Compounds > beta-aminoethyl isothiourea
Page last updated: 2024-09-20

beta-aminoethyl isothiourea

Description

beta-Aminoethyl Isothiourea: A radiation-protective agent that can inhibit DNA damage by binding to the DNA. It also increases the susceptibility of blood cells to complement-mediated lysis. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID2039
CHEMBL ID454761
SCHEMBL ID233483
MeSH IDM0330729

Synonyms (58)

Synonym
AKOS005431477
2-(2-aminoethyl)isothiourea
pseudourea, 2-(2-amino-ethyl)-2-thio-
carbamimidothioic acid, 2-aminoethyl ester
s-(2-aminoethyl)isothiuronium
2-aminoethylisothiuronium
beta-aminoethylisothiourea
brn 1747215
(2-aminoethyl)isothiourea
2-aminoethyl carbamimidothioate
s-(beta-aminoethyl)isothiouronium
aminoethylisothiuronium
s-(2-aminoethyl)isothiourea
pseudourea, 2-(2-aminoethyl)-2-thio-
beta-aminoethyl isothiourea
tocris-0893
NCGC00015071-01
lopac-a-5879
NCGC00024851-01
BSPBIO_002520
LOPAC0_000078
NCGC00024851-02
STK386774
NCGC00015071-04
151-16-6
bdbm50271880
2-(2-amino-ethyl)-isothiourea
CHEMBL454761 ,
EN300-81702
[(2-aminoethyl)sulfanyl]methanimidamide
CCG-204173
ae-itu
unii-2gih68g0mx
2gih68g0mx ,
4-04-00-01575 (beilstein handbook reference)
NCGC00015071-02
NCGC00015071-03
aminoethylisothiourea
.beta.-aminoethyl isothiourea
SCHEMBL233483
s-(.beta.-aminoethyl)isothiouronium
surrectan (salt/mix)
2-aminoethyl imidothiocarbamate #
2-.beta.-aminoethylisothiourea
pseudourea, (2-aminoethyl)-2-thio-, dihydrobromide (salt/mix)
NWPCXGGYSQHQGM-UHFFFAOYSA-N
antirad (salt/mix)
.beta.-aminoethylisothiourea
aet (salt/mix)
.beta.-aminoethylisothiuronium
aminoethylisothiourea dihydrobromide
beta-aminoethylisothiuronium
CS-0266576
SDCCGSBI-0050066.P002
NCGC00015071-08
Q27254714
DTXSID60871531
PD074440

Protein Targets (14)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency14.12540.004023.8416100.0000AID485290
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency25.05940.140911.194039.8107AID2451
thioredoxin reductaseRattus norvegicus (Norway rat)Potency14.12540.100020.879379.4328AID588453
GLS proteinHomo sapiens (human)Potency35.48130.35487.935539.8107AID624146
TDP1 proteinHomo sapiens (human)Potency14.31760.000811.382244.6684AID686978; AID686979
Microtubule-associated protein tauHomo sapiens (human)Potency31.62280.180013.557439.8107AID1460
thyroid stimulating hormone receptorHomo sapiens (human)Potency5.01190.001318.074339.8107AID926; AID938
arylsulfatase AHomo sapiens (human)Potency0.01691.069113.955137.9330AID720538
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency3.16230.035520.977089.1251AID504332
cytochrome P450 2C19 precursorHomo sapiens (human)Potency25.11890.00255.840031.6228AID899
muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)Potency0.02820.00106.000935.4813AID943
lethal factor (plasmid)Bacillus anthracis str. A2012Potency31.62280.020010.786931.6228AID912
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency42.56150.060110.745337.9330AID485368
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Nitric oxide synthase, brainHomo sapiens (human)Ki1.80000.01501.18117.3000AID404423
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (34)

Processvia Protein(s)Taxonomy
response to hypoxiaNitric oxide synthase, brainHomo sapiens (human)
regulation of sodium ion transportNitric oxide synthase, brainHomo sapiens (human)
arginine catabolic processNitric oxide synthase, brainHomo sapiens (human)
nitric oxide biosynthetic processNitric oxide synthase, brainHomo sapiens (human)
striated muscle contractionNitric oxide synthase, brainHomo sapiens (human)
myoblast fusionNitric oxide synthase, brainHomo sapiens (human)
response to heatNitric oxide synthase, brainHomo sapiens (human)
negative regulation of calcium ion transport into cytosolNitric oxide synthase, brainHomo sapiens (human)
regulation of cardiac muscle contraction by calcium ion signalingNitric oxide synthase, brainHomo sapiens (human)
peptidyl-cysteine S-nitrosylationNitric oxide synthase, brainHomo sapiens (human)
positive regulation of peptidyl-serine phosphorylationNitric oxide synthase, brainHomo sapiens (human)
multicellular organismal response to stressNitric oxide synthase, brainHomo sapiens (human)
xenobiotic catabolic processNitric oxide synthase, brainHomo sapiens (human)
vasodilationNitric oxide synthase, brainHomo sapiens (human)
negative regulation of potassium ion transportNitric oxide synthase, brainHomo sapiens (human)
cell redox homeostasisNitric oxide synthase, brainHomo sapiens (human)
positive regulation of DNA-templated transcriptionNitric oxide synthase, brainHomo sapiens (human)
positive regulation of transcription by RNA polymerase IINitric oxide synthase, brainHomo sapiens (human)
negative regulation of hydrolase activityNitric oxide synthase, brainHomo sapiens (human)
negative regulation of serotonin uptakeNitric oxide synthase, brainHomo sapiens (human)
negative regulation of calcium ion transportNitric oxide synthase, brainHomo sapiens (human)
regulation of cardiac muscle contractionNitric oxide synthase, brainHomo sapiens (human)
regulation of ryanodine-sensitive calcium-release channel activityNitric oxide synthase, brainHomo sapiens (human)
cellular response to growth factor stimulusNitric oxide synthase, brainHomo sapiens (human)
positive regulation of the force of heart contractionNitric oxide synthase, brainHomo sapiens (human)
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathwayNitric oxide synthase, brainHomo sapiens (human)
positive regulation of sodium ion transmembrane transportNitric oxide synthase, brainHomo sapiens (human)
regulation of calcium ion transmembrane transport via high voltage-gated calcium channelNitric oxide synthase, brainHomo sapiens (human)
positive regulation of membrane repolarization during ventricular cardiac muscle cell action potentialNitric oxide synthase, brainHomo sapiens (human)
positive regulation of guanylate cyclase activityNitric oxide synthase, brainHomo sapiens (human)
nitric oxide mediated signal transductionNitric oxide synthase, brainHomo sapiens (human)
response to hormoneNitric oxide synthase, brainHomo sapiens (human)
negative regulation of blood pressureNitric oxide synthase, brainHomo sapiens (human)
response to lipopolysaccharideNitric oxide synthase, brainHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (15)

Processvia Protein(s)Taxonomy
nitric-oxide synthase activityNitric oxide synthase, brainHomo sapiens (human)
calcium channel regulator activityNitric oxide synthase, brainHomo sapiens (human)
protein bindingNitric oxide synthase, brainHomo sapiens (human)
calmodulin bindingNitric oxide synthase, brainHomo sapiens (human)
FMN bindingNitric oxide synthase, brainHomo sapiens (human)
sodium channel regulator activityNitric oxide synthase, brainHomo sapiens (human)
heme bindingNitric oxide synthase, brainHomo sapiens (human)
tetrahydrobiopterin bindingNitric oxide synthase, brainHomo sapiens (human)
arginine bindingNitric oxide synthase, brainHomo sapiens (human)
transmembrane transporter bindingNitric oxide synthase, brainHomo sapiens (human)
cadmium ion bindingNitric oxide synthase, brainHomo sapiens (human)
calcium-dependent protein bindingNitric oxide synthase, brainHomo sapiens (human)
flavin adenine dinucleotide bindingNitric oxide synthase, brainHomo sapiens (human)
NADP bindingNitric oxide synthase, brainHomo sapiens (human)
scaffold protein bindingNitric oxide synthase, brainHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (17)

Processvia Protein(s)Taxonomy
photoreceptor inner segmentNitric oxide synthase, brainHomo sapiens (human)
nucleoplasmNitric oxide synthase, brainHomo sapiens (human)
cytoplasmNitric oxide synthase, brainHomo sapiens (human)
mitochondrionNitric oxide synthase, brainHomo sapiens (human)
cytosolNitric oxide synthase, brainHomo sapiens (human)
cytoskeletonNitric oxide synthase, brainHomo sapiens (human)
plasma membraneNitric oxide synthase, brainHomo sapiens (human)
sarcoplasmic reticulumNitric oxide synthase, brainHomo sapiens (human)
sarcolemmaNitric oxide synthase, brainHomo sapiens (human)
dendritic spineNitric oxide synthase, brainHomo sapiens (human)
membrane raftNitric oxide synthase, brainHomo sapiens (human)
synapseNitric oxide synthase, brainHomo sapiens (human)
perinuclear region of cytoplasmNitric oxide synthase, brainHomo sapiens (human)
cell peripheryNitric oxide synthase, brainHomo sapiens (human)
protein-containing complexNitric oxide synthase, brainHomo sapiens (human)
plasma membraneNitric oxide synthase, brainHomo sapiens (human)
postsynaptic densityNitric oxide synthase, brainHomo sapiens (human)
cytosolNitric oxide synthase, brainHomo sapiens (human)
nucleusNitric oxide synthase, brainHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (20)

Assay IDTitleYearJournalArticle
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588378qHTS for Inhibitors of ATXN expression: Validation
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID588349qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay
AID1347057CD47-SIRPalpha protein protein interaction - LANCE assay qHTS validation2019PloS one, , Volume: 14, Issue:7
Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID504836Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in human glioma: Validation2002The Journal of biological chemistry, Apr-19, Volume: 277, Issue:16
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347405qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS LOPAC collection2020ACS chemical biology, 07-17, Volume: 15, Issue:7
High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID1347049Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot screen2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID1347050Natriuretic polypeptide receptor (hNpr2) antagonism - Pilot subtype selectivity assay2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID1347045Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot counterscreen GloSensor control cell line2019Science translational medicine, 07-10, Volume: 11, Issue:500
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1508630Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay2021Cell reports, 04-27, Volume: 35, Issue:4
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID1347151Optimization of GU AMC qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347410qHTS for inhibitors of adenylyl cyclases using a fission yeast platform: a pilot screen against the NCATS LOPAC library2019Cellular signalling, 08, Volume: 60A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening.
AID1347059CD47-SIRPalpha protein protein interaction - Alpha assay qHTS validation2019PloS one, , Volume: 14, Issue:7
Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1347058CD47-SIRPalpha protein protein interaction - HTRF assay qHTS validation2019PloS one, , Volume: 14, Issue:7
Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID404423Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrulline2008Bioorganic & medicinal chemistry, Jun-01, Volume: 16, Issue:11
Design, synthesis, and evaluation of potential inhibitors of nitric oxide synthase.
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (627)

TimeframeStudies, This Drug (%)All Drugs %
pre-1990556 (88.68)18.7374
1990's45 (7.18)18.2507
2000's10 (1.59)29.6817
2010's9 (1.44)24.3611
2020's7 (1.12)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews27 (3.55%)6.00%
Case Studies3 (0.39%)4.05%
Observational0 (0.00%)0.25%
Other730 (96.05%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
imidazole[no description available]medium10imidazole
s,s'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea[no description available]medium10
pimagedine[no description available]medium30guanidines;
one-carbon compound		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
EC 1.4.3.4 (monoamine oxidase) inhibitor
2-aminothiazole[no description available]medium101,3-thiazoles;
primary amino compound
s-ethyl n-(4-(trifluoromethyl)phenyl)isothiourea[no description available]medium10
etiron[no description available]medium30
s-methylisothiopseudouronium[no description available]medium30
2-aminothiazoline[no description available]medium401,3-thiazoles;
primary amino compound
n-(4-nitrophenacyl)imidazole[no description available]medium10
1-phenylimidazole[no description available]medium10
3,5-dimethylpyrazole-1-carboxamidine[no description available]medium10
n(g)-iminoethylornithine[no description available]medium10L-alpha-amino acid
2-amino-5-methylthiazole[no description available]medium10
nitroarginine[no description available]medium30guanidines;
L-arginine derivative;
N-nitro compound;
non-proteinogenic L-alpha-amino acid
vinyl-l-nio[no description available]medium10
pyrazole-1-carboxamidine[no description available]medium10
1-(4-(3-bromophenoxy)butyl)-1h-imidazole[no description available]medium10
thiourea[no description available]medium470one-carbon compound;
thioureas;
ureas		antioxidant;
chromophore
pentetic acid[no description available]medium30pentacarboxylic acidcopper chelator
edetic acid[no description available]medium40ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
n-vinyl-2-pyrrolidinone[no description available]medium10pyrrolidin-2-ones
cysteine[no description available]medium720cysteiniumfundamental metabolite
sodium nitrite[no description available]medium10inorganic sodium salt;
nitrite salt		antidote to cyanide poisoning;
antihypertensive agent;
antimicrobial food preservative;
food antioxidant;
poison
quercetin[no description available]medium107-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger
n-acetylneuraminic acid[no description available]medium10N-acetylneuraminic acidsantioxidant;
bacterial metabolite;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
human metabolite;
mouse metabolite
thomsen-friedenreich antigen[no description available]medium10
5-methoxytryptamine[no description available]medium190aromatic ether;
primary amino compound;
tryptamines		5-hydroxytryptamine 2A receptor agonist;
5-hydroxytryptamine 2B receptor agonist;
5-hydroxytryptamine 2C receptor agonist;
antioxidant;
cardioprotective agent;
human metabolite;
mouse metabolite;
neuroprotective agent;
radiation protective agent;
serotonergic agonist
thiazoles[no description available]medium1201,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
beta carotene[no description available]medium10carotenoid beta-end derivative;
cyclic carotene		antioxidant;
biological pigment;
cofactor;
ferroptosis inhibitor;
human metabolite;
mouse metabolite;
plant metabolite;
provitamin A
glycine[no description available]medium10alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
chlorine[no description available]medium10halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
2-mercaptoethylguanidine[no description available]medium60
isothiuronium[no description available]medium80
bromide[no description available]medium70halide anion;
monoatomic bromine
cysteamine[no description available]medium1090amine;
thiol		geroprotector;
human metabolite;
mouse metabolite;
radiation protective agent
mechlorethamine[no description available]medium70nitrogen mustard;
organochlorine compound		alkylating agent
dimethyl sulfoxide[no description available]medium80sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
dimaprit[no description available]medium30imidothiocarbamic ester
thymidine[no description available]medium190pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
heroin[no description available]medium10morphinane alkaloidmu-opioid receptor agonist;
opioid analgesic;
prodrug
phosphorus[no description available]medium20monoatomic phosphorus;
nonmetal atom;
pnictogen		macronutrient
triethylenemelamine[no description available]medium101,3,5-triazinesalkylating agent;
insect sterilant
busulfan[no description available]medium20methanesulfonate esteralkylating agent;
antineoplastic agent;
carcinogenic agent;
insect sterilant;
teratogenic agent
adrenochrome[no description available]medium10indoles
carbazochrome[no description available]medium10
vitamin k semiquinone radical[no description available]medium20
cystamine[no description available]medium750organic disulfide;
primary amino compound		EC 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitor
pentobarbital[no description available]medium40barbituratesGABAA receptor agonist
alanine[no description available]medium60alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite
sulfur[no description available]medium50chalcogen;
nonmetal atom		macronutrient
cystine[no description available]medium30
urea[no description available]medium10isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
thioctic acid[no description available]medium40dithiolanes;
heterocyclic fatty acid;
thia fatty acid		fundamental metabolite;
geroprotector
trifluoperazine[no description available]medium10N-alkylpiperazine;
N-methylpiperazine;
organofluorine compound;
phenothiazines		antiemetic;
calmodulin antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor;
phenothiazine antipsychotic drug
phenelzine[no description available]medium10primary amine
idoxuridine[no description available]medium20organoiodine compound;
pyrimidine 2'-deoxyribonucleoside		antiviral drug;
DNA synthesis inhibitor
d-alpha tocopherol[no description available]medium20alpha-tocopherolalgal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite
cyanides[no description available]medium30pseudohalide anionEC 1.9.3.1 (cytochrome c oxidase) inhibitor
4-aminopropiophenone[no description available]medium30
nadp[no description available]medium20
chloroethylaminouracil[no description available]medium10
uracil mustard[no description available]medium10aminouracil;
nitrogen mustard
thiazolidine-4-carboxylic acid[no description available]medium10alpha-amino acid zwitterion;
non-proteinogenic alpha-amino acid;
sulfur-containing amino acid;
thiazolidinemonocarboxylic acid		antidote;
antioxidant;
hepatoprotective agent
valine[no description available]medium10L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
thiazolidines[no description available]medium10thiazolidine
ascorbic acid[no description available]medium50ascorbic acid;
vitamin C		coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent
vanadium[no description available]medium10elemental vanadium;
vanadium group element atom		micronutrient
chromium[no description available]medium10chromium group element atom;
metal allergen		micronutrient
meturedepa[no description available]medium20phosphoramide
dactinomycin[no description available]medium20actinomycinmutagen
carbamates[no description available]medium20amino-acid anion
thiosulfates[no description available]medium40divalent inorganic anion;
sulfur oxide;
sulfur oxoanion		human metabolite
cumene[no description available]medium10alkylbenzene
reserpine[no description available]medium30alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic
mercaptoethanol[no description available]medium150alkanethiol;
primary alcohol		geroprotector
chlorpromazine[no description available]medium90organochlorine compound;
phenothiazines;
tertiary amine		anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug
diethylstilbestrol[no description available]medium10olefinic compound;
polyphenol		antifungal agent;
antineoplastic agent;
autophagy inducer;
calcium channel blocker;
carcinogenic agent;
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
endocrine disruptor;
xenoestrogen
methylene blue[no description available]medium10organic chloride saltacid-base indicator;
antidepressant;
antimalarial;
antimicrobial agent;
antioxidant;
cardioprotective agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 4.6.1.2 (guanylate cyclase) inhibitor;
fluorochrome;
histological dye;
neuroprotective agent;
physical tracer
chlorophyll a[no description available]medium10chlorophyll;
methyl ester		cofactor
iodine[no description available]medium10diatomic iodinenutrient
thiophosphoric acid[no description available]medium10phosphorothioic acid
ng-nitroarginine methyl ester[no description available]medium40alpha-amino acid ester;
L-arginine derivative;
methyl ester;
N-nitro compound		EC 1.14.13.39 (nitric oxide synthase) inhibitor
spermine[no description available]medium20polyazaalkane;
tetramine		antioxidant;
fundamental metabolite;
immunosuppressive agent
arginine[no description available]medium50arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
putrescine[no description available]medium10alkane-alpha,omega-diamineantioxidant;
fundamental metabolite
diaminorhodamine-4m[no description available]medium10
2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide[no description available]medium10
urethane[no description available]medium30carbamate esterfungal metabolite;
mutagen
nitrates[no description available]medium30monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species
streptomycin[no description available]medium40antibiotic antifungal drug;
antibiotic fungicide;
streptomycins		antibacterial drug;
antifungal agrochemical;
antimicrobial agent;
antimicrobial drug;
bacterial metabolite;
protein synthesis inhibitor
melphalan[no description available]medium30L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
guanethidine[no description available]medium20azocanes;
guanidines		adrenergic antagonist;
antihypertensive agent;
sympatholytic agent
citric acid, anhydrous[no description available]medium10tricarboxylic acidantimicrobial agent;
chelator;
food acidity regulator;
fundamental metabolite
manganese[no description available]medium10elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
histamine[no description available]medium160aralkylamino compound;
imidazoles		human metabolite;
mouse metabolite;
neurotransmitter
cyclic gmp[no description available]medium203',5'-cyclic purine nucleotide;
guanyl ribonucleotide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
serine[no description available]medium70L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
tiopronin[no description available]medium110N-acyl-amino acid
ethidium[no description available]medium30phenanthridinesfluorochrome;
intercalator
ditiocarb[no description available]medium20dithiocarbamic acidschelator;
copper chelator
metronidazole[no description available]medium10C-nitro compound;
imidazoles;
primary alcohol		antiamoebic agent;
antibacterial drug;
antimicrobial agent;
antiparasitic agent;
antitrichomonal drug;
environmental contaminant;
prodrug;
radiosensitizing agent;
xenobiotic
4-nitroacetophenone[no description available]medium10acetophenones;
C-nitro compound
fluorouracil[no description available]medium20nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
cytarabine[no description available]medium10beta-D-arabinoside;
monosaccharide derivative;
pyrimidine nucleoside		antimetabolite;
antineoplastic agent;
antiviral agent;
immunosuppressive agent
ethylmaleimide[no description available]medium10maleimidesanticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor
nitrofurazone[no description available]medium10
adeturon[no description available]medium320
triaziquone[no description available]medium501,4-benzoquinones;
aziridines		alkylating agent;
antineoplastic agent
sodium fluoride[no description available]medium10fluoride saltmutagen
cysteamine-s-phosphate[no description available]medium80organic phosphorothioate anion
amifostine anhydrous[no description available]medium80diamine;
organic thiophosphate		antioxidant;
prodrug;
radiation protective agent
adenosine diphosphate[no description available]medium50adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite;
human metabolite
adenosine[no description available]medium10adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
tryptophan[no description available]medium20erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
5-hydroxytryptophan[no description available]medium130hydroxytryptophanhuman metabolite;
neurotransmitter
deoxycytidine[no description available]medium10pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
oxyquinoline[no description available]medium20monohydroxyquinolineantibacterial agent;
antifungal agrochemical;
antiseptic drug;
iron chelator
homocysteine[no description available]medium50amino acid zwitterion;
homocysteine;
serine family amino acid		fundamental metabolite;
mouse metabolite
triiodothyronine[no description available]medium20tetrahydrothiophenes;
thiolactone		human metabolite
alpha-chymotrypsin[no description available]medium20
choline[no description available]medium20cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
deuterium[no description available]medium20dihydrogen
glucose, (beta-d)-isomer[no description available]medium10D-glucopyranoseepitope;
mouse metabolite
acetylcysteine[no description available]medium30acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary
chiniofon[no description available]medium10
concanavalin a[no description available]medium30
polonium[no description available]medium10chalcogen;
metal atom
acid phosphatase[no description available]medium60
unithiol[no description available]medium20
wr 1065[no description available]medium20alkanethiol;
diamine		antioxidant;
drug metabolite;
radiation protective agent
hydroxylamine[no description available]medium20hydroxylaminesalgal metabolite;
bacterial xenobiotic metabolite;
EC 1.1.3.13 (alcohol oxidase) inhibitor;
EC 4.2.1.22 (cystathionine beta-synthase) inhibitor;
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor;
nitric oxide donor;
nucleophilic reagent
selenium[no description available]medium40chalcogen;
nonmetal atom		micronutrient
omega-n-methylarginine[no description available]medium30amino acid zwitterion;
arginine derivative;
guanidines;
L-arginine derivative;
non-proteinogenic L-alpha-amino acid
mustard gas[no description available]medium10ethyl sulfide;
organochlorine compound		alkylating agent;
carcinogenic agent;
vesicant
trinitrobenzenesulfonic acid[no description available]medium10arenesulfonic acid;
C-nitro compound		epitope;
explosive;
reagent
interleukin-8[no description available]medium10
endothelin-1[no description available]medium10
nitrites[no description available]medium20monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species		human metabolite
technetium[no description available]medium10manganese group element atom
tin[no description available]medium10carbon group element atom;
elemental tin;
metal atom		micronutrient
peroxynitric acid[no description available]medium10nitrogen oxoacid
2-amino-4-picoline[no description available]medium10
benzo(a)pyrene[no description available]medium10ortho- and peri-fused polycyclic arenecarcinogenic agent;
mouse metabolite
lysine[no description available]medium10aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
etilefrine[no description available]medium10phenols
phenylephrine[no description available]medium40phenols;
phenylethanolamines;
secondary amino compound		alpha-adrenergic agonist;
cardiotonic drug;
mydriatic agent;
nasal decongestant;
protective agent;
sympathomimetic agent;
vasoconstrictor agent
octopamine[no description available]medium10phenylethanolamines;
tyramines		neurotransmitter
dithiothreitol[no description available]medium901,4-dimercaptobutane-2,3-diol;
butanediols;
dithiol;
glycol;
thiol		chelator;
human metabolite;
reducing agent
dehydroascorbic acid[no description available]medium10dehydroascorbic acid;
vitamin C		coenzyme;
mouse metabolite
bromodeoxyuridine[no description available]medium10pyrimidine 2'-deoxyribonucleosideantimetabolite;
antineoplastic agent
rifampin[no description available]medium10cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor
chloramphenicol[no description available]medium40C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor
puromycin[no description available]medium10puromycinsantiinfective agent;
antimicrobial agent;
antineoplastic agent;
EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor;
EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor;
nucleoside antibiotic;
protein synthesis inhibitor
cycloheximide[no description available]medium30antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor
aspartic acid[no description available]medium10aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
methionine[no description available]medium30aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
inosine diphosphate[no description available]medium10inosine phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite
inosine triphosphate[no description available]medium10inosine phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
xanthinol niacinate[no description available]medium10
theophylline[no description available]medium30dimethylxanthineadenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent
methyldopa[no description available]medium20L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		alpha-adrenergic agonist;
antihypertensive agent;
hapten;
peripheral nervous system drug;
sympatholytic agent
bucladesine[no description available]medium103',5'-cyclic purine nucleotide
nad[no description available]medium40organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
3-mercaptopropionic acid[no description available]medium10mercaptopropanoic acidalgal metabolite
glutaral[no description available]medium10dialdehydecross-linking reagent;
disinfectant;
fixative
erythrosine[no description available]medium20
metrizoate[no description available]medium10monocarboxylic acidradioopaque medium
thiotepa[no description available]medium20aziridines
asparagine[no description available]medium20amino acid zwitterion;
asparagine;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
pyridoxal[no description available]medium10hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
iodoacetamide[no description available]medium10
dithioerythritol[no description available]medium101,4-dimercaptobutane-2,3-diolreducing agent
carnosine[no description available]medium10amino acid zwitterion;
dipeptide		anticonvulsant;
antineoplastic agent;
antioxidant;
Daphnia magna metabolite;
geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent
hycanthone[no description available]medium10thioxanthenesmutagen;
schistosomicide drug
dichlorvos[no description available]medium10alkenyl phosphate;
dialkyl phosphate;
organochlorine acaricide;
organophosphate insecticide		anthelminthic drug;
antibacterial agent;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor
mebendazole[no description available]medium10aromatic ketone;
benzimidazoles;
carbamate ester		antinematodal drug;
microtubule-destabilising agent;
tubulin modulator
phenylbutazone[no description available]medium10pyrazolidinesantirheumatic drug;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug
lysergic acid diethylamide[no description available]medium10ergoline alkaloid;
monocarboxylic acid amide;
organic heterotetracyclic compound		dopamine agonist;
hallucinogen;
serotonergic agonist
isoniazid[no description available]medium20carbohydrazideantitubercular agent;
drug allergen
caffeine[no description available]medium30purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic
cyclamic acid[no description available]medium10sulfamic acidsenvironmental contaminant;
human xenobiotic metabolite
phenyl acetate[no description available]medium50benzenes;
phenyl acetates
phosphatidylcholines[no description available]medium101,2-diacyl-sn-glycero-3-phosphocholine
phosphorus radioisotopes[no description available]medium10
clonidine[no description available]medium10clonidine;
imidazoline
isoproterenol[no description available]medium20catechols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent
chloroquine[no description available]medium20aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
glycogen[no description available]medium10
adenosine monophosphate[no description available]medium10adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
ammonium hydroxide[no description available]medium10inorganic hydroxy compoundfood acidity regulator
fluorescein-5-isothiocyanate[no description available]medium10fluorescein isothiocyanate
hydroxyindoleacetic acid[no description available]medium10indole-3-acetic acidsdrug metabolite;
human metabolite;
mouse metabolite
streptovitacin a[no description available]medium10
16,16-dimethylprostaglandin e2[no description available]medium10cyclopentanones;
monocarboxylic acid;
prostanoid;
secondary allylic alcohol		anti-ulcer drug;
gastrointestinal drug;
radiation protective agent
lead[no description available]medium10carbon group element atom;
elemental lead;
metal atom		neurotoxin
cephalothin[no description available]medium10azabicycloalkene;
beta-lactam antibiotic allergen;
carboxylic acid;
cephalosporin;
semisynthetic derivative;
thiophenes		antibacterial drug;
antimicrobial agent
cephalosporin c[no description available]medium10cephalosporinfungal metabolite
methoxsalen[no description available]medium10aromatic ether;
psoralens		antineoplastic agent;
cross-linking reagent;
dermatologic drug;
photosensitizing agent;
plant metabolite
5-methoxypsoralen[no description available]medium105-methoxyfurocoumarin;
organic heterotricyclic compound;
psoralens		hepatoprotective agent;
plant metabolite
niobium[no description available]medium10vanadium group element atom
deferoxamine[no description available]medium10acyclic desferrioxaminebacterial metabolite;
ferroptosis inhibitor;
iron chelator;
siderophore
penicillamine[no description available]medium90non-proteinogenic alpha-amino acid;
penicillamine		antirheumatic drug;
chelator;
copper chelator;
drug allergen
sodium salicylate[no description available]medium10organic molecular entity
cobra cardiotoxin proteins[no description available]medium10
tetradecanoylphorbol acetate[no description available]medium10acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator
5,8,11,14-eicosatetraynoic acid[no description available]medium10long-chain fatty acid
phorbols[no description available]medium10diterpene;
terpenoid fundamental parent
2-amino-5,6-dihydro-4h-1,3-thiazine[no description available]medium10
phentolamine[no description available]medium20imidazoles;
phenols;
substituted aniline;
tertiary amino compound		alpha-adrenergic antagonist;
vasodilator agent
scopolamine hydrobromide[no description available]medium10
propranolol[no description available]medium20naphthalenes;
propanolamine;
secondary amine		anti-arrhythmia drug;
antihypertensive agent;
anxiolytic drug;
beta-adrenergic antagonist;
environmental contaminant;
human blood serum metabolite;
vasodilator agent;
xenobiotic
tetrodotoxin[no description available]medium10azatetracycloalkane;
oxatetracycloalkane;
quinazoline alkaloid		animal metabolite;
bacterial metabolite;
marine metabolite;
neurotoxin;
voltage-gated sodium channel blocker
atropine[no description available]medium50
sepharose[no description available]medium10
sucrose[no description available]medium50glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
dimercaprol[no description available]medium50dithiol;
primary alcohol		chelator
pituitrin[no description available]medium10
gallic acid[no description available]medium50trihydroxybenzoic acidantineoplastic agent;
antioxidant;
apoptosis inducer;
astringent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
geroprotector;
human xenobiotic metabolite;
plant metabolite
rutin[no description available]medium10disaccharide derivative;
quercetin O-glucoside;
rutinoside;
tetrahydroxyflavone		antioxidant;
metabolite
eledoisin[no description available]medium10peptide
angiotensin ii[no description available]medium10amino acid zwitterion;
angiotensin II		human metabolite
bradykinin[no description available]medium10oligopeptidehuman blood serum metabolite;
vasodilator agent
kallidin[no description available]medium10peptide
niacinamide[no description available]medium10pyridine alkaloid;
pyridinecarboxamide;
vitamin B3		anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor
losartan potassium[no description available]medium30
p-dimethylaminoazobenzene[no description available]medium10azobenzenes
hydrazine[no description available]medium30azane;
hydrazines		EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
iproniazid[no description available]medium10carbohydrazide;
pyridines
creatine[no description available]medium10glycine derivative;
guanidines;
zwitterion		geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent;
nutraceutical
taurine[no description available]medium10amino sulfonic acid;
zwitterion		antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite
papaverine[no description available]medium20benzylisoquinoline alkaloid;
dimethoxybenzene;
isoquinolines		antispasmodic drug;
vasodilator agent
pentylenetetrazole[no description available]medium10organic heterobicyclic compound;
organonitrogen heterocyclic compound
nicotine[no description available]medium103-(1-methylpyrrolidin-2-yl)pyridineanxiolytic drug;
biomarker;
immunomodulator;
mitogen;
neurotoxin;
nicotinic acetylcholine receptor agonist;
peripheral nervous system drug;
phytogenic insecticide;
plant metabolite;
psychotropic drug;
teratogenic agent;
xenobiotic
strychnine[no description available]medium20monoterpenoid indole alkaloid;
organic heteroheptacyclic compound		avicide;
cholinergic antagonist;
glycine receptor antagonist;
neurotransmitter agent;
rodenticide
amobarbital[no description available]medium10barbiturates
chloral hydrate[no description available]medium10aldehyde hydrate;
ethanediol;
organochlorine compound		general anaesthetic;
mouse metabolite;
sedative;
xenobiotic
cobalt[no description available]medium10cobalt group element atom;
metal allergen		micronutrient
caseins[no description available]medium10
fibrinogen[no description available]medium10iditolfungal metabolite
piperidines[no description available]medium10
carbonates[no description available]medium10carbon oxoanion
thiram[no description available]medium10organic disulfideantibacterial drug;
antifungal agrochemical;
antiseptic drug
1-propanol[no description available]medium10propan-1-ols;
short-chain primary fatty alcohol		metabolite;
protic solvent
primaquine[no description available]medium10aminoquinoline;
aromatic ether;
N-substituted diamine		antimalarial
pyridoxal phosphate[no description available]medium10methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6 phosphate		coenzyme;
cofactor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
histidine[no description available]medium10amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
pempidine[no description available]medium10piperidines
dibenzylchlorethamine[no description available]medium10
cocaine[no description available]medium10benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid		adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
amphetamine[no description available]medium10primary amine
bromine[no description available]medium20diatomic bromine
argon[no description available]medium10monoatomic argon;
noble gas atom;
p-block element atom		food packaging gas;
neuroprotective agent
pantothenic acid[no description available]medium10pantothenic acid;
vitamin B5		antidote to curare poisoning;
geroprotector;
human blood serum metabolite
orotic acid[no description available]medium10pyrimidinemonocarboxylic acidEscherichia coli metabolite;
metabolite;
mouse metabolite
mevalonic acid[no description available]medium103,5-dihydroxy-3-methylpentanoic acid
ubiquinone[no description available]medium10
deoxyuridine[no description available]medium10pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
methysergide[no description available]medium10ergoline alkaloid
thyroxine[no description available]medium102-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine		antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone
mercury[no description available]medium10elemental mercury;
zinc group element atom		neurotoxin
ammonium hydroxide[no description available]medium10azane;
gas molecular entity;
mononuclear parent hydride		EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant
diphenhydramine[no description available]medium20ether;
tertiary amino compound		anti-allergic agent;
antidyskinesia agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
antitussive;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
oneirogen;
sedative
pilocarpine[no description available]medium10pilocarpineantiglaucoma drug
guanine[no description available]medium102-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
uracil[no description available]medium20pyrimidine nucleobase;
pyrimidone		allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
nialamide[no description available]medium10organonitrogen compound;
organooxygen compound
tyramine[no description available]medium10monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter
carbon monoxide[no description available]medium10carbon oxide;
gas molecular entity;
one-carbon compound		biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent
cortisone[no description available]medium1011-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
glycerol[no description available]medium10alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
muramidase[no description available]medium10
azaguanine[no description available]medium10nucleobase analogue;
triazolopyrimidines		antimetabolite;
antineoplastic agent;
EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor
sodium ethylxanthate[no description available]medium20
fomesafen[no description available]medium10aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-sulfonylcarboxamide;
organofluorine compound;
phenols		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
eye[no description available]medium20
4-methoxyamphetamine[no description available]medium10
ConditionIndicatedRelationship StrengthStudiesTrials
Abdomen, Acute0low10
Abnormalities, Autosome0low230
Abnormalities, Chromosomal0low230
Abnormalities, Chromosome0low230
Abnormalities, Congenital0low10
Absence of Brain, Congenital0low10
Acute Hemolytic Transfusion Reaction0low10
Acute Kidney Failure0low10
Acute Kidney Injury0low10
Acute Kidney Insufficiency0low10
Acute Kidney Tubular Necrosis0low10
Acute Liver Injury, Drug-Induced0low20
Acute Myelogenous Leukemia0low10
Acute Myeloid Leukemia0low10
Acute Myeloid Leukemia with Maturation0low10
Acute Myeloid Leukemia without Maturation0low10
Acute Renal Failure0low10
Acute Renal Injury0low10
Acute Renal Insufficiency0low10
Adenocarcinoma0low30
Adenocarcinoma, Basal Cell0low30
Adenocarcinoma, Granular Cell0low30
Adenocarcinoma, Oxyphilic0low30
Adenocarcinoma, Tubular0low30
Adenoma0low10
Adenoma, Basal Cell0low10
Adenoma, Follicular0low10
Adenoma, Malignant0low30
Adenoma, Microcystic0low10
Adenoma, Monomorphic0low10
Adenoma, Papillary0low10
Adenoma, Trabecular0low10
Adjuvant Arthritis0low10
Adrenal Gland Diseases0low10
Aging0low20
Alcohol Drinking0low20
Alloxan Diabetes0low10
Alopecia0low10
Alopecia Cicatrisata0low10
Alopecia, Androgenetic0low10
Alopecia, Male Pattern0low10
Anaplastic Ependymoma0low10
Androgenetic Alopecia0low10
Androgenic Alopecia0low10
Anemia, Aplastic0low10
Anemia, Fanconi0low10
Anemia, Hypoplastic0low10
Anemia, Splenic0low10
Anencephalia0low10
Anencephalus0low10
Anencephaly0low10
Aneuploid0low10
Aneuploid Cell0low10
Aneuploidy0low10
Angioedema0low10
Angioneurotic Edema0low10
Animal Mammary Carcinoma0low30
ANLL0low10
Anoxemia0low120
Anoxia0low120
Antibody Deficiency Syndrome0low10
Aplastic Anaemia0low10
Aplastic Anemia0low10
Aprosencephaly0low10
Arrhythmia0low20
Arrhythmias, Cardiac0low20
Arrythmia0low20
Arteriosclerosis0low10
Arthritis, Adjuvant0low10
Arthritis, Adjuvant-Induced0low10
Arthritis, Collagen-Induced0low10
Arthritis, Experimental0low10
Ascites0low10
Aseptic Meningitis0low20
Atopic Hypersensitivity0low10
Atrioventricular Nodal Re-Entrant Tachycardia0low10
Atrioventricular Reentrant Tachycardia0low10
Aura0low10
Autosomal Chromosome Disorders0low30
Autosome Abnormalities0low230
Awakening Epilepsy0low10
Baldness0low10
Baldness, Male Pattern0low10
Benign Neoplasms0low180
Benign Neoplasms, Brain0low20
Besnier-Boeck Disease0low10
Besnier-Boeck-Schaumann Syndrome0low10
Birth Defects0low10
Blepharitis0low10
Blood Diseases0low10
Blood Poisoning0low10
Blood Pressure, High0low10
Blood Transfusion-Associated Adverse Reactions0low10
Bloodstream Infection0low10
Body Weight0low150
Boeck Disease0low10
Boeck's Disease0low10
Boeck's Sarcoid0low10
Bone Cancer0low10
Bone Marrow Diseases0low10
Bone Neoplasms0low10
Bovine Diseases0low10
Bradyarrhythmia0low10
Bradyarrhythmias0low10
Bradycardia0low10
Brain Cancer0low20
Brain Metastases0low20
Brain Neoplasm, Primary0low20
Brain Neoplasms0low20
Brain Neoplasms, Benign0low20
Brain Neoplasms, Malignant0low20
Brain Neoplasms, Malignant, Primary0low20
Brain Neoplasms, Primary Malignant0low20
Brain Tumor, Primary0low20
Brain Tumor, Recurrent0low20
Brain Tumors0low20
Breast Cancer0low30
Breast Carcinoma0low30
Breast Neoplasms0low30
Breast Tumors0low30
Bronchial Pneumonia0low10
Bronchopneumonia0low10
Calcification, Pathologic0low10
Calcinosis0low10
Calcinosis, Tumoral0low10
Cancer0low180
Cancer of Bone0low10
Cancer of Brain0low20
Cancer of Breast0low30
Cancer of Gastrointestinal Tract0low10
Cancer of Liver0low10
Cancer of Lung0low50
Cancer of Ovary0low50
Cancer of Pelvis0low10
Cancer of Skin0low30
Cancer of the Bone0low10
Cancer of the Brain0low20
Cancer of the Breast0low30
Cancer of the Gastrointestinal Tract0low10
Cancer of the Liver0low10
Cancer of the Lung0low50
Cancer of the Ovary0low50
Cancer of the Pelvis0low10
Cancer of the Skin0low30
Cancer of the Thymus0low10
Cancer of Thymus0low10
Cancer, Hepatocellular0low10
Cancer, Radiation-Induced0low110
Canine Diseases0low10
Carbon Tetrachloride Poisoning0low10
Carcinoma0low60
Carcinoma 256, Walker0low30
Carcinoma, Anaplastic0low60
Carcinoma, Cribriform0low30
Carcinoma, Ehrlich Tumor0low140
Carcinoma, Epidermoid0low10
Carcinoma, Granular Cell0low30
Carcinoma, Hepatocellular0low10
Carcinoma, Krebs 20low10
Carcinoma, Planocellular0low10
Carcinoma, Spindle-Cell0low60
Carcinoma, Squamous0low10
Carcinoma, Squamous Cell0low10
Carcinoma, Tubular0low30
Carcinoma, Undifferentiated0low60
Carcinomatosis0low60
Carcinosarcoma 256, Walker0low30
Cardiac Arrhythmia0low20
Cardiac Arrhythmias0low20
Cardiac Death0low10
Cardiac Dysrhythmia0low20
Cardiovascular Diseases0low20
Cataract0low50
Cataract, Membranous0low50
Cattle Diseases0low10
CCl4 Poisoning0low10
Cellular Ependymoma0low10
Central Hypothyroidism0low10
Chemical and Drug Induced Liver Injury0low20
Chemically-Induced Liver Toxicity0low20
Chest Injuries0low10
Chromosomal Aberrations0low230
Chromosomal Disorders0low30
Chromosomal Translocation0low60
Chromosome Aberrations0low230
Chromosome Abnormalities0low230
Chromosome Abnormality Disorders0low30
Chromosome Disorders0low30
Chromosome-Defective Micronuclei0low20
Chronic Disease0low10
Chronic Illness0low10
Chronically Ill0low10
Cicatrix0low10
Cicatrization0low10
Cirrhosis, Liver0low10
Clear Cell Ependymoma0low10
Collagen Arthritis0low10
Coma0low10
Comatose0low10
Complications, Pregnancy0low10
Congenital Abnormalities0low10
Congenital Absence of Brain0low10
Congenital Defects0low10
Congenital Thrombotic Thrombocytopenic Purpura0low10
Congenital Zika Syndrome0low10
Congenital Zika Virus Infection0low10
Conjunctivitis0low10
Contact Dermatitis0low20
Coronary Disease0low10
Coronary Heart Disease0low10
Curling Ulcer0low10
Curling's Ulcer0low10
Cytogenetic Aberrations0low230
Cytogenetic Abnormalities0low230
Death0low10
Defects, Congenital0low10
Deficiency Syndrome, Immunologic0low10
Deficiency Syndromes, Antibody0low10
Deficiency Syndromes, Immunologic0low10
Deficiency, Oxygen0low120
Deformities0low10
Delayed Effects, Prenatal Exposure0low10
Delayed Hemolytic Transfusion Reaction0low10
Delayed Hypersensitivity0low20
Delayed Serologic Transfusion Reaction0low10
Delusional Disorder0low10
Depression0low10
Depression, Endogenous0low10
Depression, Neurotic0low10
Depression, Unipolar0low10
Depressive Disorder0low10
Depressive Syndrome0low10
Dermatitis Exfoliativa0low10
Dermatitis Exfoliative0low10
Dermatitis Exfoliative Generalised0low10
Dermatitis Exfoliative Generalized0low10
Dermatitis Venenata0low20
Dermatitis, Contact0low20
Dermatitis, Exfoliative0low10
Dermatitis, Radiation-Induced0low10
Determination of Death0low10
Diabetes Mellitus, Experimental0low10
Diffuse Mixed Small and Large Cell Lymphoma0low20
Diffuse Mixed-Cell Lymphoma0low20
Diffuse Small Cleaved-Cell Lymphoma0low20
Diffuse Undifferentiated Lymphoma0low20
Disease Models, Animal0low40
Dog Diseases0low10
Drug-Induced Acute Liver Injury0low20
Drug-Induced Liver Disease0low20
Drug-Induced Liver Injury0low20
Duodenal Ulcer0low10
Dwarfism0low20
E coli Infections0low10
E. coli Infection0low10
Eczema, Contact0low20
Ehrlich Ascites Tumor0low140
EHS Tumor0low60
End Of Life0low10
End-Of-Life0low10
Endotoxemia0low60
Enlarged Spleen0low10
Ependymoma0low10
Ependymoma, Myxopapillary0low10
Ependymoma, Papillary0low10
Epilepsy0low10
Epilepsy, Cryptogenic0low10
Epithelial Neoplasms, Malignant0low60
Epithelial Tumors, Malignant0low60
Epithelioma0low60
Erythrocytosis0low20
Erythroderma0low10
Escherichia coli Infections0low10
Experimental Diabetes Mellitus0low10
Experimental Leukemia0low50
Experimental Leukemias0low50
Experimental Lung Inflammation0low10
Experimental Mammary Neoplasms0low60
Experimental Neoplasms0low190
Experimental Radiation Injuries0low1250
Experimental Sarcoma0low60
Experimental Sarcomas0low60
Extravascular Hemolysis0low230
Eye Diseases0low10
Eye Disorders0low10
Familial Thrombotic Thrombocytopenia Purpura0low10
Familial Thrombotic Thrombocytopenic Purpura0low10
Fanconi Anemia0low10
Fanconi Hypoplastic Anemia0low10
Fanconi Pancytopenia0low10
Fanconi Panmyelopathy0low10
Fanconi's Anemia0low10
Fatigue0low10
Fatty Liver0low10
Febrile Non-Hemolytic Transfusion Reaction0low10
Female Pattern Baldness0low10
Fetal Anomalies0low10
Fetal Death0low20
Fetal Demise0low20
Fetal Malformations0low10
Fetal Mummification0low20
Fetal Resorption0low40
Fever, Zika0low10
Fibrosis, Liver0low10
Gastrointestinal Cancer0low10
Gastrointestinal Neoplasms0low10
Genotoxicant-Induced Micronuclei0low20
Germinoblastoma0low60
Giant Cell Tumors0low10
Glandular Fever0low20
Haemolysis0low230
Hair Loss0low10
Heart Disease, Ischemic0low10
Hematologic Diseases0low10
Hematological Diseases0low10
Hematuria0low10
Hemicranial Anencephaly0low10
Hemoglobinuria0low10
Hemoglobinuria, Paroxysmal0low210
Hemolysis0low230
Hemolytic Transfusion Reaction0low10
Hepatic Cancer0low10
Hepatic Cirrhosis0low10
Hepatic Neoplasms0low10
Hepatitis B0low10
Hepatitis B Virus Infection0low10
Hepatitis, Drug-Induced0low20
Hepatitis, Toxic0low20
Hepatocellular Cancer0low10
Hepatocellular Carcinoma0low10
Hepatoma0low10
Human Mammary Carcinoma0low30
Hyaline Membrane Disease0low10
Hypersensitivity, Atopic0low10
Hypersensitivity, Contact0low20
Hypersensitivity, Delayed0low20
Hypersensitivity, Immediate0low10
Hypersensitivity, Tuberculin-Type0low20
Hypersensitivity, Type I0low10
Hypersensitivity, Type IV0low20
Hypersplenism0low10
Hypertension0low10
Hyperthyroid0low10
Hyperthyroidism0low10
Hypotensive Transfusion Reaction0low10
Hypothermia0low10
Hypothermia, Accidental0low10
Hypothyroidism0low10
Hypoxemia0low120
Hypoxia0low120
Idiopathic Ventricular Tachycardia0low10
IgE-Mediated Hypersensitivity0low10
Immunologic Deficiency Syndrome0low10
Immunologic Deficiency Syndromes0low10
Immunological Deficiency Syndromes0low10
Incomplete Anencephaly0low10
Infection0low10
Infection and Infestation0low10
Infections0low10
Infections and Infestations0low10
Infections, E coli0low10
Infections, Escherichia coli0low10
Infectious Mononucleosis0low20
Infertility0low10
Infertility, Male0low20
Inflammation0low10
Injuries, Chest0low10
Injuries, Experimental Radiation0low1250
Injuries, Radiation0low510
Injuries, Thoracic0low10
Injury, Ischemia-Reperfusion0low10
Injury, Myocardial Reperfusion0low10
Injury, Reperfusion0low10
Innate Inflammatory Response0low10
Intestinal Diseases0low30
Intestinal Perforation0low10
Intracranial Neoplasms0low20
Intravascular Hemolysis0low230
Ischemia0low10
Ischemia-Reperfusion Injury0low10
Ischemia, Myocardial0low10
Ischemic Heart Disease0low10
Itching0low10
Kidney Diseases0low30
Kidney Failure, Acute0low10
Kidney Insufficiency, Acute0low10
Kidney Tubular Necrosis, Acute0low10
Lassitude0low10
Late Effects, Prenatal Exposure0low10
Lens Opacities0low50
Leucocythaemia0low60
Leucocythemia0low60
Leukemia0low60
Leukemia Model, Animal0low50
Leukemia, Acute Myelogenous0low10
Leukemia, Acute Myeloid0low10
Leukemia, Experimental0low50
Leukemia, Lymphocytic0low50
Leukemia, Lymphoid0low50
Leukemia, Myeloblastic, Acute0low10
Leukemia, Myelocytic, Acute0low10
Leukemia, Myelogenous, Acute0low10
Leukemia, Myeloid, Acute0low10
Leukemia, Myeloid, Acute, M10low10
Leukemia, Myeloid, Acute, M20low10
Leukemia, Nonlymphoblastic, Acute0low10
Leukemia, Nonlymphocytic, Acute0low10
Leukemia, Radiation-Induced0low20
Leukemias, Experimental0low50
Leukocytopenia0low20
Leukopenia0low20
Libman-Sacks Disease0low20
Liver Cancer0low10
Liver Cancer, Adult0low10
Liver Cell Carcinoma0low10
Liver Cell Carcinoma, Adult0low10
Liver Cirrhosis0low10
Liver Diseases0low20
Liver Dysfunction0low20
Liver Fibrosis0low10
Liver Injury, Drug-Induced0low20
Liver Injury, Drug-Induced, Acute0low20
Liver Neoplasms0low10
Liver Steatosis0low10
Lobar Pneumonia0low10
Lower Nephron Nephrosis0low10
Lung Cancer0low50
Lung Inflammation0low10
Lung Neoplasms0low50
Lupus Erythematosus Disseminatus0low20
Lupus Erythematosus, Systemic0low20
Lymphatic Diseases0low10
Lymphatic Sarcoma0low20
Lymphatism0low10
Lymphocytic Leukemia0low50
Lymphoid Leukemia0low50
Lymphoma0low60
Lymphoma, Atypical Diffuse Small Lymphoid0low20
Lymphoma, Diffuse0low20
Lymphoma, Diffuse, Mixed Lymphocytic-Histiocytic0low20
Lymphoma, High-Grade0low20
Lymphoma, Intermediate-Grade0low20
Lymphoma, Low-Grade0low20
Lymphoma, Malignant0low60
Lymphoma, Mixed0low20
Lymphoma, Mixed Cell, Diffuse0low20
Lymphoma, Mixed Lymphocytic-Histiocytic0low20
Lymphoma, Mixed Small and Large Cell, Diffuse0low20
Lymphoma, Mixed-Cell0low20
Lymphoma, Mixed-Cell, Diffuse0low20
Lymphoma, Non-Hodgkin0low20
Lymphoma, Non-Hodgkin, Familial0low20
Lymphoma, Non-Hodgkin's0low20
Lymphoma, Non-Hodgkins0low20
Lymphoma, Nonhodgkin's0low20
Lymphoma, Nonhodgkins0low20
Lymphoma, Pleomorphic0low20
Lymphoma, Small and Large Cleaved-Cell, Diffuse0low20
Lymphoma, Small Cleaved Cell, Diffuse0low20
Lymphoma, Small Cleaved-Cell, Diffuse0low20
Lymphoma, Small Non-Cleaved-Cell0low20
Lymphoma, Small Noncleaved-Cell0low20
Lymphoma, Undifferentiated0low20
Lymphoma, Undifferentiated, Diffuse0low20
Lymphosarcoma0low20
Male Pattern Baldness0low10
Malignancy0low180
Malignant Epithelial Neoplasms0low60
Malignant Melanoma0low20
Malignant Neoplasm of Breast0low30
Malignant Neoplasms0low180
Malignant Neoplasms, Brain0low20
Malignant Primary Brain Neoplasms0low20
Malignant Primary Brain Tumors0low20
Malignant Tumor of Breast0low30
Mammary Cancer0low30
Mammary Carcinoma, Animal0low30
Mammary Carcinoma, Human0low30
Mammary Neoplasm, Human0low30
Mammary Neoplasms0low30
Mammary Neoplasms, Animal0low30
Mammary Neoplasms, Experimental0low60
Mammary Neoplasms, Human0low30
Marchiafava-Micheli Syndrome0low210
Melancholia0low10
Melanoma0low20
Meningitis, Aseptic0low20
Metastase0low10
Metastases, Neoplasm0low10
Metastasis0low10
Metastasis, Neoplasm0low10
Methemoglobinemia0low10
Microangiopathic Hemolytic Anemia, Congenital0low10
Microcalcification0low10
Microcalcinosis0low10
Microcephaly0low10
Microlissencephaly0low10
Micronuclei, Chromosome-Defective0low20
Micronuclei, Genotoxicant-Induced0low20
Micronucleus, Chromosome-Defective0low20
Mixed Small and Large Cell Lymphoma, Diffuse0low20
Mixed-Cell Lymphoma0low20
Mixed-Cell Lymphoma, Diffuse0low20
MODS0low20
Mononucleosis, Infectious0low20
Moschcowitz Disease0low10
Moschkowitz Disease0low10
MS (Multiple Sclerosis)0low40
Multiple Organ Dysfunction Syndrome0low20
Multiple Organ Failure0low20
Multiple Sclerosis0low40
Multiple Sclerosis, Acute Fulminating0low40
Muscle Contraction0low30
Mycosis Fungoides0low10
Myeloblastic Leukemia, Acute0low10
Myelocytic Leukemia, Acute0low10
Myelogenous Leukemia, Acute0low10
Myeloid Leukemia, Acute0low10
Myeloid Leukemia, Acute, M10low10
Myeloid Leukemia, Acute, M20low10
Myocardial Ischemia0low10
Myocardial Ischemic Reperfusion Injury0low10
Myocardial Reperfusion Injury0low10
Nanism0low20
Near-Death Experience0low10
Necrosis0low10
Necrotizing Pyelonephritis0low10
Neoplasia0low180
Neoplasm0low180
Neoplasm Metastases0low10
Neoplasm Metastasis0low10
Neoplasms0low180
Neoplasms of Pelvis0low10
Neoplasms, Benign0low180
Neoplasms, Bone0low10
Neoplasms, Brain0low20
Neoplasms, Brain, Benign0low20
Neoplasms, Brain, Malignant0low20
Neoplasms, Brain, Primary0low20
Neoplasms, Breast0low30
Neoplasms, Experimental0low190
Neoplasms, Experimental Mammary0low60
Neoplasms, Gastrointestinal0low10
Neoplasms, Hepatic0low10
Neoplasms, Intracranial0low20
Neoplasms, Liver0low10
Neoplasms, Lung0low50
Neoplasms, Malignant Epithelial0low60
Neoplasms, Mammary0low30
Neoplasms, Ovarian0low50
Neoplasms, Pulmonary0low50
Neoplasms, Radiation-Induced0low110
Neoplasms, Skin0low30
Neoplasms, Thymic0low10
Neoplasms, Thymus0low10
Nephrosclerosis0low30
Nephrosis0low10
Neurosis, Depressive0low10
Non-Hodgkin Lymphoma0low20
Non-Hodgkin's Lymphoma0low20
Nonlymphoblastic Leukemia, Acute0low10
Nonlymphocytic Leukemia, Acute0low10
Nonsustained Ventricular Tachycardia0low10
Orbital Neoplasms0low10
Organ Dysfunction Syndrome, Multiple0low20
Organ Failure, Multiple0low20
Osteosclerosis0low10
Ovarian Cancer0low50
Ovarian Neoplasms0low50
Ovary Cancer0low50
Ovary Neoplasms0low50
Oxygen Deficiency0low120
Papillary Ependymoma0low10
Paranoid Schizophrenia0low10
Paroxysmal Cold Hemoglobinuria0low210
Paroxysmal Hemoglobinuria0low210
Paroxysmal Hemoglobinuria, Cold0low210
Paroxysmal Hemoglobinuria, Nocturnal0low210
Paroxysmal Nocturnal Hemoglobinuria0low210
Paroxysmal Supraventricular Tachycardia0low10
Partial Anencephaly0low10
Pathologic Calcification0low10
Pattern Baldness0low10
Pelvic Cancer0low10
Pelvic Neoplasms0low10
Pelvis Cancer0low10
Pelvis Neoplasms0low10
Pink Eye0low10
Plasma Cell Tumor0low10
Plasmacytoma0low10
Plasmocytoma0low10
Pneumonia0low10
Pneumonia, Lobar0low10
Pneumonitis0low10
Poisoning0low10
Poisoning, Blood0low10
Poisoning, Carbon Tetrachloride0low10
Poisoning, CCl40low10
Polycythemia0low20
Post-Transfusion Purpura0low10
Posttransfusion Purpura0low10
Pregnancy0low140
Pregnancy Complications0low10
Prenatal Exposure Delayed Effects0low10
Primary Brain Neoplasms0low20
Primary Hyperthyroidism0low10
Primary Hypothyroidism0low10
Primary Malignant Brain Neoplasms0low20
Primary Malignant Brain Tumors0low20
Pruritis0low10
Pruritus0low10
Pseudoaphakia0low50
Pseudocoma0low10
Pseudopelade0low10
Pulmonary Cancer0low50
Pulmonary Inflammation0low10
Pulmonary Neoplasms0low50
Purpura, Thrombotic Thrombocytopenic0low10
Purpura, Thrombotic Thrombopenic0low10
Pyaemia0low10
Pyelonephritis0low10
Pyelonephritis, Acute Necrotizing0low10
Pyemia0low10
Pyohemia0low10
Quincke's Edema0low10
Radiation Injuries0low510
Radiation Injuries, Experimental0low1250
Radiation Recall Dermatitis0low10
Radiation Recall Reaction0low10
Radiation Sickness0low510
Radiation Syndrome0low510
Radiation-Induced Cancer0low110
Radiation-Induced Dermatitis0low10
Radiation-Induced Leukemia0low20
Radiation-Induced Neoplasms0low110
Radiodermatitis0low10
Renal Failure, Acute0low10
Renal Insufficiency, Acute0low10
Reperfusion Damage0low10
Reperfusion Injury0low10
Reperfusion Injury, Myocardial0low10
Reproductive Sterility0low10
Respiratory Tract Diseases0low10
Reticulolymphosarcoma0low60
Reticulosarcoma0low20
Reticulum Cell Sarcoma0low20
Reticulum Cell-Like Sarcoma, Yoshida0low10
Reticulum-Cell Sarcoma0low20
Salpingitis0low10
Sarcoidosis0low10
Sarcoma0low40
Sarcoma 1800low20
Sarcoma 180, Crocker0low20
Sarcoma 370low20
Sarcoma, Engelbreth-Holm-Swarm0low60
Sarcoma, Epithelioid0low40
Sarcoma, Experimental0low60
Sarcoma, Germinoblastic0low60
Sarcoma, Jensen0low60
Sarcoma, Lymphatic0low20
Sarcoma, Reticulum-Cell0low20
Sarcoma, Soft Tissue0low40
Sarcoma, Spindle Cell0low40
Sarcoma, Yoshida0low10
Sarcomas, Experimental0low60
Scar0low10
Scarring0low10
Scars0low10
Schaumann Disease0low10
Schaumann Syndrome0low10
Schaumann's Syndrome0low10
Schizophrenia, Paranoid0low10
Schulman-Upshaw Syndrome0low10
Sclerosis0low10
Sclerosis, Disseminated0low40
Secondary Hypothyroidism0low10
Seizure Disorder0low10
Sensitivity, Contact0low20
Sepsis0low10
Septicemia0low10
Severe Congenital Microcephaly0low10
Severe Sepsis0low10
Skin Cancer0low30
Skin Neoplasms0low30
Small Cleaved-Cell Lymphoma, Diffuse0low20
Small Non-Cleaved-Cell Lymphoma0low20
Small Noncleaved-Cell Lymphoma0low20
Splenomegaly0low10
Squamous Cell Carcinoma0low10
Status Lymphaticus0low10
Steatohepatitis0low10
Steatosis of Liver0low10
Sterility0low10
Sterility, Male0low20
Sterility, Reproductive0low10
Streptozocin Diabetes0low10
Streptozotocin Diabetes0low10
Sub-Fertility0low10
Sub-Fertility, Male0low20
Subfertility0low10
Subfertility, Male0low20
Symptom Cluster0low10
Syndrome0low10
Systemic Lupus Erythematosus0low20
Tachycardia, Ventricular0low10
TAGHD0low10
Testicular Diseases0low10
Thoracic Injuries0low10
Thrombocytopenia0low10
Thrombopenia0low10
Thrombotic Microangiopathy, Familial0low10
Thrombotic Thrombocytopenic Purpura0low10
Thrombotic Thrombocytopenic Purpura, Congenital0low10
Thrombotic Thrombocytopenic Purpura, Familial0low10
Thymic Cancer0low10
Thymic Neoplasms0low10
Thymic Tumors0low10
Thymus Cancer0low10
Thymus Neoplasms0low10
Thymus Tumors0low10
Thyroid-Stimulating Hormone Deficiency0low10
Toxic Hepatitis0low20
Transfusion Reaction0low10
Transfusion-Associated Allergic Reaction0low10
Transfusion-Associated Circulatory Overload0low10
Transfusion-Associated Dyspnea0low10
Transfusion-Associated Graft Vs. Host Disease0low10
Transfusion-Transmitted Infection0low10
Translocation, Chromosomal0low60
Translocation, Genetic0low60
TSH Deficiency0low10
Tuberculin-Type Hypersensitivity0low20
Tumors0low180
Tumors, Breast0low30
Type I Hypersensitivity0low10
Type IV Hypersensitivity0low20
Undifferentiated Lymphoma0low20
Unipolar Depression0low10
Upshaw Factor, Deficiency of0low10
Upshaw-Schulman Syndrome0low10
Urticaria, Giant0low10
Ventricular Fibrillation0low10
Ventricular Tachyarrhythmias0low10
Ventricular Tachycardia0low10
Visceral Steatosis0low10
Water-Electrolyte Imbalance0low10
Zika Fever0low10
Zika Virus Disease0low10
Zika Virus Infection0low10
ZikV Infection0low10

Research Highlights

Safety/Toxicity (4)

ArticleYear
Radioprotective and toxic effects of a mixture of AET and 5-methoxytryptamine in mice.
Physiologia Bohemoslovaca, Volume: 24, Issue: 2		1975
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (2)

ArticleYear
The cellular nature of concanavalin A-stimulated antibody-dependent cell-mediated cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950), Volume: 124, Issue: 4		1980
[Immune response in mice exposed to low-dose X-rays].
Comptes rendus des seances de la Societe de biologie et de ses filiales, Volume: 183, Issue: 6		1989
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]