perfluorotripropylamine profile

Perfluorotripropylamine (PFTPA) is a highly fluorinated tertiary amine with a unique chemical structure. It is a colorless liquid with a low boiling point and is known for its exceptional chemical and thermal stability. PFTPA is synthesized through a multi-step process involving the reaction of perfluoropropylene with ammonia. Its high resistance to oxidation and hydrolysis makes it a valuable material in various applications, including high-performance lubricants, dielectric fluids, and heat transfer agents. The compound's unique properties have led to extensive research on its potential uses in advanced electronic devices, aerospace engineering, and other industries. Notably, PFTPA has been explored for its ability to suppress arcing and improve the performance of electrical insulators. Further studies focus on its potential applications in developing high-energy density capacitors and other energy storage devices. Its inertness and low toxicity make it a promising candidate for various industrial applications. However, its environmental impact and potential bioaccumulation require careful consideration for responsible usage.'

ID Source	ID
PubMed CID	67645
CHEMBL ID	2104877
CHEBI ID	38850
SCHEMBL ID	64251
MeSH ID	M0118050

Synonym
c9f21n
1-propanamine, 1,1,2,2,3,3,3-heptafluoro-n,n-bis(heptafluoropropyl)-
perfluamine
CHEBI:38850 ,
f-tripropylamine
heneicosafluorotripropylamine
1,1,2,2,3,3,3-heptafluoro-n,n-bis(heptafluoropropyl)-1-propanamine
338-83-0
heptafluoro-n,n-bis(heptafluoropropyl)-1-propanamine
1,1,2,2,3,3,3-heptafluoro-n,n-bis(heptafluoropropyl)propan-1-amine
ftpa
perfluorotripropylamine
1,1,2,2,3,3,3-heptafluoro-n,n-bis(1,1,2,2,3,3,3-heptafluoropropyl)propan-1-amine
AKOS005762874
perfluaminum
3t396uk091 ,
perfluamina [spanish]
perfluamine [inn:ban]
ec 206-420-2
perfluamina
unii-3t396uk091
einecs 206-420-2
hsdb 7102
perfluaminum [latin]
1-propanamine, 1,1,2,2,3,3,3-heptafluoro-n,n-bis(1,1,2,2,3,3,3-heptafluoropropyl)-
4-[(e)-(3-bromoinden-1-ylidene)methyl]-n,n-dimethyl-aniline
A821980
perfluorotri-n-propylamine
CHEMBL2104877
FT-0602703
fluosol da perfluorotripropylamine
fluosol da perfluorotripropylamine [mi]
perfluorotri-n-propylamine [vandf]
perfluamine [hsdb]
perfluamine [inn]
tris(heptafluoropropyl)amine
SCHEMBL64251
FD2054
DTXSID9059834
tris(perfluoropropyl)amine
Q-201547
mfcd00042589
JAJLKEVKNDUJBG-UHFFFAOYSA-N ,
1-propanamine, 1,1,2,2,3,3,3-heptafluoro-n,n-bis(1,1,2,2,3,3,3-heptafluoropropyl)- [perfluamine]
CS-0028173
HY-108299
AS-48924
Q27117994
perfluorotripropylamine;ftpa;tris(perfluoropropyl)amine
tris-heptafluoropropyl-amine
1,1,2,2,3,3,3-heptafluoro-n,n-bis(1,1,2,2,3,3,3-heptafluoropropyl)-1-propanamine
perfluoro-tri-n-propylamine

Role	Description
blood substitute	A substance that can carry oxygen to and carbon dioxide away from the tissues when introduced into the blood stream. Blood substitutes are used to replace hemoglobin in severe hemorrhage and also to perfuse isolated organs.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
organofluorine compound	An organofluorine compound is a compound containing at least one carbon-fluorine bond.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	17 (58.62)	18.7374
1990's	8 (27.59)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (6.90)	24.3611
2020's	2 (6.90)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	30 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
aminolevulinic acid Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.. 5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.	7.6	1	4-oxo monocarboxylic acid; amino acid zwitterion; delta-amino acid	antineoplastic agent; dermatologic drug; Escherichia coli metabolite; human metabolite; mouse metabolite; photosensitizing agent; plant metabolite; prodrug; Saccharomyces cerevisiae metabolite
hydrogen Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.. dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.	1.96	1	elemental hydrogen; elemental molecule; gas molecular entity	antioxidant; electron donor; food packaging gas; fuel; human metabolite
sodium fluoride [no description available]	2.1	1	fluoride salt	mutagen
krypton Krypton: A noble gas that is found in the atmosphere. It has the atomic symbol Kr, atomic number 36, atomic weight 83.80, and has been used in electric bulbs.	1.96	1	monoatomic krypton; noble gas atom; p-block element atom
perfluorodecalin perfluorodecalin: RN given refers to parent cpd without isomeric designation. perfluorodecalin : A fluorocarbon that is decalin in which every hydrogen is replaced by fluorine. Capable of dissolving large quantities of oxygen, it has been used as the basis of an artificial blood substitute.	4.05	15	fluorocarbon	blood substitute; solvent
perfluorotributylamine perfluorotributylamine: perfluorochemical (3M Co) artificial O(2) carrier. perfluorotributylamine : An organofluorine compound that is tributylamine in which all the hydrogens have been replaced by fluorine atoms.	1.99	1	organofluorine compound	blood substitute; greenhouse gas; solvent
xenon Xenon: A noble gas with the atomic symbol Xe, atomic number 54, and atomic weight 131.30. It is found in the earth's atmosphere and has been used as an anesthetic.	1.96	1	monoatomic xenon; noble gas atom; p-block element atom
fluorine Fluorine: A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as fluoride (FLUORIDES) to prevent dental caries.	2.66	3	diatomic fluorine; gas molecular entity	NMR chemical shift reference compound
poloxalene Poloxalene: A copolymer of polyethylene and polypropylene ether glycol. It is a non-ionic polyol surface-active agent used medically as a fecal softener and in cattle for prevention of bloat.. pluronic : A triblock copolymer composed of a central hydrophobic chain of poly(propylene oxide) flanked by two hydrophilic chains of poly(ethylene oxide).	2.9	4	epoxide
perfluoro-n-methyldecahydroisoquinoline [no description available]	1.97	1	organofluorine compound	blood substitute
cyclic gmp Cyclic GMP: Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed). 3',5'-cyclic GMP : A 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine.	1.97	1	3',5'-cyclic purine nucleotide; guanyl ribonucleotide	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite

Condition	Relationship Strength	Studies
Chronic Insomnia [description not available]	2.6	1
Sleep Initiation and Maintenance Disorders Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.	2.6	1
Carcinoma, Epidermoid [description not available]	2.6	1
Cancer of Skin [description not available]	2.6	1
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)	2.6	1
Skin Neoplasms Tumors or cancer of the SKIN.	2.6	1
Disease Exacerbation [description not available]	2.1	1
Brain Vascular Disorders [description not available]	1.96	1
Cerebrovascular Disorders A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.	1.96	1
Bleeding [description not available]	1.96	1
Hemorrhage Bleeding or escape of blood from a vessel.	1.96	1
Emesis [description not available]	1.99	1
Acathisia, Drug-Induced [description not available]	1.99	1
Neutropenia A decrease in the number of NEUTROPHILS found in the blood.	1.99	1
Vomiting The forcible expulsion of the contents of the STOMACH through the MOUTH.	1.99	1
Brain Hemorrhage, Cerebral [description not available]	1.97	1
Blood Pressure, High [description not available]	1.97	1
Cerebral Hemorrhage Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.	1.97	1
Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.	1.97	1
Anoxemia [description not available]	2.37	2
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	1.97	1
Blood Pressure, Low [description not available]	1.97	1
Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms.	2.37	2
Hypotension Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.	1.97	1
Coronary Heart Disease [description not available]	2.66	3
Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.	2.66	3
Adenocarcinoma, Basal Cell [description not available]	1.97	1
Experimental Mammary Neoplasms [description not available]	1.97	1
Adenocarcinoma A malignant epithelial tumor with a glandular organization.	1.97	1
Anemia A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.	1.96	1
Adenoma, beta-Cell [description not available]	1.97	1
Cancer of Pancreas [description not available]	1.97	1
Insulinoma A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.	1.97	1
Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).	1.97	1

perfluorotripropylamine

Cross-References

Synonyms (52)

Roles (1)

Drug Classes (1)

Research

Studies (29)

Market Indicators

Research Demand Index: 22.79

Study Types