mepivacaine has been researched along with Hypertension in 8 studies
Mepivacaine: A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
mepivacaine : A piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Fatal cardiac arrhythmias occurred in, respectively, 3 of 11, 2 of 12, and 2 of 13 conscious sheep infused with bupivacaine, levobupivacaine, and ropivacaine; in 1 of 9 with prilocaine, electromechanical dissociation (followed by polymorphic ventricular tachycardia) caused death." | 3.74 | The effects of general anesthesia on the central nervous and cardiovascular system toxicity of local anesthetics. ( Copeland, SE; Gu, XQ; Ladd, LA; Mather, LE, 2008) |
| "An increase in blood pressure, accompanied by atrial fibrillation, agitation, incomprehensible shouts and loss of consciousness, was observed in an elderly, ASA classification group II, cardiovascularly medicated male, 12 min after performance of axillary block with mepivacaine 850 mg containing adrenaline 0." | 3.70 | An unusual toxic reaction to axillary block by mepivacaine with adrenaline. ( Koscielniak-Nielsen, ZJ, 1998) |
| " A 61-year old woman received the left stellate ganglion block with 5 ml of 1% mepivacaine for her left facial palsy." | 3.69 | [A case of severe hypertension caused by stellate ganglion block in a patient with facial palsy]. ( Kimura, T; Komatsu, T; Shimada, Y; Yokota, S, 1996) |
| "3% mepivacaine has quick onset, ideal anesthetic effect and little side effect on cardiovascular system." | 2.73 | [Efficacy and safety of 3% mepivacaine hydrochloride injection for oral local anesthesia]. ( Cao, D; Ding, S; Wu, YN; Zhu, YQ, 2008) |
| "Propranolol is a commonly used drug; of new and refilled prescriptions, it ranked no." | 1.27 | Hypertensive response to levonordefrin in a patient receiving propranolol: report of case. ( Mito, RS; Yagiela, JA, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, S | 1 |
| Zhu, YQ | 1 |
| Wu, YN | 1 |
| Cao, D | 1 |
| Copeland, SE | 1 |
| Ladd, LA | 1 |
| Gu, XQ | 1 |
| Mather, LE | 1 |
| Hartung, HJ | 1 |
| Osswald, PM | 1 |
| Tolksdorf, W | 1 |
| Bender, HJ | 1 |
| Lutz, H | 1 |
| Yokota, S | 1 |
| Komatsu, T | 1 |
| Kimura, T | 1 |
| Shimada, Y | 1 |
| Koscielniak-Nielsen, ZJ | 1 |
| Mito, RS | 1 |
| Yagiela, JA | 1 |
| Pearson, AC | 1 |
| Labovitz, AJ | 1 |
| Kern, MJ | 1 |
| Sehhati, G | 1 |
| Frey, R | 1 |
| Mildner, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficiency of Intravenous Lidocaine to Reduce Coughing and the Hemodynamic Changes Associated to Tracheal Extubation[NCT03731429] | Phase 4 | 144 participants (Anticipated) | Interventional | 2019-04-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for mepivacaine and Hypertension
| Article | Year |
|---|---|
[Efficacy and safety of 3% mepivacaine hydrochloride injection for oral local anesthesia].
Topics: Anesthesia, Local; Anesthetics, Local; Epinephrine; Humans; Hypertension; Lidocaine; Mepivacaine; Mo | 2008 |
7 other studies available for mepivacaine and Hypertension
| Article | Year |
|---|---|
The effects of general anesthesia on the central nervous and cardiovascular system toxicity of local anesthetics.
Topics: Acid-Base Equilibrium; Amides; Anesthetics, Inhalation; Anesthetics, Local; Animals; Arrhythmias, Ca | 2008 |
[Incidence of complications with plexus anaesthesia; a computer-assisted evaluation (author's transl)].
Topics: Anesthesia, Conduction; Arrhythmias, Cardiac; Cervical Plexus; Computers; Humans; Hypertension; Hypo | 1982 |
[A case of severe hypertension caused by stellate ganglion block in a patient with facial palsy].
Topics: Anesthetics, Local; Autonomic Nerve Block; Facial Paralysis; Female; Humans; Hypertension; Mepivacai | 1996 |
An unusual toxic reaction to axillary block by mepivacaine with adrenaline.
Topics: Absorption; Aged; Akathisia, Drug-Induced; Anesthetics, Local; Anti-Arrhythmia Agents; Antihypertens | 1998 |
Hypertensive response to levonordefrin in a patient receiving propranolol: report of case.
Topics: Adult; Anesthesia, Dental; Blood Pressure; Drug Interactions; Female; Humans; Hypertension; Mepivaca | 1988 |
Accelerated hypertension complicated by myocardial infarction after use of a local anesthetic/vasoconstrictor preparation.
Topics: Anesthetics, Local; Humans; Hypertension; Male; Mepivacaine; Middle Aged; Myocardial Infarction; Nor | 1987 |
[Complications of regional anaesthesia and their treatment (author's transl)].
Topics: Adrenal Cortex Hormones; Anesthesia, Local; Apnea; Barbiturates; Bradycardia; Bupivacaine; Diagnosis | 1973 |