Page last updated: 2024-10-15

8-oxyguanine

Description

8-oxyguanine: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

8-oxoguanine : An oxopurine that is guanine which is substituted by an oxo group at position 8. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID135498233
CHEBI ID44605
SCHEMBL ID22143
MeSH IDM0177886

Synonyms (12)

Synonym
1h-purine-6,8-dione, 2-amino-
8-oxyguanine
8-oxoguanine
2-amino-1h-purine-6,8-dione
CHEBI:44605
82014-86-6
8-oxo-guanine
SCHEMBL22143
DTXSID60231515
UBKVUFQGVWHZIR-UHFFFAOYSA-N
6-hydroxy-2-imino-8,9-dihydro-2h-purin-8-one
Q4644284
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
oxopurine
2-aminopurinesAny aminopurine having the amino substituent at the 2-position.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (5)

PathwayProteinsCompounds
DNA Repair25547
Base Excision Repair3523
Base-Excision Repair, AP Site Formation1716
Depurination107
Cleavage of the damaged purine47

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (11.11%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (88.89%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]