alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Hypertension in 6 studies
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypertension is a common and serious adverse effect of calcineurin inhibitors, including cyclosporine and tacrolimus (FK506)." | 4.12 | Calcineurin Controls Hypothalamic NMDA Receptor Activity and Sympathetic Outflow. ( Chen, SR; Pan, HL; Shao, JY; Zhou, JJ, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, G | 1 |
| Woods, C | 1 |
| Johnson, MA | 1 |
| Milner, TA | 1 |
| Glass, MJ | 1 |
| Zhou, JJ | 1 |
| Shao, JY | 1 |
| Chen, SR | 1 |
| Pan, HL | 1 |
| Lecrux, C | 1 |
| Nicole, O | 1 |
| Chazalviel, L | 1 |
| Catone, C | 1 |
| Chuquet, J | 1 |
| MacKenzie, ET | 1 |
| Touzani, O | 1 |
| Tsuchihashi, T | 1 |
| Abe, I | 1 |
| Fujishima, M | 1 |
| Maiorov, DN | 1 |
| Krenz, NR | 1 |
| Krassioukov, AV | 1 |
| Weaver, LC | 1 |
| Ashworth-Preece, MA | 1 |
| Chen, F | 1 |
| Jarrott, B | 1 |
| Lawrence, AJ | 1 |
6 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Hypertension
| Article | Year |
|---|---|
Angiotensin II Infusion Results in Both Hypertension and Increased AMPA GluA1 Signaling in Hypothalamic Paraventricular Nucleus of Male but not Female Mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Angiotensin II; Animals; Blood Pressure; F | 2022 |
Calcineurin Controls Hypothalamic NMDA Receptor Activity and Sympathetic Outflow.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Calcineurin; Calc | 2022 |
Spontaneously hypertensive rats are highly vulnerable to AMPA-induced brain lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Brain Damage, Chr | 2007 |
Role of metabotropic glutamate receptors in ventrolateral medulla of hypertensive rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Cycloleucine; Hea | 1994 |
Role of spinal NMDA and AMPA receptors in episodic hypertension in conscious spinal rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bloo | 1997 |
Visualisation of AMPA binding sites in the brain stem of normotensive and hypertensive rats.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain Ste | 1999 |