Page last updated: 2024-10-19

nitroxyl and Hypertension

nitroxyl has been researched along with Hypertension in 6 studies

nitroxyl: hydroxamic acid oxidized to nitroxyl free radical
nitroxyl : A nitrogen oxoacid consisting of an oxygen atom double-bonded to an NH group.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"Nitroxyl anion (HNO) has recently become an emerging candidate in vascular regulation."1.46Nitroxyl Anion Mediates Relaxation in Mesenteric Arteries from Angiotensin II Hypertensive Mice. ( Labazi, H; Tostes, RC; Webb, RC; Wynne, BM, 2017)
"Hypertension is a disorder affecting millions worldwide, and is a leading cause of death and debilitation in the United States."1.38Aorta from angiotensin II hypertensive mice exhibit preserved nitroxyl anion mediated relaxation responses. ( Labazi, H; Tostes, RC; Webb, RC; Wynne, BM, 2012)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Kamynina, A1
Guttzeit, S1
Eaton, P1
Cuello, F1
Wynne, BM2
Labazi, H2
Tostes, RC2
Webb, RC2
Irvine, JC1
Ravi, RM1
Kemp-Harper, BK1
Widdop, RE1
Tan, NP1
Taylor, MK1
Bottle, SE1
Wright, CE1
Ziogas, J1
White, JM1
Schiesser, CH1
Jani, NV1
Soule, BP1
Hyodo, F1
Matsumoto, K1
Simone, NL1
Cook, JA1
Krishna, MC1
Mitchell, JB1

Reviews

1 review available for nitroxyl and Hypertension

ArticleYear
Therapeutic and clinical applications of nitroxide compounds.
    Antioxidants & redox signaling, 2007, Volume: 9, Issue:10

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Humans; Hypertension; Magnetic Resonance Im

2007

Other Studies

5 other studies available for nitroxyl and Hypertension

ArticleYear
Nitroxyl Donor CXL-1020 Lowers Blood Pressure by Targeting C195 in Cyclic Guanosine-3',5'-Monophosphate-Dependent Protein Kinase I.
    Hypertension (Dallas, Tex. : 1979), 2022, Volume: 79, Issue:5

    Topics: Animals; Blood Pressure; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependen

2022
Nitroxyl Anion Mediates Relaxation in Mesenteric Arteries from Angiotensin II Hypertensive Mice.
    Current vascular pharmacology, 2017, Volume: 16, Issue:1

    Topics: 4-Aminopyridine; Acetylcholine; Angiotensin II; Animals; Disease Models, Animal; Hypertension; Male;

2017
Nitroxyl donors retain their depressor effects in hypertension.
    American journal of physiology. Heart and circulatory physiology, 2013, Sep-15, Volume: 305, Issue:6

    Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Male; Nitric Oxide Donors;

2013
Aorta from angiotensin II hypertensive mice exhibit preserved nitroxyl anion mediated relaxation responses.
    Pharmacological research, 2012, Volume: 65, Issue:1

    Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Dose-Response

2012
Novel paramagnetic AT1 receptor antagonists.
    Chemical communications (Cambridge, England), 2011, Nov-28, Volume: 47, Issue:44

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Ca

2011