4-diphenylacetoxy-1,1-dimethylpiperidinium has been researched along with Hypertension in 5 studies
4-diphenylacetoxy-1,1-dimethylpiperidinium: muscarinic receptor antagonist; RN given refers to parent cpd; do not confuse abbreviation 4-DAMP with a similar cpd which does not contain dimethyl groups
4-DAMP(1+) : A quaternary ammonium salt obtained by formal methylation of the tertiary amino function of 4-diphenylacetoxy-N-methylpiperidine.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent evidence has suggested that pilocarpine (ACh receptor agonist) injected peripherally may act centrally producing salivation and hypertension." | 7.74 | Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake. ( Borella, TL; Colombari, DS; De Luca, LA; Menani, JV, 2008) |
| "Recent evidence has suggested that pilocarpine (ACh receptor agonist) injected peripherally may act centrally producing salivation and hypertension." | 3.74 | Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake. ( Borella, TL; Colombari, DS; De Luca, LA; Menani, JV, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Menegatti, R | 1 |
| Carvalho, FS | 1 |
| Lião, LM | 1 |
| Villavicencio, B | 1 |
| Verli, H | 1 |
| Mourão, AA | 1 |
| Xavier, CH | 1 |
| Castro, CH | 1 |
| Pedrino, GR | 1 |
| Franco, OL | 1 |
| Oliveira-Silva, I | 1 |
| Ashpole, NM | 1 |
| Silva, ON | 1 |
| Costa, EA | 1 |
| Fajemiroye, JO | 1 |
| Borella, TL | 1 |
| De Luca, LA | 1 |
| Colombari, DS | 1 |
| Menani, JV | 1 |
| Kanaya, T | 1 |
| Okatani, H | 1 |
| Hagiwara, Y | 1 |
| Fukumori, R | 1 |
| Goshima, Y | 1 |
| Kubo, T | 1 |
| Hendriks, MG | 1 |
| Pfaffendorf, M | 1 |
| van Zwieten, PA | 1 |
| Sim, MK | 1 |
| Manjeet, S | 1 |
5 other studies available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and Hypertension
| Article | Year |
|---|---|
Novel choline analog 2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)ethan-1-ol produces sympathoinhibition, hypotension, and antihypertensive effects.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Atropine; Blood Pressure; Heart Rate; Hypertensio | 2019 |
Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake.
Topics: Animals; Blood Pressure; Diamines; Drinking Behavior; Heart Rate; Hypertension; Injections, Intraven | 2008 |
Projections from the caudal part to the rostral part of the lateral septal area mediate blood pressure increase.
Topics: Animals; Blood Pressure; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Fluoresc | 2003 |
Characterization of the muscarinic receptors in the mesenteric vascular bed of spontaneously hypertensive rats.
Topics: Animals; Atropine; Benzodiazepinones; Endothelium, Vascular; Hypertension; Male; Mesenteric Artery, | 1993 |
Muscarinic receptors in the aortae of normo- and hypertensive rats: a binding study.
Topics: Acetylcholine; Animals; Aorta; Atropine; Binding, Competitive; Endothelium, Vascular; Guanylyl Imido | 1993 |