sodium-hypochlorite and Hypertension

The purpose of this study was a toxicological interpretation of exposure to chlorine with unusual course. Medical, clinical and court records, as well as reviews of the literature, served as the basis for this interpretation. The first case of poisoning concerns a 52-year-old man who for a short time (probably several hours), during the industrial cleaning of facilities with sodium hypochlorite, was exposed to chlorine in a presumed high concentration. The man was obese and suffered from hypertension and moderate atherosclerosis, and therefore could be more susceptible to the toxic effects of chlorine. After exposure no pulmonary edema or symptoms typical for acute respiratory distress syndrome were present. The second case concerns the chronic poisoning of a 56-year-old man who worked for eight years, 8 h a day, 5 days a week, in a room which was next to a chlorination room. In this chamber technical sodium hypochlorite was stored and dosed. In both cases, determining a cause and effect relationship between exposure to toxic and allergic agents in the form of active chlorine, and the onset of symptoms may be difficult. The findings described above in the first and second case are particularly important in cases of compensation claims and may have a completely different etiology than previously described in medical literature.

Topics: Asthma; Chlorine; Coronary Artery Disease; Disinfectants; Forensic Pathology; Forensic Toxicology; Humans; Hypertension; Lung; Male; Middle Aged; Obesity; Occupational Exposure; Pulmonary Emphysema; Sodium Hypochlorite; Time Factors

A 52-year-old woman had a fatal intracerebral hemorrhage after dental manipulation. Normotensive in the past, the initial blood pressure was high but rapidly returned to normal. Necropsy showed no vascular malformation or evidence of hypertensive vascular disease. Clinical and experimental data show that stimulation of trigeminal fibers can cause important changes in blood pressure and pulse.

Topics: Cerebral Hemorrhage; Female; Humans; Hypertension; Middle Aged; Sodium Hypochlorite; Therapeutic Irrigation; Trigeminal Neuralgia

Topics: Color; Hematuria; Humans; Hypertension; Male; Methyldopa; Middle Aged; Sodium Hypochlorite; Urine