fenclonine has been researched along with Hypertension in 7 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sved, AF | 1 |
| Van Itallie, CM | 1 |
| Fernstrom, JD | 1 |
| McCarty, R | 1 |
| Chiueh, CC | 1 |
| Kopin, IJ | 1 |
| Browning, RA | 1 |
| Bramlet, DG | 1 |
| Myers, JH | 1 |
| Bundman, MC | 1 |
| Smith, ML | 1 |
| Jarrott, B | 1 |
| McQueen, A | 1 |
| Graf, L | 1 |
| Louis, WJ | 1 |
| Laborit, H | 1 |
| Desplaces, N | 1 |
| Ogawa, M | 1 |
| Yamori, Y | 1 |
| De Jong, W | 1 |
| Yamabe, H | 1 |
| Lovenberg, W | 1 |
| Sjoerdsma, A | 1 |
7 other studies available for fenclonine and Hypertension
| Article | Year |
|---|---|
Studies on the antihypertensive action of L-tryptophan.
Topics: Amino Acids; Animals; Antihypertensive Agents; Blood Pressure; Drug Interactions; Fenclonine; Fluoxe | 1982 |
Differential behavioral responses of spontaneously hypertensive (SHR) and normotensive (WKY) rats to d-amphetamine.
Topics: Animals; Apomorphine; Behavior, Animal; Blood Pressure; Dextroamphetamine; Dopamine; Dose-Response R | 1980 |
Failure to produce blood pressure changes following pharmacological or surgical depletion of brain serotonin in the spontaneously hypertensive rat.
Topics: 5,7-Dihydroxytryptamine; Animals; Blood Pressure; Brain; Brain Stem; Dihydroxytryptamines; Fenclonin | 1981 |
Serotonin levels in vascular tissue and the effects of a serotonin synthesis inhibitor on blood pressure in hypertensive rats.
Topics: Animals; Blood Pressure; Blood Vessels; Depression, Chemical; Fenclonine; Hypertension; Myocardium; | 1975 |
[Action of parachlorophenylalanine on arterial hypertension induced by the use of an unavoidable plantar electric shock].
Topics: Animals; Behavior, Animal; Disease Models, Animal; Electroshock; Fenclonine; Hypertension; Rats; Ser | 1977 |
Interaction between noradrenergic and serotonergic mechanisms on the central regulation of blood pressure in the rat: a study using experimental central hypertension produced by chemical lesions of the locus coeruleus.
Topics: 5,6-Dihydroxytryptamine; Animals; Blood Pressure; Brain Chemistry; Desipramine; Fenclonine; Heart Ra | 1978 |
Effects of L-dopa and inhibitors of decarboxylase and monoamine oxidase on brain noradrenaline levels and blood pressure in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain Chemistry; Brain Stem; Carboxy-Lyases; Cresols; Dihydroxyphenylalanin | 1972 |