under acute stimulation with saline depletion and acute suppression with saline infusion].
    Klinische Wochenschrift, 1975, Mar-01, Volume: 53, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Female; Furosemide; Glomerulonephritis;

1975
Letter: Adrenal tumours and hypertension.
    British medical journal, 1975, Aug-09, Volume: 3, Issue:5979

    Topics: Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension

1975
Therapy and prognosis of hypertension in chronic nephritis.
    Japanese circulation journal, 1975, Volume: 39, Issue:7

    Topics: Adult; Aldosterone; Angiotensin II; Blood Volume; Catecholamines; Chronic Disease; Creatinine; Extra

1975
Proceedings: Changes of plasma renin activity and plasma aldosterone by aging of spontaneously hypertensive rat, and their relationship with blood pressure.
    Japanese heart journal, 1975, Volume: 16, Issue:3

    Topics: Aging; Aldosterone; Animals; Disease Models, Animal; Hypertension; Rats; Renin

1975
Deoxycorticosterone excretion in normal, hypertensive and hypokalaemic subjects.
    Clinical science and molecular medicine, 1975, Volume: 48, Issue:2

    Topics: Aldosterone; Animals; Bicarbonates; Blood Pressure; Cross Reactions; Desoxycorticosterone; Humans; H

1975
[Spironolactone and thiabutazide in the treatment of essential hypertension (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, Mar-21, Volume: 100, Issue:12

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Body Weight; Butanes; Female; Furosemide; Huma

1975
[Renin-angiotensin - aldosterone system in essential hypertension].
    Horumon to rinsho. Clinical endocrinology, 1975, Volume: 23, Issue:5

    Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Radioimmunoassay; Renin

1975
Extensive hypertensive work-up: pro.
    JAMA, 1975, Jan-27, Volume: 231, Issue:4

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Antihypertensive Agents; Attitude to Health; Epidemiolo

1975
Response of plasma aldosterone to fludrocortisone in primary hyperaldosteronism and other forms of hypertension.
    Clinical endocrinology, 1975, Volume: 4, Issue:5

    Topics: Adenocarcinoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Aldosterone; Desoxycorticost

1975
[Liquorice syndrome].
    Duodecim; laaketieteellinen aikakauskirja, 1975, Volume: 91, Issue:9

    Topics: Adult; Aldosterone; Female; Glycyrrhiza; Humans; Hypertension; Hypokalemia; Plants, Medicinal; Renin

1975
[Hypertension and oral contraceptives. Own experiences].
    Ugeskrift for laeger, 1975, Oct-13, Volume: 137, Issue:42

    Topics: Adult; Aldosterone; Contraceptives, Oral; Female; Humans; Hypertension; Middle Aged; Renin

1975
Selection of patients and operative approach in primary aldosteronism.
    Annals of surgery, 1975, Volume: 182, Issue:4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands;

1975
Effects of unilateral nephrectomy in man on renin, aldosterone and volume/pressure relationships.
    Clinical and experimental pharmacology & physiology, 1975, Volume: Suppl 2

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Kidney; Male; Nephrectomy; Pla

1975
The classification and treatment of essential hypertension using the renin-sodium index for vasoconstriction-volume analysis.
    The Johns Hopkins medical journal, 1975, Volume: 137, Issue:4

    Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Animals; Antihypertensive Agents; Blood Pressure;

1975
Mineralocorticoid activity in patients in the early benign phase of essential hypertension.
    Journal of steroid biochemistry, 1975, Volume: 6, Issue:5

    Topics: Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Liver; Middle Aged; Progesterone; Renin

1975
Adrenal steroidogenesis in "low renin" or hyporeninemic hypertension.
    Journal of steroid biochemistry, 1975, Volume: 6, Issue:5

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Biological Assa

1975
[Clinical importance of the renin-angiotensin-aldosterone system in hypertension].
    Medizinische Monatsschrift, 1975, Volume: 29, Issue:9

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Renin

1975
Hypertension, oedema, and suppressed renin aldosterone system due to unsupervised salt administration.
    Archives of disease in childhood, 1975, Volume: 50, Issue:5

    Topics: Aldosterone; Child, Preschool; Diarrhea, Infantile; Edema; Female; Glucose; Humans; Hypernatremia; H

1975
Comparison between the effects of ST 600 and clonidine.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 217, Issue:1

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Volume; Cardiac Output; Clo

1975
Oral contraceptive pill hypertension.
    The Journal of reproductive medicine, 1975, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Body Weight; Contracep

1975
[Effects of acebutolol on the renin-aldosterone system in essential arterial hypertension].
    La Nouvelle presse medicale, 1975, Dec-31, Volume: 4, Issue:46 Suppl

    Topics: Acebutolol; Adolescent; Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Humans; Hyperte

1975
[Renin-angiotensin-aldosterone system in hypertensive disease and arteriosclerotic myocardioslcerosis complicated by chronic circulatory insufficiency].
    Vrachebnoe delo, 1975, Issue:7

    Topics: Aged; Aldosterone; Angiotensin II; Blood Circulation; Chronic Disease; Coronary Disease; Female; Hum

1975
[Behavior of blood pressure during oral hormonal anticonception].
    Zeitschrift fur arztliche Fortbildung, 1975, Sep-01, Volume: 69, Issue:17

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Contraceptives

1975
Water, sodium, potassium, and electrolyte balance.
    Progress in food & nutrition science, 1975, Volume: 1, Issue:10

    Topics: Aged; Aldosterone; Child, Preschool; Diet; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Hype

1975
[Diazoxide test in the diagnosis of arterial hypertension: modifications in the levels of renin and aldosterone in blood of patients with various restrains of the renal function].
    Quaderni Sclavo di diagnostica clinica e di laboratorio, 1975, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Diazoxide; Humans; Hyperaldosteronism; Hypertension; Kidney Diseases

1975
[Changes in the corticosteroids and their alpha-ketol metabolites in the urine of hypertension patients treated with metopirons].
    Vutreshni bolesti, 1975, Volume: 14, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aldosterone; Circadian Rhythm; Cortodoxone; Desoxycortic

1975
Hypertension as a disease of modern society.
    International journal of health services : planning, administration, evaluation, 1975, Volume: 5, Issue:4

    Topics: Adaptation, Psychological; Aldosterone; Blood Pressure; Diet; Humans; Hypertension; Life Style; Soci

1975
[Interference of canrenoate potassium with plasma renin activity. Note I. Effects of canrenoate potassiumon plasma renin activity in patients with essential hypertension].
    Bollettino della Societa italiana di biologia sperimentale, 1975, Dec-30, Volume: 51, Issue:24

    Topics: Adult; Aged; Aldosterone; Canrenoic Acid; Electrolytes; Female; Humans; Hypertension; Male; Middle A

1975
[Renin and aldosterone].
    Annali dell'Istituto superiore di sanita, 1975, Volume: 11, Issue:1-2

    Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Juxtaglomerular Apparatus; Li

1975
Stimulated renin: a screening test for hypertension.
    Annals of internal medicine, 1975, Volume: 82, Issue:1

    Topics: Adult; Aged; Aldosterone; Diagnosis, Differential; Evaluation Studies as Topic; Female; Furosemide;

1975
[Clinical and etiological studies of glucocorticoid-reactive hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1975, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Female; Glucocorticoids; Humans; Hypertension; Male; Middle Aged; Po

1975
[Hypertension in the aged. (4) Renal and hormonal factors].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1975, Volume: 12, Issue:4

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Catecholamines; Desoxycorticosterone; Hormones; Humans; Hy

1975
[A reduced aldosterone response to infused angiotensin II in low renin essential hypertension (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1975, Aug-10, Volume: 64, Issue:8

    Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin

1975
[Experimental studies on the determination of serum aldosterone by direct extraction using aldosterone-radioimmunoassay-kit (CIS) but without chromatography].
    Horumon to rinsho. Clinical endocrinology, 1975, Volume: 23, Issue:11

    Topics: Adrenal Gland Diseases; Aldosterone; Humans; Hypertension; Radioimmunoassay

1975
[Functional state and reactivity of the adrenal cortex in rats with hereditarily conditioned hypertension].
    Kardiologiia, 1975, Volume: 15, Issue:10

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Animals; Blood Pressure; Human

1975
[Physiopathology and clinical aspects of primary hyperaldosteronism].
    Recenti progressi in medicina, 1975, Volume: 59, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Proteinuri

1975
Low renin essential hypertension in a child.
    Helvetica paediatrica acta, 1976, Volume: 30, Issue:4-5

    Topics: Aldosterone; Child; Circadian Rhythm; Dexamethasone; Humans; Hydrochlorothiazide; Hydrocortisone; Hy

1976
Location of aldosterone-producing adenomas with 131I-19-iodocholesterol.
    The New England journal of medicine, 1976, Feb-19, Volume: 294, Issue:8

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cholesterol; Humans; Hyperaldosteronism; Hypertension

1976
Editorial: Solving the adrenal lesion(s) of primary aldosteronism.
    The New England journal of medicine, 1976, Feb-19, Volume: 294, Issue:8

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cholesterol; Humans; Hyperaldosteronism; Hypertension

1976
Mineralocorticoid secretion in essential hypertension with normal and low plasma renin activity.
    Circulation, 1976, Volume: 53, Issue:3

    Topics: 18-Hydroxycorticosterone; Adult; Aldosterone; Corticosterone; Desoxycorticosterone; Humans; Hyperten

1976
The effect of dietary sodium chloride on blood pressure, body fluids, electrolytes, renal function, and serum lipids of normotensive man.
    The Journal of laboratory and clinical medicine, 1976, Volume: 87, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Body Fluids; Body Weight; Cholesterol; Diet, Sodium-Restricted;

1976
[Diurnal variation in the urinary excretion of vanilmandelic acid and aldosterone in normal and hypertensive persons (author's transl)].
    Klinische Wochenschrift, 1976, Feb-01, Volume: 54, Issue:3

    Topics: Adult; Aldosterone; Circadian Rhythm; Creatinine; Female; Humans; Hyperaldosteronism; Hypertension;

1976
[Principle and range of application of radioimmunoassay. (V). The renin-angiontensin-aldosterone system].
    Die Medizinische Welt, 1976, Feb-13, Volume: 27, Issue:7

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Juxtaglomerular Apparatus; Radioimmunoassay; Reni

1976
Renin-angiotensin-aldosterone system in experimental renal hypertension in the rabbit.
    The American journal of physiology, 1976, Volume: 230, Issue:2

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Corticost

1976
Suppression of the renin-aldosterone system in mild essential hypertension.
    Clinical science and molecular medicine, 1976, Volume: 50, Issue:4

    Topics: Adult; Aldosterone; Extracellular Space; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Po

1976
Aldosterone metabolic clearance is normal in low-renin essential hypertension.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 42, Issue:4

    Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Body Surface Area; Female; Hum

1976
[Primary aldosteronism].
    Schweizerische medizinische Wochenschrift, 1976, Apr-03, Volume: 106, Issue:14

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Aldosterone; Antihyp

1976
Enflurane anaesthesia for removal of aldosterone producing adenoma.
    Der Anaesthesist, 1976, Volume: 25, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Anesthesia, Inhalation; Blood Pressure; Enflur

1976
Relation between plasma renin activity, angiotensin, and aldosterone and blood pressure in mild untreated hypertension.
    Circulation research, 1976, Volume: 38, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Arteries; Blood Pressure; Diet; Female; Humans; Hype

1976
Urine aldosterone radioimmunoassay: validation of a method without chromatography.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 42, Issue:5

    Topics: Adrenal Gland Diseases; Aldosterone; Chromatography, Paper; Cushing Syndrome; Humans; Hyperaldostero

1976
Triamterene-induced changes in aldosterone and renin values in essential hypertension. Evidence of a role for aldosterone in preventing blood pressure reduction.
    Archives of internal medicine, 1976, Volume: 136, Issue:6

    Topics: Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Renin; Sodi

1976
Nilvadipine in hypertension with renal dysfunction.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 6

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Creatinine; Female; Heart Rate; H

1992
[Liddle syndrome (or pseudo-hyperaldosteronism). Long-term development and erythrocyte potassium flow study in 4 cases].
    Archives francaises de pediatrie, 1992, Volume: 49, Issue:8

    Topics: Aldosterone; Alkalosis; Cell Membrane Permeability; Child; Child, Preschool; Erythrocyte Membrane; F

1992
Subdiaphragmatic vagotomy in rats induces systemic hypertension and sodium retention.
    Mineral and electrolyte metabolism, 1992, Volume: 18, Issue:6

    Topics: Aldosterone; Animals; Corticosterone; Female; Hypertension; Potassium; Rats; Rats, Sprague-Dawley; R

1992
Adrenal renin is released into the circulation of the hypertensive transgenic rat TGR (mRen-2)27.
    Transactions of the Association of American Physicians, 1992, Volume: 105

    Topics: Adrenal Glands; Aldosterone; Animals; Cells, Cultured; Dexamethasone; Disease Models, Animal; Hypert

1992
Twenty-four year spironolactone therapy in an aged patient with aldosterone-producing adenoma.
    Acta endocrinologica, 1992, Volume: 126, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aged; Aldosterone; Fe

1992
Mineralocorticoids and mineralocorticoid receptors in mononuclear leukocytes in patients with pregnancy-induced hypertension.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 74, Issue:4

    Topics: 18-Hydroxycorticosterone; Aldosterone; Female; Humans; Hypertension; Leukocytes, Mononuclear; Minera

1992
Suppression of the renin-angiotensin-aldosterone axis with erythropoietin therapy by a negative feedback loop.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1992, Volume: 7, Issue:2

    Topics: Adult; Aged; Aldosterone; Anemia; Erythropoietin; Feedback; Hemoglobins; Humans; Hypertension; Middl

1992
The role of the adrenal gland in hypertensive transgenic rat TGR(mREN2)27.
    Endocrinology, 1992, Volume: 131, Issue:2

    Topics: 18-Hydroxycorticosterone; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Animals

1992
[Adrenal corticosteroid and disease models of hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Desoxycorticoster

1992
[Effect of antihypertensive therapy with captopril on gluco- and mineralocorticoid receptors of peripheral blood lymphocytes in hypertensive patients of various age].
    Kardiologiia, 1992, Volume: 32, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Captopril; Female; Humans; Hypertension; Lymphoc

1992
The role of atrial natriuretic peptide in natriuresis of fasting.
    Journal of hypertension, 1992, Volume: 10, Issue:9

    Topics: Adolescent; Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Fasting; Female; Humans; Hypertensi

1992
Plasma 19-hydroxy-androstenedione (19-OH-A) in essential hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1992, Volume: 14, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Androstenedione; Catecholamines; Exercise Test; Hum

1992
Do opioid receptors participate in the regulation of atrial natriuretic peptide (ANP) secretion in hypertensive patients?
    Clinical nephrology, 1992, Volume: 38, Issue:4

    Topics: Adult; Aldosterone; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; Female; Humans;

1992
[The interrelationship between humoral factors and the indices of left ventricular myocardial hypertrophy in hypertension].
    Likars'ka sprava, 1992, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Hemodynamics; Humans; Hydrocortisone; Hyper

1992
Kallikrein-kinin,enkephalin, renin-aldosterone and catecholamine systems in the vanadate (as vanadyl)-induced arterial hypertension.
    Agents and actions. Supplements, 1992, Volume: 38 ( Pt 3)

    Topics: Aldosterone; Animals; Blood Pressure; Bradykinin; Bucladesine; Catecholamines; Diastole; Enkephalins

1992
Circadian rhythm of calcitonin gene-related peptide in uncomplicated essential hypertension.
    Journal of hypertension, 1992, Volume: 10, Issue:10

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Calcitonin Gene-Related Peptide; Case

1992
Acute effects of angiotensin-converting enzyme inhibitor on erythrocyte sodium ion transport in essential hypertension.
    Life sciences, 1992, Volume: 51, Issue:26

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Carrier Proteins; Cell Membrane Permeability; Erythro

1992
[The correlation of humoral factors with the indices of the phasic structure of the left ventricular cardiac cycle in hypertension patients].
    Terapevticheskii arkhiv, 1992, Volume: 64, Issue:9

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Chronic Disease; Combined Modality Therapy; Female;

1992
[The behavior of serum angiotensin-converting enzyme in normotensive subjects, in subjects with essential hypertension and in subjects with primary hyperaldosteronism on the orthostatic test].
    Minerva cardioangiologica, 1992, Volume: 40, Issue:12

    Topics: Adult; Aldosterone; Bed Rest; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; P

1992
Effects of dietary magnesium supplementation on diurnal variations of blood pressure and plasma Na+, K(+)-ATPase activity in essential hypertension.
    Japanese heart journal, 1992, Volume: 33, Issue:6

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Circadian Rhythm; Female; Humans; Hypertension; Magnesium;

1992
Effect of manidipine on cardiac hypertrophy and coronary circulation in DOCA/salt hypertensive rats.
    Blood pressure. Supplement, 1992, Volume: 3

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Coronary Circulation; C

1992
Reduction of left ventricular hypertrophy after longterm antihypertensive treatment with doxazosin.
    Journal of human hypertension, 1992, Volume: 6, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Cardiomeg

1992
Primary aldosteronism: hypertension with a genetic basis.
    Lancet (London, England), 1992, Jul-18, Volume: 340, Issue:8812

    Topics: Adrenocorticotropic Hormone; Aldosterone; Humans; Hyperaldosteronism; Hypertension

1992
[Effect of nifedipine treatment on the renin-aldosterone system and secretion of cortisol and growth hormone in patients with essential hypertension].
    Endokrynologia Polska, 1991, Volume: 42, Issue:3

    Topics: Adult; Aldosterone; Female; Growth Hormone; Humans; Hydrocortisone; Hypertension; Male; Middle Aged;

1991
Hemodynamic and endocrine changes associated with hypotensive action of amosulalol in essential hypertension.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:1

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Cardiac Output; Ethanolamines; Female;

1992
Atrial natriuretic factor in essential hypertension: echocardiographic and humoral correlates.
    Clinical cardiology, 1992, Volume: 15, Issue:5

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Echocardiography; Female; Humans; Hypertension; Male;

1992
Effect of a reduction in sodium intake on cold-induced elevation of blood pressure in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1992, Volume: 200, Issue:4

    Topics: Acclimatization; Aldosterone; Animals; Blood Pressure; Body Weight; Cardiomegaly; Cold Temperature;

1992
[Diurnal variation of blood pressure in salt-responder].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Circadian Rhythm; Female; Heart Rate;

1992
Atrial and brain natriuretic peptides: secretion during exercise in patients with essential hypertension and modulation by acute angiotensin-converting enzyme inhibition.
    Clinical and experimental pharmacology & physiology, 1992, Volume: 19, Issue:3

    Topics: Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood Pressu

1992
The influence of age on renal function and renin and aldosterone responses to sodium-volume expansion and contraction in normotensive and mildly hypertensive humans.
    American journal of hypertension, 1992, Volume: 5, Issue:8

    Topics: Adolescent; Adult; Aging; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Creatine; Cross-Se

1992
Zonal distribution and regulation of adrenal renin in a transgenic model of hypertension in the rat.
    Endocrinology, 1992, Volume: 131, Issue:4

    Topics: Adrenal Glands; Aldosterone; Animals; Animals, Genetically Modified; Cells, Cultured; Hypertension;

1992
Altered secretion of corticosteroids and prolactin in adrenal regeneration hypertensive rats.
    Endocrinologia japonica, 1992, Volume: 39, Issue:2

    Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Dopamine; Electrolytes; Hypertension; Male; Mi

1992
Abnormal norepinephrine and aldosterone responses to upright posture in nonmodulating hypertension.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 75, Issue:4

    Topics: Adult; Aldosterone; Analysis of Variance; Animals; Catecholamines; Female; Humans; Hypertension; In

1992
Elevation of plasma atrial natriuretic peptide occurs during adrenaline infusion in hypertensive but not normotensive subjects.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 1992, Volume: 2, Issue:5

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Epinephrine; Female; Heart Rate; Huma

1992
Response of plasma renin-angiotensin system to a single captopril administration in patients receiving long-term treatment with captopril.
    Clinical and experimental pharmacology & physiology, 1992, Volume: 19, Issue:10

    Topics: Aldosterone; Angiotensin II; Angiotensin III; Blood Pressure; Captopril; Drug Tolerance; Female; Hea

1992
[The dynamics of the concentration of atrial natriuretic factor depending on changes in the arterial pressure level in patients with arterial hypertension].
    Terapevticheskii arkhiv, 1992, Volume: 64, Issue:4

    Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Captopril; Chronic Disease; Humans; Hydrochl

1992
[The morphofunctional parallels in arterial hypertension in patients with chronic glomerulonephritis].
    Terapevticheskii arkhiv, 1992, Volume: 64, Issue:4

    Topics: Aldosterone; Biopsy; Chronic Disease; Glomerulonephritis; Glomerulonephritis, Membranoproliferative;

1992
[The morphofunctional parallels in arterial hypertension in patients with chronic glomerulonephritis].
    Terapevticheskii arkhiv, 1992, Volume: 64, Issue:6

    Topics: Adult; Aldosterone; Chronic Disease; Glomerulonephritis; Glomerulonephritis, Membranoproliferative;

1992
Non-modulation as an intermediate phenotype in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 20, Issue:6

    Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged;

1992
Renin-angiotensin-aldosterone system and thromboxane A2/prostacyclin in normotensive and hypertensive black Zimbabweans.
    Ethnicity & disease, 1992,Winter, Volume: 2, Issue:1

    Topics: Adult; Aldosterone; Black People; Epoprostenol; Evaluation Studies as Topic; Humans; Hypertension; M

1992
[Functional state of the adrenals in various forms of arterial hypertension].
    Arkhiv patologii, 1992, Volume: 54, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Cushing Syndrome; Huma

1992
[Changes in the humoral systems in juvenile arterial hypertension and their correction by using nifedipine and anaprilin].
    Likars'ka sprava, 1992, Issue:8

    Topics: Adolescent; Aldosterone; Angiotensin II; Blood Pressure; Drug Evaluation; Humans; Hypertension; Nife

1992
23Na NMR evaluation of human erythrocytes Na+/K+/CL-cotransport. A study in elderly hypertensives.
    Cellular and molecular biology (Noisy-le-Grand, France), 1992, Volume: 38, Issue:8

    Topics: Aged; Aldosterone; Blood Pressure; Carrier Proteins; Cholesterol; Creatinine; Erythrocytes; Humans;

1992
[Cardiac and renal sodium-modulating hormones in juvenile arterial hypertension. The physiopathological aspects and therapeutic results of a trial at the Policlinico Militare Celio in Rome].
    La Clinica terapeutica, 1992, Volume: 141, Issue:12

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Heart; Hospitals, Military; Humans; H

1992
Renin and aldosterone levels and hypertension following envenomation in humans by the yellow scorpion Leiurus quinquestriatus.
    Toxicon : official journal of the International Society on Toxinology, 1992, Volume: 30, Issue:7

    Topics: Adult; Aldosterone; Animals; Child; Child, Preschool; Humans; Hypertension; Infant; Middle Aged; Ren

1992
[Dopamine mechanisms in salt-responsive hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl

    Topics: Aldosterone; Catecholamines; Dopamine; Humans; Hypertension; Renin; Sodium, Dietary

1992
[Pathophysiology of normotensive subjects with a family history of hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl

    Topics: Adult; Aldosterone; Blood Pressure; Cell Membrane; Electrolytes; Humans; Hypertension; Kidney; Middl

1992
[Disease models of steroid-induced hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl

    Topics: Aldosterone; Animals; Corticosterone; Cushing Syndrome; Desoxycorticosterone; Dexamethasone; Disease

1992
Adrenal and circulating renin-angiotensin system in stroke-prone hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 20, Issue:3

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Cerebrovascular Disorders; Concanavalin A; Enz

1992
Concurrence of primary aldosteronism and renal artery stenosis.
    Clinical and experimental pharmacology & physiology, 1992, Volume: 19, Issue:5

    Topics: Adrenal Cortex; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renal Arte

1992
Renin-aldosterone relationships in pregnancy-induced hypertension.
    American journal of hypertension, 1992, Volume: 5, Issue:6 Pt 1

    Topics: Aldosterone; Female; Humans; Hypertension; Osmolar Concentration; Pregnancy; Pregnancy Complications

1992
The hypertensinogenic activity of 18,19-dihydroxycorticosterone in adrenalectomized rats.
    American journal of hypertension, 1992, Volume: 5, Issue:6 Pt 1

    Topics: 18-Hydroxycorticosterone; Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Blood Pressure; Drug

1992
Weight reduction decreases the circulating concentration of the N-terminus of the ANF prohormone.
    The American journal of the medical sciences, 1992, Volume: 303, Issue:1

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Diet, Reducing; Female; Humans;

1992
Importance of atrial natriuretic hormone in an exaggerated natriuresis during acute sodium load in primary aldosteronism.
    Acta endocrinologica, 1992, Volume: 126, Issue:1

    Topics: Aldosterone; Atrial Natriuretic Factor; Dopamine; Glomerular Filtration Rate; Humans; Hyperaldostero

1992
Endocrine sodium and volume regulation in familial hyperkalemia with hypertension.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Family; Female; Humans; Hydrochloroth

1992
[Study on uric acid metabolism in patients with primary aldosteronism].
    Nihon Naibunpi Gakkai zasshi, 1992, Jan-20, Volume: 68, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Female; Humans; Hyperaldosteron

1992
Hypertension during reduction of long-term steroid therapy in young subjects with asthma.
    The Journal of allergy and clinical immunology, 1992, Volume: 89, Issue:4

    Topics: Adolescent; Adrenal Cortex Hormones; Aldosterone; Asthma; Child; Female; Follow-Up Studies; Humans;

1992
Determination of urinary 18-hydroxycortisol in the diagnosis of primary aldosteronism.
    Journal of endocrinological investigation, 1992, Volume: 15, Issue:1

    Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Diagnosis,

1992
Aldosterone metabolism in the isolated perfused liver of R and S hypertension-prone Dahl rats.
    The American journal of physiology, 1992, Volume: 262, Issue:4 Pt 1

    Topics: Aldosterone; Animals; Bile; Chromatography, High Pressure Liquid; Hypertension; In Vitro Techniques;

1992
Increased systemic and renal vascular sensitivity to angiotensin II in normotensive men with positive family histories of hypertension.
    American journal of hypertension, 1992, Volume: 5, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Glomerular Filtration Rate; Heart R

1992
Metabolic cardiovascular risk factors and the renin-aldosterone system in essential hypertension.
    Journal of human hypertension, 1992, Volume: 6, Issue:1

    Topics: Adult; Aldosterone; Body Mass Index; Cardiovascular Diseases; Cholesterol, HDL; Creatine; Female; Gl

1992
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 24-1992. A 52-year-old man with hypertension, hypokalemia, and an adrenal mass.
    The New England journal of medicine, 1992, Jun-11, Volume: 326, Issue:24

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemi

1992
Vascular responsiveness in rats resistant to aldosterone-salt hypertension.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 20, Issue:1

    Topics: Aldosterone; Animals; Blood Vessels; Carotid Arteries; Disease Susceptibility; Hypertension; Male; R

1992
Adrenocorticosteroid excretion in salt-sensitive and salt-resistant spontaneously hypertensive rats.
    Steroids, 1992, Volume: 57, Issue:2

    Topics: Aldosterone; Animals; Blood Pressure; Chromatography, Thin Layer; Corticosterone; Desoxycorticostero

1992
First dose hypotension after captopril; can it be predicted? A study of 240 patients.
    Journal of human hypertension, 1992, Volume: 6, Issue:3

    Topics: Aldosterone; Captopril; Diastole; Forecasting; Humans; Hypertension; Hypotension; Prevalence; Prospe

1992
Enalapril versus combined enalapril and nadolol treatment: effects on blood pressure, heart rate, humoral variables, and plasma potassium at rest and during exercise in hypertensive patients.
    Cardiovascular drugs and therapy, 1992, Volume: 6, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Combined Modality Therapy; Enalapril; Female; Heart Rate; Hemody

1992
[Does the captopril test improve the diagnosis of primary hyperaldosteronism?].
    Deutsche medizinische Wochenschrift (1946), 1992, Jul-31, Volume: 117, Issue:31-32

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Pressure; Captopril; Diagnosis, Differen

1992
Diagnostic approach to patients with primary hyperaldosteronism.
    Acta clinica Belgica, 1991, Volume: 46, Issue:2

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertens

1991
Sodium metabolism in offspring of hypertensive parents.
    Biochemical medicine and metabolic biology, 1991, Volume: 45, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Child; Erythrocytes; Female; Humans; Hypertension; Male; Reference V

1991
[The significance of atrial natriuretic polypeptide in the cause of essential hypertension].
    Nihon Naibunpi Gakkai zasshi, 1991, Jul-20, Volume: 67, Issue:7

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Cyclic GMP; Dopamin

1991
Plasma and tissue kallikrein-kinin systems during acute administration of frusemide in normotensive and hypertensive humans.
    Clinical science (London, England : 1979), 1991, Volume: 81, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Dinoprostone; Electrolytes; Female

1991
Influence of betaxolol on renal function and atrial natriuretic peptide in essential hypertension.
    Journal of hypertension, 1991, Volume: 9, Issue:9

    Topics: Adolescent; Adult; Aldosterone; Atrial Natriuretic Factor; Betaxolol; Exercise Test; Female; Furosem

1991
Atrial natriuretic peptide in patients with essential hypertension. Hemodynamic, renal, and hormonal responses.
    American journal of hypertension, 1991, Volume: 4, Issue:11

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cardiac Output; Cyclic GMP; Glomerula

1991
Altered phospholipase activities related to alpha 1-adrenergic receptor supersensitivity of aortas from aldosterone-salt hypertensive rats.
    Advances in experimental medicine and biology, 1991, Volume: 308

    Topics: Aldosterone; Animals; Aorta; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nore

1991
Distinct plasma atrial natriuretic factor, renin and aldosterone responses to prolonged high-salt intake in hypertensive and normotensive rats.
    Journal of hypertension, 1991, Volume: 9, Issue:3

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Guanylate Cyclase; Homeostasis; Hypertension; Male;

1991
Remodeling of the rat right and left ventricles in experimental hypertension.
    Circulation research, 1990, Volume: 67, Issue:6

    Topics: Aldosterone; Angiotensin II; Animals; Cardiomegaly; Collagen; Fibrosis; Heart Ventricles; Hemodynami

1990
Body sodium in normal subjects predisposed to hypertension.
    Journal of cardiovascular pharmacology, 1990, Volume: 16 Suppl 7

    Topics: Aldosterone; Blood Pressure; Body Weight; Creatinine; Diet; Heart Rate; Humans; Hypertension; Male;

1990
The diurnal rhythm of plasma potassium: relationship to diuretic therapy.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:5

    Topics: Adult; Aldosterone; Amiloride; Animals; Blood Pressure; Circadian Rhythm; Cricetinae; Diuretics; Ele

1991
Regression of cardiovascular structural changes after long-term antihypertensive treatment with the calcium antagonist nitrendipine.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 5

    Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Echocardiography; Female; Heart Rate; Hemodynami

1991
Renin-angiotensin-aldosterone system in normal and hypertensive pregnancy. Response to postural stimuli.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:2 Suppl

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Posture; Pregnancy; Pr

1992
Dipyridamole decreases circulating renin-angiotensin system activity in hypertensive patients.
    American journal of hypertension, 1992, Volume: 5, Issue:1

    Topics: Adenosine; Administration, Oral; Adult; Aldosterone; Blood Pressure; Creatine; Dipyridamole; Female;

1992
Acute effect of erythropoietin on plasma renin activity and aldosterone levels in end-stage renal disease.
    Nephron, 1992, Volume: 60, Issue:1

    Topics: Aldosterone; Blood Pressure; Erythropoietin; Humans; Hypertension; Kidney Failure, Chronic; Renin; V

1992
Effects of angiotensin subtype 1 and subtype 2 receptor antagonists in normotensive versus hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 18, Issue:6

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Comp

1991
[The somatotype, blood hormone content and the threshold of taste sensitivity to table salt in young people with arterial hypertension].
    Terapevticheskii arkhiv, 1991, Volume: 63, Issue:9

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Growth Hormone; Hormones; Humans; Hypertension; Insu

1991
[The specificity of the hypotensive effect of calcium antagonists in hypertension].
    Terapevticheskii arkhiv, 1991, Volume: 63, Issue:9

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Calcium; Calcium Channel Blockers

1991
Sustained effects of biofeedback-assisted relaxation therapy in essential hypertension.
    Biofeedback and self-regulation, 1991, Volume: 16, Issue:4

    Topics: Adult; Aldosterone; Analysis of Variance; Anxiety; Biofeedback, Psychology; Blood Pressure; Humans;

1991
Effect of chronic treatment with clonidine and spironolactone on cold-induced elevation of blood pressure.
    Pharmacology, 1991, Volume: 43, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Clonidine; Cold Temperature; Drin

1991
Daily profiles of aldosterone levels during normal, high and low sodium intake in patients with essential hypertension.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1991, Volume: 23, Issue:12

    Topics: Adult; Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Periodicity; Renin; Sodium, Dieta

1991
Effects of cicletanine on vasoactive systems in conscious sinoaortic-denervated dogs.
    Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:8

    Topics: Aldosterone; Amino Acid Sequence; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; C

1991
Influence of nonhemodynamic factors on the microcirculation in moderate arterial essential hypertension.
    American journal of hypertension, 1991, Volume: 4, Issue:11

    Topics: Aldosterone; Blood Pressure; Hemodynamics; Humans; Hypertension; Microcirculation; Middle Aged; Nore

1991
Hyperfiltration and calcium metabolism in essential hypertension.
    American journal of hypertension, 1991, Volume: 4, Issue:12 Pt 1

    Topics: Adult; Aldosterone; Blood Pressure; Calcitriol; Calcium; Creatine; Female; Glomerular Filtration Rat

1991
[Aldosteroma (Conn's syndrome)].
    Kardiologiia, 1991, Volume: 31, Issue:12

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adult; Aldosterone; Diagnosis, Differential; Fema

1991
Arterial structural changes and pressor responsiveness to noradrenaline.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Adult; Aldosterone; Arteries; Blood Pressure; Forearm; Humans; Hypertension; Middle Aged; Norepineph

1991
Plasma endothelin-1,2 levels in mild and severe hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Endothelins; Humans; Hypertension; Middle Aged; Renin

1991
Time-course of changes in intracellular cations and blood pressure with salt loading in patients with essential hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Aldosterone; Blood Pressure; Calcium; Cations; Erythrocytes; Female; Hematocrit; Humans; Hypertensio

1991
[The level of plasma renin and plasma aldosterone activity in normotensive women and in pregnancy-induced arterial hypertension in a group of women from Cameroon].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1991, Volume: 20, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Cameroon; Female; Humans; Hypertension; Pregnancy; Pregnancy Com

1991
Elevation of plasma endothelin associated with systemic hypertension in humans following orthotopic liver transplantation.
    Transplantation, 1991, Volume: 51, Issue:3

    Topics: Aldosterone; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Endothelins; Female; Humans; Hyp

1991
Abnormal hormonal and renal responses to saline load in hypertensive patients with parental history of cardiovascular accidents.
    Circulation, 1991, Volume: 84, Issue:1

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cerebrovascular Disorders; Family Hea

1991
[Endothelin in arterial hypertension].
    Terapevticheskii arkhiv, 1991, Volume: 63, Issue:4

    Topics: Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Endothelins; Heart Failure; Humans; Hyperten

1991
[Atrial natriuretic factor in patients with hypertension].
    Kardiologiia, 1991, Volume: 31, Issue:3

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Hemodynamics; Humans; Hypertension; Natriuresis; Reni

1991
[Relation between traditional Chinese medicine differential types and plasma levels of renin, angiotension II, aldosterone, atrial natriuretic factor in patients with essential hypertension].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1991, Volume: 11, Issue:5

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Female; Humans; Hypertension; M

1991
Dissociation of plasma atrial natriuretic peptide responses to upright posture and furosemide administration in patients with normal-, low renin essential hypertension and primary aldosteronism.
    Clinical and experimental hypertension. Part A, Theory and practice, 1991, Volume: 13, Issue:3

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Furosemide; Humans; Hyperaldosteronism; Hypertension;

1991
Influence of the arterial blood pressure and nonhemodynamic factors on left ventricular hypertrophy in moderate essential hypertension.
    The American journal of cardiology, 1991, Oct-01, Volume: 68, Issue:9

    Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Determination; Cardiomegaly; Epinephrine; Female;

1991
Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneously hypertensive rats.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:6

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Biomarkers; Blood Pres

1991
Plasma concentrations of atrial natriuretic hormone in acromegaly: relationship to hypertension.
    Acta endocrinologica, 1991, Volume: 125, Issue:3

    Topics: Acromegaly; Adult; Aldosterone; Analysis of Variance; Atrial Natriuretic Factor; Blood Pressure; Fem

1991
Plasma atrial natriuretic peptide and its relation to the renin-angiotensin-aldosterone system in patients with chronic renal failure.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1991, Volume: 6, Issue:8

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Humans; Hypertension; Kidney Failure,

1991
Calcium metabolism in elderly hypertensive patients: possible participation of exaggerated sodium, calcium and phosphate excretion.
    Clinical and experimental pharmacology & physiology, 1991, Volume: 18, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Calcitriol;

1991
Therapeutic response may be predicted by some clinical parameters in essential hypertensive patients.
    Journal of human hypertension, 1991, Volume: 5, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Antihypertensive Agents; Blood Pressure; Cardiomegaly;

1991
Atrial natriuretic peptide and plasma volume in pregnancy-induced hypertension.
    American journal of hypertension, 1991, Volume: 4, Issue:11

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Volume; Capillary Permeability; Female; Humans;

1991
The syndrome of hypertension and hyperkalemia with normal GFR (Gordon's syndrome): is there increased proximal sodium reabsorption?
    Clinical and investigative medicine. Medecine clinique et experimentale, 1991, Volume: 14, Issue:6

    Topics: Absorption; Adult; Aldosterone; Atrial Natriuretic Factor; Female; Glomerular Filtration Rate; Human

1991
Relationship between parathyroid hormone and left ventricular mass in moderate essential hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Aldosterone; Blood Pressure; Cardiomegaly; Epinephrine; Female; Humans; Hypertension; Male; Middle A

1991
Impairment of atrial natriuretic factor response to acute saline load in hypertensives with family history of cardiovascular accidents.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Cerebrovascular Disorders; Female; Humans; Hypertensi

1991
Plasma sodium-potassium ATPase inhibition activity in low- and normal-renin hypertension.
    American journal of hypertension, 1991, Volume: 4, Issue:1 Pt 1

    Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Longitudinal Studies; Male; Norepi

1991
Resting and volume-stimulated circulating atrial natriuretic peptide in young normotensive men with positive family histories of hypertension.
    Journal of hypertension, 1991, Volume: 9, Issue:2

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Body Mass Index; Central Venous Press

1991
Platelet-free calcium and vascular calcium uptake in ethanol-induced hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 18, Issue:1

    Topics: Administration, Oral; Aldosterone; Animals; Aorta; Blood Platelets; Blood Pressure; Body Weight; Cal

1991
[Corticoid secretion and patho-histological changes in the adrenal glands in hypertension].
    Sovetskaia meditsina, 1991, Issue:1

    Topics: 11-Hydroxycorticosteroids; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Atrophy; Humans; Hydro

1991
[The renin-angiotensin-aldosterone system and arterial hypertension in patients with rheumatoid arthritis].
    Klinicheskaia meditsina, 1991, Volume: 69, Issue:2

    Topics: Adult; Aldosterone; Arthritis, Rheumatoid; Blood Pressure; Female; Humans; Hypertension; Middle Aged

1991
Angiotensin II mediates hyperadrenergic activity evoked by sodium restriction in essential hypertension.
    Life sciences, 1991, Volume: 49, Issue:13

    Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Diet, Sodium-Restrict

1991
[Arterial hypertension secondary to an aldosterone-producing adenoma (APA)].
    Anales de medicina interna (Madrid, Spain : 1984), 1991, Volume: 8, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension; Male; Middle Aged

1991
Effect of inhibition of converting enzyme on renal hemodynamics and sodium management in polycystic kidney disease.
    Mayo Clinic proceedings, 1991, Volume: 66, Issue:10

    Topics: Adult; Aldosterone; Blood Pressure; Enalapril; Erythrocytes; Female; Genes, Dominant; Glomerular Fil

1991
Licorice-induced hypermineralocorticoidism.
    The New England journal of medicine, 1991, Oct-24, Volume: 325, Issue:17

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aged; Aldosterone; Desoxycorticosterone; Foodborne Diseases;

1991
Effect of chronic dietary treatment with L-tryptophan on the development of cold-induced hypertension in rats.
    Pharmacology, 1991, Volume: 42, Issue:6

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Catecholamines; Cold Temperature; Diet; Hypert

1991
Historical reflections on hypertension.
    Primary care, 1991, Volume: 18, Issue:3

    Topics: Aldosterone; Auscultation; Blood Pressure Determination; Heart Sounds; History, 18th Century; Histor

1991
Sexual function and neuropeptide Y levels in selected brain regions in male spontaneously hypertensive rats.
    The American journal of physiology, 1991, Volume: 261, Issue:5 Pt 2

    Topics: Aldosterone; Analysis of Variance; Animals; Blood Pressure; Body Weight; Brain Chemistry; Copulation

1991
Angiotensin-converting enzyme inhibitor and anemia in a patient undergoing hemodialysis.
    Nephron, 1991, Volume: 59, Issue:2

    Topics: Aldosterone; Anemia; Blood Pressure; Enalapril; Erythropoietin; Hematocrit; Humans; Hypertension; Ki

1991
Systemic and renal effects of a new angiotensin converting enzyme inhibitor, benazepril, in essential hypertension.
    Journal of hypertension, 1990, Volume: 8, Issue:11

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Drug Evaluation; Electro

1990
Infradian, notably circannual, cardiovascular variation gauging effect of intrauterine exposure to beta-adrenergic agonists.
    Progress in clinical and biological research, 1990, Volume: 341A

    Topics: Adrenergic beta-Agonists; Aldosterone; Blood Pressure; Cardiovascular Physiological Phenomena; Cardi

1990
Captopril attenuates reflex adrenergic response in essential hypertension.
    Life sciences, 1991, Volume: 48, Issue:2

    Topics: Administration, Oral; Adult; Aldosterone; Blood Pressure; Captopril; Female; Hemodynamics; Humans; H

1991
Effect of a new mineralocorticoid antagonist mespirenone on aldosterone-induced hypertension.
    The American journal of physiology, 1991, Volume: 260, Issue:2 Pt 1

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Hypertension; Male; Mineralocorticoid Receptor An

1991
Temporal relationship between the decrease in arterial pressure and sodium retention in conscious spontaneously hypertensive rats with carbon tetrachloride-induced cirrhosis.
    Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Carbon Tetrachloride; Creatinine; Hypertension; Liver Cirrhosi

1991
Renal hemodynamics and the renin-angiotensin-aldosterone system in normotensive subjects with hypertensive and normotensive parents.
    The New England journal of medicine, 1991, May-09, Volume: 324, Issue:19

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Child; Female; Hemodynamics; Humans;

1991
Feasibility of outpatient electrolyte balance studies.
    Journal of the American College of Nutrition, 1991, Volume: 10, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin I; Creatinine; Feasibility Studies; Female; Humans; Hypertensi

1991
Effect of high calcium diet on the development of high blood pressure in intact spontaneously hypertensive rats and in adrenalectomized spontaneously hypertensive rats treated with aldosterone.
    Steroids, 1991, Volume: 56, Issue:3

    Topics: Adrenalectomy; Aldosterone; Animals; Body Weight; Calcium; Diet; Hypertension; Male; Rats; Rats, Inb

1991
Antihypertensive effects of an aromatase inhibitor in inbred salt-sensitive rats.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:6 Pt 1

    Topics: Aldosterone; Androstenedione; Animals; Antihypertensive Agents; Aromatase Inhibitors; Cortisone; Des

1991
[The correlation of the indices of humoral immunity and of the activity of the renin-angiotensin-aldosterone system in hypertensive patients].
    Terapevticheskii arkhiv, 1991, Volume: 63, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Antibody Formation; Disease Susceptibility; Humans; Hypertension

1991
Increased production of angiotensin II in the adrenal gland of stroke-prone spontaneously hypertensive rats with malignant hypertension.
    Biochemical and biophysical research communications, 1991, Jul-15, Volume: 178, Issue:1

    Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin I; Angiotensin II; Animals; Cerebrovascular Disorder

1991
Inappropriate elevation of the aldosterone/plasma renin activity ratio in hypertensive patients with increases of 11-deoxycorticosterone and 18-hydroxy-11-deoxycorticosterone: a subtype of essential hypertension?
    Cardiology, 1991, Volume: 78, Issue:2

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Glands; Adrenocortical Hyperfunction; Adult; Aged; Aldostero

1991
Effects of slow-release nifedipine on water-sodium, uric acid, and calcium metabolism, and on aldosterone secretion in patients with essential hypertension.
    Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 5

    Topics: Aldosterone; Angiotensin II; Calcium; Delayed-Action Preparations; Humans; Hypertension; Nifedipine;

1990
Hyperkalemia and hypertension: is this a "chloride-shunt" disorder?
    Clinical and investigative medicine. Medecine clinique et experimentale, 1990, Volume: 13, Issue:6

    Topics: Acidosis; Adolescent; Aldosterone; Chlorides; Diuretics; Female; Humans; Hyperkalemia; Hypertension;

1990
Preventive effect of angiotensin I on weight reduction in the adrenal glands of DOCA/salt hypertensive rats.
    Endocrinologia japonica, 1990, Volume: 37, Issue:4

    Topics: Adrenal Glands; Aldosterone; Angiotensin I; Animals; Blood Pressure; Body Weight; Corticosterone; De

1990
[Circadian rhythm of the renin-angiotensin-aldosterone system in the normal state and in pathology].
    Klinicheskaia meditsina, 1990, Volume: 68, Issue:8

    Topics: Aldosterone; Angiotensin III; Circadian Rhythm; Humans; Hyperaldosteronism; Hypertension; Reference

1990
[Diurnal fluctuations of plasma renin activity and aldosterone level in patients with arterial hypertension].
    Kardiologiia, 1990, Volume: 30, Issue:12

    Topics: Aldosterone; Blood Pressure; Chronic Disease; Circadian Rhythm; Humans; Hypertension; Hypertension,

1990
Long-term medical management of aldosterone-producing adenoma.
    Southern medical journal, 1990, Volume: 83, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Benzothiadiazines; Combined Modality Therapy; Diureti

1990
[The effect of clonidine on humoral factors in patients with arterial hypertension].
    Casopis lekaru ceskych, 1990, Mar-09, Volume: 129, Issue:10

    Topics: Adrenal Gland Neoplasms; Aldosterone; Atrial Natriuretic Factor; Catecholamines; Clonidine; Diagnosi

1990
Plasma atrial natriuretic factor levels during normal pregnancy and pregnancy complicated by diabetes mellitus and hypertension.
    Journal of human hypertension, 1990, Volume: 4, Issue:1

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Female; Humans; Hypertension; Pregnancy; Pregnancy Co

1990
Vasoactive humoral systems and sodium transport in erythrocytes of normotensive offsprings of essential hypertensive subjects.
    Physiologia Bohemoslovaca, 1990, Volume: 39, Issue:1

    Topics: Adult; Aldosterone; Biological Transport; Dinoprost; Erythrocytes; Furosemide; Humans; Hypertension;

1990
Pattern of peripheral venous response to volume expansion in borderline systemic hypertension.
    The American journal of cardiology, 1990, Sep-01, Volume: 66, Issue:5

    Topics: Adolescent; Adult; Aldosterone; ATPase Inhibitory Protein; Atrial Natriuretic Factor; Female; Forear

1990
Plasma atrial natriuretic peptide in young normotensive subjects with a family history of hypertension and in young hypertensive patients.
    American journal of hypertension, 1990, Volume: 3, Issue:10

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure Determination; Evaluation Studies as T

1990
Long term reduction in sodium balance: possible additional mechanism whereby nifedipine lowers blood pressure.
    BMJ (Clinical research ed.), 1990, Sep-22, Volume: 301, Issue:6752

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Female; Humans; Hy

1990
[Mutual interaction of the renin-angiotensin system and the atrial natriuretic factor in the renal response to acute volume loading].
    Vnitrni lekarstvi, 1990, Volume: 36, Issue:7

    Topics: Aldosterone; Ascites; Atrial Natriuretic Factor; Extracellular Space; Humans; Hypertension; Kidney;

1990
Flight influence on the plasma level of renin-angiotensin-aldosterone system and atrial natriuretic peptide.
    Aviation, space, and environmental medicine, 1990, Volume: 61, Issue:11

    Topics: Adult; Aerospace Medicine; Aldosterone; Angiotensin I; Angiotensin II; Atrial Natriuretic Factor; Hu

1990
Atrial natriuretic peptide in normal and low renin essential hypertension.
    Kidney international. Supplement, 1990, Volume: 30

    Topics: Aldosterone; Atrial Natriuretic Factor; Furosemide; Humans; Hypertension; Posture; Renin; Renin-Angi

1990
[Captopril and hypertensive cardiopathy : therapeutic effects and hormonal changes].
    Cardiologia (Rome, Italy), 1990, Volume: 35, Issue:6

    Topics: Aged; Aldosterone; Atrial Natriuretic Factor; Captopril; Female; Heart Failure; Humans; Hypertension

1990
New aspects of mineralocorticoid hypertension.
    Hormone research, 1990, Volume: 34, Issue:3-4

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenal Glands; Aldosterone; Atrial Natri

1990
Prolonged low dose infusion of atrial natriuretic factor in essential hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1990, Volume: 12, Issue:1

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Electrolytes; Heart Rate;

1990
Effects of aldosterone on intralymphocytic sodium and potassium in patients with essential hypertension.
    Klinische Wochenschrift, 1990, Jan-19, Volume: 68, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Lymphocytes; Male; Mid

1990
Circadian rhythms of atrial natriuretic peptide, renin, aldosterone, cortisol, blood pressure and heart rate in normal and hypertensive subjects.
    Journal of hypertension, 1990, Volume: 8, Issue:1

    Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Circadian Rhythm; Female; Heart Rate; Humans

1990
[The significance of cGMP and dopamine receptor on the natriuretic and hypotensive activities of synthetic atrial natriuretic polypeptide in essential hypertension].
    Nihon Naibunpi Gakkai zasshi, 1990, Feb-20, Volume: 66, Issue:2

    Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Dopamine Antagonists; Humans; Hy

1990
[Effect of a beta 1-receptor blocker on the plasma level of atrial natriuretic peptide in patients with essential hypertension in the exercise test].
    Klinische Wochenschrift, 1990, May-04, Volume: 68, Issue:9

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Betaxolol; Blood Pressure; Cyclic GMP; Exercise Test;

1990
[Diagnosis of adrenal gland tumors].
    Vestnik khirurgii imeni I. I. Grekova, 1990, Volume: 144, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Androsterone; Cushing Syndrome; Diagnosis, Differenti

1990
Amiloride blocks the onset of ACTH-induced hypertension in the sheep.
    American journal of hypertension, 1990, Volume: 3, Issue:10

    Topics: Adrenocorticotropic Hormone; Aldosterone; Amiloride; Animals; Blood Pressure; Drug Administration Sc

1990
Hemodynamic and humoral effects of chronic antihypertensive treatment with fenquizone: importance of aldosterone response.
    Journal of clinical pharmacology, 1990, Volume: 30, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Chronic Disease; Diuretics; Female; Forearm; Heart Rate; Hemodyn

1990
[Processing of clinical tests for the diagnosis of hypertension].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1990, Jan-10, Volume: 79, Issue:1

    Topics: Aldosterone; Blood Urea Nitrogen; Diagnosis, Differential; Electrolytes; Hematologic Tests; Humans;

1990
Biochemical correction in the syndrome of hypertension and hyperkalaemia by severe dietary salt restriction suggests renin-aldosterone suppression critical in pathophysiology.
    Clinical and experimental pharmacology & physiology, 1990, Volume: 17, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Animals; Diet, Sodium-Restricted; Family Health; Humans; Hyperka

1990
Pharmacological evaluation of hydroxypropylcellulose-ethylcellulose microcapsules containing piretanide.
    Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:1

    Topics: Administration, Oral; Aldosterone; Animals; Blood Pressure; Body Weight; Cellulose; Diuretics; Drug

1990
Assessment of renin dependency of hypertension with a dipeptide renin inhibitor.
    Circulation, 1990, Volume: 81, Issue:6

    Topics: Adult; Aged; Aldosterone; Dipeptides; Dose-Response Relationship, Drug; Female; Humans; Hydrochlorot

1990
Physiological and immunopathological consequences of active immunization of spontaneously hypertensive and normotensive rats against murine renin.
    Circulation, 1990, Volume: 81, Issue:6

    Topics: Aldosterone; Angiotensinogen; Animals; Homeostasis; Hypertension; Immunization; Kidney; Male; Mice;

1990
Angiotensin-converting enzyme (ACE) inhibition. Therapeutic option for diabetic hypertensive patients.
    Drugs, 1990, Volume: 39 Suppl 2

    Topics: Adult; Aldosterone; Diabetes Mellitus, Type 2; Enalapril; Female; Humans; Hypertension; Male; Middle

1990
Beneficial effects of angiotensin-converting enzyme inhibitor on renal function and glucose homeostasis in diabetics with hypertension.
    Nephron, 1990, Volume: 55 Suppl 1

    Topics: Aged; Aldosterone; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies;

1990
Relationship between plasma catecholamines and the renin-aldosterone system during exercise in normal and essential hypertensive subjects.
    Clinical and experimental hypertension. Part A, Theory and practice, 1990, Volume: 12, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Exercise; Exercise Test; Humans; Hypertension; M

1990
Acromegaly and hypertension: prevalence and relationship to the renin-angiotensin-aldosterone system.
    Klinische Wochenschrift, 1990, Jun-19, Volume: 68, Issue:12

    Topics: Acromegaly; Aldosterone; Blood Pressure; Cross-Sectional Studies; Female; Germany, West; Growth Horm

1990
The renin-angiotensin-aldosterone system and autosomal dominant polycystic kidney disease.
    The New England journal of medicine, 1990, Oct-18, Volume: 323, Issue:16

    Topics: Adult; Aldosterone; Blood Pressure; Clinical Protocols; Enalapril; Female; Humans; Hypertension; Mal

1990
[The malignant hypertension syndrome: incontrovertible and questionable truths].
    Terapevticheskii arkhiv, 1990, Volume: 62, Issue:6

    Topics: Aldosterone; Biopsy, Needle; Chronic Disease; Glomerulonephritis; Hemodynamics; Humans; Hydrocortiso

1990
Alterations in aldosterone secretion and metabolism in low renin hypertension.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 71, Issue:6

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Posture; Renin

1990
[Plasma mineralocorticoids--aldosterone and desoxycorticosterone-- in patients with"low-renin"arterial hypertension].
    Kardiologiia, 1990, Volume: 30, Issue:7

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Atrophy; Desoxycorticosterone; Humans; Hypera

1990
Salt sensitivity in hypertensive rats with angiotensin II administration.
    The American journal of physiology, 1990, Volume: 259, Issue:5 Pt 2

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Hypertension; Male; Rats; Rats, Inbred Strains

1990
Effects of renin inhibition in systemic hypertension.
    The American journal of cardiology, 1990, Dec-01, Volume: 66, Issue:19

    Topics: Adult; Aldosterone; Dipeptides; Epoprostenol; Female; Humans; Hypertension; Male; Middle Aged; Renin

1990
Serum aldosterone response to metoclopramide in normal subjects and acromegalic patients.
    Experimental and clinical endocrinology, 1990, Volume: 95, Issue:3

    Topics: Acromegaly; Adult; Aldosterone; Dopamine; Female; Humans; Hypertension; Injections, Intravenous; Mal

1990
Effects of altered dietary sodium intake on hormonal profiles in salt-sensitive hypertensive rats.
    The Journal of endocrinology, 1990, Volume: 127, Issue:2

    Topics: Aldosterone; Animals; Cortisone; Desoxycorticosterone; Diet; Hydroxycorticosteroids; Hypertension; M

1990
[Plasma renin activity and aldosterone in patients with essential hypertension].
    Vnitrni lekarstvi, 1990, Volume: 36, Issue:9

    Topics: Adolescent; Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin

1990
Calcium antagonists inhibit elevated potassium efflux from aorta of aldosterone-salt hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1990, Volume: 15, Issue:1

    Topics: Aldosterone; Animals; Aorta; Calcium; Calcium Channel Blockers; Diltiazem; Hypertension; In Vitro Te

1990
Prostanoids and aldosterone-induced mild experimental hypertension in rats.
    Hypertension (Dallas, Tex. : 1979), 1990, Volume: 15, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Animals; Blood Pressure; Hypertension; Indomethacin; Male

1990
Salt-sensitive blood pressure and exaggerated vascular reactivity in the hypertension of diabetes mellitus.
    The American journal of medicine, 1990, Volume: 88, Issue:3

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Diabetes Mellitus, Type 2; Diet, Sodium-Re

1990
Intracerebroventricular infusion of RU28318 blocks aldosterone-salt hypertension.
    The American journal of physiology, 1990, Volume: 258, Issue:3 Pt 1

    Topics: Aldosterone; Animals; Blood Pressure; Cerebral Ventricles; Hypertension; Infusions, Parenteral; Male

1990
Elevated K turnover in mesenteric arteries from aldosterone-salt hypertensive rats.
    Progress in clinical and biological research, 1990, Volume: 327

    Topics: Aldosterone; Animals; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Potassium; Rats;

1990
ICV infusion of corticosterone antagonizes ICV-aldosterone hypertension.
    The American journal of physiology, 1990, Volume: 258, Issue:4 Pt 1

    Topics: Aldosterone; Animals; Blood Pressure; Cerebral Ventricles; Corticosterone; Hypertension; Injections,

1990
Effects of antimineralocorticoid RU 26752 on steroid-induced hypertension in rats.
    The American journal of physiology, 1990, Volume: 258, Issue:5 Pt 1

    Topics: Aldosterone; Animals; Blood Pressure; Hypertension; Male; Nephrectomy; Rats; Rats, Inbred Strains; R

1990
Primary aldosteronism. Study of twenty-six operated cases.
    Urology, 1990, Volume: 35, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Female; Foll

1990
Effect of high calcium diet and nitrendipine on the development of high blood pressure in adrenalectomised spontaneously hypertensive rats treated with aldosterone.
    Journal of human hypertension, 1990, Volume: 4, Issue:2

    Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Calcium, Dietary; Hypertension; Male; Nitrendip

1990
A symposium: International update--the important role of aldosterone and aldosterone antagonism in cardiovascular medicine. Based on symposia held in Brussels, Belgium and Newport Beach, California.
    The American journal of cardiology, 1990, Jun-19, Volume: 65, Issue:23

    Topics: Aldosterone; Heart Diseases; Humans; Hypertension; Mineralocorticoid Receptor Antagonists

1990
Role of aldosterone in angiotensin II-induced hypertension in rats.
    The American journal of physiology, 1990, Volume: 259, Issue:1 Pt 2

    Topics: Aldosterone; Angiotensin II; Animals; Dose-Response Relationship, Drug; Hypertension; Infusions, Int

1990
Dopamine and nonmodulating hypertension.
    American journal of hypertension, 1990, Volume: 3, Issue:6 Pt 2

    Topics: Adrenal Glands; Aldosterone; Blood Pressure; Diet; Dopamine; Humans; Hypertension; Metoclopramide; P

1990
Localization of aldosterone-producing adenoma: venous sampling in primary aldosteronism.
    Endocrinologia japonica, 1990, Volume: 37, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Female; Humans; Hydrocortisone

1990
The effect of chronic guanfacine administration on high plasma vasopressin levels in essential hypertension.
    International journal of clinical pharmacology, therapy, and toxicology, 1990, Volume: 28, Issue:2

    Topics: Aldosterone; Blood Pressure; Female; Guanfacine; Guanidines; Humans; Hypertension; Male; Middle Aged

1990
Chronic effects of arotinolol (S-596) in spontaneously hypertensive rats.
    Journal of pharmacobio-dynamics, 1985, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Aldosterone; Animals; Blood Pressure; Body Weight; Heart Rate; Hyperten

1985
Aldosterone binding in isolated tubules. IV. Autoradiography along the nephron of the spontaneously hypertensive rat.
    The American journal of physiology, 1985, Volume: 249, Issue:1 Pt 2

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Autoradiography; Binding Sites; Female; Hyperte

1985
Why use angiotensin converting enzyme inhibitors to lower blood pressure?
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 4

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhib

1985
Ketanserin: a possible tool for studying the role of serotonin in hypertension.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 7

    Topics: Aldosterone; Blood Pressure; Female; Hemodynamics; Humans; Hypertension; Ketanserin; Male; Middle Ag

1985
Calcium metabolism and the renin-aldosterone system in essential hypertension.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 6

    Topics: Aldosterone; Blood Pressure; Calcium; Calcium Channel Blockers; Humans; Hypertension; Magnesium; Par

1985
Unusual association of hyperkalemia and hypertension.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:2

    Topics: Adult; Aldosterone; Bicarbonates; Erythrocytes; Female; Humans; Hyperkalemia; Hypertension; Ion Chan

1986
Cellular sodium transport in arterial wall--summary of studies by digital computer simulation.
    International journal of bio-medical computing, 1986, Volume: 18, Issue:2

    Topics: Aldosterone; Animals; Arteries; Biological Transport, Active; Computers; Extracellular Space; Hypert

1986
Changes in the pathophysiologic profile of blood pressure determinants during short-term enalapril administration.
    Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 1

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Dose-Response Relationship, Drug;

1986
Borderline hypertension and sodium sensitivity.
    Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 5

    Topics: Aldosterone; Blood Pressure; Cardiac Output; Electrocardiography; Humans; Hypertension; Microcircula

1986
Effects of an angiotensin-converting enzyme (ACE) inhibitor, SA446, on tissue ACE activity in normotensive, spontaneously hypertensive, and renal hypertensive rats.
    Journal of cardiovascular pharmacology, 1987, Volume: 9, Issue:3

    Topics: 3-Mercaptopropionic Acid; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypert

1987
Antihypertensive effects and pharmacokinetics of single and consecutive administration of doxazosin in patients with mild to moderate essential hypertension.
    Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Creatinine; Doxazosin; Electrolytes; Female; Hea

1987
Autometrically and automatically monitored, iatrogenous, inhalant-decongestant-associated high blood pressure quantified by rhythmometry.
    Progress in clinical and biological research, 1987, Volume: 227B

    Topics: Adult; Aldosterone; Blood Pressure; Blood Pressure Determination; Circadian Rhythm; Fluprednisolone;

1987
[Excess mineralocorticoid syndrome secondary to nasal sprays containing 9 alpha-fluoroprednisolone].
    Minerva medica, 1987, Sep-15, Volume: 78, Issue:17

    Topics: Aldosterone; Fluprednisolone; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Mineralocorticoi

1987
Antihypertensive, enzymatic, and hormonal activity of cilazapril, a new angiotensin-converting enzyme inhibitor in patients with mild to moderate essential hypertension.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:2

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cilazapril; F

1988
Nifedipine does not blunt the aldosterone and cardiovascular response to angiotensin II and potassium infusion in hypertensive patients.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:3

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Drug Interactions; Female; Heart Rate; Hem

1988
Long-term effect of tiapamil in essential hypertension.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:3

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Electrocardiography; Female; Hear

1988
Hormonal and renal responses to oral once-daily calcium entry blocker in normotensive and hypertensive persons.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Calcium Channel Blockers; Dopamine; Epinephrine; Female; Hemodyn

1988
Effects of different sodium intakes on the antihypertensive and renal effects of single oral doses of nifedipine in hypertensive patients.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10

    Topics: Administration, Oral; Adult; Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Furosemide;

1987
Vasoconstriction and hypersensitivity to vasoactive substances after acute volume expansion in dogs.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 12, Issue:1

    Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Volume; Cardiac Output; Dextr

1988
Altered chloride transport in arteries from aldosterone salt-hypertensive rats.
    Journal of hypertension, 1988, Volume: 6, Issue:7

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo

1988
Effects of ketanserin on peripheral vascular pressor mechanisms in essential hypertension.
    Journal of cardiovascular pharmacology, 1988, Volume: 11 Suppl 1

    Topics: Aldosterone; Blood Pressure; Extremities; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male

1988
Loop diuretics combined with an ACE inhibitor for treatment of hypertension: a study with furosemide, piretanide, and ramipril in spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 1989, Volume: 13 Suppl 3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Bridged

1989
Aldosterone, catecholamines, and CK-BB as biochemical markers in hypertensive intracerebral hemorrhage.
    Neurologia medico-chirurgica, 1989, Volume: 29, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Catecholamines; Cerebral Hemorrhage; Creatine Kinase; H

1989
Effect of angiotensin converting-enzyme inhibition on potassium-mediated aldosterone secretion in essential hypertension.
    Clinical science (London, England : 1979), 1985, Volume: 68, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Pota

1985
Abnormal glomerular and tubular function during angiotensin converting enzyme inhibition in renovascular hypertension evaluated by the lithium clearance method.
    European journal of clinical investigation, 1989, Volume: 19, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Glomerular Filtration Rate; H

1989
Short-term monotherapy with the potassium channel activator BRL 34915 on endocrine sodium regulation in essential hypertension.
    American journal of hypertension, 1989, Volume: 2, Issue:4

    Topics: Administration, Oral; Adult; Aldosterone; Atrial Natriuretic Factor; Benzopyrans; Blood Pressure; Cr

1989
Atrial natriuretic peptide and exaggerated natriuresis during acute hypertonic volume expansion in essential hypertension.
    Journal of hypertension, 1989, Volume: 7, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Volume; D

1989
[Atrial natriuretic factor: an epidemiological study. Preliminary results].
    La Clinica terapeutica, 1989, Mar-15, Volume: 128, Issue:5

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Epidemiologic Methods; Humans; Hypert

1989
[Humoral mechanisms in the pathogenesis of arterial hypertension with emphasis on the renin-angiotensin-aldosterone system and natriuretic substances].
    Vnitrni lekarstvi, 1989, Volume: 35, Issue:3

    Topics: Aldosterone; Atrial Natriuretic Factor; Humans; Hypertension; Natriuretic Agents; Renin-Angiotensin

1989
Hypoxic modulation of systolic blood pressure and urinary sodium excretion in spontaneously hypertensive rats after carotid body denervation.
    Physiologia Bohemoslovaca, 1989, Volume: 38, Issue:3

    Topics: Aldosterone; Animals; Blood Gas Analysis; Blood Pressure; Body Weight; Carotid Body; Hydrogen-Ion Co

1989
[Role of atrial natriuretic peptide in hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 47, Issue:9

    Topics: Aldosterone; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Depression, Chemical; Huma

1989
Weight reduction decreases atrial natriuretic factor and blood pressure in obese patients.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:12

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Electrolytes; Female; Heart Rat

1989
On the pathogenesis of arterial blood pressure elevation early in the course of diabetic nephropathy.
    Scandinavian journal of clinical and laboratory investigation, 1989, Volume: 49, Issue:6

    Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Atrial Natriuretic Factor; Diabetes Mellitus, Typ

1989
Effects of cilazapril on renal function and hormones in hypertensive patients with renal disease.
    The American journal of medicine, 1989, Dec-26, Volume: 87, Issue:6B

    Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cilazapril; Female; Gl

1989
Central and peripheral effects of the peptide ANF on renal function and blood pressure in hypertensive rats.
    The Journal of physiology, 1989, Volume: 418

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Heart Rate; Hypertension; Infusions

1989
ACTH effects on aldosterone, cortisol, and other steroids.
    Hospital practice (Office ed.), 1989, Jan-15, Volume: 24, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; AIDS-Related

1989
Prolonged converting enzyme inhibition in non-modulating hypertension.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 13, Issue:4

    Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diet, Sodium-

1989
The antihypertensive response to lisinopril: the effect of age in a predominantly black population.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Black

1989
Chronobiological evidence for an uncoupling of the Na,K-ATPase to aldosterone in normal renin hypertension.
    Enzyme, 1989, Volume: 41, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Erythrocyte Membrane; Female; Humans; Hypertension

1989
Effect of dietary sodium on the Na-K ATPase inhibitor in patients with essential hypertension.
    American journal of hypertension, 1989, Volume: 2, Issue:7

    Topics: Aldosterone; ATPase Inhibitory Protein; Biological Transport; Blood Proteins; Body Weight; Erythrocy

1989
An association between mineral metabolism and the renin-aldosterone system in human hypertension.
    Journal of human hypertension, 1989, Volume: 3, Issue:2

    Topics: Adult; Aldosterone; Calcium; Cyclic AMP; Female; Humans; Hypertension; Magnesium; Male; Middle Aged;

1989
Progesterone antagonizes development but not maintenance of ACTH-induced hypertension in sheep.
    Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:8

    Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure; Female; Hypertension; Infusions,

1989
Angiotensin-induced hypertension in the rat. Sympathetic nerve activity and prostaglandins.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 14, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Angiotensin II; Animals; Blood Pressure; Dinoprostone; Hy

1989
Endogenous digoxin-like immunoreactive factor and digitalis-like factor associated with the hypertension of patients receiving multiple alkylating agents as part of autologous bone marrow transplantation.
    Clinical science (London, England : 1979), 1989, Volume: 77, Issue:5

    Topics: Adult; Aldosterone; Alkylating Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Protein

1989
Enhanced slow-pressor response to angiotensin II in spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Captopril; Hypertension; Kidney; Muscle, Smoot

1989
Aldosterone, kallikrein, kininase I and II in normal and hypertension complicated pregnancy.
    Advances in experimental medicine and biology, 1989, Volume: 247B

    Topics: Aldosterone; Carboxypeptidases; Female; Humans; Hypertension; Kallikreins; Lysine Carboxypeptidase;

1989
Adrenocortical steroid requirements for initiation of ACTH-dependent hypertension in sheep.
    Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:10

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Ani

1989
Bopindolol: long-term effects on blood pressure, renal function, plasma renin activity, and plasma aldosterone in mild-to-moderate essential hypertension.
    Fundamental & clinical pharmacology, 1989, Volume: 3, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Blood Pressure; Electrolytes; Female; Heart R

1989
Hemodynamic and beta-adrenergic receptor adaptations during long-term beta-adrenoceptor blockade. Studies with acebutolol, atenolol, pindolol, and propranolol in hypertensive patients.
    Circulation, 1989, Volume: 80, Issue:4

    Topics: Adaptation, Physiological; Adrenergic beta-Antagonists; Adult; Aldosterone; Catecholamines; Hemodyna

1989
The effect of triple drug therapy on renal function in patients with essential hypertension.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:9

    Topics: Adrenergic beta-Antagonists; Aged; Aldosterone; Antihypertensive Agents; Atenolol; Betaxolol; Blood

1989
Comparison of dopamine and fenoldopam effects on renal blood flow and prostacyclin excretion in normal and essential hypertensive subjects.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 69, Issue:6

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adult; Aged; Aldosterone; Blood Pressure

1989
Effect of oral potassium on urinary kallikrein excretion in essential hypertension.
    Advances in experimental medicine and biology, 1989, Volume: 247B

    Topics: Administration, Oral; Adult; Aldosterone; Humans; Hypertension; Kallikreins; Middle Aged; Potassium;

1989
[Crisis of arterial hypertension in patients with primary aldosteronism].
    Kardiologiia, 1989, Volume: 29, Issue:11

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adult; Aldosterone;

1989
[The renin-angiotensin-aldosterone system in hypertension of hypothalamic origin].
    Klinicheskaia meditsina, 1989, Volume: 67, Issue:10

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Hypothalamic Diseases; Middle

1989
Glucocorticoid receptors and dissociation constant (Kd) are decreased in mononuclear leukocytes of spontaneously hypertensive rats (SHR-SP) as compared to normotensive Wistar-Kyoto rats (WKY).
    Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6

    Topics: 18-Hydroxycorticosterone; Aldosterone; Animals; Corticosterone; Female; Hypertension; Kinetics; Mono

1989
Regulation of cardiac output during aldosterone-induced hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6

    Topics: Aldosterone; Animals; Blood Pressure Monitors; Cardiac Output; Dogs; Hemodynamics; Hypertension; Inf

1989
Effects of nicardipine on blood pressure and renal function in elderly hypertensive patients with renal dysfunction.
    American heart journal, 1989, Volume: 117, Issue:1

    Topics: Aged; Aldosterone; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Cholesterol; Creatinine; Elec

1989
Blood pressure and serum calcium responses to altered sodium intake in high renin hypertension.
    American journal of hypertension, 1989, Volume: 2, Issue:3 Pt 1

    Topics: Adult; Aldosterone; Blood Pressure; Calcium; Female; Humans; Hypertension; Male; Norepinephrine; Ren

1989
Effect of transdermal clonidine on the endocrine responses to insulin-induced hypoglycemia in essential hypertension.
    Clinical pharmacology and therapeutics, 1989, Volume: 45, Issue:4

    Topics: Administration, Cutaneous; Adult; Aldosterone; Blood Glucose; Blood Pressure; Clonidine; Diabetes Co

1989
Urinary kallikrein excretion following chronic sinoaortic denervation in conscious dogs.
    Clinical and experimental hypertension. Part A, Theory and practice, 1989, Volume: 11, Issue:2

    Topics: Aldosterone; Animals; Blood Pressure; Carotid Sinus; Catecholamines; Chromatography, High Pressure L

1989
Hemodynamic and endocrine effects of acute and chronic administration of nifedipine.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:2

    Topics: Aldosterone; Arginine; Blood Pressure; Cardiac Output; Endocrine Glands; Female; Glucagon; Glycated

1989
Normotension with decreased plasma renin activity and low serum ionic calcium levels: a prehypertensive state?
    Southern medical journal, 1989, Volume: 82, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Calcium; Female; Humans; Hypertension; Magnesium; Male; Middle A

1989
Management of low-renin hypertension.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1989, Volume: 13, Issue:6 Suppl 1

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diuretics; Humans;

1989
Nadolol antihypertensive effect and disposition in young and elderly adults with mild to moderate essential hypertension.
    Clinical pharmacology and therapeutics, 1989, Volume: 46, Issue:1

    Topics: Adult; Aged; Aging; Aldosterone; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Hyper

1989
Effect of benazepril monotherapy in subjects with hypertension associated with renal dysfunction.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:7

    Topics: Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines;

1989
Relationships between renin, aldosterone, blood pressure and renal function in hypertensive insulin-dependent diabetes mellitus.
    Diabetes research and clinical practice, 1989, Aug-01, Volume: 7, Issue:2

    Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Neuropathies;

1989
[Effect of obzidan on hemodynamic indices and the renin and aldosterone levels of the blood plasma in patients with juvenile hypertension].
    Vrachebnoe delo, 1989, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Drug Evaluation; Drug Resistance; Hemodynamics; Humans; Hypertension

1989
[The use of digoxin, lasix and finoptin in treating circulatory failure in hypertension].
    Terapevticheskii arkhiv, 1989, Volume: 61, Issue:8

    Topics: Aged; Aldosterone; Digoxin; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Humans; Hy

1989
[Primary hyperaldosteronism without arterial hypertension].
    Deutsche medizinische Wochenschrift (1946), 1989, Dec-22, Volume: 114, Issue:51-52

    Topics: 18-Hydroxycorticosterone; Acidosis, Renal Tubular; Adenoma; Adrenal Gland Neoplasms; Adult; Aldoster

1989
The effects of aging on urinary kallikreins and other vasoactive substances in essential hypertension.
    Advances in experimental medicine and biology, 1989, Volume: 247B

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aldosterone; Blood Pressure; Dinoprostone; Female; Humans; Hy

1989
Urinary kallikrein excretion in neurogenic hypertension in the dogs: possible relationship between kallikrein excretion and catecholamines.
    Advances in experimental medicine and biology, 1989, Volume: 247B

    Topics: Aldosterone; Animals; Blood Pressure; Denervation; Dogs; Epinephrine; Female; Hypertension; Kallikre

1989
Do weak mineralocorticoids affect the pathogenesis of hypertension in Cushing's disease?
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6

    Topics: Adult; Aldosterone; Cushing Syndrome; Female; Humans; Hypertension; Male; Middle Aged; Mineralocorti

1989
Renin inhibition with A-64662: effect on blood pressure and hormonal response in man.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Dipeptides; Dose-Response Relationship, Drug; Drug Eval

1989
Effect of single-administration captopril on plasma and urinary vasopressin in normotensive subjects and patients with essential hypertension and primary aldosteronism.
    Japanese circulation journal, 1989, Volume: 53, Issue:12

    Topics: Adult; Aldosterone; Arginine Vasopressin; Captopril; Depression, Chemical; Female; Humans; Hyperaldo

1989
Cardiovascular regulatory functions in elderly patients with hypertension.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Blood Pressure; Cardiovascular System; Female; Heart; H

1989
Nisoldipine inhibition of sodium influx into aorta from aldosterone-salt-hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 13, Issue:6 Pt 2

    Topics: Aldosterone; Animals; Aorta; Calcium; Calcium Channel Blockers; Hydrogen; Hypertension; Ion Exchange

1989
The role of dopamine in nonmodulating hypertension.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 69, Issue:2

    Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Dopamine; Dose-Response

1989
Steroids during development of genetic hypertension in rats of Lyon strain.
    The American journal of physiology, 1989, Volume: 257, Issue:2 Pt 2

    Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Blood Pressure; Body Weight; Creatinine; Hypertension

1989
Internal desynchronization between circadian rhythms of plasma aldosterone and erythrocyte membrane-bound Na/K-ATPase.
    Progress in clinical and biological research, 1987, Volume: 227B

    Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Erythrocyte Membrane; Female; Humans; Hypertension

1987
New findings in apparent mineralocorticoid excess.
    Clinical endocrinology, 1987, Volume: 27, Issue:1

    Topics: Adrenocorticotropic Hormone; Aldosterone; Child; Child, Preschool; Cortisone; Female; Humans; Hydroc

1987
Hypertension during extracorporeal membrane oxygenation: cause, effect, and management.
    Surgery, 1987, Volume: 102, Issue:4

    Topics: Aldosterone; Cardiac Output; Catecholamines; Humans; Hypertension; Infant, Newborn; Oxygenators, Mem

1987
Pathogenesis of systemic hypertension and glomerular injury in the spontaneously hypertensive rat.
    The American journal of cardiology, 1987, Dec-14, Volume: 60, Issue:17

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Catecholamines; Glomerular Filtration Rate; Hyperte

1987
Arterial hypertension in acromegaly: altered dopaminergic control of aldosterone secretion.
    Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:11

    Topics: Acromegaly; Adrenocorticotropic Hormone; Adult; Aldosterone; Cosyntropin; Female; Humans; Hypertensi

1987
Effect of atrial natriuretic factor on aldosterone and its precursor steroid production in adrenal zona glomerulosa cells from spontaneously hypertensive rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:12

    Topics: 18-Hydroxycorticosterone; Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II;

1987
Systemic and renal hemodynamic changes after two-month treatment with enalapril in patients with essential hypertension.
    International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:12

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Electrolytes; Enalapril; Female; Hemodynamics; Human

1987
A ouabain-displacing factor in normal pregnancy, pregnancy-induced hypertension and pre-eclampsia.
    Clinical science (London, England : 1979), 1988, Volume: 74, Issue:3

    Topics: Adult; Aldosterone; Cardenolides; Catecholamines; Digoxin; Female; Humans; Hypertension; Natriuretic

1988
Inhibitory effect of enalapril on serum aldosterone in essential hypertension.
    Medicina, 1987, Volume: 47, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Enalapril; Female; Heart Rate; Humans; Hypertension;

1987
Enalapril and atenolol in essential hypertension: attenuation of hypotensive effects in combination.
    Clinical and experimental hypertension. Part A, Theory and practice, 1988, Volume: 10, Issue:1

    Topics: Aldosterone; Angiotensin II; Atenolol; Atrial Natriuretic Factor; Drug Interactions; Drug Therapy, C

1988
Effects of thiazide on erythrocyte sodium and potassium concentrations and Na+K+ATPase in hypertensive patients.
    Clinical and experimental hypertension. Part A, Theory and practice, 1988, Volume: 10, Issue:1

    Topics: Aldosterone; Benzothiadiazines; Diuretics; Erythrocytes; Humans; Hypertension; Male; Potassium; Reni

1988
Angiotensin-responsive aldosterone-producing adenoma masquerades as idiopathic hyperaldosteronism (IHA: adrenal hyperplasia) or low-renin essential hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1987, Volume: 5, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Dexamet

1987
Captopril versus enalapril: a comparison of 24 h humoral and hypotensive effects.
    Bollettino della Societa italiana di biologia sperimentale, 1987, Sep-30, Volume: 63, Issue:9

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Enalapril; Humans; Hypertension; Pept

1987
Effects of corticotropin-releasing factor (CRF) on aldosterone and 18-hydroxycorticosterone in essential hypertension and primary aldosteronism.
    Endocrinologia japonica, 1987, Volume: 34, Issue:6

    Topics: 18-Hydroxycorticosterone; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Corticosterone; Cor

1987
Effect of lisinopril monotherapy on renal hemodynamics.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1988, Volume: 11, Issue:6

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Creatinine; Electrolytes; Ena

1988
Antihypertensive activity of enalapril. Effect of ibuprofen and different salt intakes.
    Journal of clinical hypertension, 1987, Volume: 3, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pr

1987
[Plasma renin activity, levels of catecholamines and aldosterone in essential arterial hypertension treated with ACE inhibitors. Base values and values after stress].
    Bollettino della Societa italiana di biologia sperimentale, 1987, Nov-30, Volume: 63, Issue:11

    Topics: Adult; Aldosterone; Catecholamines; Dopamine; Enalapril; Epinephrine; Humans; Hypertension; Male; No

1987
Plasma cortisol and corticosteroid-binding globulin in essential hypertension.
    Clinical physiology and biochemistry, 1988, Volume: 6, Issue:2

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Child; Child, Preschool; Female;

1988
Mild hypertension in patients with suspected dilated cardiomyopathy: cause or consequence?
    African journal of medicine and medical sciences, 1988, Volume: 17, Issue:2

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Cardiomyopathy, Dilated; Electrolytes; Female; Heart Rate;

1988
Hypertension in pseudohypoparathyroidism type I.
    The American journal of medicine, 1988, Volume: 85, Issue:6

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Catecholamines; Child;

1988
[Acute hemodynamic and hormonal effects of enalapril in essential hypertension: relations between hormone levels and efficacy].
    Cardiologia (Rome, Italy), 1988, Volume: 33, Issue:7

    Topics: Aldosterone; Blood Pressure; Drug Evaluation; Enalapril; Heart Rate; Hemodynamics; Humans; Hypertens

1988
[High plasma renin activity in chronic obstructive pulmonary disease].
    Nihon Kyobu Shikkan Gakkai zasshi, 1988, Volume: 26, Issue:10

    Topics: Aged; Aldosterone; Female; Humans; Hypertension; Lung Diseases, Obstructive; Male; Middle Aged; Pept

1988
[Clinical use of magnetic resonance tomography for assessing adrenal function in patients with arterial hypertension].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1988, Volume: 11, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Diagnosis, Di

1988
Modulation of left ventricular hypertrophy by dietary salt and inhibition of angiotensin converting enzyme.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4

    Topics: Aldosterone; Animals; Body Weight; Cardiomegaly; Enalapril; Hypertension; Lisinopril; Peptidyl-Dipep

1988
Severe hypertension with absent secondary sex characteristics due to partial deficiency of steroid 17 alpha-hydroxylase activity.
    Journal of human hypertension, 1987, Volume: 1, Issue:1

    Topics: Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Aldost

1987
Effect of elevated blood pressure, renin and aldosterone on renal sodium handling in two-kidney Goldblatt hypertensive rats.
    Comparative biochemistry and physiology. A, Comparative physiology, 1986, Volume: 83, Issue:4

    Topics: Aldosterone; Animals; Blood Pressure; Female; Hypertension; Kidney; Rats; Rats, Inbred Strains; Rena

1986
Augmentation of renal blood flow and sodium excretion in hypertensive patients during blood pressure reduction by intravenous administration of the dopamine1 agonist fenoldopam.
    Circulation, 1987, Volume: 76, Issue:6

    Topics: Adult; Aldosterone; Benzazepines; Blood Pressure; Dose-Response Relationship, Drug; Female; Fenoldop

1987
The acute and chronic effects of betaxolol on blood pressure, renin-aldosterone, and renal function in essential hypertension.
    Journal of clinical pharmacology, 1987, Volume: 27, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Aldosterone; Betaxolol; Blood Pressure; Humans; Hypertension; Kid

1987
Effect of glucocorticoid deficiency on arterial pressure in conscious spontaneously hypertensive rats.
    American journal of hypertension, 1989, Volume: 2, Issue:2 Pt 1

    Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Dexamethasone; Glucocorticoids; Hypertension; M

1989
Chronic hypotensive effects of verapamil in angiotensin hypertension are steroid independent.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 13, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Chronic Disease; Dogs

1989
Nitrendipine, a calcium-entry blocker. Renal and humoral effects in human arterial hypertension.
    Archives of internal medicine, 1986, Volume: 146, Issue:1

    Topics: Adult; Aged; Aldosterone; Blood Volume; Body Fluids; Calcium Channel Blockers; Catecholamines; Elect

1986
[Effects of diltiazem on developing blood pressure and accompanying cardiac and vascular hypertrophy in SHR].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 86, Issue:3

    Topics: Aldosterone; Animals; Aorta; Aortic Diseases; Benzazepines; Cardiomegaly; Diltiazem; Hindlimb; Hyper

1985
Isomyosin transitions in ventricles of aldosterone-salt hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:2

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Cardiomegaly; Electrophoresis, Polyacrylamide Gel

1986
Endogenous opioid peptides: do they mediate the acute antihypertensive action of clonidine in humans?
    Hormone research, 1986, Volume: 23, Issue:4

    Topics: Adult; Aged; Aldosterone; beta-Endorphin; Blood Pressure; Clonidine; Endorphins; Humans; Hypertensio

1986
Effect of chronic infusion of atrial natriuretic factor on plasma and urinary aldosterone, plasma renin activity, blood pressure and sodium excretion in 2-K, 1-C hypertensive rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1986, Volume: 8, Issue:7

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Chronic Disease; Diuresis; Drug Eva

1986
[Effect of atriopeptin on the plasma renin-angiotensin system in rats].
    Zhonghua xin xue guan bing za zhi, 1986, Volume: 14, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Hypertension; Male; Rats; Rats, Inb

1986
Plasma levels of atrial natriuretic peptide are raised in essential hypertension during low and high sodium intake.
    Klinische Wochenschrift, 1987, Mar-02, Volume: 65, Issue:5

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Diet, Sodium-Restricted; Female; Humans; Hypert

1987
[Human atrial natriuretic peptide: a secretory product of the heart and its significance for physiology and clinical practice].
    Wiener klinische Wochenschrift, 1987, Mar-06, Volume: 99, Issue:5

    Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Diuresis; Heart Failure; Humans; Hypertensio

1987
[Possible correlations between the electrolyte picture and plasma levels of aldosterone in pregnancy complicated by hypertension].
    Recenti progressi in medicina, 1987, Volume: 78, Issue:4

    Topics: Adenosine Triphosphatases; Aldosterone; Erythrocytes; Female; Humans; Hypertension; Potassium; Pregn

1987
Hemodynamic and hormonal effects of atrial natriuretic factor in patients with essential hypertension.
    Journal of the American College of Cardiology, 1987, Volume: 10, Issue:4

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Epinephrine; Female; Hemodynamics; Humans; Hypertensi

1987
Aldosterone regulation during saline infusion: usefulness of aldosterone/cortisol ratio in the diagnosis of aldosterone-producing adenoma.
    Clinical and experimental pharmacology & physiology, 1987, Volume: 14, Issue:3

    Topics: Adenoma; Aldosterone; Atrial Natriuretic Factor; Chromatography, High Pressure Liquid; Humans; Hydro

1987
Plasma levels of human atrial natriuretic peptide in patients with hypertensive diseases.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:8

    Topics: Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Cross Reactions; Diet, Sodiu

1987
Alpha-h-ANP injection in normals, low renin hypertension and primary aldosteronism.
    Journal of steroid biochemistry, 1987, Volume: 27, Issue:4-6

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Diuresis; Heart Rate; Humans; Hydroco

1987
Changes in the plasma hANP level during long-term salt loading in patient with essential hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1988, Volume: 10, Issue:1

    Topics: Aged; Aldosterone; Atrial Natriuretic Factor; Female; Humans; Hypertension; Male; Middle Aged; Norep

1988
Renal, cardiovascular and hormonal effects of alpha-human atrial natriuretic peptide on essential hypertension.
    Chinese medical journal, 1987, Volume: 100, Issue:10

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Female; Heart; Humans; Hypertension; Kidney; Ma

1987
Plasma levels of atrial natriuretic peptide in patients with borderline and essential hypertension.
    The Tohoku journal of experimental medicine, 1988, Volume: 154, Issue:2

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Calcium; Female; Humans; Hypertension; Male; Renin

1988
[Physiologic importance of atrial natriuretic peptide in volume expansion and hypertension: experimental studies].
    Zeitschrift fur Kardiologie, 1988, Volume: 77 Suppl 2

    Topics: Aldosterone; Animals; Antibodies, Monoclonal; Atrial Natriuretic Factor; Blood Pressure; Blood Volum

1988
[Atrial natriuretic peptide (ANP) in essential hypertension: a humoral marker for salt sensitivity and hypertensive heart disease at a clinically asymptomatic stage?].
    Zeitschrift fur Kardiologie, 1988, Volume: 77 Suppl 2

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Catecholamines; Female; Heart Disease

1988
Efficacy and safety of cilazapril, a new angiotensin-converting enzyme inhibitor.
    American journal of hypertension, 1988, Volume: 1, Issue:3 Pt 3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Benzothiadiazines; Blood Pressure; Cilazapril

1988
[Role of atrial natriuretic peptide in the renal response to acute volume expansion in the normal and essential hypertensive patient].
    Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81 Spec No

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Volume; Female; Humans; Hypertension; Male; Mid

1988
[Arterial hypertension with hyperkalemia, tubular acidosis and normal renal function: Gordon syndrome and/or pseudohypoaldosteronism type II?].
    Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81 Spec No

    Topics: Acidosis, Renal Tubular; Aldosterone; Atrial Natriuretic Factor; Humans; Hyperkalemia; Hypertension;

1988
Salt sensitivity in blacks. Salt intake and natriuretic substances.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 12, Issue:5

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Black People; Blood Pressure; Dinoprostone; Dopamine;

1988
Radioimmunoassay of atrial natriuretic peptide in human plasma: application to studies of volume and blood pressure homeostasis.
    Physiologia Bohemoslovaca, 1988, Volume: 37, Issue:4

    Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Electrolytes; Extracellular Space; Heart Fai

1988
Response of atrial natriuretic peptide to acute saline loading in essential hypertension.
    The American journal of physiology, 1988, Volume: 255, Issue:6 Pt 2

    Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Female; Glomerular Filtra

1988
Does the renin-angiotensin-aldosterone system modify cardiac structure and function in essential hypertension?
    The American journal of medicine, 1988, Mar-11, Volume: 84, Issue:3A

    Topics: Aldosterone; Cardiomegaly; Female; Humans; Hypertension; Male; Myocardium; Renin-Angiotensin System;

1988
A new Australian kindred with the syndrome of hypertension and hyperkalaemia has dysregulation of atrial natriuretic factor.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4

    Topics: Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Australia; Fludrocortisone; Humans; Hyperkal

1988
Dopaminergic control of aldosterone secretion is not mediated by atrial natriuretic factor in patients with essential hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4

    Topics: Aldosterone; Atrial Natriuretic Factor; Deoxyepinephrine; Dopamine; Humans; Hypertension; Metoclopra

1988
Long-term antihypertensive treatment may induce normalization of left ventricular mass before complete regression of vascular structural changes: consequences for cardiac function at rest and during stress.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Drug Admi

1988
Effects of chronically administered atrial natriuretic factor in aldosterone-infused hypertensive rats.
    Japanese circulation journal, 1988, Volume: 52, Issue:12

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Hypertension; Infusions, Intravenou

1988
[Role of ANP in the regulation of blood pressure].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1988, Volume: 33, Issue:14

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Humans; Hypertension; Sodium; Vasod

1988
Plasma beta-endorphin levels in primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 60, Issue:2

    Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Age

1985
[Concentration of adrenocorticotrophic hormone and aldosterone secretion in essential hypertension and hyperaldosteronism].
    Kardiologiia, 1985, Volume: 25, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Humans; Hydrocortisone; Hyperaldosteronism; Hyperte

1985
Adrenocortical function in deoxycorticosterone acetate (DOCA)-hypertensive Yucatan miniature swine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 178, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; An

1985
Cigarette smoking in hypertensive patients. Blood pressure and endocrine responses.
    The American journal of medicine, 1985, Volume: 78, Issue:4

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Endocrine Gla

1985
Urinary 6-keto-PGF1 alpha after captopril and indomethacin: possible contribution of PGI2 to the antihypertensive mechanism of ACE inhibitors.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1985, Volume: 13

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopri

1985
Plasma Na+-K+ ATPase inhibitory activity in normal and hypertensive subjects: relationship to intracellular electrolytes and blood pressure.
    Clinical and experimental hypertension. Part A, Theory and practice, 1985, Volume: 7, Issue:5-6

    Topics: Adult; Aldosterone; Animals; ATPase Inhibitory Protein; Blood Pressure; Blood Proteins; Electrolytes

1985
The effect of long-term verapamil treatment on the secretion of cortisol and aldosterone in subjects with normal and high blood pressure.
    Experimental and clinical endocrinology, 1985, Volume: 85, Issue:2

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hyp

1985
[The acute effects of the new angiotensin I-converting enzyme inhibitor, enalapril maleate, on blood pressure, plasma renin, aldosterone and kinins in hypertensive patients].
    Nihon Naibunpi Gakkai zasshi, 1985, May-20, Volume: 61, Issue:5

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Brad

1985
Relationships among endogenous digitalis-like factors in essential hypertension.
    Federation proceedings, 1985, Volume: 44, Issue:12

    Topics: Aldosterone; Animals; Blood Proteins; Calcium; Cardenolides; Digoxin; Epinephrine; Humans; Hypertens

1985
Effect of enalapril on renin, angiotensin converting enzyme activity, aldosterone and prostaglandins in patients with hypertension.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1985, Volume: 8, Issue:3

    Topics: Adult; Aldosterone; Alprostadil; Creatinine; Dinoprostone; Enalapril; Female; Humans; Hypertension;

1985
Enalapril in essential hypertension.
    Drugs, 1985, Volume: 30 Suppl 1

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Catecholamines; Enalapril; Female

1985
Natriuretic effect and changes in renal haemodynamics induced by enalapril in essential hypertension.
    Drugs, 1985, Volume: 30 Suppl 1

    Topics: Adolescent; Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Enalapril; Female; Glomerul

1985
Effect of sodium intake on the excretion of urinary natriuretic factor in essential hypertensives.
    Endocrinologia japonica, 1985, Volume: 32, Issue:3

    Topics: Aldosterone; Digoxin; Humans; Hypertension; Natriuretic Agents; Radioimmunoassay; Sodium; Sodium Chl

1985
Effects of converting enzyme inhibition on blood pressure, plasma renin activity (PRA) and plasma aldosterone in hypertensive diabetics compared to patients with essential hypertension.
    Journal of hypertension, 1985, Volume: 3, Issue:4

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Diabetic Angiopath

1985
Are non-modulating patients with essential hypertension a distinct subgroup? Implications for therapy.
    The American journal of medicine, 1985, Sep-27, Volume: 79, Issue:3C

    Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Female; Furosemide; Humans; Hypertension; Kidney

1985
Blood pressure response to enalaprilic acid in essential hypertension: dose-response and effect of pre-treatment with furosemide.
    European journal of clinical pharmacology, 1985, Volume: 29, Issue:1

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Dose-Response Re

1985
24-H patterns of erythrocyte membrane-bound Na/K ATPase, plasma renin and aldosterone in normotensives and essential hypertensives.
    Regulatory peptides. Supplement, 1985, Volume: 4

    Topics: Adolescent; Adult; Aldosterone; Erythrocyte Membrane; Female; Humans; Hypertension; Male; Renin; Sod

1985
Acute effects of the new oral angiotensin converting enzyme inhibitor 1-(D-3-acetylthio-2-methylpropanoyl)-L-prolyl-L-phenylalanine (Alacepril) in essential hypertension.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 49, Issue:2

    Topics: Administration, Oral; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure;

1985
Changes in blood pressure and body fluid volumes during diuretic therapy in patients with essential hypertension who receive enalapril.
    Clinical pharmacology and therapeutics, 1986, Volume: 39, Issue:1

    Topics: Aged; Aldosterone; Blood Pressure; Body Fluids; Body Weight; Chlorthalidone; Creatinine; Drug Evalua

1986
Non-modulating essential hypertension: a subset particularly responsive to converting enzyme inhibitors.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1985, Volume: 3, Issue:2

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertens

1985
[Round-table conference "Biochemical diagnosis of arterial hypertension"].
    Przeglad lekarski, 1985, Volume: 42, Issue:9

    Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Catechol

1985
Diagnosis and pathophysiology of Cushing's syndrome.
    Comprehensive therapy, 1986, Volume: 12, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Cushing Syndrome; Femal

1986
[Clinical significance of serum angiotensin I-converting enzyme in essential hypertension].
    Nihon Naibunpi Gakkai zasshi, 1985, Dec-20, Volume: 61, Issue:12

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Bradykinin; Circadian Rhythm; Creatinine;

1985
Dopaminergic control of aldosterone secretion in hypertensive patients chronically treated with an angiotensin converting enzyme inhibitor.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1986, Volume: 18, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme

1986
Renal sodium excretion and atrial natriuretic factor.
    The American journal of the medical sciences, 1986, Volume: 291, Issue:3

    Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Extracellular Space; Glomerular Filtration Rate; Hu

1986
Effect of alacepril on renin-angiotensin-aldosterone system and kallikrein-kinin-prostaglandin system in experimental animals.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Angiotensin I; Animals; Antihypertensive Agents; Blood Pr

1986
[Various humoral factors regulating blood pressure in patients with hypertension during treatment by an impulse magnetic field].
    Kardiologiia, 1986, Volume: 26, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Cyclic AMP; Cyclic GMP; Dinoprost; Female; Homeostasis; Humans;

1986
Cortisol resistance in man.
    Advances in experimental medicine and biology, 1986, Volume: 196

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Alkalosis; Cell Transformation, Viral; Child; Circa

1986
[Arterial hypertension in alcohol withdrawal syndrome].
    Minerva cardioangiologica, 1986, Volume: 34, Issue:4

    Topics: Adult; Aged; Aldosterone; Cyclic AMP; Ethanol; Female; Humans; Hypertension; Male; Middle Aged; Reni

1986
Studies on the antihypertensive effect of single doses of the angiotensin converting enzyme inhibitor ramipril (HOE 498) in man.
    European journal of clinical pharmacology, 1986, Volume: 30, Issue:5

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood P

1986
[Results of a 5-year study with captopril in patients with severe therapy-resistant hypertension].
    Klinische Wochenschrift, 1986, Aug-01, Volume: 64, Issue:15

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Drug

1986
[Mechanisms of hypertension in patients with terminal kidney failure on programmed hemodialysis].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:8

    Topics: Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Kidney Failure, Chronic; Peptidyl-Dipeptid

1986
Zona glomerulosa cell responses to atrial natriuretic factor in genetically hypertensive rats.
    The American journal of physiology, 1986, Volume: 251, Issue:4 Pt 2

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood

1986
Effect of nifedipine in hypertension not controlled by converting enzyme inhibitor and diuretic.
    Postgraduate medical journal, 1986, Volume: 62 Suppl 1

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Drug Therapy, Combination; Enalapril; Female; Furosem

1986
Enalaprilat: an intravenous substitute for oral enalapril therapy. Humoral and pharmacokinetic effects.
    Journal of clinical hypertension, 1986, Volume: 2, Issue:3

    Topics: Administration, Oral; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihyp

1986
Spironolactone-reversible rickets associated with 11 beta-hydroxysteroid dehydrogenase deficiency syndrome.
    The Journal of pediatrics, 1986, Volume: 109, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenocorticotropic Hormone; Aldosterone; Alkalosis; Bone and

1986
[Clinical pharmacology of enalapril in hypertension with chronic renal failure].
    Archives des maladies du coeur et des vaisseaux, 1986, Volume: 79, Issue:6

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Enalapril; Heart Rate; Humans

1986
Humoral and blood pressure effects of the angiotensin converting enzyme inhibitor ramipril in essential hypertension.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:11

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressur

1986
Effects of aldosterone and adrenocorticotropic hormone on urinary kallikrein excretion.
    Nihon Jinzo Gakkai shi, 1986, Volume: 28, Issue:9

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Humans; Hypertension; Infusions, Intravenou

1986
[Mechanisms of the hypotensive action of captopril in essential hypertension].
    Kardiologiia, 1986, Volume: 26, Issue:12

    Topics: Adult; Aldosterone; Captopril; Epinephrine; Hemodynamics; Humans; Hypertension; Kallikreins; Middle

1986
[Influence of endogenous renin-angiotensin system on plasma aldosterone responsiveness to metoclopramide].
    Nihon Naibunpi Gakkai zasshi, 1987, Feb-20, Volume: 63, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Diuretics; Dopamine; Female; Humans; Hyperaldostero

1987
Lisinopril in hypertensive patients with and without renal failure.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:1

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Creatinine; Enal

1987
Characterization of the alpha-1 adrenergic receptors in the thoracic aorta of control and aldosterone hypertensive rats: correlation of radioligand binding with potassium efflux and contraction.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Aorta, Thoracic; Dibenzylchlorethamine; Hypertension; Muscle C

1987
[Effects of alpha-human atrial natriuretic peptide on plasma steroids and renal function in the human].
    Nihon Jinzo Gakkai shi, 1987, Volume: 29, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Catechol

1987
Effects of enalapril maleate on blood pressure, renin-angiotensin-aldosterone system, and peripheral sympathetic activity in essential hypertension.
    Clinical therapeutics, 1987, Volume: 9, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Enalapril; Exercise Test; Female; Humans; Hypert

1987
Single oral administration of captopril may not bring an improvement in screening of primary aldosteronism.
    Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:2-3

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diet; Humans; Hyperaldosteronism;

1987
Effect of beta-adrenergic receptor blockade on atrial natriuretic peptide in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1987, Volume: 10, Issue:2

    Topics: Acebutolol; Adult; Aged; Aldosterone; Atenolol; Atrial Natriuretic Factor; Cyclic GMP; Female; Human

1987
Sodium excretion in normal and hypertensive pregnancy: a prospective study.
    American journal of obstetrics and gynecology, 1988, Volume: 159, Issue:2

    Topics: Aldosterone; Cross-Sectional Studies; Diet; Diet, Sodium-Restricted; Female; Humans; Hypertension; I

1988
[Influence of sodium intake on antihypertensive effect of calcium antagonist].
    Nihon Jinzo Gakkai shi, 1988, Volume: 30, Issue:6

    Topics: Administration, Oral; Aldosterone; Blood Pressure; Catecholamines; Female; Heart Rate; Humans; Hyper

1988
Natriuretic and renal hemodynamic effects of nicardipine in essential hypertension.
    Kidney international. Supplement, 1988, Volume: 25

    Topics: Administration, Oral; Aldosterone; Blood Pressure; Heart Rate; Hemodynamics; Humans; Hypertension; I

1988
Normal vitamin D and mineral metabolism in essential hypertension.
    The American journal of the medical sciences, 1988, Volume: 296, Issue:4

    Topics: Adult; Aldosterone; Calcifediol; Calcitriol; Calcium; Creatinine; Electrolytes; Female; Humans; Hype

1988
[Effect of captopril on renin-aldosterone system in essential hypertension].
    Zhonghua xin xue guan bing za zhi, 1988, Volume: 16, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Captopril; Chromatography, High Pressure Liquid; Female; Humans;

1988
[The role of hormonal factors in the pathogenesis of juvenile arterial hypertension].
    Vrachebnoe delo, 1988, Issue:8

    Topics: Adolescent; Adult; Aldosterone; Estradiol; Exercise Test; Humans; Hypertension; Renin; Testosterone

1988
Biochemical changes associated with thermal biofeedback treatment of hypertension.
    Biofeedback and self-regulation, 1988, Volume: 13, Issue:2

    Topics: Adult; Aged; Aldosterone; Biofeedback, Psychology; Blood Pressure; Female; Humans; Hypertension; Mal

1988
Influence of sublingual captopril on plasma catecholamine levels during hypertensive emergencies and cold immersion.
    The American journal of medicine, 1988, Mar-11, Volume: 84, Issue:3A

    Topics: Administration, Sublingual; Adult; Aged; Aldosterone; Blood Pressure; Captopril; Catecholamines; Col

1988
[Effects of high sodium diet on dopaminergic mechanism in normal and hypertensive subjects].
    Nihon Naibunpi Gakkai zasshi, 1988, Nov-20, Volume: 64, Issue:11

    Topics: Adult; Aldosterone; Blood Pressure; Dopamine; Epinephrine; Heart Rate; Humans; Hypertension; Metoclo

1988
[Effect of immersion (WI) in mineral water on plasma renin activity (PRA) and aldosterone (ALD) and vasopressin (VP) levels in the blood of patients with arterial hypertension].
    Kardiologia polska, 1988, Volume: 31 Suppl 1

    Topics: Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Immersion; Mineral Waters; Renin; Vasopres

1988
Sodium-renin-aldosterone relations in normal and hypertensive pregnancy.
    British journal of obstetrics and gynaecology, 1988, Volume: 95, Issue:12

    Topics: Adult; Aldosterone; Blood Volume; Diet, Sodium-Restricted; Female; Humans; Hypertension; Pregnancy;

1988
[A 54-year-old patient with muscle weakness, hypokalemia and arterial hypertension].
    Der Internist, 1988, Volume: 29, Issue:10

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Female; Humans; Hypertension; Hypokalemia; Middle Ag

1988
Intracellular free Ca2+ in platelets of essential hypertensive patients. Lack of correlation with clinical and laboratory data.
    Journal of human hypertension, 1988, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Blood Platelets; Blood Pressure; Calcium; Cholesterol; Female; Human

1988
The effect of ageing on the plasma renin-angiotensin-aldosterone system in elderly hypertensive patients.
    Journal of human hypertension, 1988, Volume: 2, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin;

1988
Cardiovascular and neurohormonal changes following central sympathetic blockade with clonidine in human unilateral renal artery stenosis.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4

    Topics: Adult; Aged; Aldosterone; Captopril; Clonidine; Hemodynamics; Humans; Hypertension; Middle Aged; Nor

1988
Norepinephrine and calcium responses to altered sodium intake in modulating and non-modulating high-renin hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4

    Topics: Aldosterone; Blood Pressure; Calcium; Humans; Hypertension; Norepinephrine; Renin; Sodium

1988
[Changes in the indicators of the renin-angiotensin-aldosterone system, kallikrein-kinin system and arterial blood pressure in elderly patients with essential hypertension treated with captopril].
    Kardiologiia, 1988, Volume: 28, Issue:12

    Topics: Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Captopril; Female; Humans; Hypertension; Kall

1988
[Studies of the effect of bromocriptine on the serum prolactin, aldosterone and cortisol levels and plasma renin activity in patients with essential hypertension].
    Polskie Archiwum Medycyny Wewnetrznej, 1988, Volume: 80, Issue:1

    Topics: Adult; Aldosterone; Bromocriptine; Enzyme Inhibitors; Humans; Hydrocortisone; Hypertension; Middle A

1988
Mechanisms of cyclosporine A hypertension.
    Transplantation proceedings, 1987, Volume: 19, Issue:1 Pt 2

    Topics: Aldosterone; Animals; Arteries; Blood Pressure; Captopril; Cyclosporins; Electric Stimulation; Hyper

1987
Infected hand injury in a hypertensive patient.
    Hospital practice (Office ed.), 1987, Oct-30, Volume: 22, Issue:10A

    Topics: Adrenal Glands; Adult; Aldosterone; Antihypertensive Agents; Hand Injuries; Humans; Hyperplasia; Hyp

1987
[Hemodynamic indices and the renin and aldosterone levels of the blood plasma in patients with different forms of arterial hypertension undergoing combined kristepin and propranolol treatment].
    Kardiologiia, 1988, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Clopamide; Dihydroergotoxine; Drug Combinations; Drug Therapy, Combi

1988
Short- and long-term efficacy of nifedipine in hypertensive patients with impaired renal function, with special reference to influencing factors.
    Journal of clinical hypertension, 1987, Volume: 3, Issue:4

    Topics: Adult; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Creatinine; Female; Humans; Hypertension; K

1987
[Acute response to calcium inhibitors in secondary arterial hypertension: does renin play a role?].
    Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81 Spec No

    Topics: Adult; Aldosterone; Blood Pressure; Heart Rate; Humans; Hyperaldosteronism; Hypertension; Hypertensi

1988
[Segmental renal hypoplasia of an adult originating from pseudo-tumor hyperreninism].
    Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81 Spec No

    Topics: Adult; Aldosterone; Captopril; Humans; Hypertension; Kidney; Male; Microscopy, Electron; Nephrectomy

1988
Prevalence and clinical peculiarities of essential hypertension in a population living at high altitude.
    Cor et vasa, 1985, Volume: 27, Issue:1

    Topics: Adult; Age Factors; Aldosterone; Alkalosis, Respiratory; Altitude; Altitude Sickness; Cardiomegaly;

1985
Urinary kallikrein in mild to moderate essential hypertension.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1985, Volume: 13

    Topics: Aldosterone; Female; Furosemide; Humans; Hypertension; Kallikreins; Male; Middle Aged; Natriuresis;

1985
Participation of endogenous catecholamines in the regulation of left ventricular mass in progeny of hypertensive parents.
    Circulation, 1985, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Atenolol; Blood Pressure; Blood Volume; Body Weight; Cardiomegaly; C

1985
Influence of an enriched dietary sodium chloride regime during gestation and suckling and post-natally on the ontogeny of hypertension in the rat.
    Journal of hypertension, 1988, Volume: 6, Issue:7

    Topics: 18-Hydroxydesoxycorticosterone; Aldosterone; Angiotensin I; Animals; Animals, Suckling; Blood Pressu

1988
[Is the renin-angiotensin system implicated in the hypertensive effect of a water-soluble tissue extract?].
    Revista espanola de fisiologia, 1988, Volume: 44, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cattle; Female; Hypertension; Male; Rats; Rats

1988
Aldosterone and magnesium in essential arterial hypertension.
    Clinical physiology and biochemistry, 1988, Volume: 6, Issue:6

    Topics: Adult; Aldosterone; Calcium; Female; Humans; Hypertension; Magnesium; Male; Middle Aged; Potassium

1988
A case of glucocorticoid-suppressible hyperaldosteronism with aldosterone producing adenoma.
    Endocrinologia japonica, 1988, Volume: 35, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Dexamethasone; Female; Glucoco

1988
[Aldosterone metabolites in spontaneously hypertensive rats].
    Nihon Naibunpi Gakkai zasshi, 1988, Nov-20, Volume: 64, Issue:11

    Topics: Aldosterone; Animals; Chromatography, High Pressure Liquid; Cytoplasm; Hypertension; Injections, Int

1988
Mineralocorticoids are not involved in the antihypertensive effect of neonatal thymectomy in the genetically hypertensive LH rat.
    Clinical and experimental pharmacology & physiology, 1988, Volume: 15, Issue:11

    Topics: Aldosterone; Animals; Animals, Newborn; Blood Pressure; Desoxycorticosterone; Disease Models, Animal

1988
[A syndrome of arterial hypertension caused by a combination of 2 adrenal gland tumors].
    Klinicheskaia khirurgiia, 1988, Issue:12

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hypertension; Neoplasms, Multi

1988
Dopamine and aldosterone in adrenal glomerulosa cells in spontaneously hypertensive rats.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4

    Topics: Adrenal Glands; Adrenal Medulla; Aldosterone; Animals; Catecholamines; Dopamine; Hypertension; Rats;

1988
Effects of intracerebroventricular infusion of aldosterone on blood pressure and sodium and potassium concentrations in cerebral spinal fluid in rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1988, Volume: 10 Suppl 1

    Topics: Aldosterone; Animals; Blood Pressure; Brain; Hypertension; Infusion Pumps; Male; Potassium; Rats; Ra

1988
Urinary excretion of aldosterone metabolite Kelly-M1 in patients with adrenal dysfunction.
    Journal of steroid biochemistry, 1988, Volume: 29, Issue:3

    Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Aldosterone; Cysti

1988
Zona glomerulosa function after life-long suppression in two siblings with the hypertensive virilizing form of congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1988, Volume: 66, Issue:2

    Topics: 18-Hydroxycorticosterone; Adolescent; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Aldosterone;

1988
Therapeutic results of primary aldosteronism with special reference to renal or renovascular lesions.
    International urology and nephrology, 1988, Volume: 20, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Diet, Sodium-Restricted; Female; Furosemide; H

1988
Steroid-induced hypertension in patients with nephrotic syndrome.
    Nephron, 1988, Volume: 48, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Blood Volume; Female; Glomerulonephritis; Humans; Hypertension; Male

1988
Acute hypertensive and natriuretic responses following preoptic hypothalamic lesions.
    The American journal of the medical sciences, 1988, Volume: 295, Issue:4

    Topics: Aldosterone; Animals; Blood Pressure; Blood Volume; Corticosterone; Heart Rate; Hypertension; Male;

1988
Sodium sensitivity in normotensive and borderline hypertensive humans.
    The American journal of the medical sciences, 1988, Volume: 295, Issue:4

    Topics: Aldosterone; Black People; Blood Pressure; Body Weight; Cardiac Output; Conjunctiva; Echocardiograph

1988
[Plasma levels of catecholamine, renin activity and aldosterone during operations in patients with hypertension].
    Masui. The Japanese journal of anesthesiology, 1988, Volume: 37, Issue:2

    Topics: Adult; Aged; Aldosterone; Catecholamines; Female; Humans; Hypertension; Male; Middle Aged; Renin; Su

1988
Effect of penbutolol on circadian blood pressure, and renin, aldosterone and cortisol levels in patients with essential hypertension.
    Acta cardiologica, 1988, Volume: 43, Issue:1

    Topics: Administration, Oral; Adult; Aldosterone; Blood Pressure; Circadian Rhythm; Female; Humans; Hydrocor

1988
Long-term systemic hypertension in children after successful repair of coarctation of the aorta.
    American heart journal, 1988, Volume: 115, Issue:6

    Topics: Aldosterone; Aortic Coarctation; Blood Pressure; Child; Female; Heart Rate; Humans; Hypertension; Ma

1988
Sodium sensitivity in human subjects. Hemodynamic and hormonal correlates.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:6 Pt 2

    Topics: Adult; Aldosterone; Female; Hemodynamics; Humans; Hypertension; Male; Renin; Sodium, Dietary

1988
The pattern of plasma renin activity and aldosterone system in patients with sustained hydronephrosis.
    International urology and nephrology, 1987, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Child; Female; Humans; Hydronephrosis; Hypertension; Kidney; Male; M

1987
Effect of high calcium intake on pressor responsivity in hypertensive rats.
    The American journal of physiology, 1987, Volume: 252, Issue:6 Pt 2

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Calcium, Dietary; Dose-Response Relationship,

1987
[Radioimmunologic determination of aldosterone and renin in the blood in the diagnosis of different forms of arterial hypertension].
    Meditsinskaia radiologiia, 1987, Volume: 32, Issue:7

    Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Rena

1987
Effect of one year of thiazide therapy on plasma volume, renin, aldosterone, lipids and urinary metanephrines in systolic hypertension of elderly patients.
    The American journal of cardiology, 1987, Aug-01, Volume: 60, Issue:4

    Topics: Aged; Aldosterone; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Lipids; Metanephrin

1987
The gerontological decline of the renin-aldosterone system: a chronobiological approach extended to essential hypertension.
    Journal of gerontology, 1987, Volume: 42, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Circadian Rhythm; Female; Humans; Hypertension; Male; M

1987
Effects of sodium intake on the captopril test for primary aldosteronism.
    Japanese heart journal, 1987, Volume: 28, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Diet; Female; Humans; Hyperaldosteronism; Hypertensio

1987
[The renin-angiotensin-aldosterone system in obesity associated with essential arterial hypertension].
    Recenti progressi in medicina, 1987, Volume: 78, Issue:4

    Topics: Aldosterone; Circadian Rhythm; Humans; Hypertension; Obesity; Renin; Renin-Angiotensin System

1987
Renin suppression by saline is blunted in nonmodulating essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1987, Volume: 10, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged;

1987
"Salt-sensitive" essential hypertension in men. Is the sodium ion alone important?
    The New England journal of medicine, 1987, Oct-22, Volume: 317, Issue:17

    Topics: Aged; Aldosterone; Blood Pressure; Body Weight; Citrates; Citric Acid; Humans; Hypertension; Male; M

1987
Essential arterial hypertension: plasma and urinary aldosterone alterations.
    Southern medical journal, 1987, Volume: 80, Issue:10

    Topics: Adult; Age Factors; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin; Sodium

1987
Efficacy and safety of lasilactone, a new combination diuretic, in essential hypertension.
    General pharmacology, 1987, Volume: 18, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Drug Combinations; Female; Furosemide; Humans; Hypertension; Mal

1987
Renin and aldosterone in hypertensive blacks.
    Journal of clinical hypertension, 1987, Volume: 3, Issue:3 Suppl

    Topics: Adult; Aged; Aldosterone; Black People; Female; Humans; Hypertension; Male; Middle Aged; Renin

1987
[Detection of primary aldosteronism using the captopril test].
    Wiener klinische Wochenschrift, 1987, Sep-11, Volume: 99, Issue:17

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Captopril; Female; Humans; Hyp

1987
[Renin-angiotensin-aldosterone system in hypertension patients who have had a cerebral stroke].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1987, Volume: 87, Issue:9

    Topics: Aged; Aldosterone; Cerebrovascular Disorders; Chronic Disease; Humans; Hypertension; Middle Aged; Re

1987
[Structural and functional status of the adrenal cortex in patients with arterial hypertension (comparison of computerized-tomographic and clinico-biochemical data)].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1987, Volume: 10, Issue:2

    Topics: 17-Ketosteroids; Adrenal Cortex; Aldosterone; Humans; Hydrocortisone; Hypertension; Renin; Tomograph

1987
Dopamine blockade abolishes the exaggerated natriuresis of essential hypertension.
    Journal of hypertension, 1987, Volume: 5, Issue:5

    Topics: Adult; Aldosterone; Blood Pressure; Creatinine; Humans; Hypertension; Immersion; Male; Metoclopramid

1987
Role of renal kallikrein in modulating the antihypertensive effect of a single oral dose of captopril in normal- and low-renin essential hypertensives.
    Journal of hypertension, 1987, Volume: 5, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Captopril; Diuresis; Female; Humans; Hypertension; Kallikreins;

1987
Effects of calcium loading in DOCA-salt hypertensive rats.
    Japanese circulation journal, 1987, Volume: 51, Issue:11

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Calcium; Desoxycorticosterone; Drinking; Epinephr

1987
Hemodynamic and neurohumoral factors in the response of hypertensives to hydrochlorothiazide therapy.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1987, Volume: 10, Issue:6

    Topics: Aldosterone; Benzothiadiazines; Blood Pressure; Diuretics; Epinephrine; Female; Hemodynamics; Humans

1987
Calcium antagonists and responsiveness of the adrenal glands to aldosterone-releasing stimuli in hypertensive patients.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1987, Volume: 5, Issue:4

    Topics: Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Calcium Channel Blockers; Drug Evaluation;

1987
Effects of felodipine and metoprolol on blood pressure, plasma renin, angiotensin II, aldosterone and catecholamines in hypertensive patients.
    Drugs, 1987, Volume: 34 Suppl 3

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Electro

1987
Blunted aldosterone responsiveness to angiotensin II in normotensive subjects with familial predisposition to essential hypertension.
    Journal of hypertension, 1988, Volume: 6, Issue:1

    Topics: Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Humans; Hypertension; Male; Sodium, Dietary

1988
Hypertensive mechanisms associated with centrally administered aldosterone in dogs.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:6 Pt 2

    Topics: Aldosterone; Hemodynamics; Hypertension; Injections, Intraventricular; Injections, Subcutaneous; Mal

1988
[Studies on abnormalities of adrenal steroidogenesis in essential hypertension, primary aldosteronism and renovascular hypertension: responses of plasma steroids to angiotensin III].
    Nihon Naibunpi Gakkai zasshi, 1988, May-20, Volume: 64, Issue:5

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adult; Aldosterone; Angiotensin II; Angiotensin III; Circad

1988
Dose-response studies of intracerebroventricular infusion of aldosterone in sensitized and non-sensitized rats.
    Journal of hypertension, 1988, Volume: 6, Issue:6

    Topics: Aldosterone; Animals; Cerebral Ventricles; Dose-Response Relationship, Drug; Hypertension; Infusions

1988
Lack of increase in sodium concentration of cerebrospinal fluid in DOCA-salt hypertensive rats.
    American journal of hypertension, 1988, Volume: 1, Issue:3 Pt 3

    Topics: 18-Hydroxycorticosterone; Adrenalectomy; Aldosterone; Animals; Arginine Vasopressin; Blood Pressure;

1988
Primary aldosteronism at Henry Ford Hospital in the 1980s.
    Henry Ford Hospital medical journal, 1987, Volume: 35, Issue:4

    Topics: Adrenalectomy; Adult; Aldosterone; Combined Modality Therapy; Female; Humans; Hyperaldosteronism; Hy

1987
[Primary hyperaldosteronism: diagnosis, treatment and histopathological findings in 15 cases].
    Revista medica de Chile, 1987, Volume: 115, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Female; Humans; Hyperaldostero

1987
Apparent mineralocorticoid excess causing hypertension and hypokalemia in children.
    Clinical and experimental hypertension. Part A, Theory and practice, 1986, Volume: 8, Issue:4-5

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Child; Child, Preschool; Female; Humans; Hydroco

1986
Humoral factors involved in the regulation of sodium-fluid balance in man. III. Renal prostaglandins and renin-angiotensin-aldosterone system in hypertensive disorders.
    Acta physiologica et pharmacologica Bulgarica, 1986, Volume: 12, Issue:4

    Topics: Aldosterone; Dinoprost; Dinoprostone; Epinephrine; Humans; Hypertension; Hypertension, Renal; Kidney

1986
Cellular sodium turnover in obese hypertensive men.
    Acta medica Scandinavica. Supplementum, 1986, Volume: 714

    Topics: Adult; Aldosterone; Erythrocytes; Humans; Hypertension; Male; Middle Aged; Obesity; Potassium; Sodiu

1986
Circadian rhythms of urinary sodium, potassium and some agents influencing their excretion in young borderline hypertensives.
    Endocrinologia experimentalis, 1986, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Circadian Rhythm; Corticosterone; Desoxycorticosterone; Dinoprost; D

1986
Immediate and short-term hemodynamic effects of diltiazem in patients with hypertension.
    Circulation, 1986, Volume: 73, Issue:1

    Topics: Adult; Aged; Aldosterone; Benzazepines; Blood Pressure; Diltiazem; Dopamine; Epinephrine; Female; He

1986
Multiple factors contribute to the pathogenesis of hypertension in Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 62, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Captopr

1986
New insights into the medical management of primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:1

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Angiotensin II; Calcium Channel Blockers; Fem

1986
Hypertension and kidney transplantation.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1986, Volume: 7, Issue:3

    Topics: Aldosterone; Animals; Cyclosporins; Electrolytes; Glucocorticoids; Graft Survival; Hormones; Humans;

1986
Short-term augmented calcium intake has no effect on sodium homeostasis.
    Clinical pharmacology and therapeutics, 1986, Volume: 39, Issue:4

    Topics: Administration, Oral; Adult; Aldosterone; Analysis of Variance; Blood Pressure; Calcium; Creatinine;

1986
Detection of primary aldosteronism by the 6-hour integrated aldosterone/renin ratio.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Blood Pressure; Female; Humans; Hyperald

1986
Interplay of various factors in glucose-induced hyperkalemia during captopril treatment.
    International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:2

    Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Captopril; Glomerular Filtration Rate; Glucose; G

1986
Hypertension and hypokalaemia due to a renin-secreting kidney tumour. Primary reninism.
    The Netherlands journal of medicine, 1986, Volume: 29, Issue:3

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Hypokalemia; Kidney Neoplasms; Renin

1986
[Radioimmunologic analysis of the status of the renin-angiotensin-aldosterone system in arterial hypertension].
    Radiologia diagnostica, 1986, Volume: 27, Issue:1

    Topics: Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension; Radioimmunoassay; Renin

1986
Renal kallikrein in diabetic patients with hypertension accompanied by nephropathy.
    Diabetologia, 1986, Volume: 29, Issue:3

    Topics: Adult; Aged; Aldosterone; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies;

1986
Spectrum of deranged sodium homeostasis in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:5

    Topics: Adult; Aldosterone; Blood Pressure; Creatinine; Homeostasis; Humans; Hypertension; Immersion; Male;

1986
[Progressive hyperkalemia during chronic captopril therapy (pharmacological hypoaldosteronism)].
    Orvosi hetilap, 1986, Apr-13, Volume: 127, Issue:15

    Topics: Aged; Aldosterone; Captopril; Dose-Response Relationship, Drug; Humans; Hyperkalemia; Hypertension;

1986
Body sodium/blood volume state in normotensive members of normotensive and hypertensive families.
    Journal of hypertension, 1986, Volume: 4, Issue:2

    Topics: Aldosterone; Blood Pressure; Blood Volume; Humans; Hypertension; Male; Renin; Sodium; Water-Electrol

1986
Blood pressure control in normotensive members of hypertensive families.
    Kidney international, 1986, Volume: 29, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Creatinine; Dose-Response Relationship, Drug; Ep

1986
Antihypertensive effect of a new calcium channel blocker, FK 235, in essential hypertension.
    Research communications in chemical pathology and pharmacology, 1986, Volume: 52, Issue:1

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hyperte

1986
Effect of exercise on plasma concentrations of arginine vasopressin, angiotensin II and aldosterone in hypertensive and normotensive renal transplant recipients.
    Scandinavian journal of clinical and laboratory investigation, 1986, Volume: 46, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Blood Pressure; Exercise Test; Female; Hea

1986
Diurnal patterns of blood pressure, heart rate and vasoactive hormones in normal man.
    Clinical and experimental hypertension. Part A, Theory and practice, 1986, Volume: 8, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Catecholamines; Circadian Rhythm; Female; Heart

1986
The renin-angiotensin system in hypothyroidism of short duration.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1986, Volume: 18, Issue:5

    Topics: Adult; Aldosterone; Electrophysiology; Female; Humans; Hypertension; Hypothyroidism; Intestinal Muco

1986
[Dynamic model of the circadian rhythm of renin activity and aldosterone concentration in the blood plasma of hypertension patients].
    Vrachebnoe delo, 1986, Issue:5

    Topics: Adult; Aldosterone; Circadian Rhythm; Humans; Hypertension; Male; Middle Aged; Renin

1986
Excessive sodium retention as a characteristic of salt-sensitive hypertension.
    The American journal of the medical sciences, 1986, Volume: 292, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure; Blood Volume; Body Weight; Creatinine; Female; Humans; Hypertens

1986
Suppression of plasma renin and aldosterone in stress-salt hypertension in dogs.
    The American journal of physiology, 1986, Volume: 251, Issue:1 Pt 2

    Topics: Aldosterone; Animals; Avoidance Learning; Cardiovascular System; Dogs; Female; Heart Rate; Hypertens

1986
The syndrome of hypertension and hyperkalaemia with normal GFR. A unique pathophysiological mechanism for hypertension?
    Clinical and experimental pharmacology & physiology, 1986, Volume: 13, Issue:4

    Topics: Adult; Aldosterone; Diet; Female; Glomerular Filtration Rate; Humans; Hyperkalemia; Hypertension; Ki

1986
Lack of effect of nifedipine on counterregulatory mechanisms in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:8

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Catecholamines; Female; Glomerular Filtration Rate; Humans

1986
Is single oral administration of captopril beneficial in screening for primary aldosteronism?
    American heart journal, 1986, Volume: 112, Issue:2

    Topics: Adult; Aldosterone; Angiotensin II; Captopril; Diagnosis, Differential; Diet, Sodium-Restricted; Hum

1986
Central renin-angiotensin system and the pathogenesis of DOCA-salt hypertension in rats.
    The American journal of physiology, 1986, Volume: 251, Issue:2 Pt 2

    Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain; Captopril; Desoxycortico

1986
The effect of 8 weeks treatment with the calcium antagonist felodipine on blood pressure, heart rate, working capacity, plasma renin activity, plasma angiotensin II, urinary catecholamines and aldosterone in patients with essential hypertension.
    British journal of clinical pharmacology, 1986, Volume: 21, Issue:6

    Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Catecholamines; Felodipine; Heart Rate;

1986
Renal prostaglandin E in sustained severe hypertension.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1986, Volume: 85, Issue:4

    Topics: Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Prostag

1986
Mineralocorticoid-induced kaliuresis in type-II pseudohypoaldosteronism.
    The American journal of the medical sciences, 1986, Volume: 292, Issue:4

    Topics: Acidosis; Adult; Aldosterone; Benzothiadiazines; Desoxycorticosterone; Diuretics; Humans; Hyperkalem

1986
Renin-angiotensin-aldosterone system: a long-term follow-up study in 17 alpha-hydroxylase deficiency syndrome (17OHDS).
    Clinical and experimental hypertension. Part A, Theory and practice, 1986, Volume: 8, Issue:4-5

    Topics: Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Female; Glucocortic

1986
A case of adrenal tumor producing renin, aldosterone, and sex steroid hormones.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:10

    Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Carcinoma; Female; Gon

1986
Diagnostic value of captopril test in primary aldosteronism.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1986, Volume: 85, Issue:5

    Topics: Adult; Aldosterone; Captopril; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged;

1986
Effects of intravenous administration of a calcium antagonist on prostaglandins and thromboxane in plasma and urine in humans.
    Prostaglandins, leukotrienes, and medicine, 1986, Volume: 23, Issue:2-3

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Blood Pressure; Calcium Channel Blockers; Dinopros

1986
Effects of volume expansion and contraction on potassium homeostasis in normal and hypertensive humans.
    Journal of the American College of Nutrition, 1986, Volume: 5, Issue:4

    Topics: Adult; Aldosterone; Black People; Blood Volume; Creatinine; Diet, Sodium-Restricted; Female; Furosem

1986
Effect of exogenous angiotensin II infusion after one year of captopril therapy in essential hypertension.
    Postgraduate medical journal, 1986, Volume: 62 Suppl 1

    Topics: Adult; Aldosterone; Angiotensin II; Captopril; Female; Humans; Hypertension; Male; Renin; Time Facto

1986
Systemic systolic hypertension in the elderly: correlation of hemodynamics, plasma volume, renin, aldosterone, urinary metanephrines and response to thiazide therapy.
    The American journal of cardiology, 1986, Nov-01, Volume: 58, Issue:10

    Topics: Aged; Aged, 80 and over; Aldosterone; Epinephrine; Hemodynamics; Humans; Hydrochlorothiazide; Hypert

1986
[Decreased activity of the renal vasodilation and natriuretic system in normotensive men with a familial history of essential hypertension and decreased Na+, K+-cotransport in erythrocytes].
    Casopis lekaru ceskych, 1986, Oct-17, Volume: 125, Issue:41-42

    Topics: Adult; Aldosterone; Carrier Proteins; Erythrocytes; Humans; Hydrocortisone; Hypertension; Kallikrein

1986
Long term evolution of glucocorticoid-suppressible hyperaldosteronism.
    The Journal of clinical endocrinology and metabolism, 1987, Volume: 64, Issue:1

    Topics: Adolescent; Aldosterone; Dexamethasone; Humans; Hyperaldosteronism; Hypertension; Male; Posture; Ren

1987
Plasma aldosterone-plasma renin activity ratio. A simple test to identify patients with primary aldosteronism.
    Acta endocrinologica, 1986, Volume: 113, Issue:4

    Topics: Adult; Aged; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension;

1986
Suppression of adrenal renin in Dahl salt-sensitive rats.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:12

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex; Aldosterone; Animals; Diet, Sodium-Restricted; Femal

1986
Circadian rhythm of plasma renin activity in older normal and essential hypertensive men: relation with inactive renin, aldosterone, cortisol and REM sleep.
    Journal of hypertension, 1986, Volume: 4, Issue:5

    Topics: Aging; Aldosterone; Angiotensinogen; Circadian Rhythm; Enzyme Precursors; Humans; Hydrocortisone; Hy

1986
The renin-angiotensin system is not responsible for hypertension following coronary artery bypass grafting.
    The Annals of thoracic surgery, 1987, Volume: 43, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Cardiopulmonary Bypass; Hemodynamics; Humans; Hypertension; Midd

1987
The effects of acebutolol alone and in combination with furosemide or hydralazine in experimentally induced hypertensive G-minipigs.
    Jikken dobutsu. Experimental animals, 1986, Volume: 35, Issue:4

    Topics: Acebutolol; Aldosterone; Animals; Drug Therapy, Combination; Female; Furosemide; Heart Rate; Hydrala

1986
An abnormal response of the adrenal cortex to insulin: glucose in essential hypertension.
    Journal of clinical hypertension, 1986, Volume: 2, Issue:4

    Topics: Adrenal Cortex; Aldosterone; Bendroflumethiazide; Blood Pressure; Glucose; Humans; Hydrocortisone; H

1986
Thiazide induced hypotension: the role of plasma volume reduction and the urinary kallikrein system.
    Advances in experimental medicine and biology, 1986, Volume: 198 Pt B

    Topics: Aldosterone; Blood Pressure; Humans; Hydrochlorothiazide; Hypertension; Hypotension; Kallikreins; Ma

1986
Acute effect of furosemide on renal kallikrein and prostaglandin systems in mild to moderate essential hypertension.
    International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:1

    Topics: Aldosterone; Female; Furosemide; Hemodynamics; Humans; Hypertension; Kallikreins; Male; Middle Aged;

1987
[Level of prostaglandins, cyclic nucleotides, renin and aldosterone in the plasma of patients with essential hypertension].
    Vrachebnoe delo, 1987, Issue:1

    Topics: Adult; Aldosterone; Humans; Hypertension; Middle Aged; Nucleotides, Cyclic; Prostaglandins; Renin

1987
System dynamics modeling of renin aldosterone and electrolyte changes induced by furosemide in hypertensive patients.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1987, Volume: 86, Issue:1

    Topics: Adult; Aldosterone; Computers; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Models,

1987
Natriuresis and the renin axis in sodium-sensitive man.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1986, Volume: 4, Issue:5

    Topics: Aldosterone; Blood Pressure; Drug Resistance; Extracellular Space; Furosemide; Humans; Hypertension;

1986
Influence of genetic variance on sodium sensitivity of blood pressure.
    Klinische Wochenschrift, 1987, Feb-02, Volume: 65, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Diseases in Twins; Female;

1987
Elevated urinary 19-Nor-deoxycorticosterone glucuronide in Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 1987, Volume: 64, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Aldosterone; Carcinoma; Cushing Syndrome; Desoxycort

1987
Acute haemodynamic and humoral responses to felodipine and metoprolol in mild hypertension.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:1

    Topics: Adult; Aldosterone; Antihypertensive Agents; Calcium Channel Blockers; Catecholamines; Drug Therapy,

1987
[Effect of treatment with pindolol on the renin-angiotensin-aldosterone system, kidney function and electrolyte balance in patients with primary arterial hypertension].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1986, Dec-01, Volume: 41, Issue:48

    Topics: Adolescent; Adult; Aldosterone; Humans; Hypertension; Kidney; Male; Middle Aged; Pindolol; Renin-Ang

1986
[Determination of pregnancy plasma angiotensin II and aldosterone level in hypertensive states].
    Zhonghua fu chan ke za zhi, 1987, Volume: 22, Issue:1

    Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardi

1987
[Studies on the significance of 17 alpha,20 alpha-dihydroxy-4-pregnen-3-one (17 alpha,20 alpha-P) in pregnancy induced hypertension (PIH) and its site of production].
    Nihon Sanka Fujinka Gakkai zasshi, 1987, Volume: 39, Issue:5

    Topics: Aldosterone; Female; Fetal Blood; Humans; Hydroxyprogesterones; Hypertension; In Vitro Techniques; I

1987
Calcium, the renin-aldosterone system, and the hypotensive response to nifedipine.
    Hypertension (Dallas, Tex. : 1979), 1987, Volume: 10, Issue:3

    Topics: Aldosterone; Blood Pressure; Calcium; Humans; Hypertension; Nifedipine; Renin-Angiotensin System

1987
Bootstrapped potential circadian harbingers if not determinants of cardiovascular risk.
    Progress in clinical and biological research, 1987, Volume: 227B

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Circadian Rhythm; Female; Humans; Hydrocortisone; Hy

1987
Central role for sodium in the pathogenesis of blood pressure changes independent of angiotensin, aldosterone and catecholamines in type 1 (insulin-dependent) diabetes mellitus.
    Diabetologia, 1987, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Diabetes Mellitus, Typ

1987
[Role of renal dopamine receptor in the pathogenesis of hypertension after sodium loading].
    Nihon Naibunpi Gakkai zasshi, 1986, Jan-20, Volume: 62, Issue:1

    Topics: Aldosterone; Animals; Dopamine; Hypertension; Kidney; Male; Rats; Rats, Inbred Strains; Receptors, D

1986
Abnormal vasopressin and aldosterone response to furosemide in essential hypertension.
    Acta medica Scandinavica, 1986, Volume: 219, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Electrolytes; Female; Furosemide; Humans;

1986
Role of sulfate conjugation of catecholamines in blood pressure regulation.
    Federation proceedings, 1986, Volume: 45, Issue:8

    Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Aldosterone; Animals; Blood Pressure; Catecholamines; Dogs;

1986
[Effect of urapidil on adrenal cortex activity and prolactin secretion in patients with idiopathic hypertension].
    Polskie Archiwum Medycyny Wewnetrznej, 1986, Volume: 75, Issue:1

    Topics: Adrenal Cortex; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged;

1986
[Clinical significance and characteristics of the radioimmunologic determination of aldosterone levels in serum (plasma)].
    Srpski arhiv za celokupno lekarstvo, 1986, Volume: 114, Issue:2

    Topics: Adolescent; Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension

1986
HPLC isolation and GC-MS characterization of a compound strongly cross reacting with tetrahydroaldosterone antiserum.
    Journal of steroid biochemistry, 1986, Volume: 25, Issue:1

    Topics: Aldosterone; Chromatography, High Pressure Liquid; Chromatography, Paper; Cross Reactions; Gas Chrom

1986
[Fundamental evaluation of aldosterone by aldosterone radioimmunoassay kit II].
    Radioisotopes, 1986, Volume: 35, Issue:4

    Topics: Aldosterone; Evaluation Studies as Topic; Humans; Hyperaldosteronism; Hypertension; Radioimmunoassay

1986
Abnormal renal sodium handling in essential hypertension. Relation to failure of renal and adrenal modulation of responses to angiotensin II.
    The American journal of medicine, 1986, Volume: 81, Issue:3

    Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Humans;

1986
A simple method for definition of incomplete suppression of aldosterone and its association with hypertension and hypokalaemia in man.
    Clinical science (London, England : 1979), 1986, Volume: 71, Issue:4

    Topics: Aged; Aldosterone; Diet, Sodium-Restricted; Female; Humans; Hyperaldosteronism; Hypertension; Hypoka

1986
[Diagnosis of primary aldosteronism].
    Deutsche medizinische Wochenschrift (1946), 1986, Sep-26, Volume: 111, Issue:39

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Diagnosis, Differential

1986
[How do gestational hormones modify sodium balance? Contribution to the genesis of "pill hypertension"].
    Fortschritte der Medizin, 1986, Aug-07, Volume: 104, Issue:29

    Topics: Aldosterone; Contraceptives, Oral, Hormonal; Female; Humans; Hypertension; Progesterone; Water-Elect

1986
Effect of sodium balance and calcium channel-blocking drugs on plasma aldosterone responses to infusion of angiotensin II in normal subjects and patients with essential hypertension.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 63, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Calcium; Calcium Channel Blockers; Diet, Sodium-Restricted; Dilt

1986
A physico-chemical comparison of aortic receptors in rat hypertension models.
    Life sciences, 1986, Oct-06, Volume: 39, Issue:14

    Topics: Aldosterone; Animals; Aorta; Binding Sites; Chromatography, DEAE-Cellulose; Hypertension; Male; Musc

1986
[Changes in sodium metabolism in essential hypertension patients].
    Vutreshni bolesti, 1986, Volume: 25, Issue:3

    Topics: Adult; Aldosterone; Blood Volume; Cardiac Output; Female; Humans; Hypertension; Male; Middle Aged; P

1986
Reversal of changes in metabolism and calcium sensitivity in aortas of rats recovered from aldosterone-salt hypertension.
    Blood vessels, 1986, Volume: 23, Issue:4-5

    Topics: Aldosterone; Animals; Aorta, Thoracic; Calcium; Energy Metabolism; Hypertension; Rats; Rats, Inbred

1986
[Diagnostic possibilities of MR-tomography of the adrenals of patients with essential hypertension].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:11

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hypertension; Magnetic Resonance Spectr

1986
The effects of 19-nor-aldosterone on blood pressure of adrenalectomized spontaneously hypertensive rats.
    Steroids, 1985, Volume: 46, Issue:6

    Topics: Adrenalectomy; Aldosterone; Animals; Blood Pressure; Hypertension; Rats; Rats, Inbred SHR; Rats, Inb

1985
Dopaminergic regulation of plasma aldosterone secretion in hypertensive patients.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1985, Volume: 84, Issue:11

    Topics: Adult; Age Factors; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Re

1985
Urinary free 19-nor-deoxycorticosterone and deoxycorticosterone in human hypertension.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 60, Issue:2

    Topics: Adult; Aged; Aldosterone; Desoxycorticosterone; Diet, Sodium-Restricted; Female; Humans; Hypertensio

1985
Dopamine reduces aldosterone and 18-hydroxycorticosterone response to angiotensin II in patients with essential low-renin hypertension and idiopathic hyperaldosteronism.
    Clinical science (London, England : 1979), 1985, Volume: 68, Issue:3

    Topics: 18-Hydroxycorticosterone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Corticosterone; Depres

1985
[Tetanic spasms, arterial hypertension and hypokalemia].
    Der Internist, 1985, Volume: 26, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Female; Humans; Hypertension

1985
Calcium metabolism and parathyroid function in primary aldosteronism.
    The American journal of medicine, 1985, Volume: 78, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Blood Pressure; Calcium;

1985
Salt-induced hypertension in the 'Sabra' rat strain: influence of nifedipine treatment.
    Clinical science (London, England : 1979), 1985, Volume: 68, Issue:5

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Hypertension; Male; Myocardium; Nifedipine; Organ

1985
[Plasma renin activity, plasma aldosterone concentration in the differential diagnosis of curable forms of secondary hypertension].
    Zhonghua nei ke za zhi, 1985, Volume: 24, Issue:1

    Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Angiotensin II; Diagnosis, Differential; Humans; Hyper

1985
Aldosterone response to modulation of potassium in patients on dialysis or with essential hypertension.
    Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress, 1985, Volume: 21

    Topics: Adult; Aldosterone; Glucose; Humans; Hydrocortisone; Hypertension; Insulin; Potassium; Renal Dialysi

1985
High prevalence of cardiovascular diseases and enhanced activity of the renin-angiotensin system in psoriatic patients.
    Acta cardiologica, 1985, Volume: 40, Issue:2

    Topics: Aldosterone; Cardiovascular Diseases; Coronary Disease; Diabetes Mellitus; Humans; Hypercholesterole

1985
Body-sodium and blood volume in a patient with licorice-induced hypertension.
    Journal of hypertension, 1985, Volume: 3, Issue:1

    Topics: Aged; Aldosterone; Blood Volume; Diagnosis, Differential; Glycyrrhetinic Acid; Glycyrrhiza; Glycyrrh

1985
Effects of orally administered glandular kallikrein on urinary kallikrein and prostaglandin excretion, plasma immunoreactive prostanoids and platelet aggregation in essential hypertension.
    Klinische Wochenschrift, 1985, Apr-01, Volume: 63, Issue:7

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Blood Pressure; Female; Humans; Hypertension; Kall

1985
Captopril before and after spironolactone therapy in primary aldosteronism. Pathogenetic and therapeutical aspects.
    Klinische Wochenschrift, 1985, Apr-15, Volume: 63, Issue:8

    Topics: Aldosterone; Blood Pressure; Captopril; Drug Therapy, Combination; Humans; Hypertension; Potassium;

1985
Is the antihypertensive effect of muzolimine due to volume depletion?
    Zeitschrift fur Kardiologie, 1985, Volume: 74 Suppl 2

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Volume; Chronic Disease; Creatini

1985
Aldosterone studies in obese patients with hypertension.
    The American journal of the medical sciences, 1985, Volume: 289, Issue:6

    Topics: Aldosterone; Blood Pressure; Body Weight; Diet, Reducing; Humans; Hypertension; Natriuresis; Obesity

1985
The state of the renin-angiotensin-aldosterone system in various clinical forms of hypertension in aging.
    Archives of gerontology and geriatrics, 1985, Volume: 4, Issue:1

    Topics: Adult; Aged; Aging; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angio

1985
[Hypertension in the elderly: pathophysiological comparison between subjects with sustained hypertension and with transient hypertension on admission].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1985, Volume: 22, Issue:2

    Topics: Aged; Aldosterone; Female; Hospitalization; Humans; Hypertension; Male; Middle Aged; Patient Admissi

1985
[Clinical evaluation of penbutolol (Hoe 893d) (beta adrenergic blocker), alone and in combination with hydrochlorothiazide, in the treatment of arterial hypertension. II. Effect on plasma electrolytes, renal function, plasma renin and aldosterone activity
    Medicina clinica, 1985, Jun-08, Volume: 85, Issue:2

    Topics: Aldosterone; Antihypertensive Agents; Drug Therapy, Combination; Electrolytes; Humans; Hydrochloroth

1985
Effect of a calcium antagonist: verapamil on resting blood pressure and pressor response to dynamic exercise.
    Acta cardiologica, 1985, Volume: 40, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Female; Heart Rate; Humans; Hypertension; Male;

1985
Urinary excretion of kallikrein before and after operation for aldosterone-producing adenoma.
    Acta medica Scandinavica, 1985, Volume: 217, Issue:5

    Topics: Adenoma; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Kallikreins; Male; Mi

1985
Essential hypertension: a metabolic cause? A hypothesis.
    Angiology, 1985, Volume: 36, Issue:5

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Calcium; Captopril; Female; Humans; Hydrochlorothiazide; H

1985
Morphological changes in the adrenal cortex in different variants of low-renin hyperaldosteronism. Comparison with the functional state of certain hormonal systems.
    Cor et vasa, 1985, Volume: 27, Issue:2-3

    Topics: Adenoma; Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Aldosterone; Hu

1985
[Results of the surgical management of primary aldosteronism based on a retrospective analysis of preoperative diagnosis and morphology of the adrenal gland].
    Orvosi hetilap, 1985, Sep-01, Volume: 126, Issue:35

    Topics: Adrenal Glands; Adrenalectomy; Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Corticosterone

1985
Resistance to captopril in hypertension of coarctation of the aorta.
    International journal of cardiology, 1985, Volume: 9, Issue:1

    Topics: Adult; Aldosterone; Aortic Coarctation; Captopril; Drug Resistance; Humans; Hypertension; Middle Age

1985
A study of urinary sodium and potassium excretion rates among urban and rural Zulus and Indians.
    Journal of hypertension, 1985, Volume: 3, Issue:4

    Topics: Adult; Age Factors; Aldosterone; Black People; Blood Pressure; Female; Humans; Hypertension; Kinetic

1985
[Changes in reactivity of the renin-angiotensin-aldosterone system in old age as a risk factor in the development of hypertension].
    Kardiologiia, 1985, Volume: 25, Issue:6

    Topics: Adult; Aged; Aging; Aldosterone; Angiotensin II; Homeostasis; Humans; Hypertension; Hypothalamo-Hypo

1985
[Role of hormonal factors in the etiology of juvenile arterial hypertension].
    Kardiologiia, 1985, Volume: 25, Issue:6

    Topics: Adolescent; Adult; Aldosterone; Blood Pressure; Hormones; Humans; Hydrocortisone; Hypertension; Male

1985
Head out water immersion (WI) induced endocrine alterations in hypertensive patients.
    Przeglad lekarski, 1985, Volume: 42, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Humans; Hypertension; Immersion; Plasma Volume; Renin; Vasopress

1985
Is the renin-angiotensin-aldosterone system (RAAS) related to vasopressin (AVP) secretion in patients with essential hypertension.
    Przeglad lekarski, 1985, Volume: 42, Issue:3

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Male; Renin; Renin-Angiotensin System; Vasopressin

1985
Adrenalectomy in primary aldosteronism: a long-term follow-up study.
    Cardiology, 1985, Volume: 72 Suppl 1

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Blo

1985
Pathogenetic aspects of hypertension in Cushing's syndrome.
    Cardiology, 1985, Volume: 72 Suppl 1

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensinogen; Blood Pressure; Child; Circadian Rhythm; Cush

1985
Effects of san-huang-hsieh-hsin-tang on sympathetic activity, plasma renin, and plasma aldosterone.
    Clinical therapeutics, 1985, Volume: 7, Issue:5

    Topics: Aldosterone; Humans; Hypertension; Medicine, Chinese Traditional; Medicine, East Asian Traditional;

1985
Clinical evaluation of the captopril screening test for primary aldosteronism.
    Japanese heart journal, 1985, Volume: 26, Issue:4

    Topics: Adult; Aldosterone; Captopril; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal

1985
Two possible mechanisms for alcohol associated hypertension.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1985, Volume: 176

    Topics: Adult; Alcohol Drinking; Alcoholism; Aldosterone; Blood Pressure; Double-Blind Method; Ethanol; Huma

1985
Alcohol withdrawal and hypertension: evidence for a kidney abnormality.
    Clinical science (London, England : 1979), 1985, Volume: 69, Issue:2

    Topics: Alcoholism; Aldosterone; Humans; Hydrocortisone; Hypertension; Kidney; Natriuresis; Renin; Substance

1985
Effects of diltiazem on hormonal and hemodynamic responses to lower body negative pressure and tilt in patients with mild to moderate systemic hypertension.
    The American journal of cardiology, 1985, Dec-06, Volume: 56, Issue:16

    Topics: Adult; Aged; Aldosterone; Benzazepines; Blood Pressure; Diltiazem; Forearm; Heart Rate; Hemodynamics

1985
Angiotensin-induced hypertension in conscious dogs: biochemical parameters and baroreceptor reflex.
    Cardiovascular research, 1985, Volume: 19, Issue:11

    Topics: Aldosterone; Angiotensin II; Animals; Body Weight; Consciousness; Disease Models, Animal; Dogs; Fema

1985
The diagnostic value of the 24 hour integrated concentration of plasma aldosterone.
    Clinical and experimental hypertension. Part A, Theory and practice, 1985, Volume: 7, Issue:9

    Topics: Adolescent; Adult; Aged; Aldosterone; Analysis of Variance; Child; Diagnosis, Differential; Evaluati

1985
Cardiovascular, baroreflex and humoral responses in hypertensive patients during nicardipine therapy.
    European journal of clinical pharmacology, 1985, Volume: 29, Issue:3

    Topics: Adult; Aldosterone; Carotid Arteries; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle A

1985
[Studies on the pathophysiology of pregnancy induced hypertension--endocrinological analysis by the method of angiotensin II and NaCl loading].
    Nihon Sanka Fujinka Gakkai zasshi, 1985, Volume: 37, Issue:11

    Topics: Aldosterone; Angiotensin II; Bradykinin; Female; Humans; Hypertension; Kallikreins; Pregnancy; Pregn

1985
[Central hemodynamic function and the metabolic electrolyte ratio of patients with hypertension and hereditary disposition].
    Terapevticheskii arkhiv, 1985, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Catecholamines; Chronic Disease; Disease Susceptibility

1985
Body sodium-blood volume state, aldosterone, and cardiovascular responsiveness after calcium entry blockade with nifedipine.
    Kidney international, 1985, Volume: 28, Issue:4

    Topics: Aged; Aldosterone; Angiotensin II; Blood Volume; Calcium; Chlorthalidone; Drug Therapy, Combination;

1985
The role of urinary kininogen in the regulation of kinin generation.
    Kidney international, 1985, Volume: 28, Issue:6

    Topics: Aldosterone; Blood Pressure; Creatinine; Diuresis; Humans; Hypertension; Kallikreins; Kidney Failure

1985
The contribution of arterial pressure to the cardiac dysfunction of chronic alcoholism.
    Acta medica Scandinavica. Supplementum, 1985, Volume: 703

    Topics: Adult; Alcoholism; Aldosterone; Blood Pressure; Catecholamines; Echocardiography; Electrolytes; Hear

1985
[Concentration of somatotropic hormone in the blood in arterial hypertension of different origin].
    Kardiologiia, 1985, Volume: 25, Issue:12

    Topics: Adult; Aldosterone; Climacteric; Female; Growth Hormone; Hemodynamics; Humans; Hypertension; Hyperte

1985
Hemodynamic, renal, and hormonal responses to changes in dietary potassium in normotensive and hypertensive man: long-term antihypertensive effect of potassium supplementation in essential hypertension.
    Klinische Wochenschrift, 1985, Apr-15, Volume: 63, Issue:8

    Topics: Adult; Aldosterone; Blood Pressure; Creatinine; Diet, Sodium-Restricted; Epinephrine; Female; Hormon

1985
[Acute effect of nifedipine on arterial pressure and the renin-angiotensin system in healthy subjects and hypertensives].
    Archives des maladies du coeur et des vaisseaux, 1985, Volume: 78 Spec No

    Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male

1985
Intracerebroventricular infusion of aldosterone induces hypertension in rats.
    Endocrinology, 1986, Volume: 118, Issue:2

    Topics: Aldosterone; Animals; Brain; Cerebral Ventricles; Hypertension; Male; Mineralocorticoid Receptor Ant

1986
Dopaminergic modulation of salt sensitivity in patients with essential hypertension.
    Life sciences, 1986, Mar-10, Volume: 38, Issue:10

    Topics: Aged; Aldosterone; Blood Pressure; Dopamine; Dopamine Antagonists; Epinephrine; Female; Humans; Hype

1986
Alterations in active Na-K transport during mineralocorticoid-salt hypertension in the rat.
    The American journal of physiology, 1986, Volume: 250, Issue:4 Pt 1

    Topics: Aldosterone; Animals; Biological Transport, Active; Chlorides; Desoxycorticosterone; Hypertension; K

1986
The prediction of anatomical morphology of primary aldosteronism using serum 18-hydroxycorticosterone levels.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 60, Issue:1

    Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Corticoster

1985
Calcium sensitivity of isometric force in intact and chemically skinned aortas during the development of aldosterone-salt hypertension in the rat.
    Circulation research, 1985, Volume: 56, Issue:3

    Topics: Aldosterone; Animals; Biological Transport; Blood Pressure; Calcium; Hypertension; Rats

1985
Clinical significance of unconjugated 3 alpha,5 beta-tetrahydroaldosterone and 5 beta-dihydroaldosterone measured by radioimmunoassay.
    Clinical endocrinology, 1985, Volume: 22, Issue:2

    Topics: Aldosterone; Chromatography, Paper; Female; Humans; Hypertension; Male; Radioimmunoassay

1985
[Therapy resistant hypertension].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1985, Apr-23, Volume: 74, Issue:17

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Female; Humans; Hypertension; Middle Aged; Neoplasms,

1985
Plasma immunoreactive gamma melanotropin in patients with idiopathic hyperaldosteronism, aldosterone-producing adenomas, and essential hypertension.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:1

    Topics: Adenoma; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Melanocyte-Stim

1985
The second Sir George Pickering memorial lecture. What regulates whole body autoregulation? Clinical observations.
    Journal of hypertension, 1985, Volume: 3, Issue:2

    Topics: Adult; Aldosterone; Autonomic Nervous System Diseases; Blood Pressure; Body Fluids; Cardiac Output;

1985
Antihypertensive effect of riboflavin analogues in spontaneously hypertensive rats.
    The Journal of laboratory and clinical medicine, 1985, Volume: 106, Issue:2

    Topics: Aldosterone; Animals; Antihypertensive Agents; Flavins; Hydrochlorothiazide; Hypertension; Male; Min

1985
Sodium-dependent hypertension produced by chronic central angiotensin II infusion.
    The American journal of physiology, 1985, Volume: 249, Issue:2 Pt 2

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Water; Drinking; Heart Rat

1985
Diagnostic imaging in hypertension.
    Chest, 1985, Volume: 88, Issue:3 Suppl

    Topics: Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension; Hypertension, Renovascular; Urography

1985
Atrial natriuretic factor: isolation, identification, biological and pharmacological actions.
    Klinische Wochenschrift, 1985, Volume: 63 Suppl 3

    Topics: Aldosterone; Amino Acid Sequence; Animals; Blood Vessels; Heart Atria; Hypertension; Myocardium; Nat

1985
21-Deoxytetrahydroaldosterone excretion in primary hyperaldosteronism.
    Cardiology, 1985, Volume: 72 Suppl 1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Humans; Hyperaldosteronism; Hyperplas

1985
Selective blood sampling in adrenal hypertension.
    Cardiology, 1985, Volume: 72 Suppl 1

    Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Aldosterone; Cushing Syndrome; Epinephrine;

1985
Nicardipine and nifedipine: effects on diuresis and serum aldosterone levels in spontaneously hypertensive rats.
    Proceedings of the Western Pharmacology Society, 1985, Volume: 28

    Topics: Aldosterone; Animals; Blood Pressure; Diuresis; Hypertension; Male; Nicardipine; Nifedipine; Rats; R

1985
[Serum aldosterone level in patients with hypertension during treatment by acupuncture].
    Terapevticheskii arkhiv, 1985, Volume: 57, Issue:10

    Topics: Acupuncture Therapy; Adult; Aldosterone; Female; Follow-Up Studies; Humans; Hyperaldosteronism; Hype

1985
Hypertension in hypothyroidism: arterial pressure and hormone relationships.
    Clinical and experimental hypertension. Part A, Theory and practice, 1985, Volume: 7, Issue:11

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Epinephrine; Female; Heart Rate; Humans; Hype

1985
Hypertension with aldosterone excess and low plasma-renin: preoperative distinction between patients with and without adrenocortical tumour.
    Lancet (London, England), 1970, Nov-14, Volume: 2, Issue:7681

    Topics: Adenoma; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Age Fac

1970
Apparently isolated excess deoxycorticosterone in hypertension. A variant of the mineralocorticoid-excess syndrome.
    Lancet (London, England), 1972, Aug-05, Volume: 2, Issue:7771

    Topics: 17-Ketosteroids; Adult; Aged; Aldosterone; Chromatography, Gas; Desoxycorticosterone; Dexamethasone;

1972
Plasma renin, renin substrate, angiotensin II, and aldosterone in hypertensive disease of pregnancy.
    Lancet (London, England), 1973, Feb-10, Volume: 1, Issue:7798

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Estrogens; Female; Gestational Age; Humans; Hypertensio

1973
Plasma-aldosterone during oral-contraceptive therapy.
    Lancet (London, England), 1973, Jun-02, Volume: 1, Issue:7814

    Topics: Acetates; Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Contraceptive

1973
Mineralocorticoids and rectal potential difference.
    Lancet (London, England), 1973, Sep-22, Volume: 2, Issue:7830

    Topics: Aldosterone; Biological Transport, Active; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Me

1973
Editorial: Sodium and the pressor role of angiotensin.
    Lancet (London, England), 1973, Nov-10, Volume: 2, Issue:7837

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Hypertension,

1973
Body-fluid volume in low-renin hypertension.
    Lancet (London, England), 1974, Aug-10, Volume: 2, Issue:7876

    Topics: Adult; Aldosterone; Blood Pressure; Body Height; Body Surface Area; Body Weight; Extracellular Space

1974
Renin and hypertension in childhood.
    Archives of disease in childhood, 1974, Volume: 49, Issue:11

    Topics: Aldosterone; Alpha-Globulins; Angiotensin II; Child; Child, Preschool; Humans; Hypertension; Hyperte

1974
Proceedings: Mode of action of beta-adrenergic receptor blocking drugs in hypertension.
    Scottish medical journal, 1974, Volume: 19, Issue:1

    Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Brain; Cardiac Output; Humans; Hypertensio

1974
Sympathectomy for hypertension.
    American journal of surgery, 1974, Volume: 127, Issue:5

    Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Diuretics; Guanethidine; Humans; Hypertens

1974
[Neurohumoral aspects of myocardial infarct and its complications].
    Kardiologiia, 1974, Volume: 14, Issue:4

    Topics: 17-Ketosteroids; Adrenal Glands; Adult; Aged; Aldosterone; Epinephrine; Female; Heart Failure; Hemod

1974
[Essential hypertension: Renin and aldosterone, key to pathogeny and therapy?].
    Schweizerische medizinische Wochenschrift, 1974, Jul-20, Volume: 104, Issue:29

    Topics: Adrenergic beta-Antagonists; Aldosterone; Autonomic Nervous System; Blood Volume; Diuretics; Hemodyn

1974
The influence of a heparin-like compound on hypertension, electrolytes and aldosterone in man.
    Transactions of the American Clinical and Climatological Association, 1966, Volume: 77

    Topics: Adult; Aldosterone; Blood; Electrolytes; Ephedrine; Heparinoids; Humans; Hypertension; Middle Aged;

1966
Renin and angiotensin.
    Lancet (London, England), 1968, Aug-10, Volume: 2, Issue:7563

    Topics: Addison Disease; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Kidney; Potassiu

1968
Clinical investigation of the effects of adrenal corticosteroid excess on the colon.
    Lancet (London, England), 1969, Mar-01, Volume: 1, Issue:7592

    Topics: Addison Disease; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Adult; Aldosterone; Colon; C

1969
Possible mechanism of action for aldosterone-induced hypertension.
    Lancet (London, England), 1970, May-09, Volume: 1, Issue:7654

    Topics: Aldosterone; Animals; Blood Pressure; Carotid Sinus; Humans; Hyperaldosteronism; Hypertension; Hyper

1970
The influence of a heparin-like compound on hypertension, electrolytes and aldosterone in man.
    Canadian Medical Association journal, 1966, May-28, Volume: 94, Issue:22

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aldosterone; Blood Pressure; Female; Glycosaminoglycans;

1966
Co-existing aldosterone-producing adrenal tumor (aldosteronoma) and bilateral renovascular lesions.
    The Journal of urology, 1969, Volume: 101, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Angiography; Blood Pressure; Carbon Di

1969
Essential hypertension: renin and aldosterone, heart attack and stroke.
    The New England journal of medicine, 1972, Mar-02, Volume: 286, Issue:9

    Topics: Adult; Aldosterone; Cardiomegaly; Cerebrovascular Disorders; Female; Humans; Hypertension; Male; Mid

1972
Excretion of conjugated 11-deoxy-17-ketosteroids in "essential" hypertension.
    Canadian journal of biochemistry, 1972, Volume: 50, Issue:12

    Topics: 17-Ketosteroids; Adult; Age Factors; Aged; Aldosterone; Androstenes; Androsterone; Blood Pressure; C

1972
The vascular reactivity to vasoactive substances and the electrolyte contents in arterial walls.
    The Tohoku journal of experimental medicine, 1965, Sep-25, Volume: 86, Issue:4

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Arteries; Blood Pressure; Carbon Tetrachloride

1965
[Studies on the renin-angiotensin-aldosterone system, especially their roles in the humoral regulating system and the cause of hypertension].
    Japanese circulation journal, 1965, Volume: 29, Issue:12

    Topics: Aldosterone; Angiotensin II; Animals; Dogs; Hypertension; Rats; Renin

1965
On the role of renin-angiotensin system with special relation to aldosterone for the etiology of hypertension.
    Japanese circulation journal, 1966, Volume: 30, Issue:2

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood; Hyperaldosteronism; Hypertension; In Vit

1966
On the humoral factors in arterial hypertension.
    Japanese circulation journal, 1966, Volume: 30, Issue:2

    Topics: Aldosterone; Angiotensin II; Blood; Humans; Hypertension; Renin; Urine

1966
[Behavior of urinary aldosterone and electrolytes during infusion of angiotensin II in normal, essential and renovascular hypertensive subjects].
    Folia endocrinologica, 1965, Volume: 18, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; In Vitro Techniques; Male; Urine;

1965
[Aldosteronism].
    Nihon Naibunpi Gakkai zasshi, 1965, Oct-20, Volume: 41, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Animals; Edema; Female; Humans

1965
[Angiotensin intradermoreaction in patients with liver cirrhosis in the ascitic phase. Results and interpretation in relation to the pathogenesis of the altered hydrosaline metabolism in cirrhogenic liver diseases].
    Minerva medica, 1966, Dec-19, Volume: 57, Issue:101

    Topics: Aldosterone; Angiotensin II; Ascites; Diabetes Insipidus; Heart Failure; Humans; Hypertension; Jaund

1966
Renal renin in unilaterally nephrectomized hypertensive rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 118, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Female; Hypertension; Juxtaglomerular Apparatus; Kidney; Kidne

1965
[Study on corticosterone secretion rate with reference to normal and hypertensive subjects].
    Nihon Naibunpi Gakkai zasshi, 1966, Oct-20, Volume: 42, Issue:7

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Aldosterone; Body Constitut

1966
Renin-angiotensin-aldosterone system during chronic thiazide therapy of benign hypertension.
    Circulation, 1968, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hydrochlorothiazide; Hypertens

1968
Effect of corticotropin on aldosterone excretion and plasma renin in normal subjects, in essential hypertension and in primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angioten

1968
Effects of glucocorticoid administration on aldosterone excretion and plasma renin in normal subjects, in essential hypertension and in primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Dexameth

1968
[Renin and aldosterone in human arterial hypertension (excluding Conn's syndrome)].
    Pathologie et biologie, 1965, Volume: 13, Issue:21

    Topics: Adult; Aldosterone; Angiotensin II; Diagnosis, Differential; Diet, Sodium-Restricted; Female; Humans

1965
[Aldosteronuria in the hypertensive patient with Addison's disease].
    Studii si cercetari de endocrinologie, 1968, Volume: 19, Issue:2

    Topics: Addison Disease; Adrenocorticotropic Hormone; Aged; Aldosterone; Angiotensin II; Female; Humans; Hyp

1968
[Influence of experimental sodium chloride depletion on water-electrolyte metabolism, blood pressure and reaction ability of the vascula system in young hypertonics].
    Zeitschrift fur Kreislaufforschung, 1968, Volume: 57, Issue:7

    Topics: Adult; Age Factors; Aldosterone; Angiotensin II; Blood Vessels; Electrolytes; Erythrocytes; Female;

1968
[The reinin- angiotensin-aldosterone system in essential and renovascular hypertension].
    Pathologie et biologie, 1968, Volume: 16, Issue:9

    Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypertension, Renal; Juxtaglomerul

1968
Aldosterone production after suppression of corticotropic secretory activity.
    Archives of internal medicine, 1968, Volume: 122, Issue:5

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Depression, Chemical; Dexamethasone; Diet,

1968
[Data on the further study of the etiology and pathogenesis of hypertension].
    Kardiologiia, 1967, Volume: 7, Issue:3

    Topics: Adrenocortical Hyperfunction; Aldosterone; Animals; Bradykinin; Brain; Carotid Sinus; Dogs; Endopept

1967
Suppressed plasma renin activity in hypertension.
    Archives of internal medicine, 1969, Volume: 123, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldostero

1969
[The renin, angiotensin and aldosterone system in secondary hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1968, Volume: 26, Issue:11

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin

1968
Studies of hypertension and carbohydrate intolerance associated with Wilms tumor.
    Annals of internal medicine, 1969, Volume: 70, Issue:3

    Topics: Aldosterone; Carbohydrate Metabolism; Female; Glucose Tolerance Test; Humans; Hypertension; Hypokale

1969
Relation of the pituitary to the sodium-retaining effects of adrenal enucleation.
    Endocrinology, 1969, Volume: 84, Issue:5

    Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Animals; Glucocorticoids; H

1969
Studies of plasma renin activity in patients with hypertension.
    Polish medical journal, 1968, Volume: 7, Issue:6

    Topics: Adult; Aldosterone; Angiotensin II; Diagnosis, Differential; Diet, Sodium-Restricted; Female; Humans

1968
[Does the recent knowledge on the renin-angiotensin system have clinical applications?].
    La Presse medicale, 1968, Nov-30, Volume: 76, Issue:47

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Feedback; Humans; Hyperaldosteronism; Hypertension; Jux

1968
[Determination of renin activity and aldosteronuria in 24 hypertensives].
    La Revue lyonnaise de medecine, 1968, Oct-30, Volume: 17, Issue:16

    Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hype

1968
[Renin and angiotensin].
    Actualites pharmacologiques, 1968, Volume: 21

    Topics: Aldosterone; Angiotensin II; Animals; Arteries; Dogs; Humans; Hypertension; Hypertension, Renal; Jux

1968
Medical grand rounds from the University of Alabama Medical Center.
    Southern medical journal, 1969, Volume: 62, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertens

1969
[Dynamic tests of the function of the renin-angiotensin-aldosterone system].
    Vnitrni lekarstvi, 1969, Volume: 15, Issue:2

    Topics: Adrenal Insufficiency; Aldosterone; Angiotensin II; Diagnosis, Differential; Diazoxide; Diet, Sodium

1969
[Plasma renin activity in peripheral venous blood under various stimulation conditions].
    Deutsche medizinische Wochenschrift (1946), 1969, May-16, Volume: 94, Issue:20

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Arteriosclerosis; Blood Pressure; Creat

1969
Quantitative analysis of the pathophysiology of hypertension.
    Circulation research, 1969, Volume: 24, Issue:5 Suppl

    Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Blood Pressure; Blood Vessels; Cardiac Output

1969
Hypertension with inappropriate aldosterone stimulation.
    The New England journal of medicine, 1969, Jul-17, Volume: 281, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II

1969
[Study on the renin-angiotensin-aldosterone system. Effects of sodium restriction and postural changes on plasma renin activity and fluctuation in urinary aldosterone].
    Japanese circulation journal, 1969, Volume: 33, Issue:3

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Chromatography, Thin Layer; Diet, Sodium-Restricted; Hu

1969
The renin-angiotensin system in curable hypertension.
    Modern concepts of cardiovascular disease, 1969, Volume: 38, Issue:4

    Topics: Aldosterone; Angiotensin II; Chemical Phenomena; Chemistry; Feedback; Humans; Hypertension; Renin

1969
Studies of the renin-angiotensin-aldosterone system in patients with hypertension and in normal subjects.
    The American journal of medicine, 1969, Volume: 46, Issue:6

    Topics: Aldosterone; Angiotensin II; Blood Urea Nitrogen; Body Weight; Creatinine; Diet; Diet, Sodium-Restri

1969
Renin-angiotensin-aldosterone system in hypertension. The clinical usefulness of measuring components of thisystem.
    Virginia medical monthly, 1969, Volume: 96, Issue:6

    Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Renin

1969
Hypermineralocorticoid-induced hypertension.
    Medical times, 1969, Volume: 97, Issue:10

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldosterone; Desoxycorticosterone; Humans

1969
Corticosteroid synthesis in adrenal enucleated rats before the onset of hypertension.
    Endocrinology, 1969, Volume: 85, Issue:6

    Topics: Adrenal Glands; Adrenal Medulla; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Animals; B

1969
Hyperaldosteronism in hypertensive congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:12

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenal Rest Tumor; Adr

1969
[Arterial hypertension and inadequate stimulation of aldosterone secretion. A new syndrome].
    La Presse medicale, 1969, Oct-11, Volume: 77, Issue:42

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Corticosterone; Diet, Sodium-Restricted; H

1969
Primary aldosteronism in a hypertensive acromegalic patient.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:10

    Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone

1969
[Hypertension and endocrinology].
    Nihon Ishikai zasshi. Journal of the Japan Medical Association, 1969, Nov-15, Volume: 62, Issue:10

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Angiotensin II; Catecholamines; Cushi

1969
Suppressed plasma renin activity in essential hypertension. Roles of plasma volume, blood pressure, and sympathetic nervous system.
    Annals of internal medicine, 1970, Volume: 72, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Catecholamines; Diet; Epinephrine;

1970
Abnormal responsiveness of the renin aldosterone system to acute stimulation in patients with essential hypertension.
    Annals of internal medicine, 1970, Volume: 72, Issue:3

    Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Bloodletting; Diuretics

1970
Aldosteronism in hypertensive disease.
    Medical times, 1970, Volume: 98, Issue:3

    Topics: Adrenal Gland Diseases; Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Potas

1970
[A case of arterial hypertension imputable to an estroprogestational contraceptive. Implication of the renin-angiotensin-aldosterone system].
    Journal d'urologie et de nephrologie, 1969, Volume: 75, Issue:12

    Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Estrogens; Female; Humans; Hyperaldosteron

1969
Aldosterone, angiotensin, and hypertension.
    British medical journal, 1970, Mar-28, Volume: 1, Issue:5699

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension

1970
Hypertension in young females receiving anovulatory steroids.
    Annals of surgery, 1970, Volume: 171, Issue:5

    Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Drug Hypersensitivity; Female; Humans; Hyp

1970
The pathophysiology and bio-assay of the renin-angiotensin system.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1970, Mar-28, Volume: 44, Issue:13

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Biological Assay; Child; Child, Preschool; Female; H

1970
Adrenal cortex, aldosterone, and hypertension. Report of an international workshop.
    Circulation, 1969, Volume: 40, Issue:5

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Female; Humans; Hypertension; Methods; Posture

1969
Abnormally sustained aldosterone secretion during salt loading in patients with various forms of benign hypertension; relation to plasma renin activity.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:7

    Topics: Adolescent; Adrenocortical Hyperfunction; Adult; Aldosterone; Angiotensin II; Contraceptives, Oral;

1970
The influence of potassium administration and of potassium deprivation on plasma renin in normal and hypertensive subjects.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:11

    Topics: Adult; Aldosterone; Angiotensin II; Biological Transport, Active; Blood Pressure; Diet Therapy; Fema

1970
[Endocrine hypertension].
    Munchener medizinische Wochenschrift (1950), 1970, Nov-20, Volume: 112, Issue:47

    Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Aldosterone;

1970
[Importance of renin-angiotensin-aldosterone system in diverse forms of hypertension].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1970, May-19, Volume: 59, Issue:20

    Topics: Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Animals; Contraceptives, Oral; Female; Humans;

1970
The pill, hypertension, and the toxemias of pregnancy.
    American journal of obstetrics and gynecology, 1971, Jan-15, Volume: 109, Issue:2

    Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Edema; Estrogens; Female; Humans; Hypernatremia;

1971
Hypertension, oral contraceptive agents, and conjugated estrogens.
    Annals of internal medicine, 1971, Volume: 74, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Determination; Contraceptives, Or

1971
The etiopathology of hypertension.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 4, Issue:1

    Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Cardiac

1970
A quantitative approach to the study of circulatory abnormality, especially of hypertension.
    Clinical science, 1971, Volume: 40, Issue:2

    Topics: Aldosterone; Angiotensin II; Arteries; Blood Pressure; Body Fluids; Humans; Hypertension; Kidney; Pr

1971
[Clarification of a hypertension].
    Schweizerische medizinische Wochenschrift, 1970, Sep-12, Volume: 100, Issue:37

    Topics: Aldosterone; Angiotensin II; Aortic Coarctation; Blood Pressure Determination; Creatinine; Cushing S

1970
[Oral contraceptives and hypertension].
    Schweizerische medizinische Wochenschrift, 1971, Apr-17, Volume: 101, Issue:15

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Estrogens; Female; Humans; Hypert

1971
On the role of aldosterone to hypertension, especially an extent of its participation.
    Japanese circulation journal, 1971, Volume: 35, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Animals; Blood Pressure; Femal

1971
The role of aldosterone in pathogenesis of arterial hypertension.
    Japanese circulation journal, 1971, Volume: 35, Issue:5

    Topics: Addison Disease; Aldosterone; Angiotensin II; Animals; Arteries; Cushing Syndrome; Fundus Oculi; Hum

1971
Discussion on pathogenesis of hypertension.
    Japanese circulation journal, 1971, Volume: 35, Issue:5

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Potassium; Renin; Sodium

1971
Determination of plasma renin concentration by angiotensin I immunoassay. Diagnotic import of precise measurement of subnormal renin in hyperaldosteronism.
    Circulation research, 1971, Volume: 28, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Hyperfunction; Aldos

1971
[Relationship between the renin-angiotensin-aldosterone system and CNS in the etiology of hypertension].
    Das Deutsche Gesundheitswesen, 1971, Feb-04, Volume: 26, Issue:6

    Topics: Aldosterone; Angiotensin II; Central Nervous System; Humans; Hypertension; Renin; Sympathetic Nervou

1971
Abnormal membrane sodium transport in Liddle's syndrome.
    The Journal of clinical investigation, 1971, Volume: 50, Issue:11

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Biological Transport; Cell Membrane; Child; Erythroc

1971
[Comparative gas chromatographic analysis of the FFA-pattern in the plasma in different models of hypertension in the rat].
    Das Deutsche Gesundheitswesen, 1971, Aug-12, Volume: 26, Issue:33

    Topics: Aldosterone; Angiotensin II; Animals; Chromatography, Gas; Disease Models, Animal; Fatty Acids, None

1971
[Relation of plasma renin activity and aldosterone excretion rate in angiotensin II-test and its diagnostic value in arterial hypertension patients].
    Das Deutsche Gesundheitswesen, 1971, Aug-05, Volume: 26, Issue:32

    Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Methods; Renin; Water-Electrolyte B

1971
[Clinical studies on the relation between aldosterone and various hypertensive and renal diseases. 2. Studies on the effect of synthetic angiotensin II on aldosterone secretion rate].
    Naika hokan. Japanese archives of internal medicine, 1971, Volume: 18, Issue:8

    Topics: Addison Disease; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Injections, Intr

1971
Plasma renin activity and aldosterone secretion in patients with acromegaly.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:1

    Topics: Acromegaly; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Chlorides; Diet,

1972
[Significance of renin-angiotensin system in the development of hypertension--author's comments and viewpoint].
    Saishin igaku. Modern medicine, 1971, Volume: 26, Issue:11

    Topics: Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Renin

1971
[The renin-angiotensin-aldosterone system. Disorders and methods of clinical research].
    Schweizerische medizinische Wochenschrift, 1970, Oct-03, Volume: 100, Issue:40

    Topics: Adrenal Gland Neoplasms; Adrenal Insufficiency; Aldosterone; Angiotensin II; Dexamethasone; Electrol

1970
Control of blood pressure.
    British medical journal, 1972, Apr-01, Volume: 2, Issue:5804

    Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Blood Pressure; Hexamethonium Compounds; Huma

1972
Plasma desoxycorticosterone levels in man with simultaneous measurement of aldosterone, corticosterone, cortisol and 11-deoxycortisol.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:6

    Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Carbon Isotopes; Chromatography, Paper; Co

1972
[Hypertension and hypertensive syndromes].
    Kardiologiia, 1971, Volume: 11, Issue:12

    Topics: Adult; Aldosterone; Angiotensin II; Arteriosclerosis; Glomerulonephritis; Humans; Hypertension; Hype

1971
Drug modification of digital vascular reactivity to vasoactive substances.
    Bibliotheca anatomica, 1969, Volume: 10

    Topics: Aldosterone; Angiotensin II; Benzothiadiazines; Blood Pressure; Dihydroxyphenylalanine; Fingers; Gua

1969
Arterial pressure regulation. Overriding dominance of the kidneys in long-term regulation and in hypertension.
    The American journal of medicine, 1972, Volume: 52, Issue:5

    Topics: Aldosterone; Angiotensin II; Arteries; Blood Pressure; Blood Vessels; Blood Volume; Cardiac Output;

1972
Plasma cortisol and adrenocorticotrophic hormone in normal men and non-pregnant women, normal pregnant women and women with pre-eclampsia.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1972, Volume: 79, Issue:6

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood; Cesarean Section; Circadian

1972
Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin.
    British medical journal, 1972, Jun-24, Volume: 2, Issue:5816

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Blood Pr

1972
Low renin hypertension and the adrenal cortex.
    The New England journal of medicine, 1972, Aug-17, Volume: 287, Issue:7

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Cor

1972
Volume control.
    Folia medica Neerlandica, 1972, Volume: 15, Issue:2

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Glomerular Filtration Rate; Hemodynamics; Humans; Hyper

1972
[Kidney and hypertension].
    Klinische Wochenschrift, 1972, Jul-01, Volume: 50, Issue:13

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Extracellular Space; Humans; Hypertension; Hyp

1972
[Renin-angiotensin-aldosterone system in water-electrolyte homeostasis].
    Medicina interna, 1972, Volume: 24, Issue:5

    Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Electrolytes; Humans; Hyperaldosteronism; Hyp

1972
Oral contraceptive hypertension.
    Postgraduate medicine, 1972, Volume: 52, Issue:3

    Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Estrogens; Female; Humans; Hypertension; Kidney;

1972
Effect of prostaglandin A 1 on renal and adrenal function in man.
    Circulation research, 1972, Volume: 31, Issue:9

    Topics: Adrenal Glands; Aldosterone; Ascites; Blood Pressure; Calcium; Creatinine; Cyclic AMP; Edema; Glomer

1972
The renin-angiotensin-aldosterone system in normotensive and hypertensive patients with acromegaly.
    The New England journal of medicine, 1972, Oct-19, Volume: 287, Issue:16

    Topics: Acromegaly; Adolescent; Adult; Aldosterone; Angiotensin II; Blood Volume; Female; Growth Hormone; Hu

1972
The control of aldosterone secretion in normal and hypertensive man: abnormal renin-aldosterone patterns in low renin hypertension.
    The American journal of medicine, 1972, Volume: 53, Issue:5

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Potassium; Renin; Sodium

1972
Renin, angiotensin II, and adrenal corticosteroid relationships during sodium deprivation and angiotensin infusion in normotensive and hypertensive man.
    Circulation research, 1972, Volume: 31, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Corticosterone; Female;

1972
[Hemodialysis and hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:12

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Kidney Failure, Chronic; Renal Dialysis; Renin

1972
Accelerated hypertension secondary to oral contraceptives.
    The Journal of the Maine Medical Association, 1973, Volume: 64, Issue:3

    Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Estrogens; Female; Humans; Hypertension; Renin

1973
[Essential hypertension: biochemical analysis--selective treatment].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1973, Apr-17, Volume: 62, Issue:16

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Propranolol; Renin; Sodium

1973
Effects of ACTH and salt on blood pressure and steroid secretion in rats.
    Acta physiologica latino americana, 1972, Volume: 22, Issue:4

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Pressure; Corticosterone; D

1972
Plasma volume, extracellular fluid volume and exchangeable sodium concentrations in the New Zealand strain of genetically hypertensive rat.
    Clinical science, 1973, Volume: 44, Issue:4

    Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Chromium Isotopes; Extracellular

1973
Angiotensin, aldosterone and DOC in hypertensive disease of pregnancy.
    Scottish medical journal, 1973, Volume: 18, Issue:2

    Topics: Aldosterone; Angiotensin II; Desoxycorticosterone; Female; Humans; Hypertension; Pregnancy; Pregnanc

1973
Hypertension with adrenal, genital, renal defects, and deafness. A new familial syndrome.
    Archives of internal medicine, 1973, Volume: 131, Issue:4

    Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Aldosterone; Deafness; Female; Glucocort

1973
[Arterial hypertension and mineralocorticoids].
    Folia endocrinologica, 1973, Volume: 26, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Cortisone; Cushing Syndrome; Female

1973
[Oral contraceptives and hypertension].
    Schweizerische medizinische Wochenschrift, 1973, May-19, Volume: 103, Issue:20

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Female; Humans; Hypertension; Ren

1973
Time course of decrease in blood pressure and in blood pressure response to vasopressor agents during pregnancy in the rat.
    Pflugers Archiv : European journal of physiology, 1973, Jul-06, Volume: 341, Issue:3

    Topics: Acetylcholine; Aldosterone; Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Female; H

1973
[Renin-angiotensin-aldosterone system in hyperthyroidism].
    Nihon Naibunpi Gakkai zasshi, 1973, Jun-20, Volume: 49, Issue:6

    Topics: Aldosterone; Angiotensin II; Female; Furosemide; Humans; Hypertension; Hyperthyroidism; Hypopituitar

1973
Editorial: New knowledge of benign essential hypertension.
    Canadian Medical Association journal, 1973, Sep-15, Volume: 109, Issue:6

    Topics: Age Factors; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Ethnicity; Humans

1973
Vasoconstriction-volume analysis for understanding and treating hypertension: the use of renin and aldosterone profiles.
    The American journal of medicine, 1973, Volume: 55, Issue:3

    Topics: Aldosterone; Angiotensin II; Arteries; Blood Pressure; Diuretics; Humans; Hyperaldosteronism; Hypert

1973
The renin axis in causation, prognosis and treatment of hypertensive disease.
    Transactions & studies of the College of Physicians of Philadelphia, 1973, Volume: 41, Issue:2

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Prognosis; Renin

1973
Clinical conference: Essential hypertension: new concepts about mechanisms.
    Annals of internal medicine, 1973, Volume: 79, Issue:3

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Humans; Hydroxycorticos

1973
Altered ion transport in vascular smooth muscle from spontaneously hypertensive rats. Influences of aldosterone, norepinephrine, and angiotensin.
    Circulation research, 1973, Volume: 33, Issue:5

    Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Aorta; Aorta, Thoracic; Blood Pressure; Chlorid

1973
Proceedings: Blueprints for the solution of three endocrinological enigmas. The Sir Henry Dale Lecture for 1973.
    The Journal of endocrinology, 1973, Volume: 59, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Blood Glucose; Ca

1973
Renin-secreting Wilms' tumor with severe hypertension. Report of a case and brief review of renin-secreting tumors.
    Annals of internal medicine, 1973, Volume: 79, Issue:6

    Topics: Aldosterone; Child, Preschool; Diagnosis, Differential; Humans; Hypertension; Kidney; Kidney Neoplas

1973
Systems analysis of arterial pressure regulation and hypertension.
    Annals of biomedical engineering, 1972, Volume: 1, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Arteries; Blood Pressure; Capillary Permeability; Cardiac Outp

1972
Renal function in pregnancy.
    Obstetrics and gynecology annual, 1972, Volume: 1

    Topics: Aldosterone; Angiotensin II; Catecholamines; Estrogens; Female; Glomerular Filtration Rate; Glycosur

1972
[Water and electrolyte imbalance and the renin-angiotensin-aldosterone system].
    Nihon Jinzo Gakkai shi, 1973, Volume: 15, Issue:7

    Topics: Aldosterone; Angiotensin II; Animals; Dogs; Electrolytes; Humans; Hypertension; Male; Middle Aged; P

1973
[Pregnancy toxemia. Recent data].
    La Nouvelle presse medicale, 1974, Jan-12, Volume: 3, Issue:2

    Topics: Aldosterone; Angiotensin II; Disseminated Intravascular Coagulation; Estriol; Female; Fetal Death; F

1974
Hormonal profiling in the diagnosis and treatment of essential hypertension.
    Delaware medical journal, 1974, Volume: 46, Issue:3

    Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Female; Humans; Hyperaldosteronism; Hypert

1974
[Recent contributions to the study of arterial hypertension].
    Revue medicale de Liege, 1974, Mar-15, Volume: 29, Issue:6

    Topics: Aldosterone; Angiotensin II; Endopeptidases; Humans; Hypertension; Hypertension, Malignant; Renin

1974
Plasma renin concentration: comparison of angiotensinase inhibitors and correlation with plasma renin activity and aldosterone.
    The Journal of laboratory and clinical medicine, 1974, Volume: 83, Issue:5

    Topics: Aldosterone; Angiotensin II; Dimercaprol; Humans; Hydrogen-Ion Concentration; Hypertension; Methods;

1974
[Diagnosis and therapy of arterial hypertension. Significance of the renin-angiotensin-aldosterone system in differential diagnosis and therapy].
    Fortschritte der Medizin, 1974, Apr-18, Volume: 92, Issue:11

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Antihypertensive Agents; Diagnosis, Differential; Human

1974
Mineralocorticoid receptors in salt-susceptible and salt-resistant rats.
    Endocrinology, 1974, Volume: 94, Issue:6

    Topics: Aldosterone; Animals; Binding, Competitive; Cell Nucleus; Cytoplasm; Desoxycorticosterone; Female; H

1974
[The evaluation of arterial hypertension (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1974, May-21, Volume: 63, Issue:20

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Blood Sedimentation; Electrocardiography; Humans; Hyper

1974
Response of plasma aldosterone to postural change, diuretica, angiotensin II, sodium restriction or loading and prostaglandin.
    Japanese heart journal, 1973, Volume: 14, Issue:6

    Topics: Adrenocortical Hyperfunction; Aldosterone; Angiotensin II; Ascites; Cushing Syndrome; Diet; Diet, So

1973
[Primary and secondary aldosteronism in hypertension].
    Zeitschrift fur Allgemeinmedizin, 1974, Apr-30, Volume: 50, Issue:12

    Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hype

1974
[Prognosis of hypertension disease and of the system renin-angiotension-aldosteron (author's transl)].
    Ceskoslovenska radiologie, 1974, Volume: 28, Issue:1

    Topics: Aldosterone; Angiotensin II; Arteries; Humans; Hydrocortisone; Hypertension; Prognosis; Radioimmunoa

1974
Plasma aldosterone during haemodialysis in patients with terminal renal failure.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1973, Volume: 10, Issue:0

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Humans; Hydrocortisone; Hy

1973
Decreased response of plasma renin activity to orthostasis in diabetic patients with orthostatic hypotension.
    Diabetes, 1974, Volume: 23, Issue:10

    Topics: Adult; Aldosterone; Amyloidosis; Angiotensin II; Animals; Blood Pressure; Cattle; Diabetes Complicat

1974
[Exchangeable sodium and sodium space in some types of hypertension (author's transl)].
    Casopis lekaru ceskych, 1974, Volume: 113, Issue:39

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Renin; Sodium

1974
Clinical use of renin determinations.
    JAMA, 1974, Dec-02, Volume: 230, Issue:9

    Topics: Aldosterone; Angiotensin II; Blood Volume; Feedback; Humans; Hypertension; Hypertension, Renal; Meth

1974
An angiotensin converting-enzyme inhibitor to identify and treat vasoconstrictor and volume factors in hypertensive patients.
    The New England journal of medicine, 1974, Oct-17, Volume: 291, Issue:16

    Topics: Adolescent; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; B

1974
Editorial: Angiotensin inhibition.
    The New England journal of medicine, 1974, Oct-17, Volume: 291, Issue:16

    Topics: Alanine; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Press

1974
Low renin, "normal" aldosterone and hypertension: circadian rhythm of renin, aldosterone, cortisol and growth hormone.
    The Journal of clinical endocrinology and metabolism, 1974, Volume: 39, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Circadian Rhythm; Female; Growth Hormone; Humans; H

1974
Renin and hypertension.
    Bruxelles medical, 1973, Volume: Spec No, Issue:0

    Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Humans; Hyperaldosteronism; Hypertension; Hype

1973
The adrenal cortex and the kidney.
    Kidney international, 1974, Volume: 6, Issue:5

    Topics: Adrenal Cortex; Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Al

1974
[The effect of oral contraceptives on plasma renin activity and plasma renin substrate concentration (author's transl)].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1974, Volume: 12, Issue:9

    Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Drug Combinations; Ethinyl Estradiol; Feed

1974
Some observations on arterial and venous levels of angiotensin II in man.
    Transactions of the American Clinical and Climatological Association, 1974, Volume: 85

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Creatinine; Female; Humans; Hypertension; Iodine Rad

1974
The prevalence of hypertension in an unselected population, and the frequency of abnormalities of potassium, angiotensin II and aldosterone in hypertensive subjects.
    Acta clinica Belgica, 1974, Volume: 29, Issue:5

    Topics: Aldosterone; Angiotensin II; Female; Health Surveys; Humans; Hypertension; Hypokalemia; Male; Middle

1974
[Experimental perspectives on the pathogenesis of essential arterial hypertension].
    Recenti progressi in medicina, 1974, Volume: 57, Issue:6

    Topics: Aldosterone; Angiotensin II; Animals; Anxiety; Blood Coagulation; Epinephrine; Fibrinolysis; Heart R

1974
[Proceedings: Plasma aldosterone response to angiotensin injection in essential hypertension and various other diseases].
    Nihon Naibunpi Gakkai zasshi, 1974, Feb-20, Volume: 50, Issue:2

    Topics: Aldosterone; Angiotensin II; Humans; Hypertension

1974
[Arterial hypertension (author's transl)].
    Revista medica de Chile, 1974, Volume: 102, Issue:11

    Topics: Aldosterone; Angiotensin II; Epinephrine; Humans; Hypertension; Mineralocorticoids; Norepinephrine;

1974
Renin-aldosterone axis in renal transplant patients.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1974, Issue:4

    Topics: Adult; Aldosterone; Angiotensin II; Female; Graft Rejection; Humans; Hypertension; Hypertension, Mal

1974
Treatment of essential hypertension with a new vasodilator in combination with beta-adrenergic blockade.
    The New England journal of medicine, 1970, Mar-05, Volume: 282, Issue:10

    Topics: Adrenergic alpha-Antagonists; Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Cardiac O

1970
[Nephrologic aspects of late gestosis (author's transl)].
    Zeitschrift fur Geburtshilfe und Perinatologie, 1974, Volume: 178, Issue:2

    Topics: Aldosterone; Edema; Female; Hemodynamics; Humans; Hypertension; Kidney Diseases; Pre-Eclampsia; Preg

1974
[Quantitative determination of aldosterone in the urine of patients with hypertension].
    Vutreshni bolesti, 1974, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged

1974
Proceedings: Plasma renin activity and aldosterone concentration in children.
    Archives of disease in childhood, 1974, Volume: 49, Issue:10

    Topics: Age Factors; Aldosterone; Child; Child, Preschool; Humans; Hypertension; Infant; Radioimmunoassay; R

1974
Urinary kallikrein excretion in hypertensive man. Relationships to sodium intake and sodium-retaining steroids.
    Circulation research, 1974, Volume: 35, Issue:6

    Topics: Adult; Aldosterone; Blood Pressure; Diet; Diet, Sodium-Restricted; Fludrocortisone; Humans; Hyperald

1974
Plasma aldosterone in essential hypertension with low renin activity.
    Japanese circulation journal, 1974, Volume: 38, Issue:12

    Topics: Aldosterone; Body Weight; Corticosterone; Cushing Syndrome; Furosemide; Humans; Hydrochlorothiazide;

1974
[Detection of 18-hydroxy-11-desoxycorticosterone and of 2 unknown substances in the urine of hypertensive patients. Isolation of one of these substances].
    Acta clinica Belgica, 1974, Volume: 29, Issue:5

    Topics: Aldosterone; Chromatography, Gas; Chromatography, Paper; Desoxycorticosterone; Female; Humans; Hyper

1974
[Aldosterone excretion and plasma renin activity in patients with essential hypertension and with primary aldosteronism (author's transl)].
    Klinische Wochenschrift, 1974, Oct-15, Volume: 52, Issue:20

    Topics: Adolescent; Adult; Aldosterone; Diet, Sodium-Restricted; Female; Humans; Hyperaldosteronism; Hyperte

1974
[Behavior of plasma aldosterone following sodium reduction and sodium tolerance in primary and renal hypertension].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1974, Volume: 80

    Topics: Aldosterone; Deficiency Diseases; Furosemide; Humans; Hypertension; Hypertension, Renal; Sodium; Sti

1974
[Plasma renin activity and aldosterone excretion in patients with essential hypertension, with hypertension in bilateral adrenal cortex hyperplasia and with aldosterone-producing adrenal cortex adenomas following various sodium tolerance tests].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1974, Volume: 80

    Topics: Adenoma; Adrenal Cortex Function Tests; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldostero

1974
Altered adrenal steroidogenesis in "low renin" essential hypertension.
    Transactions of the Association of American Physicians, 1974, Volume: 87

    Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Animals; Cytosol; Depression, Chemical; Desoxycor

1974
Vascular reactivity in obesity.
    Revue roumaine de medecine (1974), 1974, Volume: 12, Issue:1

    Topics: Adult; Aldosterone; Blood Pressure; Blood Vessels; Catecholamines; Female; Humans; Hydrocortisone; H

1974
Primary aldosteronism, idiopathic aldosteronism and "low-renin" benign essential hypertension. A retrospective study.
    The Netherlands journal of medicine, 1974, Volume: 17, Issue:4-5

    Topics: Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Cerebrovascular Disorders; Female; Humans; Hy

1974
[Proceedings: Plasma aldosterone and 11-deoxycorticosterone (DOC) in normal subjects, endocrinopathic hypertension and essential hypertension].
    Nihon Naibunpi Gakkai zasshi, 1974, Feb-20, Volume: 50, Issue:2

    Topics: Adult; Aldosterone; Corticosterone; Endocrine System Diseases; Female; Humans; Hypertension; Male; M

1974
[Proceedings: Hypertension--correlation between chronological changes of plasma renin activity and aldosterone levels in spontaneous hypertension in rats].
    Nihon Naibunpi Gakkai zasshi, 1974, Feb-20, Volume: 50, Issue:2

    Topics: Aldosterone; Animals; Hypertension; Rats; Renin

1974
[Proceedings: Quantification of aldosterone secretion in various types of hypertension (by radioimmunoassay)].
    Nihon Naibunpi Gakkai zasshi, 1974, Feb-20, Volume: 50, Issue:2

    Topics: Aldosterone; Humans; Hypertension; Radioimmunoassay

1974
[Proceedings: Plasma renin activity and aldosterone values in furosemide loading in various diseases].
    Nihon Naibunpi Gakkai zasshi, 1974, Feb-20, Volume: 50, Issue:2

    Topics: Aldosterone; Edema; Furosemide; Humans; Hypertension; Renin

1974
Management of potassium problems during long-term diuretic therapy.
    JAMA, 1974, Nov-04, Volume: 230, Issue:5

    Topics: Aldosterone; Diet; Diuretics; Extracellular Space; Homeostasis; Humans; Hydrogen-Ion Concentration;

1974
The effect of saline infusion and postural changes on plasma aldosterone in hypertension.
    Folia endocrinologica, 1974, Volume: 27, Issue:6pt2

    Topics: Adrenal Cortex; Adrenal Glands; Aldosterone; Diagnosis, Differential; Humans; Hypertension; Hyperten

1974
Antihypertensive effect of spironolactone in essential, renal and mineralocorticoid hypertension.
    Clinical science and molecular medicine. Supplement, 1973, Volume: 45 Suppl 1

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Di

1973
Renin suppression in hypertension in relation to body fluid volumes, patterns of sodium excretion and renal haemodynamics.
    Clinical science and molecular medicine. Supplement, 1973, Volume: 45 Suppl 1

    Topics: Adult; Age Factors; Aldosterone; Body Fluids; Female; Glomerular Filtration Rate; Hemodynamics; Huma

1973
Selective hypoaldosteronism: a case report and review of literature.
    The Medical annals of the District of Columbia, 1974, Volume: 43, Issue:12

    Topics: Adrenal Insufficiency; Adult; Aldosterone; Diabetes Complications; Heart Diseases; Humans; Hyperkale

1974
[Electrolytes and arterial hypertension].
    Acta cardiologica, 1973

    Topics: Aldosterone; Animals; Desoxycorticosterone; Drug Combinations; Electrolytes; Humans; Hypertension; P

1973
Possible role of 18-hydroxy-deoxycorticosterone in hypertension.
    Nature, 1972, Jun-09, Volume: 237, Issue:5354

    Topics: Aldosterone; Analysis of Variance; Animals; Corticosterone; Desoxycorticosterone; Diet; Female; Gene

1972
[Is essential hypertension still a disease entity? Definition of hyporeninemic hypertension].
    Der Internist, 1974, Volume: 15, Issue:3

    Topics: Aldosterone; Amiloride; Chlorthalidone; Diagnosis, Differential; Drug Combinations; Humans; Hydrochl

1974
[Secretion, distribution, and metabolism of aldosterone in various types of hypertension].
    Klinische Wochenschrift, 1972, Nov-15, Volume: 50, Issue:22

    Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Rena

1972
[Quadriplegia, severe hypokalemic alkalosis, tetany, arterial hypertension in relation to excessive licorice extract consumption in a chronic alcoholic].
    Lyon medical, 1972, Sep-10, Volume: 228, Issue:13

    Topics: Alcoholism; Aldosterone; Alkalosis; Chronic Disease; Diabetes Complications; Electrocardiography; Gl

1972
Adrenal adenoma and hypertension.
    Annals of internal medicine, 1972, Volume: 76, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hypertension

1972
Experience with the use of an aldosterone antagonist in selected hypertensive patients.
    Angiology, 1972, Volume: 23, Issue:10

    Topics: Adult; Aldosterone; Carbon Dioxide; Creatinine; Female; Humans; Hypertension; Kidney Function Tests;

1972
[Treatment of essential arterial hypertension with spironolactone: its value in the detection of primary hyperaldosteronism and prediction of its efficacy].
    Journal d'urologie et de nephrologie, 1972, Volume: 78, Issue:12

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Age Factors; Aldosterone; Diet Therapy; Humans; Hyperald

1972
[Pathogenesis of hypertension in primary aldosteronism].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1972, Volume: 78

    Topics: Aldosterone; Capillary Resistance; Humans; Hyperaldosteronism; Hypertension; Potassium

1972
[Radioimmunoassay of steroid hormones].
    Rinsho byori. The Japanese journal of clinical pathology, 1972, Volume: 20, Issue:6

    Topics: Addison Disease; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Radioimmunoass

1972
Studies on essential hypertension with suppressed plasma renin activity: sodium excretion pattern on salt restriction and effects of spironolactone on blood pressure and plasma renin activity.
    Japanese circulation journal, 1972, Volume: 36, Issue:12

    Topics: Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hyperaldost

1972
The diagnostic and therapeutic value of spironolactone in patients with systemic hypertension.
    Nephron, 1973, Volume: 9, Issue:3

    Topics: Acid-Base Equilibrium; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Press

1973
Essential hypertension--why idiopathic?
    The American journal of medicine, 1973, Volume: 54, Issue:1

    Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Cardiac Outpu

1973
Anomalous postural response of plasma aldosterone concentration in patients with aldosterone-producing adrenal adenoma.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 36, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism;

1973
A dissociated effect of amino-glutethimide on the mineralocorticoid secretion in man.
    Metabolism: clinical and experimental, 1973, Volume: 22, Issue:2

    Topics: Adult; Aldosterone; Aminoglutethimide; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Dexame

1973
Renin-secreting juxtaglomerular-cell adenoma. Preoperative clinical and angiographic diagnosis.
    Radiology, 1973, Volume: 106, Issue:3

    Topics: Adenoma; Adolescent; Aldosterone; Angiography; Humans; Hypertension; Kidney Neoplasms; Male; Radiogr

1973
New techniques in the diagnosis and treatment of hypertension.
    The Journal of the Indiana State Medical Association, 1973, Volume: 66, Issue:2

    Topics: Aldosterone; Hypertension; Pheochromocytoma; Thyroid Neoplasms

1973
Evaluation of a simplified technic for the measurement of aldosterone in human urine.
    American journal of clinical pathology, 1973, Volume: 59, Issue:1

    Topics: Aldosterone; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Female; Humans; Hydro

1973
Primary excess and deficiency or renin.
    British medical journal, 1973, Mar-17, Volume: 1, Issue:5854

    Topics: Adolescent; Adult; Aged; Aldosterone; Child; Endocrine System Diseases; Hemangiopericytoma; Humans;

1973
[Relationship between sweat, sodium and potassium excretion and the renin-angiotensin-aldosterone system in hypertension].
    Schweizerische medizinische Wochenschrift, 1973, Mar-24, Volume: 103, Issue:12

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Child

1973
Volume-dependent essential and steroid hypertension.
    The American journal of cardiology, 1973, Volume: 31, Issue:5

    Topics: Adult; Aged; Aldosterone; Diet, Sodium-Restricted; Female; Follow-Up Studies; Humans; Hydrochlorothi

1973
Plasma and extracellular fluid volumes in hypertension.
    Circulation research, 1973, May-05, Volume: 32

    Topics: Aldosterone; Blood Pressure; Diuretics; Extracellular Space; Humans; Hyperaldosteronism; Hypertensio

1973
Renin subgroups in essential hypertension. Further analysis of their pathophysiological and epidemiological characteristics.
    Circulation research, 1973, May-05, Volume: 32

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aldosterone; Bicarbonates; Blood Urea Nitrogen; Diet

1973
Experience with primary aldosteronism.
    The Journal of urology, 1973, Volume: 110, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Female; Follow-Up Studies; Huma

1973
[Studies on the autonomy of aldosterone secretion in primary hyperaldosteronism. Diagnosis and differential diagnosis of "Conn's syndrome"].
    Klinische Wochenschrift, 1973, Apr-15, Volume: 51, Issue:8

    Topics: Adrenal Glands; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; M

1973
Role of renin and aldosterone in hypertension due to a renin-secreting tumor.
    The American journal of medicine, 1973, Volume: 55, Issue:1

    Topics: Adrenalectomy; Adult; Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Kidney; Kidney Neo

1973
Periodic hypokalaemic paralysis, adrenal adenoma, and normal colonic transport of sodium and potassium.
    Gut, 1973, Volume: 14, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Colon; Corticosterone; Desoxycorticosterone; Feces; F

1973
The pressor effects of application of digoxin to the carotid sinus.
    East African medical journal, 1973, Volume: 50, Issue:1

    Topics: Aldosterone; Animals; Blood Pressure; Carotid Sinus; Digoxin; Hypertension; Male; Rabbits

1973
[Significance of hyperaldosteronism in the pathogenesis of arterial hypertension in pheochromocytoma].
    Kardiologiia, 1973, Volume: 13, Issue:5

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aldosterone; Biopsy; Catecholamines; Chromatography, Thi

1973
Diagnostic considerations in secondary hypertension.
    Texas medicine, 1973, Volume: 69, Issue:7

    Topics: Aldosterone; Aortic Coarctation; Contraceptives, Oral; Cushing Syndrome; Diagnosis, Differential; Hu

1973
Primary amenorrhoea with hypertension due to 17-hydroxylase deficiency. Therapy with dexamethasone and ethinyloestradiol.
    Acta medica Scandinavica, 1973, Volume: 193, Issue:6

    Topics: Adult; Aldosterone; Amenorrhea; Dexamethasone; Diet, Sodium-Restricted; Estrogens; Ethinyl Estradiol

1973
Adrenocortical carcinoma with an isolated mineralocorticoid excess and recurrency fourteen years after removal of the tumor.
    The Tohoku journal of experimental medicine, 1973, Volume: 109, Issue:4

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Humans; Hydrocortisone; Hypertension; M

1973
A calcified aldosterone-producing tumor in a hypertensive, normokalemic, prepubertal girl.
    The Journal of pediatrics, 1973, Volume: 83, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Calcinosis; Child; Child Behavior Disorders; Desoxyco

1973
Effect of PGA1 on renin and aldosterone in man.
    Prostaglandins, 1973, Volume: 3, Issue:5

    Topics: 17-Hydroxycorticosteroids; Adult; Aldosterone; Blood Pressure; Body Weight; Depression, Chemical; Di

1973
Antihypertensive action of propranolol. Specific antirenin responses in high and normal renin forms of essential, renal, renovascular and malignant hypertension.
    The American journal of cardiology, 1973, Sep-20, Volume: 32, Issue:4

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Child; Female; Humans; Hypertensi

1973
Volume factor in low and normal renin essential hypertension. Treatment with either spironolactone or chlorthalidone.
    The American journal of cardiology, 1973, Sep-20, Volume: 32, Issue:4

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Chlorthalidone; Creatinine; Female; H

1973
Plasma aldosterone-renin interrelationships in various forms of essential hypertension. Studies using a rapid assay of plasma aldosterone.
    The American journal of cardiology, 1973, Sep-20, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Child; Diet; Female; Humans; Hypertension; Male; Methods; Middle Age

1973
[Treatment of essential arterial hypertension with spironolactone: its value for the screening of primary hyperaldosteronism and prediction of its efficacy].
    Therapeutique (La Semaine des hopitaux), 1973, Volume: 49, Issue:2

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Probability; Spironolactone

1973
[The role of anti-aldosterones in the treatment of arterial hypertension].
    La Revue du praticien, 1973, Feb-11, Volume: 23, Issue:9

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Potas

1973
[Diagnosis of adrenal gland neoplasms causing primary aldosteronism by determination of plasma aldosterone in adrenal- or renal-vein blood].
    Nihon Naibunpi Gakkai zasshi, 1973, Jun-20, Volume: 49, Issue:6

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Child; Female; Humans; Hype

1973
Hyporeninemic hypertension.
    JAMA, 1973, Jan-08, Volume: 223, Issue:2

    Topics: Aldosterone; Diet, Sodium-Restricted; Humans; Hypertension; Renin

1973
The physiology of renin secretion in essential hypertension. Estimation of renin secretion rate and renal plasma flow from peripheral and renal vein renin levels.
    The American journal of medicine, 1973, Volume: 55, Issue:3

    Topics: Aldosterone; Arteries; Blood Pressure; Humans; Hypertension; Kidney; Radiography; Regional Blood Flo

1973
Editorial: Some thoughts on sodium homoeostasis.
    The Medical journal of Australia, 1973, Dec-22, Volume: 2, Issue:25

    Topics: Aldosterone; Blood Pressure; Glomerular Filtration Rate; Homeostasis; Humans; Hypertension; Kidney T

1973
[Radioimmunoassay for urinary aldosterone. Aldosterone excretion in essential hypertensives (author's transl)].
    Klinische Wochenschrift, 1973, Dec-01, Volume: 51, Issue:23

    Topics: Aldosterone; Buffers; Chromatography, Paper; Chromatography, Thin Layer; Cross Reactions; Humans; Hy

1973
A comparison of double-isotope derivative and radioimmunological estimation of plasma aldosterone concentration in man.
    Clinical science and molecular medicine, 1973, Volume: 45, Issue:3

    Topics: Aldosterone; Carbon Radioisotopes; Female; Humans; Hypertension; Isotope Labeling; Methods; Pregnanc

1973
[Humoral disorders in hypertensive disease].
    Vrachebnoe delo, 1973, Volume: 11

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Aldosterone; Catechol

1973
[Role of corticosteroids in the pathogenesis of primary arterial hypertension in adolescents].
    Vestnik Akademii meditsinskikh nauk SSSR, 1973, Volume: 28, Issue:12

    Topics: Adolescent; Adrenal Cortex Hormones; Age Factors; Aldosterone; Child; Chromatography, Thin Layer; Co

1973
[The secondary disease in internal medicine (antibacterial chemotherapy)].
    International journal of clinical pharmacology, therapy and toxicology, 1973, Volume: 8, Issue:4

    Topics: Aldosterone; Anti-Infective Agents; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Huma

1973
Ultrastructural features of corticomedullary cells in a human adrenocortical adenoma and in rat adrenal cortex.
    Anatomischer Anzeiger, 1973, Volume: 134, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Animals; Catecholamines;

1973
[Plasma aldosterone and plasma renin activity during hemodialysis].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1973, Volume: 79

    Topics: Aldosterone; Humans; Hypertension; Potassium; Renal Dialysis; Renin; Time Factors

1973
Radioimmunoassay of aldosterone in plasma and urine: validation of a novel separation technique and a rapid urine assay.
    Clinical science and molecular medicine, 1973, Volume: 45, Issue:5

    Topics: Aldosterone; Animals; Chromatography, Paper; Cross Reactions; Female; Furosemide; Humans; Hydrocorti

1973
Actual incidence of secondary hypertension.
    Japanese circulation journal, 1973, Volume: 37, Issue:9

    Topics: Adult; Aldosterone; Biopsy; Blood Pressure; Catecholamines; Cushing Syndrome; Diagnosis, Differentia

1973
On the mechanism of suppressed plasma-renin activity during beta-adrenergic blockade with propranolol.
    The Journal of laboratory and clinical medicine, 1974, Volume: 83, Issue:1

    Topics: Adult; Aldosterone; Diet, Sodium-Restricted; Diuretics; Female; Humans; Hypertension; Injections, In

1974
Plasma steroids in rats with experimental ectopic pituitary tumor and arterial hypertension.
    Endocrinology, 1974, Volume: 94, Issue:2

    Topics: Adrenal Glands; Aldosterone; Animals; Binding, Competitive; Corticosterone; Desoxycorticosterone; Hy

1974
[Aldosterone excretion in patients with essential hypertension after variable sodium loading (author's transl)].
    Klinische Wochenschrift, 1974, Jan-15, Volume: 52, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Radioimm

1974
Mineralocorticoid receptors and 18-hydroxydeoxycorticosterone binding in the kidney of the spontaneously hypertensive rat.
    Endocrinology, 1974, Volume: 94, Issue:4

    Topics: Aldosterone; Animals; Binding, Competitive; Corticosterone; Cytoplasm; Dexamethasone; Female; Hypert

1974
[Excretion of corticosteroids in the urine in adolescents with primary arterial hypertension].
    Pediatriia, 1974, Volume: 53, Issue:4

    Topics: Adrenal Cortex Hormones; Aldosterone; Corticosterone; Cortisone; Humans; Hypertension; Tetrahydrocor

1974
[Aldosterone-Aldosteronism].
    Zeitschrift fur Allgemeinmedizin, 1974, Apr-30, Volume: 50, Issue:12

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Male; Potassium; Sodium

1974
Normal renin secretion in hypertensive patients with primarily unilateral chronic hydronephrosis.
    The Journal of urology, 1974, Volume: 112, Issue:2

    Topics: Adult; Aged; Aldosterone; Chronic Disease; Female; Humans; Hydronephrosis; Hypertension; Hypertensio

1974
[Hormonal studies in clinical aspects of internal diseases].
    Sovetskaia meditsina, 1974, Volume: 37, Issue:6

    Topics: Adrenal Glands; Aldosterone; Epinephrine; Humans; Hyperaldosteronism; Hypertension; Norepinephrine;

1974
[Endocrine hypertension syndromes of adrenal pathogenesis. II. Syndromes due to hyperaldosteronism and hypercortisolism].
    Minerva medica, 1974, Jun-09, Volume: 65, Issue:44

    Topics: Adrenocortical Hyperfunction; Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hydrocort

1974
Renin, aldosterone, body fluid volumes, and the baroreceptor reflex in the development and reversal of Goldblatt hypertension in conscious dogs.
    Circulation research, 1974, Volume: 34, Issue:4

    Topics: Adrenal Glands; Aldosterone; Animals; Aorta, Thoracic; Blood Pressure; Body Fluids; Denervation; Dog

1974
[Anephric man].
    Journal d'urologie et de nephrologie, 1968, Volume: 74, Issue:12

    Topics: Aldosterone; Animals; Arteries; Blood Glucose; Body Weight; Diet Therapy; Dogs; Erythropoiesis; Hema

1968
[Aldosteronism. Evolution of the problem from 1955 to 1969].
    Srpski arhiv za celokupno lekarstvo, 1969, Volume: 97, Issue:9

    Topics: Adult; Aldosterone; Diagnosis, Differential; Female; History, 20th Century; Humans; Hyperaldosteroni

1969
Quadric analysis in the preoperative distinction between patients with and without adrenocortical tumors in hypertension with aldosterone excess and low plasma renin.
    American heart journal, 1971, Volume: 82, Issue:5

    Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Aldosterone; Bicarbonates; Blood Pr

1971
The effects of sodium loading and deprivation on plasma renin and plasma and urinary aldosterone in hypertension.
    Clinical science, 1972, Volume: 42, Issue:1

    Topics: Aldosterone; Corticosterone; Diet, Sodium-Restricted; Humans; Hydrocortisone; Hypertension; Potassiu

1972
Hyporeninemic hypertension.
    The American journal of medicine, 1972, Volume: 52, Issue:4

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Blood Urea Nitrogen; Catecholamines; Diet, Sod

1972
The 'hypertensive' evaluation.
    American family physician, 1972, Volume: 5, Issue:2

    Topics: Abdomen; Aldosterone; Auscultation; Blood Cell Count; Blood Pressure; Blood Urea Nitrogen; Catechola

1972
Primary aldosteronism. Review of diagnostic tests and 15 cases.
    The Journal of the Kansas Medical Society, 1972, Volume: 73, Issue:5

    Topics: Academic Dissertations as Topic; Adult; Aged; Aldosterone; Diagnosis, Differential; Electrolytes; Ev

1972
A new male pseudo-hermaphroditism associated with hypertension due to a block of 17 -hydroxylation.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 35, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aldosterone; Corticosterone; Desoxycorticosterone

1972
New evidences of disturbances of mineralocorticoid activity in benign, uncomplicated essential hypertension.
    Transactions of the American Clinical and Climatological Association, 1972, Volume: 83

    Topics: 17-Hydroxycorticosteroids; Adult; Aldosterone; Female; Humans; Hypertension; Male; Metabolic Clearan

1972
[Mineralocorticoid reaction of hypertensive patients to spirolactone].
    Vnitrni lekarstvi, 1972, Volume: 18, Issue:6

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Metabolic Clearance Rate; Sodium; Spironolactone

1972
[Sympathico-reno-adrenal relationship in some kinds of hypertensions].
    Sbornik lekarsky, 1972, Volume: 74, Issue:7

    Topics: Adrenal Glands; Aldosterone; Catecholamines; Humans; Hypertension; Kidney; Renin; Sympathetic Nervou

1972
Hypertension with primary and secondary hyperaldosteronism.
    Postgraduate medicine, 1972, Volume: 52, Issue:3

    Topics: Adenoma; Aldosterone; Blood Pressure; Contraceptives, Oral; Diuretics; Humans; Hyperaldosteronism; H

1972
Renin, aldosterone, sodium and hypertension.
    The American journal of medicine, 1972, Volume: 52, Issue:2

    Topics: Adrenal Glands; Adult; Age Factors; Aged; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Kid

1972
Electrolyte changes in patients with subarachnoid haemorrhage.
    Clinical science, 1972, Volume: 42, Issue:2

    Topics: Acute Disease; Aldosterone; Alkalosis, Respiratory; Aminohippuric Acids; Carbon Dioxide; Extracellul

1972
Studies on the renin-angiotensin-aldosterone system: studies on histological changes in adrenal and renal tissue; a follow-up study of postoperative blood pressure in primary and idiopathic aldosteronism.
    Japanese circulation journal, 1972, Volume: 36, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Biopsy; Blood P

1972
Steroid secretion by the enucleated rat adrenal: measurements during salt retention and the development of hypertension.
    Endocrinology, 1972, Volume: 91, Issue:5

    Topics: Adrenal Glands; Adrenal Medulla; Aldosterone; Animals; Blood Pressure; Chromatography, Thin Layer; C

1972
[SP 54 therapy in hypertension. The effect of SP 54 on blood pressure, renin and aldosterone as well as electrolyte balance in patients with hypertension].
    Fortschritte der Medizin, 1972, Jul-20, Volume: 90, Issue:20

    Topics: Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Midd

1972
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-1972.
    The New England journal of medicine, 1972, Sep-28, Volume: 287, Issue:13

    Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Diagnosis, Di

1972
Propranolol inhibition of renin secretion. A specific approach to diagnosis and treatment of renin-dependent hypertensive diseases.
    The New England journal of medicine, 1972, Dec-14, Volume: 287, Issue:24

    Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Depression, Chemical; Humans; Hypertens

1972
The pattern of plasma renin activity and aldosterone secretion in normal and hypertensive subjects before and after saline infusions.
    The American journal of cardiology, 1971, Volume: 27, Issue:6

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Blood Pressure; Di

1971
The pattern of electrolyte excretion in normal and hypertensive subjects before and after saline infusions. A simple electrolyte formula for the diagnosis of primary aldosteronism.
    The American journal of cardiology, 1971, Volume: 27, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Body Weight; Diet; Female; Hum

1971
The diagnostic value of salt depletion and salt loading in screening for secondary hypertension.
    The American journal of cardiology, 1971, Volume: 27, Issue:6

    Topics: Adrenal Glands; Aldosterone; Hyperaldosteronism; Hypertension; Hypertonic Solutions; Kidney; Natriur

1971
Saline suppression of plasma aldosterone in hypertension.
    Archives of internal medicine, 1971, Volume: 128, Issue:3

    Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Infusions, Paren

1971
Renin and aldosterone in essential hypertension.
    Clinical science, 1971, Volume: 41, Issue:4

    Topics: Aldosterone; Catecholamines; Diet, Sodium-Restricted; Feces; Humans; Hyperaldosteronism; Hypertensio

1971
Sodium and hypertension.
    Japanese circulation journal, 1971, Volume: 35, Issue:5

    Topics: Aldosterone; Amidines; Aorta; Depression, Chemical; Diuretics; Epinephrine; Heart Atria; Heart Ventr

1971
Adrenal arteriography and venography in primary aldosteronism.
    Radiology, 1971, Volume: 101, Issue:1

    Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Angiog

1971
A decreased metabolic clearance rate of aldosterone in benign essential hypertension.
    The Journal of clinical investigation, 1971, Volume: 50, Issue:10

    Topics: Adaptation, Physiological; Adolescent; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hyper

1971
Testosterone-induced 18-hydroxylase block: a new form of steroid hypertension in man.
    The Journal of laboratory and clinical medicine, 1971, Volume: 78, Issue:5

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Corticosterone; Female; Humans; Hydroxylation; Hyperten

1971
Low renin hypertension: a state of inappropriate secretion of aldosterone.
    The Journal of laboratory and clinical medicine, 1971, Volume: 78, Issue:5

    Topics: Aldosterone; Humans; Hypertension; Renin

1971
Evaluation of renal vascular hypertension and primary hyperaldosteronism.
    California medicine, 1971, Volume: 115, Issue:6

    Topics: Aldosterone; Angiography; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Hyperte

1971
Effects of hydrochlorothiazide, furosemide and ethacrynic acid on pinealectomy-induced hypertension in rats.
    Annales medicinae experimentalis et biologiae Fenniae, 1971, Volume: 49, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Ethacrynic Acid; Furosemide; Hydrochlorothiazide; Hypertension

1971
Hypertension and low plasma renin activity: presumptive evidence for mineralocorticoid excess.
    Annals of internal medicine, 1971, Volume: 75, Issue:6

    Topics: Adrenal Glands; Aldosterone; Blood Pressure; Body Weight; Carbon Dioxide; Chlorides; Female; Humans;

1971
[Pharmacological and clinical bases for the use of diuretics in pregnancy].
    Minerva ginecologica, 1971, Dec-15, Volume: 23, Issue:23

    Topics: Adult; Aldosterone; Blood Pressure; Carbohydrate Metabolism; Diuretics; Edema; Female; Fetus; Hormon

1971
Evaluation of select criteria for the diagnosis of primary aldosteronism in normokalemic hypertension.
    The American journal of the medical sciences, 1971, Volume: 262, Issue:5

    Topics: Adult; Aldosterone; Desoxycorticosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Mi

1971
Effects of an aldosterone antagonist, spironolactone, on pinealectomized rats.
    Pharmacology, 1971, Volume: 6, Issue:5

    Topics: Adrenal Glands; Aldosterone; Animals; Arteries; Blood Pressure; Epinephrine; Hypertension; Male; Min

1971
Sodium, aldosterone and hypertension.
    East African medical journal, 1971, Volume: 48, Issue:9

    Topics: Aldosterone; Blood Pressure; Humans; Hypertension; Kidney; Kidney Diseases; Sodium

1971
[Primary aldosteronism from the viewpoint of own observations].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1971, Oct-01, Volume: 26, Issue:19

    Topics: 17-Ketosteroids; Adrenal Glands; Aldosterone; Germany, East; Humans; Hyperaldosteronism; Hypertensio

1971
Fecal and salivary electrolytes in the diagnosis of primary aldosteronism.
    Canadian Medical Association journal, 1971, Dec-18, Volume: 105, Issue:12

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Feces; Female; Humans; Hyperaldosteronism; Hyp

1971
[Clinical studies on the relation between aldosterone and various hypertensive and renal diseases. 1. Studies on the secretion and metabolism of aldosterone in various hypertensive and renal diseases].
    Naika hokan. Japanese archives of internal medicine, 1971, Volume: 18, Issue:8

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Kidney Diseases; Time Factors; Tritium

1971
Structure-function studies of the regenerating adrenal.
    Transactions of the New York Academy of Sciences, 1969, Volume: 31, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Corticosterone; Culture Techniques; Desoxycorti

1969
Episodic hypertension associated with positive renin assays after renal transplantation.
    The New England journal of medicine, 1966, Mar-10, Volume: 274, Issue:10

    Topics: Adult; Aldosterone; Humans; Hypertension; Ischemia; Kidney Transplantation; Male; Renin; Transplanta

1966
Plasma renin activity and aldosterone secretion in a pregnant woman with primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Biological Assay; Female; Humans; Hyper

1967
Renal hypertension and renin hypertension in intact and in adrenalectomized rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 132, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Constriction; Corticosterone; Dexamethasone; Hy

1969
In vitro metabolism of progesterone by the adrenals of spontaneously hypertensive rats.
    Experientia, 1969, Aug-15, Volume: 25, Issue:8

    Topics: Adrenal Glands; Aldosterone; Animals; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Female;

1969
Effects of sodium loading, sodium depletion and posture on plasma aldosterone concentration and renin activity in hypertensive patients.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:10

    Topics: Adolescent; Adult; Aged; Aldosterone; Child; Female; Humans; Hydrocortisone; Hypertension; Male; Mid

1969
[Primary aldosteronism without association of hypokalemia].
    Naika. Internal medicine, 1969, Volume: 24, Issue:4

    Topics: 17-Hydroxycorticosteroids; Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hyperkalemia; Hy

1969
Hypertension induced by oral contraceptives containing estrogen and gestagen. Effects on plasma renin activity and aldosterone excretion.
    Annals of internal medicine, 1969, Volume: 71, Issue:5

    Topics: Adult; Aldosterone; Benzothiadiazines; Blood Pressure; Contraceptives, Oral; Female; Humans; Hyperte

1969
Hypertension and hyperaldosteronism with low plasma renin concentration: analysis of a series of eighty-two patients.
    Proceedings of the Royal Society of Medicine, 1969, Dec-12, Volume: 62, Issue:12

    Topics: Adrenal Glands; Aldosterone; Body Weight; Humans; Hyperaldosteronism; Hypertension; Plasma Volume; P

1969
[Saluretics and hypertension].
    La Clinica terapeutica, 1969, Volume: 51, Issue:1

    Topics: Aldosterone; Catecholamines; Diuretics; Humans; Hypertension; Potassium; Sodium

1969
Suppressed plasma renin activity in in hypertensive patients--its evaluation for the diagnosis of primary aldosteronism.
    The Tohoku journal of experimental medicine, 1969, Volume: 99, Issue:4

    Topics: Aldosterone; Cushing Syndrome; Diet, Sodium-Restricted; Glomerulonephritis; Humans; Hydrochlorothiaz

1969
[Measurement of aldosterone in peripheral blood and urine--analysis of the method and evaluation of estimated values in normal subjects and aldosteronism].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1969, Oct-10, Volume: 58, Issue:10

    Topics: Adult; Aldosterone; Carbon Isotopes; Child; Chromatography, Paper; Female; Humans; Hyperaldosteronis

1969
[Aldosteronism].
    Chirurgia e patologia sperimentale, 1969, Volume: 17, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin

1969
[Aldosterone secretion in arterial hypertension].
    Tip Fakultesi mecmuasi, 1969, Volume: 32, Issue:4

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Middle Aged

1969
[Morphological signs of hyperactivity of the renin-aldosterone system in experimental cadmium-induced hypertension].
    La Medicina del lavoro, 1969, Volume: 60, Issue:4

    Topics: Aldosterone; Animals; Cadmium; Hypertension; Juxtaglomerular Apparatus; Rats; Renin

1969
Pseudopheochromocytoma--adrenomedullary response to venography.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:1

    Topics: Adrenal Medulla; Aldosterone; Diatrizoate; Epinephrine; Humans; Hydrocortisone; Hypertension; Norepi

1970
A physiologic approach to curable hypertension.
    The Surgical clinics of North America, 1970, Volume: 50, Issue:1

    Topics: Adrenal Gland Neoplasms; Aldosterone; Cardiovascular Diseases; Catecholamines; Diagnosis, Differenti

1970
Studies on catecholamines, renin and aldosterone following Catapresan (2-(2,6-dichlor-phenylamine)-2-imidazoline hydrochloride) in hypertensive patients.
    European journal of pharmacology, 1970, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Catecholamines; Depre

1970
Renin, aldosterone, and hypertension. The hepatic metabolism of renin and aldosterone. A review with new observations on the hepatic clearance of renin.
    Circulation research, 1970, Volume: 27, Issue:1 Suppl 1

    Topics: Aldosterone; Animals; Blood; Disease Models, Animal; Dogs; Heart Failure; Hemorrhage; Hepatic Veins;

1970
The intercurrent hypertension of primary aldosteronism.
    Circulation research, 1970, Volume: 27, Issue:1 Suppl 1

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Body Weight; Chronic Disease; Desoxyc

1970
The role of renin in the exaggerated natriuresis of hypertension.
    Circulation, 1970, Volume: 42, Issue:2

    Topics: Adult; Aldosterone; Ethacrynic Acid; Female; Furosemide; Glomerular Filtration Rate; Humans; Hyperal

1970
[Orthostatic reaction disorders in the etiopathogenesis of various pathologic conditions].
    Casopis lekaru ceskych, 1970, Mar-06, Volume: 109, Issue:11

    Topics: Addison Disease; Aldosterone; Edema; Hemodynamics; Humans; Hypertension; Hypertension, Renal; Hypote

1970
[Research on arterial hypertension. Significance of aldosterone, catecholamines, amino acids and some electrolytes].
    Medicina interna, 1970, Volume: 22, Issue:3

    Topics: Aldosterone; Amino Acids; Catecholamines; Electrolytes; Humans; Hypertension; Hypertension, Malignan

1970
Oral contraceptives and hypertension.
    British medical journal, 1970, Aug-01, Volume: 3, Issue:5717

    Topics: Aldosterone; Animals; Contraceptives, Oral; Hypertension; Progesterone; Rabbits; Sodium Chloride

1970
[Renin-angiotensin-aldosterone system: effect of the hypertensive agents on plasma renin activity and clinical application, especially in screening of primary aldosteronism and other simialr diseases].
    Japanese circulation journal, 1970, Volume: 34, Issue:3

    Topics: Adolescent; Adult; Aldosterone; Animals; Blood Pressure; Denervation; Diazoxide; Dogs; Female; Glome

1970
The effects of progesterone on the responses of the cardiovascular system to intravenous infusions of aldosterone.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1970, Volume: 77, Issue:10

    Topics: Aldosterone; Animals; Blood Pressure; Contraceptives, Oral; Drug Synergism; Female; Femoral Artery;

1970
[Functional hyperaldosteronism].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1970, Dec-01, Volume: 90, Issue:23

    Topics: Aldosterone; Dexamethasone; Hyperaldosteronism; Hypertension; Hypokalemia; Renin

1970
A preliminary evaluation for primary aldosteronism.
    Archives of internal medicine, 1970, Volume: 126, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Desoxycorticosterone; Fludrocortisone

1970
Hypertension and severe hyperkalaemia associated with suppression of renin and aldosterone and completely reversed by dietary sodium restriction.
    Australasian annals of medicine, 1970, Volume: 19, Issue:4

    Topics: Aldosterone; Ammonia; Bicarbonates; Blood Urea Nitrogen; Child; Chlorides; Creatinine; Diet, Sodium-

1970
Hypertension and adrenal cortex disease. A review of 100 autopsied cases.
    The Ohio State medical journal, 1970, Volume: 66, Issue:12

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Autopsy; Fem

1970
Plasma renin activity in human hypertension.
    Circulation research, 1970, Volume: 27

    Topics: Adult; Aldosterone; Blood Pressure; Contraceptives, Oral; Female; Humans; Hypertension; Kidney Failu

1970
Sodium homeostasis, salt appetite, and hypertension.
    Circulation research, 1970, Volume: 27

    Topics: Aldosterone; Animals; Anxiety; Appetite; Bicarbonates; Diet; Diet, Sodium-Restricted; Female; Food A

1970
Sodium balance, plasma renin, and aldosterone in hypertension.
    Circulation research, 1970, Volume: 27

    Topics: Aldosterone; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; R

1970
[Research on arterial hypertension. Significance of aldosterone, catecholamines, amino acids and some electrolytes in compensated and decompensated cardiac lesions].
    Medicina interna, 1970, Volume: 22, Issue:7

    Topics: Adult; Aged; Aldosterone; Amino Acids; Catecholamines; Coronary Disease; Electrolytes; Female; Heart

1970
Panel discussion: the incidence of aldosteronism and early detection in the population.
    American journal of clinical pathology, 1970, Volume: 54, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Immunoassay

1970
[Hypertension and tachycardia in acute intermittent porphyria].
    Klinische Wochenschrift, 1970, Jan-01, Volume: 48, Issue:1

    Topics: Adult; Aldosterone; Amino Acids; Anemia; Blood Pressure; Catecholamines; Depression, Chemical; Elect

1970
Hypertension, adrenal abnormalities, and alterations in plasma renin activity.
    Annals of internal medicine, 1970, Volume: 73, Issue:6

    Topics: Adenoma; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldoste

1970
Plasma renin activity and aldosterone secretion rate in hypertension. The distinction between primary and secondary hyperaldosteronism.
    Acta medica Scandinavica, 1970, Volume: 187, Issue:5

    Topics: Adolescent; Adrenalectomy; Adult; Aged; Aldosterone; Carbon Isotopes; Creatinine; Female; Humans; Hy

1970
[Diagnosis of arterial hypertension].
    Munchener medizinische Wochenschrift (1950), 1970, Oct-09, Volume: 112, Issue:41

    Topics: 17-Hydroxycorticosteroids; Aldosterone; Angiography; Aortic Valve Stenosis; Arteries; Catecholamines

1970
Sodium space and electrolyte excretion during the menstrual cycle.
    American journal of obstetrics and gynecology, 1971, Jan-01, Volume: 109, Issue:1

    Topics: Aldosterone; Basal Metabolism; Body Temperature; Body Weight; Creatinine; Female; Humans; Hypertensi

1971
Dietary salt intake in hypertensive patients with normal and low plasma renin activity.
    The American journal of the medical sciences, 1971, Volume: 261, Issue:2

    Topics: Adult; Aldosterone; Creatinine; Diet; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Re

1971
Hypertension in apparently normal children.
    The Journal of pediatrics, 1971, Volume: 78, Issue:4

    Topics: Adolescent; Age Factors; Aldosterone; Blood Pressure; Child; Child, Preschool; Female; Humans; Hyper

1971
[Clinical evaluation of a new method for the determination of urinary aldosterone].
    Minerva medica, 1971, Jul-28, Volume: 62, Issue:59

    Topics: Aldosterone; Chromatography, Thin Layer; Edema; Female; Heart Diseases; Humans; Hyperaldosteronism;

1971
Primary aldosteronism associated with acute intermittent porphyria. Report of a case.
    The New England journal of medicine, 1971, Sep-09, Volume: 285, Issue:11

    Topics: Acyltransferases; Adult; Aldosterone; Catheterization; Enzyme Induction; Feces; Female; Humans; Hype

1971
[Essential hypertension--an endocrine form of hypertension].
    Hippokrates, 1971, Volume: 42, Issue:2

    Topics: Aldosterone; Humans; Hypertension; Renin

1971
Saline suppression of plasma aldosterone and plasma renin activity in hypertension.
    Arizona medicine, 1971, Volume: 28, Issue:4

    Topics: Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension; Male; Postur

1971
[Endocrinologic and circulatory findings in a case of primary aldosteronism].
    Deutsche medizinische Wochenschrift (1946), 1971, May-28, Volume: 96, Issue:22

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Female; Hemodynamics; Humans; Hyperaldosteronism; Hyp

1971
A dynamic study of plasma renin activity and aldosterone concentration in normal and hypertensive subjects.
    Metabolism: clinical and experimental, 1971, Volume: 20, Issue:5

    Topics: Adolescent; Adult; Aldosterone; Body Weight; Diuresis; Female; Furosemide; Humans; Hyperaldosteronis

1971
Low-renin essential hypertension--another form of childhood hypertension.
    The Journal of pediatrics, 1971, Volume: 78, Issue:5

    Topics: Aldosterone; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Hypertension; Infant; Infan

1971
[Intracellular electrolyte variations in experimental hypertension].
    Zeitschrift fur Kreislaufforschung, 1967, Volume: 56, Issue:7

    Topics: Aldosterone; Animals; Aorta; Desoxycorticosterone; Humans; Hyperparathyroidism; Hypertension; Male;

1967
[Present hypertension problems].
    Schweizerische medizinische Wochenschrift, 1967, Mar-18, Volume: 97, Issue:11

    Topics: Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Renin

1967
[Study of the juxtaglomerular apparatus in various forms of experimental hypertension].
    Kardiologiia, 1967, Volume: 7, Issue:9

    Topics: Aldosterone; Animals; Arteries; Blood Pressure; Constriction; Hyperplasia; Hypertension; Hypertensio

1967
[Primary aldosteronism].
    Annali italiani di chirurgia, 1967, Volume: 43, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi

1967
The role of aldosterone in hypernatremic dehydration in infants.
    Acta paediatrica Scandinavica, 1968, Volume: 57, Issue:1

    Topics: Aldosterone; Anuria; Dehydration; Gastroenteritis; Humans; Hypernatremia; Hypertension; Hypokalemia;

1968
Effects of renin on aldosterone secretion in the rat.
    Canadian journal of physiology and pharmacology, 1968, Volume: 46, Issue:1

    Topics: Aldosterone; Animals; Arteries; Blood Pressure; Female; Hypertension; Kidney; Myocardium; Nephrectom

1968
Plasma renin activity and aldosterone secretion in hypertensive patients during high and low sodium intake and administration of diuretic.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:3

    Topics: Adult; Aldosterone; Blood Pressure; Child; Chlorothiazide; Cushing Syndrome; Diet; Female; Humans; H

1968
Primary aldosteronism: review of 12 cases and present diagnostic criteria.
    Southern medical journal, 1968, Volume: 61, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi

1968
Primary aldosteronism: experience with current diagnostic criteria and surgical treatment in fourteen patients.
    Annals of surgery, 1968, Volume: 167, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Female; Humans; Hyperaldosteron

1968
Incidence of suppressed renin activity and of normokalemic primary aldosteronism in hypertensive Negro patients.
    Circulation, 1968, Volume: 37, Issue:6

    Topics: Adult; Aldosterone; Black People; Chlorothiazide; Diet, Sodium-Restricted; Female; Humans; Hyperaldo

1968
Plasma renin activity in congenital virilizing adrenal hyperplasia.
    Pediatrics, 1968, Volume: 41, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfun

1968
Unilateral adrenalectomy for aldosteronomas localized preoperatively by differential adrenal vein catheterization.
    Surgery, 1968, Volume: 64, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Angiography; Ao

1968
Hormonally maintained high blood pressure following adrenalectomy in rats with adrenal-regeneration hypertension and its possible significance in the etiology of that disorder.
    Canadian journal of physiology and pharmacology, 1968, Volume: 46, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Blood Pressure; Body Weight; Corticosterone; Fe

1968
Primary aldosteronism.
    The Practitioner, 1968, Volume: 200, Issue:198

    Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor An

1968
Metabolic and hormonal studies in a patient with primary aldosteronism, presenting with acute hypokalaemic paresis induced by chlorothiazide.
    Australasian annals of medicine, 1968, Volume: 17, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Chlorothiazide; Diagnosis, Diff

1968
[Excretion of aldosterone and the mineralocorticoid function of adrenal glands in diffuse glomerulonephritis].
    Klinicheskaia meditsina, 1968, Volume: 46, Issue:5

    Topics: Adolescent; Adrenal Glands; Adult; Aldosterone; Female; Glomerulonephritis; Humans; Hypertension; Ma

1968
Aldosterone secretion rate in the hypertensive form of congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:10

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Aldosterone; Cortisone; Diet; Disorders of Sex Deve

1968
Surgical treatment of adrenal disorders associated with increased hormone production.
    Acta chirurgica Academiae Scientiarum Hungaricae, 1968, Volume: 9, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adult;

1968
Aldosteronism in hypertension. The spironolactone response test.
    Annals of internal medicine, 1968, Volume: 69, Issue:4

    Topics: Adrenalectomy; Aldosterone; Blood Pressure; Body Weight; Diagnosis, Differential; Electrolytes; Huma

1968
Aldosterone secretion in hypertension.
    Annals of internal medicine, 1968, Volume: 69, Issue:4

    Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Antihyp

1968
Incidence of primary aldosteronism uncomplicated "essential" hypertension. A prospective study with elevated aldosterone secretion and suppressed plasma renin activity used as diagnostic criteria.
    JAMA, 1968, Aug-12, Volume: 205, Issue:7

    Topics: Adolescent; Adult; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hyperte

1968
Studies on cardiac output to blood volume, and renal circulation in chronic congestive heart failure.
    Japanese circulation journal, 1968, Volume: 32, Issue:3

    Topics: Adult; Aged; Aldosterone; Arteriosclerosis; Blood Pressure; Blood Volume; Cardiac Output; Chronic Di

1968
Metabolic studies on hypertensive patients with suppressed plasma renin activity not due to hyperaldosternosm.
    Circulation, 1968, Volume: 38, Issue:5

    Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Blood Volume; Body Weight; E

1968
[Secretion, plasma concentration, distribution, metabolism and excretion of aldosterone in healthy and sick subjects].
    Klinische Wochenschrift, 1968, Jul-15, Volume: 46, Issue:14

    Topics: Aldosterone; Edema; Glomerulonephritis; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Liv

1968
[A case of juvenile arterial hypertension associated with hypokalemia and low aldosterone secretion (Liddle syndrome)].
    Schweizerische medizinische Wochenschrift, 1968, May-11, Volume: 98, Issue:19

    Topics: Adolescent; Aldosterone; Female; Humans; Hypertension; Hypokalemia; Spironolactone; Triamterene

1968
Syndrome of idiopathic hyperkalaemia and hypertension with decreased plasma renin activity: effects on plasma renin and aldosterone of reducing the serum potassium level.
    The Medical journal of Australia, 1968, Dec-07, Volume: 2, Issue:23

    Topics: Adolescent; Aldosterone; Chlorothiazide; Corticosterone; Glomerular Filtration Rate; Humans; Hydroco

1968
[Aldosterone and arterial hypertension].
    L'Annee endocrinologique, 1968, Volume: 20

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal

1968
[Excretion of aldosterone in pregnancy hypertension].
    Pediatriia akusherstvo i ginekologiia, 1968, Volume: 6

    Topics: Adult; Aldosterone; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular

1968
[Pathological evaluation of adrenal cortical adenoma with essential hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1968, Volume: 26, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Female; Humans; Hypertension; Male; Midd

1968
Test for pathologic secretion of aldosterone.
    JAMA, 1968, Nov-25, Volume: 206, Issue:9

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diet; Humans; Hyperaldosteronism; Hyperplasia; Hypert

1968
[Clinical management of arterial hypertension at the Hôtel-Dieu de Montréal].
    Lyon medical, 1968, Nov-10, Volume: 220, Issue:45

    Topics: Aldosterone; Angiography; Antihypertensive Agents; Diet Therapy; Diuretics; Electrolytes; Histamine;

1968
Aldosterone and hypertension.
    Postgraduate medicine, 1969, Volume: 45, Issue:2

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia

1969
Intravenously administered chlorothiazide in diagnostic evaluation of hypertensive disease.
    Archives of internal medicine, 1969, Volume: 123, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Aldosterone; Blood Pre

1969
A concluding response.
    Archives of internal medicine, 1969, Volume: 123, Issue:2

    Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin

1969
Correlation of plasma renin activity and aldosterone secretion rate in hypertensive patients.
    Helvetica medica acta, 1969, Volume: 34, Issue:5

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension; Hyperten

1969
[The pathogenesis of hypertension and sinus tachycardia in human thallium intoxication].
    Archiv fur klinische Medizin, 1969, Volume: 216, Issue:1

    Topics: Adult; Aldosterone; Antidotes; Blood Pressure; Catecholamines; Heart Rate; Humans; Hypertension; Inj

1969
Deoxycorticosterone production in adrenal regeneration hypertension: in vitro vs. in vivo comparison.
    Endocrinology, 1969, Volume: 84, Issue:6

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Analysis of Variance; Animals; Blood Pressure; Body Weig

1969
Secretion of sodium and potassium by the parotid gland in essential hypertension.
    Southern medical journal, 1969, Volume: 62, Issue:4

    Topics: Adult; Aldosterone; Chlorides; Female; Humans; Hypertension; Male; Parotid Gland; Potassium; Saliva;

1969
[The importance of primary aldosteronism as cause of "essential" hypertension].
    Schweizerische medizinische Wochenschrift, 1969, Volume: 99, Issue:23

    Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Middle Aged; Potassium;

1969
[Hypokalemic metabolic alkalosis].
    Deutsche medizinische Wochenschrift (1946), 1969, Jul-11, Volume: 94, Issue:28

    Topics: Acid-Base Equilibrium; Adrenal Gland Diseases; Adrenocortical Hyperfunction; Adult; Aldosterone; Alk

1969
Salivary sodium-potassium ratio and plasma renin activity in hypertension.
    Circulation, 1969, Volume: 39, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Diet, Sodium-Restricted; Female; Humans; Hyper

1969
Non-tumorous "primary" aldosteronism. I. Type relieved by glucocorticoid (glucocorticoid-remediable aldosteronism).
    Canadian Medical Association journal, 1969, Jul-12, Volume: 101, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenalectomy; Adult; Aldosterone; Androgens

1969
Potassium loss with thiazide therapy.
    American heart journal, 1969, Volume: 78, Issue:1

    Topics: Aldosterone; Blood Gas Analysis; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Natriuresi

1969
Plasma renin activity in the diagnosis of primary aldosteronism: failure to distinguish primary aldosteronism from essential hypertension.
    Archives of internal medicine, 1969, Volume: 123, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Animals; Biological Assay; Blood Urea Nitrogen; Chlorot

1969
Secretion and turnover of aldosterone in various pathological states.
    Clinical science, 1969, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Aldosterone; Chronic Disease; Dehydration; Edema; Glomerulonephritis; Heart Failu

1969
[Effect of the biotron on the activity of aldosterone in hypertensive patients. (The sodium-potassium coefficient in the saliva)].
    Vrachebnoe delo, 1965, Volume: 4

    Topics: Aldosterone; Climate; Humans; Hypertension; Potassium; Saliva; Sodium

1965
[Studies on the secretion and metabolic clearance rates and the mean plasma concentration of aldosterone in man].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1965, Volume: 71

    Topics: Adult; Aged; Aldosterone; Female; Glomerulonephritis; Humans; Hypertension; Injections, Intravenous;

1965
The pharmacology and clinical use of rauwolfia, hydralazine, thiazides, and aldosterone antagonists in arterial hypertension.
    Progress in cardiovascular diseases, 1966, Volume: 8, Issue:4

    Topics: Aldosterone; Benzothiadiazines; Diuretics; Humans; Hydralazine; Hypertension; Phytotherapy; Plants,

1966
Relation between potassium balance and aldosterone secretion in normal subjects and in patients with hypertensive or renal tubular disease.
    The Journal of clinical investigation, 1966, Volume: 45, Issue:6

    Topics: Acidosis, Renal Tubular; Adrenal Gland Neoplasms; Adult; Aldosterone; Ethacrynic Acid; Female; Human

1966
[Determination of the plasma renin activity in 261 hypertensives].
    La Presse medicale, 1966, Sep-24, Volume: 74, Issue:40

    Topics: Aldosterone; Female; Humans; Hypertension; Male; Renin; Sodium

1966
The role of catecholamines in the pathogenesis of hypertension.
    Japanese circulation journal, 1966, Volume: 30, Issue:2

    Topics: Aldosterone; Humans; Hypertension; Norepinephrine; Sodium; Urine

1966
[The importance of aldosterone in the development of edema and hypertension].
    Klinicheskaia meditsina, 1966, Volume: 44, Issue:7

    Topics: Aldosterone; Edema; Humans; Hypertension

1966