cicletanine has been researched along with Hypertension in 54 studies
*Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. [MeSH]
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 33 (61.11) | 18.7374 |
1990's | 16 (29.63) | 18.2507 |
2000's | 2 (3.70) | 29.6817 |
2010's | 3 (5.56) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Bassett, K; Jauca, CD; Musini, VM; Rezapour, P; Wright, JM | 1 |
Beals, C; Carey, RM; De Lepeleire, I; Fernandez, R; Gildea, J; Greenwalt, DM; Johnson-Levonas, AO; Malice, MP; McGrath, HE; Mitta, S; Nunes, I; Sisk, CM; Van Dyck, K; Wagner, F; Wiegert, E | 1 |
Sowers, JR; Whaley-Connell, A | 1 |
Agalakova, NI; Bagrov, AY; Droy-Lefaix, MT; Fedorova, OV; Lakatta, EG; Talan, MI | 1 |
Braquet, P; Chabrier, PE; Esanu, A | 1 |
Ando, K; Asano, S; Fujita, T; Ono, A; Sato, Y | 1 |
Bergamaschi, CT; Boim, MA; Bregman, R; Melhado, V; Moura, LA; Schor, N; Versolato, C | 1 |
Hirawa, N; Iwai, J; Kawabata, Y; Nagata, T; Numabe, A; Sugimoto, T; Takada, S; Uehara, Y | 1 |
Ando, K; Fujita, T; Ono, A; Sato, Y | 1 |
Imanishi, M; Kimura, G; Kuramochi, M; Matsuoka, H; Omae, T; Tsuji, T; Yasu, T | 1 |
Dité, C; Droy-Lefaix, MT; Gairard, A; Pernot, F; Van Overloop, B | 1 |
Akie, Y; Funahashi, N; Goto, A; Hirawa, N; Ichikawa, A; Kawabata, Y; Omata, M; Uehara, Y | 1 |
Imanishi, M; Yasu, T | 1 |
Kamimoto, M; Kanazawa, M; Kohzuki, M; Nagasaka, M; Saito, T; Sato, T; Wu, XM; Yasujima, M; Yoshida, K | 1 |
Adam, A; Bascands, JL; Berthet, P; Bompart, G; Emond, C; Girolami, JP; Pecher, C; Rakotoarivony, J; Tarrade, T | 1 |
Cabanie, M; Ebeigbe, AB | 1 |
Chen, YF; Durand, J; Esunge, P; Jin, HK; Oparil, S; Yang, RH | 1 |
Hirawa, N; Iwai, J; Kawabata, Y; Matsuoka, H; Numabe, A; Ono, H; Sugimoto, T; Takabatake, Y; Uehara, Y; Yagi, S | 1 |
Iwai, J; Kawabata, Y; Matsuoka, H; Nagata, T; Numabe, A; Sugimoto, T; Takabatake, Y; Uehara, Y; Yagi, S | 1 |
Bascands, JL; Berthet, P; Damase-Michel, C; Girolami, JP; Moatti, JP; Montastruc, JL; Pecher, C; Tarrade, T; Tran, MA | 1 |
MacGregor, GA; Markandu, ND; Singer, DR; Sugden, AL | 1 |
Curmi, P; Levy, BI; Poitevin, P; Safar, ME | 1 |
Bakri, F; Berthet, P; Bosquet, D; Droy-Lefaix, MT; Lhuintre, Y; Ruchoux, MM | 1 |
Berthet, P; Gavardin, T; Jungers, P; Salom, M; Tarrade, T | 1 |
Passa, P | 1 |
Aubert, I; Djian, F; Rouffy, J | 1 |
Berthet, P; Billaut, P; Carre, A; Clerson, P; Debeaumont, D; Deltour, L; Lefebvre, J; Tarrade, T | 1 |
Gryner, S; Witchitz, S | 1 |
Bakri, F; Berthet, P; Bosquet, D; Droy-Lefaix, MT; Guillemain, G; Narcisse, G; Ruchoux, MM | 1 |
Bakri, F; Bosquet, D; Droy, MT; Guillemain, J; Lhuintre, Y; Ruchoux, MM | 1 |
Betin, C; Braquet, P; Doly, M; Droy, MT; Malherbe, E; Millerin, M | 1 |
Chauveau, G; Droy, MT; Guillemain, J; Huguet, F; Lhuintre, Y; Ruchoux, MM | 1 |
Bakri, F; Berthet, P; Bosquet, D; Deby, C; Deby-Dupont, G; Droy-Lefaix, MT | 1 |
Castro, A; Fuentes, JA; Parra, L | 1 |
Berthet, P; Damase-Michel, C; Montastruc, JL; Tarrade, T; Tran, MA | 1 |
Boisson, J; Gaschard, JC; Hornych, A | 1 |
Allard, M; Berthet, P; Bosquet, D; Paillasseur, JL; Tarrade, T | 2 |
Fritel, D | 1 |
Cournot, P; Duchier, J; Safar, M | 1 |
Berthet, P; Billaut, P; Clerson, P; Deltour, L; Pauchant, M; Tarrade, T | 1 |
Deschamps de Paillette, E; Grimberg, D; Tarrade, T | 1 |
Braquet, P; Dagher, G; Deschamps de Paillette, E; Diez, J; Garay, R; Hannaert, P; Juin, G; Nazaret, C; Price, M | 1 |
Guinot, P; Jewitt-Harris, J; Tarrade, T | 1 |
Autret, A; Droy-Lefaix, MT; Gelot, A; Huguet, F; Ruchoux, MM; Ruchoux, P | 1 |
Alsasua, A; Castro, A; Fuentes, JA | 1 |
Braquet, P; Clostre, F; Le Hegarat, M; Malherbe, E | 1 |
Auguet, M; Baranes, J; Braquet, P; Clostre, F; Delaflotte, S; Le Hégarat, M; Malherbe, E | 1 |
Fodor, GP; Guinot, P | 1 |
Guinot, P; Tarrade, T | 1 |
Fredj, G | 1 |
Bouthier, JA; Deschamps, E; Safar, ME; Tarrade, T | 1 |
Auguet, M; Braquet, P; Clostre, F; Delaflotte, S; Guillon, JM; Le Hegarat, M; Pirotzky, E | 1 |
Castro, A; Florentino, A; Fuentes, JA | 1 |
2 review(s) available for cicletanine and Hypertension
Article | Year |
---|---|
Blood pressure-lowering efficacy of loop diuretics for primary hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Furosemide; Humans; Hypertension; Indans; Pyridines; Randomized Controlled Trials as Topic; Sodium Potassium Chloride Symporter Inhibitors; Sulfonamides; Thiazoles | 2015 |
Vascular remodeling and antihypertensive therapy: the example of cicletanine.
Topics: Animals; Antihypertensive Agents; Arteries; Hypertension; Pyridines; Rats; Rats, Inbred SHR; Vascular Resistance | 1993 |
14 trial(s) available for cicletanine and Hypertension
Article | Year |
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A comparison of the natriuretic and kaliuretic effects of cicletanine and hydrochlorothiazide in prehypertensive and hypertensive humans.
Topics: Adult; Aged; Antihypertensive Agents; Double-Blind Method; G-Protein-Coupled Receptor Kinase 4; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Natriuresis; Polymorphism, Single Nucleotide; Potassium; Prehypertension; Pyridines | 2012 |
Effects of cicletanine on prostaglandin I2 and E2 levels in patients with essential hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Antihypertensive Agents; Blood Pressure; Dinoprostone; Double-Blind Method; Epoprostenol; Female; Humans; Hypertension; Male; Middle Aged; Pyridines; Sodium | 1997 |
A comparison of the acute effects of cicletanine and bendrofluazide on urinary electrolytes and plasma potassium in essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Creatinine; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Pulse; Pyridines; Random Allocation; Sodium | 1990 |
[Comparative study of 2 dosages of a new antihypertensive agent, cicletanine, in elderly subjects].
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Male; Multicenter Studies as Topic; Prospective Studies; Pyridines; Random Allocation | 1989 |
[Cicletanine tolerance in hypertensive patients with metabolic disorders].
Topics: Antihypertensive Agents; Diuretics; Double-Blind Method; Drug Evaluation; Female; Humans; Hypertension; Indapamide; Male; Metabolic Diseases; Pyridines; Randomized Controlled Trials as Topic | 1989 |
[Antihypertensive effectiveness and tolerance of cicletanine. Results obtained with monotherapy in a large population].
Topics: Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Evaluation; Female; France; Humans; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Pyridines | 1989 |
[Dose-effectiveness relationship of cicletanine at short-term in moderately to severely hypertensive patients].
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged; Pyridines; Randomized Controlled Trials as Topic | 1989 |
[Evaluation of the effectiveness of a cicletanine-enalapril combination in hypertensive patients].
Topics: Aged; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Evaluation; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Pyridines; Randomized Controlled Trials as Topic | 1989 |
[Evaluation of cicletanine efficiency and tolerance in hypertensive patients treated with beta-blockaders].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Pyridines; Random Allocation | 1989 |
[Antihypertensive effectiveness and tolerance of cicletanine. Results obtained with bitherapy].
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Pyridines | 1989 |
[Cicletanine administered with other antihypertensive agents].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Nifedipine; Pyridines | 1989 |
Determination of the optimal dose of the antihypertensive drug cicletanine hydrochloride in man.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Pyridines; Random Allocation; Sodium; Time Factors | 1989 |
Review of three studies to determine the efficacy and tolerance of cicletanine in the short- and long-term treatment of essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Pyridines | 1988 |
Efficacy and tolerance of cicletanine, a new antihypertensive agent: overview of 1226 treated patients.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Tolerance; Humans; Hypertension; Middle Aged; Muscle, Smooth, Vascular; Pyridines; Random Allocation | 1988 |
38 other study(ies) available for cicletanine and Hypertension
Article | Year |
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The kaliuretic impact of cicletanine compared to hydrochlorothiazide.
Topics: Antihypertensive Agents; Humans; Hydrochlorothiazide; Hypertension; Male; Natriuresis; Potassium; Prehypertension; Pyridines | 2012 |
Myocardial PKC beta2 and the sensitivity of Na/K-ATPase to marinobufagenin are reduced by cicletanine in Dahl hypertension.
Topics: Animals; Antihypertensive Agents; Binding Sites; Blood Pressure; Bufanolides; Enzyme Inhibitors; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Kidney; Protein Kinase C; Protein Kinase C beta; Pyridines; Rats; Rats, Inbred Dahl; Sarcolemma; Sodium-Potassium-Exchanging ATPase | 2003 |
Involvement of the sympathetic nervous system in antihypertensive effect of cicletanine in salt-loaded young spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dopamine; Hexamethonium; Hypertension; Male; Norepinephrine; Pyridines; Random Allocation; Rats; Rats, Inbred SHR; Sodium, Dietary; Sympathetic Nervous System | 1994 |
Effect of cicletanine on the progression of chronic renal failure in rats.
Topics: Animals; Glomerulosclerosis, Focal Segmental; Hypertension; Hypertension, Renal; Kidney Failure, Chronic; Kidney Glomerulus; Proteinuria; Pyridines; Rats; Rats, Wistar; Time Factors | 1993 |
Possible radical scavenging properties of cicletanine and renal protection in Dahl salt sensitive rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Brain; Epoprostenol; Free Radical Scavengers; Hypertension; Kidney; Leukotrienes; Lipid Peroxidation; Lipid Peroxides; Pyridines; Rats; Rats, Inbred Strains; Sodium, Dietary; Xanthine; Xanthine Oxidase; Xanthines | 1993 |
Involvement of prostaglandins and renal haemodynamics in salt-sensitivity of young spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Dinoprostone; Hypertension; Indomethacin; Male; Prostaglandins; Pyridines; Rats; Rats, Inbred SHR; Renal Circulation; Sodium Chloride; Vascular Resistance | 1993 |
Short-term increase in prostaglandin I2 synthesis caused by cicletanine in patients with essential hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Antihypertensive Agents; Dinoprostone; Epoprostenol; Female; Humans; Hypertension; Male; Middle Aged; Pyridines; Renin | 1995 |
[Chronic and acute effect of cycletanine in NO-dependent hypertensive pregnant rats].
Topics: Animals; Antihypertensive Agents; Arginine; Blood Pressure; Dinoprost; Enzyme Inhibitors; Female; Hypertension; Nitric Oxide; Nitroarginine; Oxytocics; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy, Animal; Prostaglandins F; Proteinuria; Pyridines; Rats; Rats, Wistar; Vasoconstriction | 1995 |
Restoration of endothelial cell function by chronic cicletanine treatment in Dahl salt-sensitive rats with salt-induced hypertension.
Topics: Animals; Antihypertensive Agents; Aorta; Body Weight; Diet, Sodium-Restricted; Dinoprostone; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Hemodynamics; Hypertension; Kidney; Microscopy, Electron, Scanning; Nitric Oxide; Organ Culture Techniques; Pyridines; Rats; Rats, Inbred Strains; Sodium Chloride; Vasodilator Agents | 1996 |
Renal-protective effect of nondepressor dose of cicletanine in diabetic rats with hypertension.
Topics: Albuminuria; Analysis of Variance; Animals; Antihypertensive Agents; Blood Glucose; Blood Urea Nitrogen; Body Weight; Creatinine; Diabetes Mellitus, Experimental; Diastole; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Kidney; Kidney Glomerulus; Necrosis; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole; Time Factors | 2000 |
Protective effect of cicletanine on hypertension-induced decreases in the renal kallikrein-kinin and prostaglandin systems in stroke-prone spontaneously hypertensive rats.
Topics: 6-Ketoprostaglandin F1 alpha; Amino Acid Sequence; Animals; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Dinoprostone; Hypertension; Kallikrein-Kinin System; Kallikreins; Kidney; Kinins; Male; Molecular Sequence Data; Phospholipases A; Prostaglandins; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1992 |
Responses of isolated human epigastric arteries to histamine.
Topics: Abdominal Muscles; Arteries; Diuretics; Endothelium; Female; Histamine; Histamine Antagonists; Humans; Hypertension; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Pregnancy; Pyridines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1992 |
Antihypertensive effect of cicletanine is exaggerated in NaCl-sensitive hypertension.
Topics: Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Diuretics; Epinephrine; Heart Rate; Hypertension; Male; Pyridines; Rats; Rats, Inbred SHR; Sodium Chloride; Sodium, Dietary | 1991 |
Antihypertensive effects of cicletanine and renal protection in Dahl salt-sensitive rats.
Topics: Animals; Antihypertensive Agents; Dinoprostone; Diuretics; Eicosanoids; Epoprostenol; Glomerular Filtration Rate; Hypertension; Kidney; Myocardium; Organ Size; Pyridines; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride; Thromboxane A2 | 1991 |
Evidence for medial-mass regression in the vascular wall of Dahl hypertensive rats by cicletanine treatment.
Topics: Animals; Anti-Arrhythmia Agents; Aorta; Cells, Cultured; Diuretics; Electrophoresis, Polyacrylamide Gel; Hypertension; In Vitro Techniques; Indicators and Reagents; Muscle, Smooth, Vascular; Myosins; Protein Biosynthesis; Pyridines; Rats; Rats, Inbred Strains; Renal Artery; Sodium Chloride | 1991 |
Effects of cicletanine on vasoactive systems in conscious sinoaortic-denervated dogs.
Topics: Aldosterone; Amino Acid Sequence; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Catecholamines; Creatinine; Diuretics; Dogs; Female; Heart Rate; Hypertension; Kallikreins; Male; Molecular Sequence Data; Potassium; Prostaglandins; Pyridines; Renin; Sodium; Urea | 1991 |
Modifications of the arterial mechanical properties of normotensive and hypertensive rats without arterial pressure changes.
Topics: Animals; Anti-Arrhythmia Agents; Arteries; Blood Pressure; Carotid Arteries; Diuretics; Hemodynamics; Hypertension; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors | 1989 |
[Protective action of cicletanine on the vascular walls in stroke-prone spontaneously hypertensive rats].
Topics: Animals; Arteries; Arterioles; Diuretics; Endothelium, Vascular; Hypertension; Pyridines; Rats; Rats, Inbred SHR; Vascular Diseases | 1989 |
[Effects of cicletanine on plasma lipid metabolism. Mid-term open trial in hypertensive patients with normal blood lipids and hyperlipidemia].
Topics: Adult; Aged; Diuretics; Humans; Hyperlipidemias; Hypertension; Lipid Metabolism; Male; Middle Aged; Pyridines; Time Factors | 1989 |
[Changes in the glucose tolerance parameters in non-diabetic hypertensive patients treated with cicletanine].
Topics: Adult; Aged; Antihypertensive Agents; Blood Glucose; Diuretics; Female; Glucose Tolerance Test; Humans; Hypertension; Male; Middle Aged; Pyridines | 1989 |
[Evaluation of rhythm tolerance of cicletanine using continuous electrocardiographic recording].
Topics: Adult; Aged; Antihypertensive Agents; Arrhythmias, Cardiac; Diuretics; Drug Evaluation; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Pyridines | 1989 |
[Effectiveness of cicletanine on lesions in spontaneously hypertensive rats. Curative study--dose-effect relationship].
Topics: Animals; Brain Diseases; Cardiomyopathies; Diuretics; Dose-Response Relationship, Drug; Hypertension; Kidney Diseases; Male; Organ Size; Pyridines; Rats; Rats, Inbred SHR | 1989 |
[Comparison of the effects of cicletanine and captopril on kidney and heart lesions in spontaneously hypertensive rats (SHR-SP)].
Topics: Animals; Captopril; Cardiomyopathies; Diuretics; Hypertension; Kidney Diseases; Male; Pyridines; Rats; Rats, Inbred SHR | 1989 |
[Protective effect of cicletanine in hypertensive retinopathy. Evaluation of retinal function in the isolated retina].
Topics: Animals; Diuretics; Electroretinography; Hypertension; Pyridines; Rats; Rats, Inbred SHR; Retinal Diseases | 1989 |
[Effects of cicletanine on kidney lesions associated with age. Light and electron microscopy studies].
Topics: Aging; Animals; Chronic Disease; Diuretics; Glomerulonephritis; Hypertension; Kidney Diseases; Microscopy, Electron; Pyridines; Rats; Rats, Inbred Strains | 1989 |
[Effects of treatment with cicletanine on kidney PGE2 and PGI1 in spontaneously hypertensive rats].
Topics: Animals; Diuretics; Dose-Response Relationship, Drug; Epoprostenol; Hypertension; Kidney; Male; Prostaglandins E; Pyridines; Rats; Rats, Inbred SHR | 1989 |
Studies on the mechanism of action of the antihypertensive agent cicletanine.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Diuretics; Hypertension; Male; Muscle, Smooth, Vascular; Norepinephrine; Pyridines; Rats; Rats, Inbred Strains | 1989 |
[Cicletanine and the sympathetic nervous system. A study of awake sino-aortic denervated hypertensive dogs].
Topics: Animals; Antihypertensive Agents; Catecholamines; Diuretics; Dogs; Double-Blind Method; Female; Hypertension; Male; Pyridines; Random Allocation; Sympathectomy; Sympathetic Nervous System | 1989 |
[Reduction of kidney prostaglandin synthesis in patients with essential hypertension. Stimulating effect of cicletanine].
Topics: Adult; Aged; Antihypertensive Agents; Diuretics; Epoprostenol; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Prostaglandins E; Pyridines | 1989 |
A classification of essential hypertensive patients according to the erythrocyte Na transport abnormalities: an application for monitoring the antihypertensive response to cicletanide.
Topics: Adult; Aged; Antihypertensive Agents; Biological Transport; Diuretics; Erythrocytes; Female; Humans; Hypertension; Ion Channels; Lithium; Male; Middle Aged; Potassium; Pyridines; Sodium | 1985 |
The effect of cicletanine on cerebrovascular injury in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Anti-Arrhythmia Agents; Behavior, Animal; Brain; Cerebrovascular Disorders; Diuretics; Hypertension; Male; Meninges; Pyridines; Rats; Rats, Inbred Strains | 1989 |
The effect of acute and subchronic treatment with cicletanine on DOCA-salt hypertension in the rat.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Desoxycorticosterone; Diuretics; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Pyridines; Rats; Rats, Inbred Strains | 1989 |
Comparison of cicletanine with other antihypertensive drugs in SHR-SP models.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Diuresis; Diuretics; Electrolytes; Hydrochlorothiazide; Hypertension; Hypertrophy; Indapamide; Kidney; Male; Prazosin; Pyridines; Rats; Rats, Inbred SHR | 1988 |
Antihypertensive profile of cicletanine, a furopyridine derivative: comparison with captopril, indapamide and prazosin.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Captopril; Cardiomegaly; Diuresis; Diuretics; Hypertension; In Vitro Techniques; Indapamide; Male; Prazosin; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vasoconstriction | 1988 |
Clinical pharmacokinetics of cicletanine hydrochloride.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Biological Availability; Diuretics; Female; Half-Life; Humans; Hypertension; Kidney Failure, Chronic; Liver Diseases; Male; Middle Aged; Protein Binding; Pyridines | 1988 |
Haemodynamic effects of an antihypertensive diuretic substance on the forearm circulation of patients with essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Brachial Artery; Diuretics; Female; Forearm; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Pyridines; Time Factors; Vascular Resistance | 1988 |
In vivo and in vitro effects of cicletanine in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Calcium; Diuretics; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Pyridines; Rats; Rats, Inbred SHR | 1988 |
Antihypertensive effect of non-diuretic doses of cicletanine on a stress-induced model in the rat.
Topics: Animals; Antihypertensive Agents; Diuretics; Hypertension; Male; Pyridines; Rats; Rats, Inbred Strains; Stress, Physiological | 1988 |