cirazoline has been researched along with Hypertension in 11 studies
cirazoline: posseses agonist properties at alpha-adrenoreceptor sites; RN given refers to parent cpd
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypertension is often present in the diabetic individual and it is known to aggravate the vascular complications associated with diabetes." | 5.29 | Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats. ( Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA, 1996) |
| "Cirazoline did not produce a significant depolarisation in blood vessels of either normotensive or hypertensive rats." | 1.32 | Effects of chloride substitution on electromechanical responses in the pulmonary artery of Dahl normotensive and hypertensive rats. ( Bieger, D; Duggan, JA; Tabrizchi, R, 2004) |
| "Hypertension is often present in the diabetic individual and it is known to aggravate the vascular complications associated with diabetes." | 1.29 | Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats. ( Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA, 1996) |
| "Hypertension was associated with enhanced pressor response, whereas the diabetic state counteracted this effect." | 1.29 | Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats. ( Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adeagbo, AS | 2 |
| Joshua, IG | 1 |
| Falkner, C | 1 |
| Matheson, PJ | 1 |
| Bieger, D | 1 |
| Duggan, JA | 2 |
| Tabrizchi, R | 5 |
| Parai, K | 2 |
| Triggle, CR | 1 |
| Beenen, OH | 3 |
| Pfaffendorf, M | 4 |
| van Zwieten, PA | 4 |
| Mathy, MJ | 2 |
| Mertens, MJ | 1 |
| Batink, HD | 1 |
| Thoolen, MJ | 1 |
| Miller, CR | 1 |
| Chiu, AT | 1 |
| Timmermans, PB | 1 |
11 other studies available for cirazoline and Hypertension
| Article | Year |
|---|---|
Tempol, an antioxidant, restores endothelium-derived hyperpolarizing factor-mediated vasodilation during hypertension.
Topics: Acetylcholine; Animals; Antioxidants; Benzimidazoles; Biological Factors; Blood Pressure; Calcium Ch | 2003 |
Effects of chloride substitution on electromechanical responses in the pulmonary artery of Dahl normotensive and hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Chlorides; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; | 2004 |
Impact of nitric oxide synthase inhibitor and chloride channel antagonist on mesenteric vascular conductance in anesthetized Dahl normotensive and hypertensive rats.
Topics: Animals; Blood Pressure; Chloride Channels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fem | 2005 |
Effects of chloride substitution in isolated mesenteric blood vessels from Dahl normotensive and hypertensive rats.
Topics: Animals; Chlorides; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Enz | 2005 |
The effects of perfusion rate and NG-nitro-L-arginine methyl ester on cirazoline- and KCl-induced responses in the perfused mesenteric arterial bed of rats.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Hype | 1994 |
Contractile responses to various inotropic agents in isolated hearts obtained from hypertensive diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Azepines; Blood Glucose; Blood Pressure; Brimoni | 1996 |
Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Brimonidine Tartrate; Calcium | 1996 |
Effect of nitric oxide synthase inhibitor N(omega) nitro-L-arginine methyl ester on relaxant responses to calcium channel antagonists in isolated aortic rings from Dahl normotensive and hypertensive rats.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Diltiazem; Enzyme Inhibitors; Female; Hypertensi | 2002 |
Depressed inotropic response to alpha 1-adrenoceptor agonists in hearts from spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Depression, Chemical; Hypertension; Imidazoles; In Vitro Techniq | 1991 |
Effect of calcium entry blockers on blood pressure and vasoconstrictor responses to alpha-1 adrenoceptor stimulation in conscious spontaneously hypertensive rats.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Binding, Competitive; Blo | 1987 |