Page last updated: 2024-08-24

clentiazem and Hypertension

clentiazem has been researched along with Hypertension in 12 studies

*Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. [MeSH]

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's9 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Das, J; Duff, KJ; Floyd, DM; Kimball, SD; Krapcho, J; Lago, MW; Lee, VG; Moquin, RV; Turk, CF; White, RE1
Das, J; Duff, KJ; Floyd, DM; Gougoutas, JZ; Kimball, SD; Lago, MW; Lee, VG; Malley, MF; Moquin, RV; Vu, TC1
Iwasaki, H; Kikkawa, K; Kurosawa, H; Murata, S; Nagao, T; Toriumi, W1
Barouki, F; el Fertak, L; Lévy, BI; Pieddeloup, C; Safar, ME1
Banno, K; Iwasaki, H; Kikkawa, K; Murata, S; Nagao, T; Toriumi, W1
Kusano, S; Mori, M; Suzuki, S1
Frohlich, ED; Ketelhut, R; McLoughlin, M1
Hirota, Y; Ishikawa, H; Ishikawa, K; Kagoshima, T; Katori, R; Kawakita, S; Kinoshita, M1
Raij, L; Tolins, JP1
Akimoto, Y; Kikkawa, K; Murata, S; Nagao, T; Narita, H; Sugawara, Y; Yabana, H1
Frohlich, ED; Isshiki, T; Pegram, BL2

Trials

2 trial(s) available for clentiazem and Hypertension

ArticleYear
Analysis of the daily variation in blood pressure and pharmacokinetics after single or repeated administration of clentiazem to patients with essential hypertension.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:4

    Topics: Aged; Blood Pressure; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diltiazem; Female; Heart; Humans; Hypertension; Male; Middle Aged; Pulse

1992
Efficacy and safety of clentiazem in patients with essential hypertension: results of an early pilot test.
    Clinical cardiology, 1991, Volume: 14, Issue:1

    Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Drug Administration Schedule; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Pilot Projects

1991

Other Studies

10 other study(ies) available for clentiazem and Hypertension

ArticleYear
Benzazepinone calcium channel blockers. 2. Structure-activity and drug metabolism studies leading to potent antihypertensive agents. Comparison with benzothiazepinones.
    Journal of medicinal chemistry, 1992, Feb-21, Volume: 35, Issue:4

    Topics: Acetylation; Animals; Antihypertensive Agents; Aorta; Benzazepines; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Hypertension; Male; Microsomes, Liver; Molecular Conformation; Molecular Structure; Pyrrolidines; Rabbits; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Vasodilation

1992
Benzazepinone calcium channel blockers. 3. Synthesis and structure-activity studies of 3-alkylbenzazepinones.
    Journal of medicinal chemistry, 1992, Feb-21, Volume: 35, Issue:4

    Topics: Animals; Antihypertensive Agents; Aorta; Benzazepines; Calcium Channel Blockers; Guinea Pigs; Hypertension; Male; Molecular Conformation; Molecular Structure; Muscles; Rabbits; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Vasodilation; X-Ray Diffraction

1992
Effect of clentiazem (TA-3090) with posttreatment on neurologic and histologic disorders of stroke-prone spontaneously hypertensive rats with history of stroke.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:1

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Brain; Cerebrovascular Disorders; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Kidney; Nervous System; Rats; Rats, Inbred SHR; Sodium, Dietary

1994
Role of endothelium in the mechanical response of the carotid arterial wall to calcium blockade in spontaneously hypertensive and Wistar-Kyoto rats.
    Journal of hypertension, 1993, Volume: 11, Issue:1

    Topics: Animals; Arteries; Calcium Channel Blockers; Carotid Arteries; Compliance; Diltiazem; Endothelium, Vascular; Hypertension; In Vitro Techniques; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1993
Prophylactic effects of a new 1,5-benzothiazepine calcium antagonist on stroke in salt-loaded stroke-prone spontaneously hypertensive rats.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:6

    Topics: Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Cerebral Cortex; Cerebrovascular Disorders; Circadian Rhythm; Diltiazem; Eating; Hypertension; Kidney Cortex; Male; Rats; Rats, Inbred SHR; Sodium Chloride

1992
Hemodynamic and metabolic effects of intravenous clentiazem in hypertensive patients.
    The American journal of cardiology, 1992, Jan-15, Volume: 69, Issue:3

    Topics: Aged; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Female; Hemodynamics; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Vascular Resistance

1992
Comparison of converting enzyme inhibitor and calcium channel blocker in hypertensive glomerular injury.
    Hypertension (Dallas, Tex. : 1979), 1990, Volume: 16, Issue:4

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Captopril; Diltiazem; Glomerular Filtration Rate; Hypertension; Kidney Failure, Chronic; Kidney Glomerulus; Male; Nephrectomy; Proteinuria; Rats; Rats, Inbred Strains; Thiazepines; Triglycerides

1990
Long-lasting hypotensive and antihypertensive effects of a new 1,5-benzothiazepine calcium antagonist in hypertensive rats and renal hypertensive dogs.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Diltiazem; Dogs; Electrocardiography; Electrolytes; Heart Rate; Hypertension; Hypertension, Renal; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Thiazepines

1988
Immediate and prolonged hemodynamic effects of TA-3090 on spontaneously hypertensive (SHR) and normal Wistar-Kyoto (WKY) rats.
    Cardiovascular drugs and therapy, 1988, Volume: 2, Issue:4

    Topics: Animals; Antihypertensive Agents; Diltiazem; Hemodynamics; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thiazepines

1988
Hemodynamic comparison of diltiazem and TA-3090 in spontaneously hypertensive and normal Wistar-Kyoto rats.
    The American journal of cardiology, 1988, Oct-05, Volume: 62, Issue:11

    Topics: Animals; Cerebrovascular Circulation; Coronary Circulation; Diltiazem; Hemodynamics; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Thiazepines; Vascular Resistance

1988