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xylazine and Hypertension

xylazine has been researched along with Hypertension in 11 studies

Xylazine: An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
xylazine : A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"Xylazine was administered i."1.30Actions of xylazine in young swine. ( Castillo-Olivares, JL; Gómez de Segura, IA; Mascías, A; Santos, M; Steffey, EP; Tendillo, FJ, 1997)
" Although it was possible that the clinical findings in these horses may have resulted from use of an inadequate dosage of carfentanil or xylazine, or both, analysis of the results more likely indicated that domestic and exotic horses may respond differently to carfentanil, and domestic horses may not be a good model for use in studies of carfentanil."1.29Complications with the use of carfentanil citrate and xylazine hydrochloride to immobilize domestic horses. ( Carpenter, JW; Leith, DE; Shaw, ML, 1995)
"Hypertension was recorded in 11."1.28A retrospective survey of anaesthesia in horses with colic. ( Adams, JG; Cowgill, LM; Trim, CM; Ward, SL, 1989)
"Hydralazine treatment, which prevented the development of hypertension, attenuated the increased 3H overflow evoked by PNS in SHR."1.28Effect of chronically administered hydralazine on altered adrenergic neurotransmission mediated by presynaptic alpha- and beta-adrenoceptors in spontaneously hypertensive rats. ( Kato, H; Mochizuki, S; Takata, Y, 1990)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's3 (27.27)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Miller, DL1
Dou, C1
Raghavendran, K1
Dong, Z1
Bencze, M1
Behuliak, M1
Zicha, J1
Desjardins, JF1
Pourdjabbar, A1
Quan, A1
Leong-Poi, H1
Teichert-Kuliszewska, K1
Verma, S1
Parker, TG1
Shaw, ML1
Carpenter, JW1
Leith, DE1
Gómez de Segura, IA1
Tendillo, FJ1
Mascías, A1
Santos, M1
Castillo-Olivares, JL1
Steffey, EP1
Trim, CM1
Adams, JG1
Cowgill, LM1
Ward, SL1
van Gorp, AW1
Schenau, DS1
Hoeks, AP1
Boudier, HA1
de Mey, JG1
Reneman, RS1
Finch, L1
Takata, Y1
Mochizuki, S1
Kato, H1
Docherty, JR2
Warnock, P1

Other Studies

11 other studies available for xylazine and Hypertension

ArticleYear
The Influence of Xylazine and Clonidine on Lung Ultrasound-Induced Pulmonary Capillary Hemorrhage in Spontaneously Hypertensive Rats.
    Ultrasound in medicine & biology, 2021, Volume: 47, Issue:8

    Topics: Animals; Antihypertensive Agents; Capillaries; Clonidine; Hemorrhage; Hypertension; Lung; Male; Rats

2021
The impact of four different classes of anesthetics on the mechanisms of blood pressure regulation in normotensive and spontaneously hypertensive rats.
    Physiological research, 2013, Volume: 62, Issue:5

    Topics: Anesthetics; Anesthetics, Combined; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressur

2013
Lack of S100A1 in mice confers a gender-dependent hypertensive phenotype and increased mortality after myocardial infarction.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Anesthetics; Animals; Aorta; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Female;

2009
Complications with the use of carfentanil citrate and xylazine hydrochloride to immobilize domestic horses.
    Journal of the American Veterinary Medical Association, 1995, Mar-15, Volume: 206, Issue:6

    Topics: Analgesics, Opioid; Animals; Animals, Domestic; Fentanyl; Horse Diseases; Horses; Hypertension; Immo

1995
Actions of xylazine in young swine.
    American journal of veterinary research, 1997, Volume: 58, Issue:1

    Topics: Analgesics; Anesthetics; Animals; Behavior, Animal; Blood Pressure; Bradycardia; Cardiovascular Phys

1997
A retrospective survey of anaesthesia in horses with colic.
    Equine veterinary journal. Supplement, 1989, Issue:7

    Topics: Administration, Inhalation; Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthet

1989
In spontaneously hypertensive rats alterations in aortic wall properties precede development of hypertension.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:4

    Topics: Adrenergic alpha-Agonists; Age Factors; Anesthetics, Dissociative; Animals; Aorta, Thoracic; Blood P

2000
The central hypotensive action of clonidine and BAY 1470 in cats and rats.
    Clinical science and molecular medicine. Supplement, 1975, Volume: 2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; Cats; Clonidine; Heart Rate; Hypertension;

1975
Effect of chronically administered hydralazine on altered adrenergic neurotransmission mediated by presynaptic alpha- and beta-adrenoceptors in spontaneously hypertensive rats.
    Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:9

    Topics: Adrenergic Fibers; Aging; Animals; Blood Pressure; Drug Administration Schedule; Electric Stimulatio

1990
An investigation of alpha-adrenoceptor responsiveness in the vas deferens of spontaneously hypertensive rats.
    British journal of pharmacology, 1985, Volume: 86, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
An investigation of the effects of intravenous injection of the 5-hydroxytryptamine 2 receptor antagonists ketanserin and LY 53857 on blood pressure in anesthetized spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Blood Pressure; Ergolines; Heart Rate;

1989