Page last updated: 2024-12-11

pseudolaric acid b

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth
FloraRankFlora DefinitionFamilyFamily Definition
Pseudolarixgenus[no description available]PinaceaeA plant family of the order Pinales, class Pinopsida, division Tracheophyta, known for the various conifers.[MeSH]
Pseudolarix kaempferispecies[no description available]PinaceaeA plant family of the order Pinales, class Pinopsida, division Tracheophyta, known for the various conifers.[MeSH]

Cross-References

ID SourceID
PubMed CID146159853
MeSH IDM0162844

Synonyms (1)

Synonym
pseudolaric acid b ,

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" This method was successfully applied to the pharmacokinetic studies of PAB in Sprague-Dawley rats."( Development and validation of LC-MS/MS method for quantification of pseudolaric acid B from the root bark of Pseudolarix kaempferi in rat plasma: application to a pharmacokinetic study.
Feng, X; Suo, J; Wang, H; Wang, Y; Zhang, N, 2015
)
0.42

Compound-Compound Interactions

ExcerptReferenceRelevance
"Angiogenesis inhibitors combined with chemotherapeutic drugs have significant efficacy in the treatment of a variety of cancers."( Angiogenesis inhibition and cell cycle arrest induced by treatment with Pseudolarix acid B alone or combined with 5-fluorouracil.
Chu, M; Cui, J; Fu, H; Guo, W; Liu, J; Ran, F; Xu, B, 2012
)
0.38

Bioavailability

ExcerptReferenceRelevance
" The aim of this project was to improve the solubility and eventually the dermal permeability and bioavailability by developing a microemulsion based gel for PAB (PAB ME-gel)."( Microemulsion based gel for topical dermal delivery of pseudolaric acid B: In vitro and in vivo evaluation.
Pan, J; Pan, W; Qin, M; Wan, T; Wu, C; Wu, Z; Xu, T; Xu, Y; Zhang, G, 2015
)
0.42

Dosage Studied

ExcerptRelevanceReference
" The pharmacokinetics (C(2min), AUC) of PAB within the used dosage range were in accordance with linear pharmacokinetic characteristics."( Development and validation of LC-MS/MS method for quantification of pseudolaric acid B from the root bark of Pseudolarix kaempferi in rat plasma: application to a pharmacokinetic study.
Feng, X; Suo, J; Wang, H; Wang, Y; Zhang, N, 2015
)
0.42
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (93)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (1.08)18.7374
1990's5 (5.38)18.2507
2000's26 (27.96)29.6817
2010's53 (56.99)24.3611
2020's8 (8.60)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (2.11%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other93 (97.89%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]