midodrine has been researched along with Hypertension in 13 studies
Midodrine: An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.
midodrine : An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Midodrine, a drug used to treat symptomatic orthostatic hypotension, may cause or exacerbate supine hypertension." | 7.71 | Supine hypertension during general anesthesia in a patient taking midodrine. ( Chaimberg, KH; Travis, KW, 2002) |
| "The comparative effects of droxidopa and midodrine on standing systolic blood pressure (sSBP) and risk of supine hypertension in patients with neurogenic orthostatic hypotension (NOH) are unknown." | 4.98 | Standing and Supine Blood Pressure Outcomes Associated With Droxidopa and Midodrine in Patients With Neurogenic Orthostatic Hypotension: A Bayesian Meta-analysis and Mixed Treatment Comparison of Randomized Trials. ( Chen, JJ; Dashtipour, K; Han, Y; Hauser, RA; Portillo, I; Tang, J, 2018) |
| "Midodrine, a drug used to treat symptomatic orthostatic hypotension, may cause or exacerbate supine hypertension." | 3.71 | Supine hypertension during general anesthesia in a patient taking midodrine. ( Chaimberg, KH; Travis, KW, 2002) |
| "Particularly debilitating is neurogenic orthostatic hypotension (nOH) caused by deficient neurotransmission of norepinephrine, which is the primary neurotransmitter released at sympathetic peripheral vascular nerve terminals in response to orthostatic stress." | 2.61 | Chemical pharmacotherapy for the treatment of orthostatic hypotension. ( Cheshire, WP, 2019) |
| "Fludrocortisone did not increase angiotensinogen in these mice, implying that the rise in angiotensinogen in the siRNA-treated rats must have depended on the liver, most likely reflecting diminished cleavage by renin." | 1.72 | Conventional Vasopressor and Vasopressor-Sparing Strategies to Counteract the Blood Pressure-Lowering Effect of Small Interfering RNA Targeting Angiotensinogen. ( Danser, AHJ; Daugherty, A; Foster, D; Garrelds, IM; Hoorn, EJ; Lu, HS; Mirabito Colafella, KM; Nioi, P; Ren, L; Uijl, E; van Veghel, R; Ye, D, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Uijl, E | 1 |
| Ye, D | 1 |
| Ren, L | 1 |
| Mirabito Colafella, KM | 1 |
| van Veghel, R | 1 |
| Garrelds, IM | 1 |
| Lu, HS | 1 |
| Daugherty, A | 1 |
| Hoorn, EJ | 1 |
| Nioi, P | 1 |
| Foster, D | 1 |
| Danser, AHJ | 1 |
| Wegner Wippel, C | 1 |
| Deshpande, H | 1 |
| Patwa, H | 1 |
| Peixoto, AJ | 1 |
| Cannom, DS | 1 |
| Chen, JJ | 1 |
| Han, Y | 1 |
| Tang, J | 1 |
| Portillo, I | 1 |
| Hauser, RA | 1 |
| Dashtipour, K | 1 |
| Cheshire, WP | 2 |
| Sadeghpour, M | 1 |
| Bunick, CG | 1 |
| Robinson, DM | 1 |
| Galan, A | 1 |
| Tigelaar, RE | 1 |
| Imaeda, S | 1 |
| Tanabe, N | 1 |
| Takane, K | 1 |
| Yokoyama, K | 1 |
| Tanno, Y | 1 |
| Yamamoto, I | 1 |
| Ohkido, I | 1 |
| Yokoo, T | 1 |
| Wong, LY | 1 |
| Wong, A | 1 |
| Robertson, T | 1 |
| Burns, K | 1 |
| Roberts, M | 1 |
| Isbister, GK | 1 |
| Lagi, A | 1 |
| Spini, S | 1 |
| Chaimberg, KH | 1 |
| Travis, KW | 1 |
| Achem, SR | 1 |
| Sandroni, P | 1 |
| Benarroch, EE | 1 |
| Wijdicks, EF | 1 |
3 reviews available for midodrine and Hypertension
| Article | Year |
|---|---|
Standing and Supine Blood Pressure Outcomes Associated With Droxidopa and Midodrine in Patients With Neurogenic Orthostatic Hypotension: A Bayesian Meta-analysis and Mixed Treatment Comparison of Randomized Trials.
Topics: Antiparkinson Agents; Bayes Theorem; Blood Pressure; Droxidopa; Humans; Hypertension; Hypotension, O | 2018 |
Chemical pharmacotherapy for the treatment of orthostatic hypotension.
Topics: Blood Pressure; Comorbidity; Droxidopa; Humans; Hypertension; Hypotension, Orthostatic; Midodrine | 2019 |
Clinostatic hypertension and orthostatic hypotension.
Topics: Antihypertensive Agents; Autonomic Nervous System; Blood Pressure; Humans; Hypertension; Hypotension | 2010 |
10 other studies available for midodrine and Hypertension
| Article | Year |
|---|---|
Conventional Vasopressor and Vasopressor-Sparing Strategies to Counteract the Blood Pressure-Lowering Effect of Small Interfering RNA Targeting Angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Fludrocortisone; Hypertension; Mice; Midod | 2022 |
Neurogenic orthostatic hypotension after treatment with sorafenib.
Topics: Humans; Hypertension; Hypotension, Orthostatic; Male; Midodrine; Sorafenib; Vascular Endothelial Gro | 2022 |
Management of coexistent neurogenic orthostatic hypotension and supine hypertension.
Topics: Accidental Falls; Central Nervous System Agents; Droxidopa; Drug Substitution; Female; Humans; Hyper | 2019 |
Midodrine-induced acute generalized exanthematous pustulosis.
Topics: Acute Generalized Exanthematous Pustulosis; Humans; Hypertension; Male; Middle Aged; Midodrine; Vaso | 2014 |
Dialysate temperature adjustment as an effective treatment for baroreflex failure syndrome in hemodialysis patient.
Topics: Aged; Baroreflex; Carotid Sinus; Cold Temperature; Dialysis Solutions; Dizziness; Droxidopa; Enteral | 2014 |
Severe Hypertension and Bradycardia Secondary to Midodrine Overdose.
Topics: Adrenergic alpha-1 Receptor Antagonists; Blood Pressure; Bradycardia; Drug Overdose; Female; Glasgow | 2017 |
Supine hypertension during general anesthesia in a patient taking midodrine.
Topics: Adult; Amputation, Surgical; Anesthesia, General; Blood Pressure; Diabetes Mellitus, Type 1; Humans; | 2002 |
Clinical history.
Topics: Blood Pressure; Chest Pain; Clonazepam; Female; Heart Rate; Humans; Hypertension; Incidence; Middle | 2004 |
Midodrine marketed for orthostatic hypotension.
Topics: Adrenergic alpha-Agonists; Humans; Hypertension; Hypotension, Orthostatic; Midodrine; Prodrugs | 1996 |
Caudate hemorrhage as a possible complication of midodrine-induced supine hypertension.
Topics: Aged; Caudate Nucleus; Cerebral Hemorrhage; Humans; Hypertension; Hypotension, Orthostatic; Male; Mi | 2001 |