phenytoin has been researched along with Hypertension in 34 studies
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Women with a singleton pregnancy in vertex presentation between 32 and 42 weeks' gestation who required induction of labor for either preeclampsia, preeclampsia superimposed on chronic hypertension, or transient hypertension were randomized to receive either magnesium sulfate or phenytoin (Dilantin) for seizure prophylaxis." | 9.08 | Does magnesium sulfate affect the length of labor induction in women with pregnancy-associated hypertension? ( Atkinson, MW; Guinn, D; Hauth, JC; Owen, J, 1995) |
| " Anticonvulsant prophylaxis with phenytoin for eclampsia has been recommended, but there are virtually no data to support its efficacy." | 9.08 | A comparison of magnesium sulfate with phenytoin for the prevention of eclampsia. ( Cunningham, FG; Leveno, KJ; Lucas, MJ, 1995) |
| "Twenty-two patients with eclampsia were randomly allocated to receive either intravenous phenytoin sodium or intravenous magnesium sulphate." | 9.06 | Phenytoin sodium and magnesium sulphate in the management of eclampsia. ( Dommisse, J, 1990) |
| "Phenytoin is a well-tolerated alternative to magnesium sulfate for seizure prophylaxis in the patient with mild pregnancy-induced hypertension." | 6.67 | Magnesium sulfate versus phenytoin for seizure prophylaxis in pregnancy-induced hypertension. ( Adams, HR; Appleton, MP; Gold, WR; Knight, AB; Kuehl, TJ; Raebel, MA, 1991) |
| "Women with a singleton pregnancy in vertex presentation between 32 and 42 weeks' gestation who required induction of labor for either preeclampsia, preeclampsia superimposed on chronic hypertension, or transient hypertension were randomized to receive either magnesium sulfate or phenytoin (Dilantin) for seizure prophylaxis." | 5.08 | Does magnesium sulfate affect the length of labor induction in women with pregnancy-associated hypertension? ( Atkinson, MW; Guinn, D; Hauth, JC; Owen, J, 1995) |
| " Anticonvulsant prophylaxis with phenytoin for eclampsia has been recommended, but there are virtually no data to support its efficacy." | 5.08 | A comparison of magnesium sulfate with phenytoin for the prevention of eclampsia. ( Cunningham, FG; Leveno, KJ; Lucas, MJ, 1995) |
| "Twenty-two patients with eclampsia were randomly allocated to receive either intravenous phenytoin sodium or intravenous magnesium sulphate." | 5.06 | Phenytoin sodium and magnesium sulphate in the management of eclampsia. ( Dommisse, J, 1990) |
| "Phenytoin or an identically appearing placebo was administered in a double-blind fashion to 20 patients with mild essential hypertension." | 5.04 | Transient hypotensive effect of phenytoin in man. ( Solomon, HS; Sullivan, JM, 1977) |
| "A 21-year-old white man, with propionic acidemia and seizures treated with phenytoin and carbamazepine, was started on isradipine for essential hypertension." | 3.71 | Phenytoin/isradipine interaction causing severe neurologic toxicity. ( Cachat, F; Tufro, A, 2002) |
| "Phenytoin is a well-tolerated alternative to magnesium sulfate for seizure prophylaxis in the patient with mild pregnancy-induced hypertension." | 2.67 | Magnesium sulfate versus phenytoin for seizure prophylaxis in pregnancy-induced hypertension. ( Adams, HR; Appleton, MP; Gold, WR; Knight, AB; Kuehl, TJ; Raebel, MA, 1991) |
| "Propofol was infused for 24 hours and then was stopped to allow continuing neurological assessment." | 1.37 | Accidental intraventricular administration of phenytoin through an external ventricular drain: case report. ( Macneil, C; McConnell, P, 2011) |
| "When phenytoin was discontinued, blood pressure temporarily normalized." | 1.31 | [Refractory arterial hypertension and the use of anticonvulsant drugs. Case report]. ( Downey, P; Fajuri, A; Valdés, G, 2001) |
| "Cerebral palsy was not diagnosed in any infant of a hypertensive mother compared with five of the controls." | 1.30 | Maternal hypertension and neurodevelopmental outcome in very preterm infants. ( Burns, YR; Gray, PH; King, JF; Mohay, HA; O'Callaghan, MJ, 1998) |
| "A majority of seizure patients with "subtherapeutic" mean plasma phenytoin levels were identified as noncompliant using our measures." | 1.27 | A general method of compliance assessment using centralized pharmacy records. Description and validation. ( Fihn, SD; Inui, TS; Koepsell, TD; Steiner, JF, 1988) |
| "22 patients with severe preeclampsia-eclampsia were treated in our Intensive Care Unit from 1972 to 1978." | 1.26 | [Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)]. ( Larsen, R; Radke, J; Turner, E, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (64.71) | 18.7374 |
| 1990's | 7 (20.59) | 18.2507 |
| 2000's | 3 (8.82) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Squair, JW | 1 |
| Phillips, AA | 1 |
| Harmon, M | 1 |
| Krassioukov, AV | 1 |
| McConnell, P | 1 |
| Macneil, C | 1 |
| Cachat, F | 1 |
| Tufro, A | 1 |
| DeLashaw, MR | 1 |
| Vizioli, TL | 1 |
| Counselman, FL | 1 |
| Siegel, M | 1 |
| Lee, SL | 1 |
| Peress, NS | 1 |
| Kotovskaia, ES | 1 |
| Erina, EV | 1 |
| Merryfield, DW | 1 |
| Ayers, TG | 1 |
| Wilkinson, CA | 1 |
| Williams, RB | 1 |
| Larsen, R | 1 |
| Turner, E | 1 |
| Radke, J | 1 |
| Aldrete, JA | 1 |
| Franatovic, Y | 1 |
| de la Torre, R | 1 |
| murgía-Suarez, JJ | 1 |
| Aldrete, J | 1 |
| Atkinson, MW | 1 |
| Guinn, D | 1 |
| Owen, J | 1 |
| Hauth, JC | 1 |
| Lucas, MJ | 1 |
| Leveno, KJ | 1 |
| Cunningham, FG | 1 |
| Bauer, TM | 1 |
| Brühwiler, J | 1 |
| Aschwanden, M | 1 |
| Wagner, S | 1 |
| Schwander, J | 1 |
| Gray, PH | 1 |
| O'Callaghan, MJ | 1 |
| Mohay, HA | 1 |
| Burns, YR | 1 |
| King, JF | 1 |
| Gatt, SP | 1 |
| Downey, P | 1 |
| Fajuri, A | 1 |
| Valdés, G | 1 |
| Sullivan, JM | 1 |
| Solomon, HS | 1 |
| Miyazaki, T | 1 |
| Araki, Y | 1 |
| Dadkar, NK | 1 |
| Gupte, RD | 1 |
| Dohadwalla, AN | 1 |
| Barrillon, A | 1 |
| Grand, A | 1 |
| Lew, GM | 1 |
| Appleton, MP | 1 |
| Kuehl, TJ | 1 |
| Raebel, MA | 1 |
| Adams, HR | 1 |
| Knight, AB | 1 |
| Gold, WR | 1 |
| Dommisse, J | 1 |
| Steiner, JF | 1 |
| Koepsell, TD | 1 |
| Fihn, SD | 1 |
| Inui, TS | 1 |
| Glogner, P | 1 |
| Cantor, FK | 1 |
| Rydén, L | 1 |
| Hjalmarson, A | 1 |
| Wasir, H | 1 |
| Werkö, L | 1 |
| Raisfeld, IH | 1 |
| Yoshimasu, F | 1 |
| Kurland, LT | 1 |
| Elveback, LR | 1 |
| Cohen, H | 1 |
| Langendorf, R | 1 |
| Pick, A | 1 |
| Vohra, JK | 1 |
| Fischer, KC | 1 |
| Wilson, WP | 1 |
| Glatt, MM | 1 |
| George, HR | 1 |
| Frisch, EP | 1 |
| Pritchard, JA | 1 |
| Scott, DE | 1 |
| Whalley, PJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT04994886] | 8 participants (Anticipated) | Interventional | 2021-06-08 | Recruiting | |||
| The Effects of Spinal Cord Stimulation on Autonomic Function in People With Spinal Cord Injury[NCT03924388] | 46 participants (Anticipated) | Interventional | 2020-02-01 | Not yet recruiting | |||
| Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT05044923] | 8 participants (Anticipated) | Interventional | 2021-12-31 | Recruiting | |||
| Epidural Electrical Stimulation to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury[NCT05111093] | 20 participants (Anticipated) | Interventional | 2021-11-29 | Recruiting | |||
| Hydroxychloroquine Exposure in Systemic Lupus Erythematosus (SLE)[NCT03802188] | 3,700 participants (Anticipated) | Observational | 2018-05-09 | Recruiting | |||
| Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients[NCT01671501] | 614 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for phenytoin and Hypertension
| Article | Year |
|---|---|
Clinical management of established pre-eclampsia and gestational hypertension: an anaesthetist's perspective.
Topics: Acute Kidney Injury; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Obstetrical; Anticonvu | 1999 |
[Abnormal steroid hormone metabolism during administration of various drugs].
Topics: Alcohol Drinking; Animals; Barbiturates; Estradiol; Humans; Hydrocortisone; Hypertension; Male; Meta | 1979 |
[Incompatibility and interference of the major cardiologic drugs. Their undesirable effects].
Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Bradycardia; Cardiac Glyc | 1976 |
Clinical pharmacology of drug interactions.
Topics: Antihypertensive Agents; Blood Coagulation Disorders; Cardiovascular Diseases; Coumarins; Drug Inter | 1973 |
8 trials available for phenytoin and Hypertension
| Article | Year |
|---|---|
[Trial of using neurotropic preparations (difenin and pyrroxan) for the purpose of prophylactic anticrisis treatment of hypertension].
Topics: Adrenergic alpha-Antagonists; Anticonvulsants; Antihypertensive Agents; Brain; Clinical Trials as To | 1982 |
Postponement of operations: its prevention in patients found to be mildly hypertensive.
Topics: Anesthesia; Blood Pressure; Heart Rate; Humans; Hypertension; Intraoperative Complications; Phenytoi | 1980 |
Does magnesium sulfate affect the length of labor induction in women with pregnancy-associated hypertension?
Topics: Adolescent; Adult; Anticonvulsants; Cesarean Section; Chi-Square Distribution; Chronic Disease; Fema | 1995 |
A comparison of magnesium sulfate with phenytoin for the prevention of eclampsia.
Topics: Adolescent; Adult; Analysis of Variance; Eclampsia; Female; Humans; Hypertension; Infant, Newborn; M | 1995 |
Transient hypotensive effect of phenytoin in man.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Hyperte | 1977 |
Magnesium sulfate versus phenytoin for seizure prophylaxis in pregnancy-induced hypertension.
Topics: Adult; Female; Humans; Hypertension; Magnesium Sulfate; Phenytoin; Pregnancy; Pregnancy Complication | 1991 |
Phenytoin sodium and magnesium sulphate in the management of eclampsia.
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Drug Evaluation; Eclampsia; Female; Humans; Hyp | 1990 |
Evaluation of chlormethiazole in treatment for alcohol withdrawal syndrome. Results of a controlled trial.
Topics: Alcoholism; Chlormethiazole; Clinical Trials as Topic; Depression; Female; Humans; Hypertension; Hyp | 1966 |
22 other studies available for phenytoin and Hypertension
| Article | Year |
|---|---|
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Emergency management of autonomic dysreflexia with neurologic complications.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consc | 2016 |
Accidental intraventricular administration of phenytoin through an external ventricular drain: case report.
Topics: Anticonvulsants; Drug Administration Routes; Humans; Hypertension; Male; Medical Errors; Middle Aged | 2011 |
Phenytoin/isradipine interaction causing severe neurologic toxicity.
Topics: Acidosis; Adult; Anticonvulsants; Antihypertensive Agents; Calcium Channel Blockers; Drug Interactio | 2002 |
Headache and seizure in a young woman postpartum.
Topics: Adult; Anticoagulants; Cerebral Angiography; Female; Headache; Humans; Hypertension; Phenytoin; Puer | 2005 |
The epidemiology of drug-induced systemic lupus erythematosus.
Topics: Adolescent; Adult; Aged; Child; Epilepsy; Female; Heart Diseases; Humans; Hydralazine; Hypertension; | 1967 |
Clinical pharmacy services in a rehabilitation facility.
Topics: Contract Services; Drug Information Services; Financial Management; Hospital Bed Capacity, 300 to 49 | 1983 |
[Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)].
Topics: Acute Kidney Injury; Adolescent; Adult; Brain Edema; Critical Care; Diazepam; Dihydralazine; Eclamps | 1980 |
Comparison of phenytoin and conventional drug therapy in the treatment of mild hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Phenytoin | 1980 |
[Neurocysticercosis].
Topics: Albendazole; Animals; Antibodies, Helminth; Brain; Brain Diseases; Croatia; Cysticercosis; Diagnosis | 1994 |
Maternal hypertension and neurodevelopmental outcome in very preterm infants.
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Case-Control Studies; Cerebral Palsy; Child, Presch | 1998 |
[Refractory arterial hypertension and the use of anticonvulsant drugs. Case report].
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Resistance; Humans; Hypertension; Mal | 2001 |
Effect of diphenylhydantoin on blood pressure of spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Hypertension; Hypothalamus; Norepinephrine; Phenytoin; Rats | 1979 |
Increased hypothalamic norepinephrine in genetically hypertensive rats following administration of diphenylhydantoin (38407).
Topics: Animals; Cerebellum; Circadian Rhythm; Hypertension; Hypothalamus; Norepinephrine; Phenytoin; Stimul | 1975 |
A general method of compliance assessment using centralized pharmacy records. Description and validation.
Topics: Computers; Drug Prescriptions; Drug Therapy; Hospital Bed Capacity, 300 to 499; Hospitals, Veterans; | 1988 |
A general method of compliance assessment using centralized pharmacy records. Description and validation.
Topics: Computers; Drug Prescriptions; Drug Therapy; Hospital Bed Capacity, 300 to 499; Hospitals, Veterans; | 1988 |
A general method of compliance assessment using centralized pharmacy records. Description and validation.
Topics: Computers; Drug Prescriptions; Drug Therapy; Hospital Bed Capacity, 300 to 499; Hospitals, Veterans; | 1988 |
A general method of compliance assessment using centralized pharmacy records. Description and validation.
Topics: Computers; Drug Prescriptions; Drug Therapy; Hospital Bed Capacity, 300 to 499; Hospitals, Veterans; | 1988 |
[Unfavorable and problematic drug combinations. IV].
Topics: Amphetamine; Ataxia; Bone Marrow; Cerebral Hemorrhage; Depression, Chemical; Dicumarol; Dihydroxyphe | 1970 |
Phenytoin treatment of thalamic pain.
Topics: Humans; Hypertension; Infarction; Male; Middle Aged; Neurologic Manifestations; Pain; Peripheral Ner | 1972 |
Effects of a long-acting antiarrhythmic agent--QX-572--on therapy resistant ventricular tachyarrhythmias.
Topics: Acute Disease; Adult; Aged; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; | 1974 |
Tic douloureux in Rochester, Minnesota, 1945-1969.
Topics: Adult; Age Factors; Aged; Analgesics; Carbamazepine; Ethanol; Female; Follow-Up Studies; Humans; Hyp | 1972 |
Intermittent parasystole--mechanism of protection.
Topics: Aged; Aminosalicylic Acids; Arrhythmias, Cardiac; Arteriosclerosis; Cerebrovascular Disorders; Coron | 1973 |
Cardiovascular abnormalities following tricyclic antidepressant drug overdosage.
Topics: Acidosis; Antidepressive Agents; Arrhythmias, Cardiac; Bicarbonates; Bradycardia; Heart Rate; Humans | 1974 |
Methylphenidate and the hyperkinetic state.
Topics: Ataxia; Child; Drug Synergism; Feeding and Eating Disorders; Humans; Hyperkinesis; Hypertension; Met | 1971 |
Maternal folate deficiency and pregnancy wastage. IV. Effects of folic acid supplements, anticonvulsants, and oral contraceptives.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anemia, Macrocytic; Anemia, Sickle Cell; Anemia, | 1971 |