Page last updated: 2024-11-07

dehydroepiandrosterone and Hypertension

dehydroepiandrosterone has been researched along with Hypertension in 89 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"To demonstrate that calcium channel blockers can improve insulin resistance clinically, we investigated the effects of the calcium channel blockers, amlodipine, manidipine and cilnidipine on serum levels of steroid hormones and insulin."9.11Effects of the long-acting calcium channel blockers, amlodipine, manidipine and cilnidipine on steroid hormones and insulin resistance in hypertensive obese patients. ( Miyachi, Y; Ueshiba, H, 2004)
"In 1994 the Massachusetts Male Aging Study described an inverse correlation of the serum levels of dehydroepiandrosterone sulfate (DHEAS) and the incidence of erectile dysfunction (ED)."9.09Dehydroepiandrosterone in the treatment of erectile dysfunction in patients with different organic etiologies. ( Marberger, M; Märk, I; Pycha, A; Reiter, WJ; Schatzl, G; Zeiner, A, 2001)
"This cross-sectional study assessed the association of serum dehydroepiandrosterone levels with the risk of diabetic retinopathy in patients with type 2 diabetes mellitus in China."8.31Low serum dehydroepiandrosterone levels are associated with diabetic retinopathy in patients with type 2 diabetes mellitus. ( Feng, W; Huang, Y; Liu, M; Qiao, J; Xu, N; Zhang, X, 2023)
"We investigated the effects of the calcium channel blocker amlodipine besilate on serum levels of adrenal androgens and insulin in 20 men with essential hypertension and obesity (age: 51."7.71Effects of amlodipine on serum levels of adrenal androgens and insulin in hypertensive men with obesity. ( Miyachi, Y; Tsuboi, K; Ueshiba, H, 2001)
" We tested the hypothesis that dehydroepiandrosterone (DHEA), which prevents dexamethasone-induced hypertension in rats, may block adrenocorticotrophin (ACTH) hypertension, which has been presumed due to corticosterone excess."7.69Dehydroepiandrosterone does not prevent adrenocorticotrophin-induced hypertension in conscious rats. ( Li, M; Martin, A; Wen, C; Whitworth, JA, 1996)
"Alterations in the concentration of plasma dehydroepiandrosterone sulfate (DHEA-S) and cortisol in patients with essential hypertension (EH) were investigated."7.66A study on dehydroepiandrosterone sulfate in patients with essential hypertension. ( Hatano, M; Honda, M; Tsuchiya, M, 1982)
"An inhibitor of adrenal steroid biosynthesis, aminoglutethimide, was administered to seven patients with low renin essential hypertension, and the antihypertensive action of the drug was compared with its effects on adrenal steroid production."7.66Effect of aminoglutethimide on blood pressure and steroid secretion in patients with low renin essential hypertension. ( Bartter, FC; Franklin, RB; Gill, JR; McMurtry, RJ; Mitchell, JR; Snodgrass, WR; Taylor, AA, 1978)
"The excretion rates and precursors of the 3-sulfate and glucuronide conjugates of 16 beta-hydroxydehydroepiandrosterone (16 beta-OH DHEA) were measured in normotensive controls and in patients with normal and low renin essential hypertension."7.65Origin of urinary 16 beta-hydroxydehydroepiandrosterone in essential hypertension. ( Genest, J; Guthrie, GP; Kuchel, O; Messeril, FH; Nowaczynski, W, 1977)
"Dehydroepiandrosterone (DHEA) is an endogenous steroid having a wide variety of biological and biochemical effects."5.28Dehydroepiandrosterone prevents dexamethasone-induced hypertension in rats. ( Kalimi, M; Opoku, J; Qureshi, D; Regelson, W; Shafagoj, Y, 1992)
"To demonstrate that calcium channel blockers can improve insulin resistance clinically, we investigated the effects of the calcium channel blockers, amlodipine, manidipine and cilnidipine on serum levels of steroid hormones and insulin."5.11Effects of the long-acting calcium channel blockers, amlodipine, manidipine and cilnidipine on steroid hormones and insulin resistance in hypertensive obese patients. ( Miyachi, Y; Ueshiba, H, 2004)
"In 1994 the Massachusetts Male Aging Study described an inverse correlation of the serum levels of dehydroepiandrosterone sulfate (DHEAS) and the incidence of erectile dysfunction (ED)."5.09Dehydroepiandrosterone in the treatment of erectile dysfunction in patients with different organic etiologies. ( Marberger, M; Märk, I; Pycha, A; Reiter, WJ; Schatzl, G; Zeiner, A, 2001)
" The author's own findings and the data available in the literature indicate that the androgens dehydroepiandrosterone and dehydroepiandrosterone sulfate that are secreted in the reticular area play an important role in ensuring the body's full stable adaptation to stress and simultaneously preventing stress-associated abnormalities, such as atherosclerosis, diabetes, immunodefficiency, hypertension, allergies, and cancer."4.80[Dehydroepiandrosterone, reticular area of adrenal cortex and resistance to stress and disease]. ( Obut, TA, 1998)
"This cross-sectional study assessed the association of serum dehydroepiandrosterone levels with the risk of diabetic retinopathy in patients with type 2 diabetes mellitus in China."4.31Low serum dehydroepiandrosterone levels are associated with diabetic retinopathy in patients with type 2 diabetes mellitus. ( Feng, W; Huang, Y; Liu, M; Qiao, J; Xu, N; Zhang, X, 2023)
" Dehydroepiandrosterone (DHEA) protects against cardiovascular diseases, but results among previous studies have been inconsistent."3.83Dehydroepiandrosterone-sulfate is associated with cardiovascular reactivity to stress in women. ( Hirokawa, K; Imano, H; Iso, H; Kajiura, M; Kitamura, A; Kiyama, M; Nagayoshi, M; Ohira, T; Okada, T, 2016)
"After adjusting for age, race/ethnicity, and lifestyle factors, baseline serum estradiol (E(2)), total and bioavailable testosterone (T), dehydroepiandrosterone (DHEA) were each positively associated and sex-hormone binding globulin (SHBG) was inversely associated with risk of hypertension."3.78Endogenous sex hormones, blood pressure change, and risk of hypertension in postmenopausal women: the Multi-Ethnic Study of Atherosclerosis. ( Cook, NR; Folsom, AR; Gapstur, SM; Ouyang, P; Szklo, M; Wang, L, 2012)
"We investigated the effects of the calcium channel blocker amlodipine besilate on serum levels of adrenal androgens and insulin in 20 men with essential hypertension and obesity (age: 51."3.71Effects of amlodipine on serum levels of adrenal androgens and insulin in hypertensive men with obesity. ( Miyachi, Y; Tsuboi, K; Ueshiba, H, 2001)
" We tested the hypothesis that dehydroepiandrosterone (DHEA), which prevents dexamethasone-induced hypertension in rats, may block adrenocorticotrophin (ACTH) hypertension, which has been presumed due to corticosterone excess."3.69Dehydroepiandrosterone does not prevent adrenocorticotrophin-induced hypertension in conscious rats. ( Li, M; Martin, A; Wen, C; Whitworth, JA, 1996)
"Alterations in the concentration of plasma dehydroepiandrosterone sulfate (DHEA-S) and cortisol in patients with essential hypertension (EH) were investigated."3.66A study on dehydroepiandrosterone sulfate in patients with essential hypertension. ( Hatano, M; Honda, M; Tsuchiya, M, 1982)
"An inhibitor of adrenal steroid biosynthesis, aminoglutethimide, was administered to seven patients with low renin essential hypertension, and the antihypertensive action of the drug was compared with its effects on adrenal steroid production."3.66Effect of aminoglutethimide on blood pressure and steroid secretion in patients with low renin essential hypertension. ( Bartter, FC; Franklin, RB; Gill, JR; McMurtry, RJ; Mitchell, JR; Snodgrass, WR; Taylor, AA, 1978)
"To assess placental and fetoplacental function, 50 mg of dehydroepiandrosterone sulfate was administered intravenously to 11 normal obstetric patients at 35 to 40 weeks and to 36 high-risk patients at 35 to 43 weeks of pregnancy."3.65Dehydroepiandrosterone sulfate loading test in the diagnosis of complicated pregnancies. ( Finn, A; Osathanondh, R; Tulchinsky, D, 1976)
"16beta-Hydroxydehydroepiandrosterone (16beta-OH-DHEA) and related C19-steroids have recently been reported to be etiologic in low-renin essential hypertension."3.65Mineralocorticoid activity of 16beta-hydroxydehydroepiandrosterone and related steroids. ( Gomez-Sanchez, C; Gruber, GM; Higgins, JR; Holland, OB; Kaplan, NM; Mathieu, R; Milewich, L, 1976)
"A previously unidentified mineralocorticoid, 16beta-hydroxydehydroepiandrosterone (16beta OH-DHEA) has recently been isolated from urine extracts of patients with low-renin hypertension and reported to possess one-fortieth the mineralocorticoid potency of aldosterone by bioassay."3.65Interaction of 16beta-hydroxydehydroepiandrosterone with renal mineralocorticoid receptors. ( Gomez-Sanchez, C; Higgins, JR; Holland, OB; Kaplan, NM; Kem, DC; Wambach, G, 1977)
"The excretion rates and precursors of the 3-sulfate and glucuronide conjugates of 16 beta-hydroxydehydroepiandrosterone (16 beta-OH DHEA) were measured in normotensive controls and in patients with normal and low renin essential hypertension."3.65Origin of urinary 16 beta-hydroxydehydroepiandrosterone in essential hypertension. ( Genest, J; Guthrie, GP; Kuchel, O; Messeril, FH; Nowaczynski, W, 1977)
"Benfluorex treatment lowered diastolic and systolic blood pressures and improved glucose tolerance in both age groups."2.68Effects of insulin reduction with benfluorex on serum dehydroepiandrosterone (DHEA), DHEA sulfate, and blood pressure in hypertensive middle-aged and elderly men. ( Beer, NA; Beer, RM; Colombo, C; Jakubowicz, DJ; Nestler, JE, 1995)
"Nitrendipine treatment 1) lowered fasting serum insulin from 265 +/- 24 to 194 +/- 22 pmol/L (P < 0."2.67Effects of nitrendipine on glucose tolerance and serum insulin and dehydroepiandrosterone sulfate levels in insulin-resistant obese and hypertensive men. ( Arocha, IR; Beer, NA; Beer, RM; Jakubowicz, DJ; Nestler, JE, 1993)
"Amlodipine treatment 1) lowered fasting serum insulin (from 273 +/- 19 to 200 +/- 17 pmol/L; P < 0."2.67The calcium channel blocker amlodipine raises serum dehydroepiandrosterone sulfate and androstenedione, but lowers serum cortisol, in insulin-resistant obese and hypertensive men. ( Beer, NA; Beer, RM; Jakubowicz, DJ; Nestler, JE, 1993)
"Diltiazem treatment was associated with reductions in fasting serum insulin levels in both the men (from 91 +/- 14 to 56 +/- 12 pmol/L; P < 0."1.29Disparate effects of insulin reduction with diltiazem on serum dehydroepiandrosterone sulfate levels in obese hypertensive men and women. ( Beer, NA; Beer, RM; Jakubowicz, DJ; Nestler, JE, 1994)
"Dehydroepiandrosterone (DHEA) is an endogenous steroid having a wide variety of biological and biochemical effects."1.28Dehydroepiandrosterone prevents dexamethasone-induced hypertension in rats. ( Kalimi, M; Opoku, J; Qureshi, D; Regelson, W; Shafagoj, Y, 1992)

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-199063 (70.79)18.7374
1990's14 (15.73)18.2507
2000's6 (6.74)29.6817
2010's5 (5.62)24.3611
2020's1 (1.12)2.80

Authors

AuthorsStudies
Zhang, X1
Huang, Y1
Xu, N1
Feng, W1
Qiao, J1
Liu, M1
Novakovic, A1
Zukic, E1
Gazibera, B1
Gojak, R1
Hirokawa, K1
Ohira, T1
Nagayoshi, M1
Kajiura, M1
Imano, H1
Kitamura, A1
Kiyama, M1
Okada, T1
Iso, H1
Peredo, HA1
Mayer, M1
Faya, IR1
Puyó, AM1
Carranza, A1
Herman, WA1
Seńko, A1
Korczowska, I1
Łacka, K1
Bhuiyan, S1
Fukunaga, K1
Mieczkowska, J1
Mosiewicz, J1
Sak, J1
Grzybowski, A1
Terlecki, P1
Barud, W1
Kwaśniewski, W1
Tutka, P1
Wang, L1
Szklo, M1
Folsom, AR1
Cook, NR1
Gapstur, SM1
Ouyang, P1
BRETAN, M1
SZABO, Z1
JAKAB, L1
BALAZSI, I1
KOELBEL, F2
FREGOROVA, I1
SONKA, J5
GREGOROVA, I3
Ueshiba, H2
Miyachi, Y2
Halberg, F1
Parker, CR2
Hankins, GD1
Carr, BR2
Leveno, KJ1
Gant, NF7
MacDonald, PC7
New, MI1
Levine, LS1
Haruyama, K1
Yamazaki, M1
Toki, T1
Fukuchi, S2
Tsuchiya, M1
Honda, M1
Hatano, M1
Guthrie, GP2
Kotchen, TA1
Kotchen, JM1
Carroll, JE1
Goodfriend, TL1
Simpson, ER1
Bilheimer, DW1
Leveno, K1
Yamaji, T1
Ishibashi, M1
Katayama, S1
Kosaka, K3
Benassi, L1
Debiasi, D1
Terzolo, M1
Osella, G1
Alì, A1
Reimondo, G1
Borretta, G1
Magro, GP1
Luceri, S1
Paccotti, P1
Angeli, A1
Nestler, JE5
Beer, NA5
Jakubowicz, DJ5
Colombo, C1
Beer, RM5
Nathan, L1
Gilstrap, LC1
Theorell, T1
Ahlberg-Hulten, G1
Jodko, M1
Sigala, F1
de la Torre, B1
Arocha, IR1
Li, M1
Wen, C1
Martin, A1
Whitworth, JA1
Sandrini, R1
Ribeiro, RC1
DeLacerda, L1
Obut, TA1
Roth, GS1
Ingram, DK1
Lane, MA1
Szathmári, M1
Vásárhelyi, B1
Reusz, G1
Tulassay, T1
Tsuboi, K1
Reiter, WJ1
Schatzl, G1
Märk, I1
Zeiner, A1
Pycha, A1
Marberger, M1
Sekihara, H3
Osawa, N2
Sennett, JA3
Brown, RD1
Island, DP1
Yarbro, LR2
Watson, JT1
Slaton, PE1
Hollifield, JW1
Liddle, GW4
Korda, AR1
Challis, JJ1
Anderson, AB1
Turnbull, AC1
Madden, JD4
Siiteri, PK2
Tulchinsky, D1
Osathanondh, R1
Finn, A1
Chand, S2
Worley, RJ5
Strong, JD1
Lee, PA1
Kelly, MR1
Wallin, JD1
Gomez-Sanchez, C2
Holland, OB3
Higgins, JR2
Mathieu, R1
Gruber, GM1
Milewich, L2
Kaplan, NM2
Melby, JC2
Dale, SL1
Wambach, G1
Kem, DC1
Otokida, K1
Minamizawa, S1
Matsui, G1
Sugawara, T1
Kimura, T1
Nowaczynski, W4
Messeril, FH1
Kuchel, O3
Genest, J4
Anisimov, VE1
Taylor, AA1
Mitchell, JR1
Bartter, FC1
Snodgrass, WR1
McMurtry, RJ1
Gill, JR1
Franklin, RB1
Gabbe, SG1
Hagerman, DD1
Gomez-Sanchez, CE1
Welt, SI1
Crenshaw, MC1
Everett, RB1
Ojima, M1
Cedard, L1
Bedin, M1
Leblond, J1
Tanguy, G1
Kaminski, M1
Kumagai, A1
Tamura, Y1
McKenna, TJ1
Nowaczynksi, W1
Richardson, K1
Shafagoj, Y1
Opoku, J1
Qureshi, D1
Regelson, W1
Kalimi, M1
Amemiya, T1
Kawahara, R1
Yoshino, M1
Komori, K1
Hirata, Y1
Hughes, GS1
Mathur, RS1
Margolius, HS1
Mavoungou, D1
Nowaczynski, M1
Wilkins, GE1
Fung, K1
Crofton, NE1
Vasdev, S1
Longerich, L1
Johnson, E1
Brent, D1
Gault, MH1
Talbert, LM1
Easterling, WE1
Ratner, AIu1
Krasnova, VM1
Denisova, MG1
Bilialov, MSh1
Efimova, OA1
Chizhova, EI1
Abyzéova, TA1
Vertlib, IaM1
Sharshun, NN1
Fragachan, F1
Silah, J1
Millette, B1
Shao, A1
Farquhar, JW1
Larsen, AE1
Miftakhova, AS1
Rukhmanov, AA1
Dässler, CG1
Bjoro, K1
Dey, AC1
Abbott, EC1
Rusted, IE1
Senciall, IR1
Kriz, V1
Krizek, V1
Benes, K1
Adamírová, A1
Chrástek, J1
Staś, J1
Ri, H1
Oake, RJ1
Davies, SJ1
MacLachlan, MS1
Thomas, JP1
Saez, JM1
Morera, AM1
Dazord, A1
Bertrand, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00005138]0 participants Observational1976-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

14 reviews available for dehydroepiandrosterone and Hypertension

ArticleYear
Quo vadis basic and clinical chronobiology: promise for health maintenance.
    The American journal of anatomy, 1983, Volume: 168, Issue:4

    Topics: Adrenal Cortex; Alcoholism; Aldosterone; Biological Clocks; Blood Pressure; Breast Neoplasms; Cardio

1983
Hypertension of childhood with suppressed renin.
    Endocrine reviews, 1980,Fall, Volume: 1, Issue:4

    Topics: 18-Hydroxydesoxycorticosterone; 20-alpha-Dihydroprogesterone; Adolescent; Adrenal Cortex; Adrenal Hy

1980
Adrenal incidentaloma, a five year experience.
    Minerva endocrinologica, 1995, Volume: 20, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Aged; Algorithms; Carcinoma; C

1995
Management of mild pregnancy-induced hypertension remote from term.
    Seminars in perinatology, 1994, Volume: 18, Issue:2

    Topics: Adult; Ambulatory Care; Antihypertensive Agents; Bed Rest; Dehydroepiandrosterone; Dehydroepiandrost

1994
[Dehydroepiandrosterone, reticular area of adrenal cortex and resistance to stress and disease].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 1998, Issue:10

    Topics: Adjuvants, Immunologic; Animals; Arteriosclerosis; Dehydroepiandrosterone; Dehydroepiandrosterone Su

1998
Calorie restriction in primates: will it work and how will we know?
    Journal of the American Geriatrics Society, 1999, Volume: 47, Issue:7

    Topics: Aging; Analysis of Variance; Animals; Biomarkers; Body Weight; Cardiovascular Diseases; Cause of Dea

1999
New mineralocorticoids and adrenocorticosteroids in hypertension.
    The American journal of cardiology, 1976, Nov-23, Volume: 38, Issue:6

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Animals; Chemical Phenomena; Chemistry; Deh

1976
[Hyperuricemia and arteriosclerosis].
    Klinicheskaia meditsina, 1978, Volume: 56, Issue:1

    Topics: Adult; Arteriosclerosis; Coronary Disease; Dehydroepiandrosterone; Female; Gout; Humans; Hyperlipide

1978
Concurrent hypertension and pregnancy.
    Clinical obstetrics and gynecology, 1978, Volume: 21, Issue:3

    Topics: Amniotic Fluid; Antihypertensive Agents; Dehydroepiandrosterone; Diuretics; Estrogens; Female; Fetal

1978
Fetal considerations. Metabolic clearance rate of maternal plasma dehydroisoandrosterone sulfate.
    Seminars in perinatology, 1978, Volume: 2, Issue:1

    Topics: Benzothiadiazines; Dehydroepiandrosterone; Diuretics; Estradiol; Female; Humans; Hypertension; Mater

1978
[Deviation in steroid hormone secretion in essential hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1979, Jun-10, Volume: 37, Issue:6

    Topics: 18-Hydroxydesoxycorticosterone; Animals; Dehydroepiandrosterone; Desoxycorticosterone; Humans; Hyper

1979
[Mineralocorticoid excess in essential hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 1979, Volume: 37, Issue:10

    Topics: 18-Hydroxydesoxycorticosterone; Aldosterone; Animals; Dehydroepiandrosterone; Humans; Hydroxycortico

1979
The antenatal treatment of the fetus of the diabetic mother.
    Canadian Medical Association journal, 1971, Aug-07, Volume: 105, Issue:3

    Topics: Amniotic Fluid; Blood Glucose; Dehydroepiandrosterone; Delivery, Obstetric; Diet, Diabetic; Embryoni

1971
Assessment of adrenocortical function.
    The New England journal of medicine, 1971, Sep-23, Volume: 285, Issue:13

    Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenal Glands; Adrenal Insufficiency; Adult; Aldoster

1971

Trials

5 trials available for dehydroepiandrosterone and Hypertension

ArticleYear
Effects of the long-acting calcium channel blockers, amlodipine, manidipine and cilnidipine on steroid hormones and insulin resistance in hypertensive obese patients.
    Internal medicine (Tokyo, Japan), 2004, Volume: 43, Issue:7

    Topics: Aged; Amlodipine; Analysis of Variance; Body Mass Index; Calcium Channel Blockers; Dehydroepiandrost

2004
Effects of insulin reduction with benfluorex on serum dehydroepiandrosterone (DHEA), DHEA sulfate, and blood pressure in hypertensive middle-aged and elderly men.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:2

    Topics: Aged; Aging; Androgens; Blood Glucose; Blood Pressure; Dehydroepiandrosterone; Dehydroepiandrosteron

1995
Effects of nitrendipine on glucose tolerance and serum insulin and dehydroepiandrosterone sulfate levels in insulin-resistant obese and hypertensive men.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:1

    Topics: Adult; Analysis of Variance; Blood Glucose; Blood Pressure; Dehydroepiandrosterone; Dehydroepiandros

1993
The calcium channel blocker amlodipine raises serum dehydroepiandrosterone sulfate and androstenedione, but lowers serum cortisol, in insulin-resistant obese and hypertensive men.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:6

    Topics: Adult; Amlodipine; Androgens; Androstenedione; Calcium Channel Blockers; Dehydroepiandrosterone; Deh

1993
Dehydroepiandrosterone in the treatment of erectile dysfunction in patients with different organic etiologies.
    Urological research, 2001, Volume: 29, Issue:4

    Topics: Adult; Aged; Dehydroepiandrosterone; Diabetes Complications; Erectile Dysfunction; Humans; Hypertens

2001

Other Studies

70 other studies available for dehydroepiandrosterone and Hypertension

ArticleYear
Low serum dehydroepiandrosterone levels are associated with diabetic retinopathy in patients with type 2 diabetes mellitus.
    Journal of diabetes investigation, 2023, Volume: 14, Issue:5

    Topics: Cross-Sectional Studies; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Hu

2023
Hypoglycemia in Non-diabetics During Development of Acute Coronary Ischemia.
    Medical archives (Sarajevo, Bosnia and Herzegovina), 2015, Volume: 69, Issue:4

    Topics: Acute Disease; Age Factors; Ascorbic Acid; Cholecalciferol; Dehydroepiandrosterone; Female; Humans;

2015
Dehydroepiandrosterone-sulfate is associated with cardiovascular reactivity to stress in women.
    Psychoneuroendocrinology, 2016, Volume: 69

    Topics: Adult; Age Factors; Blood Flow Velocity; Blood Pressure; Cardiovascular Diseases; Cardiovascular Phy

2016
Dehydroepiandrosterone (DHEA) prevents the prostanoid imbalance in mesenteric bed of fructose-induced hypertensive rats.
    European journal of nutrition, 2008, Volume: 47, Issue:7

    Topics: Administration, Oral; Animals; Blood Pressure; Dehydroepiandrosterone; Disease Models, Animal; Fruct

2008
[Could serum DHEA and DHEAS levels be good risk predictors of metabolic syndrome and osteoporosis in the population of ageing men?].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2009, Volume: 27, Issue:159

    Topics: Adult; Aged; Aged, 80 and over; Aging; Comorbidity; Dehydroepiandrosterone; Dementia; Humans; Hypert

2009
Stimulation of Sigma-1 receptor by dehydroepiandrosterone ameliorates hypertension-induced kidney hypertrophy in ovariectomized rats.
    Experimental biology and medicine (Maywood, N.J.), 2010, Volume: 235, Issue:3

    Topics: Animals; Aorta, Abdominal; Aortic Valve Stenosis; Blood Pressure; Body Weight; Dehydroepiandrosteron

2010
Effects of cigarette smoking, metabolic syndrome and dehydroepiandrosterone deficiency on intima-media thickness and endothelial function in hypertensive postmenopausal women.
    Medical science monitor : international medical journal of experimental and clinical research, 2012, Volume: 18, Issue:4

    Topics: Anthropometry; Biomarkers; Blood Pressure; Carotid Intima-Media Thickness; Dehydroepiandrosterone; D

2012
Endogenous sex hormones, blood pressure change, and risk of hypertension in postmenopausal women: the Multi-Ethnic Study of Atherosclerosis.
    Atherosclerosis, 2012, Volume: 224, Issue:1

    Topics: Aged; Aged, 80 and over; Atherosclerosis; Blood Pressure; Dehydroepiandrosterone; Estradiol; Female;

2012
[EFFECT OF TREATMENT WITH NOR-ANDROSTENOLONE AND DECANOATE ON DIABETIC RETINOPATHY].
    Orvosi hetilap, 1964, Jun-21, Volume: 105

    Topics: Adolescent; Carbohydrate Metabolism; Decanoates; Dehydroepiandrosterone; Diabetes Mellitus, Type 1;

1964
[DEHYDROEPIANDROSTERONE DEFICIENCY IN THE URINE PATIENTS WITH HYPERTENSION].
    Casopis lekaru ceskych, 1964, Aug-14, Volume: 103

    Topics: Chromatography; Dehydroepiandrosterone; Fundus Oculi; Humans; Hypertension; Uric Acid; Urine

1964
HYPERURICAEMIA IN HYPERTENSION.
    Lancet (London, England), 1965, Mar-06, Volume: 1, Issue:7384

    Topics: Blood; Body Weight; Cholesterol; Creatine; Creatinine; Dehydroepiandrosterone; Fluids and Secretions

1965
The effect of hypertension in pregnant women on fetal adrenal function and fetal plasma lipoprotein-cholesterol metabolism.
    American journal of obstetrics and gynecology, 1984, Oct-01, Volume: 150, Issue:3

    Topics: Adrenal Glands; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Dehydroepiandros

1984
Two cases of low-renin hypertension thought to be due to excessive secretion of unknown mineralocorticoid.
    Japanese circulation journal, 1982, Volume: 46, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood P

1982
A study on dehydroepiandrosterone sulfate in patients with essential hypertension.
    Japanese circulation journal, 1982, Volume: 46, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Angiotensin II; Circadian Rhythm; Dehydroepiandrosterone; Dehydr

1982
Suppression of adrenal mineralocorticoid production in prehypertensive young adult men.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:1

    Topics: 18-Hydroxycorticosterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldosterone;

1983
Androgen modulation of adrenal angiotensin receptors.
    Science (New York, N.Y.), 1984, Jun-01, Volume: 224, Issue:4652

    Topics: Adrenal Cortex; Aldosterone; Androgens; Angiotensin II; Angiotensin III; Animals; Cattle; Cell Membr

1984
Inverse relation between low-density lipoprotein-cholesterol and dehydroisoandrosterone sulfate in human fetal plasma.
    Science (New York, N.Y.), 1980, May-02, Volume: 208, Issue:4443

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Cholesterol; Dehydroepiandrosterone; Dehydroepiandrosterone

1980
Serum 16 beta-hydroxydehydroepiandrosterone sulfate in man.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:5

    Topics: Adrenal Gland Diseases; Dehydroepiandrosterone; Female; Humans; Hypertension; Male; Radioimmunoassay

1980
[C-19 mineralocorticoids and hypertension of pregnancy].
    Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma, 1981, Volume: 52, Issue:1

    Topics: Adult; Amniotic Fluid; Androstenediols; Dehydroepiandrosterone; Female; Fetal Blood; Humans; Hyperte

1981
Disparate effects of insulin reduction with diltiazem on serum dehydroepiandrosterone sulfate levels in obese hypertensive men and women.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:4

    Topics: Adult; Blood Glucose; Blood Pressure; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Diltia

1994
Effects of a reduction in circulating insulin by metformin on serum dehydroepiandrosterone sulfate in nondiabetic men.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 78, Issue:3

    Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hypertension; Insulin; Lipids

1994
Influence of job strain and emotion on blood pressure in female hospital personnel during workhours.
    Scandinavian journal of work, environment & health, 1993, Volume: 19, Issue:5

    Topics: Adult; Arousal; Blood Pressure; Blood Pressure Monitors; Dehydroepiandrosterone; Emotions; Female; H

1993
Dehydroepiandrosterone does not prevent adrenocorticotrophin-induced hypertension in conscious rats.
    Clinical and experimental pharmacology & physiology, 1996, Volume: 23, Issue:5

    Topics: Adrenocorticotropic Hormone; Androgens; Animals; Consciousness; Dehydroepiandrosterone; Hypertension

1996
Childhood adrenocortical tumors.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:7

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Neoplasms; Age Factors; Child; Child, Preschool; Cushing

1997
Adult cardiovascular risk factors in premature babies.
    Lancet (London, England), 2000, Sep-09, Volume: 356, Issue:9233

    Topics: Adult; Birth Weight; Cardiovascular Diseases; Dehydroepiandrosterone; Female; Fetal Growth Retardati

2000
Effects of amlodipine on serum levels of adrenal androgens and insulin in hypertensive men with obesity.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2001, Volume: 33, Issue:3

    Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Dehydroepiandrosterone; Dehydroepiandrosterone Su

2001
Serum dehydroepiandrosterone sulfate and dehydroepiandrosterone levels in essential hypertension.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:1

    Topics: Adult; Age Factors; Dehydroepiandrosterone; Humans; Hydrocortisone; Hypertension; Male; Middle Aged

1975
Evidence for a new mineralocorticoid in patients with low-renin essential hypertension.
    Circulation research, 1975, Volume: 36, Issue:6 Suppl 1

    Topics: Adrenalectomy; Aldosterone; Animals; Biological Assay; Chromatography, Gas; Corticosterone; Cortison

1975
Assessment of placental function in normal and pathological pregnancies by estimation of plasma oestradiol levels after injection of dehydroepiandrosterone sulphate.
    British journal of obstetrics and gynaecology, 1975, Volume: 82, Issue:8

    Topics: Birth Weight; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Female; Fetal Death; Gestational

1975
New mineralcorticoids in the syndrome of low-renin essential hypertension.
    Journal of steroid biochemistry, 1975, Volume: 6, Issue:5

    Topics: Androstenediols; Biological Assay; Dehydroepiandrosterone; Humans; Hypertension; Mineralocorticoids;

1975
The metabolic clearance rate of dehydroisoandrosterone sulfate. IV. Acute effects of induced hypertension, hypotension, and naturesis in normal and hypertensive pregnancies.
    American journal of obstetrics and gynecology, 1976, Jan-15, Volume: 124, Issue:2

    Topics: Adult; Angiotensin II; Blood Pressure; Dehydroepiandrosterone; Female; Furosemide; Humans; Hydralazi

1976
Dehydroepiandrosterone sulfate loading test in the diagnosis of complicated pregnancies.
    The New England journal of medicine, 1976, Mar-04, Volume: 294, Issue:10

    Topics: Birth Weight; Dehydroepiandrosterone; Estradiol; Estriol; Female; Fetal Distress; Gestational Age; H

1976
Metabolic clearance rate of dehydroisoandrosterone sulfate. V. Studies of essential hypertension complicating pregnancy.
    Obstetrics and gynecology, 1976, Volume: 47, Issue:3

    Topics: Chronic Disease; Dehydroepiandrosterone; Female; Humans; Hydroxylation; Hypertension; Metabolic Clea

1976
Metabolic clearance rate of dehydroisoandrosterone sulfate. VI. Studies of eclampsia.
    Obstetrics and gynecology, 1976, Volume: 47, Issue:3

    Topics: Adult; Chronic Disease; Dehydroepiandrosterone; Eclampsia; Female; Follow-Up Studies; History of Med

1976
Increased prolactin levels during reserpine treatment of hypertensive patients.
    JAMA, 1976, May-24, Volume: 235, Issue:21

    Topics: Androstenedione; Dehydroepiandrosterone; Estradiol; Estrone; Female; Growth Hormone; Humans; Hyperte

1976
The Distinguished Lecture. Is hypertension essential?
    Transactions of the Association of American Physicians, 1975, Volume: 88

    Topics: Aldosterone; Aminoglutethimide; Angiotensin II; Animals; Dehydroepiandrosterone; Humans; Hypertensio

1975
Mineralocorticoid activity of 16beta-hydroxydehydroepiandrosterone and related steroids.
    The Journal of laboratory and clinical medicine, 1976, Volume: 88, Issue:4

    Topics: Animals; Biological Assay; Blood Pressure; Dehydroepiandrosterone; Hypertension; Male; Mineralocorti

1976
Dehydroepiandrosterone. Metabolic effects.
    Acta Universitatis Carolinae. Medica. Monographia, 1976, Volume: 71

    Topics: Adolescent; Adult; Androgens; Animals; Cell Division; Cell Membrane Permeability; Chemical Phenomena

1976
The clearance rate of maternal plasma prehormones of placental estrogen formation.
    Perspectives in nephrology and hypertension, 1976, Volume: 5

    Topics: Androstenedione; Dehydroepiandrosterone; Estradiol; Estrogens; Female; Humans; Hypertension; Metabol

1976
Interaction of 16beta-hydroxydehydroepiandrosterone with renal mineralocorticoid receptors.
    The Journal of laboratory and clinical medicine, 1977, Volume: 89, Issue:2

    Topics: Aldosterone; Animals; Binding, Competitive; Dehydroepiandrosterone; Hypertension; Kidney; Male; Mine

1977
[Plasma dehydroepiandrosterone and plasma dehydroepiandrosterone sulfate in various types of hypertension].
    Nihon Jinzo Gakkai shi, 1975, Volume: 17, Issue:1

    Topics: Adult; Dehydroepiandrosterone; Female; Humans; Hypertension; Male; Middle Aged

1975
Origin of urinary 16 beta-hydroxydehydroepiandrosterone in essential hypertension.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Dehydroepiandrosterone; Glucuronates; Humans; Hypertension; Renin; Sul

1977
Pathogenic significance of adrenocortical hormones in essential hypertension.
    Japanese circulation journal, 1977, Volume: 41, Issue:3

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Aldosterone; Cortodoxone; Dehydroepiandrost

1977
Differential diagnosis of hypertension in pregnancy.
    Clinics in obstetrics and gynaecology, 1977, Volume: 4, Issue:3

    Topics: Ambulatory Care; Angiotensin II; Blood Pressure; Chronic Disease; Dehydroepiandrosterone; Diagnosis,

1977
Effect of aminoglutethimide on blood pressure and steroid secretion in patients with low renin essential hypertension.
    The Journal of clinical investigation, 1978, Volume: 62, Issue:1

    Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Aminoglutethimide; Blood Pressure; Dehydroe

1978
Clinical application of estriol analysis.
    Clinical obstetrics and gynecology, 1978, Volume: 21, Issue:2

    Topics: Dehydroepiandrosterone; Diabetes Mellitus; Estriol; Female; Fetal Diseases; Fetal Growth Retardation

1978
Plasma dehydroepiandrosterone sulfate concentration in essential hypertension.
    Journal of steroid biochemistry, 1978, Volume: 9, Issue:7

    Topics: Adolescent; Adult; Age Factors; Aged; Black People; Dehydroepiandrosterone; Female; Humans; Hyperten

1978
Maternal plasma total oestriol and dehydroepiandrosterone sulfate loading test as indicators of feto-placental function or placental sulfatase deficiency.
    Journal of steroid biochemistry, 1979, Volume: 11, Issue:1B

    Topics: Birth Weight; Dehydroepiandrosterone; Estriol; Estrogens; Female; Fetus; Humans; Hypertension; Infan

1979
Plasma 16 beta-hydroxydehydroepiandrosterone in normal and pathological conditions in man.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 43, Issue:5

    Topics: Adolescent; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Child; Ch

1976
[Do aldosterone and other mineralocorticoids play a role in the pathogenesis of essential hypertension?].
    L'union medicale du Canada, 1977, Volume: 106, Issue:4

    Topics: 17-alpha-Hydroxypregnenolone; Adrenocorticotropic Hormone; Aldosterone; Animals; Blood Proteins; Cir

1977
Dehydroepiandrosterone prevents dexamethasone-induced hypertension in rats.
    The American journal of physiology, 1992, Volume: 263, Issue:2 Pt 1

    Topics: Animals; Blood Pressure; Dehydroepiandrosterone; Dexamethasone; Dose-Response Relationship, Drug; Hy

1992
Population study on the adipose tissue distribution in Japanese women born in 1948.
    Diabetes research and clinical practice, 1990, Volume: 10 Suppl 1

    Topics: Adipose Tissue; Adult; Androstenedione; Body Composition; Coronary Disease; Dehydroepiandrosterone;

1990
Sex steroid hormones are altered in essential hypertension.
    Journal of hypertension, 1989, Volume: 7, Issue:3

    Topics: Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; G

1989
Human salivary or plasma aldosterone- and dehydroepiandrosterone-binding glycoprotein induces hypertension in the rat.
    Clinical physiology and biochemistry, 1986, Volume: 4, Issue:6

    Topics: Animals; Blood Proteins; Carrier Proteins; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; H

1986
Dehydroepiandrosterone sulfate as a digitalis like factor in plasma of healthy human adults.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 49, Issue:3

    Topics: Adult; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate;

1985
Factors influencing urinary estrogen excretion in pregnancy.
    American journal of obstetrics and gynecology, 1967, Dec-01, Volume: 99, Issue:7

    Topics: Blood Chemical Analysis; Creatinine; Dehydroepiandrosterone; Estradiol; Estriol; Estrogens; Estrone;

1967
[On the clinico-physiologic characteristics of diencephalic disorders in cervical osteochondrosis].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1966, Volume: 66, Issue:10

    Topics: 17-Ketosteroids; Adult; Basal Metabolism; Blood Proteins; Brain Diseases; Cervical Vertebrae; Dehydr

1966
Further evidence of altered adrenocortical function in hypertension. Dehydroepiandrosterone excretion rate.
    Canadian journal of biochemistry, 1968, Volume: 46, Issue:9

    Topics: Adrenal Glands; Adult; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroep

1968
Secretion rate of dehydroepiandrosterone and dehydroepiandrosterone sulfate in benign essential hypertension as compared to normal subjects.
    Canadian journal of biochemistry, 1970, Volume: 48, Issue:12

    Topics: Adult; Carbon Isotopes; Chromatography; Chromatography, Thin Layer; Dehydroepiandrosterone; Female;

1970
Gas chromatographic analysis of estrogen and progesterone metabolites in human pregnancy urine.
    The American journal of medical technology, 1971, Volume: 37, Issue:7

    Topics: Birth Weight; Black People; Chemistry Techniques, Analytical; Chromatography, Gas; Dehydroepiandrost

1971
[Paroxysmal myoplegia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1971, Volume: 71, Issue:8

    Topics: Adult; Dehydroepiandrosterone; Electroencephalography; Goiter, Nodular; Humans; Hypertension; Male;

1971
[The functional state of the adrenal cortex and various aspects of the pathogenesis of cerebral circulatory disorders in hypertension and cerebral atherosclerosis].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Aged; Arteriosc

1972
Urinary excretion of dehydroepiandrosterone in normal and abnormal late pregnancy and in non-pregnant women.
    Acta endocrinologica, 1972, Volume: 71, Issue:1

    Topics: Adrenal Glands; Chromatography; Colorimetry; Dehydroepiandrosterone; Female; Fetal Death; Fetus; Hum

1972
[Oestrogen metabolism in pregnant women].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, Oct-20, Volume: 92, Issue:29

    Topics: Amniotic Fluid; Dehydroepiandrosterone; Estriol; Estrogens; Female; Fetal Death; Fetal Diseases; Fet

1972
Excretion of conjugated 11-deoxy-17-ketosteroids in "essential" hypertension.
    Canadian journal of biochemistry, 1972, Volume: 50, Issue:12

    Topics: 17-Ketosteroids; Adult; Age Factors; Aged; Aldosterone; Androstenes; Androsterone; Blood Pressure; C

1972
Some hormonal and metabolic effects of physical activity in hypertension.
    Endokrynologia Polska, 1974, Volume: 25, Issue:4

    Topics: Adult; Androsterone; Cholesterol; Dehydroepiandrosterone; Humans; Hypertension; Male; Middle Aged; P

1974
[Proceedings: Blood 11-deoxy-17-KS, dehydroepiandrosterone (DHEA) in dehydroepiandrosterone sulfate (DHEAS) in the field of internal medicine].
    Nihon Naibunpi Gakkai zasshi, 1974, Feb-20, Volume: 50, Issue:2

    Topics: 17-Ketosteroids; Adult; Dehydroepiandrosterone; Female; Humans; Hypertension; Male; Middle Aged; Neo

1974
Plasma testosterone in adrenal and ovarian vein blood of hirsute women.
    The Quarterly journal of medicine, 1974, Volume: 43, Issue:172

    Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Dehydroepiandrosterone; Dexamethasone; Female; Glucuronat

1974
Adrenal and testicular contribution to plasma oestrogens.
    The Journal of endocrinology, 1972, Volume: 55, Issue:1

    Topics: 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Androstanes; Breast Neopl

1972
The role of DHA in the pathogenesis of obesity and its metabolic complications.
    Polskie Archiwum Medycyny Wewnetrznej, 1969, Volume: 42, Issue:3

    Topics: Amino Acids; Arteriosclerosis; Cholesterol; Dehydroepiandrosterone; Diabetes Mellitus; Fatty Acids;

1969