Page last updated: 2024-08-23

substance p and Hypertension

substance p has been researched along with Hypertension in 119 studies

Research

Studies (119)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (31.09)	18.7374
1990's	36 (30.25)	18.2507
2000's	32 (26.89)	29.6817
2010's	13 (10.92)	24.3611
2020's	1 (0.84)	2.80

Authors

Authors	Studies
Briggs, I; Dutta, AS; Gormley, JJ; Graham, AS; Growcott, JW; Jamieson, A	1
Ahn, D; Bills, KB; Chang, S; Fan, Y; Gwak, YS; Kim, DH; Kim, HY; Lee, BH; Ryu, Y; Steffensen, SC; Yang, CH	1
Chowdhury, YS; Kostis, JB; Kostis, WJ; Shetty, M	1
Chen, P; E, XQ; Fan, Y; Feng, Y; Guo, YX; He, C; Li, BY; Liu, S; Ma, MN; Qiao, GF; Wang, LQ; Wang, TY; Wang, Y; Yuan, M	1
Dehlin, HM; Levick, SP; Manteufel, EJ; Monroe, AL; Reimer, MH	1
Gildea, JJ; Howell, NL; Kemp, BA; Padia, SH	1
Armando, I; Jose, PA	1
Gao, F; Garavito, RM; Sui, D; Wang, DH; Worden, RM	1
Andersson, KE; Imamura, T; Ishizuka, O; Kurizaki, Y; Nakayama, T; Nishizawa, O; Ogawa, T; Tanabe, T; Zhong, C	1
Brower, GL; Janicki, JS; Levick, SP; Murray, DB	1
Bonham, AC; Chen, CY	1
Couture, R; De Brito Gariepy, H	1
Hayashida, Y; Kusakabe, T; Matsuda, H; Takahashi, M; Tsukuda, M; Yamamoto, Y	1
Byrd, JS; Elsayed, R; Marshall, GD; Minor, DS	1
Carlström, M; Hrafnkelsdóttir, TJ; Jern, S; Ridderstråle, W; Saluveer, O	1
Imamura, T; Ishikawa, M; Ishizuka, O; Kurizaki, Y; Nishizawa, O; Noguchi, W; Zhang, L	1
de Carvalho, JJ; Felix, AS; Nascimento, AL; Rocha, VN	1
Wang, DH; Wang, Y	1
Dipette, DJ; Katki, KA; Supowit, SC; Watson, RE; Zhao, H	1
Bakhle, YS; Bell, C; Brady, F	1
Cicha, MZ; Kopp, UC	1
Sudakov, KV	1
Chang, Q; Ding, J; Gong, S	1
Boscan, P; Dutschmann, M; Herbert, H; Paton, JF	1
Ding, J; Gong, S	1
Wang, DH	1
DiPette, D; Fink, GD; Galligan, JJ; Katki, K; Miller, SB; Supowit, S	1
Brouillette, J; Cloutier, F; Couture, R; Deschamps, K; Neugebauer, W; Ongali, B	1
Hrafnkelsdóttir, T; Jern, S; Ridderstråle, W; Ulfhammer, E	1
Brown, DR; Cameron, AA; Rabchevsky, AG; Randall, DC; Smith, GM	1
Cicha, MZ; Kopp, UC; Smith, LA	1
Ku, YH	1
Buclin, T; Grouzmann, E	1
Adam, A; Brown, NJ; Byrd, JB; Gainer, JV; Nadeau, J; Sile, S; Touzin, K; Yu, C	1
Hayashi, T; Nakamura, K	1
Agnati, L; Fuxe, K; Ganten, D; Hökfelt, T; Rascher, W; Unger, T	1
Ganten, D; Rettig, R; Rockhold, RW; Unger, T; Yukimura, T	1
Campbell, WB; Gomez-Sanchez, CE; Graham, RM; Holland, OB; Pettinger, WA; White, AC	1
Brody, MJ; Gebhart, GF; Knuepfer, MM; McManus, DQ; Virus, RM	1
Hecht, K; Hilse, H; Moritz, V; Oehme, P; Poppei, M; Scheer, E; Thu, M	1
Bienert, M; Marten, FT; Oehme, P; Richter, R	1
Gebhart, GF; McManus, DQ; Virus, RM	2
Hecht, K; Oehme, P; Poppei, M	2
Hecht, K; Oehme, P; Poppei, M; Roske, I	1
Mouri, T; Murakami, O; Yoshinaga, K	1
Hilse, H; Oehme, P; Rathsack, R; Roske, I	2
Oehme, P; Roske, I	1
Faulhaber, HD; Görne, RC; Hartrodt, W; Homuth, V; Naumann, E; Oehme, P; Pfeiffer, D; Rathsack, R; Rostock, G	1
Hecht, K; Hilse, H; Oehme, P; Rathsack, R; Roske, I	1
Regoli, D	1
Cezaretti, ML; Gavras, H; Gavras, I; Ginoza, M; Kohlmann, O; Leeman, SE; Ramos, OL; Ribeiro, AB; Tavares, A; Zanella, MT	1
Cao, SP; Zhao, LY	1
Asakura, S; Mori, K; Ogawa, H; Sasagawa, S; Takeyama, M	1
Archer, SL; Hampl, V; Isaacson, TC; Nelson, DP; Weir, EK	1
Casino, PR; Kilcoyne, CM; Panza, JA; Quyyumi, AA	1
Egashira, K; Hirooka, Y; Imaizumi, T; Kai, H; Sugimachi, M; Suzuki, S; Takeshita, A	1
Burg, M; Knuepfer, MM; Zahm, DS	1
Ling, EA; Tan, CK; Tang, FR	1
Ebihara, A; Fujimura, A; Shiga, T; Sunaga, K	1
Chadwick, IG; Jackson, PR; Kraskiewicz, M; Ramsay, LE; Yeo, WW	1
Hirayama, Y; Ichinose, M; Kageyama, N; Miura, M; Shirato, K; Tomaki, M; Yamauchi, H	1
Bucinskaite, V; Crumpton, K; Ekblom, A; Lundeberg, T; Stenfors, C; Theodorsson, E	1
Condorelli, G; Ganten, D; Ganten, U; Iaccarino, G; Lindpaintner, K; Rizzoni, D; Rubattu, S; Russo, R; Trimarco, B; Vecchione, C; Volpe, M	1
Andrews, NP; Cannon, RO; Husain, S; Mulcahy, D; Panza, JA; Quyyumi, AA	1
Cesaretti, ML; Gavras, H; Gavras, I; Ginoza, M; Kohlmann, O; Leeman, SE; Ramos, OL; Ribeiro, AB; Tavares, A; Zanella, MT	1
Gauthier-Rein, KM; Rusch, NJ	1
Cicha, MZ; Dixon, BS; Farley, DM; Kopp, UC; Smith, LA	1
Ding, X; Ku, YH; Li, LS; Tan, L	1
Arai, T; Fujiwara, H; Kashiki, Y; Takaya, T; Toshima, S; Yasuda, Y; Yoshimi, N	2
Arnolda, LF; Chalmers, JP; Llewellyn-Smith, IJ; Minson, JB; Pilowsky, PM; Solomon, SG	1
Bakhle, YS; Bell, C; Brogan, JD	1
Arai, T; Fujiwara, H; Kashiki, Y; Takaya, T; Toshima, S; Yasuda, Y; Yoshimii, N	1
Bakhle, YS; Beddy, P; Bell, C; Campbell, VA; Foley, A	1
Albright, GM; Hosaka, M; Janz, R; Li, JL; Richardson, JA; Shelton, JM; Südhof, TC; Victor, RG; Zhang, W	1
Hancock, JC; Hoover, DB; Schoborg, RV; Tompkins, JD	1
Arai, T; Fujiwara, H; Kashiki, Y; Shibayama, M; Takaya, T; Toshima, S; Yasuda, Y; Yoshimi, N	1
Echizen, H; Fukatsu, T; Hashiguchi, M; Itoh, T; Kariya, S; Nishimura, E; Odanaka, J; Ohtani, M; Okumura, H; Rikihisa, T; Takahashi, T; Uchino, K; Watanabe, K	1
Deng, Z; Gao, M; Yan, C	1
DiPette, DJ; Katki, KA; Supowit, SC	2
Edvinsson, L; Lind, H	1
Ku, YH; Li, YH	1
Germanson, TP; Guyenet, PG; Wang, H	1
Hancock, JC; Tompkins, JD	1
Cannon, D; Kirrane, J; Legge, D; Powell, D; Skrabanek, P	1
Edvinsson, L; Ekman, R; Erlinge, D; Thulin, T	1
Criscuoli, M; Giachetti, A; Guelfi, M; Sardelli, G; Subissi, A	1
Unger, T	1
Kawamura, K; Takebayashi, S	1
Colditz, M; Faulhaber, HD; Gurk, C; Martin, G; Stechmesser, G; Urmantcheeva, TG; Wolter, F	1
Butovskaia, ML; Deriagina, MA; Startsev, VG	1
Chen, J; Gao, J; Liu, Y; Xu, C; Xue, H	1
Masuyama, Y; Tsuda, K	1
Chen, J	1
Katsumata, U; Sasaki, H; Sekizawa, K; Takishima, T; Ujiie, Y	1
Carson, J; DiPette, DJ; Holland, OB; Westlund, KN	1
Bell, C; Messina, A	1
Nieber, K; Oehme, P; Roske, I	1
Li, XQ; Li, XW; Zhu, CX	1
Henriksen, JH; Kastrup, J; Schaffalitzky De Muckadell, OB	1
Charlton, CG; Helke, CJ; Keeler, JR	1
Castren, E; Kurihara, M; Niwa, M; Saavedra, JM; Shigematsu, K	1
Ariano, MA; Kenny, SL	1
Daniel, EE; Lee, RM; McKenzie, R; Nagahama, M	1
Faulhaber, HD; Hecht, K; Nieber, K; Oehme, P; Rathsack, R; Roske, I	1
Baumann, R; Enderlein, J; Faulhaber, HD; Naumann, E; Oehme, P; Rathsack, R; Rostock, G	1
Gabrysiak, B; Minenko, A; Oehme, P	1
Andersson, KE; Andersson, SI; Ekman, R; Thysell, H	1
Brattström, A; Nitschkoff, S; Oehme, P; Starzev, VG; Stechmesser, G	1
Kimura, K; Masuyama, Y; Nishio, I; Shima, H; Takeda, J; Tsuda, K; Ura, M	1
Bell, C; Gurusinghe, CJ	2
Edvinsson, L; Ekman, R; Thulin, T	2
Govoni, S; Izumi, F; Kobayashi, H; Magnoni, MS; Trabucchi, M; Wada, A	1

Reviews

11 review(s) available for substance p and Hypertension

Article	Year
ACE Inhibitor-Induced Angioedema: a Review. Current hypertension reports, 2018, 06-08, Volume: 20, Issue:7 Topics: Adrenal Cortex Hormones; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Capillary Permeability; Combined Modality Therapy; Epinephrine; Female; Histamine Antagonists; Humans; Hypertension; Intubation, Intratracheal; Risk Factors; Substance P; Vasodilation	2018
Postexercise hypotension: central mechanisms. Exercise and sport sciences reviews, 2010, Volume: 38, Issue:3 Topics: Animals; Baroreflex; Blood Pressure; Brain Stem; Exercise; gamma-Aminobutyric Acid; Humans; Hypertension; Hypotension; Neuronal Plasticity; Rats; Substance P; Sympathetic Nervous System	2010
Role of sensory nervous system vasoactive peptides in hypertension. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2002, Volume: 35, Issue:9 Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Cells, Cultured; Desoxycorticosterone; Disease Models, Animal; Female; Hypertension; Mice; Mice, Knockout; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Pregnancy; Rats; Rats, Inbred SHR; Sensory Receptor Cells; Substance P	2002
The vanilloid receptor and hypertension. Acta pharmacologica Sinica, 2005, Volume: 26, Issue:3 Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Humans; Hypertension; Ion Channels; Neurons, Afferent; Receptors, Drug; Renin-Angiotensin System; Sodium Chloride, Dietary; Substance P; TRPV Cation Channels	2005
Role of limbic peptidergic circuits in regulation of arterial pressure, relevant to development of essential hypertension. Neuropeptides, 2006, Volume: 40, Issue:5 Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; beta-Endorphin; Blood Pressure; Corticotropin-Releasing Hormone; Humans; Hypertension; Limbic System; Neuropeptides; Substance P	2006
Peptidergic and catecholaminergic mechanisms in central blood pressure control. Contributions to nephrology, 1980, Volume: 23 Topics: Angiotensin II; Animals; Blood Pressure; Brain; Catecholamines; Disease Models, Animal; Epinephrine; Humans; Hypertension; Kinins; Neurotransmitter Agents; Norepinephrine; Peptides; Pressoreceptors; Rats; Substance P	1980
[Blood pressure regulation and shock]. Nihon rinsho. Japanese journal of clinical medicine, 1983, Volume: 41, Issue:5 Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Endorphins; Hypertension; Nerve Tissue Proteins; Neurotensin; Rats; Rats, Inbred Strains; Shock; Substance P; Vasopressins	1983
[Polypeptides and antagonists]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1984, Mar-29, Volume: 60, Issue:14 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Humans; Hypertension; Inflammation; Kallikreins; Kinins; Neurotensin; Peptides; Renin-Angiotensin System; Substance P; Vasoactive Intestinal Peptide	1984
Bulbospinal substance P and sympathetic regulation of the cardiovascular system: a review. Peptides, 1985, Volume: 6 Suppl 2 Topics: Animals; Autonomic Fibers, Preganglionic; Bicuculline; Brain Mapping; Cardiovascular Physiological Phenomena; Cats; Efferent Pathways; gamma-Aminobutyric Acid; Hypertension; Injections, Spinal; Medulla Oblongata; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred SHR; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Spinal Cord; Substance P; Sympathetic Nervous System; Synaptic Transmission	1985
Relationship of substance P to catecholamines, stress, and hypertension. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 12 Topics: Adrenal Glands; Animals; Blood Pressure; Catecholamines; Heart Rate; Hypertension; In Vitro Techniques; Models, Biological; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Stress, Physiological; Substance P	1987
Neuronal control of brain microvessel function. Experientia, 1985, Apr-15, Volume: 41, Issue:4 Topics: Acetylcholine; Aging; Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; Capillaries; Capillary Permeability; Cerebrovascular Circulation; Cholecystokinin; Diabetes Mellitus; Dopamine; Endothelium; Histamine; Hypertension; Hypoxia, Brain; Locus Coeruleus; Microcirculation; Neural Pathways; Neurons; Norepinephrine; Receptors, Neurotransmitter; Serotonin; Substance P; Vasoactive Intestinal Peptide	1985

Trials

7 trial(s) available for substance p and Hypertension

Article	Year
Impaired capacity for stimulated fibrinolysis in primary hypertension is restored by antihypertensive therapy. Hypertension (Dallas, Tex. : 1979), 2006, Volume: 47, Issue:4 Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Brachial Artery; Calcium Channel Blockers; Felodipine; Female; Fibrinolysis; Forearm; Hemodynamics; Humans; Hypertension; Injections, Intra-Arterial; Lisinopril; Male; Middle Aged; Regional Blood Flow; Substance P; Tissue Plasminogen Activator; Vascular Resistance; Vasodilation	2006
Chronopharmacology of enalapril in hypertensive patients. European journal of clinical pharmacology, 1995, Volume: 48, Issue:6 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Cough; Dinoprostone; Enalapril; Enalaprilat; Female; Half-Life; Humans; Hypertension; Male; Middle Aged; Substance P	1995
Resolution of ACE inhibitor cough: changes in subjective cough and responses to inhaled capsaicin, intradermal bradykinin and substance-P. British journal of clinical pharmacology, 1995, Volume: 40, Issue:5 Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Capsaicin; Cough; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Substance P	1995
Angiotensin-converting enzyme inhibitors, angiotensin II receptor antagonists, and symptomless dysphagia. Chest, 2000, Volume: 117, Issue:6 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Deglutition Disorders; Female; Humans; Hypertension; Imidazoles; Imidazolidines; Losartan; Male; Pneumonia, Aspiration; Stroke; Substance P	2000
Angiotensin II receptor antagonists cannot prevent symptomless dysphagia in hypertensive bedridden older patients with stroke. Journal of the American Geriatrics Society, 2000, Volume: 48, Issue:12 Topics: Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Antihypertensive Agents; Bed Rest; Case-Control Studies; Deglutition Disorders; Female; Humans; Hypertension; Losartan; Male; Stroke; Substance P; Treatment Outcome	2000
Enhanced vasodilator responses to calcitonin gene-related peptide (CGRP) in subcutaneous arteries in human hypertension. Journal of human hypertension, 2002, Volume: 16, Issue:1 Topics: Aged; Arteries; Calcitonin Gene-Related Peptide; Female; Humans; Hypertension; Male; Middle Aged; Muscle, Smooth; Neuromuscular Depolarizing Agents; Norepinephrine; Potassium; Skin; Substance P; Vasoconstrictor Agents; Vasodilation; Vasomotor System; Veins	2002
Bradykinin-induced cough reflex markedly increases in patients with cough associated with captopril and enalapril. The Tohoku journal of experimental medicine, 1991, Volume: 164, Issue:2 Topics: Adult; Aerosols; Aged; Bradykinin; Captopril; Citrates; Citric Acid; Cough; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Reflex; Respiratory Function Tests; Substance P	1991

Other Studies

101 other study(ies) available for substance p and Hypertension

Article	Year
Analogues of substance P. Peptides containing D-amino acid residues in various positions of substance P and displaying agonist or receptor selective antagonist effects. Journal of medicinal chemistry, 1986, Volume: 29, Issue:7 Topics: Amino Acid Sequence; Amino Acids; Animals; Blood Pressure; Guinea Pigs; Hypertension; In Vitro Techniques; Indicators and Reagents; Muscle Contraction; Muscle, Smooth; Rabbits; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Stereoisomerism; Structure-Activity Relationship; Substance P	1986
The role of substance P in acupuncture signal transduction and effects. Brain, behavior, and immunity, 2021, Volume: 91 Topics: Acupuncture Points; Acupuncture Therapy; Animals; Hypertension; Rats; Signal Transduction; Substance P	2021
Direct activation of tachykinin receptors within baroreflex afferent pathway and neurocontrol of blood pressure regulation. CNS neuroscience & therapeutics, 2019, Volume: 25, Issue:1 Topics: Afferent Pathways; Animals; Baroreflex; Blood Pressure; Estrogens; Female; Hypertension; Male; Nodose Ganglion; Pressoreceptors; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Tachykinin; Solitary Nucleus; Substance P	2019
Substance P acting via the neurokinin-1 receptor regulates adverse myocardial remodeling in a rat model of hypertension. International journal of cardiology, 2013, Oct-12, Volume: 168, Issue:5 Topics: Animals; Disease Models, Animal; Female; Gene Expression Regulation, Developmental; Heart Ventricles; Hypertension; Myocytes, Cardiac; Polymerase Chain Reaction; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Ventricular Function, Left; Ventricular Remodeling	2013
Intrarenal ghrelin receptor antagonism prevents high-fat diet-induced hypertension in male rats. Endocrinology, 2014, Volume: 155, Issue:7 Topics: Animals; Blotting, Western; Body Weight; Diet, High-Fat; Eating; Ghrelin; Hypertension; Kidney; Male; Nephrectomy; Oligopeptides; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Receptors, Ghrelin; Sodium; Substance P; Time Factors	2014
Sensing salt intake. Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:2 Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Hypertension; Rats; Rats, Inbred Dahl; Salt Tolerance; Sodium Chloride, Dietary; Substance P; TRPV Cation Channels	2009
Salt intake augments hypotensive effects of transient receptor potential vanilloid 4: functional significance and implication. Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:2 Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Ganglia, Spinal; Hypertension; Hypotension; Kidney; Male; Mesenteric Arteries; Phorbol Esters; Rats; Rats, Wistar; Ruthenium Red; Salt Tolerance; Sodium Chloride, Dietary; Substance P; TRPV Cation Channels	2009
An extract (THC-002) of Ba-Wei-Die-Huang-Wan inhibits expression of tachykinins, and P2X3 and TRPV1 receptors, and inhibits ATP-induced detrusor overactivity in spontaneously hypertensive rats. Neurourology and urodynamics, 2009, Volume: 28, Issue:6 Topics: Adenosine Triphosphate; Administration, Oral; Animals; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Female; Hypertension; Immunohistochemistry; Neurokinin A; Neurokinin B; Rats; Rats, Inbred SHR; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Tachykinins; TRPV Cation Channels; Urinary Bladder; Urinary Bladder, Overactive; Urination	2009
Sympathetic nervous system modulation of inflammation and remodeling in the hypertensive heart. Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:2 Topics: Analysis of Variance; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hypertension; Inflammation Mediators; Male; Myocytes, Cardiac; Probability; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance P; Sympathectomy; Sympathetic Nervous System; Ventricular Remodeling	2010
Blockade of tachykinin NK3 receptor reverses hypertension through a dopaminergic mechanism in the ventral tegmental area of spontaneously hypertensive rats. British journal of pharmacology, 2010, Volume: 161, Issue:8 Topics: Animals; Benzazepines; Blood Pressure; Dopamine; Haloperidol; Heart Rate; Hypertension; Ibotenic Acid; Indoles; Male; Oligopeptides; Peptide Fragments; Quinolines; Raclopride; Rats; Rats, Inbred SHR; Receptors, Neurokinin-3; Substance P; Ventral Tegmental Area	2010
Morphological characteristics and peptidergic innervation in the carotid body of spontaneously hypertensive rats. Histology and histopathology, 2011, Volume: 26, Issue:3 Topics: Animals; Calcitonin Gene-Related Peptide; Carotid Body; Coloring Agents; Eosine Yellowish-(YS); Hematoxylin; Hypertension; Immunohistochemistry; Male; Nerve Fibers; Neuropeptide Y; Neuropeptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Species Specificity; Substance P; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide	2011
DPP-4 inhibitors and angioedema: a cause for concern? Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2011, Volume: 106, Issue:5 Topics: Angioedema; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypertension; Product Surveillance, Postmarketing; Substance P	2011
The impaired fibrinolytic capacity in hypertension is unaffected by acute blood pressure lowering. Journal of thrombosis and thrombolysis, 2011, Volume: 32, Issue:4 Topics: Antihypertensive Agents; Blood Pressure; Endothelium, Vascular; Fibrinolysis; Humans; Hypertension; Middle Aged; Nitroprusside; Substance P; Tissue Plasminogen Activator; Vasodilator Agents	2011
A galenical of traditional Chinese herbal mixture (THC-002) reduces expression of tachykinin peptides within urethras of spontaneously hypertensive rats. Neurourology and urodynamics, 2012, Volume: 31, Issue:1 Topics: Aging; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Hypertension; Male; Models, Animal; Neurokinin A; Neurokinin B; Rats; Rats, Inbred SHR; RNA, Messenger; Sodium Chloride; Substance P; Urethra	2012
Carotid body remodelling in l-NAME-induced hypertension in the rat. Journal of comparative pathology, 2012, Volume: 146, Issue:4 Topics: Animals; Biogenic Amines; Biomarkers; Blood Pressure; Carotid Body; Cell Nucleus; Disease Models, Animal; Enzyme Inhibitors; Fibrillar Collagens; Hypertension; Male; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Proteoglycans; Rats; Rats, Wistar; Substance P; Vascular Endothelial Growth Factor A	2012
Role of substance P in renal injury during DOCA-salt hypertension. Endocrinology, 2012, Volume: 153, Issue:12 Topics: Animals; Blood Pressure; Desoxycorticosterone; Hydroxyproline; Hypertension; Isoindoles; Kidney; Male; Mice; Mice, Inbred C57BL; Piperidines; Receptors, Neurokinin-1; Substance P; Telemetry; Time Factors	2012
Evaluation of the involvement of nitric oxide and substance P in reducing baroreflex gain in the genetically hypertensive (GH) rat. Acta physiologica Hungarica, 2002, Volume: 89, Issue:4 Topics: Animals; Baroreflex; Blood Pressure; Diterpenes; Enzyme Inhibitors; Heart Rate; Hypertension; Male; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Piperidines; Quinuclidines; Rats; Rats, Inbred SHR; Rest; Substance P; Vasoconstrictor Agents; Vasodilator Agents	2002
Impaired substance P release from renal sensory nerves in SHR involves a pertussis toxin-sensitive mechanism. American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 286, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Calcium; Dinoprostone; Dose-Response Relationship, Drug; Hypertension; In Vitro Techniques; Kidney Pelvis; Losartan; Neurons, Afferent; Osmolar Concentration; Pertussis Toxin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance P	2004
[Cerebral mechanisms in the genesis of arterial hypertension in emotional stress]. Vestnik Rossiiskoi akademii meditsinskikh nauk, 2003, Issue:12 Topics: Animals; Brain; Cardiovascular System; Conflict, Psychological; Electroencephalography; Hypertension; Rabbits; Rats; Stress, Psychological; Substance P	2003
The expression of VIP and SP in the cochlea of spontaneously hypertensive rats and its implication. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2004, Volume: 24, Issue:4 Topics: Animals; Cochlea; Hypertension; Rats; Rats, Inbred SHR; Rats, Wistar; Substance P; Vasoactive Intestinal Peptide	2004
Neurokininergic mechanism within the lateral crescent nucleus of the parabrachial complex participates in the heart-rate response to nociception. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Feb-09, Volume: 25, Issue:6 Topics: Afferent Pathways; Animals; Brachial Plexus; Decerebrate State; Efferent Pathways; Female; GABA Agonists; GABA-A Receptor Agonists; Heart Rate; Hypertension; Isonicotinic Acids; Male; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Piperidines; Pons; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Reflex; Spinal Cord; Substance P; Sympathetic Nervous System; Tachycardia	2005
[The expression and significance of VIP and SP in the cochlea of rats]. Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 2004, Volume: 18, Issue:11 Topics: Animals; Cochlea; Female; Hypertension; Labyrinth Diseases; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Substance P; Vasoactive Intestinal Peptide	2004
Increased substance P content in nerve fibers associated with mesenteric veins from deoxycorticosterone acetate (DOCA)-salt hypertensive rats. Regulatory peptides, 2006, Jan-15, Volume: 133, Issue:1-3 Topics: Animals; Body Weight; Calcitonin Gene-Related Peptide; Desoxycorticosterone; Dose-Response Relationship, Drug; Hypertension; Immunohistochemistry; Male; Mesenteric Arteries; Mesenteric Veins; Nerve Fibers; Neurons, Afferent; Neurotransmitter Agents; Peptide Fragments; Placebos; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Substance P	2006
Upregulation of tachykinin NK-1 and NK-3 receptor binding sites in the spinal cord of spontaneously hypertensive rat: impact on the autonomic control of blood pressure. British journal of pharmacology, 2006, Volume: 148, Issue:1 Topics: Acetates; Animals; Autonomic Nervous System; Autoradiography; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Indoles; Injections, Spinal; Male; Peptide Fragments; Piperidines; Quinolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Spinal Cord; Substance P; Thoracic Vertebrae; Up-Regulation	2006
Genetic manipulation of intraspinal plasticity after spinal cord injury alters the severity of autonomic dysreflexia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Mar-15, Volume: 26, Issue:11 Topics: Adenoviridae; Afferent Pathways; Animals; Autonomic Dysreflexia; Autonomic Fibers, Preganglionic; Axons; Bradycardia; Calcitonin Gene-Related Peptide; Colon; Cordotomy; Dilatation, Pathologic; Disease Models, Animal; Female; Genetic Therapy; Genetic Vectors; Hypertension; Microinjections; Nerve Growth Factor; Neuronal Plasticity; Pain; Posterior Horn Cells; Rats; Rats, Wistar; Recombinant Fusion Proteins; Rectum; Semaphorin-3A; Spinal Cord Injuries; Substance P; Vasoconstriction	2006
Differential effects of endothelin on activation of renal mechanosensory nerves: stimulatory in high-sodium diet and inhibitory in low-sodium diet. American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 291, Issue:5 Topics: Animals; Antihypertensive Agents; Diet, Sodium-Restricted; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelins; Ganglia, Spinal; Gene Expression Regulation; Hypertension; Kidney; Male; Mechanotransduction, Cellular; Neurons, Afferent; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Sodium, Dietary; Substance P	2006
Is dipeptidylpeptidase IV the missing link in angiotensin-converting enzyme inhibitor--induced angioedema? Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:1 Topics: Angioedema; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Enzyme Inhibitors; Humans; Hypertension; Neprilysin; Peptidyl-Dipeptidase A; Substance P	2008
Dipeptidyl peptidase IV in angiotensin-converting enzyme inhibitor associated angioedema. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:1 Topics: Adult; Aged; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Antigens; Bradykinin; Case-Control Studies; Dipeptidyl Peptidase 4; Female; Genetic Predisposition to Disease; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Substance P	2008
Alterations of brainstem and peripheral met-enkephalin and substance P levels in spontaneously hypertensive rats. Clinical and experimental hypertension. Part A, Theory and practice, 1984, Volume: 6, Issue:10-11 Topics: Age Factors; Animals; Brain Stem; Enkephalin, Methionine; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Opioid; Reticular Formation; Substance P; Trigeminal Nucleus, Spinal	1984
Blood pressure and heart rate responses to centrally administered substance P are increased in spontaneously hypertensive rats. Clinical science (London, England : 1979), 1980, Volume: 59 Suppl 6 Topics: Angiotensin II; Animals; Baclofen; Blood Pressure; Denervation; Dose-Response Relationship, Drug; Female; Heart Rate; Hypertension; Injections, Intraventricular; Male; Pressoreceptors; Rats; Substance P	1980
Plasma substance P levels in normotensive and hypertensive subjects. Clinical and experimental hypertension, 1981, Volume: 3, Issue:2 Topics: Diet; Humans; Hypertension; Posture; Radioimmunoassay; Sodium; Substance P	1981
Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: effects on nociceptive behavior and cardiovascular regulation. European journal of pharmacology, 1981, Jun-19, Volume: 72, Issue:2-3 Topics: Angiotensin II; Animals; Blood Pressure; Capsaicin; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hemodynamics; Hypertension; Male; Nociceptors; Norepinephrine; Rats; Rats, Inbred Strains; Substance P	1981
Action of substance P and an analogue on blood pressure and avoidance learning in rats with spontaneous hypertension (SHR). Die Pharmazie, 1981, Volume: 36, Issue:7 Topics: Animals; Autacoids; Avoidance Learning; Blood Pressure; Hypertension; Oligopeptides; Rats; Rats, Inbred Strains; Substance P	1981
[On the role of substance P in thermoregulation of normotensive and spontaneously hypertensive rats (author's transl)]. Die Pharmazie, 1982, Volume: 37, Issue:2 Topics: Animals; Body Temperature Regulation; Hypertension; Male; Naloxone; Rats; Rats, Inbred Strains; Substance P	1982
Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: effects on substance P contents of peripheral and central nervous system tissues. European journal of pharmacology, 1982, Jun-16, Volume: 81, Issue:1 Topics: Adrenal Medulla; Animals; Brain Chemistry; Capsaicin; Fatty Acids, Unsaturated; Ganglia, Sympathetic; Hypertension; Male; Nervous System; Rats; Rats, Inbred Strains; Substance P	1982
Action of substance P and an SP-hexapeptide analogue on avoidance learning in rats. Die Pharmazie, 1982, Volume: 37, Issue:11 Topics: Animals; Avoidance Learning; Hypertension; Oligopeptides; Rats; Rats, Inbred Strains; Substance P	1982
[Effect of substance P on blood pressure in rats, with and without hypokinetic stress]. Die Pharmazie, 1983, Volume: 38, Issue:4 Topics: Animals; Blood Pressure; Female; Hypertension; Rats; Restraint, Physical; Stress, Physiological; Substance P; Time Factors	1983
Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: neurochemical effects in the spinal cord. European journal of pharmacology, 1983, Aug-19, Volume: 92, Issue:1-2 Topics: Animals; Capsaicin; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Substance P	1983
[Behavior of blood pressure and substance P-like immunoreactivity (SPLIR) in plasma of rats with genetically fixed hypertension (SHR) under chronic intermittent immobilization]. Biomedica biochimica acta, 1983, Volume: 42, Issue:6 Topics: Animals; Blood Pressure; Humans; Hypertension; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Psychological; Substance P; Time Factors	1983
Action of substance P on the blood pressure of spontaneously hypertensive rats in dependence on age. Die Pharmazie, 1983, Volume: 38, Issue:9 Topics: Aging; Animals; Blood Pressure; Hypertension; Rats; Substance P	1983
Evidence of decreased plasma substance P levels in human essential hypertension and influence of prazosin treatment. Biomedica biochimica acta, 1983, Volume: 42, Issue:7-8 Topics: Adult; Blood Pressure; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Dopamine beta-Hydroxylase; Female; Humans; Hypertension; Male; Norepinephrine; Prazosin; Quinazolines; Renin; Substance P	1983
Substance P-like immunoreactivity in plasma and adrenal medulla of rats with spontaneous hypertension and WKY rats under acute stress. Biomedica biochimica acta, 1983, Volume: 42, Issue:7-8 Topics: Adrenal Medulla; Animals; Humans; Hypertension; Radioimmunoassay; Rats; Rats, Inbred Strains; Stress, Psychological; Substance P; Time Factors	1983
[Blood pressure and substance P-like immunoreactivity in the adrenal medulla and plasma of normotensive Wistar Kyoto rats and spontaneously hypertensive rats of varying age under acute stress]. Die Pharmazie, 1983, Volume: 38, Issue:12 Topics: Adrenal Medulla; Aging; Animals; Blood Pressure; Humans; Hypertension; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Stress, Psychological; Substance P	1983
Cardiovascular effects of a specific nonpeptide antagonist of substance P (NK-1) receptor in DOCA-salt hypertension. Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:6 Pt 2 Topics: Animals; Biphenyl Compounds; Blood Pressure; Cardiac Output; Cardiac Volume; Desoxycorticosterone; Heart Rate; Hemodynamics; Hypertension; Hypnotics and Sedatives; Male; Neurokinin-1 Receptor Antagonists; Rats; Rats, Wistar; Sodium Chloride; Substance P; Vascular Resistance	1995
[The role of arginine-vasopressin and substance P in the pathogenesis of hypertension and their interrelation]. Zhonghua nei ke za zhi, 1993, Volume: 32, Issue:5 Topics: Adult; Aged; Antihypertensive Agents; Arginine Vasopressin; Female; Humans; Hypertension; Male; Middle Aged; Substance P	1993
Decreases in substance P and vasoactive intestinal peptide concentrations in plasma of stroke-prone spontaneously hypertensive rats. Japanese heart journal, 1993, Volume: 34, Issue:6 Topics: Animals; Cerebrovascular Disorders; Hypertension; Immunoenzyme Techniques; Male; Peripheral Nerves; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance P; Vasoactive Intestinal Peptide	1993
Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats. Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:2 Topics: Animals; Arginine; Chronic Disease; Hypertension; Hypoxia; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Substance P; Vasoconstriction	1994
Impaired endothelium-dependent vasodilation in patients with essential hypertension: evidence that the abnormality is not at the muscarinic receptor level. Journal of the American College of Cardiology, 1994, Volume: 23, Issue:7 Topics: Acetylcholine; Arginine; Endothelium, Vascular; Female; Forearm; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Receptors, Muscarinic; Substance P; Vasodilation	1994
Impaired endothelium-dependent vasodilation of large epicardial and resistance coronary arteries in patients with essential hypertension. Different responses to acetylcholine and substance P. Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:2 Topics: Acetylcholine; Adult; Arteries; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Pericardium; Substance P; Vascular Resistance; Vasodilation	1995
Intrathecal capsaicin enhances one-kidney renal wrap hypertension in the rat. Journal of the autonomic nervous system, 1994, Dec-15, Volume: 50, Issue:2 Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Desoxycorticosterone; Hypertension; Hypertension, Renovascular; Immunohistochemistry; Injections, Spinal; Male; Nerve Degeneration; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P	1994
A comparative study by retrograde neuronal tracing and substance P immunohistochemistry of sympathetic preganglionic neurons in spontaneously hypertensive rats and Wistar-Kyoto rats. Journal of anatomy, 1995, Volume: 186 ( Pt 1) Topics: Adrenergic Fibers; Animals; Autonomic Fibers, Preganglionic; Cell Count; Cholera Toxin; Dendrites; Fluorescent Dyes; Horseradish Peroxidase; Hypertension; Immunohistochemistry; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spinal Cord; Stilbamidines; Substance P	1995
Angiotensin converting enzyme (ACE) inhibitor-induced cough and substance P. Thorax, 1996, Volume: 51, Issue:2 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Cough; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Sputum; Substance P; Time Factors	1996
Effects of repeated sensory stimulation (electro-acupuncture) and physical exercise (running) on open-field behaviour and concentrations of neuropeptides in the hippocampus in WKY and SHR rats. The European journal of neuroscience, 1996, Volume: 8, Issue:2 Topics: Animals; Depression; Electric Stimulation; Electroacupuncture; Exploratory Behavior; Galanin; Hippocampus; Hypertension; Male; Neurokinin A; Neuropeptide Y; Neuropeptides; Physical Exertion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance P; Vasoactive Intestinal Peptide	1996
Association and cosegregation of stroke with impaired endothelium-dependent vasorelaxation in stroke prone, spontaneously hypertensive rats. The Journal of clinical investigation, 1996, Jul-15, Volume: 98, Issue:2 Topics: Acetylcholine; Animals; Aorta, Thoracic; Basilar Artery; Blood Pressure; Cerebrovascular Disorders; Crosses, Genetic; Disease Susceptibility; Endothelium, Vascular; Female; Heart Rate; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroglycerin; Nitroprusside; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Serotonin; Substance P; Vasodilation	1996
Coronary vascular nitric oxide activity in hypertension and hypercholesterolemia. Comparison of acetylcholine and substance P. Circulation, 1997, Jan-07, Volume: 95, Issue:1 Topics: Acetylcholine; Adult; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Reference Values; Substance P; Vascular Resistance; Vasodilation	1997
Role of substance P in blood pressure regulation in salt-dependent experimental hypertension. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:1 Pt 2 Topics: Animals; Biphenyl Compounds; Blood Pressure; Desoxycorticosterone; Hypertension; Male; Neurokinin-1 Receptor Antagonists; Rats; Rats, Inbred WKY; Substance P; Vasodilator Agents	1997
Distinct endothelial impairment in coronary microvessels from hypertensive Dahl rats. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2 Topics: Acetylcholine; Animals; Bradykinin; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Endothelium, Vascular; Fatty Acids, Unsaturated; Hypertension; In Vitro Techniques; Indomethacin; Male; Microcirculation; Nitroarginine; Rats; Rats, Inbred Strains; Sodium, Dietary; Substance P; Vasodilation	1998
Renal substance P-containing neurons and substance P receptors impaired in hypertension. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Enzyme Activation; Hypertension; Kidney Pelvis; Male; Neurons, Afferent; Pelvic Exenteration; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neurokinin-1; Substance P	1998
Role of corticotropin-releasing factor and substance P in pressor responses of nuclei controlling emotion and stress. Peptides, 1998, Volume: 19, Issue:4 Topics: Animals; Blood Pressure; Brain; Corticotropin-Releasing Hormone; Heart Rate; Hypertension; Male; Microinjections; Prosencephalon; Rats; Rhombencephalon; Stress, Psychological; Substance P	1998
ACE inhibitors and symptomless dysphagia. Lancet (London, England), 1998, Jul-11, Volume: 352, Issue:9122 Topics: Angiotensin-Converting Enzyme Inhibitors; Case-Control Studies; Cerebral Hemorrhage; Cerebral Infarction; Cough; Deglutition Disorders; Female; Humans; Hypertension; Male; Substance P	1998
Neurokinin-1 receptors and spinal cord control of blood pressure in spontaneously hypertensive rats. Brain research, 1999, Jan-02, Volume: 815, Issue:1 Topics: Analgesics; Animals; Blood Pressure; Heart Rate; Hypertension; Indoles; Injections, Spinal; Isoindoles; Neurons; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neurokinin-1; Spinal Cord; Substance P; Sympathetic Nervous System	1999
Decreased vascular permeability response to substance P in airways of genetically hypertensive rats. British journal of pharmacology, 1999, Volume: 126, Issue:4 Topics: Animals; Blood Pressure; Capillary Permeability; Capsaicin; Hypertension; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P	1999
Reduced inflammation in genetically hypertensive rat airways is associated with reduced tachykinin NK(1) receptor numbers. European journal of pharmacology, 2000, Jul-28, Volume: 401, Issue:1 Topics: Animals; Binding, Competitive; Capillary Permeability; Diterpenes; Hypertension; Inflammation; Male; Membranes; Piperidines; Quinuclidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Spinal Cord; Substance P; Trachea; Tritium	2000
Cyclosporine A-induced hypertension involves synapsin in renal sensory nerve endings. Proceedings of the National Academy of Sciences of the United States of America, 2000, Aug-15, Volume: 97, Issue:17 Topics: Afferent Pathways; Animals; Blood Pressure; Capsaicin; Cyclosporine; Disease Models, Animal; Female; Hypertension; Immunohistochemistry; Immunophilins; Kidney; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Endings; Neurons, Afferent; rab3A GTP-Binding Protein; Substance P; Sympathetic Nervous System; Synapsins; Synaptic Vesicles	2000
Increased ganglionic responses to substance P in hypertensive rats due to upregulation of NK(1) receptors. American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:5 Topics: Animals; Autoradiography; Ganglia, Sympathetic; Heart Rate; Hypertension; Kidney; Male; Peptide Fragments; Physalaemin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P	2000
Angiotensin-converting enzyme inhibitors, angiotensin-II receptor antagonists, and pneumonia in elderly hypertensive patients with stroke. Chest, 2001, Volume: 119, Issue:2 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Pneumonia; Stroke; Substance P	2001
[No relation between angiotensin-converting enzyme (ACE) inhibitor-induced cough and ACE gene polymorphism, plasma bradykinin, substance P and ACE inhibitor concentration in Japanese patients]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2001, Volume: 121, Issue:3 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Chronic Disease; Cough; Female; Humans; Hypertension; Indoles; Male; Middle Aged; Nephritis; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Substance P	2001
[Study on changes of plasma substance P in essential hypertension with left ventricular hypertrophy patients and the effect of promoting blood circulation and eliminating phlegm]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1998, Volume: 18, Issue:6 Topics: Aged; Angiotensin II; Drugs, Chinese Herbal; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Substance P	1998
Role of calcitonin gene-related peptide and substance P in Dahl-salt hypertension. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3 Pt 2 Topics: Animals; Blood Pressure; Blotting, Northern; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Ganglia, Spinal; Hemodynamics; Hypertension; Male; Peptide Fragments; Radioimmunoassay; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; RNA, Messenger; Substance P	2001
Substance P in subtotal nephrectomy-salt hypertension. Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:2 Pt 2 Topics: Animals; Blood Pressure; Hemodynamics; Hypertension; Male; Nephrectomy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Salts; Substance P	2002
Involvement of rat lateral septum-acetylcholine pressor system in central amygdaloid nucleus-emotional pressor circuit. Neuroscience letters, 2002, Apr-19, Volume: 323, Issue:1 Topics: Acetylcholine; Amygdala; Animals; Atropine; Corticotropin-Releasing Hormone; Glutamic Acid; Habenula; Hypertension; Hypothalamus; Locus Coeruleus; Male; Medulla Oblongata; Muscarinic Antagonists; Rats; Rats, Wistar; Septal Nuclei; Stress, Psychological; Substance P	2002
Depressor and tachypneic responses to chemical stimulation of the ventral respiratory group are reduced by ablation of neurokinin-1 receptor-expressing neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, May-01, Volume: 22, Issue:9 Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cell Count; Dose-Response Relationship, Drug; Homocysteine; Hypertension; Hypotension; Immunotoxins; Male; Medulla Oblongata; Microinjections; N-Glycosyl Hydrolases; Neurons; Phrenic Nerve; Plant Proteins; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Recombinant Fusion Proteins; Respiration; Respiratory Physiological Phenomena; Ribosome Inactivating Proteins, Type 1; Saporins; Substance P	2002
Electrophysiological effects of tachykinin agonists on sympathetic ganglia of spontaneously hypertensive rats. Autonomic neuroscience : basic & clinical, 2002, Apr-18, Volume: 97, Issue:1 Topics: Analysis of Variance; Animals; Blood Pressure; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Ganglia, Sympathetic; Heart Rate; Hypertension; Male; Membrane Potentials; Neurons; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neurokinin-1; Receptors, Tachykinin; Substance P; Tachykinins	2002
Action of substance P on neurotico-hypertensive rats. Die Pharmazie, 1979, Volume: 34, Issue:10 Topics: Animals; Behavior, Animal; Blood Pressure; Conditioning, Classical; Decision Making; Hypertension; Learning; Male; Memory; Prejudice; Rats; Retention, Psychology; Substance P	1979
Circulating immunoreactive substance P in man. Irish journal of medical science, 1976, Volume: 145, Issue:12 Topics: Adult; Aged; Atrial Fibrillation; Colitis, Ulcerative; Female; Humans; Hypertension; Kidney Failure, Chronic; Liver Neoplasms; Male; Radioimmunoassay; Substance P	1976
Sensory nerve terminal activity in severe hypertension as reflected by circulating calcitonin gene-related peptide (CGRP) and substance P. Blood pressure, 1992, Volume: 1, Issue:4 Topics: Adult; Aged; Blood Pressure; Calcitonin Gene-Related Peptide; Chromatography, High Pressure Liquid; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Neurons, Afferent; Substance P; Time Factors	1992
Pharmacology of idrapril: a new class of angiotensin converting enzyme inhibitors. Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:1 Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bronchoconstriction; Capsaicin; Captopril; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Hydroxylamines; Hypertension; In Vitro Techniques; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Substance P	1992
[Producing a "defense reaction" by substance P. Can neuropeptides contribute to the development of hypertension?]. Fortschritte der Medizin, 1990, Apr-30, Volume: 108, Issue:13 Topics: Animals; Arousal; Humans; Hypertension; Male; Neuropeptides; Rats; Substance P	1990
Perivascular innervation of the cerebral arteries in spontaneously hypertensive rats--an immunohistochemical study. Angiology, 1991, Volume: 42, Issue:2 Topics: Adrenergic Fibers; Animals; Brain Diseases; Cerebral Arteries; Cholinergic Fibers; Hypertension; Immunohistochemistry; Male; Neuropeptide Y; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance P; Vasoactive Intestinal Peptide; Vasoconstriction; Vasodilation	1991
Neurophysiological effects of substance P in primate hypertension models. Preliminary report. Cor et vasa, 1990, Volume: 32, Issue:6 Topics: Animals; Arousal; Blood Pressure; Brain; Brain Mapping; Evoked Potentials; Frontal Lobe; Hypertension; Locus Coeruleus; Macaca mulatta; Neural Inhibition; Papio; Raphe Nuclei; Substance P	1990
[The effect of substance P on the individual and group behaviors of rhesus monkeys]. Nauchnye doklady vysshei shkoly. Biologicheskie nauki, 1991, Issue:3 Topics: Animals; Behavior, Animal; Blood Pressure; Chronic Disease; Group Processes; Hierarchy, Social; Hypertension; Macaca mulatta; Male; Restraint, Physical; Stress, Psychological; Substance P	1991
The role of substance P of the central nervous system in the pathogenesis of spontaneously hypertensive rats. Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, 1990, Volume: 5, Issue:3 Topics: Animals; Blood Pressure; Central Nervous System; Hypertension; Hypothalamus; Medulla Oblongata; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Spinal Cord; Substance P	1990
Effects of substance P on norepinephrine release from vascular adrenergic neurons in spontaneously hypertensive rats. American journal of hypertension, 1991, Volume: 4, Issue:4 Pt 1 Topics: Adrenergic Fibers; Animals; Blood Pressure; Electric Stimulation; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance P	1991
[The role of plasma substance P and catecholamines in hypertension]. Zhonghua xin xue guan bing za zhi, 1991, Volume: 19, Issue:1 Topics: Adult; Animals; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance P	1991
Decreased spinal cord content of calcitonin gene-related peptide in the spontaneously hypertensive rat. Neuroscience letters, 1991, Oct-14, Volume: 131, Issue:2 Topics: Animals; Blood Pressure; Body Weight; Calcitonin Gene-Related Peptide; Calcium; Calcium, Dietary; Homeostasis; Hypertension; Immunohistochemistry; Male; Neurons; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spinal Cord; Substance P	1991
Are genetically hypertensive rats deficient in nerve growth factor? Neuroreport, 1991, Volume: 2, Issue:1 Topics: Animals; Axons; Cell Count; Ganglia, Sympathetic; Hypertension; Immunologic Techniques; Nerve Growth Factors; Neurons; Rats; Rats, Inbred SHR; Substance P	1991
Endogenous opioid dependence--a basic pathophysiological phenomenon of stress-induced and genetically fixed disturbances in adaptation--influence of substance P. Die Pharmazie, 1991, Volume: 46, Issue:10 Topics: Adaptation, Physiological; Animals; Blood Pressure; Endorphins; Hypertension; Ileum; Immobilization; In Vitro Techniques; Male; Muscle, Smooth; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Stress, Psychological; Substance P; Substance-Related Disorders	1991
[Experimental study on the treatment of hypertension with combined traditional Chinese and Western medicine]. Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1991, Volume: 11, Issue:11 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Atrial Natriuretic Factor; Cyclic AMP; Cyclic GMP; Drugs, Chinese Herbal; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Substance P; Thromboxane B2	1991
Arterial blood-pressure change and endogenous circulating substance P in man. Clinical physiology (Oxford, England), 1985, Volume: 5, Issue:4 Topics: Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Hypotension; Male; Middle Aged; Pressoreceptors; Reflex; Substance P; Trimethaphan	1985
Alterations in substance P binding in brain nuclei of spontaneously hypertensive rats. The American journal of physiology, 1987, Volume: 252, Issue:2 Pt 2 Topics: Aging; Animals; Autoradiography; Binding Sites; Blood Pressure; Brain; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance P; Tissue Distribution	1987
Neurochemical differences in the superior cervical ganglion of the spontaneously hypertensive rat stroke-prone variant. Brain research, 1987, Jul-07, Volume: 415, Issue:1 Topics: Animals; Catecholamines; Cerebrovascular Disorders; Cyclic AMP; Cyclic GMP; Ganglia, Sympathetic; Hypertension; Neuropeptides; Nucleotides, Cyclic; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Somatostatin; Substance P	1987
Peptide-containing nerves around blood vessels of stroke-prone spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:2 Pt 2 Topics: Animals; Blood Vessels; Cerebral Arteries; Hypertension; Male; Mesenteric Arteries; Neuropeptide Y; Neuropeptides; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Substance P; Vasoactive Intestinal Peptide	1988
Substance P in human essential hypertension. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 12 Topics: Adult; Blood Pressure; Captopril; Humans; Hypertension; Norepinephrine; Prazosin; Stress, Psychological; Substance P	1987
Decreased SP-stimulated diesteratic hydrolysis of inositol phospholipids in adrenal medulla slices from spontaneously hypertensive rats. Biomedica biochimica acta, 1988, Volume: 47, Issue:1 Topics: Adrenal Medulla; Animals; Hydrolysis; Hypertension; Inositol; Male; Phosphates; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphatidylserines; Phosphorus Radioisotopes; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance P	1988
Angiotensin-converting enzyme inhibition, cough and the serum concentration of substance P. European journal of clinical pharmacology, 1988, Volume: 34, Issue:6 Topics: Angiotensin-Converting Enzyme Inhibitors; Cough; Enalapril; Humans; Hypertension; Substance P	1988
[Long-term hypotensive effects of substance P on the stress induced hypertension of primates]. Biomedica biochimica acta, 1988, Volume: 47, Issue:3 Topics: Animals; Blood Pressure; Hypertension; Primates; Stress, Physiological; Substance P	1988
Role of substance P and neurotensin in the regulation of neurosecretion and vascular responsiveness in hypertension. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4 Topics: Animals; Electric Stimulation; Hypertension; Mesentery; Neurotensin; Norepinephrine; Rats; Rats, Inbred Strains; Substance P; Vasomotor System	1988
Substance P immunoreactivity in the superior cervical ganglia of normotensive and genetically hypertensive rats. Journal of the autonomic nervous system, 1989, Volume: 27, Issue:3 Topics: Aging; Animals; Capsaicin; Ganglia, Sympathetic; Hypertension; Neurons, Afferent; Neuropeptide Y; Rats; Rats, Inbred Strains; Substance P	1989
Reduced levels of calcitonin gene-related peptide (CGRP) but not substance P during and after treatment of severe hypertension in man. Journal of human hypertension, 1989, Volume: 3, Issue:4 Topics: Adrenergic beta-Antagonists; Adult; Afferent Pathways; Aged; Blood Pressure; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Diuretics; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Radioimmunoassay; Substance P	1989
Different patterns of immunolocalization of calcitonin gene-related peptide and substance P in sympathetic ganglia of normotensive and genetically hypertensive rats. Neuroscience letters, 1989, Nov-20, Volume: 106, Issue:1-2 Topics: Animals; Calcitonin Gene-Related Peptide; Ganglia, Sympathetic; Hypertension; Immunohistochemistry; Rats; Rats, Inbred Strains; Substance P	1989
Circulating perivascular dilatory neuropeptides in hypertension. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6 Topics: Adult; Aged; Antihypertensive Agents; Calcitonin Gene-Related Peptide; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Neuropeptides; Substance P; Vasoactive Intestinal Peptide; Vasodilation	1989