meclofenamic acid has been researched along with Hypertension in 21 studies
Meclofenamic Acid: A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
meclofenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " sar1gly8AII, abolished the hypertensive response to acute ureteral obstruction, and pretreatment with 2 mg/kg of either indomethacin (n=6) or meclofenamate (n=3), 15 min before obstruction, prevented the hyperemic response." | 3.66 | Prostaglandin-mediated hyperemia and renin-mediated hypertension during acute ureteral obstruction. ( Aisenbrey, G; Burke, TJ; Cadnapaphornchai, P; McDonald, KM; Schrier, RW, 1978) |
| "The hypertension is accompanied by increases in plasma renin activity and can be prevented with intravenous L-arginine administration." | 1.29 | Long-term cardiovascular role of nitric oxide in conscious rats. ( Brands, MW; Hu, L; Manning, RD, 1994) |
| "Our recent observation that the chronic administration of indomethacin (3." | 1.28 | Resistance of the renal biosynthesis of prostaglandin E2 to the inhibitory effect of indomethacin in the rat in vivo. ( Falardeau, P; Hui, R, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (57.14) | 18.7374 |
| 1990's | 8 (38.10) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pearson, JT | 1 |
| Shirai, M | 1 |
| Yokoyama, C | 1 |
| Tsuchimochi, H | 1 |
| Schwenke, DO | 1 |
| Shimouchi, A | 1 |
| Kangawa, K | 1 |
| Tanabe, T | 1 |
| Ciccone, CD | 1 |
| Zambraski, EJ | 1 |
| Imaizumi, T | 1 |
| Takeshita, A | 1 |
| Ashihara, T | 1 |
| Nakamura, M | 1 |
| Sirén, AL | 1 |
| Weber, PC | 1 |
| Scherer, B | 1 |
| Siess, W | 1 |
| Held, E | 1 |
| Schnermann, J | 1 |
| Chrysant, SG | 2 |
| Mandal, AK | 1 |
| Nordquist, JA | 1 |
| Takase, H | 1 |
| Dohi, Y | 1 |
| Kojima, M | 1 |
| Sato, K | 1 |
| Schricker, K | 1 |
| Hamann, M | 1 |
| Kaissling, B | 1 |
| Kurtz, A | 1 |
| Martínez, FJ | 1 |
| Villa, E | 1 |
| García-Robles, R | 1 |
| Romero, JC | 2 |
| Hu, L | 1 |
| Manning, RD | 1 |
| Brands, MW | 1 |
| Munoz-Garcia, R | 1 |
| Maeso, R | 1 |
| Rodrigo, E | 1 |
| Navarro, J | 1 |
| Ruilope, LM | 1 |
| Casal, MC | 1 |
| Cachofeiro, V | 1 |
| Lahera, V | 1 |
| Krier, JD | 1 |
| Cadnapaphornchai, P | 1 |
| Aisenbrey, G | 1 |
| McDonald, KM | 1 |
| Burke, TJ | 1 |
| Schrier, RW | 1 |
| Tobian, L | 1 |
| O'Donnell, M | 1 |
| Ganguli, M | 1 |
| Levy, JV | 1 |
| Luthin, DR | 1 |
| Cline, WH | 1 |
| Hui, R | 1 |
| Falardeau, P | 2 |
| Martineau, A | 1 |
| Woods, LL | 1 |
| Roman, RJ | 1 |
| Kaldunski, ML | 1 |
| Mattson, DL | 1 |
| Mistry, M | 1 |
| Nasjletti, A | 1 |
1 review available for meclofenamic acid and Hypertension
| Article | Year |
|---|---|
Prostaglandin I2 and glucocorticoid-induced rise in arterial pressure in the rat.
Topics: Animals; Arachidonic Acids; Blood Pressure; Dexamethasone; Epoprostenol; Hypertension; Male; Meclofe | 1989 |
20 other studies available for meclofenamic acid and Hypertension
| Article | Year |
|---|---|
Alpha2-adrenoreceptor mediated sympathoinhibition of heart rate during acute hypoxia is diminished in conscious prostacyclin synthase deficient mice.
Topics: Acute Disease; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cyclooxygenase Inhibitors; Cyt | 2007 |
Effects of phenoxybenzamine, metoprolol, captopril, and meclofenamate on cardiovascular function in deoxycorticosterone acetate hypertensive Yucatan miniature swine.
Topics: Animals; Blood Pressure; Captopril; Desoxycorticosterone; Female; Heart Rate; Hemodynamics; Hyperten | 1983 |
Salt loading augments vascular responses to indomethacin in stroke-prone SHR.
Topics: Alprostadil; Animals; Blood Pressure; Bradykinin; Drinking; Hypertension; Indomethacin; Meclofenamic | 1982 |
Differences in the central actions of arachidonic acid and prostaglandin F2 alpha between spontaneously hypertensive and normotensive rats.
Topics: Animals; Arachidonic Acids; Blood Pressure; Body Temperature; Dinoprost; Dose-Response Relationship, | 1982 |
Possible significance of renal prostaglandins for renin release and blood pressure control.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Blood Pressure; Carbazoles; Feedback; H | 1980 |
Renal functional and organic changes induced by salt and prostaglandin inhibition in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Glomerular Filtration Rate; Hemodynamics; Hypertension; Kidney; Male; Meclo | 1980 |
Changes in the endothelial cyclooxygenase pathway in resistance arteries of spontaneously hypertensive rats.
Topics: Acetylcholine; Adenosine; Animals; Endothelium, Vascular; Hypertension; In Vitro Techniques; Male; M | 1994 |
Renal autacoids are involved in the stimulation of renin gene expression by low perfusion pressure.
Topics: Animals; Arginine; Blood Pressure; Drug Combinations; Gene Expression; Hypertension; Kidney; Male; M | 1994 |
Effect of nitric oxide and prostaglandins on renal function in insulin-resistant hypertensive dogs.
Topics: Acetylcholine; Animals; Arginine; Disease Models, Animal; Diuresis; Dogs; Fructose; Glomerular Filtr | 1993 |
Long-term cardiovascular role of nitric oxide in conscious rats.
Topics: Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Kidne | 1994 |
Acute renal excretory actions of losartan in spontaneously hypertensive rats: role of AT2 receptors, prostaglandins, kinins and nitric oxide.
Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Bip | 1995 |
Systemic inhibition of nitric oxide and prostaglandins in volume-induced natriuresis and hypertension.
Topics: Animals; Blood Pressure; Body Weight; Cyclooxygenase Inhibitors; Diuresis; Dogs; Drug Interactions; | 1998 |
Effects of high salt intake and meclofenamate on arterial pressure and renal function in the spontaneously hypertensive rat.
Topics: Animals; Arteries; Blood Pressure; Glomerular Filtration Rate; Hypertension; Kidney; Male; Meclofena | 1979 |
Prostaglandin-mediated hyperemia and renin-mediated hypertension during acute ureteral obstruction.
Topics: Acute Disease; Angiotensin II; Animals; Dogs; Female; Hyperemia; Hypertension; Indomethacin; Kidney; | 1978 |
Relationship of prostaglandins and sodium in renal papilla in Kyoto hypertensive rats and during high sodium diets.
Topics: Age Factors; Animals; Diet; Hypertension; Indomethacin; Kidney Medulla; Meclofenamic Acid; Prostagla | 1978 |
Changes in systolic arterial blood pressure in normal and spontaneously hypertensive rats produced by acute administration of inhibitors of prostaglandin biosynthesis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Benzothiazoles; Blood Pressure; Fenoprofen; Hypertension; | 1977 |
Evidence for enhanced inhibitory modulation by cyclooxygenase products of noradrenergic neurotransmission in the mesenteric vasculature of young spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cocaine; Cyclooxygenase Inhibitors; Heart Rate; Hypertension; Indomethacin; | 1991 |
Resistance of the renal biosynthesis of prostaglandin E2 to the inhibitory effect of indomethacin in the rat in vivo.
Topics: Alprostadil; Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Resistance; Epoproste | 1990 |
Importance of prostaglandins in hypertension during reduced uteroplacental perfusion pressure.
Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Fatty Acids, Unsaturated; Fe | 1989 |
Influence of eicosanoids on renal function of DOCA-salt hypertensive rats.
Topics: Animals; Benzofurans; Body Water; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Fat | 1988 |