thiosulfates has been researched along with Hypertension in 22 studies
Thiosulfates: Inorganic salts of thiosulfuric acid possessing the general formula R2S2O3.
thiosulfate(2-) : A divalent inorganic anion obtained by removal of both protons from thiosulfuric acid.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sodium thiosulfate, a reversible oxidation product of hydrogen sulfide, has vasodilating and anti-oxidative properties, making it an attractive agent to alleviate damaging effects of hypertension." | 7.96 | Sodium thiosulfate improves renal function and oxygenation in L-NNA-induced hypertension in rats. ( Feelisch, M; Joles, JA; Klooster, A; Minnion, M; Nguyen, ITN; van Goor, H; Verhaar, MC, 2020) |
| "Hydrogen sulfide (H2S) is a gaseous signalling molecule with antihypertensive properties." | 6.53 | Hydrogen sulfide in hypertension. ( Hillebrands, JL; Joles, JA; van den Born, JC; van Goor, H, 2016) |
| "Hypertension and proteinuria are important mediators of renal damage." | 5.40 | Sodium thiosulfate attenuates angiotensin II-induced hypertension, proteinuria and renal damage. ( Bachtler, M; Bos, EM; Frenay, AR; Hillebrands, JL; Koning, AM; Kwakernaak, AJ; Leuvenink, HG; Navis, G; Pasch, A; Snijder, PM; van den Berg, E; van Goor, H, 2014) |
| "Sodium thiosulfate, a reversible oxidation product of hydrogen sulfide, has vasodilating and anti-oxidative properties, making it an attractive agent to alleviate damaging effects of hypertension." | 3.96 | Sodium thiosulfate improves renal function and oxygenation in L-NNA-induced hypertension in rats. ( Feelisch, M; Joles, JA; Klooster, A; Minnion, M; Nguyen, ITN; van Goor, H; Verhaar, MC, 2020) |
| "Hydrogen sulfide (H2S) is a gaseous signalling molecule with antihypertensive properties." | 2.53 | Hydrogen sulfide in hypertension. ( Hillebrands, JL; Joles, JA; van den Born, JC; van Goor, H, 2016) |
| "Calciphylaxis is associated with a high mortality rate." | 1.43 | Survival, Risk Factors, and Effect of Treatment in 101 Patients With Calciphylaxis. ( Albright, RC; Bridges, AD; Claus, PL; Davis, MD; Dillon, JJ; El-Azhary, RA; El-Zoghby, ZM; Hickson, LJ; Kumar, R; McBane, RD; McCarthy, JT; McCarthy-Fruin, KA; McEvoy, MT; Patzelt, MT; Pittelkow, MR; Weaver, AL; Wetter, DA; Williams, AW, 2016) |
| "Hydrogen sulfide (H2S) is an endogenously produced gasotransmitter with cardioprotective properties." | 1.42 | Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats. ( de Boer, RA; Frenay, AR; Hillebrands, JL; Leuvenink, HG; Pasch, A; Snijder, PM; van Goor, H, 2015) |
| "ESRD was secondary to nephronophthisis (n = 1), membranoproliferative glomerulonephritis (n = 1), diabetic nephropathy (n = 1), and thrombotic microangiopathy (n = 1)." | 1.40 | Sodium thiosulphate treatment of uraemic tumoral calcinosis. ( Bardin, T; Cohen-Solal, M; Ea, HK; Lioté, F; Malbos, S; Trout, H; Urena-Torres, P, 2014) |
| "Hypertension and proteinuria are important mediators of renal damage." | 1.40 | Sodium thiosulfate attenuates angiotensin II-induced hypertension, proteinuria and renal damage. ( Bachtler, M; Bos, EM; Frenay, AR; Hillebrands, JL; Koning, AM; Kwakernaak, AJ; Leuvenink, HG; Navis, G; Pasch, A; Snijder, PM; van den Berg, E; van Goor, H, 2014) |
| " Infusion of SNP mixed with thiosulphate showed no such accumulation of cyanide in any patient, irrespective of dosage level and duration." | 1.26 | Cyanide toxicity of sodium nitroprusside in therapeutic use with and without sodium thiosulphate. ( Busse, J; Gross, R; Loeschcke, G; Pasch, T; Schulz, V, 1982) |
| "Gold salt treatment does not influence the blood pressure of normotensive rats but transiently lowers the blood pressure of spontaneously hypertensive rats." | 1.26 | Influence of the selective prostaglandin biosynthesis inhibitor, gold, on the arterial pressure of normotensive and spontaneously hypertensive rats. ( Block, HU; Förster, W; Hoffmann, P, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (59.09) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (22.73) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Terstappen, F | 1 |
| Clarke, SM | 1 |
| Joles, JA | 3 |
| Ross, CA | 1 |
| Garrett, MR | 1 |
| Minnion, M | 2 |
| Feelisch, M | 2 |
| Goor, HV | 1 |
| Sasser, JM | 1 |
| Lely, AT | 1 |
| Nguyen, ITN | 1 |
| Klooster, A | 1 |
| Verhaar, MC | 1 |
| van Goor, H | 4 |
| Singh, A | 1 |
| Tandon, S | 1 |
| Tandon, C | 1 |
| Malbos, S | 1 |
| Urena-Torres, P | 1 |
| Cohen-Solal, M | 1 |
| Trout, H | 1 |
| Lioté, F | 1 |
| Bardin, T | 1 |
| Ea, HK | 1 |
| Snijder, PM | 2 |
| Frenay, AR | 2 |
| de Boer, RA | 1 |
| Pasch, A | 2 |
| Hillebrands, JL | 3 |
| Leuvenink, HG | 2 |
| Koning, AM | 1 |
| Bachtler, M | 1 |
| Kwakernaak, AJ | 1 |
| van den Berg, E | 1 |
| Bos, EM | 1 |
| Navis, G | 1 |
| van den Born, JC | 1 |
| McCarthy, JT | 1 |
| El-Azhary, RA | 1 |
| Patzelt, MT | 1 |
| Weaver, AL | 1 |
| Albright, RC | 1 |
| Bridges, AD | 1 |
| Claus, PL | 1 |
| Davis, MD | 1 |
| Dillon, JJ | 1 |
| El-Zoghby, ZM | 1 |
| Hickson, LJ | 1 |
| Kumar, R | 1 |
| McBane, RD | 1 |
| McCarthy-Fruin, KA | 1 |
| McEvoy, MT | 1 |
| Pittelkow, MR | 1 |
| Wetter, DA | 1 |
| Williams, AW | 1 |
| SAVIO, O | 1 |
| DAUR, W | 1 |
| BECK, D | 1 |
| SIEGENTHALER, W | 1 |
| Schulz, V | 4 |
| Roth, B | 1 |
| Gross, R | 1 |
| Pasch, T | 1 |
| Busse, J | 1 |
| Loeschcke, G | 2 |
| Hoffmann, P | 2 |
| Förster, W | 2 |
| Block, HU | 1 |
| Kobayashi, H | 1 |
| Hasuda, K | 1 |
| Taniguchi, S | 1 |
| Baba, T | 1 |
| Mordvintsev, PI | 1 |
| Putintsev, MD | 1 |
| Galagan, ME | 1 |
| Oranovskaia, EV | 1 |
| Medvedev, OS | 1 |
| Sophian, J | 1 |
| Sasaki, C | 1 |
| Perini, A | 1 |
| Bossi, M | 1 |
| Bozzi, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Human Amniotic Mesenchymal Stem Cells (hAMSCs) on Wound Healing in Uremic Calciphylaxis Patients: an Open Label Single Arm Study[NCT04592640] | 7 participants (Anticipated) | Interventional | 2018-09-17 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thiosulfates and Hypertension
| Article | Year |
|---|---|
An update on vascular calcification and potential therapeutics.
Topics: Atherosclerosis; Calcimimetic Agents; Calcium; Denosumab; Diabetes Mellitus; Diphosphonates; Dyslipi | 2021 |
Hydrogen sulfide in hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Humans; Hydrogen Sulfide; Hypertension; Thiosulfat | 2016 |
20 other studies available for thiosulfates and Hypertension
| Article | Year |
|---|---|
Sodium Thiosulfate in the Pregnant Dahl Salt-Sensitive Rat, a Model of Preeclampsia.
Topics: Animals; Blood Pressure; Female; Fetal Growth Retardation; Fetus; Hypertension; Kidney; Placenta; Pr | 2020 |
Sodium thiosulfate improves renal function and oxygenation in L-NNA-induced hypertension in rats.
Topics: Animals; Blood Pressure; Enzyme Inhibitors; Hypertension; Kidney; NG-Nitroarginine Methyl Ester; Nit | 2020 |
Sodium thiosulphate treatment of uraemic tumoral calcinosis.
Topics: Aged; Calcinosis; Comorbidity; Female; Humans; Hypertension; Incidence; Kidney Diseases; Kidney Fail | 2014 |
Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Models, Anim | 2015 |
Sodium thiosulfate attenuates angiotensin II-induced hypertension, proteinuria and renal damage.
Topics: Angiotensin II; Animals; Base Sequence; DNA Primers; Hypertension; Kidney; Proteinuria; Rats; Rats, | 2014 |
Survival, Risk Factors, and Effect of Treatment in 101 Patients With Calciphylaxis.
Topics: Adult; Aged; Aged, 80 and over; Calciphylaxis; Debridement; Diabetes Mellitus; Female; Glomerular Fi | 2016 |
[Clearances of sodium hyposulfite and endogenous creatinine (modified Rehberg test) and its value in the study of renal function in various phases of so-called hypertensive disease].
Topics: Creatinine; Dithionite; Humans; Hypertension; Kidney Function Tests; Sodium; Thiosulfates | 1953 |
Magnesium and hypertension.
Topics: Humans; Hypertension; Magnesium Sulfate; Thiosulfates | 1955 |
[RENAL FUNCTION IN CARDIAC INSUFFICIENCY].
Topics: Heart Failure; Hypertension; Hypertension, Renal; Kidney; Kidney Function Tests; Natriuresis; p-Amin | 1965 |
[The therapeutic scope of sodium nitroprusside].
Topics: Cyanides; Ferricyanides; Humans; Hypertension; Nitroprusside; Thiosulfate Sulfurtransferase; Thiosul | 1983 |
Detoxification of cyanide in a new-born child.
Topics: Antidotes; Ferricyanides; Humans; Hypertension; Infant, Newborn; Infant, Newborn, Diseases; Male; Ni | 1982 |
Cyanide toxicity of sodium nitroprusside in therapeutic use with and without sodium thiosulphate.
Topics: Adolescent; Adult; Aged; Antidotes; Cyanides; Female; Ferricyanides; Humans; Hypertension; Injection | 1982 |
[The antihypertensive action of the selective inhibitor of prostaglandin biosynthesis, gold, on spontaneously hypertensive rats].
Topics: Animals; Antihypertensive Agents; Gold; Hypertension; Male; Prostaglandin Antagonists; Rats; Thiosul | 1977 |
Influence of the selective prostaglandin biosynthesis inhibitor, gold, on the arterial pressure of normotensive and spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Gold; Hypertension; Indomethacin; Kidney Medulla; Prostaglandins; Prostagla | 1978 |
Therapeutic efficacy of two-route chemotherapy using cis-diamminedichloroplatinum(II) and its antidote, sodium thiosulfate, combined with the angiotensin-II-induced hypertension method in a rat uterine tumor.
Topics: Angiotensin II; Animals; Blood Pressure; Carcinoma, Transitional Cell; Cisplatin; Female; Hypertensi | 1991 |
[Hypotensive activity of dinitrosyl complexes of iron and proteins in anesthetized animals].
Topics: Anesthesia; Antihypertensive Agents; Blood Proteins; Ferrous Compounds; Hypertension; Male; Molecula | 1988 |
Hypotensive efficacy of a mixed solution of 0.1% sodium nitroprusside and 1% sodium thiosulphate.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Cyanides; Drug Therapy, Combination; Female; Ferri | 1985 |
Pre-eclamptic toxaemia in smokers.
Topics: Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Smoking; Thiocyanates; Thiosulfates | 1968 |
[Study on corticosterone secretion rate with reference to normal and hypertensive subjects].
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Aldosterone; Body Constitut | 1966 |
[Behavior of clearances of sodium thiosulfate and creatinine during posterior pituitary oliguria].
Topics: Adolescent; Adult; Aged; Anuria; Arthritis, Rheumatoid; Bronchopneumonia; Coronary Disease; Creatini | 1967 |