lactic acid has been researched along with Hypertension in 97 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Therefore, we carried out a randomized, double-blind study to compare the effects of losartan (50 mg QD) and metoprolol (95 mg QD) on insulin sensitivity, insulin secretion, glucose tolerance, and lipids and lipoproteins in 20 hyperinsulinemic subjects with essential hypertension." | 9.08 | Effects of losartan on insulin sensitivity in hypertensive subjects. ( Karjalainen, L; Laakso, M; Lempiäinen-Kuosa, P, 1996) |
| "The relationship between plasma uridine levels and blood pressure (BP), and indicators of muscular purine degradation and insulin resistance (IR) has been evaluated in hypertensive (HT) patients." | 7.74 | Plasma levels of uridine correlate with blood pressure and indicators of myogenic purine degradation and insulin resistance in hypertensive patients. ( Hamada, T; Hisatome, I; Igawa, O; Inokuchi, T; Kaetsu, Y; Kato, M; Mizuta, E; Ninomiya, H; Ohtahara, A; Shigemasa, C; Shimada, T; Sonoyama, K; Sugihara, S; Yamamoto, T; Yamamoto, Y; Yanagihara, K, 2007) |
| "We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model." | 7.73 | Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005) |
| "Moxonidine is a new centrally active imidazoline-receptor agonist being effectively applied in the treatment of arterial hypertension due to its sympathicolytic potency." | 7.71 | [Effect of the imidazoline receptor agonist moxonidine on hemodynamics, coronary circulation, metabolic ischemia markers and the neurohumoral system in patients with essential hypertension. Effects of moxonidine on coronary circulation]. ( Hamel, M; Hamm, C; Miric, M; Mitrovic, V; Thormann, J, 2001) |
| "Insulin, glucagon, glucose, nonesterified fatty acids (NEFA), and lactate response to oral glucose tolerance test (OGTT, 75 g glucose) and their correlation with mean blood pressure (BP), were studied in 10 normal subjects (N), 25 subjects with abdominal obesity (O), and 9 subjects with abdominal obesity and IGT or non-insulin-dependent diabetes (OD)." | 7.70 | Response of insulin, glucagon, lactate, and nonesterified fatty acids to glucose in visceral obesity with and without NIDDM: relationship to hypertension. ( Belfiore, F; Campione, R; Iannello, S, 1998) |
| "A 71 year old hypertensive, non insulin-dependent diabetic patient with moderate renal insufficiency taking 500 mg/d of metformin and 5 mg/d of enalapril, developed metabolic acidosis characterized by fairly elevated anion gap, hyperchloremia, severe hyperkaliemia, normal plasma level of 3-hydroxybutyric acid, absence of ketonuria and high plasma level of lactic acid." | 7.69 | Possible synergistic effect of metformin and enalapril on the development of hyperkaliemic lactic acidosis. ( Elisabetta, Z; Emanuela, M; Franzetti, I; Marco, G; Paolo, D; Renato, U, 1997) |
| "The effect of isoflurane on regional myocardial metabolism and blood flow, when used as an adjunct to fentanyl-nitrous oxide anesthesia, to control intraoperative hypertension was investigated." | 7.67 | Control of intraoperative hypertension with isoflurane in patients with coronary artery disease: effects on regional myocardial blood flow and metabolism. ( Appelgren, L; Milocco, I; Ricksten, SE; Sahlman, L; William-Olsson, G, 1989) |
| "This study evaluated the effect of prazosin in controlled mild hypertension and evaluated select metabolic changes that occurred with prazosin monotherapy." | 7.67 | Effect of prazosin treatment on carbohydrate and lipoprotein metabolism in patients with hypertension. ( Chen, YD; Hoffman, BB; Reaven, GM; Sheu, WH; Swislocki, AL, 1989) |
| "Patients with hypertension have a high incidence of coronary artery disease." | 5.27 | Acute effects of captopril on the coronary circulation of patients with hypertension and angina. ( Burgess, JH; Cousineau, D; Daly, P; Rouleau, JL, 1984) |
| " Therefore, we carried out a randomized, double-blind study to compare the effects of losartan (50 mg QD) and metoprolol (95 mg QD) on insulin sensitivity, insulin secretion, glucose tolerance, and lipids and lipoproteins in 20 hyperinsulinemic subjects with essential hypertension." | 5.08 | Effects of losartan on insulin sensitivity in hypertensive subjects. ( Karjalainen, L; Laakso, M; Lempiäinen-Kuosa, P, 1996) |
| "In a single-blind, randomized study, the cardiovascular and metabolic effects of sotalol, 40 to 160 mg/day, in six patients with mild essential hypertension were compared to those of placebo at rest and during submaximal dynamic exercise." | 5.05 | Therapeutic and metabolic effects of sotalol. ( Eliasson, K; Frisk Holmberg, M; Hylander, B; Juhlin Dannfelt, A; Kaiser, P; Rössner, S, 1984) |
| "Increased levels of lactic acid, pyruvate, and TMAO may be related to the pathophysiological changes in the minor ischaemic stroke population." | 4.12 | Related factors based on non-targeted metabolomics methods in minor ischaemic stroke. ( Chen, C; Ding, L; Guo, J; Liu, H; Ma, Y; Qiao, X; Wang, J; Wang, M; Yang, T; Zhao, S, 2022) |
| "The relationship between plasma uridine levels and blood pressure (BP), and indicators of muscular purine degradation and insulin resistance (IR) has been evaluated in hypertensive (HT) patients." | 3.74 | Plasma levels of uridine correlate with blood pressure and indicators of myogenic purine degradation and insulin resistance in hypertensive patients. ( Hamada, T; Hisatome, I; Igawa, O; Inokuchi, T; Kaetsu, Y; Kato, M; Mizuta, E; Ninomiya, H; Ohtahara, A; Shigemasa, C; Shimada, T; Sonoyama, K; Sugihara, S; Yamamoto, T; Yamamoto, Y; Yanagihara, K, 2007) |
| "We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model." | 3.73 | Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005) |
| "Moxonidine is a new centrally active imidazoline-receptor agonist being effectively applied in the treatment of arterial hypertension due to its sympathicolytic potency." | 3.71 | [Effect of the imidazoline receptor agonist moxonidine on hemodynamics, coronary circulation, metabolic ischemia markers and the neurohumoral system in patients with essential hypertension. Effects of moxonidine on coronary circulation]. ( Hamel, M; Hamm, C; Miric, M; Mitrovic, V; Thormann, J, 2001) |
| " Captopril treatment, which reduces maternal blood pressure, during pregnancy and lactation, is reported to have a beneficial effect postnatally, normalizing the blood pressure of offspring in the SHR." | 3.70 | Effects of maternal captopril treatment on growth, blood glucose and plasma insulin in the fetal spontaneously hypertensive rat. ( Bassett, NS; Batchelor, DC; Johnston, BM; Lewis, RM; Skinner, SJ; Vickers, MH, 1999) |
| "Insulin, glucagon, glucose, nonesterified fatty acids (NEFA), and lactate response to oral glucose tolerance test (OGTT, 75 g glucose) and their correlation with mean blood pressure (BP), were studied in 10 normal subjects (N), 25 subjects with abdominal obesity (O), and 9 subjects with abdominal obesity and IGT or non-insulin-dependent diabetes (OD)." | 3.70 | Response of insulin, glucagon, lactate, and nonesterified fatty acids to glucose in visceral obesity with and without NIDDM: relationship to hypertension. ( Belfiore, F; Campione, R; Iannello, S, 1998) |
| "A 71 year old hypertensive, non insulin-dependent diabetic patient with moderate renal insufficiency taking 500 mg/d of metformin and 5 mg/d of enalapril, developed metabolic acidosis characterized by fairly elevated anion gap, hyperchloremia, severe hyperkaliemia, normal plasma level of 3-hydroxybutyric acid, absence of ketonuria and high plasma level of lactic acid." | 3.69 | Possible synergistic effect of metformin and enalapril on the development of hyperkaliemic lactic acidosis. ( Elisabetta, Z; Emanuela, M; Franzetti, I; Marco, G; Paolo, D; Renato, U, 1997) |
| "The effect of isoflurane on regional myocardial metabolism and blood flow, when used as an adjunct to fentanyl-nitrous oxide anesthesia, to control intraoperative hypertension was investigated." | 3.67 | Control of intraoperative hypertension with isoflurane in patients with coronary artery disease: effects on regional myocardial blood flow and metabolism. ( Appelgren, L; Milocco, I; Ricksten, SE; Sahlman, L; William-Olsson, G, 1989) |
| " The prior treatment of hypertension was achieved by administration of hydroflumethiazide (120 mg/kg/day) and captopril (15-30 mg/kg/day) orally for 4-6 weeks by mixing in drinking water." | 3.67 | [Effect of long-term prior antihypertensive treatment on cerebral ischemia induced by bilateral common carotid artery ligation in SHRSR]. ( Inamura, K; Katayama, Y; Nagazumi, A; Shimizu, J; Soeda, T; Sugimoto, S; Suzuki, S; Terashi, A, 1986) |
| "This study evaluated the effect of prazosin in controlled mild hypertension and evaluated select metabolic changes that occurred with prazosin monotherapy." | 3.67 | Effect of prazosin treatment on carbohydrate and lipoprotein metabolism in patients with hypertension. ( Chen, YD; Hoffman, BB; Reaven, GM; Sheu, WH; Swislocki, AL, 1989) |
| "Cerebral blood flow (CBF, by laser Doppler flowmetry) and extracellular cortical concentrations (by microdialysis) of adenosine, inosine, xanthine, hypoxanthine, and lactate were measured together with somatosensory evoked potentials (SEP) in chloralose-anaesthetized spontaneously hypertensive rats (SHR) during relative cerebral ischemia induced by hypotensive hemorrhage." | 3.67 | Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites. ( Carlsson, S; Hagberg, H; Sandberg, M; Skarphedinsson, JO; Thorén, P, 1989) |
| " A diagnosis of idiopathic lactic acidosis was established when the arterial blood pH was found to be 6." | 3.64 | THE CLINICAL SIGNIFICANCE OF ELEVATED BLOOD LACTATE. ( PHILLIPSON, EA; SPROULE, BJ, 1965) |
| " Although the accurate mechanisms are not fully understood; however, some mechanisms, such as sustained release forms with increased bioavailability, increasing oral bioavailability and improving the oral and non-oral absorption, counteracting excessive superoxide and decreasing blood pressure, etc." | 2.82 | The High Potency of Polymeric Nanoparticles in the Drug Delivery System for Hypertension Treatment: A Systematic Review. ( Amin, A; Kiani, A; Mohammadipour, F, 2022) |
| "In order to examine the influence of autonomic dysreflexia on plasma catecholamines, cardiocirculatory and metabolic parameters, 6 spinal cord injured wheelchair athletes with high-level lesions underwent wheelchair ergometry without (ST1) and with (ST2) autonomic dysreflexia." | 2.70 | Catecholamines response of high performance wheelchair athletes at rest and during exercise with autonomic dysreflexia. ( Brunner, C; Eisenbarth, I; Huonker, M; Keul, J; König, D; Lehmann, M; Sauerwein, H; Schmid, A; Schmidt-Trucksäss, A; Storch, MJ, 2001) |
| "Hyperlactatemia is a common complication in critically ill patients with high morbidity and mortality." | 1.72 | Characteristics and predictors of ICU-mortality in critically ill patients with hyperlactatemia requiring CRRT: A retrospective cohort study. ( Bai, M; Li, L; Sun, S; Zhang, Q, 2022) |
| "Respiratory failure was the most frequently observed complication (106 [67." | 1.62 | Identification of risk factors for in-hospital death of COVID - 19 pneumonia -- lessions from the early outbreak. ( Wang, Z, 2021) |
| "Status epilepticus was evoked in half of the sedentary and trained rats by a repetitive intraperitoneal injection of KA in low subconvulsive doses." | 1.46 | Effect of Training at Lactate Threshold Intensity on Maximal Time to Exhaustion, Depression and Anxiety Behaviour of Spontaneously Hypertensive Rats after Kainate-Induced Status Epilepticus. ( Andreev, GG; Georgiev, NG; Georgieva, KN; Hadjieva, MS; Shishmanova-Doseva, MS; Tchekalarova, JD; Terzieva, DD, 2017) |
| "Systemic arterial hypertension has been previously suggested to develop as a compensatory condition when central nervous perfusion/oxygenation is compromised." | 1.42 | Brainstem hypoxia contributes to the development of hypertension in the spontaneously hypertensive rat. ( Ang, R; Gourine, AV; Hosford, PS; Karagiannis, A; Kasparov, S; Kasymov, V; Machhada, A; Marina, N; Mosienko, V; Paton, JF; Teschemacher, AG; Vihko, P, 2015) |
| "Hemorrhagic shock was induced by incremental (0." | 1.42 | Hypertension and vulnerability to hemorrhagic shock in a rat model. ( Reynolds, PS; Song, KS; Tamariz, FJ; Wayne Barbee, R, 2015) |
| "Incident hypertension was defined by self-report or hypertension medication use." | 1.42 | Plasma lactate and incident hypertension in the atherosclerosis risk in communities study. ( Ballantyne, CM; Bower, JK; Hoogeveen, RC; Juraschek, SP; Selvin, E; Subash Shantha, GP; Young, JH, 2015) |
| "Objective of the present investigation was to enhance the bioavailability of felodipine by targeting the M cells of Peyer's patches using PLGA nanoparticles (NPs)." | 1.40 | Improvement in antihypertensive and antianginal effects of felodipine by enhanced absorption from PLGA nanoparticles optimized by factorial design. ( Joshi, G; Sawant, K; Shah, U, 2014) |
| "Development of heart failure is known to be associated with changes in energy substrate metabolism." | 1.39 | Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. ( Basu, R; Clanachan, A; Gandhi, M; Kassiri, Z; Lopaschuk, GD; Mori, J; Oudit, GY; Zhabyeyev, P, 2013) |
| "Is it really septic shock? Our aim was to determine differences in outcome between patients diagnosed as having septic shock but exhibiting normal vs elevated lactate levels during evolution." | 1.37 | Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock? ( Angulo, D; Aranguiz, I; Bruhn, A; Bujes, A; Castro, R; de la Hoz, C; Hernandez, G; Larrondo, J; Romero, C, 2011) |
| "Hypertension-induced pathological cardiac hypertrophy (hypertensive heart) and exercise training-induced physiological cardiac hypertrophy (athletic heart) have differences in cardiac properties." | 1.32 | Cardiac hypertrophy by hypertension and exercise training exhibits different gene expression of enzymes in energy metabolism. ( Fujii, N; Iemitsu, M; Kakinuma, Y; Maeda, S; Matsuda, M; Miyauchi, T; Miyazaki, H; Sakai, S; Yamaguchi, I, 2003) |
| " Dose-response curves for NE-induced perfusion pressure, VO2, and lactate production in SHR were shifted to the left compared with WKY." | 1.30 | Altered muscle metabolism associated with vasoconstriction in spontaneously hypertensive rats. ( Colquhoun, EQ; Ye, JM, 1998) |
| "Glycerol release was lowered by metformin during the 3-h experiment (P<0." | 1.30 | Metformin inhibits catecholamine-stimulated lipolysis in obese, hyperinsulinemic, hypertensive subjects in subcutaneous adipose tissue: an in situ microdialysis study. ( Adler, G; Alt, A; Ditschuneit, HH; Flechtner-Mors, M; Jenkinson, CP, 1999) |
| " Relative bioavailability was significantly increased with Eudragit nanoparticles compared to the nifedipine/PEG solution." | 1.30 | The antihypertensive effect of orally administered nifedipine-loaded nanoparticles in spontaneously hypertensive rats. ( Atkinson, J; Fluckiger, L; Hoffman, M; Kim, YI; Lartaud-Idjouadiene, I; Maincent, P, 1997) |
| "and 1-h cerebral ischemia was then induced by bilateral carotid artery occlusion (group 1)." | 1.28 | Attenuation of ischemic and postischemic damage to brain metabolism and circulation by a novel Ca2+ channel antagonist, NC-1100, in spontaneously hypertensive rats. ( Fujishima, M; Ibayashi, S; Nakane, H; Okada, Y; Ooboshi, H; Sadoshima, S, 1992) |
| "Patients with hypertension have a high incidence of coronary artery disease." | 1.27 | Acute effects of captopril on the coronary circulation of patients with hypertension and angina. ( Burgess, JH; Cousineau, D; Daly, P; Rouleau, JL, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (31.96) | 18.7374 |
| 1990's | 18 (18.56) | 18.2507 |
| 2000's | 20 (20.62) | 29.6817 |
| 2010's | 17 (17.53) | 24.3611 |
| 2020's | 11 (11.34) | 2.80 |
| Authors | Studies |
|---|---|
| Mohammadipour, F | 1 |
| Kiani, A | 1 |
| Amin, A | 1 |
| Su, J | 1 |
| Wang, Y | 1 |
| Yan, M | 1 |
| He, Z | 1 |
| Zhou, Y | 1 |
| Xu, J | 1 |
| Li, B | 1 |
| Xu, W | 1 |
| Yu, J | 1 |
| Chen, S | 1 |
| Lv, G | 1 |
| Li, L | 1 |
| Bai, M | 1 |
| Zhang, Q | 1 |
| Sun, S | 1 |
| Chen, C | 1 |
| Qiao, X | 1 |
| Guo, J | 1 |
| Yang, T | 1 |
| Wang, M | 1 |
| Ma, Y | 1 |
| Zhao, S | 1 |
| Ding, L | 1 |
| Liu, H | 1 |
| Wang, J | 1 |
| Hasan, EK | 1 |
| Mshimesh, BAR | 1 |
| Rzoqi, SS | 1 |
| Aziz, LSA | 1 |
| Khazaal, FAK | 1 |
| Marzooq, AA | 1 |
| Abudlqader, EH | 1 |
| Labastida-García, D | 1 |
| Díaz-Gabriel, G | 1 |
| López-Díaz, F | 1 |
| Gutierrez-Chable, LE | 1 |
| García-Flores, MA | 1 |
| Méndez-Martínez, S | 1 |
| Li, YG | 1 |
| Chang, SL | 1 |
| Xie, JF | 1 |
| Ye, XY | 1 |
| Wang, L | 1 |
| Li, YC | 1 |
| Li, Y | 1 |
| Li, XL | 1 |
| Borghi, F | 1 |
| Morais, CL | 1 |
| Silva, C | 1 |
| da Silva, PC | 1 |
| Ishizu, LY | 1 |
| Costa, GT | 1 |
| Grassi-Kassisse, DM | 1 |
| Zaigham, M | 1 |
| Helfer, S | 1 |
| Kristensen, KH | 1 |
| Isberg, PE | 1 |
| Wiberg, N | 1 |
| Yamagata, K | 1 |
| Wei (魏彤), T | 1 |
| Gao (高晶), J | 1 |
| Huang (黄程淋), C | 1 |
| Song (宋蓓), B | 1 |
| Sun (孙孟炜), M | 1 |
| Shen (沈伟利), W | 1 |
| Wang, Z | 2 |
| Georgieva, KN | 1 |
| Hadjieva, MS | 1 |
| Shishmanova-Doseva, MS | 1 |
| Terzieva, DD | 1 |
| Georgiev, NG | 1 |
| Andreev, GG | 1 |
| Tchekalarova, JD | 1 |
| Young, S | 1 |
| O'Driscoll, R | 1 |
| Antony, M | 1 |
| Whyte, I | 1 |
| Souza, LR | 1 |
| Vicente, JB | 1 |
| Melo, GR | 1 |
| Moraes, VC | 1 |
| Olher, RR | 1 |
| Sousa, IC | 1 |
| Peruchi, LH | 1 |
| Neves, RV | 1 |
| Rosa, TS | 1 |
| Ferreira, AP | 1 |
| Moraes, MR | 2 |
| Chekmeneva, E | 1 |
| Dos Santos Correia, G | 1 |
| Gómez-Romero, M | 1 |
| Stamler, J | 1 |
| Chan, Q | 1 |
| Elliott, P | 1 |
| Nicholson, JK | 1 |
| Holmes, E | 1 |
| Shah, U | 1 |
| Joshi, G | 1 |
| Sawant, K | 1 |
| Smith, C | 1 |
| Viljoen, JT | 1 |
| McGeachie, L | 1 |
| Juraschek, SP | 1 |
| Bower, JK | 1 |
| Selvin, E | 1 |
| Subash Shantha, GP | 1 |
| Hoogeveen, RC | 2 |
| Ballantyne, CM | 2 |
| Young, JH | 2 |
| Reynolds, PS | 1 |
| Song, KS | 1 |
| Tamariz, FJ | 1 |
| Wayne Barbee, R | 1 |
| Marina, N | 1 |
| Ang, R | 1 |
| Machhada, A | 1 |
| Kasymov, V | 1 |
| Karagiannis, A | 1 |
| Hosford, PS | 1 |
| Mosienko, V | 1 |
| Teschemacher, AG | 1 |
| Vihko, P | 1 |
| Paton, JF | 1 |
| Kasparov, S | 1 |
| Gourine, AV | 1 |
| Arora, A | 1 |
| Shafiq, N | 1 |
| Jain, S | 1 |
| Khuller, GK | 1 |
| Sharma, S | 1 |
| Malhotra, S | 1 |
| Akasaka, T | 1 |
| Hokimoto, S | 1 |
| Sueta, D | 1 |
| Tabata, N | 1 |
| Sakamoto, K | 1 |
| Yamamoto, E | 1 |
| Yamamuro, M | 1 |
| Tsujita, K | 1 |
| Kojima, S | 1 |
| Kaikita, K | 1 |
| Kajiwara, A | 1 |
| Morita, K | 1 |
| Oniki, K | 1 |
| Saruwatari, J | 1 |
| Nakagawa, K | 1 |
| Ogata, Y | 1 |
| Ogawa, H | 1 |
| Pinto, RR | 1 |
| Karabulut, M | 1 |
| Poton, R | 1 |
| Polito, MD | 1 |
| Crawford, SO | 1 |
| Ambrose, MS | 1 |
| Brancati, FL | 1 |
| Phillips, SA | 1 |
| Baker, WL | 1 |
| Kluger, J | 1 |
| White, CM | 1 |
| Dale, KM | 1 |
| Silver, BB | 1 |
| Coleman, CI | 1 |
| Hernandez, G | 1 |
| Castro, R | 1 |
| Romero, C | 1 |
| de la Hoz, C | 1 |
| Angulo, D | 1 |
| Aranguiz, I | 1 |
| Larrondo, J | 1 |
| Bujes, A | 1 |
| Bruhn, A | 1 |
| Morais, PK | 1 |
| Campbell, CS | 1 |
| Sales, MM | 1 |
| Motta, DF | 1 |
| Moreira, SR | 1 |
| Cunha, VN | 1 |
| Benford, RE | 1 |
| Simões, HG | 1 |
| Almeida, JA | 1 |
| Petriz, Bde A | 1 |
| da Costa Gomes, CP | 1 |
| Pereira, RW | 1 |
| Franco, OL | 1 |
| Zhabyeyev, P | 1 |
| Gandhi, M | 1 |
| Mori, J | 1 |
| Basu, R | 1 |
| Kassiri, Z | 1 |
| Clanachan, A | 1 |
| Lopaschuk, GD | 1 |
| Oudit, GY | 1 |
| Schachtrupp, A | 1 |
| Toens, Ch | 1 |
| Hoer, J | 1 |
| Klosterhalfen, B | 1 |
| Lawong, AG | 1 |
| Schumpelick, V | 1 |
| KOKHTAREVA, KA | 1 |
| MUIRHEAD, EE | 1 |
| JONES, F | 1 |
| STIRMAN, JA | 1 |
| GUETTLER, F | 1 |
| CLAUSEN, J | 1 |
| PEDERSEN, A | 1 |
| SCHIOLER, M | 1 |
| PHILLIPSON, EA | 1 |
| SPROULE, BJ | 1 |
| PAPPER, S | 1 |
| BELSKY, JL | 1 |
| BLEIFER, KH | 1 |
| Iemitsu, M | 1 |
| Miyauchi, T | 1 |
| Maeda, S | 1 |
| Sakai, S | 1 |
| Fujii, N | 1 |
| Miyazaki, H | 1 |
| Kakinuma, Y | 1 |
| Matsuda, M | 1 |
| Yamaguchi, I | 1 |
| Bourgoin, A | 1 |
| Leone, M | 1 |
| Delmas, A | 1 |
| Garnier, F | 1 |
| Albanèse, J | 1 |
| Martin, C | 1 |
| Chang, CP | 1 |
| Chen, SH | 1 |
| Lin, MT | 1 |
| Fujiwara, M | 1 |
| Arifuku, K | 1 |
| Ando, I | 1 |
| Nemoto, T | 1 |
| Boschmann, M | 1 |
| Kreuzberg, U | 1 |
| Engeli, S | 1 |
| Adams, F | 1 |
| Franke, G | 1 |
| Klaua, S | 1 |
| Scholze, J | 1 |
| Weidinger, G | 1 |
| Luft, FC | 1 |
| Sharma, AM | 1 |
| Jordan, J | 1 |
| Podesser, BK | 1 |
| Jain, M | 1 |
| Ngoy, S | 1 |
| Apstein, CS | 1 |
| Eberli, FR | 1 |
| Hamada, T | 2 |
| Mizuta, E | 1 |
| Yanagihara, K | 1 |
| Kaetsu, Y | 1 |
| Sugihara, S | 1 |
| Sonoyama, K | 1 |
| Yamamoto, Y | 1 |
| Kato, M | 2 |
| Igawa, O | 2 |
| Shigemasa, C | 2 |
| Inokuchi, T | 1 |
| Yamamoto, T | 1 |
| Shimada, T | 2 |
| Ohtahara, A | 1 |
| Ninomiya, H | 1 |
| Hisatome, I | 2 |
| Bacurau, RF | 1 |
| Ramalho, JD | 1 |
| Reis, FC | 1 |
| Casarini, DE | 1 |
| Chagas, JR | 1 |
| Oliveira, V | 1 |
| Higa, EM | 1 |
| Abdalla, DS | 1 |
| Pesquero, JL | 1 |
| Pesquero, JB | 1 |
| Araujo, RC | 1 |
| Wibbens, B | 1 |
| Bennet, L | 1 |
| Westgate, JA | 1 |
| De Haan, HH | 1 |
| Wassink, G | 1 |
| Gunn, AJ | 1 |
| Koch, G | 1 |
| Franz, IW | 1 |
| Gubba, A | 1 |
| Lohmann, FW | 1 |
| Lager, I | 1 |
| Ostman, J | 1 |
| Finnström, O | 1 |
| Ezitis, J | 1 |
| Rydén, G | 1 |
| Wichman, K | 1 |
| Gelmers, HJ | 1 |
| Daly, P | 1 |
| Rouleau, JL | 1 |
| Cousineau, D | 1 |
| Burgess, JH | 1 |
| Paulev, PE | 1 |
| Jordal, R | 1 |
| Kristensen, O | 1 |
| Ladefoged, J | 1 |
| Klein, AA | 1 |
| McCrory, WW | 1 |
| Engle, MA | 1 |
| Rosenthal, R | 1 |
| Ehlers, KH | 1 |
| Frisk Holmberg, M | 1 |
| Juhlin Dannfelt, A | 1 |
| Kaiser, P | 1 |
| Rössner, S | 1 |
| Eliasson, K | 1 |
| Hylander, B | 1 |
| Arner, A | 1 |
| Sethna, DH | 1 |
| Moffitt, EA | 1 |
| Bussell, JA | 1 |
| Raymond, MJ | 1 |
| Matloff, JM | 1 |
| Gray, RJ | 1 |
| Nakatomi, Y | 1 |
| Wikander, I | 1 |
| Roos, T | 1 |
| Stakkestad, A | 1 |
| Eriksson, E | 1 |
| McCoy, DE | 1 |
| Steele, JE | 1 |
| Cox, RH | 1 |
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| Laakso, M | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Capillary Refill Time Response to a Rapid Fluid Challenge in Septic Shock Patients: Pathophysiological Determinants, and Relation to Changes in Systemic, Regional and Microcirculatory Blood Flow[NCT04693923] | 42 participants (Anticipated) | Interventional | 2021-02-01 | Not yet recruiting | |||
| Early Goal Directed Therapy Using a Physiological Holistic View. A Multicenter Study in Latin America: The ANDROMEDA-SHOCK Study[NCT03078712] | 424 participants (Actual) | Interventional | 2017-03-01 | Completed | |||
| Effect of Vasopressin on Kidney and Cardiac Function in Previously Hypertensive Patients With Septic Shock: A Randomized Clinical Trial[NCT06125184] | 50 participants (Anticipated) | Interventional | 2022-11-01 | Recruiting | |||
| New Electrophoretic Approaches in Studies of Obesity and Diabetes[NCT03189732] | 10 participants (Actual) | Interventional | 2015-10-01 | Completed | |||
| An Observational Study to Identify BEnefits After 24 Weeks of NEBILET®(Nebivolol) Administration For Essential hypertensIon Patients With Various Co-morbidities and Treatment Environments in KOREA.[NCT03847350] | 3,250 participants (Actual) | Observational | 2015-07-01 | Completed | |||
| Effects of Nebivolol on Microvascular Perfusion in the Skeletal Muscles During Exercise in Hypertensive Patients[NCT01501929] | Phase 4 | 32 participants (Actual) | Interventional | 2010-08-31 | Completed | ||
| Walking Intervention in African American Adults With Newly Diagnosed Hypertension[NCT00298207] | 20 participants | Interventional | 2001-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Endothelial cell (EC) was collected after a 20-guage angiocatheter was inserted into the contralateral forearm vein under sterile conditions. Three J-shaped vascular guidewires (St. Jude, St. Paul, MN) were advanced sequentially into the vein up to 10 cm. Endothelial cells were collected by gentle abrasion and placed into a dissociation buffer (0.5% bovine serum albumin, 2mM EDTA, and 100 ug/ml heparin in PBS). Endothelial cells were recovered from the tips of guide wires by repeated washing into collection tubes and subsequent centrifugation. EC were incubated with monoclonal antibodies against the polyclonal antibodies against NADPH oxidase p47 subunit. The intensity of staining was measured using fluorescence microscopy. (NCT01501929)
Timeframe: 12 weeks
| Intervention | Ratio human to HUVEC p47Phox expression (Mean) |
|---|---|
| Metoprolol | 0.47 |
| Nebivolol | 0.44 |
Microvascular perfusion of skeletal muscle were measured during handgrip at 20 cycle per minute after 12 weeks of metoprolol, and after 12 weeks of nebivolol (NCT01501929)
Timeframe: 12 weeks
| Intervention | video intensity units/ second (Median) |
|---|---|
| Metoprolol | 43.938 |
| Nebivolol | 74.584 |
7 reviews available for lactic acid and Hypertension
| Article | Year |
|---|---|
The High Potency of Polymeric Nanoparticles in the Drug Delivery System for Hypertension Treatment: A Systematic Review.
Topics: Antihypertensive Agents; Drug Delivery Systems; Humans; Hypertension; Lactic Acid; Nanoparticles; Po | 2022 |
Astrocytic nutritional dysfunction associated with hypoxia-induced neuronal vulnerability in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Astrocytes; Cell Death; Cells, Cultured; Humans; Hypertension; Hypoxia; Lactic Acid; Neuron | 2020 |
beta-adrenergic blockade and diabetes mellitus. A review.
Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; D | 1983 |
The neurology of hypertension, a neurologist view.
Topics: Adult; Blood-Brain Barrier; Carbon Dioxide; Cerebrovascular Circulation; Cerebrovascular Disorders; | 1982 |
Energy turnover and mechanical properties of smooth muscle. With observations on vascular smooth muscle structure and function in the hypertensive rat.
Topics: Adenosine Triphosphate; Animals; Aorta; Calcium; Energy Metabolism; Female; Guinea Pigs; Hypertensio | 1982 |
Biochemical indices associated with meditation practice: a literature review.
Topics: Aldosterone; Blood Circulation; Catecholamines; Cholesterol; Dopamine beta-Hydroxylase; Growth Hormo | 1985 |
Muscle exercise, energy metabolism and blood lactate.
Topics: Adrenergic beta-Antagonists; Adult; Energy Metabolism; Exercise Test; Humans; Hypertension; Lactates | 1986 |
14 trials available for lactic acid and Hypertension
| Article | Year |
|---|---|
EFFECT OF MAGNESIUM L-LACTATE SUPPLEMENT ON BLOOD PRESSURE AND CORRECTED QT INTERVAL IN A SAMPLE OF IRAQI WOMEN WITH METABOLIC SYNDROME.
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hypertension; Iraq; Lactic Ac | 2023 |
Acute resistance exercise with blood flow restriction in elderly hypertensive women: haemodynamic, rating of perceived exertion and blood lactate.
Topics: Age Factors; Aged; Aging; Biomarkers; Cross-Over Studies; Female; Hemodynamics; Humans; Hypertension | 2018 |
Effect of magnesium L-lactate on blood pressure in patients with an implantable cardioverter defibrillator.
Topics: Aged; Blood Pressure; Defibrillators, Implantable; Double-Blind Method; Female; Follow-Up Studies; H | 2009 |
Increasing mean arterial pressure in patients with septic shock: effects on oxygen variables and renal function.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Creatinine; Female; Humans; Hypertension; Hypotensio | 2005 |
The effect of oral glucose loads on tissue metabolism during angiotensin II receptor and beta-receptor blockade in obese hypertensive subjects.
Topics: Adipose Tissue; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Blo | 2006 |
Increase in kinins on post-exercise hypotension in normotensive and hypertensive volunteers.
Topics: Adult; Blood Pressure; Exercise; Health; Humans; Hypertension; Kallikreins; Kinins; Lactic Acid; Mal | 2007 |
beta-adrenoceptor blockade and physical activity: cardiovascular and metabolic aspects.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Blood Glucose; Catecholamines; Hemodynamics; Humans; | 1983 |
Neonatal effects of beta-blocking drugs in pregnancy.
Topics: Adrenergic beta-Antagonists; Apgar Score; Birth Weight; Carbon Dioxide; Cephalometry; Clinical Trial | 1984 |
Therapeutic and metabolic effects of sotalol.
Topics: Adult; Blood Pressure; Catecholamines; Heart Rate; Humans; Hypertension; Lactates; Lactic Acid; Lipi | 1984 |
Crossover comparison between the depressor effects of low and high work-rate exercise in mild hypertension.
Topics: Adult; Analysis of Variance; Blood Pressure; Exercise; Female; Hemodynamics; Humans; Hypertension; J | 1993 |
Effects of losartan on insulin sensitivity in hypertensive subjects.
Topics: Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Fatty Acids, Nones | 1996 |
Catecholamines response of high performance wheelchair athletes at rest and during exercise with autonomic dysreflexia.
Topics: Adult; Autonomic Dysreflexia; Catecholamines; Disabled Persons; Exercise; Heart Rate; Humans; Hypert | 2001 |
Integrated effects of the vasodilating beta-blocker nebivolol on exercise performance, energy metabolism, cardiovascular and neurohormonal parameters in physically active patients with arterial hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Analysis of Variance; Benzopyrans; beta-Endorphin; Blood Glucose | 2001 |
Antihypertensive and volume-depleting effects of mild exercise on essential hypertension.
Topics: Adult; Blood Volume; Body Weight; Electrolytes; Exercise Therapy; Female; Hemodynamics; Humans; Hype | 1987 |
76 other studies available for lactic acid and Hypertension
| Article | Year |
|---|---|
The beneficial effects of Polygonatum sibiricum Red. superfine powder on metabolic hypertensive rats via gut-derived LPS/TLR4 pathway inhibition.
Topics: Animals; Claudin-1; Endothelin-1; Eosine Yellowish-(YS); Fatty Acids, Volatile; Hematoxylin; Hyperte | 2022 |
Characteristics and predictors of ICU-mortality in critically ill patients with hyperlactatemia requiring CRRT: A retrospective cohort study.
Topics: Acute Kidney Injury; Adult; Aged; Continuous Renal Replacement Therapy; Critical Illness; Humans; Hy | 2022 |
Related factors based on non-targeted metabolomics methods in minor ischaemic stroke.
Topics: Biomarkers; Blood Glucose; Brain Ischemia; C-Reactive Protein; Homocysteine; Humans; Hypertension; I | 2022 |
Lactate and pH values in newborns with a history of acute fetal distress.
Topics: Cross-Sectional Studies; Female; Fetal Distress; Humans; Hydrogen-Ion Concentration; Hypertension; I | 2023 |
[Analysis of clinical characteristics and risk factors of death in critical burn patients complicated with invasive fungal infection].
Topics: Burns; Female; Glucans; Humans; Hypertension; Interleukin-6; Invasive Fungal Infections; Lactic Acid | 2023 |
A new perspective of lactatogenesis by isolated adipocytes.
Topics: Adipocytes; Animals; Body Weight; Fasting; Glucose; Hyperlactatemia; Hypertension; Lactic Acid; Male | 2019 |
Maternal arterial blood gas values during delivery: Effect of mode of delivery, maternal characteristics, obstetric interventions and correlation to fetal umbilical cord blood.
Topics: Adult; Anesthesia, Epidural; Blood Gas Analysis; Cesarean Section; Correlation of Data; Delivery, Ob | 2020 |
SIRT3 (Sirtuin-3) Prevents Ang II (Angiotensin II)-Induced Macrophage Metabolic Switch Improving Perivascular Adipose Tissue Function.
Topics: Acetylation; Adipose Tissue, Brown; Angiotensin II; Animals; Cell Plasticity; Disease Models, Animal | 2021 |
Identification of risk factors for in-hospital death of COVID - 19 pneumonia -- lessions from the early outbreak.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antivira | 2021 |
Effect of Training at Lactate Threshold Intensity on Maximal Time to Exhaustion, Depression and Anxiety Behaviour of Spontaneously Hypertensive Rats after Kainate-Induced Status Epilepticus.
Topics: Animals; Anxiety; Behavior, Animal; Comorbidity; Depression; Disease Models, Animal; Essential Hyper | 2017 |
Massive eucalyptus oil overdose.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidotes; Charcoal; Citalopram; Coma; Drug Overdos | 2017 |
Acute Hypotension After Moderate-Intensity Handgrip Exercise in Hypertensive Elderly People.
Topics: Aged; Blood Pressure; Blood Pressure Determination; Cardiovascular System; Exercise; Female; Hand St | 2018 |
Ultra-Performance Liquid Chromatography-High-Resolution Mass Spectrometry and Direct Infusion-High-Resolution Mass Spectrometry for Combined Exploratory and Targeted Metabolic Profiling of Human Urine.
Topics: Adult; Alanine; Chromatography, High Pressure Liquid; Creatine; Creatinine; Female; Humans; Hyperten | 2018 |
Improvement in antihypertensive and antianginal effects of felodipine by enhanced absorption from PLGA nanoparticles optimized by factorial design.
Topics: Absorption; Administration, Oral; Angina, Unstable; Animals; Antihypertensive Agents; Cardiotonic Ag | 2014 |
African drumming: a holistic approach to reducing stress and improving health?
Topics: Adult; Aging; Anxiety; Blood Pressure; Exercise; Female; Heart Rate; Holistic Health; Humans; Hypert | 2014 |
Plasma lactate and incident hypertension in the atherosclerosis risk in communities study.
Topics: Aged; Cohort Studies; Female; Humans; Hypertension; Incidence; Lactic Acid; Longitudinal Studies; Ma | 2015 |
Hypertension and vulnerability to hemorrhagic shock in a rat model.
Topics: Animals; Blood Pressure; Hemodynamics; Hypertension; Lactic Acid; Male; Muscle, Skeletal; Oxygen Con | 2015 |
Brainstem hypoxia contributes to the development of hypertension in the spontaneously hypertensive rat.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Brain Stem; Disease Models, Animal; Disease Progres | 2015 |
Development of Sustained Release "NanoFDC (Fixed Dose Combination)" for Hypertension - An Experimental Study.
Topics: Amlodipine; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium Channel Bl | 2015 |
Sex differences in the impact of CYP2C19 polymorphisms and low-grade inflammation on coronary microvascular disorder.
Topics: Aged; Biomarkers; C-Reactive Protein; Case-Control Studies; Chi-Square Distribution; Coronary Artery | 2016 |
Association of lactate with blood pressure before and after rapid weight loss.
Topics: Adipose Tissue; Adult; Aged; Biomarkers; Blood Pressure; Body Mass Index; Case-Control Studies; Diet | 2008 |
Obesity, weight loss, and cardiovascular health: is oxidative capacity a missing link?
Topics: Biomarkers; Cardiovascular Diseases; Coronary Disease; Evidence-Based Medicine; Humans; Hypertension | 2008 |
Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock?
Topics: Acidosis, Lactic; Algorithms; APACHE; Biomarkers; Chi-Square Distribution; Female; Humans; Hypertens | 2011 |
Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock?
Topics: Acidosis, Lactic; Algorithms; APACHE; Biomarkers; Chi-Square Distribution; Female; Humans; Hypertens | 2011 |
Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock?
Topics: Acidosis, Lactic; Algorithms; APACHE; Biomarkers; Chi-Square Distribution; Female; Humans; Hypertens | 2011 |
Persistent sepsis-induced hypotension without hyperlactatemia: is it really septic shock?
Topics: Acidosis, Lactic; Algorithms; APACHE; Biomarkers; Chi-Square Distribution; Female; Humans; Hypertens | 2011 |
Acute resistance exercise is more effective than aerobic exercise for 24h blood pressure control in type 2 diabetics.
Topics: Bicycling; Blood Pressure; Diabetes Mellitus, Type 2; Exercise; Female; Heart Rate; Humans; Hyperten | 2011 |
Assessment of maximal lactate steady state during treadmill exercise in SHR.
Topics: Animals; Biomarkers; Disease Models, Animal; Exercise Therapy; Female; Hypertension; Lactic Acid; Mu | 2012 |
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload.
Topics: Acetyl Coenzyme A; Animals; Echocardiography; Glucose; Glucose Transporter Type 4; Heart Failure; Hy | 2013 |
A 24-h pneumoperitoneum leads to multiple organ impairment in a porcine model.
Topics: Alkaline Phosphatase; Animals; Blood Pressure; Cardiac Output; Central Venous Pressure; Compartment | 2002 |
[Relationship between vitamin B1, cocarboxylase, pyroacetic acid, lactic acid, and inorganic phosphorus in hypertension].
Topics: Acids; Humans; Hypertension; Lactic Acid; Phosphorus; Thiamine; Thiamine Pyrophosphate | 1952 |
Potentiation of renoprival hypertension by alanine, pyruvate and lactate.
Topics: Alanine; Humans; Hypertension; Hypertension, Renal; Lactates; Lactic Acid; Nephrectomy; Pyruvates; P | 1957 |
[THE LACTIC ACID DEHYDROGENASE ISOZYME PATTERN OF THE UNILATERAL KIDNEY PELVIS URINE FROM PATIENTS WITH HYPERTENSION].
Topics: Angiography; Electrophoresis; Hypertension; Hypertension, Renal; Isoenzymes; Kidney; Kidney Pelvis; | 1963 |
THE CLINICAL SIGNIFICANCE OF ELEVATED BLOOD LACTATE.
Topics: Acidosis; Acidosis, Lactic; Blood; Chemical Phenomena; Chemistry; Geriatrics; Humans; Hypertension; | 1965 |
The response to the administration of an isotonic sodium chloride-lactate solution in patients with essential hypertension.
Topics: Essential Hypertension; Humans; Hypertension; Lactates; Lactic Acid; Sodium Chloride | 1960 |
Cardiac hypertrophy by hypertension and exercise training exhibits different gene expression of enzymes in energy metabolism.
Topics: Animals; Cardiomegaly; Carnitine O-Palmitoyltransferase; CD36 Antigens; Coenzyme A Ligases; Fatty Ac | 2003 |
Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke.
Topics: Anesthesia; Animals; Brain; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Glutamic Acid; | 2005 |
Pattern recognition analysis for classification of hypertensive model rats and diurnal variation using 1H-NMR spectroscopy of urine.
Topics: Animals; Circadian Rhythm; Citric Acid; Hypertension; Lactic Acid; Magnetic Resonance Spectroscopy; | 2005 |
Unveiling gender differences in demand ischemia: a study in a rat model of genetic hypertension.
Topics: Animals; Coronary Circulation; Diastole; Disease Models, Animal; Disease Susceptibility; Female; Hyp | 2007 |
Plasma levels of uridine correlate with blood pressure and indicators of myogenic purine degradation and insulin resistance in hypertensive patients.
Topics: Ammonia; Blood Pressure; Case-Control Studies; Exercise; Female; Humans; Hypertension; Hypoxanthine; | 2007 |
Preexisting hypoxia is associated with a delayed but more sustained rise in T/QRS ratio during prolonged umbilical cord occlusion in near-term fetal sheep.
Topics: Amniotic Fluid; Animals; Blood Gas Analysis; Blood Glucose; Blood Pressure; Carotid Arteries; Data I | 2007 |
Adrenergic blockade and hypoglycaemia.
Topics: Adrenergic beta-Antagonists; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Glucag | 1983 |
Acute effects of captopril on the coronary circulation of patients with hypertension and angina.
Topics: Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Coronary | 1984 |
Therapeutic effect of exercise on hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Catecholamines; Female; Heart Rate; Humans; Hypertension; Lactat | 1984 |
Sympathetic nervous system and exercise tolerance response in normotensive and hypertensive adolescents.
Topics: Adolescent; Blood Pressure; Cardiac Output; Echocardiography; Electrocardiography; Epinephrine; Fema | 1984 |
Intravenous nitroglycerin and myocardial metabolism during anesthesia in patients undergoing myocardial revascularization.
Topics: Anesthesia; Coronary Artery Bypass; Coronary Circulation; Humans; Hypertension; Infusions, Parentera | 1982 |
[Effect of recirculation on experimental cerebral ischemia. 3. Therapy].
Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Carotid Arteries; Cerebrovascular Circulatio | 1982 |
Sodium lactate elicits a rapid increase in blood pressure in Wistar rats and spontaneously hypertensive rats. Effect of pretreatment with the antipanic drugs clomipramine and alprazolam.
Topics: Alprazolam; Animals; Blood Pressure; Clomipramine; Heart Rate; Hypertension; Injections, Intravenous | 1995 |
Swim training alters sympathoadrenal and endocrine responses to hemorrhage in borderline hypertensive rats.
Topics: Adrenal Glands; Animals; Blood Glucose; Blood Pressure; Catecholamines; Endocrine Glands; Heart Rate | 1995 |
Ischemic dysfunction and impaired recovery in hypertensive hypertrophied hearts is associated with exaggerated intracellular sodium accumulation.
Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Hydrogen-Ion Concentration; Hypertension; Lactates; L | 1994 |
Effects of heart rate on coronary circulation and external mechanical efficiency in elderly hypertensive patients with left ventricular hypertrophy.
Topics: Aged; Analysis of Variance; Coronary Circulation; Heart Failure; Heart Rate; Hemodynamics; Humans; H | 1996 |
The antihypertensive effect of orally administered nifedipine-loaded nanoparticles in spontaneously hypertensive rats.
Topics: Acrylic Resins; Animals; Antihypertensive Agents; Area Under Curve; Blood Pressure; Calcium Channel | 1997 |
Possible synergistic effect of metformin and enalapril on the development of hyperkaliemic lactic acidosis.
Topics: Acidosis; Aged; Antihypertensive Agents; Chlorides; Diabetes Mellitus, Type 2; Drug Synergism; Drug | 1997 |
Response of insulin, glucagon, lactate, and nonesterified fatty acids to glucose in visceral obesity with and without NIDDM: relationship to hypertension.
Topics: Adult; Blood Pressure; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucagon; Gluc | 1998 |
Exercise training in female patients with a family history of hypertension.
Topics: Blood Pressure; Exercise; Female; Heart Rate; Hematocrit; Humans; Hypertension; Lactic Acid; Lipids; | 1998 |
Altered muscle metabolism associated with vasoconstriction in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Glucose; Hypertension; Lactic Acid | 1998 |
Metformin inhibits catecholamine-stimulated lipolysis in obese, hyperinsulinemic, hypertensive subjects in subcutaneous adipose tissue: an in situ microdialysis study.
Topics: Adipose Tissue; Adult; Body Mass Index; Electric Impedance; Epinephrine; Female; Glycerol; Humans; H | 1999 |
Effects of maternal captopril treatment on growth, blood glucose and plasma insulin in the fetal spontaneously hypertensive rat.
Topics: Animals; Blood Glucose; Captopril; Drinking; Female; Fetal Blood; Fetal Diseases; Fetal Weight; Gest | 1999 |
Altered purine nucleotide degradation during exercise in patients with essential hypertension.
Topics: Exercise Test; Female; Humans; Hypertension; Hypoxanthine; Lactic Acid; Male; Middle Aged; Purine Nu | 2001 |
Effects of prolonged increased intra-abdominal pressure on gastrointestinal blood flow in pigs.
Topics: Animals; Digestive System; Hemodynamics; Hypertension; Injections, Intravenous; Intestine, Small; Is | 2001 |
[Effect of the imidazoline receptor agonist moxonidine on hemodynamics, coronary circulation, metabolic ischemia markers and the neurohumoral system in patients with essential hypertension. Effects of moxonidine on coronary circulation].
Topics: Aged; Angina Pectoris; Antihypertensive Agents; Blood Flow Velocity; Coronary Circulation; Electroca | 2001 |
Metabolic changes in DOCA-salt hypertensive rats.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Animals; Blood Glucose; Cholesterol; Citrate (si)-Synthase; Desoxy | 2000 |
Endogenous nitric oxide prevents myocardial ischemia in patients with hypertension and left ventricular hypertrophy.
Topics: Aged; Cardiac Catheterization; Coronary Circulation; Enzyme Inhibitors; Female; Humans; Hypertension | 2002 |
Attenuation of ischemic and postischemic damage to brain metabolism and circulation by a novel Ca2+ channel antagonist, NC-1100, in spontaneously hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Brain; Brain Ischemia; Calcium Channel Blockers; Ce | 1992 |
[Intestinal calcium absorption in hypertension patients].
Topics: Adult; Calcitonin; Calcitriol; Calcium; Chronic Disease; Creatinine; Humans; Hypertension; Intestina | 1992 |
Impaired cardiopulmonary response to exercise in moderate hypertension.
Topics: Adult; Cardiomegaly; Exercise; Exercise Test; Female; Hemodynamics; Humans; Hypertension; Lactates; | 1992 |
Evidence for increased in vivo Na(+)-H+ antiporter activity and an altered skeletal muscle contractile response in the spontaneously hypertensive rat.
Topics: Amiloride; Animals; Carrier Proteins; Cytosol; Glycogen; Hypertension; Isometric Contraction; Lactat | 1990 |
[Changes in the glycolytic pathway in patients with essential arterial hypertension].
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Aged; Diphosphoglyceric Acids; Glycolysis; Hu | 1990 |
Metabolic characteristics of aorta from spontaneously hypertensive and renal and deoxycorticosterone acetate-salt hypertensive rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Desoxycorticosterone; Hypertension; Hypertension, Renal; I | 1986 |
Regulation of ventricular atrial natriuretic peptide release in hypertrophied rat myocardium. Effects of exercise.
Topics: Animals; Atrial Natriuretic Factor; Cardiomegaly; Catecholamines; Heart Ventricles; Hypertension; La | 1989 |
Effect of prazosin treatment on carbohydrate and lipoprotein metabolism in patients with hypertension.
Topics: Adult; Blood Glucose; Dietary Carbohydrates; Fatty Acids, Nonesterified; Female; Humans; Hypertensio | 1989 |
Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites.
Topics: Adenosine; Animals; Brain; Brain Ischemia; Cerebral Hemorrhage; Cerebrovascular Circulation; Extrace | 1989 |
Control of intraoperative hypertension with isoflurane in patients with coronary artery disease: effects on regional myocardial blood flow and metabolism.
Topics: Adult; Aged; Anesthesia, General; Coronary Artery Bypass; Coronary Circulation; Coronary Disease; Hu | 1989 |
Blood pressure response in relation to blood lactate during exercise in patients with essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Exercise Test; Heart Rate; Humans; Hypertension; | 1985 |
[Effect of long-term prior antihypertensive treatment on cerebral ischemia induced by bilateral common carotid artery ligation in SHRSR].
Topics: Adenosine Triphosphate; Animals; Body Water; Brain; Brain Ischemia; Captopril; Carotid Arteries; Cer | 1986 |
Susceptibility to ischemic insult in hypertensive rats: correlation between degree of ischemia and hypertension.
Topics: Adenosine Triphosphate; Animals; Body Water; Brain; Brain Ischemia; Carotid Arteries; Cerebrovascula | 1986 |
Effect of calcium supplementation on blood pressure in essential hypertensive subjects.
Topics: Adult; Aged; Blood Pressure; Calcium; Female; Heart Rate; Humans; Hypertension; Lactates; Lactic Aci | 1987 |
Calcium appetite, blood pressure and electrolytes in spontaneously hypertensive rats.
Topics: Animals; Appetite; Blood Pressure; Calcium; Calcium Chloride; Calcium, Dietary; Electrolytes; Hypert | 1986 |
Essential hypertension: a metabolic cause? A hypothesis.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Calcium; Captopril; Female; Humans; Hydrochlorothiazide; H | 1985 |