ebselen has been researched along with Hypertension in 3 studies
ebselen : A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Excerpt | Relevance | Reference |
---|---|---|
" We sought to investigate whether long-term administration of seleno-glutathione peroxidase mimic ebselen (PZ51) would have a protective effect on cortical neurons in SHRsp, and, if so, the possible mechanisms of this effect." | 5.33 | Protective effect of antioxidant ebselen (PZ51) on the cerebral cortex of stroke-prone spontaneously hypertensive rats. ( Liu, LS; Sui, H; Wang, PH; Wang, W, 2005) |
"To investigate whether extrinsic antioxidant seleno-glutathione peroxidase mimic ebselen (PZ51) can protect endothelium and vascular structure of stroke-prone spontaneously hypertensive rats (SHRsp) during the chronic process of hypertension." | 3.73 | Effect of glutathione peroxidase mimic ebselen (PZ51) on endothelium and vascular structure of stroke-prone spontaneously hypertensive rats. ( Liu, LS; Sui, H; Wang, PH; Wang, W, 2005) |
"Rats treated with Ebselen and exposed to CIH displayed a significant reduction in 3-NT-ir levels (60." | 1.43 | Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation. ( Arias, P; Del Rio, R; Iturriaga, R; Moya, EA; Oyarce, MP; Varela, C, 2016) |
" We sought to investigate whether long-term administration of seleno-glutathione peroxidase mimic ebselen (PZ51) would have a protective effect on cortical neurons in SHRsp, and, if so, the possible mechanisms of this effect." | 1.33 | Protective effect of antioxidant ebselen (PZ51) on the cerebral cortex of stroke-prone spontaneously hypertensive rats. ( Liu, LS; Sui, H; Wang, PH; Wang, W, 2005) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (66.67) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Moya, EA | 1 |
Arias, P | 1 |
Varela, C | 1 |
Oyarce, MP | 1 |
Del Rio, R | 1 |
Iturriaga, R | 1 |
Sui, H | 2 |
Wang, W | 2 |
Wang, PH | 2 |
Liu, LS | 2 |
3 other studies available for ebselen and Hypertension
Article | Year |
---|---|
Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation.
Topics: Animals; Azoles; Blood Pressure; Carotid Body; Diastole; Hypertension; Hypoxia; Isoindoles; Male; Ne | 2016 |
Protective effect of antioxidant ebselen (PZ51) on the cerebral cortex of stroke-prone spontaneously hypertensive rats.
Topics: Animals; Antioxidants; Azoles; Blood Pressure; Blotting, Western; Body Weight; Cerebral Cortex; Hype | 2005 |
Effect of glutathione peroxidase mimic ebselen (PZ51) on endothelium and vascular structure of stroke-prone spontaneously hypertensive rats.
Topics: Animals; Antioxidants; Azoles; Blood Pressure; Blotting, Western; Body Weight; Carotid Arteries; End | 2005 |