Proteins > C-C chemokine receptor type 1
Page last updated: 2024-08-07 21:10:50
C-C chemokine receptor type 1
A C-C chemokine receptor type 1 that is encoded in the genome of mouse. [OMA:P51675, PRO:DNx]
Synonyms
C-C CKR-1;
CC-CKR-1;
CCR-1;
CCR1;
Macrophage inflammatory protein 1-alpha receptor;
MIP-1alpha-R;
RANTES-R
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (4)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| bx 471 | Mus musculus (house mouse) | IC50 | 0.6150 | 1 | 1 |
| ucb 35625 | Mus musculus (house mouse) | IC50 | 0.1569 | 3 | 5 |
| vuf 2274 | Mus musculus (house mouse) | IC50 | 5.0000 | 1 | 1 |
| incb3344 | Mus musculus (house mouse) | IC50 | 1.0000 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| bx 471 | Mus musculus (house mouse) | Kd | 0.2000 | 1 | 1 |
Chemokine receptor antagonists.Journal of medicinal chemistry, , Nov-26, Volume: 55, Issue:22, 2012
Structure-activity relationships of novel, highly potent, selective, and orally active CCR1 antagonists.Bioorganic & medicinal chemistry letters, , Jun-15, Volume: 17, Issue:12, 2007