spermine has been researched along with Hypertension in 9 studies
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigated the effect of orally administered synthetic kukoamine A on BP in the Spontaneously Hypertensive Rat (SHR) laboratory animal model of hypertension." | 8.12 | Influence of oral administration of kukoamine A on blood pressure in a rat hypertension model. ( Bunn, BJ; Butts, CA; Dinnan, H; Hedderley, DI; Lill, RE; Martell, S; McGhie, TK; Middlemiss-Kraak, S, 2022) |
| "Polyamines (putrescine, spermidine and spermine) play an important role in the development of hypertension and in the expression of atrial natriuretic peptide (ANP), a cardiac hormone involved in the regulation of blood pressure." | 7.71 | Hypertension in normotensive and hypertensive rats by spermine ingestion. ( Li, S; Tipnis, UR, 2001) |
| "The aim was to investigate the involvement of polyamines in the development of cardiovascular hypertrophy in a rat angiotensin II infusion model of hypertension." | 7.69 | Role of polyamines in hypertension induced by angiotensin II. ( Hughes, AD; Ibrahim, J; Schachter, M; Sever, PS, 1995) |
| " We investigated the effect of orally administered synthetic kukoamine A on BP in the Spontaneously Hypertensive Rat (SHR) laboratory animal model of hypertension." | 4.12 | Influence of oral administration of kukoamine A on blood pressure in a rat hypertension model. ( Bunn, BJ; Butts, CA; Dinnan, H; Hedderley, DI; Lill, RE; Martell, S; McGhie, TK; Middlemiss-Kraak, S, 2022) |
| "Polyamines (putrescine, spermidine and spermine) play an important role in the development of hypertension and in the expression of atrial natriuretic peptide (ANP), a cardiac hormone involved in the regulation of blood pressure." | 3.71 | Hypertension in normotensive and hypertensive rats by spermine ingestion. ( Li, S; Tipnis, UR, 2001) |
| "The aim was to investigate the involvement of polyamines in the development of cardiovascular hypertrophy in a rat angiotensin II infusion model of hypertension." | 3.69 | Role of polyamines in hypertension induced by angiotensin II. ( Hughes, AD; Ibrahim, J; Schachter, M; Sever, PS, 1995) |
| " The effects of chronic administration of alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase and thus polyamine biosynthesis, on vascular polyamine contents, structure, and function as well as the development of hypertension was studied." | 1.28 | Polyamines, vascular smooth muscle, and deoxycorticosterone acetate-salt hypertension. ( Newman, PS; Olson, JW; Soltis, EE, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Butts, CA | 1 |
| Hedderley, DI | 1 |
| Martell, S | 1 |
| Dinnan, H | 1 |
| Middlemiss-Kraak, S | 1 |
| Bunn, BJ | 1 |
| McGhie, TK | 1 |
| Lill, RE | 1 |
| Liu, R | 1 |
| Persson, AE | 1 |
| Brennan, LA | 1 |
| Wedgwood, S | 1 |
| Black, SM | 1 |
| Burke, M | 1 |
| Neufeld, E | 1 |
| Goldberg, S | 1 |
| Chayen, R | 1 |
| Ibrahim, J | 1 |
| Schachter, M | 1 |
| Hughes, AD | 1 |
| Sever, PS | 1 |
| Bergeron, RJ | 1 |
| Wiegand, J | 1 |
| Sninsky, CA | 1 |
| Katovich, MJ | 1 |
| Tipnis, UR | 1 |
| Li, S | 1 |
| Sohn, HS | 1 |
| Park, YN | 1 |
| Lee, SR | 1 |
| Soltis, EE | 1 |
| Newman, PS | 1 |
| Olson, JW | 1 |
9 other studies available for spermine and Hypertension
| Article | Year |
|---|---|
Influence of oral administration of kukoamine A on blood pressure in a rat hypertension model.
Topics: Administration, Oral; Animals; Blood Pressure; Hypertension; Mice; Rats; Rats, Inbred SHR; Rats, Inb | 2022 |
Effects of nitric oxide on P2Y receptor resensitization in spontaneously hypertensive rat mesangial cells.
Topics: Adenosine Triphosphate; Animals; Arginine; Calcium; Cells, Cultured; Cyclic GMP; Cytosol; Enzyme Inh | 2002 |
The overexpression catalase reduces NO-mediated inhibition of endothelial NO synthase.
Topics: Adenoviridae; Animals; Blotting, Western; Catalase; Cells, Cultured; Hydrogen Peroxide; Hypertension | 2002 |
Lack of inhibition of diamine oxidase during hydralazine therapy.
Topics: Amine Oxidase (Copper-Containing); Cadaverine; Humans; Hydralazine; Hypertension; Male; Putrescine; | 1984 |
Role of polyamines in hypertension induced by angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Cardiomegaly; Disease Models, Animal; Heart Ventricles; Hypertension | 1995 |
The impact of polyamine analogues on the blood pressure of normotensive and hypertensive rats.
Topics: Amines; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; R | 1995 |
Hypertension in normotensive and hypertensive rats by spermine ingestion.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Heart Ventricles; Hypertension; Myocardium; Poly | 2001 |
Effect of immobilization stress on brain polyamine levels in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Acute Disease; Animals; Biogenic Polyamines; Brain; Chronic Disease; Frontal Lobe; Hippocampus; Hype | 2002 |
Polyamines, vascular smooth muscle, and deoxycorticosterone acetate-salt hypertension.
Topics: Acetylcholine; Animals; Aorta; Arteries; Blood Pressure; Body Weight; Desoxycorticosterone; Dose-Res | 1991 |