Page last updated: 2024-08-23

cicletanine and Hypertension

cicletanine has been researched along with Hypertension in 54 studies

*Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. [MeSH]

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199033 (61.11)18.7374
1990's16 (29.63)18.2507
2000's2 (3.70)29.6817
2010's3 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bassett, K; Jauca, CD; Musini, VM; Rezapour, P; Wright, JM1
Beals, C; Carey, RM; De Lepeleire, I; Fernandez, R; Gildea, J; Greenwalt, DM; Johnson-Levonas, AO; Malice, MP; McGrath, HE; Mitta, S; Nunes, I; Sisk, CM; Van Dyck, K; Wagner, F; Wiegert, E1
Sowers, JR; Whaley-Connell, A1
Agalakova, NI; Bagrov, AY; Droy-Lefaix, MT; Fedorova, OV; Lakatta, EG; Talan, MI1
Braquet, P; Chabrier, PE; Esanu, A1
Ando, K; Asano, S; Fujita, T; Ono, A; Sato, Y1
Bergamaschi, CT; Boim, MA; Bregman, R; Melhado, V; Moura, LA; Schor, N; Versolato, C1
Hirawa, N; Iwai, J; Kawabata, Y; Nagata, T; Numabe, A; Sugimoto, T; Takada, S; Uehara, Y1
Ando, K; Fujita, T; Ono, A; Sato, Y1
Imanishi, M; Kimura, G; Kuramochi, M; Matsuoka, H; Omae, T; Tsuji, T; Yasu, T1
Dité, C; Droy-Lefaix, MT; Gairard, A; Pernot, F; Van Overloop, B1
Akie, Y; Funahashi, N; Goto, A; Hirawa, N; Ichikawa, A; Kawabata, Y; Omata, M; Uehara, Y1
Imanishi, M; Yasu, T1
Kamimoto, M; Kanazawa, M; Kohzuki, M; Nagasaka, M; Saito, T; Sato, T; Wu, XM; Yasujima, M; Yoshida, K1
Adam, A; Bascands, JL; Berthet, P; Bompart, G; Emond, C; Girolami, JP; Pecher, C; Rakotoarivony, J; Tarrade, T1
Cabanie, M; Ebeigbe, AB1
Chen, YF; Durand, J; Esunge, P; Jin, HK; Oparil, S; Yang, RH1
Hirawa, N; Iwai, J; Kawabata, Y; Matsuoka, H; Numabe, A; Ono, H; Sugimoto, T; Takabatake, Y; Uehara, Y; Yagi, S1
Iwai, J; Kawabata, Y; Matsuoka, H; Nagata, T; Numabe, A; Sugimoto, T; Takabatake, Y; Uehara, Y; Yagi, S1
Bascands, JL; Berthet, P; Damase-Michel, C; Girolami, JP; Moatti, JP; Montastruc, JL; Pecher, C; Tarrade, T; Tran, MA1
MacGregor, GA; Markandu, ND; Singer, DR; Sugden, AL1
Curmi, P; Levy, BI; Poitevin, P; Safar, ME1
Bakri, F; Berthet, P; Bosquet, D; Droy-Lefaix, MT; Lhuintre, Y; Ruchoux, MM1
Berthet, P; Gavardin, T; Jungers, P; Salom, M; Tarrade, T1
Passa, P1
Aubert, I; Djian, F; Rouffy, J1
Berthet, P; Billaut, P; Carre, A; Clerson, P; Debeaumont, D; Deltour, L; Lefebvre, J; Tarrade, T1
Gryner, S; Witchitz, S1
Bakri, F; Berthet, P; Bosquet, D; Droy-Lefaix, MT; Guillemain, G; Narcisse, G; Ruchoux, MM1
Bakri, F; Bosquet, D; Droy, MT; Guillemain, J; Lhuintre, Y; Ruchoux, MM1
Betin, C; Braquet, P; Doly, M; Droy, MT; Malherbe, E; Millerin, M1
Chauveau, G; Droy, MT; Guillemain, J; Huguet, F; Lhuintre, Y; Ruchoux, MM1
Bakri, F; Berthet, P; Bosquet, D; Deby, C; Deby-Dupont, G; Droy-Lefaix, MT1
Castro, A; Fuentes, JA; Parra, L1
Berthet, P; Damase-Michel, C; Montastruc, JL; Tarrade, T; Tran, MA1
Boisson, J; Gaschard, JC; Hornych, A1
Allard, M; Berthet, P; Bosquet, D; Paillasseur, JL; Tarrade, T2
Fritel, D1
Cournot, P; Duchier, J; Safar, M1
Berthet, P; Billaut, P; Clerson, P; Deltour, L; Pauchant, M; Tarrade, T1
Deschamps de Paillette, E; Grimberg, D; Tarrade, T1
Braquet, P; Dagher, G; Deschamps de Paillette, E; Diez, J; Garay, R; Hannaert, P; Juin, G; Nazaret, C; Price, M1
Guinot, P; Jewitt-Harris, J; Tarrade, T1
Autret, A; Droy-Lefaix, MT; Gelot, A; Huguet, F; Ruchoux, MM; Ruchoux, P1
Alsasua, A; Castro, A; Fuentes, JA1
Braquet, P; Clostre, F; Le Hegarat, M; Malherbe, E1
Auguet, M; Baranes, J; Braquet, P; Clostre, F; Delaflotte, S; Le Hégarat, M; Malherbe, E1
Fodor, GP; Guinot, P1
Guinot, P; Tarrade, T1
Fredj, G1
Bouthier, JA; Deschamps, E; Safar, ME; Tarrade, T1
Auguet, M; Braquet, P; Clostre, F; Delaflotte, S; Guillon, JM; Le Hegarat, M; Pirotzky, E1
Castro, A; Florentino, A; Fuentes, JA1

Reviews

2 review(s) available for cicletanine and Hypertension

ArticleYear
Blood pressure-lowering efficacy of loop diuretics for primary hypertension.
    The Cochrane database of systematic reviews, 2015, May-22, Issue:5

    Topics: Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Furosemide; Humans; Hypertension; Indans; Pyridines; Randomized Controlled Trials as Topic; Sodium Potassium Chloride Symporter Inhibitors; Sulfonamides; Thiazoles

2015
Vascular remodeling and antihypertensive therapy: the example of cicletanine.
    Journal of cardiovascular pharmacology, 1993, Volume: 21 Suppl 1

    Topics: Animals; Antihypertensive Agents; Arteries; Hypertension; Pyridines; Rats; Rats, Inbred SHR; Vascular Resistance

1993

Trials

14 trial(s) available for cicletanine and Hypertension

ArticleYear
A comparison of the natriuretic and kaliuretic effects of cicletanine and hydrochlorothiazide in prehypertensive and hypertensive humans.
    Journal of hypertension, 2012, Volume: 30, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Double-Blind Method; G-Protein-Coupled Receptor Kinase 4; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Natriuresis; Polymorphism, Single Nucleotide; Potassium; Prehypertension; Pyridines

2012
Effects of cicletanine on prostaglandin I2 and E2 levels in patients with essential hypertension.
    American journal of hypertension, 1997, Volume: 10, Issue:7 Pt 1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Antihypertensive Agents; Blood Pressure; Dinoprostone; Double-Blind Method; Epoprostenol; Female; Humans; Hypertension; Male; Middle Aged; Pyridines; Sodium

1997
A comparison of the acute effects of cicletanine and bendrofluazide on urinary electrolytes and plasma potassium in essential hypertension.
    European journal of clinical pharmacology, 1990, Volume: 39, Issue:3

    Topics: Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Creatinine; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Pulse; Pyridines; Random Allocation; Sodium

1990
[Comparative study of 2 dosages of a new antihypertensive agent, cicletanine, in elderly subjects].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Male; Multicenter Studies as Topic; Prospective Studies; Pyridines; Random Allocation

1989
[Cicletanine tolerance in hypertensive patients with metabolic disorders].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Antihypertensive Agents; Diuretics; Double-Blind Method; Drug Evaluation; Female; Humans; Hypertension; Indapamide; Male; Metabolic Diseases; Pyridines; Randomized Controlled Trials as Topic

1989
[Antihypertensive effectiveness and tolerance of cicletanine. Results obtained with monotherapy in a large population].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Evaluation; Female; France; Humans; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Pyridines

1989
[Dose-effectiveness relationship of cicletanine at short-term in moderately to severely hypertensive patients].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged; Pyridines; Randomized Controlled Trials as Topic

1989
[Evaluation of the effectiveness of a cicletanine-enalapril combination in hypertensive patients].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Evaluation; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Pyridines; Randomized Controlled Trials as Topic

1989
[Evaluation of cicletanine efficiency and tolerance in hypertensive patients treated with beta-blockaders].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Pyridines; Random Allocation

1989
[Antihypertensive effectiveness and tolerance of cicletanine. Results obtained with bitherapy].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Pyridines

1989
[Cicletanine administered with other antihypertensive agents].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Nifedipine; Pyridines

1989
Determination of the optimal dose of the antihypertensive drug cicletanine hydrochloride in man.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Pyridines; Random Allocation; Sodium; Time Factors

1989
Review of three studies to determine the efficacy and tolerance of cicletanine in the short- and long-term treatment of essential hypertension.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:2-3

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Pyridines

1988
Efficacy and tolerance of cicletanine, a new antihypertensive agent: overview of 1226 treated patients.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:2-3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Tolerance; Humans; Hypertension; Middle Aged; Muscle, Smooth, Vascular; Pyridines; Random Allocation

1988

Other Studies

38 other study(ies) available for cicletanine and Hypertension

ArticleYear
The kaliuretic impact of cicletanine compared to hydrochlorothiazide.
    Journal of hypertension, 2012, Volume: 30, Issue:4

    Topics: Antihypertensive Agents; Humans; Hydrochlorothiazide; Hypertension; Male; Natriuresis; Potassium; Prehypertension; Pyridines

2012
Myocardial PKC beta2 and the sensitivity of Na/K-ATPase to marinobufagenin are reduced by cicletanine in Dahl hypertension.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:3

    Topics: Animals; Antihypertensive Agents; Binding Sites; Blood Pressure; Bufanolides; Enzyme Inhibitors; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Kidney; Protein Kinase C; Protein Kinase C beta; Pyridines; Rats; Rats, Inbred Dahl; Sarcolemma; Sodium-Potassium-Exchanging ATPase

2003
Involvement of the sympathetic nervous system in antihypertensive effect of cicletanine in salt-loaded young spontaneously hypertensive rats.
    American journal of hypertension, 1994, Volume: 7, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Dopamine; Hexamethonium; Hypertension; Male; Norepinephrine; Pyridines; Random Allocation; Rats; Rats, Inbred SHR; Sodium, Dietary; Sympathetic Nervous System

1994
Effect of cicletanine on the progression of chronic renal failure in rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1993, Volume: 26, Issue:1

    Topics: Animals; Glomerulosclerosis, Focal Segmental; Hypertension; Hypertension, Renal; Kidney Failure, Chronic; Kidney Glomerulus; Proteinuria; Pyridines; Rats; Rats, Wistar; Time Factors

1993
Possible radical scavenging properties of cicletanine and renal protection in Dahl salt sensitive rats.
    American journal of hypertension, 1993, Volume: 6, Issue:6 Pt 1

    Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Brain; Epoprostenol; Free Radical Scavengers; Hypertension; Kidney; Leukotrienes; Lipid Peroxidation; Lipid Peroxides; Pyridines; Rats; Rats, Inbred Strains; Sodium, Dietary; Xanthine; Xanthine Oxidase; Xanthines

1993
Involvement of prostaglandins and renal haemodynamics in salt-sensitivity of young spontaneously hypertensive rats.
    Journal of hypertension, 1993, Volume: 11, Issue:4

    Topics: Animals; Blood Pressure; Dinoprostone; Hypertension; Indomethacin; Male; Prostaglandins; Pyridines; Rats; Rats, Inbred SHR; Renal Circulation; Sodium Chloride; Vascular Resistance

1993
Short-term increase in prostaglandin I2 synthesis caused by cicletanine in patients with essential hypertension.
    American journal of hypertension, 1995, Volume: 8, Issue:9

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Antihypertensive Agents; Dinoprostone; Epoprostenol; Female; Humans; Hypertension; Male; Middle Aged; Pyridines; Renin

1995
[Chronic and acute effect of cycletanine in NO-dependent hypertensive pregnant rats].
    Archives des maladies du coeur et des vaisseaux, 1995, Volume: 88, Issue:8

    Topics: Animals; Antihypertensive Agents; Arginine; Blood Pressure; Dinoprost; Enzyme Inhibitors; Female; Hypertension; Nitric Oxide; Nitroarginine; Oxytocics; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy, Animal; Prostaglandins F; Proteinuria; Pyridines; Rats; Rats, Wistar; Vasoconstriction

1995
Restoration of endothelial cell function by chronic cicletanine treatment in Dahl salt-sensitive rats with salt-induced hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1996, Volume: 19, Issue:4

    Topics: Animals; Antihypertensive Agents; Aorta; Body Weight; Diet, Sodium-Restricted; Dinoprostone; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Hemodynamics; Hypertension; Kidney; Microscopy, Electron, Scanning; Nitric Oxide; Organ Culture Techniques; Pyridines; Rats; Rats, Inbred Strains; Sodium Chloride; Vasodilator Agents

1996
Renal-protective effect of nondepressor dose of cicletanine in diabetic rats with hypertension.
    American journal of hypertension, 2000, Volume: 13, Issue:3

    Topics: Albuminuria; Analysis of Variance; Animals; Antihypertensive Agents; Blood Glucose; Blood Urea Nitrogen; Body Weight; Creatinine; Diabetes Mellitus, Experimental; Diastole; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Kidney; Kidney Glomerulus; Necrosis; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole; Time Factors

2000
Protective effect of cicletanine on hypertension-induced decreases in the renal kallikrein-kinin and prostaglandin systems in stroke-prone spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Amino Acid Sequence; Animals; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Dinoprostone; Hypertension; Kallikrein-Kinin System; Kallikreins; Kidney; Kinins; Male; Molecular Sequence Data; Phospholipases A; Prostaglandins; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1992
Responses of isolated human epigastric arteries to histamine.
    Journal of the autonomic nervous system, 1992, Volume: 39, Issue:3

    Topics: Abdominal Muscles; Arteries; Diuretics; Endothelium; Female; Histamine; Histamine Antagonists; Humans; Hypertension; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Pregnancy; Pyridines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2

1992
Antihypertensive effect of cicletanine is exaggerated in NaCl-sensitive hypertension.
    The American journal of the medical sciences, 1991, Volume: 301, Issue:6

    Topics: Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Diuretics; Epinephrine; Heart Rate; Hypertension; Male; Pyridines; Rats; Rats, Inbred SHR; Sodium Chloride; Sodium, Dietary

1991
Antihypertensive effects of cicletanine and renal protection in Dahl salt-sensitive rats.
    Journal of hypertension, 1991, Volume: 9, Issue:8

    Topics: Animals; Antihypertensive Agents; Dinoprostone; Diuretics; Eicosanoids; Epoprostenol; Glomerular Filtration Rate; Hypertension; Kidney; Myocardium; Organ Size; Pyridines; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride; Thromboxane A2

1991
Evidence for medial-mass regression in the vascular wall of Dahl hypertensive rats by cicletanine treatment.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Aorta; Cells, Cultured; Diuretics; Electrophoresis, Polyacrylamide Gel; Hypertension; In Vitro Techniques; Indicators and Reagents; Muscle, Smooth, Vascular; Myosins; Protein Biosynthesis; Pyridines; Rats; Rats, Inbred Strains; Renal Artery; Sodium Chloride

1991
Effects of cicletanine on vasoactive systems in conscious sinoaortic-denervated dogs.
    Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:8

    Topics: Aldosterone; Amino Acid Sequence; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Catecholamines; Creatinine; Diuretics; Dogs; Female; Heart Rate; Hypertension; Kallikreins; Male; Molecular Sequence Data; Potassium; Prostaglandins; Pyridines; Renin; Sodium; Urea

1991
Modifications of the arterial mechanical properties of normotensive and hypertensive rats without arterial pressure changes.
    Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Arteries; Blood Pressure; Carotid Arteries; Diuretics; Hemodynamics; Hypertension; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors

1989
[Protective action of cicletanine on the vascular walls in stroke-prone spontaneously hypertensive rats].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82, Issue:7

    Topics: Animals; Arteries; Arterioles; Diuretics; Endothelium, Vascular; Hypertension; Pyridines; Rats; Rats, Inbred SHR; Vascular Diseases

1989
[Effects of cicletanine on plasma lipid metabolism. Mid-term open trial in hypertensive patients with normal blood lipids and hyperlipidemia].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Adult; Aged; Diuretics; Humans; Hyperlipidemias; Hypertension; Lipid Metabolism; Male; Middle Aged; Pyridines; Time Factors

1989
[Changes in the glucose tolerance parameters in non-diabetic hypertensive patients treated with cicletanine].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Adult; Aged; Antihypertensive Agents; Blood Glucose; Diuretics; Female; Glucose Tolerance Test; Humans; Hypertension; Male; Middle Aged; Pyridines

1989
[Evaluation of rhythm tolerance of cicletanine using continuous electrocardiographic recording].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Adult; Aged; Antihypertensive Agents; Arrhythmias, Cardiac; Diuretics; Drug Evaluation; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Pyridines

1989
[Effectiveness of cicletanine on lesions in spontaneously hypertensive rats. Curative study--dose-effect relationship].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Animals; Brain Diseases; Cardiomyopathies; Diuretics; Dose-Response Relationship, Drug; Hypertension; Kidney Diseases; Male; Organ Size; Pyridines; Rats; Rats, Inbred SHR

1989
[Comparison of the effects of cicletanine and captopril on kidney and heart lesions in spontaneously hypertensive rats (SHR-SP)].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Animals; Captopril; Cardiomyopathies; Diuretics; Hypertension; Kidney Diseases; Male; Pyridines; Rats; Rats, Inbred SHR

1989
[Protective effect of cicletanine in hypertensive retinopathy. Evaluation of retinal function in the isolated retina].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Animals; Diuretics; Electroretinography; Hypertension; Pyridines; Rats; Rats, Inbred SHR; Retinal Diseases

1989
[Effects of cicletanine on kidney lesions associated with age. Light and electron microscopy studies].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Aging; Animals; Chronic Disease; Diuretics; Glomerulonephritis; Hypertension; Kidney Diseases; Microscopy, Electron; Pyridines; Rats; Rats, Inbred Strains

1989
[Effects of treatment with cicletanine on kidney PGE2 and PGI1 in spontaneously hypertensive rats].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Animals; Diuretics; Dose-Response Relationship, Drug; Epoprostenol; Hypertension; Kidney; Male; Prostaglandins E; Pyridines; Rats; Rats, Inbred SHR

1989
Studies on the mechanism of action of the antihypertensive agent cicletanine.
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Diuretics; Hypertension; Male; Muscle, Smooth, Vascular; Norepinephrine; Pyridines; Rats; Rats, Inbred Strains

1989
[Cicletanine and the sympathetic nervous system. A study of awake sino-aortic denervated hypertensive dogs].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Animals; Antihypertensive Agents; Catecholamines; Diuretics; Dogs; Double-Blind Method; Female; Hypertension; Male; Pyridines; Random Allocation; Sympathectomy; Sympathetic Nervous System

1989
[Reduction of kidney prostaglandin synthesis in patients with essential hypertension. Stimulating effect of cicletanine].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82 Spec No 4

    Topics: Adult; Aged; Antihypertensive Agents; Diuretics; Epoprostenol; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Prostaglandins E; Pyridines

1989
A classification of essential hypertensive patients according to the erythrocyte Na transport abnormalities: an application for monitoring the antihypertensive response to cicletanide.
    Klinische Wochenschrift, 1985, Volume: 63 Suppl 3

    Topics: Adult; Aged; Antihypertensive Agents; Biological Transport; Diuretics; Erythrocytes; Female; Humans; Hypertension; Ion Channels; Lithium; Male; Middle Aged; Potassium; Pyridines; Sodium

1985
The effect of cicletanine on cerebrovascular injury in stroke-prone spontaneously hypertensive rats.
    American journal of hypertension, 1989, Volume: 2, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Behavior, Animal; Brain; Cerebrovascular Disorders; Diuretics; Hypertension; Male; Meninges; Pyridines; Rats; Rats, Inbred Strains

1989
The effect of acute and subchronic treatment with cicletanine on DOCA-salt hypertension in the rat.
    American journal of hypertension, 1989, Volume: 2, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Desoxycorticosterone; Diuretics; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Pyridines; Rats; Rats, Inbred Strains

1989
Comparison of cicletanine with other antihypertensive drugs in SHR-SP models.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:2-3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Diuresis; Diuretics; Electrolytes; Hydrochlorothiazide; Hypertension; Hypertrophy; Indapamide; Kidney; Male; Prazosin; Pyridines; Rats; Rats, Inbred SHR

1988
Antihypertensive profile of cicletanine, a furopyridine derivative: comparison with captopril, indapamide and prazosin.
    Pharmacological research communications, 1988, Volume: 20 Suppl 3

    Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Cardiomegaly; Diuresis; Diuretics; Hypertension; In Vitro Techniques; Indapamide; Male; Prazosin; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vasoconstriction

1988
Clinical pharmacokinetics of cicletanine hydrochloride.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:2-3

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Biological Availability; Diuretics; Female; Half-Life; Humans; Hypertension; Kidney Failure, Chronic; Liver Diseases; Male; Middle Aged; Protein Binding; Pyridines

1988
Haemodynamic effects of an antihypertensive diuretic substance on the forearm circulation of patients with essential hypertension.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:2-3

    Topics: Adult; Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Brachial Artery; Diuretics; Female; Forearm; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Pyridines; Time Factors; Vascular Resistance

1988
In vivo and in vitro effects of cicletanine in spontaneously hypertensive rats.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:2-3

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Calcium; Diuretics; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Pyridines; Rats; Rats, Inbred SHR

1988
Antihypertensive effect of non-diuretic doses of cicletanine on a stress-induced model in the rat.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:2-3

    Topics: Animals; Antihypertensive Agents; Diuretics; Hypertension; Male; Pyridines; Rats; Rats, Inbred Strains; Stress, Physiological

1988